SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Boosting European Games Industry

Once the economic force of Creative Industries (CI) was showcased by several studies,the development of strong digital+interactive media strategies is still high on the agenda throughout Europe. 
Especially the digital games market is a fast growing market within CI:The global demand for digital games is expected to grow 10% annually in the next years.Today the production of dig.games is an internat.industry.By now,the European games industry contributes more than 3,5bn Euro p.a.to the economy and employs more than 100.000 people,including 60.000 skilled jobs. 
Games could represent a new source of growth for Europ.economy but many regions are still missing adequate policies+funding schemes which could sustain this market.Further,funding+support mechanisms often do not meet the special needs of the small+innovative game developers. 
Aim of the BOO-Games project is to support the pub.reg.development authorities in understanding the importance of the games industry for the Europ.economy.
Particularly, it will focus on the challenges policy makers are either not yet aware of or which they are already facing,as game relevant questions move up on the political agenda due to their economical+societal impact.Thus the project will centre on different elements,among them: Public funding,private investment incentives,talent incubation,cluster development +improvement of public perception of digital games potential as well as risk management for public authorities in the communication on game related matters.Matching together regions more advance in this field (as France,UK) with regions with less experience,the project will promote mutual learning and by mean of interreg.cooperation it will improve the effectiveness of local development policies targeting the digital+interactive media strategy.
To reach these objectives the project will:
1. Conduct a Reg.Analysis to identify the policies+the support instruments already present
2. Organize 3Study Visits for pub.authorities+
partners to regions which have already developed policies to sustain the game sector (FR, DE, UK)
3. Develop 5 Thematic Seminars (TM) for pub.authorities+project partners on relevant topics identified by the consortium.Since the games industry is facing common issues all over Europe, the TM will be an opportunity to define common solutions+learn from each other.
4. Develop a Good Practice Guide that will collect the good practices identified.It will be disseminated around Europe to allow regions not involved in the consortium to benefit from the project results
5. Organize 1 Internat.Conference in order to sensitize regions on the economic+ cultural importance of the game industry+on its growth potential 
6. Develop 1 Implementation Plan for each region to assure that the lessons learnt during the project will be integrated in the local,reg.or nat.policies
7. Implement up to 2 good practices identified in 2 regions+validate a methodology that could later be used all over Europe
(4080.01032022.211000033) VI.TA

THE PROJECT?VIACCIA TO LIVE? ARE YOU PLANNING TO BUILD TWO UNITS? HOUSING, FROM THE RECOVERY OF A BUILDING, WHICH IN THE PAST WAS USED AS OUTPATIENTS AND MANAGED BY PUBLIC ASSISTANCE. THE PROPERTY? YEAH, YEAH? ON THE PROPERTY? FROM THE COOPERATIVE, WHAT ARE YOU GOING TO DO? RESPONSIBILITY FOR THE RENOVATION AND SUBSEQUENT MANAGEMENT OF THE RENTS. THE MAIN OBJECTIVE OF THE PROJECT? TO IMPLEMENT THE SOCIAL AND STRATEGIC FUNCTIONS OF THE COOPERATIVE WITHIN THE COMMUNITY IN ORDER TO RESPOND MORE AND MORE? TO THE PROBLEMS AND EXPECTATIONS OF THE INHABITANTS OF VIACCIA. IN RECENT YEARS ARE WE WITNESSING A GRADUAL ABANDONMENT OF PERIPHERAL AREAS AND IN ORDER TO COPE WITH THIS? DOES THE COOPERATIVE INTEND TO RESPOND TO THE GROWING HOUSING EMERGENCY WITH THE CONSTRUCTION OF TWO UNITS? HOUSING, WHICH WILL BE RENTED AT CALMED PRICES, IN ORDER TO PROMOTE AND SUPPORT THE STAY WITHIN THE VILLAGE OF VIACCIA. SO, THE PROJECT AIMS TO REVITALISE THE COUNTRY’S ECONOMY THROUGH THE RENT OF
Redefining socio-environmental struggles: contributions from indigenous women from the ecuadorian amazon

