SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Nanostructured dielectric platforms for electric and magnetic field-enhanced spectroscopies and nonlinear photonics with low-loss characteristics

It is widely known that metals, such as gold and silver, when suitably structured at the nanometre scale, are able to focus light into very small (sub-wavelength) volumes, greatly enhancing its local intensity. For this unique capability such metallic nanostructures are often referred to as “nanoantennas”. In the last decade, metallic nanoantennas have opened up a wide range of applications in numerous fields, spanning (bio)imaging and sensing to the development of optoelectronic hybrid devices. However, since the mechanism of light confinement relies on the collective oscillation of free electrons, generation of heat via Joule dissipation is inherent to the process and detrimental effects arise for several uses, such as surface-enhanced spectroscopies and nonlinear optics.
The central objective of this project is to circumvent this issue through the use of dielectric nanoantennas made of silicon or germanium, which have been proposed recently as low-loss alternatives with relatively high field enhancement capability. Specifically, this research will determine, for the first time, the ability of the dielectric nanoantenna to selectively enhance a molecule’s electric and magnetic dipole emmisions, without perturbing the sample by undesired heating. Furthermore, this project will investigate the coupling of dielectric resonators to suitable nanomaterials for high-efficiency infrared-to-visible light conversion, and will design hybrid arrangements of dielectric and metallic nanostructures to combine the best of both worlds. Finally, dielectric metamaterials will be studied for both enhanced spectroscopies and nonlinear photonics to further improve these characteristics. The results of this work will have significant impact in a number of fields and will represent, for the case of silicon, the perfect scenario for the integration of optical nanoantennas and metamaterials with the extensively used silicon-based optoelectronics technology.
Seismic assessment of Japanese traditional wooden structure by dynamic interaction numerical analysis of surrounding ground

We conducted seismic evaluations of a traditional wooden building using three-dimensional earthquake response analyses. The building is registered as one of the Historic Monuments of Ancient Kyoto, UNESCO World Heritage Site, and is located in a region of strong earthquake motion from a scenario earthquake. The structure is an invaluable asset, but it is at risk of damage resulting from earthquake. Our numerical estimation was based on a dynamic interaction analysis between the building and the surrounding ground because it was located on the slope of a hill with complicated geophysical features. We also conducted a dynamic non-interaction analysis of the structure for a comparison with the aforementioned interaction model. Boring explorations and geotechnical tests were conducted before the assessment in order to investigate the ground foundation. We included the surrounding ground for a more realistic analysis because the seismic estimation for a model consisting only of the main structure differs significantly from that of the structure-ground coupling model. The results showed that the main wooden building was at risk of partial damage as it exceeded the safety limits prescribed for a scenario earthquake, and would collapse in the case of double the amplitude of the scenario earthquake. Language: en
CASEIFICIO SOCIALE SANTA MARIA: PROGETTO INNOVATIVO PER IL CONSOLIDAMENTO E L'AUMENTO DELLA SICUREZZA E DELLA PRODUTTIVITA AZIENDALE.

IL CASEIFICIO SOCIALE SANTA MARIA, FORTE DEL RICONOSCIMENTO CONFERITOGLI DAL CONSORZIO DEL PARMIGIANO REGGIANO, VUOLE ATTUARE UN IMPORTANTE INTERVENTO DI RISTRUTTURAZIONE E AMMODERNAMENTO TECNOLOGICO.-ATTRAVERSO OPERE MURARIE SI ANDRA AD AMPLIARE LO STABILIMENTO NEL QUALE VERRANNO INSERITE NUOVE ATTREZZATURE INNOVATIVE. -LA MOVIMENTAZIONE DELLE FORME, ATTUALMENTE, VIENE EFFETTUATA MANUALMENTE, COMPORTANDO SCARSA SICUREZZA PER GLI OPERATORI, BASSA VELOCITA DI MOVIMENTAZIONE E SCARSA SICUREZZA SULLA GESTIONE INTERNA DEL PRODOTTO.-ATTRAVERSO IL PROGETTO CHE SI VUOLE IMPLEMENTARE VERRANNO INSTALLATE NUOVE VASCHE DI SALATURA, OPPORTUNAMENTE SUPPORTATE DA IMPIANTI DI RICIRCOLO E VERRA POSIZIONATA UNA NUOVA VASCA PER LA PREPARAZIONE DELLA SALAMOIA, COMPRENSIVA DI FILTRI NECESSARI PER L'ELIMINAZIONE DELLE IMPURITA.-LE OPERE MURARIE SERVIRANNO, OLTRETUTTO, PER GARANTIRE L'INSERIMENTO ALL'INTERNO DEL CASEIFICIO DI UNA GRU A PONTE E DI CARRELLI PER LA MOVIMENTAZIONE AUTOMATICA DEL PARMIGIANO REGG
PROMOTION OF PORT COMMUNITY SYSTEM IN MEDITERRANEAN TRAFFIC

