SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Fibrous nanocrystals of hydroxyapatite loaded with TiO2 nanoparticles for the capture and photocatalytic decomposition of specific proteins

The monomolecular adsorption of lysozyme (LSZ) and bovine serum albumin (BSA) on hydroxyapatite (HAp) was observed by using two types of fibrous crystals elongated in the c-axis. Selective removal of the specific proteins was achieved by the capture and decomposition on the HAp crystals having the particular nanostructures attached with anatase-type TiO(2). Bundled short nanorods of ca. 10nm in diameter were suitable for the capture of a relatively small protein molecule, LSZ, due to their high specific surface area, while the adsorption of a relatively large molecule, BSA, was restricted because of the narrow clearance gap between the nanorods. On the other hand, the large protein preferentially adsorbed to long nanoneedles of 30-60 nm in diameter, which had a wide gap among the loosely aggregated crystals. The captured proteins were smoothly decomposed with anatase nanoparticles loaded on the fibrous HAp crystals under UV irradiation. Thus, the photocatalytic activity for the decomposition of proteins could be controlled with the adsorption on the surface of the nanostructured HAp crystals.
INSULATED CONCRETTE FORM AND METHOD OF USING SAME

The invention comprises connector for a pair of opposed spaced concrete forming panels. The connector comprises an elongate spacer member having flanges formed thereon intermediate a central portion thereof and each opposite end thereof. A portion of at least one end of the spacer member is sized and shaped to selectively engage an elongate panel bracing member. A composite insulated concrete form and a method of using the insulated concrete form are also disclosed.
Affective and Emotional Determinants of Entrepreneurial Orientation Within Family Firms

As a predominant form of business organization, family firms have attracted increasing attention by scholars, and especially by those researching entrepreneurial orientation with the aim of better understanding of entrepreneurial activities pursued by enterprises. However, the literature on the confluence of entrepreneurial orientation and family firms has paid scant attention to the influence of affective and emotional factors. To cover this research gap, the authors analyze the impact of affective commitment and concern for socioemotional wealth preservation on entrepreneurial orientation. To do so, they performed an empirical study using the data collected from 342 small and mid-sized family firms from Portugal, a country where family firms are under-researched even though they make up the backbone of the economy. Results show that both affective commitment and socioemotional wealth positively impact entrepreneurial orientation, pointing to the need to further research the relationships between such factors and strategic behaviors in the family business context.
Knowledge capture in the wild

Semantic wikis augment wikis with semantic properties that can be used to structure content that can therefore be aggregated and queried through reasoning. Semantic wikis have been adopted by many communities for very diverse purposes, such as organizing genomic knowledge, coding software, learn about hobbies, and tracking environmental data. Although wikis have been analyzed extensively, there has been little analysis of the use of semantic wikis. In this paper, we analyze the formalization of knowledge in 230 semantic wiki communities. We report our findings in terms of the edits of semantic concepts and properties, as well as the communities of editors for these semantic features of the wikis.
Industry 4.0 for smes - smart manufacturing and logistics for smes in an x-to-order and mass customization environment

Industry 4.0 refers to the fourth industrial revolution and technological evolution from embedded systems to cyber-physical systems (CPS) in production. The main objectives of Industry 4.0 can be summarized as the introduction of intelligent systems in production and logistics, the development of highly adaptable and modular manufacturing and logistics systems, the integration of sustainable and advanced manufacturing technologies as well as the promotion of automation technology and human-machine interaction. In the context of Industry 4.0 new ICT and web technologies act as booster or enabler of smart, autonomous and self-learning factories facing the challenges of even more individualized and customized product portfolio.
A great challenge for the future lies in the transfer of Industry 4.0 expertise and technologies in small and medium sized enterprises (SME). SMEs represent the backbone of the economy and have an enormous importance in the development programs of the European Union for strengthening the competitiveness of European enterprises. Although the high potential of Industry 4.0 in SMEs, the main limit lies in a lack of concrete models for its implementation and application in small and medium enterprises. Thus, this research project titled “Industry 4.0 for SMEs - Smart Manufacturing and Logistics for SMEs in an X-to-order and Mass Customization Environment” aims to close and overcome this gap through the creation of an international and interdisciplinary research network. Identifying the needs and enablers for a smart and intelligent SME-Factory, creating adapted concepts and design solutions for production and logistics systems in SMEs and developing suitable organisation and business models will be the three main objectives of this research network. The applicability of the results is ensured through a close collaboration with a European small and medium sized enterprise (non-academic partner) from mass customization industry.
Mechanism Design via Correlation Gap

