SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Digital solutions supporting continuum of care for frailty prevention in old adults

Longevity is one of the biggest achievements of modern societies. By 2020, a quarter of Europeans will be over 60 years of age. Combined with low birth rates, this will bring about significant changes to the structure of European society, which will impact on our economy, social security and health care systems.

The most problematic expression of population ageing is the clinical condition of frailty. Frailty develops because of age-related decline in multiple physiological systems. It is estimated that a quarter to a half of people over 85 years are frail , and this is set to reach epidemic proportions over the next few decades. While frailty increases, the average amount of health spending increases as well with the frailty level  in a range from 1,500 to 5,000 €/person year, depending upon the frailty status and the setting of care. Frailty usually comes along associated with another risk facto; loneliness. 

Then, ageing, frailty and loneliness constitute overlapping conditions submitted to multiple health and care interventions. 

eCARE project aims to deliver disruptive digital solutions for the prevention and comprehensive management of frailty to encourage independent living, wellbeing and to relieve health and care services budget pressure, throughout the implementation of a Pre-Commercial Procurement scheme. 

Solutions should improve outcomes for frailty in old adults entailing the physical and the psychosocial factors. The target group are the pre-frail/frail old adults with emphasis on those that feel lonely and/or isolated.

The project will procure the development, testing and implementation of digital tools/services and communication concepts to facilitate the transition to integrated care models across health and social services and country-specific cross-institutional set-ups, including decentralised procurement environments and collaboration across institutions.
Features of the first alcohol test – subsequent attitude of 6 th year students at the State Medical University in Grodno, Belarus

Objective. To clarify the mechanism of initiation of young people to alcohol, determine what factors influence this process, and identify the particular attitude to alcohol at a young age. Materials and method. 188 graduates of the medical university were interviewed in 2010. A questionnaire was developed in the Department of Social Medicine at the Karol Marcinkowski University of Medicine in Poznan, Poland: Kwestionariusz ankiety dotyczacej konsumpcji napojow alkoholowych i aktywnosci fizycznej’ (2006). Results. It was found that 97.6% of students consciously drink alcohol. The average age of first use of alcohol was 15,4±0,48. Most young people have consumed alcohol for the first time (more beer, champagne, wine) in a club (disco) and at home (at a family celebration). Most often, respondents (46.4%) have tried alcohol on their own initiative at a family celebration. About 7.14% of students regretted drinking alcohol for the first time (from shame, quarrels with parents, physiological discomfort). 92.86% did not have feelings of regret because, in most cases, the first sample of the alcohol did not cause any reaction from parents or other relatives. 84.52% had used alcohol in the last 30 days: beer – 36.9%, wine – for 33.3%, and vodka – 28.6%. One-third had used alcohol once or twice in the last month, 16.67%-twice a week, 13.1% – one day a week. On the question of the causes of alcohol use, half of students responded: ‘to relax’ or ‘family holidays’; every fifth – ‘for the company’, one in ten ‘in response to good toast’ or simply because ‘I like it’. The most common negative result of alcohol consumption (almost every fourth) was because of smoking. Lapses in memory after alcohol were noted in 20 (23%) of students, actions provoked by alcohol and subsequently regretted were stated by 17.86% of respondents. One third of the students regret that they ever drank. Although two-thirds thought about the effects of alcohol, only a quarter limit its use. Application area: the results obtained are the basis for the development and introduction of measures of prophylaxis, for the attachment of alcohol among young people, first of all – work with the family, as well as educational work in schools, colleges and universities. Degree of introduction: the results were presented at a scientific conference in Grodno and introduced into the educational process at the Department of Public Health and Health Care. As a result of the study, talks were conducted with the students on the theme ‘Bad Habits in Modern Society’.
Gestione delle risorse degli ecosistemi acquatici del litorale del Mediterraneo: gli Echinidi eduli

