SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Integration of nonlabyrinthine inputs by the vestibular system: Role in compensation following bilateral damage to the inner ear

Inputs from the skin and muscles of the limbs and trunk as well as the viscera are relayed to the medial, inferior, and lateral vestibular nuclei. Vestibular nucleus neurons very quickly regain spontaneous activity following a bilateral vestibular neurectomy, presumably due to the presence of such nonlabyrinthine inputs. The firing of a small fraction of vestibular nucleus neurons in animals lacking labyrinthine inputs can be modulated by whole-body tilts; these responses are eliminated by a spinal transection, showing that they are predominantly elicited by inputs from the trunk and limbs. The ability to adjust blood distribution in the body and maintain stable blood pressure during movement is diminished following a bilateral vestibular neurectomy, but compensation occurs within a week. However, bilateral lesions of the caudal portions of the vestibular nuclei produce severe and long-lasting cardiovascular disturbances during postural alterations, suggesting that the presence of nonlabyrinthine signals to the vestibular nuclei is essential for compensation of posturally-related autonomic responses to occur. Despite these observations, the functional significance of nonlabyrinthine inputs to the central vestibular system remains unclear, either in modulating the processing of vestibular inputs or compensating for their loss.
La Prevención del Fracaso Escolar en Educación Secundaria desde el Programa de Mejora del Rendimiento y del Aprendizaje

Con la finalidad de prevenir el fracaso escolar y facilitar la graduación en Educación Secundaria Obligatoria del alumnado con dificultades no atribuibles a su falta de estudio y esfuerzo, la Ley Orgánica de Mejora de la Calidad Educativa aprobó el Programa de Mejora del Aprendizaje y Rendimiento (PMAR). Siete años después de su puesta en marcha, este trabajo tiene como objetivos describir cómo se ha implementado y qué resultados ha obtenido PMAR en centros de Andalucía y Madrid. Primero, se realiza un estudio dedicado al análisis de la normativa que regula el programa en ambas comunidades autónomas. Segundo, se llevan a cabo entrevistas semiestructuradas orientadas a conocer la opinión de nueve responsables educativos de los departamentos de orientación. Los resultados evidencian limitaciones estructurales que afectan al desarrollo del programa en ambas comunidades y regulaciones normativas que explican un trato diferenciado del alumnado en cada territorio. Se pone de manifiesto la baja eficacia de esta medida como estrategia para prevenir el fracaso escolar y se concluye enfatizando la necesidad de repensar en apoyos más tempranos, sostenidos en el tiempo y que faciliten la inclusión del alumnado con dificultades en su grupo de pertenencia.
Pan-Arctic observing system of systems: implementing observations for societal needs

Arctic PASSION will address the urgent need for coordinated and accessible Earth observation and information services for the Arctic region. Despite significant international effort in the past, elements of the current pan-Arctic observing network still remain fragmented, disconnected, or have other critical shortcomings. Our aim is to overcome these shortcomings and to advance towards a fully integrated pan-Arctic Observing System of Systems (pan-AOSS). Working under the SAON framework and in partnership with rights-and stakeholders, Arctic PASSION will strengthen international scientific observations, community-based monitoring, and Indigenous knowledge and local knowledge within an observing system. We will co-create an innovative pan-AOSS that truly represents the diverse range of needs of the different user-groups and decision makers. 
The resultant pan-AOSS will provide its users with unrestricted access to the latest-available Arctic observations, including better access to Copernicus Arctic products. It will empower Arctic communities, policy makers and industries to make knowledge-based decisions. These will benefit society and support the adaptation and sustainability of the objectives of the UNFCCC, the IPCC and associated protocols. 
Arctic PASSION will also fill critical gaps in observations and improve the archiving, handling and interoperability of Arctic data systems. It will use these improvements to develop and implement eight new EuroGEO Pilot Services that will support emergency preparedness, food security, and responses to climate and socio-economic changes in the Arctic.
The combination of the work performed by Arctic PASSION will provide compelling evidence to GEO to update Arctic GEOSS’ Community activity’ to the higher level of GEO ‘Regional Initiative’.  Our legacy will be a stronger European voice in Arctic observing, and a more inclusive pan-Arctic observing system that supports a prosperous, sustainable and environmentally secure Arctic.
The FDA initiatives for personalized medicine

