SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Comparative Study of Green Fruit Extract of Melia azedarach Linn. With its Ripe Fruit Extract for Antileishmanial, Larvicidal, Antioxidant and Cytotoxic Activity

The present study was carried out to compare the potential of green and ripen fruits aqueous extract against antileishmanial, larvicidal, antioxidant and brine shrimp cytotoxicity assay. A general antileishmanial, larvicidal, antioxidant and cytotoxic assays were performed at different concentrations. The green fruits expressed significant activity against L. tropica (LC 50 =0.41µg/mL), while the ripe fruits showed less activity (LC 50 =8227.51µg/mL). Upon larvicidal activity against Culex quinquefasciatus larvae, the green fruits extract expressed excellent results with LC 50 value 67.65µg/mL while ripe fruits showed less activity with LC 50 value 7171.18µg/mL. Similarly, for cytotoxicity assay for green and ripe fruits the LC 50 value obtained were 18.07µg/mL and 530.2µg/mL, respectively. The result for antioxidant potential showed that only the green fruits has some antioxidant potential (IC 50 232.23µg/mL) compared to ripe fruits (>1000µg/mL) against the reference drug (ascorbic acid). The total phenolics contents of the green fruits expressed good concentration 10.54 mg/g DW while ripe fruits have 5.32 mg/g DW.  From these results it can be concluded that green fruits has more active compounds than ripe fruits. The green plant material can be used as good source of antiprotozoal, insecticidal and anti-cancerous candidate.
Preparation of O-Carboxymethyl Chitosan by Schiff Base and Antibacterial Activity

A novel method of preparation O-Carboxymethyl chitosan (OCMC) was studied that the product was prepared by reaction of Schiff's base of chitosan. Schiff base of chitosan (BCTS) was synthesized by the reaction of chitosan with aromatic aldehyde, then BCTS reacted with chloroacetic acid and removed the group of amino protection to get the target product. The chitosan derivative was characterized by FT-IR spectroscopy, 1HNMR and elemental analysis. Elemental analysis results confirmed that the degree of substitution(DS) of OCMC was 0.83. Solubility of OCMC in water and organic solvents was demonstrated to be better than that of chitosan. The antimicrobial activities of chitosan and OCMC were investigated against Aspergillus niger and Staphylococcus aureus. The results indicate that the antimicrobial activity of OCMC was superior to chitosan.
Bond strength of composite materials after internal teeth bleaching using 30% carbamide peroxide

Introduction. Bond between composite materials and bleached teeth depends on the change of micro-morphological structure of enamel and dentin after the application of bleaching agent. Bleaching procedure can weaken adhesion of composite materials to hard tissues, where even just a presence of hydrogen peroxide may affect their polymerization. The aim of this study was to determine bond strength of composite materials after internal teeth bleaching using 30% carbamide peroxide. Material and Methods. The study was conducted on 20 extracted, endodontically treated human teeth. After internal teeth bleaching with 30% carbamide peroxide a class V cavity was prepared and restored with Tetric EvoCeram nanocomposite material. Microleakage was determined using dye method (silver nitrate) and measured on the incisal and gingival walls using stereoloupes. Results. Linear dye penetration on the incisal wall (7.25 ?m) of bleached teeth was greater than on the incisal wall in non-bleached (control group) teeth (5.75 ?m) but with no statistically significant difference. Dye penetration on the gingival wall of bleached teeth (20.00 ?m) was greater than on the gingival wall of the control group (14.25 ?m). This difference was statistically significant (p&lt;0.05). Conclusion. Greater microleakage and inferior bond of composite material was observed in teeth bleached with internal bleaching technique (30% carbamide peroxide) compared to non-bleached teeth.
Charles Peirce’s Rhetoric and the Pedagogy of Active Learning

