SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Magneto-vortical evolution of QGP in heavy ion collisions

The interplay of magnetic field and thermal vorticity in a relativistic ideal fluid might generate fluid vorticity during the fluid evolution provided the flow fields and the entropy density of the fluid is inhomogeneous \cite{Mahajan:2010}. Exploiting this fact and assuming large magnetic Reynolds number we study the evolution of generalised magnetic field ($\hat{B}$) which is defined as a combination of the usual magnetic field ($\vec{B}$) and relativistic thermal vorticity ($\omega^{\mu\nu}$), in a 2(space)+1(time) dimensional isentropic evolution of Quark Gluon Plasma (QGP) with longitudinal boost invariance. The temporal evolution of $\hat{B}$ is found to be different than $\vec{B}$ , and the $\hat{B}$ evolution also depends on the position of the fluid along the beam direction (taken along the z axis) with respect to the mid-plane $z=0$. Further it is observed that the transverse components ($\hat{B_{x}}$, $\hat{B_{y}}$) evolve differently around the mid-plane.
One step modification of space-integrated systems

The European Space Sector is facing an imminent crisis. Metal adhesive bonding is a critical process for fabricating satellites and it relies heavily on a toxic metal priming process called chromate conversion coating. Environmental legislation (REACH) will prevent the use of the commonly used chromate conversion coatings due to their hazardous nature with sunset dates in 2017 and 2019 for corrosion and primer treatments respectively. Potential replacements may only give a short reprieve from regulation restriction as they are all based on a wet-chemistry approach that is fundamentally tied to the use of aggressive chemicals. Although not currently under REACH regulation, these chemicals are listed as substances of very high concern (SVHC). 

The OSMOSIS project aims to utilise the ENBIO patented CoBlast process as a new surface adhesion primer solution. It uses no hazardous chemicals and meets or exceeds existing industry standard performance. CoBlast is already used by ENBIO to apply a qualified thermal control coating for the European Space Agency for spacecraft. The process is highly flexible and can be altered to apply an adhesive primer to replace chromate conversion. The CoBlast adhesive priming process has already passed testing in the automotive sector and is at TRL 6. 

The key goal of this project, OSMOSIS, is to bring this adhesive primer solution through full commercialisation within the European Space Sector. Utilising the SME Instrument Phase 2 program enables ENBIO to accelerate their route to market within the 2 year project duration, which would be projected to take up to 5 years without this support. Space Sector adhesion applications have a relatively low process throughput time requirement and very defined part geometries. Once the process has been scaled for the Space sector, it can then be further scaled as a proven technology into the Aerospace and Automotive sectors where they have an identical problem but require faster processing times.
Is prodrug design an approach to increase water solubility?

Water solubility has been identified as a critical parameter and the main responsible by affecting poor performance of oral drug delivery. Poorly soluble drugs can originate unsatisfactory ADME properties leading to low oral bioavailability, insufficient chemical stability, low half-life, fast pre-systemic metabolism and difficulties in formulation. In this context, the prodrug design is an alternative in order to improve physicochemical, biopharmaceutical and pharmacokinetic properties such as permeability, solubility, bioavailability, chemical stability and metabolism of molecules presenting poor drug-like properties. In this article we highlight the importance of the prodrug design in the early stages of drug discovery and development process, in an attempt to diminish the attrition rate and end up falling into the valley of death. Selected examples of this strategy are provided in this review and they are classified by some basic functional groups that are amenable to the prodrug approach with the aim of increasing aqueous solubility of poorly water-soluble compounds. Over the past decade, the number of approved prodrugs is considerable among all drugs launched in the market, emphasizing the importance of this tool on drug design. It is reported that 10% of all marketed drug worldwide can be classified as prodrugs. Furthermore, prodrugs designed to be more water soluble launched in the past decade are summarized in a table to have a closer look and finally state that the prodrug design is an amenable approach to increase water solubility.
A novel universal influenza vaccine targeting epitopes of limited variability

