SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Homologous recombination and its application in manipulating animal mitochondrial dna

Mitochondrial DNA (mtDNA) is a multi-copy genome that works with the nuclear genome to control energy production and various cellular processes. To date, disorders associated with mutations in mtDNA are among the most common genetically inherited metabolic diseases1. However, our knowledge regarding many aspects of mtDNA biology remains limited, and we know even less about how it influences development and organismal traits. This is largely due to our inability to manipulate mtDNA. Recently, a colleague and I developed novel genetic tools in Drosophila that allowed us to isolate animal mitochondrial mutants for the first time, and to create heteroplasmic organisms containing two mitochondrial genotypes2,3. These advances make Drosophila a powerful system for mtDNA studies. Importantly, I showed that Drosophila mtDNA could undergo homologous recombination. Furthermore, I established a system to induce recombination at specific sites and select for progeny containing only the recombinant genome4. Thus, my work has demonstrated the existence of recombination in animal mitochondria, and opens up the possibility of developing a recombination system for functional mapping and manipulating animal mtDNA. Here I propose to 1) identify components of the mitochondrial recombination machinery by a candidate RNAi screen; 2) develop a recombination toolkit to map trait-associated mtDNA sequences/SNPs; and 3) build a site-directed mutagenesis system by establishing robust ways to deliver DNA into fly mitochondria. Given the essential functions of mitochondria and their involvement in incurable diseases, the genetic tools developed in this proposal will transform the field by making it possible to link mtDNA variations to phenotypic differences and introduce specific mutations into mtDNA for functional studies at organismal level. These advances will open many possibilities to accelerate our understanding on how mtDNA impacts health, disease and evolution.
MinXSS-2 CubeSat mission overview: Improvements from the successful MinXSS-1 mission

The second Miniature X-ray Solar Spectrometer (MinXSS-2) CubeSat, which begins its flight in late 2018, builds on the success of MinXSS-1, which flew from 2016-05-16 to 2017-05-06. The science instrument is more advanced -- now capable of greater dynamic range with higher energy resolution. More data will be captured on the ground than was possible with MinXSS-1 thanks to a sun-synchronous, polar orbit and technical improvements to both the spacecraft and the ground network. Additionally, a new open-source beacon decoder for amateur radio operators is available that can automatically forward any captured MinXSS data to the operations and science team. While MinXSS-1 was only able to downlink about 1 MB of data per day corresponding to a data capture rate of about 1%, MinXSS-2 will increase that by at least a factor of 6. This increase of data capture rate in combination with the mission's longer orbital lifetime will be used to address new science questions focused on how coronal soft X-rays vary over solar cycle timescales and what impact those variations have on the earth's upper atmosphere.
Reference frames in visual selection

We review neuropsychological evidence for visual selection operating in different reference frames. There is general agreement that there may be a separation of coding space near to and farther from the body, and that deficits in selecting stimuli within each form of spatial representation may be impaired in patients with unilateral neglect. However, there remains a lack of consensus about whether all forms of spatial representation relate to the body or whether there are spatial representations based on reference frames abstracted from the body (allocentric and object-centered spatial codes). Here we will review the evidence for spatial coding in these more abstracted reference frames (allocentric and object-centered but also environmental) and argue for the psychological reality of (at least) allocentric spatial coding. We discuss computational accounts of how such codes may be created as objects are selected.
Antonio Trampus (ed.), Ã¢â‚¬Å“Venezia dopo VeneziaÃ¢â‚¬Â

portuale e lo spazio urbano dal punto di vista […] sociale, urbanistico, istituzionale e culturale, tale da realizzare un'effettiva integrazione tra città e porto e tra i rispettivi attori, capaci di attivare specifiche strategie di trasferimento e produzione delle conoscenze, nuove dinamiche nella gestione della comunicazione e dell'informazione, nuove esperienze di cittadinanza e di governo dello spazio urbano» ( 14).Venezia dopo Venezia non si limita però a studiare le città adriatiche come esemplari "città-porto", ma i porti franchi quali caso particolare, caratterizzati da un ulteriore e più avanzato livello di sperimentazione.
Plan de negocio para la creación de una empresa distribuidora y comercializadora de prendas de vestir de arte urbano en el sector de Quito