The main objective is to asses the herbivorous activities (Paracentrotus
lividus) over prairie of Posidonia oceanic and in places with high-low pressure for sea hurcin. The project aim to empty the „loading capacity“ of the posidonia prairie and human influence.
In order to asses the effect over the „ sea hurcin source“ and the consequences for the Posidonia Oceanic (which is eaten by the sea hurcin), it will be made detentions in an area where fishing is forbidden and in another one where it is allowed for all. The two zones will be distant in order to avoid general influences (sea conditions, flows, bottom conditions etc.).
The two areas are Marina Protetta in the Parco Nazionale of La Maddalena and a proximal area to it.
Healthcare at the borders: managing camps and informal settlements for refugees and migrants

The management of migrants, refugees and asylum-seekers is one the most complex issues the EU is facing: HeBo aims to tackle it from the perspective of healthcare implementation in migrant camps and informal settlements situated within the European territory. In such spaces, both healthcare actions and their omission assume specific meanings, including the form of border management technology. HeBo thus focuses in particular on the following main research objects: A) the management of migrants in contemporary Europe through the lens of the right to healthcare, B) the relationship between the implementation of the right to healthcare and European border policies, and C) the implementation of the right to health as a translation of the politics of life and the differentiated judgement of lives underlying the current migration management in the EU. While the implementation of healthcare in humanitarian contexts has been largely studied in extra-European countries, it remains understudied for camps and, in particular, informal settlements within the European space. Through ethnographic inquiry on governmental and non-governmental healthcare units, HeBo focuses on three crucial sites across the EU: the islands of Lampedusa (Italy) and Lesbos (Greece), and the area of Calais (France). HeBo will build on the expertise that Dr. Alunni developed in his previous work on healthcare within Roma camps in Italy. Professor Didier Fassin, who will supervise HeBo, is a leading scholar in the field of humanitarianism and on issues of power and health inequalities, and will therefore support Dr. Alunni with his experience. Due to the excellent quality of its infrastructure, scholarly research and staff, the IRIS (Interdisciplinary Research Institute in Social Sciences) at the EHESS (École des Hautes Études en Sciences Sociales, Paris) will constitute the most appropriate academic environment for Dr. Alunni to become a leading social science scholar in the European Research Area.
Thermal stability of brine foams for shale gas drilling

Abstract Producing gas from shale gas reservoirs is challenging because of the non-darcy permeability of the pay rock. Gas well productivity is reduced by formation damage due to the shaly nature of the producing zone. Brine foams have been used as drilling fluids in shale gas drilling to improve well performance. While the thermal stability of foam is a big concern in deep well drilling, this issue has not been investigated for brine foams. This paper presents the result of our investigations on thermal stability of foams made from two brines and compared with foam from fresh water. Thermal stabilities of three foam systems were investigated in laboratory conditions at a temperature of 170 °F. They are fresh-water-based foams, KCl-solution-based foams, and CaCl 2 -solution-based foams. AQF-2 and HC-2 were used as foaming agents. Guar-gum, Xanthan-gum, and HEC were used as foam viscosifiers. We found that the stability of brine foams are more significantly influenced by viscosifiers than fresh water foams. Guar-gum can generate foam from KCl-solution that is as stable as that from fresh-water. Xanthan-gum can generate foam from CaCl 2 -solution that is as stable as that from fresh-water. This paper provides engineers with basic data necessary for formulating the most stable foams for shale gas drilling.
UNDERWIRED BRA AND GARMENT, IN PARTICULAR LINGERIE ITEM HAVING SUCH A BRA

- Underwired bra and garment, in particular lingerie item having such a bra. - The bra (1) comprises at least two cups (4, 5) and two curved underwires (6, 7), each of the underwires (6, 7) being associated with one of the cups (4, 5), each of the underwires (6, 7) having a so-called joining end (6B, 7B) and a so-called free end (6A, 7A), the two cups being joined by means of their respective joining end (6B, 7B), the joining ends (6B, 7B) of the two cups (6, 7) intersecting at the join.
Classroom emotional climate, student engagement, and academic achievement.

