SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
BRANDI TISCHLEREI SAS – VON BRANDI ENRICO

DIES IST EINE INVESTITION FÜR DIE ENTWICKLUNG DES UNTERNEHMENS DANK DES KAUFS INNOVATIVER UND EFFIZIENTER MASCHINEN, DIE EINE AUSWEITUNG DER TÄTIGKEIT UND DAMIT DES UMSATZES UND DES GEWINNS DES UNTERNEHMENS ERMÖGLICHEN KÖNNEN. ES WIRD INSBESONDERE DER KAUF EINER GUILLOTINESCHERE, EINES RAUCHSAUGERS, EINES BOHRERS, EINER SCHLEIFMASCHINE, EINER PRESSE UND SCHLIESSLICH EINER BUCHHALTUNGSSOFTWARE ERWARTET. DARÜBER HINAUS GIBT ES AUCH EINE INVESTITION IN BAUARBEITEN, DA DAS LABOR, IN DEM DIE TÄTIGKEIT DURCHGEFÜHRT WIRD, KEINEN RAUM FÜR DIE TATSÄCHLICHE BÜRONUTZUNG HAT UND DIE DIENSTLEISTUNGEN IN EINEM NAHE GELEGENEN RAUM SIND, SO DASS DIE KOSTEN GEPLANT SIND, UM EINEN ANGRENZENDEN RAUM ZU BAUEN, IN DEM SIE DIE DIENSTLEISTUNGEN DER UMKLEIDERÄUME UND EINES BÜROS AUSFÜHREN KÖNNEN. DIE INTERVENTION WIRD ES DEM UNTERNEHMEN ERMÖGLICHEN, EFFIZIENTER ZU WERDEN UND IN DER LAGE ZU SEIN, ALLE PHASEN DES PRODUKTIONSPROZESSES INTERN DURCHZUFÜHREN, OHNE SICH AUF EXTERNE UNTERNEHMEN VERLASSEN ZU MÜSSEN.
Optimizing software rejuvenation policy based on CDM for cloud system

The ever-increasing cloud-based systems are suffering progressive performance degradation due to internal accumulated errors and external security attacks. Software rejuvenation is a preventive maintenance policy to solve this problem. However, an ineffective rejuvenation policy usually causes high resource consumption and system cost loss. To guarantee the high availability and minimize the maintenance cost in the cloud-based system, a cost-effective rejuvenation policy is proposed based on cumulative damage model (CDM) in this paper. With our proposal, prior to system failure diagnosis, the system is managed to be rejuvenated either at a predetermined time or at a damage threshold level, whichever occurs first. Further, the system cost rate function is deduced, and an optimal rejuvenation period is derived aiming to minimize the maintenance cost. Experimental results show that the proposed rejuvenation policy is highly effective in term of great reduction on system cost rate.
Targeting the brain sigma-1 receptor: a paradigm shift for the treatment of neuro-degenerative disorders

An increasingly aging population suffering from neurodegenerative diseases represents one of the biggest challenges for Western societies. Alzheimer’s disease (AD) is the most prevalent neurodegenerative disease with over 50 million patients worldwide and an estimated cost of 1 trillion euros in 2018. In addition, orphan neurodegenerative diseases such as Amyotrophic Lateral Sclerosis (ALS) have a comparably urgent need for treatment, because of the severity and life changing effect of the motor symptoms (muscle spasms, speaking and swallowing problems, full paralysis and lethality). As current treatments are only symptomatic and fail to slow down the disease progression, there is a pressing need for novel effective disease-modifying treatments. 

