SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
PARTICULATE LIPID PHARMACEUTICAL COMPOSITION

A particulate lipid pharmaceutical composition comprises a particulate solid non-lipid carrier and an oil-in-water emulsion on the carrier. The emulsion comprises a dissolved or dispersed pharmacologically active agent. The oil-in-water emulsion is released from the carrier on contact with an aqueous media to form an oil-in-water emulsion in the media. Also disclosed is a method of producing the composition and a tablet containing it; sachets and capsules filled with the composition; use of the composition and the tablet as a medicine; a method of administering the composition to a patient.
SU-E-T-421: Feasibility Study of Volumetric Modulated Arc Therapy with Constant Dose Rate for Endometrial Cancer

Purpose: To investigate the feasibility, efficiency, and delivery accuracy of volumetric modulated arc therapy with constant dose rate (VMAT‐CDR) for whole pelvic radiotherapy of endometrial cancer. Methods: The nine‐field intensity‐modulated radiotherapy (IMRT), volumetric modulated arc therapy with variable dose rate (VMAT‐VDR), and VMAT‐CDR plans were created for 9 patients with endometrial cancer undergoing whole pelvic radiotherapy. The dose distribution of planning target volume (PTV), organs at risk (OARs) and normal tissue (NT) were compared. The monitor units (MUs) and treatment delivery time were also evaluated. For each VMAT‐CDR plan, a dry run was performed to assess the dosimetric accuracy with MatriXX from IBA. Results: Compared with IMRT, the VMAT‐CDR plans delivered a slightly greater V20 of bowel, bladder, pelvis bone and normal tissue, but significantly decreased the dose to the high dose region of rectum and pelvis bone. The monitor units decreased from 1105 with IMRT to 628 with VMAT‐CDR. The delivery time also decreased from 9.5 min to 3.2 min. Very similar dose distribution was found in the VMAT‐VDR and VMAT‐CDR plans. The average gamma pass rate was 95.6% at the 3%/3 mm criteria with MatriXX pre‐treatment verification for nine patients. Conclusion: Volumetric modulated arc therapy with constant dose rate can achieve comparable plan quality with significant shorter delivery time and smaller number of MUs compared with IMRT for endometrial cancer patients undergoing whole pelvic radiotherapy. It can be accurately delivered and be an alternative to IMRT on the linear accelerator without variable dose rate capability. This work is supported by the grant project: National Natural Science Foundation of China (No. 81071237).
Application Of Signed Graph In Decision Making

A signed graph may be defined as an ordered pair (G, Ïƒ) where G= (V, E) is the graph and Ïƒ is a function called signature or sign mapping from E to the sign group {+, -}. People or friends are considered as the vertices and the relationships between these friends are considered as the edges. '+' sign is assigned to the edge for good relationship and '-' sign for bad relationship between the friends. Two terms friendship matrix or â€œjudgement matrix and character point C.P are introduced in this paper. Using the concept of friendship matrix and C.P in various fields the characteristics or performances could be evaluated. In this paper different problems have been considered and analysed with the help of signed graph.
Centre of excellence for autonomous and cooperative robotic systems

The overall objective of the project is to create a Centre of Excellence for Autonomous and Cooperative Robotic Systems in Croatia (ACROSS CoE), which will be at the forefront of research and innovation of novel methodologies and advanced engineering approaches in the targeted domains. ACROSS CoE will be created and run as a long-term joint venture between the UNIZG-FER ̵ University of Zagreb Faculty of Electrical Engineering and Computing, the KTH ̵ Royal Institute of Technology, and the ICENT ̵ Innovation Centre Nikola Tesla. To achieve the overall objective, the proposal focuses on long-term objectives for Teaming Phase 2 and on one-year objective for Teaming Phase 1. Long-term objectives of the Phase 2 and beyond are: (i) Reinforcing scientific capacity and innovation performances in autonomous and cooperative robotic systems, (ii) Increasing scientific visibility and reputation at international level, and (iii) Improving responses to socioeconomic needs of Croatia. ACROSS CoE will achieve these objectives by striving for high quality research, in line with international standards of excellence, and by directing its research towards areas serving the technological needs identified by the Croatian Smart Specialisation Strategy. The ultimate objective of the Phase 1 is to produce an extensive, detailed, and robust Business Plan for ACROSS CoE; and to achieve this, the plan will be built upon (i) Assessment of the existing ACROSS ecosystem and (ii) Development of roadmaps for achieving ACROSS CoE excellence. The ACROSS project is relevant to the work programme since the main goal is to create a new Centre of Excellence in Croatia, a low R&I performing country, by building upon partnership with KTH, a world leading scientific and innovation institution. Creation of the ACROSS CoE will help Croatia in attaining a competitive position in the global value chains, thus also contributing to Europe’s competitiveness and its ability to address future societal challenges.
Energy efficient mortgage market implementation plan

The European Union (EU) has set itself ambitious climate change targets. The scale of investment needed to meet the energy savings targets alone is estimated at €180 billion p.a., three quarters of which is accounted for by energy efficiency in buildings. In light of the link between buildings and mortgages, the EU-funded Energy Efficient Mortgages Initiative (EEMI)[1] sought to bridge some of this gap by way of the energy efficient mortgage (EEM) product and framework. However, experience gained indicates the development of the EEM market goes far beyond designing the product and requires the integration of a complex web of stakeholders.  

