SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Successful Eradication of Multidrug Resistant Acinetobacter in the Helsinki Burn Centre

Multidrug-resistant (MDR) Acinetobacter is an important pathogen implicated in nosocomial infections in healthcare environments. Virulence factors, resistance mechanisms, and limited therapeutic options make this pathogen a major problem currently facing burn intensive care units (ICUs) worldwide. The purpose of this study was to assess the effect of infection control measures taken in Helsinki Burn Centre in 2001 on MDR Acinetobacter prevalence in ICU burn patients. Data were retrospectively collected from patient files from 1998 to 2012. ICU burn patients were defined as those with either over 30% of total body surface area burnt or requiring mechanical ventilation. Inclusion criteria consisted of patients who tested positive for Acinetobacter sp. in routine bacterial cultures or cultures taken because of a clinically suspected infection. Infection control interventions performed in 2001 consisted of various shower room renovations and changes in hospital hygiene and burn treatment regimes. Between 1998 and 2012, 75 patients were diagnosed with Acinetobacter sp. colonization. Following the infection control interventions the incidence of Acinetobacter sp. radically declined. Between 1998 and 2001, there were 31 cases of MDR Acinetobacter colonizations diagnosed, but from 2002 to 2012 no MDR strains were found. Changes to hospital hygiene and wound treatment protocols as well as structural changes to the hospital environment can have a major impact on preventing and treating Acinetobacter outbreaks in burn centers.
The Unique Distribution of Zeros in Compressing Sequences Derived from Primitive Sequences over Z/(p(e))

Let Z/(p(e)) be the integer residue ring with odd prime p and integer e >= 3. Any sequence (a) under bar over Z/(p(e)) has a unique p-adic expansion (a) under bar = (a) under bar (0) + (a) under bar (1) . p+ ... +(a) under bar (e-1) . p(e-1), where (a) under bar (i) can be regarded as a sequence over Z/(p) for 0 <= i <= e - 1. Let f (w) be a strongly primitive polynomial over Z/(p(e)) and let (a) under bar, (b) under bar be two primitive sequences generated by f (x) over Z/(p(e)). Assume phi(x(0), ... , x(e-1)) = x(e-1) + eta(x(0), ... , x(e-2)), where the degree of x(e-2) in eta(x(0), ... , x(e-2)) is less than p-1. It is shown that if phi(a(0)(t), ... ,a(e-1) (t)) = 0 if and only if phi(b(0)(t), ... , b(e-1)(t)) = 0 for all nonnegative integer t with alpha(t) not equal 0, where (alpha) under bar, is an m-sequence determined by f (x) and (a) under bar (0), then (a) under bar = (b) under bar. In particular, when eta(x(0), ... , x(e-2)) = 0, it is just the former result on the unique distribution of zeros in the highest level sequences.
Analysis of The GEO multipath impact on Ionosphere-Free Combination Positioning in BDS system

the satellites constellation of BeiDou regional navigation satellite system (BDS) is different from GPS, which consists of Geostationary Orbit (GEO), Inclined Geosynchronous Orbit (IGSO) and Medium Earth Orbit (MEO). Due to the different constellation of navigation system, there should be some special characteristics of BDS to be analyzed thoroughly. For example, when used Ionosphere-Free Combination Positioning algorithm (IF) in BDS, the positioning accuracy performs worse than Single frequency positioning. This paper studies the genuine causes of this phenomenon initially. From the analysis, GEO multipath error should be the main reason which caused this phenomenon. GEO multipath error changes slowly, even calls “standing multipath error”. This paper analyzes this phenomenon and characteristics of GEO multipath error, then proposes an amended algorithm to estimate GEO multipath error. Finally used computed multipath error to correct Ionosphere-Free Combination Positioning. The simulation results show a significant promotion in positioning accuracy.
‘When I Can Come on Time I'll be Ready to Finish’: Meanings of Lateness in Psychoanalytic Psychotherapy

