SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Social protection innovative investment in long term care

SPRINT project intends to give meaning to the concept of social investment as applied to long-term care provision.  Its objective is to articulate in more detail the aspirations of the Social Investment Programme, to provide a means for assessing the social costs and benefits of various ways of providing long-term care for the frail elderly, and to present examples of approaches that do indeed, facilitate provision in a way that social benefits are achieved. More specifically, SPRINT will: identify the current landscape of organisation and resourcing of LTC in Europe in order to understand the place in the discussion that social investment currently has and how the principles of social investment used to improve provision in a fashion that is welfare enhancing; investigate how the different resourcing and delivery forms of LTC create social and economic returns, outcomes and social impact and to determine their success factors; evaluate the fiscal and social costs and benefits of various national approaches to LTC delivery; establish a common vocabulary for social investing and for the financing mechanisms of long-term care; identify the most appropriate frameworks for the definition and analysis of social impact of LTC programmes; define the principles for incorporating social considerations in funding decisions of LTC policies and to analyse their relationship with the social innovations addressing the challenges of demographic ageing and of inequities in access to care; develop appropriate instruments, such as the Feasibility Framework Tool, the assessment scales, thresholds and the Impact Map, which will ensure successful implementation of investment in LTC by public authorities, social insurance funds and private investors; create a model of investment in the care sector, emphasizing in social innovations that will be correlated with the broad economic policies;  and propose reforms at policy levels.
New operational sensing system

Organized crime investigation can greatly benefit from the availability of very small, concealable sensing devices to monitor, record and communicate criminal activity to remote surveillance stations. Acquired data can be used as proof in Courts of Justice only if the sensing device, the communication channel and the monitoring station are tamper proof and comply with all legal, integrity and chain-of-custody requirements. 
The NOSY project is focused on the development of a miniaturized yet highly sensitive platform, for the detection of illicit or suspicious substances. The platform includes the development of a miniature sensing device, a monitoring station and communication infrastructure for LEA network integration. The enabling technology of the system is an innovative microelectronics sensor that combines state of the art micro and nanotechnologies with advanced smart sensing materials, which will be integrated as part of the project. In addition there will be the development of complete devices for both stand alone and embeddable monitoring and recording. A critical requirement is that the recorded or transmitted data to be usable as proof in Court. The device will include proofing from any type of external tampering; the communication channel will be secure, compliant and integrated into the existing LEA data networks. As deemed necessary by LEAs, the project will develop prototype products to help tackle illegal drug trafficking and development of homemade bombs. Accurate and unambiguous identification of substances is fundamental to allow LEA to intervene with the most suitable action or counter measure. LEAs will be involved at all critical milestones of the project, from initial requirements, to a first prototype validation, to the extensive trial phase. The project will also propose a certification process tailored to the new sensing devices to enable their legal validation for forensics use while in compliance with European privacy requirements.
Development of CITO-LAB diagnostic laboratory for medical and health tourism services

The project is in line with the objectives of Priority Axis 2 CONCERNING ECONOMY and the specific objective of Sub-measure 2.5. Because thanks to financial support in the form of grants, it contributes to increasing the application of innovation in enterprises in the SME sector and increasing the use of ICT in enterprise activities. This is due to the fact that the project will result in the introduction of product, process innovation at national level. Better conditions for the development of SMEs in the laboratory diagnostic services market will be achieved through the purchase of specialised laboratory equipment and software, enabling the introduction of 1 new diagnostic service and a significant improvement of current diagnostic services. The result of the project will be one (1) company receiving support and a grant (CI 1 and CI 2), supported to introduce new products for the company (CI 29) and new for the market (CI 28). As part of the project, a specialised andrological clinic and a laboratory performing semen examination based on computer analysis and a food intolerance analysis cell and an allergology laboratory will be launched. The project is carried out in the field of advanced technology — the medical, precision and optical industries. The project fits into regional specialisations — Medical Tourism. The aim of the project is to create at least 3 new jobs for K. and M. [CI 8], including 2 for women and 1 for men. The measures taken by the Applicant included obtaining offers from manufacturers and suppliers of medical equipment and publicly available laboratory software to prepare a cost estimate. The total value of the investment will be PLN 29870.55 (CI 6). The direct recipients of the products implemented under the project are residents/medical tourists/from all over Poland. The contribution of privatisation measures was reduced by 15 pps.
다양한 신체사이즈를 고려한 사무용의자 대량맞춤생산 지향 모듈화 설계방법론

