SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Renewable low temperature district

District heating (DH) systems are one of the most energy efficient heating systems in urban environments, with proven reliability within many decades already. DHs have traditionally been designed to be operated in a hierarchized way, with central energy production facilities delivering heat to a variety of distributed consumption locations.
DHs are identified as key systems to achieve the de-carbonization of heating energy in European Cities. Renewable and waste heat sources are foreseen at the same time as de-carbonized heat sources and the way to guarantee competitive energy costs with limited influence of fossil fuel supply price volatility. To achieve this, conversion of DHs is needed regarding:
- The reduction of their operation temperature to avoid current technical constraints in the integration of low-grade industrial heat sources,
- The introduction of larger shares of renewable energy sources (RES) in the DH network.
- The introduction of distributed heat sources (reject heat from cooling equipment...).
- To guarantee economic viability with the trend of DH heat load reduction due to the evolution of the building stock toward NZEB (Near Zero Energy Buildings).
RELaTED will provide an innovative concept of decentralized Ultra-Low Temperature (ULT) DH networks, which allow for the incorporation of low-grade heat sources with minimal constraints. Also, ULT DH reduce operational costs due to fewer heat losses, better energy performance of heat generation plants and extensive use of de-carbonized energy sources at low marginal costs.
The RELaTED ULT DH concept will be demonstrated in four complementary operation environments (new and existing DH, locations, climatic conditions, dimension…) in Denmark, Estonia, Serbia and Spain.
RELaTED approach will follow the strategy of the electrical smart grids, in which energy generation is decentralized and consumers evolve to prosumers (they consume and produce energy).
Audit Quality

The importance of fostering more accurate audits has been heightened by a series of high-profile accounting scandals at the beginning of the millennium. These scandals prompted more stringent regulations over corporate governance and financial reporting and the creation of audit oversight bodies as the Public Company Accounting Oversight Board (PCAOB) in the United States and the Public Oversight Board (POB) in the United Kingdom. In parallel, the growing globalization of business has brought forth calls for adherence to a common set of International Financial Reporting Standards (IFRS). Even if a common standard is promulgated, it will not lead to similar results if implementation differs across countries. Therefore, it is important to investigate the auditing regulatory regimes in different nations and the status of cross-border audit inspections. Accordingly, we begin by describing the cross-national institutions (e.g., the International Federation of Accountants [IFAC]) that impact national regulatory choices. Then we survey the audit regulatory practices of public company auditors of a select group of major economic powers and based on this analysis, we discuss the challenges and obstacles to engaging in intra-national audit, cross-national audit/inspections, and the challenges posed by differences in auditing standards used in various linked (e.g., by joint ventures, etc.) nations. We include in this discussion the effects of national culture, investor legal protection, economic development, and differing financial standard sources.
Potencial hídrico da captação de água de chuva em edificações da Universidade Federal de Pernambuco.

The science recognizes the water is essentialto the life maintains, because it is a basic element in all live organisms, besides water maintains the environment equilibrium and it is a mainly component in many human activists as well as hygiene, cooking, manufactory production, drinking, etc. The future scarcity of potable water has been a major motivating factor for research alternatives in order to supply the next generation with general necessities as well as to promote the rational use of water. Considering that water is directly correlated to the general population’s quality of life as well as all forms of life species on our planet, it is critical that civil society as well as the government and public institutions look for mechanisms to preserve water. This study proposed evaluating the potentiality to colletrain water in the Agreste’s campus of the Federal University of Pernambuco and the water reuse in restrooms. In order to develop this study, previous data was collected on water consumption on restrooms and monthly water consumption historically on campus. The results demonstrate that a rain water catchment system has a potential to provide more than 63,1% of the total utilized volume in the Agreste’s campus between March and July.
‘Negative’ and ‘positive catalysis’: complementary principles that shape the catalytic landscape of enzymes

