SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Spatial nanoscale control of growth and adhesion factors to enhance the osteogenic differentiation of mesenchymal stem cells

In OsteoNano project the training-through-research is targeted at the developing of biomimetic surfaces to study and control the osteogenic differentiation of human Mesenchymal Stem Cells (hMSCs). Osteogenic differentiation of hMSCs can be guided by growth factors, such as bone morphogenetic protein 2 (BMP-2). Currently, recombinantly expressed BMP-2 is applied clinically to enhance the healing of fractured sites. However, the absence of a control over the growth factor surface density and adhesion of cells induce side effects such as ectopic bone formation. The first aim of this project is to present BMP-2 to hMSCs in a spatially controlled manner by applying surface sensitive and high-resolution techniques. The growth factors will be linked to the surface using glycosamminoglycans (GAGs) such as heparan sulphate (HS), and combined with adhesives molecules such as cyclic RGD sequences, which are known to increase the osteogenic effects of BMP-2 by activation of Integrin alphaV-beta3 and alpha5beta1. Our approach will be to design biomimetic surfaces with stepwise increasing complexity, by binding each component in a controlled manner, in terms of orientation, surface density and spatial arrangement. By using these functionalized substrates for hMSCs osteogenic differentiation we will answer several fundamental questions regarding the role of BMP-2 and its interaction with HS and RGD sequences on the osteogenic commitment of hMSCs. 
The biomimetic surfaces proposed here, present several fundamental studies, advantages and breakthroughs (i) reduced use of BMP-2 bound on the surface: indeed (i) the binding prevents the cellular internalization of the growth factors; (ii) possibility to enhance the osteogenic differentiation by surface co-presentation of BMPs or/and of RGDs; (iii) surface versatility with respect to stiffness which could positively impact osteogenic differentiation.
Optical waveguide termination device, method of forming the same and system for measuring efficiency of the same

The present disclosure relates to optical waveguide termination devices. In some embodiments, an optical waveguide termination device is coupled to an end of an optical waveguide. The optical waveguide termination device is a tapered structure. In various embodiments, an optical absorption rate of the tapered structure is increased to enhance a termination efficiency. The optical absorption is increased by highly-doped material, multi-layer structure, different cladding, and periodic structure. The enhancement of the termination efficiency benefits size reduction of the tapered structure.
Desarrollo de tecnología innovadora para laminación de varillas cilíndricas a partir de cabezas de rieles desguazados

Number_reference_aid_programa: SA.42799(2015/X), aid_de_minimis: §42 del Reglamento del Ministro de Infraestructuras y Desarrollo, de 10 de julio de 2015, relativo a la concesión de ayuda financiera por parte de la Agencia Polaca para el Desarrollo Empresarial en el marco del Programa Operativo de Crecimiento Inteligente 2014-2020. Proyecto: concepto de tecnología innovadora de laminación de varillas cilíndricas de las cabezas de carriles desguazados (en grados seleccionados);2. Calibración de rodillos (para especies individuales) y selección de parámetros tecnológicos del proceso de laminación longitudinal; 3.Hacer una simulación numérica de los procesos de laminación longitudinal diseñados para producir varillas cilíndricas a partir de las cabezas de los carriles desguazados;4.Hacer ensayos de rodadura en las condiciones de producción del solicitante. El contratista asume la participación de los usuarios finales en el proceso de desarrollo tecnológico participando en el proceso de prueba y revisión de la tecnología. El resultado del proyecto será una tecnología innovadora de rodaduras cilíndricas de las cabezas de carriles desguazados, constituyéndose en una innovación de procesos a escala del mercado polaco. El innovador producto será varillas cilíndricas laminadas que permitan obtener una carga de rieles desguazados para la producción de bolas, lo que permitirá reducir los costos de producción del solicitante, y obtener un nuevo producto, que es una varilla cilíndrica.
A case-cohort study examining lifetime exposure to inorganic arsenic in drinking water and diabetes mellitus

