SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Implementation of the discoveries centre for regenerative and precision medicine, a new centre of excellence in portugal

This proposal is an initiative from 5 top-ranked Portuguese universities including the University of Minho (UMINHO), the University of Porto (UPORTO), the University of Aveiro (UAVR), the University of Lisbon (ULISBOA), the New University of Lisbon (UNL), and a university of research and innovation excellence from the United Kingdom, the University College of London (UCL). These institutions will be the founders of the future independent multi-campi research centre, The Discoveries Centre for Regenerative and Precision Medicine. This partnership is coordinated by the Portuguese Foundation for Science & Technology (FCT). The Discoveries Centre to be created during the proposed project will perform world-leading research, by anchoring research activities of the best research groups in Portugal, promoting excellence, advanced training, translational research outputs and commercialisation strategies. In the long-run, these are expected to generate an important economic impact, as well as a positive social effect by contributing to the increase of the quality of life of an ageing European population affected by neurodegenerative, cardiovascular and musculoskeletal diseases. 
It is anticipated that The Discoveries Centre will be able to foster a knowledge-based economy aligned with national and regional strategic priority areas and European societal challenges, thus reinforcing Portugal’s scientific capabilities, create also critical mass of science in this field of research, as well as social and economic development. It will also contribute to a global recognition of the national scientific production, having a structuring effect in the Portuguese science, generating high value-added products, attracting top-level international scientists, as well as enhancing the capacity to retain the best Portuguese researchers. This proposal has the strongest possible support (financial) from the Portuguese National  Government and the Regional Authorities.
Mandibular bone mineral density in patients with Beh&ccedil;et&rsquo;s disease

Behçet's disease (BD) is a chronic, recurring vasculitis of unknown etiology. Patients with BD may use a lot of medications associated with the clinical symptoms. Drugs that are used in the treatment of BD may cause bone loss. The aims of the current study were to compare the bone mineral density (BMD) values between BD and healthy volunteers and describe the effect of disease duration on mandibular BMD.The study comprised 30 healthy volunteers (15 males and 15 females, mean age 35.50±6.80 years) and 45 patients with BD (24 males and 21 females, mean age 38.93±8.93 years). The BD group was subdivided according to disease duration (0-5, 6-10, and >10 years). The BMD value of the mandibular body was determined by the dual energy X-ray absorptiometry technique.The mean mandibular body BMD values were 1.294±0.21 g/cm(2) in the control group and 1.216±0.22 g/cm(2) in the BD patients, although there was no statistically significant difference. The BMD was observed to decrease with increased disease duration but not to a statistically significant degree.The results of this study showed that although the BMD value decreased as the duration of the disease increased, no statistically significant difference was found between the BD patients and the healthy control group.
Plastic in agricultural production: impacts, lifecycles and long-term sustainability

PAPILLONS will elucidate ecological and socioeconomic sustainability of agricultural plastics (APs) in relation to releases and impacts of micro- and nanoplastics (MNPs) in European soils. We will advance knowledge on sources, behaviour and impacts through cross-disciplinary research, bringing together scientists from chemistry, materials engineering, agronomy, soil ecology, toxicology and social sciences. We will transform the scientific knowledge generated into guidance on specific solutions by applying a Multi-actor approach, involving actors in the agricultural and policy sector and world-leading industries. This will enable co-creation of knowledge and provide the scientific background to enable policy, agricultural and industrial innovation towards sustainable farm production systems.
We will deliver the first digital European atlas of AP use, management and waste production to estimate sources of MNP to agricultural soils. We will run integrative studies at laboratory, mesocosm and field scales in different parts of Europe to address: occurrence of AP-derived MNPs; MNP behaviour and transport in soil; uptake by biota and crops; long-term impacts on soil properties, fertility and ecological services; effects on biological and functional diversity across multiple scales; effects on plant production and quality; and socioeconomic impacts of AP-based practices. We will focus on multigenerational effect studies for relevant traditional and biodegradable polymers, at realistic and future high-exposure scenarios.
PAPILLONS partners pioneered soil MNP research, host the majority of European analytical capacity for assessing soil contamination and will provide validated, high-throughput analysis for MNPs in soil. Using innovative applications of state-of-the-art analytical chemistry, we will advance analysis down to the nanoscale range and develop novel radiolabelled nanoplastics for accurately tracking behaviour and transport in soil and uptake by biota and crops.
News hotspots detection and tracking based on LDA topic model

