SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Benefit risk and cost ratios in sustainable food and health policy: Changing and challenging trajectories.

There is benefit, risk and cost in all that we do, but when it comes to food, we expect that it will benefit our health, be available, safe to eat and affordable. But as climate change and demographic shifts through displacement and ageing gather momentum, the emphases on each of benefit, risk and cost will alter. That we are ecological beings whose health and wellbeing are ecosystem-dependent, must now be the underpinning framework for risk management. Loss of natural environment and biodiversity represents reduced nutritional and health resilience, which will need to be factored in to risk assessment and management with climate change. This is proving a problematic risk communication challenge. Previously desirable food and food pattern recommendations will be tempered by substantial sustainability, availability, safety, affordability, equity and ethical considerations. Future workforces will need to ensure basic livelihoods (food, water, shelter, clothing, healthcare, education, communication, essential transport, resource management and effective governance) and with risk minimisation. Cost appraisal will have less to do with monetisation and more to do with resource management in accordance with equity and ethical principles. Communities could adopt Liveability Units (LU) for traceability and community-based transactions, as a currency for a more sustainable future, encouraging and enabling food and health system viability. Open source food and health systems, supported by LU matrix (bar code or QR) scanning with smartphones could be widely available for individual, household and community benefit, risk and cost management. The risk is remoteness from food's origins and megadata commercialisation.
SVILUPPO BI-MU

F.LLI NAVA S.R.L. ÃÂ ÃÂ¿ UNA AZIENDA SPECIALIZZATA NELLA PRODUZIONE DI PRESSE OLEODINAMICHE UTILIZZATE IN DIVERSI SETTORI PRODUTTIVI: AUTOMOTIVE, MEDICALE, CASALINGO, AERONAUTICO, MOTOCICLO ECC., DOVE TROVIAMO I DESTINATARI DI UNA GAMMA VARIEGATA DI PRESSE PER IMBUTITURA, PER IDROFORMATURA, PER ELASTOFORMATURA, PER RADDRIZZATURA. L'AZIENDA HA PIANIFICATO UN PROGRAMMA DI SVILUPPO BASATO SULLA PARTECIPAZIONE ALLE PROSSIME DUE EDIZIONI DELLA FIERA BI.MU, CHE SI SVOLGE NEL MESE DI OTTOBRE CON CADENZA BIENNALE. DAL 14 AL 17 OTTOBRE 2020, A FIERAMILANO RHO, ANDRÃÂ ÃÂ IN SCENA LA 32ESIMA EDIZIONE DI BI-MU, LA PIÃÂ ÃÂ¹ IMPORTANTE MANIFESTAZIONE ITALIANA, DI RESPIRO INTERNAZIONALE, DEDICATA ALL'INDUSTRIA COSTRUTTRICE DI MACCHINE UTENSILI AD ASPORTAZIONE, DEFORMAZIONE E ADDITIVE, ROBOT, DIGITAL MANUFACTURING E AUTOMAZIONE, TECNOLOGIE ABILITANTI E SUBFORNITURA CON FOCUS SU 'PINO INDUSTRIA 4.0' .IL PROGETTO QUINDI RISPETTA LA FINALITÃÂ ÃÂ DEL BANDO ED ÃÂ ÃÂ¿ FINALIZZATO A PROMUOVERE L
MaxPHOS Ligand: PH/NH Tautomerism and Rhodium- Catalyzed Asymmetric Hydrogenations

MaxPHOS is an active and robust P-stereogenic ligand for asymmetric catalysis. The presence of an NH bridge between the two phosphine moieties allows the NH/PH tautomerism to take place. The neutral ligand, in which the NH form predominates, is an air-sensitive compound. However, protonation of MaxPHOS leads to the stable PH form of the ligand, in which the overall positive charge is distributed on both P centers. This protonation turns the MaxPHOS⋅HBF4 salt 3 into an air-stable compound both in the solid state and in solution. The salt 3 is also a convenient precursor for the preparation of rhodium(I) complexes by direct ligand exchange with the complex [Rh(acac)(cod)]. Finally, the corresponding rhodium(I)-MaxPHOS complex was tested in the asymmetric hydrogenation of a wide range of substrates. The complex proved to be a highly selective and robust system in these reactions.
Developing a New Management Model for the Built Environment: The Built Environment Management Model BEM2 and BEM3

