SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Synthesis and Properties of Novel Rare Earth Luminescent Materials Sr(3-x)MgSi3O(10):Tbx(3+)

Novel rare earth luminescent materials Sr3-xMgSi3O10∶ Tb3x +were synthesized by gel-combustion method in activated carbon weak reductive environment. The formation process,phase structure,composition and luminescent properties of the as-synthesized phosphors were investigated by TG-DTA,infrared spectroscopy,X-ray powder diffraction,Energy Dispersive Spectrometer and Fluorescence spectrophotometer. The results show that Sr3-xMgSi3O10∶ Tb3+ phosphors possess the similar tetragonal crystal structure with Sr2MgSi2O7. The excitation spectrum of Sr3-xMgSi3O10∶ Tb3x +has a broad band from 200 nm to 300 nm,and the main peak is at 249 nm. The emission spectrum is composed of a series of peaks,located respectively at 491 nm,544 nm,586 nm,624 nm. These emission peaks are ascribed to Tb3+ transition from 5D4 to 7FJ( J =6,5,4,3). The main emission peak is at 544 nm due to the transition of 5D4→7F5,which results in a yellow-green emitting. In addition,it is found that the reductive temperature and the concentration of doped Tb3+ have great effects on the luminescent intensity of the sample,and the mechanism of concentration quenching was discussed.
Advanced intelligence and close-loop control for crystallisation of api’s (active pharmaceutical ingredients)

The project aims to address key challenges of the pharmaceutical industry related to the consistent supply of active pharmaceutical ingredients (APIs) which are formed through crystallisation processes. Over 80% of the worlds API’s have crystallisation steps. The current method of determining process performance is a combination of off-line analysis of the quality attributes of the API crystals after the crystallisation process is complete. This methodology does not control the manufacturing process and leads to a variable quality product, variable yields and a large proportion of rework batches, costing the API industry in excess of €10B/year. SmartCrys is an integrated solution for API processing issues of (1) in-line PAT Analysers to measure the critical quality attributes of the crystals, (2) Manufacturing Intelligence to interpret the data and decide whether process adjustments are required, (3) Process Automation which enable the automatic adjustment of the process to take place and (4) Data Analytics which enable visibility of all process data in real-time. SmartCrys enables rapid process development and subsequently self-adjustment of crystallization processes in real time, targeting an addressable market for SmartCrys of €20B. Through engagement with its customer base (8 of the top 10 Pharma companies worldwide) and the regulators, Innopharma have identified a technological gap in in-line process control among API manufacturers. SmartCrys will consolidate Innopharma’s position as one of the world’s leaders in Advanced Analytical Technologies within the pharmaceutical sector, and provide an opportunity to increase company turnover from €8M to €23M over the next 5 years and to grow staff from 45 to 65. It will also contribute to the continued competitiveness of the European API crystallization sector and help retain thousands of high-tech API manufacturing jobs within Europe.
Dynamical derivation of Eyring equation and the second-order kinetic law

Elementary gas-phase reactions of the bimolecular type A + B → Products are characterized by the second-order kinetic law , where [A] and [B] are the concentrations of A and B species, t is the time, and k is the rate constant, usually estimated by means of Eyring equation. Here, we show that its dynamical derivation, as such, is not consistent with the second-order law. This contradiction is however removed by introducing a correlation between what we call potentially reactive pairs. A new presentation of the dynamical derivation of Eyring equation is finally proposed on the basis of the previous findings. © 2010 Wiley Periodicals, Inc. Int J Quantum Chem 110:2355–2359, 2010
Early Pulmonary Tuberculosis: Diagnosis, Prognosis and Treatment.