This paper considers some aspects of the meaning of chronic lateness in psychoanalytic psychotherapy. The central role of time in psychoanalytic work and the significance of enactments around the analytic frame are considered. Using clinical material the writer explores how lateness can be understood as an expression of global difficulties in accepting and adapting to the demands of reality as well as a wide range of complex object-relationship difficulties. Some of the technical and countertransference complexities of dealing with lateness are discussed. Lateness is seen to project intolerable experiences into the therapist, to demonstrate the patient's intense difficulties in imagining and tolerating a productive couple, to re-enact a sadomasochistic dynamic from the patient's past and to re-encounter/re-address the patient's early experiences of rejection and oedipal rivalries. The eventual synchronization of therapist and patient's times is explored as a major achievement in the patient's increasing capacity for relating.
Shearer Shaft Roundness Error of Signal Processing

For the measurement of shearer shaft geometry signal contain the axis of rotation error and the measurement error, made of two separate programs from shearer shaft the geometric method of measuring signal acquisition and signal processing error. The program is based on the analysis of the shearer shaft Two-point method of roundness measurement method and error separation technique. Using two displacement sensors and a combination of programs to measure the angle sensor, and an equation using the Fourier transform of elimination and separated from the measurement signal roundness. Then, 53H, and wavelet signal Noise algorithm such as the error of roundness error signal separation. Simulation results show that the method has a higher real value and better convergence for coal mining shaft roundness error in the separation of signal processing.
Process for inserting connecting elements in the front and/or lateral sides of technical timber products

The method involves transferring a connecting element (4) into a core warehouse (6). The connecting element is supplied over a conveyor device e.g. belt conveyor, in a transfer arrangement with a separating station for separating individual connecting elements. The individual connecting element is raised or lowered to a height of a groove in a technical wood product (3). The connecting element is impressed for continuously transporting the technical wood product from a pressing assembly (8) into the groove in the wood product in a program controlled manner. An independent claim is also included for a device for inserting a connecting element in front and/or lateral sides of a technical wood product i.e. floor panel.
22 ADHERENCE TO AND PERSISTENCE WITH AN ORAL METRONOMIC CHEMOTHERAPY WITH CAPECITABINE IN HEAVILY PRETREATED METASTATIC BREAST CANCER (MBC) PATIENTS

s / Cancer Treatment Reviews 36S3 (2010) S95–S119 S101 histochemical expression of HER-2 growth factor. With a median follow-up of 18 months (range 11–35) there were 16 pts (70%) with no evidence of disease; 4 patients (17%) were alive with disease; and 3 patients (13%) died of the disease. Relapse was detected in 7 women (30%), lung, brain, and chest wall recurrence being the most common sites of metastasis. Among those 7 cases, 5 are triple negative and one patient had obtained a complete pathological response. Conclusions: Our data suggest an improvement in locoregional control in patients treated by surgery, in conjunction with chemotherapy based on antracycline and radiotherapy, for LABD. Moreover, patients with triple-negative disease are a poor prognosis and at high incidence of early metastatic recurrence. 21 DUCTAL CARCINOMA IN SITU OF BREAST: ANALYSIS OF 232 CASES T.P. Latiano, C. D’Addetta, L. Lombardi, M. Morritti, A. Piano, R. Murgo, M. El Jaouni, M. Copetti, E. Maiello. Oncology Unit, Surgery Unit, Unit of Radiotherapy, Unit of Biostatistics, IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy Background: Ductal carcinoma in situ (DCIS) is a heterogeneous, unicentric precursor of invasive breast cancer, which is frequently identified through mammographic breast screening programs. The prognostic factors of DCIS include anatomo-pathologic factors, age and molecular factors. Methods: Two-hundred-thirty-two woman with DCIS were retrospectively reviewed between 1996 and 2009 in our Institution. The main characteristics of these pts were: median age 53 years (range 23–78), menopause 154 pts (66.3%), fertility 192 pts (82.7%); 50 pts (21.5%) were treated with mastectomy, 182 (78.4%) with breast conservation, and 171 (93.3%) received radiotherapy. Moreover, 106 pts (45.6%) received tamoxifen. Results: With median follow-up of 55 months (range 4–170), recurrence rate was 4.7% (11 pts: 8 ipsilateral, 2 controlateral and 1 ipsilateral + controlateral synchronous). Median relapse free survival was 44.5 months (range 23–68). Approximately 90% of these recurrence have received a breast conservation developing invasive cancer. All these pts had more than 40 years (range 40–66; median 49) and 6/11 were between 40 and 50 yrs. Histologically, 10/11 pts presented comedocarcinoma and 8/11 positive surgical margins. Nine of these woman underwent breast irradiation (90%) and only four pts (36%) ormonal therapy with tamoxifen. The overall survival of all group was 98.2%. Conclusions: Our retrospective analysis confirm the usefulness of mastectomy for patients with DCIS: in fact, breast radical surgery was associated with optimal local control. Furthermore, we observed that pts with 40–50 yrs and comedocarcinoma histology might be considered at high risk of local recurrence and therefore the age and the histology might be considerate as predictors of
Novel quantum phase transition from bounded to extensive entanglement

