SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Exploring the trade-space of MIMO SAR

The term MIMO SAR is used for Synthetic Aperture Radar (SAR) systems utilizingmultiple-receive andmultiple-transmit channels (Multiple-Input Multiple Output: MIMO). The trade-space for such SAR systems includes the instrument and antenna parameters taking into consideration the techniques, i.e. the operation modes of the radar. The purpose of exploring this trade-space is to improve and optimize the performance of the system, described through the performance parameters. The aim of this paper is to show examples of how MIMO SAR offers new and unexpected ways of trading the system and performance parameters versus each other. Adequately exploring the trade-space yields a high flexibility and allows to simultaneously improve multiple performance parameters; a feature not available in conventional single channel SAR systems. The content of this paper is considered novel in the sense that it deals with highly advance SAR techniques.
Population dynamics in the southeast european neolithic: prehistoric archaeology and palaeogenomics

“Population dynamics in the Southeast European Neolithic” is an interdisciplinary project, focusing on the Neolithic transition, a major turning point in human history, when people domesticated plants and animals, and built the first permanent villages. The work of the Palaeogenetics Group in Mainz shows that the first European farmers probably migrated from Anatolia, one of the first regions to adopt agriculture after food plants and animals were domesticated in Southwest Asia. 
The question that this project addresses is how, in a practical sense, early farmers interacted with foragers, as well as with other farmers, during the initial phases of agricultural spread in Southeast Europe. For instance, is there any evidence that early farmers and foragers lived side by side? If so, did they admix to any significant extent? What was the population structure of early farming communities? And how did the structure of Neolithic settlements affect farmer-forager and farmer-farmer interactions? Specifically, the project will test archaeologically-informed population models and provide context in terms of where ancient DNA results produced by the Palaeogenetics Group sit archaeologically. This will help to lead the field of palaeogenetics from its continental and large-scale oriented perspective towards finer-scale population genetic inference at regional, site-specific or even household levels. For archaeology, this is an opportunity to reclaim the field of prehistoric migrations and engage with the latest results of aDNA research. 
In the course of the project, I hope to establish myself as an archaeologist who is able to critically evaluate approaches and techniques used in statistical genomics, in order to help bridge the gap and bring prehistoric archaeology and palaeogenomics closer together.
Canonical transformations and loop formulation of SU(N) lattice gauge theories

We construct canonical transformations to reformulate SU(N) Kogut-Susskind lattice gauge theory in terms of a set of fundamental loop & string flux operators along with their canonically conjugate loop & string electric fields. We show that as a consequence of SU(N) Gauss laws all SU(N) string degrees of freedom become cyclic and decouple from the physical Hilbert space ${\cal H}^p$. The canonical relations between the initial SU(N) link operators and the final SU(N) loop & string operators over the entire lattice are worked out in a self consistent manner. The Kogut-Susskind Hamiltonian rewritten in terms of the fundamental physical loop operators has global SU(N) invariance. There are no gauge fields. We further show that the $(1/g^2)$ magnetic field terms on plaquettes create and annihilate the fundamental plaquette loop fluxes while the $(g^2)$ electric field terms describe all their interactions. In the weak coupling ($g^2 \rightarrow 0$) continuum limit the SU(N) loop dynamics is described by SU(N) spin Hamiltonian with nearest neighbour interactions. In the simplest SU(2) case, where the canonical transformations map the SU(2) loop Hilbert space into the Hilbert spaces of hydrogen atoms, we analyze the special role of the hydrogen atom dynamical symmetry group $SO(4,2)$ in the loop dynamics and the spectrum. A simple tensor network ansatz in the SU(2) gauge invariant hydrogen atom loop basis is discussed.
Hypercube: gram scale production of ferrite nanocubes and thermo-responsive polymer coated nanocubes for medical applications and further exploitation in other hyperthermia fields