The antigenic evolution of influenza is conventionally assumed to occur by ‘antigenic drift’ where new strains arise through the incremental addition of mutations in surface glycoproteins. However, the antigenic drift model can only explain the epidemiology and limited genetic diversity observed among influenza virus populations by imposing constraints on the mode and tempo of mutation. We have shown that an alternative model known as ‘antigenic thrift’ successfully models the epidemiology and genetic diversity of influenza by assuming that the antigenic evolution of the virus population is primarily driven by natural immune responses against epitopes of limited variability.   We have identified epitopes of limited variability in H1, H3 and influenza B. Each epitope has between 3 and 4 different conformations. These epitope conformations are all in the head domain of the HAs of various subtypes, making them naturally highly immunogenic. The epitope are also limited in variability, often due to their position adjacent to the receptor binding site, cycling through their limited repertoire of conformations as host population immunity changes.    By vaccinating against these epitope conformations for each subtype, we can induce immunity against all past and present H1, H3 and influenza B. This approach will remove the need to vaccinate each year and have much higher levels of efficacy. The vaccine can also be made using the established methods of inactivated or attenuated influenza vaccine production. This maintains a price threshold of 5 USD per dose, making the vaccine attractive to pharmaceutical companies, and by reducing the number of doses required to confer immunity and while maintaining production cost, the vaccine is attractive to healthcare providers.
Comparison of MRI, F-18 FDG, and 11C-Choline PET/CT for Their Potentials in Differentiating Brain Tumor Recurrence From Brain Tumor Necrosis Following Radiotherapy

To compare potentials of magnetic resonance imaging (MRI), F-18 FDG, and 11C-Choline PET/CT in differentiating brain tumor recurrence from necrosis after radiotherapy.Fifty-five patients with suspected brain tumor recurrence or necrosis after radiotherapy underwent MRI, F-18 FDG, and 11C-choline PET/CT examinations, and all the patients were followed up for at least 11 months. Lesion diagnoses based on medical imaging were compared with pathology or follow-up outcomes.The sensitivities of MRI, F-18 FDG PET/CT, and 11C-Choline PET/CT in lesion diagnosis were 87.2%, 76.9%, and 92.3%, respectively, and their specificities were 81.3%, 62.5%, and 87.5%, respectively.The results suggest that 11C-Choline PET/CT with higher sensitivity and specificity may be better in distinguishing recurrent brain tumor from radionecrosis compared with F-18 FDG PET/CT and MRI.
Genotoxicity prediction by means of qsar methods for regulatory purposes

The concern to protect human health and the environment has prompted significant changes in EU regulation on chemical
substances. The European Chemicals Agency (ECHA) plays the role in implementing the Registration, Evaluation,
Authorization and Restriction of Chemicals (REACH) legislation, that requires industry to evaluate the toxicity of chemical
substances that are in use but have never been subjected to regulatory testing.

REACH regulation has also raised strong criticism and concern from society and industrials because of ethical and economic
reasons. The toxicity evaluation of chemicals requires costly, time-consuming and ethically questionable animal
experiments. As consequence, this European regulation promotes scientific innovation and encourages the use of results
generated by alternative methods, including especially non-testing methods (NTMs), also referred to as in silico tools.

Among them, “Quantitative Structure-Activity Relationships” (QSAR) methods are one of the most recognized machine
learning methods in drug design, toxicology, industrial and environmental chemistry. Nowadays, they can be included in
integrated testing strategies (ITS), to provide information for hazard and risk assessment, classification and labelling.

We propose the development of an ensemble of QSAR predictive models for several parameters related with the different
kinds of genotoxicity damage. These chemoinformatic will be implemented on a proprietary computational technological
platform. Particular attention will be also payed to the generation of models for nanomaterials, taking into account their high
and growing impact nowadays on industry in general.The QSAR models and integration algorithms will be characterized by
their reliability, and will be developed according to the rules set out by the OECD, therefore guaranteeing their validity in
REACH.
INKJET PRINTING METHODS FOR MANUFACTURING DECORATIVE LAMINATE PANELS

