SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
MYMEMO Â INNOVATIVE MEDICAL DISPENSER

RGF DIAGNOSTICS IS AN INNOVATIVE START-UP FOUNDED BY ROEE DVIR AND GIORGIO PIZZAGALLI, TWO PHYSICIANS SPECIALISED IN MICROBIOLOGY AND CLINICAL VIROLOGY AND CLINICAL BIOCHEMISTRY WHO HAVE BEEN ACTIVE IN THE FIELD OF LABORATORY DIAGNOSTICS FOR 9 YEARS. THE MYMEMO PROJECT IS BORN FROM DOCTORS WITH INCREASING EXPERIENCE IN MANAGING PATIENTS WITH CHRONIC-DEGENERATIVE DISEASES. GLOBALLY, CHRONIC DISEASES ARE RESPONSIBLE FOR 86 % OF ALL DEATHS AND IT IS EXPECTED THAT BY 2020 THEY WILL ACCOUNT FOR 80 % OF ALL DISEASES IN THE WORLD.FROM THESE ASSESSMENTS, MYMEMO IS BORN, AN EASY-TO-USE CUSTOM PILLS DISTRIBUTOR. USERS PROGRAM THE DEVICE VIA UNÂAPP MOBILE AND THE DRUGS ARE PROGRAMMED AND DISTRIBUTED AS NEEDED. THE OPERATION IS SIMPLE: JUST ENTER THE NAME OF THE DRUG, THE DOSE AND THE TIME, THEN PRESS THE LOADING BUTTON. MYMEMO WILL AUTOMATICALLY PLACE THE CORRECT PILL CONTAINER UNDER THE DOOR OF THE TOP SAFE BLO
A coherent view of glasses: how coherent x-rays can elucidate the complex dynamics of glasses

Glasses are mysterious materials. Fundamental blocks in many natural and technological processes, still, their properties keep puzzling a large community of scientists nowadays. Following different experimental routes, materials as diverse as colloidal suspensions, emulsions and viscous liquids can be driven in an out-of-equilibrium state, where they solidify under conditions that still remain unknown. This process, traditionally called glass transition, leads to many intriguing phenomena as the emergence of multiple relaxations processes, dynamical heterogeneities, crossovers between distinct amorphous states, and uncommon mechanisms of particle motions.  
Within the large family of disordered systems, structural glasses play a key role being often considered as archetypes of out-of-equilibrium materials. Despite decades of studies, a microscopic theory of glasses is still missing due to the difficulty to probe their atomic motion with experiments and simulations. 
Few years ago, I used coherent x-rays to perform the first worldwide experiments probing the atomic motion of glasses. My works reported on a surprising glassy dynamic reminiscent of an anomalous stress-driven particle motion observed in some soft systems. Due to severe technical constraints, the studies performed so far were limited to the external, tiny portion of the huge ""iceberg” of dynamical features occurring at the atomic level, whose comprehension would enable substantial advances in the frontiers of knowledge.
Thanks to the new possibilities offered by coherent x-rays, now is the right time to unveil the atomic dance of glasses in all its complexity with the CoherentGlasses project. Following four challenging experimental Research Objectives, we will provide a coherent picture of the microscopic dynamic and structural features accounting for the above discussed fascinating phenomena in glass-formers. 
A successful project keeps the promise to boost our knowledge on out-of-equilibrium material.
MicroRNA-212 suppresses tumor growth of human hepatocellular carcinoma by targeting FOXA1

