SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Enhancing City Transportation Services Using Cloud Support

Smart cities will provide enhanced monitoring of crucial infrastructure resources, connectivity to users and advanced information services. Thanks to gathered data the quality of traditional services and infrastructures will be improved, and further services can emerge, such as novel urban transportation services. This paper devises a solution that enforces the cooperation between mobile devices and cloud infrastructures with the aim to bring public transportation where the people need it. Thanks to smart phones, sensing user locations, a request for transportation vehicles can be sent to a cloud-based intelligence, which filters and serves requests according to available transport routes, and their adaptation to user needs. Then, the available transportation vehicles will be timely alerted to operate accordingly.
COMPUTATIONAL APPLICATIONS IN MASONRY STRUCTURES: FROM THE MESO-SCALE TO THE SUPER-LARGE/SUPER-COMPLEX

Masonry structures constitutes a large portion of the built heritage around the world, from the past and still today. Therefore, understanding their structural behavior has a crucial role in preserving the historical characteristics of many of those structures and in addressing the requirements for housing and sustainable development. However, due to its composite and highly non-linear nature, it has been a challenge for engineers to analyze masonry structures. This lecture will provide an extensive overview on computational applications, including the usual micro-modeling approaches (in which masonry constituents, i.e. unit and joint, are represented separately), macro-modeling (in which masonry constituents are smeared in a homogeneous composite), homogenization techniques (in which upscaling from micro to macro is adopted) and structural component models (in which the global behavior of a full structural element is represented). Different phenomena will be addressed including multi-physics and mechanics (statics, slow dynamics or earthquakes, and fast dynamics or impact and blast). Finally, engineering applications will be presented, addressing full scale applications in large monumental structures, regarding safety assessment and strengthening.
Radial cutting tools for cutting thick-walled tubular members

Relatively thick-walled (or solid) tubular members may be cut by cutting tools which include a frame assembly which is concentrically positionable (either interiorly or exteriorly) relative to the tubular member to be cut. A radial cutting assembly defines a cutting plane and is connected to the frame so as to be rotationally movable about the longitudinal axis of the tubular member to be cut. The radial cutting assembly carries a bit subassembly (preferably a pair of generally radially opposed cutting assemblies) for cutting the tubular member. A drive/indexing assembly is provided so as to rotate the rotatable ring (and thereby cause the radial cutting assembly to move orbitally about said tubular member), and index the bit radially toward the tubular member in response to rotational movement of the radial cutting assembly.
NO TIME FOR DEAD TIME: TIMING ANALYSIS OF BRIGHT BLACK HOLE BINARIES WITH<i>NuSTAR</i>

Timing of high-count rate sources with the NuSTAR Small Explorer Mission requires specialized analysis techniques. NuSTAR was primarily designed for spectroscopic observations of sources with relatively low count-rates rather than for timing analysis of bright objects. The instrumental dead time per event is relatively long (~2.5 msec), and varies by a few percent event-to-event. The most obvious effect is a distortion of the white noise level in the power density spectrum (PDS) that cannot be modeled easily with the standard techniques due to the variable nature of the dead time. In this paper, we show that it is possible to exploit the presence of two completely independent focal planes and use the cross power density spectrum to obtain a good proxy of the white noise-subtracted PDS. Thereafter, one can use a Monte Carlo approach to estimate the remaining effects of dead time, namely a frequency-dependent modulation of the variance and a frequency-independent drop of the sensitivity to variability. In this way, most of the standard timing analysis can be performed, albeit with a sacrifice in signal to noise relative to what would be achieved using more standard techniques. We apply this technique to NuSTAR observations of the black hole binaries GX 339-4, Cyg X-1 and GRS 1915+105.
Targeting the epigenome: towards a better understanding of disease pathogenesis and novel therapeutic strategies in multiple sclerosis