In the publication of his small book on Early Pulmonary Tuberculosis, Dr. John B. Hawes, 2d, of Boston, has filled a longfelt want. As Dr. Richard C. Cabot writes in the preface of this work- There are plenty of large authoritative books about tuberculosis. There are plenty of small books which are not Doctor Hawes has written a book which is small and yet authoritative. In fifty-eight pages Doctor Hawes takes up the subject in a systematic concise manner, devoting a chapter each to the important facts of the family history, past history, work and habits, present illness, physical -examination, diagnosis, prognosis, and treatment. There are also important chapters on Adventitious Signs not Due to Pulmonary Disease; on Conditions which may Stimulate Tuberculosis; and on special methods of diagnosis and treatment such as the X-ray, tuberculin, and artificial pneumothorax. More might be added of the value of artificial pneumothorax in. early cases which are characterized by hemoptysis or by high fever or by both. A novel feature of this book is the appendix, which fills forty-eight pages, and which, by means of illustrative cases, photographs and X-ray plates of identical cases, etc., brings out many of the important points discussed in the first part of the book. If every physician would follow the advice given by Doctor Hawes, there would be many less cases of advanced pulmonary tuberculosis; this is particularly true in the case of children when the involvement of the bronchial glands should be recognized before the infection invades the lung tissue. Certainly there is no more important factor in the health of any community than the detection of early cases of pulmonary tuberculosis. Rae W. Whidden, M.D.
A technology marketplace for hospitality compliance services that integrates with public sector authorities and relieves the burden of regulation for businesses

The EU attaches the highest political priority to Better Regulation or ‘Smart Regulation’ which envisages a whole-of-government approach to the policy cycle extending from design to evaluation and revision.  The annual cost of regulation to business is conservatively estimated to 3.5% of EU GDP.  For the hospitality industry, the burden of regulation is proportionately greater owing to the high distribution of SME’s and increasing public safety and environmental control that drives a 4% increase in compliance costs year on year.  Trade bodies frequently cite regulations as unfair and anti-competitive.
SwiftComply has developed an innovative and exciting new approach to delivering and monitoring hospitality compliance.  Our solution creates a marketplace between food service businesses and compliance service providers. SwiftComply provides oversight of all transactions to regulators, allowing a real-time understanding of compliance activity and enabling them to focus on areas of non-performance. This is an efficient, business friendly and cost effective approach to reducing the burden of regulation and has worldwide application for food safety, building control, fire and environmental regulations.
SwiftComply has demonstrated the marketplace in the area of fat, oil and grease compliance in Dublin, Ireland and has commenced pilots in 3 US cities.  This Project has the objective of scaling up, refining and demonstrating our solution to meet the strong customer demand identified during Phase 1 market analysis. 
SwiftComply has raised private sector seed funding of €1.3m and will use H2020 funding to maximise speed to market and competitive advantage in Europe. SwiftComply has worldwide application and the potential to reach an annualised turnover of €63m, deliver a 86% gross profit margin, create over 600 jobs and digitise 4.5m pieces of paper by 2023.  Successful completion of this Project will lead directly to a Series A fundraising round and full market exploitation.
Self-Assembling plant-based hydrogels induced by redox enzymes

Celignis is an SME service provider focused on the compositional analysis of biomass for advanced biofuels and biorefinery applications. We are also active in several research projects related to the analysis, pre-treatment, and valorisation of biomass. Celignis is now expanding its horizons to develop innovative solutions for the production of biobased products, such as hydrogels from plant biomass.  SAPHIRE “Self-Assembling Plant-based Hydrogels Induced by Redox Enzymes” is a novel process designed to produce environmentally-friendly, 100% plant-based hydrogels for food, cosmetic and pharmaceutical applications. Hydrogels from natural polymers, especially polysaccharides, are non-toxic and biodegradable, unlike synthetic hydrogels.  The SAPHIRE process converts polysaccharides from underutilised agricultural residues to high-quality biobased hydrogels that can substitute for synthetic petroleum-based non-biodegradable hydrogels. The production of hydrogels from plant cell wall components using specially-designed enzyme cocktails is the key innovation of the SAPHIRE process.
 
