SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
[Spatial distribution of inhalable particulate and association with respiratory disease in Beijing City].

Inhalable particulate has become the premier pollutant of Beijing, which has enormous influence on the environmental quality of the city and health of the residents. Inhalable particle pollutants (particulate matter of 0.3, 0.5, 3.0 and 5.0 microm) during the heating period and the non-heating period in 2008 and 2009 were collected, and spatial analysis was used to study the spatial distribution of each pollutant. Meanwhile, the hospital data about respiratory disease during the same time was gathered and counted. Then the relativity between inhalable particulate pollutants and respiratory disease was studied by grey correlation analysis on the base of regression analysis. The results showed that spatial distribution of fine particle was diverse but the pattern of coarse particle was similar. There was certain association between respiratory disease and inhalable particle pollutants. Heating period was the highest incidence period of respiratory disease. The prevalence of respiratory disease was higher in heating period than non-heating period. The concentration of fine particle was higher than that of coarse particle both in heating and non-heating periods, and fine particle had more effects on the respiratory system disease than coarse particle.
The Effect of Implant Failure After Symphyseal Plating on Functional Outcome and General Health

To relate the incidence of implant failure after internal anterior fixation of the pelvic ring to functional outcome and the health-related quality of life in patients.Retrospective chart and radiographic review.Level I Trauma center.We retrospectively identified all patients who were treated with symphyseal plating for traumatic symphyseal diastasis between January 2003 and December 2013. Patients were asked to complete 2 questionnaires, the SF-36 and the Majeed score. A retrospective chart and radiographic control review were performed on all patients. The following data were collected: demographic data and details regarding the pelvic surgery. Computed tomograms were used to determine fracture classification and quality of reduction. Conventional radiographic follow-up were used to detect implant failure.A total of 37 patients enrolled the study. Implant failure occurred in 11 (30%) patients resulting in the identification of 2 groups, "implant failure" (n = 11) and "intact implants" (n = 26). The baseline characteristics were equal in both groups. The analysis of the questionnaires revealed that the SF-36 score was not significantly different in any of the dimensions between the both groups. Patients in the implant failure group scored higher on all of the Majeed items, including the total Majeed score, but the difference did not reach statistical significance of P < 0.05.Our study showed comparable results regarding the general health measured by the SF-36 for both groups and higher Majeed scores for patients with implant failure compared with patients with intact implants.Therapeutic Level III. See Instructions for Authors for a complete description of levels of evidence.
Novel strategies for anti-hiv-1 therapy: small molecules targeting rna partners of the nucleocapsid protein

European Commission considers HIV/AIDS as a top priority and significantly invests in research devoted to the development of alternative therapeutic strategies leading to new antiretrovirals, which are urgently needed to overcome the emergence of resistance to existing drugs. 

The “BICEPSvsHIV” project proposes a novel and innovative strategy that draws the spotlight on RNA. Specific RNA sequences of the viral genome are substrates of the HIV-1 nucleocapsid (NC), a highly conserved protein known for promoting remodeling of nucleic acid structures in essential steps of the virus replication cycle. The proposed strategy consists in the employment of bis-3-chloropiperidines (BICEPS) as RNA cross-linking agents able to freeze selectively the tridimensional conformations of the RNA partners of NC, thus impairing its activities.

RNA is a challenging molecule from the medicinal chemistry perspective, but the rewards it can yield are invaluable. The Experienced Researcher (ER) will work at The RNA Institute (SUNY Albany) during the outgoing phase, aimed at 1) the elucidation of BICEPS detailed molecular mechanism of reaction towards RNA and 2) the identification of BICEPS targeting selectively the RNA substrates of NC. During the incoming phase at the University of Padova (UNIPD), the achievements will be translated into 3) the thorough biological evaluation of the in vitro NC inhibition by BICEPS, leading to 4) the identification of anti-NC lead compounds.

The project provides the ER with an outstanding training-through-research opportunity by means of a personalized multidisciplinary project, in which the ER will enlarge her scientific profile with new excellent skills. The training includes both scientific and transferable skills, aimed at the reinforcement of the ER professional maturity and independence and at the establishment of long-term international collaborations.
A review on the applications of image logs in structural analysis and sedimentary characterization