This project aims at the scale up production, characterization, future commercialization and clinical translation of magnetic iron oxides nanocubes of high magnetic and structural quality and the design and production of an in-flow set up for the further functionalization of the nanocubes with a thermo-responsive (TR) polymer shell. The nanocubes and TR-nanocubes are aimed to be used primarily as heat mediators in magnetic hyperthermia (MH) and as heat-mediated drug agents for the delivery of chemotherapeutic drugs in a heat triggered-mediated chemotherapy for the treatment of tumors. Their use as contrast agents in magnetic resonance imaging (MRI) and magnetic particle imaging (MPI) stands as secondary applications  and it will also be relevant in this project. Indeed, given the control over the materials, the scale up synthesis of nanocubes and the in-flow production of TR-nanocubes, we will deliver an unprecedented benchmark scaled product of nanocubes with optimal magneto-heat properties that shall ensure the transition of such materials towards the market and the clinics. In comparison to the standardly used and commercially available magnetic nanoparticles, the high magneto-heat performances at clinically safe magnetic radiofrequency, of such nanocubes will impact the treatment of tumor by MH, by multiple aspects: i) requiring less dose of magnetic materials to be injected intratumorally; ii) unique actuation of dual combination therapy of MH and local heat-triggered drug release, which also will favor a more efficacious therapy at reduced dose of magnetic materials; iii)  further degradation and clearance of the heat-mediator nanocubes thus enabling the further investigation of tumour progression by MRI, overcoming the current limitation of iron oxide nanoparticles now employed in MH for the treatment of Glioblastoma Multiforme. Instead, their magnetic response at frequency range of 20-40 kHz will make them appealing as contrast agents in MPI.
NOVEL METHOD FOR SYNTHESIS OF (2S, 3AS, 7AS)-1-[(S)-ALANYL]-OCTAHYDRO-1 H -INDOLE-2-CARBOXYLIC ACID DERIVATIVES AND USE FOR SYNTHESIS OF PERINDOPRIL

The invention concerns a method for industrial synthesis of compounds of formula (I), wherein: R1 represents a hydrogen atom or a linear or branched C1-C6 alkyl group or benzyl, and R2 represents a group protecting the amino function. The invention also concerns the use of same for industrial synthesis of perindopril of formula (II) and its pharmaceutically acceptable salts.
Bridging large and small scales of water models using hybrid Molecular Dynamics/Fluctuating Hydrodynamics framework

This thesis presents a two-dimensional water model investigation and development of a multiscale method for the modelling of large systems, such as virus in water or peptide immersed in the solvent. We have implemented a two-dimensional ‘Mercedes Benz’ (MB) or BN2D water model using Molecular Dynamics. We have studied its dynamical and structural properties dependence on the model’s parameters. For the first time we derived formulas to calculate thermodynamic properties of the MB model in the microcanonical (NVE) ensemble. We also derived equations of motion in the isothermal–isobaric (NPT) ensemble. We have analysed the rotational degree of freedom of the model in both ensembles. We have developed and implemented a self-consistent multiscale method, which is able to communicate micro- and macro- scales. This multiscale method assumes, that matter consists of the two phases. One phase is related to micro- and the other to macroscale. We simulate the macro scale using Landau Lifshitz-Fluctuating Hydrodynamics, while we describe the microscale using Molecular Dynamics. We have demonstrated that the communication between the disparate scales is possible without introduction of fictitious interface or approximations which reduce the accuracy of the information exchange between the scales. We have investigated control parameters, which were introduced to control the contribution of each phases to the matter behaviour. We have shown, that microscales inherit dynamical properties of the macroscales and vice versa, depending on the concentration of each phase. We have shown, that Radial Distribution Function is not altered and velocity autocorrelation functions are gradually transformed, from Molecular Dynamics to Fluctuating Hydrodynamics description, when phase balance is changed. In this work we test our multiscale method for the liquid argon, BN2D and SPC/E water models. For the SPC/E water model we investigate microscale fluctuations which are computed using advanced mapping technique of the small scales to the large scales, which was developed by Voulgarakisand et. al.
Cooled blade or vane for a gas turbine

