SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Inventor networks in emerging key technologies: information technology vs. semiconductors

This paper analyzes the development of the German knowledge base measured by co-classifications of patents by German inventors and relate this technological development to changes in the structure of the underlying inventor networks. The central hypothesis states that technologies that become more central to the knowledge base are also characterized by a higher connectedness of the inventor network. The theoretical considerations are exemplified in a comparative study of two patenting fields—information technology and semiconductors. It turns out that information technology shows the highest increases in patents, but only a moderate move towards the center of the knowledge base. By contrast, semiconductors develops towards a key technology, despite a moderate increase in the number of patents. The dynamic analysis of inventor networks in both fields shows an increasing connectedness and the emergence of a large component in semiconductors, but not in information technology, which is in line with the expectations.
Clamp for continuous welding of short tubes - has clamping jaws and internal mandrel with centering pins spring loaded

The clamping head is used for holding a given length of a rolled and formed sheet metal tube while its edges are joined by welding to form a tube. The clamping head has a mandrel with centering pins for supporting and centering the tube while it is held by jaws and welded. The mandrel has a copper pad which is placed directly under the welding head. The mandrel has side flats which facilitate ejection of the completed tube. The spring loaded centering pin and fixed pin engage with end slots in the tube which are diametrically opposite the joint. Swivelling jaws have spring mounted strips and these exert centering force on the tube length. Tubes are readily inserted and ejected from this clamping head.
NOVEL CHIMERIC PLASMINOGEN ACTIVATORS AND THEIR PHARMACEUTICAL USE

The present invention relates to recombinant chimeric proteins comprising a surfactant protein precursor N-terminally fused to a plasminogen activator or comprising a mature surfactant protein N-terminally or C-terminally fused to a plasminogen activator. The invention is also directed to the corresponding nucleic acid molecules encoding such fusion proteins as well as to a method for their production. The invention further refers to a pharmaceutical composition comprising such a fusion protein and to pharmacological uses of an inventive fusion protein for the prevention and/or treatment of inflammatory and interstitial lung diseases.
The most advanced micromotors in the world

Micromotors are ubiquitous, used in your electric toothbrush, in your dentist’s drill and in modern industrial robots. The most important component that determines motor performance, functionality and longevity, is the copper winding, which dictates how much power a motor can generate for a given current. The way these copper windings are produced has not changed much over the last 40 years: they are either wound by hand for prototyping or for small production runs, or they are produced by expensive machines that are complex to operate, inflexible and viable only for large production runs. 
Mirmex is transforming the way micromotor windings are produced: instead of winding copper wire by hand, Mirmex prints them on PCB’s before rolling them with high precision. This approach to producing windings has many user benefits: motors are easier and less costly to prototype, they are more flexible in design terms, more durable, lighter, become hot less quickly, feature higher torque and greater dynamics - and all at a lower cost than the incumbent technologies. 
The go-to-market strategy will focus initially on the surgical/dental power tools segments because they care more about performance, weight and other value-added features than about price. Mirmex will then address the industrial/automotive sector and begin producing motors, in addition to windings. Demand is already strong: Mirmex has received purchase orders worth €80k for small quantities of prototype products and 8 LOIs. 
In order to fully exploit the very high commercial potential of our innovation, Mirmex needs to demonstrate that (i) it is able to manufacture windings of exceptional quality in commercial volume, (ii) the products meet the stringent requirements for autoclavability from medical customers and (iii) our winding design software tool can interface with a higher number of materials and motor architectures. Mirmex then expects rapid scale-up, targeting revenues of €31.5m and EBITDA of €11.7m by 2024
Specialization in the knowledge economy