Abstract Image logs provide important information on lithology, sedimentary textures, paleoflow directions, fractures and in situ stress analysis. Lacking of criteria used for establishing the image log facies limits the applications of image logs in sedimentary reservoir interpretation. This paper provides a thoroughgoing review focusing on the recent applications of borehole image logs for sedimentological and structural description and interpretation, and aims to establish image log facies which can provide guidelines in sedimentary reservoir interpretation. This paper firstly summarizes the principles and basic characteristics of various imaging logging tools, and then briefly introduces the pre-processing workflow of the image log data. Then the generated images are used for depth and orientation shifts of cores by calibrating individual sedimentary and structural features. Descriptive and concise image log facies are established based on combinations of image textures including dip type, dip pattern, and color scheme, and the characteristics as well as physical criteria for each individual image facies are summarized. The established image log facies are then interpreted in terms of structural and sedimentological features such as lithology, sedimentary structures, vugs, fractures and faults. The image log facies and its stacking patterns are then used to interpret the lithofacies associations by calibrating with cores and conventional logs. Natural fractures and induced fractures are recognized by image logs, and the principles of breakouts and drilling-induced fractures for in-situ stress analysis are reviewed. Then the applications of image logs in investigation of fracture attitudes and states, as well as in computation of fracture parameters are summarized. The procedures to evaluate fracture effectiveness through image logs are discussed. At last, the application of image logs for structural dip analysis is reviewed, and image logs are used for recognizing faults, fracture sets, and attitudes of stratum through the dip patterns. The basic procedures for paleocurrent reconstruction, which includes dip picking of cross beddings, structural dip determination and structural dip removal, are reviewed. Then the paleocurrent directions of the Lower Cretaceous Bashijiqike Formation in the Kuqa depression were reconstructed, which could help further understanding of the depositional systems. This review will help extend the utility of image logs in interpreting small to large -scale sedimentary and structural features, and bridges the gaps between well log analysis and sedimentary and structural interpretation.
Unternehmen *individuell*

DAS PROJEKT „KULTURUNTERNEHMEN 2.0“ ZIELT DARAUF AB, UNSER UNTERNEHMEN IN DREI HAUPTASPEKTEN WACHSEN ZU LASSEN: KÜNSTLERISCH-TECHNISCHE PRODUKTION; ORGANISATION UND VERWALTUNG DER TÄTIGKEITEN; NEUE WEGE DES UMGANGS MIT NUTZERN/ÖFFENTLICHEN.
The use of outcome measures relating to the knee

Abstract Accurate outcomes assessment is one of the fundamental aspects of any reliable research. There are a vast number of outcome instruments currently available in orthopaedics. This plethora and diversity can lead to frustration when it comes to choosing the appropriate option. In this article we address the essential properties an outcome measure must possess, aiming to allow an informed selection of the most suitable instrument. We describe and illustrate key psychometric properties that are to be assessed when judging suitability of an instrument, such as validity, reliability and responsiveness. We also review some of the most commonly used and recommended outcome measures available in regard to different knee pathologies. With no intention of recommending a specific option, we briefly outline advances and shortcomings of named instruments.
Uncover and promote tolerance to temperature and water stress in camelina sativa

European agriculture is increasingly challenged by climatic variability and weather extremes causing drought and temperature stress to crops that are very often highly sensitive to abiotic stress conditions, resulting in low productivity and yield loss. Camelina sativa is a reemerging native European oilseed that has retained its natural stress tolerance and receives attention because of its untapped breeding potential, adaptability, yield stability and high performance in variable environments. UNTWIST will unravel the stress response mechanisms of the climate-resilient crop Camelina and reveal its successful stress adaptation strategies for implementing them in new agronomic solutions. UNTWIST brings together a unique consortium with complementary expertise in stress mechanisms, (epi)genetic regulation, physiology, metabolism, crop modelling, and crop management to drive biological discovery. Stakeholder expertise by three SMEs will allow smooth knowledge transfer into crop improvement and new management strategies. UNTWIST will use genetically diverse Camelina cultivars in open field and stress-controlled experiments together with sophisticated systems-based approaches to uncover the plant’s adaptive multi-layered stress response mechanisms. Complex data integration will provide genome scale models revealing plant strategies for managing uncertainty and a validated accurate model to predict crop performance in variable environments. Moreover, UNTWIST will deliver new tools and markers for effective translation into other crops. Finally, UNTWIST will meet the climate challenge in agriculture by providing elite-adapted Camelina germplasm and developing agronomic management practices for ready adoption by farmers into new climate resistant cropping systems.
Direct pathway cloning of neglected bacteria in the hunt for novel (bio-)chemistry

