SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Multi object spectrometer with an array of superconducting integrated circuits

Recent sub-millimeter instruments on the Herschel Space Observatory, operational from 2009-2013, have discovered thousands of sub-millimeter galaxies, whose combined emission forms the cosmic infrared background. A major challenge is to measure their distance, or age, by determining their redshifts, which also has to be based on the sub-millimeter signals (because they do not have an optical counterpart).  

I propose to develop a new redshift survey instrument, using recent progress in superconducting nanotechnology, which can spectrally resolve a large fraction of the cosmic infrared background from the ground. The instrument is a Multi-Object Spectrometer with an Array of superconducting Integrated Circuits. It consists of a 3D integrated field spectrograph with a 2D array of 25 pixels sparsely filling the re-imaged focal plane of the observatory. For each pixel the instrument measures the radiation spectrum in a 325-905 GHz window with a resolution R=F/δF=500. Additionally the beam of each pixel can be steered electrically to lock onto an individual astronomical object. This allows fast, high accuracy redshift determination of 25 objects simultaneously by measuring the frequency shift of the CII and CO lines. I will develop the instrument, build it, install it on the 10 m Japanese ASTE observatory in Chile and facilitate its use.

MOSAIC will be fully based on novel superconducting circuits: a broad-band antenna with electrical beam steering and an on-chip spectrometer, combined on a single chip. The design of the instrument is based on recent developments in superconducting nanotechnology, for signals in the GHz to THz range, in which I am currently playing a leading role. The instrument will be developed with a team of experts in the fields of antennas, spectrometer and readout electronics.
Decision Making and its Positive Approach

The choice sciences and care hypothesis both concentrate on consideration regarding perspectives and their roots. Truly, these two models of investigating thought have, notwithstanding, wandered. Research and hypothesis in the choice sciences have concentrated on the comprehension of inclinations, heuristics, and what some may call botches, in choice making. In the choice sciences, endeavors have been gone for highlighting the impact of these oversights, and on exhibiting imperfect discernments so as to show the requirement for more reactions to jolts. While the choice sciences give profitable data about the routes in which individuals make imperative, and not all that critical, decisions, endeavors to diminish the impacts of predispositions on choice making have had blended results, and little is presently thought about how to enhance choice making results notwithstanding inclinations [1].
Curable fluorosilicone rubber composition

A room temperature-curable fluorosilicone rubber composition is disclosed, which is capable of giving a cured silicone rubber having excellent resistance against organic solvents and petroleums withhigh curability despite the high fluorine content which may cause steric hindfrance against the curing reaction due to the bulkiness of the fluorine-containing substituent groups. Different from conventional fluorine-containing diorganopolysiloxanes, in which the fluorine-containing substituent groups are bonded to the silicon atoms at random positions throughout the molecule, several silicon atoms from each of the molecular chain ends of the diorganopolysiloxane as the principal ingredient of the inventive composition are free from fluorine-containing substituent groups so that the crosslinking reaction with the silanolic hydroxy groups bonded to the terminal silicon atoms is not disturbed by the fluorine-containing groups in the vicinity of the terminal silanol groups.
20 anos de presença no Brasil

Em 2021 a Revista Memorandum alcançou o marco de 20 anos de publicação ininterrupta, difundindo no país pesquisas do campo da fenomenologia, memória, história e religião. No mesmo ano, celebramos também 20 anos do início da parceria da filósofa italiana Angela Ales Bello com pesquisadores brasileiros. Como um brinde à dupla comemoração, discutimos neste texto a originalidade da fenomenologia clássica e suas contribuições para as ciências em geral e, em particular, para a psicologia, psicopatologia e estudo das religiões. Também é realizado um resgate de memórias sobre o início do intercâmbio com pesquisadores brasileiros que contribuiu a um só tempo para o desenvolvimento da psicologia fenomenológica no país e para a consolidação da revista Memorandum como periódico de referência nesta área.
Silver supported on hierarchically porous SiO2 and Co3O4 monoliths: Efficient heterogeneous catalyst for oxidation of cyclohexene

