SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Application of different nanocarriers for encapsulation of curcumin

Curcumin is the main polyphenol of the curcuminoid class of turmeric, a well-known spice belonging to the ginger family. In addition to its common applications like coloring and antioxidant agent as food additives, it has a broad range of favorable biological functions, such as anti-inflammatory, anti-microbial, anti-diabetic activities, and anti-cancer potentials against various cancers. However, curcumin suffers from some limitations including short shelf life due to its poor chemical stability, low bioavailability due to its poor absorption, low water solubility, rapid metabolism and rapid systemic elimination. Nanoencapsulaion has been addressed as an innovative and emerging technology for resolving these shortcomings. In this review, the different delivery systems used for loading of curcumin have been considered and explained including lipid-based, chemical polymer and biopolymer-based, nature-inspired, special equipment-based and surfactant-based techniques. Also, implications of nanoencapsulated curcumin in food, pharmaceutical and cosmetic uses are discussed. In this sense, the relevant recent studies in the past few years along with upcoming challenges have been covered. Although incorporation of curcumin into nanocarriers can be a possible solution to overcome its inherent constraints, there are some rational concerns about their toxicological safety once they enter into the biological paths. Therefore, future investigations could focus on assessment of their biological fate during digestion and absorption within human body.
Semiconductor Laser Multi-Spectral Sensing and Imaging

Multi-spectral laser imaging is a technique that can offer a combination of the laser capability of accurate spectral sensing with the desirable features of passive multispectral imaging. The technique can be used for detection, discrimination, and identification of objects by their spectral signature. This article describes and reviews the development and evaluation of semiconductor multi-spectral laser imaging systems. Although the method is certainly not specific to any laser technology, the use of semiconductor lasers is significant with respect to practicality and affordability. More relevantly, semiconductor lasers have their own characteristics; they offer excellent wavelength diversity but usually with modest power. Thus, system design and engineering issues are analyzed for approaches and trade-offs that can make the best use of semiconductor laser capabilities in multispectral imaging. A few systems were developed and the technique was tested and evaluated on a variety of natural and man-made objects. It was shown capable of high spectral resolution imaging which, unlike non-imaging point sensing, allows detecting and discriminating objects of interest even without a priori spectroscopic knowledge of the targets. Examples include material and chemical discrimination. It was also shown capable of dealing with the complexity of interpreting diffuse scattered spectral images and produced results that could otherwise be ambiguous with conventional imaging. Examples with glucose and spectral imaging of drug pills were discussed. Lastly, the technique was shown with conventional laser spectroscopy such as wavelength modulation spectroscopy to image a gas (CO). These results suggest the versatility and power of multi-spectral laser imaging, which can be practical with the use of semiconductor lasers.
LABKIT: Labeling and Segmentation Toolkit for Big Image Data

We present LABKIT, a user-friendly Fiji plugin for the segmentation of microscopy image data. It offers easy to use manual and automated image segmentation routines that can be rapidly applied to single- and multi-channel images as well as to timelapse movies in 2D or 3D. LABKIT is specifically designed to work efficiently on big image data and enables users of consumer laptops to conveniently work with multiple-terabyte images. This efficiency is achieved by using ImgLib2 and BigDataViewer as well as a memory efficient and fast implementation of the random forest based pixel classification algorithm as the foundation of our software. Optionally we harness the power of graphics processing units (GPU) to gain additional runtime performance. LABKIT is easy to install on virtually all laptops and workstations. Additionally, LABKIT is compatible with high performance computing (HPC) clusters for distributed processing of big image data. The ability to use pixel classifiers trained in LABKIT via the ImageJ macro language enables our users to integrate this functionality as a processing step in automated image processing workflows. Finally, LABKIT comes with rich online resources such as tutorials and examples that will help users to familiarize themselves with available features and how to best use LABKIT in a number of practical real-world use-cases.
Automatic size and variance determination for better surface splatting quality on close-up view

