SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Promoting Safety Environment for School Sports

The purpose of this study was to examine the safety environment under which school sports programme is organized in Nigeria schools. The paper noted that poor environment under which PES is administered militated against smooth attainment of physical education and sports in schools. In this regard the paper explored how to overcome these shortcomings so as to promote safety. Essentially the area explored is in provision of facility and equipment and the role of sports personnel. These are major factors in promoting safety in school sports. It is also in this vein the strategy likely to promote sports safety were proffered.
Ser-Col; from finger to laboratory; personalized and automated serum collection for laboratory diagnostics

95% of blood collected via venipuncture is not used for diagnostic measurements, and needs to be disposed as biohazardous waste by incineration, which is incredibly wasteful and taxing on our environment. In Europe, there is an urgent need for innovative approaches that engage vulnerable groups and increase access to infectious disease testing by breaking-down social and logistic barriers to healthcare. The decentralization of healthcare have created a need for a simple, safe, standardized and painless collection of serum specimens. The Ser-Col® is a novel serum separation device that simplifies and combines both blood collection and serum separation.  With a few drops of blood from a finger stick, serum can be collected which is stable for several months prior to analysis of clinically relevant serum parameters, and thereby reducing biohazardous waste production by 50%. Ser-Col simplifies and reduces the cost of serum sampling by replacing the blood tube, trained personnel, cold storage, and centrifuge with a reliable and easy to use device that links target population to centralized diagnostics laboratories, ultimately leading to the long-term reduction of the burden of infectious diseases. The SCAUT consortium will scale up manufacturing to deliver a market ready version of the Ser-Col and validate its clinical performance against existing standards. To ensure market uptake the consortium will develop an automated serum processing platform for optimal compatibility with exciting laboratory diagnostic equipment and facilitate adoption of Ser-Col by healthcare professionals. This will accelerate commercialization, attract investors and to establish industry partnerships required to realize the full potential of the technology. The SCAUT project seeks to obtain €3 million to finalize the analytical and clinical validation and go-to-market of the Ser-Col® device. The estimated cumulative profit is €463.813 in 2023 increasing towards €18 million in 2027.
Revitalizing the clinical potential of type i ifns in fighting influenza a virus infections with actaferon.

Based on their antiviral and antitumor effect, type I interferons (IFNs) were believed to be the miracle drug to tackle viruses and cancer. However, clinical IFN applications remained limited due to severe side effects resulting from widespread cellular sensitivity to IFN, which limits the administrable doses. Hence, the drug concentration at the desired infection or tumor site is often too low to be fully therapeutic efficient. AcTaferon (Activated-by-Targeting interferon), co-developed by Prof. Uzé, circumvents these obstacles. By fusing an IFN mutant with strongly reduced receptor binding affinity to a targeting moiety that recognizes a surface marker on specific cells, AcTaferon remains inactive “en route” through the body and unveils its biological activity only on specific target cells. Robust tumor regression without side effects and preliminary antiviral effects underscore the huge clinical potential of AcTaferon to fight cancer and viral diseases. By combining the AcTaferon and influenza expertise of Prof. Uzé and Prof. Saelens, respectively, this interdisciplinary project offers the opportunity to broaden the innovative AcTaferon therapeutic strategy from the cancer to the viral infection field. Influenza A was selected as a pilot target as seasonal influenza A epidemics and occasional pandemics remain a serious health threat causing substantial morbidity and mortality. Influenza A-targeted AcTaferons will be developed and analyzed in relevant in vitro and in vivo models. Eventually, all knowledge will be transferred to Orionis, a company that will implement the AcTaferon technology to develop novel drugs. My background on the intracellular processes that negatively regulate cytokine receptors and hence influence the cellular sensitivity to a (therapeutic) cytokine is an asset to this project. I will be able to extend my fundamental research experience with applied cytokine research, which may extend into a new academic or industrial research pipeline.
Fatigue modelling and fast testing methodologies to optimize part design and to boost lightweight materials deployment in chassis parts