A cooled blade or vane for a gas turbine has a main blade or vane part which starts from a blade or vane root and a blade or vane shank and has a leading edge and a trailing edge, as well as, inside the main blade or vane part, a plurality of cooling ducts, which extend in the radial direction, are connected in series in terms of flow and of which a first cooling duct has a main stream of a cooling medium flowing through it along the leading edge. A second cooling duct has a main stream of a cooling medium flowing through it along the trailing edge, from the blade or vane root to the tip of the main blade or vane part. The outlet of the first cooling duct is in communication, via a first diverting region, a third cooling duct arranged between the first and second cooling ducts, and a second diverting region, with the inlet of the second cooling duct.
NYLON CARPET FIBERS HAVING BLEACH RESISTANCE

The present invention relates to a nylon yarn of a finely dispersed melt blended polymer alloy having i) a polyamide component selected from polyhexamethyleneadipamide, polycaprolactam and mixtures thereof, and ii) a nylon 11 component; wherein the polyamide component is the major component by weight of the total melt blended polymer and wherein the polyamide component has a viscosity of about 2.6 IV or more as measured in 96% sulfuric acid. The resulting nylon yarn shows improved bleach resistance. The present invention also relates to processes of producing the yarn and nylon carpets comprising the yarn described above.
Agency and Structure in Social Mobility in the Light of Individualization: Empirical Research Review

The article addresses the issue of empirical investigation of individualization in life-course. The theory of individualization implies that the significance of social structure in individual life-course diminishes, giving way to the agency of personal preferences and skills. Thus, the theory raises an issue of structure-agency dynamics in life-course, and poses a methodological challenge for research design to take both social structualization and individual action into account. Empirical research on individualization varies in how it meets this challenge. The review streamlines the main topics, the analytical tools, and the empirical evidence from this research. We identify three main currents in empirical research on individualization. Firstly, the research is concerned with the changing role of agency in life-course, raising a question of its significance vis-a-vis structure. Secondly, individualization is approached through the lens of a social inequality critique; this type of research investigates socio-economic- and gender-patterning in individualization. Finally, individualization is understood as a leading principle of modern labor markets, and social welfare institutions. The article highlights the inconsistencies and tensions in the empirical evidence. On the micro-level, individualization manifests itself as a change in biographical orientations, that is, the increasing value of independence, ambition, and flexibility encouraged by modern labor markets and social safety-net design. On the macro-level, it is embodied in the increasing differentiation and destandardization in life-course. Yet, an ability to make biographical plans a reality continues to depend on social conditions. The article discusses the analytical categories which help comprehend these tensions; structured individualization, default/passive and developing/active individualization, and biographical surfing. The scope of the review goes beyond youth studies where the issue of individualization is the most commonly discussed, and spans empirical evidence on individualization found in the sociology of adulthood and older age, and social research on the welfare state, education, and labor markets.
Implementation of crispr/cas9 technology in melon to edit fruit ripening and cmv resistant genes