Surface splatting has been proven to be a viable alternative to traditional polygon rendering for highly detailed models. In terms of rendering performance, surface splatting has surpassed polygon rendering when it fully exploits today's graphics processing units (GPU). However, in terms of rendering quality, surface splatting could still be inferior to polygon rendering when the model is viewed close-up and when the size and variance of each splat is not computed properly. In this paper, we present a method that improves the image quality of surface splatting to the level comparable to polygonal rendering by automatically finding a suitable size and variance for each splat.
Face cradles, or head cradles

Improved face cradles, more properly called head cradles, provide increased comfort for clients. Various embodiments of novel frontal and temporal skull support pads eliminate the discomforts of existing face cradles. The head cradle embodiments remove the pressure caused by conventional horseshoe face cradles. These pressures can cause facial discomfort, congestion, and restricted breathing, all of which can adversely affect the ability of the user to maximize relaxation. In addition to novel pad embodiments, the head cradles features embodiments whereby the support bars that attach to the support pads, as well as the support pads, can provide a variety of possible adjustments (e.g. lowered, raised, widened, narrowed, lengthened, and angled) to accommodate individual users. Some embodiments mimic fingers of human hands.
Mapping bacterial division in bacillus subtilis

The bacterial cell cycle is of fundamental importance and an important potential antibiotic target; however, many details of
the molecular mechanisms involved remain elusive. Sporulation in Bacillus subtilis is an important model system for cell
cycle studies. Here, I propose applying the ribosome profiling method, not only to identify novel factors involved in the of B.
subtilis cell cycle, but also to create a map of factors regulating this process. I will use advanced genetic methods and
microscopic techniques to characterize the functions of the novel factors, gaining insights into their role in the cell cycle. My
extensive experience in prokaryotic translation gained in the laboratory of Dr. Daniel Wilson in Munich, Germany, combined
with the exceptional genetics and cell biology expertise of the laboratory of Prof. Jeff Errington in Newcastle, England,
creates a great opportunity to study important fundamental aspects of bacteria, with potential implications for healthcare,
drug discovery and industrial biotechnology, as well as providing the foundation for a successful independent career in
science.
Mining geohazards susceptibility and risk mapping: The case of the Amyntaio open-pit coal mine, West Macedonia, Greece

During the last decades, numerous methodologies for the construction of both susceptibility and risk maps have been developed in order to identify and mitigate geohazards such as landslides and secondarily land subsidence phenomena caused by the collapse of natural or man-made underground cavities. According to literature review, the conducted research concerning the assessment of land subsidence risk due to the overexploitation of the aquifer is still at an early stage. This study focuses οn the land subsidence phenomenon due to the overexploitation of the aquifer occurring in the Amyntaio basin in West Macedonia, hosting the active Amyntaio open-pit coal mine. This phenomenon has caused significant damage to settlements, farmlands and infrastructure. In order to construct susceptibility and risk maps knowledge of the geological, geotechnical, hydrogeological and tectonic settings of the study area is required. The proposed methodology for the production of a susceptibility and a risk map of land subsidence was based on the semi-quantitative method Weighted Linear Combination (WLC). The results were evaluated with an extensive field survey action recording, besides the above-mentioned settings, the spatial distribution of surface ruptures. The excellent agreement between the produced maps and the findings of the field survey, proved the added value of the maps, assigning them as crucial tools for the management of land subsidence phenomena.
The role of dopamine in the regulation of sleep and circadian rhythms

