SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Structurally informed design of masonry assemblages composed of interlocking blocks

Masonry benefits contemporary architecture regarding sustainability and application to free-form construction. A masonry structure can be considered as an assemblage of conventional or interlocking rigid blocks with frictional joints. Although interlocking blocks’ resistance to sliding is higher and their construction is easier when compared to conventional blocks, there is no digital framework to design structurally-sound assemblages composed of interlocking blocks with diverse typologies. Therefore, I intend to develop a digital framework that supports designers in the design of structurally feasible and assemblable masonry assemblages of interlocking blocks. The framework will accomplish the following:
-it allows designers to model an assemblage and to analyze its structural feasibility;
-for the structurally infeasible model, it will automatically modify the geometry of the interlocking blocks’ connectors, making the model structurally feasible; 
-during the geometric modification, it will avoid geometries which do not construct the assemblable blocks. 
To evaluate the structural feasibility, a novel experimental method will equate the frictional resistance of the corrugated face of an interlocking block to that of the flat face of an equivalent conventional block. I also propose an extension of the limit analysis method, in which block resistance to sliding is different in different directions, and plan to use equations from the experimental method.
The project is an interdisciplinary research in the fields of architectural, computational and structural design and will train skills helping to establish me as a researcher leading studies on structurally informed architectural design as well as to become an entrepreneurial architect who uses masonry in contemporary architecture. It will also create opportunities for host organizations to collaborate with architectural academia and manufacturing industry in the field of integrated architectural-structural design.
SOVVENZIONE PER IL CAPITALE CIRCOLANTE

Il progetto riguarda il sostegno dell'imprenditore nel fornire liquidità finanziaria e il sostegno alle attività in corso a causa delle difficoltà finanziarie incontrate dall'imprenditore a causa dell'epidemia di COVID-19. Assistenza finanziaria erogata nell'ambito del programma n. SA.57015 (2020/N)
SYNTHESIS OF METAL OXIDES BY REACTIVE CATHODIC ARC EVAPORATION

This application relates to the reactive cathodic arc evaporation of the composite Al-Cr targets and the nucleation and phase formation of the synthesized Al-Cr-O layers. The oxygen partial pressure and the pulsed operation of the arc current influence the formation of intermetallic phases and solid solutions at the target surface. The nucleation of the ternary oxides at the substrate site appears to be, to some extent, controllable by the intermetallics or solid solutions formed at the target surface. A specific nucleation process at substrate site can therefore be induced by the free choice of target composition in combination with the partial pressure of the oxygen reactive gas. It also allows the control over the oxide island growth at the target surface which occurs occasionally at higher oxygen partial pressure. This is supported by the X-ray diffraction analysis of the layers as well as of the target surface.
Gender Differences and Predictors of Mortality in Takotsubo Cardiomyopathy: Analysis from the National Inpatient Sample 2009-2010 Database

&lt;b&gt;&lt;i&gt;Objectives:&lt;/i&gt;&lt;/b&gt; Takotsubo cardiomyopathy (TC) is characterized by left-ventricle apical ballooning with elevated cardiac biomarkers and electrocardiographic changes similar to an acute coronary syndrome. We studied the prevalence, in-hospital mortality, and predictors of mortality in TC. &lt;b&gt;&lt;i&gt;Methods:&lt;/i&gt;&lt;/b&gt; All patients ≥18 years of age diagnosed with TC were identified in the Nationwide Inpatient Sample (NIS) 2009-2010 database using the 9th revision of the International Classification of Diseases (ICD) 429.83. Demographics, conventional risk factors (diabetes, hypertension, hyperlipidemia, and tobacco abuse), acute critical illnesses like sepsis, acute cerebrovascular disease (cerebrovascular accident; CVA), acute respiratory insufficiency, and acute renal failure, and chronic conditions (anxiety, depression, and malignancy) were studied. &lt;b&gt;&lt;i&gt;Results:&lt;/i&gt;&lt;/b&gt; The prevalence of TC was 0.02% (n = 7,510). The total in-hospital mortality rate was 2.4%, with a higher mortality in men (4.8%) than in women (2.1%). Sepsis (9 vs. 4.2%; p &lt; 0.01) was more prevalent in men with an increased prevalence of other critical illness, although this was not statistically significant. Age (OR 1.05; 95% CI 1.01-1.09), malignancy (OR 3.38; 95% CI 1.35-8.41), acute renal failure (OR 5.4; 95% CI 2.2-13.7), acute CVA (OR 9.4; 95% CI 2.96-29.8), and acute respiratory failure (OR 11.1; 95% CI 3.9-31.1) predicted mortality in fully adjusted models. &lt;b&gt;&lt;i&gt;Conclusion:&lt;/i&gt;&lt;/b&gt; A higher mortality was seen in men, likely related to the increased prevalence of acute critical illnesses, ventricular arrhythmia, and sudden cardiac arrest. Acute CVA and respiratory failure were the strongest predictors of mortality.
MODULAR IN LINE BUTTON DRIP EMITTER SYSTEM