An inkjet printing method for manufacturing decorative laminate panels ordered by a customer including the steps of: i) providing an inkjet printing device with a print job including one or more decorative patterns and an identification code assigned to the one or more decorative patterns; and ii) printing the one or more decorative patterns with one or more inkjet inks and applying the identification code on a substrate web, wherein the substrate web is a paper substrate and the one or more inkjet inks are aqueous pigmented inkjet inks are printed on the substrate web before impregnation with a thermosetting resin; or wherein the one or more inkjet inks are UV curable inkjet inks and the substrate web is a thermoplastic substrate web based on a material selected from the group consisting of polyvinylchloride (PVC), polypropylene (PP), polyethylene (PE), polyethylene-terephthalate (PET) and thermoplastic polyurethane (TPU).
Engineering chemotactic biosensors for a diverse spectrum of metastatic markers

Directional movement of cells in response to environmental cues (e.g. chemotaxis) is essential throughout biology, and the membrane receptors that initiate cell migration offer a key opportunity for modulation by synthetic biologists. The design of chemotactic receptor biosensors for metastatic markers has the potential to expand the immune system’s spectrum of actions. Metastatic cancers are extremely lethal, and tumor cells that escape to seed a secondary tumor in a distant organ often escape immunosurveillance. Extensive studies on metastasis have identified soluble secreted factors that promote the initial escape of tumor cells, their intravasation into circulation, and extravasation into metastatic niches where they can proliferate and form new malignant tumors. We will employ a host of computational design techniques developed in the Barth Lab to build novel biosensors that will elicit chemotactic responses towards molecular indicators of metastatic cells at various key points during their journey to secondary sites when they are vulnerable to engineered cytotoxic immune (T and NK) cells. By harnessing the migratory potency of a chemokine receptor scaffold, we will design several novel chemotactic receptors sensing molecules of increasing complexity to ultimately build and validate a general computation-based platform for rational biosensor design. At a fundamental level, engineering membrane receptors that can respond to a diversity of molecules is a stringent test of our biophysical understanding of protein structure and function, but also has far-reaching applications in basic and translational research with immediate relevance and impact for cancer therapeutics.
METHOD FOR PRODUCING AN ELECTROCHEMICAL ENERGY STORAGE CELL, ENERGY STORAGE CELL, BATTERY MODULE AND VEHICLE

The invention relates to a method for producing an electrochemical energy storage cell, to an electrochemical energy storage cell, to a battery module and to a vehicle. The electrochemical energy storage cell has a housing, a pressure sensor which is arranged in the housing and is configured to sense a pressure, and to generate a corresponding sensor signal, and a data storage device which is arranged in the housing and in which a characteristic curve of the pressure sensor is stored, wherein the characteristic curve of the pressure sensor specifies a relationship between, on the one hand, at least one sensor signal generated by the pressure sensor during the sensing of at least a pressure within the housing and, on the other hand, the pressure value of the at least one pressure within the housing.
Geologically Controlled Coastal Systems: Rocky Coasts, Bluffs, Cliffs and Shore Platforms

Most of the world’s coasts develop in hard or cohesive materials typical of mountainous continental margins. Indeed, since the work of (Emery and Kuhn in Geol Soc Am Bull 93:644–654, 1982), the literature has commonly reported that 80% of the world’s coasts can be categorized as rocky or cliffs. However, these coasts do not usually appear in our minds when we imagine a coast. This happens because humans normally settle their resorts on low coasts associated with depositional systems and usually keep them away from steep coasts. The scarcity of research work on these rocky coastal systems does not help to favor them as well-known coasts either. In recent decades, these environments have attracted less attention than other systems located on coastal plains that are more vulnerable to problems associated with global change. However, rocky coasts offer very beautiful panoramas and spectacular views of processes, especially during storms, and play an important role as a supplier of sediments to depositional environments.
OWA Operators in Regression Problems

We consider an application of fuzzy logic connectives to statistical regression. We replace the standard least squares, least absolute deviation, and maximum likelihood criteria with an ordered weighted averaging (OWA) function of the residuals. Depending on the choice of the weights, we obtain the standard regression problems, high-breakdown robust methods (least median, least trimmed squares, and trimmed likelihood methods), as well as new formulations. We present various approaches to numerical solution of such regression problems. OWA-based regression is particularly useful in the presence of outliers, and we illustrate the performance of the new methods on several instances of linear regression problems with multiple outliers.
PAPER MADE WITH CELLULOSE FIBERS HAVING AN INNER CORE OF CELLULOSE ACETATE

