SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
System and Method for Refuelling Compressed Gas Pressure Vessels Using a Liquid Piston

A pressure vessel refuelling system enables fast refuelling of Compressed Natural Gas (CNG) fuel tanks. The system includes a pressure vessel having a gas inlet/outlet port and a liquid inlet/outlet port; a first liquid at least partially filling the pressure vessel; a liquid layer of a second liquid floating on top of the first liquid, wherein the second liquid is immiscible with the first liquid; a gas at least partially filling the pressure vessel above the liquid layer of the second liquid, the gas in fluid communication with the gas inlet/outlet; and a pump in fluid communication with the liquid inlet/outlet of the pressure vessel, whereby the first liquid can be pumped or returned to/from storage into or out of the pressure vessel.
Theoretical and experimental study of the incorporation of tobramycin and strontium-ions into hydroxyapatite by means of co-precipitation

• We investigate incorporation of tobramycin into hydroxyapatite using co-precipitation by theory and experiment. • The drug molecule shows larger adsorption energy on a submicron HA surface compared to a TiO 2 surface. • Strontium substitution allows for production of thinner coatings with enhanced drug incorporation capacity. Antibiotic incorporation into hydroxyapatite (HA) coatings by co-precipitation and the impact of bone relevant doping elements on the adsorption kinetics are investigated from both theoretical and experimental points of view. Tobramycin interactions with bioactive TiO 2 and HA surfaces are analyzed using density functional theory. According to the calculations, the drug molecule has larger adsorption energy than the Ca + ion on both surfaces under study in Phosphate Buffered Saline (PBS). The results support the experimental observations that HA nucleation and growth are strongly limited on TiO 2 surfaces in the presence of clinically relevant antibiotic concentrations in PBS. The drug molecule is more likely to adopt parallel arrangement onto the HA surface, as the adsorption energy of such arrangement is higher compared to a perpendicular one. Strontium substitution of the HA surface is found to results in a weaker drug–surface interaction, and leads also to a decrease in coating thickness. However, the presence of strontium gives rise to a coating morphology with enhanced drug incorporation capacity and slower antibiotic release compared to non-substituted, co-precipitated counterparts. Our theoretical calculation results were found to be in excellent agreement with experimental data and provide a powerful tool to understand the interaction mechanism between drug and different surface chemistries necessary for development of future versatile orthopedic and dental implant surfaces.
Estudio de factibilidad para la producción industrial y comercialización de un aderezo picante y dulce sabor a mango "Mangífera Indica" para ser distribuido en cadenas de autoservicios

This study is based on the use of mango as a raw material for the production of a spicy and sweet salad dressing.
The feasibility of implementing a production plant that has as a business strategy the distribution in supermarkets all over the country.
According to surveys conducted on a sample of 138 individuals from middle - high social strata and an age range of 18 to 65 a total market of dressings 1'006.780 units per month was determined, and on this basis it was established a production target and market penetration of 1% for the start of the project.
Once the technical, economic and financial studies were done, the results were obtained as an internal rate of return of 48.3% and a net present value of investment 170.782,10usd over a period of five years, so the project feasible and significantly cost effective when compared with a 9% rate of opportunity money annually.
CIVIC ENERGY FUTURE: SUSTAINABLE LOCAL ENERGY COMMUNITIES

