SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Massive formation of square array junctions dramatically alters cell shape but does not cause lens opacity in the cav1-KO mice

The wavy square array junctions are composed of truncated aquaporin-0 (AQP0) proteins typically distributed in the deep cortical and nuclear fibers in wild-type lenses. These junctions may help maintain the narrowed extracellular spaces between fiber cells to minimize light scattering. Herein, we investigate the impact of the cell shape changes, due to abnormal formation of extensive square array junctions, on the lens opacification in the caveolin-1 knockout mice. The cav1-KO and wild-type mice at age 1-22 months were used. By light microscopy examinations, cav1-KO lenses at age 1-18 months were transparent in both cortical and nuclear regions, whereas some lenses older than 18 months old exhibited nuclear cataracts. Scanning EM consistently observed the massive formation of ridge-and-valley membrane surfaces in young fibers at approximately 150 μm deep in all cav1-KO lenses studied. In contrast, the typical ridge-and-valleys were only seen in mature fibers deeper than 400 μm in wild-type lenses. The resulting extensive ridge-and-valleys dramatically altered the overall cell shape in cav1-KO lenses. Remarkably, despite dramatic shape changes, these deformed fiber cells remained intact and made close contact with their neighboring cells. By freeze-fracture TEM, ridge-and-valleys exhibited the typical orthogonal arrangement of 6.6 nm square array intramembrane particles and displayed the narrowed extracellular spaces. Immunofluorescence analysis showed that AQP0 C-terminus labeling was significantly decreased in outer cortical fibers in cav1-KO lenses. However, freeze-fracture immunogold labeling showed that the AQP0 C-terminus antibody was sparsely distributed on the wavy square array junctions, suggesting that the cleavage of AQP0 C-termini might not yet be complete. The cav1-KO lenses with nuclear cataracts showed complete cellular breakdown and large globule formation in the lens nucleus. This study suggests that despite dramatic cell shape changes, the massive formation of wavy square array junctions in intact fibers may provide additional adhesive support for maintaining the narrowed extracellular spaces that are crucial for the transparency of cav1-KO lenses.
Using 137Cs technique to quantify soil erosion and deposition rates in an agricultural catchment in the black soil region, Northeast China

article i nfo Soil erosion significantly affects the productive black soil region in Northeast China. Quantification of the soil erosion is necessary for designing efficient degradation control strategies. 137 Cs measurements undertaken on 61 sampling points collected within a 28.5 ha agricultural catchment in the black soil region of Northeast China were used to establish the magnitude and spatial pattern of soil redistribution rates as well as sediment budget within the catchment. Estimated soil redistribution rates using the Mass Balance Model 2 (MBM2) ranged from −56.8 to 171.4 t ha −1 yr −1 for the sampling points that were verified by means of both runoff plot data and pedological investigation. Erosion generally occurred behind the shelterbelts, especially in the ephemeral gully susceptibleareas, while deposition mainlyoccurred along the shelterbelts and atthe catchment outlet.Inthestudycatchment,69% oftheerodedsedimentscamefromtheslopes and31% theephemeral gullies. Sedimentsdepositedalongthe shelterbeltsatarateofca.78 t yr −1 andca.33 t yr −1 atthecatchmentoutlet.The gross soil loss rate for the catchment was −4.4 t ha −1 yr −1 with a sediment delivery ratio of 53%. The mean rate of −14.5 t ha −1 yr −1 in the erosion areas was much higher than the tolerable value, suggesting that effective soilconservationmeasuresare urgentlyrequiredtoreducethesevere black soillossforsustainable management of the soil resource.
Wise – wide instantaneous support equipment

In the aviation industry, the downtime of aircrafts due to maintenance operations, also called Aircraft On Ground (AOG), represents a huge economic loss for airline companies. Each 24 hours of AOG can cost up to 100 000$ to the company . While the repair of electronic circuits often takes only a few minutes, repairing a part of an aircraft’s structure can range from a couple of days to several weeks. The WISE (Wide Instantaneous Support Equipment) project aims at accelerating and improving structural repairs on aircrafts.

In the current market organisation, structural repairs require onsite specialized expertise. As experts are not available in every airport, they often have to be flown on site and this creates costly delays. Instead of physically moving the experts, WISE will bring expert assistance to the onsite teams through an advanced augmented reality communication system. Any maintenance site will then be able to benefit from the cumulated expertise of SUNAERO, which provides better results than any individual expert and avoids the added inconvenience of delaying the repair. Air flight security will be improved and costs reduced.

