SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
The relationship between depression and frailty syndrome: a systematic review

Frailty is a geriatric syndrome characterised by the clinical presentation of identifiable physical alterations such as loss of muscle mass and strength, energy and exercise tolerance, and decreased physiological reserve. Frailty and depressive symptoms are common issues facing older adults and may be associated. It is not clear if the depression facilitates the appearance of frailty syndrome or vice versa or these two coexist independently in the same individuals.We performed searches in several databases (Embase, PubMed, CINAHL, Scopus, and PsycINFO) papers published between November 2003 to February 2014 about frailty syndrome and depression in people aged 65 and older published and the reference lists of from the articles retrieved were pearled in order to identify any which may have been missed in the initial search. Two independent reviewers extracted descriptive information on the prevalence and co-occurrence of frailty and depression in older individuals and of frailty criteria among depressed patients.Depression and frailty occur in a significant proportion of frail older individuals. Common pathophysiological alterations and biomarkers in the two syndromes have been recently described.Studies on the causal relationship between the two syndromes are clearly necessary in the future.
Risks to health among American Indian/Alaska Native high school students in the United States.

According to the World Health Organization, the 10 leading risk factor causes of death in high-income countries are tobacco use, high blood pressure, overweight and obesity, physical inactivity, high blood glucose, high cholesterol, low fruit and vegetable intake, urban air pollution, alcohol use, and occupational risks. We examined the prevalence of some of the leading risks to health among nationally representative samples of American Indian/Alaska Native (AI/AN) high school students and compared rates across racial/ethnic groups.We combined data from the 2001, 2003, 2005, 2007, and 2009 national Youth Risk Behavior Survey. The survey is a biennial, self-administered, school-based survey of 9th- through 12th-grade students in the United States. Overall response rates for the surveys ranged from 63% to 72%. Of 73,183 participants, 952 were AI/AN students.For 7 of the 16 variables examined in this study, the prevalence among AI/AN high school students was higher than the prevalence among white high school students. For 1 variable (ate fruit and vegetables <5 times per day), the prevalence among AI/AN students was significantly lower than that among white students. The prevalence for the remaining 8 variables was similar among AI/AN students and white students. These findings also show differences in the prevalence of some behaviors among AI/AN, black, and Hispanic students.These findings show the prevalence of some health risk behaviors was significantly higher among AI/AN high school students than among high school students in other racial/ethnic groups.
SEMICONDUCTOR DEVICE AND METHOD FOR MANUFACTURING THE SAME

A semiconductor device and a method for manufacturing the same substantially prevent the degradation of the reliability and characteristics due to hot carriers by using a high-k dielectric material as a gate sidewall spacer material of a gate structure.
The molecular mechanism of mammalian NO-synthases: A story of electrons and protons

Since its discovery, nitric oxide synthase (NOS), the enzyme responsible for NO biosynthesis in mammals, has been the subject of extensive investigations regarding its catalytic and molecular mechanisms. These studies reveal the high degree of sophistication of NOS functioning and regulation. However, the precise description of the NOS molecular mechanism and in particular of the oxygen activation chemistry is still lacking. The reaction intermediates implicated in NOS catalysis continue to elude identification and the current working paradigm is increasingly contested. Consequently, the last three years has seen the emergence of several competing models. All these models propose the same global reaction scheme consisting of two successive oxidation reactions but they diverge in the details of their reaction sequence. The major discrepancies concern the number, source and characteristics of proton and electron transfer processes. As a result each model proposes distinct reaction pathways with different implied oxidative species. This review aims to examine the different experimental evidence concerning NOS proton and electron transfer events and the role played by the substrates and cofactors in these processes. The resulting discussion should provide a comparative picture of all potential models for the NOS molecular mechanism.
A Meta-Analysis of Internal Mammary Lymph Node Metastasis in Breast Cancer Patients