Significance One of the main quests of many-body physics and quantum information is to understand various quantum phases and in particular the entanglement present in them. In this work we have uncovered a unique, physically transparent quantum phase transition in a spin chain where entanglement entropy itself jumps from low scaling, most typical for gapped models and short-range correlations, to a critical phase where the scaling exhibits an extraordinary amount of entanglement. This discovery pushes the boundaries of a possible range of nonlocal quantum correlations displayed by local Hamiltonians and opens a door to fundamental and practical questions about the interplay of entanglement and locality in many-body systems.
Micro-scale nuclear magnetic resonance on III-V semiconductors and the advance of mechanically detected NMR

To understand the properties of III/V semiconductors, knowledge about the ordering and the atom structure are of crucial importance. Nuclear magnetic resonance (NMR) is a versatile tool that can be used to perform such an investigation. In the research of this doctoral thesis two thin film III/V semiconductors AlGaAs en InGaP are investigated with NMR. In both samples the obtained spectra did not indicate long range cation ordering. A big difference between the two semiconductors is the high stress in the InGaP lattice relative to the AlGaAs lattice because of the difference in lattice constants.In both semiconductors the quadrupolar (spin>½) distributions are measured and modelled.. The second part entails magnetic resonance force microscopy (MRFM). The MRFM design choices of a new probe and the results are presented. MRFM allows the measurement of all spin nuclei of the thin film AlGaAs with an extremely small volume. Furthermore, the polarization transfer of Phosphor to Fluor in KPF6 was studied and the influence of nuclear spin diffusion on the magnetization of Fluor in KPF6
Equilibrium-Phase High Spatial Resolution Contrast-Enhanced MR Angiography at 1.5T in Preoperative Imaging for Perforator Flap Breast Reconstruction

The aim was (i) to evaluate the accuracy of equilibrium-phase high spatial resolution (EP) contrast-enhanced magnetic resonance angiography (CE-MRA) at 1.5T using a blood pool contrast agent for the preoperative evaluation of deep inferior epigastric artery perforator branches (DIEP), and (ii) to compare image quality with conventional first-pass CE-MRA.Twenty-three consecutive patients were included. All patients underwent preoperative CE-MRA to determine quality and location of DIEP. First-pass imaging after a single bolus injection of 10 mL gadofosveset trisodium was followed by EP imaging. MRA data were compared to intra-operative findings, which served as the reference standard.There was 100% agreement between EP CE-MRA and surgical findings in identifying the single best perforator branch. All EP acquisitions were of diagnostic quality, whereas in 10 patients the quality of the first-pass acquisition was qualified as non-diagnostic. Both signal- and contrast-to-noise ratios were significantly higher for EP imaging in comparison with first-pass acquisitions (p<0.01).EP CE-MRA of DIEP in the preoperative evaluation of patients undergoing a breast reconstruction procedure is highly accurate in identifying the single best perforator branch at 1.5Tesla (T). Besides accuracy, image quality of EP imaging proved superior to conventional first-pass CE-MRA.
Istplus - postdoctoral fellowships

