SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Analysis of Medical Resource Utilization and Outcome of Inhaled Nitric Oxide in Patients Undergoing Mechanical Ventilation

Inhaled nitric oxide (iNO) is a potent selective pulmonary vasodilator, which is used in critically ill patients to improve oxygenation. It avoids systemic hypotension and ventilator-induced lung injury in patients using ventilators. This study explored the medical resource utilization and outcome, and predicted risk factors for mortality in patients using ventilators with iNO. The database was from the National Health Insurance hospital claims data in Taiwan from 2004 to 2009. The patients using ventilators with iNO were collected and stratified by age to 20–44 years, 45–64 years, 65–74 years, and ≥ 75 years. Seven hundred and thirty ventilator patients with iNO were enrolled (63.15% male, mean age 60 years). Mechanical ventilation (MV) weaning rate was 18.25%, intensive care unit (ICU) readmission rate was 5.75%, and ICU mortality rate was 74.52%. ICU mortality rate was lower, case-mix index, MV weaning rate, and hospital costs were higher for patients aged 20–44 years and 45–64 years than in those aged 65–74 years and ≥ 75 years ( p < 0.05). Sex, case-mix index, Charlson comorbidity index, whether MV weaning ( p < 0.001), different age group, and implementation of tracheostomy ( p < 0.05) were all significant risk factors in predicting mortality of patients using ventilators with iNO. This study showed that the outcome differed with age in patients using ventilators with iNO.
Short-Chain fatty acids in brain neuroinflammation: modulators of immunity and neural stemness

The human gut hosts trillions of microbes collectively called the microbiota, which secretes metabolites that have been strictly linked to the regulation of physiological functions. Among them, short-chain fatty acids (SCFAs) play a key role. Many pathologies are associated with microbiota alterations, including multiple sclerosis (MS), a brain autoimmune disease representing a major public health challenge in Western society. Although preliminary studies in mouse models showed that SCFAs have multiple actions, including immunomodulatory function and influencing the differentiation of stem cells, we still miss a comprehensive study that correlates mechanistically how changes in the microbiota, and, as a direct consequence, in SCFAs, favor autoimmunity in the central nervous system (CNS). Thus, in BRAINeSs, we propose to analyze the effect of SCFAs on different components of the CNS, to unravel the complexity of their action. Particularly, we will look at the impact of SCFAs on the integrity of the blood-brain barrier, immune cells, neural stem/precursor cells, mature neurons, and glial cells. BRAINeSs will allow us to broaden the analysis on the impact of SCFAs in MS through a multidisciplinary approach that spans from metabolomics to immunology, neuroscience, and bioinformatics, and takes advantage of cutting-edge methodologies, as single-cell RNA sequencing and human brain organoid culture. Our plan of research could be applied as a model for the study of other neuroinflammatory or neurodegenerative diseases and could lead to a new therapeutic perspective. I will gain new technical and soft skills through advanced training, necessary to reach full independence. BRAINeSs addresses the third UN development goal, “good health and wellbeing”, and strengthen the interest of the EU for microbiota and multiple sclerosis studies. BRAINeSs is compliant with the Work Program of H2020, which lean toward open-access science, and dissemination/public engagement activities.
Microlab lab-on-a-cartridge, a disruptive concept. towards an innovative solution for food safety

The main aim of this proposal is to generate an updated revision of GTZ’s initial Business Plan (BP I), to overcome the main challenges detected for the successful MicroLAB market launch. The following aspects will be pursued: 1) specific marketing tools and sales strategy (Europe, North and South America, Asia) devoted to feedstock producers and micro & small food companies (≤50 employees), to speed up, the market share achievement (2,6%); 2) product innovation policy to assure the company growth in the food safety business; 3) technical feasibility study for a cost-effective production process (<5 €/device) and its lay-out definition; 4) revision of the organization growth plans to assure its sustainability; 5) and an updated review of the economical and financial plans. The food sector is the second largest manufacturing industry micro, small and medium sized companies suppose the 99. The business size profile has a relevant impact on the deployment of the safety assurance measures and the feedstock sustainable production (minimization of waste and GHGE). Due to the micro and most of the small companies’ size (< 20 employees), the accomplishment of the mandatory plans for quality and food safety assurance, makes of it a big hurdle difficult to overcome. Alternative rapid kits have been developed to facilitate food pathogen assessment, but none of them, covers the whole microbial detection routine in an easy and affordable way. So, micro and small food companies ought to outsource this service (18-20 €/test, 8,500 €/year), with the added drawback of relying a very sensitive issue in third parties. The small dairy, meat and poultry farms, can’t cover these controls, being assumed by the secondary transformers, with the additional costs of logistics, cross-contamination and factory’s stops, if feedstock refuse. The solution has been carefully considered, and it’s a challenge that GTZ is eager to assume, by the manufacture and the market launch of MicroLAB.
PEPTIDE AGONISTS OF PROSTATE-SPECIFIC ANTIGEN, AND USES THEREFOR

