SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Seroprevalence of Dengue in Gujarat, Western India: A study at a tertiary care hospital

Background: Dengue is one of the most serious mosquito borne viral infection mainly affecting tropical and subtropical countries of the world. In absence of specific treatment and vaccine for dengue fever (DF); vector control is the only method by which the spread of dengue can be prevented.

Aims & Objective: This study was conducted to report the prevalence of Dengue virus infection in Gujarat, Western India.

Material and Methods: Study was performed at a tertiary care hospital in Ahmedabad, Gujarat in year 2012. Patients attending various hospitals across Gujarat for suspected dengue were tested. Blood samples collected in plain tubes were tested for dengue IgM antibodies, NS1 antigen and viral nucleic acid detection by Dengue IgM capture enzyme linked immune sorbent assay, Dengue Early ELISA and real time reverse transcriptase PCR, respectively. The laboratory records were analyzed for demographic features and seasonal variations. Descriptive statistics were used. Data were expressed in proportions.

Results: Out of total 4401 serum samples tested, 927 were found positive for dengue virus infection. 65% positive samples were of male patients and 58% positive samples were from 18 to 35 years age group (Adult population) (58%). Seasonal trend showed a gradual increase in dengue positives started from August with a peak in October (34.5%). The most common presentation was fever (97%) while only 1% cases presented haemorrhagic manifestations.

Conclusion: Dengue has established its transmission in urban and semi-urban areas of Gujarat with predominantly affecting males and active adult population. Virus activity is high during monsoon and post monsoon period which coincides with increased vector breeding. This study thus emphasizes the need for continuous sero epidemiological surveillance for the timely formulation and implementation of effective dengue control programme.
Space Environmental Testing of Novel Candidate Materials for Multilayer Insulation

Multilayer insulation forms the outer barrier of a satellite towards space. Polymer foils used in multilayer insulation have to withstand the space environment for mission durations often lasting well above 10 years. This paper outlines the space environmental test campaign performed to qualify novel and advanced polymer foils to reduce blanket mass and replace export-controlled materials. Complete multilayer insulation layups were irradiated; these were composed of thicker outermost layers of the reference material Kapton®, a white polyimide and an alternative, conductive black polyimide and up to seven thin internal, aluminized 6  μm or 3  μm polyethylene terephthalate and polyethylene naphthalate layers separated by nonwoven spacers. One sample set consisted of 25  μm polyether-ether-ketone foil and 6  μm internal vacuum-deposited-aluminum-coated polyether-ether-ketone layers. Materials were exposed to ultraviolet, electrons and protons simulating a 15-year geostationary orbit mission. Absorptance was ...
Equivalent waveband selection of VIS-NIR spectroscopic measurement for hemoglobin

The VIS-NIR spectroscopy combined with the improved Moving Window Partial Least-square(MWPLS) method was applied to a high accurate waveband selection for the rapid no-reagent determination of Hemoglobin(HGB) in human whole blood.A new modeling evaluation system was proposed to avoid the evaluation distortion.First,seventy samples were randomly selected from a total of 205 samples as the validation set,the remaining 135 samples were used as the modeling set,and the modeling set was divided into similar calibration(80 samples) and prediction(55 samples) sets for a total of 50 times.Then,modeling and optimization were performed in each division to get stable model.Finally,the optimized model was validated again using the validation set.Experimental results indicate that the VIS-short NIR region 400-1 100 nm can be used as the information waveband of HGB in human whole blood,the global optimal waveband 492-890 nm is further selected from 400-1100 nm with MWPLS method,and a model space including 77 equivalent wavebands is obtained.By taking the 492-890 nm for an example,validation effects V-SEP,V-RP,and V-RSEP are 2.58 g L-1,0.988,and 1.97%,respectively.It concludes that HGB prediction values of the samples are highly close to the clinic measured values,which may be used in clinical diagnosis.
Aicraft design and noise rating for regional aicraft

