SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Upgrading the Neutron Radiography Facility in South Africa (SANRAD): Concrete Shielding Design Characteristics

Abstract A common denominator of all neutron radiography (NRAD) facilities worldwide is that the perimeter of the experimental chamber of the facility is a radiation shielding structure which,in some cases, also includes flight tube and filter chamber structures. These chambers are normally both located on the beam port floor outside the biological shielding of the neutron source. The main function of the NRAD-shielding structure isto maintain a radiological safe working environment in the entire beam hall according to standards set by individual national radiological safety regulations. In addition, the shielding's integrity and capability should not allow, during NRAD operations, an increase in radiation levels in the beam port hall and thus negatively affectadjacent scientific facilities (e.g. neutron diffraction facilities).As a bonus, the shielding for the NRAD facility should also prevent radiation scattering towards the detector plane and doing so, thus increase thecapability of obtaining better quantitative results. This paper addresses Monte Carlo neutron-particletransport simulations to theoretically optimize the shielding capabilities of the biological barrierfor the SANRAD facility at the SAFARI-1 nuclear research reactor in South Africa. The experimental process to develop the shielding, based on the principles of the ANTARES facility, is described. After casting, the homogeneity distribution of these concrete mix materials is found to be near perfect and first order experimental radiation shielding characteristicsthrough film badge (TLD) exposure show acceptable values and trends in neutron- and gamma-ray attenuation.
A novel konjac glucomannan-xanthan gum binder for aquaculture feeds: the effect of binder configuration on formulated feed stability, feed palatability and growth performance of the Japanese abalone, Haliotis discus hannai

As part of a programme to develop sustainable diets for macroalgivores, a 3-month experiment was conducted to determine the effects of konjac glucomannan–xanthan gum (KX) binder configuration on formulated feed stability, feed palatability and growth performance of juvenile, hatchery-reared, Haliotis discus hannai. This study was conducted in a recirculation facility in which four KX binder configurations were evaluated in a series of isonitrogenous experimental feeds and freshly harvested Laminaria digitata was included as a natural feed type. Dry matter leaching of the experimental feed treatments was assessed with no significant difference in the dry matter leaching between treatments observed. No differences (P > 0.05) were found in percentage survival, daily food consumption (DFC) and linear growth rate (LGR) between treatments. Food conversion efficiency (FCE), specific growth rate (SGR) and body weight/shell length (BW/SL) ratio were significantly higher when offered L. digitata. Trends showed that the best performing KX feed in terms of FCE, LGR, SGR and BW/SL ratio was produced with the 2% KX; 1 : 1 binder.
TARGET CLASSIFICATION WITH LOW-RESOLUTION SURVEILLANCE RADARS BASED ON MULTIFRACTAL FEATURES

The multifractal characteristics of return signals from aircraft targets in conventional radars ofier a flne description of dynamic characteristics which induce the targets' echo structure; therefore they can provide a new way for aircraft target classiflcation and recognition with low-resolution surveillance radars. On basis of introducing the mathematical model of return signals from aircraft targets in conventional radars, the paper analyzes the multifractal characteristics of the return signals as well as the extraction method of their multifractal features by means of the multifractal analysis of measures, and puts forward a multifractal-feature-based classiflcation method for three types of aircraft targets (including jet aircrafts, propeller aircrafts and helicopters) from the viewpoint of pattern classiflcation. The analysis shows that the conventional radar return signals from the three types of aircraft targets have signiflcantly difierent multifractal characteristics, and the deflned characteristic parameters can be used as efiective features for aircraft target classiflcation and recognition. The results of classiflcation experiments validate the proposed method.
Enabling malaria rhomboid proteases as drug targets: usage of molecular cookie cutters to shape novel activity assays and inhibitors.

Rhomboid proteases from P. falciparum, the causative agent of malaria, play a role in invasion of human red blood cells. The exact role of the individual members is challenging to track, because of difficulties in genetic manipulation of the P.falciparum and the inviability of some loss-of-function mutants. Hence, a chemical strategy is an attractive alternative. Unfortunately, the study of these eukaryotic rhomboids (PfROMs) has rendered impractical to date.

