SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Laser-Assisted surgical system to revolutionize cardiac bypass surgeries

Coronary Artery Bypass (CAB) surgery is performed annually in >700,000 patients to treat coronary artery disease and
prevent myocardial infarction (heart attack). Standard CAB surgery involves a highly invasive open-heart procedure in
arrested/non-beating heart, that is associated with long recovery times and severe complications. The surgeons are seeking
for less invasive, closed chest CAB procedures on beating heart, but current solutions are technically extremely challenging and thereby
only used in <1-3% of all surgeries. The vision of the SAFE-CAB consortium is to make the minimally invasive CAB
surgeries available to all surgeons as a novel standard of care, thereby substantially improve patient outcomes and reduce
health care costs. The goal of the project is to bring to market a first-of-its-kind laser-assisted minimally invasive surgical
system (surgical kit containing surgical implant and laser catheter). SAFE-CAB enables minimally invasive procedure on
beating heart, without the need for arresting blood flow or complex hand suturing. With shorter recovery times, less
complications and improved survival rates in high-risk patients, the SAFE-CAB technology has a potential to replace high-risk
open-heart surgeries. Replacing only 15% of open-heart surgeries in Europe and US translates to annual
market opportunity of >€89M and >€192M. Dutch SME AMT Medical has developed the proprietary SAFE-CAB
technology to clinical readiness. To substantially accelerate the market entry of the product, the company partners with a leading European cardiac surgery hospital Deutsches Herzzentrum Berlin and a pan-European clinical/regulatory medical device company HEMEX to
obtain regulatory approval through final clinical validation . To realize European wide-implementation, the consortium is complemented by a surgery training company LifeTec Group and the oldest professional organisation for cardiac surgeons European Society of CardioVascular and Endovascular Surgery.
METHOD AND DEVICE FOR DAMPING A ROLL HOUSING

The invention relates to a method and device for damping a roll housing for reducing sensitivity to vibrations. According to the inventive method, the damping ensues by means of a vibrating mass (8) situated above each post (2) forming the roll housing (1), and the vibrational energy is dissipated in a cushion (83) of an incompressible fluid constituting a direct link between each post (2) and the vibrating mass (8). According to the invention, the fluid cushion is maintained with permanent circulation by supply means (91) and by evacuation means (92) of an adjustable caliber. The frequency response of the system and its damping coefficient are set by the dimensioning of the vibrating mass (8), the controlling of the thickness (h) of the fluid cushion and its flow-rate through the calibrated orifice (92).
Anti-Diabetes Therapy: Safety Considerations for Patients With Impaired Kidney Function

The presence of type 2 diabetes mellitus (T2DM) is a common risk factor for the development of chronic kidney disease, but appropriate glycemic control can slow the progression of kidney dysfunction in patients with T2DM. The kidney plays a role in insulin resistance and gluconeogenesis, therefore, impaired kidney function alters glucose dynamics compared with normal kidney function, thus affecting antihyperglycemic treatment strategies. Glycemic management is further complicated by reduced drug clearance and a greater risk of hypoglycemia with use of certain medications, notably the sulfonylureas. Of the classes of antihyperglycemic drugs discussed in this review, caution is advised when using some classes in patients with T2DM and kidney disease.
HEART IN MOTION

"This project is part of the plan COEUR'ALP": “Hautes Vallées Mobilité – Coeur en Mouvement” aims to reduce individual car’s using and develop alternative of mobility, thorough new solutions of connection and information between territories and way of moving more respectful of environment. The aim is to introduce accessibility from outside and intermodally structured on territory yet with a more efficient and fluid intern mobility, more and more looked and dedicated to industries but also to inhabitants, workers and tourists. Therefore, from the sharing of territorial diagnostic and cross-border confrontations, partners will conjointly implement actions in favour of the establishment of more sustainable common transports, innovative transport services, organised car-sharing and the development of new way of transportation in bike or e-bike. Actions and Experimentations’ results will feed fluid mobility cross-border strategies diffusible and transferable.