ABSTRACT 
The development of the textile activity in Ecuador has generated great economic income, generating sources of employment in Ecuadorians. With the number of indirect jobs chaining 33 productive branches in the country. This project aims to develop a business in order to create a Distributor and Marketing Company of Urban Art clothing in the southern sector of Quito. For the development of the business plan, it began with a theoretical conceptual foundation of the textile sector in Ecuador, Hip Hop culture and clothing. Regarding the methodological framework, it is a descriptive research and a quantitative approach, using research instruments such as the survey and documentary review to demonstrate the existence of the problem posed. From which the proposal is made, which is a model of market studies, organization, location, legal and financial studies, verifying its feasibility. Finally, the conclusions that refer to the generation of the project and recommendations to its implementation are made. Key words: Business Plan / Textile Activity / Urban Art / Hip Hop
An Ontology for Musical Performances Analysis: Application to a Collaborative Platform Dedicated to Instrumental Practice

Performance analysis is a common issue in the musical field, especially for instrument teachers and musicologists. That is why we present in this paper an ontology (technical aspect) and a descriptive model (pragmatic aspect) to allow music teachers and students to create semantic annotation on musical performances. As such, we start by studying recorded piano lessons and analyze the required concepts and roles. We then propose a general performance description model based on these lessons and detail how musicology rules can be used to automatically infer new information on a given piece. Lastly, we discuss the integration of our work to an e-learning web-based collaborative platform for musical education.
Understanding of Phytoplankton Community Dynamics Through Algae Bioassay Experiment During Winter Season of Jinhae bay, Korea

The distributions of phytoplankton assemblages and environmental factors in Jinhae Bay and their relationships were investigated to estimate the potential limiting nutrient for phytoplankton growth and community structure. In situ algal bioassay experiments were also conducted to assess the species-specific characteristics in phytoplankton responses under different nutrient conditions (control, N(+) and P(+) treatment). During the study periods, bacillariophyceae and cryptophyceae occupied more than 90% of total phytoplankton assemblages. Phytoplankton standing crops in the inner part of Masan Bay were higher than that of Jinhae Bay. The DIN:DIP ratio, pH and transparency showed the significant positive correlation with phytoplankton biomass. According to cluster and multidimensiolnal scaling (MDS) analysis based on phytoplankton community data from each station, the bay was divided into three groups. The first group included stations from the south-western part of Jinhae bay where cryptophyta species were dominated. The second group was distinguished from inner stations in Masan Bay. These stations showed low transpancy and high DIN:DIP ratio. The other cluster included the stations from the eastern part and central part of Jinhae Bay, which was characterized by the high DSi:DIP ratio and dominant of diatom species. Phosphorous (P) was limited in Masan Bay due to significantly increases in the phytoplankton abundances. Based on stoichiometric limitation and algal bio-assay in Jinhae Bay, nitrogen (N) was a major limiting factor for phytoplankton production. However, silicate (Si) was not considered as limiting factor, since Si/DIN and Si/P ratio and absolute concentration of nutrient did not create any potential stoichiometric limitation in the bay. This implies that high Si availability in winter season contributes favorably to the maintenances of diatom species.
Potencial dendroenergético de dos clones de Eucalyptus sp. en Corrientes, Argentina

