SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Gail Hastings: Sculptuations

What first draws me to Gail Hastings's work is her accomplished hand and the alluring quality of her watercolours into which she incorporates text both earnest and ironic, playful and engaging. Her application of watercolour and pencil on rag paper is executed with aesthetic rigour; the careful way she loads her brush and renders text and structure is captivating. The watercolours articulate space, and invite the viewer in. They are like thoughts that are rooms with walls that we enter conceptually. As thought, this presence accompanies the viewer from room to room. A plot unfolds, then turns back on itself: it is poetic, witty and always visually accomplished.
In Vivo Imaging of GLP-1R with a Targeted Bimodal PET/Fluorescence Imaging Agent

Accurate visualization and quantification of β-cell mass is critical for the improved understanding, diagnosis, and treatment of both type 1 diabetes (T1D) and insulinoma. Here, we describe the synthesis of a bimodal imaging probe (PET/fluorescence) for imaging GLP-1R expression in the pancreas and in pancreatic islet cell tumors. The conjugation of a bimodal imaging tag containing a near-infrared fluorescent dye, and the copper chelator sarcophagine to the GLP-1R targeting peptide exendin-4 provided the basis for the bimodal imaging probe. Conjugation was performed via a novel sequential one-pot synthetic procedure including (64)Cu radiolabeling and copper-catalyzed click-conjugation. The bimodal imaging agent (64)Cu-E4-Fl was synthesized in good radiochemical yield and specific activity (RCY = 36%, specific activity: 141 μCi/μg, >98% radiochemical purity). The agent showed good performance in vivo and ex vivo, visualizing small xenografts (<2 mm) with PET and pancreatic β-cell mass by phosphor autoradiography. Using the fluorescent properties of the probe, we were able to detect individual pancreatic islets, confirming specific binding to GLP-1R and surpassing the sensitivity of the radioactive label. The use of bimodal PET/fluorescent imaging probes is promising for preoperative imaging and fluorescence-assisted analysis of patient tissues. We believe that our procedure could become relevant as a protocol for the development of bimodal imaging agents.
From monuments to cultural landscapes: Rethinking heritage management in Botswana

This thesis aims to understand how Manonnye Gorge in eastern Botswana can be sustainably managed as both a natural and cultural landscape. At issue are conflicting views over the meaning and legitimate uses of the Gorge by the National Museum, Monuments and Art Gallery (NMMAG), tourists, and the community in Moremi, at the edge of the gorge. Regional survey in the gorge and ethnographic research with the Moremi community led to a more complex understanding of how conflicting perceptions of the gorge as a sacred cultural landscape by community members and as a natural monument by NMMAG have affected implementation of ecotourism projects. The thesis critiques the idea of the gorge as simply a natural monument and provides recommendations for reassessing management plans and ecotourism projects.
Overexpression of acetyl-coenzyme A carboxylase beta increases proinflammatory cytokines in cultured human renal proximal tubular epithelial cells

We have identified the acetyl-coenzyme A carboxylase beta gene (ACACB) as a strong susceptibility gene to diabetic nephropathy in individuals with type 2 diabetes. To elucidate the mechanism by which ACACB contributes to conferring susceptibility to diabetic nephropathy, we examined the role of ACACB in human renal proximal tubular epithelial cells (RPTECs).RPTECs were infected with adenovirus vectors encoding ACACB or LacZ (control), and messenger RNA (mRNA) expression profiles were evaluated with a microarray analysis. We determined the mRNA expressions of proinflammatory cytokines by real-time quantitative reverse transcription (RT) polymerase chain reaction (PCR) and secretion of these cytokines from cells by enzyme-linked immunosorbent assay (ELISA).Among 54,613 transcripts analyzed in the microarray analysis, genes encoding proinflammatory cytokines, including interleukin (IL)-6, chemokine (C-X-C motif) ligands (CXCL) 1, 2, 5, and 6, were remarkably up-regulated (>20-fold) in the ACACB-overexpressing cells. The increased expression of these inflammatory cytokines was reversed by the addition of a synthetic inhibitor of acetyl-coenzyme A carboxylase beta. Overexpression of ACACB could increase IL-6 mRNA expression and IL-6 protein secretion in a time-dependent manner. We further found that IL-6 mRNA stability and expression had significantly increased in ACACB-overexpressing RPTECs, and a treatment of the cells with p38 mitogen-activated protein kinase (MAPK) inhibitor partially but significantly reversed these effects.An excess of ACACB results in increased proinflammatory cytokine expression, such as IL-6, at least partly by increasing mRNA stability through a p38 MAPK-dependent pathway.
Transformers: Changing the face of nursing and midwifery in the media

