SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Energy efficient pathway for the city transformation: enabling a positive future

MAKING-CITY is a large-scale demonstration project aiming at the development of new integrated strategies to address the urban energy system transformation towards low carbon cities, with the positive energy district (PED) approach as the core of the urban energy transition pathway.  The project will be intensively focused on achieving evidences about the actual potential of the PED concept, as foundation of a high efficient and sustainable route to progress beyond the current urban transformation roadmaps. Although in principle a PED approach seems a solid and ambitious strategy, this should be complemented with long term urban planning to ensure upscaling and fostering higher impacts. Currently city energy plans are starting to be designed with a 2030 horizon, according to the standard city commitments, as for instance those reflected in the SECAPs and other more specific city plans.  Project will address methodologies to support cities in their long term urban planning towards an adequate energy transition, paving the way of the planning, implementation and up-scaling process.  Cities of Groningen (Netherlands) and Oulu (Finland) will act as lighthouses. These cities are currently working intensively in ambitious transformation planning whose approaches fit perfectly with the project objectives. Both have committed to deploy a demonstration of at least one positive energy district. León (Spain), Bassano del Grappa (Italy), Kadiköy (Turkey), Poprad (Slovakia), Vidin (Bulgaria) and Lublin (Poland) will be the follower cities. All of them have assumed a huge commitment to develop a solid execution project of Positive Energy District and foster high level of replication of the solutions demonstrated in Groningen and Oulu.
High Altitude Medicine Applications on Mount Blanc

e-Rés@mont's objective is to improve health security in the mountains, through the development, the implementation and the promotion of advanced local services of High Altitude Medicine, based on the technologies of e-medicine and remote consultancy. The targeted publics are residents, tourists and Mountain-professionals. Through the strengthening of the health services of the most isolated territories, the project contributes in the fight against depopulation and in the improvement of tourism. The project foresees some practices for the prevention and treatment of High Altitude Pathologies. In particular, the focus will be on altitude sickness, exposure's proper medications and on the realization of a research about physio-pathological responses to high altitude. Another genetic research on athletes’ performance during resistance competitions in high altitude is planned.
On the Forefront of Manufacturing Technology Applications in the Machinery Manufacturing Industry

The human society coming into the 20th century,increases demand for material.With the gradual formation of global market integration,the world's fierce competition is growing,increasing quality of life of the world's energy requirements and the reduction and population growth contradictions become more prominent.Therefore,the social development of its economic support for the industry-machinery manufacturing and the technical system of a higher requirement.Requirements of the manufacturing industry with more rapid and flexible response to market,higher product quality,lower costs and energy consumption,and good environmental properties.This needs prompted the traditional manufacturing industry in the 20th century begining a new revolutionary change,traditional manufacturing which began to develop modern manufacturing.This paper also discussed application of manufacturing technology in mechanical manufacturing industry.
Decoding spatio-temporal omics in progressive neuroinflammation

Multiple sclerosis (MS) is a paradigmatic progressive neuroinflammatory disease characterized by multiple lesions across the entire central nervous system including both gray and white matter areas. Deconvoluting the spatio-temporal cellular and molecular landscape is therefore key to understanding underlying disease mechanisms and to develop cell-type specific therapies. The DecOmPress proposal is about integrative human and mouse single-cell genomic strategies to track-down reactive cellular states in compartmentalized progressive neuroinflammation. DecOmPress has two major research tracks (RTs).

RT1 is an MS tissue discovery pipeline utilizing single-nucleus RNA and open chromatin sequencing. RT1 is about developing novel integrative computational tools to process sequencing data from different anatomical lesion areas implementing a large multiplex single-nucleus genomic dataset from the anterior visual system. RT1 is also about decoding compartmentalized inflammation in meningeal versus perivascular tissue niches.

RT2 is a functional validation pipeline utilizing complex transgenic and disease mouse models as well as human organoids in combination with single-cell physiology and genomics. RT2 is about dissecting glial-intrinsic mechanisms at the chronically inflamed white matter lesion rim focusing on MS-specific oligodendrocyte and microglia subtypes. RT2 is also about decoding neuron subtype specific pathologies focusing on projection neurons and the contribution of local (meningeal) and distant (white matter tracts) inflammation and demyelination to cell-type specific neurodegeneration.

