SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
PAPER COMPRISING FIBRILLATED SYNTHETIC FIBRES

The present invention relates to a paper, comprising: - fibrillated synthetic fibres; and - non-fibrillated synthetic fibres.
Dissecting quantitative traits and their underlying genetic interactions via systematic genome editing

Despite the ubiquity of genome sequence data, unravelling the contributions of genetic variation to phenotypic diversity remains one of the greatest challenges in genomics. This is partly due to our very limited knowledge of how multiple variations combine to create phenotypes. There is a clear need for a systematic, perturbation-based approach to study the phenotypic consequences of genetic variants in different genomic and environmental contexts. Previous efforts have primarily used loss-of-function or overexpression approaches, but it is known that subtle, naturally occurring variants have the most relevance for complex, quantitative traits. Our proposal aims to dissect these effects by systematically engineering and functionally profiling naturally occurring single-nucleotide variants (SNVs) and small insertion/deletion polymorphisms (indels) in the S. cerevisiae species in three diverse genetic backgrounds. To generate such an unprecedented collection, we will apply a high-throughput CRISPR approach that allows rapid isolation of sequence-verified strains. DNA barcodes integrated into the genome of each strain will enable pooled, competitive growth, which will reveal how variants modulate fitness as a function of environment and genetic background. We will test our collection for pairwise and higher order interactions, assay their impact on cellular processes and dissect pleiotropic roles of highly connected genes. Our work will circumvent the key limitations in current high-throughput genome editing screens and enable the largest interrogation of the functional impact of genetic variation in different environmental and genetic contexts to date. The combined insights and tools generated by our work will aid in developing predictive models of the effects of genetic variation within specific environmental and biological contexts, providing guiding principles for understanding the consequences of human genetic variation.
Ancient projectile weapons from ice patches in northwestern Canada: identification of resin and compound resin-ochre hafting adhesives

Abstract This article describes a study of adhesive residues on 16 projectile weapons, 15 from ice patches in southwest Yukon and one from the Selwyn Mountains, Northwest Territories. The objects selected for analysis cover much of the Holocene, with radiocarbon dates from 8103 to 170 cal. yr. BP and represent both throwing-dart and bow-and-arrow technology. The goal of the study was to identify the residues associated with hafting and to determine if patterns of material use exist. The residues were analyzed using a combination of analytical techniques: Fourier transform infrared spectroscopy (FTIR), gas chromatography–mass spectrometry (GC–MS), Raman spectroscopy, scanning electron microscopy–energy dispersive spectrometry (SEM–EDS) and polarized light microscopy (PLM). Hafting adhesive residues were found on nine objects that relate to throwing-dart technology and on two objects related to bow-and-arrow technology. In all cases where adhesive was found, the projectiles included chipped stone components. All adhesives, regardless of age, were found to be conifer resin, more specifically identified as spruce ( Picea sp.). While the majority of adhesives were relatively pure, homogeneous spruce resin, in the case of three stone dart points, the spruce resin was intentionally mixed with red ochre to produce a compound adhesive. A fourth stone dart point showed the use of spruce “callus” resin, a type of resin produced during wound closure on the surface of the tree, which has a unique chemical signature.
Exploring social permeability in ancient communities of europe

The Ex-SPACE project aims to explore trends in social permeability in some ancient communities of Europe, focussing on scientific analysis of a selection of Italian pre-protohistoric burial contexts. The ‘social permeability’ of a group refers to its capacity to incorporate non-locals. What this research seeks to understand is how this pattern changes across time, space and social groups, and how it articulates with the radical socio-cultural transformations that arose during the second half of the 3rd millennium BC up to the late 2nd millennium BC. Italy represents one of the archaeologically richest regions of Europe, in terms of number of sites, their visibility across the landscape and the quantity of materials preserved in museums. In addition, as repeatedly highlighted in the archaeological literature, northern Italy was a cultural crossroads between Central Europe and the Mediterranean world, if not also a target of invasions. The scientific challenge of this research is to identify non-local individuals among mortuary contexts and to understand the impact that these allogeneic components had on the socio-economic development of communities, in the wider context of demographic change from Late Copper Age unstable village communities to Late Bronze Age proto-urban centres.
The Research of Multipath and Linear Error for Pseudolites Applications

Pseudolites are ground-based transmitters that send global navigation satellite system like signals, such as GPS, GLONASS, or Galileo. As an independent system for indoor positioning, pseudolites technique can be explored for a wide range of positioning and navigation application where the signal of satellite GNSS can’t be received. However, with indoor environment, the positioning method of pseudolite navigation system is not entirely same as GNSS, and there are some challenging issues in research and system design. In this paper, a signal difference carrier phase measurement system with pseudolites is design. Furthermore, two major problems are studied that they are multipath error and linear errors.
Fostering dihs for embedding interoperability in cyber-physical systems of european smes

