SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
[Clinical-epidemiological profile of patients with thyrotoxic periodic paralysis in two peruvian hospitals].

Thyrotoxic Periodic Paralysis (PPT) is an uncommon complication of hyperthyroidism, it is the most frequent cause of acute flaccid paralysis in adults.A retrospective observational study was carried out in 2 reference hospitals of the social security in Lima-Peru, which included 22 patients diagnosed with PPT during the period 2014-2021.the average age at diagnosis was 35.77 ± 9.6 years, all of mixed race, in 82% of the patients the diagnosis of hyperthyroidism was established from this entity, the etiology in 95% was autoimmune (Graves-Basedow) except for one whose etiology was toxic multinodular goiter. The triggering event reported in 54% of patients was the intake of copious food high in carbohydrates, followed by exercise (27%), the most frequent presentation time was during the morning (41% of the cases), the main weakness pattern compromised lower limbs (45% paraplegia, 18% paraparesis), only 36% were diagnosed with PPT in their first episode of motor weakness.We consider that this condition should be suspected in any young male patient of any ethnicity with acute muscle weakness, associated with low serum potassium levels and symptoms of thyrotoxicosis, although its absence should not rule out the diagnosis. The precipitating factor should be identified as much as possible and initial therapy with propanolol with or without intravenous or oral potassium replacement should be established, with adequate subsequent monitoring to minimize the risk of rebound hyperkalemia.la paralisis periodica tirotóxica (PPT) es una complicación poco común del hipertiroidismo, corresponde la causa más frecuente de parálisis aguda flácida del adulto.se realizó un estudio observacional retrospectivo en 2 hospitales referenciales del seguro social en Lima-Perú, que incluyo a 22 pacientes (21 hombres, 1 mujer) diagnosticados con PPT durante el periodo 2014-2021.la edad promedio al diagnóstico fue de 35.77 ± 9.6 años, todos de raza mestiza, en 82% de los pacientes el diagnostico de hipertiroidismo fue establecido a partir de esta entidad, la etiología en el 95% fue autoinmune (enfermedad de Graves-Basedow) excepto uno cuya etiología fue bocio multinodular tóxico. El evento desencadenante reportado en 54% de pacientes fue la ingesta de comida copiosa alta en carbohidratos, seguido del ejercicio (27%), el horario más frecuente de presentación fue durante la mañana ( 41% de los casos), el patrón de debilidad principal comprometió miembros inferiores(45% paraplejia, 18% paraparesia), solo 36% fue diagnosticado de PPT en su primer episodio de debilidad motora.consideramos que se debe sospechar esta condición en cualquier paciente varón joven de cualquier etnia con debilidad muscular aguda, asociado a niveles séricos bajos de potasio y síntomas de tirotoxicosis, aunque su ausencia no debe descartar el diagnostico. Se debe identificar en lo posible el factor precipitante e instaurar terapia inicial con propanolol con o sin reemplazo de potasio endovenoso u oral, con monitoreo posterior adecuado que minimice el riesgo de hiperpotasemia de rebote.
ALPINE NETWORK FOR SHEEP AND GOAT PROMOTION FOR A SUSTAINABLE TERRITORY DEVELOPMENT

A network among Alpine shepherds’ Associations, regional administrations,research institutions, will organise common, trans-national and coordinated activities to promote and to preserve sheep and goat sector, its social involvement and its capacity to participate in the sustainable spatial development. Main activities are: data collection on spreading  and asset of breeding activities, on the existing genetic heritage; inventory and evaluation of the areas suitable for grazing;  development of regional and trans-regional strategies; implementation of a trans-national monitoring system for breeds; exchange of experiences and best practices; participation at international exhibitions; publication of manuals enhancing the contribution of pastoralism to environment; promotion of the shepherds social value and their integration within tourism and handicraft; training activities on marketing  and e-commerce aimed to improve the competitiveness of sheep and goat products.
Espèces de diatomées saumâtres observées à la source bitumineuse du Puy de la Poix : un îlot de curiosité

