SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Managing asthma in general practice

People with asthma should receive regular education and support in the primary care context, within an effective partnership between the patient and suitably trained health professionals. Structured asthma reviews should be carried out at least annually in primary care, and personalized asthma action plans should be implemented for all patients. Pharmacological management of asthma involves ensuring that treatment is prescribed at an appropriate level, with titration where necessary, and, importantly, health professionals should confirm that patients are adept at taking their inhaled medication. Clinicians should address factors influencing the patient's condition—such as passive smoking and smoking cessation—identify allergenic triggers, and make appropriate referrals for patients' whose conditions are difficult to treat. Comprehensive treatment and advice should be tailored to the patient's individual needs, taking into account pertinent issues, such as personal health beliefs and the reasons for non-ad...
Energy use and greenhouse gas emissions from wastewater treatment plants

Besides its great potential in controlling water pollution from different sources, wastewater treatment system generates significant amount of greenhouse gases. Hence, reducing the emission of greenhouse gases from the wastewater treatment plants is the major concern. The correct understanding and estimation of the greenhouse gases emitted from different points of the plant is essential to tackle this challenge. This research has attempted to evaluate and quantify the emissions of greenhouse gases, mainly carbon dioxide, methane and nitrous oxide from the wastewater treatment system. Anaerobic wastewater treatment is more environmental friendly treatment technology than aerobic treatment due to its low solids generation rate, low energy consumption and the production of a usable biogas. In this study, IPCC Guidelines for National Greenhouse Gas Inventories are followed for calculating GHG emissions from wastewater treatment plants. This paper discusses the GHG emissions for wastewater treatment and compares the environmental benefits and GHG contributions of anaerobic and aerobic treatment technologies.
Non-Intrusive flow distortion measurements within a turbofan intake

Short and slim aero-engine intake designs for very high bypass ratio configurations cause notable levels of unsteady distortions at the fan face especially under cross-wind or angle of attack operation during aircraft take-off. Such distortions can adversely affect the engine’s performance, operability, structural integrity and safety margin with potentially catastrophic consequences for the entire propulsion system. 
Current practices for aero-engine testing and certification rely on a low number of intrusive pressure measurements at the fan face to characterise the distortion levels. Given the known limitations of currently used methods (low spatial resolution, intrusive nature) the existing technologies are inadequate to reduce the risk on the development and certification of future novel systems.   
NIFTI aims to address this gap by demonstrating a non-intrusive technique to measure velocity fields across a plane located upstream of a large diameter fan of a high bypass ratio aero-engine which has never been achieved. This method will provide synchronous datasets across the measurement plane with at least one order of magnitude higher spatial resolution than current methods. The implementation will demonstrate a highly automated and flexible multi-camera system within a representative industrial test environment. A number of more advanced, non-intrusive measuring technologies will be assessed such as 3D PTV or Helium Filled Soap Bubbles (HFSB) to further enhance the outputs of the selected baseline solution. 
The experimental activities will be supported by numerical campaigns and advanced data processing and flow analysis methods that will be used to analyse the highly unsteady nature of the flow distortions that will be measured during NIFTI’s experimental campaigns. These outcomes will ultimately unlock the complex aerodynamics of closely coupled fan-intake systems and aid the development of novel design rules for future, stall-tolerant aero-engines.
Agency costs and the long-run performance of debt issuers

This study focuses on an agency cost explanation of the long-run performance of debt issuers based on debt issuance data in Malaysia during the period from January 2001 to October 2009. Long-run performance is measured by buy and hold abnormal return (BHAR), while growth opportunities (GO), managerial ownership (MO), ownership concentration (OC) and free cash flow (FCF) are adopted as proxies for agency costs. Using a linear regression method, this study finds that BHAR is positively influenced by GO and OC but negatively influenced by MO and FCF, which supports an agency cost explanation of capital structure. An improvement in the performance of debt issuers is found to be associated with the monitoring of debt by debt issuers. Debt issuers with more concentrated ownership and lower MO benefit from the issuance of debt through a reduction of agency costs.
PHYTOGLYCOGEN-BASED COMPOSITIONS, MATERIALS AND METHODS

