SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
High torque density magnetically-geared switched flux permanent magnet machines

Due to the high price of rare-earth magnets, it is pertinent to develop high torque density permanent magnet (PM) machines with reduced magnet volume, which is the main purpose of this paper. This paper proposes novel high torque density magnetically-geared switched flux permanent magnet machines in which the stator is partitioned into two stators but with armature windings and PM excitations separately on each stator whilst the number of rotor segmented iron pieces is approximately twice or equal to the number of the stator teeth / poles. Therefore, the developed machines are double stator / single rotor machines. The armature outer stator is equipped with concentrated non-overlapping winding and identical to the stator of a fractional-slot PM machine, whilst the structure of the inner excitation stator has interior PMs with flux focusing, but structurally identical to the rotor of a conventional interior PM machine. The influence of design parameters is investigated at a fixed copper loss by a 2-dimensional finite element analysis method. Furthermore, the effect of different rotor and stator pole combinations is also analysed in detail. The electromagnetic performance of the proposed machines show that the odd rotor pole number machines are potentially better in terms of high torque and low torque ripple compared to the equivalent even rotor pole number machines under the same condition, albeit with potential unbalanced magnetic force which may be eliminated by doubling the stator and rotor pole numbers. Finally, the predicted electromagnetic performances of the proposed machines are validated by experiments on the fabricated prototype.
Impact of corporate social responsibility practices on organizational performance: an ISO 26000 perspective

Purpose – This study aims to provide reliable and valid constructs of corporate social responsibility (CSR) and a measurement instrument in the context of Iranian organizations based on the seven core subjects of International Organization for Standardization (ISO) 26000 standard. It also examines the effects of these seven CSR criteria, namely, organizational governance, human rights, labor practices, the environment, fair operating practices, consumer issues and community involvement, and development on the organizational performance of Iranian organizations. Design/methodology/approach – Through an extensive study of literature review, the related items of these core subjects were identified. Data for the study were collected from 207 Iranian manufacturing and service firms. The research model was tested using structural equation modeling. Findings – Statistical analysis revealed that a number of significant relationships between CSR practices and organizational performance of Iranian organizations. The result found that community involvement and development plays an important role in enhancing organizational performance of organizations. Research limitations/implications – First, the time sequence of the association between the variables could not be concluded, given that cross-sectional data were used. A future study is suggested to conduct a longitudinal research design to present the evidence of causation which cannot be achieved through cross-sectional designs. Second, this study was limited to Iran. Hence, the findings and conclusions drawn from this research are representative of the Iranian context only. Hence, final results should be considered with caution. Practical implications – This study offers a number of implications for Iranian managers and policy-makers. First, this study identified that there is a relationship between CSR practices based on the seven core subjects of ISO 26000 and firm performance in the context of Iran. Second, the instrument developed, in this research, will be very useful to policy-makers in various industries of Iran as a tool for evaluating the effectiveness of their current CSR practices and initiatives. Third, decision-makers can also prioritize the CSR practices on which their firms should focus to improve their organizational performance. Originality/value – The novelty of this research is to determine the related items of the core subjects of ISO 26000 as the main factors and offer an instrument to measure the effects of various CSR practices on organizational performance of Iranian firms in the context of Iran.
Crosstalk between nuclear envelope and dna damage response: role of nucleoporin tpr in the maintenance of genomic integrity