The main challenge of the programme area , at international level,  is to reduce carbon emission and  to improve energy efficiency in public sector through innovative practices and tools (the European goal of “reducing of 20% the greenhouse gas emissions, of 20% the energy demand that is produced from renewable sources, of improving of 20% the energy efficiency compared to 1990 and by 2020, Climate and Energy package, UE"). A vision also shared by the Municipalities through the “Covenant of Mayors” (www.eumayors.eu). Goals that are difficult to achieve if we don't promote and implement bottom-up participation paths, based on the citizens’ mobilisation. In fact, considering the public spending reduction, the role of the users, from the P.A. to the municipalities and private sectors, citizens and businesses, become fundamental for the goals achievement at global and local level .The project,in line with the Directive (EU) on the energy efficiency 2018/844 of 30 May, will  contribute to improving the energy efficiency and renewable energy usage through the development of “local community of active energy consumers ” (LEC) which cooperates with municipalities (public-private partnerships), by encouraging the sustainable Municipalities models through local actions in accordance with the change in the citizens behavior. (overall objective).To this end will be created n.4 LEC (SO1) that elaborate and commit themselves to implement a shared common action plan finalized to Energy efficiency in a sustainable and ethics way related  to the territory’s needs (OS2).The Common Action plan will become a political commitment of the municipalities and LECs through the signing of an Agreement The application of the common action plan will be shown through the implementation of n.4 pilot projects in identified public buildings /areas that includes the active involvement of 4 LEC(OS3)Project outputs will consist in the implementation of n. 4 pilot projects.
A device enabling quantification of molecular and nanoparticle diffusion within thin solvated films

The objective of the DIFFUSION project is to develop an easy-to-use device to analyse diffusion processes within thin solvated films. This new analytical tool will overcome a current bottleneck in the development of functional coatings for a wide range of applications, from fundamental research in biophysics and microbiology to real-life applications in biomaterials and paints.

Driven by analytical needs during the ERC Starting Grant project JELLY my team and I conceived the DIFFUSION technology. The technology has the potential to enhance research and development in industry and academia – in material sciences and engineering, physics, chemistry and biology – wherever functional thin films/coatings are developed or used. It enables the analysis of molecular and nanoparticle diffusion within thin solvated films, thus providing new information that is instrumental to the development and quality control of films/coatings with superior performance and new functions yet has so far been challenging to assess. The technology is conceived as a modular add-on device that enhances the capabilities of the users' existing existing optical microscopy setups. An initial market analysis has already shown that there is broad interest in the method in academia and industry, and that the solution we aim to offer would be attractive. 

This Proof of Concept grant is required to develop a second-generation prototype to demonstrate that a cost-effective and easy-to-use device is feasible, to demonstrate its added value with selected application examples covering target research and development areas, and to develop a commercialisation plan including the identification of an industrial partner that is ready to build on the second-generation prototype and rapidly move a device into production and commercialisation.
Future mobility values and culture

REBALANCE will conduct an open deliberative forward-looking exercise towards a transformative transport policy in favour of a paradigm shift in mobility. It will push for the more effective ponderation of emerging social values not yet fully considered in transport policymaking, and a better alignment with the SDGs and the mounting concerns about climate change. To do so, REBALANCE will launch a Europe-wide high-level discussion on all the fundamentals of transport policy embedded in the current mobility paradigm. By critically reviewing the present -also in the light of the recent COV19 pandemic which drastically affected our lifestyles- the project will mobilise around the New Mobility Cultures and Policies Hub a wide network of transport experts and stakeholders to discuss and converge on a shared vision over a more sustainable path and jointly devise a roadmap for a new transport paradigm. The novelty, but also the strength of REBALANCE lays in the unconventional array of multidisciplinary thinkers that will contribute to the debate. As a new paradigm requires opening the windows of imagination, the project will count on the contribution of a multifaceted group of renowned philosophers, sociologists, social psychologists, geographers, and jurists that have not necessarily been involved in the past and current transport research debates. Their role is to provoke and shake the foundations of the current way of thinking and fertilize the continuing cultural and political deliberative process. The ultimate ambition is to reflect the joint effort in a Manifesto for a New Mobility Culture, to make sure that shared values and beliefs of Europeans are embedded in the fundamentals of the new transport policy, and lay the foundations for a long-term cultural change in the way people understand mobility and take decisions on transport policies.
Comparative life cycle assessment of renewable energy systems for heating and cooling

