SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Influence of bark on the mapping of mechanical strain using digital image correlation

Stereoscopic photogrammetry digital image correlation systems (DIC) are being used to remotely measure deformation and movement in a number of industrial research programs. The incorporation of DIC into ecology, forestry or arboricultural research can help understand how trees and other plants react during static or dynamic biomechanical trials. In the case of deformation, DIC systems map strain which will help understand how a load is transferred from one section of tree to another (i.e., from a branch to the central stem). DIC often utilizes a stochastic paint speckling (contrasting black on white) to create a series of reference points that can be tracked during testing to map strain. During previous field trials, researches have elected to remove the bark and apply the paint directly on the xylem in order to have a smooth or flat surface for the application of speckling. This potentially limits the application of DIC systems only to destructive sampling. Percent strain on Quercus rubra L. stump sprouts was mapped, and no difference between the strains was found whether the bark was intact or removed, suggesting that the presence or absence of bark does not influence strain, at least in thin bark situations. As such, it is not always necessary to remove the bark, opening up the applicability of DIC systems to nondestructive testing in ecological and arboricultural research, inclusive of repeat testing over a series of months or years.
Statins for primary prevention of cardiovascular disease

Statins significantly reduce cardiovascular morbidity and mortality in patients with and without coronary heart disease. Recently, much debate has focused on use of statins for primary prevention following a class-wide safety label change by the US Food and Drug Administration amidst concerns of worsened hyperglycemia. Here, we review the evidence for statins in primary prevention and offer guidance for their appropriate use.Two meta-analyses published since 2012 unequivocally support statins for primary prevention. Data from the Cholesterol Treatment Trialists' Collaborators demonstrated a 9% [relative risk (RR) 0.91, 95% confidence interval (CI) 0.85-0.97] reduction in all-cause mortality and a 25% (RR 0.75, 95% CI 0.70-0.80) reduction in major vascular events per 1.0 mmol/l reduction in low-density lipoprotein cholesterol, even among low-risk patients. A 2013 Cochrane review corroborated these findings including a 14% (OR 0.86, 95% CI 0.79-0.94) reduction in all-cause mortality and a 25% (RR 0.75, 95% CI 0.70-0.81) reduction in cardiovascular disease events with statin therapy despite an 18% (RR 1.18, 95% CI 1.01-1.39) increase in incident diabetes.Statins effectively lower atherogenic lipoproteins and result in clinically significant reductions in cardiovascular morbidity and mortality. When well tolerated, the cardiovascular benefits of statins for primary prevention generally far outweigh the reported harms.
Destination SMEs

CONTEXT:
Policies aiming at supporting SMEs lack some effectiveness and efficiency in the tourism sector in many European regions. With a more favourable environment, SMEs could grow faster and create more jobs. For tourist SMEs, it would require the creation of a management strategy of the territory, i.e. a Destination Management strategy.

PARTNERSHIP:
The project brings together 7 partners from 7 EU countries (FR, IT, MT, IE, FI, LT, SI) consisting of a mix of public authorities at national, regional and local level and agencies having a delegation of competences from their public authority. When relevant, authorities in charge of targeted policies are committed to provide their entire support. Relevant stakeholders within each area will be strongly involved in the exchange of experience at interregional level and planned adaptation of policy instruments.

OBJECTIVE:
Improve public policies (through structural funds, national or regional policy instruments) dedicated  to the support of tourist SMEs and their competitiveness.

APPROACH:
Three-steps approach in Phase 1. Interregional exchange of experiences in that field and subsequent introduction into their policies of solutions for a better destination management of the territory (final purpose under Phase 2).

MAIN ACTIVITIES AND OUTPUTS:
7 policy instruments are addressed (1 per region), among which 5 relate to structural funds programmes. Basis for exchange of experience: Reciprocal improvement analysis and 7 study trips with peer-review of each partner’s practices. Video newsletters and a movie for an effective dissemination towards other territories in Europe.