Abstract Although John Dewey has had the most profound effect on education, less is known about the philosophy of education of the original founder of pragmatism, Charles Peirce Using Peirce’s theory of formal rhetoric, I try to show that Peirce’s philosophy of education, when fully understood, is aligned with Dewey’s pedagogy of experiential learning, and can provide a justification for the promotion of active learning in the classroom. Peirce’s rhetoric, as one part of his logical or semiotic theory, argues that reasoning alone is not sufficient to gain knowledge, but that it must be embedded within a community of inquiry, of a certain sort. Applying this to the classroom, I argue that we, as teachers, should endeavor to create the features of a proper community of inquiry in the classroom, one that emphasizes engagement of the students in doing research rather than passively receiving information about its results.
development of the potential of SMEs – covid Subsidy for the company Krasnodwór Restaurants Katering Krystyna Lekarewicz to finance the current activity and ensure its liquidity

The project provides for a grant to Krasnodwór Restaurants Katering, which has been hit by the COVID-19 pandemic. As a result of the pandemic, turnover has decreased significantly. The grant will ensure that the company’s operations and employment are maintained for at least 3 calendar months.
PURSE-STRING SUTURES

A method of suturing a tissue opening can comprise placing a tissue-facing surface of a first pad (374), a second pad (372) and a third pad (370) over respective tissue areas adjacent to the tissue opening. The second pad (372) can be positioned on a first side of the first pad (374) and the third pad (370) can be positioned on a second side of the first pad. The first and second pads can be coupled to a suture (310), the suture forming a stitch (316, 320) over the upper surface of each of the respective pads. The suture can be stitched through an area of tissue between the first pad and the second pad, between the second pad and the third pad, and between the third pad and the first pad. A first distal portion (312) and a second distal portion (324) of the suture can be coupled to the third pad (370) for forming the purse-string suture.
The vaccine adjuvant alum inhibits IL-12 by promoting PI3 kinase signaling while chitosan does not inhibit IL-12 and enhances Th1 and Th17 responses

Alum is the principal vaccine adjuvant for clinical applications but it is a poor inducer of cellular immunity and is not an optimal adjuvant for vaccines where Th1 responses are required for protection. The mechanism underlying the inefficiency of alum in promoting Th1 responses is not fully understood. We show that aluminium hydroxide, aluminium phosphate, and calcium phosphate adjuvants inhibit the secretion of the Th1 polarizing cytokine, IL-12 by dendritic cells (DCs). Alum selectively inhibited DC expression of the IL-12p35 subunit and the inhibitory effect results from adjuvant-induced PI3 kinase signaling. To develop a more effective adjuvant for promoting cell-mediated immunity, we investigated alternative particulates and found that in contrast to alum, the cationic polysaccharide chitosan did not inhibit IL-12 secretion. A combination of chitosan and the TLR9 agonist CpG activated the NLRP3 inflammasome and enhanced secretion of IL-12 and the other key Th1 and Th17-cell polarizing cytokines. When used as an adjuvant, CpG-chitosan induced NLRP3-dependent antigen-specific Th1 and Th17 responses. A combination of alum and CpG also enhanced Th1 and Th17 responses but was less effective than CpG-chitosan. Therefore, chitosan is an attractive alternative to alum in adjuvants for vaccines where potent cell-mediated immunity is required.
GLYCOSYLATED INDOLOCARBAZOLE SYNTHESIS

Tertiary alcohols containing the structural features illustrated in 3 or 4 (Scheme I) are prepared by reacting at least one diazo carbonyl compound, (e.g., 1 in Scheme I) and at least one allylic alcohol (e.g., 2 in Scheme I) in a coupling reaction run under conditions that produce carbene or carbenoid intermediates from the diazo-containing substrate such as transition metal catalysis or either thermal or photochemical decomposition. In some preferred embodiments, Rh2(OAc)4 is employed to catalyze the coupling reaction. In Scheme I R represents a substituent comprised of any number and combination of the elements H, C, N, S, Si, O, Cl, Br, I, and F. Indolocarbazoles (e.g., 7 in Scheme II) are prepared by coupling of diazo carbonyl compounds (e.g., 5 Scheme II) and biindoles (e.g., 6 in Scheme II). Indolocarbazoles are furanosylated (e.g., 7 in Scheme II) with acetals (e.g., 8 in Scheme II) or their open chain congeners (e.g., 9 in Scheme II) under conditions known to promote acetal exchange or formation, such as protic or Lewis acids. Furanosylated indolocarbazoles (e.g., 10 in Scheme II) are also prepared via ring contraction of pyranosylated indolocarbazoles (e.g., 11 in Scheme II) under conditions know to effect oxidation and benzylic acid type rearrangements, and pyranosylated indolocarbazoles (e.g., 11 in Scheme II) are prepared via ring expansion of the furanosylated congeners (e.g., 10 in Scheme II).
Intraocular lens power calculation for eyes with an axial length greater than 26.0 mm: Comparison of formulas and methods

