SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Cross-Layer resilience for rack-scale disaggregated memory

Data-intensive applications, such as search, social connectivity, and e-commerce, are increasingly relying on computer memory for storing and processing a large amount of data with low latency. Emerging disaggregated memory meets this growing demand by leveraging recent technology advances in high-density, byte-addressable non-volatile memory and low-latency interconnects to provide a large memory pool shared across micro-server compute nodes. With a larger memory density and capacity though, memory errors will become more frequent. Addressing such errors becomes paramount as they can cripple service availability and cause data loss. However, established hardware techniques for tolerating memory errors transparently to application software, originally developed for DRAM-based main-memory systems, become impractical at the scale of disaggregated memory due to increasing performance, energy and area overheads. This research will investigate and develop cross-layer memory resilience techniques where software and hardware work together cooperatively to prevent service unavailability and data loss due to memory errors in disaggregated memory with low overhead. It capitalizes on the existing strengths of the experienced researcher (ER) in the area of system software design for non-volatile memory and expertise of the host on memory fault tolerance and micro-server architectures. It will lead to several publications in top-quality venues and will inform forthcoming industrial efforts to develop resilient disaggregated memory micro-server architectures, thus contributing to the research output, visibility, and economy of Europe. Overall, the fellowship will give the ER the opportunity to reintegrate into a long-term academic position in Europe, after a long and fruitful research career in the academic and industrial sectors of the United States. The ER will emerge from the project with new skills and the capability to effectively lead his own research group.
Carica.: Trasferimento di energia elettrica mediante induzione in strutture in calcestruzzo

Il progetto Becharged, promosso da SECIL, propone lo sviluppo di strutture modulari in calcestruzzo con un sistema di ricarica induttiva per veicoli elettrici e un sistema di illuminazione/segnaleto completamente integrato con un elevato grado di innovazione.
Tourist Valorisation and Modern Pentathlon: the Seasons of Sport over Central Adriatic Region

The proposal aims to strengthen of the cross-border adriatic collaborations through the valorisation of the territory, the development and the strength of tourist and sport infrastructures of the Abruzzo Region. It will be important effects such as an integration effect between tourist services and a valorisation of less important or less popular tourist and sporting localities. The main objective of the project is to create a network of sporting and tourist centres that could add value to Abruzzo region and that could represent an exportable model in the Balkan partner nation. It will be possible to realize that kind of partnership through the spread of modern pentathlon.
METAL PANEL ELECTRICAL BONDING CLIP

A clip for electrically bonding a pair of adjacently-disposed metal panels is disclosed. One embodiment has such a clip (104) having a first clip member (112) and an oppositely disposed second clip member (116). The surface (114) of the first clip member (112) that faces the second clip member (116) includes at least one grounding projection (128), while the surface (118) of the second clip member (116) that faces the first clip member (112) also includes at least one grounding projection (128). The clip (104) may be installed on a standing seam (102) of a panel assembly (100), with its first clip member (112) engaging one of the metal panels 82" that define this stand seam (102) and with its second clip member (116) engaging the other of the metal panels 82" that define this same standing seam (102).
Fast Optimal Design of Micromagnetic Devices Using FastMag and Distributed Evolutionary Algorithm

A new software framework is presented for fast optimal designs of micromagnetic devices. The developed framework adopts a fast micromagnetic (FastMag) simulator as a micromagnetic solver, and utilizes distributed evolutionary algorithm in Python (DEAP). The framework makes use of a simple Linux utility for resource management (SLURM) in order to run and manage multiple micromagnetic simulations concurrently on a Linux cluster. Various design variables can be designated including material and geometry parameters. The whole design cycle is automated including the mesh generation, and the status of the evolution and multiple simulations can be monitored and managed easily. By combining high computing speed of FastMag and distributed optimization capability of DEAP and SLURM, the optimal designs of micromagnetic devices can be performed rapidly and efficiently. As numerical examples, the optimal designs of a spin-torque oscillator and a magnetic random access memory device are performed.
METHOD AND DEVICE FOR THE ADDITIVE MANUFACTURING OF COMPONENTS

The invention relates to the field of the additive manufacturing of components, which are formed by the direct deposition of a substance, in the form of granules of a metal or non-metal, which passes from a reservoir into a melt bath, produced by the thermal energy of a laser or electron beam, and subsequently crystallizes. The granules enter the melt bath without the intervention of a gas stream, the path and rate of travel of said granules changing while they are in flight under the effect of an electromagnetic field. The granules travel within a chamber, falling into the melt bath from above from a reservoir, from which they are fed at a set speed by the rotation of an adjustable screw feed, and passing through a system of electromagnetic devices, which control the path of the granules by means of electromagnetic fields. The coordinates of this path are tracked by sensors, which transmit a signal to a computer, wherein the flight path of the granules is adjusted by control via the electronic devices and the delivery speed and volume of the substance is adjusted by adjusting the rotation of the screw feed. The invention increases the efficiency of the production cycle, reduces the dimensions of the equipment and increases the accuracy and speed with which material is delivered for the manufacture of a component, while enabling adjustment of the amount, temperature, path and fraction of said material and increasing the strength of the component.
Asymmetric copper catalyzed multicomponent coupling