The strategy aims to create conditions allowing to the cross-border area of High Valley to become an “intelligent destination” making territories reachable and attractive for inhabitants, tourists and for economic activities. The strategy recovers the territory of the Conference of High Valley (CHAV), cross-border association between local communities. CC of Guillestrois and of Queyras’s territories, which are part of CHAV, are not involve in this Plan due to their participation to Monviso’s PITER. CHAV’s representatives are nevertheless represented within the Instances of the Plan and accurate a full covering of the territory. Tourism is the key activity of this cross-border area; activity characterized by a high frequency in winter season and a polarisation on some towns (ski stations especially). The objective of this strategy is to preserve this attractivity and to reduce disparities within the area acting on four levers in capacity to answer to these common priorities identified problematics: 
- Create conditions allowing industries to identify new opportunities thorough innovation, enforce their competitiveness;
- Make a safest and resilient cross-border territory, thanks to attenuation measures of natural risks and actions of consciousness-raising and prevention; 
- Develop alternative to transports, thorough promotion of sustainable mobility and reduction of private vehicle use;
- Creare conditions to offer to mountains population from the territory social and health services in adequation, thorough actions of social innovation. 
This partnership includes public organisms and, for Italy, representatives from industries sphere.
Influence of Temperature on Alkaline Phosphatase Activity in Single Cells

We report a new approach for the determination of influence of temperature on enzymatic activity within a single fixed cell. We investigate enzyme activity at different temperature (22, 27, 32,37 and 42°C) by means of directed infrared laser heating. Our method generates individual cells at selected location, through the use of a flexible microfluidic delivery device and IR fiber heating system. Using timed exposure to the pore-forming agent digitonin, we successfully controlled the extent of poration within the plasma membrane of individual NG-108 cells. Mildly permeabilized cells (∼100 pores) were exposed to substrate concentrations for alkaline phosphotase and exposure to a series of temperature. We generated quantitative estimates for intracellular enzyme activity at different temperature at the single-cell level. This rapid approach offers a new methodology for characterizing influence of temperature on enzyme activity within single cells.View Large Image | View Hi-Res Image | Download PowerPoint Slide
CORE-HOLE DRILLING TOOL

A core-hole drilling tool is provided, comprising along with a tubular shank (2) also at least one extension (3), the wall thickness (D) and curvature of which correspond to those of the shank (2). Each of these extensions (3) is provided with a cutting insert (5). Since the width (B) of each of the cutting inserts (5) corresponds to the overall width of the annular surface area and this width is however only a few millimetres, the core-hole drilling tools according to the invention allow core-hole bores also to be introduced without any problem into workpieces of a material that has a hardness greater than 60 HRC.
Implementation of a circular economy based on recycled, reused and recovered indium, silicon and silver materials for photovoltaic and other applications

The main vision of CABRISS project is to develop a circular economy mainly for the photovoltaic, but also for electronic and glass industry. It will consist in the implementation of: (i) recycling technologies to recover In, Ag and Si for the sustainable PV technology and other applications; (ii) a solar cell processing roadmap, which will use Si waste for the high throughput, cost-effective manufacturing of hybrid Si based solar cells and will demonstrate the possibility for the re-usability and recyclability at the end of life of key PV materials. The developed Si solar cells will have the specificity to have a low environmental impact by the implementation of low carbon footprint technologies and as a consequence, the technology will present a low energy payback (about 1 year).
The originality of the project relates to the cross-sectorial approach associating together different sectors like the Powder Metallurgy (fabrication of Si powder based low cost substrate), the PV industry (innovative PV Cells) and the industry of recycling (hydrometallurgy and pyrometallurgy) with a common aim : make use of recycled waste materials (Si, In and Ag). CABRISS focuses mainly on a photovoltaic production value chain, thus demonstrating the cross-sectorial industrial symbiosis with closed-loop processes.
Temporal In-Situ Compression of Scientific Floating Point Data with t-GLATE

The need to cope with the huge amounts of data produced by today's HPC simulations has spurred the development of new lossy, error-bounded in-situ data compression methods. However, despite the time-continuous nature of HPC simulations, relatively few work has so far addressed temporal compression schemes. This article introduces t-GLATE, a compression algorithm designed for fast in-situ compression of time-dependent floating point data. t-GLATE compresses low-entropy exponents and high-entropy mantissas in two independent streams where mantissas are quantized according to a global look-up table. Temporal compression is achieved by storing the index differences rather than full look-up table indices for difference-frames. In experiments with our own implementations, several lossy in-situ compressors benefited from the inclusion of temporal compression schemes. We further compared t-GLATE to state-of-the-art compressors available as open source. In all test cases, t-GLATE compares favorably to other methods.
Shared mobility and Regional transport integrated PLAnning for a better connected Central Europe