Human beings accumulate two types of capital: human –knowing what- and social –knowing who. In this project, I aim to understand how these types of capital affect the organization of firms and economies, with the goal of providing insights into the determinants of productivity and governance. This multidisciplinary project, composed of three sections, will provide insights to businesses and policy makers to enhance growth in the knowledge economy. In the first section, I use data from the US lobbying industry to deepen our understanding of social capital and its dynamics. Using the relational contracting literature as a theoretical framework, I will quantify the importance of lobbyist-client relationships by exploiting exogenous switches to the lobbyist’s social capital. The section aims to inform the policy debate on how to reduce political corruption and improve the quality of regulation in advocacy services. In the second section, I study the effects of human capital differences emerging from specialization across fields. I present a theoretical model where employees might face tasks they cannot solve. The firm has to optimally design a rule to help them choose between passing these problems to managers in their division or to employees in other divisions. I test the theory using Mexican consulting firms’ data, which contain detailed information on frequency and types of interactions for all workers. The section aims to guide firms on how structure their divisions to increase productivity and operational efficiency. In a similar vein, the third section explores the effects of specialization across clients. Using data from a Colombian security services firm, I will use client-fixed effects estimations to study whether client-specific skills are more important than other skills for the performance of security guards. The goal is to provide guidance to increase the efficiency of the work load as well as the optimal allocation from workers to clients.
A hierarchical approach for the design improvements of an Organocat biorefinery

Lignocellulosic biomass has emerged as a potentially attractive renewable energy source. Processing technologies of such biomass, particularly its primary separation, still lack economic justification due to intense energy requirements. Establishing an economically viable and energy efficient biorefinery scheme is a significant challenge. In this work, a systematic approach is proposed for improving basic/existing biorefinery designs. This approach is based on enhancing the efficiency of mass and energy utilization through the use of a hierarchical design approach that involves mass and energy integration. The proposed procedure is applied to a novel biorefinery called Organocat to minimize its energy and mass consumption and total annualized cost. An improved heat exchanger network with minimum energy consumption of 4.5 MJ/kgdry biomass is designed. An optimal recycle network with zero fresh water usage and minimum waste discharge is also constructed, making the process more competitive and economically attractive.
The use of blood products in the Intensive Therapy Unit

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 Aims – This audit was undertaken to establish whether use of packed red cell (PRC) transfusions in the Intensive Therapy Unit (ITU) was in line with best clinical evidence. It aimed to help optimise the use of blood transfusions, thereby improving patient safety and reducing costs. Methods – This retrospective audit examined blood transfusions administered in the ITU over a six month period. The indication for transfusion was identified from the requesting database or medical notes in order to assess whether the transfusion was appropriate. The data was used to establish the number of transfusions administered inappropriately, average number of units administered per session and average haemoglobin at which PRC were transfused. Results – 131 units of PRC were transfused in ITU during the 6 month period. 25 units (19.1%) administered in 13 transfusion sessions were deemed ‘inappropriate.’ Excluding cases of acute bleeding, 2 units of PRC were transfused in 38 (79.2%) sessions, whilst single units were transfused in 10 (20.8%) sessions. The mean haemoglobin at which patients were transfused was: 7.4g/dL (transfusions within guidelines); 6.7g/dL (within guidelines but excluding acute bleeding and cardiac history); 7.9g/dL (outside guidelines but clinically justified); 7.7g/dL (not justified). Inappropriate transfusions exposed a minimum of 6 patients to unnecessary risk, and were associated with a cost of £4245.24. Conclusions – 77% PRC transfusions were given appropriately; a relatively conservative transfusion strategy was evident, however, there was still a tendency to transfuse multiple units. Increasing awareness of the available evidence may help to reduce the number of inappropriate transfusions and consequently reduce unnecessary risk to patients and costs of treatment.
Fully automated robotic system for all process steps of the hairtransplantation surgery procedures (fue-robotic system)

FULLY AUTOMATED ROBOTIC SYSTEM for ALL PROCESS STEPS of the HAIR TRANSPLANTATION SURGERY PROCEDURES (FUE-Robotic System)

We introduce a groundbreaking innovation which is a patented Robotic System into Hair Treatment Field.