MAIN EXPECTED RESULTS:
At least 14 good practices identified. 7 targeted policy instruments improved. At least 21 staff members will transfer new capacities in their intervention fields. At least 30 involved stakeholders with increased skills and knowledge from exchange of experience. Expected 15 appearances in press and media, including at European level.
Design of an STT-MTJ based true random number generator using digitally controlled probability-locked loop

This paper presents a design of a True Random Number Generator (TRNG) using a Spin Transfer Torque Magnetic Tunnel Junction (STT-MTJ) device. Since the probability of the STT-MTJ-based TRNG is locked using a digitally controlled feedback loop, the sensitivity of the feedback gain can be reduced greatly, which eliminates a high-gain amplifier in the feedback loop. It is demonstrated using the circuit simulator (NS-SPICE where the STT-MTJ model is established based on 90nm CMOS/MTJ process technologies) and MATLAB that the random sequences generated from the TRNG become 50%, where the gain of signal converters in the probability-locked loop is the precision of at most 9bit.
Improving the understanding of DNA–propanediyl-1,3-bis(dodecyldimethylammonium) dibromide interaction using thermodynamic, structural and kinetic approaches

A kinetic, thermodynamic and structural study of the interaction of the gemini surfactant propanediyl-1,3-bis(dimethyldodecylammonium dibromide) (12-3-12.2Br) with calf thymus DNA was carried out at several ionic strengths (NaCl) in aqueous solutions. A new 12-3-12(2+)-selective membrane was prepared in order to gain insight into the factors that control the binding of 12-3-12.2Br to DNA. We used ethidium bromide (EB) as a fluorescence probe to follow the kinetics of the interaction by using the stopped-flow fluorescence technique. The results can be explained in terms of a reaction mechanism involving two consecutive reversible (fast and slow) steps. The fast step was attributed to the union/separation of the surfactant with/from the DNA polynucleotide. Changes in the kinetic constants in the forward and backward directions were discussed in terms of the Brönsted-Pitzer equation and of the increase in hydrophobic interactions of the surfactant tails as a consequence of salting-out effects, respectively. The slow step corresponds to a conformational change of the surfactant-DNA complex to a more compacted form. The equilibrium constant, calculated from the forward and reverse rate constants of these steps, agrees with the results obtained from potentiometric titration using a 12-3-12-(2+) selective electrode.
Avant-Garde r&d platform and demonstration plant towards efficient industrial biotechnologies

Within the last years, the consumer’s trends have massively been turning away from artificial and petrochemical additives in favour of natural equivalents considered as healthier and eco-friendlier. In this context, facing traditional methods such as chemical synthesis (requiring toxic products and energy craving) or extraction from natural sources (usually at high cost, with high social/environmental toll), biocatalytic routes are intensively studied as alternative for the synthesis of molecules. Biocatalytic processes, that use natural catalysts such as enzymes or microorganisms, are considered as the most promising way to produce numerous chemicals. Nevertheless, due to several technical and financial intrinsic barriers, biocatalysis struggles to go out from laboratories and conquer the century-old chemical industry outside of the high added-value pharmaceuticals field. 

Since its creation in 2003, the spirit of NATURAMOLE, technology-driven biotechnology company, has been to address the need for eco-friendly products and processes by the formulation industry. Coupling a R&D platform and a demonstration plant, our project, called the Green Factory, aims at leveraging 15 years of successful R&D on enzymatic esterification and its industrialisation to broaden the scope of application of our novel biotechnologies towards new target markets with higher volumes and lower prices. Through our unique enzymatic technology, we propose to accelerate the industrial transition from polluting chemistry to a more sustainable model conciliating cost-efficiency and environmental performance. 