The Real Property Portfolio has significant financial and operational impact in most organizations. Yet in many organizations there is a gap and disconnect between the various build environment functions. Currently, there is no easily accessible assessment tool available to stu dy the efficiency of Facility Management processes and to compare maturity benchmarks. The aim of the project was to develop an “industry independent” framework that can effectively classify and compare existing FM/RE practices within and across industry boundaries. Researcher investigated and evaluated current FM/RE management models and analysis tools and developed an assessment tool to measure Facility Management capability of an organization. The “Built Environment Management Model” (BEM2) is a process framework for FM/RE, which is extended into the “Built Environment Management Maturity Model” (BEM3) to measure FM/RE maturity. Using the tool, the research team analyzed the FM capability of more than 50 organizations with major real estate portfolios in the US and Europe. The resulting capability profiles provide an overview of current practices in Facilities Management. The profiles also allow organizations to develop “winnable” improvement initiatives to increase the strategic value of the FM function.
Multi-Layered integration of motivated actions and their outcomes in basal ganglia circuits

We cross the street when the traffic light is green (action initiation), and we wait if it is red (action suppression), both in order to reach a goal across the street, such as getting an ice cream (rewarding) or insect-repellant to avoid a mosquito bite (aversive). Such action control is dysfunctional in several psychiatric disorders. For example, action initiation and suppression are impaired in patients suffering from depression and impulsivity, respectively. Thus, improving our incomplete understanding of the neural basis of action control has translational value, specifically how action outcome valence (rewarding or aversive) interacts with brain mechanisms of action control (i.e., initiation or suppression). The direct and indirect output pathways of the basal ganglia are strongly implicated in action initiation and suppression, respectively, and receive modulating input from dopamine and serotonin neurons, which are implicated in processing rewarding and aversive stimuli, respectively. I hypothesize that the anatomical and functional integration of these opposing systems supports action control as well as constitutes a neural interface for the interaction of action control and outcome valence. I propose to use a set of innovative and inter-disciplinary approaches that include monitoring neuronal ensemble activity with calcium imaging using implantable, miniaturized fluorescence microscopes and simultaneous optogenetic manipulation in novel transgenic rats performing in a tailor-made behavioral paradigm. I aim to understand the neural mechanisms in the basal ganglia that crucially govern the control over actions with different outcome valences. My anticipated results will inform future research and potentially treatment of psychiatric disorders such as depression and impulsivity disorders. Further, this fellowship will strengthen my position as an independent researcher and increase my chances for a tenure-track position at a European research institution.
The elimination of human African trypanosomiasis: Achievements in relation to WHO road map targets for 2020

In the 20th century, epidemics of human African trypanosomiasis (HAT) ravaged communities in a number of African countries. The latest surge in disease transmission was recorded in the late 1990s, with more than 35,000 cases reported annually in 1997 and 1998. In 2013, after more than a decade of sustained control efforts and steady progress, the World Health Assembly resolved to target the elimination of HAT as a public health problem by 2020. We report here on recent progress towards this goal.With 992 and 663 cases reported in 2019 and 2020 respectively, the first global target was amply achieved (i.e. fewer than 2,000 HAT cases/year). Areas at moderate or higher risk of HAT, where more than 1 case/10,000 people/year are reported, shrunk to 120,000 km2 for the five-year period 2016-2020. This reduction of 83% from the 2000-2004 baseline (i.e. 709,000 km2) is slightly below the target (i.e. 90% reduction). As a result, the second global target for HAT elimination as a public health problem cannot be considered fully achieved yet. The number of health facilities able to diagnose and treat HAT expanded (+9.6% compared to a 2019 survey), thus reinforcing the capacity for passive detection and improving epidemiological knowledge of the disease. Active surveillance for gambiense HAT was sustained. In particular, 2.8 million people were actively screened in 2019 and 1.6 million in 2020, the decrease in 2020 being mainly caused by COVID-19-related restrictions. Togo and Côte d'Ivoire were the first countries to be validated for achieving elimination of HAT as a public health problem at the national level; applications from three additional countries are under review by the World Health Organization (WHO).The steady progress towards the elimination of HAT is a testament to the power of multi-stakeholder commitment and coordination. At the end of 2020, the World Health Assembly endorsed a new road map for 2021-2030 that set new bold targets for neglected tropical diseases. While rhodesiense HAT remains among the diseases targeted for elimination as a public health problem, gambiense HAT is targeted for elimination of transmission. The goal for gambiense HAT is expected to be particularly arduous, as it might be hindered by cryptic reservoirs and a number of other challenges (e.g. further integration of HAT surveillance and control into national health systems, availability of skilled health care workers, development of more effective and adapted tools, and funding for and coordination of elimination efforts).
Persuasive Style and its Realization Through Transitivity Analysis: A SFL Perspective

