SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Encapsulation of adipose-derived stem cells and transforming growth factor-β1 in carrageenan-based hydrogels for cartilage tissue engineering

Tissue engineering (TE) is an emerging field for the regeneration of damaged tissues. The combination of hydrogels with stem cells and growth factors (GFs) has become a promising approach to promote cartilage regeneration. In this study, carrageenan-based hydrogels were used to encapsulate both cells and transforming growth factor-β1 (TGF-β1). The ATDC5 cell line was encapsulated to determine the cytotoxicity and the influence of polymer concentration on cell viability and proliferation. Human adipose-derived stem cells (hASCs) were encapsulated with TGF-β1 in the hydrogel networks to enhance the chondrogenic differentiation of hASCs. Specific cartilage extracellular matrix molecules expression by hASCs were observed after 14 days of cultures of the constructs under different conditions. The κ-carrageenan was found to be a suitable biomaterial for cell and GF encapsulation. The incorporation of TGF-β1 within the carrageenan-based hydrogel enhanced the cartilage differentiation of hASCs. These findings indicate that this new system for cartilage TE is very promising for injectable thermoresponsive formulation applications.
Bivariate geostatistical modelling: a review and an application to spatial variation in radon concentrations

We present a comprehensive review of multivariate geostatistical models, focusing on the bivariate case. We compare in detail three approaches, the linear model of coregionalisation, the common component model and the kernel convolution approach, and discuss similarities between them. We demonstrate the merits of the common component class of models as a flexible means for modelling bivariate geostatistical data of the type that frequently arises in environmental applications. In particular, we show how kernel convolution can be used to approximate the common component model, and demonstrate the method using a data-set of calcium and magnesium concentrations in soil samples. We then apply the model to a study of domestic radon concentrations in the city of Winnipeg, Canada, in which exposure was measured at two sites (bedroom and basement) in each residential location. Our analysis demonstrates that in this study the correlation between the two sites within each house dominates the short-range spatial correlation typical of the distribution of radon.
Majorana bound states in ge/sige heterostructures

Each particle has its antiparticle, and upon bringing them in close vicinity, they annihilate (they disappear). A fundamental question arises: what happens if a particle is its own antiparticle? Ettore Majorana predicted their existence and evidence has been put forward for the existence of such a state of matter in the form of quasiparticle excitations in hybrid semiconductor-superconductor devices. Research activites so far has concentrated on InAs nanowires, planar InAs and InSb nanowires. Theory suggests to look for Majorana bound states (MBS) in Germanium and I propose to use a novel yet promising material system, namely a Germanium/Silicon-Germanium heterostructure, to provide evidence for the topological state of matter leading to Majorana bound states (MBS). Using Ge/SiGe brings the advantage of a long mean free path, which will allow for a larger spatial separation of the MBS and facilitate the long anticipated but yet elusive detection of correlation of two MBS. Additionally, the planar geometry brings the possibility to couple the MBS to their environment, which will be important for their usage as topologically protected quantum bits for quantum computation. I propose to show step-by-step the ingredients necessary for a topological phase transition resulting in MBS. In particular, I will follow these steps: I will collaborate with G. Isella's group to develop a highly mobile two-dimensional hole gas and make it accessible for magneto-transport measurements. I will further confine the holes into a one-dimensional wire with tunable tunneling barriers at each end. I will test the presence of a strong spin-orbit interaction by measuring helical transport. I will induce superconducting order by coupling the wire to NbTiN contacts. Finally, I will test the presence of MBS with tunneling conductance measurements and use a proper geometry to show evidence of the correlation of two MBS at each end of the wire.
EMBROIDERY SYSTEM

An embroidery system includes a data reading device to read three-dimensional data of a design of an embroidery. The embroidery system includes processing circuitry to process the three-dimensional data read by the data reading device, to create embroidery data using height information included in the three-dimensional data. The embroidery system includes an embroidery forming section to form the embroidery on a target object according to the embroidery data created by the processing circuitry. The embroidery system includes a recording head to discharge a liquid droplet from a nozzle. The embroidery system includes control circuitry to control an operation of the recording head. The embroidery data includes data relating to an embroidery density that is a density of a thread in the embroidery and data relating to an application amount of the liquid droplet to be applied to the thread in the embroidery.
FAKTOR-FAKTOR YANGMEMPENGARUHIKEBERHASILAN USAHAPEMEGANG USAHA WARALABA(Studi Kasus Pada Waralaba Makanan danMinumanLokal di Kota Semarang)