Celignis aims to grow as an actor in the biobased products industry by implementing the disruptive innovating SAPHIRE technology. However, while the laboratory infrastructure and many of the key multidisciplinary skills required for advancing the concept exist at Celignis, the innovation project needs additional research and development, particularly in the area of enzymes and plant cell wall modifications.  An Innovation Associate, recruited through the Horizon 2020 INNOSUP programme, will complement the interdisciplinary innovation team of Celignis and fast-track the research to realise the potential of SAPHIRE. The Innovation Associate will benefit from integrating in Celignis’s dynamic and creative entrepreneurship environment and from training programs designed for personal and professional skills development and for setting a clear path to the scale-up and commercialisation of research.
Methods for a stage performance

Abstract Disclosed are methods that create the perception for an audience that an actor is being transported from one location to another during a stage performance. Also disclosed are methods for entrance onto/exit from a stage platform by an actor, or entrance onto/exit from a stage backdrop by a precision image that represents an actor. The disclosed methods involve interaction of an actor with an object/prop or image of an object/prop, and/or involve interaction of an image of an actor with an object/prop or image of an object/prop during a stage performance. WO 2019/106543 PCT/IB2018/059372 --2 1-0
Intimate partner violence against women during pregnancy in Tripura: a hospital based study

Background: Intimate partner violence is increasing day by day and has become a matter of public health concern. Methods: To estimate the prevalence of intimate partner violence during pregnancy, to find out the pattern of violence and its determinants, a hospital based cross-sectional study was conducted among 1005 women admitted in the maternity wards of Agartala Government Medical College and Mohanpur Community Health Centre using multistage sampling and structured interview schedule during 20 th November 2009 to 19 th November 2010. Descriptive statistics, chi-square test and binary logistic regression analysis were used. Results: Mean age of the study women was 23.21 (± 4.229). Prevalence of physical assault during pregnancy was 23.8 %, verbal abuse 40.6 %, forced intercourse 21.2 %. Violence was faced by 43.2 % women before pregnancy, and in 29.5 % cases, it continued during pregnancy also. 37.815 % violence occurred without any reason; 34.873 % due to financial matters, 12.605 % due to family affairs, 6.302 % for not giving birth to son, 8.403 % due to household work and suspicion of infidelity. Violence was more prevalent among Christian, daily labours (n = 31, 75.6%) , illiterate and rural women. Women faced more violence from addicted husbands (n = 239, 26.3%) and in families where decision makers were illiterate (n = 201, 47.2%) . Conclusions: Improving literacy, eliminating addiction and marriage of women with men of lesser age difference may help in minimizing intimate partner violence in Tripura.
Self-quenchable biofunctional nanoparticles of heparin–folate-photosensitizer conjugates for photodynamic therapy

Abstract Novel amphiphilic polysaccharide/PS conjugates synthesized by chemical conjugation of heparin with a hydrophobic photosensitizer (PS), pheophorbide a (PhA), and a targeting ligand, folate, were investigated for their potential application in photodynamic therapy (PDT). The anticoagulant activity of heparin-PhA (HP) and folate–heparin–PhA (FHP) conjugates was significantly decreased compared to that of heparin, thereby potentially reducing the hemorrhagic side effects. The critical self-quenching concentrations of the conjugates were decreased as the content of PhA rose. HP and FHP conjugates formed nano-sized particles in aqueous medium through a self-assembling process, and the nanoparticles were 130–170 nm in size, with a unimodal pattern of size distribution. Photoactivity of HP and FHP nanoparticles was evaluated by measuring the generation of singlet oxygen in DMF and PBS. The nanoparticles displayed a self-photoquenching effect in PBS, while the generation of singlet oxygen dramatically increased in DMF. HP and FHP nanoparticles exhibited marked phototoxicity on HeLa cells and were minimally dark-toxic without light treatment.
Chalcogenides for solar applications

