SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Avaliação dos níveis séricos de BDNF em pacientes pediátricos com neoplasia

BACKGROUND: The childhood cancer represents about 0.5 to 3% of all cancers of the general population. From a clinical standpoint, infant tumors grow quickly and are more invasive than the adult cancers, but respond better to treatment and are considered a better prognosis. The neurotrophins and their receptors (tropomyosin-related kinase Trk) are important regulators of survival, development and neuronal plasticity. They are also involved in the oncogenic process, which can facilitate or suppress tumor growth. BDNF (Brain-derived neurotrophic factor) is a neurotrophin that has a specific binding with the receptor TrkB, and is also involved in different bodily processes. This study aimed to evaluate the serum levels of BDNF in pediatric patients (children and adolescents) with some type of cancer and healthy individuals, as well its relationship with gender, age, platelet value and survival. PATIENTS AND METHODS: Cross-sectional study with children and adolescents aged zero to 18 years. The study included 114 patients, 72 patients in the group of children with cancer and 42 control group. Analysis of the serum levels of BDNF was performed by ELISA. The project was approved by the Ethics Committee of HCPA. RESULTS: The median (P 25-75) values of BDNF were 2,45 (0,76-5,23) pg/ml for the group with ALL, 0,45 (0,08-0,80) pg/ml for the group with LMA, 9,0 (3,14-14,7) pg/ml for the group with lymphomas and solid tumors and 6,08 (2,60-9,35) pg/ml in the control group. There was no difference between the values of BDNF compared the gender and age among the different groups. Regarding the values of BDNF and platelets, there were significant differences between groups of patients diagnosed with leukemias and other groups. Patients with cancer who had BDNF values lower than 4,00 pg/ml had a lower survival curve (p<0,05).
BEACHMED-e - La gestion stratégique de la défense des littoraux pour un développement soutenable des zones côtières de la Meditérannée

Coastal strips, especially those between the sea and land, are morphologically sensitive and depend on a delicate equilibrium between marine processes and sediment deposits. The partner regions are all exposed to a greater or lesser extent to coastal erosion. This erosion has worrying effects on the environment, which are aggravated by the rising sea level, deepening of the sea bottom, more frequent storms and coastal flooding and erosion. Overall objective / Objectif général Based on the experience of the Beachmed project financed by IIIB MEDOCC, Beachmed-e focuses on strategic management of coastlines with the aim of achieving sustainable development of coastal areas facing a constant threat of erosion. The common coastal management strategy proposed by the operation aims to identify instruments to evaluate the condition of the coast, to restore the coastal strip and to apply planning as well as to draw up a regulatory framework on coastal management. Also a study will be carried out on the creation of a European Observatory for the defence of the Mediterranean coasts. Expected results / Résultats attendus The results expected are the identification of measures to mitigate coastal erosion, acceptance of recommendations for land planning in the regions, improved management of coastal domains and the provision of innovative territorial technologies. Master plans and technical reports will also be drawn up for subsequent implementation. Moreover, the project aims to draw up guidelines and recommendations so that the results of the RFO can be included in policies and regulations in the participating regions.
Analysing Debris-Flow Impact Models, Based on a Small Scale Modelling Approach

The objective of this study is to analyse adaptable debris-flow impact models, which are very important for mitigation measurements and buildings using their sphere of influence. For this reason, 16 debris-flow experiments, on a small-scale modelling approach, were performed. Impact forces were measured with a force plate panel, consisting of 24 aluminium devices, coaxially mounted with resistance strain gauges. Flow velocities, flow heights as well as horizontal impact forces were sampled with a frequency of 2.4 kHz. Sub datasets of sampled raw force data were defined by applying an average median filter, a low-pass filter routine. Further, estimated peak pressure values as well as empirical coefficients of hydraulic impact models were compared, and the influence of signal processing is discussed.
Transferring hydrological and biogeochemical concepts from boreal to mediterranean riparian zones: developing a broad knowledge framework across ecoregions

