SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Cryptic variation in an ecological indicator organism: mitochondrial and nuclear DNA sequence data confirm distinct lineages of Baetis harrisoni Barnard (Ephemeroptera: Baetidae) in southern Africa

Baetis harrisoni Barnard is a mayfly frequently encountered in river studies across Africa, but the external morphological features used for identifying nymphs have been observed to vary subtly between different geographic locations. It has been associated with a wide range of ecological conditions, including pH extremes of pH 2.9-10.0 in polluted waters. We present a molecular study of the genetic variation within B. harrisoni across 21 rivers in its distribution range in southern Africa.Four gene regions were examined, two mitochondrial (cytochrome c oxidase subunit I [COI] and small subunit ribosomal 16S rDNA [16S]) and two nuclear (elongation factor 1 alpha [EF1α] and phosphoenolpyruvate carboxykinase [PEPCK]). Bayesian and parsimony approaches to phylogeny reconstruction resulted in five well-supported major lineages, which were confirmed using a general mixed Yule-coalescent (GMYC) model. Results from the EF1α gene were significantly incongruent with both mitochondrial and nuclear (PEPCK) results, possibly due to incomplete lineage sorting of the EF1α gene. Mean between-clade distance estimated using the COI and PEPCK data was found to be an order of magnitude greater than the within-clade distance and comparable to that previously reported for other recognised Baetis species. Analysis of the Isolation by Distance (IBD) between all samples showed a small but significant effect of IBD. Within each lineage the contribution of IBD was minimal. Tentative dating analyses using an uncorrelated log-normal relaxed clock and two published estimates of COI mutation rates suggest that diversification within the group occurred throughout the Pliocene and mid-Miocene (~2.4-11.5 mya).The distinct lineages of B. harrisoni correspond to categorical environmental variation, with two lineages comprising samples from streams that flow through acidic Table Mountain Sandstone and three lineages with samples from neutral-to-alkaline streams found within eastern South Africa, Malawi and Zambia. The results of this study suggest that B. harrisoni as it is currently recognised is not a single species with a wide geographic range and pH-tolerance, but may comprise up to five species under the phylogenetic species concept, each with limited pH-tolerances, and that the B. harrisoni species group is thus in need of taxonomic review.
DEVICES, SYSTEMS AND METHODS FOR TISSUE ANALYSIS, LOCATION DETERMINATION AND TISSUE ABLATION

An exemplary tissue detection and location identification apparatus can include, for example, a first electrically conductive layer at least partially surrounding a lumen, an insulating layer at least partially surrounding the first electrically conductive layer, and a second electrically conductive layer circumferentially surrounding the insulating layer, where the insulating layer can electrically isolate the first electrically conductive layer from the second electrically conductive layer. A further insulating layer can be included which can at least partially surrounding the second electrically conductive layer. The first electrically conductive layer, the insulating layer, and the second electrically conductive layer can form a structure which has a first side and a second side disposed opposite to the first side with respect to the lumen, where the first side can be longer than the second side thereby forming a sharp pointed end via the first side at a distal-most portion.
SEISMIC PERIMETER BRACE

A seismic bracket for supporting ends of suspended ceiling grid runners from a wall comprising a stamped sheet metal body, the body having a horizontally extending portion and a vertically extending portion, the vertically extending portion, in its installed position, rising above the top of a standard grid runner a distance at least 1-1/2 times the height of such standard grid runner, the vertically extending portion having two sections generally coextensive in the vertical direction, a first section being integral with the horizontally extending portion and a second section arranged to be in a vertical plane that intersects a vertical plane occupied by the horizontally extending portion, the horizontally extending portion being arranged to support a grid runner to move longitudinally a limited distance, the second section of the vertically extending portion having an aperture for securing the bracket to the wall at a location substantially above the grid tee.
Multiscale design of porous implants with a biomimetic functionally graded cellular material

