SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
EXPANDABLE VERTICAL DIP PRETREATMENT AND ELECTRO-DEPOSITION SYSTEM

A vertical dip pretreatment and electro-deposition system has a plurality of dip stations and a plurality of spray stations. The process limited dip stations, such as the degrease dip station, the phosphate dip station and the electro-coat dip station, have expandable dip tanks which can have a bulkheads that divide the tanks into two sections providing the tanks with two compartments, or have removable end walls that can be removed and replaced with a tank section. If the bulkhead divided tanks are used, during the initial period of operation when production rates would typically be less than ten to twelve jobs an hour, one compartment of each expandable dip tank is used for immersion and the other compartment left dry or used for other purposes such as storage. When volume increases to above the design capacity, the expandable tanks are expanded. If bulkhead divided tanks are used, the bulkhead is removed which joins the first and second compartments, thus doubling the length of the tank. If the removable end wall tanks are used, the removable end walls are removed and replaced with tank sections to double the length of the tanks. In operation, the system is then set up so that after the product is lowered in the expanded tank, it stays in the first half of the expanded tank for half or less of the process time. The product is then kept in the lowered position in the expanded tank and moved to the second section of the expanded tank where it remains until the end of the required process time. The index time for the system is thus half or less of the total cycle time of the process. In this manner, production throughput of the system is increased.
Gas sensing through evanescent coupling of spoof surface acoustic waves

Abstract An ultrasonic gas sensor based on evanescent coupling of spoof surface acoustic waves between two surface phononic crystals containing trapezoidal grooves on rigid slabs is theoretically and experimentally demonstrated. Sensing properties for carbon dioxide in dry air at 25 °C and 760 Torr are investigated as an example. Band structure analyses reveal two spoof surface acoustic wave bands with opposite parities when the separation of surface phononic crystals is 1.5 times the periodicity of grooves. The beat length varies with frequency and carbon dioxide volume fraction, where the increase of the latter results in red shift of a sharp intense output peak at 59.69 kHz at a rate of 17.70 mHz/ppm and 16.20 mHz/ppm for carbon dioxide volume fractions up to 10,000 ppm, as measured through Finite-Element Method simulations and experiments, respectively. Gas sensing can also be achieved by measuring the output acoustic intensity at constant frequency, which exhibits a steep decrease with carbon dioxide volume fraction up to 2000 ppm.
Key factors in the acceptability of treatment as prevention (TasP) in Scotland: a qualitative study with communities affected by HIV

There is a clear need to understand the factors that might prevent and/or facilitate the effective use of HIV treatment as prevention (TasP) at an individual level. This paper reports on findings from the first qualitative study in the UK exploring the acceptability of TasP among gay, bisexual and/or men who have sex with men (MSM) and migrant African communities in Scotland.We conducted seven exploratory focus group discussions (FGDs) with convenience samples of MSM (five FGDs, n=22) and mixed-gender African (two FGDs, n=11) participants. Of these, three FGDs were conducted with HIV-positive MSM (n=14) and one FGD with HIV-positive Africans (n=8). We then conducted 34 in-depth interviews (IDIs) with a purposive sample of MSM (n=20) and Africans (n=14, women=10). Half were HIV-positive (MSM, n=10; African, n=7). FGD and IDI data were analysed thematically drawing on predetermined and emergent themes.We found that inequalities in HIV literacy could be a barrier to TasP, as could social constraints, such as criminalisation of transmission, increased risk of sexually transmitted infection and increased burden of treatment. We also identified psychological barriers such as perceptions of risk. However, relationships and shared decision making were identified as potential facilitators for TasP.Our results suggest that potential use and management of TasP may not be straightforward. It could be contingent on reducing inequalities in HIV literacy, minimising the perceived burden of treatment and other potential risks, and addressing the dynamics of existing and socially acceptable risk management strategies, especially in relation to long-term serodiscordant relationships.
CETP inhibitors downregulate hepatic LDL receptor and PCSK9 expression in vitro and in vivo through a SREBP2 dependent mechanism