Science-based, sustainable management is needed to preserve the diverse and essential services provided by freshwaters. In natural and semi-natural areas, up to 90% of the total river length is in headwaters (i.e. small streams). Water quality in these “lungs of the landscape” is controlled primarily by soils adjacent to streams, i.e. riparian zones (RZs). Within RZs, the dominant source layer (DSL), a localized hotspot, contributes most of the solute and water fluxes to streams. However, the relative importance of DSL hydrological and biogeochemical processes controlling freshwater quality varies across ecoregions. The overall aim of RIPARIONS is to develop a unified knowledge framework based on DSL hydrological and biogeochemical functions across Europe to predict material transfer from soils to surface waters and consequent effects on water quality. Specifically, RIPARIONS will extend the DSL conceptual model developed in the boreal ecoregion by testing its applicability in two contrasting (sub-humid and a semi-arid) Mediterranean catchments. First, DSLs will be identified via hydrological site characterization using digital elevation models and on-site measurements. Biogeochemical investigations will link DSL processes and stream solute processing to assess stream water quality. Modelling of climate change impacts on DSL position and subsequent effects on future water quality will be assessed. Finally, a synthesis and integration of this work with previous and ongoing work in boreal and temperate sites will create a unified framework predicting RZ function and water quality across European ecoregions based on the DSL concept. While the Water Framework Directive mandates protection of RZs to maintain ecological status of rivers, it does not state how to manage them. RIPARIONS will fill this gap by identifying hotspots of water movement/processing within RZs (i.e. DSLs) that are the most influential for freshwater chemistry, and thus the most in need of protection
Power analysis and optimization of the ZUC stream cipher for LTE-Advanced mobile terminals

In this paper we devise and compare several hardware implementations of the confidentiality algorithm that is based on the ZUC stream cipher. First we design and analyze a reference architecture, which reflects a basic implementation of the algorithm, with respect to power and area consumption in order to identify design's bottlenecks. Then different architectures for the most power demanding operations are explored to reduce the power consumption at the register transfer level. These architectures are evaluated at various timing constraints to account for data rates from LTE up to LTE-Advanced. The hardware analysis is done using Faraday's 90 nm standard cell library. Our results show that 19% of power savings with 2% of area reduction can be achieved by using a cryptographic substitution box with one-hot encoding. When combining this with parallel LFSR architectures, power savings can be raised up to 37%, but with an area overhead of 10%.
Développement d’un concept de services de santé utilisant la technologie mobile

L’objectif du projet de développement est de lancer un nouveau concept de services de santé utilisant la technologie mobile pour relever le plus grand défi auquel le secteur de la santé est confronté: Comment influez-vous sur le comportement de santé du patient/client et sur les choix faits en dehors du temps d’accueil? Au cours du projet, un concept de service utilisant la technologie mobile sera développé à l’intention des professionnels de la santé et de leurs clients. L’objectif est de construire une manière de travailler vers une interaction plus étroite entre le professionnel de la santé et le client, permettant ainsi d’assurer des services de santé plus efficaces, tout en cherchant à surmonter la situation où le patient se sent seul dans ses soins. Dans le même temps, les professionnels de la santé reçoivent des clés pour influencer le comportement des clients en matière de santé.
Designing for Success: Developing Engineers Who Consider Universal Design Principles.

Engineers must design for a diverse group of potential users of their products; however, engineering curricula rarely include an emphasis on universal design principles. This research article details the effectiveness of a design project implemented in a first-year engineering course in an effort to raise awareness of the need for engineers to be more inclusive when designing. Students were asked to apply universal design principles to redesign an engineering laboratory to make it more usable to all, including individuals with disabilities who use the room. A representative from the university’s disability services staff, as well as individuals with first-hand experience of disability, provided guidance to the class by serving as project mentors. Design decision analyses were reviewed to determine the specific criteria student teams believed were most important in identifying specific design ideas to pursue. These analyses were used to evaluate the success of this project in helping students be more cognizant of the need for designs to be flexible, versatile, and universally designed. These criteria were compared to projects from previous classes in which universal design had not been explicitly addressed. Results indicated that students who participated in the universal design project were much more likely to consider criteria related to universal design principles, though they identified accessibility as more important than the more overarching goals of achieving a universally usable design. Results suggest that such a universal design project is one possible model to better prepare engineering students and that the model can be strengthened through involvement of disability services professionals.
Quotanda - a lending-as-a-service (laas) platform that enables schools and lenders  to set up student financing programs to make education more affordable

Quotanda is a lending as a service (LaaS) platform providing a suite of student loan services. Its technology and staff supervise all aspects of partners’ online lending programs, including: program set-up, marketing, compliance to selection requirements, origination, automated credit decisions, loan disbursement, extended servicing (collecting interest and principal), and default management. As a B2B2C LaaS platform, two are the main groups Quotanda is addressing to: banks and schools through which students, which are the final users, are eventually pointed. Quotanda manages all aspects of loan programs for banks or extended payment plans for schools. It supports economic growth via wage premiums for educated (or re-skilled workers) and helps to reduce deficiencies of inequality and social exclusion. Quotanda is challenging the status-quo with a technology that broadens financial inclusion and access to education by helping schools to introduce flexible and affordable financing programs for students, as shown by the 2 successful loan programs running in Spain in collaboration with IESE Business School MBA and IronHack – Spain’s first code bootcamp. On the other side it helps banks to acquire millennial customers with high Lifetime Value efficiently while making students and families loan decision faster. Having proved online origination and servicing capabilities, Quotanda sees this feasibility study as an opportunity to help grow and test its turnkey platform on a larger level, by bringing superior efficiency at scale to various banks and schools. Its concept greatest ambition is to set a standard the education lending market with an increasing share that will arrive to count at least for 1.75% of the entire online education lending market in the forthcoming 4 years, by closing partnerships with 11 lenders and 40 among universities, schools and code bootcamps by the end of 2017.
Method for making a wall of glass building blocks, tiles or like building elements