This invention relates to isolated peptides comprising agonist epitopes of prostate-specific antigen (PSA). In various aspects, the invention relates to peptides comprising agonist epitopes of the PSA-3 cytotoxic T lymphocyte epitope, and nucleic acids encoding peptides that comprise PSA-3 agonist epitopes. Also related are probes, primers, and vectors comprising these nucleic acids, as well as host cells comprising these vectors, and antibodies that bind to the PSA-3 agonist peptides. This invention further relates to diagnostic reagents and methods utilizing the disclosed nucleic acids or antibodies. The invention also relates to pharmaceutical compositions comprising the nucleic acids, host cells, and peptides of the invention, as well as methods of treatment or prevention of prostate cancer employing such compositions, for example, for peptide-mediated, cell-mediated, and vector-mediated immunotherapies.
The role of battle narrative in the Bellum Gallicum

This thesis examines the role of battle narrative in the Bellum Gallicum, to show that these
passages, including contextual information, are fundamentally persuasive in nature as they are
integrated into Caesarʼs various self-promotional aims. To date a comprehensive analysis has
not been undertaken of battle, and where it has been examined by military historians,
investigations have often relied on the idea that these passages are primarily designed to
reconstruct the details of the historical event. The thesis instead uses case studies to show
these passages are not merely an attempt to describe historical events, but are fundamentally
influenced by the desire to influence the audience. This can be a simple matter of reception,
whether through the building of tension in the narrative, or the creation of a compelling
account of a particular battle. More often however battle is used in conjunction with the
campaign narrative to create an impression, or support an argument regarding Caesarʼs
interpretation of the episode, as battles are part of the interpretive structure of the text, where
information conveys his self-promotional objectives. Furthermore, a major objective of these
accounts is to support Caesarʼs view of the various characters portrayed, and the narrative is
used to create or encourage views of the individuals and peoples involved. Unsurprisingly, the
most important figure represented in battle is Caesar, and self-aggrandisement or the
deflection of criticism shapes the structure and content of these narratives at a fundamental
level. A detailed analysis of these passages, and their relationship to the book in which they
appear shows how Caesar structures battle narrative for self-promotion in various ways. Not
only does such an examination reflect on the way that battle and other military information is
presented, but it enables insight into the purposes that he had while writing these passages,
and the extent to which he was willing to utilise battle narrative in the pursuit of the self promotional
objectives of the work.
Enhancing economic impact in sme's in romania by building innovation management capacity

The objectives of this proposal are the following:Increase efficiency and effectiveness of innovation processes of local beneficiaries of SME instrument and SMEs with significant innovation activities and high potential for internationalisation;Facilitate SME’s access to consulting services for innovation management to address bottlenecks to creation of economic impact;Support innovative SME’s to raise the company’s profitability and competitiveness on international markets.Partners deliver 2 specifically targeted service packages and base their approach on complementary experience and know-how as EEN members.The proposal also includes a general management WP consisting of coordination,communication,dissemination and quality check measures.The WPs dedicated to SMEs consist of preliminary steps (customer identification and approach, meetings), assessment of needs and gaps (specific questionnaires based on CEN/TS16555-1 Standard),assignment of innovation experts and lead coaches and supply of tailored services or facilitation of SME-coach interaction.The proposal addresses challenges such as lack of investment in research, lack of innovation management systems,insufficient supply of innovation services,unaffordable market prices.The scope of the project is to eliminate the barriers for SME innovation by supplying 7 days services.Taking account of the ongoing global crisis, innovation process from idea generation to innovation result but also leadership, management skills and other enabling factors like the ability to cooperate with third parties are considered an essential driver for development and economical recovering. The crisis is depressing investments in innovation as the first costs to be cut and particularly SMEs are concerned by this as they do not have internal resources, nor strategic vision to face the market competition.Methodologies and tools of partners complement each other and help companies manage innovation processes efficiently.
«SESTRICAR S.R.L.»