To evaluate and compare the accuracy of formulas and methods for calculating the intraocular lens (IOL) power for eyes with an axial length (AL) greater than 26.0 mm.Ein-Tal Eye Center, Tel-Aviv, Israel.Retrospective case series.The postoperative refraction results in myopic eyes with an AL over 26.0 mm were compared with the predicted refractions calculated using standard formulas (Holladay 1, SRK/T, Hoffer Q, and Haigis) with optical IOL constants, User Group for Laser Interference Biometry constants, and an AL-adjustment method and using new-generation formulas (Barrett Universal II, Holladay 2, and Olsen).In 76 (71.7%) of 106 eyes, the IOL was 6.0 diopters (D) or more (Group A) and in 30 eyes (28.3%) was less than 6.0 D (Group B). In Group A, the SRK/T, Hoffer Q, Haigis, Barrett Universal II, Holladay 2, and Olsen methods met the benchmark criteria of having a prediction error of ±0.5 D in at least 71.0% of eyes and ±1.0 D in 93.0% of eyes. In Group B, only the Barrett Universal II formula and the Holladay 1 and Haigis formulas using the AL-adjusted method met those criteria.When selecting IOLs for high and extreme myopia, choosing appropriate formulas and methods can yield accurate refractive results that meet benchmark criteria.No author has a financial or proprietary interest in any material or method mentioned.
Bent member and an apparatus and method for its manufacture

A bent member having a bent portion with an extremely small bend radius is manufactured by supporting a rectangular tube by a first support means disposed at a first position A while performing relative feeding of the rectangular tube in its lengthwise direction, locally heating the rectangular tube by a heating means disposed at a second position B, cooling the rectangular tube by a cooling means disposed at a third position C, and at the time of working, applying a shear force to the heated portion of the rectangular tube with a shear force applying means 14 disposed in a downstream region D by moving the device 14 two-dimensionally or three-dimensionally simultaneously in the feed direction of the rectangular tube and in a direction generally parallel to a transverse cross section in the lengthwise direction of the rectangular tube which was heated by the heating means.
SELF SANIFICATION

PURCHASE OF PPE AND SERVICES FOR THE SANITISATION OF WORKING ENVIRONMENTS TO QUICKLY DETECT AND REDUCE THE SPREAD OF POSSIBLE INFECTIONS. THESE EXPENSES ARE INCURRED IN ORDER TO SAFEGUARD THE HEALTH OF STAFF ON THE FARM WHILE ENSURING THE SMOOTH RUNNING OF THE COMPANY’S PRODUCTION ACTIVITIES AFTER COVID-19.
Perioperative Blood Transfusion and Postoperative Outcome in Patients with Crohn’s Disease Undergoing Primary Ileocolonic Resection in the “Biological Era”

Perioperative blood transfusion has been shown to be associated with inflammatory response and immunosuppression. Patients receiving blood transfusion may have an increased risk for developing postoperative morbidities. The impact of blood transfusion on the postoperative recurrence of Crohn's disease (CD) has been controversial. The aim of this study was to assess the effect of blood transfusion on postoperative outcomes in CD in the current biological era.This historical cohort study involved data collection and analysis of CD patients who underwent the index ileocolonic resection in our institution between 2000 and 2012. Postoperative complications were compared between the transfused and nontransfused patients. The effects of perioperative blood transfusion on postoperative complications and disease recurrence were analyzed with both univariate and multivariate analyses.A total of 318 patients were included in the study, and 52 of them (16.5 %) received perioperative blood transfusion. Blood transfusion was found to be associated with an increased risk of postoperative infectious and noninfectious complications both in univariate (P < 0.001 for each) and multivariable analyses (infectious complications: odds ratio [OR] = 8.73, 95 % confidence interval [CI] 2.85-26.78, P < 0.001; noninfectious complications: OR = 3.64, 95 % CI 1.30-10.18; P = 0.014). In addition, the Cox regression model indicated that blood transfusion was associated with both surgical (hazard ratio [HR] = 3.43, 95 % CI 1.92-6.13; P < 0.001) and endoscopic (HR = 2.08, 95 % CI 1.38-3.14; P < 0.001) CD recurrence following the index surgery.Adverse outcomes after perioperative blood transfusion for the primary ileocolonic resection for CD resemble findings in surgery for other diseases. The presumed immunosuppressive effect of blood transfusion did not confer any protective effect on disease recurrence.
Capacity increase of Caçarola II Restaurant and Creation of local accommodation unit in Freguesia Novo – Figueira da Foz