Las plantaciones forestales con fines energéticos tienen como objetivo la obtención de grandes cantidades de biomasa mediante rotaciones de corta duración. El objetivo de este trabajo fue determinar el potencial dendroenergético de dos clones de Eucalyptus sp. creciendo en las lomas y planicies arenosas de Corrientes, Argentina. Se analizaron las relaciones entre productividad de biomasas y variables silvícolas, climáticas y ambientales. La sobrevivencia y la productividad en volumen fue alta. Se registraron diferencias significativas entre clones para la producción de biomasa en función de sus compartimentos y edad. A los 24 meses la producción de biomasa de fuste para un esquema de manejo de 3333 ha-1 árboles fue de 32,2 Mg ha-1 y 38,5 Mg ha-1 del clon puro e híbrido, respectivamente. En un contexto de falta de limitaciones, desde el punto de vista climático y condiciones de sitio, es posible asociar la productividad anual de biomasa a la densidad de plantación. En suelos poco fértiles, ambos clones registraron alta productividad en altas densidades de plantación. El impulso a la generación de energías renovables a partir de la biomasa forestal es una oportunidad para Corrientes, ya que cuenta con el recurso y las condiciones climáticas favorables, aunque es necesario continuar estudiando el desarrollo de estos sistemas en ambientes frágiles, identificando las prácticas de manejo que disminuyan su impacto y favorezcan un manejo sustentable.
Prosociallearn - gamification of prosocial learning for increased youth inclusion and academic achievement

ProsocialLearn will establish a new market for digital games aiming at increasing social inclusion and academic performance. A ground-breaking digital gaming genre will be created that focuses on helping children to acquire prosocial skills necessary for positive relationships, team working, trustworthiness and emotional intelligence. ProsocialLearn will deliver a series of disruptive innovations building on a game development and distribution platform for the production of prosocial games that engages children and stimulates technology transfer from traditional game industry to the education sector. ProsocialLearn will offer games developers scientifically proven prosocial game elements for development digital games. An application programming interface (API), ProsocialAPI, will allow developers to integrate functions into games including visual sensing, identification of prosocial signals from in-game actions, personalised adaptation of game elements, player profiles, game mechanics and expressive virtual characters, and support for data collection with protection of personal data. SMEs from the traditional game industry will work together with serious games companies to produce a series of exciting digital games targeting European schools. Through a multi-disciplinary collaboration between industry, researchers, psychologists, pedagogists and teaching professionals, ProsocialLearn will address complex factors associated with child development and advanced ICT in school curricula. Two SMEs within the consortium will produce an initial set of games and additional SMEs will be incorporated in the third year of the project to foster market creation. Both short term and longitudinal studies (pilots) will be conducted at schools across Europe to build scientific evidence of the benefits of prosocial gaming in different cultural settings and scales, and to explore business models, business plans and verify financial viability of the ProsocialLearn platform.
Visegrad initiative for nuclear cooperation

After a common expression of willingness to cooperate and legal establishment of V4G4 Centre of Excellence Association, VINCO project represents the next stage of capacity building in nuclear technologies in Central European countries. Participating countries defined already their specializations: helium technology in Czech Republic, design and safety analyses in Slovakia, fuel studies in Hungary and material research in Poland. Having such expertise, the joint development of Gen IV nuclear technologies with the special emphasis on gas-cooled reactors is fully possible. Thus, the main objectives of the regional VINCO project are: (i) development of the principles of cooperation and rules of access to existing and planned infrastructure, (ii) identification of the specific objectives of the R & D activities in the cooperating countries, (iii) description and analysis of the existing research, training and educational equipment and capabilities, (iv) determination of the investment priorities in cooperating countries and (v) setting up of joint research, educational and training projects. It is expected that the joint activities will result in coordination of actions allowing to obtain financing from the Structural Funds available for the Visegrad countries. These funds would allow for a huge increase of mass and modernization of the research potential in the region. Close cooperation with other EU institutions (mainly CEA, France) will ensure better description of the investments needed in Visegrad Region, tightening of pan-European cooperation and strengthening of the role of V4 countries, helping them to evolve from users to the suppliers of R&D capabilities in nuclear technologies. A major expected impact of the project would be setting up of a distributed regional research centre specialized in nuclear technologies needed to develop Gen IV reactors and to improve safe operation of existing and planned Nuclear Power Plants in the region.
Soil Penetration by Earthworms and Plant Roots—Mechanical Energetics of Bioturbation of Compacted Soils