The present invention provides methods for treating phytoglycogen-containing materials to generate phytoglycogen compositions with enhanced emulsiiication attribute. One method comprises contacting a phytoglycogen-containing material with at least one protease. The other method comprises heat treatment of a phytoglycogen-containing material, such as corn kernels. The two methods can be applied independently, or can be applied in combination. Applications of phytoglycogen compositions are also included.
Heavy ion collisions: collectivity and precision in saturation physics

The main goal of this project is to reinforce and expand a long-lasting collaboration network between research centers of excellence from EU and the USA aimed at addressing fundamental questions in the physics of dense systems produced in high energy collisions of proton-proton (pp), proton-nucleus (pA) and heavy-ion collisions (HICs). The greatest challenge is to understand whether the final state of such a collision (especially when the size of colliding objects is small) has a character of a genuine strongly interacting medium like Quark Gluon Plasma (QGP), or whether the observed characteristics (such as correlations between produced particles) can be explained by a non trivial quantum mechanical nature of the colliding objects due to saturation physics.
To meet this challenge we propose a two-pronged approach: on one hand a dedicated study of quantum mechanical effects in the environment of dense partonic  wave function in the saturation regime, and on the other a systematic improvement of the current quantitative approaches, based on Quantum Chromodynamics (QCD) and studying their phenomenological implications. These goals will be accomplished by means of joint research activities which will be developed through the mobility of individual researchers.

The main research objectives of the proposal are: 

A: Quantifying importance of quantum interference in correlated particle production, specifically concentrating on effects of saturation in the wave function of energetic proton on its quantum properties.

B: Development of a comprehensive theoretical framework to study saturation physics both at leading and next to leading orders in the QCD coupling constant.

C: Phenomenological description of saturation-sensitive observables in pp, pA and HICs.

D: Application of the results of the research to future projects, specifically electron-ion colliders under proposal in the US (the Electron-Ion Collider EIC) and at CERN (the Large Hadron-electron Collider LHeC ).
Developing Sustainable Process in Water Economy Using Social Media

The main idea developed here is how to involve people to promote a new behavior to economize water as supported by the local authorities process. Usually, the population is affected by the cities policies when they are subject to fines related to high water use during times of crisis. Then the local authorities impose solutions without consultations of concerned communities. This top-down process is often considered as imposed by the mayor or the local authority and may lead to bad feeling by the population and is not corresponding to a new societal behavior in the social web era. We will suggest a new way to involve the population using the social media as a new approach to imply them in this process. This information can be conveyed and shared with the public in such way to support mayor or authorities policies. In other way we will propose a new approach using social media processes as a node in the first hand to encourage the population to participate to the debate and to fit a new solution encouraging all population to get part of the policies adopted based on a bayesian approach.
(19474.04112021.194000199) CAKE STAR

THE HISTORY OF AN ANCIENT FOOD FACTORY TOSCANA SRL HAS ITS ROOTS IN 1932 AND NOW FOR FOUR GENERATIONS HAS BEEN IN THE MARKET WITH THE PRODUCTION OF SWEETS AND SPECIALTIES? OF THE ITALIAN TRADITION, TYPICAL PRODUCTS, AUTHENTIC AND HANDMADE. DO THE OWNERS CLAIM THAT EACH OF OUR CREATIONS? PART OF US? PART OF OUR STORY? THE CONFECTIONERY COMPANY HAS NOW CONQUERED AN IMPORTANT SLICE IN THE LOCAL MARKET THANKS TO ITS PRODUCTION ATTENTIVE TO THE USE OF RAW MATERIALS OF THE HIGHEST QUALITY? AND PROCEDURES IN LINE WITH THE TRADITION FROM WHICH IT DERIVES, BUT ALSO WITH A CAREFUL EYE TO THE TERRITORY, HEALTHY FOOD AND GENUINE LIFE THAT HAVE LED TO THE CREATION OF A LINE OF BISCUITS AND CERTIFIED ORGANIC SAVORY PRODUCTS, PRODUCED AT KM 0. THIS ATTENTION HAS LED THE COMPANY TO THE CREATION OF THE BRAND?VANNINOBIO?. THE AWARENESS OF THE OWNERS OF THE COMPANY AND THE DESIRE FOR GROWTH AND EXPORT OF QUALITY? OF ITS OWN PRODUCTION THAT HAS BEEN COLLECTED FOR YEARS
Abstract CT221: CHRONOS-3: A phase III, randomized, double-blind, placebo-controlled study evaluating the efficacy and safety of phosphatidylinositol-3 kinase (PI3K) alpha/delta inhibitor copanlisib in combination with rituximab in patients with relapsed indolent B-c