Abstract Leech & Short (2007) claim that examining the language of a literary text can lead to a fuller understanding of the text and thus appreciation of the writer's artistic achievement. Accordingly, this paper explores the relationship between linguistic structures and socially constructed meaning in a literary text. Drawing on Halliday's transitivity framework rooted in Systemic Functional Linguistics, the paper particularly attempts to reveal the persuasive style of the short story entitled ‘Animal Farm’ by George Orwell (1945) from a semantic-grammatical point of view. In effect, it seeks how the persuasive style is realized through the process types (material, mental, verbal, existential, relational, and behavioral) which are part of the ideational function. To this end, the verbal phrases (process types) of this story were analyzed and the results indicated that the material process was the most frequent one among the processes. The mental, verbal, existential, behavioral, and relational processes respectively followed the material process; although, as far as frequency was concerned, a drastic difference was observed between the material process and the rest of the processes. Following the persuasive style of this story, the characters were assumed to be convinced to choose some actions and avoid others. The high frequency of the material process types revealed that they certainly did what they were told to; in other words, their persuasion was expressed through acting upon what they were asked to. The conclusion drawn is that to persuade others, confronting them with the possibilities and expanding their understanding of themselves and their lives via asking them to act upon the advice and make the changes themselves (the material process) prove to be effective than involving their emotions (the mental process) and pushing certain words into their minds (the verbal process).
pMD-Membrane: A Method for Ligand Binding Site Identification in Membrane-Bound Proteins

Probe-based or mixed solvent molecular dynamics simulation is a useful approach for the identification and characterization of druggable sites in drug targets. However, thus far the method has been applied only to soluble proteins. A major reason for this is the potential effect of the probe molecules on membrane structure. We have developed a technique to overcome this limitation that entails modification of force field parameters to reduce a few pairwise non-bonded interactions between selected atoms of the probe molecules and bilayer lipids. We used the resulting technique, termed pMD-membrane, to identify allosteric ligand binding sites on the G12D and G13D oncogenic mutants of the K-Ras protein bound to a negatively charged lipid bilayer. In addition, we show that differences in probe occupancy can be used to quantify changes in the accessibility of druggable sites due to conformational changes induced by membrane binding or mutation.
SANITARY FITTING WITH AN ELECTRICAL OPERATING DEVICE, WHICH HAS AT LEAST ONE CAPACITIVE SENSOR

The invention describes a sanitary fitting with an electrical operating device, which has at least one capacitive sensor (1) with at least one operating region (3). The operating region (3) comprises a support layer (7), which is composed of an electrically insulating material, and an at least partially electrically conductive sensor layer (9) which is functionally connected to an electrical control unit. The sensor layer (9) is arranged on that side of the support layer (7) which is remote from an operating side of the operating region (3), and is connected to the control unit via an electrically conductive conduction layer (23).
Age-Related Changes in Postural Responses to Backward Platform Translation

