SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Support INsular and low density areas in the transition towards a more CIRCuLar tourism Economy

Natural resources in vulnerable MED tourist territories, such as islands and scarcely inhabited areas, are at stake. The carrying capacity of such MED destinations is often counterposing interests of tourist stakeholders and local communities. A joint response and a shared methodological framework to policy making are required in tackled territories, to seize the sustainability challenge, especially in terms of an improved and integrated sustainable tourism planning to preserve and valorise non-renewable resources.INCIRCLE will build up on previous projects, capitalising knowledge and available tools to test a new methodology that will apply the principles of circular economy to the tourism sector, with a focus on the peculiar needs of islands and low density areas. 

INCIRCLE tailored policies will address mobility, energy efficiency, use of limited resources as water and waste production, while enhancing community prosperity and quality of life.Durable and easily adaptable outputs are envisaged to provide MED decision makers with concrete tools and testing opportunities to improve their capacity in terms of assessing and planning sustainability in territories where resources are already scarce, to disclose new funding and concrete replication opportunities, establishing a critical mass for a MED sustainable and circular growth. Capitalization activities will replicate activities in further territories and mainstream results in regional, national and European policies.
LIGHT-EMITTING DIODE MATRIX AND METHOD FOR MAKING SAME

The invention concerns a light-emitting diode matrix device for obtaining high light intensity as well as peak luminance, and the method for making same. Thus, said array comprises light-emitting diodes (2) incorporated in packaging housings (1) made of moulded resin whereof the planar upper surface (5), forming an optical output window (6), receives a bonded hemispherical glass or plastic lens (11), with identical or substantially identical index to that of the resin, such that said window (6) is located at a specific distance from the emitting surface of the semiconductor component (2) so that said emitting surface is proximate to the object Weierstrass point of the spherical diopter thus formed by said hemispherical lens (11). More particularly, the light-emitting diode housings (1) are soldered by surface-mounted component process, on an electronically powered support card (9) and the free space between said housings (1) is coated with a jointing paste.
Technology for self removal of spacecraft

Orbital space is getting increasingly crowded and a few collision events could jeopardize activities in important orbits and
cause significant damage to the infrastructure in space. As a preventive measure to be included in future S/C, TeSeR
proposes a universal post mission disposal module to be carried into orbit by any S/C to ensure its proper disposal after
ending its service lifetime, be it planned or unscheduled due to S/C failure. This module shall be independent of the S/C.
Principal aims of TeSeR are to
1. develop a removal module beginning with the exploration of concepts, going for a functional design with the aim to
manufacture and test an on-ground prototype module which demonstrates the main functions
2. perform a thorough qualitative and quantitative mission analysis of existing removal concepts
3. develop a ground breaking new semi-controlled removal concept based on a passive removal concept which ensures the
deorbit of a large S/C (>1 t) into the Pacific Ocean without a propulsion system but with an accuracy of a fraction of one orbit
4. advance and manufacture removal subsystems prototypes, for controlled, semi-controlled and uncontrolled disposal,
based on already existing technology with the focus on scalability and standardized implementation to the removal module via a common interface
5. analyse the feasibility and potential advantages of multi-purpose concepts of the module and its removal subsystems (e.g.
shielding by deployable structures)
6. perform a market study and define a business case for TeSeR
7. use TeSeR as leverage to propose changes in legal aspects and advanced state of the art licensing standard for
spacecraft including the improvement of international debris mitigation guidelines and standards
Molecular simulation of interfacial mechanics for solvent exfoliation of graphene from graphite