Background: Copanlisib is a novel pan-Class I PI3K inhibitor with potent preclinical inhibitory activity against both PI3K-δ and PI3K-α isoforms. In a phase II study of copanlisib monotherapy in patients with relapsed/refractory indolent or aggressive lymphoma, an overall response rate of 53% was seen in patients with iNHL (Dreyling et al., ENA 2014). Rituximab in combination with chemotherapy is standard first-line therapy for indolent iNHL and is a therapeutic option for relapsed patients who cannot tolerate chemotherapy or who had a long response following the last rituximab-based therapy. The objective of this study is to evaluate the efficacy and safety of copanlisib in combination with rituximab versus placebo plus rituximab in patients with iNHL who relapsed after one or more lines of therapy, including rituximab and alkylating agents, and who are either unfit for chemotherapy or had a treatment-free interval of at least 12 months following last rituximab-based therapy. Methods: Patients must meet the following criteria: histologically confirmed diagnosis of iNHL, with follicular lymphoma (FL) grade 1-2-3a, marginal zone lymphoma (splenic, nodal, or extra-nodal), small lymphocytic lymphoma, or lymphoplasmacytoid lymphoma/Waldenstrom macroglobulinemia, and who have previously received at least one line of therapy including rituximab and alkylating agents. Patients must be not refractory to rituximab during any prior line of therapy (response Citation Format: Pier Luigi Zinzani, John F. Gerecitano, Marius Giurescu, Rodrigo Ito, Katharina Mueller, Barrett H. Childs. CHRONOS-3: A phase III, randomized, double-blind, placebo-controlled study evaluating the efficacy and safety of phosphatidylinositol-3 kinase (PI3K) alpha/delta inhibitor copanlisib in combination with rituximab in patients with relapsed indolent B-c [abstract]. In: Proceedings of the 106th Annual Meeting of the American Association for Cancer Research; 2015 Apr 18-22; Philadelphia, PA. Philadelphia (PA): AACR; Cancer Res 2015;75(15 Suppl):Abstract nr CT221. doi:10.1158/1538-7445.AM2015-CT221
Integrated evaluation methods to hbim for the management of cultural heritage: the case study of the colonnade of patio de Los Leones, Alhambra-Granada

Historical heritage plays a fundamental role in society. One of the primary targets for European countries is to ensure its safeguarding so that it can be enjoyed by future generations. This paper defines a procedure for the safeguarding of cultural heritage which is often in an advanced state of degradation and threatened by climate change and the increasing number of tourists. The methodology consists of three basic steps: the identification of the technical elements on which intervention is necessary, the assessment of the vulnerability level of these elements considering exogenous factors and the hierarchization of the most vulnerable elements through the application of the Analytic Hierarchy Process. The case study is the “Patio de los Leones” a world-famous site within the Alhambra and Generalife which every year attracts over 2 million tourists to Granada, Spain. The aim is to set priorities for intervention on the 124 “Macael” marble columns according to the need for restoration. The validation of the methodology and management of the data to achieve the hierarchy among the columns was done using an HBIM model. Il patrimonio storico culturale ha un ruolo fondamentale dal punto di vista sociale. Uno degli obiettivi primari per i paesi europei è quello di garantirne la salvaguardia per consentirne la fruizione alle generazioni future. In questo articolo si definisce una procedura utile alla conservazione di tale patrimonio che spesso verte in condizioni di degrado molto avanzate e che i cambiamenti climatici ed il crescente numero di turisti mettono ulteriormente a rischio. Nello specifico, la metodologia consta di tre passaggi fondamentali: l’individuazione degli elementi tecnici sui quali è necessario un intervento, la valutazione del livello di vulnerabilità di tali elementi tenendo conto dei fattori esogeni e delle caratteristiche morfologiche e di localizzazione, e la gerarchizzazione degli elementi maggiormente vulnerabili attraverso l’applicazione dell’Analytic Hierarchy Process. Il caso applicativo, è il “Patio de los Leones”, sito di fama mondiale all’interno dell’Alhambra e del Generalife, che attira a Granada, in Spagna, oltre 2 milioni di turisti ogni anno. Il fine, nel caso studio, è quello di definire le priorità d’intervento sulle 124 colonne in marmo di “Macael” che necessitano di delicati interventi di restauro. La verifica della metodologia, l’archiviazione e gestione dei dati per giungere alla gerarchizzazione degli interventi di restauro è stata fatta attraverso un modello HBIM
Sustainable Management of Coastal Areas

