SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Dronedarone for Atrial Fibrillation

Dronedarone is a new antiarrhythmic agent that was recently approved for the prevention of cardiovascular hospitalization driven by atrial fibrillation/flutter. Its approval was based largely on the results of the ATHENA (A Placebo-Controlled, Double-Blind, Parallel Arm Trial to Assess the Efficacy of Dronedarone 400 mg bid for the Prevention of Cardiovascular Hospitalization or Death From Any Cause in Patients With Atrial Fibrillation/Atrial Flutter) trial, which demonstrated a significant 24% reduction in the combined end point of all-cause mortality and cardiovascular hospitalization, primarily driven by the latter. However, several other clinical trials have evaluated the impact of dronedarone on various cardiovascular end points and yielded mixed results. In this article, we summarize the available evidence concerning dronedarone, and offer practical recommendations to health care providers regarding its use in the treatment of atrial fibrillation. We conclude that the available data support the use of dronedarone in select patient populations as a second- or third-line agent.
BLUE GROWTH SMART ADRIATIC IONIAN S3

In the Adriatic-Ionian regions Blue Growth Innovation policies are characterized by a fragmented situation, with pioneering and lagging regions searching for a joint knowledge-based approach to their innovation strategies to enhance the blue growth sectors in their territories.
Moreover,regions and countries overlooking the same seas and rivers need harmonized Blue growth policies to plan future innovation initiatives on topics such as sea transport,water pollution,energy connectivity,marine environment protection, promotion of sustainable tourism etc.
Through the development of a Macro-Regional S3 on Blue Growth and the setting up of a dedicated Innovation Community,BLUEAIR aims at enhancing institutional capacities of ADRION territories in the definition of a common S3 policy on Blue Growth and guaranteeing the alignment of local initiatives with the EUSAIR strategy.Adopting a coordinated approach will improve administrative capacities, innovativeness, and economic development for participating territories as well as for the whole ADRION area.
Improving competences of innovation players on Blue Growth,identifying sectors of macro-regional interest, exploiting potentials for transnational cooperation,supporting the development of a single Macro-Regional S3 on BG in the Adriatic- Ionian:these objectives are reached by the involvement of the quadruple helix actors in the definition of a common strategic vision by means of enabling tools, capacity building initiatives and effective EDP practices and instruments.Supported by scientific experts and technical documentation, BLUEAIR offers to quadruple helix actors a view on the future scenarios of the Blue Growth sectors enabling them to take advantage of the sector transnational opportunities.2 seas, many untapped market opportunities in Blue Growth, different coastal and inland territories involved moving toward one single approach: the BLUEAIR Macro-Regional S3 on Blue Growth!
Relapsing–Remitting Multiple Sclerosis: Patterns of Response to Disease-Modifying Therapies and Associated Factors: A National Survey

Current treatments for relapsing-remitting multiple sclerosis (RRMS) are only partially effective. The objective of this study was to characterize treatment response in RRMS patients in Portugal to 12-month therapy with first-line disease-modifying therapies.In this retrospective study, neurologists at participating centers completed survey questionnaires using records of patients with RRMS who had received first-line treatment with one of five European Medicine Agency-approved agents in the 12 months prior to inclusion in the survey. Sub-optimal responders included patients treated for at least 1 year, and who had ≥1 relapse(s) or an increase of 1.5 points on the Expanded Disability Status Scale (EDSS; if baseline EDSS was 0) or an increase of ≥0.5 points (baseline EDSS ≥1). Optimal responders included patients treated for at least 1 year without relapse and who had an increase of <1.5 points on EDSS (if baseline EDSS was 0) or no increase in EDSS (baseline EDSS ≥1).Data for 1,131 patients from 15 centers were analyzed. Twenty-six percent (95% confidence interval 23-28%) of patients had sub-optimal treatment response. Duration of therapy (P < 0.001), age at the start of therapy (P = 0.03), and baseline EDSS score (P < 0.001), were significantly different among treatments. Sub-optimal treatment response appeared to be related only to a more severe EDSS score at baseline and did not differ among therapies.Neurologists should closely monitor patients to optimize treatment strategies and better control disease, improving prognosis.
Analysis, verification, and synthesis for infinite-state systems

The central objective of this project is to investigate key algorithmic verification questions concerning two fundamental mathematical structures used to model and analyse infinite-state systems, namely discrete linear dynamical systems and counter automata, in both ordinary and parametric form. Motivated especially by applications to software model checking (more specifically the termination of linear loops and predicate abstraction computations), as well as parametric real-time reasoning and the verification of Markov chains, we will focus on model-checking, module-checking, and synthesis problems for linear dynamical systems and one-counter automata against various fragments and extensions of Linear Temporal Logic (LTL) specifications. The key deliverables will be novel verification algorithms along with a map of the complexity landscape. A second objective is then to transfer algorithmic insights into practical verification methodologies and tools, in collaboration with colleagues in academia and industrial research laboratories.