360,625. Walls ; glass building blocks and tiles. NAAMLOOZE VENNOOTSCHAP GLASFABRIEK LEERDAM VOORHEEN JEEKEL, MIJNSSEN, & CO., Leerdam, Holland. Oct. 17, 1930, No. 31209. Convention date, Oct. 17, 1929. [Classes 20 (iv) and 87 (i).] A wall is made of box-shaped glass blocks and tiles spaced apart by elastic spacing pieces 3 which cover a part only of the horizontal bearing surfaces of the blocks and may be fastened to the blocks or inserted between them while building the wall. The joints are filled in with mortar 12. Blocks as shown in Fig. 1 are hollow underneath and may be assembled to break joint.
Evac +International

Does the project?EVAC +International? aim to strengthen the competitive and differentiated position of EVAC? Ventilation and Air Conditioning Equipment, S.A. in international markets.
Bootstrapping inflationary cosmology

Cosmic inflation is one of the most promising explanations for the origin of the structure in the observed universe. However, while quantum-mechanical fluctuations during an early epoch of inflationary expansion provides a remarkably good description of the data, establishing the precise field content during inflation is a fundamental challenge for primordial cosmology. Since it is almost certain that the inflationary era involved physics beyond the Standard Model, this is also an incredible opportunity to learn about physics at the highest energy scales from current and future cosmological observations.

On the theoretical side, it is important to classify the signatures of new degrees of freedom in primordial correlation functions to compare with observations. However, progress has been hindered due to the lack of tools to go beyond the simplest of cases. I propose a research and training programme to develop new systematic tools at the interface between scattering methods in de Sitter (dS) space, and, via holography, the conformal bootstrap in the dual CFT picture, to carve out the non-Gaussianities associated to: (1) Regge trajectories of higher-spin fields predicted by string theory/other UV complete theories of gravity (2) partially massless higher-spin fields, both at tree and 1-loop level. 

This proposal combines my expertise on higher-spin theories, scattering methods on anti-dS and holography with extensive training on various aspects of inflation and CMB physics from world-leading experts at IAS Princeton. The project will be completed at ULB, whose complementary expertise on higher-spins and holography will provide fertile ground to transfer my knowledge gained from the outgoing phase and continue the directions generated by the project. The importance of the project outcomes to cosmology and high-energy physics, as well as the experience gained, will facilitate me in obtaining a junior researcher position in Europe – the natural next step in my career.
Cross-border startup accelerator +

The MARITTIMOTECH + project aims to promote the competitiveness of new businesses in the cross-border priority sectors defined by the Programme. The project will promote entrepreneurship by encouraging the creation of new businesses, especially by facilitating the economic exploitation of new entrepreneurial ideas related to blue and green growth. A cross-border system will allow aspiring entrepreneurs and young start-ups to access cross-border services. To this end, a cross-border call for applications will be made, with the beneficiaries being selected based on criteria defined using a joint cross-border methodology. This will define how the cross-border assistance services will be provided that will mobilise accessible scouting, mentoring, coaching and training methodologies, following a series of cross-border sessions and stages, especially using dematerialised tools. This acceleration path will include a comprehensive analysis of the business idea, a cross-border networking event, five group courses, five workshops and individual support. A final cross-border competition will take place to select several companies that will be able to participate for free in an event of international importance. The MARITTIMOTECH + project will be the logical continuation of various projects that have already been launched as part of previous calls, capitalising on them at different levels. This ‘capitalisation’ will initially be achieved by reusing and adapting the tools that have already been developed, mainly the MARITTIMOTECH, Frinet2 and SUCCESS platforms, but also all the documentation and studies carried out. In a second phase, capitalisation will be based on the experience developed by the partnership in offering services to new businesses.
Automated Modelica Package Generation of Parameterized Multibody Systems in CATIA

