SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
The role of the state in the entrepreneurship ecosystem: insights from Germany

The performance of new ventures is strongly impacted by something much larger than the business itself: the surrounding ecosystem. In this network of actors, the role of the state has been underestimated up to this point. This article investigates the nature and composition of the German entrepreneurship ecosystem and suggests a new framework for assessing the role of the state in the entrepreneurial ecosystem. This framework is applied using data from a meta-analysis of existing research as well as qualitative interviews to assess the government influence on the different phases of the science-based innovation process. By analyzing different public initiatives in Germany, this paper provides insights into how governments can influence the attractiveness of an ecosystem, but it also highlights various improvement opportunities. Germany already features a dynamic entrepreneurship ecosystem and has a distinct political agenda to promote entrepreneurship. Improvements have been made in the regulatory environment and in entrepreneurship education, especially tertiary education, and publicly funded programs support the early stages of new ventures. The incentive schemes for scientific staff should be aligned to encourage more tech transfer activities, and more later stage financing is needed, through the involvement of private investments, in order to exploit the full growth potential of new ventures. Germany also needs policies that affect social values and attitudes towards entrepreneurship in order to reduce the stigma of failure and enhance the appreciation of entrepreneurial activity in the society.
Preparation of Superfine Aluminum Hydroxide Fine Powder by Spontaneous Nucleation

Superfine aluminum hydroxide fine powder with sheet-like particle in the range of dozens of nanometers to a few micrometers were prepared in high yields(90%) by spontaneous nucleation which is decompose under 45°C after cooling and diluting the solution of NaAlO 2 abruptly without seeding .The influence of the concentration of NaOH when decomposing on the distribution of particle size were investigated .The vacuum freezing drying oven with vacuum(11pa) and freezing(-45°C) were used .The study showed that the optimum is under the concentration of 2.69 mol/kg.Moreover,the powders dried by the vacuum freezing drying oven has no agglomerative phenomenon and the particle size are much smaller then other ovens.
Management of hematocolpos in adolescents with transverse vaginal septum

The aim of this study was to underline the significance of premenarcheal gynecological examination in patients with transverse vaginal septum that could possibly be complicated with endometriosis.Retrospective study including the period between January 2008 and December 2010.Second Department of Obstetrics and Gynecology.We searched our databases regarding cases of hematocolpos caused by transverse vaginal septum.Among the patients presented with hematocolpos we identified 4 cases caused by transverse vaginal septum.We present the management of these cases regarding diagnosis, differential diagnosis, and treatment. The mean age of the patients was 13.1 years. All patients presented in our department with hypogastric abdominal pain and hematocolpos. No problems in adrenarche or thelarche were mentioned. The U/S and MRI revealed a normal cystic in the upper part of the vagina--hematocolpos varying from 42 × 26 × 30 to 73 × 55 × 32 mm. Three of the patients had an upper transverse vaginal septum while one had a middle transverse vaginal septum. Only one patient had a concomitant anomaly of the urinary system (ectopic kidney). In our patients, after laparoscopic examination 3 out of 4 patients had findings of endometriosis (2/3 with stage I-minimal endometriosis and 1/3 with stage II-mild endometriosis).Physicians should be aware of transverse vaginal septum in the differential diagnosis of hematocolpos with abdominal pain and primary amenorrhea in the early adolescent years. Early diagnosis could be based on premenarcheal gynecological examination and could lead to correct management in order to avoid the complications of endometriosis (dysmenorrhea or infertility).
Enhanced Network Throughput of Wireless Network for Digital Video Transmission

Digital video transmission using wireless technology is an important functionality in multimedia communication. Such wireless transmission considers various parameters of channel like reliability, quality of service (QoS), transmission rate, transmission delay etc. User datagram protocol (UDP) is a fast transmission protocol used by most of the real-time applications as it is suitable for delay sensitive applications like video and audio transmission. UDP does not provide flow control or error recovery and does not require connection management. Since more applications with real-time constraints are introduced day by day, both over wired and over wireless, some improvements should be made in order to obtain better end to end performance. This paper surveys the literature on real time communication over wireless and suggests an intermediate solution providing more reliability in transmission using adaptive error control mechanism. The idea used is to inject an adaptive amount of redundant packets (RPs) in every sent block (or datagram) in order to achieve a desired recovery rate at the receiver without using any retransmission mechanism. The technique used is called adaptive forward error control (AFEC) and is implemented at physical layer. The network simulator NS-2 is used to evaluate AFEC and the simulation results indicate that the suggested methods can guarantee enhanced network throughput for video transmission in the high packet loss wireless network.
Aquabuddy-Care: a groundbreaking solution for elderly and disabled people with reduced mobility that finally enables caregivers to effectively and safely bathe/shower them in their own beds.