The WISE project stems from repeated requests from customers, challenging us to devise a device capable of bringing world-class expertise to their onsite general maintenance teams. As the financial and technical benefits of such a solution are quite obvious, the goal of this feasibility study is to prove that such a feat is achievable.
Directions in development

Cells in multicellular organisms organise along body and tissue axes. Cellular processes, such as division plane orientation, must be aligned with these polarity axes to generate functional 3-dimensional morphology, particularly in plants, where cell walls prevent cell migration. While some polarly localized plant proteins are known, molecular mechanisms of polarity establishment or its translation to division orientation are elusive, in part because regulators in animals and fungi appear to be missing from plant genomes. Cell polarity is first established in the embryo, but this has long been an intractable experimental model. My team has developed the genetic, cell biological and biochemical tools that now render the early Arabidopsis embryo an exquisite model for studying cell polarity and oriented division. Recent efforts already led to the unexpected identification of a novel family of deeply conserved polar plant proteins that share a structural domain with key animal polarity regulators. In the DIRNDL project, we will capitalize upon our unique position and foundational results, and use complementary approaches to discover the plant cell polarity and division orientation system. Firstly, we will address the function of the newly identified conserved polarity proteins, and determine mechanistic convergence of polarity regulators across multicellular kingdoms. Furthermore, we will use proteomic approaches to systematically identify polar proteins, and a genetic approach to identify regulators of polarity and division orientation, essential for embryogenesis. We will functionally analyse polar proteins and regulators both in Arabidopsis and the liverwort Marchantia to help prioritize conserved components, and to facilitate genetic analysis of protein function. Finally, we will use a cell-based system for engineering polarity de novo using the regulators identified in the project, and thus reveal the mechanisms that provide direction in plant development.
Améliorer la surveillance de l’infection par le ver à crochet chez les chiens en développant des tests diagnostiques rapides

Le projet vise à développer un produit innovant: tests immunochromatographiques rapides, ce qui permettra un diagnostic précoce et complet des infections des chiens avec des vers à crochet parasitaires. Des études menées jusqu’à présent ont montré qu’en plus du scintillement, les gogorijkas sont les nématodes les plus couramment trouvés chez les chiens avec une prévalence de 2 à 75 %. Ils sont aussi une menace zoonotique. Les tests rapides permettent des diagnostics de terrain, ne prenant qu’une douzaine de minutes, possibles sans l’utilisation d’équipements spécialisés et de réactifs &ndash supplémentaires; pas besoin d’effectuer des tests au laboratoire. Ils ne nécessitent pas de qualifications spécialisées de la part de l’utilisateur final, de sorte qu’ils peuvent être effectués par des vétérinaires et des éleveurs. SA.41471(2015/X) Objet de l’aide publique: art: 25 Règlement CE no 651/2014, du 17 juin 2014, déclarant certaines catégories d’aides compatibles avec le marché intérieur dans l’application des articles 107 et 108 du traité (JO L 119, p. C’est tout. UE L 187/1 du 26.06.2014)
The match/mismatch of visuo-spatial cues between acquisition and retrieval contexts influences the expression of response vs. place memory in rats

Animals can perform goal-directed tasks by using response cues or place cues. The underlying memory systems are occasionally presented as competing. Using the double-H maze test (Pol-Bodetto et al.), we trained rats for response learning and, 24 h later, tested their memory in a 60-s probe trial using a new start place. A modest shift of the start place (translation: 60-cm to the left) provided a high misleading potential, whereas a marked shift (180° rotation; shift to the opposite) provided a low misleading potential. We analyzed each rat's first arm choice (to assess response vs. place memory retrieval) and its subsequent search for the former platform location (to assess the persistence in place memory or the shift from response to place memory). After the translation, response memory-based behavior was found in more than 90% rats (24/26). After the rotation, place memory-based behavior was observed in 50% rats, the others showing response memory or failing. Rats starting to use response cues were nevertheless able to subsequently shift to place ones. A posteriori behavioral analyses showed more and longer stops in rats starting their probe trial on the basis of place (vs. response) cues. These observations qualify the idea of competing memory systems for responses and places and are compatible with that of a cooperation between both systems according to principles of match/mismatch computation (at the start of a probe trial) and of error-driven adjustment (during the ongoing probe trial).
A new process for the manufacture of methanol from waste glycerol