Meeting with global food demand is one of the main priorities in the 2016-17 work programme of H2020. Virus diseases are
among the main causes of crop production losses, being Cucumber mosaic virus (CMV) the virus with broadest host range.
On the other hand, post-harvest losses are estimated to account for 15-40% of fruit and vegetable production worldwide. In
this scenario, several efforts are ongoing to identify genes underlying fruit quality and production such us those related with
climacteric ripening and CMV resistance
Melon (Cucumis melo L.) is one oft he most economically important group of vegetable crops after Solanaceae, and has
emerged as a crop model for important biological traits due to its phenotypic variability and the the availability of genetic and
genomic resources. Previous studies at the host group have identified and mapped genes involved in the regulation of
climacteric fruit ripening and in a novel mechanism for CMV resistance in this species. MeloCRISP proposes to progress our
current understanding on the genomic control of these important agronomic traits by functionally validating the identified
candidate genes. The CRISPR/Cas9 system will be implemented for the first time in this species and used for precise gene
editing. In order to delay or impair fruit ripening in climacteric varieties, a gene knockout strategy will be approached. On the
other hand, a precise nucleotide substitution in the resistance to CMV region (cmv1) will be performed to generate CMV
resistant plants
The expected outcome is the development of non-transgenic melon CMV resistant plants and varieties with improved fruit
quality. This inter-sectorial and multidisciplinary project involves the engagement of a seed industry which will guarantee the
transfer of the results to the seed market, ultimately leading to a high impact in the agriculture and food industry sector.
Moreover, the implementation of CRISPR/Cas9 will become a valuable tool for melon breeding programs.
ADAPTIVE PROCESSING FOR SEQUENCE ALIGNMENT

Disclosed are various embodiments for adaptive processing for sequence alignment. In one embodiment, among others, a method includes obtaining a query sequence and a plurality of database sequences. A first portion of the plurality of database sequences is distributed to a central processing unit (CPU) and a second portion of the plurality of database sequences is distributed to a graphical processing unit (GPU) based upon a predetermined splitting ratio associated with the plurality of database sequences, where the database sequences of the first portion are shorter than the database sequences of the second portion. A first alignment score for the query sequence is determined with the CPU based upon the first portion of the plurality of database sequences and a second alignment score for the query sequence is determined with the GPU based upon the second portion of the plurality of database sequences.
Compact thz lasers based on graphene quantum dots

The ambition of this project is to open new horizons in the field of graphene-based devices for THz technology. The major objective is to develop compact THz amplifiers and lasers operating at room temperature, analogous to the concept of semiconductor lasers in the visible and telecom wavelength range. 
THz radiation is extremely attractive for fundamental investigations of matter and emerging applications including, for example, security screening, medical imaging and spectroscopy. However, the THz spectral range remains one of the least exploited spectral regions, mainly due to the lack of compact powerful sources. The development of the typical semiconductor-laser scheme emitting at THz frequencies has been seriously hampered by the absence of an appropriate material with a sufficiently small bandgap. The LEON project addresses this technological and scientific blocking point with new semiconductor-laser schemes for THz emission centered on the integration of graphene-based materials. 
Indeed, graphene is potentially an excellent candidate for a THz semiconductor-laser model owing to its ‘zero’ bandgap. However, non-radiative recombination mechanisms, especially Auger recombination, reduce the lifetime of the optical gain to few hundreds of femtoseconds. This phenomenon drastically limits the feasibility of a THz laser. In order to suppress these detrimental non-radiative processes, a new concept is needed. The project proposes to exploit the full discretization of electronic states in graphene quantum dots. This high-risk high-gain project will provide important and far-reaching scientific advances, which cannot be achieved with the current state-of-the-art approaches.
This project has three major cornerstones: i) the demonstration of THz amplifiers based on graphene quantum dots, ii) the demonstration of THz lasers based on graphene quantum dots in a microcavity, iii) the exploitation of these THz amplifiers/lasers for security and communication applications.
COMBINATORIAL PROCESS FOR PREPARING THIAZOLIDINONE LIBRARIES

This invention relates to a novel diverse combinatorial library of thiazolidinone compounds and to an apparatus providing a readily accessible source of individual members of the library. The apparatus can be used in assay kits and as a replaceable element in automated assay machines.
In vitro ultrasonic assessment of the biomechanical quality of the interface surrounding a dental implant