This paper reports an educational strategy designed to sensitise and empower students about the impact of media representations of nursing and midwifery on their public image.Numerous studies continue to reveal that stories about nursing and midwifery presented in the mainstream media are often superficial, stereotypical and demeaning. Inaccurate portrayals of nursing damage our professional reputation with the public and potential consumers. It also sends the wrong message to future nursing students. Images are a powerful conductor of misinformation, suggesting to others that nurses are not important agents for social change.In 2012, a small team of academics designed a photography competition and judging process for undergraduate and postgraduate students of nursing and midwifery enrolled at a regional Australian university.The winning entries were photographs of high quality and conveyed rich meaning. They provide an interesting and positive counterpoint to derogatory images often propagated by mainstream media.There is benefit in extending this project so that it: appeals to more students, builds leadership skills, leads to wider social change and benefits society. The intention is to develop the process of student engagement as an educational intervention, and explore experiences and outcomes with stakeholders.
El legado de Le Corbusier como materia genética de proyecto en la obra de OMA

Para todo crítico de la obra del célebre arquitecto holandés, la influencia de Le Corbusier es un hecho innegable. Una de sus primeras obras construidas, la Villa Dall’Ava, funciona como punta de lanza de un diálogo continuo, por momentos casi sacrílego, con una de las viviendas más emblemáticas del Movimiento Moderno, la Villa Savoye. Sin embargo, aparte de la mera manipulación de los cinco puntos basada en una lógica ligada al surrealismo daliniano, los documentos del archivo de OMA relacionados con este proyecto muestran que las apropiaciones van más allá de una irreverente mutación de los elementos más caricaturales del discurso lecorbusieriano. En este sentido, el trabajo de OMA se desarrolla como una herramienta de análisis crítico del verdadero carácter del movimiento moderno, pero, sobre todo, como la exploración continua de una serie de estrategias y problemáticas compartidas con la obra de Le Corbusier, recontextualizadas en un marco contemporáneo.
Club Portogallo Esportatore

Il CLUBE PORTUGAL exportador consiste in un piano di promozione esterno da realizzare nel 2017 e nel 2018, inserito in una strategia volta ad un ampio ambito di intervento che riunisce un certo numero di PMI che condividono lo stesso profilo di esportazione coprendo fiere e missioni in vari mercati internazionali.
Commercial monopoly management of Japanese commercial firms during the War of Resistance Against Japan in Anhui

During the War of Resistance Against Japan,Japanese Army put into effect the policy of economic control in the area of Centre China and so on for the aim of developing war by using war,and set up the commercial firms for pillaging sources and dumpping goods.In the enemy-occupied area of Anhui,Japanese Army set up the commercial firms widely,push aside the Chinese merchants,monopolied the trade,carried out sharing sell for residents and shops,appointed the Japanese commercial firms buy all the grain for the army and so on,formed various commercial firms purchase organizations for monopolizing commerce.The forms of its commercial monopoly management were various,its endangerment was very serious,disrupted market order,production and lives of people deeply in the enemy-occupied area.
Rates of accumulation of cadmium and uranium in a New Zealand hill farm soil as a result of long-term use of phosphate fertilizer