Aicraft Design and nOise RatiNg for regiOnal aicraft. 
The activities related to the ADORNO project are focused on the development of aircraft models for a regional aircraft engine platform. The main objective is to provide aircraft requirements (e.g.  thrusts,  offtakes,  etc.) as well as trade factors for specific fuel consumption, engine drag and engine weight on fuel burn for both a year 2000 reference aircraft and a CS2 target aircraft. In addition, an aircraft noise method will be developed and integrated in an aircraft design chain.
The high-level objective of ADORNO is to allow a fast and reliable estimation of aircraft Noise and emissions in terms of CO2, NOx at different mission phases, through the implementation of a flexible aircraft model which provides requirements for the engine platform in terms of thrusts and offtakes at different power settings and flight conditions.
The ADORNO high level objective is translated into the following main technical objectives:
• To deeply apply the available MDO chain for aircraft design with integration of noise, emission and engine tools.
• To implement a flexible A/C modeller which allows an easy integration of an external engine model to obtain an efficient and cost-effective design processes.
• To implement a stand-alone tool for noise prediction which required only few inputs and could be easily customizable by users. 
• To provide an emissions prediction tools which required only few inputs and could be easily customizable by users.
• To provide a concurrent design approach enhanced by integration of visualization tools to support the design team for the understanding of the product and its behavior during the design sessions.
Translational approaches to disease modifying therapy of type 1 diabetes: an innovative approach towards understanding and arresting type 1 diabetes – sofia ref.: 115797

Preclinical type 1 diabetes (T1D) research has made important advances in recent years, but less progress has been made in translating findings from in vitro and animal models into effective clinical interventions. INNODIA aims to achieve a breakthrough in the way in which we study T1D to enable us to move closer towards prevention and cure of T1D. To this end, INNODIA joins together the leading European experts from the fields of basic and clinical T1D research, four leading pharmaceutical companies with strong expertise in the discovery and development of diabetes medicines and the two leading public organizations involved in T1D research into one comprehensive collaborative consortium. The clinicians in INNODIA oversee T1D registries and have access to large populations of children and adults with T1D and family members at increased risk of developing the disease. The basic science researchers are experts in beta-cell pathophysiology, immunology, biomarker discovery, bioinformatics, systems biology and clinical trial design. INNODIA will accelerate understanding of T1D through coordinated studies of unique clinical samples and translation-oriented preclinical models. This should deliver novel biomarkers and interventions for testing in appropriately designed trials, to be developed in active collaboration with regulators and patients. INNODIA provides access to unique historical biorepositories and will create the Clinical Sample Network, a clinical EU infrastructure to recruit T1D subjects at diagnosis and at-risk relatives. These individuals will be deep-phenotyped and will provide biosamples, allowing the establishment of a ‘living biobank’ of subjects consented for recall. They will be characterized using standardized clinical, genetic and metabolic phenotyping procedures, including prospective, longitudinal sample collection to facilitate novel biomarker discovery. Diverse biological samples (blood, plasma, serum, urine, stools, etc.) will be collected at
Training the next generation of leaders to deliver innovations in dignified sustainable care systems for older people

INNOVATEDIGNITY is a trans-national network that aims to deliver a shared, world-leading research and training programme to educate the next generation of thought leaders with the necessary research experience and transferable skills to deliver innovations in dignified, sustainable care systems for older people, including new care models and digital applications. INNOVATEDIGNITY’s research examines older peoples' perspectives of care systems with a specific focus on dignity, investigates the potential for digital applications, and analyses gender issues to provide crucial, urgently needed knowledge for sustainable and fit for purpose care that supports older people to live well. The network's programme of investigation:  1) Critically evaluates existing care systems and provide analyses that make use of older persons’ insights. 
 2) Examines and offers a range of conceptual, empirical and methodological conditions to develop new innovations, including digital technology that offer dignity in care. 3) Provides an analysis of impacts of new care models on the wellbeing of older people. 4) Critically examines impacts of gender on care delivery, on the leadership of caring and science careers, and the care workforce with insights for sustainability. INNOVATEDIGNITY addresses the European problem of how ageing people can live well in caring systems with a concentration on cross-disciplinary scholarship, producing an evidence base through fifteen PhD projects, interlinked with a series of integrated assignments, and supported by a coherent interdisciplinary training. INNOVATEDIGNITY will produce leaders well versed in innovating care from standpoints within and beyond ‘healthcare’, sectors that engage technology, the public, policy makers for the benefit of older people in Europe beyond the consortium nations.
Observation of low shear wave velocity at the base of the polar ice sheets: evidence for enhanced anisotropy