Each cell in the human body receives thousands of DNA lesions per day. To counteract threats posed by DNA damage, cells have evolved an integrated signaling network called the DNA-damage response (DDR). This mechanism allows cells to detect DNA lesions, signal their presence and promote their repair. Mutation of DDR genes, which serves as a biological barrier against tumor progression, leads to cancer development2. A large-scale proteomic analysis of proteins phosphorylated in response to DNA damage by checkpoint kinases ATM and ATR identified extensive protein networks responsive to DNA damage. Interestingly, among the proteins identified to be phosphorylated upon DNA damage were several nuclear pore complex factors including nucleoporin Translocated Promoter Region (TPR)5. TPR was previously linked to cancer since its N-terminal domain has been found fused with the protein kinase domains of various proto-oncogenes such as RAF and MET resulting in human solid tumors. TPR expression level was found deregulated in many types of human tumors such as breast and liver cancer8. Amplification of TPR was also significantly associated with a shorter survival of patients with pediatric intracranial ependymomas9. All these findings support a critical role for TPR in the mechanism of oncogenesis. By employing state-of-the-art proteomics (SILAC), genetics (in vitro mutagenesis), genomics (DNA binding profiling) and imaging (electron microscopy) technologies we will investigate how TPR prevents tumor genesis via its role in the DDR network coordinating DNA repair, DNA replication and chromatin condensation with the nuclear envelope upon DNA damage. Providing mechanistic insight into the role of TPR in DDR and the maintenance of genome stability will not only contribute to our understanding of molecular principles of response to damaged DNA, but will allow us to optimize existing cancer treatments and design new molecular targeted therapies in the future.
Care study: a cardiovascular physical assessment

Patient assessment has always been an integral part of the nursing process. However, the physical aspects of a nursing assessment has been traditionally limited to the recording and interpretation of vital signs, whilst systematic physical assessments has been part of the doctor's role (West, 2006). As nurses are now expanding their roles into areas of advanced practice and prescribing, they need to be able to provide effective holistic care and respond to changes in their patient’ status. This care study will describe a framework for conducting a comprehensive cardiovascular assessment which will include history taking and a particular focus of the physical assessment skills of inspection, palpation, percussion and auscultation.
Multi –Mode Biometric Solution for Examination Malpractices in Nigerian Schools

The major technique for admitting students to an examination over the years has been through the presentation of a token. The student possesses a physical and portable device which contains the user identity. Examples of such devices include ID cards, Library Cards, Fees Clearance Cards, Photo Cards, etc. However, this method of authenticating a student for an examination has an obvious problem. The problem is that object can be misplaced, stolen, forgotten at home or somewhere, and ID card can also be faked. This paper presents a multi-mode biometrics (fingerprint and face) solution to the problem of examination malpractice in Nigerian schools. The appearance of both fingerprint scanner and web cam on modern laptop and notebook computers motivate the writing of this paper.
Towards a political ecology of the digital economy: Socio-environmental implications of two competing value models

Abstract This article explores the socio-environmental implications of two different value models currently competing for dominance in the digital economy: the neo-feudal cognitive capitalism (NFCC) and the hypothetical case of mature peer production (HMPP). Using a systematisation that considers environmental effects of information and communication technologies as direct, indirect and structural, this article discerns the future socio-environmental scenarios indicative of each value model. We argue that the two value models share the same type of direct environmental effects associated with a similar technological infrastructure; however, their indirect effects differ in prospects of consumer behaviour, environmental awareness and product design. Likewise the difference in structural effects is significant as the NFCC is based on profit maximisation and an accumulation of capital, whereas the HMPP is agnostic to growth and oriented towards the commons. Hence, the latter is considered as the socio-environmentally auspicious choice, but comes not without transitional challenges of its own.
What’s the Frequency, Kenneth?: Sublinear Fourier Sampling Off the Grid