Our understanding of enzyme catalysis is dominated by transition state theory. According to this concept, an enzymatic reaction is guided along a desired reaction coordinate through the stabilization of favorable transition state. But how much is the outcome of an enzyme reaction controlled by the destabilization of unwanted transition states? Here, we revive and critically review the hypothesis that the active site of enzymes also features elements of 'negative catalysis'. We provide examples that show that enzyme catalysis can be achieved by the combined action of positive and negative constraints at the active site of an enzyme. This integrated view of enzyme catalysis has direct consequences for our studies on the catalytic landscape of enzymes, as well as current efforts in enzyme engineering and the de novo-design of enzymes.
Parameter variability estimation using stochastic response surface model updating

Abstract From a practical point of view, uncertainties existing in structural parameters and measurements must be handled in order to provide reliable structural condition evaluations. At this moment, deterministic model updating loses its practicability and a stochastic updating procedure should be employed seeking for statistical properties of parameters and responses. Presently this topic has not been well investigated on account of its greater complexity in theoretical configuration and difficulty in inverse problem solutions after involving uncertainty analyses. Due to it, this paper attempts to develop a stochastic model updating method for parameter variability estimation. Uncertain parameters and responses are correlated through stochastic response surface models, which are actually explicit polynomial chaos expansions based on Hermite polynomials. Then by establishing a stochastic inverse problem, parameter means and standard deviations are updated in a separate and successive way. For the purposes of problem simplification and optimization efficiency, in each updating iteration stochastic response surface models are reconstructed to avoid the construction and analysis of sensitivity matrices. Meanwhile, in the interest of investigating the effects of parameter variability on responses, a parameter sensitivity analysis method has been developed based on the derivation of polynomial chaos expansions. Lastly the feasibility and reliability of the proposed methods have been validated using a numerical beam and then a set of nominally identical metal plates. After comparing with a perturbation method, it is found that the proposed method can estimate parameter variability with satisfactory accuracy and the complexity of the inverse problem can be highly reduced resulting in cost-efficient optimization.
<i>Retracted:</i> Impact of <scp>COVID</scp>‐19 pandemic on routine vaccination coverage of children and adolescents: A systematic review

Abstract Background and Aims Scientists and healthcare workers have expressed their concerns on the impacts of the COVID‐19 pandemic on vaccination coverage in children and adolescents. Therefore, we aimed to systematically review the studies addressing this issue worldwide. Methods We conducted a systematic search of relevant studies using the keywords on databases of PubMed, Web of Science, and Cochrane on May 22, 2021. The identified records were imported into EndNote software and underwent a two‐phase screening process consisting of title/abstract and full‐text screenings against inclusion criteria. The data of the included studies were summarized into a table and the findings were analyzed in a systematic approach. Results From 26 eligible studies, 21 studies demonstrated decreased vaccination rates in the children during the COVID‐19 pandemic, while three studies found increased or no significant changes only in influenza vaccination. The two remaining studies from Brazil and Sweden also showed no significant changes in vaccination rates in the children during the pandemic. Conclusion Most of the reports worldwide reported a decline or delay in vaccination at the time of the COVID‐19 pandemic. A sustained catch‐up program seems to be necessary, especially in low‐income countries, to avoid any vaccine dose missing. Facilitating the vaccination process is recommended, such as decreasing the waiting time for vaccination at the health center, addressing the fear and concerns related to COVID infection for parents, and enhancing vaccine availability, and promoting access in remote areas. Countries should ensure proper vaccination to prevent future pandemics related to vaccine‐preventable diseases.
Addressing the unemployment–mortality conundrum: Non-linearity is the answer