The initiative for Fostering DIHs for Embedding Interoperability in Cyber-Physical Systems of European SMEs (DIH4CPS) will help European enterprises overcome these innovation hurdles and establish Europe as a world leading innovator of the Fourth Industrial Revolution. DIH4CPS will create an embracing, interdisciplinary network of DIHs and solution providers, focussed on cyber-physical and embedded systems, interweaving knowledge and technologies from different domains, and connecting regional clusters with the pan-European expert pool of DIHs. Backed by the IVLab, an experienced and well-established network organisation focussed on Interoperability, DIH4CPS can innately build on an extensive existing network, add value to its existing knowledge transfer capabilities and guarantee the sustainability of the growing DIH network. DIH4CPS expands the already existing network and aims for creating an integrated platform for DIHs from different, especially digitally underdeveloped sectors and regions. A selection of eleven initially starting application experiments guarantees an outstanding funding for European SMEs and Mid-Caps right from the start and demonstrates the high dedication of the consortium to reduce the digital divide. At least ten additional experiments will take up that torch during the project and allow external companies from sectors in need to further exploit the DIH4CPS network and uplift their portfolio, especially by including (semi)-autonomy into their products and systems. DIH4CPS will not only benefit the application experiments but also the individual DIHs by significantly complementing the regional investments made. Implemented in the IVLab structure, the DIH4CPS Network will leverage and sustain its impact far beyond the project duration, creating a vibrant, overarching and cross sector one-stop-shop for collaboration between SMEs, DIHs and Tech providers.
Discussion on the Function of Management Efficiency

The 21st century is the century of management.The management efficiency of a country,an organization,each individual will determine the strength of its development and the level of competition.Analysis from the perspective of management philosophy,management efficiency features mainly the following four points.Management efficiency is an indicator of human practical ability.The essence of management is practice,the effectiveness of practice is synonymous with the efficiency of management.Management efficiency is helpful to improve the sense of competition.Seeking competitive advantage by efficient management practices can give a person with great power and pressure.Workers and managers in the ongoing competition not only improve personal productivity,but also improve the efficiency of social activities.Management efficiency optimizes resource allocation.Within a certain range,there are limited and fixed resources which can be used for management.The fundamental objective of society or organization performance management is to make the full use of scarce resources.Management efficiency boosts economic and social development.Management is increasingly becoming the fourth elements of the production practice.The functions of plan,organization,coordination and control in management can consolidate producers,production object and means of production,which produce good economic and social benefits.
TAX CREDIT — CAUSE THEM GIANLUCA

THE LG EXPRESS CAUSES THEM GIANLUCA OPERATES IN THE SECTOR OF VENDING COFFEE AND DRINKS AND RELATED PACKAGED FOODS. THE PRESENT INTERVENTION INTENDS TO
Predicting routes of tumour evolution driven by unstable genomes and selection

Despite progress in cancer drug development, the majority of patients who present with advanced, metastatic, solid tumours have incurable disease due to underlying cancer genomic diversity that provides a substrate for evolution and selection of drug resistance. The aim of this proposal is to describe, synthesise and model the micro- and macroevolutionary patterns of genomic instability underpinning the evolutionary dynamics of tumour life histories, to improve patient stratification, treatment and survival outcomes. Longitudinal clinical studies such as TRACERx are highlighting the complex processes that generate this intra-tumour heterogeneity (ITH). Genome Instability (GIN) describes aberrant changes within the genome, encompassing genome doubling (GD), numerical or structural chromosomal instability (CIN), and elevated DNA sequence mutational diversity. TRACERx has revealed that elevated DNA copy-number ITH rather than DNA sequence diversity is associated with increased risk of recurrence or death in non-small cell lung cancer (NSCLC). Why macroevolutionary CIN rather than somatic mutational diversity is associated with poor outcome remains unclear. Current animal models of NSCLC do not sufficiently model the multiple distinct patterns of GIN operating in patients. We aim to develop mouse lung cancer models that recapitulate the patterns of GIN observed in NSCLC patients. Using tumour barcode sequencing, a sensitive method of quantifying cellular fitness and individual tumour growth, we will investigate the effects of targeted-, chemo- and immuno-therapy on the newly generated GIN models. We will decipher if distinct patterns of GIN increase metastatic potential and treatment failure, and test if high mutational burden or high CIN increases the frequency of GD in cancer. Finally, we aim to investigate the effects of GIN upon immune surveillance, immune evasion, immunotherapy response, and the interactions between tumours and the tumour microenvironment.
Feel as Agent