&lt;b&gt;&lt;i&gt;Background: &lt;/i&gt;&lt;/b&gt;Knowing the status of the internal mammary lymph (IML) nodes is important for accurate staging and appropriate selection of subsequent treatment in breast cancer. We conducted a meta-analysis to clarify the rate of IML node metastasis in breast cancer patients and discussed the importance of this finding. &lt;b&gt;&lt;i&gt;Methods: &lt;/i&gt;&lt;/b&gt;We retrieved articles from the literature that reported positive rates of IML node metastasis in breast cancer patients. The quality of the selected articles was assessed using the ‘Methodological Index for Non-Randomized Studies'. The heterogeneity was tested, and publication bias was assessed using a funnel plot. Finally, the positive rate of IML node metastasis in breast cancer patients was calculated using the random-effects model. &lt;b&gt;&lt;i&gt;Results: &lt;/i&gt;&lt;/b&gt;15 articles met the inclusion criteria and a total of 4,248 patients were included in the analysis. Heterogeneity across the studies was statistically significant (p = 0.014); thus, the random-effects model was used and the calculated positive rate of IML node metastasis was 23% (95% confidence interval (CI), 0.21-0.25). &lt;b&gt;&lt;i&gt;Conclusions: &lt;/i&gt;&lt;/b&gt;Approximately 23% of the breast cancer patients had IML node metastases, for which the prognosis is generally poor. Accurate staging and integrated treatment are necessary to improve the survival of these patients.
Self-Disinfecting photodynamic catheters to prevent nosocomial infections

Catheter-associated urinary infections (CAUTIs) are among the most common nosocomial infections, leading to substantial morbidity and mortality. They prolong hospital stays and significantly increase the economic cost of the disease. Despite the many techniques that have been developed to prevent them, spanning from the training of health professionals to the intraluminal use of antibiotics or ""classical"" microbicide coatings, the problem is still largely unsolved. A smart strategy to address the problem would be the development of a universal microbicide coating that only exercises its effect on the indwelling catheter when activated with visible light travelling through the catheter itself, the latter playing as a hollow optical fibre if made of transparent polymer. In this context, we aim to prepare self-disinfecting photoactive (urinary) catheters using the advanced components that modern chemistry and technology provide us, namely, (i) low-power super-bright cheap LEDs and laser diodes, (ii) highly transparent biocompatible polymers (silicones), (iii) versatile surface functionalisation techniques (plasma, silanisation) and (iv) tailored photosensitising dyes capable of generating large amounts of singlet oxygen upon illumination. This reactive oxygen species leads to the destruction of the microorganisms and, therefore, the incipient biofilm (antimicrobial photodynamic inactivation, aPDI), leaving unharmed any cell not contacting the catheter. The combination of the researcher knowledge (photochemistry, dye derivatisation and photodynamic effect), and some of the strongest areas of expertise within the host groups and collaborators (applied photonics, silicones and microbiology), provides all the necessary tools to tackle this challenging interdisciplinary proposal. The project success will benefit both the researchers involved and the entire society, as it contributes to overcome the problem of CAUTIs occurring in hospitals and long-term care facilities.
SECURITY ELEMENT WITH A COLOR-SHIFT EFFECT

The invention relates to a security element for security papers, valuable documents and the like, comprising a thin-layer element (25) with a color-shift effect, said element being made of a reflecting layer (24), an absorbing layer (28) and an intermediate layer (26), arranged between the reflecting layer (24) and the absorbing layer (28). According to said invention, the intermediate layer (26) is formed by a printed layer, the thickness of which can be modified in a locally irreversible manner, after printing, by exposure to external influences, in particular extension, electromagnetic radiation, electron-beam treatment or pressure and/or temperature.
SYSTEM AND METHOD OF COATING PRINT MEDIA IN AN INKJET PRINTER