The progressive ageing of the population is becoming a major problem for society, who sees how ageing comes accompanied by crucial challenges that constraint our healthcare systems. Dependency is one of these challenges, adopting today the form of over 3 million Europeans unable to live independently due to ageing, disease, accidents or long term disability. These individuals rely and depend on caregivers to accomplish daily activities, being hygiene one of the most critical steps. Fulfilling hygiene tasks becomes specially challenging and time-consuming for the saturated personnel at hospitals, clinics or elderly homes, who need to be extra careful with these patients at higher risk of infection. The complexity of the current processes to wash or bathe bedbound patients (which involves transferring the patient out of bed) enters in conflict with the workload pressure faced by caregivers (which limits the time available for each patient). In response, we have developed and validated Aquabuddy-CARE (AQB), a miniaturized and portable shower system that enables patients to undertake hygiene tasks in bed, rapidly and in a dignified manner. The combination of advanced materials, sustainable production process and proprietary water flow system guarantees the efficiency of the technology concerning water consumption and prevention of contamination. After completing the validation at the pilot scale, this project aims to finalise the industrialization and field-testing of AQB. The Feasibility Study planned in Phase 1 will help us secure the project from all technical, financial and commercial standpoints. Once in the market, AQB will bring significant benefits for caregivers and patients worldwide, helping to alleviate the raising impact of ageing and disability while improving their life quality. In turn, AQB will boost our growth, expecting to hire 12 new people in 5 years, gain €11.2 million in profits and reach a ROI of 4.6 per euro invested in the project.
Mechanisms independent of abscisic acid (ABA) or proline feedback have a predominant role in transcriptional regulation of proline metabolism during low water potential and stress recovery

Proline accumulation in response to abiotic stress is controlled partially by transcriptional regulation of key enzymes including Δ¹-pyrroline-carboxylate synthetase1 (P5CS1), proline dehydrogenase (ProDH), ornithine amino transferase (OAT) and Δ¹-pyrroline-carboxylate dehydrogenase (P5CDH). For these genes, the role of abscisic acid (ABA), role of feedback regulation by high proline and the mechanisms of gene regulation upon stress release remain unclear. An ABA-deficient (aba2-1) mutant, mutants deficient in proline accumulation (p5cs1), as well as double mutants deficient in both, were used to determine the importance of these factors in transcriptional regulation of proline metabolism. Upregulation of P5CS1 by low water potential was less dependent on ABA than that of stress-marker genes used for comparison. ProDH downregulation by low water potential and upregulation by stress release was not impaired in aba2-1, p5cs1 or p5cs1/aba2-1 compared with wild type despite differing ABA and proline levels in these mutants. Thus, ProDH is a model for characterization of novel regulatory mechanisms associated with low water potential and stress recovery. Both OAT and P5CDH were upregulated during low water potential. This contrasts with previous salt stress experiments and raises questions about the flux of metabolites through proline metabolism under low water potential when high levels of proline accumulate.
Online deposition over oceans: modeling the effect of air pollution on ocean bio-geochemistryin an earth system model

Iron (Fe) deposition from dust and combustion aerosols is essential for the marine primary productivity in large portions of the world ocean, where phytoplankton growth mitigates part of the anthropogenic CO2 emissions. Under polluted conditions, the atmospheric acidity and organic ligands dramatically enhance aerosol Fe-mobilization, perturbing also the marine CO2 uptake capacity upon aerosol Fe deposition. Air-quality regulations, designed to decrease future atmospheric pollution, will consequently moderate the dissolved Fe deposition flux over oceans and change its pattern. However, the effect of air pollution on the bioavailable Fe supply into the oceans and their primary productivity remains largely ambiguous, with a likely but poorly known climatic impact. The ODEON project will address this long-standing research question by performing for the first time coupled atmosphere-ocean-climate simulations with the European Earth System Model (ESM) EC-Earth, focused on the impacts of Fe deposition on the oceanic carbon-cycle. Recently, important advances were made by the applicant in understanding aerosol Fe dissolution and emission processes. However, ESMs still use simplified parameterizations and asynchronous coupling of Fe supply to the marine biogeochemistry, inserting severe uncertainties in the response of the carbon-cycle to anthropogenic emissions. ODEON aims to improve this situation by developing modelling tools beyond-state-of-the-art, to simulate the atmospheric Fe-cycle in EC-Earth coupled to the embedded ocean biogeochemistry model. The future fellow’s strong atmospheric chemistry modelling background, together with the advanced training-through-research plan on cutting-edge and multi-disciplinary EMS techniques, ensures the feasibility of this project. ODEON’s training scheme in climate modelling, ocean biogeochemistry and interaction with science-users will contribute to the applicant’s development as an independent and interdisciplinary researcher.
Segregation, Immigration, and Latino Participation in Ethnic Politics