In its “Strategic Research Agenda for Photovoltaic Solar Energy Technology”[1], the European Union has set a target for solar generated electricity to become competitive with conventional electricity generation by 2020–2030. Second generation thin-film chalcogenide materials are among the most promising candidates for large-scale PV manufacturing and are quickly becoming commercial products. These materials offer stable and efficient (above 10%) photovoltaic modules fabricated by scalable thin-film technologies and cell efficiencies above 20 % (CIGS). CIGSe thin films were deposited by RF magnetron sputtering at room temperature from a single quaternary target on various substrates producing stoichiometric films. Cu2ZnSnS4 thin films were fabricated using a novel two stage process incorporating RF magnetron sputtering from a single target and then annealed in a rapid thermal processor without any toxic gases or reactive sulphur. GaLaS thin films were deposited by a patented high throughput PVD MBE System. The effect of the annealing temperature on the sulphur in the films was investigated. The XRD phase analysis confirms the preference of GLS to oxidise to form a more stable compound. The films were also analysed by ellipsometry, EDX and Raman. CuSbS2 thin films were fabricated using two techniques. Firstly, using an atmospheric pressure chemical vapour deposition system. CuSbSx was successfully deposited on soda lime substrates at a very fast rate of around 35 µm in 1 hour. For RF sputtering two and single stage depositions were carried out. By two stages, the films were annealed at various temperatures (250° to 325°) and times (5 to 60 min). The annealing was done without any toxic gases or reactive sulphur. Single phase CuSbS2 films with good adhesion, good crystallinity and with no apparent sulphur loss can be achieved. By a single stage process, CuSbS2 crystals were made in situ by depositing at 200° and 250°. The grain sizes were measured by SEM imaging, and grains above 1 µm can be fabricated. The effect of etching with bromine and HCl was also investigated. The cells made showed a high current density using CuSbSx films (up to 1-2 mA/cm2).
Comparative methods for PET image segmentation in pharyngolaryngeal squamous cell carcinoma

Several methods have been proposed for the segmentation of ¹⁸F-FDG uptake in PET. In this study, we assessed the performance of four categories of ¹⁸F-FDG PET image segmentation techniques in pharyngolaryngeal squamous cell carcinoma using clinical studies where the surgical specimen served as the benchmark.Nine PET image segmentation techniques were compared including: five thresholding methods; the level set technique (active contour); the stochastic expectation-maximization approach; fuzzy clustering-based segmentation (FCM); and a variant of FCM, the spatial wavelet-based algorithm (FCM-SW) which incorporates spatial information during the segmentation process, thus allowing the handling of uptake in heterogeneous lesions. These algorithms were evaluated using clinical studies in which the segmentation results were compared to the 3-D biological tumour volume (BTV) defined by histology in PET images of seven patients with T3-T4 laryngeal squamous cell carcinoma who underwent a total laryngectomy. The macroscopic tumour specimens were collected "en bloc", frozen and cut into 1.7- to 2-mm thick slices, then digitized for use as reference.The clinical results suggested that four of the thresholding methods and expectation-maximization overestimated the average tumour volume, while a contrast-oriented thresholding method, the level set technique and the FCM-SW algorithm underestimated it, with the FCM-SW algorithm providing relatively the highest accuracy in terms of volume determination (-5.9 ± 11.9%) and overlap index. The mean overlap index varied between 0.27 and 0.54 for the different image segmentation techniques. The FCM-SW segmentation technique showed the best compromise in terms of 3-D overlap index and statistical analysis results with values of 0.54 (0.26-0.72) for the overlap index.The BTVs delineated using the FCM-SW segmentation technique were seemingly the most accurate and approximated closely the 3-D BTVs defined using the surgical specimens. Adaptive thresholding techniques need to be calibrated for each PET scanner and acquisition/processing protocol, and should not be used without optimization.
DISTANCE METER AND DISTANCE MEASURING SYSTEM

The invention relates to a distance meter (1), especially a laser distance meter, comprising means for continuously measuring a distance between a reference point (7) of the distance meter (1) and an interspaced element (5, 16). The invention is characterized by means (21) for signaling a direction of adjustment in which the distance meter (1) has to be adjusted in relation to the interspaced element (5, 16) and/or the interspaced element (5, 16) in relation to the distance meter (1) to adjust a definable distance between the reference point (7) of the distance meter (1) and the interspaced element (5, 16). The invention also relates to a distance measuring system.
Biophysical mechanisms of long-range transcriptional regulation