SigmaThera is a French company that tries to address the need for effective treatments for neurodegenerative diseases by focusing on the repositioning of drug candidates: applying the proven qualities of previously developed drugs for new diseases. For our lead compound SIT-161 with an excellent safety profile in humans (the candidate was abandoned after original Phase 2 trials for major depression) we have obtained impressive proof-of-concept data and patent protection for the treatment of neurodegenerative diseases, including AD & ALS. The drug targets a brain sigma-1 receptor, a critical regulator of multiple processes in neurodegeneration and provides unique efficacy and safety compared to other competing candidates in the pipeline. The high commercial potential of the drug is reflected in the €6.2B total addressable market and projected peak sales of €2B. In the NeuroPa project, SigmaThera will investigate market positioning, clinical and regulatory feasibility, future patent strategy and investor strategy to bring this promising asset close to market implementation.
Challenges for scholarly business research in Latin America

Abstract Nations consider R&D a fundamental way to spur business innovation, increase the international competitiveness of domestic firms, achieve higher levels of economic growth, and increase the social welfare of its citizens. The empirical evidence indicates that, in the Latin America region, investment in R&D is comparatively low, largely depends on public funds, and is highly concentrated in academic research with limited business applications. Empirical evidence suggests a lack of connection in the region between those who produce knowledge (academia) and those who use that knowledge (business practitioners). This paper argues that business schools in the region have a role to play filling this gap by conducting more research with real-world business applications and by fostering innovative entrepreneurship among business school students.
Integration of sustainability labels into Mediterranean tourism policies

Due to the growing need for responsible use of natural and cultural resources, increasing competition in tourism sector and changing consumption patterns, Mediterranean destinations are facing: 

1) Constant demand to improve the quality of tourism offer.

2) Need to strengthen cooperation between tourism providers and local community.

3) Necessity to communicate with the visitors. In sparsely populated, island and protected areas these challenges need to be addressed with greater attention due to specific socio-economic features and increased vulnerability.Tourism sustainability certification is one of the effective instruments which addresses these challenges and shows destination’s commitment to follow the principles of sustainable development. 

It is a tool for improvement of tourist offer, community building and marketing.The overall objective of the LABELSCAPE is thus to develop mechanisms for integrating sustainability labels in wider tourism policies, and to provide support for destination-based initiatives in the certification process. Project capitalises on the existing certification initiatives. It addresses also the latest challenges of certified destinations and businesses: recognisability, complementarity with User Generated Content and digital transformation. LABELSCAPE objectives will be achieved through “Exchange of Experience” workshops, online capacity building platform, policy-change actions in 8 territories and transferable policy recommendations.
Study on the Effects of Different Diluents on the Quality of Boar Sperm Stored at 4

[Objective]This study was designed to develop a method of liquid storage of boar sperm at 4 ℃ using the modified BF5 diluent with BSA and N-acetyl-D-glucosamine(mBF5).[Method]Boar sperm were stored in LEN,BF5 and mBF5 diluents at 4 ℃ for 5 days,and sperm motility,acrosome morphology,viability and ATP were examined according to preservation period.[Result]The results showed that there were no significant differences in sperm motility among the three diluents from 1 day to 2 days stored at 4 ℃.However,the sperm motility showed significant differences among the three diluents after 3 days stored at 4 ℃.The sperm motility in mBF5 diluent was higher than that in LEN and BF5 diluents after 3 days of storage.The percentage of normal acrosome in mBF5 and BF5 diluents was higher than that in LEN diluent from 1 day to 5 days stored at 4 ℃.However,the percentage of normal acrosome in mBF5 diluent was higher than that in BF5 diluent after 5 days stored at 4 ℃.The percentage of sperm viability in mBF5 diluent was higher than that in LEN and BF5 diluent from 1 day to 5 days stored at 4 ℃.The percentage of sperm viability declined steadily from 1 day to 5 days stored in the three different diluents,respectively.Sperm ATP in mBF5 diluent was higher than that in LEN and BF5 diluents from 1 day to 5 days of storage.Sperm ATP declined rapidly after 5 days of storage in the three different diluents,respectively.[Conclusion]It was confirmed that boar sperm could be stored in mBF5 diluent at 4 ℃ for 5 days and showed higher motility,normal acrosome,sperm viability and sperm ATP concentration compared with that stored in LEN and BF5 diluents.
Cityscape: city-level cyber-secure multimodal transport ecosystem