A coating apparatus for applying a coating liquid to a printing substrate. The coating apparatus has a rotatable first roll (54) and a rotatable second roll (58), each having a surface energy. The second roll is positioned adjacent to the first roll and defines with the first roll a first nip through which the printing substrate passes. A metering device (70) is provided for applying a substantially uniform layer of coating liquid onto the second roll. The second roll in turn transfers the coating liquid to the printing substrate. The surface energy of the second roll is greater than the surface energy of the coating liquid. In one embodiment, the metering device includes a rotatable third roll (72) and a doctor blade (78) contacting the third roll, each having a surface energy. The surface energy of at least a portion of either or both the third roll and doctor blade is less than the surface energy of the coating liquid.
Late Saalian and Eemian Interglacial at the Struga site (Garwolin Plain, central Poland)

Abstract The paper reports pollen analyses of 47 samples from palaeolake sediments at WH-15 Struga near Puznówka on the Garwolin Plain in central Poland. The pollen succession covers Late Saalian (MIS-6) and fully developed Eemian (MIS-5e) successions. The Late Saalian section is well developed (more than 2 m thick) and contains sub-zones reflecting the alternating dominance of steppe-tundra and boreal forest communities. The analysed Eemian succession is an uncommon succession described as a variant with early appearance and culmination of Tilia . In these terms, the successions of WH-15 Struga resemble those of sites of the Eemian interglacial known from the vicinity of Warsaw: Błonie, Warszawa-Żoliborz and Warszawa-Wola. The WH-15 Struga site is one of several recently discovered fossil sites of Eemian lakes on the Garwolin Plain, constituting the southern fragment of the extensive Eemian lakeland in the Polish Lowland.
Cortical sulcal areas in baboons (Papio hamadryas spp.) with generalized interictal epileptic discharges on scalp EEG

Brain MRI studies in people with idiopathic generalized epilepsies demonstrate regional morphometric differences, though variable in magnitude and location. As the baboon provides an excellent electroclinical and neuroimaging model for photosensitive generalized epilepsy in humans, this study evaluated MRI volumetric and morphometric differences between baboons with interictal epileptic discharges (IEDs) on scalp EEG and baboons with normal EEG studies. Seventy-seven baboons underwent high-resolution brain MRI and scalp EEG studies. The scans were acquired using an 8-channel primate head coil (Siemens TRIO 3T scanner, Erlangen, Germany). After spatial normalization, sulcal measurements were obtained by object-based-morphology methods. One-hour scalp EEG studies were performed in animals sedated with ketamine. Thirty-eight (22F/16M) baboons had normal EEGs (IED-), while 39 (22F/17M) had generalized IEDs (IED+). The two groups were compared for age, total brain volume, and sulcal areas (Hotelling's Trace) as well as between-subjects comparison of 11 individual sulcal areas (averaged between left and right hemispheres). There were no differences between IED- and IED+ groups with respect to age or total brain (gray or white matter) volume, and multivariate tests demonstrated a marginally significant decrease of sulcal areas in IED+ baboons (p=0.075). Tests of between-subjects effects showed statistically significant decreases in the intraparietal (p=0.002), central (p=0.03) and cingulate sulci (p=0.02), and marginal decreases involving the lunate (p=0.07) and superior temporal sulci (p=0.08). Differences in sulcal areas in IED+ baboons may reflect global developmental abnormalities, while decreases of areas of specific sulci reflect anatomical markers for potential generators or cortical nodes of the networks underlying spontaneous seizures and photosensitivity in the baboon.
Research on Collaborative Development of Technical Chain and Industrial Chain of Strategic Emerging Industries

Strategic emerging industries are the convergence of emerging technologies and emerging industries and are the important opportunity for developing countries to implement Forging Ahead Strategy. Emerging technologies are the competency or core for the industrial development and emerging industries are the bridge for introducing the emerging technologies to the new market. Collaborative development of technical chain and industrial chain is the key factor for the growth of strategic emerging industries. The theoretical exploration and practices of IoT industry testify that autonomous technical chain should be constructed by the strategy of patent and standard to avoid the technical hollowing-out and should be developed by the innovation of business model to avoid the worthlessness of technical innovations.
Vorrichtung zum Erzeugen eines Unterdruckes