Abstract This study describes silver (Ag) nanoparticles supported on hierarchically porous SiO 2 and Co 3 O 4 monoliths and the use of these materials as heterogeneous catalysts for the oxidation of cyclohexene. Structural characterization of these materials was carried out by various techniques including scanning electron microscopy (SEM), N 2 adsorption, X-ray diffraction (XRD), and X-ray photoelectron spectroscopy (XPS). Characterization results revealed that Ag nanoparticles were incorporated into hierarchically porous SiO 2 and Co 3 O 4 without significantly affecting the structures of the supports. The oxidation of cyclohexene was investigated for hierarchically porous Ag/SiO 2 and Ag/Co 3 O 4 monoliths and powdered forms of the catalysts using H 2 O 2 as oxidant. Detailed parameters including the effect of temperature, oxidant, catalyst loading, and substrate to oxidant ratio were thoroughly studied. The catalyst was found to be stable and could be reused several times without affecting its catalytic activity under the optimized reaction conditions.
Significant Increase in 1-Year Posttransplant Renal Arterial Index Predicts Graft Loss

Conflicting data have been reported concerning the use of kidney graft arterial resistance index (RI) measured by Doppler to predict death-censored graft loss. We hypothesized that changes in RI values could carry better information than a single measure of RI.Four hundred twenty-five renal transplant recipients were included in the study. We tested whether changes in renal arterial resistance index between 4 and 12 months after transplant (ΔRI(4→12)) were predictive of graft loss.Neither 4-month nor 1-year RI predicted graft loss. The area under the receiver operating characteristics curve of ΔRI(4→12) for graft loss was 0.75. A ΔRI(4→12) ≥10% had the best sensitivity and specificity. One year after transplant, 22% of the study population had ΔRI(4→12) ≥10%. Fifty-five patients (12.9%) experienced graft loss during follow-up. The annual incidence of graft loss was higher in patients with ΔRI(4→12) ≥10% (3.5 versus 1.3%; P = 0.009). In multivariate analysis, patients with ΔRI(4→12) ≥10% had an increased risk of graft loss (hazard ratio, 6.21; 95% confidence interval, 1.99 to 22.15; P = 0.002).A variation in RI ≥10% in the first year after transplant is an independent risk factor for death-censored graft loss in renal transplant recipients.
Local congregations: Engaging neighbors of other faiths

When I was growing up in rural north Georgia in the 1950s and 60s, religious diversity meant there might be a Pentecostal church tucked in among the Baptist and Methodist churches. Today, congregations typically do not live in communities in which religious diversity is so narrowly experienced. Diversity no longer even signals that there are Protestant, Pentecostal, Catholic, and Jewish houses of worship present. The increase in the scope of diversity in almost every community means there are representatives of various non-Abrahamic religions present as well. Members of these different faith expressions live together in community, send their children to the same public schools, participate in local civic events, and serve one another as physicians, pharmacists, teachers, restauranteurs, hoteliers, and retailers. In short, people of diverse religions live, work, and worship in close proximity. How, then, do they form community in which the social fabric of the city, county, or state in which they live, and ultimately that of the nation, is strengthened by a commitment to the common good that secures for all the blessings of security, peace, and justice? In this multi-religious context, how are Christian congregations enhancing rather than hindering the building of community in diversity?
Oncocin Onc72 is efficacious against antibiotic-susceptibleKlebsiella pneumoniaeATCC 43816 in a murine thigh infection model

Oncocins and apidaecins are short proline-rich antimicrobial peptides (PrAMPs) representing novel antibiotic drug lead compounds that kill bacteria after internalization and inhibition of intracellular targets (e.g. 70S ribosome and DnaK). Oncocin Onc72 is highly active against Gram-negative bacteria in vitro and in vivo protecting mice in systemic infection models with Escherichia coli and KPC-producing Klebsiella pneumoniae. Here we studied its efficacy in a murine thigh infection model using meropenem as antibiotic comparator that had a 44-fold higher molar in vitro activity than Onc72. Male CD1 mice were rendered neutropenic using cyclophosphamide for four days before intramuscular infection with K. pneumoniae ATCC 43816. After 75 min oncocin Onc72 or the antibiotic comparator meropenem were administered subcutaneously with 100 mg (43 µmol) and 25 mg (65 µmol) per kg of body weight, respectively, six times every 75 min. Onc72 and meropenem administered subcutaneously reduced the thigh tissue burden of K. pneumoniae ATCC 43816 in neutropenic mice significantly by 4.14 and 4.65 a log10 cfu/g, respectively. The bacterial counts were ∼0.5 and ∼1 log10 below the pre-treatment burden, respectively, indicating bactericidal effects for both compounds. Thus, Onc72 was as efficacious as meropenem in vivo despite its much lower in vitro activity determined according to CLSI standard antimicrobial activity tests.
Simulation of three-dimensional CFD of water flow at pyramid artificial reef