AWAREFOREST proposes to study the sexual division of work in Ecuadorian Amazon, uncovering histories of struggles of indigenous women towards the advance of oil extractive activities. The objective is to understand if, and in which way gender constructions (characteristics, behaviors and gender roles) contribute to develop different perceptions and reactions between indigenous women and men with regard to the social and environmental impacts of extractivism. Through the concrete example of the Movement of Amazon Women Defenders of the Forest, this project will identify how these women are currently mobilizing and redefining meanings about their bodies and territories, based on shared reflections of personal and collective, local and global experiences of struggles for autonomy and self-determination. In terms of training and career advancement, the objectives will be to expand the researcher’s participation in academic networks, to consolidate her research profile and integration in the profession. As an early career researcher, this action will be fundamental for her integration in the European and South American research community. Benefiting from the supervision of experienced academics and the support of research groups, LEIJUS (Brazil) and EXPERICE/LADYSS (France), this will improve the researcher’s capacity to produce academic publications, take part in international events and collaborations, opening new career possibilities. AWAREFOREST innovative aspect translates into studying alternative knowledges and epistemologies, formed through socio-environmental struggles in the Amazonian context, opening up space for diverse forms of organization and views of life. It is crucial to promote these knowledges at a time when the world is facing the effects of rapid climate change and many other ecological disasters derived from a patriarchal, colonialist and capitalist form of using nature, destroying particularly indigenous territories, knowledges and societies.
53P Second-line treatment in advanced non-squamous (NS) non-small cell lung cancer (NSCLC) patients in Spain, analyzed in the Thoracic Tumor Registry (RTT)

Non-small cell lung cancer (NSCLC) accounts for the vast majority of all diagnosed lung cancers. From a histological point of view, approximately 70% to 78% of NSCLC are considered non-squamous (NS). Our analysis aimed to describe the clinical, epidemiological characteristics and survival of Spanish patients suffering from advanced NS NSCLC, treated in second line included in the RTT of the Spanish Group of Lung Cancer. 2342 patients with advanced NS NSCLC in second line were included. The median age was 67 years. 63.4 % were men. 97% of them were White. 41.7% were former smokers and 35.7% were active smokers. ECOG performance status was 0 in 32.2% and 1 in 58.7%. Most common site of metastasis was lung in 41.7%, bone in 36%, and adrenal glands in 15.6% of patients. In overall population a median progression-free survival (PFS) time of 8.1 months (4.7-13.5 m) was observed. A median overall survival (OS) time of 22.1 m (11.6-45.8 m) A total of 145 (5.8%) patients had been treated with nintedanib (N). The median PFS for patients with N treatment was 8.3 months (5.6 - 16.2 months) and for patients without was 8.1 months (4.7 - 13.5). The probability of PFS at 6, 12 and 24 m was 66.1% (64.0% - 68.0%), 29.8% (27.8% - 31.7%) and 8.2% (7.1% - 9.4%), respectively, in patients without N treatment, and 70.8% (62.4% - 77.7%), 32.8% (25.1% - 40.7%) and 11.7% (8.0% - 17.7%) in patients with N treatment. The median OS with N was 22.4 m (13.5-39.5 m) and for patients without was 22.1 m (11.6 - 45.8 m). The OS at 6, 12 and 24 m was 98.6% (94.5% - 99.6%), 80.7% (73.2% - 86.4%) and 45.5% (36.9% - 53.7%), respectively in patients with N and 93.2% (92.0% - 94.1%), 73.9% (72.0% - 75.7%), and 47.1% (44.9% - 49.3%) in patients without. The results of our analysis described the largest and most comprehensive series of NS NSCLC in the European population. Most patients included in the analysis were men and former or current smokers. The survival probability at 6, 12 and 24 months is slightly better in patients treated with nintedanib versus the overall population.
Acute pericardial effusion representing the TNF-α-mediated severe inflammation but not the coronary artery outcome of Kawasaki disease

