SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Data-Driven genomic computing

Next-generation sequencing technology has dramatically reduced the cost and time of reading the DNA. Huge investments are targeted to sequencing the DNA of large populations, and repositories of well-curated sequence data are being collected. Answers to fundamental biomedical problems are hidden in these data, e.g. how cancer arises, how driving mutations occur, how much cancer is dependent on environment. But genomic computing has not comparatively evolved. Bioinformatics has been driven by specific needs and distracted from a foundational approach; hundreds of methods solve individual problems, but miss the broad perspective.

The objective of GeCo is to rethink genomic computing through the lens of basic data management. We will first design the data model, using few general abstractions that guarantee interoperability between existing data formats. Next, we will design a new-generation query language inspired by classic relational algebra and extended with orthogonal, domain-specific abstractions for genomics. Query processing will trace metadata and computation steps, opening doors to the seamless integration of descriptive statistics and high-level data analysis (e.g., DNA region clustering and extraction of regulatory networks).

Genomic computing is a “big data” problem, therefore we will also achieve computational efficiency by using parallel computing on both clusters and public clouds; the choice of a suitable data model and of computational abstractions will boost performance in a principled way. The resulting technology will be applicable to individual and federated repositories, and will be exploited for providing integrated access to curated data, made available by large consortia, through user-friendly search services.  Our most far-fetching vision is to move towards an Internet of Genomes exploiting data indexing and crawling. The PI’s background in distributed data, data modelling, query processing and search will drive a radical paradigm shift.
Defining optimal morphology of the bond coat–thermal barrier coating interface of air-plasma sprayed thermal barrier coating systems

Abstract The role of bond coat (BC)–thermal barrier coating (TBC) interfacial morphology on the failure of yttria-stabilized zirconia (YSZ) air plasma sprayed (APS) thermal barrier coatings on a NiCoCrAlY bond coat has been investigated. Interfacial morphology plays a key role in the generation of compressive and tensile stresses normal to the global surface plane through oxide growth processes and microstructural evolution, but a functional correlation between BC morphology and coating lifetime for these systems has proved to be elusive. A compilation of quantitative surface morphology parameters – average roughness (S a ), areal root-mean square slope (S dq ), and areal summit density (S ds ) – have been assembled to provide a lifetime-relevant description of interfacial morphology, relative to observed coating failure mechanisms. Current data suggest that a combination of the following BC–TBC morphology parameters have a positive effect on coating system lifetime: (1) an average roughness of 15 μm ± 3 μm, (2) a slope distribution with a summit near 66° ± 3°, and (3) a peak-to-peak summit spacing of approximately 120 μm ± 10 μm. The observed increases in coating lifetime are attributed to the increased effective toughness of the TBC microstructure as a direct result of the morphology of the BC onto which the TBC is sprayed.
FAN ARRAY CONTROL SYSTEM

A fan array fan section in an air-handling system includes a plurality of fan units arranged in a fan array and positioned within an air-handling compartment. One preferred embodiment may include an array controller programmed to operate the plurality of fan units at peak, efficiency by computing the power consumed in various configurations and selecting the configuration requiring minimum power to operate.
MICRO SYSTEMS FOR BIOLOGICAL ANALYSES, THEIR USE FOR DETECTING ANALYTES AND METHOD FOR PRODUCING THEM

The invention concerns a micro system for biological analysis for detecting analytes, for example antigens, in a sample: the micro system comprises a cell (1) provided with a fixed electrode (3) and a mobile electrode (5) along the XX' axis. The electrode(s) are covered with or capable of fixing a specific ligand of the analyte to be detected, for example an antibody. After a sample has been introduced in the cell with electrodes at a removed position, for example at a distance of 2 mu m, the mobile electrode can be brought closer or can be made to oscillate between a removed position (2 mu m) and a close position (0.1 mu m) and a parameter (impedance, viscosity, contact force between the electrodes) representative of the formation of an analyte-ligand layer on the electrode(s) can be measured.
Metal-free CVD coating of graphene on glass and other dielectric substrates

A catalyst-free CVD method for forming graphene. The method involves placing a substrate within a reaction chamber, heating the substrate to a temperature between, and introducing a carbon precursor into the chamber to form a graphene layer on a surface of the substrate. The method does not use plasma or a metal catalyst to form the graphene.
Construction of intensity-duration-frequency (IDF) curves for precipitation with annual maxima data in Rwanda, Central Africa