The FDA continues to be the Leader on the scientific front to build the regulatory infrastructure necessary to support the development of personalized targeted therapies. To this end the FDA has drafted guidance documents for industry to follow for both diagnostic and therapeutic research trials. For example, there has been an increase in companion diagnostics, the tests being used to determine whether or not a particular therapy may work for a patient. To address these issues, the FDA has published a draft guidance: In Vitro Companion Diagnostic Devices in July 2011, to communicate to Industry how the FDA defines these devices and what the regulatory requirements are for them. These guidelines should help to facilitate the process but will also help determine that the right patient received the right treatment for them. In addition, the FDA is reaching out to drug developers, academic investigators, patient groups, statistical and methodological experts and ethicists through a series of meetings to achieve a mutual understanding of the necessary steps to be taken when an investigational drug being studied for a serious disease with no alternative treatment option shows “exceptional” promise. Through the coordination of both arms of the FDA’s regulatory centers, CDRH (diagnostic approvals) and CBER and CDER (drugs, biologics and cell-based therapies), a more expedited pathway for approval will be possible. Draft guidances on any of these issues from the outcome of the above meetings as well as the FDA’s strategic plans to enhance their statistical and computational models will be issued by CDER. The most recent developments on any of the above will be addressed.
Edgetic perturbations to eliminate fixed-point attractors in Boolean regulatory networks

The dynamics of complex biological networks may be modeled in a Boolean framework, where the state of each system component is either abundant (ON) or scarce/absent (OFF), and each component's dynamic trajectory is determined by a logical update rule involving the state(s) of its regulator(s). It is possible to encode the update rules in the topology of the so-called expanded graph, analysis of which reveals the long-term behavior, or attractors, of the network. Here, we develop an algorithm to perturb the expanded graph (or, equivalently, the logical update rules) to eliminate stable motifs: subgraphs that cause a subset of components to stabilize to one state. Depending on the topology of the expanded graph, these perturbations lead to the modification or loss of the corresponding attractor. While most perturbations of biological regulatory networks in the literature involve the knockout (fixing to OFF) or constitutive activation (fixing to ON) of one or more nodes, we here consider edgetic perturbations, where a node's update rule is modified such that one or more of its regulators is viewed as ON or OFF regardless of its actual state. We apply the methodology to two biological networks. In a network representing T-LGL leukemia, we identify edgetic perturbations that eliminate the cancerous attractor, leaving only the healthy attractor representing cell death. In a network representing drought-induced closure of plant stomata, we identify edgetic perturbations that modify the single attractor such that stomata, instead of being fixed in the closed state, oscillates between the open and closed states.
Windscreen wiper connector assembly for a vehicle

The invention relates to a wiper connector assembly (10) for a vehicle (1), comprising a wiper blade connector part (12) and a wiper arm connector part (14), wherein one of the wiper arm connector part and the wiper blade connector part is a male connector (22) and the other one a female connector (24) for connecting the wiper blade connector part to the wiper arm connector part, wherein the male connector (22) has a biased protrusion (15) extending from an exterior (23) of the male connector in a radial direction (R) of the male connector and having a visual indicator portion (16), said male connector further comprising a user-operable arm (18) configured to cooperate with the biased protrusion and having a tab portion (19) reachable by a user from an outside of the male connector; the female connector (24) defines an interior surface (25) and comprises a groove (40) disposed on the interior surface, said groove defining a path (41) for the biased protrusion of the male connector and having a groove end (45) comprising a through hole for said biased protrusion; the groove path having at least a first path section (42) extending substantially in an axial direction (A) and a subsequent second path section (43) extending from the first path section and substantially in a circumferential direction (C) along said interior surface of said female connector.
Lucini ésotérique et vers-libriste : une interprétation cabaliste et prospective des Armonie sinfoniche

