SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Regulation of single hematopoietic stem cells by intake of vitamin a

Quiescence preserves the self-renewal capacity and the long-term function of hematopoietic stem cells (HSCs). The regulators of this dormant state include intrinsic pathways and soluble components in the bone marrow niche. Dysregulation of this process is poorly defined and might cause aberrant hematopoiesis. In my previous work, we defined the molecular landscape of HSCs by applying state of the art DNA-methylome, RNA-seq and proteome analyses, and found vitamin A/retinoic acid (RA)-induced signaling predominantly enriched in HSCs (Cabezas-Wallscheid et al., Cell Stem Cell 2014). Intriguingly, we observed that mice fed with a vitamin A-free diet exhibited a robust loss of HSCs (Cabezas-Wallscheid et al., Cell 2017). Treatment of mice with a RA agonist preserved HSC quiescence in stress-activated conditions, indicating that the balance between HSC maintenance and differentiation is tightly regulated by vitamin A signaling. 

However, we are only beginning to understand the mechanisms how vitamin A regulates HSC fate. Since treatment of vitamin A deficiency currently shows extremely low therapeutic success, novel insights into the role of HSCs in the development of the disease will be of enormous therapeutic value.
METHODS OF MEASURING GENE EXPRESSION USING WAX-EMBEDDED TISSUE SPECIMENS

This invention provides methods for the isolation of complete representation of cellular messenger ribonucleic acid from wax-embedded tissue samples. Expression of genes of interest can thus be fortuitously determined and cDNA probes can be readily developed.
Archaeology and development at loggerheads: But should they be?

In a recent South African Archaeological Bulletin (vol. 66, no. 194), two articles on the concerns against coal mining at Vele near Mapungubwewere published (Meskell 2011; Swanepoel 2011). This discussion forum article attempts to respond to some of the points raised in the article by Natalie Swanepoel. More importantly, I aim to take the discussion forward by recommending that we bridge the polarity that exists between archaeologists and those who can collectively be called developers. The latter are considered destructive in their approach, which brings them at loggerheads with the former. Without finding a common ground between us and the developers, we shall remain at loggerheads, and our own purposes will not be served. Some in the discipline might beg to differ. However, I will submit that this is the debate that we must have. I begin by presenting a general perspective I have of the conflict between archaeologists and developers. And in doing so, I argue that they win the support 'race' over us because they play their cards very well. Rather than 'shout' at the outside world, I further argue that we need to undertake an introspective stance and ask to what extent are we cleaning our discipline so that it has the human face developers claim to have. Some of the problems are of our own doing, and until we own up and attend to the problems within archaeology, we would be failing ourselves.
The Design and Implementation of the Real Estate Intermediary Management Information System Based on ASP.NET Technology

Against a real estate intermediary status of the company's business, system design in general to adopt a Bowser / Server(referred to as B / S) of the three-tier structure model, select the Visual Studio 2005 development environment, using ASP.NET 2.0 development techniques, first using UML Unified Modeling Language, according to system requirements for the overall design, arrive at the system needs to achieve the availability of information management, customer information management, franchise information management, employee information management, and issue a press release to gather feedback on the user rights to be divided, features such as password changes back, and then use the C # language service code, SQL Server 2005 database development system to achieve real-estate agents information management system.
Electret condenser microphone

An object of the present invention is to provide a digital-output electret condenser microphone capable of being soldered on a wiring substrate of an apparatus by using a reflow furnace. An electret condenser microphone according to the present invention has an electret polymer film and a spacer that are formed of a heat-resistant material. Sound apertures are provided in a front panel of the electrically conductive capsule and/or the wiring substrate. Provided on the surface exposed in the open end of the electrically conductive capsule are multiple terminals, including at least a power supply terminal, a digital signal output terminal, and a clock input terminal. The terminals are protruded outward beyond a caulked part at the open end of the electrically conductive capsule.
iHERITAGE: ICT Mediterranean platform for UNESCO cultural heritage