Consumption of drinking water with high levels of inorganic arsenic (over 500 μg/L) has been associated with type II diabetes mellitus (DM), but previous studies have been inconclusive about risks at lower levels (<100 μg/L). We present a case-cohort study based on individual estimates of lifetime arsenic exposure to examine the relationship between chronic low-level arsenic exposure and risk of DM.This case-cohort study included 141 cases of DM diagnosed between 1984 and 1998 as part of the prospective San Luis Valley Diabetes Study. A comparison sub-cohort of 488 participants was randomly sampled from 936 eligible participants who were disease free at baseline. Individual lifetime arsenic exposure estimates were determined using a methodology that incorporates the use of a structured interview to determine lifetime residence and employment history, geospatial modeling of arsenic concentrations in drinking water, and urine arsenic concentrations. A Cox proportional hazards model with known DM risk factors as time-dependent covariates was used to assess the association between lifetime exposure to inorganic arsenic in drinking water and incident DM.Our findings show a significant association between inorganic arsenic exposure and DM risk (hazard ratio [HR]=1.27, 95%=1.01, 1.59 per 15 μg/L) while adjusting for ethnicity and time varying covariates age, body mass index and physical activity level.Exposure to low-level inorganic arsenic in drinking water is associated with increased risk for type II DM in this population based on a comprehensive lifetime exposure assessment.
MECHANISM TO REDUCE MISSING BREACH DETECTION IN GEOFENCING SOLUTION

A system and method for a mobile device to efficiently use a geofence capability without draining its battery, and to allow flexibility in specifying various parameters related to geofencing, such as the latency and confidence in determining when or where a geofence breach occurs, and reducing the probability of not detecting a geofence breach.
METHOD OF CONTROLLING CONTINUOUSLY VARIABLE AUTOMOTIVE TRANSMISSION

The transmission ratio of an automotive continuously variable transmission is controlled on the basis of the difference between a target rotational speed of the engine which is preset according to an indication of the driver's intention of acceler-a-tion or deleration and a detected rotational speed of the engine. The gain of the rate of change of the transmission ratio is reduced as the detected rotational speed of the engine becomes higher, and the gain of the rate of change of the transmission ratio is increased as the detected rotational speed of the engine becomes lower. Alternatively, the gain of the rate of change of the transmission ratio is of a relatively small value when the detected rotational speed of the engine is equal to or higher than a preset speed, and the gain of the rate of change of the transmission ratio is of a relatively large value when the detected rotational speed of the engine is lower than said preset speed.
Development of soft, efficient, powerful, and rapid artificial muscles for the design of a soft wearable haptic exoskeleton

Soft robotics is a growing research field promising to apply automation to new areas of our societies such as medicine, agriculture and exploration. However, since soft robotics is a relatively recent research field, many fundamental components of soft robots still demonstrate disappointing capabilities. Indeed, actuation is one of the most vital requirement of robots but it is yet to be solved adequately. 
This proposal describes the development and characterization of a new soft actuator. We call these innovative soft actuator “M-SCPAs”, as they are inspired by recent advances in Magnetoactive polymeric fiber (MAEs) and  Supercoiled Polymer Actuators (SCPAs). M-SCPAs will be manufacThis proposal aims at creating a new type of soft actuator. Soft actuators are a key component of the soft robotics research field, with applications in medical, agricultural or wearable technologies. We propose to use “M-SCPAs”, named after the 2 key distinct concepts used in their design.
-The first key concept is the use of a magnetoactive (M-) polymeric fiber. Inspired by recent advances in magnetoactive materials, we propose to embed strongly magnetized ferromagnetic particles within an extruded polymer fiber. When exposed to a magnetic field, the particles will internally pivot, and the fiber contract. 
-The second key concept is the use of an helical structure similar to the one used by “Supercoiled Polymer Actuators” (SCPAs). The twisting of a polymeric fiber creates a three-dimensional structure akin to a typical steel spring. From this structure is derived inherent softness, convenient form factor, as well as increased contractile capabilities. 
The proposal details the combination of these two ideas to create a new type of actuator overcoming each of the respective original actuators limitations. The proposal also proposes the demonstration of these actuators through the manufacture of a soft wearable haptic device powered and its subsequent use in an haptic feedback study.
Folksonomy Query Suggestion via Users’ Search Intent Prediction