Fatigue4Light project aims to investigate lightweight solutions adapted to the chassis part of EV to reach a 24-30% weight reduction. This will give a 12-15% weight saving from structural vehicle weight, and also increase EV safety due to reduced sprung mass. Solutions will be based on the introduction of especially developed material solutions with high fatigue performance (AHSS, stainless steel, Al alloys and hybrid metal-FRP materials), the development of new computer modelling with high fatigue prediction accuracy and new experimental methodologies that reduce the testing time. Sustainability of the proposed solutions will be continuously considered along project through an eco-design general approach. Environmental assessments through LCA, affordability based in LCC as well as social inclusion thanks to the recovery of CRMs from alternative waste streams will allow endowing Fatigue4Light into a novelty circular dimension. Attention will be given to manufacturing processes (cutting and welding) to improve the knowledge on their effect to the overall fatigue performance of chassis components. Six lab scale and industrial demonstrators will be defined to validate the proposed solutions. The fatigue model will be verified on demonstrators and then used in a virtual testing process to assess the weight reduction potential of the proposed materials, together with a redesign process oriented to lightweight the components while ensuring structural integrity. The project will reduce lead times to market due to the developed model and advanced fatigue testing methodologies and standardization will be followed. The final outcome is to give modelling and experimental tools for the lightweighting process on chassis parts subjected to fatigue. Clear and practical guidelines will be established with respect to different factors: eco design with proposed materials, advanced modelling approaches and the influence of forming processes on part performance.
Identifying predictors of risk and resilience for poor neuropsychological outcome following childhood brain insults (probit)

The impact of insults to the developing brain upon cognition and behaviour has far-reaching consequences for the child, their family, education and health care systems, and government expenditure. Many variables (illness, environmental) contribute to different outcomes following similar insults, and they exert their influence via the child’s developing brain. Predicting which child will recover from early brain insult and identifying those at risk of poor outcome represents a major challenge, with significant health economic implications. An unexplored question is whether direct measurement of the structure and function of the developing brain can improve our ability to predict outcomes in the long-term. Thus, PROBIt aims to assess the utility of brain imaging biomarkers to predict individual neuropsychological and neurobehavioural outcomes following paediatric brain injury, and to identify those factors that combine optimally to classify outcomes. The proposal adopts an unorthodox approach of combining heterogeneous injury groups to explore the structural and functional consequences of perturbing developing brain networks. PROBIt integrates data from clinically relevant paediatric cognitive and behavioural assessment, neuroimaging and computational modelling in large cohorts of children with brain insults. Multivariate pattern analysis will be used to train a statistical classifier to reliably predict individual child outcomes across three core domains: achievement, behaviour and cognitive ability. PROBIt significantly advances our understanding of features that confer risk and resilience to different neurodevelopmental outcomes and has important implications for clinical diagnosis and rehabilitation of children with early brain insults.
Industrial biotechnology innovation and synthetic biology accelerator

The overarching aim of IBISBA 1.0 is to support and accelerate the uptake of industrial biotechnology as a key enabling technology for advanced manufacturing. To do this, IBISBA 1.0 will provide a distributed network of research infrastructure facilities to promote R&D in bioprocess development and support this bioeconomy KET. The facilities cover a variety of experimental and in silico operations and disciplines, and together represent the R&D continuum in the range TRL2 to 6 needed to build quality biomanufacturing processes for industrialization. In addition to hardware, IBISBA 1.0 will operate an ICT platform, linking all project events occurring on facilities, and external data repositories, and provide users with end-to-end project management and access to a wide variety of research assets. Together, these developments create the basis for a future pan-European research infrastructure for industrial biotechnology, the feasibility of which will be established during the project. Through IBISBA 1.0, the participant facilities will be opened for transnational access, thus providing cutting edge technologies to a cross section of Europe’s researchers, including early career stage scientists. Users and facility operators will receive remote and on-site training, and immersion in the hallmark multidisciplinary environment of IBISBA 1.0. Transnational access will be facilitated by an ambition outreach plan that will provide users, including SMEs and other industry players, with complete information about service offers, but also insight into the potentiality of IPR held by IBISBA 1.0 partners and the opportunities for innovation. Interoperability will be a focus of considerable attention, with actions directed towards harmonization and the implementation of repeatable working practices that integrate experimentation with data analysis, and data management, thus providing the basis for the sharing and reuse of data assets in a framework of Open Science.
ILLUMINATION BARRICADE TAPE AND POWER SUPPLY UNITS FOR ILLUMINATING SAME

