SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
An innovative topical drug delivery system for improving chronic wound healing

Skin is the largest organ in the human body, forming a protective physical barrier against the outside world. Damages to skin due to physical, chemical and biological factors lead to wounds. While minor wounds heal on their own, chronic wounds (wounds that do not heal within 8 weeks), such as diabetic foot ulcers, subject the patient to significant discomfort and distress while draining the medical system of an enormous amount of resources. Wound healing is a complex, highly regulated process, and complications affect the quality of life of >4 million a year in EU (more than cancer & diabetes) that struggle to live with hard-to-heal injuries, as it can lead to infection, tissue and bone necrosis, pain and in some severe cases even amputation. Stratpharma has developed a range of primary dressings formulated as a silicone-based gel, which can be used on any wounded, damaged, compromised or diseased skin surface. This proprietary film-forming gel is also shown to be an excellent drug delivery system, using which active compounds can be delivered to the wound, thereby enhancing clinical outcomes. Using this property, Stratpharma aims to develop a breakthrough formulation, containing gel and bioglass technology, for improved chronic wound healing. During the phase 1 project, a go-to-market strategy and a supply chain will be established, as well as further development plan will be drafted. Within the overall innovation project, Stratpharma will further test and validate the new formulation, begin clinical trials, implement IP strategy and perform scaling-up activities.
A non-linear analysis of the impacts of natural resources and education on environmental quality: Green energy and its role in the future

Human accomplishments have increased the complexity and interconnectedness of environmental threats, resulting in widespread effects on people, ecosystems, and economies worldwide. In addition to overpopulation, pollution, burning fossil fuels, and deforestation, humans also impact the physical environment in many ways. These changes have contributed to climate change, soil erosion, poor air quality, and undrinkable water. We investigate the linear and non-linear effects of natural resources and education on CO2 emissions in the Latin American (LA) group of nations considering the roles of green energy, foreign remittances, and economic growth from 1990 to 2020. We have developed a comprehensive empirical analysis that applied second-generation advanced econometric methodologies in this study. The results of this research disclosed that natural resources pose a non-linear impact on environmental quality. The low level of natural resources benefits the environment in the LA panel, but higher use of natural resources ultimately intensifies CO2 emissions. Hence, a U-shaped association between natural resources and CO2 emissions is found in the LA panel. In the linear model, natural resources also boost CO2 emissions. Alongside this, education also intensifies CO2 emissions in the selected sample. Green energy and remittances mitigate CO2 emissions and thereby improve environmental quality.
The Contents of Visual Experience

Introduction: Seeing John Malkovich The Content View Why does it matter whether the Rich Content View is true? How can we decide whether the Rich Content View is true? Part I: Contents Chapter 1: Experiences 1.1 States of seeing and phenomenal states 1.2 Visual perceptual experiences Chapter 2: The Content View 2.1 Contents as accuracy conditions 2.2 The Argument from Accuracy 2.3 A flaw in the Argument from Accuracy 2.4 The Argument from Appearing 2.5 Two objections from 'looks', 'appears' and their cognates 2.6 The significance of the Content View Chapter 3: How Can We Discover the Contents of Experience? 3.1 Introspection 3.2 Naturalistic theories of content 3.3 The method of phenomenal contrast Part II: Properties Chapter 4: Kinds 4.1 The examples 4.2 The premises 4.3 Content externalism Chapter 5: Causation 5.1 The Causal Thesis 5.2 Michotte's results 5.3 Unity in experience 5.4 Non-causal contents 5.5 Raw feels 5.6 Non-sensory experiences Part III: Objects Chapter 6: The Role of Objects in the Contents of Experience 6.1 Strong and Weak Veridicality 6.2 The contents of states of seeing 6.3 The contents of phenomenal states 6.4 Phenomenal states: Internalism vs. Pure Disjunctivism 6.5 Why Internalism? Chapter 7: Subject and Object in the Contents of Experience 7.1 Subject-independence and Perspectival Connectedness 7.2 The Good and the Odd 7.3 Complex contents 7.4 Objections and replies Chapter 8: The Strong Content View revisited
Exhaust manifold for internal combustion engine