AbstractRecently, social bookmarking systems have received surging an increasing attention in both academic and industrial communities. The main thrust of these Web 2.0 systems is their easy use that relies on simple intuitive process, allowing their users to label diverse resources with freely chosen keywords aka tags. The obtained collection are known under the nickname Folksonomy. As these systems grow larger, however, the users address the need of enhanced search facilities. Today, full-text search is supported, but the results are usually simply listed decreasingly by their upload date. Challenging research issue is therefore the development of suitable prediction framework to support users in effectively retrieving the resources matching their real search intents. The primary focus of this paper is to propose a new users’ search intent prediction approach for query tag suggestion. Specifically, we adopted Hidden Markov Models and triadic concept analysis to predict users’ search intents in a folksonomy. Carried out experiments emphasize the relevance of our proposal and open many issues.KeywordsHidden Markov Models folksonomies Search intentTriadic concepts analysis
AÇÃO(ÕES)!

Tradução do texto: LUSSAULT, Michel. (2000) Action(s)! In: LÉVY, Jacques; LUSSAULT, Michel (Org.). Logiques de l’espace, esprit des lieux: géographies à cerisy. Paris: Belin, p. 11- 36.Cláudio Tradutores:Cláudio Smalley Soares PereiraUniversidade de Pernambuco (UPE) Petrolina, PE, Brasilhttp://orcid.org/0000-0002-4624-4057 Jean LegrouxUniversidade Estadual Paulista (UNESP), Presidente Prudente, SP, Brasilhttps://orcid.org/0000-0002-3811-4180 Revisão Técnica:João Carlos Carvalhaes MonteiroUniversidade Federal de Rondônia (UNIR), Porto Velho, RO, Brasilhttps://orcid.org/0000-0002-9550-4302
Attribution of dynamic and thermodynamic components in extreme weather and climate events

Extreme weather and climate events, such as heat waves, droughts and their combinations, are intrinsic aspects of the evolution of the climate system, and they can have substantial environmental and socio-economic impacts. Every extreme event is the result of a superposition of external drivers, natural and anthropogenic, and internal variability. Risk-based or probabilistic extreme event attribution assesses to what extent anthropogenic drivers modify the probability and magnitude, and hence the risk of an extreme event or a class of events to understand regional impacts of climate change. Surface conditions depend on the patterns of atmospheric circulation. Thus, in a specific region human-induced thermodynamic influence can be amplified or counteracted by human-induced change in the atmospheric circulation. The main goal of ANDANTE is to separate human-induced dynamic (i.e. circulation/flow) and thermodynamic contributions to the risk of selected extreme events in Europe and Africa. Since we are dealing with rare events we need large or even better very large ensembles of model simulations (~1,000 members) to do the flow-conditional probabilistic event attribution in statistically sound way (i.e. to get well-resolved probability distributions) with the methods of flow clusters (weather regimes/climate modes) and flow analogues. The project will make a key contribution to the development of the next-generation prediction and event attribution system. The produced new very large ensembles will be combined with the current-generation ensembles as well as multi-model climate simulations and multi-member reanalysis products to perform robust multi-method estimates of the univariate and multivariate (i.e. multi-variable) risk indicators. The risk assessment of selected extreme events manifested in surface temperature, precipitation, potential evapotranspiration and fire weather index can be useful to a wide spectrum of stakeholders interested in climate change impacts.
Metal-Organic frameworks as multifunctional materials toward p-sustainability