Les harmonies symphoniques sont un projet composite, apparemment rédigé par Lucini entre 1885 et 1888, dont seulement deux poèmes ont été publiés en 1892, ceux-là mêmes qui témoignent du premier emploi vers-libriste chez Lucini. Si ces deux poèmes marquent le début d’une expérimentation qui sera propre de la poésie symboliste et ‘futuriste’ de Lucini, plus tard considéré à bon escient comme l’inventeur du vers libre en Italie grâce à sa redécouverte par les néo-avant-gardistes italiens des années 1960, d’autres parties de ce projet de jeunesse restées inédites de son vivant montrent ses intérêts en matière de cabalisme. Sans sous-estimer les apports des années 1970 sur ce sujet, nous proposerons des sources possibles et une interprétation ésotérique plus approfondie de ces écrits, qui seront aussi envisagés par rapport à la production concomitante et future de Lucini.
Porcine enzootic pneumonia: relationship between microscopic lung and kidney lesions in Santa Catarina, Brazil = Pneumonia enzoótica suína: relação entre lesões microscópicas pulmonares e renais em Santa Catarina, Brasil

In this work the relationship between lung lesions of pigs with Enzootic Pneumonia and kidney lesions during sanitary inspection at slaughter was investigated. For this purpose sixty-nine Enzootic Pneumonia positive lung samples and sixty-nine negative ones as well as kidneys from the same pigs were post mortem examined. Microscopic examination revealed that 54.28% of the pigs (58/138) had both lesions, an association significant by Chi-square (P<0.05). The intensity of this association, by “Odds ratio” value of 0.2267 was also significant (0.09045-0.5683). Such result indicates that Porcine Enzootic Pneumonia positive pigs are more likely to develop nephritis. Although the relationship between lesions is uncertain, immunodepression caused by Porcine Enzootic Pneumonia is a probable cause of the concomitant renal disease.
USO DELLA CANZONE NELLA CLASSE DI LINGUA E CULTURA PER SVILUPPARE LA COMPETENZA SOCIOCULTURALE

Il presente articolo ha come obiettivo descrivere l’importanza dell’uso della musica nei corsi di lingua e cultura italiana per sviluppare non solo la competenza linguistica-comunicativa ma anche per sviluppare la competenza socioculturale e incentivare negli studenti, attraverso l’ascolto della canzone e l’analisi del testo, la riflessione critica in relazione alla propria esperienza e a quello che accade nella sfera sociale. In questo senso, il lavoro segue la metodologia della ricerca azione e in questo senso, si sono didattizzate quattro canzoni che sono state applicate nei corsi di lingua e cultura italiana presso un Istituto Italiano di Cultura e un’Università peruviana. I risultati ottenuti sono molto positivi perché permettono di evidenziare che la canzone può essere uno strumento autentico ricco di elementi linguistici, ma soprattutto è molto motivante e che è apprezzato positivamente dagli studenti. Con l’applicazione delle Unità di Apprendimento si conclude che la canzone è utile per affrontare aspetti sociali e riflettere sulla propria realtà e sulla propria esperienza di vita facendo parlare gli studenti su quello che pensano e vivono.&#x0D; &#x0D; Use of song in the language and culture classrooms to develop socio-cultural competence&#x0D; This article describes the importance of the use of music in Italian language and culture classes in order to develop not only linguistic-communicative competence but also socio-cultural competence. Through listening to songs and analyzing the texts, critical reflection in relation to the students’ own experiences and what happens in the social sphere was stimulated. Following action research methodology, four songs were taught in Italian language and culture courses at an Italian Cultural Institute and a Peruvian University. The results obtained were very positive because they highlighted how songs can be authentic tools rich in linguistic elements, but above all it was very motivating and appreciated by the students. In implementing the Learning Units, we concluded that songs were useful for addressing social aspects and reflecting on one's own reality and life experience by having students talk about their thoughts and experiences.
Physical Activity in Children: Prevention of Obesity and Type 2 Diabetes