We will build on a series of recent advances and breakthroughs in these areas (some of which from the PI’s team) to attack a range of specific algorithmic problems. We believe that this line of research will not only result in fundamental theoretical contributions and insights in their own right—potentially answering mathematical questions that have been open for years or even decades—but will also impact the practice of formal verification and lead to new and more powerful methods and tools for the use of engineers and programmers.
Morphological and morphometric characterization of agoutis' peripheral blood cells (Dasyprocta prymnolopha, wagler, 1831) raised in captivity

Thirty adult agoutis (Dasyprocta primnolopha) from the Nucleus of Study and Preservation of Wild Animals at the Federal University of Piauí were used. Blood scrubs of these animals were colored by the Leishman method and analyzed in light microscopy. The cells had been measured using programs that analyze images (Leica QWin - Image Processing and Analysis Software). Mature erythrocytes, basophil reticulocytes, lymphocytes, eosinophils, neutrophils, monocytes, and thrombocytes were identified. Agoutis' erythrocytes presented elliptical form, without nucleus with an average diameter of 5.64 micromeres ± 0.38. The lymphocytes are spherical cells with scarce cytoplasm, dense and with a very centralized rounded nucleus measuring an average diameter of 13.20 micromeres ± 0.35. The monocytes are slightly basophilic, with a spherical nucleus, central constriction, and an average diameter of 20.59 micromeres ± 0.32. The neutrophils are spherical, with a polymorphic lobulated nucleus, with an average diameter of 11.2 micromeres ± 0.20. The eosinophils are spherical with lobulated nucleus and with an average diameter of 14.25 micromeres ± 0.36. Only five basophils were observed, with abundance of cytoplasmic granules with 9.8 micrometers of diameter ± 0.30. Thrombocytopenic pleomorphism was frequent. There were similarities in the cellular constituents in peripheral blood of agoutis and of other rodents and humans. The cellular types from the peripheral blood, the morphology, and morphometry of the blood's cells did not vary according to sex.
AMPLIFICATION APPARATUS AND AMPLIFICATION METHOD

In an amplification apparatus according to the present disclosure, a combining unit combines an output signal of a first amplifier provided at a first branch with an output signal of a second amplifier provided at a second branch and outputs the combined signal. A non-linearity compensation unit multiplies an input baseband signal by a non-linearity compensation coefficient for compensating non-linearity of the entire apparatus, a first deviation compensation unit multiplies a first branch signal by a first deviation compensation coefficient for compensating an inter-branch deviation, and a second deviation compensation unit multiplies a second branch signal by a second deviation compensation coefficient for compensating the inter-branch deviation. A compensation coefficient calculation unit calculates the non-linearity compensation coefficient, the first deviation compensation coefficient, and the second deviation compensation coefficient based on the input baseband signal and a feedback baseband signal obtained by feeding back the combined signal.
Transit time flow meter probe

A transit time flow sensor is configured as an insertable probe carrying a pair of transducers spaced apart along an acoustic path. The transducers are attached to respective tabs extending outwardly from the ends of a tubular member and skewed with respect to an axis of the tube so that acoustic signals from one of the transducers are reflected from an interior portion of the tube and subsequently detected by the other transducer.
Adaptive array antenna for WLAN: A smart approach to beam switching through phase shifting in feed network

The WLAN is operated in some high traffic area where the radiation beam produced by the antenna is to be utilized with optimum efficiency. The aim of those antennas is to produce some directive and switched beams rather than producing Omni-directional pattern since these beam patterns are considered to be wastage in some non-used or low traffic areas. Hence, the antenna systems producing the directive and switched beams should be highly preferred for the WLAN application. A smart antenna array system performs the adaptive beam forming by focusing the beam in the desired direction and creating nulls in other directions to avoid the interference and the wasting of the beams. This is performed by the operating the phase shifting in its feed network and different ports. This paper investigates the performance of the different array patterns with different phase shifting for the optimum performance of the WLAN applications in a high congested indoor environment.
COMPOSITE ELECTRICAL CONTACT STRUCTURE AND METHOD FOR MANUFACTURING THE SAME

An improved wear resistant bump contact (Fig. 1, item 16) is produced by the inclusion of small particles (18) of hard materials in the conductive material of the contact bump, preferably by co-deposition at the time of electroplating of the bump bulk material. Desirable attributes of the small particles of hard material include small particle size, hardness greater than the hardness of the bulk material of the contact bump, compatibility with the plating conditions, and electrical conductivity. In one variation, the bump of metal-particle co-deposited material is coated by a thin cap layer (19) of noble, non oxidizing metal to prevent electrical erosion by arcing as contact is made and broken from the pad.
Experimental and Monte Carlo simulation on new manganese bath facility for absolute neutron source emission rate measurement at ENEA-INMRI