A modular in-line drip emitter may include a flow restrictor and a replaceable attachment. The flow restrictor may provide fluid communication between an inlet and a fluid outlet chamber. The flow restrictor may include rate limiting fluid path producing a predefined range of flow rate over a predefined pressure differential range between the fluid inlet and the fluid outlet. The attachment may be sized and shaped to mount to the flow restrictor. In some embodiments the attachment includes an inlet opening oriented for receiving fluid from a conduit and a fluid outlet attachable to the fluid inlet of the flow restrictor. In some embodiments the attachment includes a sleeve fitting into a conduit with an annular outlet chamber attachable to the outlet chamber of the flow restrictor.
POLYNUCLEOTIDE ENCODING A NOVEL HUMAN P2X7 SPLICE VARIANT, HBMYP2X7V

The present invention provides novel polynucleotides encoding HBMYP2X7v polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel HBMYP2X7v polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
WIND POWER PLANT

A semi-submersible wind power platform includes a tower and a plurality of arms for stabilizing the tower, each arm having a float experiencing an anchoring force. Each arm consists of two elongated elements forming with part of the tower a triangle, and at least one of the elongated elements includes a catenary element.
(14508.17092020.172000393) PALAI

C’EST ÇA? L’IDÉE DE PROJET COUVERTE PAR L’INITIATIVE CONSISTE EN? L’ACHAT D’UNE CABINE DE PEINTURE AU SERVICE DU CAMION SERA ÉGALEMENT ACHETÉ MATÉRIEL ET LOGICIEL POUR LA GESTION ADMINISTRATIVE DE L’ENTREPRISE.
IL-21 AS A REGULATOR OF IMMUNOGLOBIN PRODUCTION

A transgenic mouse is disclosed herein whose somatic and germ cells comprise a disrupted IL-21 receptor gene, the disruption being sufficient to inhibit the binding of IL-21 to an IL-21 receptor, and a disrupted IL-4 receptor gene, the disruption being sufficient to inhibit the production of IL-4 or the binding of IL-4 to the IL-4 receptor. A mouse homozygous for the disrupted IL-21 receptor gene and homozygous for the disrupted IL-4 gene has diminished B cell function. A method is disclosed for altering a B cell activity. The method includes administering a therapeutically effective amount of an agent that interferes with the interaction of IL-21 with an IL-21 receptor, thereby altering the B cell activity. A method is also disclosed for of treating a subject with Job's disorder or atopic disease. A method is also disclosed for treating or preventing an allergic reaction in a subject.
Neogenesis of new functional beta cells through modulation of neurogenin-3 expression to provide regenerative therapy for diabetes patients

