SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Anti-inflammatory effects of linezolid on carrageenan-induced paw edema in rats

The immunomodulatory activity of linezolid has recently been reported using in vitro experimental models. However, the anti-inflammatory activity of linezolid has not yet been demonstrated using in vivo experimental models. Therefore, the aim of the present study was to demonstrate the anti-inflammatory activity of linezolid and other anti-MRSA agents using the carrageenan-induced rat paw edema model. The pretreatment with 50 mg/kg linezolid significantly suppressed edema rates, compared with control (5% glucose), with edema rates at 0.5 and 3 h after the administration of carrageenan being 17.3 ± 3.5 and 30.8 ± 3.0%, respectively. On the other hand, edema rates were not suppressed by the pretreatments with 50 mg/kg vancomycin, teicoplanin, arbekacin, and daptomycin. Furthermore, we demonstrated that linezolid exhibited anti-inflammatory activity in a concentration-dependent manner. These effects were observed at linezolid concentrations that are achievable in human serum with conventional dosing. In conclusion, the results of the present study suggest that the anti-inflammatory activities of linezolid, in addition to its antimicrobial effects, have a protective effect against destructive inflammatory responses in areas of inflammation.
Prevalence of third molars and pathological changes related to them in dental medicine.

The purpose of this study was to determine the prevalence of third molars in terms of respondents' age. Furthermore it was desired to determine the extent of the manifestation of pathological changes, such as caries, apical lesions, and alveolar bone resorption. This study was based on 500 OPGs of patients from the Faculty of Dentistry, University of Zagreb. Patients were divided into seven age groups. The total number of molars, the number of cavities on remaining molars, the quality of endodontic treatment and the evaluation of their performance and presence of periapical lesions was analyzed. As apart of the periodontal status, the number of inadequate fillings, the number of damaged furcations and bone resorption was analyzed. The statistical analysis was performed by means of STATISTICA 7 statistical package (StatSoft, Tulsa, USA). The correlation between the total number of molars and the age of patients was analyzed by means of Spearman's correlation to the level of significance of 0.05. The number of first, second and third molars significantly decreased in higher age groups. The prevalence of caries in third molars as compared to first and second molars was generally lower, third molars were endodontic treated at least. Assessment of involved furcations showed that the lowest percentage of 8% was found in third molars. The majority of all remaining molars had bone resorption of 1-3 mm.
DRIVE SYSTEM

The invention relates to a drive system (10), wherein: a drive shaft (1) and an output shaft (2) as well as a second motor (12), together with the second rotor shaft (4) thereof, are arranged coaxially in a first shafting (21); a multi-stage cross-drive steering transmission (15) of the drive system (10), together with a sun gear (17), a ring gear (18) and a planetary carrier (19), is designed solely as a three-shaft planetary gear stage, which is arranged in a second shafting (22) parallel to the first shafting (21); and a first motor (11) is arranged in a third shafting (23) together with the first rotor shaft (3) thereof, said third shafting being parallel to the first shafting (21) and to the second shafting (22).
CARBON balance drafting and new resources management tools according to Kyoto PROtocol (CARBON-PRO)

Areas used by agriculture and forestry are important for storing atmospheric CO2, which is a by-product of employing conventional sources of energy. It is also one of the greenhouse gases mainly responsible for global climate change. An adequate management of agriculture and forestry resources might help to reduce the impact of CO2 emissions. In the Kyoto Protocol some strategies have already been drawn up concerning the positive effects of managing the CO2 sink capacities of forests and areas used by agriculture. These strategies now have to be implemented. As the worldwide dimension of climate change demands solutions beyond national policies, the CADSES space provides a promising field for the application of transnational approaches to manage agricultural and forest systems to improve the carbon balance. The CARBON-PRO project deals with the need for an integrated cross-border management of agriculture and forest resources to implement the demanding environmental policies and standards of the EU. These include negotiations and compensation policies with carbon credits and other policies for reducing the release of CO2 at transnational level as foreseen by the Kyoto Protocol. The project involves seven countries from Central and South-Eastern Europe. Partnership members are administrative bodies, large cities with forests, research centres and forest management bodies.
METHOD FOR THE PREPARATION OF SEVOFLURANE

A method for the preparation of (CF<SUB>3</SUB>)<SUB>2</SUB>CHOCH<SUB>2</SUB>F (Sevoflurane) is presented, which comprises providing a mixture of (CF<SUB>3</SUB>)<SUB>2</SUB>CHOCH<SUB>2</SUB>Cl, potassium fluoride, water, and a phase transfer catalyst and reacting the mixture to form (CF<SUB>3</SUB>)<SUB>2</SUB>CHOCH<SUB>2</SUB>F.
Colorimetric precision nanodiagnostics made fast and affordable

