SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Aquaculture meets biomedicine: innovation in skeletal health research.

Skeletal anomalies in farmed fish are a continuous problem for global aquaculture, affecting fish welfare, performance, and product quality. Aquaculture research has made considerable progress in reducing the incidence of deformities, but new species, intensified production, the damned for sterile fish, delicate early life stages and new fish feed ingredients are a continuous challenge. The use of zebrafish (Danio rerio) and medaka (Oryzias latipes) as models for research into human skeletal diseases such as osteoporosis, osteopetrosis and degenerative joint diseases is increasing, however their potential as models for farmed fish has not been sufficiently explored. These models offer the possibility to obtain deeper insights into the fundamental mechanisms that can cause skeletal malformations in humans and in farmed fish. A framework for communication and scientific exchange between the aquaculture and biomedical sectors would benefit all stakeholders and advance scientific understanding of the problem. We propose a joint inter-sectorial training network to increase the mobility and visibility of scientists between aquaculture research and the biomedical sector using small fish models. The proposed ESR programs will provide career development to young researchers in the field of skeletal biology through international and multidisciplinary training on innovative molecular, histological, biochemical and cell culture methodologies relevant to both sectors. The network combines stakeholders from 7 European Universities, a US research hospital, and one Biological Institute. Commercial interests are represented by two Economy departments, one aquaculture and a major fish feed production company. This structure allows the flow of information and people between the biomedical and aquaculture sectors, and between academic and applied sectors, thus addressing several objectives of the Europe 2020 strategy and ensuring a direct route from knowledge to application.
General aviation improved navigation and surveillance

The objective is to validate concepts on avionics and use of instrument flight procedures tailored to General Aviation that enable integration and inclusion of GA within high density airspace or environments in which GA is constrained due to proximity of adjacent airports or airways for scheduled airlines or the military. The project builds on the concept demonstrated to the EVA project considering the suitability of ground monitoring from aerodromes with basic ATS or ground services and testing the viability for the use of PBN procedures more tailoured to the capabilities of GA and the limitations of operations in dense airspace.
Convergence of positive and negative reinforcement in fentanyl addiction

F-Addict strives to unravel the neural circuits driving compulsion in fentanyl addiction. We ask the question how fentanyl causes fast transition from medical or recreational controlled drug use to compulsive consumption. About a third of opioid users eventually loose control, which increases the risk of death by overdose; a number that is even higher for fentanyl and definitely exceeds the transition observed with psychostimulants. The neural correlate of this difference remains elusive. We posit that repetitive withdrawal leads to strong negative reinforcement, which in conjunction with inherent positive reinforcement favors the transition to compulsion. F-Addict will uncover the synaptic processes and neuronal population activity leading to addiction in a mouse model of oral fentanyl self-administration. Much preliminary data implicate activity in the mesolimbic dopamine system and upstream subcortical regions (paraventricular thalamus/habenula/basolateral amygdala) in positive and negative reinforcement, respectively. In addition, top down control, in particular by the orbitofrontal cortex may drive compulsive drug use. The proposed project will harness advanced circuit investigations for an innovative, original perspective: how does positive and negative reinforcement in fentanyl addiction contrast with current circuit models of addiction that are based on psychostimulants? In a translational spirit, F-Addict will also examine the effects of oral substitution with methadone and buprenorphine, recognized therapies for opioid addiction. Much preliminary data provides proof of feasibility and principle. We are confident that our approach at the frontiers of modern neurosciences carries the potential for groundbreaking results to answer a timely question. Unraveling the neural basis of fentanyl addiction will enhance the molecular understanding of circuit modulation to shape future therapies facing the still growing opioid epidemic.
Democratic Citizenship and Denationalization

Are democratic states permitted to denationalize citizens, in particular those whom they believe pose dangers to the physical safety of others? In this article, I argue that they are not. The power to denationalize citizens—that is, to revoke citizenship—is one that many states have historically claimed for themselves, but which has largely been in disuse in the last several decades. Recent terrorist events have, however, prompted scholars and political actors to reconsider the role that denationalization can and perhaps should play in democratic states, in particular with respect to its role in protecting national security and in supporting the global fight against terror more generally. In this article, my objective is to show that denationalization laws have no place in democratic states. To understand why, I propose examining the foundations of the right of citizenship, which lie, I shall argue, in the very strong interests that individuals have in security of residence. I use this formulation of the right to respond to two broad clusters of arguments: (1) those that claim that it is justifiable to denationalize citizens who threaten to undermine the safety of citizens in a democratic state or the ability of a democratic state to function as a democratic state, and (2) those that claim that it is justifiable to denationalize dual citizens because they possess citizenship status in a second country that is also able to protect their rights.
COMBINATION THERAPY OF TETRACYCLIC QUINOLONE ANALOGS FOR TREATING CANCER

