SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
An Aristotelian investigation into personal training.

Based on an Aristotelian analysis this research defines a Personal Trainer as a form of coach who isrationally and emotionally balanced, who can apply their practical wisdomflexibly to develop a relationship with their client enabling them to behealthier, fitter and happier. Research looking at 5 key texts books recommendedinternationally to study to become a Personal Trainer shows that on average 53%of the text is devoted to technical knowledge; 39% to scientific knowledge andonly 9% to psychology & motivation. It is concluded there is need for a shift in thedefinition and perception of Personal Training practice so that it encompassesmore thoroughly and in balance all three of Aristotle’s virtuous knowledges:the episteme, the techne and the phronesis.
Localized targeted therapy to avoid recurrent glioblastoma multiforme

TargTex is a newly founded Portuguese startup with a novel concept to tackle the most lethal type of brain tumor – Glioblastoma Multiforme (GBM).
GBM is the most common and aggressive type of primary brain tumor, with a survival rate lower than 5% after 2 years. The aggressiveness of the disease combined with the lack of effective treatments translates into a terrible prognosis to GBM patients, with a life expectancy of no more than 12 to 18 months after being diagnosed.
TargTex team has developed a concerted approach, taking into consideration the needs and contributions from key stakeholders: patients, doctors and scientists.
This innovative treatment (for which we have IP protecting the application) is based on a hydrogel formulation to be used as adjunct to surgery, applied after tumor resection. With a slow release from the hydrogel – over several weeks – the molecule is able to selectively kill GBM tumor cells that were not fully removed during surgery, thus offering a safer solution to neurosurgeons, who often deal with the conundrum of removing unaffected brain tissue to avoid tumor recurrence. In addition, this approach brings added benefits to the patients since the single treatment does not require further chemotherapy cycles.
Most importantly, the active drug is a small molecule that binds to a specific target in GBM cells, and therefore, covers the whole patient population since it is not a personalized medicine. 
Our goal for the Phase 1 is to assess the technical, commercial and financial feasibility of TargTex.
For that purpose, we will a) assess the regulatory framework and IP strategy to develop an adjunct to surgery in the context of GBM; 2) design the Toxicology & Safety Pharmacology experiments needed for an EMA’s Clinical Trial application; 3) assess the willingness to adoption of our solution from neuro-oncologists and neurosurgeons and 4) evaluate competition and assess the interest of investors and pharma towards our unique product.
Prospective Association between Dietary Fiber Intake and Breast Cancer Risk

Mechanistic hypotheses suggest a potential effect of dietary fiber on breast carcinogenesis through the modulation of insulin-like growth factor bioactivity, estrogen metabolism and inflammation. An association between dietary fiber intake and breast cancer risk has been suggested in epidemiological studies but remains inconclusive. In particular, data is lacking regarding the different types of dietary fibers.The objective was to investigate the prospective relationship between dietary fiber intake and breast cancer risk, taking into account different types of dietary fiber (overall, insoluble, soluble and from different food sources: cereals, vegetables, fruits and legumes).4684 women from the SU.VI.MAX cohort were included in this analysis as they completed at least three 24h-dietary records within the first two years of follow-up. Among them, 167 incident invasive breast cancers were diagnosed during a median follow-up of 12.6 years (between 1994 and 2007). The associations between quartiles of dietary fiber intake and breast cancer risk were characterized using multivariate Cox proportional hazards models.Total fiber intake was not associated with breast cancer risk (HR(Quartile4vs.Quartile1) = 1.29 (95%CI 0.66-2.50), P-trend = 0.5), nor was fiber intake from cereals (P-trend = 0.1), fruits (P-trend = 0.9) and legumes (P-trend = 0.3). In contrast, vegetable fiber intake was related to a decreased risk of breast cancer (HR(Q4vs.Q1) = 0.50 (0.29-0.88), P-trend = 0.03). Overall vegetable intake (in g/day) was not associated with breast cancer risk (P-trend = 0.2).This prospective study suggests that vegetable fiber intake may contribute to reduce breast cancer risk, in line with experimental mechanistic data.
The empress's route - Cultural and flavour itineraries between Veneto, Friuli and Slovenia

