SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Empirical approach for real-time estimation of air flow rates in a subway station

Abstract The EU-funded project called SEAM4US (Sustainable Energy mAnageMent for Underground Stations) is targeted to define advanced control systems for cost-effective management of subway stations, which will be applied to the pilot “Passeig de Gracia” station of the metro network in Barcelona (Spain). To this aim, the environmental conditions of the station must be monitored in real-time. In particular, this paper focuses on the challenge of air flows estimation because this is one of the most critical yet tough variables to be monitored: expensive and intrusive measurement methodologies cannot be used extensively. So a novel methodology, based on the use of ordinary measurement probes and analytical methods and capable of identifying in real-time the intensity and dynamics of ventilation that is taking place, will be suggested. The information deriving from real-time measurements and analyses will be used to dynamically adjust the mechanical ventilation burden, that is currently relying on the station’s air supply system, thanks to the adoption of intelligent control systems. Our study is based on both a measurement survey carried out in the aforementioned station and numeric analyses.
Text mining for occupant perspectives on the physical workplace

An analysis is presented of occupants' responses from a commercial building indoor environment satisfaction survey database. Building from satisfaction ratings and standardized categorical responses collected in surveys for 192 office buildings in the United States, text analysis software is used to analyse text responses to open-ended survey questions, focusing on occupants' perspectives on the workplace and building overall, temperature, and acoustics. These occupant texts detail interactions between occupants and their physical environment in a technical sense, but also interpret these interactions, assess their consequences, and reflect on social relationships and other matters that lie outside dimension-by-dimension assessments of the physical environment. Viewed together these texts reveal a user-centred perspective that points to issues that rest below the surface of more technical analyses of buildings, such as over air-conditioning, worker stress and frustration, workplace usability, and relation...
Bruno Vieira Amaral. <i>Integrado Marginal: Biografia de José Cardoso Pires</i>

Review of Vieira Amaral, B. (2021). Integrado Marginal: Biografia de José Cardoso Pires . Lisboa: Contraponto, 599 pp.
In vivo fuel utilization and metabolic regulation by brown adipose tissue

Brown adipose tissue (BAT) has a high capacity to dissipate chemical energy generated from glucose and lipids as heat, a process typically induced by cold exposure, termed thermogenesis. This process has gained significant clinical interest as a strategy against obesity and diabetes because of its potential to expend excess calories as heat. However, our understanding of BAT metabolism on an organismal level is still rudimentary, thus, to advance BAT-targeted therapies, we must first comprehensively define how BAT utilizes its key fuels, such as glucose in vivo.  
It is widely assumed that the major role of glucose during thermogenesis is to provide energy for the TCA cycle and subsequent uncoupling by the key thermogenic protein in BAT, uncoupling protein 1 (UCP1). However, recent literature reveal that this assumption is oversimplified since glucose has many fates once it enters cells, feeding into additional metabolic pathways beyond the TCA cycle, which are necessary for optimum thermogenesis.  
In this project, I will use state-of-the-art glucose-tracing technology that utilizes mass spectrometry, combined with classic Cre-Lox and novel CRISPR/Cas9 genome editing strategies to precisely define how thermogenic adipose tissue utilizes glucose in vivo and to delineate the role of solute carrier transporters of the SCL family, including SLC25a1, for glucose utilization and thermogenesis. SLC25a1 delivers the glucose-derived metabolite citrate across the mitochondrial membrane for use in de novo lipid synthesis, a process that are highly regulated in the BAT of cold exposed mice. 
This project will expand our understanding of how thermogenic adipocytes utilize glucose and will potentially reveal novel therapeutic strategies to enhance thermogenesis. My previous experience with BAT metabolism and mass spectrometry-based isotopic tracing combined with the technological tools of my outgoing host and my host institute ideally poises me to successfully achieve my goals.
Building the legal knowledge graph for smart compliance services in multilingual europe