The present invention provides methods, compositions, and combinations for treating cancer via combined use of a compound of formula I or a pharmaceutically acceptable salt, ester, solvate and/or prodrug thereof, wherein A, Q, n, m, R7, R8, V, X1, X2, X3, X4, X5, X6, and X7 are as defined herein, and at least one therapeutically active agents selected from immunotherapeutics, anticancer agents, and anti-angiogenics.
A Comparison of the Gravimetric Geoid and the Geometric Geoid Using GPS/Leveling Data

The geoid is the level surface that closely approximates mean sea level and usually used for the origin of vertical datum. For the computation of geoid, various sources of gravity measurements are used in South Korea and, as a consequence, the geoid models may show different results. however, a limited analysis has been performed due to a lack of controlled data, namely the GPS/Leveling data. Therefore, in this study, the gravimetric geoids are compared with the geodetic geoid which is obtained through the GPS/Leveling procedures. The gravimetric geoids are categorized into geoid from airborne gravimetry, geoid from the terrestrial gravimetry, NGII geoid(geoids published by National Geographic Information Institute) and NORI geoid(geoi published by National Oceanographic Research Institute), respectively. For the analysis, the geometric geoid is obtained at each unified national control point and the difference between geodetic and gravimetric geoid is computed. Also, the geoid height data is gridded on a regular grid so that the FFT method can be applied to analyze the geoid height differences in frequency domain. The results show that no significant differences in standard deviation are observed when the geoids from the airborne and terrestrial gravimetry are compared with the geomertric geoid while relatively large difference are shown when NGII geoid and NORI geoid are compared with geometric geoid. Also, NGII geoid and NORI geoid are analyzed in frequency domain and the deviations occurs in long-wavelength domain.
Serologic study of Bartonella sp. infection among human population of Southern Spain

The purpose of this study was to determine the prevalence of IgG antibodies against Bartonella sp. in a randomly selected sample from the population of the patients of North Sanitary District of Jaén.We used a commercially available immunofluorescent test (Focus-Technology IFA Bartonella quintana and B. henselae test).Six hundred five healthy individuals were divided by sex into three age groups. We detected that 13.55% and 11.07% subjects were IgG seropositive to B. henselae and B. quintana, respectively.Our data show that the prevalence of both Bartonella species in Andalusia (Southern Spain) is relatively high. No statistical difference in the seropositivity was observed among these groups. In both cases, the IgG antibody titers ranged from 1/128 to 1/512.
Effect of culture medium on the production and virulence of submerged spores of<i>Metarhizium anisopliae</i>and<i>Beauveria bassiana</i>against larvae and adults of<i>Aedes aegypti</i>(Diptera: Culicidae)

Three Metarhizium anisopliae and three Beauveria bassiana isolates were cultivated in media containing casamino acids, soybean flour or sunflower seed flour and were shaken for three days. M. anisopliae presented similar yields of around 106 submerged spores/ml without significant differences among them, whereas B. bassiana produced yields of around 108 spores/ml, of which GHA strain produced more submerged spores in the casamino acids medium. The other two strains showed no significant difference in the production of submerged spores in the three media used. Differences in mortality on Aedes aegypti larvae were observed with the submerged spores of Metarhizium depending on isolate and medium used. M. anisopliae 2157 caused significantly higher mortality (40%) when cultivated in casamino acids medium. It presented an LC50 of 8.93 × 105 submerged spores/ml water against mosquito larvae five days after application, whereas it caused 27% mortality in Ae. aegypti adults 10 days after application. In conclusio...
Working capital subsidy for Taurus Protection Group Sp. z o.o.

The project concerns support to the entrepreneur in providing liquidity and support to day-to-day activities due to the financial difficulties that have occurred to the entrepreneur as a result of the COVID-19 outbreak. Financial assistance under scheme SA.57015 (2020/N)
Foreign Direct Investment and Economic Growth in Zambia

This paper aims to examine the causality relationship between foreign direct investment inflow (FDI) and economic growth (GDPGR) in Zambia using the time-series analyses. All analyses are conducted with the annual data of foreign direct investment and real gross domestic product of Zambia over the years of 1970 and 2011. The results of the ADF unit root test show that the time-series data are non-stationary at levels, but become stationary in the first differences. Besides, the results of the Johansen co-integration test indicate that both series are co-integrated, and long-run equilibrium thus exists between FDI and GDPGR. Findings of Granger-causality test suggest that there is a one-way causality effect running from FDI to GDPGR.
SMART ADRIA Blue Growth

