SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Water forced in hydrophobic nano-confinement: tunable solvent system

Water is the sustainable solvent of excellence but its high polarity limits the solubility of non-polar compounds. Confinement of water in hydrophobic pores alters its hydrogen bonding structure and related properties such as dielectric constant and solvation power. Whether this special state of confined water can be rendered useful in chemical processes is hitherto underexplored. The original idea of this project is to modulate water solvent properties through hydrophobic nano-confinement. Pressure is applied to force a heterogeneous mixture of poorly soluble molecules and water into hydrophobic nanopores of host material where the lowered polarity of water enhances dissolution. Decompression after reaction causes expulsion of the solution from the pores and spontaneous demixing of reaction products as water returns to its normal polar state.
Temporary dissolution enhancement during confinement is expected to be advantageous to chemical reaction and molecular storage. Development of dedicated hydrophobic nanoporous materials and research methodologies providing in situ characterization of confined water, solutes and host material using NMR, EIS, DRS, X-ray and neutron scattering under static and dynamic conditions are key aspects of this project. Nano-confined water offers a potential alternative to compression for storing CH4 and H2 gas, and opens new opportunities for green chemistry such as aqueous phase hydrogenation reactions which benefit from enhanced hydrogen solubility.
Unprecedented control in time and space over H2O solvation properties in a WATUSO system will enable new technologies with major scientific and societal impact. WATUSO will lead to new insights in water research and deliver new multi-diagnostic characterization tools. WATUSO could revolutionize chemical manufacturing and gas storage and the concept could spill over to many more solvent-based processes. WATUSO will contribute significantly to a greener, more sustainable chemical industry.
Investigation of increased listeriosis revealed two fishery production plants with persistent<i>Listeria</i>contamination in Finland in 2010

SUMMARY In 2010, a marked increase in listeriosis incidence was observed in Finland. Listeria monocytogenes PFGE profile 96 was responsible for one-fifth of the reported cases and a cluster of PFGE profile 62 was also detected. Investigations revealed two fishery production plants with persistent Listeria contamination. It appears likely that the plants were at least partly responsible for the increase of listeriosis. Epidemiological investigation revealed that 57% (31/54) of cases with underlying immunosuppressive condition or medication reported eating gravad or cold-smoked fish. Two public notices were issued by THL and Evira informing which groups were most at risk from the effects of listeriosis and should therefore be cautious in consuming certain products. Systematic sampling of foods and adequate epidemiological investigation methods are required to identify the sources of Listeria infections. Continuous control measures at fishery production plants producing risk products are essential.
Rheological modeling of non-depectinized beetroot juice concentrates

The rheological behavior of non-depectinized beetroot juice concentrate (25, 35, 45 and 55 °Brix) was studied over a wide range of temperature (30, 40, 50, 60, 70 and 80 °C) using a controlled rate, rotational rheometer. From the applied non-Newtonian rheological models, power law model was found to be the best fit with the values of flow behavior index (n) ranging from 0.6182 to 0.9962 showing the shear-thinning nature of beetroot juice concentrate (n < 1). The apparent viscosity was greatly affected by the increased soluble solids’ content at lower temperatures. Activation energy (E
 a
 ) calculated for each concentrated sample was observed to ascend from 14.8 to 25.03 kJ·mol−1 with increase in juice concentration. The exponential model suitably explains the dependency of consistency coefficient (K) on concentration at different temperatures. Combined effect of temperature and concentration on ‘K’ was also examined and conclusively the exponential model was fitted well and a single equation was derived.
 $$ K\, = \,5.59\, \times \,10^{ - 6} \,\exp \,\left( {0.08\,C\, + \,\frac{2652.5}{T}} \right),\quad \quad \left( {{\text{R}}^{2} = 0.996{\text{ and RMSE}} = 0.0004} \right) $$
 where, K is the consistency coefficient (Pa.sn), C is the total soluble solid content in °Brix and T is the temperature in °K.
Application of anin vitroOAT assay in drug design and optimization of renal clearance