In summary, DecOmPress is a highly innovative and fully translational multidisciplinary proposal aiming at identifying novel cell-type specific disease mechanisms and therapeutic targets.
Solutions and interventions for the technological transfer and the innovation of the agro-food sector in South East regions

TECH.FOOD, tackles the topic of innovation of the agro-food sector, one of the major components of the SEE economies in terms of turnover, number of SMEs and persons employed. The project arises from the necessity of common strategies, tools, and opportunities to promote R&TD and innovation in the agro-food sector, facing the fast decreasing competitiveness of SEE agro-food enterprises. Project will be developed by institutions and scientific bodies spread across 7 SEE regions representative of the SEE space. Main TECH.FOOD objective consists in building R&TD and innovation capacity of the agro-food sector, overcoming the lack of links among research bodies, institutions and enterprises, coherently to the Lisbon strategy goals. Project activities are organized in 7 work packages, developed according to a multi-level methodology that foreseen the direct participation and commitment of target groups and stakeholders throughout the whole project implementation. Project starts from a deep analysis highlighting innovation needs and potentials of agro-food SMEs, to be performed at local level according to a transnational methodology. Regional profiles obtained by the analysis represent the base for all further activities. The establishment of a transnational network among involved regions will allow to create new opportunities of innovation and business among regional target groups, that will be hold in local networks by the operation of the project Technological Transfer Nodes realized by partners. Concrete innovation will be fostered by applying an Innovation Toolbox addressed to enterprises and research centres, with the catalyst action played by institutions. Tools application will allow to trigger, already during project lifecycle, R&TD and innovation processes in all concerned regions, also through the participation to EU financial instruments for competitiveness. After project end, a wide critical mass of innovation potentials is expected to be expressed.
subvención de capital de trabajo para A& SZ Spółka z o.o. Sp.kom.

El proyecto se refiere al apoyo del empresario a proporcionar liquidez financiera y apoyo a las actividades actuales debido a las dificultades financieras experimentadas por el empresario como consecuencia del brote de COVID-19. Ayuda financiera concedida en el marco del programa n.º SA.57015 (2020/N)
DOES BANNING PRICE DISCRIMINATION PROMOTE ENTRY AND INCREASE WELFARE? A MODEL OF DIFFERENTIATED-PRODUCT DUOPOLY WITH ASYMMETRIC MARKETS*

In this paper we investigate the impact of firms' pricing policies upon entry and welfare under duopoly price competition and product differentiation. We consider a model where an incumbent serves two distinct and independent geographical markets and an entrant may enter in one of the markets. Our results show that discriminatory pricing may be either more, less or equally favorable to entry than uniform pricing. The welfare effect of banning price discrimination is also ambiguous. However, the case for banning price discrimination is much weaker than under monopoly. Interestingly, discriminatory pricing may yield higher welfare even when entry occurs only under uniform pricing.
Non-uniform spatial difference in the South Asian summer monsoon during the mid-Piacenzian

AbstractThe South Asian summer monsoon (SASM) during the mid-Piacenzian is analyzed through climate modelling with CAM4. The model results reveal a non-uniform spatial difference in the SASM during the mid-Piacenzian compared to the pre-industrial era, with the SASM being more intense north of ~20°N but weaker south of ~20°N. In particular, summer precipitation is higher in South Asia north of ~20°N, accompanied by anomalous low-level southwesterlies from the Arabian Sea, whereas the precipitation is lower in South Asia south of ~20°N, with anomalous low-level easterlies. These differences in the SASM are related to changes in sea level pressure (SLP) due to the different boundary conditions between the two periods. Further analysis isolates the climate effects of the different boundary conditions and indicates the combined difference in atmospheric carbon dioxide concentration and SST to be the most important factor in this difference in the SASM through the changes in SLP. By comparison, the differences...
Thermomechanical controls on magma supply and volcanic deformation: application to Aira caldera, Japan

Ground deformation often precedes volcanic eruptions, and results from complex interactions between source processes and the thermomechanical behaviour of surrounding rocks. Previous models aiming to constrain source processes were unable to include realistic mechanical and thermal rock properties, and the role of thermomechanical heterogeneity in magma accumulation was unclear. Here we show how spatio-temporal deformation and magma reservoir evolution are fundamentally controlled by three-dimensional thermomechanical heterogeneity. Using the example of continued inflation at Aira caldera, Japan, we demonstrate that magma is accumulating faster than it can be erupted, and the current uplift is approaching the level inferred prior to the violent 1914 Plinian eruption. Magma storage conditions coincide with estimates for the caldera-forming reservoir ~29,000 years ago, and the inferred magma supply rate indicates a ~130-year timeframe to amass enough magma to feed a future 1914-sized eruption. These new inferences are important for eruption forecasting and risk mitigation, and have significant implications for the interpretations of volcanic deformation worldwide.
Experimental treatments for mitochondrial dysfunction in sepsis: A narrative review.

