SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Eco-Friendly modification of bitumen (ecomobi) - recycling end of life tyres into an efficient bitumen modifier

Tecnofilm is an Italian SME with 44 years of experience in the thermoplastic industry. Our project, ECOMOBI, was granted the Seal of Excellence label in the last Phase 1 call with a score of 13.28; we have thus decided to resubmit it. Through ECOMOBI we plan to develop an innovative cost-effective eco-compound for the modification of bitumen. 

Bitumen has a wide range of uses, namely road construction. In order to confer it the necessary characteristics for this use, bitumen is currently modified through the use thermoplastic elastomers. However, these elastomers are expensive and confer low aging resistance, making them even less cost-effective. There is a need for bitumen modifiers that can offer the same quality properties as thermoplastic elastomers, but reducing the cost and increasing the lifespan of the end products.

On the other hand, Europe searches to promote solutions for the recycling of tyres. Across Europe, 5.7M tonnes of tyres are stockpiled in landfills, and recently the biggest tyre dump in Europe caught fire, with the subsequent damage to the environment and human health. However, currently only 17% of Europe's end of life tyres are recycled. 

ECOMOBI brings forward the development of a solution for bitumen modification using end of life tyres: RD PRENE. Through the commercialization of RD PRENE, Tecnofilm would have an annual revenue of 10M € in 2022. Its innovative formulation and extrusion process have managed to match the quality of thermoplastic elastomers. The increased elasticity of the bitumen modified with RD PRENE confers a 50% longer lifespan to end products than current alternatives, reducing the maintenance and replacement needs and derived costs. Moreover, due to the use of tyre powder in its composition, RD PRENE is 57-26% less expensive than current alternatives and can lead an average  bitumen production site to save 15% annually. We offer a solution to the user's needs and tackles the European tyre-recycling concern.
COMPRESSION GARMENT

The present invention relates to compression garments comprising a pants section with a rear side, wherein the rear side comprises an insert, a first side section and a second side section, the first side section being connected to a first side of the insert, the second side section being connected to a second side of the insert, wherein the insert is adapted to extend over at least part of both buttocks of a wearer, and wherein the insert consists of a seamless knitted fabric. The present invention, further, relates to related methods for determining measurement information and methods for manufacturing compression garments.
Is approximate numerical judgment truly modality-independent? Visual, auditory, and cross-modal comparisons

The numerosity of any set of discrete elements can be depicted by a genuinely abstract number representation, irrespective of whether they are presented in the visual or auditory modality. The accumulator model predicts that no cost should apply for comparing numerosities within and across modalities. However, in behavioral studies, some inconsistencies have been apparent in the performance of number comparisons among different modalities. In this study, we tested whether and how numerical comparisons of visual, auditory, and cross-modal presentations would differ under adequate control of stimulus presentation. We measured the Weber fractions and points of subjective equality of numerical discrimination in visual, auditory, and cross-modal conditions. The results demonstrated differences between the performances in visual and auditory conditions, such that numerical discrimination of an auditory sequence was more precise than that of a visual sequence. The performance of cross-modal trials lay between performance levels in the visual and auditory conditions. Moreover, the number of visual stimuli was overestimated as compared to that of auditory stimuli. Our findings imply that the process of approximate numerical representation is complex and involves multiple stages, including accumulation and decision processes.
Umsetzung von Prozessinnovationen bei der Herstellung technologisch fortschrittlicher, dichter, abflussfreier Stahlbetontanks mit Anwendung auf der Klärgrube.

Das Projekt zielt darauf ab, die Wettbewerbsfähigkeit des Antragstellers zu erhöhen und die Anwendung von Innovationen in seinen Aktivitäten durch Diversifizierung der Anlage zu erhöhen. Eine Prozessinnovation wird bei der Herstellung technisch verbesserter Stahlbetontanks für Klärgruben umgesetzt, die zuvor nicht vom Antragsteller hergestellt wurden. Das Projekt wird eine selbstfahrende Umform- und Vibrationsmaschine in kontinuierlicher Verformungstechnologie für die Herstellung von Stahlbetonelementen von 4000 x 2000 x 1 300 mm und kleiner mit der Möglichkeit der Verstärkung von Betonelementen mit Stahlstangen zusammen mit einer kompletten elektronischen und computergesteuerten Steuerung, ausgestattet mit elektrischer Installation, Hydrauliksystem mit Antiatheseöl und einem Satz von drei Formen erwerben. Alle Teile zusammen bilden ein Ganzes, und die auf ihnen hergestellten Produkte zeichnen sich durch hohe Qualität und unvergleichliche Dichtigkeit mit der Konkurrenz aus.
Chain-to-chain competition under the cap-and-trade scheme