This work deals with the absolute measurement of the neutron emission rate from a 241Am–Be source by means of the manganese sulphate bath technique, which is the principal method for the absolute determination of the neutron emission rate from radionuclide neutron sources. The facility consists of a spherical container filled with an aqueous solution of manganese sulphate with a 241Am–Be neutron source placed at the center. As well known, neutrons from the source, after having been thermalized by the aqueous solution, undergo neutron capture by hydrogen, manganese, sulphur, and oxygen nuclei, thus inducing a certain activity to the solution. Subsequent gamma spectrometry measurements of 56Mn activity generated by 55Mn neutron activation allows to determine the neutron emission rate of the source, The experimental activity has involved a variety of measurement techniques and calculation procedures, ranging from neutron reactor activation to liquid scintillation counting and Monte Carlo calculations. Neutron activations of 55Mn samples has been carried out with the TRIGA reactor of the ENEA-Casaccia Research Centre, and 56Mn activated samples were subsequently characterized by liquid scintillation counting, in order to obtain reference standards for the calibration of the NaI(Tl) scintillation detectors utilized to record gamma-ray emission from 56Mn. Monte Carlo calculations, carried out by the MCNPX code, were required to calculate neutron transport within the sulphate manganese bath, in particular to determine 55Mn neutron capture probability, and (n, α) and (n, p) concurrent reactions, as well as the neutron leakage. Such a procedure has allowed to maintaining the neutron emission rate uncertainty well below 1 %. All the measurements have been carried out at the ENEA-Casaccia Research Centre by the Italian National Institute of Ionizing Radiation Metrology.
CONTROLLING EXHAUST GAS RECIRCULATION BY MEANS OF A LOAD SIGNAL ON AN IN-LINE INJECTION PUMP

The invention relates to an exhaust gas recirculation control system for internal combustion engines comprising an intake manifold (1) for delivering combustion air to the individual combustion chambers, an exhaust manifold (2) for discharging the exhaust gases from the combustion chambers, an exhaust gas recirculation pipe (3) that connects the intake manifold (1) and the exhaust manifold (2), and a mechanical injection pump (4) which is controlled by a control rod (5). The invention is characterized in that an electrically controlled exhaust gas recirculation valve (6) is disposed in the exhaust gas recirculation pipe (3) in order to control the effective cross section of the exhaust gas recirculation pipe (3) while an electrical tapping device (7) determines the position of the control rod (5) and then controls the exhaust gas recirculation valve (6).
[The treatment of chronic polypous rhinosinusitis in the postoperative period with low doses of clarithromycin].

The aim of this work was to study efficacy and safety of long-term low-dose clarithromycin therapy of chronic polypous rhinosinusitis during 6 months after endoscopic polyposinusotomy. 112 patients aged 25-65 yr were randomized in groups 7 days after surgery. Those in group 1 (n=66) received topic corticosteroid treatment in combination with clarithromycin (250 mg/day for 3 mo). The use of clarithromycin significantly decreased the number of clinical symptoms and improved quality of life. CT examination showed significant reduction in the frequency of relapses, episodes of acute respiratory viral infections, and their bacterial complications. All these effects persisted for 3 mo after withdrawal of clarithromycin.
NODE AND METHOD FOR AoIP ADDRESS CHANGE

A first node (110, 115, 135, 200) for an IP connection with a second node over an A interface between a Access Network (101) and a Circuit Switched Core Network (122), said IP connection comprising an RTP and an RTCP connection. The first node has an RTP address comprising an IP address and a UDP port in the RTP connection and can change its RTP address and signal said change by a message to the second node (200, 135, 110, 115) over the RTCP connection and receive an ACK message. The first node is arranged to, following said change of RTP address, receive user plane data over the RTP connection from the second node at its changed and unchanged RTP address and to initiate an Internal handover with Mobile Switching Centre support if said ACK message from the second node is not received within a time limit.
Do acoustic cues mediate host finding by Syngaster lepidus (Hymenoptera: Braconidae)?