Hair transplantation is used to treat hair loss, a condition that affects more than 50 million men and 30 million women in the world. The total market size for hair transplantation surgery has increased 28% since 2012, or from 1.9 billion EURO (€) in 2012 to 2.5 billion EURO (€) in 2015*. At almost 1.050.000 Hair Transplantation Procedures are performed annually worldwide*. It is a fantastic opportunity to reach an Untapped Market.

The submitted proposal relates to a method and apparatus for hair transplantation and in particular a method and apparatus for FUE Method Hair Transplantation which utilizes SCS (Spherical Coordinate System) Mechanism, Gripper and 3D Data Processing Software.

Our Patented FUE Robotics System is the First and Only Robotic Hair Transplant System to safely introduce completing the whole Process Steps of the FUE Hair Restoration Surgery Procedure without any Human Error Factor.

Furthermore, The FUE Robotics System can reduce up to 85-90 % of surgery time period when compared to manual FUE techniques and currently being developed other Robotic Systems in the market in the USA. It provides The Best Quality - Quantity - Price Ratio of all available hair transplantation methods. Other hair transplantation techniques cannot offer these highly sophisticated technological advancements.

*Source; The International Society of Hair Restoration Surgery (ISHRS), 2015 Practice Census.

This Proposal was submitted for another Work Programme Topic on the previous Cut-Off Day and ESR Total Score: 13,78 but it was not provided because of the Limited Budget in SMEInst-06-2016-2017: Accelerating Market Introduction of ICT Solutions for Health, Well-Being and Ageing Well. Seal of Excellence: Annex Page:20 .
A coaxial HOM coupler for a superconducting RF cavity and its low-power measurement results

A resonant buildup of beam-induced fields in a superconducting radio frequency (RF) cavity may make a beam unstable or a superconducting RF cavity quench. Higher-order mode (HOM) couplers are used for damping higher-order modes to avoid such a resonant buildup. A coaxial HOM coupler based on the TTF (TESLA Test Facility) HOM coupler has been designed for the superconducting RF cavities at the Proton Engineering Frontier Project (PEFP) in order to overcome notch frequency shift and feed-through tip melting issues. In order to confirm the HOM coupler design and finalize its structural dimensions, two prototype HOM couplers have been fabricated and tested. Low-power testing and measurement of the HOM couplers has shown that the HOM coupler has good filter properties and can fully meet the damping requirements of the PEFP low-beta superconducting RF linac.
Rehabilitation hub: the world’s first digital recovery therapy solution

Over 100M people in Europe suffer from chronic musculoskeletal disorders (MSD) such as rheumatoid arthritis, neck, lumbar and shoulder pain. However, the standard rehabilitation protocol is expensive and ineffective – our work in Phase 1 confirmed that the majority of rehabilitation programmes are not followed consistently and a staggering 80% of patients abandon their treatment prematurely, increasing likelihood of reinjure. 
To solve this problem, Bio-Sensing Solutions has dedicated the past 3 years to developing our DyCare® ReHub tele-rehabilitation solution that offers support for diagnosis and delivers effective, personalised therapy for MSD sufferers. With our proprietary wearable sensor and intelligent algorithms, physiotherapists will, for the first time, be able to create a rehabilitation programme based on objective measurements of a patient’s muscle strength and joint movement, whilst monitoring their progress remotely, adjusting the exercises on the fly if needed.
For the patient, ReHub guides them through each custom-tailored home exercise and empowers them with real-time performance biofeedback. And, with an innovative B2B2C business model, the Physician, Physiotherapist and Patient can stay connected via an easy-to-use online platform. 
We have validated our first prototype in 3 leading health centres, placing our innovation at TRL 7. ReHub has shown to reduce patient recovery time by 40%, boost rehab completion to 90% and increase health centre productivity by 60%. We aim to become leaders in the 4 B€ MSD rehabilitation market in Europe. We are requesting SME Instrument Phase 2 funding to optimise ReHub core algorithms, industrialise our hardware components and validate performance in 2 large-scale clinical studies. By 2022, we expect to sell a total of 1,239 ReHub licenses and reach 165k patients, growing our team to 26 skilled professionals and company revenues to 13.8 M€.
THE WORKSHOP OF CIFELLI NICOLINO

