SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
177mLu impurity: Practical aspects of 177mLu hospital waste management

1248 Objectives In our facility we performing weekly up to two treatments with a standard dose of 7,5 GBq [Lu-177][DOTA0, Tyr3]octreotate. Due to the similar half-lives I-131 ( t1/2=8 d), Lu-177 ( t1/2= 6,7 d) and Y-90 (t1/2=2,6 d) were released in one tank. Depending on the production route there could be impurities of durable 177mLu (t1/2= 160 d) which prevents the timely release of the waste. The aim of our study was the development of a conversion method of the liquid wastes into gel the resulting possibility of disposal at the national collection point. Methods 10 GBq 177Lu-DOTA-tate (n=3)were prepared with an automatic synthesis unit. After the nephroprotectic infusion of 1,5 l Aminosteril N-Hepa 8% 7,5 GBq [177Lu][DOTA0,Tyr3]octreotate were administered. The excreta of the patient were collected within the first 24 h and the volume and activity was measured. The absorption behavior of super-absorbers for water, NaCl and urine was estimated. Storage for a period of 3 months was tested. Results The labeling results in radio-chemical yields ≥ 98 % and a total volume of 20 mL. We found that the precipitated volume was 2,42 ± 0,18 L containing 74 ±2,2 % (5602 ± 166 MBq) of the administered activity. Based on this data’s, an accumulation of approximately 10GBq 177Lu and 12 MBq 177mLu at the end of 40 days were calculated. The superabsorber showed a absorber-volume ratio for water of 0,013 and for sodium chloride which is similar to urine of 0,02 . No changes in the properties or release of activity could be observed Conclusions Because of the high activities of 7,5 GBq per patient and the resulting amount of ~ 3 MBq 177mLu the waste has to be collected separately. The conversion from liquid to solid form using superabsorbers guaranteed an easier and saver handling, storing at smaller space as well as uncomplicated collecting, shipping and deposition for decay. But the most important argument is the huge financial savings per year.
Quantifying the potential effects of high-volume water extractions on water resources during natural gas development: Marcellus Shale, NY

Abstract Study region The Marcellus Shale, New York State, USA. Study focus Development of natural gas resources within the Marcellus Shale will require large volumes of water if high-volume hydraulic fracturing expands into New York State. Although this region has ample fresh water resources, it is necessary to explore the response of hydraulically connected groundwater and surface water systems to large withdrawals. Because such effects would not be apparent from a typical water budget approach, this study applied groundwater flow modelling under scenarios of high-volume water withdrawals. Emphasis on water quantity, in contrast with other lines of research concerning water quality, introduced an important perspective to this controversial topic. New hydrological insights for the region The potential effects of the withdrawal scenarios on both the water table and stream discharge were quantified. Based on these impact results, locations in the aquifer and stream networks were identified, which demonstrate particular vulnerability to increased withdrawals and their distribution. These are the locations of importance for planners and regulators who oversee water permitting, to reach a sustainable management of the water resources under changing conditions of energy and corresponding water demand.
A single high-resolution HLA mismatch has a similar adverse impact on the outcome of related hematopoietic stem cell transplantation as a single low-resolution HLA mismatch

The relative importance of the resolution level of HLA typing has not been fully defined for related donor transplantation. To address this question, we retrospectively evaluated patients who underwent a first related hematopoietic stem cell transplantation (HSCT) from 2000 to 2011 from an HLA high-resolution matched (MRD, n = 2,244), high-resolution 1 locus-mismatched (HR-MMRD, n = 116), or low-resolution 1 locus-mismatched related donor (LR-MMRD, n = 396) in the graft-versus-host direction at three loci (HLA A, B, and DRB1) using the database of the Japan Society for Hematopoietic Cell Transplantation. The median age was 40 years (0-74). The median follow-up duration of surviving patients was 950 days. Although the cumulative incidences of grade III-IV acute graft-versus-host disease (GVHD) in the HR-MMRD and LR-MMRD groups were significantly higher than those in the MRD group (HR-MMRD 19.8%, LR-MMRD 20.4%, and MRD 9.5%), there was no statistically significant difference between the HR-MMRD and LR-MMRD groups (P = 0.65). Although both HR-MMRD and LR-MMRD were significantly associated with an increased risk of non-relapse mortality and a worse overall survival, there was no statistically significant difference between the HR-MMRD and LR-MMRD groups. In conclusion, LR-MM and HR-MM have a similar adverse impact on the outcome in related HSCT.
Systematic analysis of pacific phytoplankton and islands regional effects

