SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Subsurface fluid injection and induced seismicity in southeast Saskatchewan

Abstract In order to mitigate CO2 emissions while continuing to use fossil fuels as an energy source, CO2 emissions from large point sources such as power stations can be captured and stored in suitable subsurface sedimentary formations. However, concerns have been raised that the injection of pressurized CO2 may alter the subsurface stress state, leading to the re-activation of faults and generating induced seismic activity. Southeast Saskatchewan has seen extensive oil and gas activity since the 1950s. This activity includes, in recent years, a boom in shale oil production entailing hydraulic fracturing. It is also home to two world-leading CCS projects, the Weyburn-Midale CO2 Monitoring and Storage Project, and the Boundary Dam/Aquistore Project. The aim of this paper is to assess whether any of the conventional oilfield operations, shale oil activity or CCS has caused induced seismicity in southeast Saskatchewan. We find that the region has a very low rate of natural seismicity, and that there is no evidence to suggest that any kind of oilfield activity has caused induced events. However, seismicity has been associated with potash mining activities in the region. It is not clear whether the potash mining-induced events are triggered by subsidence above the mined zones, or by re-injection of waste brines. It is of interest to compare the situation in southeast Saskatchewan with other areas that have seen substantial increases in the amount of injection-induced seismic activity. It is notable that in many areas that have seen injection-induced seismicity, fluid injection is into basal aquifers that are hydraulically connected to the crystalline Precambrian basement. In contrast, most oilfield activities in southeast Saskatchewan are in Carboniferous formations, while the only units to have experienced a net volume increase are of Cretaceous age. It is tentatively suggested that the lack of induced seismic activity is due to the fact that injection is hydraulically isolated from the basement rocks, although it is also possible that stress conditions in the region are less conducive to induced seismicity.
Quantitative assessment of the diagnostic role of human telomerase activity from pancreatic juice in pancreatic cancer

Many studies have shown that human telomerase activity could play potential role as a diagnostic biomarker of pancreatic cancer (PaC). The aim of this meta-analysis is to summarize the clinical value of human telomerase activity in the diagnosis of PaC. Eligible studies from PubMed, Embase, the Cochrane Library, Web of Science, Ovid, Sci Verse, Science Direct, Scopus, BioMed Central, Biosis previews, Chinese Biomedical Literature Database (CBM), Chinese National Knowledge Infrastructure (CNKI), Technology of Chongqing (VIP), and Wan Fang databases were searched concerning the diagnostic value of human telomerase activity in PaC without language restriction. The quality of each study was scored with the Quality Assessment of Diagnostic Accuracy Studies (QUADAS). Sensitivity, specificity, positive and negative likelihood ratios (PLR and NLR, respectively), and diagnostic odds ratio (DOR) for human telomerase activity in the diagnosis of PaC were pooled. Summary receiver operating characteristic (SROC) curve analysis and the area under the curve (AUC) were used to estimate the overall test performance. Evidence of heterogeneity was evaluated using the Chi-square and I (2) test. Meta-Disc 1.4 and Stata 12.0 software were used to analyze the data. Nine studies with a total 186 PaC patients and 132 control individuals were included in this meta-analysis. All of the included studies are of high quality (QUADAS score ≥10). The summary estimate was 0.83 (95 % confidence interval (CI), 95 % CI = 0.77-0.88) for sensitivity and 0.72 (95 % CI = 0.64-0.79) for specificity. The positive likelihood (PLR), negative likelihood (NLR), and diagnostic odds (DOR) ratios were 3 (95 % CI = 1.67-5.41), 0.25 (95 % CI = 0.13-0.46), and 3 (95 % CI = 4.91-43.23), respectively. The area under the summary ROC curve (AUC) and Q* index for the diagnosis of PaC were 0.88 and 0.81, respectively. Our study demonstrates that telomerase could be a useful tumor marker for PaC diagnosis. Although more studies are needed to highlight the theoretical strengths, these results will provide theoretical basis for bringing telomerase activity detection into PaC screening plan.
voci delle intersezioni: Postcolonialismo e femminismo