ISTplus offers two-year fellowships for highly qualified, incoming postdocs fulfilling the mobility criterion, who will have the chance to join our world-class research teams in the fields of Biology, Neuroscience, Mathematics, Physics, and Computer science at IST Austria. The fellows will be integrated in a truly interdisciplinary research environment, interacting closely with colleagues from different fields (through shared facilities, joint projects, and events). The international dimension will be ensured by the multinational teams (with employees from more than 50 countries) and through international networking. 

An open, bottom-up international recruiting process will ensure scientific quality and potential of the selected ISTplus fellows. Already at the beginning of their stay, fellows together with a Career Counselor will assess their professional profile and skill set, define the direction of their future career path (be it academic or non-academic) and elaborate a development plan, supported by our Targeted Competence Building Program. A co-supervision scheme will support the fellows during their stay, meant to oversee scientific progress, but also to give advice regards individual career planning.

A secondment scheme should kick-start and facilitate cross-boundary networking and translational research with an intersectorial network of excellent partners, incl. SMEs, applied research companies, organizations in the field of tech transfer and science education, and commercial enterprises. Fellows will be supported in the choice of the right partner, in setting up a research plan, and may opt for an extension of the fellowship for up to six months to enable intersectoral mobility. Various events, workshops, trainings, and further activities in the area of tech transfer will cultivate an open-minded entrepreneurial spirit among program participants.
ALSAMA

THE INTERVENTOCONSISTE IN THE RENOVATION OF A PROPERTY LOCATED IN THE MUNICIPALITY OF CANICATTÃ¬ TO BE USED FOR ACCOMMODATION/TURISTICACON TYPE OF GUEST HOUSE.
An Early Detection Method of Type-2 Diabetes Mellitus in Public Hospital

Diabetes is a chronic disease and major problem of morbidity and mortality in developing countries. The International Diabetes Federation estimates that 285 million people around the world have diabetes. This total is expected to rise to 438 million within 20 years. Type-2 diabetes mellitus (T2DM) is the most common type of diabetes and accounts for 90-95% of all diabetes. Detection of T2DM from various factors or symptoms became an issue which was not free from false presumptions accompanied by unpredictable effects. According to this context, data mining and machine learning could be used as an alternative way help us in knowledge discovery from data. We applied several learning methods, such as instance based learners, naive bayes , decision tree, support vector machines, and boosted algorithm acquire information from historical data of patient’s medical records of Mohammad Hoesin public hospital in Southern Sumatera. Rules are extracted from Decision tree to offer decision-making support through early detection of T2DM for clinicians.
Assembly of Fe/S proteins in bacterial systems

Iron/sulfur clusters are key cofactors in proteins involved in a large number of conserved cellular processes, including gene expression, DNA replication and repair, ribosome biogenesis, tRNA modification, central metabolism and respiration. Fe/S proteins can perform a wide range of functions, from electron transfer to redox and non-redox catalysis. In all living organisms, Fe/S proteins are first synthesized in an apo-form. However, as the Fe/S prosthetic group is required for correct folding and/or protein stability, Fe/S clusters are inserted co-translationally or immediately after translation by specific assembly machineries. These systems have been extensively studied over the last decade, both in prokaryotes and eukaryotes. The present review covers the basic principles of the bacterial housekeeping Fe/S biogenesis ISC system, and related recent molecular advances. Some of the most exciting recent highlights relating to this system include structural and functional characterization of binary and ternary complexes involved in Fe/S cluster formation on the scaffold protein IscU. These advances enhance our understanding of the Fe/S cluster assembly mechanism by revealing essential interactions that could never be determined with isolated proteins and likely are closer to an in vivo situation. Much less is currently known about the molecular mechanism of the Fe/S transfer step, but a brief account of the protein–protein interactions involved is given. This article is part of a Special Issue entitled: Fe/S proteins: Analysis, structure, function, biogenesis and diseases. • Basic principles of the bacterial housekeeping Fe/S biogenesis ISC system • Structural and functional characterization of binary and ternary complexes involved in Fe/S formation on IscU • The importance to work with protein complexes versus isolated proteins • Proposed mechanisms for Fe/S clusters assembly on IscU: roles of frataxin
The extensive and ubiquitous role of polycyclic aromatic hydrocarbons (pahs) in space