For revenue and welfare maximization in single-dimensional Bayesian settings, Chawla et al. (STOC10) recently showed that sequential posted-price mechanisms (SPMs), though simple in form, can perform surprisingly well compared to the optimal mechanisms. In this paper, we give a theoretical explanation of this fact, based on a connection to the notion of correlation gap. Loosely speaking, for auction environments with matroid constraints, we can relate the performance of a mechanism to the expectation of a monotone submodular function over a random set. This random set corresponds to the winner set for the optimal mechanism, which is highly correlated, and corresponds to certain demand set for SPMs, which is independent. The notion of correlation gap of Agrawal et al.\ (SODA10) quantifies how much we {}"lose" in the expectation of the function by ignoring correlation in the random set, and hence bounds our loss in using certain SPM instead of the optimal mechanism. Furthermore, the correlation gap of a monotone and submodular function is known to be small, and it follows that certain SPM can approximate the optimal mechanism by a good constant factor. Exploiting this connection, we give tight analysis of a greedy-based SPM of Chawla et al.\ for several environments. In particular, we show that it gives an $e/(e-1)$-approximation for matroid environments, gives asymptotically a $1/(1-1/\sqrt{2\pi k})$-approximation for the important sub-case of $k$-unit auctions, and gives a $(p+1)$-approximation for environments with $p$-independent set system constraints.
Exploring thioalkynes potential in gold catalysis with a divergent reactivity manifold

THIODIV brings together the complementary expertise of Dr Nagnath More (NM, expertise in oxidative reactions and arylation processes) with Dr Paul Davies (Host, expertise in gold catalysis and sulfur-based reaction development). 
Gold catalysis attract significant international interest due to its ability to generate metal carbene character from alkynes delivering more sustainable synthesis. Current strategies to address the major challenge of site-selective carbene formation use terminal alkynes, or those with strongly electron-donating- or electron-withdrawing groups. Limitations derive from the gold carbenes environment and its impact on reactivity, or the incorporation of undesired directing groups. THIODIV will study the potential of sulfur-substitution to deliver complementary directing effects while introducing a desirable functional group into the resulting molecule.  Preliminary studies show that sulfur can enable gold-catalysed reactivity, yet propose different directing-modes which lead to different regiocontrol. The overall aim of THIODIV is to examine the role of sulfur substitution on alkynes in gold catalysis and clarify its influence on reactivity, and hence allow wider application of sulfur-directing groups in gold catalysis and synthesis more widely. 
A diversity-generating dynamic reaction manifold will be used to elucidate key control parameters by studying two approaches, an oxidative rearrangement, and an arylative rearrangement. Alongside insight into reaction control and directing effects, THIODIV will provide new and efficient access to motifs that are featured in numerous bioactive compounds and are highly desirable in industry and academia as synthetic intermediates. While addressing fundamental questions of reactivity and control, THIODIV will also equip NM with the skills to incorporate hit- and lead-like properties into structure-reactivity studies to deliver new molecular entities that are applicable in pharmaceutical discovery.
Correlación de la aplicación de la escala de huang y la extensión vena cava inferior a la ecosonografía fast del servicio de Cirugia General del Hospital “Dr Luis Razetti” de Barinas 2012-2014