We design a sublinear Fourier sampling algorithm for a case of sparse off-grid frequency recovery. These are signals with the form $$f(t) = \sum _{j=1}^k a_j \mathrm{e}^{i\omega _j t} + \int \nu (\omega )\mathrm{e}^{i\omega t}d\mu (\omega )$$f(t)=?j=1kajei?jt+??(?)ei?tdμ(?); i.e., exponential polynomials with a noise term. The frequencies $$\{\omega _j\}$${?j} satisfy $$\omega _j\in [\eta ,2\pi -\eta ]$$?j?[?,2?-?] and $$\min _{i\ne j} |\omega _i-\omega _j|\ge \eta $$mini?j|?i-?j|?? for some $$\eta > 0$$?>0. We design a sublinear time randomized algorithm which, for any $$\epsilon \in (0,\eta /k]$$∈?(0,?/k], which takes $$O(k\log k\log (1/\epsilon )(\log k+\log (\Vert a\Vert _1/\Vert \nu \Vert _1))$$O(klogklog(1/∈)(logk+log(?a?1/???1)) samples of $$f(t)$$f(t) and runs in time proportional to number of samples, recovering $$\omega _j'\approx \omega _j$$?j???j and $$a_j'\approx a_j$$aj??aj such that, with probability $$\varOmega (1)$$Ω(1), the approximation error satisfies $$|\omega _j'-\omega _j|\le \epsilon $$|?j?-?j|≤∈ and $$|a_j-a_j'|\le \Vert \nu \Vert _1/k$$|aj-aj?|≤???1/k for all $$j$$j with $$|a_j|\ge \Vert \nu \Vert _1/k$$|aj|????1/k. We apply our model and algorithm to bearing estimation or source localization and discuss their implications for receiver array processing.
Astrophysics for the dark universe: cosmological simulations in the context of dark matter and dark energy research

The objective of this ambitious research proposal is to push forward the frontier of computational cosmology by significantly improving the precision of numerical models on par with the increasing richness and depth of surveys that aim to shed light on the nature of dark matter and dark energy.

Using new phase-space techniques for the simulation and analysis of dark matter, completely new insights into its dynamics are possible. They allow, for the first time, the accurate simulation of dark matter cosmologies with suppressed small-scale power without artificial fragmentation. Using such techniques, I will establish highly accurate predictions for the properties of dark matter and baryons on small scales and investigate the formation of the first galaxies in non-CDM cosmologies.
Baryonic effects on cosmological observables are a severe limiting factor in interpreting cosmological measurements. I will investigate their impact by identifying the relevant astrophysical processes in relation to the multi-wavelength properties of galaxy clusters and the galaxies they host. This will be enabled by a statistical set of zoom simulations where it is possible to study how these properties correlate with one another, with the assembly history, and how we can derive better models for unresolved baryonic processes in cosmological simulations and thus, ultimately, how we can improve the power of cosmological surveys.
Finally, I will develop a completely unified framework for precision cosmological initial conditions (ICs) that is scalable to both the largest simulations and the highest resolution zoom simulations. Bringing ICs into the ‘cloud’ will enable new statistical studies using zoom simulations and increase the reproducibility of simulations within the community.

My previous work in developing most of the underlying techniques puts me in an excellent position to lead a research group that is able to successfully approach such a wide-ranging and ambitious project.
Saastal Valle Anzasca Bike

The project provides an answer to the tourist vocation of the area by promoting a sustainable enhancement of the environmental heritage. It has specific objectives: the development and promotion of the tourism potential linked to the cycle-hiking in the cross-border area surrounding Monte Rosa; the completion of a route for mountain bikes and e-bikes that connects the Saas Valley with the Anzasca Valley without interruptions, the integrated and shared enhancement of a territory characterized by a common environmental and cultural context (the area of Monte Rosa, Walser). Arrival and departure of the route will be connected to the most important roads and railways. It is estimated that the project will affect the increase and diversification of the number of tourists and the competitiveness of the economic activities present in the territory of the two valleys.
Innovative combination therapy against bladder cancer