L’INTERVENTION CONSISTE EN L’ACHAT D’UN MOD DE CABINE DE PEINTURE. THÈSE AVEC TECHNOLOGIE ENDOTHERMIQUE + 1 ZONE DE PRÉPARATION RAPIDE PK 4000 ET DIVERSES OPTIONS, BOÎTE À TEINTES N.1. LA CABINE DE THÈSE EST UN SYSTÈME TOTALEMENT INNOVANT QUI MODIFIE COMPLÈTEMENT LE CONCEPT ET LA MANIÈRE D’UTILISER LES CABINES DE PEINTURE QUE NOUS AVONS JUSQU’ICI HABITUÉES À CONSIDÉRER. LES PANNEAUX ENDOTHERMIQUES SONT NÉS POUR LA PEINTURE AVEC DES PRODUITS À BASE D’EAU, MAIS LEUR UTILISATION EST FORTEMENT RECOMMANDÉE POUR TOUS LES TYPES DE PEINTURE. USINE ÉQUIPÉE DE PANNEAUX ENDOTHERMIQUES. L’ABSENCE DU BRÛLEUR ET DE L’ÉCHANGEUR DE CHALEUR REND LES TUYAUX D’ÉJECTION DE FUMÉES, LA CONSTRUCTION DE CENTRALES THERMIQUES REI 120 ET DES DÉPÔTS INUTILES. IL Y A AUSSI TOUS LES TRAVAUX DE MAÇONNERIE SIMILAIRES CONSISTANT EN L’ADAPTATION DE L’ATELIER POUR RÉPONDRE AUX CHANGEMENTS INTRODUITS DANS LES LIGNES DE PRODUCTION ET POUR UNE REDISTRIBUTION DES ESPACES AU SEIN DE L’UNITÉ DE PRODUCTION.
Does public investment stimulate private investment? Evidence for the euro area

Abstract This paper explores the long run relationship between public and private investment in the euro area. In contrast to previous studies a stock-flow approach is applied to control for the different orders of integration between the stock and flow variables. Panel econometric techniques allowing for international spillovers are employed. Private and public capital stocks are both I (2) and cointegrated. The deviations from the stock equilibrium are not (trend) stationary, but I (1). Utilizing them in a model for investment flows improves the cointegration evidence between the I (1) variables. In fact, private investment flows, GDP and the real interest rate appear to be cointegrated only if the deviations from the stock equilibrium are included. The corresponding error correction equation is well behaved. Therefore, knowledge of the stock relationship is crucial to explain the changes in private investment flows. Overall, the lack of public investment may have restricted private investment and thus GDP growth in the euro area. The results have strong implications for the future direction of fiscal austerity programs to combat the euro area debt crisis.
METHOD AND ARRANGEMENT FOR A LOW RADAR CROSS SECTION ANTENNA

The invention provides a low-RCS (Radar Cross Section) antenna structure for an Active Electrically Scanned Antenna, AESA, comprising an AESA enclosure and at least two antenna elements. Said antenna elements being arranged to be mounted on a front surface of the AESA enclosure and embedded in a lightweight structure, where the front surface and side surfaces of the AESA enclosure and the antenna elements are arranged to be covered with the lightweight structure. A thin laminate is arranged to cover an outer top surface and an outer side surface of the lightweight structure. Parts of the lightweight structure is arranged to be doped with a lossy material having dielectric, magnetic and/or resistive losses, thus making these parts of the lightweight structure absorbing for electromagnetic radiation.
Contribución a técnicas de modelado y reducción de EMI en sistemas multiconvertidor