Modular design is a very important design methodology that allows designers to develop a product family at low product development and production cost. This design methodology is also very powerful for products that require frequent design changes due to customer requirements. Most research on modular design is focused on the modularization based on functional decomposition, physical interface and manufacturing process of parts. In this paper, we propose a modularization method that takes size of human body parts into consideration for products which have physical interactions with the products such as office chairs and sport machines. Evaluation of modular design is based on dependence measurement between every pair of components in the design. In addition we proposed a module sizing method for the maximization of customer satisfaction in MC(Mass Customization) environment.
Increased rates of infantile hypercalcaemia following guidelines for antenatal vitamin D3 supplementation

Consultations for infantile hypercalcaemia (IIH) have increased at Sydney Children’s Hospital since guidelines for vitamin D3 supplementation during pregnancy were introduced in 2006. Recent nationwide shortages of low-calcium formula (LCF) suggest this problem may be widespread. CYP24A1 mutations have been identified as a potential cause of IIH.

To determine if IIH is occurring more commonly, de-identified, first-measured serum calcium from all infants <6 months (n=5796) measured in our laboratory, were grouped by years 2005-2007 (n=1516), 2008-2010 (n=1945) and 2011-2013 (n=2335). In addition, we analysed 13 infants treated by our department for idiopathic infantile hypercalcaemia (IIH) from 2011-2013.

Rates of hypercalcaemia (>2.75mmol/L) increased from 2011 (1.1% vs 1.3% vs 8.7%, χ2P<0.001). Rates of hypocalcaemia (<2.25mmol/L) fell steadily (42.4% vs 32.3% vs 24.8% %, χ2P<0.001). Twelve mothers of our 13 infants with IIH received antenatal vitamin D3 supplementation. One infant also received 400 units/day Vitamin D3 post-natally. At diagnosis, median age was 13 days (range 4-50), 77% were breast-fed, 54% were symptomatic and 25% had nephrocalcinosis. Median initial calcium was 3.00mmol/L (range 2.84-4.03) and phosphate 2.04mmol/L (1.1-3.33). PTH was not elevated (median 1.0pmol/L [<0.3-3.1]), urinary calcium: creatinine ratio not suppressed (median 2.3, [0.4-9]), 25OHVitD low-normal (median 44nmol/L [17-218]) and 1,25(OH)2VitD elevated (median 232pmol/L [64-720]), in keeping with an abnormality in CYP24A1. In 7/10 infants with data available, treated with LCF for median 95 days (range 25-310), median PTH rose to 17.1pmol/L ([8.2-49.3], P=0.02) with a trend to lower 25OHVit D (median 23nmol/L [<10-108], P=0.09) despite continued high-normal calcium levels (median 2.66mmol/L [2.11-2.75]).

Concurrent changes in rates of hyper and hypo-calcaemia suggest antenatal vitamin D3 supplementation as an aetiological factor. IIH was associated with significant morbidity, including symptomatic hypercalcaemia and nephrocalcinosis. Treatment with LCF prevented further symptomatic hypercalcaemia, but resulted in elevated PTH. The biochemistry of our patients with IIH raises variations in Vitamin D metabolism or calcium set-point as potential associated factors.
An Analysis of Gender-Role Stereotyping in the Illustrations of Middle School Science Textbooks Developed under the 2007 Revised National Curriculum