With the emergence of the digitization of information, ICT infrastructure and communications gave an unprecedented push towards the realization of truly interconnected passenger transport ecosystems at city-level. The emerging notion of multimodality supports a plethora of diverse transport services, typically offered from a central location. There however, the complex interconnected infrastructures ease the cyber-threats propagation while the underlying mosaic of fleets, personal hand-held devices and non-standardized data types increase the system's attack surface and require the authorities collaboration to proactively handle severe incidents.
CitySCAPE leverages the skills and mature technology of its 15-partner consortium to systematically explore all different cybersecurity dimensions of multimodal transport. These dimensions will drive a characterization of the cyber-threats in the ICT multimodal transport, extended to the close-by power and financial sector. Innovative software tools will be introduced to estimate the threats propagation in the system. Then, CitySCAPE will realize a modular software toolkit enabled to be seamlessly integrated into any multimodal transport system to: a)detect suspicious traffic-data values and identify persistent threats; b)evaluate an attack's impact in technical and notably in financial terms; c)combine external knowledge and internally-observed activities to enhance the predictability of zero-day attacks; d)instantiate a networked overlay to circulate informative notifications to CERT authorities and support their interplay. The CitySCAPE solution will be tested over a timely set of use-cases involving ticketing applications, cyber-fraud and location data in the regional transport system of two European cities, where extensive experiments will showcase its effectiveness. The findings will steer training sessions of expert/non-expert audience and shape a strong standardization contribution to security (labelling) protocols.
A parametric study on water-entry of a twin wedge by boundary element method

High speed catamarans are used for pleasure, racing as well as passenger transportations. Optimal design of these crafts requires knowledge of sea loads exerted on their structures. The total load may be estimated by integration of loads exerted on a series of two-dimensional sections along the hull. In order to access the cross-sectional loads, the problem may be simplified to solve the water-entry problem of a twin hull. In this paper, water-entry problem of a twin wedge at constant vertical water-entry speed is studied. The problem is solved in the framework of potential theory using boundary element method where gravity effect on the flow is neglected. A simplified model based on Wagner theory is employed. Free surface elevation and pressure distribution on the body in different deadrise angles have been evaluated. A parametric study has been done to investigate effects of deadrise angle, distance between demi-hulls and free surface elevation on maximum pressure coefficient. Finally, a regression formula for maximum pressure coefficient has been proposed. Results of parametric study reveal that as time advances the interaction between two demi-hull gets more severe, besides the interaction effect on pressure coefficient is nonlinear.
ELECTRONIC REAR-VIEW DEVICE

The subject of the invention is a rear-view device for a vehicle (1), comprising at least one camera (2) having a field of view (Xo) covering a defined area of the surroundings of the vehicle (1) and centred on an optical axis (20, Fz), and an electronic display system (3) for display on a video screen (4) of an image (I) of said area of the surroundings recorded by the camera (2). According to the invention, the camera (2) is stationary with a defined orientation of its optical axis (20, Fz) and the electronic display system (3) includes image processing means (31) capable, on the basis of an overall image (Io) recorded by said camera (2), of displaying on the video screen (4) a simulated image (h) matched to the driving conditions at a given instant, said simulated image (h) being centred on a virtual optical axis (Fzi), the orientation of which may be adjusted relative to that of the optical axis (Fz) of the camera (2).
NOVEL COMPLEXES AND THEIR COMPOSITIONS