Abstract. Detailed probabilistic information on the intensity of precipitation in Central Africa is highly needed in order to cope with the risk analysis of natural hazards. In the mountainous areas of Rwanda land slides frequently occur and might cause a heavy toll in human lives. The establishment of Intensity-Duration-Frequency curves for precipitation in Central Africa remains a difficult task as adequate long-term data sets for short aggregation times are usually not available. In 1962 recording raingauges were installed at several stations in Rwanda. According to the climatological procedures in use at that time in Congo, Rwanda and Burundi, maximum monthly and annual precipitation depths for fixed-time durations of 15, 30, 45, 60 and 120 min were determined from the rainfall charts. The data set is completed by the monthly and annual daily precipitation extremes from the non-recording raingauge at the stations. The authors used the dataset to establish the IDF-curves for precipitation at 3 stations in Rwanda having more than 20 yr of operation. The fixed-hour intervals of multiple 15 min require the use of a technique converting data from fixed-time intervals into data of arbitrary starting intervals. Therefore, the van Montfort technique was used.
FEED DEVICE FOR FEEDING ROUND BLANK RINGS MADE FROM PLASTIC AND ARRANGEMENT FOR TRANSPORTING ROUND BLANK RINGS OF THIS TYPE

The invention relates to a feed device (34) for feeding round blank rings (30) made from plastic from a receiving station (35) to a delivery station (36) which is arranged below the receiving station (35) in a vertical direction (H), having a motor-driven conveying unit (58) which is set up to convey a round blank ring (30) downwards in the vertical direction (H) in a positively guided manner such that the orientation of the round blank ring (30) with respect to the vertical direction (H) is predefined at every moment and/or is restricted to a predefined tolerance range.
NovelH∞state estimation of static neural networks with interval time-varying delays via augmented Lyapunov–Krasovskii functional

This paper focuses on studying the H ∞ state estimation of static neural networks with interval time-varying delays via augmented Lyapunov-Krasovskii functional. By constructing a suitable augmented Lyapunov-Krasovskii functional with triple integral terms and linear matrix inequality technique, the delay-dependent criteria are conferred so that the error system is globally asymptotically stable with H ∞ performance. The activation functions are assumed to satisfy sector-like nonlinearities. The desired estimator gain matrix can be characterized in terms of the solution to linear matrix inequalities, which can be easily solved by some standard numerical algorithms. Numerical simulation is given to demonstrate the effectiveness and superiority of the proposed method comparing with some existing results.
Impact and Culture Change After the Implementation of a Preprocedural Checklist in an Interventional Radiology Department

It has been accepted that the implementation of the a preprocedural surgical checklist can reduce perioperative morbidity and mortality in the operating suite. From this success, there has been focus on applying this intervention to other clinical areas. The objective of this study was to evaluate the acceptance and culture change after the implementation of a preprocedural checklist in the interventional radiology suite.A preimplementation audit was performed to identify the need for a checklist in the department. A checklist was then developed, based on the surgical model. At 1 and 12 months after implementation, a survey was distributed to the staff at 3 separate teaching centers.Results showed that opinion of the checklist was generally positive, with staff agreement that it served as an important communication tool was in the patient's best interest, and presented a good opportunity for the team to identify important issues.The checklist was regarded as having little effect on delay between cases. In our setting, the checklist has become a useful and consistent safety measure to ensure that relevant patient data are brought to the forefront before intervention. As a secondary benefit, it also serves as an important communication tool and improves collaboration among team members.
Quick sepsis test

In QUIST, a protein will be validated as a biomarker for early detection and prognosis of sepsis in combination with several other surrogate sepsis biomarkers. Specific objective is:
• To perform a feasibility study in order to gain better insight in the risks and potential hurdles for the validation study in Phase 2 and future exploitation of the project’s results. This study will contain technical, commercial and economical issues.