Today, NATURAMOLE presents a consolidated commercialisation roadmap to address the needs of the flavours and fragrances industries. With Green Factory, we expect to expand the scope of biocatalytic technologies to other markets, starting with natural cosmetics and ecological lubricants, and reach over a 6-year period a cumulated net income of € 31.7 million.
Real- and redshift-space halo clustering in <i>f</i> ( <i>R</i> ) cosmologies

We present two-point correlation function statistics of the mass and the halos in the chameleon $f(R)$ modified gravity scenario using a series of large volume N-body simulations. Three distinct variations of $f(R)$ are considered (F4, F5 and F6) and compared to a fiducial $\Lambda$CDM model in the redshift range $z \in [0,1]$. We find that the matter clustering is indistinguishable for all models except for F4, which shows a significantly steeper slope. The ratio of the redshift- to real-space correlation function at scales $> 20 h^{-1} \mathrm{Mpc}$ agrees with the linear General Relativity (GR) Kaiser formula for the viable $f(R)$ models considered. We consider three halo populations characterized by spatial abundances comparable to that of luminous red galaxies (LRGs) and galaxy clusters. The redshift-space halo correlation functions of F4 and F5 deviate significantly from $\Lambda$CDM at intermediate and high redshift, as the $f(R)$ halo bias is smaller or equal to that of the $\Lambda$CDM case. Finally we introduce a new model independent clustering statistic to distinguish $f(R)$ from GR: the relative halo clustering ratio -- $\mathcal{R}$. The sampling required to adequately reduce the scatter in $\mathcal{R}$ will be available with the advent of the next generation galaxy redshift surveys. This will foster a prospective avenue to obtain largely model-independent cosmological constraints on this class of modified gravity models.
Análisis de las implicaciones financieras de la reforma eléctrica en una instalación tipo de energía renovable

The Royal Decree 413/2014 establishes the new remuneration system for generators of electricity from renewable energy sources, cogeneration and waste, based on the concept of reasonable profitability. In this paper, after explaining the background that led the Government to undertake this reform, it is analyzed at first the skeleton of the new salary basis. Then in a second stage the economic and financial implications of the reform for a particular installation fictitious, framed in a particular installation type category, are studied. This requires a feasibility analysis. The method can be extrapolated to any other type of project. The analyzed installation is a mini hydropower plant of 10 MW capacity, which gets the final operating license in 2007, with the installation type assigned to the IT-00708. 35% of the project is funded by the contributions of the partners and the other 65% by a long-term loan, articulated through a project finance. This analysis will include the 25 year life of the plant. In the first scenario analyzed the remuneration over the 25 years of analysis comes from the feed-in tariffs. In the second scenario, feed-in tariffs changes by mid-2013, passing to the specific fee system established in the reform studied.
An ANP-based assessment model for lean enterprise transformation

There is a multitude of methodology on evaluation of lean transformation, but only few consider the relationships among the components of the lean enterprise transformation explicitly and focus on their prioritization and identification of the relative importance weights for every element of the lean transformation. For that reason, we try to quantify those relationships in this study. For a structured examination of the relationships among the elements, we suggest a model that provides a holistic view to the lean transformation process. This paper presents an analytic lean enterprise transformation modeling approach to the identification of weights of the organization’s lean transformation determinants. Thus, the highly qualitative relationships among the lean transformation components are operationalized. For determining of the relative importance weights for every element in the model, analytic network process modeling approach is used in the proposed framework. This approach has enabled us to apply the proposed lean enterprise transformation methodology at a global industrial manufacturing company in Turkey, and an illustrative case is presented.
Evolution and impact of heterochromatin on a young drosophila y chromosome