Multiple Sclerosis (MS) is a leading cause of unpredictable and incurable progressive disability in young adults. Although the exact cause remains unknown, this immune-mediated disease is likely triggered by environmental factors in genetically predisposed individuals. I propose that epigenetic mechanisms, which regulate gene expression without affecting the genetic code, mediate the processes that cause MS and that aberrant epigenetic states can be corrected, spearheading the development of alternative therapies. We will exploit the stable and reversible nature of epigenetic marks, in particular DNA methylation, to gain insights into the novel modifiable disease mechanisms by studying the target organ in a way that has not been possible before. This highly ambitious project comprises three synergistic facets formulated in specific aims to: (i) identify epigenetic states that characterize the pathogenesis of MS, (ii) prioritize functional epigenetic states using high-throughput epigenome-screens, and (iii) develop novel approaches for precision medicine based on correcting causal epigenetic states. Our unique MS biobank combined with cutting-edge methodologies to capture pathogenic cells and measure their functional states provides a rational starting point to identify MS targets. I will complement this approach with studies of the functional impact of MS targets using innovative in vitro screens, with the added value of unbiased discovery of robust regulators of specific MS pathways. Finally, my laboratory has extensive experience with animal models of MS and I will utilize these powerful systems to dissect molecular mechanisms of MS targets and test the therapeutic potential of targeted epigenome editing in vivo. Our findings will set the stage for a paradigm-shift in studying and treating chronic inflammatory diseases based on preventing and modulating aggressive immune responses by inducing self-sustained reversal of aberrant epigenetic states.
POLYMER FABRIC, METHOD OF MANUFACTURE AND USE THEREOF

There is provided a polymer fabric that accommodates movement at or adjacent one or more respective surfaces without compromising structural integrity of the or each surface when the polymer fabric is affixed thereon. There is further provided methods of manufacture and application of the polymer fabric. The polymer fabric finds use in applications requiring sealing, containment, protection and insulation.
Quarks fuse to release energy

In nuclear fusion, energy is produced by the rearrangement of protons and neutrons. The discovery of an analogue of this process involving particles called quarks has implications for both nuclear and particle physics. See Letter p.89 The LHCb collaboration at CERN's Large Hadron Collider recently reported the discovery of a doubly charmed baryon with a large binding energy between the two charm quarks inside it. Marek Karliner and Jonathan Rosner report that this strong binding energy allows for a rearrangement of the quarks that releases energy in a quark-level analogue of deuterium–tritium nuclear fusion. They point out that the even larger binding energy between two bottom quarks can also enable such an exothermic rearrangement, with a considerably larger energy release.
Geoquímica e análise multivariada aplicadas na investigação da distribuição dos níveis do flúor das águas subterrâneas e estimativa de riscos de fluorose dentária endêmica no Oeste da Bahia, Brasil

Esta pesquisa pretendeu investigar a influência de fatores geoquímicos na distribuição dos níveis do flúor nas águas do Aquífero Bambuí e seu significado para a saúde humana, no Oeste da Bahia, Brasil. Coletou-se amostras de águas de 76 poços dispostos nas rochas do Grupo Bambuí, em períodos sazonais distintos, para as análises físico-químicas, a leitura de íons principais e do fluoreto (SPADNS). Demonstrou-se que os níveis do fluoreto excederam o limite ótimo local de potabilidade, de 0,8 mg.L-1, para o total de 28% das amostras, com valores do fluoreto distribuídos entre 0,1 e 6,2 mg.L-1. Deve-se evitar o consumo in natura das águas subterrâneas com níveis tóxicos de fluoreto nos municípios do Oeste da Bahia, recomendando-se a aplicação da desfluoretação para que estas águas possam ser consumidas. Além disso, a análise multivariada indicou que o acréscimo em flúor nas águas do Aquífero Bambuí acompanha o aumento do pH e do sódio e a redução dos níveis do cálcio, o que sugeriu que a solubilidade do mineral calcita controlaria a dissolução da fluorita. Esta pesquisa contribuiu para a compreensão da distribuição do flúor nas águas subterrâneas e os seus significados para a saúde bucal e sistêmica no Oeste da Bahia.
MEDiterranean DEvelopment of Support schemes for solar Initiatives and Renewable Energies