1. Optimization of renal clearance is a complex balance between passive and active processes mediated by renal transporters. This work aimed to characterize the interaction of a series of compounds with rat and human organic anion transporters (OATs) and develop quantitative structure-activity relationships (QSARs) to optimize renal clearance. 2. In vitro inhibition assays were established for human OAT1 and rat Oat3 and rat in vivo renal clearance was obtained. Statistically significant quantitative relationships were explored between the compounds' physical properties, their affinity for OAT1 and oat3 and the inter-relationship with unbound renal clearance (URC) in rat. 3. Many of the compounds were actively secreted and in vitro analysis demonstrated that these were ligands for rat and human OAT transporters (IC50 values ranging from <1 to >100 µM). Application of resultant QSAR models reduced renal clearance in the rat from 24 to <0.1 ml/min/kg. Data analysis indicated that the properties associated with increasing affinity at OATs are the same as those associated with reducing URC but orthogonal in nature. 4. This study has demonstrated that OAT inhibition data and QSAR models can be successfully used to optimize rat renal clearance in vivo and provide confidence of translation to humans.
Measuring Outcomes in Rhinosinusitis

Background Rhinosinusitis (RS) is a complex group of disorders characterized by inflammation of the mucosa of the nose and paranasal sinuses. Methods One of the problems with evaluating and treating RS is that there are often difficulties and controversies related to the means of diagnosis, which would prompt appropriate treatment. Results This is particularly true in chronic RS where multiple treatments may be chosen and often these decisions are somewhat empiric and are based on the associated history, symptoms, and prior treatment. This also creates problems with assessing response to treatment where there are multiple tools that are used to diagnose RS and to assess response to both treatment and nontreatment over time. Consistent and reproducible measures of outcome may be lacking. Conclusion The purpose of this study was to describe the various diagnostic criteria that are used to evaluate RS and their role in measuring outcomes.
An Ice-Ocean Forecasting System For Eastern Canadian Waters

An ice-ocean forecasting system for eastern Canadian waters has been developed to provide short-term forecasts of ice concentration, ice thickness, sea surface temperature and other oceanographic variables. The system has been run operationally at Bedford Institute of Oceanography since 2007. Daily forecasts are provided to users in the offshore oil industrial, sea-ice research institutes, and government agencies responsible for search-and-rescue operation and marine shipping. Forecast results in graphic forms are posted on the Internet accessible by the general public. In this paper, the forecast model, forcing data, methods of data assimilation, operational procedure and evaluation of forecast skills are described.
Sams - international partnership on innovation in smart apiculture management services (apiculture = beekeeping)

SAMS enhances international cooperation of ICT and sustainable agriculture between EU and developing countries in pursuit of EU commitment to UN Sustainable Development Goal (SDG N°2) “End hunger, achieve food security and improved nutrition and promote sustainable agriculture”.
Beekeeping with small-scale operations provides perfect innovation labs for demonstration and dissemination of cheap and easy-to-use open source ICT applications in developing countries.
Bee health and sustainable beekeeping are a key for sustainable agriculture worldwide. Risks of depleting honey production threatens livelihoods of beekeepers, but degradation of pollination power of suffering bee colonies threats overall agricultural production and affects entire population.
SAMS allows active monitoring and remote sensing of bee health and beekeeping by developing appropriate ICT solution supporting management of bee health and bee productivity and a role model for effective international cooperation. 
Summarized, SAMS addresses requirements of end-user communities on beekeeping in developing countries. It includes technological improvements and adaptation as well as innovative services creation in apiculture based on advanced ICT and remote sensing technologies.
SAMS increases production of bee products, creates jobs (particularly youths/ women), triggers investments and establishes knowledge exchange through networks. SAMS results are of major interest for stakeholder along the whole value chain of honey production. By cooperation with other networks, SAMS technology will be promoted worldwide to beekeepers as well as data beneficiaries.
SAMS will be implemented in seven workpackages. Project participants in these workpackages are: GIZ, UNIKAS, UNILV, UNIGRA, UNPAD, CVPI, HOLETA and ICEADDIS.
Required project duration conducts 36 months. Necessary EU funding amounts to 1.999.869,25 €
Deciphering the mechanism of the dual functional e3 ligase trim28 in cancer cells

