SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
DRY ETCH PROCESS

A method for conformal dry etch of a liner material in a high aspect ratio trench is achieved by depositing or forming an inhomogeneous passivation layer which is thicker near the opening of a trench but thinner deep within the trench. The methods described herein use a selective etch following formation of the inhomogeneous passivation layer. The selective etch etches liner material faster than the passivation material. The inhomogeneous passivation layer suppresses the etch rate of the selective etch near the top of the trench (where it would otherwise be fastest) and gives the etch a head start deeper in the trench (where it would otherwise be slowest). This method may also find utility in removing bulk material uniformly from within a trench.
Information technology and institutions supporting human capital accumulation and exchange

Information technology revolutions transform the production and exchange of ideas and drive profound institutional and cultural change. History provides unique settings to document the causal impact of changes in information technology and institutions, and the best evidence on their long-run effects.
The objective of the research is to document the impact of revolutionary transformations in information technology and institutions using evidence from the European Renaissance. Printing was the new information technology of the Renaissance and is arguably the best parallel to the internet. Print media transmitted ideas that led to significant institutional change. But no quantitative research systematically documents the impact of these innovations.
The research will innovate by constructing ground-breaking micro-data on media markets, human capital, and institutions; developing cutting edge estimators for high-dimensional data to measure ideas in the media; and using historical sources of exogenous variation to identify cause and effect.
The research has three strands. The first will document the impact of competition on idea diffusion and institutional change during the Protestant Reformation. The research will construct firm-level data on all known books in German-speaking Europe 1450-1600, use high-dimensional estimators to measure ideas in print, and identify exogenous variation in competition from archival data.
The second strand will document the origins of persistent differences in human capital accumulation by constructing new data on city laws that set up the first experiments in public education and on virtually all German university students 1400-1550, and by using local shocks to support causal inference.
The third strand will document the impact of organizations supporting knowledge diffusion that were complementary to printing by constructing data on all European scholarly societies and journals and using historical shocks to identify their impact.
Verbesserung der Produktionskapazität von Milkotronic Ltd.

Projekt "Verbesserung der Produktionskapazität von Milkotronic Ltd. zielt darauf ab, eine Spritzgießmaschine und ein universelles Bearbeitungszentrum zu kaufen. Unser Unternehmen produziert Milchanalysatoren als eine der größten Herausforderungen für unser Unternehmen ist es, seine Produktionskapazität zu verbessern. Die Realisierung unseres Projekts wird zur Steigerung der Wettbewerbsfähigkeit und zur Stärkung des Exportpotenzials unserer Fabrik beitragen, indem die Produktionskosten gesenkt und Ressourcen optimiert werden.
Innovation of the preparation of the moulding mixture and the properties of castings

This project concerns an application of completed development, where we have successfully cooperated with the Technical University of Liberec (TUL) and whose main aim is to increase the quality-technical properties of the moulding mixture itself through the introduction of the preparation of the moulding mixture (modern solution for the preparation of a single bentonite mixture) and thus to increase the qualitative properties of the castings (surface, geometric and shape accuracy of castings, porosity). Customs code of production: 7616 99 10 99. a.
Development of smart and flexible freight wagons and facilities for improved transport of granular multimaterials. (hermes)

Rail freight transportation is a system service where a multitude of players, participants and systems providers bear a high degree of responsibility for its attractiveness and performance. It shows high efficiency as transportation means, in terms of land use and energy consumption and low greenhouse gas emissions. However rail’s market share of freight transportation and its economic efficiency continues to be limited. Aimed at overcoming such uncertainty, this project addresses one of the most important key resources for further developing rail freight transportation: the optimization of the performance of the rail freight wagon. The continuous pressure on environmental issues and energy efficient transport is forcing the rail transportation sector to enhance the rail logistics services and to incorporate innovative solutions to improve load capacity to keep the “best-in-class” position and, therefore, acquiring a much privileged position beyond alternative terrestrial transport source, as truck transportation. Thus, aimed at optimizing rail freight transportation, the main objective of this project is to holistically address the aspects that may improve freight wagon performance: enhanced logistics, improved multimodal operative, higher load capacity, optimized filling/emptying time and flexibility to transport multi-products. 