Expected outcomes: 
• A solid businessplan as a result of the feasibility study. This businessplan will contain information that is currently incomplete or lacking about the market (identification of potential customers, competitors, distributors and competing technologies), regulations and industrial partners for the commercial development of a POCT for sepsis. Based on this information, also a strategy will be defined for IP management.
• A research plan for the validation study, addressing technical hurdles defined in the feasibility study.
Cross-border research network for the integrated design of efficient energy systems in urban regions

According to EUROPE 2020 Strategy and the EU Action Plan for a circular economy, resource-efficiency is strictly linked to the competitiveness and sustainability of territories. It is assumed that high efficiency rates in future building stock, new technologies like low temperature district heating and heat pumps, recovery of heat and energy waste in industry, full exploitation of the potential of biomass, will make our energy systems more clean and efficient. In this context, IDEE project will capitalize the results of Urban Energy Web project (Interreg IVA Italy-Austria) and go beyond it creating a cross-border research network on “integrative system analysis on urban energy systems”. _x000D_
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Such research nucleus will combine the complementary competences of 4 partner research centres and one public authority to develop an integrated bottom-up assessment framework on urban energy systems. A new integrative model framework will be elaborated, interpreting energy, environmental, building, economic and geographic information data will be jointly elaborated to support local authorities and other key stakeholder to plan energy investments in urban areas, giving strategic inputs on available potentials, the most innovative applicable technological solutions and their environmental impact, costs and return on investment. Such models will be applied in pilot selected areas (Maniago - FVG, Feltre - Veneto and Salzburger Seenland - Austria), thus being replicable also in other territories.
Evaluation of a non-invasive vocal cord vibration switch as an alternative access pathway for an individual with hypotonic cerebral palsy – a case study

A novel non-invasive vocal cord vibration switch for computer access was designed for an individual with hypotonic cerebral palsy. An evaluative case study was performed to compare the new device to an existing commercially available voice-activated switch in terms of sensitivity, specificity, speed, and user fatigue.The participant wrote pangram sentences with the two switches over 4 days with two sessions each day (morning and afternoon). The order of the switches was alternated and a new sentence was used each day. The user's perceived level of exertion was noted before and after each task and activation errors were logged for performance analysis. After using the device for 2 months, a qualitative survey was administered with the participant and his educational assistant.The vocal cord vibration switch outperformed the voice-activated switch in terms of sensitivity (p < 10(-4), t-test), speed (p < 10(-3)), and user-perceived exertion (p < 10(-4)). Qualitatively, both the participant and his educational assistant were more satisfied with the proposed switch relative to his existing solution.The results of this study show that the vocal cord vibration switch provides a promising new alternative for individuals with severe and multiple disabilities who are able to hum or produce vocalizations.
Post-Snowden circuits and design methods for security

Summary: Comprehensive set of circuits and design methods to create next generation electronic circuits with strong built-in trust and security. 
       Electronics are integrating/invading into the human environment at an amazing speed, called the Internet-of-Things and next the Internet-of-Everything.  This creates huge security problems. Distributed (e.g. body) sensors, pick up often very private data, which is sent digitally into the cloud, over wireless and wired links. Protection of this data relies on high-quality cryptographic algorithms and protocols. The nodes need to be cheap and lightweight, making them very vulnerable to eavesdropping and abuse. Moreover, post-Snowden, society realizes that the attack capabilities of intelligence agencies, and probably following soon of organized crime and other hackers, are orders of magnitude stronger than imagined. Thus there is a strong demand to re-establish trust in ICT systems. 
       In this proposal we focus on the root of trust: the digital hardware. The overall objective is to provide fundamental enabling technologies for secure trustworthy digital circuits which can be applied in a wide range of applications. To master complexity, digital hardware design is traditionally split into different abstraction layers. We revisit these abstraction layers from a security viewpoint: we look at process variations to the benefit of security, standard cell compatible digital design flow with security as design objective, hardware IP blocks for next generation cryptographic algorithms and protocols (e.g. authenticated encryption schemes, post-quantum public key schemes), integration into embedded HW/SW platforms, and methods to provide trust evidence to higher levels of abstraction. To strengthen the security we investigate the links between the layers. Finally an embedded application is selected as design driver, the security evaluation of which will be fed back to the individual layers.
FÜHRUNG IM FOKUS