Children suffering with learning and developmental disorders require daily training to develop their social skills. However, such daily training is sometimes not provided because it requires interactive help from therapists, and lots of special programs required for the training. We proposed an immersive digital dollhouse that enhances traditional psychological play therapy with sensors installed, while provides feedback from the sensors to the computer graphics (CG). The immersive digital dollhouse provides an immersive space for children, which develops their communication skills through their imaginary play with the complement of CG for enhancing the understanding of their situation, and it is easy to use in their home as daily training. We conducted an experiment with a 6-year old child with a similar level as the older children with developmental disorders. We found that the number of reactions was twice as many as with a normal dollhouse, and the number of miscommunications was less than one-tenth.
Single-Cell temporal tracking of epigenetic dna marks

Over the past decade, epigenetic phenomena have taken centre stage in our understanding of gene regulation, cellular differentiation and human disease. DNA methylation is a prevalent epigenetic modification in mammals, which is brought about by enzymatic transfer of methyl groups from the S-adenosylmethionine (SAM) cofactor by three known DNA methyltransferases (DNMTs). The most dramatic epigenomic reprogramming in mammalian development occurs after fertilization, whereby a global loss of DNA methylation is followed by massive reinstatement of new methylation patterns, different for each cell type. Although DNA methylation has been extensively investigated, key mechanistic aspects of these fascinating events remain obscure. The goal of this proposal is to bridge the gap in our understanding of how the genomic methylation patterns are established and how they govern cell plasticity and variability during differentiation and development. These questions could only be answered by precise determination of where and when methylation marks are deposited by the individual DNMTs, and how these methylation marks affect gene expression. To achieve this ambitious goal, we will metabolically engineer mouse cells to permit SAM analog-based chemical pulse-tagging of their methylation sites in vivo. We will then advance profiling of DNA modifications to the single cell level via innovative integration of microdroplet-based barcoding, precise genomic mapping and super-resolution imaging. Using this unique experimental system we will determine, with unprecedented detail and throughput, the dynamics and variability of DNA methylation and gene expression patterns during differentiation of mouse embryonic cells to neural and other lineages. This project will give a comprehensive, time-resolved view of the roles that the DNMTs play in mammalian development, which will open new horizons in epigenomic research and will advance our understanding of human development and disease.
Ict powered machining software suite

The advances in the Information and Communication Technologies are revolutionizing our everyday life. However, the manufacturing industry does not yet take complete advantage of this huge potential. Using the latest ICT developments, MC-SUITE project wants to boost the productivity of manufacturing industry. On the one hand, machining process modelling empowered by High Performance Computing technologies allows simulating precisely the cutting process including force and surface quality. On the other hand, monitoring of the machine empowered by Big Data and Cloud technologies allows analysing the real process including vibration and process instability issues. Bridging the gap between virtual and real worlds, correlations of the simulated and monitored cutting process will allow optimizing both simulation and machining performances.
In agreement with the work programme, the combination of manufacturing technologies and ICT is at the core of the construction of this consortium. The project will complement science with innovation to propose new software frameworks which can collect information from multi-monitoring devices as turnkey technologies to improve the machining process. MC-SUITE will produce multiple impacts in the European industry, reflecting the trans-disciplinary nature of the project. The participation of industrial partners, both SMEs and large companies from ICT and industrial sectors, will ensure that the project will directly impact on wide range of industries such as metal part manufacturing, Computer-Aided Manufacturing software, machine tool industry. MC-SUITE project has the opportunity to produce a new breakthrough in the productivity of the European manufacturing industry.
Gringos, nômades, pretos – políticas do musicar africano em São Paulo

Ao acompanhar nos últimos anos músicos africanos recém-chegados ao Brasil, observamos como seu musicar em São Paulo cria um mundo de imaginação e potencialidade política, um espaço para a solidariedade, habitado por entidades africanas e afrodiaspóricas da história passada e presente, de lutas e manifestações artísticas anticoloniais, antiescravistas ou afropolitanas (Mbembe, 2015). Como estes músicos lidam com as políticas raciais e culturais do país? Como o racismo e os movimentos afro-brasileiros os interpelam? Que capitais transculturais (Glick-Schiller e Meinhof, 2011) ou formas de “ação social” (Blacking, 1995) mobilizam para navegar na cena artística brasileira? Como lidam com as instituições culturais e com os movimentos sociais? Ser africano no Brasil - seja no palco, no estúdio de gravação, em eventos artivistas ou solidários - é sempre um ato de resistência. “Gringos” ou “nômades” estes artistas constituem uma “comunidade musical” (Shelemay, 2011) com quem dialogamos num fazer etnográfico fílmico e compartilhado.
METHOD OF MAINTAINING INKJET PRINTHEAD MENISCUS