The first objective of this projects concerns the protection and the evaluation of coastal areas along the Adriatic Sea. There will be carry out studies about the variations of the territorial and environmental assessment of the Adriatic coasts; about geology, morphology and ecology of the specific areas; about the experimentation of alternative solutions for the improvement of the integrated energetic sources and about the possibilities to obtain certification of environmental management systems. The plan looks at the national Adriatic coast, with particular regard to the Molise and Abruzzi regions, and at the frontal coasts beyond the sea, with particular regard to the countries of the Albania, Croatia and Bosnia and Herzegovina coasts.
Effects of land tenure and protected areas on ecosystem services and land use preferences in Norway

Prior research has examined the relationship between physical landscapes and ecosystem services, but the distribution of ecosystem services by land tenure and protected areas is less developed. We analyze the spatial distribution of participatory mapped ecosystem values, as indicators of ecosystem services, to determine their relationship with land tenure in southern Norway, a region characterized by private, village, and state commons lands overlaid with designated protected areas managed by local governments. We found land tenure to be a significantly stronger predictor of the distribution of ecosystem values and land use preferences than protected area status. Protected area designations layered on older land tenures exert relatively little influence on how Norwegians perceive ecosystem values and land use preferences. The exception is a few iconic parks located on state commons where participants mapped a higher proportion of biological diversity and undisturbed, natural qualities. Hunting and fishing opportunities were especially important in village commons, whereas social interactions, gathering, and cultural identity clustered near settlements on private lands. The cultural ecosystem values of recreation and scenery were most frequently identified, but were unrelated to both land tenure and protected areas. Cabins, tourism development, and snowmobile use were important land uses to regional residents and most controversial in the commons and protected areas, but the overall potential for land use conflict appears highest on private land. Participants mapped preferences to increase predator control across all tenures reflecting the strong interest in large game hunting and livestock grazing in the region. Overlapping tenures that were in place before the designation of protected areas are important for understanding conservation effectiveness and the potential for land use conflict.
Método de fabricação de fibras finas, meio de filtragem e elemento de filtragem

fibras finas feitas a partir de aditivos de reação. a presente invenção refere-se ao material de fibra fina única que é formado a partir de um material de polímero de formação de fibras com pelo menos dois aditivos de reação que são capazes de reagir uns com os outros, e opcionalmente fazendo reagir com o polímero de formação de fibra.
Living architecture

Living Architecture (LIAR) is a modular bioreactor-wall, which is based on the operational principles of microbial fuel cell technology and synthetic ‘consortia’ of microbes. LIAR is conceived as a next-generation selectively-programmable bioreactor and integral component of human dwelling, capable of extracting valuable resources from waste water and air, generation of oxygen and production of  proteins and fiber by manipulating consortia performance. Its operational principles are grounded in distributed sensing, decentralised autonomous information processing, high-degree of fault-tolerance and distributed actuation and reconfiguration. Applications within urban systems are examined as a form of customizable micro-agriculture for installation in domestic, public (schools, hospitals) and office environments. Such a system has far reaching impacts on the building performance (resilience, resource recycling) manufacturing and design with ecosystems.