A composition of paper comprising 99 to 10 weight percent cellulose fibers and 1 to 90 weight percent cored cellulose fibers that are uniformly dispersed within the paper. The cored cellulose fibers are composed of a cellulose sheath that is 4 to 15 weight percent of the weight of the fiber and a cellulose acetate core. The cored cellulose fibers contain no substantial crimp and have an average length of 1 to 7 mm, a density of 1.20 to 1.35 gm/cc, a denier 1 to 30 grams per 9,000 meters and a uniform dispersion index of less than 0.15.
Marcadores serológicos asociados a mal pronóstico en pacientes Covid-19 positivos

Antecedentes: Covid-19 es una enfermedad causada por un nuevo coronavirus conocido como SARS-CoV-2. La proteína viral Spike se une a los receptores corporales ACE2 y determina su infectividad. Este proceso tiene muchos efectos en el huésped, causando daños en el sistema respiratorio y a nivel sistémico en general, evidenciados en la elevación de marcadores de laboratorio como la Interleucina-6, Ferritina y D-Dímero. Objetivo: Analizar los biomarcadores (Interleuquina-6, Ferritina y D-Dímero) como factores de mal pronóstico en Covid-19.Métodos: Se recolectaron los datos de los pacientes con Covid-19 que además tenían resultados de IL-6, D-D y Ferritina obtenidos a través de las bases de datos del hospital IESS Ambato.Resultados: Reportamos 114 pacientes con Covid-19, a quienes analizamos los marcadores serológicos. D-D e IL-6 muestran una OR de 1,34 (C.I.: 1,14 - 1,58) y 1,26 (C.I.: 1,11 - 1,43) respectivamente. La ferritina tuvo una asociación positiva en la población femenina 1,11 OR (C.I.: 0,99 - 1,24), pero en la población masculina, no encontramos una asociación significativa 3,91 OR (C.I.: 0,46 - 32,99). Se encontró que las comorbilidades eran un factor protector con una asociación negativa de OR = 0,88. Las causas secundarias de muerte en los pacientes Covid-19 fueron la parada cardiaca y la neumonía (23,1%).Conclusiones: Los marcadores IL-6, Ferritina y D-D fueron evaluados y demostraron ser herramientas valiosas para predecir el mal pronóstico en pacientes con Covid-19. Estos marcadores procedieron independientemente de otros factores como las comorbilidades. Los hallazgos de este estudio pueden ayudar al manejo y pronóstico.
LAUNDRY DETERGENT CONTAINING A POLYHYDROXY FATTY AMIDE AND INSOLUBLE ETHOXYLATED ALCOHOL.

Compositions détergentes pour blanchissage comprenant un ou plusieurs agents tensio-actifs anioniques, cationiques, ampholytiques ou zwitterioniques solubles dans l'eau ou leurs mélanges et une combinaison des éléments suivants: (a) au moins 1 % en poids de la composition d'un amide d'acide gras polyhydroxy de formule (I) où R1 est H, un hydrocarbyle C1-C4, de l'éthyle 2-hydroxy, du propyl 2-hydroxy ou leurs mélanges, R2 est un hydrocarbyle C5-C31, et Z est un polyhydroxyhydrocarbyle dont la chaîne hydrocarbyle linéaire comprend au moins 3 groupes hydroxy directement reliés à la chaîne, ou un dérivé alkoxylé de ce polyhydroxyhydrocarbyle; (b) au moins 1 % en poids de la composition d'un alcool aliphatique primaire éthoxylé C11-C15 pratiquement insoluble dans l'eau contenant en moyenne au plus 5 groupes oxyde éthylène par mole et d'une teneur en oxyde d'éthylène inférieur à 50 % en poids. Les agents tensio-actifs solubles dans l'eau sont de préférence des agents tensio-actifs anioniques, ou mieux encore des compositions d'agents tensio-actifs sans alkyle, ni benzène, ni sulfonate.
A Novel Intelligent Water Drops Optimization Approach for Estimating Global Solar Radiation