Sepsis is a systemic inflammatory response to infection. Sepsis, which can lead to severe sepsis, septic shock, and multiple organ dysfunction syndrome, is an important cause of mortality. Pathogenesis is extremely complex. In recent years, cell hypoxia caused by mitochondrial dysfunction has become a hot research field. Sepsis damages the structure and function of mitochondria, conversely, mitochondrial dysfunction aggravated sepsis. The treatment of sepsis lacks effective specific drugs. The aim of this paper is to undertake a narrative review of the current experimental treatment for mitochondrial dysfunction in sepsis. The search was conducted in PubMed databases and Web of Science databases from 1950 to January 2014. A total of 1,090 references were retrieved by the search, of which 121 researches met all the inclusion criteria were included. Articles on the relationship between sepsis and mitochondria, and drugs used for mitochondrial dysfunction in sepsis were reviewed retrospectively. The drugs were divided into four categories: (1) Drug related to mitochondrial matrix and respiratory chain, (2) drugs of mitochondrial antioxidant and free radical scavengers, (3) drugs related to mitochondrial membrane stability, (4) hormone therapy for septic mitochondria. In animal experiments, many drugs show good results. However, clinical research lacks. In future studies, the urgent need is to develop promising drugs in clinical trials.
A new species of Microlepidogaster (Loricariidae: Hypoptopomatinae) from rio Pardo, a coastal drainage in eastern Brazil

A new species of Microlepidogaster is described from rio Pardo drainage, a coastal basin in eastern Brazil. This species can be differentiated from its congeners by having the following unique features: 1) anterior portion of snout with a large odontode-free band extending laterally from the anterior tip of snout to the postrostral plate 2; 2) transverse process of second dorsal-fin pterygiophore exposed and bearing odontodes; and 3) exposed area of pectoral girdle extended to the mesial symphysis, with odontodes mainly distributed in the coracoid ventral expansion. The new species is further distinguished by several other morphological non-exclusive features. Recently, some Microlepidogaster species were reallocated to Rhinolekos. The taxonomic changes involving these genera is herein discussed.
How to help the hive? incidence and impact of heritable microbes on bee health

Honey bees provide both economic and societal benefits, from the honey and other commodities that they produce to the pollination services they provide. The loss of honey bee colonies and the current threats to their health are of considerable concern to bee-keepers and biologists alike. This project seeks to examine how a particular aspect of honey bee biology – the symbiotic microbiome – impacts upon honey bee health. Studies in other systems reveal heritable microbes as important modulators of disease susceptibility. This project will utilize the extensive network of bee samples across the US and UK to establish geographical patterns of heritable microbe presence in bees, and links to apiculture practice. It will then use state of the art transcriptomic and genomic approaches to establish the links between Arsenophonus, a heritable symbiont known in bees, and bee health. It will then, combine with professional agencies responsible for bee health to use these results to modify apiculture practice to establish better bee husbandry.  Aside the research science completed, the project will train an EU scientist in state of the art genomic technologies and translation from discovery to applied science. It will further transfer the training gained to EU hosts, both in discovery science and application.
Revolutionize the way humans interact with technology

Mobile Augmented Reality has the potential to go beyond gaming and transform the way we learn, work and interact. The main issue with mobile AR so far has been that a seemingly simple task, that is to create a real time understanding of how the hand moves by using only the already installed RGB camera and the processing power available in a mobile phone has been an unsolved technical problem. 
ManoMotion taps into this opportunity with its patented deep technology that integrates hand tracking and gesture analysis with Computer Vision, AI and Machine learning in a B2B solution that provides a framework for real- time 3D gestural analysis with the simple RGB camera found in everyday smartphones, with minimal computing power and minimal battery consumption. ManoMotion’s is the first software solution that creates realistic real-time hand understanding, gesture control & hand-to-object interaction in augmented reality and virtual reality environments. The company is on a mission to interpret human intent and make technology more natural and intuitive using one of the most versatile tools humans use to interact with the world: their hands. With the “RealHands” project, the company will push the development of the technology to be scalable and adaptable to a virtually endless range of applications: from videogaming to education to health applications.
Goldman Sachs estimate that the total accessible market for AR software is 35 B$ in 2025 60% of which is driven by consumers. The largest segment, according to the same study, is projected to be the videogame market which is expected to generate 11.6 B$ from over 216M users in 2025, followed by health case sector at 5.1 B$ and engineering 4.7 B$. Thanks to this project ManoMotion will become a prime mover of this market.
Bacterial adhesion control through surface targeted regulation