MicroRNA-212 (miR-212) has been reported to play oncogenic or tumor suppressive role in different human malignancies. Here, we demonstrated that the mean level of miR-212 in hepatocellular carcinoma (HCC) tissues was significantly lower than that in matched tumor-adjacent tissues. Similarly, the expression of miR-212 was obviously reduced in HCC cell lines as compared with a nontransformed hepatic cell line. Ectopic expression of miR-212 inhibited cell viability and proliferation, and induced apoptosis in HepG2 cells. In contrast, down-regulation of miR-212 increased cell viability and proliferation, and suppressed apoptosis in Bel-7402 cells. In vivo studies showed that miR-212 inhibited tumor growth of HCC via suppressing proliferation and inducing apoptosis. Furthermore, we confirmed that Forkhead box protein A1 (FOXA1) was a direct target of miR-212, and it abrogated the function of miR-212 in HCC. Finally, we disclosed that the aberrant expression of miR-212 and FOXA1 was evidently correlated with poor prognostic features of HCC. MiR-212, FOXA1 and their combination were valuable prognostic markers for predicting survival of HCC patients. In conclusion, miR-212 may serve as a prognostic indicator for HCC patients and exerts tumor suppressive role, at least in part, by inhibiting FOXA1.
Rapid access to functionalized cyclobutanes via ring expansion strategies

Cyclobutanes are common motifs in natural products and are increasingly important in medicinal chemistry since they can orient substituents along precise vectors. However, methods to construct cyclobutanes are less developed in comparison to their smaller and larger rings. Consequently, novel methods to access functionalized cyclobutanes are highly desirable and would be of considerable value for the discovery of new bioactive compounds. In the last decade, the host group and others have contributed significantly to the development of boron 1,2-migration chemistry which has found numerous applications in organic synthesis. Normally, 1,2-metallate shifts in boronate complexes are induced by α-leaving groups or by reactions of alkenyl boronates with halogens, π-acidic metals, or radicals. Herein, we are proposing a fundamentally new strategy to induce 1,2-metallate rearrangement, via a ring expansion of vinyl cyclopropyl boronate complex activated by an electrophile or by photoredox or transition metal catalysis. This novel process would lead to highly versatile boronic ester containing cyclobutanes, which can be transformed into other valuable functional groups. Furthermore, we plan to use chiral ligands in combination with palladium catalysis in this novel process, leading to enantioenriched chiral cyclobutyl boronic esters. These novel methodologies not only benefit from the formation of highly functionalized cyclobutanes, but also lay solid foundations for the development of other ring-expansion induced 1,2-metallate rearrangements. The scope of these processes will be carefully investigated, and mechanistic studies of the photoreaction will be carried out using advanced physical/chemical methods. Finally, this project will enable significant knowledge transfer between the host and researcher, while forging new academic networks within the scientific community.
Alicyclic Compounds

1,168,783. Adamantylethanol. LILLY INDUSTRIES Ltd. 26 Oct., 1966 [3 Aug., 1965], No. 29747/66. Divided out of 1,168,781. Heading C2C. The invention comprises 2-(1-adamantyl)- ethanol, and a method of making it by reducing (e.g. with LIAlH 4 ) (1-adamantyl) acetic acid, or an alkyl ester or acid halide thereof. (1-Adomantyl) acetic acid is prepared by thermally decomposing (1-adamantyl) malonic acid.
Patients With Locally Advanced and Metastatic Colorectal Cancer Treated With Capecitabine Versus 5-Fluorouracil as Monotherapy or Combination Therapy With Oxaliplatin: A Cost Comparison

This study quantified the costs associated with the acquisition of chemotherapy, its administration, and the management of chemotherapy-related complications, and their effect on total patient expenditures.Patients with locally advanced and metastatic colorectal cancer treated with capecitabine or 5-fluorouracil/leucovorin (5-FU/LV) as monotherapy or combination therapy with oxaliplatin from 2003-2006 were identified in the Thomson Reuters MarketScan® databases. Selection bias between treatment groups was addressed by propensity score matching, assessment of the risk of complications using Cox models, and an estimate of expenditures using general linear models.In respect to monotherapy, capecitabine users (n = 1272) were propensity score matched to 5-FU/LV users on a 1:1 ratio. The adjusted mean monthly cost was significantly lower for patients treated with capecitabine versus 5-FU/LV ($6683 vs. $9304, respectively; P < .0001). Although the cost of drug acquisition was significantly higher for capecitabine than for 5-FU/LV (unadjusted P < .0001), significantly lower costs of capecitabine administration (unadjusted P < .0001) and management of complications (adjusted costs, P < .0001) offset the difference, and drove a lower overall cost. In regard to combination therapy, capecitabine/oxaliplatin users (n = 263) were propensity score matched to 5-FU/LV/oxaliplatin users (n = 526) on a 1:2 ratio. The adjusted mean monthly cost was significantly lower for capecitabine/oxaliplatin than for 5-FU/LV/oxaliplatin ($11,436 vs. $14,320, respectively; P < .0001). The cost difference was driven by the significantly lower administration costs of capecitabine-based chemotherapy (unadjusted P < .0001) and management of complications (adjusted P < .0001).The monthly cost per patient during capecitabine or capecitabine/oxaliplatin treatment is significantly lower than during 5-FU/LV or 5-FU/LV/oxaliplatin treatment because of lower costs for the administration of chemotherapy and for the management of complications.
Advanced laser ablation barrier films for organic and large area electronic devices