This invention provides inclusion complexes of Taxol {[2aR-[a alpha ,4 beta ,4 alpha beta ,6 beta ,9 alpha ( alpha R*, beta S*,) 11 alpha ,12 alpha , 12a alpha , 12b alpha ,]]- beta -(benzoylamino)- alpha -hydroxy-benzene-propanoic acid 6,12-b-bis(acetyloxy)-12-(benzoyloxy)-2a, 3, 4, 4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclo-deca-[3,4]-benz-[1,2-b]-oxeth-9-yl-ester]} or Taxotere (butoxycarbonyl-10-desacethyl-N-debenzoyl-Taxol) or Taxus extracts formed with a cyclodextrin derivative and a co-solvent. The molar ratio of Taxol, Taxotere or Taxus extract to cyclodextrin is 1:(10-65), preferably 1:(30-40). This invention relates to pharmaceutical composition with increased water-solubility and stability. This invention provides the process for the preparation of an inclusion complex of Taxol or Taxotere or a brevifolia extract of Taxus formed with a cyclodextrin derivatice and a co-solvent. This invention relates to pharmaceutical composition, containing as active ingredient an effective amount of an inclusion complex of Taxol or Taxotere or a Taxus brevifolia extract formed with a cyclodextrin derivative, preferably heptakis-2,6-0-dimethyl- beta -cyclodextrin, random methylated beta -cyclodextrin, succinylmethyl- beta -cyclodextrin and a co-solvent together with usual filling, diluting and other auxiliaries generally used in the pharmaceutical industry. This invention provides pharmaceutical compositions comprising an inclusion complex of Taxol, Taxotere or Taxus extracts formed with a cyclodextrin or a cyclodextrin derivative as active ingredient, they further contain ethanol or an ethanol-water mixture. Accordingly composition of this invention may be administered for the treatment of human cancer.
Neutral Caregivers or Military Support? The British Red Cross, the Friends’ Ambulance Unit, and the Problems of Voluntary Medical Aid in Wartime

During the First World War the British Red Cross Society (BRCS) served as the coordinating body for voluntary medical aid giving in Britain. Among the many units which came within its purview was the Friends' Ambulance Unit (FAU), formed by a group of young men whose desire to serve their nation in wartime conflicted with their pacifist principles. Both the BRCS and the FAU were wracked by ideological conflicts in the years which preceded and throughout the war. These struggles over voluntarist identity highlight the contested meanings of service and conscience in wartime. Through a critical examination of the language of official histories and biographies, this article will argue that the war formed a key moment in the relationship between the British state and voluntary medical aid, with the state's increasing role in the work of such organizations raising questions about the voluntarist principles to which aid organizations laid claim. The struggles that both organizations and individuals within them faced in reconciling the competing pressures that this new relationship created form a legacy of the war which continues to have important implications for the place of medical voluntarism in wartime today.
METHOD TO ENABLE CUSTOMERS TO RESPOND TO PRICES IN A POOL TYPE ENERGY MARKET

A merchant and a customer have an agreement for the trading of energy units wherein the customer pays a contracted sum and the applicable wholesale market pool price for excess units of energy and receives the wholesale market pool price for unused units of energy. A system monitors and controls the energy usage of the customer. The system includes a metering means (105), a communication means (123, 124) receiving pricing information, a computing means (103) accumulating information from the metering means and communication means and determining a preferred trading outcome, and switching means controlling energy supply to the energy consuming devices to achieve the preferred trading outcome.
(14508.17092020.172000757) LIBRA LASER INNOVA

RENEWAL OF LASER MACHINES USED FOR OWN PROCESSING?COMPANY, IN ORDER TO REALISE HIGH-DEFINITION ENGRAVINGS, OF QUALITY? AND WITH LESS PRODUCTION TIME, THROUGH THE PURCHASE OF 100 W CLASS I- BIG SMARK 100F EP FIBER MARKING LASER WITH FINE DUST EXTRACTION SYSTEM AND AUTOMATIC PNEUMATIC CLEANING
Gear Fault Location Detection for Split Torque Gearbox Using AE Sensors

In comparison with a traditional planetary gearbox, the split torque gearbox (STG) potentially offers lower weight, increased reliability, and improved efficiency. These benefits have driven helicopter object exchange models (OEMs) to develop products using STG. However, the unique structure of the STG creates a problem on how to locate the gear faults in an STG. As of today, only limited research on STG fault detection using vibration and acoustic emission (AE) sensors has been conducted. In this paper, an effective gear fault location detection methodology using AE sensors for STG is presented. The methodology uses wavelet transform to process AE sensor signals at different locations to determine the arrival time of the AE bursts. By analyzing the arrival time of the AE bursts, the gear fault location can be determined. The parameters of the wavelets are optimized by using an ant colony optimization algorithm. Real seeded gear fault experimental tests on a notional STG are conducted. AE signals at different locations of the gearbox with both healthy and damaged output driving gears are collected simultaneously to determine the location of the damaged gear. Experimental results have shown the effectiveness of the presented methodology.
Forest Fires Effects on Carbon Stocks and Soil Chemistry in Central Yakutia, Eastern Siberia