To establish the optimal inflammation control of Kawasaki disease (KD), we investigated the clinical and pathophysiological basis of pericardial effusion (PE) during the acute phase of KD.Clinical and laboratory features of Japanese KD children with PE (PE group: n = 9) and without PE (non-PE group: n = 89) were studied retrospectively by using the medical records. Serum levels of soluble tumour necrosis factor receptor 1 (sTNFR1), interleukin 6 (IL-6), and vascular endothelial growth factor (VEGF) were assessed by enzyme-linked immunosorbent assays (ELISAs).PE group patients had coronary artery lesions (CALs) more frequently than non-PE group patients during the acute phase of KD (33% vs. 5.6%, p = 0.024). PE patients also showed lower levels of haemoglobin (p < 0.01) and serum albumin (p < 0.01) and higher platelet counts (p = 0.013) than non-PE patients. The proportion of neurological symptoms, but not other manifestations, in the PE group was higher than in the non-PE group (p = 0.022). All patients survived free from coronary artery aneurisms. Serum levels of sTNFR1, but not the other cytokines, in the PE group were higher than those in the non-PE group (p < 0.001). The sTNFR1 levels correlated positively with C-reactive protein (CRP) (r = 0.30, p = 0.019) or total bilirubin (r = 0.40, p < 0.01) levels.Acute PE in KD patients indicated the severity of TNF-mediated vascular inflammation and concurrent CALs. According to the progression, these patients might need more targeted therapy of anti-inflammation for a better coronary outcome.
Classification of Patients with Alzheimer’s Disease Based on Structural MRI Using Locally Linear Embedding (LLE)

Several methods have been used to classify patients with Alzheimer’s disease (AD) or its prodromal stage, mild cognitive impairment (MCI) from cognitive normal (CN) based on T1-weighted MRI. In this study, we used LLE to discriminate 453 subjects form the ADNI database. We conducted six pair wise classification experiments: CN (cognitive normal) vs. sMCI (MCI who kept stability and had not converted to AD within 18 months, stable MCI — sMCI), CN vs. cMCI (MCI who had converted to AD within 18 months, converters MCI — cMCI), CN vs. AD, sMCI vs. cMCI, sMCI vs. AD, and cMCI vs. AD. Each of them was repeated for 10 times. The proposed method got the average accuracy of 0.67, 0.79, 0.85, 0.72, 0.75 and 0.65, respectively. The outcomes suggested that the LLE method is useful in the clinical diagnosis and the prediction of AD.
Osteomodulin regulates diameter and alters shape of collagen fibrils

Osteomodulin (OMD) is a member of the small leucine-rich repeat proteoglycan family, which is involved in the organization of the extracellular matrix. OMD is located in bone tissue and is reportedly important for bone mineralization. However, the details of OMD function in bone formation are poorly understood. Using the baculovirus expression system, we produced recombinant human OMD and analyzed its interaction with type I collagen, which is abundant in bone. In this result, OMD directly interacted with purified immobilized collagen and OMD suppressed collagen fibril formation in a turbidity assay. Morphological analysis of collagen in the presence or absence of OMD demonstrated that OMD reduces the diameter and changes the shape of collagen fibrils. We conclude that OMD regulates the extracellular matrix during bone formation.
RIG-I-Like Receptors Evolved Adaptively in Mammals, with Parallel Evolution at LGP2 and RIG-I

RIG-I-like receptors (RLRs) are nucleic acid sensors that activate antiviral innate immune response. These molecules recognize diverse non-self RNA substrates and are antagonized by several viral inhibitors. We performed an evolutionary analysis of RLR genes (RIG-I, MDA5, and LGP2) in mammals. Results indicated that purifying selection had a dominant role in driving the evolution of RLRs. However, application of maximum-likelihood analyses identified several positions that evolved adaptively. Positively selected sites are located in all domains of MDA5 and RIG-I, whereas in LGP2 they are confined to the helicase domain. In both MDA5 and RIG-I, the linkers separating the caspase activation and recruitment domain and the helicase domain represented preferential targets of positive selection. Independent selective events in RIG-I and LGP2 targeted the corresponding site (Asp421 and Asp179, respectively) within a protruding α-helix that grips the V-shaped structure formed by the pincer. Most of the positively selected sites in MDA5 are in regions unique to this RLR, including a characteristic insertion within the helicase domain. Additional selected sites are located at the contact interface between MDA5 monomers, in spatial proximity to a positively selected human polymorphism (Arg843His) and immediately external to the parainfluenza virus 5 V protein binding region. Structural analyses suggested that the positively selected His834 residue is involved in parainfluenza virus 5 V protein binding. Data herein suggest that RLRs have been engaged in host-virus genetic conflict leading to diversifying selection and indicate parallel evolution at the same site in RIG-I and LGP2, a position likely to be of central importance in antiviral responses.
Thermodynamic kernel, IMEP, and response based on three plasma energies