An exhaust manifold provides improved output by suppressing exhaust interference between cylinders at the exhaust manifold. An air-fuel ratio sensor (5) is installed in position where it can uniformly detect the exhaust gas of each cylinder. The exhaust manifold has a plurality of exhaust tubes (1a, 1b, 1c, 1d), one per cylinder, that connect with a collector case (3). Each of exhaust tubes (1a, 1b, 1c, 1d) has a linear portion (4) located directly above the section where it merges with the collector case (3). The exhaust tubes (1a, 1b, 1c, 1d) are connected to the collector case (3) such that the center axes of the linear portions (4) intersect at intersection point (G) inside the collector case (3) or downstream thereof. The air-fuel ratio sensor (5) is arranged such that its detecting part (5a) is positioned in the vicinity of the intersection point (G). Depending upon whether the exhaust tubes (1a, 1b, 1c, 1d) of cylinders have firing orders that are successive or not determines whether the exhaust tubes (1a, 1b, 1c, 1d) are slanted or parallel with respect to each other.
NON-VOLATILE MEMORY WITH BACKGROUND DATA LATCH CACHING DURING READ OPERATIONS AND METHODS THEREFOR

Part of the latency from memory read or write operations is for data to be input to or output from the data latches of the memory via an I/O bus. Methods and circuitry are present for improving performance in non-volatile memory devices by allowing the memory to perform some of these data caching and transfer operations in the background while the memory core is busy with a read operation. A scheme for caching read data is implemented so that even when the read for a current page on a current wordline must be preceded by a prerequisite read of data on an adjacent wordline, the prerequisite read along with any I/O access is preemptively done in the cycle for reading a previous page so that the current read can be performed while the previously read page is busy with the I/O access.
Residential High-Speed Internet Among Those Likely to Benefit From an Online Health Insurance Marketplace

Using data from the 2013 American Community Survey, we found that 24.3 million people (about 1 in 4) who were either eligible for Medicaid/Children’s Health Inusrance Program (CHIP) or appeared likely to shop for Qualified Health Plan (QHP) lacked residential high-speed Internet. Specifically, 28.6% or 18.9 million people eligible for Medicaid/CHIP and 17.1% or 5.5 million people who appeared likely to shop for a QHP did not have high-speed Internet in the home. For both the Medicaid/CHIP eligible and those likely to shop for a QHP, the proportion of people living in households without Internet varied substantially by race, geography, and other socio-demographic characteristics.
Cyber-Physical systems for pedagogical rehabilitation in special education

The aim of the current MSCA RISE project CybSPEED is to advance a novel framework for analysis, modelling, synthesis and implementation of Cyber-Physical Systems for pedagogical rehabilitation in special education, based on a combination of the best of experience and achievements of the partners in the domains of brain-aware robotics, cognitive biometrics, computational intelligence and reasoning in humanoid and non-humanoid robots for education.  CybSPEED project builds on the results and insights of the recently completed project funded by EEA Grant of Bulgaria and Norway ""METEMSS: Methodologies and technologies for enhancing the motor and social skills of children with developmental problems"" (IR-BAS), on a logical projection of the EU funded project ""Social & Smart"", called “Storytelling NAO” of Spain (UPV/EHU) and on the ongoing research of the project “Special Education Robot Teaching Assistant (EduBot)” of Greece (EMaTTech) funded by the Stavros Niarchos Foudation. CybSPEED project emphasizes the intrinsic-motivational approach to learning by designing human-robot situations (games, pedagogical cases, artistic performances) and advanced interfaces (brain-computer, eye-gaze tracking and virtual reality) where children and students interact with the novel technology to enhance the underlying self-compensation and complementarity of brain encoding during learning. The CybSPEED project aspires to establish as well as to sustain an innovation network across the EU, Japan in the Far East, Chile in South America and Morocco in West Africa that will pursue top-level research on three levels – 1) analysis of cognitive biometrics signals, 2) modeling of the learner-robot interaction and 3) development of novel instruments toward an optimal design of Cyber-Physical Systems for improved pedagogical rehabilitation in education.
Application of microdialysis for elucidating the existing form of hyperoside in rat brain: Comparison between intragastric and intraperitoneal administration