Alterations in sleep/wakefulness behavior are among the most debilitating and highly prevalent non-motor symptoms of many neurological and psychiatric disorders that originate from perturbations of the Dopamine (DA) system. Currently, no effective therapeutic strategies are available to alleviate these symptoms. Inspired by my Ph.D results, the current proposal aims to investigate in detail the role of dopamine in the regulation of sleep and circadian rhythms. The main question under investigation is; By what mechanisms DA regulates sleep and circadian rhythms and how are these affected in diseases (such as Parkinson)? Two transgenic mouse models will be used; the first model (MitoPark) shows, like in Parkinson’s disease (PD) patients, a progressive age-dependent neurodegeneration of DA neurons. The second model (CircaDA) lacks functional clock gene oscillations selectively in DA neurons. Using polysomnography in MitoPark mice, a detailed investigation of the consequences of DA loss on sleep regulation will be performed. In-vivo multiunit electrophysiology will be used in both mouse models to study the role of the circadian changes in DA neurotransmission in driving and/or synchronizing the electrophysiological properties of striatal and cortical neurons. Finally, selective DA receptor drugs will be combined with in-vitro patch clamp electrophysiology and in-vitro Per2-bioluminescence to investigate the molecular pathways used by DA to modulate multiple electrophysiological correlates of clock gene oscillations. Collectively, this proposal holds promising fundamental and translational insights for sleep problems experienced by patients suffering from DA-related disorders and is expected to significantly contribute in fostering the academic career of the researcher and the competences of the hosting laboratory in Neurodegenerative diseases.
NOVO APRIMORAMENTO TURÍSTICO DA ALDEIA DE COSTOZZA

PARNASO SRL É UMA NOVA INICIATIVA EMPREENDEDORA ATIVADA NO CONCELHO DE LONGARE (VI) ALDEIA «COSTOZZA», DESTINADA A OFERECER ALOJAMENTO E SERVIÇOS AOS TURISTAS. ESPAÇOS DESUTILIZADOS SERÃO REFUNCIONADOS E ATUALIZADOS COM EQUIPAMENTOS NECESSÁRIOS PARA A REALIZAÇÃO DE EVENTOS, COMO CURSOS DE COMIDA E VINHO E SEMINÁRIOS DESTINADOS A DESCOBRIR O TERRITÓRIO DO CONCELHO DE LONGARE E SUA EXCELÊNCIA. L — O INVESTIMENTO INCIDIRÁ NA "RENOVAÇÃO E MOBILIÁRIO DOS QUARTOS PARA UTILIZAÇÃO DE ALOJAMENTO TURÍSTICO E DAS SALAS EM QUE TERÃO LUGAR A FORMAÇÃO CULINÁRIA E OS EVENTOS CULTURAIS. A PARTE RESTANTE DAS DESPESAS PREVISTAS INCLUIRÁ A AQUISIÇÃO DE EQUIPAMENTO DESPORTIVO: N.4 TREKKING E-BIKES A SEREM DISPONIBILIZADOS AOS TURISTAS, EQUIPAMENTOS PARA A REALIZAÇÃO DE AULAS DE CULINÁRIA E CONSTRUÇÃO DO SITE DA EMPRESA. O PROJETO OFERECERÁ, POR UM LADO, UMA NOVA OPORTUNIDADE BEM ORGANIZADA DE SERVIÇO DE «ALOJAMENTO TURÍSTICO EXTRA HOTELEIRO» NO TERRITÓRIO DAS COLINAS BERICI E — ALT
A method of target identification with UWB based on genetic algorithm and fuzzy pattern recognition

Ultra wideband (UWB) signal has a broad spectrum and high resolution; therefore it is potential in communication and identification areas. At present, for the communication perspective, UWB wireless sensor network (WSN) plays an important role. And for the identification perspective, UWB radar, radar, passive radar and WSN with special sensors make a great achievement. In the paper, a novel method of target identification with UWB based on genetic algorithm (GA) and fuzzy pattern recognition (FPR) is proposed. This method integrates communication and targets identification. Firstly, extensive UWB measurement data are got from the foliage environment with different kinds of targets. Secondly, character parameters related to targets information are extracted from the received signals and the target prediction function is built based on these parameters. Finally, based on FPR, the maximal membership principle is used to identify the targets and GA is used to get near-optimal solution of the sub-membership functions. The recognition results demonstrate that the method is effective to identify targets.
Ergonomic loading apparatus for electroplating processes