Die Umsetzung des FOCUS LIGHT-Projekts wird direkt zur Steigerung der Wettbewerbsfähigkeit führen und das Exportpotenzial von Skale FOCUS AD durch die Einführung und Implementierung von IKT-basierten Software-Management- und Ressourcenmanagementsystemen, Produkt-/Dienstentwicklungsprozessen und Kerngeschäftsprozessen sowie die Einführung eines Umweltmanagementsystems nach ISO 14001 freisetzen.Der erwartete Beitrag des Projekts steht in direktem Zusammenhang mit der Verbesserung der Marktpräsenz des Unternehmens, der Steigerung der Produktivität, der Optimierung der Kosten und der Steigerung des Mehrwerts auf allen Ebenen der Organisation.In diesem Zusammenhang sieht das Projekt die Umsetzung der folgenden Kernaktivitäten vor:1) Das Projekt steht in direktem Zusammenhang mit der Verbesserung der Marktpräsenz der Unternehmenspräsenz, der Optimierung der Kosten und der Steigerung des Mehrwerts auf allen Ebenen der Organisation.In diesem Zusammenhang sieht das Projekt die Umsetzung der folgenden Kernaktivitäten vor:1) Das Projekt steht in direktem Zusammenhang mit der Verbesserung der Marktpräsenz der Unternehmenspräsenz, der Optimierung der Kosten und der Steigerung des Mehrwerts auf allen Ebenen der Organisation. In diesem Zusammenhang sieht das Projekt die Umsetzung der folgenden Kernaktivitäten vor:1) Das Projekt steht in direktem Zusammenhang mit der Verbesserung der Marktpräsenz der Unternehmenspräsenz, der Optimierung der Kosten und der Steigerung des Mehrwerts auf allen Ebenen der Organisation.In diesem Zusammenhang sieht das Projekt die Umsetzung der folgenden Kernaktivitäten vor:1) Das Projekt steht in direktem Zusammenhang mit der Verbesserung der Marktpräsenz des Unternehmens in der Unternehmenspräsenz, der Optimierung der Kosten und der Steigerung des Mehrwerts auf allen Ebenen der Organisation.In diesem Zusammenhang sieht das Projekt die Umsetzung der folgenden Kernaktivitäten vor:1) Das Projekt steht in direktem Zusammenhang mit der Verbesserung der Marktpräsenz des Unternehmens in der Unternehmenspräsenz, der Optimierung der Kosten und der Steigerung des Mehrwerts auf allen Ebenen der Organisation. In diesem Zusammenhang sieht das Projekt die Umsetzung der folgenden Kernaktivitäten vor:1) Das Projekt ist in direktem Zusammenhang mit der Verbesserung der Marktpräsenz des Unternehmens in der Unternehmenspräsenz, der Optimierung der Kosten und der Steigerung des Mehrwerts der Organisation.In diesem Zusammenhang sieht das Projekt die Umsetzung der folgenden Kernaktivitäten vor:1) Das Projekt ist in direktem Zusammenhang mit der Verbesserung der Marktpräsenz des Unternehmens in der Unternehmenspräsenz, der Optimierung der Kosten und der Steigerung des Mehrwerts auf allen Ebenen der Organisation. In diesem Zusammenhang sieht das Projekt die Umsetzung der folgenden Kernaktivitäten vor:1) Das Projekt steht in direktem Zusammenhang mit der Verbesserung der
Voltage control of chiral spin structures

This project will develop a new way to manipulate chiral spin structures such as skyrmions using voltages. Building on the expertise of the fellow in voltage control of magnetism in multiferroic heterostructures, this project uses the unique Spin-Polarised Low Energy Electron Microscope (SPLEEM, in Berkeley) to characterize chiral spin structures in tailored multiferroic heterostructures. By studying (in Leeds) the effects of voltage control on current-driven skyrmion motion in these heterostructures, V-ChiralSpin aims to establish a new, technologically relevant, research area.
Representing digital data with magnetic skyrmions offers a promising route to reduce the vast energy consumption and carbon footprint associated with current information technologies. Skyrmion sizes can be in the nanometre range and controlling them with voltage will reduce or eliminate the need for power-hungry electric currents or magnetic fields. 
The approach will be to manipulate chiral spin textures in tailored epitaxial multilayers via interfacial strain transfer from ferroelectric and piezoelectric substrates. The mechanisms coupling micromagnetic phenomena to voltage signals will be determined through SPLEEM imaging, micromagnetic simulation, and current-driven transport measurements as a function of voltage-controlled strain. Beyond transport properties, we will explore the use of voltage signals to write and delete skyrmions and other spin textures. 
The fellow will become an expert in the technique of SPLEEM, in the field of chiral spin structures, and in magneto-transport measurements. This fellowship will build and strengthen networks of researchers that will benefit both the fellow and the team members in the hosts. Leeds will benefit from knowledge transfer through the fellow of expertise in SPLEEM and chiral spin structures. Both Berkeley and Leeds will profit from the Fellow’s knowledge of electric field control of magnetism and expertise in micromagnetic simulations.
PROYECTO COMISAR_UNICA_BANDO CLÚSTER DE ARRIBA HACIA ABAJO