A container component decorating system has a decorating station (156), a container component handling module (102), a supply of colored inks, and inkjet printheads (124). The decorating station (156) delivers art graphics to container components (14) in a manufacturing queue (22). The inkjet printheads (124) comprise nozzles through which the colored inks are delivered. A flush cycle controller activated a flush cycle of the nozzles to deposit a flush cycle ink pattern (109) on a substrate to restore a meniscus (110) on the nozzles.
Human action recognition using modified slow feature analysis and multiple kernel learning

A novel human action recognition method is proposed, which includes two periods of action feature extraction and action recognition. Firstly, we use a modified slow feature analysis (SFA) to extract video local feature. Unlike slow feature analysis, we redefine the objective function with supervised information, which make the modified SFA more suitable to preserve the slow feature and label information. Meanwhile, in effort to cope with the dimension explosion in SFA, locality preserving projections (LPP) is used to reduce the quadratic expansion dimension. Secondly, we use a multiple kernel learning method (MKL) to classify human action, in which the weights of different kernels are optimized by combining Bacterial Chemotaxis method and Powell method. The results of experiments indicate the efficiency of our method.
Improving the enabling environment and public awareness for innovation in the South-East-European food sector through transnational collaboration

Project aims at building the capacity of institutions supporting innovation in the food sector and promoting public awareness on benefits of innovation, making the sectoral innovation easier through transnational cooperation of the national food technology platforms and related institutions. Although food industry has specific importance in SEE economies, the level of innovation in the region is not satisfactory, partly due to the non-favourable environment and the lack of society's support. Barriers of innovation will be exploited by focus groups with institutions in 9 countries. Capacity building tools for improving governance (national innovation strategies, operating industry innovation panels, best practice guides, ICT solutions) and tools for increasing public awareness (communication campaigns, virtual forums) will be developed for the support institutions. Train the trainers courses on food chain management, using ICT based solutions in the food sector and knowledge transfer will be provided for the key staff and a service manual developed for innovation supporting services. Study tours will be organised mainly for non-EU participants. Tools will be implemented. A SEE forum will be established for transnational collaboration, which is intended to be maintained after the end of the project. Transnational collaboration will enhance innovation in SEE by exchange of experience, integration of knowledge.
MAGICAL WAND AND INTERACTIVE PLAY EXPERIENCE

The invention provides a unique interactive play experience carried out utilizing a toy "wand" 100 and/or other actuation/tracking device. In one embodiment the wand 100 incorporates a wireless transmitter and motion-sensitive circuitry adapted to actuate the transmitter in response to particular learned wand motions. The wand 100 allows play participants to electronically and "magically" interact with their surrounding play environment simply by pointing, touching and/or using their wands 100 in a particular manner to achieve desired goals or produce desired effects. Various wireless receivers or actuators are distributed throughout the play facility to support such wireless interaction and to facilitate full immersion in a fantasy experience in which participants can enjoy the realistic illusion of practicing, performing and mastering "real" magic.
What's Up?

ABSTRACT This research examines the effect of the vertical positioning and format of online advertising on attention, aided recall, and brand attitude. Prior research (Previc, 1990) suggests greater attention for stimuli in the lower visual field (LVF) than in the upper visual field (UVF). The results of this online study indicate that (1) lower page placement significantly increases ad attention, supporting prior LVF/UVF research; (2) there is an inverse relationship between ad attention and brand attitude (in this study9s online environment), supporting mere exposure theory; and (3) online ad format (rectangle ad or leaderboard) has a significant direct effect on attention, aided recall, and brand attitude, attributed to object salience/familiarity. Management implications are discussed.
Morphological Evidence for Hybridization in the Sister SpeciesMyotis myotisandMyotis oxygnathus(Chiroptera: Vespertilionidae) in the Carpathian Basin

A recent molecular-based study suggested that two sister species of mouse-eared bats (Myotis myotis and M. oxygnathus) share some mtDNA haplotypes when they occur in sympatry. We used traditional morphometric methods in order to find potential hybrid specimens. Multivariate morphometric analysis of 22 cranial and dental characters was applied to a sample of 298 adult specimens of mouse-eared bats (Myotis myotis and M. oxygnathus) from their sympatric range in the Carpathian Basin. Additionally, we included several juvenile exemplars of both species in order to exclude the treatment of juvenile specimens as individuals with intermediate characteristics. Principal Component Analyses (PCA) and Discriminant Function Analysis (DFA) revealed a distinct separation between specimens of M. myotis and M. oxygnathus, with 6 specimens in an intermediate position. All intermediate specimens come from the contact area of M. myotis and M. oxygnathus. A subsequent detailed analysis showed that intermediate specimens are similar to M. myotis in skull and mandible size, but with tooth-row size similar to M. oxygnathus. An analogous situation has been described in several species of small mammals. Bats designated as intermediate are probable hybrids, i.e. their phenotypes lay between the parental forms.