Endosseous implants are now widely used in clinical practice to restore joint functionality or to replace missing teeth. Despite their increasing success, implant long-term stability remains a concern and it is difficult to predict the surgical outcome so far. A major cause of failure comes from bone resorption secondary to stress shielding, which arises from the mismatch of the mechanical properties between the implant and the surrounding bone tissue. To overcome this problem, MIDPOINT proposes to design porous implants that will have a biomimetic cancellous bone microstructure with a nonhomogeneous distribution of its material properties. The optimal design will produce implants with mechanical and microstructural properties similar to that of the bone, which will result in an improvement of the effectiveness of osseointegration phenomena.
A work methodology that combines multiscale computational modelling and experimental work for the formulation, construction, verification and validation of computational models is proposed. This methodology will comprise i) the design of new biomimetic microstructures that replicate the geometrical properties of the natural trabecular bone using a generative design approach, the Voronoi tessellation approach; ii) the development of an iterative computational method to predict the fatigue life of the artificial microstructures directly at the macroscale employing damage accumulation models coupled with artificial neural networks; and iii) the construction of multiscale models of bone-implant systems to optimize the implant microstructure locally in order to achieve a desirable mechanical response and functional environment for bone ingrowth and, therefore, minimize bone resorption. These techniques will be employed to design implants and scaffolds that, together with medical imaging techniques, can be personalized to the needs of each patient and directly printed at the medical institution using additive manufacturing techniques.
Technology for sustainability in organisations: case studies on agricultural production

In the contemporary world, technological solutions to the ecological challenges have received a central role. Due to the robust political commitment to technological progress in environmental policy and related path dependencies, modern societies and organisations are increasingly contingent on technological systematizations. The development and adoption of increasingly advanced technological products and processes are taken for granted, and policies persist largely unquestioned. For instance, in the context of agriculture, the development and implementation of new technology is considered to be central in the future of food production and particularly critical in support of sustainable modes of agricultural production.

Current governmental incentives and management models are to encourage inertia rather than transitions towards sustainable agricultural production. Despite several ecological benefits of less intensive farming methods and the rising consumer demand on sustainable produce, market shares of non-conventionally produced food remain small. The often-higher, short-term productivity of intensive agriculture, as an outcome of greater use of external input factors, such as chemical fertilizers and pesticides, is too attractive to farmers struggling with profitability.

This study hypothesises that in addition to the lack of organisational resources of the farmers (including economic capital, knowledge, and awareness of the ecological challenges) and public policies, a more fundamental barrier to developing sustainable modes of production might prevail, namely technological optimism. With high expectations on future solutions by means of  clean technology, agricultural intensification efforts today may continue without interreptions. This study asks: how ecological is the kind of change that technologies are able to deliver?
Improving accessibility of services of general interest – organisational innovations in rural mountain areas

The maintainance of a spatially and socially equal accessibility to services of general interest (SGI) is a core issue to the functionality of mountain areas. However, the ongoing territorial concentration of SGI leads to a vicious circle of further deterioration in the quality of provision which in turn causes a decreasing demand in the existing services. The withdrawal of SGI has many negative consequences for the affected regions of which a reduced functionality, competitiveness and a higher amount of motorised mobility are the most pertinent. The ACCESS project therefore aims at improving the accessibility to SGI in sparsely populated, mountain areas mainly by finding new forms of organisation of SGI, using Information and Communication Technologies (ICT) and fostering demand oriented, integrated mobility systems. To achieve these ambitious goals, ACCESS builds on a transnational approach and on participatory methodologies to assess the specific demands of stakeholders on different levels.
Deutsch als Teil der Mehrsprachigkeit Brasiliens: ein Praxisbericht