SUMMARY
We analyse seismic data from the broad-band stations located on the Antarctic and Greenland ice sheets to determine the large-scale seismic parameters of the polar ice sheets. The P-to-S converted waves at the ice/rock interface and inside the ice sheets and their multiples (the P receiver functions) are used to estimate the in situ P velocity Vp and the P-to-S velocity ratio Vp/Vs of the polar ice. The thickness of the whole ice layer is precisely known either from radio echo soundings or from ice core drillings allowing thus an accurate determination of Vp and Vp/Vs. At some places in and near the Wilkes Basin, a sedimentary layer is probably squeezed between the ice and the bedrock. We find that the polar ice caps have a two-layer structure, the upper layer of variable thickness about 2/3 of the total thickness with velocities very close to the ice standard values and the lower layer preserving a standard Vp but with about 25 per cent smaller shear wave velocity and a more or less constant thickness. The shear-velocity drop in the lower layer may be the evidence of a strong anisotropy induced by preferred orientation of ice crystals and by fine layering of soft and hard ice layers. A large variation of ice viscosity with depth is therefore expected and heterogeneous flowing of the polar ice sheet. This heterogeneous flowing may invalidate the use at great depth of the ice dating models based on monotonic layer thinning.
XITI S.A.S. DI FIRRIOLO R. AND BELLANTONIO F.

THE MAIN PURPOSE OF THE COMPANY IS TO: — PROFESSIONAL ACTIVITY EXTIMO-TECHNICAL PURSUANT TO LAW 166/92, — CONSULTANCY, ASSESSMENT AND ESTIMATION IN THE FIELD OF INSURANCE, CIVIL AND INDUSTRIAL. THE ACTIVITY CARRIED OUT IN THE COMPANY CONSISTS ESSENTIALLY OF OFFICE ACTIVITIES WITH THE USE OF VIDEO TERMINALS AND ACCESSORIES (PRINTER, PHOTOCOPIER, TELEPHONES, ETC.). PART OF THE ACTIVITY IS ALSO OF A COMMERCIAL NATURE AND IS EXPRESSED IN THE RELATIONSHIP WITH CUSTOMERS AND IN THE HANDLING OF THE RELATED PRACTICES.
Showcasing synergies between agriculture, biodiversity and ecosystem services to help farmers capitalising on native biodiversity

The slow adoption by the agricultural sector of practices to promote biodiversity are thought to originate from three interrelated issues. First, we know little about which incentives effectively motivate farmers to integrate biodiversity into daily farm management. Second, few studies so far have produced evidence that biodiversity-based approaches produce benefits in terms of key variables for farmers (yield, profit). Third, there is a large communication gap between the scientists investigating biodiversity-based farming practices and the farmers that have to implement them. 

To overcome these barriers, SHOWCASE will review and test the effectiveness of a range of economic and societal incentives to implement biodiversity management in farming operations and examine farmer and public acceptance. Focus will be on three promising approaches: (i) result-based incentives, (ii) involvement in citizen science biodiversity monitoring and (iii) biodiversity-based business models. SHOWCASE will co-produce together with stakeholders a solid interdisciplinary evidence for the agro-ecological and socio-economic benefits of biodiversity management in 10 contrasting farming systems across Europe. SHOWCASE will also design communication strategies that are tailor-made to farmers and other key stakeholders operating in different socio-economic and environmental conditions. 