The aim of the study was to investigate age-related changes in postural responses to platform translation with 3 various velocities. We focused on the influence of linear velocity using the smoothed profile of platform acceleration (till 100 cm.s−2). Eleven healthy young (20-31 years) and eleven healthy elderly (65-76 years) subjects were examined. The subjects stood on the force platform with their eyes closed. Each trial (lasting for 8 sec) with different velocity (10, 15, 20 cm.s−1) of 20 cm backward platform translation was repeated 4 times. We have recorded displacements of the centre of pressure (CoP) and the EMG activity of gastrocnemius muscle (GS) and tibialis anterior muscle (TA). The results showed increased maximal values of CoP responses to the platform translation. There was also observed a scaling delay of CoP responses to platform translation with different velocities in elderly. The EMG activity of GS muscle during backward platform translation was of about similar shape in both groups during the slowest platform velocity, but it increased depending on rising velocity. EMG activity of TA was not related to the platform velocity. Early parts of postural responses showed significant co-activation of TA and GS muscles of elderly. It is likely that elderly increased body stiffening in order to help their further balance control.
Insights into the clinical and functional significance of cardiac autonomic dysfunction in Chagas disease

INTRODUCTION: Exclusive or associated lesions in various structures of the autonomic nervous system occur in the chronic forms of Chagas disease. In the indeterminate form, the lesions are absent or mild, whereas in the exclusive or combined heart and digestive disease forms, they are often more pronounced. Depending on their severity these lesions can result mainly in cardiac parasympathetic dysfunction but also in sympathetic dysfunction of variable degrees. Despite the key autonomic effect on cardiovascular functioning, the pathophysiological and clinical significance of the cardiac autonomic dysfunction in Chagas disease remains unknown. METHODS: Review of data on the cardiac autonomic dysfunction in Chagas disease and their potential consequences, and considerations supporting the possible relationship between this disturbance and general or cardiovascular clinical and functional adverse outcomes. RESULTS: We hypothesise that possible consequences that cardiac dysautonomia might variably occasion or predispose in Chagas disease include: transient or sustained arrhythmias, sudden cardiac death, adverse overall and cardiovascular prognosis with enhanced morbidity and mortality, an inability of the cardiovascular system to adjust to functional demands and/or respond to internal or external stimuli by adjusting heart rate and other hemodynamic variables, and immunomodulatory and cognitive disturbances. CONCLUSIONS: Impaired cardiac autonomic modulation in Chagas disease might not be a mere epiphenomenon without significance. Indirect evidences point for a likely important role of this alteration as a primary predisposing or triggering cause or mediator favouring the development of subtle or evident secondary cardiovascular functional disturbances and clinical consequences, and influencing adverse outcomes.
ROTATABLE WINDOW PANE ASSEMBLY AND METHOD OF REPOSITIONING

A rotatable window pane assembly (9) and method of repositioning the same is disclosed in which the window pane assembly (9) comprising a frame (7) and at least one window pane (8) is rotatably supported in a fixed frame (7) from a first position, such that the at least one window pane (8) is parallel to an aperture defined by the fixed frame (7), to a second position, such that the at least one window pane (8) is parallel to the aperture defined by the frame (7) and a second surface of the at least one window pane (8) faces the outside, or from a second to first position. A seal assembly (15) comprising a seal frame (16) and at least one pliable seal (23) carried is located on the inside with respect to the fixed frame (7) and is pivotally displaceable independently of the position of the window pane assembly (9), from a closed position in which the seal frame (16) is parallel and adjacent to the aperture defined by the interior surface of the fixed frame (7) to an open position in which the seal frame (16) is spaced from and at an angle to the aperture.
Evaluating the Emergence of Reverse Intraverbals Following Intraverbal Training in Young Children with Autism Spectrum Disorder