CETP inhibitors block the transfer of cholesteryl ester from HDL-C to VLDL-C and LDL-C, thereby raising HDL-C and lowering LDL-C. In this study, we explored the effect of CETP inhibitors on hepatic LDL receptor (LDLR) and PCSK9 expression and further elucidated the underlying regulatory mechanism.We first examined the effect of anacetrapib (ANA) and dalcetrapib (DAL) on LDLR and PCSK9 expression in hepatic cells in vitro. ANA exhibited a dose-dependent inhibition on both LDLR and PCSK9 expression in CETP-positive HepG2 cells and human primary hepatocytes as well as CETP-negative mouse primary hepatocytes (MPH). Moreover, the induction of LDLR protein expression by rosuvastatin in MPH was blunted by cotreatment with ANA. In both HepG2 and MPH ANA treatment reduced the amount of mature form of SREBP2 (SREBP2-M). In vivo, oral administration of ANA to dyslipidemic C57BL/6J mice at a daily dose of 50 mg/kg for 1 week elevated serum total cholesterol by approximately 24.5% (p < 0.05%) and VLDL-C by 70% (p < 0.05%) with concomitant reductions of serum PCSK9 and liver LDLR/SREBP2-M protein. Finally, we examined the in vitro effect of two other strong CETP inhibitors evacetrapib and torcetrapib on LDLR/PCSK9 expression and observed a similar inhibitory effect as ANA in a concentration range of 1-10 μM.Our study revealed an unexpected off-target effect of CETP inhibitors that reduce the mature form of SREBP2, leading to attenuated transcription of hepatic LDLR and PCSK9. This negative regulation of SREBP pathway by ANA manifested in mice where CETP activity was absent and affected serum cholesterol metabolism.
Ultra-Low power technologies and memory architectures for iot

The goal of the PRIME project is to establish an open Ultra Low Power (ULP) Technology Platform containing all necessary design and architecture blocks and components which could enable the European industry to increase and strengthen their competitive and leading eco-system and benefit from market opportunities created by the Internet of Things (IoT) revolution. 
Over 3 years the project will develop and demonstrate the key building blocks of IoT ULP systems driven by the applications in the medical, agricultural, domestics and security domains. This will include development of high performance, energy efficient and cost effective technology platform, flexible design ecosystem (including IP and design flow), changes in architectural and power management to reduced energy consumption, security blocks based on PUF and finally the System of Chip and System in Package memory banks and processing implementations for IoT sensor node systems.
Developped advanced as 22nm FDSOI low power technologies with logic, analog, RF and embedded new memory components (STT RAM and RRAM) together with innovative design and system architecture solutions will be used to build macros and demonstrate functionality and power reduction advantage of the new IoT device components.
The PRIME project will realize several demonstrators of IoT system building blocks to show the proposed low power wireless solutions, functionality and performance of delivered design and technology blocks. 
The consortium semiconductor ecosystem (IDMs, design houses, R&D, tools & wafer suppliers, foundries, system/product providers) covers complementarily all desired areas of expertise to achieve the project goals.  
The project will enable an increase in Europe’s innovation capability in the area of ULP Technology, design and applications, creation of a competitive European eco-system and help to identify market leadership opportunities in security, mobility, healthcare and smart cost competitive manufacturing.
Periodicity determination of lacustrine cycles from the Devonian of Northern Scotland