This article examines the way in which racial/ethnic context influences Latino support for ethnic political causes. Welch et al. argue that feelings of solidarity within the African American community intensify as the size of the African American population in an individual’s residential environment increases. We extend this hypothesis to Latinos, while also considering how other scholars have hypothesized different structural patterns of residence among Latinos to influence their political behavior. We also consider how higher levels of in-group heterogeneity within the Latino community might complicate this relationship. These hypotheses are tested using data from the 1999 Harvard/ Kaiser/Washington Post National Survey of Latinos.We find that higher levels of segregation between Anglos and Latinos dampen the positive relationship between Latino group size and participation in ethnic political causes.
SOUNDSCAPES IN THE NORT ADRIATIC SEA AND THEIR IMPACT ON MARINE BIOLOGICAL RESOURCES

The Northern Adriatic Sea (NAS) is an area highly impacted by increasing maritime traffic, tourism and resource exploitation, whilst having a very vulnerable biodiversity. The main objective of the project is to create a cross-border technical, scientific and institutional cooperation to face together the challenge of assessing the impact of underwater environmental noise on the marine fauna and in general on the NAS ecosystem. This cooperation aims to ensure an efficient protection of marine biodiversity and to develop a sustainable use of marine and coastal ecosystems and resources. The objectives of the project are to be pursued in three ways: Implementing a shared monitoring network for a coordinated regional and transnational assessment of the underwater noise, evaluating the noise impact on marine biological resources, developing and implementing a planning tool for straightforward management.
Prediction Framework Integration into ERP Systems

This paper continues previous research that has been done in the direction of the Prediction Framework, also known as Autonomous Open Data Prediction Framework. Going through and highlights Open Data Business Model step-by-step procedures found in the literature. Afterward, Orchestrating Business Processes is represented with ERP Systems that Enables Standards for Enabling Business Level Modeling. The technologies such as Web Services, XML, SOAP, WSDL, BPEL, WSFL, XLANG, ORDS that are confrontation between those six methods in end representation is shown in the Integration Processes concept. Able to increase business value by increasing the efficiency of data availability between data sources and ERP systems. The objective is to develop an integration process concept that can be implemented into ERP systems within the prediction framework.
Applying voltage-imaging techniques to visualise the effect of lysergic acid diethylamide (lsd) on cortical layer v pyramidal cells and its adaptation during tolerance development

Serotonergic hallucinogens (sHG), such as lysergic acid diethylamide (LSD), rank among the most controversially discussed agents of modern neuropsychopharmacology. They are popular drugs of abuse, scientifically are used to study the pathophysiology of psychosis, can pose a threat to health, but most recently also re-gained attention as promotors of psychotherapy. The controversy at hand remains unresolved by modern science and politics, and the European Research Area is faced with the imminent challenge to come up with a strong and competitive scientific basis that is able to elucidate how these drugs work and how their working potentially translates into benefit and/or detriment to European health and society. 
The psychoactive effects of sHG are mediated by activation of serotonin 2A (5-HT2A) receptors within the cortex of the brain. In vivo, sHG disconnect cortical networks, desynchronise alpha oscillations and inhibit the metabolism of the cortex. In vitro, sHG primarily enhance the excitability of cortical layer V pyramidal cells (LVPCs), which is accounted for by 5-HT2A-glutamate interaction. The in vivo effects of sHG often are interpreted with regard to their in vitro effects. As there are virtually no LVPC specific investigations in living animals, however, the in vivo relevance of the postulated 5-HT2A-LVPC-glutamate triangle is highly speculative. 
Our project brings together Prof. Thomas Knöpfel, who has been pioneering optogenetic electrophysiology, and the 5-HT2A-hallucinogen expertise of Dipl. Psych. Tobias Buchborn. It applies advanced techniques of voltage imaging (with the voltage-sensitive fluorescent protein Butterfly 1.2 genetically targeted to LVPCs), combines them with selective neuropharmacological challenges and 5-HT2A specific ethological observations, and reveals within the brain of waking mice whether it is indeed LVPCs and their submissiveness to 5-HT2A-glutamate interaction that represent the point pivot of the cortical action of LSD.
A new paradigm for centromere biology:evolution and mechanism of cenh3-independent chromosome segregation in holocentric insects