The emotional connections students foster in their classrooms are likely to impact their success in school. Using a multimethod, multilevel approach, this study examined the link between classroom emotional climate and academic achievement, including the role of student engagement as a mediator. Data were collected from 63 fifth- and sixth-grade classrooms (N 1,399 students) and included classroom observations, student reports, and report card grades. As predicted, multilevel mediation analyses showed that the positive relationship between classroom emotional climate and grades was mediated by engagement, while controlling for teacher characteristics and observations of both the organizational and instructional climates of the classrooms. Effects were robust across grade level and student gender. The discussion highlights the role of classroom-based, emotion-related interactions to promote academic achievement.
(14508.17092020.172001546) BARLIDIA

DER KAFFEE? PRINZ? EINE SEHR EINLADENDE BAR IM HISTORISCHEN ZENTRUM VON FLORENZ. PRÄSENTIEREN SIE DIESES PROJEKT WARUM? DER BESITZER BEABSICHTIGT, INNERHALB DES RAUMES EINE NEUE BANK FÜR DIE ZUBEREITUNG VON SANDWICHES UND SALZIG FÜR DIE VERWALTUNG AN UNSERE KUNDEN UND AUCH FÜR DAS MITNEHMEN ZU SCHAFFEN. ALLES MIT SEINER NOTWENDIGEN AUSSTATTUNG UND EINEM NEUEN SCHAUFENSTER FÜR DIE AUSSTELLUNG DER WAREN. ART DER INVESTITION: INVESTITIONEN IN AUSRÜSTUNG FÜR AKTIVITÄTEN? UNTERNEHMEN.
Alma – the key to the sun’s coronal heating problem.

How are the outer layers of the Sun heated to temperatures in excess of a million kelvin?  A large number of heating mechanisms have been proposed to explain this so-called coronal heating problem, one of the fundamental questions in contemporary solar physics. It is clear that the required energy is transported from the solar interior through the chromosphere into the outer layers but it remains open by which physical mechanisms and how the provided energy is eventually dissipated. The key to solving the chromospheric/coronal heating problem lies in accurate observations at high spatial, temporal and spectral resolution, facilitating the identification of the mechanisms responsible for the transport and dissipation of energy. This has so far been impeded by the small number of accessible diagnostics and the challenges with their interpretation. The interferometric Atacama Large Millimeter/submillimeter Array (ALMA) now offers impressive capabilities. Due to the properties of the solar radiation at millimeter wavelengths, ALMA serves as a linear thermometer, mapping narrow layers at different heights. It can measure the thermal structure and dynamics of the solar chromosphere and thus sources and sinks of atmospheric heating. Radio recombination and molecular lines (e.g., CO) potentially provide complementary kinetic and thermal diagnostics, while the polarisation of the continuum intensity and the Zeeman effect can be exploited for valuable chromospheric magnetic field measurements. 
I will develop the necessary diagnostic tools and use them for solar observations with ALMA. The preparation, optimisation and interpretation of these observations will be supported by state-of-the-art numerical simulations. A key objective is the identification of the dominant physical processes and their contributions to the transport and dissipation of energy. The results will be a major step towards solving the coronal heating problem with general implications for stellar activity.
Making earth green again with liquid nano clay

We urgently need to fight desertification by restoring areas of the world historically bread baskets suffering from erosion, harvests lost and poor water quality. Farmers and government authorities desperately need a fast-acting sustainable land management solutions to protect over 1 billion livelihoods. 

Until now this has proven incredibly challenging as available technology and methods require years to get arid soils strong enough to retain water. 

Desert Control can convert arid lands into fertile soils in a matter of hours with a patented mixing process to create Liquid NanoClay (LNC). This clay and water compound is sprayed onto sandy soils, quickly penetrating them at depths of 60 cm and enabling them to retain water and nutrients and host plant boosting fungi creating conditions for fertile land. 

Our first demonstrations with farmers in the UAE, the Agricultural Research Centre in Egypt, Ministry of Interior in Abu Dubai and the Sinai Governorate have successfully shown that LNC treatment can reduce the need for irrigation by up to 77% and increase soil fertility up to 40% leading to 416% higher yields. 

