SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Ozone stomatal flux and O3 concentration-based metrics for Astronium graveolens Jacq., a Brazilian native forest tree species

The current levels of surface ozone (O3) are high enough to negatively affect trees in large regions of São Paulo State, southeastern Brazil, where standards for the protection of vegetation against the adverse effects of O3 do not exist. We evaluated three O3 metrics - phytotoxic ozone dose (POD), accumulated ozone exposure over the threshold of 40 ppb h (AOT40), and the sum of all hourly average concentrations (SUM00) - for the Brazilian native tropical tree species Astronium graveolens Jacq. We used the DO3SE (Deposition of Ozone for Stomatal Exchange) model and calculated PODY for different thresholds (from 0 to 6 mmol O3 m(-2) PLA s(-1)), evaluating the model's performance through the relationship between measured and modelled conductance. The response parameters were: visible foliar injury, considered as incidence (% injured plants), severity (% injured leaves in relation to the number of leaves on injured plants), and leaf abscission. The model performance was suitable and significant (R(2) = 0.58; p < 0.001). POD0 was better correlated to incidence and leaf abscission, and SUM00 was better correlated to severity. The highest values of O3 concentration-based metrics (AOT40 and SUM00) did not coincide with those of POD0. Further investigation may improve the model and contribute to the proposition of a national standard for the protection of native species.
Savings loyalty system based on micro-contributions from retailers

PENSUMO overall objective is to enable a secure and robust platform for stimulating consumers to save for the long term by
an innovative reward system based on micro-contributions generated in every single purchase. Why self-management of
savings is becoming so important? Financial wellness is becoming a trendy concept especially when we think in our future.
While a majority of people agree that their governments will not be able to provide sufficient retirement funds, this realization
is not translated into action: according to global surveys, only 38% are saving for old age, only 50% have some kind of
financial plan in place, and nearly one in five do not know what will constitute their income in retirement. The European
Commission has published a White Paper on Adequate, Safe and Sustainable Pensions. PENSUMO is an innovative model
of commercial relationship between users and traders (retailers and branders) pursuing a two-fold purpose: (i) Customer
Savings for the future (long-term) from the micro-contributions the retailers made in the Savings Plan consumer every time
they buy in their associated shops. (ii) The biggest consequence of widespread use of this system among citizens, would be
the birth of a new pillar of the pension system, complementary to the Public systems, with the particularity that is free and
voluntary for beneficiary.
Umbrella

The umbrella has a central shaft (1), and a ribbed assembly (2) that is pivotably attached to the shaft to fasten an umbrella body (3) to the ribbed assembly. A handle (4) is attached to a lower section of the shaft. A covering unit (5) has a connecting strip (51) that is attached to the handle, and a covering element (52) that is fastened to the connecting strip, where the covering element and the strip are made of cloth, fiber, plastic or elastic material. The covering element encloses the body and the handle when the umbrella is respectively folded and opened.
Southpark  - social and universal technology helping to detect arrivals via sdk

predict.io has been set up as a company to address individual, as well as societal problems related to urban mobility and road congestion by building a smart, integrated, technology-based, easy to use system that renders  the traffic more efficient thereby decreasing negative effects on humans and the environment while at the same time fulfilling today's need for fast and individualised urban mobility. The technology is based upon an elaborated set of algorithms that can detect on mobile devices when a user arrives at a location in order to improve different kinds of traffic and mobility apps. 

The SOUTHPARK project is set up to fulfil two overall objectives: 

First, predicto.io will integrate the technology, with its automated start and stop detection in different mobility apps (including parking apps). This will be achieved when the SDK generates at least 1 million mobility data points a day for real-time applications as well as business analytics. These efforts will cover countries across the European Union. The goal is to enable more convenient, more reliable, safer, environmentally friendlier, and efficient mobility solutions.

Second, the SOUTHPARK project will bring the arrival detection close to perfection. This will be reached by the reduction of localisation costs and implementation time. predcit.io will build up significant machine learning capacities that constantly improve the existing algorithms in order to provide faster, better anticipating, more adaptive and less battery consuming STOP detection. Fulfilling this objective will reduce the adaptation costs and time to localise to new settings by estimated 75%.