The overall objective of this project is developing organic electronic building elements on flexible substrates with monolithically integrated barrier foils as substrate. The barrier acts as the inevitable protection against atmospheric gases as water vapor and oxygen, as the most crucial agents for unwanted material degradation processes. This topic is one of the keys for enhancing both the performance of TOLAE components and addresses some of the main technology barriers of TOLAE: lifetime and cost-performance-ratio.
Organic photovoltaic (OPV) modules have been chosen as test objects for a scalable and general approach suitable also for other TOLAE devices. Monolithical integration of barrier foils means in this case that the full device is made immediately on top of ultra-barrier coated plastic foil, which further is coated with a transparent electrode. This leads to significant cost reduction, which is one of the key needs for wider use of TOLAE devices.
The project ALABO develops direct laser scribing processes on flexible substrates, coated with ultra-barrier systems. The project results will be applicable to a number of TOLAE technologies, such as OPV, OLED, OTFT and thin-film inorganic PV on polymer foil substrates. The consortium will investigate and develop new manufacturing processes, which will increase the performance and functionality of TOLAE devices suitable for smart systems. OPV can be part of such smart TOLAE systems. By developing direct laser structuring on top of such ultra-barrier foil, the consortium develops advanced materials, as well as new production technologies supported by dedicated monitoring and material testing technologies for well-scalable manufacturing processes. As an outcome, more functionality will be integrated into less material, since in - contrast to state-of-the-art encapsulation processes - the devices will need only one foil per side, instead of at least two today.
The origin of heavy elements: a nuclear physics and astrophysics challenge

Where in the universe are heavy elements synthesized? How are these elements produced? These are two exciting and interdisciplinary questions in nuclear astrophysics today and will be investigated in my ERC project EUROPIUM. The favored astrophysical sites are neutrino-driven winds following core-collapse supernovae and neutron star mergers, where extreme conditions enable the rapid neutron capture process (r-process). We will perform long-time multidimensional simulations of these two scenarios and combine them with nucleosynthesis calculations. In neutron star mergers, the radioactive decay of neutron-rich nuclei triggers an electromagnetic signal known as kilonova. This was potentially observed in 2013 after a short gamma ray burst, associated with a neutron star merger. We will simulate the neutrino- and viscous-driven ejecta from the disk that forms after the merger around the central compact object. In addition, we will investigate supernova neutrino-driven winds that produce lighter heavy elements from strontium to silver. We will explore the impact of rotation, improved microphysics, and magnetic fields on the wind evolution and nucleosynthesis. Because the synthesis of lighter heavy elements elements occurs closer to stability, the nuclear physics uncertainties will be reduced by experiments in the near future. This will uniquely allow us to combine observations and nucleosynthesis calculations to constrain the astrophysical conditions and gain new insights into core-collapse supernovae. In nuclear physics, a new era for extreme neutron-rich isotopes is starting with new experimental facilities. Based on our simulations, we will study the impact of the nuclear physics input (nuclear masses, beta decays, neutron captures, and fission) going beyond the state-of-the-art by providing r-process abundances with uncertainties. Comparing our results with forefront observations of the oldest stars will in turn provide new insights about the origin of heavy elements.
A study of spatial and temporal distribution of land utilization pattern in Mopka village using RS & GIS

