SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Acute Exposure to Di(2-Ethylhexyl) Phthalate in Adulthood Causes Adverse Reproductive Outcomes Later in Life and Accelerates Reproductive Aging in Female Mice

Humans are ubiquitously exposed to di(2-ethylhexyl) phthalate (DEHP), which is an environmental toxicant incorporated in consumer products. Studies have shown that DEHP targets the ovary to disrupt essential processes required for reproductive and nonreproductive health. Specifically, 10-day exposure to DEHP accelerates primordial follicle recruitment and disrupts estrous cyclicity in adult mice. However, it is unknown if these effects on folliculogenesis and cyclicity following acute DEHP exposure can have permanent effects on reproductive outcomes. Further, the premature depletion of primordial follicles can cause early reproductive senescence, and it is unknown if acute DEHP exposure accelerates reproductive aging. This study tested the hypothesis that acute DEHP exposure causes infertility, disrupts estrous cyclicity, alters hormone levels, and depletes follicle numbers by inducing atresia later in life, leading to accelerated reproductive aging. Adult CD-1 mice were orally dosed with vehicle or DEHP (20 μg/kg/day-500 mg/kg/day) daily for 10 days, and reproductive outcomes were assessed at 6 and 9 months postdosing. Acute DEHP exposure significantly altered estrous cyclicity compared to controls at 6 and 9 months postdosing by increasing the percentage of days the mice were in estrus and metestrus/diestrus, respectively. DEHP also significantly decreased inhibin B levels compared to controls at 9 months postdosing. Further, DEHP significantly increased the BAX/BCL2 ratio in primordial follicles leading to a significant decrease in primordial and total follicle numbers compared to controls at 9 months postdosing. Collectively, the adverse effects present following acute DEHP exposure persist later in life and are consistent with accelerated reproductive aging.
Survie des patients en oncologie traités par l’équipe de soins palliatifs d’un hôpital de São Paulo, au Brésil

Introduction : L’échelle de l’indice fonctionnel de Karnofsky (Karnofsky Performance Status Scale) est un instrument d’évaluation pertinent et fonctionnel qui sert à déterminer quelles personnes devraient être suivies par des équipes multidisciplinaires de soins palliatifs. Objectif : Analyser les résultats cliniques de patients, suivis par une équipe de soins palliatifs, dont l’indice fonctionnel de Karnofsky est inférieur à 70 %, et les comparer aux résultats de personnes n’ayant pas bénéficié de ce type de soins. Méthodologie : Dans la présente étude de cohorte rétrospective, le suivi pendant 10 jours des patients par l’équipe de soins palliatifs constituait le facteur d’exposition et la survie, la variable dépendante. Des données ont été extraites des dossiers médicaux afin de réaliser des statistiques descriptives et des analyses des courbes de survie. Résultats : Parmi les 581 participants de l’échantillon, 42,5 % avaient des métastases. Le cancer gastro-intestinal était le diagnostic plus prévalent (29,1 %). Du groupe, 51 participants (8,7 %) étaient suivis par l’équipe de soins palliatifs. Le taux de mortalité pendant les 10 jours de suivi s’élevait à 10,8 %; il était plus élevé encore (15,7 %) chez les patients suivis par l’équipe de soins palliatifs. Conclusion : Les patients ayant un indice fonctionnel inférieur à 70 % qui étaient suivis par l’équipe de soins palliatifs présentaient un piètre état clinique et une période de survie plus réduite comparativement aux autres patients. Mots-clés : soins palliatifs, personnes atteintes de cancer, indice fonctionnel de Karnofsky, analyse du taux de survie
INOVAÇÃO DE UMA MISTURA ÚNICA DE GESSO

O tema do projeto é a inovação de produtos da Klinosan e a inovação de processos relacionados com a produção em larga escala do produto. É uma mistura única de gesso que tem efeitos antifúngicos e antibacterianos muito fortes e pode absorver substâncias cancerígenas. A transferência de tecnologia terminou com a concessão de um modelo de utilidade foi realizada em cooperação com a TUL e a VŠCHT. Local de execução do projeto: Třídvorská 108, 784 01 Červenka
European magnesium interactive battery community