The key element of this work is that it consists of experiments and simulations concerned with kernel characteristics, secondary plasma signal, IMEP performance, and combustion response, making use of MEHV (matching effect of high voltage) in order to increase thermodynamic combustion energy. This system, involving three plasma models, tanks, mixtures, mass flow controllers, regulators, coils, a high-speed camera and plugs, was designed by Labview software. The jet plasma model was verified as having characteristics increased greatly up to 39.8 kV of the surge voltage amplified by the transformer, from (-)0.11 ms to 0 ms and the jet plasma discharge was verified as having double characteristics increased to 32 kV primary and 8 kV secondary between 0 ms and 1 ms. Consequently, the IMEP performance analyzed by these experiments and simulations was notable in that it was demonstrated that the plasma energies could be promoted significantly and quickly to create a thermochemical reaction in the order of spark < arc < jet model in a chamber, and the plasma energies were shown to be predictable in that FCR (fuel consumption rate) could demonstrably be improved in a chamber.
Gauging the risk of incidents of extremist violence against non-combatant entities

GRIEVANCE seeks to make significant advances in increasing our understanding, and thereby reducing the risk, of extremist violence against non-combatants. An inter-disciplinary project underpinned by crime prevention principles is needed to help quantify the risk of such offences. The barbarity of such violent acts, coupled with the fact that participation in them is characterised by an extremely low base rate, has led researchers to seek out individual qualities of the offender with a particular focus upon what radicalisation is and how its drivers can be countered. This search has proven unproductive and impractical. In fact, it has most likely limited and unduly narrowed a wider consideration of the ways in which social scientists can bring what conceptual tools we have to bear on the problem of controlling and managing such behaviour. By doing so, this project shifts the focus from individual qualities (what we think terrorists and other similar offenders “are”) to a consideration of the situational qualities of their behaviour – in other words, what violent offenders do and how they do it (Horgan, 2009: 143). This is consistent with developments in the area of crime control (Cornish and Clarke, 1986; Brantingham & Brantingham, 1981) and crime science more generally. More specifically, GRIEVANCE will utilise a number of unique datasets to understand the risk of extremist violence across a number of phases of analysis. GRIEVANCE characterises risk in terms of a process and dedicates a work package (WP) to each stage of the process from the risk of radicalisation (WP1), to the risk of recruitment (WP2), to the risk of violent action (WP3), to the temporal (WP4) and spatial (WP5) risk of offending behaviour followed by an assessment of the risk of adverse consequences from intervention (WP6). GRIEVANCE will both synthesise the existing knowledge within the literature and produce innovative new findings by utilising cutting edge inter-disciplinary research methods.
Quantitative computational screening of Pd-based intermetallic membranes for hydrogen separation

One of the most important processes in producing high purity hydrogen is separating hydrogen from a mixture of gas streams. This work looks at intermetallics, stoichiometric compounds of two or more metals, as prospective membranes for these applications. We describe a systematic computational screening approach based on calculation of key properties like solubility, diffusivity and permeability of hydrogen through these materials using quantitatively accurate Density Functional Theory calculations. Solubility was used as a screening parameter and solubility data has been calculated for 78 Pd-based binary intermetallics. Permeability calculations were performed for the shortlisted candidates. After systematically examining all Pd-based intermetallics, no material was found to have higher hydrogen permeability than pure Pd. To investigate the potential influence of hydrogen on the stability of metastable phases, we examined a number of metastable structures of Pd 3 Mn. Two metastable Pd 3 Mn phases are stabilized in the presence of hydrogen, but these phases are predicted to have low permeability. We also explored whether an empirical relationship could be found to rapidly predict H solubility in intermetallics using a QSPR approach. Unfortunately, the values calculated using this empirical approach cannot be used to make useful predictions. • Computational screening was used to predict H permeability through intermetallics. • H permeability of 78 Pd-based d-block binary intermetallics was calculated. • No intermetallic was found to have H permeability higher than that of pure Pd. • H was found to stabilize the metastable phases of Pd 3 Mn.
SYSTEM DESIGNED FOR THE ACQUISITION OF VOLCANIC SEISMICITY