La source de la Poix est une particularité géologique du Massif central français car elle est connue pour être bitumineuse associée à de l’eau salée, du méthane et des traces d’hydrogène sulfuré. Entre mars 2017 et juin 2020, trois prélèvements ont été effectués en raclant les diatomées sur la couche de bitume. De plus, les conditions physiques et chimiques ont été examinées. Il apparaît que la conductivité de l’eau salée est supérieure à celle de l’océan, entraînant le développement de certaines espèces de diatomées saumâtres, observées pour certaines d’entre elles sur les sédiments intertidaux ou dans les estuaires. Même si les conditions abiotiques étaient extrêmes pour ces algues, la biodiversité était élevée et révèle des espèces ayant une grande capacité à supporter des concentrations et des fluctuations de salinité élevées.
Scaling up behavior and autonomous adaptation for macro models of climate change damage assessment

Damage associated with climate change is a core benchmark in science and policy. Macro Integrated Assessment Models estimating damages are criticized for neglecting risk distribution, adaptation dynamics and the possible collapse of regional economies. Micro-level social science studies contain substantial knowledge on individual behavior, decisions under risk and autonomous climate adaptation, and go beyond monetary losses by focusing on resilience. This knowledge can ameliorate theoretical and empirical flaws in current macro assessments, if adequate scaling up methods were to exist. 
SCALAR aims to bridge the gap between micro and macro research traditions by modeling the behavioral aspects of autonomous adaptation processes of heterogeneous agents, and integrating them into macro level climate policy models. The project focuses on floods. Its innovative nature allows to revisit the classic micro-macro aggregation problem through a unique combination of:
1) New behavioral data on climate adaptation decisions collected in multiple survey waves using mobile applications, going beyond a snapshot to uncover evolving decision processes;
2) Advances in agent-based modeling to scale up adaptation decisions of heterogeneous households and firms to a regional economy while including land use and hazard data;
3) Cutting-edge ways of integrating micro-simulation models with traditional macro models to synergize the two approaches for developing new theory- and data-grounded macro damage assessments.
SCALAR will drive a major breakthrough in integrating behavioral aspects of human decision-making into macro climate policy models. It will enable the quantitative exploration of cross-scale damage cascades, the identification of thresholds over which autonomous adaptation impacts the macro level, and the tracing of the emergence of socio-economic resilience as climate change unfolds. The methodological advancements will have impact far beyond the domain of climate adaptation.
A novel solution for aircraft washing and de-icing

Runway Star RS-500 is a fully automated dual-use aircraft de-icing and washing facility designed to address two significant industry problems. First, de-icing of aircraft is a safety-critical yet costly process. It relies on skilled operators manually applying up to 5000 litres of de-icer, which is both wasteful and environmentally damaging.. RS-500 will reduce de-icing fluid use, eliminate wind-borne losses and improve airport efficiency by reducing washing and de-icing cycle times. It lowers costs, recovers up to 95% of excess fluid and provides full audit trails.

The second industry problem relates to the current inability of airline operators to cost-effectively clean aircraft. Currently, washing coincides with infrequent aircraft servicing. Dirty aircraft consume1-2% more fuel due to increased aerodynamic drag. RS-500 will integrate efficient, automated washing within its de-icing facility, allowing airlines to increase wash frequency, reducing fuel consumption.

With a payback of less than 18 months, RS-500 is an attractive investment for stakeholders and the system has generated overwhelming interest from airport owners, aircraft operators, and ground handlers. Scale model demonstrations and de-icing trials have been completed with excellent results. The system provides a new approach to washing and de-icing operations and MSG have recently applied for patent coverage in Europe, the US and Canada. 