The project consists in: (1º) Achieving an effective implementation of the PORT COMMUNITY SYSTEM) (PCS) in 4 Mediterranean ports. (2º) Development of a platform allowing an effective communication of such systems. (3º) Assure an efficient utilisation of PCS and its services for all the potential users. The first step will consist of acquiring a deep understanding of all the works and experiences carried out in other environments, so as to derive maximum benefits, as well as of the legislation and official protocols, both European and international. The project does not intend to develop new protocols, nor harmonisation studies, but it intends to start from the work already accomplished. Likewise, each port shall study its management systems, particularly the penetration levels of the new communication technologies, so as to assess the effort needed for a PCS to be established. In parallel with the above, the management systems of the logistic operators linked to the ports in the project shall be studied in each territory in order to assess their capacity to take advantage of the subsequent establishment of the PCS. On the basis of the information gathered, the minimum requirements to be complied by all the PCS established, as well as the future system of communication among PCS, shall be defined. According to them, each port shall submit a plan for implementing its own PCS (different in scope for each port), and the development of the communication system among PCS will be commenced. As the same time as the defined solutions are being developed and established, an intense awareness-raising and communication work with logistic operators linked to the stakeholders will be developed, aiming at encouraging them to achieve a greater technological penetration in their management, so as to take better advantage of the subsequent establishment of the PCS. Special attention will be paid to three aspects: current services provided by the ports (singles Windows SW), software currently available for logistic operators, and new services and opportunities liked to PCS. Once the different PCS have been developed, a pilot test will be carried out, within a real environment and in each of the ports participating in the project. In order to assure the success of the pilot test and the subsequent continuity of the project, a wide training programme addressed to users and administrators will be implemented. About 2 months after the beginning of the pilot tests in ports, another pilot test will be carried out in order to verify the efficient functioning of the communication system among PCS. Once the pilot tests have finished and have been assessed, all the systems established will continue to operate normally, since they will be fully integrated within the management systems of the ports. Likewise, since the training materials were developed in such a way that they assure an autonomous training, new users will be able to join without specific training.
Ultrasonic preparation of cellulose/Ag/polyaniline conductive composites and its electrical properties

Cellulose/Ag/polyaniline conductive composites with excellent electrical conductivity were fabricated by the ultrasonic method for the first time. The products were characterized by UV–Vis spectrometer, Fourier-transform infrared spectroscopy, Scanning electron microscopy, Thermogravimetric and Conductivity analysis, and the results showed that the Ag nanoparticles (nanoAg) with the good conductivity coated uniformly on the surface of cellulose and improved the conductivity of cellulose/Ag/polyaniline composites significantly. The conductivity value was up to 0.348 S/cm, which was higher than pure polyaniline (0.142 S/cm) and cellulose/polyaniline composites (3.0 × 10−2 S/cm). In addition, compared with cellulose/polyaniline composites, cellulose/Ag/polyaniline composites also have the enhanced thermostability. The cellulose/Ag/polyaniline conductive composites would have a promising application in a variety of fields due to its unique structure and excellent properties.
The NYU ultracomputer---designing a MIMD, shared-memory parallel machine

The design for the NYU ultracomputer, a shared-memory MIMD parallel machine composed of thousands of autonomous processing elements is presented. This machine uses an enhanced message switching network with the geometry of an omega-network to approximate the ideal behaviour of Schwartz's paracomputer model of computation and to implement efficiently the important fetch-and-add synchronisation primitive. The hardware which would be required to build a 4096 processor system using 1990s technology is outlined. System software issues are discussed and analytic studies of the network performance are presented. A sample of efforts to implement and simulate parallel variants of important scientific programs is included. 37 references.
Humics—Their History in the Radiocarbon Intercomparison Studies

ABSTRACT Over the past 30 years, the format of the radiocarbon ( 14 C) intercomparison studies has changed, however, the selection of sample types used in these studies has remained constant—namely, natural and routinely dated materials that could subsequently be used as in-house reference materials. One such material is peat which has been used 12 times, starting with the ICS in 1988. Peat from Iceland (TIRI), Ellanmore (TIRI), Letham Moss (ICS, VIRI, and SIRI), and St Bees, UK (FIRI and VIRI) have been used, as well as a near-background peat from Siberia. In the main, these peat samples have been provided as the humic acid fraction, with the main advantage being that the humic acid is extracted in solution and then precipitated (the solution phase providing the homogenisation) which is a key requirement for a reference material. In this paper, we will revisit the peat results and explore their findings. In addition, for the last 8 years, the Letham Moss sample has been used in the SUERC 14 C laboratory as an in-house standard or reference material. This has resulted in several thousand measurements. Such a rich data set is explored to illustrate the benefits arising from the intercomparison program.
Mixed-effects modeling for concentration effect profiling in cardiomyocyte contractility assays