A loading apparatus for use in electroplating processes includes a container designed to sealingly receive a plurality of airfoil blades fitted with gaskets. Each fitted airfoil blade is disposed in contact with a plurality of electrical contact assemblies having a spring-like design which ensures an adequate connection is made and complete plating of the airfoil blades occurs.
ASSESSMENT OF RELATIONSHIP AMONG SLEEPINESS WITH POLYSOMNOGRAPHIC PARAMETERS IN PATIENTS WITH OSA

Background: Sleepiness that occurs at inappropriate or undesirable times or that interferes with daytime activities is generally considered excessive daytime sleepiness. Obstructive Sleep Apnea (OSA) is one of the most common causes of excessive daytime sleepiness. The aim of this study is to finds out the most important nocturnal polysomnographic parameters influencing daytime sleepiness in patients with OSA.
Materials and Methods: Considering the inclusion and exclusion criteria, 112 patients referred to Baqiyatallah subspeciality sleep clinic in Qom city were selected. Patients, demographic and Epworth Sleepiness Scale (ESS) data were gathered and then comparison among ESS with polysomnography and anthropometric parameter was performed. Chi-square was used for analysis of qualitative parameters. Data analysis was done by SPSS v.18. P value was significant (˂0.05).
Results: The mean age of the cases was 55.07 with male frequency 58.9% and female 41.1%. Body mass index was 34.34, apnea hypopnea index 43.62, mean Arousal Index 30.64 and mean ESS was 12.83. There was significant relationship among ESS>10 with arousal index (p=0.009) and mean O2 saturation (p=0.029), But we didn’t detected correlation between ESS>10 with other polysomnographic parameters. 
Conclusion: According to the data, the most important parameters of sleepiness in obstructive sleep apnea patients were sleep fragmentation and mean O2 saturation.
Keyword: Obstructive sleep apnea, Excessive daytime sleepiness, Arousal.
High phytosterol variants towards improved feedstocks and biofortification of crops

Phytosterols (PS) are valuable biomolecules used as nutrients and as feedstock material for the pharmaceutical and cosmetic industries. The challenge biologists and breeders are faced with is to develop bioengineering programs and valuable crops dedicated to the large-scale production of PS, which are currently extracted from agricultural waste materials. The goal of the proposal is to identify master regulators of PS biosynthesis and accumulation in plants. In fact, PS have essential cellular functions in plant growth and development, acting as key membrane components and membrane reinforcers, as signals in development and as precursors of brassinosteroids, a class of growth regulators. As such, the concentration of PS is highly regulated in order to comply with cellular homeostasis. To reach the goal, we will carry out a functional molecular characterization of a tobacco variant carrying a yet unknown semi-dominant mutation responsible for PS overproduction and  Arabidopsis thaliana mutants exhibiting a suppressor phenotype of a defect in the production of precursors of isoprenoid lipids, such as PS. The work plan is to apply advanced genomics for next-generation mapping, leading to the elucidation of mutations in genes of interest (GOI) that regulate PS accumulation. The validation of candidate GOI will be done by genome editing and the role of novel alleles in PS metabolism will be performed by various functional and metabolomic studies. Finally, the combined expression of selected GOI with steroidogenic enzymes will be assessed by implementing in folia expression assays in Nicotiana benthamiana.
A METHOD, A SYSTEM AND AN APPARATUS FOR IN SITU PROCESSING OF AN OIL SHALE FORMATION

A method, system and apparatus using injection (124) and producer (128) wells to create underground fluidised bed retort systems (110). A cavern (118) for the retort system (110) may be created without the use of explosive mining methods, conventional fracking or other fragmentation methods. The cavern (118) and the fluidised bed (120) are created by the use of high pressure injection jets of pure hot hydrogen gas (H2) and steam upon an oil shale rock (112).
Imago Relationship Therapy and Accurate Empathy Development

Fourteen individuals participated in Imago relationship therapy (IRT) group training and intervention. The sessions were carried out at a public institution of higher education in the southwest and facilitated by a certified Imago therapist. The study followed an experimental–control group design. Findings indicate that while accurate empathy responding remained low, as well as constant, across time in the control group, participation in the IRT sessions strongly increased one's ability to accurately empathize with their partner/spouse. This study provides strong evidence for a theoretical goal of IRT, namely that it improves accurate empathic responding for individuals who have received the intervention.
Digitalização para aumentar a competitividade do monnument d.o.o.