After the success of our first demonstration, we got the attention of large-reaching organizations such as BBC and the World Wildlife Foundation WWF who has identified us as a world Climate Solver Transforming arid lands will help mitigate climate change by reducing land’s surface temperature to 15°C, with just 1% of the planet’s arid land treated with LNC, these spaces could absorb 26 million tonnes of CO2 a year! To make LNC available for the people who need it, the agricultural sector, desert return projects and commercial and private greenery and provide unquantifiable benefits to society and the natural environment we need €2.5M to redesign our existing prototype for a transportable, commercial mixer. These units will be  licensed all over the world to create endless amounts of LNC on-site.
NOVEL ANTIBIOTIC COMPOUNDS

Glycopeptide antibiotics MM 47761 and MM 49721 of formula (I), wherein R is chlorine or hydrogen are produced by Amycolatopsis orientalis strain NCIB 12608.
Retail channel price discrimination

This paper examines price differentials of identical items across retail channels. Many consumer packaged goods are sold through both grocery and drug stores. Liquor is unique in that in much of the country there is a third retail channel of distribution, liquor stores. If consumers in each retail channel differ in their willingness to pay for certain items, then sellers can exploit those differences and charge different prices for the same items in each channel. We examine a unique data set of pooled cross sectional retail scanner data on wine to test whether sellers use retail channel to identify heterogeneous consumer market segments and engage in price discrimination. We begin by presenting a model of price discrimination by retail channel along with behavioural assumptions regarding shoppers in each channel. Next we examine sales by retail channel and find persistent price differentials for the same item across retail channel after controlling for sample selection bias and seasonality. Lastly, we estimate the price elasticity of demand correcting for endogeneity and find differences across channel consistent with the price differentials. The extent of price differential, however, differs significantly with respect to price point.
Privacy-Preserving Patient-Centric Clinical Decision Support System on Naïve Bayesian Classification

Clinical decision support system, which uses advanced data mining techniques to help clinician make proper decisions, has received considerable attention recently. The advantages of clinical decision support system include not only improving diagnosis accuracy but also reducing diagnosis time. Specifically, with large amounts of clinical data generated everyday, naïve Bayesian classification can be utilized to excavate valuable information to improve a clinical decision support system. Although the clinical decision support system is quite promising, the flourish of the system still faces many challenges including information security and privacy concerns. In this paper, we propose a new privacy-preserving patient-centric clinical decision support system, which helps clinician complementary to diagnose the risk of patients' disease in a privacy-preserving way. In the proposed system, the past patients' historical data are stored in cloud and can be used to train the naïve Bayesian classifier without leaking any individual patient medical data, and then the trained classifier can be applied to compute the disease risk for new coming patients and also allow these patients to retrieve the top- k disease names according to their own preferences. Specifically, to protect the privacy of past patients' historical data, a new cryptographic tool called additive homomorphic proxy aggregation scheme is designed. Moreover, to leverage the leakage of naïve Bayesian classifier, we introduce a privacy-preserving top- k disease names retrieval protocol in our system. Detailed privacy analysis ensures that patient's information is private and will not be leaked out during the disease diagnosis phase. In addition, performance evaluation via extensive simulations also demonstrates that our system can efficiently calculate patient's disease risk with high accuracy in a privacy-preserving way.
Parkassistenzvorrichtung für ein Fahrzeug und Einparksteuerungsverfahren davon

Es werden eine Parkassistenzvorrichtung für ein Fahrzeug und ein Einparksteuerungsverfahren davon bereitgestellt, die in der Lage sind, eine Kollision mit einem Stopper innerhalb eines Parkplatzes verhindern zu können, indem sie das Einparken in einer Ausrichtung mit einer Einparkreferenzlinie unterstützen, die in Bezug auf ein Objekt festgesetzt worden ist, das sich in einem Abstand am nächsten zu dem eigenen Fahrzeug unter Abständen zu Objekten befindet, die sich um einen gefundenen Parkplatz herum befinden. Die Parkassistenzvorrichtung weist Folgendes auf: eine Parkplatz-Sucheinheit, die dafür konfiguriert ist, nach einem Parkplatz für das Parken eines eigenen Fahrzeugs zu suchen; eine Empfangseinheit, die dafür konfiguriert ist, Erfassungssignale zu empfangen, die ausgehend von Objekten erfasst werden, die sich um den Parkplatz herum befinden; eine Referenzobjekt-Ermittlungseinheit, die dafür konfiguriert ist, die Erfassungssignale zu verwenden, um ein Objekt, das sich am nächsten zu dem eigenen Fahrzeug befindet, unter den Objekten, die sich um den Parkplatz herum befinden, als ein Referenzobjekt zu ermitteln; und eine Einparkreferenzlinien-Festsetzungseinheit, die dafür konfiguriert ist, die Einparkreferenzlinie auf der Grundlage eines vorderen Endes des ermittelten Referenzobjekts festzusetzen.
CD99 and CD99L2 act at the same site as, but independently of, PECAM-1 during leukocyte diapedesis