No AccessDeutsch als Teil der Mehrsprachigkeit Brasiliens: ein PraxisberichtProf. Karen Pupp SpinasséProf. Karen Pupp Spinassé Universidade Federal do Rio Grande do Sul Brasilien Karen Pupp Spinassé ist Professorin für Deutsch als Fremdsprache an der Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre/Brasilien. Ihre Forschungsschwerpunkte sind Mehrsprachigkeit und zweisprachiger Unterricht, Migrationssprachen und Sprachenpolitik im schulischen Kontext. Sie koordiniert die deutschen Kurse an der Universität und ist Gründungsmitglied des brasilianischen Zentrums für Deutschland- und Europastudien (CDEA UFRGS-PUCRS).Search for more papers by this authorPublished Online:Jul 2022https://doi.org/10.14220/odaf.2022.38.1.235SectionsPDF/EPUB ToolsAdd to favoritesDownload CitationsTrack Citations ShareShare onFacebookTwitterLinkedInRedditEmail About Previous article Next article FiguresReferencesRelatedDetails Download book coverVolume 38Issue 1–2July 2022 ISSN: 2196-9167eISSN: 2197-6015HistoryPublished online:July 2022 PDF download
Fibre optic nonlinear technologies

Fibre-optic communication systems form the backbone of the world’s communication infrastructure as they provide for lion fraction (more than 99%) of the global data traffic. The ongoing exponential growth in network traffic, however, is pushing current technology, whose data rates had increased over several decades, towards its limits. It is widely accepted that the nonlinear transmission effects in optical fibre are now a major limiting factor in modern fibre-optic communication systems. Nonlinear properties of the optical fibre medium limit the conventional techniques to increase capacity by simply increasing signal power. Most of the transmission technologies utilized today have been originally developed for linear (wired or wireless) communication channels. Over the past several decades, significant improvements in data rates were obtained by improvements and modifications within the overall linear transmission paradigm. However, there is much evidence that this trend is going to end within the next decade due to fibre nonlinearity. There is a clear need for radically different approaches to the coding, transmission, and processing of information that take the nonlinear properties of the optical fibre into account. This also requires education and training of a new generation of optical communication engineers and specialists with knowledge on nonlinear methods and techniques. 

The EID FONTE R&D goals will be focused on development of disruptive nonlinear techniques and approaches to fibre-optic communications beyond the limits of current technology. The project will make important innovative steps in development of the technique of the nonlinear Fourier transform (NFT) and its implementation in the practical communication systems. The R&D tasks will be carried out along with training of PhD students in the leading research centres in Europe with industry focused projects with 50% of time spent in the world leading telecom  centre - Nokia Bell Labs Germany.
CELL SENSOR HAVING MULTIFUNCTIONAL REACTIONS FOR THE DEFINITION OF QUALITY CRITERIA DURING THE PRODUCTION OF MATERIALS

Disclosed is a method for producing a cell sensor system used for defining quality criteria during the production of materials. Said method is characterized by the following steps: a) first cells of a specific type are cultivated in standard culture conditions (control group); b) second cells of said specific type are cultivated on/in/between different materials that are to be tested (test group); c) the cells are harvested; d) the gene activities of the cells of the control group and the cells of the test group are determined; e) the gene activities of the test group are compared to those of the control group; f) the genes are identified in which there is a difference in the gene activities between the control group and the test group; g) a microarray is established using the identified genes having a different gene activity as a gene profile, said established microarray being defined as a standard for the specific cell type; and h) third cells of the specific cell type are provided as a cell sensor.
(Ultra)Sound interfaces and low energy integrated sensors

The SILENSE project will focus on using smart acoustic technologies and ultrasound in particular for Human Machine- and Machine to Machine Interfaces. Acoustic technologies have the main advantage of a much simpler, smaller, cheaper and easier to integrate transducer. The ambition of this project is to develop and improve acoustic technologies beyond state-of-the-art and extend its application beyond the mobile domain to Smart Home & Buildings and Automotive domains.
In this project, it will be proven that acoustics can be used as a touchless activation and control mechanism, by improvement or development of different smart acoustic technology blocks (hardware, software and system level) and integrate these blocks at system level.