All’inizio degli anni ’80 nell’Università di Delhi, un gruppo di studiosi si riunisce per riflettere sulle relazioni tra Occidente ed Oriente. Il collettivo nato dallo storico Ranajit Guha, prende il nome di Subaltern Studies, richiamando le teorie gramsciane sulla subalternità. L’analisi dei rapporti di dominio e soggezione tra coloni e colonizzati è centrale nello sviluppo di queste nuove teorie postcoloniali. I protagonisti di questo fervente dibattito non circoscrivono il postcolonialismo dentro precisi confini geografici: la condizione postcoloniale è principalmente ideologica, poiché nasce come prodotto delle relazioni e dei processi storici di colonizzazione. All’interno dei Subaltern Studies, la studiosa Gayatry Chakravorty Spivak (1985) si interroga sull’assenza del soggetto femminile nel discorso dei suoi colleghi, ponendo una domanda fondamentale per la teoria postcoloniale e per la teoria femminista: “La subalterna può parlare?” (1988). La donna appare un soggetto ventriloquizzato e costantemente rappresentato e definito dallo sguardo dell’altro. Spivak centra l’attenzione sul bisogno di autodeterminazione del soggetto femminile. Alla voce della filosofa indiana fanno eco le femministe chicanas e afroamericane, che dagli Stati Uniti reclamano un femminismo che tenga conto di tutte le subalternità che agiscono sul corpo femminile, prima fra tutte la razza. La declinazione dell’intersezione tra sesso, razza e classe assume un ruolo fondamentale sia nella teoria postcoloniale che in quella femminista. Nel presente lavoro si analizzano le principali rivendicazioni e le strategie di resistenza usate dalle voci delle subalterne, che marcano alcuni momenti di incontro/confronto tra femminismo e postcolonialismo.
Violence and its control in early modern venice, 1500-1797

Violence is the result of complex interactions between cultural, social, economic, political and environmental factors and is subject to changes that reflect on-going transformations within society. Investigating its perception and understanding the boundaries between tolerated, sanctioned, and unacknowledged violence allows to examine inter-personal relationships within a community and the shared value systems within it. The management of violence is then a direct consequence of specific political factors, which are expressed on the judicial level. Studying violence during the early modern age is of fundamental importance to understand, for example, the role and weight of the state within society.
This research project will study the rate of violence in the Venetian urban environment during the early modern age and the efforts made by the Republic to reduce it. The project will pay particular attention to political violence among members of families belonging to the Venetian ruling class, to verify whether the Venetian context was an exception in the European context. The project will examine the transformations that the Venetian judicial bodies underwent to demonstrate what impact they had on violence, either by increasing or effectively containing it. In addition to the judicial system, the project will also examine the policing measure and the expansion of the surveillance network as a form of control of the urban territory. The results achieved will be compared with the rates of political violence, caused by factionalism, in the Italian mainland under Venetian rule.  Finally, the project will verify how the Republic tried to put a brake on another main source of violence, the one linked to border banditry. Venice repeatedly negotiated extradition treaties with its neighbouring states in order to deny any space of immunity to outlaws, but the execution of these agreements had little success.
Incorporating Hierarchical Dirichlet Process into Tag Topic Model

The Latent Dirichlet Allocation (LDA) is a parametric approach and the number of topics must be predefined. So it is natural to try to capture uncertainty regarding the number of topics. This paper proposes a Tag Hierarchical Dirichlet Process (THDP) that automatically infers the number of topics while also leveraging the tag information associated with each document. In this model, we assume that an author is clear in his mind that the content will contains which aspects and for each aspect he will choose a tag to describe it, and then we consider problems involving groups of tag, where each tag within a group is a draw from a mixture model and it is desirable to share topic between groups. In this setting it is natural to consider Hierarchical Dirichlet Process, Where the well-known clustering property of the Dirichlet process provides a nonparametric prior for the number of topic within each tag. Experimental results on corpora demonstrate superior performance over the THDP model.
Risk assessment and sustainable protection of Cultural Heritage in changing environment

Disasters and catastrophes pose risks not only to the conservation of the cultural heritage assets with its cultural, historic and artistic values, but also to the safety of visitors, staff and local communities. Additionally they cause undoubtedly negative consequences for the local economies due to the loss of tourism revenues, and for the livelihoods of local people who are dependent on it. ProteCHt2save outcomes will strongly contribute to improve capacities of the public and private sectors to mitigate the impacts of climate change and natural hazards on cultural heritage sites, structures and artefacts. The project focuses primarily on the development of feasible and tailored solutions for building resilience of cultural heritage to floods and events of heavy rain by applying an integrated and transnational comprehensive approach with the aim of implementing regional and local strategies on preparedness measures and evacuation plans in emergency. ProteCHt2save will deliver ICT solutions (inventory and maps) and tools (decision support tool, best practices manual, handbook on transnational rescue procedures) for risk management and protection of cultural heritage in Central Europe. Pilot actions selected on the base of risk prone areas and cultural heritage vulnerabilities will be used to implement and assess the developed ProteCHt2save strategies, and to improve the existing disaster risk management plans and policies in the CE Municipalities. Input to adaptation policies of government organisations thereby promoting improved strategies and plans for the protection of cultural heritage will be ensured as major impact. By the achievement of the planned objectives, ProteCHt2save is expected to proactively target the needs and requirements of stakeholders and policy makers responsible for disaster mitigation and safeguarding of cultural heritage assets and to foster the active involvement of citizens and local communities in the decision making process.
Method for the detection of bacterial species of the genera Anaplasma/Ehrlichia and Bartonella