The bottleneck is that the current purification techniques use detergents that eliminate the physiological membrane, yielding low enzyme stability and activity. In its turn, this rules out the use of activity assays and chemical probes to study their function. Encapsulating these proteins in their lipid environment will address these shortcomings. I will develop a detergent free purification method, based on a styrene maleic acid (SMA) polymer that functions as a “molecular cookie cutter”, creating SMA-lipid-protein nanodiscs, which retain their biological properties upon purification.

Using this “molecular cookie cutter” to create lipid nanodiscs, I will isolate PfROMs and develop activity assays in order to identify and optimize novel inhibitors. The most potent and selective candidates will be evaluated in a malaria invasion model to verify the druggability of malaria rhomboids. Furthermore, these novel compounds may serve as leads for a new generation of therapeutic agents.

The straightforward expansion of our approach to other intramembrane proteases may be the game-changer for drug discovery and future therapeutics directed against rhomboids from other species.
THEFT-PREVENTION DEVICE FOR MOTORCYCLES, QUADS, SCOOTERS AND THE LIKE

The present invention comprises, principally, an anti-theft chain formed by links and covered on the outside by a protective cover, to one of the ends of which a locking terminal is secured, preferably to the fixing pivot of the end of the handlebar, and at the opposite end the anti-theft chain incorporates a terminal for fixing to a fixed point of the chassis. Said fixing terminal is adapted so that it can be anchored to a plate secured to the vehicle chassis by a bush secured to said plate, the fixing terminal comprising a coupling unit that is inserted and held inside the bush, such that the coupling unit is able to rotate freely about the longitudinal axis of the bush, between two limit positions, and, furthermore, in a specific rotation position said coupling unit is adapted so that it can be removed from the bush, and thus the chain can be withdrawn from the anti-theft supports.
Effective and resource efficient cleaning system for x-ray personal protective equipment (ppe)

RealStar S.r.l., the worldwide leader in the manufacture of innovative high quality dry-cleaning machinery, with 198 employees and a turnover of 46 MLN €, and SIMAD S.r.l., a consolidate player in the X-ray Medical Technology sector, with 13 employees and a turnover of 3 MLN €, have developed, together, CLEANI-Rad, an innovative system to completely disinfect, in an automatic way, lead aprons used in hospitals to protect surgeons and patients against radiation, avoiding damages in the lead film, what results in an increase of the security for users reducing X-Ray exposure and risks coming from infections thanks to the total cleaning. Moreover, it does not exist direct contact between users and contaminants. This also means economic savings due to the reduced infection costs, that nowadays suppose 65 billion € annually in Europe, and new personal protective equipment investments. CLEANI-Rad its effective and resource efficient, as it supposes water savings, compared to hand-washing method, thanks to its water filter’s system, and a reduced amount of lead discharged to the environment (about 21 Kg/year per each 150 lead aprons). In addition, CLEANI-Rad is equipped with an innovative software that register every washing operation optimizing the control and maintenance of the lead aprons.
A technological platform to combat cancer therapy resistance

The development of resistance to cancer therapy is one of the most frequent reasons for the failure of anti-cancer treatments. Therapy resistance is linked with tumor-recurrence and has devastating consequences for the clinical outcome of the individual patient and causes increased costs for public health systems. The understanding of mechanisms of resistance-formation and the development of strategies directed towards the resensitization of resistant tumor cells to cancer therapy represents one of the most important challenges to modern cancer research. P-CARE will strengthen the collaboration between Italian and Austrian research institutes in the areas of genetics, biotechnology and the cancer clinics and generate a technical platform to investigate mechanism of therapy resistance formation, aiming to increase the efficacy of therapeutic treatments.
The project will develop a shared platform for the identification of drugs capable to re-sensitize resistant tumors to conventional oncologic treatments by the repositioning of drugs already approved for the treatment of other pathologies. Further, P-CARE will implement strategies of precision medicine aiming to overcome resistance to anti-cancer immunotherapy by reproducing the immune response of the tumormicorenviroment in vitro. P-CARE will build an efficient trans-border network for sharing technology and knowledge that will be made accessible for academic and clinical cancer research in and outside the Programme area.
Flow control techniques enabling increased pressure ratios in aero engine core compressors for ultra-high propulsive efficiency engine architectures