The Mediterranean UNESCO cultural heritage needs new techniques to improve its level of interpretation, taking advantage of new technologies and commercialising the latest research results. In this regard, iHERITAGE will provide new solutions through an innovation-driven growth process to promote cross-border technological transfer, Living Labs, industry-academia collaboration and the creation of spin-offs and new products, using the latest Information and Communication Technologies (ICT): Augmented Reality (AR), Virtual Reality (VR) and Mixed Reality (MR).
The project will address socio-economic challenges at cross-border level through the active involvement of young people, women and NEETs who will take part in the Living Labs, training courses, and the creation of spin-offs, thus contributing to increase employment opportunities and foster innovation. The project will support collaborations among universities, SMEs, start-ups and spin-offs devoted to the creation of AR/VR/MR products. Eventually, iHERITAGE will improve access to UNESCO cultural heritage, on site and off site, and will contribute to the establishment of the Regional Centre for Safeguarding and Valorisation of Mediterranean Intangible Cultural Heritage, to be recognized under Category 2 of UNESCO.
ON ELASTIC STRESS WAVES IN AN IMPACTED PLATE

Elastic stress wave theory is developed and the stress waves in the impacted plate are examined in the paper. Generalized linear elasticity is adopted where the couple stress and curvature tensor are both deviatoric tensors and they meet a linear constitutive relation. It is found that there exist volumetric, rotational, and deviatoric waves in the generalized elastic solids. However, for macro-scale elastic solids only two wave modes, namely a volumetric wave and a deviatoric wave should be taken into account. Wave motion in plate impact tests is studied that a volumetric wave and a deviatoric wave are proposed. A set of exact solutions is attained for elastic stress waves in an impact plate. Excitation of stress waves at impact surface and reflection at free surface are formulated. Propagation of stress waves in the plate is analyzed in the waveforms. The predicted stress history in a ceramic plate under impact is agreed very well with the experiment measurement.
Luminescent Benzoquinolate-Isocyanide Platinum(II) Complexes: Effect of Pt⋅⋅⋅Pt and π⋅⋅⋅π Interactions on their Photophysical Properties

The neutral compounds [Pt(bzq)(CN)(CNR)] (R = tBu (1), Xyl (2), 2-Np (3); bzq = benzoquinolate, Xyl = 2,6-dimethylphenyl, 2-Np = 2-napthyl) were isolated as the pure isomers with a trans-C(bzq),CNR configuration, as confirmed by (13)C{(1)H} NMR spectroscopy in the isotopically marked [Pt(bzq)((13)CN)(CNR)] (R = tBu (1'), Xyl (2'), 2-Np (3')) derivatives (δ(13)C(CN) ≈ 110 ppm; (1) J(Pt,(13)C) ≈ 1425 Hz]. By contrast, complex [Pt(bzq)(C≡CPh)(CNXyl)] (4) with a trans-N(bzq),CNR configuration, has been selectively isolated from [Pt(bzq)Cl(CNXyl)] (trans-N(bzq),CNR) using Sonogashira conditions. X-ray diffraction studies reveal that while 1 adopts a columnar-stacked chain structure with Pt-Pt distances of 3.371(1) Å and significant π⋅⋅⋅π interactions (3.262 Å), complex 2 forms dimers supported only by short Pt⋅⋅⋅Pt (3.370(1) Å) interactions. In complex 4 the packing is directed by weak bzq⋅⋅⋅Xyl and bzq⋅⋅⋅C≡E (C, N) interactions. In solid state at room temperature, compounds 1 and 2 both show a bright red emission (ϕ = 42.1% 1, 57.6% 2). Luminescence properties in the solid state at 77 K and concentration-dependent emission studies in CH(2)Cl(2) at 298 K and at 77 K are also reported for 1-4.
Single-case study in rehabilitation with SaM method (Sense and Mind): a proposal and analysis