With the rapid spread of Internet and the mobile web, the number of news pages is increasing quickly as well as the content of news becomes highly dynamic. It's difficult for normal users to obtain specific information contained in a mass of news streams. So it's of great research significance to study how to analyze massive news, detect and track news hotspots automatically. This research proposes to apply LDA (Latent Dirichlet Allocation) model to the application of topic detection and tracking. The news articles collected by crawlers are modeled by the LDA model in a form of document-topic-word distribution. We propose a method to compute the heat of topics based on the distribution and to detect the news hotspots. In addition, we track the evolution of the topic trends in different time-slices. Jenson-Shannon distance is used to measure the similarity between topics to identify topic inheritance and topic mutation. We conducted experiments on a dataset consisting of 3462 news texts from news portals. The result revealed that the proposed model has a good effect both in detecting hotspots and discovering meaningful topical evolution trends.
Supply Chain Visibility: From Theory to Practice

Transparency and accurate management information are essential if you want to ensure that the supply chain is working for your business. Supply Chain Visibility is a critical primer for readers with backgrounds in supply chain management, system integration, strategy consulting, and enterprise software. Jonah McIntire sets the stage for a new framework that empowers business leaders to connect their projects, tasks or work streams back to the strategic message that it is worth applying organizational resources to supply chain visibility. Drawing on research findings, he reviews the prerequisites needed for a successful visibility solution and suggests a visibility fitness scorecard to compare the quality of widely varying approaches. The second section of the book reviews in detail the eight most common types of supply chain visibility and offers a set of indicators of potential fit for each one. The book also explains how to acquire visibility technology and the available options, and includes guidance on best practice for in-house designed systems. If you or your organization are moving into this area, Jonah’s insights will place you in a far stronger position to decide exactly how to leverage the benefits of supply chain visibility solutions; they also walk you carefully through the minefields of ineffective approaches or technologies to give you the greatest chance of success.
Hacia un seguimiento más completo y armonizado de los daños en los bosques: Aplicación a la defoliación arbórea en España

La defoliación arbórea es uno de los mejores indicadores para evaluar el estado fitosanitario de los bosques. Existen varias redes en España que toman esta información: Red Europea de Seguimiento de Daños en Bosques de ICP-Forests, Redes Autonómicas de Seguimiento de Daños, y Red de Seguimiento y Evaluación de Parques Nacionales. El objetivo de este estudio es el análisis de la dinámica de la defoliación en regiones bioclimáticas, tipos de masas y principales especies de coníferas (Abies alba, Pinus uncinata, Pinus sylvestris, Pinus nigra, Pinus halepensis, Pinus pinaster, Pinus pinea) y frondosas (Castanea sativa, Fagus sylvatica, Quercus pyrenaica, Quercus robur, Quercus ilex, Quercus suber, Quercus faginea y Olea europaea) de la España peninsular y Baleares. Se armonizó la información de las diferentes redes de daños en una red integrada compuesta por un total de 2858 parcelas con datos entre 1986 y 2015. Los resultados muestran un incremento en la defoliación general media (12.3% en 1986 a un 25.2% en 2015). En coníferas, Pinus uncinata (región alpina), Pinus pinaster (región atlántica) y Pinus halepensis (región mediterránea), mostraron los valores más altos de defoliación en 2015. En frondosas, los valores más elevados se encontraron en Quercus pyrenaica, Quercus faginea, Quercus robur y Castanea sativa, tanto en la región mediterránea como en la atlántica. Se constata la idoneidad de la armonización e integración de las diferentes redes de daños para hacer un seguimiento a largo plazo del estado sanitario de los bosques. Estos resultados ponen en relieve la importancia de contar con una red actualizada e integrada de la información de daños en los bosques como herramienta para una gestión que garantice su sostenibilidad a largo plazo.
Unlocking self-patterning competence to engineer 3d human spinal cord

Organizers direct formation of the body, releasing morphogens to position tissues and organs. But what organizes the organizers? I aim to harness organizer formation to build self-patterning 3D human spinal cord in vitro.

In developing spinal cord, the floorplate organizer secretes Sonic Hedgehog to direct ventral-dorsal patterning. Prof Tanaka (secondment) discovered how to recapitulate this in vitro: single mouse naïve pluripotent stem cells (PSCs) form neural tube organoids and an early pulse of retinoic acid prompts self-organization of floorplate that drives patterning as in vivo. However, attempts to form cognate human organoids have been unsuccessful. There is a restricted window of competence to initiate floorplate formation, which conventional primed human PSCs are unable to access. 