The outcome of the project will be an ensemble of algorithms that had been tested on large scale in the operational environment. The arrival detection can be used in various mobility use cases and provide data that  helps city planners and public transport authorities to better plan the future of urban transportation.
Debating heritage authenticity:<i>kastom</i>and development at the Vanuatu Cultural Centre

In October 2003, 28 cultural expressions from around the world were proclaimed Masterpieces of the Oral and Intangible Heritage of Humanity, complementing the adoption of the Convention for the Safeguarding of the Intangible Cultural Heritage by UNESCO. This proclamation has been part of the broader remit of the international organisation to protect the world’s cultural diversity from modernity and globalisation. Inherent in this is an underlying notion of cultural authenticity, implying that certain expressions, which are considered to be endangered and therefore in need of institutional protection, constitute ‘original’ and ‘pure’ manifestations of cultural identity. Taking forward debates on the safeguarding of intangible heritage, this paper examines cultural authenticity in the context of the Vanuatu Cultural Centre, the principal cultural organisation, museum and research institution of the Melanesian archipelago. The proclamation of the practice of sandroing (sand drawing) as a masterpiece of intan...
The EC-Earth3 Earth system model for the Coupled Model Intercomparison Project 6

The Earth system model EC-Earth3 for contributions to CMIP6 is documented here, with its flexible coupling framework, major model configurations, a methodology for ensuring the simulations are comparable across different high-performance computing (HPC) systems, and with the physical performance of base configurations over the historical period. The variety of possible configurations and sub-models reflects the broad interests in the EC-Earth community. EC-Earth3 key performance metrics demonstrate physical behavior and biases well within the frame known from recent CMIP models. With improved physical and dynamic features, new Earth system model (ESM) components, community tools, and largely improved physical performance compared to the CMIP5 version, EC-Earth3 represents a clear step forward for the only European community ESM. We demonstrate here that EC-Earth3 is suited for a range of tasks in CMIP6 and beyond.
Aluminum (Al) [Z = 13]

Despite its abundance, it was considered a rare and expensive metal until 1886, when Charles M. Hall of the United States and Paul L. T. Héroult of France independently discovered an inexpensive system for obtaining pure aluminum by electrolysis of its oxide (Al2O3).
International Center for veterinary education and information in animal health and food safety in pertnership with cross-border Balkan states

The project’s general objectives are to contribute to the overcoming of some problems that make it difficult for the crossborder process of
cooperation: different administrative, sanitary, educational and legislative systems. The specific objective are: To uniform, to harmonize and
to strengthen through continuous education and information, national and international veterinary systems, in relation to the application of
International O.I.E. standards, and also to the requirements of the European Union; To improve the quality of animal products; To strengthen and orientate the research and enhance its results dissemination, particularly in veterinary public health, food and animal product quality, and sanitary standards management in food producing enterprises;
Following protein diffusion in photosynthetic membranes with super resolution

The regulated diffusion of light-harvesting complexes in photosynthetic membranes is essential for photosynthesis, for instance for the redistribution of light-harvesting complexes between Photosystems I and II. To date, however, little is understood about the mobility of these proteins through the highly crowded membrane environment. In contrast to the huge amount of structural research that has been performed on biomolecules in the past, research on the dynamics is lagging far behind. The major limitation is the fact that the nanometer size regime of biomolecules is not accessible by classical optical techniques owing to the diffraction limit of light. To overcome this problem, we propose to use plasmonic nanoantennas, which are able to confine light at the nanoscale. In combination with Fluorescence Correlation Spectroscopy (FCS) this will allow measuring protein mobility in photosynthetic membranes with high, tens of nanometers, resolution. Directional and functional protein movement will be induced by illumination of the chloroplasts using specific light conditions; simultaneously following the protein movement will give new insights in how plants optimize their light harvesting capacity under fluctuating light conditions. The new nanoantenna-FCS based method, which we will develop to measure the diffusion of membrane proteins with nanometer resolution, has the potential to become widely used for nanobioimaging and ultrasensitive biosensing.
This research will be performed by Dr. E Wientjes in the Laboratory of Biophysics of Wageningen University led by photosynthesis expert Prof. H van Amerongen. A long-term collaboration will be started with Wientjes current supervisor Prof. NF van Hulst and Prof. MF Garcia-Parajo from the Institute of Photonic Sciences in Barcelona who are leading scientists in nanophotonics. The outcome of this project will provide biophysicists with a new method to study membrane protein dynamics with super resolution.
Radio PBX for personal communications system