Diabetes mellitus is a chronic metabolic disorder characterized by elevated blood sugar levels with increased risk of cardiovascular complications. The currently available therapy for type 1 diabetes (TIDM) consists of daily injections of exogenous insulin in order to delay disease progression. However, these treatments do not provide a real cure since long-term secondary complications cannot be avoided. As TIDM is characterized by the highly specific immune-mediated destruction of one cell type, this disease represents a particularly ideal candidate for cell replacement therapy. Transplantation of human islets, isolated from cadaveric donor pancreas, potentially represents a genuine cure for TIDM but is limited by a shortage of transplantable islets. 
In the current application I will create an unprecedented humanized mouse model to test pharmacological therapies for diabetes. In a first step I will study the actions of Geminin on the regulation of the pro-endocrine transcription factor Neurogenin3 during mouse and human development and postnatal beta cell regeneration from the exocrine cells of the pancreas. These experiments will provide tools to control Neurogenin3 expression and thus endocrine cell differentiation in the human pancreas. Using the knowledge gained from in vivo mouse studies, I will create a novel clinically relevant humanized mouse model. I will use this model to develop a cytokine-based treatment to convert human acinar cells to functional beta-like cells in a Neurogenin3 dependent way. Finally, I will design a strategy to deliver the pro-endocrine treatment in a cell-specific manner. The humanized model will serve as a unique platform to test treatment for human diabetes in the pre-clinical phase.
This project utilizes a multidisciplinary approach to develop a strategy based on pharmacological treatment rather than cell therapy, paving the way for clinical application.
Self-managed content-based routing for opportunistic networks

Several countries such as Uruguay and Brazil are implementing the well-known One Laptop Per Child Program (OLPC) by which every child that assists to the primary school obtains in property a laptop with wireless capabilities. They carry their laptops from home to school and back every day and, as seen in the experience, they also carry their laptops to parks, community centers etc. This provides a wide platform for the deployment of Disruption Tolerant network applications. This paper presents a self-managed, opportunistic and content-based routing protocol that supports a network of environmental sensors implemented using consumer-grade wireless routers working together with OLPC laptops. We evaluate the impact of the density, diversity and connectivity of the mobile network on the performance of the protocol and we show how it self-configures it parameters to adapt to changing network conditions.
Architectural Restoration: a comparison between Japan and Italy

The restoration of architecture in a nation is a project strictly connected to its culture, its society, as well as to the weather conditions and to its political and economic background. The contemporary culture, in particular, has developed an awareness of the fact that the main pur-pose of the conservation of monuments and landscape is not only protecting the matter of social well but also its intrinsic values, strongly connected to the sense of belonging to the place. The necessity of searching these values comes from the need of knowledge of the different cultural references that permit to man to direct his choices as concerns conservation and safeguard compared to popular areas of interest apparently of less importance but vivid from the cultural and social point of view. And this is the birth of the relationship between values and needs connected to the demand of transformation of urban and housing contexts. On these as-sumptions the book Twelve houses restored in Japan and Italy focuses on restoration projects of historical urban contexts, where the theme of living produced changes, influenced different intervention methods and functional choices without changing the sign of history. The book wants to introduce restoration projects comparing different cultural realities and architectonical methods that characterized the present situation in Italy and Japan. The experiences described in the book notice an interesting sharing among the different methods of restoration.
Adolescent childbearing experiences in Kenya : geographical and socioeconomic determinants

Sub-Saharan Africa has one of the highest level of teenage pregnancies in the world. Some studies on this topic highlight the presence of unmet reproductive health needs of adolescent in different regions. Improving maternal health has been established as a key development priority among the Millennium Development Goals, and upgrading reproductive and maternal health is usually associated with the eradication of inequality and poverty and with the presence of health care programs and services devoted to girls’ education. We attempt to investigate the geographical and socioeconomic determinants of both teenage pregnancies and maternal health behaviours among adolescent women in Kenya. We ascertain the influence of the availability of health care facilities mainly oriented to the specific needs of reproductive health. Main data are represented by 2003 Kenyan Demographic and Health Survey. In addition, the DHS data set collects Global Positioning System locators for each of the primary sampling units included in the samples that enable a deep geographical analysis. We perform a multivariate multilevel analysis to estimate the influence that individual, household, and community-level factors have on the risk of adolescent childbearing. Additionally, a spatial component allows for the presence and proximity of maternal health services. We expect that the availability of reproductive health facilities acts together with levels of socio-economic development, individual and household characteristics and community fertility norms, in influencing individual reproductive behavior at very young ages.
SMES IN DEVELOPED AND DEVELOPING COUNTRIES TREADING SIMILAR PATHS TOWARDS ETRANSFORMATION