The objective of this project is to lay foundation for the continued clinical development and commercialisation of MFA-370, a novel medication against Bladder Cancer (BC).
BC is the ninth most common cancer worldwide. In Europe, more than 175,000 people are diagnosed with BC in Europe each year, and this number is increasing, especially among women. Compared to other major cancer types, the relative five-year survival rate in BC has remained unchanged for the past 20 years. The implications are clear: the development of new therapies targeting BC is thus warranted and in great demand among clinicians and BC patients. The established treatments are highly aggressive, leading to major side-effects and reduction in QoL among patients. 
Recognizing large unmet clinical need, Ectin has developed a novel combination BC therapy consisting of a well-defined ratio of two commonly utilized pharmaceuticals with expired patents. In the pre-clinical studies, MFA-370 has shown to be able to induce cancer cell death without the addition of any chemotherapeutic or radiotherapeutic agent. This offers a new hope to BC patients. The pre-clinical evaluation of this medication is completed, enabling continued development process.
In the Phase 1 project, we will develop a business plan that will guide the future clinical studies and exploitation efforts (to be pursued in the Phase 2 project). The assumed commercialisation strategy is to take the product to the Phase I/IIa level and thereafter acquire strategic partner for continued clinical studies and market launch.
Fighting BC is an EU-wide challenge, as it is one of the most expensive malignancies to treat and affects all genders and age groups. At the same time, research targeting the disease is greatly underfunded in the EU and internationally. MFA-370 delivers in this context a strong EU-added value by its potential to induce tumour necrosis in BC and being based on well-documented compounds that are cost-efficient to manufacture.
Co2 human emissions

The CO2 Human Emissions (CHE) project will coordinate efforts towards developing a European monitoring capacity for anthropogenic CO2 emissions. This challenging target is aligned with the European Commission’s stepwise approach for a requirement-driven integration of Earth observations, from remote sensing and in situ, with enhanced modelling capabilities for CO2 fossil fuel emissions, along with other natural and anthropogenic CO2 emissions and transport. The project will pursue a consolidated methodology for integrating the monitoring system components, as well as innovation for estimating fossil fuel CO2 fluxes. These include reconciling bottom-up and top-down constraints and handling systematic errors of satellite sensors. Earth observations from satellites will be combined with in situ CO2 observations and information from co-emitters or isotopes to support the attribution of fossil fuel emissions and uncertainty reduction. Methodological advances will include a representation of anthropogenic CO2 variability in space and time, responding to documented shortcomings and needs, and a carbon cycle data assimilation system extended to enable estimates of emission uncertainties. Strategies to separate anthropogenic CO2 emissions from biogenic fluxes at country to global scales using observations and models will be documented. CHE will support a large community by providing a library of realistic CO2 simulations from global to city scale to examine the capacity for monitoring future fossil fuel emissions and to adequately dimension space mission requirements. Community building will include direct collaboration across 22 European institutions, and communication and liaison with key European and international stakeholders. These coordination efforts will ensure the transfer of science and technology requirements and recommendations for strengthening existing assets with a view to developing an anthropogenic CO2 monitoring service.
New converter circuitry for high v applications using Switched Inductor Multilevel Converter

This paper presents an analysis and design of a high voltage gain DC-DC converter. This converter is a single stage DC-DC multilevel boost converter topology with very large voltage gain conversion ratio. It is called a Switched Inductor Multilevel Boost Converter (SIMLBC). It converts a low voltage level to high voltage level to be used in any application that requires high voltages. The capacitors in the output circuit provide a different output dc levels suitable for multilevel inverter applications. The main problem of any multilevel converter is the efficiency because there are a lot of components that consume power. So this work investigates practical circuit analysis. The non-ideal voltage gain of the new topology and their efficiency of the system are derived. The equivalent series resistance (ESR) of the capacitors, dc winding resistance (DCR) of the two inductors, the forward voltage of the diodes, and the drain-source resistance of the switch have been taken into consideration. The calculated efficiency of the system is compared to the simulation one to validate the analyses. Mathcad software is used to compare the simulation with the calculation and experimental results. Results provide the guidelines for an accurate and efficient design.
Quality of Service (QoS) Provisions in Wireless Sensor Networks and Related Challenges

Wireless sensor networks (WSNs) are required to provide different levels of Quality of Services (QoS) based on the type of applications. Providing QoS support in wireless sensor networks is an emerging area of research. Due to resource constraints like processing power, memory, bandwidth and power sources in sensor networks, QoS support in WSNs is a challenging task. In this paper, we discuss the QoS requirements in WSNs and present a survey of some of the QoS aware routing techniques in WSNs. We also explore the middleware approaches for QoS support in WSNs and finally, highlight some open issues and future direction of research for providing QoS in WSNs.
Improvement of biocontrol efficacy of Trichoderma harzianum vs. Fusarium oxysporum f. sp. lycopersici through UV-induced tolerance to fusaric acid