The idea is to bring to pre-commercial stage a highly effective, economically feasible catalyst for the conversion of glycerol (a waste product from the manufacture of biodiesel) to methanol developed under the ERC Advanced Grant – ‘After the Goldrush’ (ERC-2011-AdG-291319). ‘After the Goldrush’ is aimed at developing cheap alternatives to precious metal catalysts, particularly those containing gold and palladium that can be difficult to commercialise due to their high cost. During our initial studies which focused on finding uses for waste glycerol produced from bio-diesel manufacture. We were exploring the use of glycerol as a starting point for the synthesis of valuable compounds using redox reactions involving oxygen and hydrogen transfer reactions. Biodiesel manufacture takes triglycerides and other fatty materials that can be derived from plant or animal sources and reacts this with methanol typically in the presence of liquid sodium hydroxide. The process produces high quality biodiesel together with glycerol as a waste product. Typically on a mass basis 10 tons of biodiesel produce 1 ton of glycerol as an undesired by-product. This waste glycerol is highly contaminated with residual sodium hydroxide and unconverted fats; it represents a huge environmental problem that keeps a brake on the future expansion of biodiesel production. Hence there has been much research dedicated to finding commercially viable uses for this waste glycerol. We have discovered that this waste glycerol can be converted into methanol in the presence of water and this new reaction is the proposal we wish to bring to a proof of concept demonstration stage.
Estimating small area health-related characteristics of populations: a methodological review

Estimation of health-related characteristics at a fine local geographic level is vital for effective health promotion programmes, provision of better health services and population-specific health planning and management. Lack of a micro-dataset readily available for attributes of individuals at small areas negatively impacts the ability of local and national agencies to manage serious health issues and related risks in the community. A solution to this challenge would be to develop a method that simulates reliable small-area statistics. This paper provides a significant appraisal of the methodologies for estimating health-related characteristics of populations at geographical limited areas. Findings reveal that a range of methodologies are in use, which can be classified as three distinct set of approaches: i) indirect standardisation and individual level modelling; ii) multilevel statistical modelling; and iii) micro-simulation modelling. Although each approach has its own strengths and weaknesses, it appears that microsimulation- based spatial models have significant robustness over the other methods and also represent a more precise means of estimating health-related population characteristics over small areas.
Perioperative management of the adult scoliosis patient

Scoliosis in adults presents a uniquely different set of challenges to spine surgeons than scoliosis in the pediatric and adolescent population. The outcome of the corrective procedure in adult deformity revolves not only on meticulous surgical planning and technique but also upon optimization of a host of perioperative variables. Medical comorbidities related to advanced age are fairly common and need to be adequately controlled prior to surgery. Attenuated physiological response mechanisms to surgery-related stress in the geriatric population also require careful consideration. Anesthesia-related risk in the elderly, excessive blood loss during surgery, complications arising secondary to prolonged surgical time, the decision to stage a procedure, and maintenance of optimal nutritional status during hospitalization are the factors that play a crucial role in the perioperative management of adult spinal deformity patients. This review elaborates upon all such variables that a surgeon may come across in managing spinal deformity in the elderly and describes strategies to address them.
We value nature

The overall objective of EU-VNP-Net is to establish, support and energise an EU Valuing Nature Network of Networks (EU-VNN) and to implement a prioritised EU Valuing Nature Programme (EU-VNP) that, together, build synergies and collaborations among relevant existing and emerging networks (global, EU, national, sector, thematic, research and innovation), accelerate mainstreaming and operationalization of natural capital (NC) by businesses across the EU – in particular through uptake of NC assessment, NC accounting (NCA), nature-based solutions (NBS) and green infrastructure (GI) – and thereby contribute to the green economy and sustainable development. The EU-VNP will: (1) bring together, taking stock of and showcase relevant work being undertaken in the EU; (2) shape business perception in the EU of the value of nature as a business opportunity and as a means of reducing business risk and fostering sustainable business; (3) facilitate corporate uptake in the EU of the Natural Capital Protocol, which enables businesses to integrate NC in to business decision-making frameworks and models; (4) stimulate uptake in the EU of NCA so that businesses and their stakeholders are better aware of the value of nature in relation to business, and strengthen coherence between private and public sector work on NCA; (5) stimulate uptake in the EU of NBS, GI and related ecosystem-based solutions that enable businesses to reduce impacts and dependencies on NC and deliver benefits for both nature and business; (6) ensure that approaches adopted are optimal and scientifically rigorous; (7) explore options for a longer-term EU-VNN and/or EU-VNP beyond end of project. EU-VNP-Net will deliver impact through: (1) mainstreaming NC assessment, NCA, NBS and GI in business decision-making frameworks and models; (2) business decision-makers acknowledging the micro-and macro-economic relevance and value of NC approaches; (3) attracting private and public funding for further adoption.
TERMINAL, BASE STATION, AND WIRELESS COMMUNICATION METHOD

A terminal includes: a receiving unit which receives system information including information on a resource and/or a period for a tracking reference signal (TRS); and a control unit which controls reception of downlink control information including indication information about availability of the TRS in a resource and/or a period configured based on the system information. The control unit controls validity time of the indication information included in the downlink control information based on information about the validity time, the information being included in the system information.
Classifying Natural Waters with the Forel-Ule Colour Index System: Results, Applications, Correlations and Crowdsourcing