Remote Sensing and GIS is a very good modality for retrospection and the strategy for better exploitation of sustainable land use system. The present study was conducted in the Bilaspur district for analyzing the spatial distribution of Land Use Change. During last decades the increasing population of Bilaspur city, affect the land use pattern of Mopka Village. The anthropogenic activities were affecting the agricultural land along with barren land. For the development of civic amenities the land of the above village was used. The main objective of the present study is to analyses the land use/land cover distribution in Mopka village, Bilaspur district in between last 12 years and to identify the main forces behind the changes. The objectives of present studies are, to create a land use land cover maps of Mopka village using satellite imagery. To analysis the temporal changes of village area in between the year 2000 and 2012, the primary, secondary and satellite data were used. The results of the present study show that the decadeial changes due to population growth and increasing demand of infrastructure were destroying the natural resources, natural habitat and soil structure of area.Int. J. Agril. Res. Innov. &amp; Tech. 5 (1): 1-9, June, 2015
Développement de nouveaux roulements industriels à haute stabilité de fonctionnement à l’état déchargé? roulements à digue hydrodynamique

Le projet porte sur la recherche et le développement d’une nouvelle gamme de roulements de profilés à haute stabilité de fonctionnement à l’état déchargé pour la stabilisation des arbres, en particulier dans les machines à grande vitesse, qui transmettent des sorties élevées avec des vitesses et des vitesses élevées à couple relativement faible. Les travaux de recherche dans le cadre du projet sont axés sur la formation et l’impact ultérieur de barrages hydrodynamiques qui amplifient le débit d’huile dans l’incidence sur l’amortissement, les vibrations et le comportement à différents états et vitesses.
Failed fertilization with conventional oocyte insemination can be overcome with the ability of ICSI according to binding or failing to bind to the zona pellucida

To determine the frequency of failed fertilization with conventional oocyte insemination and to determine the ability of intracytoplasmic sperm injection (ICSI) to overcome the failed fertilization according to binding or failing to bind to the zona pellucida. Materials and Methods: Retrospective review of 12,448 in vitro fertilization (IVF) cycle to identify cycles where failed fertilization occurred following conventional oocyte insemination with seemingly normal sperm. A number of three oocytes retrieved was required. Results: There were only 12 cases of failed fertilization (0.1%). Six were related to failure of any or few sperm attaching to the zona pellucida These six had high fertilization rates with ICSI. Six had normal attachment and five attempted another cycle, this time with ICSI. Only 60% had good fertilization. Conclusions: When there is failed fertilization with normal sperm oocyte binding following conventional oocyte insemination, ICSI may still be effective in 60% of the cases, but it would be probably recommended to combine ICSI with artificial oocyte activation by calcium ionophore.
Mappatura e ricerca partner per case di tronchi nel nord della Cina. Localizzazione di un prodotto finlandese della casa di tronchi al mercato cinese. Assumere una persona chiave per aprire nuovi mercati in Oriente.

L'obiettivo del progetto è quello di trovare importatori a Rovaniemi hirsitalot Oy dal nord della Cina, che sono climaticamente adatti per la costruzione di case di tronchi. I modelli di casa più richiesti (Scandinavia, Jazz, Gloria, casa svedese, Laplandia) sono localizzati per il mercato cinese utilizzando un esperto locale. La certificazione antincendio per i tronchi è ottenuta tramite un consulente locale. Per le esportazioni verso l'Est, una "persona chiave" sarà assunta per mappare nuovi mercati e portare i clienti da nuovi mercati.Partecipazione per lo spettacolo 3/2015 a Pechino
Adriatic - Danube - Black Sea multimodal platform