O projeto «Digitalização para melhorar a competitividade do monnument d.o.o.» visa fortalecer a competitividade da empresa através do investimento em novos equipamentos, capazes de fornecer a digitalização da documentação aos seus clientes, o que ajudará a reduzir o consumo de papel, ter um impacto positivo no meio ambiente, aumentar a receita da empresa em 50 %, preservar o emprego existente e criar três postos de trabalho. A duração prevista do projeto é de 6 meses. O total dos custos elegíveis é de 252.030,81 HRK.
DREADFUL NEWS FROM WAPPING (AND ELSEWHERE): GENDER, READING AND THE SUPERNATURAL IN EARLY MODERN ENGLAND

Scenes of books and reading are often prominent in accounts of early modern women's encounters with the supernatural. This reveals a number of significant things about the way reading was conceptualized in the period, especially about the anxieties on the part of (largely educated male) authors about the extension of reading to the young, the female, and the lower class, and the fantasies of these subjects to transgress a demandingly bibliocentric Protestant culture. In these narratives, three elements converge—the supernatural, the uncontrollable act of reading and the leaky female body—all of which raised anxieties about proper boundaries, rational subjectivity, and the power of the state and church to authorize meanings and control behaviour, leading to the representation of reading as essentially uncanny.
Grideye state estimation of medium voltage distribution systems

GEiMS will be the first ever project to enable the realistic and prompt application of decentralized State Estimation (SE) at Medium Voltage (MV) Distribution Systems (DS) of electricity. A wide, concise, adaptive and straight-forward SE framework for MV DS will be delivered, based on the novel, but readily available features of the GridEye Base Module (GBM) equipment, which is integrated over GridEye Network Supervision, a fully operational monitoring and control ICT platform, both developed by DEPsys (host institution of GEiMS). The Experienced Researcher (ER) will contribute greatly to GEiMS thanks to his vast experience in the recent years of his studies and work on the field of MV DS. To achieve the goals of GEiMS, first, the calculation of the phasors performed by the GBM equipment will be improved, based on proper time domain models of the DS infrastructure. Following, and since SE may be viewed as an optimization problem, the GEiMS platform will include distributed optimization techniques to realize SE for MV DS. However, due to the limited availability of metering (and, thus, processing) infrastructure at DS, a complementary decentralized SE method will also be added to the GEiMS platform. Given the special characteristics of DS, the correlation of errors across types of the measurements and pseudomeasurements required in SE methods will be explored extensively. The GEiMS framework will also account for practical critical issues that may threaten the integrity of SE and devise plans to ensure improved efficiency of the tool under all circumstances. The framework will be assessed on an actual test-bed distribution feeder. The whole GEiMS project will be developed in close collaboration with Swiss and European DSOs, thus ensuring its practical value for the R&D panel at hand, as also offer ample potential and opportunities to the ER leading this work.
AXIAL DISC BRAKE AND THREAD FEED FITTED THEREWITH

In an axial disc brake (B), especially for a thread feed, having dynamically balanced and dimensionally stable braking surfaces (1, 2) pressed against each other yieldingly by under a predetermined pressure, one of which has a central withdrawal aperture and is arranged on a brake component which is supported to move at least axially, one braking surface (1) is spherically convex and the other (2) is tapered with a taper axis fitting at least approximately in the axis (3) of the disc brake (B) and the taper generator in the contact region (C) of the braking surfaces (1, 2) is a tangent (T) of the generating circle of the spherically convex braking surface (1). The axial disc brake (B) is preferably fitted on the front of a storage drum (D) of a thread feed (F) for a gripper or shuttle loom in such a way that the thread unwinding over head clockwise from the storage drum (D) and rotating along a thread guide (6) is taken directly without deflection into the contact region of the braking surface and is only gently deflected axially again after passing the contact region.