The ultra-high propulsive efficiency demonstrator engine developed by Safran Aircraft Engines and GE Germany (GEDE) within Clean Sky 2 promises a considerable reduction of pollutant and noise emissions as well as aero engine fuel burn. While the geared architecture allows a further increase in bypass ratio and thus propulsive efficiency, a core engine with increased pressure ratio maximizes the turbofan´s thermal efficiency and performance. However, the increased pressure ratio within the HPC demands a reduction of the flow cross section, which results in larger relative clearances and endwall boundary flows that penalize the compressor efficiency and operability.
The objectives of the proposed project are, first, to develop an innovative HPC rear stage concept that addresses the challenging aerodynamics associated with increased rotor clearances by combining the casing treatment technology with complimentary flow control techniques to strengthen the flow across the entire span, second, to provide a high-speed, large-scale multi-stage compressor test facility and execute an engine-representative rig test to validate the rear stage concepts collaboratively developed by GEDE and the Technische Universität München (TUM), third, to apply advanced data acquisition techniques that provide a detailed compressor performance and operability assessment as well as a thorough understanding of the unsteady flow physics and aerodynamic loss mechanisms.
TUM´s years of experience in aerodynamic blade design and the development of flow treatment technologies in conjunction with its high-speed compressor test facility that is particularly suited for the validation of compressor rear stage concepts as well as the institute´s proven capability to successfully execute rig tests on an industrial standard will greatly benefit GEDE´s research efforts and ensure a technology maturation to TRL5, thus, allowing for a subsequent technology validation in a ground test demonstrator.
Vorrichtung zum Erkennen von Fremdteilen aus Kunststoff, insbesondere Polypropylenbändchen, -gewebe und -folien in oder zwischen Faserflocken.

Eine Vorrichtung zum Erkennen von Fremdteilen aus Kunststoff, insbesondere Polypropylenbändchen, -gewebe und -folien in oder zwischen Faserflocken, z.B. aus Baumwolle, in der Spinnereivorbereitung, umfasst Beleuchtungseinheiten (7, 8, 9, 11, 13) zur Beleuchtung der Faserflocken (4) und der Fremdteile (5) zum einen mit unpolarisiertem Licht aus einem Wellenlängenbereich und gleichzeitig mit polarisiertem Licht aus einem anderen Wellenlängenbereich. Die Beleuchtungseinheiten (7, 8, 9, 11, 13, 25) sind so ausgebildet und angeordnet, dass das unpolarisierte Licht und das polarisierte Licht an Inspektionsstellen (2, 12) die Faserflocken (4) und die Fremdteile (5) zu beleuchten vermag. Die Vorrichtung umfasst zudem mindestens eine Kamera (6, 15, 16) zur Detektion des von den zwei Inspektionsstellen (2, 12) kommenden unpolarisierten und polarisierten Lichts. Die Inspektionsstellen (2, 12) können derart nahe beieinanderliegen, ohne dass eine gegenseitige Beeinflussung der beiden Lichtarten stattfindet.
Best invariant and minimax estimation of quantiles in finite populations

The theoretical literature on quantile and distribution function estimation in infinite populations is very rich, and invariance plays an important role in these studies. This is not the case for the commonly occurring problem of estimation of quantiles in finite populations. The latter is more complicated and interesting because an optimal strategy consists not only of an estimator, but also of a sampling design, and the estimator may depend on the design and on the labels of sampled individuals, whereas in iid sampling, design issues and labels do not exist.We study estimation of finite population quantiles, with emphasis on estimators that are invariant under the group of monotone transformations of the data, and suitable invariant loss functions. Invariance under the finite group of permutation of the sample is also considered. We discuss nonrandomized and randomized estimators, best invariant and minimax estimators, and sampling strategies relative to different classes. Invariant loss functions and estimators in finite population sampling have a nonparametric flavor, and various natural combinatorial questions and tools arise as a result.
CLEANING COMPOSITIONS CONTAINING DISPERSINS II

The present invention relates to specific cleaning compositions comprising polypeptides having hexosaminidase activity. The invention further relates to the use of said compositions as well as methods of using said compositions.
Modelagem Farmácias Vivas-Jardins terapêuticos para implantação em Serviços de Atenção Primária à Saúde no SUS

