SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Discovering susceptibility genes to rhizoctonia solani in rice as breeding targets for sheath blight disease resistance

Rice is a main staple food providing more than 50 percent of the world’s calories intake. However, grain yield and quality are drastically reduced by the sheath blight disease (ShBD), the second most important disease. ShBD is caused by the soilborne, necrotrophic fungal pathogen, Rhizoctonia solani. No rice germplasm providing complete resistance is available, preventing improvement of cultivated rice varieties. Generally, dominant resistance genes are used to generate resistance to pathogens. However, these narrow-spectrum genes can be easily overcome by pathogens. Therefore, the best approach to acquire broad-spectrum resistance is to employ altered susceptibility genes (S genes). S genes encode susceptibility factors, facilitate pathogen infection and support compatibility. The molecular mechanisms underlying susceptibility to R. solani are largely unknown. Recently, it has been recognized that necrotrophic pathogens have a short biotrophic phase during infection. In “RiZeSisT” -Rice rhiZoctonia reSisTance-  I will identify rice S genes that are essential to establish the early (biotrophic) infection of R. solani. I will exploit mutated (incompatible) S gene(s) to generate resistance to ShBD. After this project we will generate non-GMO mutants for improving elite varieties for broad-spectrum resistance to ShBD.
 KeyGene acts at the forefront of new technologies and traits to support the development of new and improved crops. Executing “RiZeSisT” at KeyGene, will enable me to use cutting-edge technologies, bioinformatics & data science expertise and plant-based trait platforms to discover the S genes. This is an innovative strategy that has not been used for this pathosystem. Furthermore, there is a high chance to translate my obtained knowledge to generate resistance to R. solani in additional relevant crops as maize, wheat, barley or soybean. The results of “RiZeSisT” will contribute to meet food security needs for our growing population.
Heparin and heparan sulphate: from sequence determination to therapeutic strategies for parkinson’s disease

Heparin and heparan sulphate (HS) are highly sulfated polysaccharides that reside on the cell surface and extracellular matrix of all mammalian cell types. Understanding their functions has tremendous potential to unlock the next generation of heparin-based diagnostics and therapeutics for multiple diseases including inflammatory and neurological diseases, cancer, and wound healing. Despite this promise, it is very difficult to harness this biomedical potential due to a fundamental technology bottleneck - lack of methods for the sequencing of HS structures to define the natural “HS codes” that underpin many biological functions. HS-SEQ will address this hurdle and will place Europe in the leading position in the emerging field of glycomics of heparin and HS. It is our vision that robust sequencing methods for heparin and HS will only be possible when new instrumentation will be developed that can simultaneously record multiple molecular properties such as molecular weight by mass spectrometry (MS), collisional cross sections (CCS) by ion mobility spectroscopy (IMS) and vibrational properties by gas-phase infra-red (IR) ion spectroscopy. To implement such a platform, large collections of well-defined HS saccharide standards are needed to generate reference databases that can match molecular properties to structural features. To obtain the required collection of HS saccharides, HS-SEQ will develop and implement an automated platform for chemoenzymatic synthesis of such compounds. The synthetic HS saccharides will also provide unique opportunities to develop an antibody toolkit to identify epitopes expressed by cells/tissues. Specific transformational applications of the new technology will be pursued: (i) identify HS codes that promote the generation of dopaminergic neurons from human pluripotent stem cells (hPSCs) for cell replacement therapy in Parkinson’s disease; and (ii) achieve unprecedented in-depth analysis of pharmaceutical and next-generation heparins.
Common Takeover Defenses

This chapter deals with takeover defenses. Takeover defenses are impediments to potential bidders and are designed either to slow own an unwanted offer or force a suitor to raise the bid to get the target's board to rescind the defense. Takeover defenses are designed either to slow the takeover process and give the target firm a chance to strengthen its existing defense or put new ones in place, or raise the total cost to the acquirers of taking over the target. The best defense against unwanted suitors may be advance planning and a strong financial performance. Large public companies routinely review their takeover defenses. Many companies have “stock watch” programs in place at are intended to identify stock accumulations, or stock price movements at reflect an impending takeover attempt. Such programs track trading patterns in a company's stock. Companies require their stock transfer agent to provide up-to-date and accurate stock transfer sheets and to report any unusual movements in stock transfer activity. Stock watch programs routinely review securities and exchange commission (SEC) records for any Schedule 13D filings, which are required when a firm buys more an 5 percent of another firm's stock.
Innovations in Economic Science: French Contribution for the Last 70 Years