The Energy Efficient Mortgage Market Implementation Plan (EeMMIP) will build on efforts to develop EEM by delivering an integrated market and a blueprint for established and emerging markets around the globe. The Project will conduct an analysis of the current market systems relevant to the development of an EEM market and establish demonstrators to support the demonstration of the end-to-end customer journey and EEM life-cycle. It will establish market-based governance and an EEM Label to support recognition of and confidence in EEM and facilitate access to quality information for market participants. It will deliver guidance for the inclusion of energy efficiency in credit risk assessments for lending institutions and supervisors and policy recommendations for the prudential framework in line with the principle of risk sensitivity and promote a well-functioning banking market. Finally, it will support global take-up of EEM through the Label and institutional cooperation. EeMMIP responds to the objectives of the EU in the areas of sustainable finance and climate change, all against the background of Capital Markets Union, and aims to influence the entire value chain, from consumer to bond investor, stimulating mentality change and securing energy efficiency in market attitudes and best practices both in Europe and globally.
Establishing services enhancing the innovation management capacity of sme's in the enterprise europe network

Main task is to establish the services “Enhancing the innovation management capacity of SMEs” within the Enterprise Europe Network with the intention to enhance SME’s potential in a successful result of their participation in The SME instruments project and to assist particularly promising SMEs in enhancing their innovation management capacities. 
The services are aimed at SMEs in Iceland with a great potential for international growth, but lack knowledge, skills or ability to manage innovation activities. Highly qualified staff of Enterprise Europe Network at the Innovation Center Iceland possesses the skills required and in-depth knowledge of the support required to enable companies to reach their potential.
Association between serum uric acid levels and incidence of nonalcoholic fatty liver disease in users of preventive medicine service in southern Brazil: a retrospective study

Abstract Background Nonalcoholic fatty liver disease (NAFLD) is a silent disease with increasing prevalence. High levels of serum uric acid (SUA) have been associated with cardiometabolic diseases, yet the possible association between SUA levels and NAFLD is not elucidated. This article aim is to evaluate the possible association between SUA and NAFLD in a Brazilian population. Methods This retrospective study evaluated patients submitted to two evaluations between 2015 and 2016 at a preventive medicine service. The diagnosis of NAFLD was performed through abdominal ultrasound, and its progression was defined as favorable or unfavorable according to the degrees of steatosis. Patients with hyperthyroidism, pregnancy, viral hepatitis, use of methotrexate or anabolic steroids, significant alcohol consumption were excluded. Possible confounding factors were evaluated through a multivariate model. Results A total of 279 patients were included in the final sample. In the first evaluation, 20.1% were women and the mean age was 46.9 (± 7.9) years, with a mean body mass index of 27.3 (± 4.0) kg/m 2 . About 26.9% of the individuals were diagnosed with NAFLD, and the mean of SUA levels was 5.7 (± 1.4) mg/dL; a favorable progression of NAFLD was observed in 79.2% of the patients, and the SUA levels at baseline were not significantly associated with the NAFLD progression ( p = 0.43). Conclusions Despite NAFLD high prevalence, SUA levels were not significantly associated with NAFLD progression in one year in this sample.
Point cloud technology and 2D computational flow dynamic modeling for rapid hazards and disaster risk appraisal on Yellow Creek fan, Southern Alps of New Zealand

