SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Urban heat island mitigation by green infrastructure in European Functional Urban Areas

The Urban Heat Island (UHI) effect is one of the most harmful environmental hazards for urban dwellers. Climate change is expected to increase the intensity of the UHI effect. In this context, the implementation of Urban Green Infrastructure (UGI) can partially reduce UHI intensity, promoting a resilient urban environment and contributing to climate change adaptation and mitigation. In order to achieve this result, there is a need to systematically integrate UGI into urban planning and legislation, but this process is subject to the availability of widely applicable, easily accessible and quantitative evidence. To offer a big picture of urban heat intensity and opportunities to mitigate high temperatures, we developed a model that reports the Ecosystem Service (ES) of microclimate regulation of UGI in 601 European cities. The model simulates the temperature difference between a baseline and a no-vegetation scenario, extrapolating the role of UGI in mitigating UHI in different urban contexts. Finally, a practical, quantitative indicator that can be applied by policymakers and city administrations has been elaborated, allowing to estimate the amount of urban vegetation that is needed to cool summer temperatures by a certain degree. UGI is found to cool European cities by 1.07 °C on average, and up to 2.9 °C, but in order to achieve a 1 °C drop in urban temperatures, a tree cover of at least 16% is required. The microclimate regulation ES is mostly dependent on the amount of vegetation inside a city and by transpiration and canopy evaporation. Furthermore, in almost 40% of the countries, more than half of the residing population does not benefit from the microclimate regulation service provided by urban vegetation. Widespread implementation of UGI, in particular in arid regions and cities with insufficient tree cover, is key to ensure healthy urban living conditions for citizens.
Climate positive drying system for coffee industries using a highly disruptive pyrolysis technology

PYROTECH is based on a highly disruptive pyrolysis technology as a heating source for drying coffee cherries and makes it possible to produce biochar (a fertilizer used in coffee agriculture). It will displace the market’s “dry methods” for processing coffee, which involves sun drying or the use of heat coming from a conventional burner, which produces heavy smoke, environmental pollution, and lung diseases as well as negatively affecting the quality of coffee cherries quality and resulting in black colouring. PYROTECH is four to ten times cheaper than other pyrolysis systems. It will generate more than 6,5 million euros of additional income for European coffee companies and will eliminate more than 18.000 tonnes of C02 emissions in the first three years due to the carbon sequestration potential of coffee husk used and biochar produced. Currently, more than 9,5 million tonnes of green coffee beans are processed annually, from which 4,8 million tonnes are produced using the dry method. Taking into account the market size, market distribution and current interest of our potential clients, PYROTECH will cover after five years of commercialization, 18% of the total amount of pyrolysis machines needed to dry the coffee cherries. 
Coffee buyers will require farmers to use PYROTECH as a result of the increased quality of the product, the decrease in the selling price and the improved health and safety conditions.
Bayesian nonparametric model with clustering individual co-exposure to pesticides found in the French diet

This work introduces a specific application of Bayesian nonparametric statistics to the food risk analysis framework. The goal was to determine the cocktails of pesticide residues to which the French population is simultaneously exposed through its current diet in order to study their possible combined effects on health through toxicological experiments. To do this, the joint distribution of exposures to a large number of pesticides, which we called the co-exposure distribution, was assessed from the available consumption data and food contamination analyses. We proposed modelling the co-exposure using a Dirichlet process mixture based on a multivariate Gaussian kernel so as to determine groups of individuals with similar co-exposure patterns. Posterior distributions and the optimal partition were computed through a Gibbs sampler based on stick-breaking priors. The study of the correlation matrix of the sub-population co-exposures will be used to define the cocktails of pesticides to which they are jointly exposed at high doses. To reduce the computational burden due to the high data dimensionality, a random-block sampling approach was used. In addition, we propose to account for the uncertainty of food contamination through the introduction of an additional level of hierarchy in the model. The results of both specifications are described and compared.
Seals and sealing practices in sasanian iran: new evidence from taxt-e solaymān