A Radio PBX for use in a Digital Mobile Telephone system includes a plurality of transceivers to transmit and receive RF signals to and from subscriber units and/or an external base station in which at least one set of transmitter and receiver is communicating those RF signals, converting their frequencies and/or protocol, and said radio PBX is connected to one common antenna communicating with the subscriber unit and/or one common antenna communicating with the base station. The transceivers have a capability to convert said RF signals into base band signals and modulate them into new RF signals by adapting said base band signals between said transmitter and receiver. Moreover, each transceiver is tailored and/or automatically assigned for one of the Control trunk, Communication trunk, Local Line trunk, Service trunk, and/or Incoming and Outgoing Line trunk within a radio PBX. The control trunk is provided to synchronize with an external base station, and to control the control channel to and from an external base station and/or subscriber unit within a serving area. The communication trunk is provided to connect the communications between said base station and said subscriber units, and/or between the control trunk and said subscriber units. The local line trunk is provided to connect the communications between said subscriber units. The service trunk provides 3-way call bridge, voice mail, etc. The incoming and outgoing line trunk is provided to connect the communications between telephone lines and said subscriber units, and/or between telephone lines and communication trunks. The incoming and outgoing line trunk can be located remotely and can be connected to said radio PBX and/or communication trunks through open air propagation and/or existing CATV cable network and/or coaxial cable network. By the present invention, very cheap and higher traffic capacity of a radio PBX can be realized. And moreover, the higher efficiency in the channel usage can be ensured.
Influence of brain-stomach interactions on hunger, satiety and brain function

Hunger, satiety and feeding are complex phenomena exerting a profound influence on health and wellbeing. Hunger, or the mental urge to eat, is often associated with the feeling of an empty stomach. Satiety refers to a cascade of physiological, neural and metabolic mechanisms that inhibit further eating. Importantly, the decision making process in the brain that determines what, when and how much we eat is modulated by subconscious signals from the gut that can activate the brain’s dopaminergic system and reinforce dietary habits, explaining why so many people struggle to make healthy food choices and why the prevalence of obesity in developed countries is so high. Scientific knowledge on the brain-gut mechanisms behind hunger and satiety is incomplete, limiting our ability to develop efficient therapies and public policies targeting obesity and overweight. In BRAINSTOM, I have designed an innovative research program to study how the brain’s signatures of hunger and satiety are linked to the movements and contractions of the stomach, combining  my previous expertise in the simultaneous recording of the stomach and functional magnetic resonance imaging in humans with research methods from nutrition and metabolism and recent advances in positron emission tomography of the dopaminergic system. The three key hypotheses of my research proposal are that i) hunger feelings are associated with measurable changes in movements and contractions of the stomach ii) as food transits through the stomach, the brain releases dopamine and satiety feelings arise iii) the electrical activity of the stomach interacts with cortical, subcortical and neuromodulatory brain structures, influencing brain activity, interoception and cognitive functions beyond feeding. These findings will inform novel theories of brain-body interactions and will lead to the development of novel psychological and pharmacological interventions to reduce obesity and overweight.
Surveillance mechanisms regulating nuclear envelope architecture and homeostasis

The nuclear envelope (NE) is a major hub of eukaryotic cellular organization, influencing a myriad of processes, from gene regulation and repair to cell motility and fate. This central role of the NE depends on its elaborate structure, particularly on the organization of its inner nuclear membrane (INM). This peculiar membrane is continuous with the rest of the endoplasmic reticulum (ER) but faces the nucleoplasm and contains a distinctive set of proteins, which confer a unique identity to the INM. Importantly, mutations in several INM proteins result in a wide range of diseases, such as muscular dystrophies and premature aging syndromes, highlighting the key roles of the INM proteome in cell homeostasis. However, the mechanisms establishing and maintaining the INM proteome identity and integrity have remained mysterious.
 
My lab recently identified a quality control system that, by targeting aberrant proteins for degradation, regulates INM identity and homeostasis. This proposal describes a framework to expand our findings and to provide a comprehensive and integrated understanding of the INM proteome. By combining my expertise in membrane protein analysis with newly developed proximity biotinylation and proteomics approaches, we will for the first time probe the complex INM environment of living mammalian cells. A systematic examination of the INM proteome, its turnover rates and changes in response to different physiological conditions will reveal functions of INM proteins and their regulatory pathways. Moreover, it will characterize INM surveillance mechanisms and evaluate their contributions to NE proteostasis.
 
In sum, this proposal will provide a panoramic yet detailed view of the mechanisms underlying INM functions, identity and homeostasis, both in interphase and during NE reformation in mitosis. Given the clinical relevance of many INM proteins, our studies may illuminate current understanding of diseases such as laminopathies and cancer.
HYBRID NANOPORE DEVICE WITH OPTICAL DETECTION AND METHODS OF USING SAME

Devices or systems comprising a protein nanopore immobilized in a lipid layer within an aperture of a solid phase substrate, which provides a stable platform for using first and second members of one or more FRET pairs to generate optical signals as a labeled analyte, such as a polynucleotide, translocates through the bore of the protein nanopore, are provided. In certain variations, the device or system may be used to determine the nucleotide sequence of a polynucleotide analyte.
Nano traction