European small and medium-sized enterprises (SMEs) and companies operating internationally face multiple difficulties to trade abroad and to localise their products and services in other countries. Complying with regulatory and legal aspects is crucial for these companies, who usually delegate the task to law and consultancy firms. These firms have to identify, retrieve and process documents from several sources, in multiple languages, and published by various institutions according to different criteria and formats. Such a burdensome task is hindering European SMEs to sell across borders, and thus reducing its competitive potential. Current content and data analytics solutions are mature to be transferred to the market and leverage the new opportunities created by the data linking paradigm and the open data movement.
Lynx aims to create a knowledge graph of legal and regulatory data towards compliance, in which heterogeneous data sources from different jurisdictions, languages and orders are aggregated and interlinked by a collection of advanced services. Building on this legal knowledge graph, a Lynx platform will offer compliance-related functionality focused on three specific business cases. In a first pilot, legal compliance solution for data protection will be offered, where data protection related documents are innovatively managed, analysed, and visualised across different jurisdictions. In the second pilot, the Lynx platform will help understanding regulatory regimes (norms and standards) related to operations in the Oil & Gas and Energy sectors.  The third pilot will provide a compliance solution in the labour law domain, where legal provisions, case law, administrative resolutions, and expert literature will be interlinked, analysed, and compared to define legal strategies in the context of legal practice. European citizens will also benefit from this solution because they will gain free access to a new collection of aggregated and interlinked legal data.
Maturation of plant autophagosomes: mapping the route to sustainability

Autophagy (from the Greek for “self eating”) is a catabolic process, by which eukaryotic cells degrade and recycle their content. This mechanism removes superfluous, damaged or harmful molecules or organelles and thus greatly impacts fitness of the organism. Autophagic cargo destined for degradation is delivered to the lytic compartment by specialized vesicles, autophagosomes. As of yet, the path from the plant autophagosomes assembly site to the lytic vacuole is uncharted territory. The first objective of this project is to perform a systematic study investigating the dynamic changes in morphology and biochemistry of the plant maturing autophagosomes and creating a molecular map of their route towards the lytic vacuole. This knowledge will be a fundamental contribution to the plant autophagy and plant membrane trafficking research fields. 
Autophagy is involved in regulating plant longevity, fecundity, stress tolerance and pathogen resistance. Unfortunately, our understanding of its role in establishing these traits is limited by the autophagy detection tools currently available. In this project I will establish the first high sensitivity luminescence-based non-invasive system for in planta detection of autophagic activity. This approach will be a break-through, as it will finally allow real-time in planta tracking of previously undetectable oscillations of autophagic activity throughout plant development under variable conditions.
During the past ten years I became an expert in plant autophagy research. My host, Prof. Schumacher, is a world renowned scholar in plant membrane trafficking and lytic vacuole biogenesis. Mutual exchange of our expertise will greatly benefit the project, expand our skills and broaden our scientific networks. Furthermore, this project is a very important step in my career development, as I will join a new field of studies, work in a new scientific environment with an outstanding reputation and markedly strengthen my line of research.
Rapid identification and discrimination of bacterial strains by laser induced breakdown spectroscopy and neural networks

A method based on laser induced breakdown spectroscopy (LIBS) and neural networks (NNs) has been developed and applied to the identification and discrimination of specific bacteria strains (Pseudomonas aeroginosa, Escherichia coli and Salmonella typhimurium). Instant identification of the samples is achieved using a spectral library, which was obtained by analysis using a single laser pulse of representative samples and treatment by neural networks. The samples used in this study were divided into three groups, which were prepared on three different days. The results obtained allow the identification of the bacteria tested with a certainty of over 95%, and show that only a difference between the bacteria can cause identification. Single-shot measurements were sufficient for clear identification of the bacterial strains studied. The method can be developed for automatic real time, fast, reliable and robust measurements and can be packaged in portable systems for non-specialist users.
Real-Time diagnostics for enabling advanced laser-based roll to roll materials processing

An experienced researcher with laboratory expertise in real time monitoring of laser-matter-ambient-interactions will be diversified towards scalable production which is desperately needed to fully realise the potential of high repetition rate, multi-kiloWatt, femtosecond and picoseconds laser technologies. The fabrication of integrated multifunctional thin film devices by additive (inkjet, spray) and subtractive (laser) manufacturing on Roll to Roll (R2R) production platforms is also suddenly possible and desperately needed to transform the competitiveness of Europe’s SME manufacturing sector. The training programme will lead to scalable innovation by developing diagnostics for ultra-precision laser processes.  The initial objective of the project is to identify which intersecting value chains for real time or in-line diagnostics can fully realise the potential of short pulse laser structuring.  Three diagnostics based on gated (i) spectral analysis of laser generated plasma plumes, (ii) image analysis of laser material ambient interactions and (iii) laser induced breakdown spectroscopy will be developed. The Fellow will demonstrate two process diagnostics using the R2R pilot line at the industry site. The application of these on-line tools will create pathways for cost effective production based on new nano-inspired materials relevant to flexible large area electronics. The multi-partner training environment provides excellent facilities for the talented ambitious Fellow. Over 30+ researchers will be directly impacted by the project. An active programme of knowledge transfer and information dissemination is also proposed based on industrial workshop, active conference participation, journal publications, and science promotion.
The Implementation of EU Environmental Policy in the Czech Republic: Problems with Post-Accession Compliance?