The interfacial force for exfoliating a graphene monolayer from graphite in solvent media was studied by restrained molecular dynamics simulations. Three solvents, N-methylpyrrolidone (NMP), dimethyl sulfoxide (DMSO), and water, were considered. The interfacial structures show that NMP and DMSO have a stronger affinity with graphene surfaces. In the solvent media, there exists an inherent attractive force hindering the exfoliation, which is almost exclusively determined by the interaction between graphene sheets. Along the perpendicular exfoliation direction (relative to the graphene plane), the initial exfoliation is less dependent upon solvent conditions, and the subsequent exfoliation can be facilitated by the solvent-induced interaction. However, along the shift direction parallel to the graphene plane, the organic solvent provides a favorable driving force to assist the exfoliation, whereas water offers obstructing effect. The parallel shift of graphene requires less external power than the perpendicular shift for our simulated systems. The confined solvent molecules between graphene sheets play an important role in exfoliating and stabilizing graphene in solvent media. This result provides a microscopic understanding of the function of solvent-induced interaction in the solvent exfoliation of graphene.
Aberrant methylation of genes in stool samples as diagnostic biomarkers for colorectal cancer or adenomas: A meta-analysis

An increasing number of hypermethylated genes in stool samples have been reported as biomarkers for the detection of colorectal cancer (CRC) or adenomas. We aimed to comprehensively review and compare the evidence for feasibility of using these biomarkers for the detection of colorectal neoplasia.We searched Medline, the Web of Science and OVID for studies that used hypermethylated genes as biomarkers for the detection of CRC or adenomas. A meta-analysis was carried out using the random-effect model with diagnostic odd ratios (DOR) and 95% confidence intervals (CI) as effect measurements.A total of 19 studies including 2,356 patients were eligible for final analysis. The sensitivity, specificity, positive likelihood ratio, negative likelihood ratio and DOR for the detection of CRC or adenomas were 0.62 (95% CI: 0.51-0.71), 0.89 (95% CI: 0.86-0.92), 5.66 (95% CI: 4.68-6.83), 0.43 (95% CI: 0.34-0.55) and 13.15 (95% CI: 9.82-17.60) respectively. Of these, the sensitivity and specificity for the detection of adenoma were 0.54 (95% CI: 0.39-0.68) and 0.88 (95% CI: 0.83-0.92) respectively.Hypermethylated gene panels are not currently accurate enough to be used alone for colorectal neoplasia screening. The discovery and evaluation of additional biomarkers with improved sensitivity and specificity is necessary.
A portable single-molecule fluorescence imager

This proposal focuses on activities that support the advancement of a novel compact optical microscope to the proof-of-concept stage. The microscope (“NanoImager”) is based on single-molecule fluorescence imaging; its development resulted from efforts to improve microscopes within the ERC project POLMACHINE. 

Single-molecule fluorescence is the most popular way of visualizing single molecules, especially in living cells; imaging-based microscopes are the most popular of fluorescence microscopes. However, there are few commercial single-molecule fluorescence microscopes; the existing ones are large, complex and expensive. In contrast, the NanoImager has the potential to be can be much smaller and affordable, while matching the high sensitivity, high temporal/spatial resolution, and stability of the larger microscopes.  As such, the NanoImager can address large unmet needs in research, teaching, ultrasensitive analysis, and biomedical diagnostics, and open new applications, especially due to its robustness, portability, size and cost. 

To bring the Nanoimager closer to the market, we will develop an advanced prototype and explore opportunities for its commercialization. Specifically, we will build and test a prototype fully equipped with software for instrument control and data analysis; we will also work with early adopters to test the prototype and prepare it for the broader market. Finally, we will also perform business-related activities to explore routes for commercialization (from licencing to a spin-out) and clarify the IP landscape. The final outcomes of the project will be the improvement of our prototype up to commercial standards, a clear definition of the competitive and novel aspects of our technology, and an informed, leveraged decision regarding its route to the market.
Detection of genes by amplification with primers specific for CpG islands and that incorporate restriction enzyme recognition sequences

