SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
SUSTAINABLE MEASURES FOR ACHIEVING RESILIENT TRANSPORTATION IN METROPOLITAN REGIONS

Transportation in urban areas, particularly metropolitan regions, generates congestion and vast greenhouse gas emissions and thus imposes enormous challenges upon authorities in providing healthy living conditions for inhabitants and a supportive environment for businesses. Thus, the overall objective of the SMART-MR is to support local and regional authorities in improving transport policies and providing sustainable measures for achieving resilient low-carbon transportation and mobility in metropolitan regions. To tackle this issue, 10 project partners from 8 metropolitan regions (Oslo, Göteborg, Helsinki, Budapest, Ljubljana, Rome, Porto and Barcelona) will share their experience in transport and mobility planning by organizing 7 topically interrelated workshops. For each workshop the partners will issue an in-depth analysis, describe good practices and organise a study visit. Practical experience will be presented and discussed, and policy recommendations developed. Through the project outputs, such as the guide on sustainable measures for achieving resilient transportation in metropolitan regions, selected good practice descriptions, and policy recommendations, and through dissemination events, such as political meetings, the final conference, and regional stakeholder meetings, SMART-MR contributes to Europe 2020 goals, Cohesion Policy, and the Interreg Europe Program by aiding managing authorities and regional and local authorities in setting new transport and mobility policies. In particular, metropolitan regions will prepare and implement action plans to improve the implementation of transport policies and the respective 8 policy instruments by:
- provision of integrated transport or sustainable urban mobility plans;
- deploying low-carbon urban transit-oriented development in the form of intermodal nodes and urban station communities; and
- including stakeholders in project activities and in the design and implementation of the action plans.
ITINERAS

ITINERAS aims at making more attractive the territory to tourists, in Saint-Gervais-les-Bains in Haute-Savoie and Valgrisenche in Valle d’Aosta, by enhancing the cultural heritage with the help of the local population to guarantee the sustainability of the investments and works made. The project ITINERAS intends to make important investments to safeguard the sacred architectural heritage of both towns. In addition, these investments will be coupled with a promotional operation of sustainable tourism based on the direct involvement of the local population.
La costellazione del ‘new Italian weird’ tra letteratura estrema e ipermodernità

Il contributo ricostruisce la costellazione della narrativa italiana contemporanea più ‘strana’, soprannominata ‘new Italian weird’ nel dibattito on line che ha accompagnato il fenomeno editoriale tra il 2016 e il 2018, e la raffronta con i suoi corrispettivi negli Stati Uniti e in Europa per ragionare su come e perché i sistemi letterari si trasformano nel tempo. Una lettura semiologica e polisistemica ha permesso di ricondurre le modalità di questo recente sentire letterario a una più ampia condizione della contemporaneità, il cui carattere esasperato è stato definito anche in termini di ipermodernità e che oggi sembrerebbe implicare una sempre maggiore ibridazione tra i generi del romanzo. A caratterizzare questa nuova forma di letteratura, a suo modo estrema, è il ricorso al ‘weird’, qui inteso non come genere a sé ma come dispositivo ‘obliquo’, impiegato per aprire nuove prospettive e per oltrepassare gli stretti confini e le limitate possibilità di senso del reale.
A Robust Finite Element Analysis of the Rail-Wheel Rolling Contact

Appraisal of contact stresses, surface cracks, and plastic deformations in rails and wheels has always been an important issue in mechanical and railway engineering because of two main reasons. In the first place, these inappropriate events lead to the reduction of service life of the railway track. Besides, studying railway systems requires both time-consuming analysis methods and expensive experimental works. In this paper, a railway system containing wheel, rail, axle, and pads is modeled and analyzed. Using elastic-plastic materials, mapped meshing, and the rolling motion of the wheel contingent upon the up-to-date international railway systems results in high accuracy in the solutions of this problem. ANSYS software is utilized with the purpose of simulating the system. The contribution of this study is on the basic way of managing Rail-Wheel interaction problems from a finite element method point of view. So, stress distribution, elastic and plastic strains as well as nodal forces are considered, simultaneously. The results obtained from the simulation have suitable agreement with the real life experiences. Another feature of this paper is that it demonstrates essential steps for more realistic 3D solutions to the aforementioned problems.
SUPPORT MODULE FOR LITHOGRAPHY SYSTEM