Large Polycyclic Aromatic Hydrocarbon (PAH) molecules are deeply interwoven in the fabric of the Universe and lock up ~15% of the elemental carbon in the interstellar medium (ISM) of galaxies. They dominate the mid-infrared emission characteristics of galaxies that can be used to trace star formation locally as well as in the early universe, they influence the phase structure of the ISM and the star formation rate of galaxies, and they are the epitome of molecular complexity in space, heralding the importance of top-down chemistry. In spite of the influential role of PAHs in the ISM, their lifecycle, catalytic activity, interaction with interstellar radiation, gas and grains and their role in the organic inventory of solar system bodies is still poorly understood. The EUROPAH ETN aims to change this by creating a highly multidisciplinary network that combines astronomy, molecular physics, molecular spectroscopy, environmental science, quantum chemistry, surface sciences, and plasma physics in a comprehensive research and training program. EUROPAH will train 16 ESRs through cutting edge individual research and innovation projects investigating key physical and chemical processes of PAHs in space and related terrestrial settings and linking directly to R&D needs of our industrial beneficiaries. EUROPAH will engage all ESRs in industry driven innovation activities aimed at R&D of the industrial participants products and services, including outreach activities led by our industrial science communication beneficiary. Research and innovation training is complemented by an extensive program of network-wide training events to expose ESRs to all disciplines in the network and to instill in them a comprehensive set of transferable skills. This will provide the ESRs with a unique learning environment in a multidisciplinary setting aimed at developing a research oriented creative and innovative mind set and will place them well for a future career in academia or in industry.
Optimizing the impact of public policies in favour of research and innovation facilities in the field of medical technologies

CONTEXT:
Medical technologies are a key sector for the future in Europe by bringing solutions to reduce healthcare costs in a context of ageing population. With emergence of new and cross-sectorial technologies, it is one of the most innovative high-tech sector which faces a strong world competition requiring each time more innovation. But the sector is fragmented with a high number of products and SMEs; RDI infrastructures offers do not always meet effectively companies demands.

PARTNERSHIP:
The project brings together 9 partners from 8 EU countries (FR, IT, NL, D, FI, DK, HU, PL) with a mix of regional public authorities, innovation agencies and a cluster (all having delegation of competencies from their public authority) and an advisory partner. They are supported by strongly involved skilful stakeholders: managing authorities, centres of research, clusters, hospitals.

OBJECTIVE:
Improving public policies (structural funds and regional policies) in favour of RDI facilities to be more adapted to the specificities of the medtech domain.

APPROACH:
In phase 1, the project follows a progressive 3-steps approach starting from a state of the play in each partner’s region from which best practices will be cross-analysed to deliver recommendations in order to improve the policies addressed in partners’ regions.

MAIN ACTIVITIES/ OUTPUTS:
The project will lead to the implementation of 8 local action plans thanks various activities of exchange of experiences, among which self-assessment, benchmarking, interregional mapping and joint analysis, 1 interregional seminar, 3 study visits, 4 workshops, 4 dissemination events (2 at European level to fuel the EU reflection).

MAIN EXPECTED RESULTS:
Increase knowledge and skills among stakeholders and staff members (50). 20 best practices and 8 improved policies instruments (5 related to structural funds) to strengthen RDI ecosystems, develop new RDI business models and new RDI interregional projects at EU level in the medtech sector.