A method for detection of genes comprises amplification of DNA with one or more primers chosen from 20 that were designed based on the 5' CpG islands of genes and hybridization of the amplified DNA with a DNA library. A method for detection of genes comprises the following steps: amplification of a DNA with one or more of the following primers: GCGCGCNN; GCGGCCGC; CCGCGGNN; CGCGNNNN; GGCGCGCC; GGGCCCNN; CGATCGNN; CGGWCCGN; CGGCCGNN; GGCCGGCC; ACGCGTNN; GCCGGCNN; GGCGCCNN; CCNNGGNN; TCGCGANN; CGGNCCGN GTCGACNN; GGCCNNGGCC; CGCCGGCG; or GCCCGGGC; and hybridization of the amplified DNA with a DNA library. N = G or C; W = A or T
Multi-objective optimization approach toward conceptual design of gas turbine combustor

Abstract This paper focused on the conceptual design of a conventional gas turbine combustor via the multi-objective optimization approach. The suggested method integrated the design and estimation of the performance of the combustion chamber. The geometry and performance parameters could be found by applying the design tool. According to the level of available information in the primary phases of the design process, a chemical reactor network approach for modeling the combustion was chosen; thus, the droplet evaporation of the liquid fuel and unmixedness of the fuel-air mixture in the primary zone was modeled. The results obtained from the design tool for the two annular combustors were compared with the empirical data and showed an acceptable convergence between the dimensions and exhaust pollutants emission. The targets in the optimization process were the amount of the emission indices for two important pollutants (NOx and CO) produced by engines. Also, the parameters of the mass fractions of the primary zone, secondary zone, dilution zone, and the length of the primary and secondary zone were considered as the optimization variables. The results of the optimization process showed that minor changes in the combustor design could minimize the specified objectives to an acceptable level.
A Novel Bat Algorithm Based Re-tuning of PI Controller of Coal Gasifier for Optimum Response

AbstractIn this paper a novel BAT algorithm, a recently developed metahuristic algorithm is used to retune the parameters of pressure loop PI controller of coal gasifier, which is a highly nonlinear multivariable process having five controllable inputs and four outputs and strong interactions among the control loops. Functioning of coal gasifier involves many constraints to be satisfied on inputs and outputs. The existing controller along with its tuned parameters does not able to satisfy the constraints at 0% load for sinusoidal pressure disturbance and provides better response at 100% and 50% load conditions. The parameter of pressure loop PI controller is re-tuned using Lévy Flight (LF) guided BAT algorithm and performance tests which includes, pressure disturbance test, load change test and coal quality test are conducted. Test results shows that the re-tuned controller provides better response, meeting all the constraints at 0%, 50% and 100% load conditions.KeywordsBat AlgorithmALSTOM benchmark challenge IICoal gasifierIntegrated Gasification Combined CycleMetahuristic AlgorithmLévy Flight
Advances in ZnO–Bi2O3 based varistors

In this review paper detailed development of the ZnO–Bi2O3 based polycrystalline varistors are presented as the technological importance emerged with the rapid applications of the gapless surge protectors superseding traditional gapped SiC designs. The excellent symmetric nonlinear current–voltage (I–V) characteristic of these varistors results from the type of back-to-back electrical potential barriers that are formed between the successive ZnO grains during the step-wise processing cycles. The role of microstructures and the defect structures in conjunction with the processing parameters paved the road to the understanding of the degradation and failure mechanisms of the electrical potential barriers for acceptable protective characteristics. The nature of the processing variables influencing eventual performance of varistors is discussed.
MULTISTEP ISOLATION OF WELL AND HYDRAULIC FRACTURING

FIELD: instrument making.SUBSTANCE: according to one aspect of proposed invention, disclosed is a valve for hydraulic fracturing, comprising one or more ports, a coupling capable of occupying a closed position whereat it prevents fluid flow through said one or more ports, and an open position whereat it ensures possibility of fluid flow through said one or more ports. Coupling is configured to change from closed position to open and valve seat, receiving ball and detachably connected with said coupling. Transition of coupling from closed position to open is caused by ball falling into said valve seat. According to another aspect of implementation of present invention, disclosed is a valve for hydraulic fracturing, which comprises a valve seat to receive ball, which is detachably installed inside valve tool. Said valve seat has an accommodating profile providing reception of ball. Said accommodating profile along radius of curvature is matched with ball to ensure non-deforming cover of ball.EFFECT: higher efficiency of valve tool.19 cl, 6 dwg
Support Patients through E-services Solutions