TRIM family proteins are RING-type E3 ubiquitin ligases with important roles in immune responses, autophagy and cellular signalling. They are characterised by the presence of an N-terminal tripartite motif that harbours the catalytic RING domain and a C-terminal variable substrate-binding domain. TRIM28/KAP1 is a unique family member that is better known for its role in transcriptional repression, which is mediated via its C-terminal PHD-Bromo domains. Nevertheless, ubiquitination activity has been described for TRIM28, especially in cancer cells, in conjunction with Melanoma Antigen (MAGE) proteins. MAGE proteins are aberrantly expressed in many cancer types and have been proposed to regulate and activate TRIM28 E3 activity to mediate proteasomal degradation of prominent targets, including p53 and AMPK. Cellular and molecular details of TRIM28 MAGE-dependent ligase activity remain unknown. Furthermore, it is unclear, how the interplay between the two functions of TRIM28 is regulated and how the protein E3 ligase activity is supressed when recruited as part of transcriptional silencing complexes. 
I want to use a multi-disciplinary approach and combine unbiased proteomic studies with in vitro biochemical, biophysical and structural experiments to study MAGE-dependent regulation of TRIM28 E3 ligase activity. I aim to identify cellular signals such as posttranslational modifications and interaction partners that can both modulate MAGE-TRIM28 complexes and regulate the interplay between the transcriptional and the E3 ligase activity. By combining these findings with structural and mechanistic studies, I will uncover how MAGE proteins modulate substrate recognition, E2 recruitment and ligase activity of TRIM28, and create a model of MAGE-TRIM28 function.
Trapping airborne particles by jumping-droplet condensation on superhydrophobic surface

Inhalation of microscale particles can cause severe health issues in respiratory and cardiovascular systems of humans. Trapping airborne particles by water droplets is one of the most widely used methods to reduce the particle concentration in polluted air. However, generating intensive micro-droplets via spraying or ultrasonic atomization normally requires specialized equipment and a large amount of energy. In this project, I propose a novel and cost-effective approach to capture particles by utilizing abundant self-jumping droplets generated during condensation on a superhydrophobic surface. Since the condensation process is ubiquitous and can be found in various heat transfer devices such as air conditioners, the proposed strategy will significantly reduce the expenses and energy costs for particle removal. In particular, to enhance the particle trapping rate, I intend to explore the rational superhydrophobic surface topography that allows continuous jumping-droplet condensation. I will first analyze the condensing droplet wetting dynamics using the cutting-edge confocal microscopy developed by the host lab. The results obtained will help to optimize the surface structures to achieve the durable condensate repellency. Next, I will investigate the effects of jumping droplet characteristics on the particle-droplet interaction from a single-droplet perspective. Finally, I will use my expertise in thermal physics to quantitatively correlate global condensation heat transfer and particle trapping performance. By integrating these interdisciplinary studies, the project will make a conceptual breakthrough in mitigating air pollution without additional energy consumption, and pave the way for the next-generation climate control devices with built-in air purification capabilities.
Accounting for frame of reference and thermodynamic non-idealities when calculating salt diffusion coefficients in ion exchange membranes