Faithful chromosome segregation in all eukaryotes relies on centromeres, the chromosomal sites that recruit kinetochore proteins and mediate spindle attachment during cell division. Fundamental to centromere function is a histone H3 variant, CenH3, that initiates kinetochore assembly on centromeric DNA. CenH3 is conserved throughout most eukaryotes; its deletion is lethal in all organisms tested. These findings established the paradigm that CenH3 is an absolute requirement for centromere function. My recent findings undermined this paradigm of CenH3 essentiality. I showed that CenH3 was lost independently in four lineages of insects. These losses are concomitant with dramatic changes in their centromeric architecture, in which each lineage independently transitioned from monocentromeres (where microtubules attach to a single chromosomal region) to holocentromeres (where microtubules attach along the entire length of the chromosome). Here, I aim to characterize this unique CenH3-deficient chromosome segregation pathway. Using proteomic and genomic approaches in lepidopteran cell lines, I will determine the mechanism of CenH3-independent kinetochore assembly that led to the establishment of their holocentric architecture. Using comparative genomic approaches, I will determine whether this kinetochore assembly pathway has recurrently evolved over the course of 400 million years of evolution and its impact on the chromosome segregation machinery.
My discovery of CenH3 loss in holocentric insects establishes a new class of centromeres. My research will reveal how CenH3 that is essential in most other eukaryotes, could have become dispensable in holocentric insects. Since the evolution of this CenH3-independent chromosome segregation pathway is associated with the independent rises of holocentric architectures, my research will also provide the first insights into the transition from a monocentromere to a holocentromere.
Consequences of Debt Forgiveness: Strategic Default Contagion and Lender Learning

I use a unique data set of loans to small business owners to examine whether lenders face adverse consequences when they grant debt forgiveness to borrowers. I provide evidence consistent with borrowers communicating their debt forgiveness to other borrowers, who then more frequently strategically default on their own obligations. This strategic default contagion is economically large. When the lender doubles debt forgiveness, the default rate increases by 10.9% on average. Using an exogenous shock to the lender's forgiveness policy, my findings suggest that as the lender learns about the extent of borrower communication the lender tightens its debt forgiveness policy to mitigate default contagion.
A Critical Review on Regional Integration Processes in East Asia

The major economies of East Asia, namely Japan and the Four Asian Tigers, have always prioritized the WTO-led multilateral trade liberalization over other trade arrangements primarily due to their unique economic structure with a high dependency on the world’s major markets such as the US. Along the same line, even the huge blow from the Asian Financial Crisis in 1997 only managed to trigger a few initiatives to aide East Asian regional integration while being led by different centering bodies, APEC and ASEAN. These dispersed efforts naturally resulted in no realistically significant achievements in the light of ‘integration’ until the present day. Under these circumstances, East Asia now faces a second opportunity to achieve its economic independence from the extra-regional influences via regionalization: the 2009 Global Credit Crunch. This paper hereupon critically reviews the actual progress and the likely impacts of the current global recession on the East Asian region.
The Role of Atmospheric Transformations in Determining Environmental Impacts of Carbonaceous Nanoparticles

In studies that have explored the potential environmental impacts of manufactured nanomaterials, the atmosphere has largely been viewed as an inert setting that acts merely as a route for inhalation exposure. Manufactured nanomaterials will enter the atmosphere during production, use, and disposal, and rather than simply being transported, airborne nanoparticles are in fact subject to physical and chemical transformations that could modify their fate, transport, bioavailability, and toxicity once they deposit to aqueous and terrestrial ecosystems. The objective of this paper is to review the factors affecting carbonaceous nanomaterials' behavior in the environment and to show that atmospheric transformations, often overlooked, have the potential to alter nanoparticles' physical and chemical properties and thus influence their environmental fate and impact. Atmospheric processing of naturally occurring and incidental nanoparticles takes place through coagulation, condensation, and oxidation; these phenomena are expected to affect manufactured nanoparticles as well. It is likely that carbonaceous nanomaterials in the atmosphere will be oxidized, effectively functionalizing them. By influencing size, shape, and surface chemistry, atmospheric transformations have the potential to affect a variety of nanoparticle-environment interactions, including solubility, interaction with natural surfactants, deposition to porous media, and ecotoxicity. Potential directions for future research are suggested to address the current lack of information surrounding atmospheric transformations of engineered nanomaterials.