The subject of this application is the publication of an extraordinary collection of 824 Sasanian clay bullae bearing almost 2,000 seal impressions and inscriptions. The collection was recovered by Dr Yousef Moradi, the Experienced Researcher of this application, at the World Heritage site of Taxt-e Solaymān (Western Azerbaijan Province of Iran), the religious complex of Ādur Gušnasp, or ‘Fire of the Warriors’, in 2002–2008 during seven seasons of excavations conducted under the auspices of the Iranian Cultural Heritage Organization (ICHO). While most other Sasanian seals and sealings currently known are unprovenanced, the significance of this collection lies in the fact that it was recovered in a controlled archaeological excavation, with a specific provenance of the bullae. TAXT will produce the publication, both online and in print, of these bullae, and detailed studies of the seal impressions, including images and inscriptions, on the obverse. It will also provide a study of the impressions on the back-sides, or reverses, of the bullae. The reverses have small holes for the cord, and display cord marks and accidental traces of thumb and fingerprints of the persons handling the bullae when impressing the seals into the soft clay and when attaching the bullae to the objects which they were sealing. Moreover, there are imprints of the objects to which the bullae were attached, indicating that the objects were made of leather, grained parchment, and other materials. Coming from one of the three most sacred Zoroastrian fire temples of the Sasanian Empire (224–651 CE), TAXT will reveal unprecedented insights into the economic role of this Zoroastrian fire temple and its priesthood, generating findings that will be of interest to scholars from a variety of disciplines, including linguistics, history, religious studies, art history, and archaeology.
Enabling flexible material flow for smart warehouses and smart factories

The strong growth in e-commerce and consumer expectations for ever-increasing product variety and fast delivery present logistics companies and manufacturers with unprecedented challenges. The digitisation of industry will enable faster, more flexible and more efficient manufacturing, including mass customisation, to meet these challenges but material flow systems have not kept up with the huge strides made in manufacturing. Even current state-of-the-art systems are mechanical constructions that take up a lot of space, whose layout cannot be changed once built and which can carry out only a single pre-defined function. Cellumation's innovation is the celluveyor, a multi-functional software-driven conveying and positioning system designed to make material flow systems faster, completely flexible and more efficient. The system's core consists of hexagonal cells with several individually driven omnidirectional wheels. These cells form a flat surface, in a ""Lego""-like structure, with the moving wheels uppermost. Objects sit on this surface and are moved by the action of the turning wheels. Each system takes up to 95% less space than competing systems, can handle all functions required and the function can be changed by customers' staff with a few clicks on a laptop. Cellumation has sold nine TRL6 prototype systems in Germany, Spain and the UK. The market is huge at €26bn+: every factory and every logistics centre has conveyor belts. Cellumation has keen buying interest from several well-known manufacturing companies in the EU and the US. The objectives of this project are to reduce cell costs by 50%, to expand functionality to include limp plastics as well as smaller objects and to ensure that our software and the entire system are easy to use. Cellumation's goal is for celluveyor to become the state-of-the-art conveyor technology and a key part of the distribution centres and manufacturing plants of the future.
Successful Treatment of Recalcitrant Prurigo with Alitretinoin

Chronic itch with secondary scratch lesions such as prurigo has a major impact on quality of life. Due to its relapsing nature and often unknown origin, its treatment is challenging.We sought to demonstrate that alitretinoin can be an efficacious and well-tolerated treatment in a patient suffering from chronic itch with concomitant prurigo and psoriatic lesions.Case report.After 1 month of alitretinoin treatment (30 mg daily), itch as well as prurigo and psoriasis lesions decreased markedly. Three cycles of alitretinoin were administered, as each cessation of treatment led to relapse of the symptoms after 6-8 weeks. Tapering of the alitretinoin dose (30 mg every second day) after the third cycle allowed to maintain the effects for over 18 months.Treatment of refractory prurigo with alitretinoin might be an efficacious alternative to standard therapies. In case of relapse, retreatment with alitretinoin reinduces a further long-lasting response.
A rotary transmission coupling

A rotary transmission coupling (1) is disclosed for selectively providing drive to an output such as a driven wheel (115, 116) of a motor vehicle (100). The rotary transmission coupling (1) includes a friction clutch (2) and a hydraulic actuator assembly (20) that receives fluid at pressure from a remote pump (206, 216) controlled by an electronic control unit (202). The actuator assembly (20) includes a hydraulic actuator formed by a body (21) that slidingly supports a piston (25) used to operate the friction clutch (2). The body (21) is restrained from rotation by a number of spigots (24, 35, 36) that allow limited translation of the body (21) to accommodate tolerance build-up within a transmission assembly (123) of which the rotary coupling (1) forms a part. The hydraulic actuator is attached to a clutch cover (4) of the friction clutch (2) such that the reaction force from the hydraulic actuator is resisted solely by the clutch cover (4) and is not transferred to any other components of the rotary transmission coupling (1).
SMALL ORGANIC MOLECULE REGULATORS OF CELL PROLIFERATION

The present invention makes available methods and reagents for modulating proliferation or differentiation in a cell or tissue comprising contacting the cell with a compound. In certain embodiments, the methods and reagents may be employed to correct or inhibit an aberrant or unwanted growth state, e.g., by antagonizing a normal patched pathway or agonizing smoothened orhedgehog activity.
The curiosity carnival: oxford european researchers’ night 2017

By capitalising on the University of Oxford’s world-class European-funded research base, together with our outstanding  museums, libraries, gardens and woods, education programmes and public engagement expertise, we will create a truly inspirational multi-venue multi-disciplinary European Research night in 2017 on the theme of  ‘People and Planet'.