Abstract Accurate evaluation of salt diffusion coefficients from transport rate data in ion exchange membranes requires accounting for frame of reference and non-ideal thermodynamic effects. Due to a lack of models and experimental data quantifying membrane ion activity coefficients, it has been impossible to evaluate the impact of non-ideal thermodynamic effects on observed salt diffusion coefficients. Here, a framework is presented that includes both frame of reference (i.e., convection) and non-ideal thermodynamic effects in calculating salt diffusion coefficients in ion exchange membranes. Effective concentration averaged NaCl diffusion coefficients were determined as a function of upstream NaCl concentration in commercial ion exchange membranes from NaCl permeability and sorption measurements via the solution-diffusion model. Frame of reference effects were evaluated using a version of Fick's law that accounts for convection. The factors necessary to account for non-ideal thermodynamic effects were developed using Manning's counter-ion condensation theory. At low upstream NaCl concentrations, frame of reference and non-ideal thermodynamic effects on diffusion coefficients were negligible. However, at higher upstream NaCl concentrations (e.g., >0.1 M), both effects contribute measurably to NaCl diffusion coefficients. Correcting for frame of reference effects increased apparent NaCl diffusion coefficients. However, correcting for thermodynamic non-idealities of the ions sorbed into the membranes reduced apparent NaCl diffusion coefficients. Fortuitously, for the materials considered in this study, frame of reference and non-ideal thermodynamic effects nearly cancel each other.
Assisted living technologies for the health tourism sector

The ALHTOUR project aims to strengthen and stimulate scientific excellence, and innovation capacity in technologies for independent living, applied to the health tourism at UL (Portugal) , by preparing for the set-up of a  “Health Tourism Living Lab”, identified as a key driver for territorial development. 
The Twinning action will activate a process of knowledge transfer which leverages on academic excellence of KUL (Belgium), UM (Netherlands) and UNIMC (Italy), as well as on complementarities and synergies among Smart Specialization Strategies (SSS) of the 4 regions involved. 
In this way, ALHTOUR will help strengthening the triple helix cooperation skills of UL and supports SSS implementation in  the UL region. As a result, this twinning could become an example of territorial development for other regions and knowledge organisations in Europe.
To achieve these objectives, ALHTOUR  is developed in two action phases characterised by: 
- a multidisciplinary approach, supported by social science and humanities disciplines;
- a constant and active involvement of different stakeholders and the business community;
- a mutual learning and cooperation process, to benefit all partnering institutions.

The plan of collaborative activities includes: staff exchanges, academic symposiums, Job shadowing and cross functional mentoring, joint business seminars, lunch & learn events, summer school, Venture Lab on health tourism.

With regards to the Work Programme, ALTHOURT makes a contribution to the priority given to ‘personalising health and care’ as a form of responding to the ‘Health, demographic change and well-being’ societal challenge. Synergies are relevant also within Smart cities and communities. Finally, ALTHOUR is in line with the European Innovation Partnership on Active and Healthy Ageing, the objectives of the Ambient Assisted Living Joint Programme and the attention devoted by the EC to the opportunities offered by Silver Economy.
ROADWAY BARRIER APPARATUS

Roadway barrier apparatus including roadway barrier modules disposed end to end and pivotally connected together by a pivot pin positioned in aligned apertures of connector brackets at the ends of the modules, the pivot pin having a groove and a spring biased hinge pusher member positionable in the groove to limit upward movement of the pivot pin.
The interpretation of differentia during late antique and early christian thought

Logic has often made major progress in historical circumstances that invited fierce debate and confrontation. The development of Christian thought during periods of crisis in the Church is no exception to this rule. This project explores for the first time how the philosophical notion of the differentia, a crucial term in the construction of definition in ancient logic, penetrated Christian thought and became the cardinal idea for the determination of orthodoxy during the theological debates about the nature(s) of Christ in the sixth and seventh centuries of our era, following the Council of Chalcedon (451 CE). 

The standard account explains these debates in terms of different interpretations of what it means for something to exist. The proposed project argues that the differentia came to be regarded as the condition of the possibility for existence as such, as the theologians improved the sophistication of their controversies by adopting and developing the terms of a logical debate among Neoplatonists in late antiquity. The theological debate on the reality and number of the nature(s) of Christ will be seen to rest on the opposition between interpreting the differentia as a real feature of reality–as the Chalcedonians did, or as merely a concept–which is the anti-Chalcedonian position. 