Transport systems in Central Europe often show a lack of integration between modes of transport, resulting in weak local, regional and transnational accessibility. Disparities in appropriate connections within and among centres of urbanization often contribute to an unbalanced territorial development. While an emerging range of services in the so called “sharing economy” starts showing their benefits in urban and densely populated areas, their successful application on a regional scale including rural areas and other specific territorial contexts still has to be proven. SHAREPLACE aims at promoting, facilitating and enhancing the opportunities and capability of sharing and efficiently exploiting resources as a crucial factor for a sustainable and balanced territorial and socio-economic development. SHAREPLACE will develop an innovative approach for planning and delivering sustainable mobility services in CE, integrating conventional and flexible mobility services, as well as market-based and peer-to-peer sharing approaches in order to optimise and maximise the potential benefits for the transport networks, for all the groups of users and for the stakeholders. In particular, the project will target some specific outcomes: (i) Databases of services/offers, integrated timetables; (ii) Mobility community laboratories and workshops; (iii) Solutions for new sustainable shared services; (iv) a matching tool/platform for the implementation of shared services integrated with the main options offered by the local transport network; (v) mobility awareness initiatives. The project will be based on four pillars: (1) participation and collaborative approach; (2) technology as enabler; (3) sharing as the key to viable models for the provision of innovative services; (4) awareness and behavioural change as a catalyst. Transnational dissemination, communication and cooperation activities will ensure that the SHAREPLACE model is replicated and applied on a broader scale across CE.
Multi-Level Search Space Reduction Framework for Face Image Database

In face recognition, searching and retrieval of relevant images from a large database form a major task. Recognition time is greatly related to the dimensionality of the original data and the number of training samples. This demands the selection of discriminant features that produce similar results as the entire set and a reduced search space. To address this issue, a Multi-Level Search Space Reduction framework for large scale face image database is proposed. The proposed approach identifies discriminating features and groups face images sharing similar properties using feature-weighted Fuzzy C-Means approach. A hierarchical tree model is then constructed inside every cluster based on the discriminating features which enables a branch based selection, thereby reducing the search space. The proposed framework is tested on three benchmark and two self-created databases. The experimental results show that the proposed method achieved an average accuracy of 93% and an average search time reduction of 66% compared to existing approaches for search space reduction of face recognition.
On Exploitation Situation and Countermeasures Advice in the Development of Tight Gas in China

Tight gas, along with shale gas and coalbed methane, is known as top three unconventional gases. Tight gas development has strategically importance in the development of natural gas and energy structure adjustment in China. It should be considered in priority in the exploration and exploitation of unconventional gas. There are there key factors to develop tight gas: reliable data resources, mature technology, and overlapping with conventional natural gas. Making national development strategy, accelerating the progress of technology, deepening the reform of natural gas price and innovating regulatory system would speed development of tight gas. In future, tight gas will become the main growth of natural gas production. Keywords-tight gas; natural gas; countermeasures
Validation of precursor-m for enhanced cervical (pre)cancer detection

With an estimated 528,000 new cases and 266,000 deaths in 2012, cervical cancer (CC) is the fourth most common type of cancer in women, and the seventh overall. CC is preventable with regular screening tests and follow-up, and curable if found and treated early. In many countries, screening programmes for cervical cancer are in place, which have resulted in a marked decrease in cervical cancer incidence. hrHPV DNA testing will replace cytology as primary screening test for CC, but its drawback as stand-alone CC screening test is its low specificity, causing overdiagnosis and overtreatment. Triage of hrHPV+ women is essential to maintain a sustainable screening programme. 
PreCursor-M (Self-screen B.V.) is a proprietary molecular assay to determine disease progression and severity based on the methylation level of 3 host-biomarkers.  Supplementing hrHPV DNA screening with PreCursor-M will provide information on the presence of infection, and the response by the host cells. This will allow identification of all women at risk for cervical cancer without overdiagnosis and overtreatment.
The methylation level of three molecular markers (CADM1, MAL and miR124-2) was shown to increase proportional to cervical cancer progression and severity. In Precursor-M, these markers have been combined in a multiplex methylation marker panel. The markers have been separately validated in clinical settings, and the combined marker panel has been validated in laboratory and small-scale clinical settings. VALID-SCREEN will complete the final step towards commercial success for PreCursor-M: clinical validation of PreCursor-M in well-characterised cohorts, from five clinical centres, in four EU countries, as a triage test to hrHPV screening for cervical cancer.
FPGA Based Network Security architecture for High Speed Networks