The project in brief _x000D_
_x000D_
Solar technology markets have experienced a steady growth in the last decade on the northern shore of the Mediterranean basin while the situation is still at a premature stage in Southern Partner Countries. Notwithstanding the shared political commitment and a common recognition of the huge solar potential of the Mediterranean region, some barriers to solar energy deployment and diffusion persist. These include amongst others weak institutional frameworks, lack of competence of energy practitioners, need of dedicated financial instruments, inadequate perception on the benefits of solar energy investments, subsidized prices of electricity produced by_x000D_
fossil fuel plants and technical issues (such as the quality of equipments and installations). _x000D_
MED-DESIRE main priority is to achieve tangible results on these challenges, removing barriers related to the legal, regulatory, economic and organizational framework of distributed solar energy technologies._x000D_
_x000D_
Specific objective_x000D_
_x000D_
To facilitate the take up of distributed solar energy and energy efficiency in the target regions, by achieving an effective cross-border cooperation and by raising public awareness on the related benefits for the environment and for sustainable local development.
DOOR LOCK

The invention provides a locking apparatus for a door comprising a key wherein the key is engageable with a lock from a first side of the door to enable the door to be unlocked and wherein the card is subsequently only removable from its engagement with the lock at a second side of the door remote from the first side. The sides of a door relevant in describing the invention are the normal front and rear sides of a door as approached by a person walking up to a door rather than any sides which are effectively edges to be retained in a door jamb. The key may be in the form of a card. In a locking apparatus of the invention the key is preferably only removable once engaged in the lock when the door is again locked.
Rapid maxillary expansion versus middle ear tube placement: Comparison of hearing improvements in children with resistance otitis media with effusion

To test the null hypothesis that there are significant differences in hearing improvements of children with resistance otitis media with effusion (OME) who undergo a rapid maxillary expansion (RME) procedure or ventilation tube placement.Forty-two children between 4.5 and 15 years old were divided into three groups: RME, ventilation tube, and control groups. The RME group consisted of 15 children with maxillary constriction and resistance OME that indicated ventilation tube placement. The ventilation tube group consisted of 16 children for whom ventilation tube placement was indicated but no maxillary constriction. The control group consisted of 11 children with no orthodontic and/or rhinologic problems. Hearing thresholds were evaluated with three audiometric records: (1) before RME/ventilation tube placement (T0); (2) after RME/ventilation tube placement (T1), and (3) after an observation period of 10 months (T2). The control group was matched to these periods, except T1.Hearing thresholds decreased significantly in both the RME and ventilation tube groups (P < .001). Hearing thresholds decreased approximately 15 and 17 decibels in the RME and ventilation tube groups, respectively, but differences in improvements were insignificant between the two study groups (P > .05). Slight changes were observed in the control groups.The null hypothesis was rejected. RME showed similar effects as ventilation tube placement for release of otitis media and improvement of hearing thresholds levels. RME should be preferred as a first treatment option for children with maxillary constriction and resistance OME.
PROCESSES AND METHODS FOR EXTRACTION AND PURIFICATION OF LUTEIN FROM MARIGOLD ESTERS

A process is disclosed for simultaneously extracting, saponifying, and isolating lutein without the use of harmful organic solvents. In one embodiment the method includes (a) dispersing Marigold oleoresin in an alkane hydrocarbon alkanol solution, (b) adding a potassium hydroxide to the Marigold oleoresin and alkane hydrocarbon alkanol solution to form a homogenous solution of Marigold oleoresin, (c) refluxing the homogeneous solution until ester hydrolysis of the Marigold oleoresin is completed, (d) cooling the homogeneous solution and allowing it to settle until lutein crystals are formed and (e) washing the lutein crystals with methanol-hexane solution to separate and filter them from the solvents.
DOOR ARRANGEMENT