The development of operationally simple methods for the rapid and efficient, catalytic construction of high value products from simple starting materials is key to the future of synthetic science. Moreover, if high value chiral products can be assembled from several readily available achiral components in a one-pot process then diverse collections of important compounds can be quickly constructed by simple variation of the material inputs. Even more challenging, but attractive to the scientific community, would be a multicomponent process catalyzed by a low-cost metal using a commercially-available ligand to control the regiochemistry and relative and absolute stereochemistry of the cross-coupling process.

In this project we will develop one-pot processes involving imines that deliver important, functionalized amine products that are hard to make using the current state-of-the-art in synthesis. In particular, we will develop the enantioselective union of imines, allenes, and boron–X components, mediated by an inexpensive, readily available copper catalyst, which delivers versatile functionalized homoallylic amines that are privileged substructures in bioactive compounds and flexible building blocks for the construction of other biologically-significant motifs.

For example, the brand new methodology will be applied in the target synthesis of validated bioactive molecules and in the rapid generation of libraries for medicinal chemistry exploration. The action will also open new vistas for other enantioselective multicomponent couplings using this approach. This ambitious project will expose Dr. Manna to new areas of physical techniques as well as provide high level synthetic training, which in addition to transferable skills gained, will place him in a uniquely strong position to advance in his career.
Improving Protocols for Protein Mapping through Proper Comparison to Crystallography Data

Computational approaches to fragment-based drug design (FBDD) can complement experiments and facilitate the identification of potential hot spots along the protein surface. However, the evaluation of computational methods for mapping binding sites frequently focuses upon the ability to reproduce crystallographic coordinates to within a low RMSD threshold. This dependency on the deposited coordinate data overlooks the original electron density from the experiment, thus techniques may be developed based upon subjective-or even erroneous-atomic coordinates. This can become a significant drawback in applications to systems where the location of hot spots is unknown. On the basis of comparison to crystallographic density, we previously showed that mixed-solvent molecular dynamics (MixMD) accurately identifies the active site for HEWL, with acetonitrile as an organic solvent. Here, we concentrated on the influence of protic solvent on simulation and refined the optimal MixMD approach for extrapolation of the method to systems without established sites. Our results establish an accurate approach for comparing simulations to experiment. We have outlined the most efficient strategy for MixMD, based on simulation length and number of runs. The development outlined here makes MixMD a robust method which should prove useful across a broad range of target structures. Lastly, our results with MixMD match experimental data so well that consistency between simulations and density may be a useful way to aid the identification of probes vs waters during the refinement of future multiple solvent crystallographic structures.
Research on the Application of Target Cost Contract in Construction Projects

As competition is fierce in the construction market,the contact price of construction projects is close to the actual cost price.Compared to the traditional fixed unit price and fixed lump sum model,the Target Cost Contract(TCC) provides a new way for owners and contractors.Based on the introduction to the concept and characteristics of TCC,this paper illustrated the operation mechanism by the mathematic model and theoretical analysis.For the specialty of TCC,risks during the process of construction need be properly managed,especially the changes of scope and errors or omissions of the tender documents.At last,this paper discussed its advantages and disadvantages.Some suggestions were put forward to promote its implementation.
INTEGRATED MICROWAVE-TO-OPTICAL SINGLE-PHOTON TRANSDUCER WITH STRAIN-INDUCED ELECTRO-OPTIC MATERIAL

Transducers and methods of making the same include a substrate having a cavity with a diameter that supports whispering gallery modes at a frequency of an input signal. A focusing structure in the cavity focuses the electric field of the input signal. A resonator directly under the focusing structure has a crystalline structure that generates an electro-optic effect when exposed to electrical fields. An electric field of the input signal modulates an output signal in the resonator via the electro-optic effect.
Digital single cell immunology: decoding cellular interactions for improved immunotherapy