In the article some branches of modern economic thought are considered, in which the French researchers have made pioneering contributions. French science is characterized by its Cartesian roots as well as by the ideas of national accounting dating back to Quesnay. Over the past 70 years two parallel paths of these fundamental distinguishing features are clearly visible. One way is formed under the influence of historical, legal and psychological research. It is presented by indicative planning, experimentation in the economy, and theories of justice and regulation. The other way is determined by the inclusion of mathematics, where the French contribution can be seen in such approaches as macroeconometric modeling, the theory of disequilibrium and quantitative finance.
New Evaluation Method for Liquefaction of Ground Using Dynamic Liquefaction Analysis Method and Its Application

AbstractNankai megathrust earthquakes are expected to occur with a return period of approximately 90–200 years along the fault of the Nankai Trough. Because they are interplate earthquakes, it is predicted that they will cause heavy liquefaction damage as a result of the long duration of their ground motion, especially around bay areas with soft deposits. In this study, a numerical analysis was performed for the ground in Osaka City with a hypothetical earthquake in the Nankai Trough region. In the numerical simulation of the dynamic behavior, a liquefaction analysis program was used. To quantify the degree of liquefaction at certain points, an index, named the liquefaction risk index (LRI), was defined and obtained by the weighted integration of the effective stress-decreasing ratio (ESDR) with respect to depth. Moreover, the LRI values were evaluated by data from the 1995 Hyogoken-Nanbu earthquake. It was found that the obtained LRI values were greater than 6.0 for the points at which heavy liquefaction...
Surveillance of maritime surroundings through laser technology

Sensor technologies used today onboard maritime assets provide incomplete surveillance of the surface layer. A prototype Ladar sensor has been developed in recent previous projects that has been demonstrated to be able to properly survey and monitor the surface layer surroundings of vessels, platforms and coastal infrastructures. It represents an unique
heterologation of system technologies and features. This enables enhanced safety, security, environmental monitoring and
reduced operational risks. The ownership of the sensor prototypes (and its related IPR) has been spun-off to a separate entity (named Ladar Ltd) – a subsidiary of G.M.S. Global Maritime Services Ltd – that now is about
developing the business case and commercialization process. This project will focus on the critical decisions that need to be taken at this stage to maximize the value of the Ladar in the maritime market domain. It will analyze the market in relation to the plurality of Ladar applications, purchase power/pricing, dissemination/marketing, production escalation, distribution and various after-sales services. In the ‘traditional shipping market’ the Ladar Ltd business case will follow a ‘disruptive’ business
plan disrupting the traditional vendor based sales offering with a sensor solution congruent to the most advanced of the 'user driven mind' concepts and directly fitting with user/client needs.
INHIBITORS OF GLYCOPROTEIN VI

The Invention provides use of an antibody against platelet glycoprotein VI (GPVI) for the preparation of a medicament for the prevention of intraarterial thrombosis in a Patient characterized by (i) having suffered from an acute coronary or carotid syndrome and (ü)having active intraarterial lesions. The present Invention also provides an antibody against platelet glycoprotein VI (GPVI) for the preparation of a medicament for the manufacture of a medicament for the treatment of diabetes. Further, in vivo and in vivo screening methods for inhibitors or GP VI are provided and inhibitors identified thereby.
99 Privacy Breaches to Beware Of: Practical Data Protection Tips from Real Life Experiences