Phytoplankton, the tiny algae that fix carbon dioxide via photosynthesis, represent the base of the oceanic food chain and support essentially all life in the oceans. In the tropical Pacific, where phytoplankton biomass is low, local nutrient enrichments near islands support ecosystems characterized by higher biomass and biodiversity. While this ""island effect"" has been known for 60 years, the vast majority of islands remain unstudied and impacts at the basin scale are unknown. Additionally, little is known regarding changes in phytoplankton community structure despite implications for higher trophic levels. The SAPPHIRE project will elucidate the impact of islands on phytoplankton by conducting the first systematic study of the island effect in the tropical Pacific from a suite of physical and biological satellite data. This project leverages the OUTPACE in situ 20°S transect that sampled phytoplankton community composition nearby several islands in 2015 and the breakthrough satellite-based PHYSAT method that detects phytoplankton functional groups from space. Novel methods identifying and characterizing the island effect will be first developed in the OUTPACE region from in situ and satellite data, then applied to the entire tropical Pacific using satellite data. The ultimate goals are to 1) quantify the impact of islands on phytoplankton and physics in the tropical Pacific and 2) classify the islands as a function of enrichment processes and phytoplankton responses using cutting-edge machine learning techniques. SAPPHIRE provides a highly original perspective on marine ecological research by systematically conducting thousands of small-scale process studies over a large area, effectively providing a large-scale assessment of a mesoscale process. This project will be an important step in my career development by establishing me as a leading scientist in the emerging field of multidisciplinary data-intensive oceanography in Europe.
Artes visuales para la inclusión de la diversidad sexual en la formación del profesorado de educación primaria

In this paper, we propose training primary school teachers on issues of sexual diversity. As the main objective, we propose to know if future primary school teachers are receiving this type of training, subsequently providing proposals to improve this situation of formative precariousness that exists regarding the inclusion of sexual and gender dissidence in school. Among the secondary objectives, we highlight the need to use attractive tools to deal with these issues in the classroom. We observe that, in relation to sexual diversity, visual arts and art education offer us the opportunity to incorporate images, works and artists who are working on these issues, using as a tool the Museari online museum. We use the case study as a methodology. After having incorporated these actions in the classroom, all the participants respond a questionnaire. After the results, the conclusion we draw is that the training experience in sexual and gender diversity and inclusion has been interesting and novel for them, having encouraged reflection on how to incorporate these issues into the dynamics of the primary school classroom.
ILLUMINATED ASSEMBLY FOR A SWITCH/OUTLET

An illuminating apparatus for a wall switch (20) or outlet (2) that has a pair of terminals (4, 5) across which an electric potential is available, including an electroluminescent lamp plate (17) having first and second electrode deposits (14, 15) on a surface thereof, and a contact plate (12) disposed between the wall switch (20) or outlet (2) and the electroluminescent lamp plate (17) and a back surface facing the switch (20) or outlet (2), the contact plate (12) having first and second conductors (3, 6), each of which pass through the contact plate (12) and one of the terminals (5), and the second conductor (6) contacting the second electrode deposit (15) and the other of the terminals (4).
INTRODUKSI PENGOLAHAN SELE KACANG TANAH SEBAGI PANGAN KAYA NUTRISI DAN ENERGI DI DESA NEGARI KLUNGKUNG