The present invention, relating to a method for the detection and identification of bacterial species belonging to the genera Anaplasma/Ehrlichia and Bartonella, is a patent of addition to the Spanish patent application with publication number 2.264.642. In addition to this method, the invention also provides the primers and probes required for its application.
Equilibrium Vertical Integration with Complementary Input Markets

Abstract We provide a model to investigate vertical integration decisions. This model assumes that local downstream manufacturers require two inputs to make their final products. One input is produced by a supplier shared by both manufacturers; another is produced by an exclusive supplier for each manufacturer. We show that vertical integration of each downstream firm with its exclusive supplier enhances the input demand for the common supplier, leading to an increase in the common supplier's input price due to the elimination of the double marginalization. Moreover, downstream firms that require a smaller quantity of inputs from the common supplier, for instance, those with efficient production technology or smaller downstream demand, are more likely to vertically integrate because vertical integration yields a smaller increase in input price. Thus, the cause of firm-size heterogeneity is important to consider when investigating the relationship between firm size and the tendency to vertically integrate.
High contrast demonstrations with the vortex coronagraph

The optical vortex coronagraph (OVC) has great potential both for carrying out high-contrast exoplanet searches around nearby stars, and for reducing the size of the space telescopes needed for exoplanet imaging and spectral characterization missions. This is because using a coronagraphic mask to modify the phase of a focal-plane stellar point spread function, instead of its intensity, leaves transmissions high even at small angular offsets from the center of the mask. Here we discuss recent progress in demonstrating the capabilities of the OVC, including the production of vector vortex phase masks, and recent contrast measurements obtained for optical vortex masks in the Jet Propulsion Laboratory's High Contrast Imaging Testbed (HCIT). Specifically, monochromatic contrasts below 10-9 have recently been demonstrated across wavefront-corrected “dark hole” regions extending from 2–7 λ/D from a laboratory simulated “stellar” point source, where λ is the wavelength, and D is the aperture diameter. Initial broadband (10% bandwidth) contrasts are not far behind, at approximately the 10−8 level. Further work is aimed at deepening and broadening wideband contrasts in the dark hole. It is anticipated that further development of broadband vortex phase masks should be able to provide the capabilities required by future space-based coronagraphic instruments aimed at exoplanet imaging and spectroscopy.
Communication about social status

Dominance hierarchies are ubiquitous in social species and serve to organize social systems. Social and sexual status is communicated directly among animals via sensory systems evolved in the particular species. Such signals may be chemical, visual, auditory, postural or a combination of signals. In most species, status is initially established through physical conflict between individuals that leads to ritualized conflict or threats, reducing possibly dangerous results of fighting. Many of the status signals contain other information, as in some bird species that communicate both the size of their group and their individual rank vocally. Recent studies have shown that scent signaling among hyenas of east Africa is unique, being produced by fermentative, odor producing bacteria residing in the scent glands.
Working capital subsidy for the Food and INDUSTRIAL STORE BARBAR

The project concerns support to the company to provide liquidity and to support its day-to-day operations in view of the financial difficulties that have occurred in the company as a result of the COVID-19 outbreak. Financial aid under scheme SA.57015.
Regions for ITS solutions Network

RITS-Net responds to a urgent need to foster sustainability of regional transport policies via the use of Transport Telematics or Intelligent Transport Systems (usually referred to as ITS) solutions at regional level. The recent adoption of the EC Action plan for urban mobility, the ITS Action plan , the EC Directive (2010/40/EU) for the deployment of Intelligent Transport Systems in the field of road transport, and the recently issued With Paper (COM(2011) 144 final) puts more and more emphasis on the use of ITS as a management tool of transport policies. While local ITS implementations already exist in advanced cities, these applications can be very inhomogeneous and generally not interoperable when transport activities spread out the administrative urban boundaries. 
Regions, by integrating the ITS component in a comprehensive regional mobility planning  can improve their transport policies enhancing on one hand their role of coordinators of local actions,
and on the other assuring harmonization of local ITS applications with the ITS Country plans as required by the ITS Directive. 
RITS-Net final objective is to help Regions developing individual ITS regional plans to be integrated in each overall mobility master plan and provide a common methodology to be further replicated.
The partners, composed of Regione Marche (LP); South Dublin County Council; ANATOLIKI SA-Regional Energy Agency of Central Macedonia; Vidzeme Planning Region; Development Centre Litija; Evroregion Pleven – Olt; AustriaTech - Federal Agency for Technological Measures, Autoridad Territorial del Transporte de Gipuzkoa and BIOKOM Pécs City Management, will exchange their mobility policies and practices and the use they make of ITS applications to meet mobility challenges. Via a balanced mix of interregional information, training and exchange of practices sessions together with a series of  7 thematic workshops, partner regions will investigate further the full potential
of ITS solutions in the process of planning and implementing their strategies, covering both technical and non-technical aspects. In this context, cross-matching will be made between partners presenting good practices and regions willing ‘to import’ them. This will be reinforced by the collection of the best ITS solutions in use by non-partner regions, gathered in a digital Tool-box. As the ITS planning requires not only technical knowledge, but mostly organisational capacities, partners will proceed at European and local level in parallel, building the necessary knowledge about ITS solutions from European experiences, while progressively involving local stakeholders in the definition of their ITS visions.
At the end, the partners will be able to extract from the RITS-Net exchanges, the main lessons to formulate their own ITS plans adapted to the specific local contexts. The poject will be summarised in the RITS-Net booklet and made available to other regions for further replication.
Safety of the oral factor XIa inhibitor asundexian compared with apixaban in patients with atrial fibrillation (PACIFIC-AF): a multicentre, randomised, double-blind, double-dummy, dose-finding phase 2 study