To overcome recent global health threats, such as antibiotic resistance, a resurgence in the discovery of new chemical and thus biomedical diversity from microbial sources is needed. Genome mining in combination with heterologous expression is an approach that will overcome these challenges. It involves incorporation of yet uncharacterized natural product genetic loci into a fast growing heterologous host. For this approach, a prolific source of novel natural product gene clusters is vital. Our collaboration with the Zentralinstitut für Ernährungs- und Lebensmittelforschung (ZIEL, Technische Universität München) provides direct access to bacterial isolates completely unexplored in regards to their potential for natural product biosynthesis. Our genome analyses have revealed that many of the ZIEL isolates harbor a large number of uncharacterized natural product gene clusters. Thus, the aim of this proposal is to heterologously express natural product gene clusters from these neglected bacteria to discover novel natural product (bio-)chemistry. Because these organisms are poorly studied, the likelihood of discovering rare or novel biochemistry is immensely increased. Here, we will utilise a novel combination of synthetic biology techniques referred to as Direct Pathway Cloning. This will enable expression vectors to be constructed by large-amplicon PCR (up to 20kb) coupled to Gibson assembly. Development of the methodology is set to revolutionise synthetic biology and metabolic engineering. Downstream outcomes of this proposal will be the identification of novel, potentially bioactive natural products, the characterisation of unusual biochemistry and the addition of enzymes to the ‘biocatalytic toolkit’ for natural product synthesis and structural alteration.
Dosikit, a first portable field medical device for fast triage of people after external irradiation

Acubens was founded in 2014, to develop and commercialize new game-changer medical diagnostic devices around NRBC emergency. Our team gathers young and experimented doctors, and seasoned business managers, uniting their competencies to develop nuclear/radiological/biological innovative transportable biodosimetry devices. Nuclear/radiological accident can expose individuals to radiation, with the need for fast triage of potentially exposed people requiring immediate medical care. There is today a lack of irradiation biodosimetry tools that can be used in the field, by non-specialist staff, giving immediate results and exposure cartography in case of Partial-Body irradiation (PBI).
To fulfil this critical unmet need for better initial crisis management, we invented the DosiKit device and fast test (45 minutes) to identify and classify irradiated individuals, directly in the field. This development was initiated in 2009 by the French Atomic Energy Commission within the European Commission program, BOOSTER (‘BiO-dOSimetric Tools for triagE to Responders’), and then continued by Acubens.
DosiKit technology is protected by 3 international patents and has reached TRL6 with a prototype validated in a large-scale exercise performed with the French army. Several collaborations are undergoing for biological validation with French research institute and hospitals.
Scientific and technical development was published in 3 scientific publications and many international oral communications. A strong contact has established with French, Germany, Israel, US and Singapore armies (LoI).
This DosiKit product will be on the market in 2022, starting in Europe and then extending worldwide. Forecasted sales revenue is 15 M€ in 2024.
The objectives of this phase 1 SME-Instrument are: (1) the final Biological and Technological validation of the device, (2) IP, FTO, Regulatory and risk assessment studies and (3) a market survey in Europe and USA to schedule our commercial actions.
FAN ASSEMBLING STRUCTURE AND FAN DEVICE HAVING THE SAME

The disclosure provides a fan assembling structure and a fan device having the same. The fan comprises a frame having an upper board, a lower board and a circular connector, and blades disposed in the frame. The lower board comprises four side edges in sequential connection. A first fixing hole is at the first side edge, and a second fixing hole is at the upper board. The structure comprises an assembling board having a bottom plate and two parallel side plates. The bottom plate comprises a ventilating area. A through hole is defined at a first side of the ventilating area, and a hook is disposed on a second side of the ventilating area. And at least one protrusion extends inwardly from an inner side of at least one of the two parallel side plates, a guiding slot being formed between the protrusion and the bottom plate.
Contribution of integrated geophysical data in the structural characterization of the El Hamma graben zone (Southern Tunisia): Example of a pull-apart basin along the South Atlasic Fault Corridor

Abstract The El Hamma-Gabes Region in southeastern Tunisia belongs to the crustal shear zone of the South Atlasic Fault Corridor, which corresponds to the Meso-Cenozoic North African margin. So far, most geological works on this region are on the stratigraphic order. However, there are few tectonic and structural studies carried on the style and mechanism of structural deformation. The present work analyzes the subsurface structure of the El Hamma grabens area based on gravity and seismic data , calibrated by stratigraphic and tectonic elements. The El Hamma-Gabes Zone is characterized by a horst and graben system associated with N130˚-150° trending parallel extensive/transtensive faults. Two main grabens are recognized: the El Hamma graben in the west and the Chenchou graben in the east. They are separated by the Jebel Hallouga horst. These structures relate to two N100˚-120° trending principal shear corridors (PSC) arranged in right echelon, being the Oum Ali-Fejej Shear corridor towards the northwest and the Matmata-Medenine Shear corridor towards the southeast. Stratigraphic and structural data collected from several outcrops were correlated with the tectonic events and paleostress reconstruction. New data shows that the PSCs marked a dextral transtensive kinematic framework during the N80° directed Upper Cretaceous extension. The extensional movements are the N150˚-180° Paleogene extension and associated transpression during the N130° Neogene shortening. The dextral sliding generated and maintained the opening of the El Hamma-Gabes graben system, creating a “pull-apart” basin that opened in an extensive ramp between the two PSCs. The overall extension of this ramp is estimated to 15% of the initial width.
Laparoscopic versus open splenectomy and esophagogastric devascularization for portal hypertension: a Meta-analysis