Glacial recession in Alpine Valleys uncorks low-altitude tributary valleys that spill trapped sediments in the sediment cascade, in turn generating sediment-related hazards and flood hazards. Within this complex, the present contribution investigates the transition zone between the tributary and the main valley at Fox Glacier, New Zealand, where glacier recession has allowed the development of large debris flow fans. As the valley is narrow and its geomorphology is rapidly evolving, 3D point cloud technologies based on aerial photogrammetry from UAV or ground and airborne laser technologies are essential to understand the geomorphology and generate boundary conditions to run hazard simulations such as debris flows. Using airborne structure from motion photogrammetry with ground control points collected by RTK-GNSS, we investigated (1) the geomorphology of the valley to understand its evolution and (2) the role of this recent evolution on the flood hazards at the Yellow Creek debris flow fan. The geomorphology of the Fox River valley is a typical U-shape valley with steep valley walls that command the valley by more than 1000 m. The valley walls are connected to the bottom of the valley by active sediment aprons and debris flow fans at the exit of the tributaries. The slopes present several topographic steps or noses on both the aprons and the debris flow fans. By comparison with the glacial recession, they can be related to past locations of the limits of the glacier. On Straight Creek fan, the ridges are perpendicular to the valley and divide the fan between an overgrown half downstream the Fox Valley and an upstream section thinner and smaller. This pattern was also created by the presence of the glacier that stopped the development of the fan on its right (upstream half) while developing the true left hand side of the fan. On the other side of the valley, the debris flow fan of Yellow Creek presents a series of deep trough that control water flows. Flood simulations show that these controls can be overcome and instead of being channeled in other sub-channels, the flow tends to spread on the true right (downstream) end of the fan as a sheet flow. In the 2014 state of the fan, the safest location was thus on the true left half of the fan towards the glacier. Such information is essential as tourists occupy the valley and walk towards the glacier the whole year.
Bioavailability of plant sterol-enriched milk-based fruit beverages: In vivo and in vitro studies

Abstract This study for the first time compares the in vivo (response in serum from individuals of an interventional study) and in vitro effects (bioaccessibility determined from simulated gastrointestinal digestion) of two plant sterol (PS)-enriched milk-based fruit beverages (with and without tangerine fruit juice rich in β-cryptoxanthin (β-Cx)) in order to assess their suitability as PS-enriched food matrixes, and the possible interactions between the two bioactive compounds (β-Cx and PS) that might affect their absorption. The randomized, double-blind, crossover study (performed in 36 postmenopausal women) showed the β-sitosterol and campesterol serum concentrations after four weeks of consumption of the beverages (1.5 g PS/day) to increase significantly (ranging 1.6–2.4 µg/mL and 0.3–0.4 µg/mL, respectively), thereby confirming suitability as matrices for PS-enrichment. The results therefore indicated similar behavior of PS supplied by these beverages and evaluated through in vitro or in vivo assays, independently of whether the samples contained β-Cx or not.
Apoyo a las empresas registradas en virtud de la Ley de turismo como operador turístico o agente de viajes para superar las consecuencias económicas de la pandemia de COVID-19

Apoyo a las empresas registradas en virtud de la Ley de turismo como operador turístico o agente de viajes para superar las consecuencias económicas de la pandemia de COVID-19
How LCA contributes to the environmental assessment of higher order effects of ICT application: A review of different approaches

Abstract Information and communication technology (ICT) is often considered a technology for reducing environmental emissions by increasing energy and resource efficiencies of processes. However, due to other effects of ICT, such as rebound and induction effects, the net benefits of ICT in terms of environmental impact are by no means assured. Even though the relevance of indirect or higher order effects has become a well-known issue in recent years, their environmental assessment remains controversial. Life cycle assessment (LCA) is one of the most established environmental assessment methods for modelling the environmental effects of goods and services throughout their life cycle. Although LCA is traditionally rather product-focused, there exist also LCA-based approaches to assess higher order effects of technology replacement and optimization. This paper examines whether and how LCA case studies on environmental effects of ICT already take into account related higher order effects. A systematic review of scientific literature published since 2005 has been conducted and 25 case studies were analyzed in detail. The following research questions were addressed: i) Which products are assessed? ii) Which higher order effects of ICT are considered; and iii) how is the integration of higher order effects methodically realized? The results show that few case studies were concerned with the environmental effects of the introduction of ICT services in commerce, telework and monitoring and control. Most studies investigated the substitution of certain media with electronic devices or digital services. It was found that technology-based higher order effects, such as optimization and substitution, are usually included in the assessment by choosing comparative study designs, while user-related higher order effects, such as rebound effects and induction effects, are less often considered. For the latter effects, methodological integration was mainly provided by scenario modelling and sensitivity analysis. Overall, most studies chose an attributional LCA approach. It can be concluded from the results that, in particular, user-related effects such as rebound effects have not yet been frequently included in the environmental assessment of ICT. The identified research gaps include in particular interdisciplinary approaches on how changing use patterns can be more strongly observed in LCA.
Understanding the Entitlement to Security through ESC Rights

The Universal Declaration of Human Rights establishes that everyone’s dignity and freedom to develop as a person are secured through economic, social and cultural rights. This volume examines the origins of the article of the Declaration that introduced the purpose of economic, social and cultural rights in this way and recognized that every member of society is entitled to their realization through national effort and international cooperation. The article’s concepts have been the subject of significant articulation and interpretation. Accordingly, the book analyzes the meaning and application of economic, social and cultural rights and the nature of the related obligations developed in the International Covenant on Economic, Social, and Cultural Rights and other international instruments. The book also explores the contribution of the article's legal concepts to philosophical theories of social justice and increasingly to the practice expected of States, individually and in cooperation with international organizations and non-state actors in development and other activities. This volume should provide a convenient tool for human rights advocates, practitioners, lawyers, scholars, and others involved with and interested in the role of human rights in seeking economic, social and cultural security for all.
The bacteriological composition of biomass recovered by flushing an operational drinking water distribution system