Equipment for entering and exiting boats is addressed. Generally, the equipment is in the form of "divers' doors" for inflatable or similar boats. However, unlike existing inflatable doors, the doors discussed herein need not necessarily inflate. Instead, they may be formed as flaps moveable between closed and open positions. Ramped rub strakes or other aspects of the boats may assist in diverting water away from any gaps present when the flaps are closed but the boats are travelling at significant speeds.
Mental Health and The Built Environment

Chapter 1 Introduction and Background: What is mental illness? What is meant by planned Mental illness and the environment: early studies Recurrent methodological issues. Chapter 2 Classical Environmental Stressors: What is environmental stress? Air pollution The seasons, heat, wind and weather Noise New evidence on noise: the effects from road traffic Summary. Chapter 3 Social Environmental Stressors: What is a social environmental stressor? Crowding Crime, fear and the environment Summary and refinements to the stress model. Chapter 4 Social Support and the Planned Environment: Introduction Social networks, social support and mental health Social factors affecting neighbouring behaviour The physical environment and social support Conclusion: the ideal neighbour and the ideal neighbourhood. Chapter 5 The Environment as Symbol and the Example of the High-Rise: Introduction Labelling Aspiration achievement discrepancies The example of the high-rise flat. Chapter 6 The Planning Process: Introduction Relocation and slum-clearance Resident participation in the planning process Case study: demolition!. Chapter 7 Improving Mental Health Through the Environment - A Case Study: Design and methodology About the estate The intervention The impact of the changes The impact on residents' mental health Summary. Chapter 8 Mental Illness and the Planned Environment: Is there a causal relationship between mental illness and the planned environment? Broader implications.
Educational mismatch and unemployment scarring

Purpose – The purpose of this paper is to investigate educational mismatch and its interrelationships with unemployment duration. Design/methodology/approach – The authors study unemployment histories of Italian workers using dependent competing risk models. The authors evaluate the impact of overeducation on wage using propensity score and treatment models. Findings – The authors show that overeducated have longer unemployment spells than their well-matched peers. This evidence implies that when assessing the impact of overeducation on wages, the duration of joblessness should be taken into account to evaluate possible additional unemployment scarring effects. The authors show that when controlling for unemployment spell duration the wage effect of overeducation significantly increases of about 7 percent. This result is supported by improvements in the sensitivity analysis. Originality/value – The findings are consistent with an interpretation of educational mismatch as a penalizing phenomenon in the individuals’ working life associated with long-term unemployment.
Less debt, more schooling? Evidence from cross-country micro data

teaching and research institutions in France or abroad, or from public or private research centers.L'archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques de niveau recherche, publiés ou non, émanant des établissements d'enseignement et de recherche français ou étrangers, des laboratoires publics ou privés.
Observatoire Pelagis boat surveys 2003-2021

Original provider: Observatoire PELAGIS UAR 3462 University La Rochelle - CNRS Dataset credits: Observatoire PELAGIS UAR 3462, University La Rochelle - CNRS Abstract: Since 2003, the Observatoire PELAGIS (La Rochelle University) participated to annual halieutic surveys, led by the IFREMER, to collect data on the distribution of marine top predators in order to estimate their relative abundance and preferred habitats in the Bay of Biscay, the Channel and the North Sea. Each year, three observers take place on board the vessel “Thalassa” to record sightings of seabirds, marine mammals, large fish and fishing boats, from dawn to dusk. Following distance sampling methods, visual censuses are made by two observers (while the third observer is resting) from the upper platform of the boat (min. 14m above the sea level). They are placed on each side of the deck, looking ahead for marine predator with an angle of 180°. For each sighting, the species and the number of individuals are recorded, as well as the behaviour, distance and angle (upon request). Purpose: One of the main advantages of this survey lays in its ecosystemic approach, which provides information on all the components of the food web (from planktonic organisms to predators) as well as data on the environmental parameters (sea surface temperature, salinity…). Interactions between prey and predators are complex in marine ecosystems, which are submitted to strong spatio-temporal variations. Thanks to ecosystem-based surveys, observed distributions and densities of marine predators can be related to the occurrence of their prey, providing to scientists and managers a better understanding of the marine ecosystems structure. Supplemental information: [2022-10-20] The records on 2016-09-21 got the longitude sign swapped. they are corrected. [2022-01-18] Data in 2020 and 2021 were appended. [2018-04-26] Data in 2016 and 2017 were appended. Time and group size of the sightings are not available online. They may be released upon request.
Working capital grant for SCORPION Stasik TADEUSZ,Stasik MARIA,Stasik ŁUKASZ,Stasik TOMASZ,Stasik MICHAŁ