The topic of telemedicine offers potential for greater social cohesion in Europe as well as numerous advantages and has already begun to fill a major role in, and to change, the manner in which people interact with healthcare. Transnational cooperation in the respective field may lead to innovative and shared solutions in order to fulfil the goal to move towards a "European eHealth Area", recognised by the European Commission.

The role of local authorities in the area of healthcare is to develop a reliable system able to check, record and compare the medical conditions within the particular region. The telemedicine can be solution for many regions having impact also on reduction of traffic and positive effects on the environment.

SPES project focuses on the practical implementation of technical tools already developed designed to ease the life of older people in their homes focusing on respiratory problems, dementia, handicapped people and socially excluded population.
Restricting range restricts conclusions

THE EXPERTISE APPROACH AND SKILL ACQUISITION Research on expertise is by definition focused on a restricted sample of individuals. Experts are people who consistently produce outstanding performance in their domains (Ericsson, 2006) and as such are without exception located on the positive side of the skill distribution. The usual approach in the study of expertise is to compare the extreme group of the skill distribution, experts, with the extreme group at the other end, that of novices. This contrasting approach, which we have called the “expertise approach” (Bilalic et al., 2010, 2012), has a long tradition (Chase and Simon, 1973; Simon and Chase, 1973; De Groot, 1978; Preacher et al., 2005). Its main advantage over the common approach in cognition, where all participants are at the same skill level, is the presence of a control group of novices that enables falsification of results obtained on experts (Wason, 1960; Kuhn, 1970; Campitelli and Speelman, 2013). In that way, the expertise approach is not unlike the neuropsychological approach that contrasts results obtained on patients with the results of “normal” participants (Shallice, 1988). The main goal of the expertise approach is to provide evidence relating to the cognitive and neural mechanisms behind processes such as object and pattern recognition, which would be difficult to obtain from subjects who possess approximately the same level of expertise. The skill acquisition process, which is one of the main topics of expertise (William and Harter, 1899), is of secondary importance in the expertise approach. This is understandable as the contrast between experts and novices captures only the beginning and the end product of the skill acquisition process. It is unrealistic to follow people for the length of time required in order to achieve expertise in a given domain. However, expertise researchers have recently started employing an archival approach that provides a more complete picture of the skill acquisition process (Charness and Gerchak, 1996; Chabris and Glickman, 2006; Howard, 2008, 2009; Bilalic et al., 2009). In the game of chess, a domain commonly studied in expertise research, there are precise records of all practitioners from an early age (Howard, 2006a; Bilalic et al., 2009). These records include not only personal information such as gender and age, but also skill levels at different stages, numbers of games played, and corresponding skill change. The records provide a wealth of data for investigating the influence of factors such as age, gender, and even talent, on the skill acquisition process. Here we want to draw attention to the fact that some of the databases used in previous research only provide records of the very best practitioners. In the expertise approach, such restriction is an integral part of the methodology, but restricting the range of population in the archival approach could have grave consequences for the conclusions about the nature of skill acquisition.
Archaeometric case-study of tiles of different dates from the Royal Monastery of San Lorenzo de El Escorial (Spain)