Three-dimensional water flow fields at a pyramid artificial reef with three meters high and three meters long of each side of the base were numerically simulated using CFD approach under the five different incoming velocities(0.1,0.2,0.4,0.6 and 0.8 meter per second respectively).The maximum upwelling height,the maximum and average velocities of the upwelling current as well as the size of wake vortex region were all obtained quantitatively.The paper revealed the characteristics of distributions of vorticity and pressure around the pyramid reef and obtained the hydrodynamic forces and drag coefficients.Moreover,it compared the discrepancies of pyramid reef with a rectangular reef and a three prism reef in the quantitative characteristic of upwelling and wake vortex region current.
Limeron

Le Centre estonien de recherche sur la tourbe a été créé en tant que spin-off de l’Université de Tartu en 2014 et son principal objectif est de créer des produits à forte valeur ajoutée à base de tourbe et d’autres matières premières locales. Un matériau de construction unique a été créé, le limeron (nom préliminaire) à base de matières premières locales (peuples, etc.) et de déchets (crêne de roche, polymères réutilisables). Le matériau peut être utilisé comme matériau d’isolation, pour les constructions de bâtiments et pour l’impression 3D de bâtiments entiers.
N-CYCLYL-3 - (CYCLYLCARBONYLAMINOMETHYL) BENZAMIDE DERIVATIVES AS RHO KINASE INHIBITORS

The present invention relates to compounds of formula (I) : and pharmaceutically acceptable salts thereof, wherein R1and R2 are various ring systems. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of Rho Kinase mediated diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.
Wave-Modulated arctic air-sea exchanges and turbulence

Wave-modulated Arctic Air-sea eXchanges and Turbulence (WAAXT) is a project designed to improve our understanding of ocean boundary layer processes in a changing Arctic Ocean.  Sea ice extent in the Arctic Ocean has been decreasing since the beginning of the satellite era, meaning that open-water, as opposed to under-ice, oceanographic processes are becoming increasingly important for Arctic dynamics.  One of the most fundamental differences between the open and ice-covered oceans is the presence of surface waves.  Surface waves and wave-driven processes drastically alter air-sea fluxes, upper-ocean turbulence, and the dominant dynamical balance in the upper ocean.  

WAAXT will be based on a series of field experiments to study the small-scale processes associated with this emerging wave climate, with a particular focus on near-surface turbulence.  Three major effects of wave processes will be targeted: 1) Modification and suppression of ice formation by wave motions and the associated elevated near-surface turbulence.  2) Physical breakup of sea ice by wave motions, and the associated contributions to the modification of air-sea fluxes, upper-ocean structure, and melt rates.  3) Interactions between wave-driven turbulence, especially breaking and Langmuir circulations, with the unique salinity-based stratification in the Arctic basin.  A key aspect of these processes is their horizontal variability, which will be captured using a multi-platform approach.  Experimental work will begin in a natural laboratory in the Saint Lawrence Estuary and move to the Arctic as scientific and technical capacity is developed.