The purpose of the proposed study was to replicate and extend prior research on intraverbal training by evaluating whether teaching sets of original and reverse intraverbals from the same category (e.g., animal sounds) would result in the emergence of novel, reverse intraverbals. Three children with autism spectrum disorder participated in the study. We used a multiple baseline across categories design with a constant-series control to evaluate the effects of training original and reverse intraverbals on subsequent trained and untrained reverse intraverbals. Copyright © 2015 John Wiley & Sons, Ltd. Behavior-based language interventions are often grounded in Skinner’s (1957) analysis of verbal behavior. Skinner’s unit of analysis is the verbal operant, and he proposed seven verbal operants (e.g., echoics, mands, and intraverbals) that are defined by distinct antecedents and consequences. Skinner (1957) defined the intraverbal as the verbal operant that is controlled by a verbal stimulus that lacks point-to-point correspondence between the stimulus and the response. An example of an intraverbal response includes saying, ‘I’m seven’, following the antecedent verbal stimulus ‘How old are you?’ Correct intraverbal responses are typically maintained by socially mediated reinforcement (e.g., praise) for early language learners, which may lead to additional opportunities for social interactions across various settings. Intraverbal behavior plays an important role in conversational skills and early social interactions. Individuals with autism spectrum disorder (ASD) often fail to acquire an intraverbal repertoire; therefore, they do not have the prerequisite verbal
METHOD AND SYSTEM FOR INTEGRATED ASSET MANAGEMENT UTILIZING MULTI-LEVEL MODELING OF OIL FIELD ASSETS

A method for creating an integrated asset management system for an oilfield, the method including: creating a plurality of models representing asset components each model having more than one levels of detail; connecting the more than one models to communicate with one another to create an integrated asset management system; selecting the levels of detail for the more than one models; and performing an analysis on the integrated asset management system utilizing the selected levels of detail to predict a characteristic of the integrated asset management system.
Antimicrobial activity, phytochemical profile and trace minerals of black mulberry (Morus Nigra L.) fresh juice

In the present work, the fresh juice of black mulberry (Morus nigra) was tested for antimicrobial activity against various pathogenic microorganisms. Total antioxidant contents, total phenolic contents, total anthocyanins, trace minerals, total acid contents, total solids and ascorbic acid content were also evaluated. The results showed good antimicrobial activity both for Gram- positive and Gram-negative bacteria, with highest zones of inhibition for Bacillus spizizenii (19.68 mm, Gram-positive) and Pseudomonas aeruginosa (19.87 mm, Gram-negative). The black mulberry juice was rich in ascorbic acid (23.45 mg/100 g), had low overall acid content (1.60 %) and had 19% total soluble solids. The average total anthocyanins and total phenolic contents of black mulberry juice were 769 µg/g of cyanidin 3-glucoside equivalent (Cy 3gly) per gram and 2050 µg of gallic acid equivalent (GAE) per gram of fresh juice. The average antioxidant activity (Trolox equivalent, TE) of fresh juice was 14.00 µmol/g according to a FRAP assay and 20.10µmol/g according to a DPPH assay. The fresh juice was also rich in a variety of trace minerals.
System for Planning and Performing Staging of Medical Investigations for Diagnosis

Abstract The selection, planning and realization of medical examinations for pre-diagnosis are carried out by physicians over long drop-down lists. Tests which are unnecessary or need to be done in the next stages, cause significant costs for hospitals and affect the quality of the results. In this paper, we propose a system that transforms the established protocols for pre-diagnosis examinations into a personalized finite state machine and executes all steps in the protocol by interacting with patients, physicians and stakeholders with the physician’s start command. For the proposed system, a language has been created to identify precisely the pre-diagnosis protocols and stages. A has been created in order to retrieve protocol definitions from users and convert them to computer language. This interface allows a technically non-expert user to easily define protocols into the database by providing drag and drop graphical flow elements. The system performs the execution of the protocol by producing a Finite State Machine with a timeout and timing functions, which can produce outputs as well as the inputs for a given patient and selected protocol. Messages produced by the system for physicians, patients or stakeholders are sent as notifications via mobile devices. In this way, physicians can watch the execution of the protocols in real time, physicians are given valuable time, standardization and coordination are provided between physicians and hospitals, unnecessary examinations are excluded and necessary ones are included in the validation process. The unnecessary medical examinations are prevented and hospitals provides significant financial benefits. Also duration of the diagnosis is minimized by follow-up of the results.