SHOWCASE will develop a multi-actor network of 10 Experimental Biodiversity Areas in contrasting European farming systems that will be used for in-situ research on biodiversity incentives and evidence for benefits as well as knowledge exchange. This network will be used to identify and test biodiversity indicators and targets relevant to all stakeholders and use them in a learning-by-doing approach to improve benefits of biodiversity management on farms both within the network and beyond.
Paving the way for farm animal welfare in international relations: an EU–Brazil case study

As a sensitive area in international trade, animal welfare measures have encountered resistance in negotiations at the World Trade Organization (WTO). Consequently, alternative avenues have been pursued to reach international trade policy convergence. To further understand the contemporary trade politics of animal welfare, an empirical investigation was conducted on the interplay between European and Brazilian actors in the context of livestock production. By drawing upon diplomatic studies and the global governance literature, this study identifies and analyses initiatives that parallel the WTO approach and through which the development and implementation of mutually acceptable farm animal welfare measures have been pursued. Research findings indicate that a constellation of international non-diplomatic actors are currently engaged in influencing the future development of farm animal welfare measures. Among the initiatives that enable the alignment of European and Brazilian animal welfare policies and pr...
Pollution Sources and Loads of Nitrogen and Phosphorus in Xinlicheng Reservoir of Changchun City

The analysis and quantification of nitrogen and phosphorus pollution sources is the base before managing the Xinlicheng Reservoir. To master the pollution sources and loads helps to take measures for improving the water quality. NH3-N and TP were the key pollutants resulted in deterioration of water quality by water environmental quality assessment method. The pollutants were from upstream flow and surrounding drainage of the reservoir. The surrounding drainage pollution sources consisted of point and non-point sources. The loads from upstream flow and surrounding drainage were estimated by mean concentration method and reservoir water quality model. The daily fluxes of ammonia nitrogen and total phosphorus in the snow-melting period and wet season were 1 708. 0 kg,255. 0 kg,and324. 7 kg,336. 8 kg into the reservoir,respectively. The input point source loads per day in snowmelting period and wet season were 30. 5 kg NH3-N,8. 3 kg TP,and 46. 3 kg NH3-N,47. 8 kg TP,respectively. And the input non-point source loads per day in the snow-melting period and wet season were 96. 7 kg NH3-N,6. 4 kg TP,and 36. 5 kg NH3-N,59. 2 kg TP,respectively. The pollution loads from the upstream of the reservoir was the key source. It is imperative to control the upstream water pollution and to reduce the surrounding pollution sources for the safety of drinking water source.
Interest of simultaneous Chlamydia trachomatis and Neisseria gonorrhoeae screening at the time of preabortion consultation

This study was conducted to estimate the prevalence and risk factors of Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) infection among women consulting for abortion and to discuss screening for these pathogens in this population.Systematic CT/NG screening using real-time polymerase chain reaction was performed on cervical samples from 421 women who consulted for abortion over a 6-month period.Among the 421 women included, 13 had symptoms of gynecological infection, and 408 were asymptomatic. Only one of the symptomatic women was infected with CT (7.7%), and none of the women were infected with NG. Among the asymptomatic women, 40 were CT infected (9.8%), and three were NG infected. The overall prevalence was 9.7% for CT infection and 0.7% for NG infection.This population had a high prevalence of CT infection and a low prevalence of NG infection. Most infections were asymptomatic, which could justify systematic simultaneous screening for these two pathogens.
Qseif: the new pathogen, dna and immunological testing platform