ABSTRACT Almost all of the production of peanut in Indonesia is locally consumed. The peanuts are consumed in various ways, mostly through direct consumption such as boiled peanut, fried peanut, roasted peanut, peanut convectors and peanut butter.Peanut Butter is by far the most important product made from peanuts. It is the pasta forming food that is usually consumed with bread. Peanut Butter is the most popular as a high and medium class food and almost found it at the restaurant and supermarket in Indonesia. However, to process peanut butter is not so difficult for everybody who wants to do it. Peanut Butter processing is very simple with the equipment and ways properly such as to prepare good quality peanuts, sorted, drying, testa separated, grounding and boiling with mixing sugar and salt. Peanut butter has a high calorie with a good nutrition such as protein, fat, vitamins and trace element like calcium, zinc and magnesium. Reformulation and process improvement of Peanut Butter had been done at Department of agricultural products technology, Udayana University and had been disseminated to the housewife’s group and farmer’s group in Negari Village. Through the technology transfer of the Peanut Butter processing, we hope will be achieved a good quality and many several of peanuts processing in the future.
The Tightly Super 2-extra Connectivity and 2-extra Diagnosability of Locally Twisted Cubes

Connectivity plays an important role in measuring the fault tolerance of an interconnection network [Formula: see text]. A faulty set [Formula: see text] is called a g-extra faulty set if every component of G − F has more than g nodes. A g-extra cut of G is a g-extra faulty set F such that G − F is disconnected. The minimum cardinality of g-extra cuts is said to be the g-extra connectivity of G. G is super g-extra connected if every minimum g-extra cut F of G isolates one connected subgraph of order g + 1. If, in addition, G − F has two components, one of which is the connected subgraph of order g + 1, then G is tightly [Formula: see text] super g-extra connected. Diagnosability is an important metric for measuring the reliability of G. A new measure for fault diagnosis of G restrains that every fault-free component has at least (g + 1) fault-free nodes, which is called the g-extra diagnosability of G. The locally twisted cube LTQ n is applied widely. In this paper, it is proved that LTQ n is tightly (3n − 5) super 2-extra connected for [Formula: see text], and the 2-extra diagnosability of LTQ n is 3n − 3 under the PMC model ([Formula: see text]) and MM * model ([Formula: see text]).
Autonomous, self-loading and unloading ground-based robots

Despite rapid advancements in the way that we receive packages, current last mile delivery solutions are still antiquated in comparison to the technology that has been deployed in other sectors of the industry. This causes PROBLEMS: for end consumers (failed deliveries, damaged items), for businesses (unsustainable costs for delivery) and for society and the environment (traffic congestion, pollution). 

To solve this, Eliport is creating a  fleet of AUTONOMOUS ground-based ROBOTS. They  will  travel  in pedestrian  spaces in order to cover  the  distance  between  the  pick-up  point  (e.g  final  logistics  point)  and  the  drop-off  point  (e.g  the  customer’s  home). The robot will be intelligent because software will allow it to do its delivery duties, orient in the environment and be a smart participant in human traffic. 

We are also developing a delivery receptacle. This trunk or gate system will be installed at/in customer’s premises and will only be accessible to Eliport autonomous robots, the intended recipient of the delivery or somebody with a unique code for each trunk/gate (e.g courier, mailman). With this PATENT-PENDING delivery system we are aiming to completely remove the human from the delivery process.

The ELIPORT system has many different potential use cases that vary in technical difficulty: limited open environments such as gated communities, closed industrial environments like warehouses and factories, public industrial environments such as airports and hospitals and finally fully open environments like typical suburban or urban residences. The first target market will be gated-communities in the EU and USA that contain primary residences.