Background. With the advent of new realtime technologies such as impedance assays, extracellular field potential measurement and optical sensing for in vitro cardiac safety screening studies, researchers have now to frequently deal with analyzing voluminous amounts of complex time responses. In this context, main issues are to speed up the data analysis process and to extract accurate information for cardiotoxicity profiling. 
Objectives. A first objective is the development of an innovative computational method able to globally process a large set of in vitro cardiac signals (provided by 96, 384 and 1536-well microplates) instead of analyzing them once at a time. Such a statistical population approach has the advantage the account for the common characteristics between the individual responses. A second objective is to handle qualitative factors (type of cardiomyocytes, compounds and media, etc.) in the computational process. 
Methods. The proposed estimation method relies on the combination of a dynamic system identification method and a mixed-effect modeling technique. An output-error polynomial model structure is used for the system identification step and a stochastic approximation expectation maximization is implemented for the estimation of the hyperparameters. Input signals to be analyzed are the contractility amplitudes of cardiomyocytes submitted to compounds to be tested. Impedance signals and contractility amplitude were provided by a CardioExcyte96 system (Nanion Technologies). human iPSC-derived cardiomyocytes were provided by Cellartis Takara with 30,000 cells per well. 
Results. Our data-driven profiling method extracted four parameters that completely fit the contractility time variations and fully characterize the effect of compound concentration on the contractility amplitude. The proposed method not only estimates the values of the model parameters but also their uncertainty distribution. The latter allows to compute p-values associated with each effect.
Conclusion. We show that the population-based estimation method developed in this study is suited to the fully characterize dynamic effects in cardiomyocyte contractility assays. Each parameter becomes a profiling characteristics of the concentration effect. It can be applied to estimate concentration and compounds effects with an optimal accuracy and could be extended directly to multielectrode array and optical sensing responses.
Devices and systems for barcoding individual wells and vessels

The invention generally relates to devices and systems for individually barcoding sample vessels. In certain embodiments, the devices comprise an attachment member and an extension member, where the extension member can accommodate an identifier, such as a barcode. When loaded into a substrate, the barcoded vials are scanned by a barcode reader.
Pravastatin attenuates testicular damage induced by doxorubicin – a stereological and histopatological study

Abstract Background The aim of this study is to investigate the effects of pravastatin (PS) against doxorubicin (DOX)-induced testicular toxicity. Methods A total of 24 healthy male Sprague-Dawley rats were equally divided into four groups. Group I received normal saline, Group II received PS (20 mg/kg b.w.) by gavage, Group III was treated with DOX alone (15 mg/kg b.w., i.p.) and Group IV received the combination of DOX and PS. Results After 8 weeks, the results displayed that DOX caused a decrease in testicular volume and index, epididymal sperm count, seminiferous tubule diameter and germinal epithelium. DOX also reduced the number of spermatogonia, spermatoctyes and Sertoli cells as well as increased the lumen diameter of seminiferous tubules (p&lt;0.05) and the incidence of histopathological changes of the testis. Moreover, elevated malondialdehyde (MDA) levels and declined glutathione peroxidase (GPx) and superoxide dismutase (SOD) activities were observed (p&lt;0.05). On the contrary, PS treatment significantly ameliorated nearly all of these abnormalities (p&lt;0.05). Conclusions PS protects against DOX-induced testicular toxicity in rats, which is likely via the inhibition of oxidative stress and the increase of antioxidant enzyme activity.
Designing a new glue for the furniture industry together with an innovative application system.

SA 42799(2015/X) The planned design project will consist of designing a new line of adhesives for furniture. The new adhesive formula will be developed by the Applicant’s R & D team, and as part of external services, a system of innovative applicators and a visual communication system will be designed. The design process will consist of the following phases: 1) Diagnosis – the pre-submission phase, preceded by an initial audit of the company in terms of the company’s previous activities and its technical, human and financial resources, as well as an analysis of the market environment. The result of the Diagnosis confirms that CX80 has a great potential to implement a design project in terms of designing a new line of adhesives and dedicated applicators. 2) Synthesis and analysis – defining the strategy for further actions necessary to develop a new design project, including the preparation of the assumptions for the project brief and the definition of project directions. Design Brief will set out design assumptions and guidelines for the new product and its packaging. 3) Develop designs and prototypes of the new product and carry out the necessary tests, including designing a spray head packed in aerosol cans, a system of interchangeable tool tips for precise application – brushes and brushes, needles, tubes, mouthpieces, spatula, etc., and an applicator for small packaging. 4) Consulting services related to the implementation of the new product – development of a visual communication system for the new product line together with the preparation of the brand manual, promotional and information materials, promoting the developed innovative solutions. After completion of the design process, in order to implement a new line of adhesives, an initial investment in fixed assets such as a set of moulds for the production of innovative applicators developed in Phase 3 will be realised.
The Learning Curve by Varied Operative Procedures in Laparoscopic Colorectal Surgery