In this Marie Skłodowska-Curie Fellowship project entitled “Nano Traction” I will design a platform for the directed autonomous movement of nano- and microparticles. This will be achieved using a completely novel form of traction based on the dynamic covalent attachment of the particles to a surface.  Asymmetrically applied redox potentials will induce motion allowing the electrical control of nano- and microparticle motion and the creation of particles that autonomously move and seek out cells that are producing reactive oxygen species a key indicator of disease.  This Fellowship will be undertaken under the supervision of Prof. Molly Stevens in the Division of Biomaterials and Regenerative Medicine at the Karolinska Institute (KI), which has the world-leading expertise in functional nanomaterial synthesis, biomaterials engineering, cell biology and tissue engineering crucial to the objectives of this proposal. This ground-breaking new method of particle control at micro and nanometre length scales will have application in many areas including; precision actuation for nanorobotics and microfluidics and; the creation of cell seeking particles for biosensing and the targeted delivery of nanoparticle agents. It will not only initiate new research areas at the cutting edge of nano- and biomaterials science, but will help me to establish my own independent research career following the proposed Fellowship.
International  centre of competences for Innovation in the Mediterranean countries

The project arises from the results of the previous INNOVA project financed by INTERREG IIIA Greece-Italy 2000-2006. On the basis of the feasibility study drawn up from the project on the creation of a school INNOVA - Transnational School of Innovation and from the protocol of intent on its creation, the present project aims to establish and operate a school/centre of transnational skills as a result of widening the established network to favour territorial aggregation and the development of innovation in strategic productive sectors: Energy & Environment, Culture & Tourism, Agro-alimentary, Information & Communication Technology
APPARATUS AND METHOD FOR COUPLING MICROFLUIDIC SYSTEMS WITH A MASS SPECTROMETER UTILIZING RAPID VOLTAGE SWITCHING

The invention relates to an apparatus for coupling microfluidic systems with electrospray ionization mass spectrometry utilizing a hydrodynamic flow. The invention also relates to a method of preventing a sample in a main channel (25) of a microfluidic device (11) from migrating down either a first side channel (31) or a second side channel (33) by rapidly alternating a voltage being applied to the first side channel (31) and the second side channel (33).
Parkinson disease with mild cognition impairment treated with nicotinic agonist drug

Parkinson Disease (PD) is the second most common neurodegenerative disease after Alzheimer’s disease. There is an unmet clinical need to treat Parkinson disease with mild cognitive impairment (PD-MCI). There is ample evidence from epidemiological studies as well as (pre)clinical research that Nicotinic receptors are involved in PD and cognition. Recently a clinical trial suggested that selective α7 nicotinic receptor agonist improved cognition in PD patients, as a secondary outcome measure. Hence, the main goal of PD-MIND is to show the potential of the Astrazeneca nicotinic α7 agonist AZD0328 in a randomized, placebo-controlled, international multicentre, cross-over study on cognition in people diagnosed with PD-MCI. We will assess the Attention Intensity Index composite score from the CogTrackTM system as primary outcome measure and other clinical aspects (cognition, motor symptoms) as secondary outcomes. In addition, blood, CSF and imaging biomarkers will be assessed as potential predictors of response, and as marker of target involvement. Patients (Public and Patient Involvement) and other stakeholders will be engaged from the start to allow integration of end-user perspectives in the design and execution of the project. PD-MIND will put considerably effort to disseminate and exploit clinical outcome data and biomarker results, and to sustain the partnership for subsequent phase 3 clinical studies. PD-MIND consortium consist of world-leading PD-MCI experts in the area of clinical trials, clinical coordination, project management, data management and analysis, and biomarkers. As such the consortium is well positioned to execute the proposed work and complement the EFPIA members.
Autoxidation, and its Inhibition, in Anhydrous Lanolin

Abstract Long-term storage tests under good and bad conditions, and accelerated active oxygen method tests, have shown that autoxidative degradation of anhydrous lanolin can be satisfactorily inhibited for at least 32 months under good conditions or 2 years under bad conditions by 100 p.p.m. of butylated hydroxytoluene or butylated hydroxyanisole. Good results from other antoxidants, and disadvantages of some, are reported. Different lanolins are affected to different degrees, possible reasons being suggested, but autoxidation when uninhibited does not penetrate deeper than 1 cm. even after 2 years of adverse conditions; there is a fall in melting point and formation of up to 4.7 per cent of water-soluble substances including low-molecular weight acids. Absence of change in iodine value and rapid increase of acidity in darkness are contrary to previous reports.