Designed as an interdisciplinary study of the interpretations and the evolution of the notion of the differentia, this project will disclose unknown chapters in the history of both theology and philosophy. At the same it will provide further support for the thesis that doctrinal wars outside philosophy were indeed waged, and settled, by adopting and developing the tools of logic. This strategy may well hold a promise for the doctrinal wars of the present, as well as for new developments in philosophy and logic.
Implementación de la nueva tecnología de cortinas enrollables y su envoltura automática con cintas y tirando en la cubierta

Objetivo del proyecto: El objetivo del proyecto de inversión es implementar una nueva tecnología en el mercado en forma de agricultor en dos variantes: I. «Roller con envoltura de cinta automática» II. La aplicación, propiedad exclusiva de PEMES, de la empresa de Conocimiento Técnico no patentado, permitirá ofrecer un producto caracterizado por ofertas competitivas sin precedentes, parámetros de producción como, entre otros: minimización significativa del producto final, aceleración significativa del proceso de laminación, envoltura y tracción en la cubierta, reducción del volumen de almohada laminada. Como resultado del proyecto, se logrará la plena capacidad de producción, necesaria para ofrecer la innovación de productos resultante de la implementación de los conocimientos técnicos no patentados de PEMES creados como resultado de la investigación interna. La inversión contribuirá positivamente al desarrollo económico de la empresa y de la región. La diversificación de la oferta permitirá crear nuevos puestos de trabajo y orientar las ventas también contribuirá a mejorar la balanza comercial de Polonia.
THE IMPACT OF TYPE Ia SUPERNOVA EXPLOSIONS ON HELIUM COMPANIONS IN THE CHANDRASEKHAR-MASS EXPLOSION SCENARIO

In the version of the SD scenario of SNe Ia studied here, a CO WD explodes close to the Chandrasekhar limit after accreting material from a non-degenerate He companion. In the present study, we employ the Stellar GADGET code to perform 3D hydrodynamical simulations of the interaction of the SN Ia ejecta with the He companion taking into account its orbital motion and spin. It is found that only 2%--5% of the initial companion mass are stripped off from the outer layers of He companions due to the SN impact. The dependence of the unbound mass (or the kick velocity) on the orbital separation can be fitted in good approximation by a power law for a given companion model. After the SN impact, the outer layers of a He donor star are significantly enriched with heavy elements from the low-expansion-velocity tail of SN Ia ejecta. The total mass of accumulated SN-ejecta material on the companion surface reaches about > 10e-3 M_sun for different companion models. This enrichment with heavy elements provides a potential way to observationally identify the surviving companion star in SN remnants. Finally, by artificially adjusting the explosion energy of the W7 explosion model, we find that the total accumulation of SN ejecta on the companion surface is also dependent on the explosion energy with a power law relation in good approximation.
Deconstructing the past: modelling the locomotion of miocene hominoids through computational techniques

The challenge of better knowing the complex relationship between bone's morphology and function has yielded tens of articles since the beginning of the last century and is essential for making positional behavioural inferences on fossil taxa. Despite its relevance, the form-function relationship is still poorly understood. Based on this premise, this project focuses on deciphering the functional loading environment and its influence on skeletal design in the hindlimb of living primates and shedding light on the locomotor evolution of fossil apes and early hominins. The fossil apes included in this project constitute key taxa for understanding the positional behaviour evolution within the Hominoidea (the apes and humans clade), which has important implications for a better knowledge of the evolutionary pathway that led to the specialized locomotor types of extant apes and humans (specialized antipronograde behaviours such as below-branch suspension and human terrestrial bipedalism). To accomplish the aims, this project will rely on diverse, multidisciplinary and innovative techniques, including biomechanical and engineering approaches (e.g., multibody dynamics analysis, computer optimization, machine learning and data science), phylogenetic comparative methods, and collection of experimental data (e.g., recording of live primates kinematics). This project also involves an important component of training for the applicant and several short stays to gain a diversified and unique set of skills and knowledge on the field of paleoprimatology and evolutionary biology. Hence, this project will extend our knowledge on the bone's form-function relationship, as well as the origin, tempo and mode of the hominoids positional behaviour evolution, including key long-lasting questions related to the origins of human bipedalism.