In early stages of the product development process computer-aided design (CAD) and multibody simulation (MBS) work concurrently to build a virtual mechanical system. While CAD handles the geometric design and space analysis, MBS leads to a deeper understanding of the dynamic behavior of the future system. The CAD system has to provide physical and geometrical data, such as mass, inertia and connecting frames in order to improve simulation results. Automation at this point helps to create consistent simulation and design models and shortens the amount of time needed to produce realistic simulation results. Based on Visual Basic for Applications (VBA) a method is implemented to automatically generate an isolated Modelica model package or a single Modelica model from CATIA assemblies or parts. The introduction of design controlling parameter variables in addition to the multibody data enables optimization loops between multibody simulation and the related CAD model. An example demonstrates the three main steps of the presented method, divided into model processing, package generation and parameterized package update. Furthermore, the update process is integrated in a manual parameter variation as well as an automated optimization routine to enable parametric design studies coupled with multibody simulation.
Long-term study of dune infiltration systems to treat coastal stormwater runoff for fecal bacteria

Abstract The discharge of untreated stormwater runoff into recreational waters places swimmers at risk of contracting various illnesses and often results in beach closures or swimming advisories. In an effort to safeguard the public, two experimental Dune Infiltration Systems were installed beneath the sand dunes in Kure Beach, NC. The systems diverted stormwater from two existing beach outfalls, which drained 1.9 ha (4.7 ac) and 3.2 ha (8.0 ac) watersheds, into subsurface chambers for temporary storage and infiltration into the existing sand dunes. A 3-year study examined the long-term performance of the two systems during which 14,584 m 3 (515,046 ft 3 ) of stormwater was diverted into the dunes, with only 438 m 3 (15,457 ft 3 ) bypassing the systems, a nearly 97% capture rating. Enterococci concentrations in stormwater runoff from the watersheds exceeded the state's single sample maximum for Tier I waters (104 MPN/100 mL) in >70% of samples, with geometric means ≥278 MPN/100 mL. Groundwater enterococci concentrations tended to remain below the state limit (≤11% exceedance), with geometric means ≤7 MPN/100 mL. Groundwater monitoring in the control dune, with no direct input of stormwater, had a geometric mean of 5 MPN/100 mL and a 6% exceedance rate. The influences on the local water tables were temporary, as the water table would mound around the systems during infiltration events and dissipate to within pre-storm variations from the control within hours or up to approximately 2 weeks. The Dune Infiltration System appears appropriate for installation in small watersheds (
Determination of environmental radioactivity (238U, 232Th and 40K) and indoor natural background radiation level in Chennai city (Tamilnadu State), India

An extensive study on the determination of the natural radioactivity ((238)U, (232)Th and (40)K) levels in soil samples of Chennai city, India has been undertaken and the results of the same are compared with the levels reported in other Indian cities as well as other parts of the world. The radioactivity content in the soil samples, the absorbed dose rate, annual effective dose equivalent, radium equivalent activity, internal and external hazard indices were calculated and compared with UNSCEAR 2000 recommended values. In addition to the above, mapping of indoor natural background gamma radiation levels has been made using thermo luminescent dosemeters throughout Chennai city and the same are reported.
Asilo y refugio. El legado colonial en el humanitarismo actual

Asilo y refugio. El legado colonial en el humanitarismo actualEn este artículo se analiza la huella colonial presente en la gestión humanitaria actual, atendiendo al caso concreto de asilo y refugio en Europa, trazando un devenir histórico a partir de las consideraciones plasmadas por Bartolomé de las Casas en su obra Brevísima relación de la destrucción de las Indias.Partiendo de esta obra, se analizan distintos periodos de la gestión internacional del humanitarismo, para destacar aquellos aspectos que se van modificando en su forma de actuar pero que continúan estando marcados por la visión colonial y la perpetúan.Se repara
Optimal block designs for diallel crosses

Dey and Midha (Biometrika 83(2):484–489, 1996) constructed optimal block designs for complete diallel cross experiment using triangular partially balanced incomplete block designs with two associate classes. They listed optimal block designs for the lines in the range from 5 ≤ v ≤ 10. In this paper, we are also proposing additional optimal block designs for complete diallel cross experiment using two associate class partially balanced block designs for some additional values of v. Our method yields designs for proper and non-proper settings for complete diallel cross experiments. The proper and non proper designs are optimal in the sense of Kempthorne (Genetics 41:451–459, 1956) and non-proper designs are universally optimal in the sense of Kiefer (A survey of statistical design and linear models, North Holland, Amsterdam, 1975). The list of practically important designs is also given.
Energy Efficient Communication with Interdependent Source-Channel Coding: An Enhanced Methodology

The primary design goals of an energy constrained Wireless Sensor Network are bit error rate (BER) performance and energy efficiency. An enhanced methodology is proposed in this paper for the energy efficient Interdependent Source-Channel Coding scheme. The scheme minimizes the energy overhead for encoding/decoding and redundant bits' transmission typical of a forward error correction scheme. An intensified BER performance and a significant amount of compression in place of redundancy compared to standard codes are achieved. The proposed methodology, validated in the context of Mica2 mote and MicaZ mote, yields a notable raise in compression and coding gain compared to the earlier proposed methodology.