Abstract Renewable systems for heating and cooling (RES-HC) systems in last ten years have gradually increased their importance and their presence in the global heating ventilation and air conditioning (HVAC) market. Many energetic analysis and impact assessments have been made, which have demonstrated the convenience, respect to traditional HVAC systems, of solutions such as solar thermal or low enthalpy geothermal systems in terms of: energy consumption reduction, renewable energy use increase and emissions decrease. However, the several analysis made, up to date, only have considered the operation period of such systems, and consequently the comparison has been made only in terms of energy vectors used, omitting materials, components and processes. This paper aims to give a new perspective, showing how a correct environmental analysis should take into account all the life cycle of a system, from the cradle to grave, also if the system concerns a renewable energy source. In the specific case, a Life Cycle Assessment (LCA) will be presented, focusing on two currently popular RES-HC systems: solar thermal and low enthalpy geothermal, compared to the same functional unit. The results of this analysis could be a good starting point for future work on impact assessment of more complex and integrated HVAC systems.
Measurement-Based dynamic control of mesoscopic many-body systems

Quantum control is an ambitious framework for steering dynamics from initial states to arbitrary desired final states. It has over the past decade been used extensively with immense success for control of low- dimensional systems in as varied fields as molecular dynamics and quantum computation. Only recently have efforts been initiated to extend this to higher-dimensional many-body systems. Most generic quantum control schemes to date, however, put quite heavy requirements on the controllability of either the system Hamiltonian or a set of measurement operators. This will in many realistic scenarios prohibit an efficient realization.

Within this proposal, I will develop a new quantum control scheme, which is minimalistic on system requirements and therefore ideally suited for the efficient and reliable optimization of many-body control problems. The fundamentally new ingredient is the total quantum evolution dictated by a combination of fixed many-body time evolution and the precise knowledge of the quantum back-action due to repeated quantum non-destruction (QND) measurements of a single projection operator. 
The main focus of this proposal is theoretical and experimental quantum engineering of the dynamics in systems, which are sufficiently small to calculate the measurement back-action exactly and sufficiently large to have interesting many-body properties.
Recent experimental advances in single site manipulation of bosons in optical lattices have enabled the high fidelity preparation exactly such mesoscopic samples of atoms (5-50). This forms an ideal starting point for many-body quantum control, and we will i.a. demonstrate engineering of quantum phase transitions and preparation of highly non-classical Schödinger cat states.

Finally, using the results from an online graphical interface allowing users of the internet to solve quantum problems we will attempt to build next-generation optimization computer algorithms with a higher level of cognition built in.
Adaptive adas to support incapacitated drivers mitigate effectively risks through tailor made hmi under automation

ADAS&ME (“Adaptive ADAS to support incapacitated drivers &Mitigate Effectively risks through tailor made HMI under automation”) will develop adapted Advanced Driver Assistance Systems, that incorporate driver/rider state, situational/environmental context, and adaptive interaction to automatically transfer control between vehicle and driver/rider and thus ensure safer and more efficient road usage. To achieve this, a holistic approach will be taken which considers automated driving along with information on driver/rider state. The work is based around 7 provisionally identified Use Cases for cars, trucks, buses and motorcycles, aiming to cover a large proportion of driving on European roads. Experimental research will be carried out on algorithms for driver state monitoring as well as on HMI and automation transitions. It will develop robust detection/prediction algorithms for driver/rider state monitoring towards different driver states, such as fatigue, sleepiness, stress, inattention and impairing emotions, employing existing and novel sensing technologies, taking into account traffic and weather conditions via V2X and personalizing them to individual driver’s physiology and driving behaviour. In addition, the core development includes multimodal and adaptive warning and intervention strategies based on current driver state and severity of scenarios. The final outcome is the successful fusion of the developed elements into an integrated driver/rider state monitoring system, able to both be utilized in and be supported by vehicle automation of Levels 1 to 4. The system will be validated with a wide pool of drivers/riders under simulated and real road conditions and under different driver/rider states; with the use of 2 cars (1 conventional, 1 electric), 1 truck, 2 PTWs and 1 bus demonstrators. This challenging task has been undertaken by a multidisciplinary Consortium of 30 Partners, including an OEM per vehicle type and 7 Tier 1 suppliers.
Common good air