Abstract Competition is one of the potential mechanisms of the antagonistic action of Trichoderma harzianum against Fusarium oxysporum. The competitive capability of the T. harzianum isolate ITEM 908 (Th908) vs. an isolate of F. oxysporum f. sp. lycopersici was improved via enhancement of the tolerance to growth-inhibitory metabolites produced by F. oxysporum. HPTLC and HPLC analyses led to the identification of fusaric acid (FA) as the major metabolite in culture filtrate of the phytopathogenic F. oxysporum strain ITEM 2797 (Fo2797). FA, a phytotoxin which has also been reported to be released in soil, totally inhibited the growth of Th908 on PDA containing 120 μg of FA per gram in 3-day trials. Through UV-C irradiation and subsequent selection of mutants able to grow on PDA supplemented with culture extracts of Fo2797 or FA, one stable tolerant mutant (Th908-5) with unaltered physiological features and rhizosphere competence was isolated. The biocontrol capability of the UV-mutant Th908-5 was compared to that of the wild-type strain Th908 on tomato plants grown in a substrate heavily infested with Fo2797 in two separate trials. The reduction of the disease by Th908-5 was highly (P
Force nanoscopy of staphylococcal biofilms

Staphylococcus aureus is a leading cause of hospital-acquired infections, which are often complicated by the ability of this pathogen to grow as biofilms on indwelling medical devices. Because biofilms protect the bacteria from host defenses and are resistant to many antibiotics, biofilm-related infections are difficult to fight and represent a tremendous burden on our healthcare system. Today, a true molecular understanding of the fundamental interactions driving staphylococcal adhesion and biofilm formation is lacking owing to the lack of high-resolution probing techniques. This knowledge would greatly contribute to the development of novel anti-adhesion therapies for combating biofilm infections.

We recently established advanced atomic force microscopy (AFM) techniques for analyzing the nanoscale surface architecture and interactions of microbial cells, allowing us to elucidate key cellular functions. This multidisciplinary project aims at developing an innovative AFM-based force nanoscopy platform in biofilm research, enabling us to understand the molecular mechanisms of S. aureus adhesion in a way that was not possible before, and to optimize the use of anti-adhesion compounds capable to inhibit biofilm formation by this pathogen.

NanoStaph will have strong scientific, societal and economical impacts. From the technical perspective, force nanoscopy will represent an unconventional methodology for the high throughput and high resolution characterization of adhesion forces in living cells, especially in bacterial pathogens. In microbiology, the results will radically transform our perception of the molecular bases of biofilm formation by S. aureus. In medicine, the project will provide a new screening method for the fast, label-free analysis of anti-adhesion compounds targeting S. aureus strains, including antibiotic-resistant clinical isolates that are notoriously difficult to treat, thus paving the way to the development of anti-adhesion therapies.
Main Factors Controlling Oil-Gas Enrichment Regularities and Accumulation Modes of Putaohua Oil Layer in Chaochang Region

In order to clarify some kinds of geological conditions on the hydrocarbon accumulation process, this paper analyses the main factors controlling oil-gas enrichment regularities of Putaohua oil layer in Chaochang region of Daqing city, which conclude tectonics, sedimentary characteristics, oil source condition and the mutual relationship between of them. The results show that the organic abundance of hydrocarbon source rocks of Qing1 section control oil and gas distribution range. The configuring relationships of oil-source fault and reservoir sand body control oil and gas migration. The configuring relationship of sedimentary micro-facies types and structures controls oil and gas distribution. On the basis of these studies, oil and gas accumulation mode in Putaohua reservoir are summarized in Chaochang region. There are two accumulation models: nearby accumulation mode in northwest and updip accumulation mode in southeast.