This article examines the implementation of EU environmental policy in the Czech Republic, focusing on the transposition and application of three key directives. It argues that, while the Czech Republic has had difficulty complying with EU environmental law since accession, overall its performance in this area does not conform to pessimistic scenarios of post-accession compliance. A key positive factor affecting the implementation of EU environmental policy in the Czech Republic, and a major reason for optimism about future Czech compliance with EU environmental law, is the active role of Czech environmental NGOs in the monitoring and enforcement of EU rules.
Transcriptional control of plasma cell development and function

Antibody-secreting cells consisting of short-lived proliferating plasmablasts and long-lived quiescent plasma cells are essential for the acute response to infection and long-term protection of the host against pathogens. Only a few regulators (Blimp1, IRF4, XBP1, Aiolos, Ikaros and E-proteins) have been implicated in the transcriptional control of antibody-secreting cells, and their target genes, with the exception of Blimp1 and E-proteins, are still unknown. This proposal aims to systematically identify key players in the development and function of antibody-secreting cells by using the CRISPR/Cas9 and Cre/loxP methods.
     For this, we improved existing protocols to extend the duration of in vitro plasmablast differentiation and showed that Rosa26(Cas9/+) B cells infected with Blimp1 or Xbp1 sgRNA-expressing retroviruses recapitulated the Blimp1 and Xbp1 mutant phenotypes in this proof-of-principle experiment. Moreover, Cre retrovirus-mediated deletion of Irf4, Ikaros and Aiolos strongly impaired plasmablast differentiation in this optimized system.
     To discover new regulators of plasma cell differentiation, CRISPR/Cas9-based screens will be performed with pooled sgRNA libraries targeting all known upregulated genes in plasmablasts and plasma cells, followed by individual validation of the best hits. Selected top-ranked genes will be analyzed in vivo by conditional mutagenesis with newly generated, plasma cell-specific Cre lines. Regulated target genes of IRF4, Ikaros, Aiolos, XBP1 and the XBP1-regulated transcription factor Bhlha15 will be identified in plasmablasts by ChIP- and RNA-seq analyses. Target genes with potentially interesting functions will be further characterized by CRISPR/Cas9- or Cre/loxP-mediated mutagenesis.
     These experiments will provide fundamentally new insight into the molecular mechanisms controlling the development and function of antibody-secreting cells, which are the essential effector cells of humoral immunity.
Ro-Boost inno smes – boosting the innovative potential of romanian smes

In the context of innovation-divided Europe and scarce consultancy in RDI, Macro Region 4 Romania is in full process of
moving towards a ""turning point"" of economic positioning in a climate of globalization, disruptive innovations and circular
economies. This dynamic brings to surface impediments innovation actors in the region face multiple challenges, while their
ability to overcome them is crucial to the impact of such changes. The core members of the Ro-Boost SMEs consortium are
aware that it is time for smart action in order to achieve the goal of reducing the innovation divide among companies. Based
on the vision stated in the Ro-Boost SMEs Implementation Strategy, the core members of the consortium jointly elaborated
the project ""Ro-Boost Inno SMEs"" aimed at consolidating innovative businesses - rooted into the Smart Specialisation
Strategy - and to expand their position within the sector global value chains. To achieve this goal, dedicated innovation
support envisaged at the beginning of 2015 shall be continued in order to increase added value of SMEs and innovative
sectors in the global economy, using an innovative delivery system and consolidating the community of innovators.
The proposal is built around the expertise of relevant partners at Macro Region 4 level and in-depth competences gained in
2015-2016. It shall also capitalize on the impact generated in the previous period in order to gain further recognition of the
innovation management as success driver among SMEs in terms of both economic impact and innovation culture within
business environment.
Fostering earth observation market uptake thanks to natural and holistic access to added value data generated through cutting-edge artificial intelligence technologies