The global economy has become increasingly reliant on Information and Communication Technology (ICT) toolsand systems to process and exchange information. The Small and Medium Enterprises (SMEs) are yet to reap these benefits as obtaining such opportunities rests on their ability to integrate ICT into business tasks and processes. They need to transform their companies by implementing appropriate ICT in order to compete within a busy digital economy. The aim of this study was to see how SMEs from developed and developing countries follow their eTransformation journey and also to identify the differences and similarities businesses encounter in that process. Our research confirms that the eTransformation takes place as an incremental process for both groups and that the eTransformation pattern is similar in both worlds. However, we notice that in Australia, a developed country, SMEs are more aware of eTransformation and are demanded by customers and digital economy to change, where as in Sri Lanka eTransformation is still in its early stages of development.
Dyslipidaemia in Newly Diagnosed Diabetic Patients with and without Microalbuminuria

Objective: To determine the association of dyslipidemia in newly diagnosed diabetic patients with and without microalbuminuria.
Study Design: Cross sectional study.
Place and Duration of Study: The study was conducted from December 2009 to July 2011 at Medical Unit 1, Pakistan Railway Hospital, Islamic International Medical College (IIMC) Rawalpindi.
Materials and Methods: A cross sectional study was carried out in Medical Unit 1 Pakistan Railway Hospital Rawalpindi. The newly diagnosed diabetic patients i.e. the patients who have not yet been given any treatment, of both genders, without overt-proteinuria were included in the study. A proforma was filled indicating their bio-data, history and clinical examination and laboratory investigations which included fasting blood glucose, urinary albumin and lipid profile. If albumin was negative with dipstick, a sample of urine was sent for microalbuminuria. Frequency of dyslipidaemia in patients with and without microalbuminuria was determined.
Results: Out of the 317 newly diagnosed diabetic patients screened for microalbuminuria, 43 patients (13.5%) had microalbuminuria while 274 patients (86.6%) did not have microalbuminuria. Out of these patients with microalbuminuria, 58.8% (i.e 24) of patients had dyslipidaemia. Among microalbuminuria negative patients only 36% (i.e101) of patients had dyslipidaemia.
Conclusion: The dyslipidemia, occurs more frequently in newly diagnosed diabetics who have micro-albuminuria than those without micro-albuminuria.
Mario Isnenghi. <i>Vite vissute e no. I luoghi della mia memoria</i>

Recensione di: Isnenghi, M. (2020). Vite vissute e no. I luoghi della mia memoria . Bologna: il Mulino, 327 pp.
BATTERY CHARGER

Female guide portions for slidingly attaching a battery pack are formed by integral molding of a case main body. Exposed step portions are formed on the female guide portions, which includes protruding portions as thin-walled portions by application from the outer side (the upper side) of a mold so as to reduce the thickness of a thick-walled resin portion. An opening communicating with the inner and outer side of the case is not provided, while the protruding portions are formed as thin-walled portions. Bottom surfaces of the exposed step portions are formed so as to be sloped with respect to the horizontal direction when the battery charger is placed on a horizontal base, and water dropped on the bottom surfaces can flow outside of the case due to the slope without remaining thereon.
A Simulation Study of Logistics for Disaster Relief Operations

Abstract Natural events, climate change and urbanization are pushing the pressure on disaster relief operations. Decision science and ICT technologies can be effectively used to face humanitarian logistics issues. This concerns both man-made threats (accidents) and natural hazards such as e.g. floods, storms, earthquakes and volcanic eruptions. The purpose of this paper is to analyse the operation strategies for rescue in emergency situations deployed by specialized rescue teams. Usually standard procedures are applied for rescue operations. These procedures can fail in disaster relief situations where an abnormal number of rescue operations are to be fulfilled. It is important to study mechanisms able to give more flexibility to these procedures and to study the effectiveness of the procedures in planning phase. At this aim we used discrete event simulation as decision support for planning different strategies of action to apply in emergency and risk situations. In particular several scenarios have been developed as simulation models combining different initial hypothesis with the aim to build a generalized and flexible procedure to apply in different scenarios. As a result, the simulation is able to allocate efficiently different resources under emergency situations (multiple scenarios for specific events). Tests and sensitivity analysis have been performed using instances related to a GIS of the Italian Sicily region and a typical set of facilities and rescue team. The simulation system works considering the different typologies of vehicles and staff to choose the best solution available in that specific time. The work is part of a national research project aimed to develop cloud-based systems and sensor networks for multi-risk management. The developed simulation system can provide crucial help to the rescuers in order to planning the best relief strategy for mitigate the effects of natural and industrial disasters.
Effects of LI-4 and SP-6 Acupuncture on Labor Pain, Cortisol Level and Duration of Labor