With the aim to contrast existing historical documentation with information provided by the own materials, an archeometric study of a representative set of tiles from the Monastery of El Escorial was undertaken. The ensemble, composed of 19 ceramic fragments, covers examples from the 16th and 17th century, either from Talavera or Toledo provenances, and was selected according to stylistic criteria. The goals of the study consisted in determining the average chemical composition of the ceramic body, its textural and microstructural characteristics, the crystalline phases to establish firing temperatures, also in studying these aspects in the enamel or glaze layer, as well as in identifying the chromophores for the coloring of the decorations. Conventional techniques such as binocular magnifying glass, XRF spectrometry, petrographic observation by thin-section, XRD, FESEM with EDS microanalysis and visible spectrophotometry were used. Resulting data indicated the use of calcareous clays for the body (22.0–25.5 wt.% CaO), the presence of neoformed phases such as gehlenite, diopside and anortite which suggest a firing temperature between 950 and 1050 °C approximately, lead-based glazes (∼25.0 wt.% PbO on average) with SnO2-opacifier (∼57.0 wt.% on average) and Co2+, Cu2+, Fe3+-ions and lead antimoniate for blue, green, brown and yellow decorative colors, respectively. Con el objetivo de contrastar la documentación histórica existente con la información proporcionada por los propios materiales se realizó un estudio arqueométrico de un conjunto representativo de azulejos procedentes del Monasterio de El Escorial. El conjunto, compuesto por 19 fragmentos cerámicos, cubre ejemplares de los siglos xvi y xvii, tanto de posible procedencia talaverana como toledana, y se seleccionó según criterios estilísticos. Los objetivos del estudio consistieron en determinar la composición química promedio del cuerpo cerámico, sus características texturales y microestructurales, las fases cristalinas para establecer las temperaturas de cocción, también en estudiar estos aspectos en la capa de esmalte o vidriado, así como en identificar los cromóforos de la coloración de las decoraciones. Se utilizaron técnicas convencionales como lupa binocular, espectrometría de FRX, observación petrográfica mediante lámina delgada, DRX, MEBEC con microanálisis EDS y espectrofotometría visible. Los datos resultantes indicaron el uso de arcillas calcáreas para el cuerpo cerámico (22,0-25,5% en peso de CaO), la presencia de fases neoformadas como gehlenita, diópsido y anortita que sugieren una temperatura de cocción de entre 950 y 1.050 °C, aproximadamente, esmaltes de base plomo (promedio ∼25,0% en peso de PbO) con SnO2 (promedio ∼57,0% en peso) como opacificante y presencia de iones Co2+, Cu2+, Fe3+ y antimonio de plomo para los colores azul, verde, marrón y amarillo, respectivamente, de las decoraciones.
Influence-Based decision-making in uncertain environments

Decision-theoretic sequential decision making (SDM) is concerned with endowing an intelligent agent with the capability to choose actions that optimize task performance. SDM techniques have the potential to revolutionize many aspects of society and recent successes, e.g., agents that play Atari games and beat a world champion in the game of Go, have sparked renewed interest in this field.

However, despite these successes, fundamental problems of scalability prevents these methods from addressing other problems with hundreds or thousands of state variables. For instance, there is no principled way of computing an optimal or near-optimal traffic light control plan for an intersection that takes into account the current state of traffic in an entire city. I will develop one in this project.

To achieve this, I will develop a new class of influence-based SDM methods that overcome scalability issues for such problems by using novel ways of abstraction. Considered from a decentralized system perspective, the intersection’s local problem is manageable, but the influence that the rest of the network exerts on it is complex. The key idea is that by using (deep) machine learning methods, we can learn sufficiently accurate representations of such influence to facilitate near-optimal decisions.

This project will construct a theoretical framework for such approximate influence representations and SDM methods that use them. Scalability of these methods will be demonstrated by rigorous empirical evaluation on two simulated challenge domains: traffic lights control in an entire city, and robotic order picking in a large-scale autonomous warehouse.

If successful, INFLUENCE will produce a range of influence-based SDM algorithms that can, in a principled manner, deal with a broad range of very large complex problems consisting of hundreds or thousands of variables, thus making an important step towards realizing the promise of autonomous agent technology.