There is strong evidence that increased physical activity is beneficial for blood glucose homeostasis and the prevention of obesity and type 2 diabetes mellitus. This chapter takes a life course approach with an emphasis on the intrauterine and childhood stages of life. Firstly, growth and development at critical periods with a focus on skeletal muscle and adipose tissue; then, obesity and type 2 diabetes mellitus are considered in relation to physical activity and sedentary behaviour. The importance of the development of fundamental movement skills in early childhood for both physical fitness and also growth and development is emphasised. Physical activity guidelines in westernised countries are examined for commonalities. Finally, the effective translation of the evidence base for the benefits of physical activity into randomised controlled trials and then into real-world public health services that are sustainable is addressed with a case study from New Zealand of Project Energize--a through-school physical activity and nutrition intervention. Physical activity, alongside a 'healthy diet' is arguably the best preventive measure and treatment for both obesity and type 2 diabetes. It is an essential and normal activity of daily life, and all aspects of the life course and the environment should support physical activity.
Disruptive process for the construction of railway transition zones, reducing drastically construction and maintenance costs

When a train crosses from an embankment area (soil) to a bridge, tunnel, viaduct or box culvert, there is an abrupt change in support conditions (strength and hardness, also known as vertical stiffness). Trying to to deal with these changes, that accelerate track degradations and generate vibrations, the embankment at the approaches to these concrete structures (transition zones) are designed and constructed differently compared to the rest of the track, using cement-treated soil to constitute a wedge shaped backfill. The construction process of current solution is complex, uncertain and time-consuming for construction companies.

Besides, the change of vertical stiffness is still not solved with present construction processes. This makes that maintenance needs of transition zones are up to 6 times higher than regular tracks being an additional cost for railway infrastructure managers (mainly public companies). It is estimated that annually 471M€ (10% European investment in track maintenance) is allocated to maintenance operations in transition zones, while these only account for 2,8% of the network length.

TORRESCAMARA has developed DIGITALIA, an innovative solution for transition zones based on precast concrete slabs that properly smooth vertical stiffness and maintain this performance over time, with the aim of: 1) Simplifying, speeding up and reducing costs of the construction process, as DIGITALIA is 60% cheaper than current solutions while taking just 10% of time 2) Reducing maintenance operations needed (equaling regular track needs) and costs, while increasing track availability for train operating companies, 3) Reducing the associated vibrations to improve passenger comfort.

Looking at Europe only, DIGITALIA opens the way to a market worth nearly 140 M€ by the 5th year.

In Phase 1, we will focus on the elaboration of a comprehensive business plan that ensures a quick market deployment through the development of a demonstration element in Phase 2.
Characteristics of interfacial signatures on a wind-driven gravity-capillary wave

[1] Direct numerical simulation of a wind-driven gravity-capillary wave and the underlying turbulent flow is conducted to identify the characteristic signatures of various surface parameters, including temperature, gas flux, velocities, and roughness, and to reveal the impacts of the nonbreaking surface waves on these surface flow and tracer parameters. Three characteristic surface signatures and the corresponding flow processes are identified: the carrier gravity wave, the parasitic capillary wavelets, and the elongated streaks. The elongated streaks are induced by both the coherent streamwise vortices formed within the turbulent shear layer and the Langmuir circulations arising from nonlinear interaction between the carrier gravity wave and the drift current. All three surface signatures can be observed in the distributions of various quantities, although some are more apparent than the others. Image-processing techniques, employing empirical mode decomposition and phase averaging, are developed to decompose the distinct signatures thus to quantify the contributions by the responsible flow processes. It is found that elongated streaks prevail the distribution of surface temperature and gas flux, indicating that Langmuir cells and the coherent eddies contribute to the major interfacial heat and gas transport. These eddies also induced strong cross-stream velocity divergence at the water surface, which exhibits resemblant elongated distribution as that of gas flux (correlation coefficient � 0.6). High correlation between the surface distributions of temperature and gas flux is observed (correlation coefficient � 0.8 to 0.9), suggesting that the spatial and temporal distribution of surface temperature is a good proxy tracer of interfacial gas transfer.
Paracoustics : system active sound reducing system against noise pollution due to transport