The project has already received significant offers of support, engineering expertise and components for the control system. Customers are waiting - a state airport operator has already indicated their interest in purchasing 4-8 systems, subject to successful demonstration activities. Horizon 2020 financial support is essential to enable MSG Production to demonstrate the system and exploit significant market opportunities.
SEPARATION OF CARBON NANOTUBES IN DENSITY GRADIENTS

The separation of single-walled carbon nanotubes (SWNTs), by chirality and/or diameter, using centrifugation of compositions of SWNTs in and surface active components in density gradient media.
A meta-analysis of cognitive deficits in first-episode Major Depressive Disorder

Recurrent-episode Major Depressive Disorder (MDD) is associated with a number of neuropsychological deficits. To date, less is known about whether these are present in the first-episode. The current aim was to systematically evaluate the literature on first-episode MDD to determine whether cognition may be a feasible target for early identification and intervention.Electronic database searches were conducted to examine neuropsychological studies in adults (mean age greater than 18 years old) with a first-episode of MDD. Effect sizes were pooled by cognitive domain. Using meta-regression techniques, demographic and clinical factors potentially influencing heterogeneity of neuropsychological outcome were also investigated.The 15 independent samples reviewed yielded data for 644 patients with a mean age of 39.36 years (SD=10.21). Significant cognitive deficits were identified (small to medium effect sizes) for psychomotor speed, attention, visual learning and memory, and all aspects of executive functioning. Symptom remission, inpatient status, antidepressant use, age and educational attainment, each significantly contributed to heterogeneity in effect sizes in at least one cognitive domain.Reviewed studies were limited by small sample sizes and often did not report important demographic and clinical characteristics of patients.The current meta-analysis was the first to systematically demonstrate reduced neuropsychological functioning in first-episode MDD. Psychomotor speed and memory functioning were associated with clinical state, whereas attention and executive functioning were more likely trait-markers. Demographic factors were also associated with heterogeneity across studies. Overall, cognitive deficits appear to be feasible early markers and targets for early intervention in MDD.
Improving attributional life cycle assessment for decision support: The case of local food in sustainable design

Abstract Life cycle assessment (LCA) has become widely used to evaluate the environmental sustainability of products. It has been increasingly realized, however, that the conventional framework, attributional LCA (ALCA), may be inadequate for steering decision making. Here we show how ALCA can be improved for decision support if we recognize its limitations. Using local food production in the U.S. as a case study, we show that ALCA can be enhanced by relaxing some of the restrictive assumptions (e.g., static, aggregate, site-generic, linear), by evaluating the situation in question from a more dynamic and prospective angle, and by accounting for the important role of decision makers to introduce innovative systems that reshape the status quo. For local food, studies of food miles have shown that transportation is a minor source of carbon emission, with an implication that local food is not an effective means of helping the environment. But these studies fail to realize other potential benefits which food localization may uniquely enable including recycling of energy, water, and nutrients. These benefits cannot be derived from a simple presentation of the status quo as often done in ALCA studies. Our results show that for some crops, irrigation could contribute up to 50% of the cradle-to-gate carbon emissions, thus they may benefit from food localization making use of water from wastewater treatment plants. Our results also show that local food could reduce the water footprint of lettuce by 50%. Our study suggests that exploring future scenarios, beyond assessing historical outcomes, is critical if ALCA is to support sustainable decision making.
Development of Financial Ecosystems for the Promotion of Social Entrepreneurship in Rural Regions

European rural regions are currently facing several societal challenges, especially aging of population, brain drain and unemployment. Social innovation becomes more important to develop solutions to these problems and the promotion of social entrepreneurship (SE) is an important contribution to facilitate the economic transformation process especially in rural areas. Nevertheless, the traditional business support infrastructures and measures operated by regional or local authorities are not adapted to the special needs of social enterprises. There is a general lack of knowledge and understanding how social entrepreneurship evolves and works and how it can be efficiently promoted.
The main objective of the project is the promotion of social entrepreneurship in rural regions with special transformation challenges to advance economic and social innovation. The rural regions Saalekreis (DE), Hajdu Bihar (HU), Duga Resa (CR) and rural areas in Piedmont Region (IT) work together with the specific objective to improve funding for public support structures for social entrepreneurship and further develop finance and funding instruments for social enterprises. The project wants to facilitate a quadruple helix cooperation process of regional and local stakeholders for social entrepreneurship in a rural environment.
The partners will develop a toolbox for promotion of social entrepreneurship in rural regions, which will be tested in four pilot projects. 8 capacity building seminars with focus on municipalities and finance institutions will be organised to further spread the developed knowledge. Finally, 4 actions plans will be developed in the partner regions to ensure sustainability and mainstreaming of project results. The project will allow a transnational mutual learning process of partners with similar challenges and different experiences. The transfer and adaptation of experiences for promotion of social entrepreneurship in a rural environment is innovative.
Gender Differences in the Temporal Sequencing of Problem Gambling with Other Disorders