Data protection laws are new in Singapore, Malaysia, Philippines, Indonesia and Thailand. In Europe, the General Data Protection Regulation (GDPR) — a single law across all of EU – comes into force from May 2018. There are also strict laws in the US that govern the processing of personal data. Over a hundred countries in the world have a comprehensive data protection law and it is very easy for individuals and companies to breach these laws. Data or privacy breaches are on the rise and businesses can be prosecuted under data protection laws. Fines for non-compliance can be from S$1 million in Singapore, up to three years jail in Malaysia, and up to 4% of global revenues for EU countries. The focus on this book is operational compliance. The book is for everyone as all of us in the course of our daily work process personal data. Organised into sections, each idea provides practical advice and examples of how a breach of the law may happen. Examples cover HR, Finance, Admin, Marketing, etc, allowing the reader to relate to his or her own area of work
A highly efficient and eco-friendly electric shower offering health benefits through magnesium sulphate

According to reports by the US ‘National Institutes of Health’ (NIH), most western populations are magnesium deficient. Magnesium deficiency can lead to a number of health problems such as high blood pressure, heart disease, stroke, osteoporosis and arthritis, to name only a few. Sulphate is also essential for many biological processes and at the same time sulfation is a major pathway in detoxifying drugs and environmental contaminants. According to the School of Biosciences of the University of Birmingham, sulphate is not easily absorbed across the gut wall. The recommended treatment up to now for absorbing these nutrients was bathing in Epsom salts, a procedure that calls for a considerable amount of time, water and electrical energy.  
MgSO4 Ltd (UK) has developed and patented MgSpa, a new revolutionary alternative to electrical showers, which enables the user to quickly and effectively absorb the necessary Magnesium and Sulphate through the skin, while at the same time ensuring huge savings in water (97% less) and energy (80% less). The MgSpa makes the Epsom salt treatment an easy low cost everyday habit, like taking a shower.
The concept behind the product is to make use not only of the therapeutic properties of the salts, but also of their cleaning ability. So far, the use of soaps made water recirculation in showers impossible and the showers’ water and energy consumption significant. The innovative product uses Magnesium as a cleaning agent and recirculates and reheats shower water to create an invigorating shower experience with minimum environmental impact.
The Phase 1 project will be focused on establishing a complete supply chain, a sound business model and commercialization strategy and planning all activities for deploying a large scale pilot supported by a large hotel/spa chain. The partner SME Caleidos (Italy) will support the industrialization and marketing plan.
REGIONal Strategies 4 FOOD 4.0 Revolution

Data has become a key asset for the food industry which is leading to innovations in technology and the development of new tools and skills.

However, the large volume and diverse nature of food value chains data and actors call for specific integration and management procedures to make the most of new economic opportunities based on information, data and cognitive technologies and promote innovation-driven growth.

With the aim to address this issue, seven regions have decided to join efforts to face new challenges in relation ICTs and data with the overall objective of maximising the innovation potential of all actors of the agri-food value chain.

For this purpose, project partners have developed an exchange of experience approach and work plan which allow them to create synergies and opportunities by identifying good practice implemented in other regions. Partners will work in close cooperation with stakeholders to interconnect regional innovation ecosystems, and bring together the “quadruple helix” of actors involved at different stages in the food value chain. Best practices for each region will be integrated in their action plans in order to improve the targeted policy instruments governance or to implement projects that will contribute to achieving the above-mentioned goal. 

Main project outputs and results will be: 

- Seven action plans to improve policy instruments selected by project partners according to their relevance in terms of better exploiting ICT’s potential and deliver innovation to food industry and hence, smart progress and growth. 
- Support capacity-building at all levels, that is, staff, organisational and regional but also beyond the partnership considering most project partners are members of the S3P Agri-food on Traceabiliy and Big Data. 
- Reinforcing cooperation between research and business sectors and therefore, to improve the economic exploitation of R&D results.
- Delivering strategic guidelines for new programming period.
METHOD AND GAMING MACHINE FOR PROVIDING KENO-LIKE GAME WITH POKER PAY TABLE

A keno game in which 20 poker cards, each card representing one rank and suit of the four possible royals, are arranged in two columns consisting of 10 rows. 20 balls are displayed in conjunction with the 20 cards in which one card and one ball is declared one of 20 positions. If any of the players winning numbers (balls) land in line or position with one of the 20 cards, that card becomes a live feature. A payout is awarded to a player based on a poker hand according to a poker pay table.
Uncertainty Analysis of a Coupled Hydrological-plant Growth Model for Grassland under Elevated CO2