Correlación de la aplicación de la escala de Huang y la extensión vena cava inferior a la ecosonografía Fast, para determinar indicación quirúrgica en traumatismo abdominal cerrado, entre el periodo comprendido de marzo del 2013 a marzo del 2014. Se realizó un&nbsp; estudio prospectivo, observacional, analítico, transversal, en la sala de emergencia y quirófano del Hospital General Dr. Luis Razetti de Barinas. Un total de 200 pacientes con trauma abdominal cerrado a los que se les realizó ecografía Fast siendo negativo en 142 pacientes que representó el 71% de los casos, positiva en 58 pacientes, representando un 29% a este&nbsp; grupo se le aplicó el score de Huang y la medición de la vena cava inferior, obteniendo una puntuación de 1 a 2 en el 59% de los casos, con diámetro de la vena cava inferior entre 20 mm aproximadamente (no quirúrgicos ) y un puntaje mayor a 5 puntos con diámetro de vena cava menor de 10 mm en el 32% (quirúrgicos) y un 9 % se mantuvieron en observación durante 48 – 72 horas por presentar una puntuación entre 3 y 4 puntos y un diámetro de vena cava inferior entre 10 y 20 mm que no requirieron ser intervenidos quirúrgicamente , alcanzando con esto la comprobación de que los 39&nbsp; pacientes que representaron el 67% de los casos, se manejaron de manera conservadora, por los hallazgos de la prueba no requirieron ser intervenidos quirúrgicamente de inmediato ni posteriormente y fueron dados de alta satisfactoriamente. Conclusión: el empleo del FAST con escala de Huang y la extensión a la vena cava inferior ofrece una sensibilidad de un 100 % y una especificidad de 100 % , lo que demuestra que una modificación al score de Huang y la detección inmediata, en corto tiempo y no invasiva de un diagnóstico certero, facilitan la conducta terapéutica más adecuada para el manejo del paciente con traumatismo abdominal cerrado, rompiendo el paradigma de que todo paciente con liquido libre en cavidad debe ser llevado a mesa operatoria.
An IQ Domain Mediates the Interaction with Calmodulin in a Plant Cyclic Nucleotide-Gated Channel

Cyclic nucleotide-gated channels (CNGCs) form non-selective cation entry pathways regulated by calmodulin (CaM), a universal Ca(2+) sensor in eukaryotes. Although CaM binding has been shown to be important for Ca(2+)-dependent feedback regulation of CNGC activity, the CaM-binding properties of these channels have been investigated in a few cases only. We show that CNGC20 from Arabidopsis thaliana binds CaM in a Ca(2+)-dependent manner and interacts with all AtCaM isoforms but not with the CaM-like proteins CML8 and CML9. CaM interaction with the full-length channel was demonstrated in planta, using bimolecular fluorescence complementation. This interaction occurred at the plasma membrane, in accordance with our localization data of green fluorescent protein (GFP)-fused CNGC20 proteins. The CaM-binding site was mapped to an isoleucine glutamine (IQ) motif, which has not been characterized in plant CNGCs so far. Our results show that compared with the overlapping binding sites for cyclic nucleotides and CaM in CNGCs studied so far, they are sequentially organized in CNGC20. The presence of two alternative CaM-binding modes indicates that ligand regulation of plant CNGCs is more complex than previously expected. Since the IQ domain is conserved among plant CNGCs, this domain adds to the variability of Ca(2+)-dependent channel control mechanisms underlining the functional diversity within this multigene family.
First-principles prediction and partial characterization of the vibrational states of water up to dissociation

Abstract A new, accurate, global, mass-independent, first-principles potential energy surface (PES) is presented for the ground electronic state of the water molecule. The PES is based on 2200 energy points computed at the all-electron aug-cc-pCV6Z IC-MRCI(8,2) level of electronic structure theory and includes the relativistic one-electron mass-velocity and Darwin corrections. For H2 16O, the PES has a dissociation energy of D0 = 41 109 cm−1 and supports 1150 vibrational energy levels up to 41 083 cm−1. The deviation between the computed and the experimentally measured energy levels is below 15 cm−1 for all the states with energies less than 39 000 cm−1. Characterization of approximate vibrational quantum numbers is performed using several techniques: energy decomposition, wave function plots, normal mode distribution, expectation values of the squares of internal coordinates, and perturbing the bending part of the PES. Vibrational normal mode labels, though often not physically meaningful, have been assigned to all the states below 26 500 cm−1 and to many more above it, including some highly excited stretching states all the way to dissociation. Issues to do with calculating vibrational band intensities for the higher-lying states are discussed.
Effects of the two-component measurement error model on X control charts