At technology level, the SILENSE project will:
-	Adapt and improve cost, performance, directivity and power consumption of (MEMS) acoustic transducers (incl. testing and qualification)
-	Heterogeneously integrate arrays of acoustic transducers with other electronics, using advanced (3D) packaging concepts
-	Develop smart algorithms for acoustical sensing, localization and communication
-	Combine voice and gesture control by means of the same transducer(s)

At application level the SILENSE project will:
-	Apply acoustical sensing for touchless activation/control of mobile devices, wearables and, more in general, IoT nodes. 

The project links to Smart Systems Integration (B4), and refers also to application application-related topics, such as Smart Mobility and Smart Society. The application scope of the developed technologies is broader and comprises more societal domains, such as smart home/buildings, smart factories (i.e. Smart Production) and even Smart Health. Furthermore, a clear cross reference with Semiconductor Process, Equipment and Materials (B1) is established in view of the heterogeneous integration of technology blocks. Conventional silicon technologies will be combined with printed (flexible, large area electronics).
Bmx-Targeted ligand-drug conjugates for prostate cancer therapy

Standard of care strategies for the treatment of cancer still relies heavily on non-specific radiation and chemotherapy. These treatments are commonly associated with severe toxicities and in many cases only offer limited benefit for the patient. The targeted delivery of radionuclides, cytotoxic drugs and pro-inflammatory cytokines into malignant tissue, on the other hand, can markedly improve the therapeutic index and overall efficacy of such substances. Whilst monoclonal antibodies are the most widely used delivery vehicles to date, low molecular weight targeted agents are emerging as a promising alternative to antibody-based drug delivery. These ligands have negligible immunogenic risk and are easier to chemically modify enabling fine tuning of their ADME profile. As a result, it is possible to achieve a time dependent release of the cytotoxic payload at the target tissue maximizing its therapeutic efficacy while producing minimal damage to healthy cells.  Most importantly, depth of tumour penetration and tumour-to-blood distribution ratio after injection should be significantly superior.
We therefore propose to systematically investigate the targeting  performance of bone marrow tyrosine kinase in chromosome X (BMX) ligands for the targeted delivery of cytotoxic drugs into BMX-overexpressing tumours, namely prostate cancer. This project aims at (1) demonstrate that a BMX ligand can selectively accumulate in BMX-overexpressing cancers; (2) developing a general chemical approach for building safe ligand-drug conjugates (LDCs); and (3) when site-specifically conjugated to cytotoxic drug, this novel LDC is highly effective for the treatment of prostate cancer. This project is expected to explore new avenues for drug delivery systems since the concepts here proposed go beyond prostate cancer therapy as they can be applicable to any ligand that interferes with up-regulated disease-related pathways.
Wide band gap innovative sic for advanced power

WInSiC4AP core objective is to contribute in developing reliable technology bricks for efficient and cost-effective applications addressing social challenges and market segments where Europe is a recognized global leader as well as automotive, avionics, railway and defence.
WInSiC4AP approach is to rely on the strength of vertical integration allowing optimization, technologies fitting application requirements, developing the full ecosystem and approach relevant issues as reliability in the full scope. That enhances the competitiveness of EU- Industries as well as TIER1 and TIER2 down to the value chain in a market context where other countries today, such as the USA or Japan, are advancing and new players accessing SiC enter in the market.

New topologies and architecture will be developed for  targeted  application  simulating operational environment, at laboratory level, driving the needed and still missed technologies, components and demonstrators to fill the gap between current state of the art and the very high demanding specifications.
WInSiC4AP framework has been built so that companies working in different domains (i.e. automotive car maker and TIER1-2 and avionics, railway and defence TIER1-TIER2) and in the vertical value chain (semiconductor suppliers, companies manufacturing inductors and  capacitors)  as well as academic entities and laboratories will collaborate to co-design solutions, solve problems and exchange know-how, such that unforeseen results may also  emerge.
WInSiC4AP will be supported with synergy between ECSEL JU and ESI funding enabling complementary activities with relevant economic and social impact envisage in a less development region of Union.
Metaphorical narratives in dementia discourse