Port areas are important to the economy and have to withstand strong environmental pressures, making it necessary to protect the environment and people’s health.  The shared challenge is to promote a reduction in polluting emissions deriving from port activities and, in particular, from ships.
 The general goal of this project is to contribute to preserving or improving air quality in the areas overlooking ports within the cooperation area, at the same time as promoting the sustainable growth of port activities, in compliance with current legislation and European environmental policies. 
The project will create a cross-border centre to monitor air quality in ports, through an innovative approach based on a comparison between the various tools used, on the analysis and implementation of predictive models, on the harmonisation of survey methodologies and on the sharing of data. The possible ways to mitigate emissions will also be defined by involving the relative stakeholders.
 Port authorities, shipping companies, harbour master’s offices and policymakers will benefit from an innovative tool to support the decision-making process, designed specifically to help port areas implement preventive actions to protect the environment, in line with current regulations and with a view to achieving sustainable growth.
 The improvement in environmental conditions will have positive effects on the health and quality of life of local residents and on the development of economic activities linked to natural marine resources and tourism. Due to the fact that shipping is intrinsically transnational, and considering that emissions deriving from port activities affect the territory on very large spatial scales, this project needs to be cross-border in order to identify where to intervene as a priority, ensuring maximum impact on all of the eligible territory.
New mitochondrial DNA mutations in tRNA associated with three severe encephalopamyopathic phenotypes: neonatal, infantile, and childhood onset

The reported cases showed clinical, biochemical, histopathological, and molecular features lending support to the hypothesis of a pathogenic effect of the detected mutations. Case 1 was a neonatal presentation who showed multiple mitochondrial respiratory chain enzyme defects in muscle associated with a new homoplasmic m.5514A > G transition in the tRNA(Trp) gene. Case 2 was a late infantile presentation who also showed mitochondrial respiratory chain enzyme deficiencies in muscle together with a new m.1643A > G tRNA(Val) mutation in homoplasmy. Case 3 showed a MERRF phenotype presented in childhood associated with the once previously reported m.15923A > G mutation in heteroplasmy in all the tissues studied.
SEAL FOR BLOWOUT PREVENTER WITH SELECTIVE DE-BONDING

A seal and a method of manufacturing a seal for a blowout preventer. The seal includes a rigid material insert disposed within an elastomeric body, with at least a portion of the rigid material insert selectively de-bonded from the elastomeric body.
High precision and performance heliostat for variable geometry fields of thermosolar plants

TEWER has verified that solar fields implemented today are calculated considering a unique design of heliostat and presenting heliostat is not only characterized by the energy which is able to reflect but by how it is reflected. The configuration of the solar field and the influence of geometrical factors are directly related to the production and it is essential to take into account regarding the design, all weather operation conditions in order to get a high technology performance.
Until today, although the market is asking for it, there is no product that allows variable geometry designs of solar field, allowing them to increased the energy efficiency and the overall performance from the field, improving the relation benefit/cost of current systems.
TEWER aims to use this need to sell their pioneer solution in the field of engineering for solar power energy by concentration to be able to demonstrate management companies of solar plants that their product offers a much more efficient and cost-effective technology than the one that exists currently.
IDENTIFICATION OF OLIGONUCLEOTIDES FOR THE CAPTURE, DETECTION AND QUANTITATION OF WEST NILE VIRUS.

