SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Predicting response to depression treatment

Depression is a leading cause of disability and produces a greater decrement in health than other common chronic diseases such as angina, arthritis, asthma and diabetes.  In Europe, it is estimated that 7.2% of the disease burden is caused by depression with associated costs of €118 billion.  It generally takes months before clinicians are able to identify an effective antidepressant treatment for individual patients and during this period a patients’ ability to work and function socially is severely impaired by their illness. We will address this problem using the Primary Care –Emotional Test Battery (PC-ETB) a medical device that is sensitive to changes in negative emotional bias, an early biomarker for the effectiveness of antidepressant treatment. Identifying early, rather than late in treatment, if an antidepressant is working will significantly reduce the time required for the patient to get better and return to normal life.  The PC-ETB has been developed from a more extensive product battery that we provide to the pharmaceutical industry for drug development. In Phase 1 we will: (i) Assess the feasibility of using the PC-ETB in primary care in Europe; (ii) Determine how to set up a multinational medical device clinical investigation in Europe; (iii) Expand a health economic assessment conducted in the UK to include other major European countries and demonstrate the healthcare and societal benefits across Europe; (iv) Develop a commercialisation strategy across the major European countries by conducting a market research assessment of the market size, route to adoption, pricing and reimbursement mechanisms. In Phase 2 of the project we will conduct clinical validation of multi-lingual versions of the PC-ETB in a number of European countries. This innovative project is designed to complete the clinical validation of the PC-ETB and enable its launch as an internet delivered product to improve the management and treatment of depression across the European market.
Industry 4.0 technologies and circular economy: The mediating role of supply chain integration

Abstract There is a great expectation that Industry 4.0 technologies will enable better circular economy (CE) results at firms. However, it is unclear how these technologies might contribute to CE. We hypothesize that Industry 4.0 technologies are positively related to the level of integration among actors along the supply chain and within the firm supply chain integration (SCI), which, in turn, explains superior CE results. By employing partial least square structural equation models on original survey data based on a sample of more than 1200 Italian manufacturing firms and almost 200 adopters, we find that disentangling for the type of technologies is essential to understanding both their direct and indirect role toward CE. Smart manufacturing technologies have a stronger impact on CE outcomes than data processing technologies; the mediating effect of SCI is verified for the former but not for the latter type, questioning the possibility for those technologies to support sustained CE performance in the long run.
Norrdigi revolutionary energy saver

Norrhydro Oy is a Finnish hydraulic cylinder manufacturer. Since 2007, Norrhydro has developed a technology, NorrDigiTM, that has the ability to regenerate, store and share energy by the functions on mobile equipment, such as excavators, the largest market for cylinders. The economic effect of NorrDigiTM is very significant. It requires less space, is cost neutral and has proven 45-60% fuel efficiency improvement and 5-12% productivity gains in side-by-side tests with a standard excavator. NorrDigiTM is a modular control system made of highly engineered hydraulic cylinders, control valves, sensors and electronics in an integrated control package and is patented in all major countries. The initial target market is crawler excavators and large material handling equipment. The current addressable market size is 4,0 billion euros yearly. The first goal is a 5,6% market share by 2025, which means total sales will grow from 19 to 260 million euros in that period. The next target is 15% market share by 2028, which coupled with growth in adjacent markets will amount to over 800 million in annual sales. The imminent market launch is based on finalizing the product designs, testing, production investments and increased marketing. The solution is scalable, and Norrhydro performs an internal investment and LEAN improvement program to meet the increased volume demands. The other main components are modular and come from suppliers who have ample capacity. The direct effect on employment goes from 126 people in 2017 to 700 people by 2025. The SMEI-funding will assist in speeding up the launch, reduce risks, and improve the economics and the environment due to the drastically reduced fuel consumption (emissions). The funds will help securing additional financing which is planned as an IPO in 2020. The team leading the effort consists of dedicated, motivated and highly experienced professionals with long international track records of successful product and technology launches.
The rationale and ramification of sentencing and punishment in china through a gender based perspective