The long-term goal for WAAXT is to produce the data and parameterizations needed to understand climate-scale feedbacks associated with the emerging wave climate in the Arctic basin.
PROCESS FOR THE TOTAL CONVERSION OF HEAVY FEEDSTOCKS TO DISTILLATES

Process for the conversion of heavy feedstocks comprising the following steps: mixing the heavy feedstock with a suitable hydrogenation catalyst and sending the mixture obtained to a first hydrotreatment area (HT1) to which hydrogen or a mixture of hydrogen and H2S are introduced; sending the effluent stream from the first hydrotreatment area (HT1), containing the hydrotreatment reaction product and the catalyst in dispersed phase, to a first distillation area (D1) having one or more flash steps and/or atmospheric distillation and/or vacuum distillation whereby the various fractions coming from the hydrotreatment reaction are separated; sending at least part of the distillation residue (tar) or liquid leaving the flash unit of the first distillation area (D1), containing the catalyst in dispersed phase, rich in metalic sulfides produced by demetallation of the feedstock and optionally minimum quantities of coke, to a deasphalting area (SDA) in the presence of solvents or to a physical separation area, obtaining, in the case of the deasphalting area, two streams, one consisting of deasphalted oil (DAO), the other containing asphaltenes at least partially recycled to the first hydrotreatment area, in the case of the physical separation area, the solids separated and a liquid stream,- sending the stream consisting of deasphalted oil (DAO) or the liquid stream separated in the physical separation area to a second hydrotreatment area (HT2), to which hydrogen or a mixture of hydrogen and H2S and a suitable hydrogenation catalyst are introduced; sending the effluent stream from the second hydrotreatment area (HT2), containing the hydrotreatment reaction product and the catalyst in dispersed phase, to a second distillation area (D2) having one or more flash and/or distillation steps whereby the various fractions coming from the second hydrotreatment area are separated; recycling at least part of the distillation residue or liquid leaving the flash unit of the second distillation area (D2), containing the catalyst in dispersed phase to the second hydrotreatment area (HT2).
Effect of Reaction Temperature in the Alumina Preparation by Combustion in a Muffle Furnace

The aim of this study is to evaluate the effect of temperature during the synthesis of alumina by combustion in a muffle furnace. The alumina was characterized by X-ray diffraction, particles size distribution and scanning electron microscopy. The results showed that the synthesis temperature of the alumina can affect the structure of the produced samples. The size distribution of the median particle diameter reached higher value for the alumina synthesized at 500°C with 16.07 μm, the range of the total distribution of particles is introduced to the large alumina synthesized 500 and 600°C and close synthesized when 700 and 800°C. The phase of the alumina was identified only after the synthesized sample at 800°C with crystallite size of 22.16 and 6.75 μm synthesized samples 800 and 900°C, respectively. With respect to morphology, increased synthesis temperature was not enough to significantly change.
The er located master regulation of endosomal positioning and further movements

The endo-lysosomal system is critical to diverse processes, including protein homeostasis, signaling and antigen presentation. The vesicular compartment is organized as a collective unit wherein the bulk of endosomes derived from disparate origins resides in a cloud in the perinuclear region and extends outwards to include quickly moving vesicles in the periphery. At this busy intersection between the endocytic and biosynthetic pathways, lies the late endosomal compartment, responsible for protein degradation and antigen processing. In dendritic and other immune cells, this major constituent of the perinuclear cloud serves as a hub for MHC class II antigen loading. Previous work by us and others has elucidated key elements of MHC class II biology through the study of late endosomal transport to and from the cell periphery. It is clear that cell biology of endosomes is modulated by their proximity to other membrane compartments during transport, maturation, cargo selection and delivery and even during cytokinesis in cell division. However, how endosomal positioning in the perinuclear cloud and how their release for further transport is controlled remains largely unknown. The aim of this proposal is to define the molecular basis for endosomal positioning and then to interrogate the relationship between spatial regulation of the endocytic compartment and its functions with respect to i) MHC class II antigen presentation, ii) bacterial infection and iii) mitotic resolution. From a genome-wide siRNA screen for factors influencing MHC class II biology, we have identified a unique and previously uncharacterized ubiquitin ligase that resides in the ER membrane, from where it controls endosomal positioning and times their arrivals and departures as a function of its catalytic activity. On this basis, the work proposed herein is poised to resolve an entirely new molecular network in control of endosomal biology with implications for diverse biological processes.
Distinct Sources of Hematopoietic Progenitors Emerge before HSCs and Provide Functional Blood Cells in the Mammalian Embryo