Nowadays, acupuncture is widely used to manage pain, and childbirth is a condition requiring appropriate pain management interventions. The efficacy of acupuncture in the management of labor pain has recently been studied, but the results are not satisfactory and conflicts exist. In this study, we investigated the effects of acupuncture on labor pain, serum cortisol level, and duration of labor. We conducted a randomized, single-blind, controlled trial that included 63 nulliparous women: 32 in the study group and 31 in the control group. Acupuncture was performed at the SP-6 and the LI-4 points in the study group, and sham acupuncture was performed at the same points in the control group. Pain scores and serum cortisol levels were measured before and after the intervention. Changes in these measures and in the duration of labor were compared between the groups. No significant variations in pain scores or serum cortisol levels were observed between the two control groups. However, the duration of labor was significantly lower (p < 0.001) in the group receiving real acupuncture. Our results show that acupuncture is significantly associated with a decreased duration of labor, even though it was no better than a placebo for the treatment of labor pain.
(12057.23072018.127000003) INTERNATIONALISATION FIFTH EGO — STEP 1

THE CONSTANT CRISIS THAT HAS BEEN AFFECTING THE ITALIAN DOMESTIC MARKET SINCE 2008 IS S? WHAT DO YOU NEED? OF A PROCESS OF INTERNATIONALISATION OF COMPANIES, AS A STRATEGIC ELEMENT FOR INTEGRATION AND COMPETITIVENESS? OF ITALIAN COMPANIES, DON'T THEY? ARE MICRO-ENTERPRISES CHARACTERISED BY A CHRONIC SHORTAGE OF HUMAN RESOURCES AND ECONOMIC AND FINANCIAL RESOURCES AS WELL AS? AN INADEQUATE CULTURE OF INTERNATIONALISATION. DESIGNING AN INTERNATIONALISATION PROCESS INVOLVES, FOR THE COMPANY, CONSIDERABLE COSTS AIMED AT SUPPORTING MARKET RESEARCH AND STRATEGIES, PROVIDING FOR RESTRUCTURING, SOMETIMES EVEN TOTAL, IN THE PRODUCTION, LOGISTICS AND COMMERCIAL ORGANISATION. DOES THE CHRONIC WEAKNESS OF SMALL AND MICRO-ENTERPRISES LEAD TO POOR FAMILIARITY? WITH ORGANIZATIONAL MANAGEMENT TOOLS THAT ARE INDISPENSABLE TO ADDRESS COMPLEXITIES? THE CHALLENGE ON THE GL MARKET
Random Simulation Method for the PERT Network Based on the CrystalBall and Excel Environment

Although Program Evaluation and Review Technique(PERT) has been applied widely in the planning and control of the project progress, there are some deficiencies, for example, the accuracy of the estimated activity duration is not high, the distribution pattern of the duration variable is single, the calculation result of the project completion probability is slightly larger and so on. Based on present research results, this article proposes using Monte Carlo simulation method to simulate varieties of distribution situations of the activity duration with Crystal Ball and Excel tools, and calculate the completion time and the probability distribution of the project according to the Critical Path Method(CPM). In the last, this article verifies the effectiveness and the convenience of this method by an example. Because of abandoning assumptions of the PERT, therefore the random simulation model has more stronger adaptability and credibility than the traditional PERT. Taking advantage of Crystal Ball and Excel tools, the project progress managers can easily realize the random simulation and calculation of the large-scale complex projects, then guarantee the successful completion of the project and reduce the risk of duration delay.