The project establishes: 

• Foundational concepts through which ‘designed’ metabolisms can computationally process, recycle, remediate and synthesise valuable compounds from waste water. 

• Transferable principles by which synthetic ecosystems can shape the environmental performance of our living spaces to increase our health, productivity and ecosystems impact.

• New standards for synthetic ‘ecosystems’ through consortia design, engineering and optimization.
3M™ Petrifilm™ Environmental Listeria Plate

Abstract A validation study of the 3M™ Petrifilm™ Environmental Listeria (EL) Plate (3M Food Safety, St. Paul, MN) was conducted at Q Laboratories, Inc., Cincinnati, OH. The method was compared to the Health Canada MFHPB-30 reference method for the analysis of stainless steel environmental surfaces. Twenty replicates of the environmental surface were analyzed at a low and a high inoculum level. The low-level sampling area was inoculated with 0.2–2 CFU/5 cm2, and the high-level sampling area was inoculated with 2–5 CFU/5 cm2. Five control replicates were also analyzed at 0 CFU/5 cm2. There was no significant difference in the number of positives detected by the 3M Petrifilm EL Plate method and the Health Canada MFHPB-30 reference method for the environmental surface analyzed in this study.
Industrial production of stable fibroblast growth factors for broad therapeutic, research, and  personal care applications

Our business concept focuses on development and marketing of stable fibroblast growth factors (FGFs) for medical, personal care and research use. FGFs are currently being tested therapeutically for use in cancer treatment, regenerative medicine, as well as in cosmetics. The FGF-based therapeutic approaches contribute towards promoting active and healthy ageing, which is a societal challenge common to all European countries. Another important application of FGFs is in the highly attractive cancer stem cell research with the extension to clinical applications. FGFs are being used as an essential reagent ensuring that stem cells are kept in the undifferentiated state. However, FGF instability is one of the major bottlenecks preventing wider use of FGFs. The FGFSTAB project will address this instability by computer-assisted design of multiple stabilizing mutations combined with cutting-edge molecular biology techniques. The expected outcomes of the project will be a universal protein engineering platform for designing stable FGFs and the process for manufacturing of stable FGFs that are not commercially available, even though there is a huge market for them. Added value of our innovation compared to existing solutions will be unprecedented stability, dramatic production cost reductions and the absence of harmful additives. Such FGFs will have much broader applicability than currently used natural molecules. Because of the wide range of products based on FGFs nowadays, we expect that the outcomes of the project will help us to access new high-value markets addressing global societal challenges, such as health care, bio-research, and personal care. All these market segments are characterized by the considerable size, growth and potential impact on people’s everyday lives. The phase 1 of the SME instrument will allow us to carry out well-researched feasibility study which will help us to take our business forward with confidence, and ultimately, increase our bottom line.
Sewerage And Waste Water Treatment in the Adriatic Coastal Area: development of an adequate tool on project development

The main objective of the SAWWTACA project is the improvement and harmonisation of policies and actions aimed at upgrading sewerage networks and wastewater treatment in urban settlements around the Adriatic Sea. The project will, in the first place, create a durable network of local authorities and experts. The network targets a continuous upgrading of the overall awareness and know-how on safeguarding Adriatic surface water by improving sewerage systems and wastewater treatment, being a platform for exchange of experiences and transfer of knowledge on innovative technologies and management tools. Secondly, an innovative tool will be developed, elaborated as a set of guidelines, which should enable local authorities to identify which infrastructure investments are needed, how to implement them, which restrictions and standards follow from national and Community legislation, and which technologies are most suitable to use. In order to meet the specific needs of the Adriatic area, a thorough analysis of the state of the art on sewerage and wastewater treatment in Adriatic coastal regions will be carried out. Said analysis will be confronted with local experiences and expertise available within the partnership, resulting in a Master Plan for the Adriatic area, which will serve as a reference for policy development in the Adriatic area. With this background information, the final guidelines on project development in sewerage and wastewater treatment in the Adriatic area will be elaborated.