This paper considers two competing supply chains under the cap and trade scheme, each of which consists of one manufacturer and one retailer. In the vertical direction, the manufacturer is the leader of Stackelberg game; in the horizontal direction, there is a parallel competition about the product greening level between manufacturers. We solve and analyze the equilibrium solutions of a centralized supply chain (CSC) and a decentralized supply chain (DSC) respectively. The results show that the greening level of CSC is higher than that of DSC, and the corresponding price is lower than that of DSC. That means the CSC has greater competitive advantage. Numerical analysis reveals that higher emissions reduction investment coefficient leads to lower greening level and higher retail price; higher greening level competition degree leads to lower greening level, whereas affects retail price differently in CSC and DSC.
Targeting the adaptive capacity of prostate cancer through the manipulation of transcriptional and metabolic traits

The composition and molecular features of tumours vary during the course of the disease, and the selection pressure imposed by the environment is a central component in this process. Evolutionary principles have been exploited to explain the genomic aberrations in cancer. However, the phenotypic changes underlying disease progression remain poorly understood. In the past years, I have contributed to identify and characterise the therapeutic implications underlying metabolic alterations that are intrinsic to primary tumours or metastasis. In CancerADAPT I postulate that cancer cells rely on adaptive transcriptional & metabolic mechanisms [converging on a Metabolic Phenotype] in order to rapidly succeed in their establishment in new microenvironments along disease progression. I aim to predict the molecular cues that govern the adaptive properties in prostate cancer (PCa), one of the most commonly diagnosed cancers in men and an important source of cancer-related deaths. I will exploit single cell RNASeq, spatial transcriptomics and multiregional OMICs in order to identify the transcriptional and metabolic diversity within tumours and along disease progression. I will complement experimental strategies with computational analyses that identify and classify the predicted adaptation strategies of PCa cells in response to variations in the tumour microenvironment. Metabolic phenotypes postulated to sustain PCa adaptability will be functionally and mechanistically deconstructed. We will identify therapeutic strategies emanating from these results through in silico methodologies and small molecule high-throughput screening, and evaluate their potential to hamper the adaptability of tumour cells in vitro and in vivo, in two specific aspects: metastasis and therapy response. CancerADAPT will generate fundamental understanding on how cancer cells adapt in our organism, in turn leading to therapeutic strategies that increase the efficacy of current treatments.
Reliable Protocol for Shear Wave Elastography of Lower Limb Muscles at Rest and During Passive Stretching

Development of shear wave elastography gave access to non-invasive muscle stiffness assessment in vivo. The aim of the present study was to define a measurement protocol to be used in clinical routine for quantifying the shear modulus of lower limb muscles. Four positions were defined to evaluate shear modulus in 10 healthy subjects: parallel to the fibers, in the anterior and posterior aspects of the lower limb, at rest and during passive stretching. Reliability was first evaluated on two muscles by three operators; these measurements were repeated six times. Then, measurement reliability was compared in 11 muscles by two operators; these measurements were repeated three times. Reproducibility of shear modulus was 0.48 kPa and repeatability was 0.41 kPa, with all muscles pooled. Position did not significantly influence reliability. Shear wave elastography appeared to be an appropriate and reliable tool to evaluate the shear modulus of lower limb muscles with the proposed protocol.
GLASS MOLDING SYSTEM AND RELATED APPARATUS AND METHOD

A glass molding system and a method of making glass articles using the glass molding system are disclosed. The glass molding system includes an indexing table, a plurality of enclosures arranged along the indexing table, and a plurality of stations defined on the indexing table such that each of the stations is selectively indexable with any one of the enclosures. At least one radiant heater is arranged in each of the enclosures. A radiation reflector surface and a radiation emitter body are arranged in each of the enclosures. The radiation emitter body is between the at least one radiant heater and the radiation reflector surface and has a first surface in opposing relation to the at least one radiant heater and a second surface in opposing relation to the radiation reflector surface.
Climate Change Course Impacts on the Individual, their Future, and Interactions with Others

This report explores the impacts a university climate change course has on those enrolled in the course. The research quantitatively measures and compares opinions, attitudes, and knowledge among groups, then qualitatively explores the responses of the group to identify course impacts. The results show reasons people enroll in the course, how they have or will change their behaviors, how they communicate with others about the topic, identifies a range of open response categories, and how they apply the knowledge and solutions outside of the course. Tables display detailed responses. Conducting more research and analysis can expand this area of research.
Strong decay of low-lyingS11andD13nucleon resonances to pseudoscalar mesons and octet baryons