The feasibility will determines three key requirements for further project execution: i) if the market conditions favor ELIPORT, ii) if the solution has reached the maturity needed to proceed to further product development and iii) if the company has the necessary resources to move on to the next phase.
Robustness of the Job – Finding, Job Loss (JFJL) Model in Modeling the Employment and Unemployment Rates of Ghana

The issues of employment and unemployment have become major macroeconomic factors that determine growth patterns of the modern Ghanaian economy. Periods of economic boom or growth of output can be associated with high rates of employment while recession periods correlate positively with woeful rates of unemployment. This undoubtedly suggests an inverse association between high rates of employment and recession; and high rates of unemployment and economic boom. This paper evaluates the robustness of the Job – Finding, Job Loss (JFJL) model in modeling the employment and unemployment rates in Ghana. It uses the job – finding and separation parameters as bases to model the employment and unemployment rates of Ghana in the form of simple Non – Homogenous First Order Ordinary Differential Equations. The resulting model is obtained by solving the differential equations via the Method of Variation of Constants (MVC). The JFJL model suggests an environment in which labour force is allowed to vary with time. It assumes a stable state equilibrium condition of the labour market which assisted in obtaining the same expressions as those for the natural rates of employment and unemployment. The predictive ability of the models is ascertained with real data obtained from the Ministry of Labour and Employment, which served as the inputs of simple input/output functions written in Microsoft Excel. The data cover labour force, employment, employment rates, unemployment and unemployment rates from the year 2000 through to 2014. The results evince the closeness of the predicted values or rates to the actual values or rates of employment and unemployment. In fact, at certain points in time especially getting to the end of the period (2013, 2014 and 2015), the model predicted approximately the same values and rates as the actual values and rates of employment and unemployment. Thus, the robustness of the JFJL model in predicting the employment and unemployment rates in the Ghanaian economy is established. Keywords: Employment and unemployment rates, Job – Loss, Job Finding model, Non –        homogeneous first order ordinary differential equations, Method of variation of constants, Ministry of Labour and Employment and Stable state equilibrium of the labour market
The geological characteristics of Jinjingzui skarn gold deposit and its causes in the east of Hubei province

Jin jing zui gold deposit is located about 2 kilometers south of Daye city,belongs to the Yangtze River metallogenic belt.Skarn is genetically related to magmatic intrusion into the Triassic Daye Formation limestones in the hydrothermal mineralization.The orogenic gold deposits in similar geological and geochemical characteristics,with the typical features of skarn deposits,the features of ore-control structure was the formation,structure,and buried fault of magmatic activity.According to its mineral composition and fabric characteristics of ore,ore-forming process of the deposit by the three mineralization of skarn stage,respectively,sulfide-on and supergene carbonate phase.Because mine has the typical features of skarn deposits and complete mineralization process,the other in the region skarn deposits provide references.
Indications for haematopoietic cell transplantation for haematological diseases, solid tumours and immune disorders: current practice in Europe, 2022

For over two decades, the EBMT has updated recommendations on indications for haematopoietic cell transplantation (HCT) practice based on clinical and scientific developments in the field. This is the eighth special EBMT report on the indications for HCT for haematological diseases, solid tumours and immune disorders. Our aim is to provide general guidance on HCT indications according to prevailing clinical practice in EBMT countries and centres. In order to inform patient decisions, these recommendations must be considered in conjunction with the risk of the disease, risk of HCT procedure and non-transplant strategies, including evolving cellular therapies. HCT techniques are constantly evolving and we make no specific recommendations, but encourage harmonisation of practice, where possible, to ensure experience across indications can be meaningfully aggregated via registry outputs. We also recommend working according to JACIE accreditation standards to maintain quality in clinical and laboratory components of practice, including benchmarking of survival outcomes. Since the last edition, the COVID-19 pandemic has affected clinical decision making and activity across indications. Although the full impact of the pandemic is yet to be determined, we recommend that decision making across indications is delivered with ongoing reference to EBMT and national COVID-19 guidance, in accordance with current local conditions.
The Application Research of Information Interactive Feedback Teaching Model in Wushu Routine Class