The idea of the project is to develop and promote environmentally friendly, multimodal transport solutions from the ports in the SEE programme area (Black Sea, Aegean, Adriatic) to inland countries and regions along a selected pilot transnational network. This will be done by developing and establishing a "multimodal transport development platform", which integrates different regions and stakeholders from the transport business. ADB Multiplatform aims at: 1) developing a network of multimodal hubs in SEE area, with common quality and performance standards, connected by innovative ICT and transport services; 2) developing accessibility and trade within SEE area and corridors addressed; 3) making multimodal transport a real alternative to road for hinterland traffic catchable by Adriatic/Aegean/Black Sea Ports, through common development actions of multimodal transport; 4) making rail a reliable solution for economic operators of SEE area, through the development of a main integrated rail corridor connecting Black Sea to landlocked countries, with branches to main Adriatic Ports; 5) integration of rail and inland waterway transport through the enhancement of main rail-river hubs and promotion of rail-water intermodality; 6) protecting environment of SEE area, through the shift of road traffic to rail and inland waterway, and the development of international agreements for developing policies for external costs internalisation.
meng gu guo dong nan bu ba yin su he tu wan gu sheng dai zao zhong sheng dai er chang hua gang yan di qiu hua xue te zheng ji qi dui gou zao huan jing de yue shu

Located between the northern margin of Erlian-Hegenshan suture zone and the pericontinental accretion zone of the southeastern margin of the Siberia plate,the Bayinsukhtu granitic body is an intrusive complex composed of monzonitic granites emplaced at Carboniferous and Triassic-Jurassic respectively.Geochemical analyses suggest that both of the two periods of monzonitic granites are characterized by high contents of silica,Al2O3 and alkali,low contents of calcium and magnesium.They are enriched in LILE and depleted in HFSE,with moderately enrichment of LREE,weak fractionation of LREE from HREE and negative Eu anomalies(δEu = 0.35-0.66).Based on the petrologic and geochemical features,the Carboniferous monzonitic granite is classified as mainly high-K,calc-alkaline,metaluminous to weakly peraluminous syn-orogenic I-type granite,while the latter is A-type granite.Isotope geochemistry of the Carboniferous granite shows that values of eNd(t) and(87Sr/86Sr)i range from 0.9 to 1.5,and from 0.700 62 to 0.704 82,respectively,which indicates that the granitic magma was likely derived from a young mantle source or an accretionary island arc with some degree of crustal contamination.However,the Triassic-Jurassic granite has lower eNd(t) but higher(87Sr/86Sr)i values relative to the Carboniferous granite,ranging from-0.3 to 0.3 and from 0.709 96 to 0.710 19,respectively.This indicates the granite derived from the same source with relatively high degree of crustal contamination.The dating of zircons from the monzonitic granites determined by LA-ICP-MS yielded a weighted age of(296±3.5) Ma,indicating that in the late Carboniferous the studied area was a syn-collision pericontinental tectonic environment.According to geochemical analysis of Late Triassic-Early Jurassic granite,it is presumed that the syn-collisional magmatism lasted till Triassic-Jurassic,probably suggestive of a long duration of collision.
NOÉ - NOÉ - Patrimoine et prévention des risques naturels

Heritage is a major factor in relation to cultural identity, the development of regional economies and tourism. In the event of a natural disaster, all elements of heritage are affected as a result of there being insufficient adapted and/or preventive strategies or emergency plans. In order to be effective, emergency measures must be carried out at regional level and in close cooperation with the different concerned parties and decision-makers: local authorities (towns, regions and states), risk prevention experts (hydrogeologists, seismologists), intervention services (fire brigade). It is in this context of prevention that five European regions have decided to collaborate in order to anticipate risks and preserve the richness of their heritage. Overall objective / Objectif général NOÉ aims to raise awareness among all local representatives by means of organised regional actions. It aims to develop an innovative and multidisciplinary approach, in order to establish an interregional operation to protect heritage from damage and aid intervention efforts in the event of a disaster. These strategic instruments, cooperatively developed and inspired by conclusive research from all partners, will be issued and disseminated to be implemented in other regions. Expected results / Résultats attendus The actions and sub-projects carried out in the framework of the NOÉ project will enable: • better transregional cooperation; • the optimisation of professional expertise; • skills transfer between the regions; • the development of assistance tools for professionals carrying out prevention plans in the event of damage; • the dissemination -through the use of NITC- of data that is required to superimpose a risk map on a heritage map in risk areas; • the establishment of adapted communication systems; • the organisation of in-house and distance training networks using NTIC; • the organisation of intervention brigades for mutual assistance between regions.