80 years of combined experience and 21 years of specific research allowed the team of DIDSON Company to develop and patent the Paracoustics® System: an active reducing sound system against noise pollution due to transport. This disruptive innovation is a revolutionary transducer for reflecting external noise waves. When this system is activated, it reflects the noise. As a result, there is a reduction of 25 to 30 dB of noise level, even when the windows are open. Our product is aimed at protecting coastal city centers, airports, ring roads, railway lines and places where heavy traffic disturbs life. The Paracoustics® system is a simple solution that allows residents to ventilate their building naturally while respecting the environment, saving energy and being in perfect harmony with the EU thermal regulations. The centerpiece of our system, the patented active Paracoustics® electroacoustic transducer is designed to be integrated as part of the closure elements: shutters, curtains and ventilation. A European market survey will be carried out to know the needs of our future clients and to verify that the market is ready to integrate this new innovation. We solicit the help of the EU-H2020 program - Phase 1, because this support would be for us a true accelerator to achieve the marketing of our product in optimal conditions. This will allow us to reach very quickly the European market and therefore to generate the jobs that go hand in hand with the development of our business.
Development of innovative palletising and depalletisation technology in the company EKALTECH BIURO System Engineering GLIŃSKI KRZYSZTOF

The main object of the project will be to carry out industrial research and development work aimed at developing an innovative technological line for palletising elements, including furniture. The project will contribute to the implementation of product innovation on the market, including the development of an unprecedented technological line – an autonomous system of palletisation and depalletisation It will be a unique solution on the market, which will allow to significantly improve warehouse processes. In order to achieve this objective, research will be carried out, including industrial research and development work: Step 1 – Developing the device design Stage 2 – Developing partial prototypes and testing according to the scope, including algorithms and strength tests Stage 3 – Developing the whole prototype and testing under operational conditions. Step 4 – Verification, modifications and real-world tests. Within the framework of the project, it is necessary to bear the costs of research work covering, inter alia, the remuneration of the research staff, the operating costs associated with the production of the prototype and the MSI necessary for the design work. These are described in detail in the following part of the proposal. Implementation of the project is planned in the period 01.04.2020-30.09.2021. The project will allow for the introduction of process and product innovation on the market, which is important both for the branches described in the application and from the point of view of environmental protection. This will be a key factor in increasing the competitiveness of the company over the next few years.
Thermal study in Eu3+-doped boehmite nanofibers and luminescence properties of the corresponding Eu3+:Al2O3

Eu3+-doped
 boehmite nanofiber materials with different Eu3+ concentrations were synthesized without any surfactant, and followed by a series of characterizations. It was found that the boehmite nanofibers became coarser with the increase of Eu3+ concentration, which resulted in a gradual decrease of their specific surface areas. Moreover, the thermal stability of the boehmite nanofibers was studied by thermogravimetry–differential scanning calorimetry. All materials showed the phase transition from γ-Al2O3 to other forms. Yet the transition temperature was increased with the increase of Eu3+ concentration. The Eu3+-doped boehmite nanofibers with the maximum Eu3+ concentrations showed the best thermal stability. Photoluminescence spectra showed that the 2 mol% of doping concentration of Eu3+ ions in Eu3+:Al2O3 nanofiber was optimum.