The present invention relates to an arrangement pertaining to a revolving door for installing in a building (1). The arrangement comprises partly a rotor (10) with a two-winged door arrangement adapted to regulated rotation about a vertical rotation axis (20) in a passage space (30), which rotor has at least one openable portion (11) allowing passage through the wings in an evacuation situation and has at the free end of each wing an arcuate door panel (12) with its external convex surface (13) at a substantially constant radial distance r from the rotation axis (20) of the rotor; and partly two wall sections (40) which delineate said passage space, are arranged at a distance from one another and each extend from their respective side of a first entrance aperture (50) which they jointly delineate to their respective side of a second entrance aperture (50') which they jointly delineate. Openable evacuation portions (41, 41') are further disposed in at least one of the wall sections (40), allowing passage through the passage space (30) in an evacuation situation even if the entrance apertures (50, 50') are closed by the rotor (10), and at least one of said openable evacuation portions (41, 41') is disposed in a portion of the wall section 40 which is rectilinear in horizontal cross-section.
Remediation of soils contaminated with chromium using citric and hydrochloric acids: the role of chromium fractionation in chromium leaching

Acid washing is a common method for soil remediation, but is not always efficient for chromium-contaminated soil. Both soil particle size and the forms of chromium existing in the soil affect the efficiency of soil washing. Laboratory batch and column dissolution experiments were conducted to determine the efficiencies of citric and hydrochloric acids as agents to extract chromium from soils contaminated with chromium. The effects of soil particle size and chromium fractionation on Cr leaching were also investigated. About 90% of chromium in the studied soil existed either in residual form or bound to iron and manganese oxides, and Cr fraction distributions were similar for all soil particle sizes. Almost all exchangeable and carbonate-bound chromium was removed by washing once with 0.5 M HCl, whereas organic chromium was more effectively removed by washing with citric acid rather than with HCl solution of the same concentration. For chromium fractions that were either bound to Fe-Mn oxides or existed as residual forms, the efficiencies of acid washing were usually 20% or less, except for 0.5 M HCl solution, which had much higher efficiencies. Separation of the soil sample by particle size before the separate washing of the soil fractions had little improvement on the chromium removal.
Initial singularity and pure geometric field theories

In the present article we use a modified version of the geodesic equation, together with a modified version of the Raychaudhuri equation, to study initial singularities. These modified equations are used to account for the effect of the spin-torsion interaction on the existence of initial singularities in cosmological models. Such models are the results of solutions of the field equations of a class of field theories termed pure geometric. The geometric structure used in this study is an absolute parallelism structure satisfying the cosmological principle. It is shown that the existence of initial singularities is subject to some mathematical (geometric) conditions. The scheme suggested for this study can be easily generalized.
The synthesis of compensation circuits of parasitic capacitances of the output circuit of classical broadband amplifiers of signal and telecommunications systems

The paper considers the conditions of synthesis of a special compensation circuit (CC) of parasitic capacitance connected with an output of classic transistor stage (TS) from the common ground of the theory of automatic control systems. The purpose of CC is to extend the frequency range of TS, especially at high-resistance loads, including active ones. It is shown that the connected CC should contain a differentiating link. The analysis of scheme stability of a broadband amplifier (BA) with CC is carried out. The analytical expressions are obtained to estimate maximum advantage on bandwidth and transient time in classic transistor stages (circuits with common-emitter, common base). Three main options of practical implementation of CC in the basis of non-inverting voltage/current followers are considered.
Continuous hazardous water pollutants sensing in the environment