This Thesis has been developed in the research group TIEG (Terrassa Industrial Electronics Group). It is focused on the reduction of conducted electromagnetic interferences (EMI) generated by switched power converters. Particularly, it deals with multiphase buck converters. In such kind of systems interleaving is commonly and widely used because of advantages it reports. Among these advantages, it should be mentioned the reduction of the output voltage ripple and conducted disturbances as well. However, interleaving can be combined with other techniques in order to improve the electromagnetic compatibility (EMC) performance. These methods can be classified as filtering or suppression techniques. Filtering methods prevent interferences from propagating through mains, power lines, data lines, etc. Suppression methods directly suppress the noise source. The modulation of the switching pattern of the converter is one of such techniques. These suppression techniques are complementary to the conventional filtering techniques based in passive elements.
The aim of this Thesis is to determine the optimum combination of both techniques (interleaving and modulation) in order to achieve the best attenuation of conducted disturbances. The influence of several modulation parameters on the attenuation will be investigated and the undesired side effects produced by these new techniques will be evaluated as well. In order to fulfil this goal, several modulation strategies were considered. Particularly, the switching frequency modulation (SFM), pulse position modulation (PPM) and pulse width modulation (PWM) have been investigated. Finally, three modulation techniques based on the frequency modulation of the switching pattern have been proposed. These techniques are the Constant Delay Tm with switching Frequency Modulation (CDFM-Tm), Constant Delay Tc with switching Frequency Modulation (CDFM-Tc) and Variable Delay with switching Frequency Modulation (VDFM). The experimental validation of these 3 techniques has been conducted on a 4 phases buck converter operated in hard switching regime.
ARREDO IN POROTEX

LA PROPOSTA PROGETTUALE MIRA A STUDIARE E SVILUPPARE UNA INNOVATIVA LINEA DI PRODOTTI DI ARREDO IN POROTEX (MOBILI PER LA CASA E PER LÂ¿UFFICIO, DIVISORI E COMPLEMENTI DI ARREDO) CONFIGURABILI IN MODO DA ESSERE PERSONALIZZATI SECONDO LE SPECIFICHE ESIGENZE DEL CLIENTE, CHE POTRÃ  ESSERE SIA IL CONSUMATORE FINALE, CHE AVRÃ  ACCESSO AL CATALOGO ONLINE, SIA DESIGNERS ED ARCHITETTI DI INTERNI E DI ESTERNI, CHE SI OCCUPANO DI CREARE NUOVI PRODOTTI PER PARTICOLARI CONTESTI  (RESIDENZIALI, COMMERCIALI E DIREZIONALI). TALE NUOVA LINEA DI PRODOTTI SARÃ  DOTATA ANCHE DI ILLUMINAZIONE INTEGRATA, COERENTE PER FORMA, DIMENSIONI E PRESTAZIONI OFFERTE SIA CON LÂ¿ESTETICA E LE FUNZIONALITÃ  DEL MOBILE/COMPLEMENTO DI ARREDO SIA CON LE RICHIESTE DEL CLIENTE. LA CONFIGURABILITÃ  DELLA LINEA COMPORTA LA PERSONALIZZAZIONE DEI PRODOTTI IN TERMINI DI DECORAZIONI PRESENTI, COLORAZIONI, TIPO DI ILLUMINAZIONE (O IN ALCUNI CASI ASSENZA) E DIMENSIONI.    DA UN PUNTO DI VISTA DEL CICLO DI VITA DELLA NUOVA LINEA, I
Apply ligninases to resolve end-of-life issues of thermoset composite plastics