OPERATING COMPANY SINCE 2016 CARRYING OUT MECHATRONIC SECTION SELF-REPAIR ACTIVITIES CONDUCTED BY THE OWNER CIFELLI NICOLINO, FOR MANY YEARS EMPLOYED IN THE SELF-REPAIR SECTOR, BOTH AS OWNER PREVIOUSLY AND AS AN EMPLOYEE. SELF REPAIRS NICOLA OFFERS COMPUTERISED DIAGNOSIS, RECHARGING OF AIR CONDITIONING SYSTEMS FOR MOTOR VEHICLES, MECHANICAL REPAIRS, REPLACEMENT BRAKE PADS, COUPONS, TESTS, INTERVENTIONS ON ELECTRICAL AND ELECTRONIC SYSTEM, BALANCING WHEELS AND IS AIMED AT A VARIED MARKET, WITH CUSTOMERS LOCATED THROUGHOUT THE PROVINCE OF IMPERIA. TODAY THE COMPANY IS HEADQUARTERED IN THE MUNICIPALITY OF TAGGIA, IN A VERY LARGE SPACE EQUIPPED WITH LIFT BRIDGES, TYRE DISMANTLING, BALANCING MACHINE, SELF-DIAGNOSIS, CLIMATE CHARGING STATION, TROLLEYS, SHOCK ABSORBERS, GRINDER, COMPRESSORS AND SMALL TOOLING OF VARIOUS KINDS. FOLLOWING THE SUBSTANTIAL TRANSFER OF THE HEADQUARTERS, THE COMPANY REQUESTED AND OBTAINED FROM HONDA L’EXCLUSIVITA’
Re- Os Isotopic Dating of Molybdenites from the Shazigou W- Mo polymetallic Deposit,Inner Mongolia and its Geological Implications

The Shazigou W- Mo polymetallic deposit of Inner Mongolia is located in the southwest of the Xilamulun molybdenum metallogenic belt in the northern margin of the North China Craton. The molybdenites occurring as quartz-molybdenite-pyrite assemblages are usually vein-like,existing in the wallrock fractures. In order to determine the metallogenic age of this W- Mo deposit,we have made measurements to Re- Os isotope on 5 molybdnite samples collected from the deposit,yielding the model ages between( 241. 2 ± 3. 4) Ma and( 245. 2 ± 4. 3) Ma,with an average value of 243. 8 ± 1. 6Ma. It indicates that the mineralization in the Shazigou W- Mo multi-metal deposit occurred in the early Triassic. The Re contents of molybdenites in Shazigou vary from 1. 231μg / g to 1. 704μg / g,which can be used as an important indicator on the source of ore-forming material. It is likely that the Mo ore-forming material in the deposit was derived from the upper crust. Comparing with other Mo or Mo-bearing deposits in the regional molybdenum metallogenic belt,it is inferred that the formation of the Shazigou W- Mo deposit is associated with the collision of the North China and Siberria Plates after the closure of the Paleo-Asian Ocean. The ore-forming age of this deposit provides new evidence for the tectonic magmatic mineralization in the northern margin of the North China Plate in the of early Triassic,which will help expand the scope of regional prospecting.
Dna-Based modular nanorobotics