Fundamental investigations of bacterial adhesion will create the knowledge base to advance surface engineering approaches.
Directed mutagenesis of adhesin genes in several oral pathogens will be used to create a library of knockout strains. Recombinant adhesins will also be over-expressed in E.coli. Assays will be developed to test the interaction of the resulting strains (wild-type, knockouts, over-expressing E.coli clones) with a range of materials, covering the entire spectrum of surface properties with defined roughness, hydrophobicity, porosity, charge and composition. Adhesion kinetics will be monitored in real time, using flow cells to mimic the shear stress and nutrient exchange on implants in vivo. This will complement plate-based fluorescence adhesion assays, western blotting, immunofluorescence microscopy, and ELISAs. Adhesion trends will be tested with targeted surface modifications in pure and mixed culture, creating a feedback-loop for assay improvement with gradually specialised surface functionalization. The ultimate goal is to develop surfaces that promote the adhesion of host tissue, such as human osteoblast cells or gingival cells, whilst still preventing pathogen adhesion. 
Understanding the fundamental interactions of bacteria with surfaces facilitates the transferability of the results from this project to a variety of further applications (e.g. adhesion of electrogens to microbial fuel cell electrodes; antifouling surfaces etc.). My proposal therefore has the potential to be high impact research, and generates the framework for future interdisciplinary projects.
Automated pointing and control of high resolution cameras using video analytics

An automated method for cueing a high resolution video camera to a mobile object involves first detecting the presence of an object by a wide-area surveillance asset such as a radar and using the radar's positional information to cue the video camera iteratively, while updating the positional information each time. Then, a video analytics algorithm detects the object and generates more accurate positional and rate information on the object, which is then used to cue the video camera into a higher resolution setting for classifying/identifying the object. Once the object is identified, the positional and rate information is updated and the updated information is used to further cue the video camera into a higher resolution setting for recording a video clip of the moving object while the video camera is dynamically steered.
Delayed publication of vaccine trials

Why are we waiting? Sponsors, authors, and editors all contribute to delays

Among medical interventions to improve human health, vaccination has been and remains one of the most important.1 Given the huge number of deaths from influenza pandemics in recent history, the ability to rapidly develop effective vaccines for new strains of influenza is particularly critical. Making and testing a new influenza vaccine that can be administered to the public takes six months or less.2 For example, the pandemic A/H1N1 2009 influenza strain was first identified in April of 2009; four vaccines were approved by the US Food and Drug Administration in September. After the approval of a vaccine, however, important questions remain regarding dosage, effectiveness, and safety. These questions are best answered by randomized clinical trials, and getting complete results from these trials to policy makers, clinicians, and the general public in a timely manner is essential.

The problems of delayed publication and non-publication of clinical trials have been described in a variety of settings.3 4 5 In this issue of The BMJ , Manzoli and colleagues (doi:10.1136/bmj.g3058) examine delays to publication and non-publication for the vitally important area of vaccine trials.6 The authors searched …
Improved delay-range-dependent stability analysis of a time-delay system with norm bounded uncertainty

This paper presents improved robust delay-range-dependent stability analysis of an uncertain linear time-delay system following two different existing approaches - (i) non-delay partitioning (NDP) and (ii) delay partitioning (DP). The derived criterion (for both the approaches) proposes judicious use of integral inequality to approximate the uncertain limits of integration arising out of the time-derivative of Lyapunov-Krasovskii (LK) functionals to obtain less conservative results. Further, the present work compares both the approaches in terms of relative merits as well as highlights tradeoff for achieving higher delay bound and (or) reducing number of decision variables without losing conservatism in delay bound results. The analysis and discussion presented in the paper are validated by considering relevant numerical examples.
The effects of urbanization on insect diversity and human-nature interactions

Urbanization, one of the most extreme human-induced landscape changes on Earth, yields an important trade-off between development and biodiversity conservation. Recent research highlights the relevance of considering urban landscape organization (land-sharing or land-sparing development) to advance in this debate. However, there are still few studies on the topic, mostly local, on low diversity areas or focused on few taxonomic groups preventing generalization of results. The lack of research on urban insect diversity is remarkable despite their high economic, social and ecological importance. Human-nature interactions also play a critical role in the debate on how to create nature-friendlier and healthier cities, particularly regarding urban landscape organization. This interdisciplinary project aims to provide novel and useful information to this debate by (1) studying the impact of urbanization on multiple components of insect diversity (taxonomic and phylogenetic) in an understudied hotspot (Mediterranean region); (2) exploring if land-sharing or sparing urban areas hold different insect diversity levels; and (3) investigating the influence of urban landscape organization on subjective wellbeing and extinction of experience, critical for human-nature interactions. A complete methodological approach including classic taxonomic procedures, modern metabarcoding tools, and a solid study design combining spatial, temporal and taxonomic replicates grant the generalization of findings. Furthermore, through the use of innovative machine learning techniques, this project will also provide a useful open-access tool for researchers, city planners and citizens that will predict insect diversity and human-nature interactions in non-sampled urban areas. To do so, I will be trained by world experts in the analytical and applied aspects of this highly integrative project (Urban Ecology, Genetics, Sociology, and Computer Sciences), helping me to become an independent researcher