Business franchise (franchise) is now growing in Indonesia. This is because
in Indonesia with a population of over 200 million people who have the biggest
market opportunity. One type of franchise that is being developed at this time is the
category of food and beverage franchise locally. This study aims to determine the
influeace of to determine the influence of business characteristic, business location,
and management ability about success business franchising in Semarang. And to
analysis the dominant factor in a successful business franchising in Semarang.
The populations used in this study iis the holder of franchise business in
Semarang. Samples taken are as many as 82 respondents, by using Non-Probability
Sampling method and Accidential Sampling approaches, that is the sample
determination method based on coincidence, which are the holders of franchise
business in Semarang.
According to the stastictical data analysis, the outcome is that the indicators
used in this study are valid and the variables are reliable. The classical assumption
test, that is multicolinnearity regression model, indicate that there is no
hsteroscedasticity, and the distribution is normal. Furtheemore, the analysis result
proves the three variable in this study business characteristic variable indicated the
most dominant result in business success influence . with regression coefficient of
0,362 followed by business location variable with a regression coefficient of o,336.
and bussines characteristic with a regression coefficient 0,296. Those result indicate
that all of the independenrt varable affect positively and significancely toward the
business through the F-test and T-test, while the Adjusted R-square value of 0,524
indicate that 52,4% of franchise business variable. In Semarang could be explained
by yhose three independent variables, and the remaining 47,6% is explained by the
other factors outside the study
PHANTOM TO DETERMINE POSITIONAL AND ANGULAR NAVIGATION SYSTEM ERROR

A phantom to determine navigational error in a surgical navigation system that tracks the location of an elongate tool having a tip and a shaft based on a plurality of fiducials attached to the elongate tool. The phantom includes a base portion that models a lower portion of a mammalian head and having a top surface with a plurality of touch points, each of the touch points being a respective indentation, and a frame detachably securable to the base portion and having an upper portion spaced apart from the top surface, the upper portion having defined therein a plurality of apertures. A tip of the elongate tool is to be inserted through said one of the apertures and in one of the touch points, and the surgical navigation system determines positional and angular error.
ADVANCED METHODS, SYSTEMS AND DEVICES FOR REGISTERING INFORMATION IN A DATABASE

A method and system are provided for registering, in a database, a transaction between two parties, and for allowing a third party to cause an action to be performed in relation to the transaction. The method comprise a step of creating (s2) a transaction record, steps of electronically signing (s4, s12, s18, s26) the transaction record, steps of registering (s6, s14, s20, s28) the transaction record in the database, steps of issuing a notification (s8, s16, s22) that the transaction record has been registered in the database, steps of verifying (s10, s24) the transaction record by the third party, and a step of causing (s30), by the third party, an action to be performed based on transaction content information.
MRData: A MapReduce-Based Tool for Heterogeneous Data Integration

As the volume of data increasing sharply and the relationship among different data sources becoming intricately, how to integrate mass data sources and how to find latent information from the integrated data is a matter of urgency. At present, industry tends to adopt distributed computing model to solve the integration of massive data. Aiming at getting the valuable and in-depth information, visualization is a critical step in data analysis and data mining. We design a tool called MRData for heterogeneous data integration which has two features: 1) parallel data processing based on Hadoop which is a distributed platform; 2) visual analysis. And at last, experiments verify the efficiency of MRData.
Resurrecting the carboxyl polyether ionophores

The carboxyl polyether ionophores (CPIs) is a class of >150 complex natural products. Belonging to the most complicated of Nature's secondary metabolites, they are darlings within total chemical synthesis, however, the biological role of these agents is obscure. Due to their canonical function of equilibrating ion-gradients across biological membranes, CPIs are thought to be unspecific and largely uninteresting. Here, I will advocate and demonstrate the opposite position: that not only are these compounds extremely interesting with respect to their complex effects on cells, they also harbor a unique anti-microbial activity that should be a strong priority as we stagger towards a post-antibiotic era.    With RECYPION my team and I will draw these compounds back into the spotlight. We will ask the following fundamental questions: 1. Can we develop a synthesis-paradigm that will significantly expand the CPI-chemical space to fully explore their anti-microbial activities? 2. What are the molecular determinants that control the antibiotic-potential of the CPIs, and how do these relate to the mechanism of ion-transport? 3. Can we uncover the cellular activities of CPIs – perhaps even “dark” activities that do not involve ion-transport?        We will pioneer a CPI-synthesis-approach based on the ability to recycle complex components from highly abundant CPI-family members. To do so, we will develop novel chemical transformations to deconstruct these molecules which may find broader use in a world that is increasingly focused on how to preserve resources. We will provide the first real experimental characterization of the molecular mechanism by which CPIs mediate ion transport by using ultrafast surface-sensitive spectroscopy on membrane-resident CPIs along with unprecedented structural insight using ultra-high field NMR. Finally, we will use an image-based screening technology called morphological profiling to reveal completely new cellular activities of the CPIs.
CORRECTION OF SATURATION BANDING ARTIFACTS IN MAGNETIC RESONANCE IMAGING