Partial decay widths of the nucleon resonances $S_{11}(1535)$, $S_{11}(1650)$, $D_{13}(1520)$ and $D_{13}(1700)$ to the pseudoscalar mesons and octet baryons are studied within a chiral constituent quark model. The effects of the configurations mixing between the states $|N^{2}_{8}P_{M}>$ and $|N^{4}_{8}P_{M}>$ are considered, taking into account the breakdown of the $SU(6)\otimes O(3)$ symmetry. In addition, possible contributions of the strangeness components in the $S_{11}$ resonances are investigated. Experimental data for the partial decay widths of the $S_{11}$ and $D_{13}$ resonances are well reproduced. Predictions for coupling constants of the four nucleon resonances to pseudoscalar mesons and octet baryons, crucial issues in the photo- and hadron-induced meson production reactions, are reported.
Using expectations and satisfaction to measure the frontiers of efficiency in public universities

Students’ satisfaction with their university and course is of fundamental importance to retain students and promote their positive worth-of-mouth. The objective of this research is to analyse the level of efficiency of Portuguese public universities, according to the expectations and satisfaction of their students. To accomplish the objective, this article uses data envelopment analysis methodology. As our unit of analysis, we selected the faculties making up the universities researched. The analytical input came from the expectations of 1669 students regarding their study programme and their universities. The outputs stem from their satisfaction with their study programmes and their universities. We conclude that university practices do not currently guarantee efficiency. We also observe that efficiency in the relationship between expectations and general satisfaction with the study programme does not represent efficiency in the relationship between expectations and general satisfaction with the universi...
Reconstitution of chromosome replication and epigenetic inheritance

A PubMed search for ‘epigenetic’ identifies nearly 35,000 entries, yet the molecular mechanisms by which chromatin modification and gene expression patterns are actually inherited during chromosome replication — mechanisms which lie at the heart of epigenetic inheritance of gene expression — are still largely uncharacterised.   Understanding these mechanisms would be greatly aided if we could reconstitute the replication of chromosomes with purified proteins.  The past few years have seen great progress in understanding eukaryotic DNA replication through the use of cell-free replication systems and reconstitution of individual steps in replication with purified proteins and naked DNA. We will use these in vitro replication systems together with both established and novel chromatin assembly systems to understand: a) how chromatin influences replication origin choice and timing, b) how nucleosomes on parental chromosomes are disrupted during replication and are distributed to daughter chromatids, and c) how chromatin states and gene expression patterns are re-established after passage of the replication fork.  We will begin with simple, defined templates to learn basic principles, and we will use this knowledge to reconstitute genome-wide replication patterns.  The experimental plan will exploit our well-characterised yeast systems, and where feasible explore these questions with human proteins.  Our work will help explain how epigenetic inheritance works at a molecular level, and will complement work in vivo by many others.  It will also underpin our long-term research goals aimed at making functional chromosomes from purified, defined components to understand how DNA replication interacts with gene expression, DNA repair and chromosome segregation.
A Study to assess the Physical Growth in Children of Working and Non-Working Mothers

Children of today are the citizens of tomorrow. Childhood is the period of rapid change in developmental, social, emotional, cognitive and linguistic abilities of the child. The mother continues to be the main person who cares for children. Employment of women has created number of problems for the development of children. A comparative study was conducted to assess the physical growth in children of working and non- working mothers in a selected community, Ludhiana, Punjab with objectives: To assess the physical growth in children of working and non- working mothers, To compare the physical growth in children of working and non-working mothers, To assess and compare the relationship of physical growth in children of working and non-working mothers with selected demographic variables and to prepare pamphlets. A non-experimental, comparative study was conducted in selected community of Ludhiana. The target population was children (3–5 years) of working and non- working mothers. 60 children were selected by purposive sampling technique. Data was collected by using self structured proforma. Data was analyzed by using descriptive and inferential statistics and presented through tables and figures. Findings revealed that majority of children of Non- working mothers had normal physical growth as compared to children of working mothers. While comparing the physical growth in children of working and non-working mothers three parameters of physical growth that is weight for age, height for age and mid arm circumference were found statistically significant and body mass index was found statistically non significant. In demographic variables mother's age, child's gender, birth order, and Type of Family had an impact on Weight for age, birth order had some impact on height for age. Family income had an effect on mid arm circumference and mother's age had impact on body mass index of children.
The role of the induction zone on the detonation–turbulence linear interaction

Detonation–turbulence linear interaction analysis extends the non-reactive shock–turbulence analog by considering geometrical scaling of the noise with respect to the half-reaction distance. The analysis emphasizes the effect of structure in energizing selective frequencies, and determining acoustic amplification in the farfield. Natural frequencies are determined as eigenvalues of the inviscid non-forced interaction problem. They modify postshock energy spectra by supporting resonant amplification, and cast light on the role of the activation energy on the detonation–turbulence interaction. Detonations with higher activation energies amplify smaller scales by resonant amplification. An analysis of the bifurcation parameters reveals a strong link between detonation overdrive and acoustic attenuation. The damping is correlated with the subcritical nature of the characteristic solutions for high overdrives. For detonation conditions on the stability boundary, a larger overdrive supports a weaker resonant pe...
FLUSHING TANK