Hematopoietic potential arises in mammalian embryos before adult-repopulating hematopoietic stem cells (HSCs). At embryonic day 9.5 (E9.5), we show the first murine definitive erythro-myeloid progenitors (EMPs) have an immunophenotype distinct from primitive hematopoietic progenitors, maturing megakaryocytes and macrophages, and rare B cell potential. EMPs emerge in the yolk sac with erythroid and broad myeloid, but not lymphoid, potential. EMPs migrate to the fetal liver and rapidly differentiate, including production of circulating neutrophils by E11.5. Although the surface markers, transcription factors, and lineage potential associated with EMPs overlap with those found in adult definitive hematopoiesis, they are present in unique combinations or proportions that result in a specialized definitive embryonic progenitor. Furthermore, we find that embryonic stem cell (ESC)-derived hematopoiesis recapitulates early yolk sac hematopoiesis, including primitive, EMP, and rare B cell potential. EMPs do not have long-term potential when transplanted in immunocompromised adults, but they can provide transient adult-like RBC reconstitution.
Effects of doxapram, prethcamide and lobeline on spirometric, blood gas and acid–base variables in healthy new-born calves

A number of drugs have been used to treat asphyxia in new-born calves and the aim of the current study was to investigate the effect of commonly-used stimulant drugs on ventilation, arterial blood gas and acid base variables. A group (n=18) of new-born (3-15 h old) calves were treated in a randomised sequence with doxapram (40 mg, IV), lobeline (5mg, IV) or prethcamide (5 mL, consisting of 375 mg crotethamide and 375 mg cropropamide, buccally). Blood and spirometric measurements, using an ultrasonic spirometer, were collected prior to and 1, 5, 15, 30, 60, 90 min after administration of each drug. Doxapram caused a significant increase in the respiratory rate, peak inspiratory and expiratory flow and minute volume (V(min)) during the 90-min post-treatment study period, although maximum values occurred 1 min after treatment. The V(min) increased from 13.8 ± 5.0 L to 28.5 ± 12.3 L. Prethcamide, but not lobeline, also caused significant increases in inspiratory and expiratory volumes. The effects of doxapram on ventilation were accompanied by an increase in arterial partial pressure of oxygen (P(a)O(2)) (77.7 ± 18.8 mm Hg to 93.2 ± 23.7 mm Hg), a decrease in arterial partial pressure of carbon dioxide (P(a)CO(2)) (42.6 ± 4.9 mm Hg to 33.1 ± 6.6mm Hg), a significant increase in pH and a decrease in bicarbonate concentration and base excess 1 min after treatment. Prethcamide caused a gradual increase in P(a)O(2) and decrease in P(a)CO(2) over 90 min, whereas lobeline had no measurable effect on the investigated variables. Of the three treatments, only doxapram had a distinct stimulatory effect on respiration in healthy neonatal calves and may therefore be useful in the treatment of calf asphyxia.
Advanced mixed realities

The main goal of AdMiRe is to develop, validate and demonstrate innovation solutions, based on Mixed Reality (MR) technology, which will allow for TV audiences a step change in interactivity, and bring for content creators a radical improvement in talent immersion and interaction with computer generated elements. AdMiRe is focused on sectors where the lead industry partners in the consortium are key players, thus guaranteeing the impact of the innovation and the take up of the technology. 
At present, TV audiences can interact with the shows they are watching only through social media or HBBTV. Comments, video and audio from the audience may be incorporated into TV program formats, but this is done in such a way that viewer engagement is quite limited and there is not much potential for innovation. AdMiRe will radically change this by producing solutions that will allow viewers at home to be incorporated into the live TV program they are watching and to interact with people in the TV studio. The key innovation here is to use a regular mobile phone to capture the viewer, extract him/her from the background and finally composite the viewer into the studio footage as an MR object. 
As for content creators, be it in film, TV or live productions, there is an ever growing trend to combine actors and performers with computer generated objects and have them interact. But the number and difficulty of the technical challenges involved have resulted in methods and technologies of reduced scope, resulting in less engaging content. AdMiRe takes the exact opposite approach, producing authoring tools that remove the main technological obstacles and that will allow actors to be immersed in virtual environments, performers to feel at home within the space, and directors to have the opportunity to better capture emotion, all in all resulting in the possibility to create more compelling visuals and more engaging programming.