The effect of unemployment on mortality is the object of a lively literature. However, this literature is characterized by sharply conflicting results. We revisit this issue and suggest that the relationship might be non-linear. We use data for 265 territorial units (regions) within 23 European countries over the period 2000-2012 to estimate a multivariate regression of mortality. The estimating equation allows for a quadratic relationship between unemployment and mortality. We control for various other determinants of mortality at regional and national level and we include region-specific and time-specific fixed effects. The model is also extended to account for the dynamic adjustment of mortality and possible lagged effects of unemployment. We find that the relationship between mortality and unemployment is U shaped. In the benchmark regression, when the unemployment rate is low, at 3%, an increase by one percentage point decreases average mortality by 0.7%. As unemployment increases, the effect decays: when the unemployment rate is 8% (sample average) a further increase by one percentage point decreases average mortality by 0.4%. The effect changes sign, turning from negative to positive, when unemployment is around 17%. When the unemployment rate is 25%, a further increase by one percentage point raises average mortality by 0.4%. Results hold for different causes of death and across different specifications of the estimating equation. We argue that the non-linearity arises because the level of unemployment affects the psychological and behavioural response of individuals to worsening economic conditions.
Understanding small rna-mediated transposon control at the level of chromatin in the animal germline

Transposable elements—universal components of genomes—pose a major threat to genome integrity due to their mutagenic character. In all eukaryotic lineages small RNA pathways act as defense systems to protect the host genome against the activity of transposons. The central pathway in animals is the gonad-specific PIWI interacting RNA (piRNA) pathway, one of the most elaborate but also least understood small RNA silencing systems.

Here I propose to study the interplay between the piRNA pathway and chromatin biology in Drosophila with two aims: First, we will identify the factors and investigate the processes that underlie piRNA-guided silencing in the nucleus. Our objective is to understand how recruitment of an Argonaute protein to a nascent RNA mechanistically leads to the assembly of effector proteins that govern heterochromatin formation and transcriptional silencing. Second, we will study the biology of piRNA clusters, heterochromatic loci that encompass a library of transposon fragments and that act as the pathway’s memory system. Our goal is to uncover how a group of proteins—several of which are germline-specific variants of basic cellular factors—enable transcription within heterochromatin and control the downstream fate of the emerging non-coding RNAs. 

Our work centers on the piRNA pathway in Drosophila ovaries, undeniably the model system at the forefront of the field. By combining the strength of fly genetics with the power of genome-wide approaches we will uncover how heterochromatin on the one hand governs silencing and how the piRNA pathway on the other hand exploits it to facilitate the transcription of piRNA precursors. This will reveal fundamental insights into the co-evolution of transposons and host genomes. At the same time, by studying the piRNA pathway’s intersection with chromatin biology and transcription, we expect to reveal new insights into basic principles of gene expression.
Electrical conductance across self-assembled lipid bilayers

This study investigates electrical conduction across lipid bilayers that self-assemble in oil between a water drop and a hafnium oxide surface. Morphology and electrical properties of two bilayers formed from equal molar concentrations of sorbitan monooleate (Span 80) and sorbitan trioleate (Span 85) in dodecane are quantified and compared. The molecular structures of the two surfactants are quite similar, except that sorbitan monooleate contains one unsaturated lipid tail per molecule, whereas sorbitan trioleate contains three. We find that the leakage current density across both bilayers increases exponentially with electric field. The relative leakage current densities across the two bilayers scale with the packing density of lipid tails in the bilayers. This correlation provides evidence that the lipid tail interactions through thermal fluctuations provide a pathway of electrical conduction across the membrane.
POR LABBIO CRISTINA

PEDIDO DE CONCESSÃO PREVISTA NO ANÚNCIO PÚBLICO DE PEQUENAS SUBVENÇÕES A PME SUSPENSAS OU COM UMA GRAVE DIMINUIÇÃO DO VOLUME DE NEGÓCIOS
Strengthening the Competitiveness of the Alps as a Sustainable Health and Wellness Competence Destination