iMiCROQ aims to bring to the market the first integrated platform for pathogen, immumological and PCR testing specially
designed to cover the whole needs at farm level, internal control laboratories, food processors and point-of-care infectious
disease testing. Thanks to its affordability, QSEIF will allow from SMEs to large companies to improve their biosafety and
internal microbiology control to fulfil their requirements from ISO 22000, BRC or IFS certifications, while reducing the needs
in laboratory space, the investment, the test cost and man-hour involvement thanks to higher automation. Another important
breakthrough in the immunological sector is that QSEIF provides 1-2 orders of magnitude lower limit of detection, less time
and better dynamic range than current reference test ELISA. We envision three important applications of this disruptive
platform in the areas of: (1) Food Safety; (2) Vaccination Control; (3) Immunoassays for human and animal diagnosis. We
will reach end-users from all these sectors according to different commercial strategies that have been tailored to suit each
type of customer.
The main objective of this project is to increase the technical maturity of the platform and to validate its performance and
operability in operational environment with different end-users. After this 24 months project, we will lauch QSEIF to the
market with the aim of becoming an international reference in the diagnostic market. The viability of the technological,
regulatory, market and financial aspects of the QSEIF innovation project were assessed through a feasibility analysis carried
out in SME Instrument Phase I. From the analysis, we expect to install 717 devices that would perform 5.2M tests in a five
year period. By then, QSEIF platform will bring an accumulated Net Profit of 5,32M€ by 2024. It is expected that sales of
QSEIF will represent 40% of the company’s total revenue in 2021, growing to 88% by 2024.
Unravelling earth’s magnetic history and processes

We wish to understand how magnetic fields are generated in the cores of planets. This process is called the dynamo mechanism, whose understanding remains one of the geophysical grand challenges. In cores of rocky planets and in gas giants, thermal forcing results in convection and the resulting flow of liquid metal transports heat and generates magnetic fields as a result of the electrical currents that are induced by their motion. Magnetic field generation affects heat transport and cooling, controlling planetary history and evolution (on Earth it is connected with the growth of the inner core); and ultimately the presence or not of magnetic fields can control the existence of life. To understand the process, the momentum, induction and heat equations must be solved in three dimensions as a function of time in a spherical geometry and linked to the numerous extant data sets that are available. Present-day computer simulations do this by implementing fluid viscosities that are too large by many orders of magnitude. Our aim is to correct this by creating a working computer code that correctly implements a novel theory for the dynamo process in which viscosity and inertia have negligible effects, as is correct for the planets. These dynamos are likely to be different from any previous computational dynamo presented over the last 25 years. The potential rewards of such a correct theory and implementation will be great. We will understand how self-sustained dynamos equilibrate in this never-explored regime, and discover strengths and geometries of generated magnetic fields as a function of forcing. We will discover how to find reversing dynamos, just like on Earth, and understand the mechanisms at play. We will understand the energy requirements, ultimately understand core cooling and also be able to make more accurate predictions of future field evolution. We also aim to understand the new data returning from missions to the giant planets.
Drug Development for Eradication with InclusionComplex of Multifunctional-modifiedβCD

We studied the properties of an inclusion complex of amoxicillin (AMPC) in a multifunctional-modified β-cyclodextrin (mf-βCD) having an affinity for bacteria. The mf-βCDs used were βCDs modified by the introduction, on the end of a hydrocarbon chain linker, of a saccharide or urea substituent group expected to have affinity for bacteria. Using quantum chemical methods, we showed that the use of mf-βCD stabilizes AMPC against acid, and that formation of an inclusion complex should produce bacterial affinity and improve bactericidal efficiency. The chemical stabilization of AMPC by mf-βCD was tested by hydrolysis. We also showed that in order to form a 1:1 complex of AMPC and mf-βCD (AMPC-mf-βCD) functioning as a drug delivery system (DDS), the optimal conditions require mixing mf-βCD with AMPC at a molar ratio between 1:5 and 1:10 (AMPC:mf-βCD). We used Gaussian program to determine the precedence of inclusion of AMPC by mf-βCDs and to obtain optimized structures of the complex. We demonstrated the importance of orbital interactions and electronic correlations during complexation for the emergence of chemotaxis in Helicobacter pylori1) toward the urea substituent on mf-βCDs. We further used the self-consistent reaction field (SCRF) method to study the effects of solvent. Using the optimized structures under solvent-free conditions, we calculated the energies of each AMPC-mf-βCD complex in water by the SCRF method using B3LYP/6-31G* levels.