Abstract In New Zealand, phosphate (P) fertilisers used in agriculture are the main sources of the potentially toxic elements cadmium (Cd) and uranium (U), which occur as unwanted contaminants. New Zealand is developing draft soil guideline values (SGV) for maximum concentrations of Cd. To assess when soils under pasture for sheep production might reach a particular SGV, we analysed archived soil samples from a 23 yr P fertiliser trial. The pasture sites were at Whatawhata, North Island, New Zealand, and had received P fertiliser at the rates of 0, 30, 50 and 100 kg P ha−1 yr−1. From 1983 to 1989, P was applied as single superphosphate, from 1989 to 2006, P was applied as triple superphosphate. Soils from replicate paddocks were sampled annually to a depth of 75 mm on easy (10–20°) and steep (30–40°) slope classes. Total P, Cd and U were analysed by ICP-MS after acid digestion. Data were analysed by fitting trend lines using linear mixed models for two slope classes and for two sampling periods 1983–1989 and 1989–2006 when the soil sampling method and fertiliser type had been changed. The changes in total P, Cd and U were directly related to the type and amount of P fertiliser applied, the control treatment showed no significant change in P, Cd or U. At 50 and 100 kg P ha−1 yr−1 there were generally linear increases in total P and total U, and the same trend line applied to both time periods, but the rate of increase in P was greater on the easy slope class. For Cd, a “broken stick” model was needed to explain the data. Pre-1989, Cd increased in the 50 and 100 kg P ha−1 yr−1 treatment (0.036–0.045 mg kg−1 yr−1, respectively): post 1988 the rate of increase declined markedly on those two treatments (0.005–0.015 mg kg−1 yr−1, respectively), and declined absolutely in the 30 kg P ha−1 yr−1 treatments. The maximum content of Cd was in the 100 kg P ha−1 yr−1 treatment which reached 0.931 mg Cd kg−1 on the easy slope. For U there were steady linear increases for the 30, 50 and 100 kg P ha−1 treatments, and no significant difference between the steep and easy slopes, nor the two sampling periods, the maximum concentration obtained was 2.80 mg U kg−1 on the 100 kg P ha−1 treatment. The results suggest that at rates of P fertiliser likely to be applied to hill farms (
Chiral Forces Organize Left-Right Patterning in C. elegans by Uncoupling Midline and Anteroposterior Axis

Left-right (LR) patterning is an intriguing but poorly understood process of bilaterian embryogenesis. We report a mechanism for LR patterning in C. elegans in which the embryo uncouples its midline from the anteroposterior (AP) axis. Specifically, the eight-cell embryo establishes a midline that is tilted rightward from the AP axis and positions more cells on the left, allowing subsequent differential LR fate inductions. To establish the tilted midline, cells exhibit LR asymmetric protrusions and a handed collective movement. This process, termed chiral morphogenesis, involves differential regulation of cortical contractility between a pair of sister cells that are bilateral counterparts fate-wise and is activated by noncanonical Wnt signaling. Chiral morphogenesis is timed by the cytokinetic furrow of a neighbor of the sister pair, providing a developmental clock and an unexpected signaling interaction between the contractile ring and the adjacent cells.
TRANSFORMASI LINTAS GENRE: DARI NOVEL KE FILM, DARI FILM KE NOVEL

This article is aimed at scrutinizing the ecranisation in the transformation across genre, that is from novels to films, and vice versa. It was found that the ecranisation process from novels to films is a process envolving the reactualisation from the written language to the audio visual language. The implication of that process is that there are some efforts to shrink, add, or alter parts of the story for various goals. Seen from the perspective of the sociology of literature, this effort could initiate the low reading motivation to the high watching motivation. In the context of aesthetic idealism, ecranisation actually exposes an author’s depression due to his lack of ability to articulate his audio visual language in representing the written language. In contrast, films has been de-ecranised into novels. An across genre transformation process is thus made, that is from the audio visual tradition, wrapped by advanced technology, to the reading-writing tradition. The latter tradition phenomena is different from the former, specifically in its perspective of the social function of literature. Unfortunately, both cannot avoid the hegemony of industrialisation. Literature and films are no more concerned with easthetic values. Rather they mingle in industrialisation, in particular the entertainment industry.
7-Substituted pterins provide a new direction for ricin A chain inhibitors