The supply of health services to an ageing European population will be a more and more important need. The Alpine Space has a long tradition in the field of health service based tourism. By the enlargement of the European Union especially in the field of health services based tourism the competition will change dramatically: Czech Republic, Poland and Hungary enter into the market with low prices because of low wages. 
As many destinations depend on a prosperous health services based tourism the projects focus lays in the field of strengthening the competitiveness by:
- defining, developing and managing a alpine quality standard of health and wellness services 
- strengthening the regional and transnational cooperation of players
- developing and adapting offers to the market trends 
- making use of the typical alpine resources in a sustainable way
- informing and consulting the publicity about the competences and services
- introducing a job fair and standardized education and training in the field of health services
Synthesis of bulk ion-imprinted polymers (IIPs) embedded with oleic acid coated Fe<sub>3</sub>O<sub>4</sub> for selective extraction of hexavalent uranium

A selective and reliable method for the extraction of trace quantities of U(VI) by the use of a magnetic U(VI) ion-imprinted polymer (IIP) was developed. In this study, oleic acid (OA) coated magnetite nano-particles were incorporated into the cross-linked polymeric matrix of the selective sorbent, in order to gain the physical advantages of separating the polymers. Many physico-chemical factors influence the adsorption process; uranyl ion uptake ability based on these parameters was investigated. The optimum parameters obtained were sample pH 4,50 mg of the magnetic polymer, a contact time of 45 min and an initial U(VI) concentration of 2 mg·l -1 . The adsorption capacities for the magnetic NIP and IIP were found to be 0.95 mg·g 1 and 1.21 mg·g -1 , respectively. The adsorption behaviour of U(VI) in the presence of other competing metal ions onto the cross-linked magnetic polymers was also examined in binary mixtures and the order of selectivity was found to be U(VI) > Pb(VI) > Ni(II). The resulting magnetic nano-composite polymers were found to be stable up to the sixth cycle of use and reuse. The Freundlich adsorption model was used for the mathematical description of the adsorption equilibrium and the adsorption kinetic data fitted the pseudo-first-order model with R2 > 0.92. Keywords: Bulk, magnetic imprinted polymers, oleic acid, uranium
A real-time Energy Management System for the integration of economical aspects and system operator requirements: Definition and validation

The present paper proposes a real-time EMS able to manage uncertainties in the forecasting data as well as economical aspects and system operator requirements. As far as the first aspect is concerned, the procedure is cyclically repeated at each time-step after that loads and renewable productions have been adjusted by means of real-time measurements. The economic aspects are performed by solving an optimization problem that minimizes the overall production cost and, therefore, it fixes the active power set point for all the programmable units. The Distribution System Operator (DSO) requirements in terms of active/reactive power management and voltage control, as requested by the majority of grid codes/standards, are satisfied (if possible) by tuning the reactive power of the programmable units. The proposed EMS has been applied and validated on University of Genoa Smart Polygeneration Microgrid (SPM) and it shows its efficacy in satisfying both the economic and power quality objectives.
Support for a coupling unit in a motor-vehicle transmission

The transmission comprises: a gearbox housed in a support housing (16) and having a pair of coaxial input shafts (11, 111), that is, an outer input shaft and an inner input shaft, respectively, a clutch unit (12) interposed between the gearbox and the crankshaft (14) and having a pair of clutches (13, 113) for permitting the transmission of torque between the crankshaft (14) and the respective gearbox input shaft (11, 111), and a pair of rolling bearings (60, 44), mounted on the gearbox support housing (16) and on the outer gearbox input shaft (111), respectively, for supporting the clutch unit (12) for rotation. The transmission is arranged in a manner such as to prevent the forces for actuating the clutches (13, 113) from acting on the crankshaft (14). <IMAGE>
China's Renewable Marine Energy Based on Big Data