Cryptography and Network Security in high speed networks demands for specialized hardware in order to match up with the network speed. These hardware modules are being realized using reconfigurable FPGA technology to support heavy computation. Our work is mainly based on designing an efficient architecture for a cryptographic module and a network intrusion detection system for a high speed network. All the designs are coded using VHDL and are synthesized using Xilinx ISE for verifying their functionality. Virtex II pro FPGA is chosen as the target device for realization of the proposed design. In the cryptographic module, International Data Encryption Algorithm (IDEA), a symmetric key block cipher is chosen as the algorithm for implementation. The design goal is to increase the data conversion rate i.e the throughput to a substantial value so that the design can be used as a cryptographic coprocessor in high speed network applications. We have proposed a new n bit multiplier in the design which generates less number of partial products less than n/2 and the operands are in diminished-one representation. The multiplication is based on Radix-8 Booth's recoding with different combinations of outer round and inner round pipelining approach and a substantial high throughput to area ratio is achieved. The Network Intrusion Detection System (NIDS) module is designed for scanning suspicious patterns in data packets incoming to the network. Scanning a data packet against multiple patterns in quick time is a highly computational intensive task. A string matching module is realized using a memory efficient multi hashing data structure called Bloom Filter, in which multiple patterns can be matched in a single clock cycle. A separate parallel hash module is also designed for eliminating the packets which are treated as false positives. The string matching module is coded and functionally verified using VHDL targeting Virtex II pro FPGA and performance evaluation is made in terms of speed and resource utilization.
Vacuum medical device for safe and gentle cervix grasping gynecological applications

For years, gynecologist practices related to Intra-Uterine Contraceptive Device (IUD) insertions, curettage and several other common indications, have featured poor care and low attention to female patients.
The use of the Tenaculum, grasping and pulling on the cervix, inside the vaginal cavity, proved to be painful and traumatic for 84% of the women, and eventually to trigger lesions and bleeding in 29% of the patients, as well as cross-contamination in 5-10% of the women. These disadvantages refrain the use of IUD contraceptive which exacerbates the unintended pregnancies, sized yearly in 85 mills and representing billions of euros in social costs worldwide.
In response, we have developed Aspivix, a new disruptive gynecological device that reduces the pain and eradicates the bleeding during the exploration procedure. Our patented device will replace the Tenaculum forceps, unchanged for over 100 years, to provide gynecologists an easy-to-use device where gentle and firm cervix uterus grasping and traction is needed. Thus, our device will facilitate the adoption of IUD, which could avoid up to 8% of unintended pregnancies and reduce derived social costs. Besides, Aspivix is intended for a single use which prevents the risk of contamination and cross-infection. Overall, Aspivix has the potential to shorten the intervention procedure (2 steps instead 7), which will represent for the physician a 28% economic benefit. As result, Aspivix will fulfill the needs of more than 64 M of women worldwide/year, a market that is projected to grow at a CAGR2016-2021 of ~6.5% due to the high demand of IUD insertions and is valued in more than €385M.
Poc in-office device for identifying individuals at high risk of osteoporosis and osteoporotic fracture

As a consequence of the ageing of the society, osteoporosis (literally “porous bone”) and its  complications is becoming more and more prevalent, making the bone disease a health priority in many parts of the world. Currently osteoporosis is commonly known as a “silent killer” disease. Usually osteoporosis manifests itself in a drastic manner, i.e. through fracture of the osteoporotic bone in the affected individual. Until now little or no measures for prevention or early detection of this disease are taken, because no simple, yet sufficiently precise or sensitive tools for early detection of individuals at risk of osteoporosis are available. The overall objective of the currently proposed PoCOsteo project therefore is the development, clinical validation and preparation for commercialisation of a Point-of-Care tool for bone disease (a.o. osteoporisis) prevention, detection and treatment. To realize this objective a balanced consortium of 5 research partners and 3 SME’s has been brought together, and a well considered workplan devised. Two TRL3 technologies for individual proteomic and genomic electrochemical sensors, available from 2 consortium partners will form the base of the developments. The sensors will be further optimised, combined in a single microfluidic cartridge and integrated in a complete and  independent point-of-care bone health assessment tool. The tool will consequently be clinically validated in 2 hospitals (Graz and Tehran), and a business plan for a commercial start-up company wil be prepared for the intended valorisation of the technical and medical activities. The aim is to reach a TRL6 / TRL7 for the complete tool and for the combined microfluidci cartridges. The project will be supported and advised by the IOF, the International Osteoporosis Foundation, which is the main global alliance of patient societies, research organizations, healthcare professionals and international companies working to promote bone, muscle and joint health.