Gender differences in the temporal sequencing of problem gambling and other disorders was investigated in a sample of 267 gamblers, recruited from treatment centres. There were 144 men (54 %) with a mean age of 40.58 years and 123 women with a mean age of 48.72 years. All participants completed a survey assessing age of first onset for problem gambling and age of first onset for mood and substance abuse disorders. Results revealed that women tended to experience other disorders before the first onset of problem gambling, whereas men tended to experience other disorders after the first onset of problem gambling. Data are also provided showing the mean number of years between the initial episode of problem gambling and other disorders. Results are discussed in relation to treatment implications and the limitations of retrospective data.
Avantis structural rod adjustment system

The aim of the project is to design, define, realize and test one prototype of adjustable length structural rods that can withstand high loads encountered in the aeronautical field.
Two overall concepts will be studied and one of them will be retained for the prototype.
First solution consist to reinforce existing adjustable rods locally by welding titanium threaded inserts in order to support high loads and avoid fatigue problems.
The second solution consists to invent a welded assembly method and the associated tool in order to complete the manufacture of rods on the aircraft during integration phase.
During this project, the AVANTIS Company, specialized in innovative aeronautical design and ARMINES laboratory will take the required measures to evolve from first ideas to the final demonstrator and to upgrade the technology readiness level (TRL) from 2 to 4.
DENTAL SURGICAL MEDICAL STUDY 2.0 — REPOSITIONING OF PROFESSIONAL ACTIVITIES THROUGH TECHNOLOGICAL INVESTMENTS

THE PROPOSED INVESTMENT PRESENTS AN INTERESTING ANALOGY AND CORRESPONDENCE WITH THE REQUIREMENTS AND OBJECTIVES OF INDUSTRY 4.0 WHICH HAS AS THE HEART OF THE WHOLE SYSTEM THE CONCEPT OF THE INTERCONNECTION OF THE MACHINES TO THE MANAGEMENT SYSTEM OF THE PROFES ACTIVITY
Fisher information and criticality in the Kuramoto model of nonidentical oscillators

We use the Fisher information to provide a lens on the transition to synchronization of the Kuramoto model of nonidentical frequencies on a variety of undirected graphs. We numerically solve the equations of motion for a N=400 complete graph and N=1000 small-world, scale-free, uniform random, and random regular graphs. For large but finite graphs of small average diameter the Fisher information F as a function of coupling shows a peak closely coinciding with the critical point as determined by Kuramoto's order parameter or synchronization measure r. However, for graphs of larger average diameter the position of the peak in F differs from the critical point determined by estimates of r. On the one hand, this is a finite-size effect even at N=1000; however, we show across a range of topologies that the Fisher information peak points to a transition for smaller graphs that indicates structural changes in the numbers of locally phase-synchronized clusters, often directly from metastable to stable frequency synchronization. Solving explicitly for a two-cluster ansatz subject to Gaussian noise shows that the Fisher infomation peaks at such a transition. We discuss the implications for Fisher information as an indicator for edge-of-chaos phenomena in finite-coupled oscillator systems.
Omics and Drug Response

A new generation of technologies commonly named omics permits assessment of the entirety of the components of biological systems and produces an explosion of data and a major shift in our concepts of disease. These technologies will likely shape the future of health care. One aspect of these advances is that the data generated document the uniqueness of each human being in regard to disease risk and treatment response. These developments have reemphasized the concept of personalized medicine. Here we review the impact of omics technologies on one key aspect of personalized medicine: the individual drug response. We describe how knowledge of different omics may affect treatment decisions, namely drug choice and drug dose, and how it can be used to improve clinical outcomes.
The effect of dietary Jerusalem artichoke (Helianthus tuberosus L.) on performance, egg quality characteristics and egg cholesterol content in laying hens