The invention relates to a support structure and support module, for instance for use in a lithography system, comprising a frame and a support for supporting a load, wherein said support is moveable relative to said frame, said support structure further comprising a force compensation spring assembly connecting said support to said frame for at least partially supporting said support and/or said load, wherein said force compensation spring assembly comprises a first spring having a negative stiffness characteristic over a predefined range of motion of said spring, and a second spring having a positive stiffness.
Abstract P097: Maternal Vascular Changes during Pregnancy may Persist Postpartum

Introduction: Higher parity (number of births) is associated with increased subclinical cardiovascular disease (CVD) in mid-life and older women, and with increased risk of CVD overall. In the only study of reproductive age women, common carotid artery intima-media thickness (CCA IMT) was greater after each birth. Prospective studies of arterial change throughout normal pregnancy are lacking; without them it is unclear whether unhealthy changes of the vasculature during pregnancy persist postpartum and raise women’s risk of CVD. The goal of this study was to prospectively assess normal vascular adaptation in healthy pregnant women. Hypotheses: During the course of healthy pregnancy: 1. CCA adventitial diameter (AD) will increase, then return to baseline postpartum, 2. CCA IMT will initially thin, then thicken as pregnancy progresses, then return to baseline postpartum, and 3. brachial artery distensibility will not change. Methods: We assessed 43 healthy women during each trimester of their first pregnancy and 6-8 weeks postpartum with B-mode ultrasound imaging of the CCA IMT and AD, independent predictors of CVD risk. Brachial artery distensibility, representing elasticity of the artery, was measured using the DynaPulse wave form analyzer. Linear mixed models were used to compare measures of CCA IMT, adventitial diameter, and brachial artery distensibility at each time point, after adjustment for age and pre-pregnancy BMI. Results: There were 37 women (age 28.2 ± 4.5 years, pre-pregnant BMI 24.4 ± 3.2 kg/m 2 ) with uncomplicated pregnancies. Six women with pregnancy complications were excluded from these analyses. After adjustment for age and pre-pregnancy BMI, mean (SE) CCA AD (mm) increased each trimester, from 6.38(0.08) in the 1 st trimester to 6.92(0.09) in the 3 rd trimester, and returned to baseline, 6.35 (0.07), postpartum. Pairwise comparisons were all statistically significant at p&lt;.01. Mean (SE)CCA IMT (mm) was increased postpartum (0.567 (0.01)) compared to 1 st (0.539 (0.01)) and 2 nd trimester values (0.546 (0.01), p &lt; .05 for each). Mean (SE) brachial artery distensibility (%/mmHg) decreased from 7.64 (0.28) 1st trimester to 6.84 (0.21) 3rd trimester (p &lt; .01) and then remained unchanged at 6.82 (0.21) postpartum. Conclusions: As we hypothesized, in uncomplicated first pregnancies CCA AD increased throughout and returned to baseline postpartum. However, contrary to our hypotheses, CCA IMT increased postpartum, and the brachial artery stiffened during pregnancy and remained stiffer 6-8 weeks postpartum. In uncomplicated first pregnancies, some vascular changes resolved (CCA AD) and others persisted (CCA IMT and brachial artery stiffness). Whether this indicates that persistence of specific vascular effects of pregnancy may inform long term CVD risk remains to be explored.
Amelogenin Processing by MMP-20 Prevents Protein Occlusion Inside Calcite Crystals