The aim of the present case report is to describe a new rehabilitation approach for traumatic brain injury (TBI).TBI is a heterogeneous disorder that could be associated with cognitive and behavioral impairments. The clinical complexity of TBI patients requires a specialized and integrated approach that involves several rehabilitation experts (Mazzucchi in La riabilitazione neuropsicologica, Elsevier-Masson, Milan, 2012). SaM method (SaMM) (Risoli in La riabilitazione spaziale, Carocci Faber, Rome, 2013) is a new rehabilitation approach based on "embodied cognition" theory (Gallese and Lakoff in Cogn Neuropsychol 22(3):455-479, 2005) and has the aim to improve spatial abilities through structured body exercises.The patient was a 35-year-old male who had TBI 9 months before. The patient was evaluated, before and after the treatment, with neuropsychological tests (Rey Test copy and reproduction, Elithorn Test, Trail Making Test, Rey Auditory Verbal Learning Test), Lawton Index for IADL, level of cognitive functioning, and a qualitative process-oriented assessment with SaMM exercises. The patient was treated with SaMM for 4 months, three times a week.Several of the executed assessments showed an improvement after SaMM treatment. The patient also reported amelioration in some daily activities such as swimming and using phone and money.Further investigations are necessary, but the SaMM appeared to be a useful complementary restitutive approach for TBI patients.
Year-round haul-out behaviour of male walruses Odobenus rosmarus in the Northern Barents Sea

Haul-out behaviour is a central component in the life history of pinnipeds; seasonal patterns in this behaviour reveal insights into annual energy budgets and basic biology. In this study, custom-designed satellite-relay data loggers were deployed on 17 male walruses Odobenus rosmarus in Svalbard, Norway. Individual animals transmitted data for a mean ± SD of 255 ± 132 d (range = 54�471 d), performing on average 110 ± 65 haul-out events (range = 30�247 events); the data records for 5 animals were longer than 1 yr. Clear seasonal patterns occurred in the percent- age of time hauled out and average haul-out duration; both variables reached maxima in summer and minima in winter. Time between haul-out events reached a maximum during the breeding season in winter. The walruses moved away from shore-based haul-out sites and onto sea ice in November and December, and returned to land again in June. Analyses using generalized addi- tive mixed models and Cox proportional hazard models demonstrated that wind chill and time in the water prior to a haul-out event had the largest impacts on haul-out probability and duration, although wind chill had little impact during the summer when temperatures were not challenging, and also had reduced influence during the breeding period. Long periods at sea were followed by long periods hauled out, resulting in a relatively constant proportion of time spent hauled out over time scales of weeks. Our results indicate the importance of breeding in dictating male haul-out patterns during winter, and provide a baseline to assess impacts of future climate change.
Cache alternatives concerning cache coherence in NoC-based MPSoC platform

The cache coherence problem is an open issue on MPSoC environments. Some solutions have been purposed to solve it. However, few have been address the problem considering Networks-on-Chip as interconnection mechanism. The directory solution is the most feasible solution for cache coherence problem in such systems. This paper present two cache alternatives concerning cache coherence in NoC based MPSoC systems. The first alternative is the discard of the data cache eliminating the cache coherence problem. The second alternative is to use a read-only data cache and hence, eliminate the writing operations that create the cache coherence problem. The results show that these approaches generate very different amounts of NoC traffic and response for memory accesses.
The wolves of the north : a warrior of Rome novel

Experience all the action of Rome with Harry's latest epic. AD263 - barbarian invasions and violent uprisings threaten to tear apart the Imperium of Rome. In the north, the tribes are increasingly bold in their raids on the Imperium - their savagery unlike anything Rome has known before. Ballista must undertake his most treacherous journey yet - a covert attempt to turn the barbarians of the steppe against each other. He must face the Heruli - the most bizarre and brutal of all the nomad tribes - the Eaters of Flesh, the Wolves of the North. As Ballista and his retinue make their journey, someone - or something - is hunting them, picking them off one by one, and leaving a trail of terror and mutilated corpses. Ballista is in a strange land, among strange people, but is it possible that the greatest threat may come from within his own familia?
CONECTOR PARA BARRAS PERFILADAS EN FORMA DE ACANALADURAS Y DISPOSICION DE CONEXION.