Energy storage is a key technology to facilitate a widespread integraWith the growing use of intermittent energy sources in power grids, there is a growing mismatch between when energy is produced and when it is consumed. This has led to the need of energy storage or demand-response systems in order to use the energy in a balanced and efficient way. Given this context, the Micro Energy Storage (MES) systems are expected to seek radically new approaches to supply energy where it is needed. Buildings are becoming a local use micro energy-hubs consuming, producing, storing, supplying energy and having the potential to take up an important role in the power-supply system stability which generate energy with renewables, provide storage for electric and thermal energy and deliver demand response. For Micro Energy Storage in Buildings (MESB) using stochastic renewables energy, the most suitable technology is the lithium-ion batteries (LIB). However, current LIB technologies are facing severe challenges in safety, energy density and price. While most of today's R&D is concentrated on LIB systems, shifting towards non-lithium rechargeable batteries may open up effective ways to overcome such challenges. The rechargeable magnesium battery (RMB) constitutes a paradigmatic example of such promising, alternative non-lithium energy storage systems, following pioneering efforts and breakthroughs from world-wide researchers. The potential to use metallic magnesium anodes in rechargeable batteries brings important advantages in terms of energy density, cost and safety. E-MAGIC gathers the key scientific and technical researchers in Europe to develop the required new frontier knowledge and foundational approaches on RMB, bringing an effective work on R&D by a rational design of high voltage/high capacity cathode materials and novel electrolytes to overcome the rate-limiting reaction and transport processes, in order to deliver a safe RMB with more 400 Wh kg-1 and less than 100 €/Kwh.
Analysis of the clinical utility of gene expression profiling in relation to conventional prognostic markers in South African patients with breast carcinoma

s Published Grant KA, Apffelstaedt JP, Wright CA, Myburgh E, Pienaar R, de Klerk M, Kotze MJ (2012) Development and implementation of the MammaPrint Algorithm (MPA) to reduce chemotherapy overtreatment in South African patients with early stage breast cancer. Histopathology 61(1): 20-21 Grant KA, Apffelstaedt JP, Wright CA, Myburgh E, Pienaar R, de Klerk M, Kotze MJ (2013) MammaPrint® Prescreen Algorithm (MPA) reduces chemotherapy in South African breast cancer patients. The Breast 22S1: S92 Grant KA, Cronje FJ, Botha K, Apffelstaedt JP, Kotze MJ (2013) Development of a genetic database resource for monitoring of breast cancer patients at risk of physical and psychological complications. South African Journal of Psychiatry, Vol 19, Issue 3: 91-126 Stellenbosch University http://scholar.sun.ac.za
European Pulsar Timing Array limits on continuous gravitational waves from individual supermassive black hole binaries

We have searched for continuous gravitational wave (CGW) signals produced by individually resolvable, circular supermassive black hole binaries (SMBHBs) in the latest EPTA dataset, which consists of ultra-precise timing data on 41 millisecond pulsars. We develop frequentist and Bayesian detection algorithms to search both for monochromatic and frequency-evolving systems. None of the adopted algorithms show evidence for the presence of such a CGW signal, indicating that the data are best described by pulsar and radiometer noise only. Depending on the adopted detection algorithm, the 95\% upper limit on the sky-averaged strain amplitude lies in the range $6\times 10^{-15}<A<1.5\times10^{-14}$ at $5{\rm nHz}<f<7{\rm nHz}$. This limit varies by a factor of five, depending on the assumed source position, and the most constraining limit is achieved towards the positions of the most sensitive pulsars in the timing array. The most robust upper limit -- obtained via a full Bayesian analysis searching simultaneously over the signal and pulsar noise on the subset of ours six best pulsars -- is $A\approx10^{-14}$. These limits, the most stringent to date at $f<10{\rm nHz}$, exclude the presence of sub-centiparsec binaries with chirp mass $\cal{M}_c>10^9$M$_\odot$ out to a distance of about 25Mpc, and with $\cal{M}_c>10^{10}$M$_\odot$ out to a distance of about 1Gpc ($z\approx0.2$). We show that state-of-the-art SMBHB population models predict $<1\%$ probability of detecting a CGW with the current EPTA dataset, consistent with the reported non-detection. We stress, however, that PTA limits on individual CGW have improved by almost an order of magnitude in the last five years. The continuing advances in pulsar timing data acquisition and analysis techniques will allow for strong astrophysical constraints on the population of nearby SMBHBs in the coming years.
Jos, the first electrified energy surface with high efficiency, high power and high energy savings for the wireless charging of all low voltage devices.