EL PROYECTO COMISAR SE REFIERE AL DESARROLLO DE TECNOLOGÍAS INNOVADORAS BASADAS EN EL USO DE MICROALGAS PARA LA PRODUCCIÓN DE PRODUCTOS DE ALTO VALOR AÑADIDO, Y LA RECOGIDA SIMULTÁNEA DE CO2 EN UN CONTEXTO DE BIORREFINERÍA AGROINDUSTRIAL. ENTRE LOS PRODUCTOS EXTRAÍBLES DE MICROALGAS SE PUEDEN INCLUIR, POR EJEMPLO, OMEGA-3, VITAMINAS, ANTIOXIDANTES, ALIMENTOS FUNCIONALES Y PRECURSORES DE DIFERENTE NATURALEZA QUE SE COMERCIALIZARÁN EN DIFERENTES MERCADOS ESTRATÉGICOS COMO NUTRACÉUTICO, BIOMÉDICO, COSMÉTICO Y AGROALIMENTARIO. EL USO DE LAS TECNOLOGÍAS INVESTIGADAS TAMBIÉN TENDRÍA IMPORTANTES REPERCUSIONES EN EL SECTOR MEDIOAMBIENTAL ASOCIADO A LA REUTILIZACIÓN DEL CO2 DE LOS GASES DE ESCAPE Y A LA DEPURACIÓN DE LOS RESIDUOS URBANOS. EL SUBPRODUCTO DEL PROCESO PODRÍA UTILIZARSE PARA LA PRODUCCIÓN DE FERTILIZANTES O COMO FORRAJE. LA APLICACIÓN ADICIONAL DEL PROCESO ES LA EXTRACCIÓN DE MICROALGAS DE PRECURSORES QUE SE PUEDEN UTILIZAR EN EL CRECIENTE MERCADO DE BIOPLÁSTICOS
Service Condition of Railroad Corridors around the Insulated Rail Joints

AbstractRailroad corridors contain a large number of insulated rail joints (IRJs) that act as elements (critical to safety) in the circuitries of signaling and broken rail identification systems. IRJs are regarded as sources of excitation for the passage of loaded wheels that lead to high-impact forces. These forces in turn cause dips, cross levels, and twists to the railroad geometry in close proximity to the sections that contain IRJs, in addition to local damage to the railhead of the IRJs. Therefore, a systematic monitoring of IRJs in railroads is prudent to mitigate the potential risk of their sudden failure (e.g., broken tie plates) as a consequence of rail traffic. This paper presents a simple method of periodic recording of images using time-lapse photography and total station surveying measurements to understand the ongoing deterioration of IRJs and their surroundings. Over a 500-day period, data were collected to examine the trends in narrowing of the joint gap that is attributable to plastic de...
ENERGY EXTRACTION APPARATUS AND METHOD

An apparatus and method for extracting energy from fluid motion comprising a deformable body adapted to be deformed by fluid motion, wherein the deformation of the deformable body is arranged to drive at least one energy medium to be delivered to an energy output; and wherein the energy medium is controllable in order to control at least one dynamic response of the deformable body.
LEPABE-2-ECO-INNOVAZIONE

LEPABE-2-ECO-INNOVATION includes:RL1: Processi e prodotti sostenibili — 1.1. Energia da fonti rinnovabili 1.2. Efficienza energetica 1.3. Compositi innovativi e 1.4. Prodotti e processi basati sulla nanotecnologia RL2: Risorse sostenibili e valorizzazione — 2.1. Biofilm 2.2. Applicazioni biotecnologiche marine 2.3. Soluzioni integrate per i rischi emergenti nella WWTP e 2.4. Soluzioni integrate per il trattamento e il recupero dei rifiuti.