SnapEarth will unlock new value, derive actionable service ideas on top of EO big data collections, and anticipate future
priorities by leveraging cutting-edge Artificial Intelligence and Cloud technologies and tools. Thanks to an innovative cloud
agnostic product, SafeScale that is already operational on Copernicus RUS project led by CSSI, users and service providers
on top of SnapEarth will benefit, in a transparent way, from processing platforms and data collections provided by any of the
future C-DIAS and any cloud provider. This cloud brokering solution is providing a performant, cost effective environment,
also protecting their investment, for the future third parties which are building their own services. The major breakthrough of
SnapEarth comes with a new data analytics service, EarthSignature, which aims to automatically extract semantic
information from satellite imagery. The extracted semantic information will be indexed by QWANT search engine and then
be easily accessible to a wide range of user communities. EO experts and third parties will be able to train deep learning
processing chains using their database of labelled EO images. The database will be near real time enriched. Therefore,
SnapEarth allows the market move from analysing EO Big Data towards realizing Fast Data. It makes possible to buy basic
imagery analysis as a commodity – much like we buy foundation data today. Several user communities are ready to engage
in this new approach. SnapEarth proposes already several pilots projects. The first one (EarthSearch) will boost QWANT
number of users through access to this wealth of data through natural language. The second one (EarthPress) involves
press users who are very interested having contextual data linked to news. The following ones are linked to several EO
vertical markets: EarthClimate, Agri, and Food. The last one EarthSelf-service is dedicated to professional third parties in the
same model of the DIAS but ensuring independence.
Development of radiation hard edgeless detectors with current terminating structure on p-type silicon

Abstract The development of edgeless Si detectors was stimulated by the tasks of the total pp cross-section study in the TOTEM experiment at the Large Hadron Collider at CERN. For this, the dead region at the detector diced side should be reduced below 50 μm. This requirement is successfully realized in edgeless Si detectors with current terminating structure (CTS), which are now operating at LHC. The development of the experiment and future LHC upgrade need the elaboration of radiation hard version of edgeless Si detectors. The current investigation represents an extension in understanding on edgeless detectors operation and development of a new issue – edgeless detectors with CTS on p-type Si.
The Miles Before Formal Methods - A Case Study on Modeling and Analyzing a Passenger Lift System

Cyber-Physical Systems (CPS) pervade our everyday lives. As users, we need assurances that such systems satisfy requirements on safety, reliability, security and interoperability. CPS presents a major challenge for formal analysis because of their complexity, physical dependencies and non-linearity, and for smart CPS - the ability to improve their behavior over time. Existing approaches on analyzing CPS (e.g., model checking and model-based testing) often assume the existence of a system model. Such approaches have limited application in practice as the models often do not exist. In this work, we report our experience on applying a three-step approach to analyzing a practical CPS: a passenger lift system in a commercial building. The three steps are (1) determining the right level of system abstraction, (2) building the model automatically using grammatical inference, and (3) analyzing the model. The inferred model is in the form of a probabilistic deterministic real time automaton, which allows us to verify the system against properties demanded by the lift requirement. The resulting models form the basis of formal analysis and potentially other approaches. We believe that our approach and experience are applicable to other CPSs.
Welcome Media System

The project includes a series of integrated initiatives relating to information and communication  involve the use of ICT to improve information services for tourists.  Starting from actions aimed at developing cross-border cooperation,  through high-tech tools, encourage the promotion of content and  typical shared, the project will focus on initiatives aimed at disseminating  production through most of those instruments for the promotion of potential tourist, but  even greater service for tourists already in the area. particularly  are enabled tools and technologies (eg. totems full screen) that  will provide information services to tourists, but also to promote  outside the territorial excellence.
APPARATUS FOR INSPECTION OF A FLAT STRUCTURE

The apparatus for inspection of a flat structure (8) has an upper carriage (10) which is intended for arrangement on the upper face of the flat structure (8) and a lower carriage (20) which is intended for arrangement on the lower face of the flat structure (8). Magnets which are arranged in the upper and lower carriages (10, 20) hold the upper and lower carriages (10, 20) on opposite sides of the flat structure (8). A drive device, which has a caterpillar drive with two drive belts (12) separated laterally moves the apparatus over the flat structure (8). Each drive belt (12) may have its own drive, and the drive belts (12) can be driven at different speeds. A measurement device (36, 50) can be provided on at least one of the carriages (10, 20), in which case the measurement device can be connected as a module (30) to the upper or lower carriage (10, 20). A movement distance determination device (40) can be provided for determination of the movement distance travelled by the apparatus. The measurement module (30) can be mounted in a floating manner in the upper carriage (10), with an opposing measurement plate being mounted in a floating manner in the lower carriage (20), with additional, dedicated magnets being provided on the measurement module (30) and on the opposing measurement plate, in order to hold them on the opposite sides of the flat structure.