JOS is the first Energy Surface with high-power and energy efficiency, a patented lighting and charging device system. It’s a
low-voltage electrified panel, on which it’s possible to feed any electronic device without any cables, in numberless position
and with an energy saving of up to 25% compared with traditional systems.
JOS can also be powered with direct photovoltaic and it’s extensible in series even on very large areas, so to use a single
power supply and protect the environment.
All spaces fed with JOS will enjoy a strong reduction of electromagnetic emissions. The panel has the virtue of thermal
insulation and sound absorption, exploitable in the context of inner installation.
JOS technology offers a very different technology and is characterized by: INTEGRATION of all types of devices, HIGH
POWER (100 W per connection), FLEXIBILITY in positioning (table, wall, ceiling), ENERGY SAVING, CUSTOMIZATION
(functional and design).
JOS is not just a product but a technology with a double value proposition, both B2C and B2B. JOS B2C - Consumer
Electronics, huge market. PLUS: integration, savings, flexibility, elimination of wires.
JOS B2B - Great alternative or integration to traditional installation - panels of custom formats, extensible in series with
specific devices. PLUS: reduction of time and costs in all phases, no longer traces or wiring, or structural interventions for
changes, electromagnetic healthiness, energy saving.
A technology adaptable to many different contexts, including disability, multiplying and simplifying the access to energy, with
a strong facilitation of social and working conditions.
Because JOS is a system with many possible applications, the feasibility study will be particularly aimed at the study of
various business models, according to the different contexts and at detailed analysis of the various markets.
The first true answer to avoid the need of CO2 polluting batteries in the near future.
UOCR: A ligature based approach for an Urdu OCR system

Optical Character Recognition (OCR) system translates text images into digitally editable text files. There exist OCRs for different languages but developing an OCR for Urdu is a challenging task because of its cursive nature and context sensitivity. This is the main reason behind very limited work on very Urdu OCRs systems, and the previous works on Urdu OCR are not very efficient in converting the image text file into editable text files. In this paper, we have proposed a UOCR system for converting printed Nastalique Urdu Script image file into digitally editable text files. It takes printed Nastalique Urdu image file as input and after performing operations like binarization, segmentation, feature extraction and classification on that document, it finally produces digitally Urdu editable text files as output. We are using SIFT and SURF methods for computing descriptor in our feature extraction approach. Our proposed UOCR system is-very efficient in conversion.
New generation of high thermal efficiency components packages for space

HEATPACK project aims to develop and validate critical technology building blocks for enabling transformative packages for space applications with very low thermal resistance. This is to fully exploit the potential of wide-bandgap technologies which are now being considered as critical in numerous sectors and for space applications in particular, as enhanced thermal management solutions beyond state-of-the-art need to be provided. Benefits will range from improved performance to increased components reliability and lifetime. HEATPACK concepts for achieving high power / high thermal efficiency packages include: 
- Diamond based composite materials with a thermal conductivity >600W/m.K to be used as baseplate or insert 
- Silver sintering based Thermal Interface Material (TIM) for components assembly  
- TIM for package to structure assembly with both electrical and thermal enhanced properties (in excess of 10W/m.K) 
- Innovative cooling solutions with strategic implementation possibilities (baseplate, lid, structure…). Using these technologies, two different modules implementing Gallium Nitride (GaN) components will be developed:   
-A power supply switching module based on a multilayer ceramic substrate 
-A Ka-band High Power Amplifier based on a surface mount hermetic micro package. 
The main applications targeted are satellite’s output power section for telecommunication missions in particular, as well as power conditioning / power supply units concerning all satellite payload’s equipment consisting of high power supplies. 
To secure a fully European supply chain for high power components thermal management, the technologies developed will reach a TRL of 6, demonstrating commercial viable solutions providing reliability levels compliant with space environments.
Arbuscular mycorrhizal root colonization and soil P availability are positively related to agrodiversity in Mexican maize polycultures