This study investigates the influence of pipe characteristics on the bacteriological composition of material mobilised from a drinking water distribution system (DWDS) and the impact of biofilm removal on water quality. Hydrants in a single UK Distribution Management Area (DMA) with both polyethylene and cast iron pipe sections were subjected to incremental increases in flow to mobilise material from the pipe walls. Turbidity was monitored during these operations and water samples were collected for physico-chemical and bacteriological analysis. DNA was extracted from the material mobilised into the bulk water before and during flushing. Bacterial tag-encoded 454 pyrosequencing was then used to characterize the bacterial communities present in this material. Turbidity values were high in the samples from cast iron pipes. Iron, aluminium, manganese and phosphate concentrations were found to correlate to observed turbidity. The bacterial community composition of the material mobilised from the pipes was significantly different between plastic and cast iron pipe sections (p < 0.5). High relative abundances of Alphaproteobacteria (23.3%), Clostridia (10.3%) and Actinobacteria (10.3%) were detected in the material removed from plastic pipes. Sequences related to Alphaproteobacteria (22.8%), Bacilli (16.6%), and Gammaproteobacteria (1.4%) were predominant in the samples obtained from cast iron pipes. The highest species richness and diversity were found in the samples from material mobilised from plastic pipes. Spirochaeta spp., Methylobacterium spp. Clostridium spp. and Desulfobacterium spp., were the most represented genera in the material obtained prior to and during the flushing of the plastic pipes. In cast iron pipes a high relative abundance of bacteria able to utilise different iron and manganese compounds were found such as Lysinibacillus spp., Geobacillus spp. and Magnetobacterium spp.
Fertility treatment and dichorionic discordant twins – are they related?

Abstract Objective: This prospective cohort study evaluated the relationship between fertility treatments and the prevalence and outcomes of dichorionic discordant twins. This issue has gained importance due to twin gestations resulting from fertility treatments. Study design: Mothers of dichorionic twin pregnancies achieved in a single fertility clinic by assisted reproduction techniques, who had completed the first trimester of the pregnancy, were prospectively enrolled. Pregnancies with major fetal anomalies were excluded. Data regarding concordant and discordant twins based on the fertility treatments given to achieve the pregnancies were analyzed to determine the prevalence of discordance and pregnancy outcomes. Results: A total of 571 dichorionic twin pregnancies were available for evaluation. Fertility treatments modalities, sperm quality and implantation of cultured and thawed embryos did not influence the rate and severity of discordant twins. Increased hospitalization rates were found among discordant (n=108) compared to concordant (n=463) twins (47.2% vs. 31.3%, P&lt;0.0001) and higher rates of betamethasone treatment (65.7% vs. 28.9%, P&lt;0.0001). Secondary analysis of discordant pregnancies with a growth restricted twin, revealed the same results. We found no association between various fertility treatments and twin discordance. Conclusions: Our data suggest that fertility treatments do not play a major role in the pervasiveness and outcome of discordant twin pregnancies.
Urinary parameters of Trichechus inunguis (Mammalia, Sirenia): reference values for the Amazonian Manatee

The Amazonian manatee, Trichechus inunguis (Natterer 1883) is endemic to the Amazon Basin and is currently considered a vulnerable species. In order to establish normality ranges of urinary parameters to help monitor the health of this species in captivity, chemical urinalyses were performed on twelve males and nine females of various age groups. Urine was collected once a month for twelve months in the tanks just after being drained, by placing stainless steel containers under the genital slit of females and applying abdominal massages to males in order to stimulate urination. Quantitative data of glucose, urea, creatinine, uric acid and amylase levels were obtained using colorimetric spectrophotometry. Dip strips were also useful for routine analyses, despite only providing qualitative results. Normal range to glucose levels, regardless of sex or age class, was 3.0 to 3.6 mgxdL-1, coinciding with qualitative values of glucose measured by dip strips. Statistical differences observed in some parameter levels suggest that some urine parameters analysed must take into consideration the sex and the age class of the animal studied, being these differences less remarkable in creatinine and amylase levels. To this last one, statistical difference was detected only in the calve's urine (7.0 to 11.5 mgxdL-1) compared to other age classes samples (4.1 to 5.3 mgxdL-1). The results presented here may be used as comparative data in future research on urinalysis in related species.