Calcite crystals were grown in the presence of full-length amelogenin and during its proteolysis by recombinant human matrix metalloproteinase 20 (rhMMP-20). Recombinant porcine amelogenin (rP172) altered the shape of calcite crystals by inhibiting the growth of steps on the {104} faces and became occluded inside the crystals. Upon co-addition of rhMMP-20, the majority of the protein was digested resulting in a truncated amelogenin lacking the C-terminal segment. In rP172-rhMMP-20 samples, the occlusion of amelogenin into the calcite crystals was drastically decreased. Truncated amelogenin (rP147) and the 25-residue C-terminal domain produced crystals with regular shape and less occluded organic material. Removal of the C-terminal diminished the affinity of amelogenin to the crystals and therefore prevented occlusion. We hypothesize that HAP and calcite interact with amelogenin in a similar manner. In the case of each material, full-length amelogenin binds most strongly, truncated amelogenin binds weakly and the C-terminus alone has the weakest interaction. Regarding enamel crystal growth, the prevention of occlusion into maturing enamel crystals might be a major benefit resulting from the selective cleavage of amelogenin at the C-terminus by MMP-20. Our data have important implications for understanding the hypomineralized enamel phenotype in cases of amelogenesis imperfecta resulting from MMP-20 mutations and will contribute to the design of enamel inspired biomaterials.
A grand unified theory of decidability in logic-based knowledge representation

Logic-based knowledge representation (KR) constitutes a vital area of IT. The field  inspires and guides scientific and technological developments enabling intelligent management of large and complex knowledge resources. Elaborate languages for specifying knowledge (so-called ontology languages) and querying it have been defined and standardized. Algorithms for automated reasoning and intelligent querying over knowledge resources are being developed, implemented and practically deployed on a wide scale. 
Thereby, decidability investigations play a pivotal role to characterize what reasoning or querying tasks are at all computationally solvable. 
Past decades have seen a proliferation of new decidable formalisms for KR, dominated by two major paradigms: description logics and rule-based approaches, most notably existential rules. Recently, these research lines have started to converge and first progress has been made toward identifying commonalities among the various formalisms. Still, the underlying principles for establishing their decidability remain disparate, ranging from proof-theoretic notions to model-theoretic ones. 
DeciGUT will accomplish a major breakthrough in the field by establishing a ""Grand Unified Theory"" of decidability. We will provide a novel, powerful model-theoretic criterion inspired by advanced graph-theoretic notions. We will prove that the criterion indeed ensures decidability and that it subsumes most of (if not all) currently known decidable formalisms in the KR field.
We will exploit our results toward the definition of novel decidable KR languages of unprecedented expressivity. We will ultimately extend our framework to encompass more advanced KR features beyond standard first order logic such as counting and non-monotonic aspects.
Our research will draw from and significantly impact the scientific fields of AI, Database Theory and Logic, but also give rise to drastically improved practical information management technology.
Efficacy and safety of Brucea javanica oil emulsion for liver cancer

Brucea javanica oil emulsion (BJOE), extracted from the Chinese herb Bruceae Fructus (Yadanzi), is a broad-spectrum anti-tumor drug and has been widely used for the treatment of liver cancer in China. The aim of this study is to systematically investigate the efficacy and safety of BJOE for the treatment of liver cancer.Seven electronic databases including the Cochrane Library, PubMed, Excerpt Medica Database, Chinese Biomedical Literature Database, China National Knowledge Infrastructure, China Scientific Journal Database, and Wanfang Database will be systematically retrieved for data extraction from their inceptions to September 2020. Cochrane Risk of Bias tool will be used to assess the risk of bias of included studies. The RevMan 5.4 and Stata 16.0 software will be applied for statistical analyses. Statistical heterogeneity will be computed by I tests. Sensitivity analysis will be conducted to evaluate the stability of the results. The publication bias will be evaluated by funnel plots and Egger test. The quality of evidence will be assessed by the GRADE system.The results of our research will be published in a peer-reviewed journal or presenting the findings at a relevant conference.The conclusion of this study will provide helpful evidence of the effect and safety of BJOE for the treatment of liver cancer in clinical practice.10.17605/OSF.IO/UC8XQ.
LA PRODUCCIÓN LECHERA DESDE LA PERIFERIA. LA CUENCA LÁCTEA DE FRAY MAMERTO ESQUIU, CATAMARCA

Este artículo propone una reflexión respecto de la relevancia que adquiere la producción lechera bovina en Fray Mamerto Esquiú, un espacio geográfico considerado periférico para la producción láctea si se tienen en cuenta indicadores productivos como la cantidad de litros producidos, la cantidad de animales en producción, la superficie ocupada, etc. (Gutman et al., 2003; Sánchez et. al., 2012). Llevamos adelante un estudio centrado en caracterizar los actores del territorio, describiendo las particularidades de las unidades productivas y su relación con las organizaciones y las instituciones que promovieron su desarrollo (Fernandes, 2006, 2009), incorporando la dimensión histórica al análisis de la situación actual. Metodológicamente, llevamos adelante un estudio cualitativo que alcanzó a la totalidad de unidades productivas.
Practical probabilistic programming with monads