In Los Tuxtlas, Mexico, the local Popoluca people maintain the traditional management of their maize agroecosystems. However, it is not known whether the loss of agrodiversity over recent decades has affected mycorrhizal populations, nutrient availability, and crop productivity. This study utilized linear mixed effect models to analyze the relationship between agrodiversity (three, six, and greater than or equal to eight cultivated species) and (a) arbuscular mycorrhizal fungi (AMF) inoculum potential, measured as the most probable number (MPN) of propagules and colonization level, (b) nutrient availability, and (c) aboveground maize productivity. We also investigated the relationship between soil nutrient content and inoculum potential. Soil samples were taken before planting, and during flowering, in the 2009 maize cycle. We found that AMF colonization level of maize roots and P availability increased with planted species richness, but that this effect only occurred at the flowering sampling date. Plots with a higher MPN of propagules presented increased C and NO
 3
 −
 contents and lower C/N ratio than those with lower MPN of propagules, regardless of agrodiversity. Soils that produced the highest maize root colonization level also featured high P availability and N content. We conclude that decreased agrodiversity in these traditional systems does not significantly affect the soil MPN of propagules, but may have a negative impact on the ability of the mycorrhizal community to colonize maize roots, as well as reducing the availability of P, which is often the most limiting nutrient in tropical soils.
Fundamental physics using black widow, redback and transitional pulsar binaries

I will use an innovative coupled approach to facilitate a paradigm shift in the use of neutron stars as a probe of high energy physics. The compactness, rapid rotation and large magnetic fields of neutron stars make them, along with black holes, the most extreme objects found in our Universe. Neutron stars are therefore formidable laboratories to study fundamental physics, as they allow us to probe regimes simply unavailable to Earth-based experiments. However, in spite of their potential utility, there are still a number of important outstanding questions in this field. Key amongst these are: What is the neutron star equation of state?  How do neutron stars become the fastest rotating stellar objects in the Universe? How do millisecond pulsars affect their environment? Answering these questions has a broad multi-disciplinary impact, far beyond the field of neutron star research alone; however, at present our ability to answer these questions is limited by cherry picking individual objects for study. In this proposal I describe how I will move away from the biases inherent in the idiosyncratic nature of particular sources to a comprehensive population analysis, and specifically, how I will use a particular class of neutron star systems, known as “spider binaries”, to discover the most massive and the fastest spinning neutron stars that exist. Such extreme cases are of crucial importance for constraining the neutron star equation of state and thus determining the boundary for stellar mass black hole formation. This knowledge in turn can tell us about possible phase transitions of matter at high densities and provide observable quantities that can then be tested against Earth-based experiments, feeding back into high energy physics theories. I will achieve these goals through a transformational observational approach to finding new spider systems and drawing on innovative techniques from other fields to improve parameter estimation.
Enhancing cadastral surveys by facilitating the participation of owners

AbstractWhile some countries have over centuries developed a nation-wide spatial framework, some others have been left behind. However, because of the global economic and social challenges, there is an urgent need for those countries to develop similar systems in a fast and efficient way for their economic survival. Building such a framework should be always based on each country's resources and capacities. In systematic cadastral registrations, the participation of owners has always been crucial for the success of the project. Within this concept, the authors investigate the potential of new tools to increase the participation of land right holders and local volunteers (non-professionals) and to enhance the cadastral surveying procedure. A hybrid “crowdsourcing” approach is proposed, mainly based on the direct participation of property rights holders in which the role of the cadastral surveyor is crucial. A commercial application for smartphones is tested. The smartphone's GPS is used only for the genera...
DOTMP KIT FORMULATIONS FOR RADIOISOTOPES