SMART ADRIA BLUE GROWTH (SABG) is the long-term strategy to leapfrog the economy of the Programme Area (PA) by fostering the framework conditions for the Blue Growth of cross-border SME’s, while creating hybrid governance structures supportive of 4th industrial revolution. SA approach is an innovative marriage engagement of Blue Growth, Smart Specialization and Quadruple Helix of innovation - linking UNIversity, INDustry, CIVil society and GOVernment - to Accelerate the Transfer of Research and Innovation Results to Regional Blue Growth. The PA lags behind the European economy in terms of economic development   and innovation, with main needs being the weak competitiveness of SME’s and their insufficient cooperation with clusters and research centres. Italy, Albania and Montenegro recognized SA as a key component of the economy of the countries, to be further developed also in the framework of international regional cooperation. SMART ADRIA aims to identify the most promising local business sectors, define instruments and tools to promote Blue Growth and entrepreneurial culture into those economic sectors and create a joint strategy for GOVernment to manage efficiently the transition towards 4th industrial revolution.
Main Outputs:
O.T

1.4   Three (3) virtual Blue Labs established IT, MNE, ALB supporting commercial exploitation, testing and piloting innovative products and services
O.T

3.1   Capacity building in Blue Growth
O.T

3.2   ON LINE Capacity Building platform in Blue Growth
O.T

2.1   1 cross-border Blue Growth Cluster
O.T

2.2   SMEs received Blue Growth related services
The right to work for men and women with disabilities - successful collaboration between employers and support systems using the workplace as an arena for work inclusion

The employment rate of persons with disabilities across Europe is much lower than of the general population and the
disability employment gap has remained considerable, independently of labour market policies. Over time different
approaches to work inclusion of persons with disabilities have been developed, where support-side approaches, especially
supported employment methods, that are using the workplaces as instruments of inclusion, have been shown effective. The
collaboration between employer and the support system is crucial when using the workplace as an arena for work inclusion,
but there is a lack of research on employer-support system relations and how they can be formed to facilitate increased employment of  persons with disabilities.
Using theoretical frameworks from the field of sociology and psychology, and by drawing conclusions from qualitative data, this project addresses successful collaboration between employers and support systems in work inclusion of men and women with disabilities. Results from observation/interview studies in Norway and Sweden and insights from a literature review will inform support-side approaches and facilitate work inclusion. During the fellowship will benefit from the expertise of the INTEGRATE core research group, at OsloMet - Oslo Metropolitan University and its international expert network and from short visits to other European excellence research centers in work inclusion. Building on my previous work and skills in labour market and disability research, the project activities will lead to further development of my professional maturity as a researcher, while the results will have a key impact on the development of effective support-side methods and as called for in EU policies, on the labour market participation of persons with disabilities.
Sustable (sustainable table) – Sustainable table

The project will develop a high-quality and sustainable universal table that meets the necessary conditions for organising various events.
New solutions for the environmental impact remediation of brine discharges

In order to meet the rising water demand required by an expanding population, which has already crossed the 7 billion mark
and is expected to reach 8,5 billion by 2030, and 9,7 billion in 2050 , desalination of seawater is envisaged as a solution to
provide a portion of the shortfall to fill the gap between supply and demand. Desalination becomes in many parts of the
world, and also in Europe, a promising option to combat water stress. Nonetheless, desalination plants generate huge
volumes of concentrates, also known as brines, which represent a potential hazard for marine ecosystems. Brines form a
very dense hypersaline plume (heavier than normal seawater) that spreads over large areas affecting marine ecosystems,
especially to seagrass meadows which are one of the most ecologically important ecosystems in coastal areas. ECOS has
developed VENTURI+ a diffuser solution, with a capacity of minimizing in a 99% the environmental impact associated to
brines discharges due to a potential dilution capacity 131% higher than conventional diffusers. Thus, VENTURI+ represents
a technological leap towards tackling one of the most robust environmental barriers that are holding the full deployment of
desalination plants.

ECOS requests funding to elaborate a feasibility study to define market uptake at National, European and International level.
The most important markets identified are the Mediterranean region (EU and non-EU countries), the Middle East, the US
and other countries such as India and China.
Fotokemijske i termičke transformacije diklor-supstituiranog butadienskog derivata

In order to study the influence of chlorine as a substituent on the thermal and photochemical behavior of conjugated butadiene systems, new dichloro derivative of butadiene 1 was synthesized by Wittig reaction. The new synthesized derivative 1 was exposed to thermal and photochemical reactions to prepare new unexplored thermal products. Getting the new complex polycyclic structures which depends on the electronic and steric effects of two chlorine atoms as substituent bounded on p-locations in the molecule was expected. Thermal reaction of the starting compound 1 leads to new product 2 in moderate-to-good yields. The starting compound 1 by photochemical reaction undergo intramolecular [2+2] cycloaddition giving benzobicyclic structures. These structures, because of its stability, cannot undergo further oxygenation reactions. The starting compound 1 as well as their product 2 were characterized by modern spectroscopic methods (one-dimensional 1H NMR, 13C NMR, IR and HRMS).
Risk and protective factors for psychopathology in adolescence