Objective: To evaluate the efficacy and safety of laparoscopic and open splenectomy and esophagogastric devascularization for portal hypertension by means of systematic review.Methods: The literature of studies related to laparoscopic versus open splenectomy and esophagogastric devascularization was collected by searching the national and international online databases.he articles were screened according to the inclusion and exclusion criteria.Ater data extraction and quality assessment,Meta-analysis was performed by using RevMan 5.2 sotware.Results: No randomized controlled trial was found in the literature,and 11 non-randomized controlled clinical trials were inally included,with a total of 494 patients,of whom,227 cases underwent laparoscopic surgery(laparoscopic group) and 267 cases were subjected to open surgery(laparotomy group).Compared with laparotomy group,the results of Meta–analysis showed that in laparotomy group,the operative time was prolonged,and the intraoperative blood loss,surgical complications and length of postoperative hospital stay was reduced,but the hospitalization costs were increased.All the diferences reached statistical signiicance(all P0.05).Conclusion: Compared with open surgery,laparoscopic splenectomy and esophagogastric devascularization has the advantages of reduced intraoperative blood loss,postoperative hospital stay and complications,but it has increased hospitalization costs and operative time.However,this conclusion should be considered cautiously,due to limitations in the quality and quantity of the included studies.
Time line inference from story sentence with time series

Recently, we can find many literary works on the Web. Automatic summarization is effective method to find favorite work through various works. But, stories have no logical structure like minutes or news papers. So, many exiting researches of automatic summarization are not effective for stories because these target minutes or news papers only. System optimized for stories is necessary. We focused on time series at story, a type of structure of story. We organized the system to infer it. System infers four types of time series by using timeword database. We tested features of four time series. System was checked it worked at story sentences.
A Study on the Efficiency Change of the Infrastructure Investment in Liaoning Coastal Economic Belt Based on Malmquist-DEA

These days, the strategy of Developing Liaoning Coastal Economic has become a state strategy, during which the infrastructure construction is playing an important role. Based on the Malmquist-DEA method, this paper calculates the efficiency change of infrastructure investment in 2000-2009, and evaluates the changing trend of these six cities. The following conclusions are drawn: Except Dalian, the efficiencies of infrastructure investment in the other five cities are decreasing, The main factor that has influence on the infrastructure investment efficiency in this region is technology development, The pure technology efficiency of infrastructure investment in Liaoning Coastal Economical Belt has showed a decreasing trend in 6 of the 10 years, which means that the capability of construction organization, operation management and policy formulation urgently needs to be improved.
Human rights – mutually raising excellence

The project “HURMUR: Human rights – mutually raising excellence” will decisively expand the world-class research area of human rights in Europe. Tallinn University Law School will develop research excellence of human rights and become involved in global research and regional dissemination networks through specific activities of an outstanding consortium, where two other partners are premier global academic institutions in the field of human rights – the Danish Institute for Human Rights and Walther Schücking Institute of International Law (Kiel University, Germany). Their rennomee which is a guarantee that Tallinn University Law School will develop capacity to i) become a leader in the Baltic region of participating in state-of-the art research of human and fundamental rights, ii) initiate new research and development project of European magnitude exploring the changing nature of human rights in the contemporary society; iii) build bridges between Estonian/Baltic/Russian human rights research and activist communities.
This goal is achievable via: i) organizational reform of Tallinn University’s International Research Centre of Fundamental Rights; ii) establishment and publication of a new regional peer-reviewed academic journal, the East European Yearbook on Human Rights; iii) strengthened research capacities of TLU on universality of human rights (including in particular freedom of speech, freedom of religion, and identity rights), and human rights narratives and discourses, and on new human rights (including rights related to well-being; rights related to the exercise of public authority; rights related to new technologies and rights related to identity and personality), as well as increased publication activity in this area; iv) increased dissemination and communication of TLU research and knowledge to the public, including academia, policy makers, law makers and civil society.