The present invention pertains to the field of the sanitary, chemical and food industries and essentially relates to a flushing tank in which the lid and/or the body comprises an opening connected to a perforated guiding tube in which a cleaning brush is provided. According to other embodiments, the brush is autonomous or is removably connected to the mechanism for actuating the release valve. The brush is thus continuously cleaned by the through-flowing water or any other solution contained in the tank, which eliminates the needs for a distinct tank filled with water.
Exploring molecular determinants of charged disordered protein interactions, phase separation and function from the test-tube to the cell

Biological molecular recognition is centred around the structure-function paradigm, involving interfacial complementary shapes and non-covalent forces. Intrinsically disordered proteins (IDPs), constituting up to 40% of the proteome, evade the structure-function paradigm, owing to their lack of persistent structure. Despite some IDPs forming folded complexes, numerous IDPs form disordered complexes stabilized by multivalent interactions. An extreme example is the recently discovered disordered high-affinity complex formed by two highly charged IDPs, the nucleosome binding linker histone (H1) and its nuclear chaperone prothymosin-alpha (ProTa), both key regulators of chromatin-structure and -function. IDPs are also often implicated in liquid-liquid phase separation (LLPS) driven assemblies that facilitate numerous biochemical interactions. The specificity question in IDPs becomes particularly pertinent for such charge driven disordered interactions and associated LLPS processes considering the great abundance of such highly charged disordered stretches in our proteome. Specific physiological function of most IDP interactions and associated LLPS processes imply an important role of specificity, albeit encoded differently from folded proteins. Only a multidisciplinary study spanning several complexity regimes, which is currently lacking, can uncover such altered specificity. I hypothesize that physiologically, ProTa/H1 interaction plays out in LLPS-driven heterochromatin assemblies leading to transcriptional regulation. I will probe ProTa/H1 interactions and phase behaviour with a set of systematically designed variants in incrementally complex milieu, from the test-tube to the cell, to reveal how the sequence dictates interactions and phase behaviour in-vitro and attribute a given function in-cell. This will shed light on specificity determinants of interaction and function for such highly charged IDPs.
Validation of a novel diagnostic biomarker for dry eye syndrome based in nucleotides detection

Scientists of our company invented a method for diagnosing and monitoring the effectiveness of dry-eye syndrome treatment. The invention is related to a method for diagnosing the Dry Eye syndrome in patients and monitoring the effectiveness of the treatment, by measuring the concentration of a molecule called diadenosine tetraphosphate dinucleotide (Ap4A). Ap4A is an intracellular signal molecule that is produced due to harsh environmental factors. According to our studies published since 2002, Ap4A is released from the corneal epithelium, stimulating tear production and is a physiological modulator of tear secretion. Most importantly we discovered that levels of Ap4A are up to 5 times above normal levels in patients with Dry Eye compared to patients with normal lacrimation. This increase is even higher in Dry Eye individuals with low tear production. In these cases the Ap4A is increased over 100 fold. Following this discovery we patented a method to measure the concentrations of Ap4A of tear samples from patients in order to determine its presence, which is abnormally high in the case of Dry Eye syndrome. According to this method it is possible objectively to confirm or to discount the presence of this pathology. The diagnostic method of this invention comprises: detection by means of the high-pressure liquid chromatography (HPLC) technique of the Ap4A molecule, for the purposes of the calculation of which use will be made of a standard sample of Ap4A of commercial origin and of known concentration; and the use of a luminometric method for the detection and quantification of the Ap4A dinucleotide by means of the use of luciferin luciferase. We already effectively tested the method in vitro and in vivo on Dry Eye animal models. Recently we made a successful first stage trial in a small number of patients. Our future actions include the collaboration with industry partners, expert on biomarkers, in order to create a small detection kit.
Analysis on Polygonal Wear of Automotive Tire Based on Lateral Vibration of Tire Tread

The nonlinear characteristic of tire's grounding friction being considered,a dynamic model of the polygonal wear of tire is established by using dynamical LuGre friction model based on the lateral vibration of tire tread.Then the stability of the system is analyzed,and the self-excited vibration of the tire is proved to be a kind of stable periodic vibration caused by Hopf bifurcation of system.The results show that the polygonal wear of tire is a typical nonlinear self-excitation vibration phenomenon which is related to lateral vibration of tire tread and the polygonal number is equivalent to the ratio of the lateral vibration frequency of tire tread to the rotational frequency of tire.The ranges of speed and toe-in-angle which can motivate self-excited vibration are given through simulation.The results show that the model can interpret the formation mechanism of the polygonal wear,and provide a theoretic foundation to reduce or eliminate the tire's self-excited vibration.