이 연구에서는 2007 개정 교육과정에 의한 중학교 과학 교과서 27권의 삽화를 성역할 고정관념의 측면에서 분석하고, 그 결과를 7차 교육과정에 의한 중학교 과학 교과서와 비교하였다. 삽화의 유형을 분류한 후, 삽화에 등장하는 학생과 성인의 성별 등장 빈도, 활동 유형 및 행동 특성의 성별 빈도를 분석하였다. 7차 교육과정기에 비해 모든 분석 항목에서 성별에 따른 차이가 감소하였으나, 학생의 학습 활동과 학생 및 성인의 행동 특성을 제외한 모든 항목에서 여전히 성역할 고정관념이 나타났다. 남학생의 등장 빈도는 여학생보다 많았는데, 학생의 학습 활동에서는 성별 빈도가 균형을 이루고 있었으나 학습외 활동은 남학생을 중심으로 묘사되어 있었다. 성인의 경우에는 남성이 여성보다 많이 등장하였고, 가정 활동에서는 여성의 비율이, 가정외 활동에서는 남성의 비율이 우세하였다. 직업 활동에는 남성이 주로 묘사되어 있었다. 학생과 성인은 대부분 적극적 행동 특성을 보였고, 학생과 성인 모두 각 성별 내에서 행동 특성의 비율이 비교적 유사하였다. In this study, the illustrations of 27 middle school science textbooks developed under the 2007 Revised National Curriculum were analyzed in the aspect of gender-role stereotyping, and the results were compared with those of the 7th National Curriculum. The types of the illustrations were classified, and the frequencies of pupils and adults who appeared on the illustrations were counted by gender, and the types of activities and the character of them were also analyzed by gender. In all results of the analyses, the differences between male and female decreased in comparison with those of the 7th National Curriculum. More male pupils appeared in the illustrations than female pupils. The frequencies of learning activities were balanced by gender, but other activities were described as focusing on male pupils. The frequencies of male adults outnumbered female adults. While the ratio of female adults was high in houseworks, that of male adults was high in outdoor activities. The jobs of adults were also illustrated as male-centered. Most pupils and adults were found to be active. Both ratios of pupils and adults for each gender were relatively similar.
Learner construction of corpora for general English in Taiwan

This exploratory study describes a framework for data-driven learning (DDL), inGeneral (non-major) English university classes, in which learners construct linguistic corpora instead of merely consulting them. Prior related work has addressed the needs of language specialists, in particular trainee translators who are learning how to compile glossaries, rather than non-major students of English. It is argued in this article that the process of creating a corpus inculcates a sense of ownership in the learner and therefore has a motivational impetus. This is especially true, it is claimed here, when the topic of the corpus is of personal interest to the learner, or coincides with their major field of study. Learners may pursue language study for only a short period of their university career, but once the corpus is constructed, some students may be sufficiently motivated to consult it and add to it when needed. Moreover, the process of compiling the corpus may lead to the acquisition of not only language but...
Monitoring Si growth on Ag(111) with scanning tunneling microscopy reveals that silicene structure involves silver atoms

Using scanning tunneling microscopy (STM), the elaboration of the so-called silicene layer on Ag(111) is monitored in real time during Si evaporation at different temperatures. It is shown that the growth of silicene is accompanied by the release of about 65% of the surface Ag atoms from the Si covered areas. We observe that Si islands develop on the Ag terraces and Si strips at the Ag step edges, progressively forming ordered (4×4), (13×13) R13.9°, and dotted phases. Meanwhile, displaced Ag atoms group to develop additional bare Ag terraces growing round the Si islands from the pristine Ag step edges. This indicates a strong interaction between Si and Ag atoms, with an important modification of the Ag substrate beneath the surface layer. This observation is in contradiction with the picture of a silicene layer weakly interacting with the unreconstructed Ag substrate, and strongly indicates that the structure of silicene on Ag(111) corresponds either to a Si-Ag surface alloy or to a Si plane covered with ...
A sensor-based control strategy for the correction of growth abnormalities

Corrections for growth abnormalities using robotic and computer-aided treatments is a common practice in the medical profession. However, for many therapeutic applications, therapists may use their best judgement in adjusting equipment such as casts or braces. Using the correction of a condition called plagiocephaly in infants as a case study, we provide a corrective, sensor-based control strategy to guide physicians in more accurately correcting for growth abnormalities. In conjunction with an ellipsoidally-shaped mesh-representation of the skull in which the sensors are nodes, we use Model Reference Adaptive Control to regulate the node positions to converge to those of an ideal growth trajectory. We do this both when the error dynamics between the actual and desired systems are known and when they are unknown. We have shown that using a parameter-based adaptation law, stability is achieved in parameter estimation and state convergence; however, when the error dynamics are unknown, stability is only guaranteed for a certain range of control gains. These results show great promise for aiding physicians in more accurately caring for cranial and similar deformalities that occur in infants.
Impact of adaptive iterative dose reduction (AIDR) 3D on low-dose abdominal CT: comparison with routine-dose CT using filtered back projection