This project aims to achieve such optimization by combining industrial expertise on the freight wagon design and construction, advanced materials for lightweight construction and logistics with the research capabilities to incorporate innovation solutions and optimize material performance.
Clostridium difficile colitis in an immunocompromised patient treated with fidaxomicin

The incidence of C. difficile-associated colitis has significantly increased in recent years in hospitals and long-term healthcare facilities. It has a great impact on morbidity and mortality, particularly in high-risk patients (e.g. elderly and subjects with comorbidities or immunosuppression), who frequently have severe or recurrent infections and sometimes do not respond to conventional therapy with metronidazole or vancomycin. Fidaxomicin, recently approved in clinical use, is a new option for the treatment of C. difficile infections.A 65-year-old woman with cryptogenetic decompensated cirrhosis underwent orthotopic liver transplantation and started immunosuppressive therapy. She had a prolonged hospitalization of nine months after transplantation with several infectious complications and numerous episodes of severe C. difficile-associated colitis. Metronidazole and vancomycin were not completely effective. Fidaxomicin showed a sustained clinical cure without other recurrence.
Enhancing Digital Simulated Laboratory Assessments: a Test of Pre-Laboratory Activities with the Learning Error and Formative Feedback Model

Digitally simulated laboratory assessments (DSLAs) may be used to measure competencies such as problem solving and scientific inquiry because they provide an environment that allows the process of learning to be captured. These assessments provide many benefits that are superior to traditional hands-on laboratory tasks; as such, it is important to investigate different ways to maximize the potential of DSLAs in increasing student learning. This study investigated two enhancements—a pre-laboratory activity (PLA) and a learning error intervention (LEI)—that are hypothesized to enhance the use of DSLAs as an educational tool. The results indicate students who were administered the PLA reported statistically lower levels of test anxiety when compared to their peers who did not receive the activity. Furthermore, students who received the LEI scored statistically higher scores on the more difficult problems administered during and after the DSLA. These findings provide preliminary evidence that both a PLA and LEI may be beneficial in improving students’ performance on a DSLA. Understanding the benefits of these enhancements may help educators better utilize DSLAs in the classroom to improve student science achievement.
Severe Monkeypox in Hospitalized Patients — United States, August 10–October 10, 2022

¶ A list of severe manifestations of monkeypox can be found at https://emergency
REGELUNG FÜR EIN SIMULIERTES BOHRLOCH ZUM PRÜFEN MIT DYNAMISCHEM UNTERDRUCK

Um die Effizienz eines Perforierungswerkzeugsystems zu optimieren, können untertage herrschende Bedingungen simuliert werden, um die optimale Auslegung für das Perforierungswerkzeugsystem zu bestimmen. Ein simuliertes Bohrloch ist in einer simulierten Bohrlochummantelung angeordnet und an eine Formationsprobe gekoppelt. Das simulierte Bohrloch umfasst das Perforierungswerkzeugsystem und eine oder mehrere Füllscheiben, die ein Volumen des simulierten Bohrlochs aufbrauchen. Die Füllscheiben werden verwendet, um den dynamischen Unterdruck für eine jeweilige Simulation eines Perforierungswerkzeugsystems zu regeln. Eine oder mehrere Messungen, die mit dem Perforierungswerkzeugsystem verbunden sind, können zusammen mit einer oder mehreren Aufnahmen generiert werden, nachdem Sprengladungen des Perforierungswerkzeugsystems zum Detonieren gebracht worden sind. Das Perforierungswerkzeugsystem kann zumindest teilweise auf der Grundlage der einen oder mehreren Messungen und der einen oder mehreren Aufnahmen für den spezifischen dynamischen Unterdruck der Simulation modifiziert werden.
LALTROMARE SOCIAL COOPERATIVE SOCIETY

THE LALTROMARE COOPERATIVE ACTS IN CONCERT WITH THE INSTITUTIONS (EUROPEAN COMMUNITY, REGIONS, MUNICIPALITIES, UNIVERSITIES, EMPLOYMENT OFFICES, MARINE PARKS, TRAINING BODIES) AND RESPECTS THOSE VALUES OF ATTENTION TO THE ENVIRONMENT AND TO THE PEOPLE WHO CONSTITUTE ITS MISSION. THEY SPONSORED THE ‘SCALE WITHOUT STEPS’ PROJECT BY SUPPORTING AND TRUSTING THE COOPERATIVE IN THE DIFFERENT EXPERIENCES THAT LALTROMARE HAS INITIATED: IN THIS WAY, THE COOPERATIVE HAS BECOME A TOOL FOR PUBLIC BODIES; A POINT OF REFERENCE AND A CREDIBLE INTERLOCUTOR AS A DESIGN PARTNER FOR THE REALISATION OF NEW PROJECTS, ACTIVITIES AND SERVICES. FINALLY, IT IS WORTH HIGHLIGHTING HOW THE LIGURIA REGION, L’ARS (REGIONAL HEALTH COMPANY), THE MUNICIPALITY OF SAVONA, IN ADDITION TO THE MOST IMPORTANT ASSOCIATIONS WORKING IN THE FIELD OF DISCOMFORT AND DISABILITY, SUCH AS: A.N.M.I.C. APS A.I.A.S. ONLUS A.I.S.L.A. ONLUS A.I.S.M. ONLUS C.I.P. LIGURIA, U.I.C. ONLUS U.I.L.
P13-24 Diagnostic value of electromyography in evaluation of neural injury in lumbosacral radiculopathies