The event itself will be a city-wide programme of high quality and innovative activities utilising both University of Oxford venues in addition to busking-type activities taking place in shopping centre locations. Each venue will have its own ‘flavour’ – focusing on specific research topics and encompassing different activities - so that there will be ‘something for everyone’.

By focusing on quantity and quality, we will create a much bigger impact on the audiences and participating researchers and create a long lasting legacy. 

Objectives: 

a) Organise an inspirational large-scale public engagement with research event at 8 different venues and locations that engages 10,000+ people via the live activities and 250,000+ via digital and media activities.

b) Increase awareness of research and its impact on society to an audience of young people and their influencers.

c) Enable at least 200 researchers, including a significant proportion of female researchers, to take part.

d) Inspire young people to consider a career in research

e) Share our challenges, successes and lessons learnt.

Activities will include interactive stalls; games; mass experiments; science ‘demos’; a ‘living library’ for the public to take out a researcher 'on loan' and two grand finales with musical performances.

The awareness campaign will facilitate even greater public-researcher engagement across digital and media platforms. This will include a fun and educational online activity for school pupils to interact with researchers.
 
The in-depth impact assessment will utilise baseline data and both quantitative and qualitative methods.
Disrupting aberrant protein–protein interactions with conformationally constrained hydrocarbon α-helical mimetics

Many critical processes within cells, including those that control whether a cell lives and divides or dies, are mediated by protein–protein interactions (PPIs). In certain disease states, such as cancer, these interactions can become defective in a way where disruption of the interaction has therapeutic benefit. Replacement of one of the protein partners, which often have α-helical secondary structure, with a small molecule is one method of disruption; however, the interface can often be large and shallow, making the design of competitive small molecules challenging. The saving grace is that the interaction energy is usually dominated by the interactions of a few amino acid residues, which protrude from one or more faces of the α-helical peptide. The design of α-helical mimetics that are non-peptidic in nature and that can replicate the positioning of these hotspot residues has been an active area of research. The host laboratory has recently developed a method to prepare chains of substituted carbon atoms with complete control of absolute and relative configuration. Owing to the avoidance of syn-pentane interactions, the all-syn and alternating syn–anti contiguously substituted chains fold into well-defined helical and linear conformations. The positioning of the substituents could uniquely replicate a pattern of hotspot residues that cover two or more faces of an α-helical peptide. This project will explore this possibility through the design, preparation and testing of mimetics that target the Mcl-1/Noxa-B PPI, which controls apoptosis and has leucine, arginine, isoleucine, aspartic acid, and valine at positions 11, 12, 14, 16 and 18 as hotspot residues. The project merges cutting-edge synthetic organic chemistry, multiple forms of computation, including molecular mechanics, density functional theory, and molecular dynamics, NMR spectroscopy, and medicinal chemistry.
Does temperature contain a stochastic trend? Evaluating conflicting statistical results

We evaluate the claim by Gay et al. (Clim Change 94:333-349, 2009) that temperature can be better described as a trend stationary process with a one-time permanent than efforts by Kaufmann et al. (Clim Change 77:249-278, 2006) to model surface temperature as a time series that contains a stochastic trend that is imparted by the time series for radiative forcing. We test this claim by comparing the in-sample forecast generated by the trend stationary model with a one-time permanent shock to the in-sample forecast generated by a cointegration/error correction model that is assumed to be stable over the 1870- 2000 sample period. Results indicate that the in-sample forecast generated by the cointegration/error correction model is more accurate than the in-sample forecast generated by the trend stationary model with a one-time permanent shock. Further- more, Monte Carlo simulations of the cointegration/error correction model generate time series for temperature that are consistent with the trend-stationary-with-a-break result generated by Gay et al. (Clim Change 94:333-349, 2009), while the time series for radiative forcing cannot be modeled as trend stationary with a one-time shock. Based on these results, we argue that modeling surface temperature as a time series that shares a stochastic trend with radiative forcing offers the possibility of greater insights regarding the potential causes of climate change and efforts to slow its progression.
African governance and space: transport corridors, border towns and port cities in transition

AFRIGOS investigates the process of 'respacing' Africa, a political drive towards regional and continental integration, on the one hand, and the re-casting of Africa's engagement with the global economy, on the other. This is reflected in unprecedented levels of investment in physical and communications infrastructure, and the outsourcing of key functions of Customs, Immigration and security agencies. AFRIGOS poses the question of how far respacing is genuinely forging institutions that are facilitating or obstructing the movement of people and goods; that are enabling or preventing urban and border spaces from being more effectively and responsively governed; and that take into account the needs of African populations whose livelihoods are rooted in mobility and informality. The principal research questions are approached through a comparative study of port cities, border towns and other strategic nodes situated along the busiest transport corridors in East, Central, West and Southern Africa. These represent sites of remarkable dynamism and cosmopolitanism, which reflects their role in connecting African urban centres to each other and to other global cities.