The statistical properties of Shewhart control charts are known to be highly sensitive to measurement errors. The statistical model relating the measured value to the true, albeit not observable, value of a product characteristic, is usually Gaussian and additive. In this paper we propose to extend the said model to a more general formulation by introducing the two-component error model structure. We study the effects of the proposed error-model on the performance of the mean control charts, since gauge imprecision may seriously alter the statistical properties of the control charts. In order to take measurement errors into account in the design of the control charts we explore the use of different methods based on a weighted variance concept, a skewness correction method and an empirical reference distribution approach respectively. The different approaches are discussed and compared by Monte Carlo simulation. Results indicate that the last two methods produce the best results.
Functional role of epithelial–to–mesenchymal transition in the pathogenesis of inflammatory bowel disease

Inflammatory bowel disease (IBD) defines a group of chronic inflammatory disorders of the digestive tract, with ulcerative colitis and Crohn’s disease being its two major clinical manifestations, affecting 2.5 million people in Europe. The high prevalence of IBD in Europe and the multiple clinical challenges associated with a significant degree of unresponsiveness to anti-inflammatory therapies and development of complications requiring surgical intervention demand a deeper understanding of the cellular and molecular mechanisms underpinning IBD.
This project aims to understand the role of the process termed Epithelial–to–Mesenchymal Transition (EMT), an embryonic cellular trans-differentiation program re-launched in many pathological conditions, in the pathogenesis of IBD. EMT has in fact been detected in the inflamed intestinal mucosa and surrounding fibrotic areas of IBD patients and experimental models of colitis, however whether EMT functionally contributes to the pathogenesis of IBD is poorly understood.
The INFLEMT project aims to: 1) profile EMT in human IBD to identify its cellular features and correlation with the disease stage; 2) elucidate the impact of EMT on the integrity, functionality and regenerative capacity of the intestinal epithelial barrier; 3) explore the effects of EMT on fibrosis development and modulation of the immune response to assess its role in sustaining the chronic intestinal disease. 
These objectives will be pursued by utilizing patient-derived biopsies as well as novel mouse models to manipulate EMT in the intestinal epithelium. Comprehensive analysis, including RNA-sequencing and multispectral imaging, of the involved cellular and microenvironmental components (epithelial barrier, immune cells, fibroblasts) will be performed in acute and chronic colitis settings to mechanistically configure EMT as an epithelial injury response and a major functional driver in the pathogenesis of IBD.
Prepayment systems.

A prepayment system for controlling the supply of electricity, gas or water to a consumer comprises a metering or timing unit having a receptacle for receiving a prepayment token in the form of a key having a memory containing credit data. The metering or timing unit permits the supply of the commodity until the credit represented by the credit data in the key memory is exhausted. The system is provided with a push-button operated emergency supply facility, which permits the supply to continue for a predetermined time, typically four or five days, after the credit is exhausted. <IMAGE>
The “bookless” curriculum and the academic library

Purpose – The purpose of this column is to examine the concept of the electronic or “bookless” curriculum and the role the library can play in this evolving environment. Design/methodology/approach – This is a literature review and commentary on this topic that has been addressed by professionals, researchers and practitioners. Findings – In the all-electronic or bookless environment, the librarian's role still remains an essential one of supplementary instruction where teaching is paramount to the academic librarian's responsibilities. Whether providing expert research assistance or bibliographic instruction with the aim of imparting the student with the proper intellectual reinforcement, that role is not altered by any shift away from print. Originality/value – The value in addressing this issue is to support the discussion of this topic and provide the library and its librarians a motivation to rely upon during this shift.
(12057.23072018.164000140) NEW ETRURIA INTERNATIONAL

THE NEW TANNERY ETRURIA SRL HAS BEEN OPERATING FOR OVER TWENTY YEARS IN THE TANNING SECTOR OF LEATHER IN GENERAL. THE COMMERCIAL OBJECTIVE OF THE PROJECT? TO STRENGTHEN ITS POSITION IN ASIAN MARKETS, PARTICULARLY IN VIETNAM AND HONG KONG. TO DO IT? HAS THE COMPANY PARTICIPATED IN RECENT YEARS AND HAS IT ALREADY? IT IS EXPECTED TO PARTICIPATE IN INTERNATIONAL TANNING TRADE FAIRS IN ITALY AND ABROAD.
High-pressure cleaning device.