To overcome this, I will combine microenvironment bioengineering with new naïve human iPSCs (Prof Elvassore, host) to recapitulate and study human development from an earlier stage, gaining access to molecular events that may underpin later fate specification and tissue organization. By mechanistic analysis in mouse organoids, I will reveal how competence is instated, how it is closed, and how to prolong or re-instate competence de novo. This knowledge will guide me in unlocking the competent state for human PSCs in vitro, and has implications for activating spinal cord regeneration in vivo. By use of sophisticated engineering technologies pioneered in the Elvassore group, I will control the micro-environment to guide tissue growth and formation, mimicking natural physiology and ensuring reproducibility. By engineering 3D organized human spinal cord in vitro, this project will bridge basic knowledge of critical and inaccessible stages of human development with future biomedical applications. This interdisciplinary training opportunity will build on my doctoral expertise in PSC identity transitions, setting me apart with a strong independent niche for my future career.
NETWORK NODE AND METHOD FOR DISPLAYING A CODE ON A SCREEN

Method and network node (12, 20) for displaying a code on a screen (14) comprising receiving,from an operator node (10) comprised in the operator network (22), a data stream comprising data and meta data and extracting the data and the meta data from the received data stream. The network node sends the extracted data to be displayed on the screen and stores the meta data. The network node then retrieves a code generated from the stored meta data, when receiving from a pre-configured communication device (16) a request for the code and sends the code to be displayed on the screen.
Educação escolar indígena em Pernambuco

Desde o início do contato entre indígenas e europeus, sobretudo a partir da segunda metade do século XVI, a educação foi usada pelos colonizadores como ferramenta de controle e dominação dos povos nativos. Esse interesse na “instrução” dos indígenas, portanto, não era desinteressado, mas buscava atender a demandas religiosas, agrário-mercantis, bélicas etc., dos próprios colonizadores. A partir, sobretudo, dos anos 1980, esse modo de o Estado se relacionar com os povos indígenas é colocado em questão, deslocando os paradigmas de controle, assimilação e integração para paradigmas interculturais. O presente artigo versa sobre essas mudanças no contexto de Pernambuco, a partir das mobilizações dos povos indígenas para a efetivação de uma educação escolar indígena específica, diferenciada e intercultural.
Source and progression of a submarine landslide and tsunami: The 1964 Great Alaska earthquake at Valdez

Like many subduction zone earthquakes, the deadliest aspects of the 1964 M = 9.2 Alaska earthquake were the tsunamis it caused. The worst of these were generated by local submarine landslides induced by the earthquake. These caused high runups, engulfing several coastal towns in Prince William Sound. In this paper, we study one of these cases in detail, the Port Valdez submarine landslide and tsunami. We combine eyewitness reports, preserved film, and careful posttsunami surveys with new geophysical data to inform numerical models for landslide tsunami generation. We review the series of events as recorded at Valdez old town and then determine the corresponding subsurface events that led to the tsunami. We build digital elevation models of part of the pretsunami and posttsunami fjord-head delta. Comparing them reveals a ~1500 m long region that receded 150 m to the east, which we interpret as the primary delta landslide source. Multibeam imagery and high-resolution seismic reflection data identify a ~400 m wide chute with hummocky deposits at its terminus, which may define the primary slide path. Using these elements we run hydrodynamic models of the landslide-driven tsunamis that match observations of current direction, maximum inundation, and wave height at Valdez old town. We speculate that failure conditions at the delta front may have been influenced by manmade changes in drainage patterns as well as the fast retreat of Valdez and other glaciers during the past century.
Epidemiological analysis of eosinophilia and elevation of immunoglobulin E as a predictable and relative risk of enteroparasitosis.

among the intestinal parasites, the helminthiasis occupies a prominent position in Brazil, since it worsens malnutrition and the gives rise to neurovegetative disorders. Helminths like Ascaris lumbricoides, Enterobius vermicularis, hookworm, Trichuris trichiura and Strongyloides stercoralis stand out due to several factors that modulate the immune response of individuals. Among the protozoa are Giardia lamblia, Entamoeba histolytica. E. dispar. Parasitic helminth antigens are important to stimulate the production of cytokines such as interleukin-4 and interleukin-5, which act through the induction of IgE synthesis and activation of eosinophils. Eosinophilia is usually detectable in pre-patent period of parasitism, initially linked to B lymphocytes, under the command of Th-2 lymphokines (IL-4 and IL-5), producing IgE in response to initial exposure to an antigen or allergen. Serum IgE high levels occur in tissue migration of larvae or harboring of parasites in tissues.to determine the presence of eosinophils and IgE elevation in children with intestinal parasites.high levels of IgE and eosinophils were observed in groups infected and not infected (allergic) to calculate the relative risk of intestinal parasites presumptive differentiated between protozoa and helminths and check what values of these indicators are observed in the epidemiological profile of the surveyed population.the values obtained by calculating the relative risk for eosinophilia, compared with helminths and allergies was 11.71, but when examined by giardiasis compared with other diseases, the relative risk was 0.75. Since the comparison of helminths and giradiase, the relative risk was 27.33. Since IgE and its parameters were appropriate commit Helminth relative risk 0.39; Giardiasis had relative risk 8, 18 and Helminths compared with giardiasis had 0.03.in this study it was possible to observe that helminthiasis is connected with cases of eosinophilia with alteration of IgE, which in turn contributes to the presence of IgE eosionofilia and has an effector response against helminths that provides the expulsion of its larvae.
The physics of galaxies 7 gyr ago

Over the past decade, redshift
surveys and multi-wavelength imaging campaigns have drawn up an
empirical picture of how many stars had formed in which types of
galaxies over the history of the universe.  However, we have yet to
unravel the individual pathways along which galaxies evolve, and the
physical processes that drive them.  Continuing with the previous
approach -- larger and deeper photometric samples -- is not adequate
to achieve this goal.  A change of focus is required.