The machine learning community has recently shown a lot of interest in practical probabilistic programming systems that target the problem of Bayesian inference. Such systems come in different forms, but they all express probabilistic models as computational processes using syntax resembling programming languages. In the functional programming community monads are known to offer a convenient and elegant abstraction for programming with probability distributions, but their use is often limited to very simple inference problems. We show that it is possible to use the monad abstraction to construct probabilistic models for machine learning, while still offering good performance of inference in challenging models. We use a GADT as an underlying representation of a probability distribution and apply Sequential Monte Carlo-based methods to achieve efficient inference. We define a formal semantics via measure theory. We demonstrate a clean and elegant implementation that achieves performance comparable with Anglican, a state-of-the-art probabilistic programming system.
Zeneo® adrenaline needle-free adrenaline pre-filled autoinjector rescues you from an anaphylactic shock

Anaphylactic shock is a serious, life-threatening allergic reaction in which the airways suddenly close; if not properly treated it causes death in 20 minutes. Seventeen million Europeans suffer from food allergies, 3.5 million which are children or young adults. Across Europe, food allergy is the leading cause of anaphylaxis in children aged 0-14 years and there is a huge increase in hospitalizations for allergic reactions in children in the last 10 years. Anaphylaxis sends someone to the emergency room every 3 minutes. The only way to counteract an anaphylactic shock is to inject adrenaline to guarantee enough oxygen to the heart. The adrenaline market is estimated to create revenues of €1.2 billion worldwide, and there is only one big player that produce prefilled syringes.
Crossject already has the know-how to produce pre-filled needle free autoinjectors, our ZENEO® line. We already have 4 ZENEO® products so we are the right company to enter the adrenaline market with a cutting-edge solution.
ZENEO® Adrenaline is an innovative, needle-free, easy-to-use auto-injector suitable for emergency situations, that enables patients and relatives to administer adrenaline. It performs a quick injection (1/10 of a second) avoiding the needle-related discomfort and the risk of contamination, moreover it guarantees intramuscular injection. The end-users of our product are people that are having an anaphylactic shock. People with food allergies are those that will need our device the most as they are more prone to anaphylaxis, however an anaphylactic shock can happen to anyone.
We plan to launch ZENEO® Adrenaline on the market in Q4 2021. We will a turnover of €136M and a profit of €124M by the fifth year of commercialization. We expect to achieve the payback between the second and the third year of commercialization and to generate ROI of 3.36 by the fifth year of commercialization. Moreover, we estimate to create a total of 28 new jobs during these 5 years.
Predictive in vitro diagnostics test for individualized tailoring of chemotherapy in primary breast cancer

SIVIDON established a prototype diagnostic assay - the ChemoPredict test - to stratify high-risk breast cancer patients and to help in deciding whether to treat the patient with standard anthracycline-based chemotherapy without taxane or taxane-containing regimens. ChemoPredict was clinically validated in a large clinical phase III trial (FinHer) with 919 patients using a prospective-retrospective approach. The existing training and validation studies of ChemoPredict provided evidence that the assay can reduce the number of taxane-based chemotherapies within the test’s target group by about 50% without impairment of outcome of the patients. Thus, the use of the assay in breast cancer care will result in a more specific use of taxanes and a reduction of overtreatment thus avoiding serious side effects in patients and saving costs for the health care system.
SIVIDON’s aim for the overall innovation project is to extend clinical and analytical validation data, to develop ChemoPredict as a CE-marked IVD test according to IVD directive 98/79/EC and to bring this test as a tool for personalized medicine into the European market.
The objective of the feasibility study is to generate an elaborated business plan including detailed market analyses for ChemoPredict. Several key opinion leaders will be interviewed to get their perspective on the application, the inclusion into clinical guidelines and market entrance of the innovative predictive test. Phase I will be also used to decide on an extended clinical validation strategy to ensure that the ChemoPredict assay exhibits the highest clinical evidence level. Advisory boards will be initiated, opportunities for entering clinical guidelines will be judged and reimbursement concepts in European countries will be assessed. Regulatory issues will be comprehensively evaluated to decide on the best product development strategy, a detailed product development plan will be generated and phase 0 development strategies will be started.
Dante: digital alarm network and tracking equipment for forest fire detection