The efficient use of chemical fertilizers is essential to face the Sustainable Development Goal-2: Zero Hunger. Specifically, phosphorous-fertilizers are mainly produced by mining the non-renewable phosphate rock (PR), with both inefficient production and application processes causing dramatic environmental damages. 
A new European fertilizer regulation encourages the development of new strategies driving to a P-circular economy. Phosphate could be recovered from both waste/eutrophicated water to produce P-fertilizers. However, the prevailing recovery rates cannot satisfy the whole P-demand. Thus, novel methods for a more sustainable production of P-fertilizers are also urgently needed.
Zirconium-based Metal-Organic Frameworks (Zr-MOFs) are porous crystalline materials easy to functionalize showing large surface areas, water stability and a strong affinity to phosphate. Hence, they could act as promising P-recovery adsorbents. Besides, they have recently proved to promote the dissolution of highly stable minerals. Thus, they could enhance the dissolution of PR under milder condition, mitigating the environmental risks of PR-mining. Unfortunately, Zr-MOFs are usually prepared using toxic organic solvents, limiting their industrial progress. 
The project entitled “Metal-Organic Frameworks as multifunctional materials toward P-sustainability” (PSust-MOF) addresses the greener production Zr-MOFs with controlled particle features by using water as solvent. The main features determining both P-recovery process and promotion of apatite dissolution (main component of PR), will be identified. This knowledge will enable the design of advanced Zr-MOF materials which will be tested, for P-recovery or PR-dissolution, under real conditions. It is expected that the results of the project will not only have a strong impact on P-sustainability. Given the wide-range of applications of MOFs, the greener design of Zr-MOFs will also favour their industrial progress in multiple fields.
Neural sources of performance decline during continuous multitasking

Multitasking performance costs have largely been characterized by experiments that involve two overlapping and punctuated perceptual stimuli, as well as punctuated responses to each task. Here, participants engaged in a continuous performance paradigm during fMRI recording to identify neural signatures associated with multitasking costs under more natural conditions. Our results demonstrated that only a single brain region, the superior parietal lobule (SPL), exhibited a significant relationship with multitasking performance, such that increased activation in the multitasking condition versus the singletasking condition was associated with higher task performance (i.e., least multitasking cost). Together, these results support previous research indicating that parietal regions underlie multitasking abilities and that performance costs are related to a bottleneck in control processes involving the SPL that serves to divide attention between two tasks.
Empty Argument Insertion in the Hindi PropBank

This paper examines both linguistic behavior and practical implication of empty argument insertion in the Hindi PropBank. The Hindi PropBank is annotated on the Hindi Dependency Treebank, which contains some empty categories but not the empty arguments of verbs. In this paper, we analyze four kinds of empty arguments, *PRO*, *REL*, *GAP*, *pro*, and suggest effective ways of annotating these arguments. Empty arguments such as *PRO* and *REL* can be inserted deterministically; we present linguistically motivated rules that automatically insert these arguments with high accuracy. On the other hand, it is difficult to find deterministic rules to insert *GAP* and *pro*; for these arguments, we introduce a new annotation scheme that concurrently handles both semantic role labeling and empty category insertion, producing fast and high quality annotation. In addition, we present algorithms for finding antecedents of *REL* and *PRO*, and discuss why finding antecedents for some types of *PRO* is difficult.
ELEVATOR LINK COMPENSATOR SYSTEMS AND METHODS

Embodiments of the present disclosure are directed to systems and methods for running casing into a wellbore with a casing running tool (CRT), such as a casing drive system (CDS), that is equipped with single joint elevator links and elevators. For example, in certain embodiments, a system includes a joint elevator configured to engage a joint of a tubular element. The system also includes an elevator link comprising an upper link and a lower link. The lower link is configured to couple to the joint elevator. In addition, the lower link is configured to fit telescopically within the upper link. The system further includes a compensator cylinder configured to couple to the upper link and the lower link, and configured to adjust a position of the lower link with respect to the upper link.
Building integrated health care through the use of ICT solutions in home care