Methods: This is a prospective interventional study. Consent was taken as protocol. Patients referred for myopathy were included and those with diabetes mellitus and age more than 50 years were excluded from the study. Nerve conduction studies and needle exam (concentric needle) performed according to AANEM criteria for myopathy, in addition cervical paraspinal muscles were assessed and patients were encouraged making neck muscles tense for motor unit assessment. Findings were confirmed from qualified neurophysiologist. For data interpretation SPSS version 16 used, results expressed in percentages. Results: Total 78 patients, 51 females and 27 males were included in the study. Inflammatory myopathic findings noted in 60 (76.92%) and noninflammatory in 18 (23.08%). In inflammatory myopathy group 13 (21.66%) showed fibrillation and positive sharp waves in paraspinal muscles but negative in limbs. Among inflammatory myopathy 9 (15%) and in noninflammatory 3 (16.6%) showed myopathic motor units in paraspinal muscles and not in limb muscles. Conclusion: Paraspinal muscle electromyographic assessment is statistically helpful for further evaluation of myopathic disorders particularly if limb muscle electrography does not show fibrillation potentials, positive sharp waves and myopathic motor units or inconclusive findings. Further muscle biopsy is needed to correlate paraspinal muscle predilection or its early involvement in the disease process.
Immune monitoring for risk stratification in solid organ transplant recipients

Every year ~ 40.000 patients throughout the EU are transplanted a new kidney, lung, liver, heart or another organ. The frequency of clinical complications is relatively high because at present there are no diagnostic tests that help physicians to determine the right dosage of immunosuppressive drugs necessary to avoid both organ rejection and clinical complications caused by infections. 

Lophius Biosciences GmbH has developed I-Scan, a functional immune monitoring test that within 24 h provides important information on the strength of the immune system in solid organ transplant recipients. I-Scan uses a proprietary cocktail of stimulants that selectively stimulate the clinically relevant immune cells in a patient’s blood sample. The detection of the triggered interferon γ (IFN-γ) release provides a qualitative and quantitative measurement of cell-mediated immune function.

The feasibility study performed during Phase 1 will explore issues related to both, the clinical biomarker validation study and the best market entry strategy. Several objectives are pursued in parallel and encompass: 
• Setting up the business plan which includes a competitor as well as a freedom-to-operate analysis and a market entry strategy.
• Selection of clinical study partners  and defining the design of the clinical study, best suited to yield highest clinical evidence
• Obtaining regulatory approval for the planned clinical study and setting a strategy to obtain regulatory approval / CE-Marking for final I-Scan products.

Lophius will apply for Phase 2 funding of a clinical study to validate that I-Scan improves the outcome of SOT patients. This study is likely to take place in Germany, Switzerland and Austria where Lophius has already established firm links to transplantation centers. The study is the logical next step to further grow Lophius to become a global leader in the IVD market for immunomonitoring
Effect of depolymerized mango pulp as a stabilizer in, oil-in-water emulsion containing sodium caseinate

Abstract The effect of pectin in mango pulp in term of reducing sugar (45–100 mg glucose/g fresh weight) on oil-in-water emulsion stability was investigated in systems containing sodium caseinate (0–6% (w/w)) and oil (20% (w/w)). Emulsion stability was evaluated from average droplet size, viscosity and creaming stability. Results showed that emulsion made from enzyme treated mango pulp had small average droplet size which led to more creaming stability than emulsion made from non-enzyme treated mango pulp. Increasing degree of hydrolysis for pectin in mango pulp significantly affected creaming stability (p ≤ 0.05) but had no significant effect on average droplet size of the emulsion (p > 0.05). The emulsion with excellent stability was found that made from depolymerized mango pulp with reducing sugar content of 60 mg glucose/g fresh weight (DP 60) and 2% (w/w) sodium caseinate. In addition, it was found that DP 60 could be used as an alternative stabilizer for oil-in-water food emulsion.
Exploration and Innovation of Excellent Engineers Training Program — Take Harbor Waterway and Coastal Engineering Major as an Example

“Excellent Engineers Training Program” which was proposed by Chinese Ministry of Education is an important plan to train excellent engineers. The major of Harbor Waterway and Coastal Engineering is strongly needed by social and economic development in the recent years. It is both a challenge and an opportunity to carry out the Excellent Engineering Program. This paper firstly made an analysis of problems in the engineering and technical personnel training in China. And it also highlighted the factors when exploring and innovating the training work of Excellent Harbor Waterway and Coastal Engineering Engineers. Moreover, the exploratory work of the major of Harbor, Coastal and Offshore Engineering in Hohai University for “Excellent Engineers Training Program” has been introduced.
Elucidating dendritic cell heterogeneity and functions in metabolic associated fatty liver disease