Purpose: This study aimed at evaluation of the learning curve for laparoscopic colorectal surgery with varied operative procedures. Methods: From June 2004 to May 2010, 269 consecutive patients underwent laparoscopic colorectal surgery. Patients were divided into four groups according to operative methods: right-side colectomy, left-side colectomy, rectal resection, and total colectomy group. Each group was divided into threeearly, middle, and late-groups according to operation numbers. Learning curves were generated for each group using moving average methods. Prospective collection and retrospective review of data on operative outcomes, including open conversion, operation time, intra-operative blood loss, postoperative hospital stay, and postoperative complication were performed. Results: Operations included 75 right-side colectomies, 12 left-side colectomies, 178 rectal resections, four total colectomies, and seven open conversions (2.6%). The mean operative time for right-side colectomy and rectal resection showed a significant decline from the early group to the middle and late groups, while the left-side colectomy group showed no significant difference. Operation time was platitude after 50 cases of whole laparoscopic colorectal surgery, 11 cases in the right-side colectomy group, eight cases in the left-side colectomy group, and 34 cases in the recto-sigmoid resection group. Conclusion: For the surgeon, laparoscopic colorectal surgery can be performed more independently after 50 cases. The learning curve may be determined according to the general skill of laparoscopic colorectal surgery. The question of whether the learning curve is determined by varied operative procedures has not yet been resolved.
Anonymity guarantees of the UMTS/LTE authentication and connection protocol

The UMTS/LTE protocol for mobile phone networks has been designed to offer a limited form of anonymity for mobile phone users. In this paper, we quantify precisely what this limited form of anonymity actually provides via a formal security model. The model considers an execution where the home and roaming network providers are considered as one entity. We consider two forms of anonymity, one where the mobile stations under attack are statically selected before the execution, and a second where the adversary selects these stations adaptively. We prove that the UMTS/LTE protocol meets both of these security definitions. Our analysis requires new assumptions on the underlying keyed functions for UMTS, namely that a set of pseudorandom functions are agile. This assumption, while probably true, has not previously been brought to the fore.
A study of surface condensation defect improvement after cryogenic implantation

For USJ engineering, cryogenic implantation is proposed for the reduction of dopant TED effect (i.e., Xj reduction) and the reduction of EOR defect formation. (i.e., less dopant deactivation)1 However, condensation defects are formed during the wafer warm up period due to the temperature of the cold wafer surface, and this impacts the device electrical performance. In this study, we use a heater lamp and post N 2 purge function to improve the lower wafer temperature issue after the cryogenic implantation process. In order to minimize the wafer to wafer temperature difference, we can adjust the wafer cassette elevator position and post N 2 purge time. Turn-on heater lamp 8min with elevator position at slot14 and post N 2 purge 40min, we can improve the wafer surface temperature to ∼23°C with wafer to wafer temperature range ∼0.6°C. The wafer surface temperature after the heater lamp function is close to room temperature implantation and it would be benefit to suppress the surface condensation defects formation.
Proof of concept and pre-commercialisation of personalised liquid biopsies in cancer therapy

Extremely high sensitivity is needed for the detection of cancer biomarkers during the follow-up of the treatment or post-operation period.  We have identified a novel technology that enables very sensitive detection of single-nucleotide polymorphism from blood, enabling point-of-care screening of liquid biopsies. Our diagnostics platform will consist of new chemistry and device, and is an open system for designing new diagnostic targets. This will enable customized follow-up of the cancer medication in local hospitals and health care centers. The technology is based on our invention (US patent allowed) further developed in the ERC CoG project, but will have features for automated sample preparation and lab-on-chip design, which need to be verified and combined in the complete platform.  For pre-commercialization of the technology, the sensitivity and accuracy of the chemistry will be determined and compared against competing mass spectrometric platform (UltraSEEK by Agena), upgrading our technology from phase TRL 4 to TRL 5. Patent shield of the technology is extended and options for transferring IPR from the University are clarified. Results are presented in investor convention and oncology conferences, and negotiations with investors and out-licensors are started. Three international biotech companies take part in the steering group. The technology allows business potential in device and kit production, but especially in international service business for personalised panel components and medical consultation. The expected price of the device and sample prep will be 30-40% cheaper than that of the closest competitor, but even better it allows flexible design of personalized diagnostic panels. The development for boosting the innovation to market will continue either through a spin-out supported by international investors, together with partnering companies, or through out-licensing.