AFRIGOS considers how governance 'assemblages' are forged at different scales and is explicitly comparative. It works through 5 connected Streams that address specific questions: 1. AGENDA-SETTING is concerned with policy (re-)formulation. 2. PERIPHERAL URBANISM examines governance in border towns and port cities. 3. BORDER WORKERS addresses everyday governance emerging through the interaction of officials and others who make their livelihoods from the border. 4. CONNECTIVE INFRASTRUCTURE looks as the transformative effects of new technologies. 5. PEOPLE & GOODS IN MOTION traces the passage of people and goods and the regimes of regulation to which they are subjected. AFRIGOS contributes to interdisciplinary research on borderland studies, multi-level governance and the everyday state.
Modified gravity away from a ΛCDM background

Within the effective field theory approach to cosmic acceleration, the background expansion can be specified separately from the gravitational modifications. We explore the impact of modified gravity in a background different from a cosmological constant plus cold dark matter ($\Lambda$CDM) on the stability and cosmological observables, including covariance between gravity and expansion parameters. In No Slip Gravity the more general background allows more gravitational freedom, including both positive and negative Planck mass running. We examine the effects on cosmic structure growth, as well as showing that a viable positive integrated Sachs-Wolfe effect crosscorrelation easily arises from this modified gravity theory. Using current data we constrain parameters with a Monte Carlo analysis, finding a maximum running $|\alpha_M|\lesssim 0.03$. We provide the modified {\tt hi\_class} code publicly on GitHub, now enabling computation and inclusion of the redshift space distortion observable $f\sigma_8$ as well as the No Slip Gravity modifications.
Unterstützung von Unternehmen, die gemäß dem Tourismusgesetz als Reiseveranstalter oder Reisebüro registriert sind, um die wirtschaftlichen Folgen der COVID-19-Pandemie zu überwinden

Unterstützung von Unternehmen, die gemäß dem Tourismusgesetz als Reiseveranstalter oder Reisebüro registriert sind, um die wirtschaftlichen Folgen der COVID-19-Pandemie zu überwinden
Neoadjuvant Therapy for Potentially Resectable Pancreatic Cancer: An Emerging Paradigm?

Although neoadjuvant chemoradiotherapy has been tested for more than two decades and can be safely delivered to patients with non-metastatic pancreatic cancer, no randomised trials have been reported until now. Here we provide an overview of the first randomised trial in patients with potentially resectable cancer and of the latest developments in neoadjuvant therapy for this group of patients. It is necessary to continue to perform clinical trials in this field to accurately identify the effect on survival and quality of life in patients with potentially resectable, borderline resectable and unresectable pancreatic cancer. Aspects of imaging for restaging and clinical prognostic factors are also discussed given they will be useful instruments for future trials.
”TÄMÄ PUHELIN ON TAIVAAN LAHJA” : Vertaislinja muistisairauden kanssa elävän tukena

Puhakka Karoliina Peer-listening phone service supporting people with dementia and their family 43 p., 1 appendix. Language: Finnish. Helsinki, Spring 2011. Diaconia University of Applied Sciences. Degree Programme in Nursing, Option in Nursing. Degree: Nurse. Peer-support is one of the relative s or dementia suffering person s form of support. It helps coping with dementia. Health care professionals should guide relatives and dementia patients to this significant support. The aim of this study was to establish what the needs of information and support were for those people who call to Vertaislinja of Muistiliitto (Alzheimer Society of Finland). Vertaislinja is a peer-listening phone service. Volunteers work at this phone service and they fill in a form based on every call. Muistiliitto society has stored every form since the phone service was established in 2004. From this material I chose all the forms from year 2008. The final number of research material consisted of 266 forms. I analyzed the callers and the call topics from the forms as well as where the volunteers referred the callers to during the call. The typical caller of Vertaislinja was a wife of a person with Alzheimer s disease (n=80) or their daughter (n=79). The most common topic of the call was telling about concerns (n=89). Usually the caller wanted to tell their concerns about daily matters. The second most common topic was talking about the symptoms and the research of the disease (n=74). In all 53 calls, callers wanted to ask advice or receive information on something. Based on the results of this thesis, relatives and people close to the person suffering from dementia as well as the person themselves need some information of the disease, its symptoms and advice on daily situations as well as information on peer group activity. Sometimes volunteers also refer callers to peer groups and other recreational activities. According to the results, family members and people with dementia need also information that only health care professionals can provide.