Synopsis The Middle Old Red Sandstone (mid Devonian) of the Orcadian Basin in northern Scotland is composed predominantly of cyclic lacustrine deposits. The cyclicity recorded reflects regular fluctuations in lake levels that have been attributed to climatic variability resulting from regular variations in the Earth9s orbital parameters (Milankovitch cycles). However, previous estimates and calculations of the periodicities of these events have produced highly variable results, and no consistent approach has emerged. Variability in the estimated thicknesses of the sequences and regular revisions of the Devonian timescale, combined with poorly defined absolute dating of stratigraphic boundaries, have hindered accurate calculations of cycle periodicities. This study reviews the factors involved in the calculation of published periodicities for the lacustrine cycles of the Orcadian Basin and considers the effect of recent revisions to the Devonian timescale and stratigraphic thicknesses. When considered alongside detailed examination of well exposed sections from Easter Ross, Caithness and Orkney, the calculation of cycle periodicities provides consistent results reflecting the dominance of Precessional (19 886 years) and modulating Eccentricity (100 000 years) cycles calculated for the Devonian.
THE FUNCTION OF PHOSPHORUS , NICKEL AND H2S IN THE HDN OF PIPERIDINE AND PYRIDINE OVER NiMoP/Al2O3 CATALYSTS

The effect of phosphorus in the hydrodenitrogenation (HDN) of piperidine and pyridine over NiMo/Al2O3 catalysts was studied. In the absence of H2S no effect of P was found, but in the presence of H2S the HDN activity of NiMo/Al2O3 catalysts decreased as the P content in the catalysts increased. It is concluded that phosphorus has a negative effect on the C-N bond cleavage in piperidine, as well as on the subsequent hydrogenation of the C5 alkene intermediates. Also the influence of Ni was found to depend on the reaction conditions. A substantial promotion effect of Ni could only be observed in the presence of H2S, both in the C-N bond cleavage of piperidine and in the pyridine hydrogenation. The activity for the HDN of piperidine of NiMo(P)/Al2O3 catalysts increased with increasing H2S concentration up to H2S/H2 = 12.5 × 10−3 mol/mol.
The game changer drug to cure alcohol use disorders

Alcohol use disorders (AUD) is a disease characterised by uncontrolled alcohol consumption. 283 million persons worldwide suffer from alcohol mise use which cause more than 3 million dead and 132.6 million disability-adjusted life years. Alcoholism has also huge damaging effects on families, communities and the overall society. Current drug therapies against AUD are unsuccessful due to poor efficacy and strong side effects. That situation leads to low patient recovery and only 10% of AUD people seeking for treatment.  
In this context, Kinnov-Therapeutics has developed a new revolutionary first-in-class drug allowing patients to control their alcohol consumption. KT-110 drug will highly impact the European burden of AUD by decreasing alcohol consumption on AUD patients by 70% leading to triple the number of AUD people seeking for treatments and save more than 5 million lives per year and several billion of social cost expenses. The efficacy of KT-110 is related to its action on a newly discovered pathway highly implicated in alcohol addiction. This major understanding of AUD addiction mechanism was granted the European college of neuropsychopharmacology Neuropsychopharmacology Award in 2009. 
After 20 years of intensive research and pre-clinical development, KT-110 has been accepted by the french regulatory agency for its first-in man phase II clinical trial by the end of 2018. This will be the main achievement of SMEi2 project. Moreover, all necessary actions for successful commercialisation to pharma companies (licensing deals) as well as continuous and updated IP and FTO issues are planned to be implemented during the SMEi2. 
Through StopAddict project KT-110 will become the next leader of AUD treatments by generating €117m of cumulative revenues between 2025-2027. Our project will also allow to create more than 400 direct and indirect European jobs.
Exploring Hypersexual Behavior in Men with Parkinson's Disease: Is it Compulsive Sexual Behavior?

A range of impulse control disorders has been described in Parkinson's disease, including compulsive sexual behavior. Excessive sexual demands of parkinsonian men can lead to considerable tension within the couple. Thorough sexual interviews reveal that these cases may reflect various types of sexual dysfunctions that present as hypersexuality.This study aims to analyze cases of presumed and true compulsive male sexual behavior, and to propose a practical tool for clinicians, assisting them with the diagnosis and management of compulsive sexual behavior and other sexual dysfunctions in parkinsonian patients.We describe four male patients with Parkinson's disease from the movement disorders clinic, which were referred to the sex therapist as suspected hypersexuality.The sexual assessment revealed that only one of the cases involved true hypersexuality due to compulsive sexual behavior. The other three presented with erectile dysfunction, difficulties reaching orgasm (delayed ejaculation), and a gap in desire within the couple.Complaints about hypersexual behavior in patients with Parkinson's disease must be carefully evaluated, involving a multidisciplinary team. A comprehensive diagnostic and therapeutic algorithm is suggested.
Many Hands Make Light Work - On Ensemble Learning Techniques for Data Fusion in Remote Sensing