In mammals, transcriptional control of many genes relies on cis-regulatory elements such as enhancers, which are often located tens to hundreds of kilobases away from their cognate promoters. Functional interactions between distal regulatory elements and target promoters require mutual physical proximity, which is linked to the three-dimensional structure of the chromatin fiber. Chromosome conformation capture studies revealed that chromosomes are partitioned into Topologically Associating Domains (TADs), sub-megabase domains of preferential physical interactions of the chromatin fiber. Genetic evidence showed that TAD boundaries restrict the genomic range of enhancer-promoter communication, and that interactions between regulatory sequences within TADs are further fine-tuned by smaller-scale structures. However, the mechanistic details of how physical interactions translate into transcriptional outputs are totally unknown. Here we propose to explore the biophysical mechanisms that link chromosome conformation and long-range transcriptional regulation using molecular biology, genetic engineering, single-cell experiments and physical modeling. We will measure chromosomal interactions in single cells and in time using a novel method that relies on an enzymatic process in vivo. Genetic engineering will be used to establish a cell system that allows quantitative measurement of how enhancer-promoter interactions relate to transcription at the population and single-cell levels, and to test the effects of perturbations without confounding effects. Finally, we will develop physical models of promoter operation in the presence of distal enhancers, which will be used to interpret the experimental data and formulate new testable predictions. With this integrated approach we aim at providing an entirely new layer of description of the general principles underlying transcriptional control, which could establish new paradigms for research in epigenetics and gene regulation.
Nursing Perspectives on Person- and People-Centered Integrated Care for All

Person-centeredness resides at the heart of nursing and nurses also place people at the centre of their activities to achieve a healthier society. The commitment of the International Council of Nurses (ICN) to deliver person- and people-centered care is evident in the ICN Code of Ethics for Nurses [1], ICN policy papers and is translated into various guidelines, programmes and research. Person- and people-centered healthcare requires not only commitment of individual nurses and other healthcare workers but also changes in healthcare systems including service delivery systems and other structures. It is necessary to take a whole government approach where person- and people-centered healthcare is considered by all ministries including non-health sectors. Active involvement of care recipients, nurses and other healthcare professionals in healthcare design and decision making is essential to achieve person- and people-centered healthcare.
Time series geophysical monitoring of permanganate injections and in situ chemical oxidation of PCE, OU1 area, Savage Superfund Site, Milford, NH, USA

In situ chemical oxidation (ISCO) treatment with sodium permanganate, an electrically conductive oxidant, provides a strong electrical signal for tracking of injectate transport using time series geophysical surveys including direct current (DC) resistivity and electromagnetic (EM) methods. Effective remediation is dependent upon placing the oxidant in close contact with the contaminated aquifer. Therefore, monitoring tools that provide enhanced tracking capability of the injectate offer considerable benefit to guide subsequent ISCO injections. Time-series geophysical surveys were performed at a superfund site in New Hampshire, USA over a one-year period to identify temporal changes in the bulk electrical conductivity of a tetrachloroethylene (PCE; also called tetrachloroethene) contaminated, glacially deposited aquifer due to the injection of sodium permanganate. The ISCO treatment involved a series of pulse injections of sodium permanganate from multiple injection wells within a contained area of the aquifer. After the initial injection, the permanganate was allowed to disperse under ambient groundwater velocities. Time series geophysical surveys identified the downward sinking and pooling of the sodium permanganate atop of the underlying till or bedrock surface caused by density-driven flow, and the limited horizontal spread of the sodium permanganate in the shallow parts of the aquifer during this injection period. When coupled with conventional monitoring, the surveys allowed for an assessment of ISCO treatment effectiveness in targeting the PCE plume and helped target areas for subsequent treatment.