This research was carried out to determine the effect of Jerusalem artichoke (JA) with or without 5, 10% vetch (V) supplementation on performance, egg quality characteristics and egg cholesterol content. In the study, seventy-five 25 weeks-old commercial white laying hens were randomly divided into one control and 4 treatment groups each containing 15 hens. Control group was fed basal diet without JA or V. Treatment group 1, 2, 3 and 4 were fed diets containing 5% V, 5% JA, 5% JA + 5% V and 10% JA + 10% V, respectively. The feeding period lasted 16 weeks. In the study, it was determined that dried-ground JA contained dry matter, crude protein, ether extract, crude fibre, crude ash, inulin and metabolizable energy (ME) at the level of 93.30, 10.02, 0.36, 5.64, 9.05, 15.80% and 3 060 kcal/kg, respectively. At the end of the study, live weight was lower by 4.36&amp;ndash;10.09% in the treatment group 10% JA + 10% V compared with the other groups, but feed efficiency was improved in this group. There were statistically significant differences between the groups in egg quality characteristics (P &amp;lt; 0.05, P &amp;lt; 0.001). Egg production was not affected by supplementation of 5, 10% JA with or without 5, 10% V supplementation. Egg yolk cholesterol and total cholesterol content were not different in the groups (P &amp;gt; 0.05). As a result, the addition of JA with or without V has no adverse effect on performance and egg quality in hens. &amp;nbsp;
Evaluation on Features of Soft Foundation Engineering and Bearing Layer of Pile in Jiaxing City

Through the investigation into composition of major shallow foundation soil mass and the correlation of mechanical indicators in this study, the regression equation of mechanical indicators of the features of local foundation soil mass and the data of in situ testing was obtained. Based on massive quantities of exploration materials, this study analyzed engineering features, distribution status, and the feasibility of silty clay to be used as the bearing layer of the pile in Layer ④ 2 . The analytical results showed that the silty clay with the uniform depth of over 3.5m and the cone tip resistance in static sounding of over 400MPa could be used as bearing layer of the pile. This study could provide the reference for the accurate understanding of the engineering features of soil mass, and the design and evaluation of foundation in Jiaxing City.
CLOSURE ESPECIALLY FOR RECEIVING OR CLAMPING A FOLDED PART OF A BAG

Closure made of plate material comprising a first closing part (1) provided with an opening (1a) cut through the material of the closure. The closure comprises a second closing part (2) movable with respect to the first closing part (1), whereby an edge part (3a) of the opening (1a) of the first closing part (1) in co-operation with an edge part (3b) of the second closing part (2) may enclose a hole (3). The closure further comprises connection means (4, 5 or 6) for the transferral of force between the two said closing parts (1 and 2).
Molecular mechanisms controlling exit from mitosis

Cancer, the uncontrolled division and spread of cells, represents one of the most important causes of death in Europe and all over the world. Understanding how cells control their division is the key to comprehend and cure cancer. Eukaryotic cells divide through mitosis to produce new cells with identical DNA. Yet, mitosis has to be ended for the two cells to be separated to become individual cells with the capacity to further divide. This occurs by a process called mitotic exit. Mitotic exit is a critical step during cell division. Failure to control mitotic exit is the key cause of aneuploidy and genomic instability, which are hallmarks of cancer. Therefore, gaining a comprehensive knowledge of mitotic exit regulation will have significant impact on understanding and treatment of cancer. In this project, the researcher will uncover a novel mechanism that control exit from mitosis mitotic. This novel regulation has the potential to define a molecular target to fight cancer in long term. Researchers previous research experience puts her in a unique position to perform this project. This fellowship will also allow the researcher to build a successful academic career, to acquire new expertise and soft skills, and to establish future collaborations through dissemination, communication and training.  Furthermore with this fellowship, researcher will help increase public awareness of science through outreach activities.