This invention relates to a Kit formulation to prepare a radioactive, bone-seeking, pharmaceutical drug that has high radiochemical purity (RCP) in a fast, facile and reproducible process. The Kit has at least two vials and a two part buffer system with instructions on how to make the drug formulation in a radiopharmacy. The drug formulations of this invention can be conveniently and reproducibly prepared with better delivery of the drug to mammals, better radiochemical purity of the formulation for use in treating a mammal having bone pain, one or more calcific tumors or needing bone marrow suppression.
Signal Acquisition Analysis in Hi-Speed and Hi-Precision MFL Testing for Steel Pipe

Dealing with the relationship properly between the sensor scanning and signal acquisition is the base of hi-speed and hi-precision MFL (magnetic flux leakage) testing for steel pipe. Firstly, the MFL wave form characteristic was established using magnetic dipole theory. Further, on that basis, the relationship between signal frequency and sensor scanning was analyzed. Finally, sample frequency was designed according to the requirement of the automatic steel pipe MFL testing. Additionally, the MFL signal acquisition experiment was conducted to verify the influence of the signal sampling frequency. The signal acquisition analysis was of great significant to perform the MFL testing for steel pipe in hi-speed and hi-precision.
The optimal asset and liability portfolio for a financial institution with multiple lines of businesses

In this paper we present an optimization framework to deal with the asset-liability portfolio selection problem. We consider a financial institution that has multiple lines of business. The capital allocation is obtained by minimizing the sum of the expected squared differences between the liability in each line of business and the value of the corresponding investment portfolio. We show that in certain circumstances the bottom-up approach is consistent with the top–down approach, where the optimal capital is determined for the whole portfolio rather than its individual components. Such a case happens for example if the same weight function is used for all lines of business in the two approaches. Finally, we obtain investment portfolios under some limitations on short sales.
PROCESS AND PLANT FOR TREATING WASTEWATER CONTAINING MICROPOLLUTANTS OF PHARMACEUTICAL ORIGIN

A completely biological process for eliminating a first group of micropolluants of pharmaceutical origin and a second group of micropolluants of pharmaceutical origin in wastewater and plant for the implementation of the process, the process comprising the steps of: - in a first treatment, introducing the wastewater (1), once screened, into the moving-bed membrane bioreactor (MB-MBR) (11) populated by first microbial consortium for a first retention time; - in a second treatment, introducing the wastewater (1) treated by the bioreactor (11) into the biofiltration tank (12), different from the tank of the bioreactor, comprising one or more biologically activated carbon (BAC) columns and leaving the residues of micropolluants of pharmaceutical origin to be absorbed on the active carbon; - leaving the active carbon that has previously absorbed the residues of micropolluants of pharmaceutical origin to be colonized by the second microbial consortium in the form of biofilms for a second retention time; the total hydraulic retention time, consisting of the sum of the first retention time and the second retention time, being determined in order to obtain an average purifying efficiency (R) for the micropolluants of pharmaceutical origin of the first group in the treated wastewater (2) of greater than 80%, preferably of greater than 95%, and an average purifying efficiency for the micropolluants of pharmaceutical origin of the second group of greater than 40-50%, with reference to the content (Co) thereof in the initial wastewater (1).
Search for a SM Higgs boson in theH→Z*Z→ ℓ+ℓ−qq̅channel in the mass range 120 - 180 GeV with the ATLAS Detector at √s= 7 TeV

A summary of the first study is given for the decay channel H ! Z ⇤ Z ! ` + `q¯ q (` = e,µ) in the Higgs boson mass range 120 - 180 GeV, using the pp collision data collected by the ATLAS experiment at p s = 7 TeV at the LHC. Data driven methods to estimate the background and new techniques to improve the mass resolution of the hadronic Z boson decay are used. Events with 0 or 1 b-jets and events with 2 b-jets are treated as separated channels. No significant excess of events above the estimated background is observed; upper limits at 95% C.L. on the Higgs production cross section are derived.
FAULT DETECTION AND DIAGNOSIS

THE PROJECT INVOLVES THE PURCHASE OF SOFTWARE/HARDWARE FOR REMOTE SYSTEM MONITORING IN ORDER TO LIMIT THE MOVEMENT OF STAFF LINKED TO THE SERVICE.