CoPs combines the expertise of the 3 industry partners – ground-breaking electrochemical sensors developed by IPM, miniaturised electronics customised by PAL and CAU’s geo-monitoring hardware and software – and is expected to bring economic, social and environmental impacts, including towards achieving UN SDGs and EU policy.
Pesticide and nitrate pollution in fresh waters pose a significant risk to public health and the environment. Exposure to pesticides can lead to several cancer types or Parkinson’s disease, while nitrate can result in “Blue Baby Syndrome” and cause eutrophication. According to latest estimates, getting sick from drinking tap water in Europe had a societal cost of €220 million. Meanwhile, inefficient water monitoring based on sampling and lab analyses does not provide early alerts. Water suppliers need to meet EU monitoring requirements and react instantly with contamination treatment protocols, protect water supplies and avoid economic losses through shutdowns.
Our innovative solution rapidly detects specific water pollutants and transmit real-time data on contaminant levels and movements in natural water systems before they could reach water infrastructures and consumers. It saves both time and costs (by at least 40%), it vastly improves data quality and quantity, and it provides a data analysis and hazardous pollutants alert service to monitoring agencies.
Our goal is to mature, scale-up and demonstrate the production of the CoPs sensor platform for continuous in-situ water monitoring, targeting water suppliers as initial clients, and with the potential to create new markets within the agriculture and private well owner segments.
A successful CoPs project will allow us to create measurable impacts on our companies, quantified as accumulated revenue of €217m in five years (2021-2025), equal to accumulated operating profit of €86.05m, creating 101 full time employments in our value chain, and generating €21.83m in reduced costs for our end-users
Polysaccharide peptides from Coriolus versicolor competitively inhibit tolbutamide 4-hydroxylation in specific human CYP2C9 isoform and pooled human liver microsomes

Polysaccharide peptide (PSP), isolated from COV-1 strain of Coriolus versicolor, is commonly used as an adjunct in cancer chemotherapy in China. Previous studies have shown that PSP decreased antipyrine clearance and inhibited CYP2C11-mediated tolbutamide 4-hydroxylation in the rat both in vitro and in vivo. In this study, the effects of water extractable fraction of PSP on tolbutamide 4-hydroxylation was investigated in pooled human liver microsomes and in specific human CYP2C9 isoform. PSP (2.5-20μM) dose-dependently decreased the biotransformation of tolbutamide to 4-hydroxy-tolbutamide. Enzyme kinetics studies showed inhibition of tolbutamide 4-hydroxylase activity was competitive and concentration-dependent. In pooled human liver microsomes, PSP had a K(i) value of 14.2μM compared to sulfaphenazole, a human CYP2C9 inhibitor, showed a K(i) value of 0.32μM. In human CYP2C9 isoform, the K(i) value of PSP was 29.5μM and the K(i) value of sulfaphenazole was 0.04μM. This study demonstrated that PSP can competitively inhibit tolbutamide 4-hydroxylation in both pooled human liver microsomes and specific human CYP2C9 in vitro. This study compliments previous findings in the rat that PSP can inhibit human tolbutamide 4-hydroxylase, but the relatively high K(i) values in human CYP2C9 would suggest a low potential for PSP to cause herb-drug interaction.
Semi-automatic bailer plug

A semi-automatic boiler plug assembly having a mounting plate with a central hole aligned with a bailer hole on a boat transom is described. Attached to the mounting plate is a cylinder and piston therein made of a resilient material which seats in the central hole of the mounting plate in a closed position. Two arms extending to either side of the piston, and through slots on opposite sides of the cylinder, guide the piston in its travel back and forward in the cylinder. Immediately behind the piston is a spring to bias the piston forward in the cylinder toward the closed position. On the outside of the cylinder are two hinge plates attached to the piston by guide arms and by hinge pins that pass through a hole in the hinge plates and into the piston guide arms. Formed onto the outboard side of the hinge plates are hollow chambers which form floats. Across the rear edge and placed perpendicular to the hinge plates, and extending beyond the two hinge plates to the outermost face of each float is a coupling plate. The coupling plate joins together both hinge plates and floats to comprise a hinged float assembly which pivots in unison to open or close the bailer hole. The outer face of the coupling plate is fluted, serrated or otherwise deformed to create a rough surface to assist the automatic triggering of the spring-biased bail plug when the boat transom is placed in the water.