The proposed research project plans to explore the rationale and ramification of sentencing and punishment in contemporary China through investigating cases concerning gender and sexual identity, that is, sexual violence, sexual assault of minors/girls, and domestic violence, as well as the abuse of the criminal law in incriminating acts promoting the rights of sexual minorities. This research will provide a much-needed while still under-studied evidence-base, examining the relationship between gender and sexual identity and the criminal justice system in China, analysing to what extent the criminal law is utilised and/or abused in causing human rights violations. Based on the examination, the project will study civil society activism advocating for gender equality and the rights of sexual minorities in China as a critical bottom-up approach to address rights violations in individual cases as well as to advance the protection of human rights more broadly. This in-depth inquiry into civil society activism in the cases concerning gender and sexual identity will form a crucial basis for raising targeted plans and strategies addressing the potential restraints and strengthening its forces in working out effective social changes.   This socio-legal research, drawing upon the qualitative analysis of cases, quantitative analysis of data, desk-based research on multiple disciplines including feminist jurisprudence, criminology, and human rights, and qualitative analysis of primary data obtained through interviews, aims at shedding light on the relationship and interplay between the state and individual citizen, between power and rights, as well as between patriarchy and authoritarianism. It carries a special significance against the current backdrop that democracy and liberalism have been facing intensifying backlash in Europe and also globally.
The Large Sky Area Multi-Object Fiber Spectroscopic Telescope (LAMOST)

The Large Sky Area Multi-Object Fiber Spectroscopic Telescope (LAMOST, also called the Guo Shou Jing Telescope) is a special reflecting Schmidt telescope. LAMOST's special design allows both a large aperture (effective aperture of 3.6 m–4.9 m) and a wide field of view (FOV) (5°). It has an innovative active reflecting Schmidt configuration which continuously changes the mirror's surface that adjusts during the observation process and combines thin deformable mirror active optics with segmented active optics. Its primary mirror (6.67 m × 6.05 m) and active Schmidt mirror (5.74m × 4.40m) are both segmented, and composed of 37 and 24 hexagonal sub-mirrors respectively. By using a parallel controllable fiber positioning technique, the focal surface of 1.75 m in diameter can accommodate 4000 optical fibers. Also, LAMOST has 16 spectrographs with 32 CCD cameras. LAMOST will be the telescope with the highest rate of spectral acquisition. As a national large scientific project, the LAMOST project was formally proposed in 1996, and approved by the Chinese government in 1997. The construction started in 2001, was completed in 2008 and passed the official acceptance in June 2009. The LAMOST pilot survey was started in October 2011 and the spectroscopic survey will launch in September 2012. Up to now, LAMOST has released more than 480000 spectra of objects. LAMOST will make an important contribution to the study of the large-scale structure of the Universe, structure and evolution of the Galaxy, and cross-identification of multi-waveband properties in celestial objects.
AN IMPROVED DIRECTIONAL DRILLING TOOL

A directional drilling tool is provided, which comprises a first end (2) attachable to a drill string, and a second end (4) attachable to a drill bit. A swivel section (6) is provided intermediate the first and second ends (2,4) and has a first swivel member (18) non-rotatably attached to the first end (2) and a second swivel member (20) rotatably coupled to the first swivel member (18) and rotatable relative thereto about a first axis of rotation which is co-axial with a longitudinal axis (LI) of the tool. A first actuator is adapted to selectively rotate the second swivel member (20) about the first axis of rotation. An adjustable bend section (12) has a first bend member (118) non-rotatably attached to the second swivel member (20) and a second bend member (120) rotatably coupled to the first bend member (118), where the first bend member (118) is co-axial with the longitudinal axis (LI), and the second bend member (120) is rotatable relative to the first bend member (118) about a second axis of rotation (R) which is at a non-zero angle relative to the longitudinal axis (LI). A second actuator is adapted to selectively rotate the second bend member (120) about the second axis of rotation (R). A directional drilling system incorporating the tool, a control process for the tool, and a motor drive for rotating a second body relative to a first body are also provided.
Density functional theory for modelling large molecular adsorbate–surface interactions: a mini-review and worked example