Mental health research suggests incarcerated adolescents display similar rates of
behavioural and emotional disorders as youth in psychiatric care. Several factors appear
to be related to psychological problems during adolescence, including: intellectual
disability; unhealthy family environments; childhood abuse (sexual, physical and
emotional abuse, and neglect); substance abuse; and poverty. In addition factors such as
parental mental illness, lack of perceived support, divorce, and single-parent families
have been linked to mental illness in adolescence. However, recent research indicates
that a number of factors, such as personality traits, social support, and emotional
intelligence, may act as mediators or protective factors against developing mental
illness in adolescence. The current study examined the rate of different forms of
psychological disturbance in a group of adolescents involved in the youth justice system
compared to a general high school sample (N = 145). Further, the study attempted to
identify the combination of emotional, intellectual, and psychosocial risk and protective
factors that best predict mental health status within these groups of adolescents. The rate
of psychological disturbances between the groups was examined using MANOVA and
MANCOVA, with the risk and protective factors for mental illness being examined with
logistic regression techniques. The MANCOVA results identified significant differences
between the youth justice and high school groups across five mental illness subscales:
Attention Deficit Hyperactivity Disorder, Conduct Disorder, Separation Anxiety,
Substance Abuse, and Adjustment Disorder. The youth justice group was found to
display significantly higher scores on these five subscales. Binary logistic regression
analyses identified a pattern of intellectual, emotional and psychosocial factors that
contribute to the prediction of clinically significant mental health problems for both groups of adolescents. Some of the key factors identified include neuroticism, criminal
conviction history, psychoticism, stress management skills, higher general mood, and
intrapersonal skills. While the results for the differences between the groups on the
psychopathology subscales are consistent with previous research, the number of
predictive factors that contributed to risk for mental illness were fewer than previously
identified. The results of the present study will enable the development of screening
tools to identify those adolescents in youth detention that are at highest risk of emerging
psychological disorders. Use of a screening tool has the potential to significantly
improve mental health outcomes due to such an instrument being able to indicate a need
for early intervention.
Integrated study of the role of b-cell receptor signaling in the development of follicular lymphoma

Signaling through the B cell receptor (BCR) is central to the development and maintenance of B cells. In light of the
numerous proliferative and survival pathways activated downstream of the BCR, it comes as no surprise that malignant B
cells would co-opt this receptor to promote their own growth and survival. However, direct evidence for BCR signaling in
human lymphoma has only come to light recently. In this proposal, I aim to better understand the role for antigen-dependent vs. antigen-dependent BCR signaling as a pathogenic mechanism in the progression of Follicular lymphoma (FL), a indolent lymphoid malignancy that retain BCR expression during malignant progression. Further investigating the intrinsic role of BCR might lead to the development of new therapeutic approaches based on the inhibition of the BCR pathways. Using an innovative loss-of -function RNA interference genetic screen together with an engineered in vitro system allowing to test FL patients's BCR reactivity and identify putative ligands, we will 1) determine whether BCR signalling in FL relies to
""chronic active"" or ""tonic"" signals and 2) identify the nature of antigen(s) recognized by FL's BCR that may sustain
signalling; each signalling pathway offering different opportunities for therapeutic intervention. 
For this project, I decided to chose the Louis Staudt’s group at the National Cancer Institute (NIH) for the outgoing phase since his group has been looking for years how to target B-cell receptor signaling as a treatment strategy. The unique expertise in the state-of the art functional genomic methodologies acquired during my stay at the NCI will be crucial for setting-up new scientific projects, promote extended collaborations and strongly support my re-establishement in Europe to reach an independent position.
Contextual conditions influencing the scheduler's work at a sawmill

This case study addresses the issue of how contextual conditions influence scheduling work in practice at a sawmill in Sweden. Based on observations and interviews, activity analysis was used to study the work activities of the main scheduler. It is shown how the contextual conditions related to constraints, either in the technical system and the technical scheduling tools used by the scheduler or in the social system, delimit the possible ways for the scheduler to perform his work. It is furthermore illustrated how the scheduler sometimes used the contextual conditions as a means to control the sawmill production. Moreover, the presence of the numerous uncertainties in the production process is shown. Finally, the study demonstrates that the scheduler's thorough knowledge, experience, and skills of both the technical and the social systems had immense influence in his ability to perform during daily scheduling work.