Die Erfindung betrifft eine Vorrichtung zum Erzeugen eines Unterdrucks mit mehreren Ejektoren und einer Aufnahmeeinrichtung für die Ejektoren, wobei die Aufnahmeeinrichtung wenigstens einen Anschluss für eine Druckluftleitung aufweist und dieser Anschluss in ein Druckluftverteilsystem mündet, an das ein Druckluftkanal eines jeden Ejektors anschließbar ist, und für jeden Ejektor ein Unterdruckkanal vorgesehen ist, der mit dem Unterdrucksystem des Ejektors verbindbar ist, wobei die Aufnahmeeinrichtung einen Halterahmen und ein Schnellwechselsystem für die Ejektoren bildet und die Aufnahmeeinrichtung über Steuerleitungen mit den Ejektoren verbunden und mit einer Maschinensteuerung verbindbar ist.
Secure quantum communication and computation

Quantum Theory is one of the greatest scientific revolutions of the twentieth century. During the last decades, it has become apparent that the tools provided by quantum mechanics can be used in many fields, such as cryptography, algorithms, game theory, and even biology. This is because quantum systems exhibit an intrinsic randomness that can be exploited in order to significantly boost computational performance, increase security of communications and in general achieve tasks that are impossible with purely classical means. On the other hand, the use of quantum technologies in future telecommunication networks, raises important questions on the security of the currently deployed protocols since quantum adversaries will be able to use quantum effects to break widely-deployed cryptosystems (e.g. RSA).
The scientific aim of the proposed research project is to build the essential components for secure quantum communication and computing in realistic environments. It stands at the interface between quantum theory and experiments, focusing on the effect of the experimental environment on the implementation and security of different quantum computational models and protocols.  It is expected to pave the way for large-scale quantum cloud computing, so that users can store and process their data on a network using powerful quantum servers, therefore providing a more effective way for computing and communication. The proposed project is highly innovative and interdisciplinary, and it will play an essential role in my career development, since it will allow me to work closely with researchers from different fields and acquire both key scientific and complementary skills.
Surface Modification of Microelectrode for Deep Brain Stimulation

To improve the biocompatibility of micro-electrode for deep brain stimulation(DBS), and to reduce the immune response of brain tissue and thick encapsulation layer surround the electrode, a surface modification was executed on the polyurethane of DBS electrode head.The electrode surface firstly was modified by N_2/H_2 plasma treatments to achieve the active amino group, and then the polypeptide molecule YIGSR was endowed by a polymerization with the amino group on the electrode surface,consequently,the electrode surface had a layer of polypeptide molecule promoting nerve cell growth.The experiment results of modified electrode implant in rat brain confirm that to a certain degree,the modified electrode can reduce the thick encapsulation layer surround the electrode,it is beneficial for contact between electrode and never cells,and the electrode can make a bigger volume of tissue activated.The grafting large-molecule polymer on the polyurethane surface is feasible,and the conclusion gets referable for the further research on bioelectrode surface modification.
La crítica esencialista en los estudios interdisciplinares en EUA. Sobre el proceso de integración de un terreno común en la investigación interdisciplinar.

Una revisión de la literatura actual sobre estudios interdisciplinarios en Estados Unidos de América (EUA), indica que las nociones de terreno común e integración, en tanto claves ontológicas de la esencia interdisciplinar, están generando una larga y densa disputa epistemológica entre dos frentes acádémicos: por un lado, los partidarios del enfoque “integracionista”, y, por otro, los defensores del proceso de “aplicación generalista” de estudios interdisciplinares. Considerando ambas posiciones, este artículo analiza algunas de las formulaciones críticas más desarrolladas respecto al papel que juega tanto el terreno común como la integración en el proceso de implementación de la perspectiva de investigación interdisciplinar. Primeramente, el texto analiza las claves narrativas que han sustentado históricamente a la “tradición integracionista” estadounidense; seguidamente, discute las posiciones críticas antagónicas, basadas en el “enfoque generalista”. Finalmente, cierra valorando cuáles son, y en qué consisten, los supuestos metateóricos centrales que sostienen a ambos frentes.
Implementação de tecnologia inovadora de segurança microbiológica em produtos à base de carne orgânicos, convencionais e livres melhorados JK sp z o.o. — Plant Meat Jasiołka em Dukla