Societal awareness of changes in the environment and climate has grown rapidly, and there is a need to engage citizens in gathering relevant scientific information to monitor environmental changes due to recognition that citizens are a potential source of critical information. The apparent colour of natural waters is one aspect of our aquatic environment that is easy to detect and an essential complementary optical water quality indicator. Here we present the results and explore the utility of the Forel-Ule colour index (FUI) scale as a proxy for different properties of natural waters. A FUI scale is used to distinguish the apparent colours of different natural surface water masses. Correlation analysis was completed in an effort to determine the constituents of natural waters related to FUI. Strong correlations with turbidity, Secchi-disk depth, and coloured dissolved organic material suggest the FUI is a good indicator of changes related to other constituents of water. The increase in the number of tools capable of determining the FUI colours, (i) ocean colour remote sensing products; (ii) a handheld scale; and (iii) a mobile device app, make it a versatile relative measure of water quality. It has the potential to provide higher spatial and temporal resolution of data for a modernized classification of optical water quality. This FUI colour system has been favoured by several scientists in the last century because it is affordable and easy to use and provides indicative information about the colour of water and the water constituents producing that colour. It is therefore within the scope of a growing interest in the application and usefulness of basic measurement methodologies with the potential to provide timely benchmark information about the environment to the public, scientists and policymakers.
Intelligent route generation: discovery and search of correlation between shared resources

SUMMARY

Sharing information and resources on the Internet has become an important activity for education. The use of ubiquitous devices makes it possible for learning participants to be engaged in an open and connected social environment, and also allows the learning activities to be performed at any time and any place. In this study, the discovery of correlation among shared resources is concentrated. A hypothetical scenario is considered that the information, such as photos and thoughts, is applicable to be shared with implicit context (i.e., geographical information) by learners through a practical implementation, PadSCORM, on a mobile device. Two major contributions are achieved. First, the correlations among resources are determined through usage experiences mining and geographical information adjustment. It then assists learners in filtering out redundant information by highlighting the significance of resources. Second, an intelligent searching algorithm is proposed to visualize adaptive routes to facilitate search process and to enrich the learning activity. The empirical experiments revealing the feasibility and performance (e.g., accuracy and effectiveness) are conducted in the universities in North Taiwan. Copyright © 2012 John Wiley & Sons, Ltd.
Online joint palmprint and palmvein verification

As a unique and reliable biometric characteristic, palmprint verification has achieved a great success. However, palmprint alone may not be able to meet the increasing demand of highly accurate and robust biometric systems. Recently, palmvein, which refers to the palm feature under near-infrared spectrum, has been attracting much research interest. Since palmprint and palmvein can be captured simultaneously by using specially designed devices, the joint use of palmprint and palmvein features can effectively increase the accuracy, robustness and anti-spoof capability of palm based biometric techniques. This paper presents an online personal verification system by fusing palmprint and palmvein inforA fast palmprint and palmvein recognition systemA fast palmprint and palmvein recognition system quality can vary much, a dynamic fusion scheme which is adaptive to image quality is developed. To increase the anti-spoof capability of the system, a liveness detection method based on the image property is proposed. A comprehensive database of palmprint-palmvein images was established to verify the proposed system, and the experimental results demonstrated that since palmprint and palmvein contain complementary information, much higher accuracy could be achieved by fusing them than using only one of them. In addition, the whole verification procedure can be completed in 1.2s, which implies that the system can work in real time.
Enhancement of training capabilities in vver technology through establishment of vver training academy (corona ii)

The main objective of the proposed CORONA II project is to enhance the safety of nuclear installations through further improvement of the training capabilities aimed at building up the necessary personnel competencies.
Specific objective of the proposed CORONA II project is to proceed with the development of state-of-the-art regional training center for VVER competence (which will be called CORONA Academy), whose pilot implementation through CORONA project (2011-2014) proved to be viable solution for supporting transnational mobility and lifelong learning amongst VVER operating countries. The project aims at continuation of the European cooperation and support in the area for preservation and further development of expertise in the nuclear field by improvement of higher education and training. This objective will be realized through networking between universities, research organisations, regulatory bodies, industry and any other organisations involved in the application of nuclear science, ionising radiation and nuclear safety.
The proposed CORONA Academy will maintain the nuclear expertise by gathering the existing and generating new knowledge in the VVER area. It will bring together the most experienced trainers in the different aspects of the area within EU and abroad, thus overcoming the mobility challenge that stands ahead the nuclear education and training community. The selected form of the CORONA Academy, together with the online availability of the training opportunities will allow trainees from different locations to access the needed knowledge on demand. The available set of courses will cover the whole range of training of VVER specialists from the university until reaching high professional skills and competences in the area.