Abstract Leukocyte extravasation depends on various adhesion receptors at endothelial cell contacts. Here we have analyzed how mouse CD99 and CD99L2 cooperate with PECAM-1. We found that antibodies against mouse CD99 and PECAM-1 trap neutrophils between endothelial cells in in vitro transmigration assays. A sequential function, as has been suggested for human PECAM-1 and CD99, could not be demonstrated. In contrast to these in vitro results, blocking CD99 or CD99L2 or gene disruption of PECAM-1 trapped neutrophils in vivo between endothelial cells and the underlying basement membrane as revealed by electron microscopy and by 3-dimensional confocal fluorescence microscopy in the inflamed cremaster tissue. Leukocyte extravasation was inhibited in interleukin-1β-inflamed peritoneum and in the cremaster by PECAM-1 gene disruption and was further attenuated by blocking antibodies against CD99 and CD99L2. In addition, CD99 and CD99L2 were required for leukocyte extravasation in the cremaster after stimulation with tumor necrosis factor-α, where the need for PECAM-1 is known to be bypassed. We conclude that CD99 and CD99L2 act independently of PECAM-1 in leukocyte extravasation and cooperate in an independent way to help neutrophils overcome the endothelial basement membrane.
VAPOR-PHASE CATALYTIC CONVERSION OF ETHANOL INTO 1,3-BUTADIENE ON Cr-Ba/MCM-41 CATALYSTS

Al-MCM-41, 16%Ba/Al-MCM-41 and 1.4%Cr-16%Ba/Al-MCM-41 were used as catalysts in the vapor-phase catalytic conversion of ethanol. Physical-chemical properties of the catalysts and the effect of barium and chromium on the Al-MCM-41 activity and 1,3-butadiene yield were studied. The catalysts were characterized by X-ray diffraction (XRD), N2 physisorption (BET method), CO2chemisorption and Fourier transform infrared spectroscopy (FT-IR). When ethanol was completely converted on Al-MCM-41 and 16%Ba/Al-MCM-41, the reaction products showed a high selectivity for ethylene (90-98%). However, on the 1.4%Cr-16%Ba/Al-MCM-41 catalyst, a greater number of reaction products were obtained such as ethylene, acetaldehyde, diethyl ether and 1,3-butadiene. The maximum 1,3-butadiene yield obtained from ethanol reaction was 25% at 723 K and W/FEtOH = 15 g h mol-1. The latter result was obtained in a single step and without addition of reaction promoters (e.g., acetaldehyde, crotonaldehyde, hydrogen) in the feed stream to the reactor.
FLUE GAS INJECTION FOR HEAVY OIL RECOVERY

A variety of methods for thermal recovery of natural gas and bitumen from a formation containing the latter. In general, the methods incorporate a series of existing, but previously uncombined technologies. A modified flue gas from the steam generators conventionally used in a SAGD recovery operation is injected into the formation to enhance recovery with the produced fluids, natural gas, bitumen, inter alia are further processed. The injection of the flue gas conveniently is disposed of and further acts to repressurize the formation which otherwise becomes depressurized when depleted of natural gas. Accordingly, environmental and economic advantages are realized with the methodology.
NEW MANDELIC ACID DERIVATIVES AND THEIR USE AS THROBIN INHIBITORS

There is provided a compound of formula (I) wherein R<a>, R<1>, R<2>, Y and R<3> have meanings given in the description and pharmaceutically-acceptable derivatives (including prodrugs) thereof, which compounds and derivatives are useful as, or are useful as prodrugs of, competitive inhibitors of trypsin-like proteases, such as thrombin, and thus, in particular, in the treatment of conditions where inhibition of thrombin is required (e.g. thrombosis) or as anticoagulants.