Conector (3, 3') para barras perfiladas en forma de acanaladuras (1, 2), en particular para la formación de instalaciones sanitarias, con dos placas (6, 7) opuestas una a otra, que están conectadas una con otra mediante al menos un medio de fijación (9) y una pieza intermedia (8, 8') y que pueden fijarse por apriete en una barra perfilada en forma de acanaladura (1, 2), estando formados salientes (61, 71) en los bordes exteriores de las placas, que pueden hacerse encajar en ranuras (4) realizadas en las barras perfiladas (1, 2), estando dispuesto al menos un distanciador (15) en la pieza intermedia (8, 8') entre los bordes exteriores de las placas (6, 7), que puede insertarse entre dos tramos de pared (5) opuestos de la barra perfilada (1, 2) para apoyar una barra perfilada en forma de acanaladura (1, 2), caracterizado porque el distanciador (15, 15') está fijado mediante una conexión por pinza de cocodrilo o una conexión por inserción de forma separable en la pieza intermedia (8, 8').
Independence of alpha and beta diversities

Denny, M., and S. Gaines. 2000. Chance in biology: using probability to explore nature. Princeton University Press, Princeton, New Jersey, USA. Jost, L. 2006. Entropy and diversity. Oikos 113:363-375. Jost, L. 2007. Partitioning diversity into independent alpha and beta components. Ecology 88:2427-2439. Quinn, G. P., and M. J. Keough. 2002. Experimental design and data analysis for biologists. Cambridge University Press, New York, New York, USA. Ricotta, C. 2005. On hierarchical diversity decomposition. Journal of Vegetation Science 16:223-226. Ricotta, C. 2008. Computing additive beta-diversity from presence and absence scores: a critique and alternative parameters. Theoretical Population Biology 73:244-249. Sokal, R. R., and F. J. Rohlf. 1995. Biometry. Third edition. Freeman and Company, New York, New York, USA. Tijms, H. 2004. Understanding probability: chance rules in everyday life. Cambridge University Press, Cambridge, UK. Wilson, M. V., and A. Shmida. 1984. Measuring beta diversity with presence-absence data. Journal of Ecology 72:1055 1064.
Flynano - electric aircraft feasibility verification

The innovation supports the EU’s efforts for sustainable aviation. High-tech eco-innovative electric airplane FlyNano is at TRL 7 and soon to be finished to mass-production. The solution is patented. FlyNano is environmentally and noise friendly plane which uses watercourses as runway. The plane has standard controls and normal airplane’s flying characteristics. The exceptional design of FlyNano includes advanced carbon fibre structure; patented detachable, one-piece boxwing invention, and a unique lightweight electrical powertrain has the world’s best power to weight ratio.
The impacts are emissions reduction, safety, noise reduction, workplaces and new business. The solution is unique. Clear business opportunity and customer demand have been detected market tests. The first 10 FlyNanos have been presold and the concept launch lead to 50 M viewers in various media. 
Fly Nano Ltd (established at 2010) has highly talented team of 12 professionals with the key knowledge for the development and commercialisation of the innovation. The expected growth potential for the next five years is 100 M€ yearly revenue, 50 new workplaces, 5 new patents, 1500 FlyNanos sold and 500 powerlines sold.
This feasibility study aims to verify the practical and economic viability of the innovation. The expected outcome of this project is a plan for global commercialisation of FlyNano.
Exchange Rate, Income Distribution and Technical Change in a Balance-of-Payments Constrained Growth Model

This article develops a formal model that accounts for the net effect of an exchange rate devaluation on the long-term balance-of-payments constrained growth rate. Such a model investigates how a currency devaluation impacts on the home country non-price competitiveness via changes in income distribution and the rate of technological innovation. The model is built upon two plausible hypotheses. First, it is assumed that the rate of technological innovation is directly related to the income elasticity of demand for exports and inversely related to the income elasticity of demand for imports. Second, it is assumed that a redistribution of income between labor and capital has an ambiguous direct impact on the income elasticities ratio. The model shows that the net impact of a currency devaluation on growth can go either way depending on the institutional framework of the economy.
Study of the atom-phonon coupling model for (SC) partition function: first order phase transition for an infinite linear chain