1. A high-pressure cleaning apparatus with an internal combustion engine (1) which, via transmission means, drives a high-pressure pump (3) whereby a cleaning fluid is delivered under pressure to a spray device (33), characterised in that the high-pressure pump (3) is arranged on the engine (1) in such a way that the output shaft (2), or an extension thereof, of the internal combustion engine (1) projects into the housing (4) of the high-pressure pump (3) ; in that a gap (6) is present between the internal combustion engine (1) and the pump housing (4), and in that a belt pulley (17), non-rotatably connected to the output shaft (2) of the engine, is arranged in this gap (6), which pulley drives an electrical generator (21) via a transmission belt (18).
Creating original knowledge in and for the workplace: evidence from a practitioner doctorate

The workplace is becoming acknowledged, if not without some contention, as a site of knowledge production that can have equal validity with academic and other research-oriented contexts. One way of investigating practice-based knowledge generation is through doctoral work that is based on research and development in the workplace. Examination of a selection of outputs from a doctorate geared specifically to work-based candidates confirms the workplace as a site of valid knowledge production, and also indicates that real-life projects concerned with development and change rather than explicitly with research can, if pursued with intellectual rigour and critical reflection, be a powerful source of new knowledge.
RURAL-URBAN MIGRATION AND UNEMPLOYMENT: THEORY AND POLICY IMPLICATIONS*

We develop a regional model where, in the city, unemployment prevails because of too high (efficiency) wages, while, in the rural area, workers are paid at their marginal productivity. We characterize the steady-state equilibrium and show that it is unique. We then consider two policies: decreasing urban unemployment benefits and subsidizing urban employment. We find that decreasing the unemployment benefit in the city creates urban jobs and reduces rural-urban migration since new migrants have to spend some time unemployed before they can find a job in the city. On the other hand, raising employment subsidies increases urban employment but may also increase urban unemployment because it triggers more rural-urban migration. In this respect, the employment subsidy policy can backfire by raising rather than reducing urban unemployment.
Enhancement of Rural Women Employment through Shg-Bank Linkage Strategy in Andhra Pradesh

In India, productive employment is central to poverty reduction strategy and to bring about economic equality in the society. But the results of unfettered operation of market forces are not always equitable, especially in India, where some groups are likely to be subjected to disadvantage as a result of globalization. Women constitute one such vulnerable group. In this context, there is a need to give importance in addressing the issue of inclusive growth of India from the banking perspectives. The concept inclusion should be seen as a process of including the excluded as agents whose participation is essential in the very design of the development process and not simply as welfare targets of development programmes. Growth is inclusive when it creates economic opportunities along with ensuring equal access to the women. Apart from addressing the issue of inequality, the inclusive growth may also make the poverty reduction efforts more effective by explicitly creating productive economic opportunities for the poor and vulnerable sections of the society. Self-Help Group Bank Linkage Strategy is taken as a key strategy for addressing both poverty alleviation and women's empowerment. The government of Andhra Pradesh has become a role model initiating this programme more effectively when compared to other regions. The main objective of the study is to examine the impact of SHG bank linkage strategy on occupation, employment and income patterns of rural poor women in Andhra Pradesh. A multi stage random sample method is used for the purpose of the study. Totally two hundred sample women SHG respondents were interviewed for the purpose of the study with a well structured questionnaire through schedule method. The study finally reveals that there is a positive impact of SHGs on creation of economic activity, employment and income generation of the rural poor women SHG members in Andhra Pradesh.