AbstractFirst-principles simulation has played an ever-increasing role in the discovery and interpretation of the chemical properties of surface–adsorbate interactions. Nevertheless, key challenges remain for the computational chemist wishing to study surface chemistry: modelling the full extent of experimental conditions, managing computational cost, minimising human effort in simulation set-up and maximising accuracy. This article introduces new tools for streamlining surface chemistry simulation set-up and reviews some of the challenges in first-principles, density functional theory (DFT) simulation of surface phenomena. Furthermore, we provide a worked example of Co tetraphenylporphyrin on Au(1 1 1) in which we analyse electronic and energetic properties with semi-local DFT and compare to predictions made from hybrid functional and the so-called DFT+U correction. Through both review and the worked example, we aim to provide a pedagogical introduction to the challenges and the insight that first-princi...
Decisions of Recovery Processing and Service for Remanufacturing Supply Chains Based on Transaction Pricing

A remanufacturing supply chain consisting of a manufacturer and a third party recycling company is investigated. The third party recycling company provides recovery processing service and some other service for the manufacturer. Firstly, a Stackelberg game model is developed for recovery processing service. The pricing, processing conversion rate, recycling effort level and some other decisions are analyzed. Later, the influence of value-added service is discussed. The results show that: higher recycling payment of the manufacturer can encourage recycling behavior of the recyclers. The manufacturers which the detachable processing level of their products is high are more willing to accept related value-added services of recyclers. The high basic payment of manufacturers is the necessary condition to motivate the recycling service behavior of the recyclers; otherwise, recyclers may get slack in the process of recycling.
Development of an industrial robot

The object of the project is the development of an industrial robot – a single-purpose machine – used for inserting semi-finished products and subsequently removing products from the working space of the lathe without regular intervention of the operator. The industrial robot will meet the following requirements and parameters:- a simple concept of robot movement from point A to point B- the minimum space of the robot in the machine- the operator’s work safety with clearly defined and mechanically limited robot movements- the weight of the embedded semi-finished fabric up to 10 kg a.
Thinning and in-stream wood recruitment in riparian second growth forests in coastal Oregon and the use of buffers and tree tipping as mitigation

Many aquatic habitats in coastal Oregon have been impacted by historic land use practices that led to losses of in-stream wood and associated degraded fish habitats. Many of these streams are now bordered by stands of dense second growth forests (30–80 years) that are incorporated into riparian buffer zones with low wood recruitment and storage. Thinning in riparian zones is one management option to increase the rate of large tree growth and eventually larger in-stream wood, however, it raises concern about impacts on current wood recruitment, among other issues. Using a forest growth simulation model coupled to a model of in-stream wood recruitment, we explore riparian management alternatives in a Douglas-fir plantation in coastal Oregon. Alternatives included: (1) no treatment, (2) single and double entry thinning, without and with a 10-m buffer, and (3) thinning combined with mechanical introduction of some portion of the thinned trees into the stream (tree tipping). Compared to no treatment, single and double entry thinning on one side of a channel, without a 10-m buffer, reduce cumulative in-stream wood volume by 33 and 42 %, respectively, after 100 years (includes decay). Maintaining a 10-m buffer reduces the in-stream wood loss to 7 % (single entry thin) and 11 % (double entry). To completely offset the losses of in-stream wood in a single entry thin (on one or both sides of the stream), in the absence or presence of a 10-m buffer, requires a 12–14 % rate of tree tipping. Relative to the no-treatment alternative, cumulative in-stream wood storage can be increased up to 24 % in a double-entry thin with no buffer by tipping 15–20 % of the thinned trees (increased to 48 % if thinning and tipping simultaneously on both sides of the stream). The predicted increases in in-stream wood that can occur during a thin with tree tipping may be effective for restoring fish habitat, particularly in aquatic systems that have poor habitat conditions and low levels of in-stream wood due to historic land use activities.
Cefiderocol- Compared to Colistin-Based Regimens for the Treatment of Severe Infections Caused by Carbapenem-Resistant Acinetobacter baumannii