We quantify mechanical processes common to soil penetration by earthworms and growing plant roots, including the energetic requirements for soil plastic displacement. The basic mechanical model considers cavity expansion into a plastic wet soil involving wedging by root tips or earthworms via cone-like penetration followed by cavity expansion due to pressurized earthworm hydroskeleton or root radial growth. The mechanical stresses and resulting soil strains determine the mechanical energy required for bioturbation under different soil hydro-mechanical conditions for a realistic range of root/earthworm geometries. Modeling results suggest that higher soil water content and reduced clay content reduce the strain energy required for soil penetration. The critical earthworm or root pressure increases with increased diameter of root or earthworm, however, results are insensitive to the cone apex (shape of the tip). The invested mechanical energy per unit length increase with increasing earthworm and plant root diameters, whereas mechanical energy per unit of displaced soil volume decreases with larger diameters. The study provides a quantitative framework for estimating energy requirements for soil penetration work done by earthworms and plant roots, and delineates intrinsic and external mechanical limits for bioturbation processes. Estimated energy requirements for earthworm biopore networks are linked to consumption of soil organic matter and suggest that earthworm populations are likely to consume a significant fraction of ecosystem net primary production to sustain their subterranean activities.
Development of the Cybersecurity System of Internet Services as a tool to improve the security of use of Internet services by end-users.

Reference number of the aid programme: SA.41471(2015/X) Purpose of public aid: Article 25 of EC Regulation No 651/2014 of 17 June 2014 declaring certain types of aid compatible with the internal market in the application of Articles 107 and 108 of the Treaty (OJ L. I'm sorry. EU L 187/1 of 26.06.2014). The aim of the project is to carry out R & D work on the development of the Cybersecurity System of Internet Services (SCSI), which significantly improves the security of end-users of Internet services. The technology is at the second level of technological readiness – the desired functionalities of the system and their application have been defined, taking as a starting point the protection of the user interface (UIP). Ultimately, we will create a prototype of the system and validate it in real warunaks by integration with the website of the partner, which will allow to obtain the IX level of readiness. In 2017, Gartner included the trend related to protection against attacks against users, including Gartner, pointing to a niche in the development of cybersecurity, i.e. User Interface Protection (UIP). This is linked to the pursuit of a layer in Internet services to protect against specific attacks of business logic. The competition analysis confirms the lack of efficient and effective solutions based on this concept. Effective protection of end-users’ data is crucial in the light of legal changes. IT’S A GDPR. The result of the project will be a product innovation. It will be a solution to protect users from man-in-the-Browser (MitB) and Man-in-the-Middle (MITM) attack vectors to respond to demand, in particular among: banks, online lending companies, hosting companies and VOD networks. It will be distinguished by its approach to protection against cyber attacks on websites aimed at unauthorised change of displayed content on the user’s side or theft of data.
Cancer treatment during pregnancy: from fetal safety to maternal efficacy