Hypericum perforatum (St. John's wort) is an important anti-depressant herb used in clinic and commonly prescribed for mild depression. Hyperoside is one of the major components of H. perforatum and is also detected in many plant species such as Abelmoschus manihot, Black Currant, Rosa agrestis, Apocynum venetum and Nelumbo nucifera.As the hyperoside showed CNS (central nervous system) protective activity (e.g. anti-depressant-like effect), the possibility of hyperoside or its metabolites to reach CNS should be investigated. Moreover, the pharmacokinetics profile of hyperoside or its metabolites in rat brain should be studied for further elucidating the mechanism of hyperoside action on CNS.A simple method for simultaneous determination of unbound hyperoside and its metabolite 3'-O-methyl-hyperoside in rat brain was developed by using ultra-high performance liquid chromatography coupled with tandem mass spectrometry (UPLC-MS/MS) and microdialysis technique. This method was applied for pharmacokinetics study of hyperoside and 3'-O-methyl-hyperoside in rat brain after intragastric (i.g.) and intraperitoneally (i.p.) administration of hyperoside in vivo.Results showed that neither hyperoside nor its metabolites were detected in rat brain after i.g. administration but both compounds could be detected after i.p. administration. Considering the activity of hyperoside through both i.g. and i.p. administration, our results imply that the active components of hyperoside in vivo might be different. Therefore, further studies are needed to identify the active components of hyperoside in vivo through these two different routes. Moreover, non-oral administration route (e.g., i.p.) should be further investigated and be explored to obtain higher bioavailability and better activity for hyperoside. Our results also showed that the real existing form of hyperoside in rat brain were hyperoside and its methylated metabolite with maximum concentration to be 63.78 ng/mL and 24.66 ng/mL after 20mg/kg i.p. administration, respectively. Therefore, a more reasonable concentration of hyperoside should be considered in in vitro assay to reflect the real situation of hyperoside concentration in vivo.Due to the wide use of herbal remedies containing hyperoside, our investigation will contribute to further clarifying the action of this substance. Moreover, this method will be applied for clinical pharmacokinetics study of hyperoside and its metabolite as well as herbs that contain hyperoside.
Work – Cooperation on advanced calculations in Europe

Help programme reference_number: ___ SA.52867(2019/X) – Institute of Bioorganic Chemistry of the Polish Academy of Sciences; SA.52868(2019/X) – AGH University of Science and Technology; SA.52869(2019/X) – Gdańsk University of Technology; SA.52870(2019/X) – Wrocław University of Technology; SA.52871(2019/X) – Czestochowa University of Technology; SA.52872(2017/X) – Białostock University of Technology; SA.52875(2019/X – Świętokrzyska University of Technology; SA.52876(2019/X) – Lodz University of Technology Purpose of public aid:_art. 26 The PRACE-Lab project was posted on the Polish Road Map of Research Infrastructures. The European counterpart of the project is PRACE (Partnership for Advanced Computing in Europe), which is also included in the current edition of the European Commission’s ESFRI Roadmap. The main objective of the project is to provide advanced computing services HPC (High Performance Computing) and data for the scientific community in Poland and Europe, as well as to enable calculations in the field of industrial research. In addition, the overarching objective is to improve the position on European and global markets of the Polish ICT sector by supporting and strengthening the development of innovative solutions in cooperation with the private sector, with particular emphasis on SMEs, with the science sector.
De victorias o derrotas: El metro, de Donato Ndongo-Bidyogo

Abstract El metro (2007), the most recent novel by the Equatoguinean author Donato Ndongo, ends with the failure of the immigrant experience for its African protagonist. I argue that the blurring of gender difference and a relationship with the world based on male competition leads to this ending of the novel in a fundamental manner. This text reflects an identity conflict in an African male individual, Lambert Obama Ondo, who relates to white men in terms of victory or defeat. Both black and white women have a subsidiary role. In this scenario, there is no possibility of conquest for Lambert, since he comes from a poor country and cannot count on a corrupt government to confront neocolonial exploitation. Finally, as an illegal Black African immigrant in Spain who has to endure racism and social vulnerability, he will not have a chance for a sound victory over white men. He will end being a victim, but at least a heroic one.
Ff4Eurohpc: hpc innovation for european smes

The FF4EuroHPC proposal addresses the need for outreach to, and support of, Europe’s Small and Medium-sized Enterprises (SMEs) in order that they can profit from the innovation advantages offered by advanced High Performance Computing (HPC) technologies and services. FF4EuroHPC takes core team members from the highly successful Fortissimo and Fortissimo-2 projects (hereinafter simply Fortissimo projects) which executed 92 business experiments.  They will use the lessons learned and best practices developed in those projects to create a portfolio of business-oriented “application experiments” that allow agile SMEs to investigate and solve business challenges and develop innovative business opportunities. The application experiment framework ensures that they receive the necessary, appropriate support to enter into the HPC ecosystem. FF4EuroHPC will lower the barriers for the participating SMEs to commence HPC-related innovation in their existing or newly identified markets either by using HPC systems for their business needs or by providing new HPC-based services. The outcome will be improved design and development processes, better products and services, and improved competitiveness in the global marketplace. Fundamentally, FF4EuroHPC is focussed on the creation of economic growth and jobs for the European Union.
Modelling the european data economy

The Modelling the European Data Economy (EuDEco) project will assist European sci-ence and industry in understanding and exploiting the potentials of data reuse in the context of Big and Open Data big data. The aim isto establish a self sustaining data market and thereby increase the competitiveness of Europe. To be able to extract the benefits of data reuse, it is crucial to know how to understand the underlying economic, societal, legal, and technological framework conditions and challenges to build useful applications and services. Despite the amount of activities in this domain, an effort is missing to develop use cases and business models that are economic viable, legally certain and taking societal needs and concerns into account.