The present sports teaching model research is inevitably single functional and lack of interactive, the students can hardly encouraged which especially reflected in sports teaching model system research, meanwhile, it also weaken the operability of sports teaching model. Thus, it is necessary to combine practical teaching with sports teaching model during systematical research, and it is propitious to the sports teaching reform of our country. Though the construction and demonstration of information interactive feedback teaching model, this paper shows that: with student as subject and dominated by teachers, the information interactive feedback teaching model is a systematical model with the combination of teaching and learning, it can effectively improve teaching level, help to achieve teaching objectives and accomplish teaching tasks.
A single-molecule technology for resolving chaperone action in neurodegenerative diseases

A range of debilitating neurodegenerative disorders, including Alzheimer’s and Parkinson’s diseases, arise from the formation of amyloidogenic protein aggregates. Molecular chaperones can counteract aggregate formation, but their molecular action mechanisms remain poorly understood. This is chiefly due to the fundamental challenge of resolving heterogeneous and dynamic aggregating protein species in the presence of chaperones. In order to address this challenge and to advance our knowledge of chaperone action, I propose establishing µSPARK, a novel technology that will allow, for the first time, the unravelling of the detailed microscopic mechanisms by which chaperones target and disassemble amyloidogenic protein species in heterogeneous mixtures at the single-molecule level. These new insights will become possible through the first-time combination and seamless integration of two advanced technologies: (i) Miniaturized fluidic sorting devices and (ii) single-molecule fluorescence spectroscopy combined with three-colour coincidence detection. This will enable high-throughput single-particle interrogation of individual chaperone–aggregate complexes providing fundamentally new means for understanding key aspects of chaperone function. To demonstrate the new possibilities, µSPARK will be exploited to unravel the action mechanisms of heat-shock proteins in curtailing amyloid-β peptide and α-synuclein aggregation. This will provide new insights into proteostatic regulatory mechanisms in Alzheimer’s and Parkinson’s disease. The µSPARK technology will then be exploited to dissect—with high throughput and single-particle resolution—the molecular action mechanisms of small-molecule modulators that promote the inhibitory function of chaperones on protein aggregation. This will allow identifying new strategies to ameliorate aggregate toxicity and will pave the way for µSPARK to become a novel screening tool for drug development.
A Phenomenological Analysis of Disaster-Related Experiences in Fire and Emergency Medical Services Personnel

Abstract This article explores the experiences of fire and Emergency Medical Services (EMS) personnel during and immediately after a technological event using a phenomenological approach. Personnel engaged in the rescue operations during and immediately after the Ghislenghien gas explosion reflected upon their experiences in their responses to a specially designed, self-reporting questionnaire that included open-ended questions. Firefighters reported more perceived threat and direct exposure to death than did EMS personnel. Qualitative analysis indicates that the central characteristics of this potentially traumatizing event were the suddenness and massiveness of the impact, and the fact that it involved young victims and/or multiple deaths. With regard to emotions, powerlessness, horror, fear, a sense of apocalypse, and grief were experienced by both firefighters and EMS personnel. Firefighters noted that the death of colleagues, the involvement of friends and family, the massive impact, and exposure to the burned victims were most shocking. Emergency Medical Services personnel and in-hospital staff reported the impact, the confrontation with death, the involvement of friends and family, and the pain, suffering, and screaming of burned victims as the most shocking aspects of this event. Qualitative differences in the lived experiences of firefighters, EMS personnel, and in-hospital staff might be explained by differences in life threat, contact with death, and various degrees of training. De Soir E, Knarren M, Zech E, Mylle J, Kleber R, Van der Hart O. A phenomenological analysis of disaster-related experiences in fire and Emergency Medical Services personnel. Prehosp Disaster Med. 2012;27(2):1-8.