Strengthening the capacity of the company Esteves & Martins, Lda. in the development of new services, by increasing the capacity of an existing establishment (Caçarola II Restaurant) passing the number of seats from 110 to 150 and the creation of a local accommodation unit with 9 rooms.
PROFILE SYSTEM

The present invention relates to a profile system, comprising a first profile element designed as a horizontal profile, a second profile element designed as a vertical profile, a profile connector element and at least one U-shaped fastener to connect the two profile elements together using the profile connector element. The first profile element has guide channels which extend in the longitudinal direction of the profile to receive the two leg parts of the profile connector element. In addition, the first profile element has at least one fastening channel for receiving the at least one fastener in a force-locked or frictionally interlocking manner. Seen in cross-section, the second profile element has a U-shaped cut-out for receiving, in parts, the profile connector element. The profile connector element, in the main part thereof, and the second profile element, in the base of the U-shaped cut-out therein, each have at least one mounting port, corresponding to the fastening channel of the first profile element, through which the fastener can be guided. According to the invention, at least the second profile element is designed in multiple parts and has at least a first profile shell portion, arranged towards the interior, and a second profile shell portion, arranged towards the exterior, with the profile shell portions being connected to one another and thermally insulated from one another by at least one insulating element, and with a connection, which is flexible under shear stress, between the profile shell portion arranged towards the interior and the profile shell portion arranged towards the exterior being ensured at least in the second profile element by means of the insulating element itself or by the connection of the insulating element to one of the two connected profile shell portions.
The ICMJE's definition of authorship is illogical and unethical

In recent years there have been many revelations about ghost authors, who contribute to publications but are not credited, and guest authors, who do not contribute but are credited. Most medical and many other journals adhere to the authorship standards set by the International Committee of Medical Journal Editors (ICMJE), which were designed in part to combat the phenomena of ghost and guest authorship. However, the current criteria set for authorship by the ICMJE have their own problems.

Imagine that Andrew, Michael, and Chris decide to collaborate on some research. Andrew has had a brilliant idea for a study, and he and Chris carry it out successfully. Michael writes a paper based on their results and analysis, and Chris checks and corrects it. All three approve the final draft. They are aware that their paper is of great importance, so they decide to submit it to the BMJ . All goes well until they reach the authorship statement stage of the submission process, where they must agree with the statement, “We all meet the definition …
Participation of LD seating at foreign trade fairs II.

The aim of the submitted project is the participation of LD seating s.r.o. at selected foreign trade fairs. The purpose of the project is to present the company at the exhibition stand of these fairs, the related provision and transport of the stand, the transport of exhibits to the place of realisation by an external supplier and the creation of related promotional materials. The project will be implemented between 2019 and 2022 a.
New finance for energy efficiency measures in public buildings

NEW FINANCE project is designed to improve the lives of people by driving leadership in energy innovation. 
More than 4500 municipalities in the MED area have committed to increasing energy efficiency and use of renewable energy sources on their territories by joining the Covenant of Mayors initiative; our task is to showcase proven implementation models they use and the results they achieved to help accelerate new investment and savings in and beyond the MED area allowing for cross-country comparisons. 
The project will take a step towards making energy efficiency investment easier by increasing the confidence of key decision makers from public and finance sector to find and apply working strategies for mobilisation of private funding and better use of ESI funds.
In order to reach this goal, the project will focus on effective replication and smart networking activities equally involving stakeholders from public and private sector whilst capitalizing on a number of previous and ongoing similar initiatives.
IBUPROFEN-CAFFEINE COMBINATIONS