West Nile virus capture oligonucleotides, primers and probes derived from conserved regions of the West Nile virus genome are disclosed. Also disclosed are nucleic acid-based assays using the capture oligonucleotides, primers and probes.
SL2-like spliced leader RNAs in the basal nematode Prionchulus punctatus: New insight into the evolution of nematode SL2 RNAs

Spliced-leader (SL) trans-splicing has been found in all molecularly characterized nematode species to date, and it is likely to be a nematode synapomorphy. Most information regarding SL trans-splicing has come from the study of nematodes from a single monophyletic group, the Rhabditida, all of which employ SL RNAs that are identical to, or variants of, the SL1 RNA first characterized in Caenorhabditis elegans. In contrast, the more distantly related Trichinella spiralis, belonging to the subclass Dorylaimia, utilizes a distinct set of SL RNAs that display considerable sequence diversity. To investigate whether this is true of other members of the Dorylaimia, we have characterized SL RNAs from Prionchulus punctatus. Surprisingly, this revealed the presence of a set of SLs that show clear sequence similarity to the SL2 family of spliced leaders, which have previously only been found within the rhabditine group (which includes C. elegans). Expression of one of the P. punctatus SL RNAs in C. elegans reveals that it can compete specifically with the endogenous C. elegans SL2 spliced leaders, being spliced to the pre-mRNAs derived from downstream genes in operons, but does not compete with the SL1 spliced leaders. This discovery raises the possibility that SL2-like spliced leaders were present in the last common ancestor of the nematode phylum.
Myocardial oxidative metabolism, blood flow and efficiency in rapid pacing induced heart failure in dogs.

Heart failure is the final common pathway for most forms of heart disease, and is characterized by a reduced energy status. Myocardial oxygen consumption (MV02) is closely related to the main determinants of systolic function (heart rate, pressure and contractility). The aim of the study was to compare myocardial blood flow, metabolism and mechanical efficiency in rapid pacing induced heart failure in dogs.5 dogs were paced for 3 weeks at 240 bpm, with regular follow up of hemodynamic characteristics. Coronary blood flow and oxidative metabolism were evaluated with [(15)O] water and [(11)C]acetate clearance respectively, in baseline conditions (B) and after 3 weeks of rapid pacing (3 wk RP) using positron emission tomography.Three weeks of rapid pacing in a dog model resulted in a severely depressed left ventricular function (LV dP/dtmax 3698 ± 314 mmHg (B) vs. 1365 ± 103 mmHg (3 wk RP)). On the contrary myocardial blood flow 1.29 ± 0.11 ml/min/g (B) vs. 1.05 ± 0.07 ml/min/g (3 wk RP) and oxidative metabolism 0.178 ± 0.1 min(-1) (B) vs. 0.161 ± 0.1 min(-1) (3 wk RP) remained essentially unchanged, indicating a reduced efficiency and a change in O2 utilization.Heart failure induced by rapid ventricular pacing in dogs provokes a clearly reduced mechanical efficiency, illustrating the occurrence of a metabolic remodeling in heart failure induced by rapid pacing.
Qur'Anic commentary: an integrative paradigm

QuCIP will deliver the first historical-critical commentary on a sizable portion of the Qur’an in English, covering the three longest and most complex compositions in the Islamic scripture, surahs 2–4, as well as the short opening surah 1. The project will thereby put forward a pioneering proof of concept for an integrative exegetical approach capable of addressing three core dimensions of the Qur’an: the compositional structure of Qur’anic texts, the intricate processes of literary growth and redactional expansion by which many of them have been shaped, and the theological concerns governing the Qur’an’s appropriation of antecedent (especially Jewish and Christian) ideas, traditions, and literary forms. Pre-modern Islamic exegesis will be critically scrutinised as a valuable repository of close scriptural reading, even if its premises and conclusions are not always persuasive to a modern historian. The result will be a paradigmatic benchmark transforming the methodological toolkit of the discipline.

In realising this ambitious project, the PI will be supported by three postdoctoral scholars. Two of them will undertake foundational research into the Qur'an's compositional grammar and into Qur’anic law. The third postdoctoral researcher will support the PI’s engagement with the voluminous Islamic exegetical literature and write a reception history of surah 4. The project team will furthermore produce an edited volume or special journal issue.