Research on dementia discourse has shown how our attitudes, views and words have a positive or negative influence on the well-being of People Living With Dementia (PLWD).  In 2013, Alzheimer Europe’s report underlined worrying ethical risks of metaphor use in dementia narratives, including stigmatisation, stereotyping and social exclusion. Yet we still do not have an adequate understanding of these potential risks and of the ethical responsibility needed when ‘metaphorical narratives’ (MNs), or metaphorical scenarios, are used in dementia discourse between scientists, journalists, caregivers and PLWD. This may increase risks of conflict and misunderstanding between these different social agents. It also hinders developing a responsible (i.e., respectful) use of MNs in dementia discourse, complying with the EU H2020 emphasis on Responsible Research and Innovation and healthy ageing.
MeNDD develops an innovative interdisciplinary approach combining the experienced researcher’s historical-philosophical work on MNs in the biosciences across times and in responsible health communication with the supervisor’s new model of metaphor in discourse. It joins together a historical-epistemological approach, corpus research and informant analysis to build an innovative model of ‘social awareness of dementia MNs’. It shows how science, the media, professional caregivers and PLWD use two-major dementia MNs of ‘cognitive decline’ and ‘brain plasticity’ while balancing the potential risks and the ethical responsibility in differentiated, occasionally diverging ways. The model reveals the major patterns of social awareness of the two MNs in dementia discourse, highlighting potential risks of conflict and misunderstanding between the different groups. It is designed for utilisation in enhancing a responsible dementia discourse: it can be applied in health professionals’ training, in healthcare and in public campaigns to reduce risks of miscommunication in practice.
Effects of Short-Term Quercetin Supplementation on Soldier Performance

The purpose was to assess the short-term effects of quercetin supplementation on aerobically demanding soldier performance. In a double-blind crossover study, 16 male soldiers performed 3 days of aerobically demanding exercise under 3 conditions: Baseline (B), Placebo (P), and Quercetin (Q). Day 1 was a treadmill V[Combining Dot Above]O₂peak test. Days 2 and 3 were identical, consisting of 75 minutes of loaded treadmill marching (LM) and a subsequent cycling time trial (TT) to complete 200 kJ of work. After B condition, the soldiers consumed 2 energy bars, each containing 0 mg (placebo) or 500 mg of quercetin (1,000 mg·d⁻¹) for 8.5 days. Beginning day 6 of supplementation, the soldiers performed the 3 exercise days. There was a significant (p < 0.05) increase in plasma Q after Q supplementation. Repeated measures analyses of variance revealed no differences after P or Q supplementation as compared with B in V[Combining Dot Above]O₂peak (B = 48.9 ± 1.1, P = 49.3 ± 1.1, Q = 48.8 ± 1.2 ml·kg⁻¹·min⁻¹) or TT time (B = 18.4 ± 1.0, P = 18.5 ± 1.1, Q = 18.3 ± 1.0 minutes [mean day 1 and day 2]). The respiratory exchange ratio during LM did not differ across treatments (B = 0.87 ± 0.03, P = 0.87 ± 0.03, Q = 0.86 ± 0.04 [mean day 1 and day 2]). Ratings of perceived exertion were not affected by Q supplementation during the V[Combining Dot Above]O₂peak test, LM or TT. Supplementation of 1,000 mg·d⁻¹ of quercetin for 8.5 days had no positive effect on aerobically demanding soldier performance. It is possible that a different dosing regimen, a combination of antioxidants or a different form of quercetin supplementation, may be needed to produce an increase in soldier performance.
Wind energy resources on Phuquoc Island, Vietnam

ABSTRACTThis study analyzes the wind energy resources on Phuquoc Island, Vietnam. Daily wind data are collected from 2005 to 2011 in this study. The annual mean speed and power density are 6 m/s and 355 W/m2, respectively. Results show that more than 35% of the wind energy comes from the northwest. In this study, a 75 MW wind farm with 25 wind turbines is simulated by using the WAsP 10 program. The wind farm can produce over 189.636 GWh annually. In addition, the effects of wind disturbance and three-phase short circuit of the grid are analyzed using the ETAP 7.0 program.