Cefiderocol may represent a therapeutic option for carbapenem-resistant Acinetobacter baumannii (CRAB) infections, but clinical data are limited. This is an observational retrospective study conducted in the University Hospital of Pisa including consecutive patients with CRAB infections (January 2020 to August 2021). Patients were divided in two study groups according to the antibiotic treatment received: cefiderocol- and colistin-containing regimens. The primary outcome was the 30-day mortality. A Cox regression analysis was performed to identify factors independently associated with 30-day mortality. A propensity score analysis using inverse probability of treatment weighting (IPTW) was also performed. A total of 124 patients were included: 47 (37.9%) received cefiderocol, while 77 (62.1%) colistin-containing regimens. Overall, 79 (63.7%) patients had a bloodstream infection (BSI), 35 (28.5%) a ventilator-associated pneumonia (VAP) and 10 (8.1%) other infections. Thirty-day mortality was higher in patients receiving colistin- compared to those who received cefiderocol-containing regimens (55.8% versus 34%, P = 0.018). This difference was confirmed in patients with BSI, but not in those with VAP. On multivariable analysis, septic shock, SOFA score, and age were independently associated with 30-day mortality, while cefiderocol therapy was protective in an IPTW analysis (Hazard ratio 0.44, 95% confidence interval 0.22-0.66, P < 0.001). Nephrotoxicity was more common in the colistin group. Microbiological failure occurred in 17.4% of patients receiving cefiderocol versus 6.8% of those receiving colistin (P = 0.079). Among 8 cases in the cefiderocol group who experienced microbiological failure, 4 (50%) developed resistance to cefiderocol. Cefiderocol represents a promising therapeutic option in patients with severe CRAB infections. Randomized clinical trial in this specific patient population should confirm our findings.
Crosslocations in the mediterranean: rethinking the socio-cultural dynamics of relative positioning

The Mediterranean, a key socio-cultural, economic and political crossroads, has shifted its relative position recently, with profound effects for relations between the peoples associated with its diverse parts. Crosslocations is a groundbreaking theoretical approach that goes beyond current borders research to analyse the significance of the changes in relations between places and peoples that this involves. It does this through explaining shifts in the relative positioning of the Mediterranean’s many locations – i.e. the changing values of where people are rather than who they are. Approaches focusing on people’s identities, statecraft or networks do not provide a way to research how the relative value of ‘being somewhere in particular’ is changing and diversifying. 
The approach builds on the idea that in socio-cultural terms, location is a form of political, social, economic, and technical relative positioning, involving diverse scales that calibrate relative values (here called ‘locating regimes’). This means locations are both multiple and historically variable, so different types of location may overlap in the same geographical space, particularly in crossroads regions such as the Mediterranean. The dynamics between them alter relations between places, significantly affecting people’s daily lives, including their life chances, wellbeing, environmental, social and political conditions and status. 
The project will first research the locating regimes crossing the Mediterranean region (border regimes, infrastructures; digital technologies; fiscal, financial and trading systems; environmental policies; and social and religious structures); then intensively ethnographically study the socio-cultural dynamics of relative positioning that these regimes generate in selected parts of the Mediterranean region. Through explaining the dynamics of relative location, Crosslocations will transform our understanding of trans-local, socio-cultural relations and separations.
Shoulder- and Back-Muscle Activation During Shoulder Abduction and Flexion Using a Bodyblade Pro Versus Dumbbells