O objetivo da Modelagem Farmácias Vivas-Jardins Terapêuticos para Implantação em Serviços de Atenção Primária à Saúde no SUS é fornecer um passo-a-passo, com linguagem clara e direta, para aqueles que tenham interesse em implantar e implementar o uso de plantas medicinais em serviços de Atenção Primária à Saúde (APS). A Modelagem está dividida em 6 módulos: 1) História da Regulamentação das Plantas Medicinais, Fitoterápicos e Farmácias Vivas no Brasil; 2) Etapas para implantação de uma Farmácia Viva-Jardim Terapêutico; 3) Benefícios da Farmácia Viva-Jardim Terapêutico nos serviços de Atenção Primária à Saúde; 4) Desafios para implantação e manutenção da Farmácia Viva-Jardim Terapêutico; 5) Estratégias de fortalecimento da Farmácia Viva-Jardim Terapêutico nos serviços de saúde e no município; 6) Formação de Rede de Cuidado nos Territórios. É uma grande alegria poder contribuir com a disseminação do uso das plantas medicinais, por meio desta Modelagem. É certo que se entrarmos em um serviço de saúde e nele sentirmos os cheiros das plantas medicinais poderemos resgatar histórias e construir novas narrativas sobre o processo de saúde-doença-cuidado, promovendo uma melhor compreensão das formas de produzir e manejar a saúde com a beleza e riqueza das plantas medicinais.
Reconstructing human cortex development and malformation with single-cell transcriptomics

Technologies to sequence single-cell transcriptomes (scRNA-seq) are revolutionizing our ability to analyze cell composition and differentiation in complex tissues. In parallel, recent innovations allow the generation of three-dimensional tissues from stem cells that recapitulate human development. In this proposal, we will focus on human cortex development modelled by cerebral organoids. Our vision is to create an integrative single-cell transcriptomic platform to reconstruct cerebral organoid development, and dissect network alterations that lead to human brain malformations. Our project will be advanced through the following objectives: 

1. Single-cell transcriptome-coupled lineage tracing: We will use cellular barcoding to label individual cortical progenitor cells, trace their output and lineage trees with high-throughput scRNA-seq, and quantify lineage transition probabilities between cell types.

2. Gene knockout screens in mosaic organoids: We will use CRISPR/Cas9 to perform genetic screens of up to 100 genotypes in mosaic organoids to understand mechanisms that regulate cell lineage decisions during cortex development. 

3. High-throughput reconstructions of cortex malformations: We will generate cerebral organoids from patients with cortical malformations and reconstruct networks and infer differentiation hierarchies using high-throughput and lineage-coupled scRNA-seq. We will spatially resolve network aberrations using sequential fluorescence in situ hybridization (seqFISH).

ORGANOMICS provides an entirely new quantitative direction to study human corticogenesis. We will build high-resolution models of cortex development by measuring the expression and function of genes in thousands of single cells. Our interdisciplinary project will lead to groundbreaking insight into mechanisms underlying neurodevelopmental diseases. Our general strategy can be extended to various other organ systems where protocols to generate in vitro counterparts can be established.
Exchange of experiences in monitoring mechanisms, indicators and methodologies addressed to improvement in the delivery of policies and instruments in the framework of Regional RIS3 across Regions.