EuDEco will accomplish this by leveraging the engagement of other projects conducting pilots on data reuse as well as by the engagement of external experts and stakeholders. EuDEco moves beyond the classical approaches by applying the approach of complex adaptive systems to model the data economy in order to indentify value networks, use cases and business models for data reuse. In the course of the project will develop and refine the data economy model in several steps further by case studies on previous pilots on data reuse, by in-depth analysis from legal, socioeconomic and technological point of view, and by extensive tests of use cases and business models with other projects. Therefore it will analyse framework conditions relevant and challenges related to data reuse and the emergence of a self-sustaining data market.

Finally, EuDEco will deliver a model of the data economy including viable use cases and business models as well as suggestions and recommendations addressing the main legal, contractual, societal, and technological concerns and challenges such as contractual framework or data protection. Above that EuDEco will develop an observatory for policy makers enabling them to track the development of the data economy.
Ratiometric Biosensor for Aggregation-Induced Emission-Guided Precise Photodynamic Therapy

Photodynamic therapy faces the barrier of choosing the appropriate irradiation region and time. In this paper, a matrix metalloproteinase-2 (MMP-2) responsive ratiometric biosensor was designed and synthesized for aggregation-induced emission (AIE)-guided precise photodynamic therapy. It was found that the biosensor presented the MMP-2 responsive AIE behavior. Most importantly, it could accurately differentiate the tumor cells from the healthy cells by the fluorescence ratio between freed tetraphenylethylene and protoporphyrin IX (PpIX, internal reference). In vivo study demonstrated that the biosensor could preferentially accumulate in the tumor tissue with a relative long blood retention time. Note that the intrinsic fluorescence of PpIX and MMP-2-triggered AIE fluorescence provided a real-time feedback which guided precise photodynamic therapy in vivo efficiently. This strategy demonstrated here opens a window in the precise medicine, especially for phototherapy.
Role of Quality Attributes of Indian Wool in Performance of Woolen Product: Present Status and Future Perspectives - A Review

Wool, a natural animal fibre obtained from fleece of small ruminants mainly from sheep and is used for development of various textile products ranges from suiting fabric to carpet due it its distinct properties like resiliency, flame-resistance, warmth, and good reactivity towards dyes. The quality attributes such as physio-chemical, mechanical and morphological properties of wool fibre play a major role in deciding its end use and value addition. Generally, fine wool is used for making suiting fabric with shrink resistant finish; Indian wool can be utilized for carpets and blankets. However, there is a wide scope for product diversification from Indian wool through genetic and technological intervention for improving their aesthetic as well as performance properties. This paper reviews the role of important quality attributes of Indian wool for the product development and value addition.
Increasing the competitiveness, resource efficiency and efficiency of “Inert Materials 2012” Ltd.

The company “Inert Materials 2012” Ltd. was registered in 2012. The main activity of “Inert Materials 2012” Ltd. is: production of aggregates, crushed fraction, ballast and felt and provision of services with specialised equipment. The main challenges facing the company are linked to the traditionally strong competition in the industry and the increased consumption of construction materials in different types of construction, as well as to the applicant’s aspiration to gain more stable market positions and expand production. The introduction of new requirements and standards in construction invariably leads to changes and developments in the market for the construction materials used therein. This requires continuous expansion of production capacity and product range, with full quality control and maintaining competitive prices. The main constraints of the company are related to insufficient production capacity with increasing needs and requirements in the building materials market and the need to introduce modern technologies and equipment, which will enable the company to expand its operations, increase production capacity and optimise production processes, achieve sustainable competitiveness in the long term. This project will overcome the above-mentioned problems for the company by purchasing modern energy-efficient and resource-efficient equipment, which will increase the competitiveness of the company. The project will have a duration of 18 months, a budget of BGN 1 064 640. The project will be implemented through external procurement in accordance with Council of Ministers Decree No 118/20.05.2014.
Meteo-hydrological Forecast and Observations for improved water Resource management in the ALPS

The project will improve and integrate instruments to support the management of environmental resources in alpine areas, in particular water. This goal will be achieved by adopting innovative techniques for monitoring and reconstructing the time evolution of meteo-hydrological processes.
The competence areas of the partners cover uniformly the central-eastern Alps, where the territories of various countries and regions intertwine, thus requiring a transnational and interregional approach to issues faced by the project.
Climatic databases of variables relevant for water resources availability will be collected and analysed. Pilot activities at selected target areas will be performed, such as use of microradars and numerical modeling of meteorological and rainfall-runoff processes. The above actions will be preliminary to operational activities.
Evaluation of social and financial impact of improved meteo-hydrological information will stimulate the adoption of best practices of sustainable planning.