There is a need for cost-effective molecular point of care diagnostic tools to provide better healthcare to patients and better agility to our healthcare system. And what about going one step further by extending the limits of molecular diagnostics to the nano-scale?
The market needs a rapid and definitive answer at entry level. Needs a diagnostic that is capable of screen directly and simply hundreds of samples with low infrastructure and low-grade people, that can rely on existing peripheral infrastructure like peripheral hospital and microscopy centres.
We have developed the nano-technology-based solution NANO4. NANO4 is a fast and user-friendly nano-based diagnostic technology suitable for use at the Point of Need. NANO4 represents a highly specific and sensitive nanotechnology for in vitro molecular diagnostics. It uses gold nano-probes to recognize the complementary DNA/RNA strand and yield a colour output that allows for quick decision making.
Molecular diagnosis is a multi-million Euro market and making use of our SME Instrument Phase 1 Feasibility Study, we defined our go-to-market roadmap for our first disruptive products: NANO4 TB for Tuberculosis, and NANO4 CML for Chronic Myeloid Leukaemia, including industrial scale-up and CE mark.
We have already established partnerships with distributors in Europe and Brazil, and our technology has been referenced by FIND as a promising new solution for TB diagnosis. We have also established a connection with the World Health Organization, in order to obtain an endorsement as soon as we receive the CE mark.
NANO4 was founded in end 2015, and we have raised €200.000 from Business Angels and have already begun our operations to take our products to the market, expecting a Series A at the end of 2018.
With the successful conclusion of this project, NANO4 will become one of the few companies in Europe to possess nanotechnology capacities at industrial scale, focused on the life sciences sector.
Almost-Periodic Higher Order Statistic Estimation

In this paper, stochastic processes with higher order statistical functions decomposable into an almost-periodic function plus a residual term not containing finite-strength additive sinewave components are considered. These processes arise in mobile communications when almost-cyclostationary (ACS) processes pass through time-varying channels. They include as special case the generalized almost-cyclostationary processes which, in turn, include the ACS processes. In the paper, the problem of estimating the Fourier coefficients of the (generalized) Fourier series expansion of the almost-periodic component of higher order statistical functions is addressed. Estimators are proposed for cyclic temporal cross moment and cumulants. They are proved to be mean square consistent and asymptotically complex Normal under mild assumptions on the memory of the processes expressed in terms of summability of cross cumulants. Numerical results confirm the theoretical results and the derived rate of convergence to zero of bias and standard deviation of the estimators.
CONNECTION DEVICE BETWEEN HIGH-VOLTAGE ELECTRICAL APPARATUSES

The connection device (10) can be used to provide an electrical connection between two electrical apparatuses (3, 6), both of which can be insulated in a fluid or solid medium, with at least one air connection point (24) being established in said electrical connection. The device (10) comprises an elongate body (7) containing a connector (1) and a conductor (5), both of which are encapsulated. The connector (1) is plug-coupled in female bushings (2) provided for this purpose in the first apparatus (3), while the conductor (5) is connected to the second apparatus (6), with an air connection point (24) being established in the latter connection, such that the connection device (10) guarantees that an insulated, shielded electrical connection is provided between a conductor and an electrical apparatus.
Integrated Environmental Engineering Design Tools for Environmental Values with Business Decision Applications

This paper investigates the alluring connection between business procedure and natural designing methodology on a product offering premise. The creators extend past work on ecological administration apparatuses, utilizing Product Portfolio Matrix examination strategies adjusted to incorporate natural ascribes. The creators show how the customary pivot of piece of the overall industry and market development rate can be rethought as presentation and opportunity from an ecological point of view. A third component, ecological weight, is added to the lattice so natural liabilities are all the while considered in the investigation. The paper likewise shows how ecological investigation can be utilized to make a fruitful move into a more alluring business sector position.
SUBSÍDIO DE CAPITAL DE EXPLORAÇÃO PARA A MARWEL MAIS SP. COM O O.O.