The continuous increase in atmospheric carbon dioxide (CO 2 ) contributes to changes in plant evapotranspiration and terrestrial water budgets in two ways. Firstly, elevated CO 2 can result in a water saving effect, since increasing CO 2 reduces stomatal opening and therefore decreases transpiration. Secondly, CO 2 fertilization increases biomass accumulation and leaf area at plant canopy level, likely increasing transpiration 1 . Vegetation and hydrological models can be used to investigate the CO 2 response and the bidirectional effects outlined above, including their relative contribution to the changes in the water cycle. However, the intrinsic plant-soil interaction and the uncertainty related to model parameterization have rarely been considered. Hence, we coupled a detailed plant growth and soil hydrological model by using the generic model frameworks Plant growth Modelling Framework (PMF) 2 and Catchment Modelling Framework (CMF) 3 . Up to date response mechanisms have been implemented in PMF to simulate the various ways of how plant physiology is influenced by elevated CO 2 . Both models interact by using the Python computer language. Applying the coupled PMF-CMF model we investigate the effects of elevated CO 2 in a number of plant physiological and environmental variables such as biomass, leaf area index and soil moisture using field data of a long-term Free Air Carbon Enrichment (FACE) experiment in Giessen, Germany. In this experiment, various grassland varieties (herbs, legumes, grass) grow under elevated (+20%) and ambient CO 2 since 1997. A Monte Carlo based uncertainty analysis (GLUE) is conducted to investigate the coupled PMF-CMF parameter space. The focus will be on the identification of parameters for plant and soil, which are the drivers for the CO 2 response of the terrestrial water balance. We will present first results of the simulation of biomass accumulation and transpiration under ambient and elevated CO 2 concentrations.
Chromium and nickel in Pteridium aquilinum from environments with various levels of these metals

Pteridium aquilinum is a ubiquitous species considered to be one of the plants most resistant to metals. This fern meets the demands for a good bioindicator to improve environmental control. Therefore, it was of interest to survey the accumulation of Cr and Ni in the rhizome and fronds of this species collected in Lower Silesia (SW Poland) of serpentinite rich in Cr and Ni and granite poor in these metals. Additionally, concentrations of Cd, Co, Cr, Cu, Fe, Mn, Ni, Pb, and Zn were measured in granite and serpentinite parent rocks, soils, and in P. aquilinum (rhizome and fronds). The experiment was carried out with rhizomes of ferns from both types of soils placed in pots supplemented with 50, 100, and 250 mg kg(-1) of Cr or Ni or both elements together. At a concentration of 250 mg kg(-1) of Cr, Ni, or Cr + Ni, fronds (from granite or serpentinite origin) contained significantly higher Cr and Ni concentrations when both metals were supplied together. In the same concentration of 250 mg kg(-1) of Cr, Ni, or Cr + Ni, rhizomes (from granite or serpentinite origin) contained significantly higher Cr and Ni concentrations when both metals were supplied separately. The explanation of metal differences in the joint accumulation of Cr and Ni on the rhizome or frond level needs further investigation. The lack of difference in Cr and Ni concentration in the rhizome and fronds between experimental P. aquilinum collected from granite and serpentinite soils may probably indicate that the phenotypic plasticity of this species is very important in the adaptation to extreme environments.
ARRANGEMENT WITH AT LEAST ONE SIGN SECURED TO AT LEAST ONE POST

In a sign arrangement of the kind comprising : (a) one or several substantially vertical posts (1, 2) and (b) a number of sign elements (3) placed in pairs opposite each other on each side of a plane through the axis or axes of the post or posts (1, 2), the new feature is (I) that each sign element (3) on the side facing the post or posts (1, 2) comprises one or several cutouts (4) generally corresponding to one-half of the cross-sectional shape of the post or posts, and (II) that each pair of sign elements (3) is adapted to be secured against each other and in clamping engagement about the post or posts by clasps (5) extending across said plane. When the various components of the arrangement are suitably constructed, this arrangement makes it possible to place the signs in position without the use of tools, whereas they can only be removed by means of tools and with a knowledge of the construction of the sign arrangement.
BLEND OF STYRENE POLYMERS FOR USE IN FLOOR POLISH COMPOSITIONS