Successful immunotherapy against cancer is the result of a multitude of cellular interactions within the immune system. It is highly exciting how vaccination with small numbers of human plasmacytoid dendritic cells (pDCs) can induce anti-tumour immunity in metastatic cancer patients. Remarkably, how pDCs, as an extremely rare subset of cells, can act as Swiss army knives to regulate the tight balance between tolerance and immunity: i.e. secrete massive amounts of type I IFNs, prime T cells and exert cytotoxic effector functions, is still elusive. Do pDCs possess all functions or comprises the population distinct functional subsets all with their specialized roles. I will unravel which pDC is superior in inducing cytotoxic T cells (CTLs) for augmented cancer immunity. Despite advances in single cell technologies, understanding the role of heterogeneity in immune cell populations, remains poorly understood. In ImmunoCode, I will develop a novel and ambitious single cell technology platform, wherein innovative microfluidic approaches and single cell transcriptomics allow 1) functional analysis of single (pairs of) immune cells and 2) design of minimal environments under the omission of external factors that could influence cellular behaviour. This approach will provide me with the unique opportunity to unravel pDC function and plasticity. Although in this ERC proposal I will focus on understanding pDCs heterogeneity, my technology can in fact be exploited to any cell type that shows heterogeneous function. My unique and high-risk technical approach allows for decoding immune cell-cell or cell-pathogen interactions longitudinally and in great detail which will revolutionise the fields of immunology and cellular immunotherapy. Ultimately, ImmunoCode will have a tremendous impact by refining the design of vaccine strategies and the development of differently composed cellular vaccines to battle cancer and infectious and auto-immune diseases.
Solid catalysts for activation of aromatic c-h bonds

Objectives
The H-CCAT project designs, upscales and shapes hybrid catalysts for the C-H functionalization of aromatic compounds. These solid catalysts will possess better recoverability, higher turnover numbers and better selectivity than current homogeneous catalysts for these reactions. The solid catalysts are applied at demonstration scale in the step-economical production of arylated or alkenylated aromatics, yielding motifs of active pharmaceutical ingredients. 
Methodology
We will design heterogeneous hybrid catalysts featuring deactivation-resistant active sites, based on N-heterocyclic carbenes (NHCs) or diimine ligands and active metal ions. Via efficient, one-step protocols based on self-assembly, these sites will be embedded in robust porous hybrid materials like hybrid silica or metal-organic frameworks. Deactivation or metal aggregation will be prevented by site isolation or by efficient metal reoxidation (for the oxidative alkenylations). Metal leaching is precluded by using strong bonds between metals and embedded ligands like NHCs. Flow protocols will be designed to maximize the turnover numbers. Catalyst synthesis will be scaled up to kg scale, using efficient one-step protocols, minimizing use of solvents or waste formation. Soft shaping methods, e.g. spray drying, will preserve porosity and activity of the hybrid solids. A demonstration is conducted at minipilot scale at the J&J site (Belgium), allowing LCA analysis, techno-economic assessment and elaboration of the business plan.
Relevance to work program
The catalysts feature new, deactivation resistant active sites; their TOF/TON is maximized by an appropriate porous structure which even can be swelling. Catalysts are produced using innovative one-step protocols to form porous hybrid catalysts as powders or even immediately as shaped objects. The molecules targeted have strong biological and pharmaceutical relevance; they target diseases like influenza, cancer or HIV (case study: Rilpivirine).
Cross-Reacting Antibodies Enhance Dengue Virus Infection in Humans

Dengue virus co-circulates as four serotypes, and sequential infections with more than one serotype are common. One hypothesis for the increased severity seen in secondary infections is antibody-dependent enhancement (ADE) leading to increased replication in Fc receptor-bearing cells. In this study, we have generated a panel of human monoclonal antibodies to dengue virus. Antibodies to the structural precursor-membrane protein (prM) form a major component of the response. These antibodies are highly cross-reactive among the dengue virus serotypes and, even at high concentrations, do not neutralize infection but potently promote ADE. We propose that the partial cleavage of prM from the viral surface reduces the density of antigen available for viral neutralization, leaving dengue viruses susceptible to ADE by antibody to prM, a finding that has implications for future vaccine design.
Analisis Pemasaran Sayuran di Dusun Kerinjing Kelurahan Agung Lawangan Kecamatan Dempo Utara Kota Pagar Alam