Ricin is a potent toxin found in castor seeds. The A chain, RTA, enzymaticlly depurinates a specific adenosine in ribosomal RNA, inhibiting protein synthesis. Ricin is a known chemical weapons threat having no effective antidote. This makes the discovery of new inhibitors of great importance. We have previously used 6-substituted pterins, such as pteroic acid, as an inhibitor platform with moderate success. We now report the success of 7-carboxy pterin (7CP) as an RTA inhibitor; its binding has been monitored using both kinetic and temperature shift assays and by X-ray crystallography. We also discuss the synthesis of various derivatives of 7CP, and their binding affinity and inhibitory effects, as part of a program to make effective RTA inhibitors.
Analyte quantification with comprehensive two-dimensional gas chromatography: Assessment of methods for baseline correction, peak delineation, and matrix effect elimination for real samples

Comprehensive two-dimensional gas chromatography (GC×GC) is used widely to separate and measure organic chemicals in complex mixtures. However, approaches to quantify analytes in real, complex samples have not been critically assessed. We quantified 7 PAHs in a certified diesel fuel using GC×GC coupled to flame ionization detector (FID), and we quantified 11 target chlorinated hydrocarbons in a lake water extract using GC×GC with electron capture detector (μECD), further confirmed qualitatively by GC×GC with electron capture negative chemical ionization time-of-flight mass spectrometer (ENCI-TOFMS). Target analyte peak volumes were determined using several existing baseline correction algorithms and peak delineation algorithms. Analyte quantifications were conducted using external standards and also using standard additions, enabling us to diagnose matrix effects. We then applied several chemometric tests to these data. We find that the choice of baseline correction algorithm and peak delineation algorithm strongly influence the reproducibility of analyte signal, error of the calibration offset, proportionality of integrated signal response, and accuracy of quantifications. Additionally, the choice of baseline correction and the peak delineation algorithm are essential for correctly discriminating analyte signal from unresolved complex mixture signal, and this is the chief consideration for controlling matrix effects during quantification. The diagnostic approaches presented here provide guidance for analyte quantification using GC×GC.
CENTRIFUGAL PENDULUM AND DRIVE ARRANGEMENT FOR A MOTOR VEHICLE

The invention relates to a centrifugal pendulum for damping torsional vibrations and to a drive arrangement for a motor vehicle which includes the centrifugal pendulum according to the invention. The centrifugal pendulum comprises at least one pendulum flange (20), which is rotatable about a rotation axis (1), and multiple pendulum masses (10), which are mounted displaceably on the pendulum flange (20), each for executing a vibration movement (2) running substantially perpendicular to the rotation axis, the centrifugal pendulum having a friction sleeve (40) for each pendulum mass (10), and each friction sleeve (40) being connected fixedly in an interlocking manner to the associated pendulum mass (10). The centrifugal pendulum according to the invention has a long service life and can efficiently reduce or eliminate torsional vibrations, particularly in the drive trains of motor vehicles driven by internal combustion engine.
Flue Gas CO2 Mineralization Using Thermally Activated Serpentine: From Single- to Double-step Carbonation

Abstract This communication explores the carbonation potential of activated serpentine at flue gas conditions. A first series of single-step batch experiments was performed varying the temperature and the slurry density to systematically assess the precipitation regime of the relevant Mg-carbonates and the fate of the Si species in solution. The results suggested that the reaction progress was hindered by a passivating layer of re-precipitated silica, quartz, or carbonates, as well as by equilibrium limitations. Among several strategies that were tested to overcome these limitations, a simple double-step process that is driven by a temperature swing in combination with a low-level CO2 pressure swing is presented. Exploratory experiments are shown that prove the viability of our process, first by applying a discontinuous method, and secondly by implementing a methodology to cycle the liquid phase continuously between a dissolution reactor and a precipitator. In this way, it was possible to produce highly pure Mg-carbonates that may serve various industries.
A BEAM CLAMP, AND A MOUNTING ASSEMBLY