In spin-conversion (SC) compounds containing molecules organized around an iron (II) ion the fundamental level of the ion is low spin (LS), S = 0, and its first excited one is high spin (HS), S = 2. This energy diagram is due to the ligands field interaction on 3d electrons and to the spin pairing energy. Heating the compound increases the magnetic susceptibility which corresponds to a change of populations of both levels and consequently a change of spin value of the molecules. This mechanism, called spin conversion (SC), can be accompagnied by thermal hysteresis observed by studying magnetic susceptibility or high spin fraction. In that case one considers that the (SC) takes place through a first-order phase transition due to intermolecular interactions. In the atom-phonon coupling model the molecules are considered as two-level systems, or two-level atoms, and it is assumed that the elastic force constant value of the spring which links two atoms first neighbours is depending on the electronic states of both atoms. In this study we calculate the partition function of a linear chain of N atoms (N ≤ 16) and we describe the role of phonons and that of the parameter Δ which corresponds to the distance in energy between both levels. The chain free-energy function is F
 atph
 . We introduce for the chain a free-energy function defined by the set (F
 HS
 , F
 LS
 , F
 barr
 ) and we show that F
 atph
 tends towards the previous set when N → ∞. The previous set allows to describe a first order phase transition between a (LS) phase and a (HS) one. At the crossing point between the function F
 LS
 and F
 HS
 , and around this point, there is an intermediate free-energy barrier which prevents the chain to change phase which can lead to thermal hysteresis. The energy gap between the free-energy function F
 atph
 and that defined by the set (F
 HS
 , F
 LS
 , F
 barr
 ) is small. So we can expect that a nanoparticule takes for free-energy function that defined by the set and then displays a thermal hysteresis.
Liquid-phase hydrogenation of benzaldehyde over Pd-Ru/C catalysts: Synergistic effect between supported metals

Abstract Bimetallic Pd-Ru/C catalysts prepared with different carbon supports were shown to be much more active in the liquid-phase hydrogenation of benzaldehyde in comparison with their monometallic analogs. In the case of systems based on nanoglobular carbon, the synergistic effect manifested itself as an increased selectivity for benzyl alcohol (86–90%) at a complete conversion of benzaldehyde, whereas the catalysts containing carbon nanotubes were highly active in hydrogenolysis of the C O bonds, which caused an increased yield of toluene (up to 56%). The synergistic effect between palladium and ruthenium in the reaction under study can be related to the changes in the electronic and dispersion state of the supported metals upon interaction with each other and formation of Pd-Ru alloy. In terms of the electronic factor, the enhanced catalytic performance of bimetallic systems can be a result of facilitation of electrophilic activation of the C O bond in benzaldehyde owing to an increased fraction of the electron-deficient palladium species. The nature of carbon support was shown to affect the electronic state of supported metals and thus catalytic properties of bimetallic Pd-Ru/C systems.
Atomic structures and electronic properties of Ni or N modified Cu/diamond interface

The interfacial stability of copper/diamond directly affects its mechanical properties and thermal conductivity. The atomic structures and electronic properties of Cu/diamond and Cu/X/diamond interfaces have been identified to investigate the effect of interfacial additive X (X = Ni or N) on the low-index interfacial adhesion of copper/diamond composites. For unmodified composites, the interfacial stability decreases in the order of Cu(0 0 1)/diamond(0 0 1) > Cu(1 1 1)/diamond(1 1 1) > Cu(0 1 1)/diamond(0 1 1). The metallic interfacial additive Ni is found to enhance the Cu(0 1 1)/diamond(0 1 1) interfacial stability and exchange the interfacial stability sequence of (0 1 1) and (1 1 1) composites. The nonmetallic element N will promote the stability of Cu(1 1 1)/diamond(1 1 1) but not alter the stability order of the composites at different interfaces. To explain the origin of interfacial stability, a series of analyses on atomic structures and electronic properties have been carried out, including the identification of the type of formed interfacial boundaries, the measurement of interfacial bond lengths, and the calculations of density of states, bond populations, and atomic charge. The stability of the interface is found to be related to the type of formed interfacial boundary and bond, the interfacial bond populations, and the interfacial bond numbers. The layer-projected density of states reveals that all of the considered interfaces exhibit metal characteristics. The interfacial Ni additive is found to be an electron donor contributing the electrons to its bonded Cu and C atoms while the interfacial N atom is an electron acceptor where it mainly accepts the electrons from its bonded Cu and C.