Context: The Bodyblade Pro is used for shoulder rehabilitation after injury. Resistance is provided by blade oscillations—faster oscillations or higher speeds correspond to greater resistance. However, research supporting the Bodyblade Pro’s use is scarce, particularly in comparison with dumbbell training. Objective: To compare muscle activity, using electromyography (EMG), in the back and shoulder regions during shoulder exercises with the Bodyblade Pro vs dumbbells. Design: Randomized crossover study. Setting: San Diego State University biomechanics laboratory. Participants: 11 healthy male subjects age 19–32 y. Intervention: Subjects performed shoulder-flexion and -abduction exercises using a Bodyblade Pro and dumbbells (5, 8, and 10 lb) while EMG recorded activity of the deltoid, pectoralis major, infraspinatus, serratus anterior, and erector spinae. Main Outcome Measures: Average peak muscle activity (% maximum voluntary isometric contraction) was separately measured for shoulder abduction and flexion in the range of 85° to 95°. Differences among exercise devices were separately analyzed for the flexed and abducted positions using 1-way repeated-measures ANOVA. Results: The Bodyblade Pro produced greater muscle activity than all the dumbbell trials. Differences were significant for all muscles measured (all P &lt; .01) except for the erector spinae during shoulder flexion with a 10-lb dumbbell. EMG activity for the Bodyblade Pro exceeded 50% of the MVIC during both shoulder flexion and abduction. For the dumbbell conditions, only the 10-lb trials approached this effect. Conclusions: Using a Bodyblade during shoulder exercises results in greater shoulder- and back-muscle recruitment than dumbbells. The Bodyblade Pro can activate multiple muscles in a single exercise and thereby minimize the need for multiple dumbbell exercises. The Bodyblade Pro is an effective device for shoulder- and back-muscle activation that warrants further use by clinicians interested in its use for rehabilitation.
PENGARUH KEPEMILIKAN MANAJERIAL, INSTITUSIONAL DAN PROPORSI DEWAN KOMISARIS INDEPENDEN PADA MANAJEMEN LABA

The purpose of this study was to determine the effect of managerial ownership, institutional ownership and the proportion of commissioners on earnings management. This research was conducted at all manufacturing companies in Indonesia Stock Exchange 2009-2013 period. The samples used as many as 33 companies from the population of 123 companies, through a purposive sampling method. The data collection is done by using the method of observation nonparticipant through the financial statements. The analysis technique applied is a technique of multiple linear regression analysis. The results show that partial managerial ownership, institutional ownership and the proportion commissioners significant negative effect on earnings management.
Enabling multifunctional plasmonics on hybrid artificial scale-integrated systems

Optical isolator, or optical diode, is a device, which allows the transmission of light in only one direction. They are used in fibre optic communication to prevent back reflections and improve signal-to-noise ratio.  The development of on-chip optical communications requires downscaling of optical components, e.g replacing optical fibres with nanoscale waveguides. The miniaturization of optical isolators is therefore a key step towards integrated photonic circuits. We approach this challenge by taking advantage of surface plasmon resonances that can squeeze light down to nanoscale dimensions. We combine plasmonic waveguides with ferroelectric and -magnetic materials that, in turn, break the space-inversion and time reversal symmetries to create non-reciprocal conditions for light propagation. The ferroelectric and magnetic materials provide us with an additional interesting advantage: their optical properties can be adjusted by applying external electric and magnetic fields, enabling active control over light in nanoscale. The proposed research project brings together the candidate’s expertise in plasmonics and the hosting group’s established knowledge in oxide thin films. This creates excellent conditions for training through research and knowledge transfer. We envision two significant outcomes: (i) demonstration of a proof-of-concept plasmonic isolator based on symmetry considerations and (ii) assessing the viability of using active oxide materials as tools to control plasmon propagation with external fields. The H2020 Innovation Union initiative strives to drive economic growth in the EU by innovation. In line with this strategy, we recognize that EMPHASIS offers ample potential for technological applications and include strategies to ensure that the potential can be realized.