The evolution in drug regulation of the last 50 years has left pregnant women and their fetuses orphaned. This is particularly problematic for cancer during pregnancy, which raises a difficult and conflicting medical ethical decision process and which has recently become increasingly frequent. In 2012 we published the first prospective study indicating that antenatal exposure to cancer treatment can overall be considered safe. Building on this proof of concept, the current proposal wants to take a groundbreaking step towards developing a standard of care for cancer during pregnancy by addressing –in an integrated fashion- the challenges at the level of the fetus, the mother and the fetomaternal barrier. At the core of this proposal lies an international registry of pregnant women with cancer, along with a registry of their children, and biobanks of maternal, placental, cord blood and tumoral tissues. Research track ‘child’ aims to deliver robust evidence of fetal safety. Research track ‘mother’ aims to address the emerging concerns in the oncological management of the mother, and specifically, the possible distinct biology of pregnancy-associated breast cancer, the most frequent cancer type in pregnancy. The research approach includes large-scale clinical follow-up studies along with laboratory studies on patient biomaterials, including pharmacological investigations and RNA-sequencing studies. Complementary to these studies is research track ‘placenta’ in which cutting-edge models of human placental research are used to address the poorly understood physiological basis of the placental barrier function in this specific situation. This ambitious program will rely on a multidisciplinary team of experts. Not only may the scientific deliverables of this proposal constitute a major step forward to the well-being of both mother and fetus in a pregnancy complicated by cancer, the methodological approach may also provide critical impetus to further research in this field.
A Gaze on Rural Education According to Scientific Discourses during the Last Decade

Abstract The largest proportion of illiteracy and lack of access to education in the world is concentrated in rural areas; therefore it is important to ensure there is access to quality education in these spots. This challenge is assumed by different branches of social research and it is reflected within the publication of articles in scientific journals. In the present document the scientific discourse surrounding the theme of rural education during the last decade was analyzed. To do this, the paper focuses on three aspects: the countries that set the agenda, the geographical areas that represent most of the attention and the prevalent themes within continents. It was observed that USA was the most productive country in terms of scientific writings with 30%; that Asia is really interested in health issues associated to rural education; that in Europe gender issues are on the table and that the African and Asian continents, as well as Latin America, are interested only on their own issues, as 100% of the times they only wrote about themselves.
OUT-OF-HOME ADVERTISING INVENTORY RATINGS METHODS AND SYSTEMS

Methods, systems and programs for estimating exposure to outdoor advertising are provided. In certain embodiments, exposure data is produced based on respondent data and traffic data. In certain embodiments, exposure data is produced based on outdoor inventory data and traffic data.
Future Factory – Flexible, optimised and traceable production systems

Design, implementation and evaluation of new integrated computer technologies and architectures that will enable the implementation of a flexible, energy-saving production system for small and medium-sized enterprises. Emphasis will be placed on aspects such as intuitive user interface, production flexibility, easy reconfigurability, energy efficiency, cloud architecture SW applications, data transparency across the system and intelligent, software-intensive mechatronic components.
The effects of nasal continuous positive airway pressure on vascular functions and serum cardiovascular risk factors in obstructive sleep apnea syndrome

We investigated whether the nasal continuous positive airway pressure (nCPAP) could have impacts on impaired vascular functions and serum cardiovascular risk factors in obstructive sleep apnea syndrome (OSAS).We enrolled 25 OSAS patients of moderate to severe degree. After polysomnography, carotid-femoral pulse wave velocity (cfPWV) and flow-mediated dilation (FMD) were measured. Also, serum levels of C-reactive protein (CRP), total cholesterol, triglyceride, high-density lipoprotein (HDL) cholesterol, glucose, and insulin were measured. After nCPAP treatment (mean duration, 138.7 ± 42.6 days), these tests were performed again.The mean apnea hypopnea index prior to nCPAP was 64.9 ± 20.0/h, which decreased to 4.1 ± 2.0/h with nCPAP (p < 0.001). After nCPAP, cfPWV (m/s) decreased from 11.2 ± 4.5 to 9.3 ± 2.1 (p = 0.031), and FMD (%) was improved from 5.52 ± 2.49 to 6.58 ± 2.50 (p = 0.006). Body mass index, serum levels of CRP, total cholesterol, triglyceride, HDL cholesterol, or glucose did not change after nCPAP. Insulin resistance was not improved either.The cfPWV and FMD were significantly improved after nCPAP treatment, even though there was no significant change in body weight or serum cardiovascular risk factors. The nCPAP treatment could decrease risks of cardiovascular complications in OSAS patients through improving vascular functions.