In this paper we discuss the use of ensemble methods in remote sensing. After a review of the relevant state of the art in ensemble learning - inside and outside the remote sensing community - we provide the necessary theoretical background of this research field. This includes a discussion of the bias/variance tradeoff that is a key notion in machine learning and especially ensemble learning. We provide a review of three of the most relevant and prominent techniques in ensemble learning, namely the Random Forest, Extra Trees and the Gradient Boosted Regression Trees algorithms. All algorithms are assessed in terms of their theoretical properties as well as applicability for remote sensing use cases. Finally, in the experimental section we compare their performance in challenging remote sensing datasets with different properties, while discussing again the reasons that the mechanics of each algorithm might give it an advantage under certain conditions.
An integrated study of geochemistry and mineralogy of the Upper Tukau Formation, Borneo Island (East Malaysia): Sediment provenance, depositional setting and tectonic implications

Abstract An integrated study using bulk chemical composition, mineralogy and mineral chemistry of sedimentary rocks from the Tukau Formation of Borneo Island (Sarawak, Malaysia) is presented in order to understand the depositional and tectonic settings during the Neogene. Sedimentary rocks are chemically classified as shale, wacke, arkose, litharenite and quartz arenite and consist of quartz, illite, feldspar, rutile and anatase, zircon, tourmaline, chromite and monazite. All of them are highly matured and were derived from a moderate to intensively weathered source. Bulk and mineral chemistries suggest that these rocks were recycled from sedimentary to metasedimentary source regions with some input from granitoids and mafic-ultramafic rocks. The chondrite normalized REE signature indicates the presence of felsic rocks in the source region. Zircon geochronology shows that the samples were of Cretaceous and Triassic age. Comparable ages of zircon from the Tukau Formation sedimentary rocks, granitoids of the Schwaner Mountains (southern Borneo) and Tin Belt of the Malaysia Peninsular suggest that the principal provenance for the Rajang Group were further uplifted and eroded during the Neogene. Additionally, presence of chromian spinels and their chemistry indicate a minor influence of mafic and ultramafic rocks present in the Rajang Group. From a tectonic standpoint, the Tukau Formation sedimentary rocks were deposited in a passive margin with passive collisional and rift settings. Our key geochemical observation on tectonic setting is comparable to the regional geological setting of northwestern Borneo as described in the literature.
Second generation beacon for galileo/egnos egnss  search and rescue applications

The HELIOS project aims at providing a Second Generation range of Beacons (SGB) and associated antennas designed to operate with the full capability of the new Meosar Cospas/Sarsat (C/S) International Programme (a satellite-based Search And Rescue (SAR) distress alert detection and information distribution system), embedded in the Navigation Satellite Systems as GALILEO. 
The Search & Rescue community is at a turn of its history. New satellite systems develops the MEOSAR constellation of Cospas-Sarsat system, EGNOS improves significantly the performance of localization introducing new capabilities and new operations impossible before, GALILEO unique differentiation with the RLS added to the performance of the system will contribute to save more lives at sea and on land.
The key objectives of the HELIOS project are:
1 - Defining, developing Products (beacons and associated antennas) compatible with EGNSS & SAR services and latest end-users’ requirements.
2 - GALILEO EGNSS & SAR System validation.
3 - Certifications for commercialization.
The HELIOS consortium composed of Orolia, Cobham aerospace communications, CNES, SIOEN, Air France, and Airbus, is involved in different relevant international working groups (Cospas-Sarsat, ICAO, EUROCAE), and will ensure that the development phase of the SGB will be in line with the compatibility and interoperability required by the Cospas-Sarsat.
Gathering the knowledge of major players recognized in their industry worldwide, the HELIOS partners project will give the vehicle to the European Industry to lead the way for safer, more innovative systems responding to current and evolving market problems.
Ageing effects on human aorta: from shape to flows