Robotic systems essentially comprise sensors and actuators connected to and coordinated by an information-processing unit. These principles apply to the human scale robotic systems that currently transform the way we work and live. With DNA-Based Modular Robotics (DNA-Robotics) we will take the first steps to scale advanced robotic behavior to the molecular scale for future medical and technological applications. DNA-Robotics brings together the leading research groups in DNA nanotechnology in Europe to collectively develop an integrated and modular robotic platform and demonstrate applications of the novel technology. DNA-based construction is a natural modular platform, which via the programmability of sequence design and self-assembly allows different structural and functional motifs to be flexibly combined. DNA modules will be developed with a range of novel functions for sensing, actuation and intra-system communication and computing, implementing all of the typical components required for a robotic system at the molecular level. Our overall goal is the creation of the first “industry standard” for modular robotics by the establishment of a modular “plug-and-play” platform that allows the construction of custom-made nanorobots for advanced applications in research and industry. The ESRs will be trained in and develop functional modules that in close collaboration among the ESRs and Partners will be assembled to advanced molecular robots. The highly interdisciplinary research and training program will exploit the synergy between the different competences of the Partners. The innovative and applied focus is supported by the involvement of the company ATDBio as Beneficiary and five companies as Partner Organization that will also provide complementary skills training and intersectoral exposure of the ESRs. This proposal takes the first steps for future application of nanoscale robots in research and industry and will train future generations of researchers in this field.
Heterogeneity of melanomas: from the mountains to the sea - sea level, sun exposure and pollution in the development of cutaneous neoplasia

Cutaneous melanoma has become an increasingly common tumor in most developed countries as a consequence of greater exposure of pale Caucasian skin to natural ultraviolet (UV) radiation. The aim of the project MEMS is to strengthen the partnership among research institutes in the programme area favouring the interchange of technical as well as scientific knowledge on cutaneous melanomas. Through the partnership of health and research institutions in Italy and Austria, the project will investigate if environmental variables, such as the altitude of residence, UV and/or pollutants exposure could contribute to the development of specific types of cutaneous melanomas and could promote its progression. _x000D_
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Innovation in this project will refer to association of local heterogeneity to clinical, microscopic and molecular heterogeneities in cutaneous melanoma. The trans-border area of our partnership is heterogeneous: the seaside (Trieste), Northern and Southern Alps (Tyrol and South Tyrol), and the valleys (Aviano). That area is mostly populated by pale-skin inhabitants, with higher incidence of cutaneous melanomas. In that population we are going to characterize melanoma heterogeneity on the clinical and molecular level in order to associate those variables to environmental ones to investigate their relationship with the development of the disease.
The outstanding challenge in solid mechanics: engineering structures subjected to extreme loading conditions

In this project we aim to train early-stage researchers in what is referred to as an outstanding challenge in solid mechanics: developing novel solutions for the analysis and design of aerospace and defense structures subjected to extreme loading conditions. Structural elements used in these sectors are frequently subjected to a large variety of unusually severe thermo-mechanical solicitations. One easily realizes that this type of structures (e.g. components for satellites) has to be designed to sustain extreme temperatures, which may vary hundred degrees in short periods of time, and extreme mechanical loadings like hypervelocity impacts. New specific structural solutions are constantly developed to fulfill such requirements, which place these industrial sectors in the forefront of the technological innovation. Hereby, aerospace and defense industries constitute the natural meeting point between academia and entrepreneurial fabric. A deep understanding of the response of structures under the aforementioned sharp solicitations is mandatory for design purposes. Unfortunately, not even today is easy to find researchers in the labour market with such specific (and complicated) understanding. Aerospace and defence industries require highly-qualified technical staff capable of developing research and innovation within the framework of structural mechanics. This is the precise context where our proposal lies. We intend to form a consortium composed of 3 academic beneficiaries and 2 industrial beneficiaries which aims at developing specific training for early-stage researchers within the field of aerospace and defense structures subjected to severe thermo-mechanical loads. The leitmotif of this ITN is to train creative and innovative researchers ready to face structural-engineering challenges which arise in the vanguard of technological innovation.