O projeto diz respeito ao apoio do empresário no fornecimento de liquidez financeira e ao apoio às atividades atuais devido às dificuldades financeiras sentidas pelo empresário em resultado do surto de COVID-19. Assistência financeira prestada ao abrigo do programa n.º SA.57015 (2020/N)
Production of commodities by means of processes

Abstract The purpose of this paper is to demonstrate the potential contribution of the flow–fund model to analysing the organisation of production processes by exploring the links with two other levels of analysis: namely, the input–output relations and innovative activity through the development of new knowledge. The flow–fund model focuses on the time dimension of production activities which require specific ‘knowledge how’, in addition to ‘knowledge that’. The flow–fund methodology allows us to analyse the task distributions and the organisation of production processes that are both absent from input–output models. The time-dimension of the flow–fund analysis provides the necessary bridge to explain the co-evolution of organisational settings and new productive knowledge.
Healthy minds from 0-100 years: optimising the use of european brain imaging cohorts

Our main objective is to identify determinants of brain, cognitive and mental health at different stages of life. By integration, harmonisation and enrichment of major European neuroimaging studies of age differences and changes, we will obtain an unparalleled database of fine-grained brain, cognitive and mental health measures of more than 6.000 individuals. Longitudinal brain imaging, genetic and health data are available for a major part, as well as cognitive/mental health measures for extensively broader cohorts, exceeding 40.000 examinations in total. By linking these data, also to additional databases and biobanks, including birth registries, national and regional archives, and by enriching them with new online data collection and novel measures, we will address risk and protective factors of brain, cognitive and mental health throughout the lifespan. We will identify the pathways through which risk and protective factors work and their moderators. Through exploitation of, and synergies with, existing European infrastructures and initiatives, this approach of integrating, harmonising and enriching brain imaging datasets will make major conceptual, methodological and analytical contributions towards large integrative cohorts and their efficient exploitation. We will thus provide novel information on brain, cognitive and mental health maintenance, onset and course of brain, cognitive and mental disorders, and lay a foundation for earlier diagnosis of brain disorders, aberrant development and decline of brain, cognitive and mental health, as well as future preventive and therapeutic strategies. Working with stakeholders and health authorities, the project will provide the evidence base for policy strategies for prevention and intervention, improving clinical practice and public health policy for brain, cognitive and mental health. This project is realized by a close collaboration of small and medium-sized enterprise (SME) and major European brain research centres
Applying relationship anecdotes paradigm interviews to study client–therapist relationship narratives: Core conflictual relationship theme analyses

We describe client-therapist relational narratives collected in relationship anecdotes paradigm (RAP) interviews during psychotherapy and the application of the core conflictual relationship theme (CCRT) method. Changes in clients' and therapists' CCRT in relation to each other are examined and associations between their CCRTs and self-reported ruptures and repairs are explored.Sixty-seven clients and 27 therapists underwent RAP interviews and completed self-report rupture and repair items at early, middle, and late psychodynamic psychotherapy. Client-therapist relationship narratives were rated on the CCRT and the relational interplay within dyads was explored qualitatively.CCRT changes from early to late therapy showed that with time clients perceived the therapist (RO) and the self (RS) more positively, and the therapist perceived the self (RS) less negatively. Some associations were found between tension in the session and clients' and therapists' negative RO and RS. Therapists' reports of alliance repairs were associated with positive RO and RS.Relational narratives that clients and therapists tell in RAP interviews about meaningful interactions between them, enhance our understanding of clients' and therapists' inner experiences during interpersonal dances in the therapeutic relationship. Limitations and directions for future research are discussed, and implications for training are suggested.
Composite mould tool based on 3d printing

COMBO3D proposes to additively manufacture a short fibre reinforced thermoplastic tool with integrated active temperature control, to shorten the cure cycle time and so to focus on the objectives addressing the limitations and implementing the improvements of the state of the art project. By using a robot guided large scale short fibre reinforced plastics extrusion additive manufacturing process the tool can be produced as a single part, directly integrating the temperature control, shortening the lead-time and enabling simple and fast restoration of the tool surface to compensate for the expected lower lifespan. Using a robot-guided process also allows to print the final demonstrator tool in one piece in curved layers (real 3D printing). To ensure tool stability during the curing cycle, short carbon fibre reinforced semi-crystalline high performance thermoplastic PAEK will be used. Commercially available PAEK have a form stability of over 250°C in unreinforced grades and CF filled grades are available with heat deflection temperatures of 315°C and more.
By introducing heating elements in the tool, it can conduct heat to the parts lower surface, in combination with the autoclave or oven, heating it up from both sides. These heating elements can be electrical or fluid channels connected to an external temperature control. Electric heating elements provide higher heat up rates but fluid heating allows to change from heating to cooling mode and hence to also cool the tool. Thereby it is possible to also achieve faster cool down. COMBO3D therefore proposes to use both heating elements in the tool.
The whole development of the printed tool is supported by simulation. The design of the tool will be optimized by implementing the heating and cooling system in a thermal simulation. The manufacturing process simulation supports the printing process by generating knowledge about the temperature distribution during printing and correlating it with path planning.
Alignment of standard-definition and High-Definition maps