Systems and methods for correcting saturation banding artifacts in magnetic resonance imaging in which artifact and reference calibration scans are used to create one dimensional or two dimensional correction profiles, which are subsequently applied to actual diagnostic imaging scans to correct the saturation banding artifacts.
Holographic data-storage medium

In an example holographic data storage medium, which has a polymer film which serves as a storage layer and can be changed locally by heating, the polymer film is set up as a top layer of the data storage medium. Arranged underneath the polymer film is an absorber layer which has an absorber dye. The absorber dye is set up to at least partly absorb a write beam serving to put information in and to discharge the heat produced in the process at least partly locally to the polymer film. In an advantageous refinement of the example data storage medium, there is an adhesive layer underneath the absorber layer and a partly transparent reflective layer between the polymer film and the absorber layer.
Tourist Event of Porto and North

Rally de Portugal 2017 (18 to 21 May 2017) takes place in 13 Municipalities of the North of Portugal and ensures the added value of an event of great international notoriety and gives great visibility to the territory, generating 1 million viewers, 900 hours of national and international television viewing, for an audience of 67 million people, with 50 % of the viewers of the international market (Spain 40 %) remaining 3 or more nights in the region.
TU-G-211-01: New Member Symposium

As a new member of the AAPM, it's easy to feel overwhelmed by the size and complexity of the association and to be unaware of the benefits and opportunities available to members. At this year's AAPM national meeting in Charlotte, we will host a New Member Symposium, where you can learn more about the organization, member resources, opportunities to get involved, and about topics of particular interest to new professionals. We encourage you to take advantage of this great opportunity to learn valuable information and to grow your professional network. Following an introduction from Dr. Gary A. Ezzell, the AAPM President; Michael Woodward of the AAPM staff will provide a crash course on the AAPM structure and organization, as well as some pointers on navigating the website. Next will be Dr. Michael Mills presenting on the current state of the U.S. Medical Physics Workforce, Staffing, Supply & Demand, and Limited Residency slots. Registered attendees will receive a raffle ticket for entry in a drawing to win a complimentary registration for the 2013 Annual Meeting in Indianapolis. In addition, all new members who register for the Symposium will receive a drink ticket good for one complimentary beer served after the New Member Symposium during the social with committee chairs from 4 AAPM Councils: Science, Education, Professional, and Administrative.
Beyond Federalism: Estimating and Explaining the Territorial Structure of Government

This article suggests that the basic distinction between federal and unitary government has limited as well as served our understanding of government. The notion that variation in the structure of government is a difference of kind rather than degree has straight-jacketed attempts to estimate the authority of intermediate government. One result has been the claim that a country’s footprint, not its population, is decisive for government. Analyzing data for thirty-nine countries since 1950, and comparing our own findings with those of alternative measurements, we find evidence for the causal effect of population. This can be theorized in terms of a trade-off between responsiveness to soft information and per-capita economies in public good provision. The structure of government—the allocation of authority across general purpose jurisdictions—is a deep and puzzling phenomenon. Philosophers from Hobbes to Madison to Ostrom, and political scientists from Riker and Elazar to Lijphart have sought to explain why some countries are, or should be, decentralized while others are centralized. Since the creation of the United States, government structure has been conceived as a basic choice between a unitary and a federal system. A unitary system is one in which decision making may be deconcentrated or even decentralized, but final authority rests with the center. A federal system, by contrast, disperses authority between ‘‘regional governments and a central government in such a way that each kind of government has some activities on which it makes final decisions’’ (Riker 1987, 101). Most importantly, regions or their representatives can veto constitutional reform. Each conception is rooted in a coherent, but opposing, philosophy: ‘‘The contrast between Hobbes’ formulation of the institutions of government and that formulated in the American experiments in constitutional choice suggests that fundamentally different approaches exist for the organization of governance in human societies. In the one, a single center of authority, the sovereign, is designed
Improved Topotactic Reactions for Maximizing Organic Coverage of Methyl Germanane

The topotactic transformation of Zintl phases such as CaGe2 into organic-terminated germanium graphane analogues using haloalkanes is a powerful route for generating new 2D optoelectronic and spintronic building blocks. However, uniform ligand coverage is necessary for optimizing the properties and stability of these single-atom-thick frameworks. Here, we compare the effectiveness of different topochemical methods to maximize methyl-termination in GeCH3. We show that a previously developed CH3I/H2O phase transfer route produces a small percentage of partially oxidized germanane. The partially oxidized termination is readily removed upon HCl treatment, which leads to Ge–Cl termination, but rapidly reoxidizes after exposure to the ambient atmosphere. We then show that a one-pot route with CH3I in distilled CH3CN solvent and at least six equivalents of H2O results in no oxidation. The GeCH3 prepared from this one-pot route also has an increased −CH3/–H ratio of termination from ∼90:10 to ∼95:5, is air-stable...
COPPER ALLOY FOR HEAT EXCHANGER TUBE