The increasing clinical and societal burden of metabolic-associated fatty liver disease (MAFLD) coupled with the current lack of therapies highlights the need for a better understanding of the mechanisms driving this disease. In recent years, studies, including my own, have identified that MAFLD is accompanied by a change in the T cell subsets present in the liver and blood. However, the functions and causes of these altered populations remain largely unknown. Conventional dendritic cells (cDCs) function to sample antigens in the periphery and subsequently migrate to the lymph nodes (LNs) where they induce the proliferation and polarisation of naïve T cells, which then home back to the periphery to perform their functions. As such, by manipulating cDC function, we could potentially alter the T cells present in MAFLD and hence improve disease outcome. To date, studies of cDC function in MAFLD have been hampered by our limited understanding of cDC heterogeneity and the lack of specific tools with which to manipulate them in vivo. Building on the cDC expertise of the host lab, the single cell technologies established to dissect heterogeneity, and access to more specific models to target these cells, here, I aim to dissect cDC heterogeneity in the fatty liver. To this end, I will combine the mouse models of the host lab, with my expertise working with human material to identify the conserved features across humans and mice. As MAFLD is associated with an increase in CD8+ T cells, I hypothesize that by manipulating the main cDC subset associated with cross-presentation of antigen to naïve CD8+ T cells, namely the cDC1s, I can manipulate disease progression. Using the novel XCR1-CRE mouse model to specifically target cDC1s in vivo, I will investigate the in vivo functions of these cells in MAFLD and determine their potential for therapeutic intervention to improve patient outcome.
Persia and babylonia: creating a new context for understanding the emergence of the first world empire

The Persian Empire (539-330 BCE) represented a new political order in world history. At its height, it united a territory stretching from present-day India to Libya. It was three times as large and twice as long-lived as the previously most successful polity (Assyria), and it would take 2,000 years before significantly larger empires emerged in early modern Eurasia. 

What explains Persia’s success? This question eludes scholarship due to a lack of evidence and a lack of engagement. Since this Empire unified for the first time in history millions of people under its rule – a condition that became a recurring experience of humanity – understanding Persia’s success transcends its intrinsic relevance to the period in question. 

The principal reason why an effective engagement with this question is presently impossible is the lack of data. The PERSIA AND BABYLONIA project presents a substantial new data set that allows us, for the first time, to contextualize the emergence of the Persian Empire as a complex social process, shifting away from understandings of the Empire as a one-dimensional, state-initiated construct. This data derives from cuneiform textual sources that were produced in Persia’s most important periphery – Babylonia. A key analytical device in our work will be to compare Persian responses to those of the Assyrians, who were unable to establish control of Babylonia a century earlier. By combining a long-term with a deeply contextualized perspective, we will be able to draw out the distinctive efficiency of Persian rule, within the long history of this particular region. In addition to making a significant step towards understanding the emergence of Ancient Persia, we will develop a much-needed research tool for historians of empire and society in the ancient world.
Profit or politics? Understanding renationalizations in Russia

Abstract This study examines firm-level determinants of the government incentives to acquire controlling stakes in private companies. Using a novel hand-collected dataset of 153 largest listed and unlisted Russian companies, I investigate the methods and the rationales of a 2004–2008 wave of selected nationalizations in a post-privatization market. I find robust evidence that formerly privatized and domestically-owned companies in strategically important sectors face the highest risks of corporate control transfers from private to state hands. I also find that the corporate tax evasion is another significant determinant of a firm nationalization. Contrary to commonly held beliefs, there is little evidence that renationalizations in Russia are driven by firm profitability factors: the government neither systematically “cherry-picks” best performers nor addresses market failures by rescuing national champions in financial distress. These results contribute to t'he politics and finance literature by providing new firm-level evidence on the importance of strategic nationalism in the government's decision to intervene into the corporate control structures.
COUPLING DEVICE FOR DREDGING PIPES AND METHOD FOR COUPLING DREDGING PIPES

The invention relates to a pipe connection device (3) for coupling a first end part (4) of a first pipe section (2) to a second end part (4') of a second pipe section (2') to form a pipeline. The pipe connection device comprises a first pipe positioning member (5) arranged to receive the first end part, and a second pipe positioning member (5') arranged to receive the second end part. The first and second pipe positioning members (5, 5') both define a self-centring guiding path formed by a funnel-like shaped pipe positioning member for guiding the respective first and second end parts towards each other. The first and second pipe positioning members are mounted with the first and second self-centring guiding paths coaxial with respect to each other.