Regional Smart Specialisation Strategies (S3) developed during last years, as ex-ante conditionality for implementing Structural Funds, are facing a CHALLENGE on MONITORING: how to adopt one STRUCTURED AND EVIDENCE DATABASED APPROACH leading to the definition of a set of indicators for MONITORING / EVALUATING S3? and how to select indicators using METHODOLOGICAL CRITERIA? 
Current EU and national initiatives are addressed to exchange S3 implementation, e.g. IPTS through S3 platform, or FECYT i.e. in Spain, but the “MONITORING CHALLENGE” has NOT BEEN SOLVED yet. 
MONITORIS3 is INNOVATIVE because will address this challenge SYSTEMATICALLY by the first time in Europe with a cross-border approach. Thus, the project´s MAIN GOAL is to facilitate the IMPROVEMENT OF S3 RELATED STRUCTURAL FUNDS POLICIES DELIVERY (6 POLICY INSTRUMENTS) through promotion of exchange of experiences and policy learning on MONITORING STRATEGIES OF SUCH INSTRUMENTS among a consortium of regionally relevant actors on S3. MONITORIS3 is supported by the following specific ACTIVITIES and OUTPUTS: 
- ONE INTERREGIONAL MAPPING OF S3 MONITORING STRATEGIES AT INTERREGIONAL LEVEL (on 6 preselected POLICY INSTRUMENTS): Regional (partners) “Stay of play” analysis at the beginning of the project.
- INTERREGIONAL POLICY LEARNING PROCESS through 8 INTERREGIONAL THEMATIC SEMINARS around 4 WORKING GROUPS to organize the 9 policy instruments addressed, with active involvement of regional STAKEHOLDERS GROUPS. 
- BEST PRACTICES (BBPP) SELECTION and PEER-TO-PEER process (7 STUDY VISITS) to ensure the best introduction of selected BBPP by each region and thus facilitate the exchange. 
- 6 REGIONAL ACTION PLANS ON S3 MONITORING elaborated on the basis of selected practices to be transferred to each region around the 9 policy instruments selected. 
To achieve these objectives, MONITORIS3 gathers 6 partners from 6 EU Regions and 1 advisory partner with competences on implementing and/or monitoring S3.
360 DEGREE PRIVACY FILM

Light control films are provided that confine light transmitted therethrough to be within a 360° view region and block light outside of this view region. The light control films can provide security in all directions including right-and-left and up-and-down of the films, without compromising light transmittance compared to one-dimensional light control films. The light control films include an array of light transmissive, tapered posts and absorptive regions disposed between the posts.
Intensity mapping of the atomic carbon cii line: the promise of a new observational probe of dusty star-formation in post-reionization and reionization epoch

I propose for funding to construct a spectrometer to map in 3-D the intensity due to line emission, a
technique known as Intensity Mapping. Instead of detecting individual galaxies, this emerging technique
measures signal fluctuations produced by the combined emission of the galaxy population on large regions
of the sky in a wide frequency (i.e. redshift) band, and thus increases sensitivity to faint sources.
Capitalizing on a recent technology breakthrough, our intensity mapping experiment will measure the 3-D
fluctuations of the [CII] line at redshifts 4.5<z<8.5. [CII] is one of the most valuable star formation tracers
at high redshift. My project will answer the outstanding questions of whether dusty star-formation
contributes to early galaxy evolution, and whether dusty galaxies play an important role in shaping cosmic
reionization.
My team will first build, test, and finally install the instrument on the APEX antenna following an
agreement with APEX partners. The spectrometer will be based on the state-of-the-art development of new
arrays in the millimeter using Kinetic Inductance Detectors. Spectra (200-360 GHz) will be obtained by a
fast Martin-Puplett interferometer. Then, we will observe with CONCERTO a few square degrees and offer
a straight forward alternative for probing star formation and dust build-up in the early Universe. Finally,
CONCERTO will set to music the various cosmic evolution probes. Cross-correlation of the signals will be
used in particular to capture the topology of the end of reionization era.
CONCERTO will be one of two instruments in the world to perform intensity mapping of the [CII] line in
the short term. The novel methodology is extremely promising as it targets an unexplored observable
touching on some of the fundamental processes building the early universe. In the flourishing of new ideas
in the intensity-mapping field, CONCERTO lies at the forefront.
Brettonwoodský mezinárodní měnový systém: Příčiny a dopad zániku

This thesis concerns with the identification of underlying causes of the Bretton Woods international monetary system formation and dissolution. The twentieth century proved to be the most disruptive era in the history of financial markets. After the events of the World War II, a viable framework for the facilitation of international trade was a major priority. The Bretton Woods conference of 1944 established this framework and marked the future of economic development. After more than 20 years of operation, the Bretton Woods sys-tem was dissolved following the events of the 1971 Nixon Shock. This work addresses the events preceding the formation of Bretton Woods, the subsequent operations of the IMF and the key causes of the Bretton Woods demise.