Background While CT is widely used in medical practice, a substantial source of radiation exposure is associated with an increased lifetime risk of cancer. Therefore, concerns to dose reduction in CT examinations are increasing and an iterative reconstruction algorithm, which allow for dose reduction by compensating image noise in the image reconstruction, has been developed. Purpose To investigate the performance of low-dose abdominal CT using adaptive iterative dose reduction 3D (AIDR 3D) compared to routine-dose CT using filtered back projection (FBP). Material and Methods Fifty-eight patients underwent both routine-dose CT scans using FBP and low-dose CT scans using AIDR 3D in the abdomen. The image noise levels, signal-to-noise ratios (SNRs), and contrast-to-noise ratios (CNRs) of the aorta, portal vein, liver, and pancreas were measured and compared in both scans. Visual evaluations were performed. The volume CT dose index (CTDIvol) was measured. Results Image noise levels on low-dose CT images using AIDR 3D were significantly lower than, or not significantly different from, routine-dose CT images using FBP in reviewing the data on the basis of all patients and the three BMI groups. SNRs and CNRs on low-dose CT images using AIDR 3D were significantly higher than, or not significantly different from, routine-dose CT images using FBP in reviewing the data on the basis of all patients and the three BMI groups. In visual evaluation of the images, there were no statistically significant differences between the scans in all organs independently of BMI. The average CTDIvol at routine-dose and low dose CT was 21.4 and 10.8 mGy, respectively. Conclusion Low-dose abdominal CT using AIDR 3D allows for approximately 50% reduction in radiation dose without a degradation of image quality compared to routine-dose CT using FBP independently of BMI.
Evaluation of groundwater contamination sources by plant protection products in hilly vineyards of Northern Italy

Abstract In Europe, 25% of groundwater has poor chemical status. One of the main stressors is agriculture, with nitrates and plant protection products (PPPs) causing failure in 18% and 6.5%, respectively, of groundwater bodies (by area). EU legislation for the placement of the PPPs on the market is one of the most stringent in the world. However, recent monitoring studies in hilly vineyards of Tidone Valley, north-west of Italy, show presence of PPPs used for grapevine cultivation in 15 out of 26 groundwater wells monitored, at values above the Environment Quality Standard (EQS) for groundwater (0.1 μg/L). However, no information about the contamination sources are available. Therefore, the objective of the present work is to evaluate the groundwater contamination sources by PPPs, in a small catchment with intensive viticulture, by collecting and integrating monitoring data, sub-surface water movement data and territorial characteristics. The results show that in wells used for PPP's mixture preparation and sprayer washing located at the top of hilly vineyards, with low slope and no water movement in the surrounding soil, the contamination is most likely from point sources. On the contrary, for wells located in a fenced area at the bottom of the hill, far away from vineyards and being used for drinking water production, the contamination is most likely from diffuse sources. Our results were used to raise awareness on groundwater contamination from PPPs among farmers in the study area; moreover a waterproof platform for sprayers washing, equipped with wastewater recovery and disposal system, able to avoid point-source contamination, was implemented in a local demonstration farm. Several demonstration activities were then organised with the farmers of the entire Valley in order to show its functionality and promote its diffuse use.
Vecmap ipm, a one-stop-shop for the sustainable prevention of urban pests of public health importance