In this ERC project I will embark on a new way to address the question
of galaxy evolution.  I will do so as Principle Investigator of the
recently approved LEGA-C observing program that has been allocated 128
nights of observation time over the next 4 years with ESO's flagship
facility the Very Large Telescope.  This new survey will produce for
2500 distant (at z~1) galaxies with, for the first time,
sufficient resolution and S/N to measure ages and chemical
compositions of their stellar populations as well as internal velocity
dispersions and dynamical masses.  This will provide an entirely new
physical description of the galaxy population 7 Gyr ago, with which I
will finally be able solve long-standing questions in galaxy formation
that were out of reach before: what is the star-formation history of
individual galaxies, why and how is star-formation ``quenched'' in
many galaxies, and to what extent do galaxies grow subsequently
through merging afterward?

LEGA-C is worldwide the largest spectroscopic survey of distant
galaxies to date, and ERC funding will be absolutely critical in
harvesting this unparallelled database.  I am seeking to extend my
research group to realize the scientific potential of this substantial
investment (6.5M Eur) of observational resources by the European
astronomy community.  Timing of the execution of the VLT program is
perfectly matched with the timeline of this ERC program.
Credibility models with risks dependence structure under LINEX loss function

In classical credibility theory,the actuary uses squared-error loss function to estimate premium,but it can lead to very high penalties which affects the competitive strength of insurance market.On the other hand,classical credibility theory assumes that the claim amounts of every insurance policy in a portfolio are independent,however,the claim amounts of every insurance policy are risks dependent.Wen et al.(2012)studied the credibility model with time changeable effects among the claim amounts of one insurance policy and obtained credibility premium,this risks dependence structure was generalized to the claim amounts of every insurance policy.The Buhlmann-Straub model was considered with risks dependence structure among every insurance policy under LINEX loss function and the credibility premium formula which generalized the classical credibility model is obtained.
A Grounded Theory of Decision-Making Under Uncertainty and Complexity

The researcher looked for how decision-makers make meaning to produce decisions, how they structure a network of people that can help to understand what?s the best under the uncertain context. This process is Learning under Uncertainty which is interpreted as being a process of learning through experience and sensing others? needs. The methodology selected was a combination of: Grounded Theory Methodology and Actor-network Theory. The data was gathered and analysed from interview participants from different fields. This book makes a number of contributions to the field of decision-making,analysing it through the perspective of being based on interactional constructs in a social-context web,where information system views are present, but are also enhanced with human constructs that come through human activity systems. This book provides three results in the form of frameworks, respectively a GTM conceptual framework (situational framework), a conceptual ANT network (process framework) and an enhancement conceptual framework (behavioural framework). This book, aimed at students and researchers in decision science, DSS and information management in general.
Point: ip over icn - the better ip

The goal of POINT is to develop technology, innovations, and business value chains for commercially viable IP-over-ICN deployment, based on the hypothesis that many current IP-based applications can run ‘better’ on an ICN-based network than on current IP networks.

To achieve this, we will first define a set of Key Performance Indicators (KPIs) to specify what exactly 'better' means. Then, we will specify a communication platform based on the ICN prototype developed in FP7 PURSUIT and develop a set of abstractions to enable current IP, TCP, HTTP and CoAP based applications to run on our platform, complemented by new resource coordination mechanisms to improve the performance of the network.

We will implement our platform as an operational prototype and validate it against the KPIs in a testbed as well as run a real-world field trial in an operator's production network with real customers. We will openly publish our design and all relevant data needed to deploy and improve our prototype, which in turn will be released as open source code. We will also undertake a wide range of dissemination activities to establish POINT as a key driver in the ICN community.

The POINT platform will provide new business opportunities for systems vendors, operators and service providers, including SMEs and we will evaluate the commercial viability of our solution and develop migration scenarios for operators wishing to deploy ICN in production networks. The consortium has all the experience and competencies needed to cover the entire chain from an idea and research prototype to a working platform ready for production use. In addition to academic partners, POINT includes a technology company, a telecom vendor, an ISP, a content provider, and a cooperative which will enable POINT to have an impact on the industry.