The transition from euchromatin to heterochromatin is a fundamental process that particularly reshaped the epigenomic landscape of Y chromosome. Its definitive genomic underpinning and broad functional impact are still unclear, as heterochromatin (e.g., that of human Y) is usually too repetitive to study. I have previously demonstrated that, the young Y (‘neo-Y’) chromosome of Drosophila miranda has just initiated such a transition, thus is a powerful model to unveil the evolution, regulation and functional interaction of heterochromatin. I showed that this neo-Y still harbours over 1800 genes, and only 20-50% of the sequences are transposable elements (TE). Over five years, I aim to: 1) precisely resolve the structure and insertion sites of TEs as a pre-requisite for studying heterochromatin, by combining state-of-art sequencing and bioinformatic techniques. 2) I will reveal the de novo heterochromatin formation triggered by TE insertions or the heterochromatin/euchromatin boundary shifts on the neo-Y, by comparing the binding profiles of histone modification hallmarks and insulator proteins of D. miranda to its sibling species D. pseudoobscura, which lacks the neo-Y. Such epigenomic changes have likely driven the exaptation or innovation of small RNA pathways that govern the TE mobility. 3) I will then identify the responsible small RNAs and their encoding loci, which are expected to have newly emerged or differentially expressed in D. miranda relative to D. pseudoobscura. 4) Finally, I will develop CRISPR/Cas9 in D. miranda to manipulate the expression of TEs encoding such small RNAs on the neo-Y, in order to scrutinize how TE/heterochromatin evolution on the Y would impact the chromatin landscape of the entire host genome. The combined aim of this multidisciplinary project is to generate a framework for understanding the basic mechanisms of how heterochromatin evolves; and open a new avenue toward the discovery of Y chromosome function beyond male determination.
GRANULES CONTAINING ONE OR MORE HIGHLY ACTIVE SUBSTANCES AND METHOD FOR PRODUCING THE SAME

The invention relates to storage-stable granules that contain one or more highly active substances and that have no tendency to bleed or agglutinate even at high active substance contents (> 20 wt.- % based on the granules). Said granules contain one or more active substance(s) and substrate(s), the substrates being at least partially selected from substances that are capable of forming inclusion compounds. Dry pulverization of said materials as well as other materials is suitable to produce highly absorptive and adsorptive carrier materials.
The magnetic field and circumstellar environment of the helium-strong star HD 36485 =δ Ori C

Extensive Hα spectroscopy of the cool, helium-strong star δ Ori C obtained over two decades has enabled a detailed analysis of the variable Hα emission observed in this sharp-lined and strongly magnetic B3V star. Radial velocity measurements from these and other spectra have also confirmed the binary nature of the star, the first detection of the secondary being provided, and permitted an improved determination of the system’s orbital parameters. The amplitude of the radial velocities and a preliminary spectroscopic analysis indicate that the secondary component is an early A-type star. Disentangling the contribution of the two components to the Balmer line profiles, we determine an effective temperature for δ Ori C slightly larger than previously adopted in the literature. The Hα emission is variable with a period of 1.477 75 ± 0.000 04 d, assumed to be the rotation period of the primary component. After removal of the binary system’s photospheric contribution to the Hα line, we find that the emission arises from two distinct, but asymmetrical, optically translucent circumstellar clouds. When strongest the emission peaks have intensities of approximately 15 per cent of the continuum level at about 150 km s −1 on either side of the line centre, and emission is apparent to ±225 km s −1 ,o r 6R∗ above the photosphere if we assume that the magnetic field forces the circumstellar material into rigid rotation about the star. New 6 cm Very Large Array radio measurements, when combined with archival data, suggest that the radio flux of the star is also variable. An analysis of new and previously published magnetic field observations enabled us to derive a value for the inclination of the rotation axis of i = 12 ◦ ± 3 ◦ and an obliquity of the magnetic axis of β ≤ 52 ◦ . The nature of the emission variability is similar to that of the prototypical helium-strong star σ Ori E, but since the latter object has an inclination of >75 ◦ , δ Ori C provides us with an opportunity to investigate the cool components of the winds and magnetospheres of the helium-strong stars from a different vantage point.
Projet GIPRO 10+