Direct-acting oral anticoagulant use for stroke prevention in atrial fibrillation is limited by bleeding concerns. Asundexian, a novel, oral small molecule activated coagulation factor XIa (FXIa) inhibitor, might reduce thrombosis with minimal effect on haemostasis. We aimed to determine the optimal dose of asundexian and to compare the incidence of bleeding with that of apixaban in patients with atrial fibrillation.In this randomised, double-blind, phase 2 dose-finding study, we compared asundexian 20 mg or 50 mg once daily with apixaban 5 mg twice daily in patients aged 45 years or older with atrial fibrillation, a CHA2DS2-VASc score of at least 2 if male or at least 3 if female, and increased bleeding risk. The study was conducted at 93 sites in 14 countries, including 12 European countries, Canada, and Japan. Participants were randomly assigned (1:1:1) to a treatment group using an interactive web response system, with randomisation stratified by whether patients were receiving a direct-acting oral anticoagulant before the study start. Masking was achieved using a double-dummy design, with participants receiving both the assigned treatment and a placebo that resembled the non-assigned treatment. The primary endpoint was the composite of major or clinically relevant non-major bleeding according to International Society on Thrombosis and Haemostasis criteria, assessed in all patients who took at least one dose of study medication. This trial is registered with ClinicalTrials.gov, NCT04218266, and EudraCT, 2019-002365-35.Between Jan 30, 2020, and June 21, 2021, 862 patients were enrolled. 755 patients were randomly assigned to treatment. Two patients (assigned to asundexian 20 mg) never took any study medication, resulting in 753 patients being included in the analysis (249 received asundexian 20 mg, 254 received asundexian 50 g, and 250 received apixaban). The mean age of participants was 73·7 years (SD 8·3), 309 (41%) were women, 216 (29%) had chronic kidney disease, and mean CHA2DS2-VASc score was 3·9 (1·3). Asundexian 20 mg resulted in 81% inhibition of FXIa activity at trough concentrations and 90% inhibition at peak concentrations; asundexian 50 mg resulted in 92% inhibition at trough concentrations and 94% inhibition at peak concentrations. Ratios of incidence proportions for the primary endpoint were 0·50 (90% CI 0·14-1·68) for asundexian 20 mg (three events), 0·16 (0·01-0·99) for asundexian 50 mg (one event), and 0·33 (0·09-0·97) for pooled asundexian (four events) versus apixaban (six events). The rate of any adverse event occurring was similar in the three treatment groups: 118 (47%) with asundexian 20 mg, 120 (47%) with asundexian 50 mg, and 122 (49%) with apixaban.The FXIa inhibitor asundexian at doses of 20 mg and 50 mg once daily resulted in lower rates of bleeding compared with standard dosing of apixaban, with near-complete in-vivo FXIa inhibition, in patients with atrial fibrillation.Bayer.
FOCUS: Shedding light on the high search response time in the wild

Response time plays a key role in Web services, as it significantly impacts user engagement, and consequently the Web providers' revenue. Using a large search engine as a case study, we propose a machine learning based analysis framework, called FOCUS, as the first step to automatically debug high search response time (HSRT) in search logs. The output of FOCUS offers a promising starting point for operators' further investigation. FOCUS has been deployed in one of the largest search engines for 2.5 months and analyzed about one billion search logs. Compared with a previous approach, FOCUS generates 90% less items for investigation and achieves both higher recall and higher precision. The results of FOCUS enable us to make several interesting observations. For example, we find that popular queries are more image-intensive (e.g., TV series and shopping), but they have relatively low SRT because they are cached well by servers. Additionally, as suggested by the first-month analysis results of FOCUS, we conduct an optimization on image transmission time. A one-month real-world deployment shows that we successfully reduce the 80th percentile of search response time by 253ms, and reduce the fraction of HSRT by one third.