This initiative is going to carry out integrated actions to promote and enhance the cultural and historical traditions, and the typical productions of the whole Programme-area, in order to foster the development of tourism and of the other economic resources in the territory. The project aims at drawing an ideal line, in keeping with the tradition of the ancient courts of Europe, and especially of the Serenissima Republic and the Hapsburg imperial court, in a historical context going from the 18th to the 20th century, and characterized by dramatic economic and social changes. The territory under examination, located between Veneto, Friuli Venezia Giulia and Slovenia, is endowed with a very rich historical, naturalistic and architectural heritage. In this regard, the project is going to foster the enhancement of these resources as well as of other economic resources, to increase tourism through a concerted system of communication and promotion, whose core has been detected in the “Empress’s route”. For a virtual tour, please browse through the above-mentioned web site. The cultural relevance of this initiative makes it possible to support the rural development of the partner areas. Wine is a niche product and is therefore the best expression of culture, tradition and history of the whole territory. Centred on the world of wine production, some tourist packages will be devised and will be within their full rights to enter the national and international tourist circuits.
The problematic C2H4+F2 reaction barrier

The C(2)H(4)+F(2) reaction is investigated through the most rigorous electronic structure methods currently feasible, using a focal point approach to converge toward the ab initio limit. Explicit computations were executed with basis sets as large as aug-cc-pV5Z and correlation treatments as extensive as coupled cluster through full triples with a perturbative inclusion of quadruple excitations [CCSDT(Q)]. Auxiliary core correlation, diagonal Born-Oppenheimer, and first-order relativistic corrections were included. All optimized geometries and vibrational frequencies were determined completely at the CCSD(T)/aug-cc-pVQZ level. The final C(2)H(4)+F(2) reaction barrier from theory (8.0 kcal mol(-1)) is significantly higher than the recently reported experimental barrier (5.5+/-0.5 kcal mol(-1)). Our computations also yield a new enthalpy of formation of the fluoroethyl radical, Delta(f)H(298) degrees(C(2)H(4)F)=-13.2+/-0.2 kcal mol(-1), whose uncertainty is an order of magnitude less than previous experimental values.
A flexible, data-driven model framework to predict soil responses to land-use and climate change

Soil organic matter is the largest land carbon (C) pool, vulnerable to land-use change and climate change. Soil C models are used to assess current organic C stocks and make predictions under future conditions. These models are typically developed to make predictions over centennial timescales. Given the ‘4 per mil’ initiative, there is now a critical need for annual-to-decadal soil C stock predictions to evaluate land management decisions and hold participants accountable to stated goals. The project proposes a new soil model framework to make predictions at annual-to-decadal timescales by developing a Bayesian forecasting model from a deterministic soil carbon model with the capacity to ingest multiple data types, propagate uncertainty from data and parameters into predictions, and update predictions when new data become available. The main focus is probabilistic prediction of soil C changes under land use and climate change for the next two decades. Specifically, the project plans build a forecasting model version of the Millennial model, recently developed by the researcher with University colleagues. The Millennial model is an evolution of the commonly used soil C model Century – also incorporated in the global land surface model (ORCHIDEE) of the host institution (LSCE) - but in contrast to Century, Millennial includes soil pools that correspond directly to measurements. First, we will develop the Bayesian calibration of modeled temperature response against warming experiment data, using the Millennial model to integrate measurements from the multi-national, collaborative whole-soil warming experiments FORHOT and BBSFA. Then, we will develop the Bayesian calibration of the modeled land management response against field data with different amounts and quality of added litter. We will then incorporate this new model into ORCHIDEE to predict soil C storage for near term land-based mitigation objectives of the Paris Climate Agreement.
High school teacher development workshops that create long-term student impact