The project concerns support to the entrepreneur in providing liquidity and support to day-to-day activities due to the financial difficulties that have occurred to the entrepreneur as a result of the COVID-19 outbreak. Financial assistance under scheme SA.57015 (2020/N)
Antibody engineering by natural selection and by design

Antibodies represent a powerful defense mechanism due to their capacity to link specific antigen recognition with effector functions and are currently developed as drugs for prophylaxis and therapy of infectious diseases. The generation of antibody diversity represents a remarkable example of protein engineering that is coupled to a stringent mechanism of clonal selection. In the ENGRAB project we propose first to develop an integrated bioinformatics platform to unravel the clonal dynamics of antibody responses and use it to formulate and test hypotheses on the factors that drive antibody selection in primary and recall responses, thus providing a rational basis for vaccination strategies. Second, we will establish the general relevance and impact of receptor-based antibodies, a new type of naturally engineered antibodies generated by templated DNA insertions into immunoglobulin genes. Third, we will use different bispecific antibody formats, including those produced by templated insertions, to engineer, in the same molecule, two binding sites for the HIV spike in order to increase neutralization potency and breadth. Fourth, we will engineer the Fc portion of antibodies to HSV, S. aureus and M. tuberculosis to increase their effector function through loss-of-binding to pathogen Fc receptors or gain-of-binding to human activatory Fc receptors. The program is strongly supported by preliminary findings and will deliver an innovative platform to interrogate natural antibody repertoires and new strategies to engineer antibodies to improve their therapeutic efficacy.   The ENGRAB project deals with mechanisms of antibody diversification and engineering with implications for vaccination and immunotherapy. It is therefore submitted to LS6. Given its translational potential it also falls within the scope of LS7.
HOME AGENT PROXIED MIPv6 ROUTE OPTIMIZATION MODE

A method apparatus, processor, and computer program product for wireless communication, including employing a communication interface to obtain a binding update message from a mobile node (MN). A data process is employed to analyze the binding update message for a network address of a corresponding node (CN). A communication interface is employed to initiate a long-life secure association between the CN and a network agent serving the MN if the binding update message contains the network address of the CN, wherein the long-life secure association enables the MN and CN to participate in a route optimized (RO) mobile communication session. The method may include employing a data processor to generate a binding cache entry for the network entity or a network component serving the network entity, wherein the binding cache entry includes a security key that facilitates a route optimized communication session with the network entity or the network component.
COOLING PLATE ASSEMBLY FOR A BATTERY TRAY AND METHOD OF MANUFACTURING SAME

A cooling plate assembly for cooling at least one battery module in a battery tray includes a first plate and a second plate disposed in stacked relationship with one another to collectively define a cooling channel extending therebetween. An adhesive is disposed between the first and second plate and extends along at least a portion of the cooling channel for structurally bonding the first and second plates to one another. At least one mechanical fixation is disposed adjacent the adhesive and extends between the first and second plates for maintaining a position of the first and second plates during a curing of the adhesive. A method of manufacturing the cooling plate assembly is also disclosed.
Simulation of Diesel Engine Intake Premixed Methanol with Different Injection Modes

Using the Eulerian gas equation and Lagrangian drop equation,a simulation model of intake injecting methanol for a diesel engine with helical port-valve-cylinder was proposed.The model consists of liquid droplet break-up,evaporation,collision and coalescence,as well as wall interaction of liquid droplets and wall film separation and valve seat liquid expelling.Methanol and air mixing process for methanol injected into the engine intake port was simulated to guide the methanol/diesel dual fuel engine modification.Bench test of the dual fuel engine shows that the cylinder pressure of model calculation is good agreement with that of experiment.Methanol injection timing directly affects the cyclic amount of methanol into cylinder.Methanol injection during inlet valve closed will be more readily atomized and mixed in the induction stroke.Methanol injection orientation is determined by the principle of decreasing methanol film on cold wall.Methanol concentration in cylinder is stratified more obviously in cylinder axis direction than that in cylinder radial direction.