Wildfires are a global phenomenon which can have a devastating impact on a country’s population, economy and environment. Although fire suppression costs are increasing every year, there is still a constant increment in the frequency and severity of wildfires. According to EM-DAT, 5.8 million people are affected worldwide every year by wildfires, with estimated economic costs of 45,000 million Euros. 

DANTE is the integrated low-cost solution for the early detection of wildfires that has received the awards Copernicus Masters 2017 and ESNC 2017. These are international competitions established on the initiative of ESA, GSA and the Copernicus Programme in which DANTE was rated as a business innovation to address EU challenges and an investment opportunity. DANTE is a prompt alarm system which features advanced methods to report and manage a fire within seconds of its starting. It provides the exact geo-referred coordinates of the fire source, tracks accurately the fire as it evolves and guides the firefighting extinguishing operations as a real-time navigator. The system is compatible with existing emergency control rooms and is managed remotely from either the control room or a smartphone with internet connectivity. DANTE has the potential to halve the yearly budget of public and private entities dedicated to wildfires extinction and detection (estimated to be of 10,600 million Euros extrapolating EM-DAT database).

DANTE will be commercialised directly by AD TELECOM, including a network of official distributors to maximise the sales worldwide. This project will enhance the ambition of the company to grow and internationalise, targeting an inter-sectorial market in a B2B and B2B2B business model. First sales are expected in 2019, and the annual turnover is calculated to stay permanently above a million Euros after 2020. The company targets a total sale of 150,000 units within a lifetime of 12 years, which translates to a global turnover of 126 million Euros.
Implementação de tecnologia inovadora de produção de junta rotativa inovadora usando centro de torneamento CNC, Śrem

Projeto de compra em 2019: Centro de torneamento CNC — 1 pc. e absorvedor de névoa de óleo — 1 pc. (total 1 WF), que é necessário para o início da produção da articulação rotativa patenteada em 2014 para a liberação precisa e rápida das folgas nas partes colaborantes e seu alinhamento. Como resultado do projeto, um novo produto será introduzido em 2020 — uma junta rotativa usada em escavadoras e carregadoras (por exemplo, Atlas Copco e Caterpillar), bem como em guindastes de construção, cabeças de ponte, mineração e indústrias aeroespaciais. É um tipo de conector rotativo usado para conectar peças rotativas de máquinas e dispositivos com linhas de alimentação de mídia fixa, cumprindo o papel de um selo rotativo. Sua rigidez e capacidade de suporte de carga adequadas são de particular importância, pois é uma combinação que permite a rotação livre no nó. Para que a articulação funcione corretamente, as superfícies cónicas devem respeitar-se firmemente entre si e ter uma rugosidade baixa (Rá=0,80 µm no máximo) e a tolerância do ângulo do cone não deve ser superior a 10" (minuto), a tolerância das dimensões lineares lt; 0.005 a 0,008 mm. Outros produtos em 2019: 1 pres. receber apoio, 1 pres. receber uma subvenção, valor de 693.900 investimento. apoio público total para pres. (subvenções), 1 pres. vol. a fim de introduzir uma nova pr. no mercado e nova para a empresa.A implementação do projeto permitirá a introdução em 2020: 1 inovação de produto — junta rotativa utilizada em máquinas de condução/aeronaves, 1 processo — ferramentas de torneamento com lâminas de nitreto de boro que servem em um único trabalho de torneamento, perfuração, fresagem e 1 não-tecnologia. (org.) — controle total do processo de usinagem, controle on-line. Graças a isso, o processo de processamento de elementos individuais é fechado em um único ciclo, que é ideal para obter a precisão especificada nos mícrones e rugosidade adequada do material, impossível de obter na produção tradicional.