This study was conducted to determine the impact of fire on the physical and chemical characteristics of soil as well as on the distribution of soil organic and black carbon stocks in ice-rich permafrost regions in eastern Siberia. Three intact and four burnt forest sites with different ignition years were selected. Volumetric water content did not increase in any of the burnt forests in the top soil layer but moisture accumulated at the bottom of the active layer of older burnt sites. Salt content increased in the active layer following forest fires, but a decade later, the salt increase disappeared, indicating the temporal characteristic of this change. The concentration of Na + and SO4 2- in the active layer of the 4-year-old burnt forest site increased 70% and 49% respectively, while other salts (Mg 2+ and Ca 2+ ) did not show any variation in the other burnt forest sites compared to the intact forest sites. The organic carbon stock in the top 200 cm of soil in the intact forest site (44.0 kg m -2 ) was similar to that in burnt forest sites (41.4-43.7 kg m -2 ). On average, 37% of organic carbon was found in the upper 30 cm of the soil profile for intact and burnt forests. The organic carbon distribution in the top 200 cm soil layer in Central Yakutia was higher than previously reported for other Siberian sites. The highest concentrations of black carbon were found in the upper soil layers (20-40 mg g -1 organic carbon) but concentrations of 10-20 mg g -1 organic carbon were also found in the permafrost (120-200 cm depth) of the intact and burnt forests. There was no variation in black carbon concentration among the sites. The presence of black carbon in the permafrost suggests that the active layer was deeper before and that black carbon accumulated because of fires that occurred at that time.
Novel treatment of inflammatory diseases

LipUm has discovered a novel treatment of rheumatoid arthritis (RA) and potentially other inflammatory diseases by a unique
therapeutic antibody directed towards the Bile Salt-Stimulated Lipase, which has been identified as a key target to block and
thereby inhibit the inflammatory process and prevent joint destruction.
The global prevalence of RA is 0.3-1%, and it is twice as common among woman than men, and the risk to develop the
condition increases by age. Frequently, other serious diseases are co-occurring with RA and according to the World Health
Organisation 50% of patients in developed countries are unable to hold a full-time job within ten years after disease onset.
The societal economic burden due to the disease is thus enormous, while health economic calculations estimate the cost for
pharmaceuticals to less than 20% of the total cost. Still, the drug market value growth between 2014 and 2019 is expected to
increase by 55% to 30 billion USD.
The introduction and use of biologicals such as the TNF-alfa inhibitors constituted a major achievement in the treatment, but
with time it has also been concluded that 1/3 of patients are not responding and another 1/3 experience only a transient
improvement. As these biologicals suppress the immune system such drugs should not be combined with other
immunosuppressants, as it may create adverse health effects. Key opinion leaders have therefore pointed out the need for
drugs that have a complementary therapeutic mechanism.
This is the gap that LipUm intends to fill and a tentative strategy is to apply for a orphan drug designation for juvenile
idiopathic arthritis that affect children, frequently with extreme disability and poor quality of life. As an orphan drug our unique
biological more rapidly could contribute to improved treatment of the 85,000 children diagnosed with the disease in Europe.
Renewable Energy Based Smart Irrigation System

Abstract Agriculture is the primary occupation in India and is called India’s backbone. But of late, a lot of problems are being faced in agriculture by the farmers. One of the major problems being water scarcity. As per surveys, almost 20 percent of the agricultural land is wasted due to water scarcity and becomes a barren land. Thus, this research gives an idea of smart irrigation system. This irrigation system uses three sensors namely temperature sensor, humidity sensor and soil moisture sensor, and fuzzy logic is used to operate the solenoid valve. The data from the sensors is then sent to the cloud by using adafruit.io and the farmer can view the moisture level, humidity level and temperature recorded by these sensors. All the operations are governed by an Arduino and the power supply for the Arduino is given by a solar panel which uses LDR (Light Dependent Resistor) and makes it into an automatic tracking system. The crops are grown in two tubs and comparison of growth of plant with automated irrigation and normal irrigation is carried out.