Dental implants are widely used clinically and have allowed considerable progresses in oral and maxillofacial surgery. However, implant failures, which may have dramatic consequences, still occur and remain difficult to anticipate. Accurate measurements of implants biomechanical stability are of interest since they could be used to improve the surgical strategy by adapting the choice of the healing period to each patient. Empirical methods based on palpation are still used by dental surgeons to determine when the implant should be loaded because it remains difficult to monitor bone healing in vivo. The objective of this study is to investigate the potentiality of a quantitative ultrasound method to assess the biomechanical stability of a dental implant in vitro. A 10 MHz contact transducer is located at the implant extremity. For each ultrasound measurement, a quantitative indicator I is derived based on the time variation of the amplitude of the rf signal. Ten implants are initially completely inserted in the proximal part of a bovine humeral bone sample. The 10 MHz ultrasonic response of the implants is then measured and an indicator I is derived based on the amplitude of the rf signal obtained. Then, the implants are unscrewed by 2π radians and the measurement is realized again. The procedure is repeated and the indicator I is derived after each rotation of the implants. Analysis of variance (ANOVA) (p<10− 5) tests revealed a significant effect of the amount of bone in contact with the implant on the distribution of the values of I. The results show the feasibility of QUS techniques to assess implant primary stability in vitro. This study paves the way for the development of a new biomechanical approach in oral implantology.
Impact assessment of dam construction and forest management for Japanese macaque habitats in snowy areas

Japanese macaques (Macaca fuscata) in their northernmost habitats represent a keystone species and play a central role in heavy snowfall ecosystems. However, distributions have been restricted by pre-war hunting, and populations are facing issues of natural forest losses caused by new dam constructions and massive conifer plantations. In the present study, we predicted the influences of these environmental conditions on macaque habitats during each season, and evaluated the effect of natural forest restoration as a mitigation measure. We constructed multiple habitat suitability models on the basis of different forest change scenarios, by using maximum entropy modeling (Maxent). We predicted the influence of each scenario by calculating the habitat unit (habitat quality × habitat quantity). We made the following predictions: (1) the influences of environmental conditions on habitat models vary seasonally, but dam construction destroys the optimum macaque habitats in every season; (2) restoration of conifer plantations to semi-natural forests does not always contribute to the improvement of total habitat unit, except in snowy seasons; and (3) in comparison with encouraging natural forest restoration in plantation areas and maintaining the standard-rotation plantation management, the implementation of long-rotation plantation in existing plantation areas provides more suitable alternative habitats for macaques in non-snowy seasons.
Single-Center Experience and 1-Year Follow-up Results of “Sandwich Technique” in the Management of Common Iliac Artery Aneurysms During EVAR

Abdominal aortic aneurysm (AAA) accompanied by common iliac artery (CIA) aneurysms requires a more demanding procedure owing to the difficulties in obtaining an adequate distal landing zone for the stent-graft limb(s), a potential site of endoleak. The "sandwich technique" is a procedure to increase EVAR feasibility in the setting of adverse or challenging CIA anatomy. Its main advantages include no restrictions in terms of CIA diameter or length or internal iliac artery (IIA) diameter, no need to wait for a specific stent-graft. Our purpose is to describe our single-center experience and one year follow-up results of this new procedure.From April 2009 to June 2010, the sandwich technique was performed in our institution in 7 patients treated for AAA and unilateral CIA aneurysms (n. 5) or bilateral CIA aneurysms (n. 2). Inclusion criteria were the presence of unilateral or bilateral CIA aneurysm (independently from its diameter), IIA artery measuring up to 9 mm in its maximum diameter, not dilatation of IIA and EIA.The mean follow-up length was 15 months (range: 14-20 months). All stent-implanted iliac branches remained patent on 1 year follow-up and IIA flow was preserved. None of the patients had symptoms of pelvic ischemia. CT scan follow-up showed aneurysm shrinkage in five patients, without any sign of endoleaks in all cases.In selected cases, the "sandwich technique" showed good outcomes confirming to be a safe and easy to perform way to overcome anatomical constraints and expanding the limits of EVAR.