Increasing the number of STEM graduates is critical to our nation's future. High school teachers play an essential role in accomplishing this goal by preparing and encouraging students to pursue STEM fields in college. This paper describes a series of workshops, referred to as TechSTEP, that focus on equipping teachers with tools, techniques, and skills they can immediately implement in their classrooms so as to better prepare students to successfully pursue STEM degrees. The specific workshop described in this paper involves building prototype fuel cell vehicles. In addition to the science of fuel cells and the engineering involved in vehicle design, the project also incorporates a model for natural resource depletion and includes other related economic, environmental, social, and political issues. The ultimate goal of TechSTEP is to increase the number of students successfully pursuing STEM degrees at the university. Even though TechSTEP includes high school students, the primary focus is on high school teachers. We believe long-term impact is more likely to result from the interactions and relationships developed with these teachers. On average, there has been a 39% increase in the number of students enrolling in STEM majors at Louisiana Tech University from schools participating in TechSTEP.
Improvements in thread carrier driving mechanism for straight bar knitting machines

673,979. Knitting. COLTON, L. H. (Thiede, W.). July 8, 1949, No. 18043/49. Class 74 (ii). A straight-bar knitting-machine has a positive thread carrier drive, providing a substantially constant lead of the thread carrier or carriers in front of the slurcock, in which a coupling device for engaging and disengaging a thread carrier rod to and from the slurcock bar comprises an element movable along a cycloidal path during engagement to achieve substantially shock-free acceleration of the thread carrier rod at the commencement of its travel and movable along a cycloidal path during disengagement to achieve substantially shock-free retardation of the thread carrier rod at the end of its travel. As slur bar 1 begins to move to the left, pinion 7, which is carried with it, rolls along rack 15 and is rotated clockwise through 90 degrees. During this rotation, roller 6 enters behind member 9 and moves thread carrier rod 2 with increasing speed until, when crank-arm 5 is horizontal, bar 2 is moving at the same speed as bar 1. Towards the end of the traverse, pinion 7 engages rack 16 and is rotated through a further 90 degrees to release member 9 by means of a bar 24. Rack pairs 15-17 and 16-18 are now raised whilst the slurcock is stationary, so that, as the reverse traverse begins, pinion 7 rolls along rack 18 through a third 90 degrees to enter pin 6 behind member 11 and accelerate rod 2 up to full speed and, as the traverse is ending, rolls along rack 17, through a final 90 degrees to disengage pin 6. Racks 15, 17 and 16, 18 are moved, during widening or narrowing, by means of rods 26, 27.
A 64-channel 3T array coil for accelerated brain MRI

A 64-channel brain array coil was developed and compared to a 32-channel array constructed with the same coil former geometry to precisely isolate the benefit of the 2-fold increase in array coil elements. The constructed coils were developed for a standard clinical 3T MRI scanner and used a contoured head-shaped curved former around the occipital pole and tapered in at the neck to both improve sensitivity and patient comfort. Additionally, the design is a compact, split-former design intended for robust daily use. Signal-to-noise ratio and noise amplification (G-factor) for parallel imaging were quantitatively evaluated in human imaging and compared to a size and shape-matched 32-channel array coil. For unaccelerated imaging, the 64-channel array provided similar signal-to-noise ratio in the brain center to the 32-channel array and 1.3-fold more signal-to-noise ratio in the brain cortex. Reduced noise amplification during highly parallel imaging of the 64-channel array provided the ability to accelerate at approximately one unit higher at a given noise amplification compared to the sized-matched 32-channel array. For example, with a 4-fold acceleration rate, the central brain and cortical signal-to-noise ratio of the 64-channel array was 1.2- and 1.4-fold higher, respectively, compared to the 32-channel array. The characteristics of the coil are demonstrated in accelerated brain imaging.
Prolactin and Psychopathology in Schizophrenia: A Literature Review and Reappraisal