The purpose of this study is (1) identifying and describing vegetable marketing channels in Kerinjing Village Agung Lawangan Subdistrict Dempo Utara District Pagar Alam City, (2) analyzing vegetable price fluctuations in Kerinjing Village Agung Lawangan Subdistrict Dempo Utara District Pagar Alam City, (3) calculating the elasticity of vegetable price transmission from consumers to farmers in Kerinjing Village Agung Lawangan Subdistrict Dempo Utara District Pagar Alam City. This research method is a survey methods. The sampling method used for farmer is simple random sampling with a sample of 34 respondents, while the sampling method used for the marketing institutions is snowball sampling with a sample of 10 respondents. The marketing channels are described descriptively, the fluctuation of vegetable price are analyzed using unweighted price index, then analysis of the elasticity of vegetable price transmission using simple linear regression. The result indicated that there are five marketing channels with the most chosen channel pattern is marketing channel 3. The highest vegetable price fluctuations is chicory 54,39 percent, then cabbage 53,62 percent and big red chili is 12,55 percent. Price transmission elasticity of chicory is 1,419 (β>1), cabbage is 0,953 (β<1) and big red chili is 0,689 (β<1), so the vegetable marketing in Kerinjing Village can be said to be inefficient.
Sufis ethics and democracy

Among contemporary Sufi orders (mystical Islamic religious movements), a new political and theological tendency has been developed in the last decades: Sufi counter reformism. Which is a Muslim political-theological movement, inscribed by the Islamic tradition, open to democratic values, and in opposition to Islamic reformism and Islamism. My main hypothesis is that some Sufi orders are playing an important role in the expansion of democratic space in Europe and in the Maghreb. 
In this research, I will investigate the role of Sufi orders as political actors in Belgium, France, Morocco and Algeria.
Sufi counter reformism offers new perspectives on the debate on Islam, democracy, and secularism. It will deconstruct the dichotomist perspective, which opposes secular and religious, private and public, and traditional and modern. 
We need empirical research on Islam, and in particular on Muslim politics, in this period of social and political tensions. 
Finally, this research will give more visibility to the organisations committed to improve democratic rights, by improving and creating new networks, and raising awareness about the debate on Islam and democracy. It will reduce the gap between institutions and citizens, through a better understanding of Islamic democratic engagement, in order to build a more trustful European society.
Cmos compatible and ultra broadband on-chip sic frequency comb

A CMOS compatible and ultra broadband on-chip Silicon Carbide frequency comb (SiComb) is going to be demonstrated for the first time by this project. It is achieved by an interdisciplinary collaboration effort of combing unique optical nonlinearity of SiC, growth of low optical loss SiC thin film and fabrication of high quality factor microresonators. As an enabling technology, the on-chip frequency comb is deemed to have far profound impact on diverse areas of science and engineering, including sensing, timekeeping, distance ranging, searching for exoplanets as well as optical communication. For example, the application of this frequency comb in optical communication as a WDM light source will be demonstrated in this project to show the energy saving and the data traffic handling beyond 100 Tb/s. Compared to frequency combs made from AlGaAs, Lithium Niobate etc, SiC has material sustainability advantages: environmentally friendly, biocompatibility, and extended device lifetime and efficiency, which opens new application potentials. In this ambitious 3-years project, SiComb consortium (7 partners from both academic and industrial sectors) with complementary strengths of SiC material growth, device nanofabrication, nonlinear optics and optical communication systems will collaborate to demonstrate the non-incremental and ground-breaking ultra broadband SiC frequency comb chips, with synergy effect at European level. These results will build leading research and innovation capacity on SiC optical devices and applications across Europe and enhance the competiveness and growth of industrial partners. It will also align with European advancement in frequency comb efforts, as well as innovation competence to position Europe in forefront of technologies in the research and innovation. The future market implementation and utilization is expected to have a strong momentum given by the results and stakeholder establishment in the SiComb project.
Chirurgia dell’obesità: condizioni, interessi e limiti

La chirurgia bariatrica si è sviluppata rapidamente negli ultimi anni grazie alla sua impareggiabile efficacia sulla perdita di peso e nelle comorbilità dell’obesità. Tuttavia, provoca un numero significativo di complicanze, in particolare digestive, nutrizionali e psicologiche che richiedono sia una preparazione pluridisciplinare che un follow-up a lungo termine. La Francia è tra i Paesi che effettuano più interventi, con 60 000 atti all’anno. Il medico di medicina generale si trova quindi necessariamente a confrontarsi con la cura dei pazienti operati. Il suo ruolo è tanto più importante in quanto il numero di persone perse al follow-up dopo chirurgia bariatrica è molto alto, dell’ordine del 50% a 5 anni. Permangono molte incertezze circa l’incidenza e la prevenzione delle complicanze nutrizionali e digestive, con in particolare un rischio di reflusso gastroesofageo e di endobrachiesofago negli interventi restrittivi e un rischio di ostruzione intestinale e di carenze nutrizionali nei casi di derivazione intestinale. Le attuali conoscenze non consentono di considerare un’alternativa alla chirurgia altrettanto efficace nell’immediato futuro. Una migliore organizzazione delle cure e una valutazione delle pratiche sono necessarie per migliorare il rapporto rischio/beneficio.