A floor polish composition having excellent resistance to plasticizer migration contains water, a mixture of a styrene copolymer (styrene and acrylic or methacrylic acid) and a styrene multi-polymer (styrene, acrylic acid, an ester of acrylic acid and acrylonitrile) and suitable waxes, alkali soluble resins and surfactants.
Effects of Anthropogenic Particles on the Chemical and Geophysical Properties of Urban Soils, Detroit, Michigan

A study was undertaken to assess the effects of anthropogenic particles on the pH, electrical conductivity (EC), and magnetic susceptibility (MS) of anthropogenic soils in Detroit, Michigan. The results showed that ^Au horizons of anthropogenic soils at residential demolition, industrial, and fly ash–impacted sites were distinguishable from A horizons of native soils (background level). Anthropogenic soils were higher by 1 pH unit or more, had an EC three to four times background level, and were characterized by an elevated MS that was up to 20 times background. Anthropogenic soils at residential demolition sites had a uniquely high EC signature, whereas those at industrial sites were distinguished by anomalously high MS. Fly ash–impacted soils differed from native soils but were similar to other anthropogenic soils. Analyses of reference artifacts suggest that the elevated pH of anthropogenic soils was caused by calcareous building material wastes, whereas elevated EC were the result of both calcareous and ferruginous wastes. Elevated MS were attributable to ferrimagnetic materials such as corroded iron nails, coal ash and cinders, and metalliferous slag. Analyses of “artificial soils” indicated that there were measurable effects on pH, EC, and MS even with low concentrations of anthropogenic microparticles (<5–10 wt %). These results support our hypothesis that urban soils contain anthropogenic particles that differ as a function of former land use. Hence, various types of anthropogenic soils and native soils have unique chemical and geophysical signatures. This suggests that EC and MS surveying methods may be used to remotely sense and map urban soils more effectively than using traditional methods alone.
Adsorption and separation of binary and ternary mixtures of SO<sub>2</sub>, CO<sub>2</sub> and N<sub>2</sub> by ordered carbon nanotube arrays: grand-canonical Monte Carlo simulations

The adsorption and separation behavior of SO2-CO2, SO2-N2 and CO2-N2 binary mixtures in bundles of aligned double-walled carbon nanotubes is investigated using the grand-canonical Monte Carlo (GCMC) method and ideal adsorbed solution theory. Simulations were performed at 303 K with nanotubes of 3 nm inner diameter and various intertube distances. The results showed that the packing with an intertube distance d = 0 has the highest selectivity for SO2-N2 and CO2-N2 binary mixtures. For the SO2-CO2 case, the optimum intertube distance for having the maximum selectivity depends on the applied pressure, so that at p < 0.8 bar d = 0 shows the highest selectivity and at 0.8 bar < p < 2.5 bar, the highest selectivity belongs to d = 0.5 nm. Ideal adsorbed solution theory cannot predict the adsorption of the binary systems containing SO2, especially when d = 0. As the intertube distance is increased, the ideal adsorbed solution theory based predictions become closer to those of GCMC simulations. Only in the case of CO2-N2, ideal adsorbed solution theory is everywhere in good agreement with simulations. In a ternary mixture of all three gases, the behavior of SO2 and CO2 remains similar to that in a SO2-CO2 binary mixture because of the weak interaction between N2 molecules and CNTs.
NIM SRL UNIPERSONALE

SOLICITUD DE FACILITACIÓN MENCIONADA EN EL ANUNCIO PÚBLICO DE SUBVENCIONES DE PEQUEÑAS ENTIDADES A PYME SUSPENDIDAS O CON UNA DISMINUCIÓN GRAVE DEL VOLUMEN DE NEGOCIOS