This work presents a system created for the acquisition of volcanic seismicity. In order to prevent the danger of a volcanic eruption, volcanoes are monitored to determine the state on which they are. One of these parameters is the seismicity generated by the movement of ground. To monitoring this parameter, it is been created a low cost and low power system mounted in a waterproof case to be installed in hard environments with adverse conditions. It is an autonomous system built to be used in long- term campaigns. This equipment incorporates a low power microprocessor as the core of the system, three acquisition channels and a GPS to synchronize the time base. Data can be stored in a SD memory or it can be sent remotely via radio-frequency. The final tests show a correct acquisition of the system with an event produced in the Canary Islands.
Toward a Near Real-Time Product of Air Temperature Maps from Satellite Data and In Situ Measurements in Arid Environments

Earth observation data and in situ measurements were used to derive a method for the estimation of Air Temperature(AirT) and thereby produce maps. The methodology was developed and validated using data acquired at five stations located in the United Arab Emirates(UAE) during the year 2012. In the first step, the effect of different variables on the estimation of AirT values was investigated and the variables of high importance were used to build the final model. Land surface temperature (LST), relative humidity, global horizontal irradiance, direct normal irradiance, and diffuse horizontal irradiance were identified as the most important inputs for Air Testimation. Models were developed separately for four different cases based on the seasons (Winter/Summer) and the time of the day (Day/Night). The models were evaluated using jackknife validation on the stations resulting in root mean square errors of 2.25°C(Winter/Day), 2.24°C (Winter/Night), 2.56°C (Summer/Day), and 2.69°C (Summer/Night) and an overall average accuracy of 2.44°C. Finally, the model has been applied on a larger scale by assimilating the relevant Earth observation data and in situ measurements for the creation of AirT maps for the entire country. The resulting AirT maps were generated in near real time at a temporal resolution of 15 min from METEOSAT/SEVIRI LST and the above-mentioned in situ measurements. These maps can be considered as important resources for several applications (e.g, climate studies, solar energy applications, thermal comfort studies, etc.).
Edges in Agricultural Landscapes: Species Interactions and Movement of Natural Enemies

Agricultural landscapes can be characterized as a mosaic of habitat patches interspersed with hostile matrix, or as a gradient of patches ranging from suitable to unsuitable for different species. Arthropods moving through these landscapes encounter a range of edges, with different permeability. Patches of native vegetation in these landscapes may support natural enemies of crop pests by providing alternate hosts for parasitic wasps and/or acting as a source for predatory insects. We test this by quantifying species interactions and measuring movement across different edge-types. A high diversity of parasitoid species used hosts in the native vegetation patches, however we recorded few instances of the same parasitoid species using hosts in both the native vegetation and the crop (canola). However, we did find overall greater densities of parasitoids moving from native vegetation into the crop. Of the parasitoid groups examined, parasitoids of aphids (Braconidae: Aphidiinae) frequently moved from native vegetation into canola. In contrast, parasitoids of caterpillars (Braconidae: Microgastrinae) moved commonly from cereal fields into canola. Late season samples showed both aphids and parasitoids moving frequently out of native vegetation, in contrast predators moved less commonly from native vegetation (across the whole season). The season-long net advantage or disadvantage of native vegetation for pest control services is therefore difficult to evaluate. It appears that the different edge-types alter movement patterns of natural enemies more so than herbivorous pest species, and this may impact pest control services.