The HEALTHNET project aims at defining innovative integrated care model and at developing policies shared at cross-border level on home-care for the wellbeing of citizens, through comparative analysis, training and pilot activities implementing ICT- and social innovation. The three involved Regions have already implemented cooperation projects that will feed this new proposal. Starting from the results and lessons learned from the previous experiences, the partners foresee to set-up an institutional cooperation in order to develop transferable and sustainable integrated care models with the following objectives: to improve the integration and continuity between hospital and primary care, to strengthen the capacity of independent living for people with chronic diseases mainly in the post-discharge phases through ICT-solutions (eHealth and eCare) and training activities for formal and informal carers. _x000D_
_x000D_
The project addresses crucial issues of the Italy-Austria Programme area, such as an ageing population with ageing rates higher than the EU average, the reform of health regional systems, the increasing cost of health care.
Trade at the sea of the rising sun: neo-elamite commercial involvement in the persian gulf network (1000-525 bc)

Since the 3rd millennium BC, the Persian Gulf has been a key international trade route both connecting the civilisations around it, such as Elam, Mesopotamia, Dilmun and Magan, and orienting these societies towards the Indian Ocean. The lack of diversity in natural resources on both sides of the Gulf motivated early Middle Eastern states to explore maritime trade in order to obtain and exchange raw materials and finished products (e.g. copper, timber, textiles). Especially, littoral societies on the shores of the Gulf shared a maritime culture based on long-distance trade, and were part of an interlinked system that included agricultural villages and oases that sustained the caravan trade.  In order to achieve a deeper understanding of interregional contacts between Elam, Mesopotamia and Eastern Arabia, one requires a profound knowledge of the political climate promoting commercial exchange, the maritime and overland trading itineraries, the import and export products, and the people involved in these commercial networks. TRADElam aims to study the commercial relations and trading networks in the Gulf region during the 1st half of the 1st millennium BC. While there is abundant maritime traffic recorded for the 3rd-2nd millennium BC, traces of Gulf commerce become scarce in the early 1st millennium BC. The first part of the project will therefore create a general overview of the commercial networks between Elam, Eastern Arabia and Mesopotamia during the 1st half of the 1st millennium BC. To achieve this, one will study the maritime and overland trade routes and identify the natural resources as well as the import and export products of each region. The second part will focus on the role of the indigenous coastal communities involved in these commercial relations.
SPECIAL YARN SPINNING APPARATUS IN SPINNING MACHINE

A special yarn spinning apparatus adapted for use in a spinning machine includes a plurality of apron draft devices that are configured to switch fiber bundles to be fed, respectively. The special yarn spinning apparatus further includes a joining device and an anti-twist device. The joining device joins a training end of the fiber bundle fed from at least one of the apron draft devices which has operated before switching the feed and a leading end of the fiber bundle fed from another of the apron draft device which has started after switching the feed. The anti-twist device holds and delivers the fiber bundle at a position downstream of the joining device to prevent propagation of twist from a twist device to the joined fiber bundles in the joining device.
Russian Science: Waking From Hibernation

Late last month, Russia's Ministry of Education and Science announced the first results of a novel attempt to revitalize science in the country's universities. It had offered megagrants of up to $5 million to attract top researchers from around the world to set up new labs at Russian universities. How much the megagrant winners can boost Russian science remains an open question, however. Foreign winners are only required to spend one-third of each year in Russia, and the program notably failed to lure two big fish: this year's winners of the Nobel Prize in physics, Andre Geim and Konstantin Novoselov. The discoverers of graphene were both born and educated in Russia but are now working at the University of Manchester in the United Kingdom. Indeed, the Nobel Prize announcement last month generated much debate in Russia about why many of the country's best and brightest scientists—tens of thousands of whom fled abroad during the economic crises of the 1990s—are still now gracing foreign universities and their work benefiting other economies.

* With reporting by Jennifer Carpenter, Andrey Allakhverdov, and Vladimir Pokrovsky.