Secretion of the anterior pituitary hormone prolactin can be significantly increased by antipsychotic drugs, leading to a range of adverse effects in patients with schizophrenia. However, there is evidence from a variety of studies that prolactin may also be related to symptom profile and treatment response in these patients, and recent work has identified variations in prolactin secretion even in drug-free patients. In this paper, a selective review of all relevant studies pertaining to prolactin and schizophrenia, including challenge and provocation studies, is presented. The implications of this work are discussed critically. A tentative model, which synthesizes these findings and argues for a significant role for prolactin in the development of schizophrenia, is outlined.
A modified approach to both conventional and ANN based SVPWM controllers for voltage fed inverter in sensorless vector control IM drive

In this paper, space vector pulse width modulation (SVPWM) scheme for voltage fed inverter (VFI) using conventional method and artificial neural network (ANN) based approach are presented separately. In the conventional method, the difficulty of explicitly expressing cross-over and holding-angle as a function of modulation factor in overmodulation mode-I and mode-II respectively are overcome by introducing Newton's Forward Interpolation (NFI). This greatly simplifies the implementation of conventional SVPWM technique without compromising the accuracy issue. The SVPWM is further implemented by ANN based approach built with three subnets to account for three regions of inverter operation distinctly. In comparison to a single ANN taking care of all the three regions, this apparent redundancy of subnets markedly reduces the error in calculating turn-on time for inverter switches. The performances of these two schemes are quantitatively expressed by total harmonic distortion in motor line current. Finally, the schemes are also tested using VFI for sensorless vector control of induction motor drives. The results lead to conclude that the ANN based approach can successfully take over the conventional approach of SVPWM for such applications. The proposed method is validated through computer simulation using MATLAB/SEVIULINK.
Aquisição de mecanização — eletrocentral, cortador de juntas, espuma vibratória, placa de vibração reversa

Aquisição de mecanização (eletrocentral, cortador de juntas, espumas vibratórias, placa de vibração reversa) para ampliar os serviços prestados. O objetivo do projeto é prestar serviços no domínio da preparação de estaleiros de construção. Tendo em conta a necessidade de mecanização na realização do trabalho, a mecanização é uma parte essencial. Os pontos fortes do projeto estão na redução do custo das máquinas alugadas. O risco do projeto é principalmente o desconhecido da empresa no entorno maior, que será tratado pela publicidade. e.
Virtual reality and 3D experiences to IMProve territorial Attractiveness, Cultural heritage smart management and Touristic development.

3D-IMP-ACT will promote cultural heritage among Interreg IPA CBC Italy–Albania–Montenegro countries in order to valorise the existing natural and cultural assets in a systematic, comprehensive and wide way, affecting protection and quality of the environment as basis of any kind of touristic promotion. _x000D_
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It aims at introducing novel approaches regarding the cultural heritage promotion towards smart and sustainable economic development, destination management and marketing, improving the territorial attractiveness, smart management and touristic development of the cultural heritage in Italy (Puglia), Albania and Montenegro, by assessment and enhancement of the inter-regional relations among historical, architectural and archaeological sites._x000D_
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Particularly, the project will focus on the identification of “real” networks connecting sites, buildings and routes, based on historical, environmental and technical characteristics, available territorial infrastructures, as well as on transversal development strategies and polices. Thus, it will address the creation of digital products, 3D VR/AR models and tours, 3D printed artefacts, 3D immersive and creative environments, in order to establish “virtual” networks connecting the above-mentioned places._x000D_
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The final goal is to represent the most relevant sites as “nodes” of a “tangible” framework, featured by trekking paths and cyclist routes, as well as of an “intangible” framework, featured by digital contents that allow immersive and entertaining experiences from one site to the other. The digitalization of different tangible cultural assets including castles, old buildings and the design of new paths for cyclists or pedestrians will help the touristic operators, municipalities, heritage institutions, as well as policy makers at national, regional, or local levels, representatives from research communities, heritage practitioner from the public or private sector._x000D_
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Information added on 2020-05-14, regarding the mitigation of the effects of COVID-19 (the coronavirus pandemic that started in 2019) (English language only): This project, focused on tourism valorisation of cultural and natural heritage also through 3D and digital technologies, made its technological assets available for fight against COVID-19, and through its partner Polytechnic University of Tirana printed 3D protective face shield masks, which were distributed to the Mother Theresa Hospital in Tirana.
Cross border sesar trials for enhanced arrival management