Measurement of the solar radiance requires utilization of expensive devices. To address this issue, estimator models are used to facilitate the measurement process. In this paper, a new method based on the empirical equations is introduced to estimate the monthly average of daily global solar radiation on a horizontal surface. The proposed method takes advantages of an intelligent water drops algorithm as a swarm-based nature-inspired optimization technique. This algorithm has been implemented in the MATLAB software. The best obtained coefficients of linear and nonlinear empirical models and global solar radiation are employed for the measurement of the six different climate regions of Iran. Performance of this approach has been compared to the other existing techniques. The result reveals the superiority of the proposed method in term of accuracy for estimating the monthly average daily global solar radiation.
Development of healthy host-microbial mutualism in early life

Background
Humans and other animals harbour enormous microbial consortia, especially in the lower intestine. My group has now shown that effects of the microbiota on host are far earlier and more pervasive than previously appreciated, starting even before birth from exposure to defined maternal microbial metabolites.
Concept
There is a critical window for development of immunity and metabolism in early life. This shapes infectious resistance, lymphocyte repertoire development and the likelihood of later autoimmune or inflammatory disease. We will determine the molecular mechanisms of how the maternal microbiota prepares the newborn for the critical fetal/suckling/early-independent-nutrition transitions. The core hypothesis is that generally pervasive effects of maternal microbial influences, so-far investigated only for innate immunity and metabolism of germ-free offspring, can be defined in terms of a clear portfolio of maternal microbial molecular signatures and epigenetic marks as the newborn develops with its own microbiota.  
Approach
Interdependence of microbial ⇄ host interactions during gestation and lactation will be dissected using reversible colonisation systems under axenic and precisely controlled gnotobiotic conditions. The flow and identity of maternal microbial metabolites driving development and shaping incoming colonisation shall be determined from high-resolution metabolomics and host strain combinations that reveal in vivo signalling and epigenetic marks. 
Significance
The project will reveal mechanisms of the earliest phases of mammalian adaptation to a microbiota, the epigenetic effects of maternal microbial metabolites and the resulting potential protection from metabolic disease or immunopathology. Conversely, there are profound effects of early life adaptation on the dynamics of microbial colonisation and the potential blooms and extinctions for the incoming microbiota: the project will define the different mechanisms involved.
Lignolytic Enzymes Production from Selected Mushrooms

In this paper, ligninase enzymes produced by selected mushrooms have been reported. We collected mushrooms from Western Ghats, most of them were edible food. Thirty samples isolated were tested using a plate assay through direct agar plate assay by using ABTS, decolourisation containing the fifteen isolates were able to decolourise the dye, indicating a lignin-degrading ability. Spectrophotometric enzyme assays from all selected isolates were carried out to examine the production of Ligninolytic enzymes (Laccase, lignin peroxidase and manganese peroxidase). Ten selected isolates produced all three kinds of enzymes tested. Lignolytic enzymes are groups of enzymes these are actively involved in bioremediation.Int J Appl Sci Biotechnol, Vol 3(2): 308-313 DOI: http://dx.doi.org/10.3126/ijasbt.v3i2.12732
Variable pressure fuel generator and method

A method and apparatus for generating acetylene gas by reacting water and calcium carbide wherein a tank containing water is pressurized by a pump in a manner feeding the water to another vessel wherein it reacts with particulate calcium carbide to generate acetylene gas. A portion of the acetylene gas is returned through a pressure regulator to the water tank in a manner maintaining regulated system operating pressure on the water to sustain the reaction without overproduction of the gas. The apparatus can be located in a vehicle for on board generation of acetylene gas as fuel for the internal combustion engine thereof.
SYSTEMS AND METHODS FOR WIRELESS DISPLAY DISCOVERY

The present disclosure relates to computer-implemented systems and methods for wireless display discovery. The method may include receiving, by a computer, a selection to detect wireless display devices. The computer may include one or more processors, a radio transceiver, and a microphone. The method may also include identifying, by the radio transceiver, a plurality of wireless display devices and transmitting, by the radio transceiver, respective connection requests to the plurality of wireless display devices. Additionally, the method may include transmitting, by the radio transceiver to the wireless display devices, respective requests for inaudible audio signal transmission. The method may also include receiving, by the microphone, a plurality of inaudible audio signals from the wireless display devices. Further still, the method may include determining, based at least in part on the plurality of inaudible audio signals, whether any of the plurality of wireless display devices are in the same room as the computer.