You might assume that pest-borne diseases are relics that belong to the past, but you can’t ignore that mosquito’s, ticks, rodents, fleas, bedbugs, cockroaches and several other very well know pests are often bothering you. And surely you did not remain unaffected when the news about Zika virus, spread during the latest Olympic games, was threatening the future lives of unborn children. We currently witness important changes in ecology, climate & human behaviour that favour the development of urban pests. Global travel and trade, urbanisation and environmental challenges are causing pest related human diseases to emerge. Avia-GIS is aiming to prevent pests from disturbing our lives wherever we are! Most pest controllers still limit their interventions to reactive control using harsh chemicals in a ‘carpet bombing’ setting despite EU regulations 2014, imposing to revert to proactive Integrated Pest Management (IPM) principles. Avia-GIS is a leading Belgian innovative SME established in 2001 who has built research and public authority trust over the past 17 years and developed a unique, disruptive software suite - VECMAP® - that will support society to overcome one of its important health threats, the spreading of Pests of Public Health importance. Avia-GIS grew steadily by 17% per year, having now an annual turn-over of 2M€ and employing 15 highly specialised staff members. With the help of the H2020 Instrument, we will be able to add IPM functionalities and bring VECMAP®IPM to the market. Within 5 years Avia-GIS will enable 3.200 SME pest controllers and 3.600 local authorities to shift to IPM strategies. With the grant we will raise revenue from 2 M€ to 22 M€ in 2023 and headcount from 15 to 58 in 2023 and contribute to the scaling of 7 resellers in Europe. The H2020 grant is an essential component of our second investment round that will allow us to attract the needed additional private investment money upon signature of the EC grant.
Great Plains polygonal fault system as expressed in Saskatchewan: Late Cretaceous fault initiation and graben formation

An extensive polygonal fault system (PFS) has been recognized in fine-grained Late Cretaceous sediments of the Western Interior Seaway of North America. Polygonal fault systems are pervasive organizations of nontectonic faults with fault traces that coalesce to form distinctive polygonal fault patterns. Interpretation of a three-dimensional seismic dataset from southeast Saskatchewan provides insight into fault initiation, timing, and geometry for the Great Plains PFS (GPPFS). Faulting initiates in the Niobrara Formation, with the largest fault throws occurring over Early Cretaceous Viking Formation sandstone accumulations, suggesting that drape compaction over the channel sand initiated some of the faulting. Above this, faulting increases in vertical offset, and the predominant fault strike angles change in the Lea Park, Belly River, and Bearpaw formations (all homotaxial to the Pierre Shale) throughout Campanian time. By late Bearpaw time, the initially almost random fault strike orientations change to well-defined northwest–southeast- and west–east-striking grabens. These grabens have up to 20 m of throw and can be 125 m wide and 900 m long at ∼400 m current depth. Predominant graben faults are the continuation of some of the deeper PFS faults. Moreover, the grabens are present over a Campanian clinoform bed and may be interpreted to indicate Bearpaw time extension tectonics that is local or regional in scale. The PFS helps to explain near-surface faulting observed in Late Cretaceous sediments in the Western Interior Seaway and could be used as a model to help explain Late Cretaceous geology, subsurface groundwater flow, and shallow natural gas reservoir continuity.
Allostery in drug discovery

Most current drugs are designed to bind directly to the primary active sites (also known as orthosteric sites) of their biological targets. Allosteric modulators offer a powerful yet underexploited therapeutic approach. They can elicit a richer variety of biological responses and, since they target less conserved binding sites, higher selectivity and less adverse effects may be obtained (Changeux, Drug Disc Today 2013). This proposal aims to train a new generation of scientists in exploiting the concept of allostery in drug design, putting together a whole array of technologies to identify and characterize allosteric modulators of protein function that will be applied to therapeutically relevant systems. Our approach is based on a combination of experimental and simulation techniques, including fragment Screening with structural characterization (X-ray, NMR, H/D exchange), proteomics (MS/MS), ITC, DNA encoding libraries, Virtual Screening, Molecular Dynamics simulations-based methods, Synthetic Chemistry, and in vitro and cellular assays for the verification of results. It should also be noted that allosteric targeting need not be achieved solely through the design of synthetic small molecules but also can also be reached via conformationally specific allosteric antibodies, which represents an important field of future research. There are already clear examples of monoclonal antibodies that allosterically target ion channels (Lee et al., 2014b), GPCRs (Mukund et al., 2013), and RTKs (De Smet et al., 2014), as well as cytokine and integrin receptors (Rizk et al., 2015; Schwarz et al., 2006).