This invention relates to pharmaceutical compositions for use in the treatment of pain and inflammation in mammals, including humans, by administering compositions comprising (i) an analgesically and anti-inflammatory effective amount of a salt of (S)-ibuprofen substantially free of (R)-ibuprofen wherein the salt is selected from (S)-ibuprofen-(S)-lysine and (S)-ibuprofen-(R)-lysine; and (ii) an amount effective in the enhancement of pain relief of caffeine.
Inheritances, Intergenerational Transfers, and the Accumulation of Health

This paper considers the mechanisms behind a positive correlation between inheritances and health. First, there may merely be a correlation: those from families with enough wealth to provide an inheritance tend to have better health. Second, financial resources could be used to purchase inputs to health. Third, bequests may signal a stronger interest in one's child. This reminder to the child could improve their emotional well-being. On average, the positive correlation suggests merely correlation. However, among subsets of the population, particularly men and those expecting to receive an inheritance, there is a causal relationship likely driven by the third mechanism.
SURGICAL RETRACTOR

The invention relates to a surgical retractor, in particular for retracting a divided sternum, comprising a first retention mechanism (12) and a second retention mechanism (14) which each have a retracting arm (16, 18) with at least one retention element (26) held thereon, a holding mechanism (28) for holding the retention mechanisms (12, 14) on each other, and a drive mechanism (46) with which the distance between the retracting arms (16, 18) along a retraction distance (20) can be changed in order to transfer to a retracting position. In order to provide a retractor of this type that is compact and easy to handle, the invention proposes that the retention mechanisms (12, 14) each have a holding arm (30, 32) connected to the respective retracting arm (16, 18), wherein both holding arms (30, 32) couple to the drive mechanism (46) and, by means of the latter, are displaceable relative to each other, and relative to the holding mechanism (28), along a displacement direction (20).
METHOD AND DEVICE FOR TREATING WASTEWATER CONTAINING ORGANIC MATTER AND/OR WET WASTE CONTAINING ORGANIC MATTER, IN PARTICULAR FOR TREATING SANITARY WASTEWATER IN TRAINS

The invention relates to a method for treating wastewater containing organic matter and/or wet waste containing organic matter, in particular for treating sanitary wastewater (15) in trains. According to the invention, the method comprises the following steps: a) cleaning the wastewater containing matter and/or the wet waste containing organic matter, in particular the sanitary wastewater (15) in trains, in a bioreactor (20), b) feeding the wastewater (24) at least partially purified in the bioreactor (20) into a conditioning system (30), c) at least partially separating phases of the partially purified wastewater (24) in the conditioning system (30), d) obtaining a liquid fraction and a solid fraction of the at least partially purified wastewater (24).
Schedule performance measurement based on statistical process control charts

In a job–shop environment, achieving a schedule that is on target is difficult due to the dynamism of factors affecting the system. In this paper the Shewart's Individuals control chart is applied to a scheduling process for the purpose of measuring schedule performance. The charts are applied to monitor the deviations of actual from scheduled process times for jobs on a process machine. Data transformation operations are used to counter the negative effects of non–normal data. The proposed methodology enables a scheduler study the variations between scheduled and actual outcomes, seek ways of eliminating these variations and check if process improvements have been effective. SPC charts have not been used to measure schedule performance in a job shop setting, so this paper uniquely contributes to research within the field.
MICROCAPSULE POWDER

The invention relates to hydrophobed powders consisting of microcapsules and/or nanocapsules, obtained as follows: (a) an aqueous solution of at least one polymer is dispersed in oil in the presence of a W/O emulsifier at a temperature above the gel point of the polymer solution, (b) the dispersion is cooled to a temperature below the gel point by mixing, (c) the microcapsules or nanocapsules thus produced are isolated by decantation, and (d) the oily dispersion obtained according to step c) is laced with an oil-absorbing auxiliary agent. The invention also relates to the method for producing the hydrophobed powder and the use thereof in cosmetic and/or pharmaceutical preparations and detergents and cleaning agents.