Shao, M. and Wu, Z., 2019. China's renewable marine energy based on big data. In: Guido-Aldana, P.A. and Mulahasan, S. (eds.), Advances in Water Resources and Exploration. Journal of Coastal Research, Special Issue No. 93, pp. 597–600. Coconut Creek (Florida), ISSN 0749-0208.The China is located in the eastern part of the Asian continent and the western part of the Pacific Ocean, which is rich in renewable marine energy with various forms and the common characteristics of sustainability.The problem of environmental pollution is aggravated by the consumption of fossil energy, so people pay more and more attention to the development and utilization of renewable energy.The exploitation and utilization of Marine renewable energy is the inherent requirement of realizing the scientific development concept of our country and the inevitable choice of building an environment-friendly and resource-saving society in the 21st century.At present, all countries attach great importance to the development of marine energy and have formulated sound standards for marine energy development.The development of Marine energy can effectively alleviate the energy crisis and promote the innovation of marine energy technology industry.This paper expounds the current situation of Marine energy standardization and analyzes the specific problems and countermeasures according to the big data.
Japan and europe network for neutrino and intensity frontier experimental research 2

JENNIFER2  is the evolution and development of the research and communication activities currently being carried on by the JENNIFER MSCA-RISE project, which will be concluded at the end of march 2019. The new challenges of fundamental physics require to use different complementary approaches and to design experiments able to test different “messengers” of the new physics world. The JENNIFER2 project  is actually implementing this requirement, putting together research programs at experimental facilities located in Japan including accelerator produced neutrinos (T2K and HyperK collaborations), cosmic neutrinos detection (HyperK collaboration) and a high luminosity electron-positron collider (Belle II experiment at SUPERKEKB) where very rare processes can be observed. The collaboration of European scientists with the Japanese research community is fostered in all experimental issues, while specific knowledge sharing among different experiments is planned in the field of photon detection, computing, real time and remote controls, data analysis algorithms and theory calculations, aiming to build up  real synergies on key technologies and research methodologies, as well as on dissemination and outreach. Such cross-fertilization between different experimental approaches is the crucial step towards an effective multi-messenger approach.
SKIN CLEANSING COMPOSITION AND METHOD OF USE

An aqueous skin cleansing composition, comprises: (I) a cleansing surfactant selected from the group consisting of anionic surfactant, cationic, zwitterionic or amphoteric surfactant and nonionic surfactant; (II) a skin benefit agent, (III) an anti-settling, thickening polymer, wherein the anti-settling, thickening polymer, comprises: (a) 40 to 74.5 wt% of structural units of C1-4 alkyl acrylate; (b) 20 to 50 wt% of structural units of methacrylic acid; (c) 0.2 to < 5 wt% of structural units of 2-acrylamido-2-methylpropane sulfonic acid (AMPS); (d) 5 to 25 wt% of structural units of a specialized associated monomer having the following structure wherein R1 is a linear saturated C10-24 alkyl group; wherein R2 is a hydrogen or a methyl group (preferably, wherein R2 is a methyl group); and wherein n is an average of 20 to 28; with the proviso that the structural units of the specialized associated monomer (d) are derived from one of (i) a single specialized associated monomer (preferably, a single specialized associated monomer wherein R1 is selected from the group consisting of a linear saturated C12 alkyl group, a linear saturated C18 alkyl group and a linear saturated C22 alkyl group; more preferably, a single specialized associated monomer wherein R1 is selected from the group consisting of a linear saturated C12 alkyl group and a linear saturated C18 alkyl group); (ii) two specialized associated monomers, wherein R1 is, respectively, a linear saturated C12 and a linear saturated C18 alkyl group; or (iii) two specialized associated monomers, wherein R1 is, respectively, a linear saturated C18 alkyl group and a linear saturated C22 alkyl group; (e) 0 to 1 wt% of structural units of acrylic acid; and (f) 0 to 2 wt% of structural units of multi-ethylenically unsaturated crosslinking monomer or chain transfer agent; and wherein the sum of the weight percentages of structural units (a)-(f) is equal to 100 wt% of the anti-settling, thickening polymer; and a method of treating skin comprising the step of applying to the skin such a composition.