Avec l’expansion de l’usine et l’utilisation de nouvelles technologies dans le domaine de la transformation de la résine coulée, il est prévu d’innover et de développer de nouveaux marchés.
Haptoglobin Genotype-Dependent Anti-Inflammatory Signaling in CD163+Macrophages

Intraplaque hemorrhage causes adaptive remodelling of macrophages towards a protective phenotype specialized towards handling iron and lipid overload, denoted Mhem. The Mhem phenotype expresses elevated levels of hemoglobin (Hb) scavenger receptor, CD163, capable of endocytosing pro-oxidant free Hb complexed to acute phase protein haptoglobin (Hp). It is notable that individuals homozygous for the Hp 2 allele (a poorer antioxidant) are at increased risk of cardiovascular disease compared to the Hp 1 allele. In this study, we examined whether scavenging of polymorphic Hp:Hb complexes differentially generated downstream anti-inflammatory signals in cultured human macrophages culminating in interleukin (IL)-10 secretion. We describe an anti-inflammatory signalling pathway involving phosphatidylinositol-3-kinase activation upstream of Akt phosphorylation (pSer473Akt) and IL-10 secretion. The pathway is mediated specifically through CD163 and is blocked by anti-CD163 antibody or phagocytosis inhibitor. However, levels of pSer473Akt and IL-10 were significantly diminished when scavenging polymorphic Hp2-2:Hb complexes compared to Hp1-1:Hb complexes<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M1"><mml:mrow><mml:mo stretchy="false">(</mml:mo><mml:mrow><mml:mi>P</mml:mi><mml:mo>&lt;</mml:mo><mml:mn>0.05</mml:mn></mml:mrow><mml:mo stretchy="false">)</mml:mo></mml:mrow></mml:math>. Impaired anti-inflammatory macrophage signaling through a CD163/pAkt/IL-10 axis may thus represent a possible Hp2-2 disease mechanism in atherosclerosis.
Local Governments Network of Central and Eastern European Countries

The operation “CEEC-LOGON” is a platform for strategic cooperation between Associations of Local and Regional Authorities in the Accession Countries of the European Union and Member States of the EU. The network was founded in 1998 by the Austrian Association of Cities and Towns together with the Council of European Municipalities and Regions (CEMR). The network includes 24 city and municipality organisations from 19 different countries, 7 of which are partners from old Member States, 15 from new Member States and 2 from Accession Countries. LOGON focuses on transferring experiences of local governments in EU Member States on how to build capacity for effectively dealing with EU policies and the challenges and opportunities of EU membership. Overall objective / Objectif général The overall objective of the operation is to deepen the LOGON network through focusing on practical issues of urban management. The systematic exchange of experience and know-how transfer should stimulate the development of more efficient and effective policies, instruments and methods in the context of Structural Fund management and in relation to other relevant EU programmes. Issues to be dealt with are human resources development, services of general interest, EU structural and regional policy for cities, public management for cities and good governance. Expected results / Résultats attendus The operation will help to strengthen the capacity of cities and their associations to manage urban projects and related EU funding. It should also help them to more effectively represent their interests at national and EU-level. Conferences involving politicians, experts and representatives of local authorities on the abovementioned issue areas will be documented in reports and a guidebook to be translated and disseminated to all partner countries. The LOGON info point (Internet site) will be expanded and improved to maximise the spread of knowledge among partners and to offer a sophisticated information source
Military emergency tourniquet

The military emergency tourniquet is a device for rapidly and easily reducing or stopping blood flow to a limb. The tourniquet utilizes a closed loop system and includes a twistable strap, a base including two opposing entry apertures and an exit aperture, a windlass and at least one receiving loop. The twistable strap is slidably positioned through the opposing entry apertures and the exit aperture thereby forming a closed loop. The windlass is positioned outside of the closed loop and is affixed to one end of the strap. The windlass includes an aperture capable of sliding the opposing end of the strap therethrough. The receiving loop receives an end of the windlass and is affixed to the base.