Age-related remodeling of the aorta is associated with alterations in morphology and hemodynamics . These alterations are involved and accelerated in the presence of cardiovascular diseases (CVDs), suggesting that they are the likely culprits that underlie the increased cardiovascular risk associated with ageing . However, an advanced characterization of the age-related morphological/hemodynamic alterations and on their synergistic interplay is missing, mainly because encumbered by time-consuming operator-dependent tasks. In this 36 months global fellowship (University of Toronto, Canada and Politecnico di Torino, Italy), the potential clinical utility of such a characterization will be addressed, developing tools for the quantitative assessment of the age-associated alterations in a large-scale cross-sectional dataset of aortas from subjects with successful ageing. After training on phase-contrast magnetic resonance imaging (PCMRI) technique, for each subject the 4D velocity field will be acquired. Quantitative morphometric parameters will be defined and evaluated in vivo. To investigate aortic hemodynamics, PCMRI will be complemented by computational fluid dynamics (CFD) to overcome PCMRI limitations on temporal/spatial resolution and wall shear stress quantification . The impact of CFD assumptions will be assessed by validating CFD results with PCMRI measurements. To improve CFD results accuracy, in the return phase PCMRI data will be incorporated into the numeric simulations, through the assimilation of the acquired flow fields into the CFD solver. Descriptors quantifiable in vivo and able to simplify the understanding of the complex 4D hemodynamic and of age-associated remodeling will be defined. The new tools for diagnostic/prognostic purposes will be integrated within the open-source Vascular Modelling ToolKit, to facilitate and streamline the diagnosis and monitoring of a wider range of CVDs when applied to other vascular districts (e.g. carotid, aneurysm).
A Survey on Procedural Modelling for Virtual Worlds

Procedural modelling deals with semi-automatic content generation by means of a program or procedure. Among other advantages, its data compression and the potential to generate a large variety of detailed content with reduced human intervention, have made procedural modelling attractive for creating virtual environments increasingly used in movies, games and simulations. We survey procedural methods that are useful to generate features of virtual worlds, including terrains, vegetation, rivers, roads, buildings and entire cities. In this survey, we focus particularly on the degree of intuitive control and of interactivity offered by each procedural method, because these properties are instrumental for their typical users: designers and artists. We identify the most promising research results that have been recently achieved, but we also realize that there is far from widespread acceptance of procedural methods among non-technical, creative professionals. We conclude by discussing some of the most important challenges of procedural modelling.
Construction of the building and extension of the warehouse for medical production

Revitalisation of the building of the “brownfield” type (original locksmith workshops Dolu Dukla) followed by the introduction of new production of right-wing material (incision foils, surgical operating sets, etc.). It is a long-term unused building, which is located within the industrial zone of Dukla Dolu, which will be reconstructed (partial demolition of the existing building and extension of warehouses) incl. construction of paved areas. During 2021-2022, CZK 16.3 million excluding VAT will be invested.
On the trade-off between remanufacturing and recycling

Motivated by interactions with two reverse-logistics firms, we analyse the trade-off between two product-recovery approaches: recycling and remanufacturing. We consider a manufacturer who produces and markets a product with the objective of maximising profit. A unit of the product consists of two modules: A and B. After recovery, Module A can be recycled to recover its raw material, which can then be used to produce new units of either module. A recovered Module B is remanufactured and can be used in a remanufactured unit. Under this setting, we investigate three options: 1	
only recycling of Module A
	
2	
only remanufacturing of Module B
	
3	
recycling of Module A and remanufacturing of Module B.
	


We provide a complete theoretical characterisation of the regions of optimality of each option. Useful insights are offered by examining the influence of the fraction of green consumers, the take-back fraction, and product design characteristics.