BIZENTE project presents an innovative solution to resolve the end-of-life of thermoset composites based on the development of a new technology focused on a controlled enzymatic biodegradation. BIZENTE technology will contribute to decrease the amount of non-biodegradable polymers currently discharged to the environment or sent to landfill and incineration in at least a 40%. The solution will imply opening a biocatalytic process to new type of feedstock (3 thermoset resins and composites) not previously approached in the plastics value chain.
BIZENTE will determine directed enzyme evolution strategies to improve ligninolytic oxidoreductases which have been selected as the most suited biocatalysts to degrade the three types of thermoset composites addressed in the project (epoxy, polyester and vinylester). Once this new technology has been optimised and scaled-up to a pilot environment, the biodegradation products will be valorised into new building blocks for the chemical industry.
BIZENTE project will directly contribute to achieve SIRA’s in KPI1, KPI2 and KPI8. BIZENTE consortium involves 10 partners: 3 RTD (Aitiip, UCA and TuDelft), 5 SME (EvoEnzyme, BSP, SP, PLATA and ECRT), and 2 Large Companies (ACCIONA and AED), accounting to 1 BIC full member (BIOPHERE) and 3 associated (AITIIP, UCA, TUDELFT). It involves partners from 5 EU countries (ES, NL, FR, IT, DK). The 48-months proposed will comprise a total estimated budget of 3,182,571 €; being the 21,2% covered by consortium own contribution (in-kinds) and adding 223,764.5 € in additional activities during the project implementation and 2,350,000 € envisaged to upgrade TRL after the end of the project. Benefits will be significant in terms of EU growth (13,1%) and increasing jobs (16 direct, 1000 indirect) by promoting at least 2 new sector interconnections in the new created “enzymatic circular VC for composite materials”.
A soft sensor for carbon content of spent catalyst in a continuous eforming plant using LSSVM-GA

Continuous catalytic reforming (CCR) is an important process in hydrocarbon processing to convert low-octane gasoline blending components to high-octane components for use in high-performance gasoline fuels or as source of aromatics. Carbon deposition rate is a critical performance factor of reforming catalyst and carbon content of spent catalyst would directly influence the subsequent catalyst regeneration; thus it is imperative to monitor the carbon content of spent catalyst in real time. In this paper a soft sensor is proposed using least squares support vector machine (LSSVM) with genetic algorithm (GA) to solve the industrial problem for online estimating the carbon content of spent catalyst in an existing CCR plant, wherein the GA is used to select the free parameters of the LSSVM model. The LSSVM with traditional grid algorithm and artificial neural network (ANN) are also applied to model two soft sensors using the same data sets for comparison. The simulation results show that GA shows outstanding performance than traditional grid algorithm for selecting free parameters of LSSVM; the proposed LSSVM-GA soft sensor can achieve smallest errors and shortest computing comparing with LSSVM and ANN. Then the proposed soft sensor is applied to the existing CCR plant; the predictive values are satisfactory.
Relazioni tra Beni Culturali e Infrastrutture. Analisi e mappatura per la valorizzazione dei territori intermedi tra Torino e Milano

The current research aims at investigating how to promote better relationships between infrastructure and cultural heritage, with a more general objective to improve new ways to access and effectively use the places that are located in the surrounding landscape of infrastructure. The main goal of research is a visual representation methodology that is able to show, at a territorial scale, how cultural heritage and landscapes can be connected to main infrastructural nodes and to the cities, in order to enhance the accessibility of these places for tourists and local inhabitants. In the first part of the research general issues related to the state of art and to three different international case studies (The New Water Defence Line - Netherlands, The Emscher Park - Germany, and The French Motorways - France) have been analyzed with the aim to understand how other Countries have faced with the same problems. The analysis of the case studies allows a better understanding of the research problem, but also a broader comparison with other territorial contexts. The second part of the thesis deals with methodological aspects which are applied to a real case study that has been identified into the territories in-between Turin and Milan, that are crossed by an important infrastructural bundle. Entering more in detail, the research tries to combine a top-down approach, based on GIS density analysis, with a bottom-up approach, based on GPS survey technique. Visual mapping techniques show the importance to make new cartographic representations in order to visualize specific phenomena related to cultural heritage distribution and localization. The density maps represent such particular distribution and configuration of cultural heritage points, showing in a very effective way, which areas could be selected to apply new valorization strategies. In the second part , there is also a dissertation on GPS tracking technologies as new tools to track, to record and to map new landscape structures, such as cultural routes, that can be used to give value to the territories in-between Turin and Milan. Different maps and schemes show the outcomes related to the different approaches, developed at local and territorial level. The research outcomes can be divided into two parts. The first one deals with infrastructural nodes, heritage areas and cultural routes, as new territorial elements, which can contribute to the valorization of intermediate territories. The second part concerns with methodological aspects related to the integration of GIS and GPS techniques, as new platform of knowledge to support spatial planning strategies, in the field of cultural heritage valorization