A beam clamp for attachment to a flange of a structural building member and from which to support or brace a service component. The beam clamp has a clamp body, and a set screw. The clamp body includes a first jaw section with at least one mounting through hole, a second jaw section, a joining section that interconnects the first and second jaw sections, and a transverse opening that is to receive the flange. A contact surface on the second jaw section is formed with surface irregularities providing a roughness that enhances engagement of the contact surface with the flange. In use of the beam clamp, the contact surface is in contact with the flange of the structural member, the set screw is installed in the mounting through hole, and the flange is secured within transverse opening between the tip of the set screw and the contact surface.
A model checking method for the proportional hazards model with recurrent gap time data

Recurrent events are the natural outcome in many medical and epidemiology studies. To assess covariate effects on the gaps between consecutive recurrent events, the Cox proportional hazards model is frequently employed in data analysis. The validity of statistical inference, however, depends on the appropriateness of the Cox model. In this paper, we propose a class of graphical techniques and formal tests for checking the Cox model with recurrent gap time data. The building block of our model checking method is an averaged martingale-like process, based on which a class of multiparameter stochastic processes is proposed. This maneuver is very general and can be used to assess different aspects of model fit. Numerical simulations are conducted to examine finite-sample performance, and the proposed model checking techniques are illustrated with data from the Danish Psychiatric Central Register.
Reassessing late ottoman literatures within a mediterranean framework

Arslan’s project proposes a new paradigm for studying late Ottoman literatures that were written in the nineteenth and early twentieth century and in different languages such as Arabic, Ottoman Turkish, and French by situating these literatures in a multilingual and multicultural Mediterranean framework instead of their respective national communities. His project will build upon three dimensions that constitute the objectives of his study. (i) The history dimension will map out literary and cultural exchanges within the nineteenth-century and early twentieth-century Mediterranean through archival research and digital humanities techniques. (ii) The criticism dimension will demonstrate that thematic preoccupations of Mediterranean literatures—including but not limited to diaspora, travel, imperialism, cultural hybridity, and fluidity of borders and identities—were also defining characteristics of late Ottoman literatures via a close reading of canonical late Ottoman works. (iii) The theory dimension will draw upon the latest debates in postcolonial studies, migration and diaspora studies, and world literature to examine how the Mediterranean can be used as a category of analysis in cultural and literary studies. Building upon these three objectives, Arslan’s project will put two fields—Mediterranean studies and Ottoman studies—in dialogue with each other to generate a disciplinary transformation of both, while undermining the ways in which late Ottoman literatures have been categorised and studied. Having just finished his Ph.D., Arslan hopes to have an advantageous start at his career by the end of this fellowship through completing a substantial portion of a sole-authored monograph, publishing peer-reviewed articles and policy briefs, organising conference panels and communication activities, and joining networks of scholars in North Africa, Europe, and the Middle East who work on Mediterranean and Ottoman studies.
Ore Deposit Geology

Mapping closely to how ore deposit geology is now taught, this textbook systematically describes and illustrates the major ore deposit types, linking this to their settings in the crust and the geological factors behind their formation. Written for advanced undergraduate and graduate students with a basic background in the geosciences, it provides a balance of practical information and coverage of the relevant geological sciences, including petrological, geochemical, hydrological and tectonic processes. Important theory is summarized without unnecessary detail and integrated with students' learning in other topics, including magmatic processes and sedimentary geology, enabling students to make links across the geosciences. Students are supported by further reading, a comprehensive glossary, and problems and review questions that test the application of theoretical approaches and encourage students to use what they have learnt. A website includes visual resources and combines with the book to provide students and instructors with a complete learning package.