Syngaster lepidus Brulle is a braconid solitary ectoparasitoid that attacks the larvae of the cerambycid beetles Phoracantha semipunctata and Phoracantha recurva. The beetle larvae are concealed under the bark of their Eucalyptus host trees feeding at the interface of the inner bark and the wood. Ovipositing female parasitoids search the bark surface and must first locate a host larva accurately, drill through as much as 1 cm of the bark in order to paralyze the larva beneath, and lay a single egg on the paralyzed larva. Female wasps were provided with logs infested with host larvae, in which the positions of the host larvae had been determined by X-ray imaging. The sequence of behaviors following the landing of a female wasp on an infested log was recorded on videotape and subsequently analyzed to provide a detailed description of the processes of host location and oviposition. Female wasps searched significantly more on log sections with active host larvae than inactive larvae. They also turned toward and moved in the direction of active larvae in response to sounds produced by feeding. While searching for hosts, female wasps stand on the log surface and walk towards the location of the larvae; while it is possible that they perceive both airborne sound and associated surface vibration, the vibration signals are probably more important in indicating direction and possibly distance to the host.
Early predictors of sexually intimate behaviors in an urban sample of young girls.

In recent years, concern has been raised about girls' involvement in sexual activity at progressively younger ages. Little is known about the prevalence of emerging intimate behaviors, the psychosocial factors associated with these behaviors, or the moderating effects of ethnicity on these associations in early adolescence. In the current prospective study, we examined the prevalence and predictors of sexually intimate behaviors at age 12 years in an urban community sample of 1,116 ethnically diverse girls. Cluster analysis revealed 3 groups at age 12: no sexual behavior, mild behavior (e.g., holding hands), and moderate behavior (e.g., laying together). Minority status girls reported higher rates of both mild and moderate sexually intimate behaviors compared with European American girls. After controlling for the significant effects of age 11 intimate behaviors, lifetime alcohol use, poor parent-child communication, deviant peer behavior, onset of menarche, and interactions between ethnicity and impulsivity, social self-worth and depression uniquely increased the odds of engaging in moderately intimate behaviors at age 12 years. Parenting characteristics increased the likelihood of moderate, relative to mild, behaviors. For European American girls only, high levels of impulsivity and low social self-worth were associated with a higher likelihood of engaging in moderate intimate behaviors, whereas high levels of depressive symptoms reduced the odds. The results suggest that early prevention efforts need to incorporate awareness of different social norms relating to sexual behavior.
User-side cloud service management: State-of-the-art and future directions

Abstract Cloud computing is increasing in usage because of its technical and financial advantages over traditional computing paradigms and also because of the availability of an expanding number of cloud services offered by new service providers. Consistent with its growth, there has been wide research interest in the literature that focuses on increasing cloud adoption. However, the current commercial and research-oriented cloud computing research in the literature mainly deals with functionalities closer to cloud infrastructure, such as improved performance and the management of virtualized resources, as well as fundamental issues related to efficient resource utilization, such as virtual machine (VM) migrations and server consolidation. While on the one hand, such features are very important, on the other hand, other important features, such as cloud quality of service management which is important for the cloud environment to move from a basic cloud service infrastructure to a broader cloud service ecosystem, have not received the required due attention. In cloud service management, a cloud service user has several choices for service selection and the quest to achieve interoperability and compatibility in cloud computing will consequently enable the user to easily migrate between service providers. In this scenario, the user needs to make important cloud service management decisions based on QoS, in addition to other criteria such as usage cost. These issues, when considered from a user׳s perspective, are quite different from cloud infrastructure management issues envisioned from a cloud provider׳s perspective. There are several challenges in cloud service management from a user׳s perspective, which the current cloud service management platforms in the literature do not address. To address this drawback, this paper presents a comprehensive state-of-the-art discussion on the existing approaches to cloud service management, critically evaluates them against the factors required for the user to manage the cloud service and presents a framework that assists the cloud service user in making cloud service management decisions.
Inter- and intra-individual variation of oxytocin secretion in oestrous mares exposed to stallions

The neuro-peptide hormone oxytocin regulates several reproductive mechanisms in mammals, such as uterine contractions during parturition and milk ejection in the lactating mammary gland. Oxytocin may also influence behavior and behavioral strategies, e.g. pair bonding, social recognition, maternal behavior, trust building, or anxiety. Teasing oestrous mares by a stallion provokes the release of oxytocin. We therefore tested whether such elevated oxytocin levels reveal possible mate preferences as determined in typical preference tests. Thirteen mares were tested in two consecutive oestrus cycles with two different stallions each (from a total of seven) in order to take possible individual differences into account. The mares were exposed in a teasing barn, the stallion being free in a box with a window to the outside mare. Stallions were previously determined in a t-maze preference test (preference scoring by determination of a freely moving mare’s contact time with each of two stallions positioned in the right and left boxes at the end of a stable corridor during 15 min) as preferred or non-preferred by each mare. Mares entered each trial after having been confirmed to be in oestrus by behavioral observation and transrectal ultrasonography (follicle 35 mm and uterine oedema). Testing was performed 19 hours after ovulation induction with