O resultado do projeto através da aquisição de ativos fixos e obras de construção será a criação e implementação de uma nova tecnologia de produção de produtos à base de carne com a adição de soro de leite sem adição de nitritos e nitratos. A nova tecnologia será inovadora e será a primeira a ser aplicada à escala industrial na Polónia.«Tecnologia de soro de leite» tem por objetivo eliminar, até à data, a utilização corrente na indústria de conservantes, como os nitratos e os nitritos, que têm um efeito negativo na saúde humana devido a efeitos mutagénicos e patogénicos. Os nitratos e os nitritos serão substituídos pelo soro de leite ácido obtido a partir do leite de vaca. Os produtos à base de carne criados pela nova tecnologia do soro de leite serão seguros para a saúde e podem ser considerados alimentos saudáveis, e a tecnologia do soro de leite será inovadora e inovadora. A patente tem um efeito sobre: — coloração do produto final — o que dá a possibilidade de eliminar os nitratos (conservantes) da produção — reduzindo significativamente o teor de microrganismos patogénicos naturais na carne — o que se reveste de grande importância, nomeadamente na produção de produtos de cura crus — reduzindo o tempo necessário para preparar a carne para a produção, — melhorando os valores gustativos do produto final através de uma trituração mais eficaz da carne -, prolongando o prazo de conservação do produto final, afetando a transformação das proteínas e dos ingredientes gordos contidos na carne. A tecnologia protegida por patentes permitirá a produção de 3 grupos de produtos: produtos à base de carne certificados por bioalimentos, convencionais e de maturação livre, incluindo a produção de alimentos dietéticos, tais como: •alimentos para crianças, dieta recomendada para uso no tratamento de doenças, com baixo teor de sódio, com teor reduzido de nitratos, contendo sais minerais, para diabéticos e desportos O custo total do projeto é de... mil PLN, incluindo financiamento — «prêmio tecnológico» é... mil PLN. O projeto será executado de... a um ano.
New transversality techniques in holomorphic curve theories

In the study of symplectic and contact manifolds, a decisive role has been played by the theory of pseudoholomorphic curves, introduced by Gromov in 1985.  One major drawback of this theory is the fundamental conflict between ""genericity"" and ""symmetry"", which for instance causes moduli spaces of holomorphic curves to be singular or have the wrong dimension whenever multiply covered curves are present.  Most traditional solutions to this problem involve abstract perturbations of the Cauchy-Riemann equation, but recently there has been progress in tackling the transversality problem more directly, leading in particular to a proof of the ""super-rigidity"" conjecture on symplectic Calabi-Yau 6-manifolds.  The overriding goal of the proposed project is to unravel the full implications of these new transversality techniques for problems in symplectic topology and neighboring fields. Examples of applications to be explored include: (1) Understanding the symplectic field theory of unit cotangent bundles for manifolds with negative or nonpositive curvature, with applications to the nearby Lagrangian conjecture and dynamical questions in Riemannian geometry; (2) Developing a comprehensive bifurcation theory for Reeb orbits and holomorphic curves in symplectic cobordisms, leading e.g. to a proof that planar contact structures are ""quasiflexible""; (3) Completing the analytical foundations of Hutchings's embedded contact homology (ECH), a 3-dimensional holomorphic curve theory with important applications to dynamics and symplectic embedding problems; (4) Developing new refinements of the Gromov-Witten invariants based on super-rigidity and bifurcation theory; (5) Defining higher-dimensional analogues of ECH; (6) Proving integrality relations in the setting of 6-dimensional symplectic cobordisms, analogous to the Gopakumar-Vafa formula for Calabi-Yau 3-folds.