There are periods during the day when variation in aircraft arrival times combine to exceed the capacity of the destination airport to handle them without incurring airborne delay. Such delay causes increased emissions and noise in the vicinity of the airport, as well as increasing the aircraft operator’s fuel costs. Greater congestion increases the air traffic control workload and can result in less efficient aircraft profiles.
To reduce airborne delays near the destination airport and the associated negative effects, two concepts can be used. One is to adjust an aircraft’s departure time by holding it on the ground so that its arrival time avoids the predicted peak in arriving traffic. Other methods involve trajectory extension or slowing down an aircraft in flight. This requires the arrival sequence to be calculated earlier than in current operations so that action can be taken early enough to have a meaningful effect.
The XSTREAM project will demonstrate the benefits gained through this latter concept. These methods can be used in combination with the former concept, traditionally regarded as a network management action, but refined through the use of arrival management tools. The project will demonstrate the use of arrival management techniques for pre-departure aircraft, the calculation, updating and passing of arrival management actions for airborne aircraft such as target time, time-to-lose/gain, or speed advisory from the destination arrival management system to upstream control units, and the impact of multiple arrival constraints within an Upper Airspace Control unit.
The operational demonstrations will be performed upon aircraft arriving at Paris CDG and Orly, London Heathrow and Gatwick, and Zurich. These optimized arrivals will be supported by several en-route Control units, which also will demonstrate how ‘multiple arrival constraints’ can be handled. The project will demonstrate the use of SWIM and remain aligned with engineering standardization work
BMI-Referenced Cut-Points for Recommended Daily Pedometer-Determined Steps in Australian Children and Adolescents

The purpose of this study was to establish sex-specific criterion-referenced standards for pedometer-determined physical activity related to body mass index (BMI)-defined weight status among youth. We analyzed data from 7-16-year-old boys (n = 338) and girls (n = 337) and used pedometer-assessed physical activity and anthropometric data to derive average steps/day and BMI. Sex-specific criterion-referenced standards for steps/day relating to healthy weight and overweight/obese were determined using the contrasting groups method. Healthy weight children took more steps/day than overweight or obese (boys: 14,413 vs. 12,088, and girls: 12,562 vs. 10,114, respectively; p < .001). The optimal BMI-referenced cut-point emerging flom our sample was 16,000 steps/day for both boys and girls. Our results and those reported elsewhere suggest that youth take insufficient pedometer-determined steps/day to avoid becoming overweight.
Thermoluminescent and Monte Carlo dosimetry of IR06-P103d brachytherapy source

This work presents experimental dosimetry results for a new 103Pd brachytherapy seed, in accordance with the AAPM TG-43U1 recommendation that all new low-energy interstitial brachytherapy seeds should undergo one Monte Carlo (MC) and at least one experimental dosimetry characterization. Measurements were performed using TLD-GR200A circular chip dosimeters using standard methods employing thermoluminescent dosimeters in a Perspex phantom. The Monte Carlo N-particle (MCNP) code, version 5 was used to evaluate the dose-rate distributions around this model 103Pd source in water and Perspex phantoms. The consensus value for dose-rate constant of the IR06-103Pd source was found equal to 0.690 cGy·h(-1)·U(-1). The anisotropy function, F(r, θ), and the radial dose function, g(L)(r), of the seed were measured in Perspex phantom and calculated in both Perspex and liquid water phantom. The measured values were also found in good agreement with corresponding MC calculations.
Polarization Presidentialism. How social media reshaped Brazilian politics: a case study on the 2018 elections

Demokratie und Öffentlichkeit im 21. Jahrhundert – zur Macht des Digitalen , Seite 283 - 298