Aspects of the disclosed invention relate to alignment of standard definition (SD) maps and high definition (HD maps) which may come from different sources. Responsive to input of a destination, a route to that destination may be defined, and SD map waypoints generated from that defined route. A graph may be generated from the HD map. The waypoints may be matched with nodes and edges in the graph. One or more edges may constitute a segment in the HD map. A plurality of segments are identified to match the route.
Cost-Efficient network for the genetic certification of food quality

SeQfood project aims to provide the first tool for verifiable product authenticity certification and traceability along the food chain; also being the first electronic network for the genetic certification of food products. The invention relies on our proprietary Genowas-GENOMID fingerprinting technology, a smart system for agrifood certification and labeling by means of 2DNA codes which provide reliable, unique and forgery-proof information of identity, composition and geographical origin. Product´s information will be freely available in the SeQfood web, increasing transparency and consumer´s confidence. SeQfood will result on added value for high-quality products, but also simplifying logistics and traceability. Another powerful novelty is that costs and delivery time are comparable to PCR techniques but our solution provides greater information in a one-step assay. SeQfood represents an essential pillar for the company´s growth since by its commercialization the company will be able to penetrate the growing food traceability market and consolidate its position in the fields of genomics, proteomics and metabolomics. To ensure the successful market launch, our company will conduct a robust feasibility study and a business plan where main technical, commercial and financial resources and requirements will be deeply analyzed. SeQfood is in line with one of the present Societal Challenges of the European Commission addressing “Sustainable and competitive agri-food sector for a safe and healthy diet”, since it will serve as the first verifiable, standardized and free-access tool for warranting food safety, quality and traceability from production to consumption, and vice verse. This will improve food fraud prevention while also promoting high-quality authentic products, which is crucial to assure the commercial success of European high-value agrifood products on international markets, as well as to ensure that consumer’ rights and health are protected.
Being safe around collaborative and versatile robots in shared spaces

Increasing demand from the growing and aging population can be assuaged by ever closer safe human-robot collaboration (HRI): to improve productivity, reduce health limitations and provide services. HRI and safety are both major topics in the Work Programme. Safety regulations will be a barrier to cobot deployment unless they are easy to access, understand and apply. COVR collates existing safety regulations relating to cobots in e.g. manufacturing and fills in regulatory gaps for newer cobot fields e.g. rehabilitation to present detailed safety assessment instructions to coboteers. Making the safety assessment process clearer allows cobots to be used with more confidence in more situations, increasing the variety of cobots on the market and the variety of services cobots can offer to the general population.
TRYG provides a one-stop shop which uses a common approach to safety assessment and is valid across all fields and applications. TRYG will provide clear and simple online access to best-practice safety testing protocols via a user-friendly decision tree, guided by questions about the cobot and its intended behaviours. Resulting application-specific testing protocols specify how to assess safety and document compliance with regulations. 
We support coboteers by providing safety-relevant services based in well-equipped facilities at each partner site. TRYG services cover all stages of cobot development from design through final system sign-off to safety in use and maintenance, provided through consultancy, risk analysis, actual testing, workshops, courses, demonstrations, etc. – all designed to inspire people to increase cobot safety.
All TRYG elements will be beta-tested by external cobot developers etc. financed by FSTP. By using project elements  “live”, these FSTP beneficiaries not only develop their cobots further towards market, but also contribute their knowledge to the TRYG system and provide valuable feedback to both partners and standards developers.
Re: Postoperative Care Using a Secure Online Patient Portal: Changing the (Inter)Face of General Surgery

available at http://www.ncbi.nlm.nih.gov/pubmed/25775063 Editorial Comment: This study further underscores the importance of using a universal checklist for all patients undergoing surgery. The authors determined the effect of using a sign in, time out and sign out checklist for patients at 5 academic and community hospitals. It was next determined if the checklist was incomplete, partly complete or fully completed. Postoperative complications were then analyzed and compared among groups. Surprisingly full completion of the checklist was observed in only 62% of cases. Although checklist completion did not affect mortality, the risk of postoperative complications was significantly decreased when all components of the checklist were completed (16.9% vs 11.2%). Also it was determined that 14% of the complications could have been prevented if the full checklist had been implemented. Thus, it seems that careful attention and meticulous detail when completing all components of universal checklists for patients undergoing surgery are of benefit to our patients undergoing surgery.
Method for treating fly ash

A method for treating fly ash from incineration plants having at, least one combustion chamber includes precipitating fly ash in a dust separator, and treating the fly ash using a gaseous reducing agent at a temperature between 600 and 700° C. so as to selectively convert a metal sulfate into at least one of a sulfide and a metallic form of the metal sulfate.