An alloy comprising copper, nickel, tin and, optionally, phosphorus which can be used in, for example, a copper alloy tube for heat exchangers that provides excellent fracture strength and processability for reducing the weight of the tube and for use in high pressure applications with cooling media such as carbon dioxide.
Investigation on the Effect of Airspeed and Altitude to Phugoid Mode of a Small Unmanned Blended Wing-Body Aircraft with Canard as a Longitudinal Control Surface

Phugoid mode is a lowly damped, low-frequency oscillatory motion representing vertical translation usually related to kinetic and potential energy interchange. MIL-F-8785C standard has ruled out qualitative specification requirements on measurement of flying and handling qualities of piloted aircraft. For phugoid mode, these requirements lie in the value of its damping ratio. Small aircraft is sensitive to atmospheric conditions and poor phugoid mode performance is observed in many unmanned aircraft. This paper discusses the effect of airspeed and altitude to phugoid mode of small, unmanned blended wing-body (BWB) aircraft named Baseline-II E-2. Baseline-II is a low subsonic, remotely-piloted UAV used to study the behaviour of a BWB-type aircraft. The case presented here is an E-2 version in which a specifically-designed canard is incorporated as its longitudinal control surface. Five Category B flight cases (airspeeds) per altitude-case, and three altitude cases (low, medium and high) are studied. Model-N dynamic model is introduced here to become the basis of flight simulation. The model is compared to models derived by other authors and approximation equations. The mean of simulating phugoid behaviour is using state-space representation of the aircraft using Matlab SIMULINK. The computations show that Baseline-II E-2 undamped natural frequency of phugoid mode is inversely-proportional to airspeed and reduces as altitude increases. These have adverse effect on its damping ratio that increases near parabolically when the aircraft flies faster, and reduces when it climbs up. The cause of these trends is looked into in detail and issues concerning Baseline-II E-2’s unsatisfactory and unstable phugoid mode oscillation at low speed are addressed.
Personalised prognostic models to improve well-being and return to work after neck and low back pain

Neck and low back pain (NLBP) are leading causes for years lived with disability in Europe and worldwide. About 70% of all adults experience NLBP at some point in their lives, and both conditions are among the top ten in terms of overall disease burden expressed as disability adjusted life years. Management of NLBP is a difficult challenge for healthcare professionals since their decisions have a decisive impact on the patient’s future health and welfare, as well as on the economic burden on the public and private healthcare systems. However, health professionals often lack appropriate information to tailor the management and follow-up of individual patients and to predict the outcome of a certain treatment. At European level, diverse research initiatives are undergoing at this moment for tackling NLBP from diverse angles, including biomarkers (PainOmics), pain self-management (selfBACK), lifestyle and workplace conditions (AHA), or patients stratification (STarT Back). Back-UP project provides a wider vision of NLBP, bringing together the research groups that are leading these and other innovative approaches to create a prognostic model to underpin more effective and efficient management of NLBP based on the digital representation of multidimensional clinical information and on simulations of the outcomes of possible interventions. Patient-specific models will provide a personalised evaluation of the patient case, using multidimensional health data from the following sources: personal, health, psychological, behavioural, and socioeconomic factors related to NLBP; biological patient characteristics, including musculoskeletal structures and function, and molecular data; and workplace and lifestyle risk factors. Back-UP will provide health, well-being and economic benefits to different user profiles (clinicians, employers / insurance companies and patients) and will create a channel for sharing information during the rehabilitation and return to work process.
Method for producing a roller shutter box

Production of a roller blind casing outside of a building opening (4) comprises placing a support (2) on wall parts (3) which laterally delimit the building opening, and placing molded bricks (1) on the support which has a recess for receiving the roller blind. The bricks are individually placed after each other. The recess is arranged laterally over a bearing surface by which the bricks are placed on the support. An Independent claim is also included for a system for producing a roller blind casing. Preferred Features: The bricks are joined to the support using an adhesive mortar. After producing the roller blond casing, side parts are applied.
INHIBITORS OF PI3 KINASE

The present invention relates to compounds of Formula I, II or III or a pharmaceutically acceptable salt thereof; methods of treating diseases or conditions, such as cancer, using the compounds; and pharmaceutical compositions containing the compounds, wherein the variables are as defined herein.