SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
IN SITU SULPHUR REMELTER

Sulphur is produced as a by-product during the extraction of natural gas from the earth and is usually stored in solidified form in large blocks near the extraction location. In order to conveniently transport quantities of sulphur, it may be melted. The present invention provides a heating element for use in a solid sulphur remelter, the heating element comprising a series of mutually spaced melting pipes forming a heating plane, a top steam header pipe and a bottom condensate header pipe at respective ends of the melting pipes and communicating therewith, the top steam header pipe having an inlet for receiving steam therein for distribution into the melting pipes and the bottom condensate header pipe being adapted for collecting condensate and discharging of the condensate through an outlet formed therein and a hot nose pipe attached adjacent and in front of the bottom condensate header pipe and having a steam inlet and a condensate outlet for melting sulphur in front of the bottom condensate header pipe.
Characterising the spatial organisation and regulation of the wnt receptor complex in stem cells and cancer

Wnts are a family of secreted glycoproteins that control maintenance and proliferation of stem cell reservoirs during tissue homeostasis and regeneration after injury. Deregulated Wnt signalling due to mutations in important signalling intermediates is strongly linked to disease. The complex molecular mechanisms mediating Wnt-induced cell responses are therefore of wide interest and the underlying protein interactions provide attractive drug targets, particularly in regenerative medicine and cancer treatment. 

The earliest events that occur after Wnts bind their receptors at the cell surface, such as receptor endocytosis and recruitment of cytoplasmic effectors, are decisive for downstream gene activation but the underlying mechanisms by which these events process and tune the Wnt signal remain poorly understood. The key objective of this proposal is to resolve critical molecular events that drive initiation of the Wnt cascade in stem and cancer cells. By using a novel tool developed in the Maurice laboratory to detect endogenous Wnt-bound complexes, The Applicant will focus on the following central objectives: 

1. To elucidate Wnt receptor localisation in sub-cellular compartments
2. To examine the regulation of Wnt receptor trafficking and turnover in response to Wnt signalling
3. To investigate how cancer cells exploit Wnt receptor trafficking to drive tumour growth

To meet these objectives, The Applicant will be trained to employ an integrated approach combining biochemistry and genome editing in intestinal organoid cultures with advanced imaging including immuno-electron microscopy to develop a unique set of tools to study Wnt receptor trafficking and turnover at the endogenous level. The expected insights will be vital to understand how pathway activation is controlled and for strategies to interfere with Wnt signalling in disease.
The construction and thinking on entrepreneurship pilot classes in vocational education

In 2010, Wuxi Institute of Technology begun to build the pilot classes of innovation and entrepreneurship aiming at training and educate comprehensive talents with certain sense of innovation and entrepreneurship. The pilot classes combine the innovation and entrepreneurship education with the talent cultivation targets highly, while taking the form of small classes and mentoring. Taking the venture pilot classes of the marketing professional as an example, this paper gives a comprehensive review of the construction of entrepreneurship classes in the last three years from aspects of formation, development and achievement. Moreover, the success factors of entrepreneurship education are also summarized.
Substrate unit and electronic device

According to one embodiment, a substrate unit includes an electronic circuit substrate which includes a first width dimension portion, and a second width dimension portion continuous with the front direction side of the first width dimension portion. A first concave portion is formed on the first direction side of the first width dimension portion and a second concave portion is formed on the second direction side of the first width dimension portion in the electronic circuit substrate. The substrate unit includes a heat sink which includes a first side frame portion fixed to the first width dimension portion from the first concave portion, a second side frame portion fixed to the first width dimension portion from the second concave portion, and a sink main body portion continuous from the first side frame portion to the second side frame portion.
The rise and fall of assertive community treatment?

Assertive community treatment is one of the most researched and clinically replicated of all community mental health teams. It is clearly defined with established scales to measure its model fidelity. In the last decade its earlier claims to substantially reduce hospitalization have not been replicated in research studies. This inconsistency has generated considerable controversy. A careful systematic review and meta-regression analysis was conducted of 64 trials including 7,819 patients. The review included measures of model fidelity and hospitalization outcomes. Variation in reduced hospitalization was found to be mainly due to variation in control service practice but model fidelity to team organization principles was also associated with reduced hospitalization. Low caseloads and specified ACT staffing, however, had no effect at all on outcome. 'Ordinary CMHTs' share most of the organizational aspects of ACT and appear to deliver equal outcomes with much reduced resources. The value of investing in high fidelity ACT teams must, therefore, be in doubt.
A RETAINER LOCK

The present invention relates to locking devices and in particular to apparatus and methods for securing components to a bicycle frame (60). A first exemplary embodiment of a locking device (100) includes a first retainer (120), a second retainer (170) and a key (190). The first retainer (120) includes a coupler (124) which is configured to couple with a coupler (196) on key (190). The first retainer (120) further includes a first radial surface (130) having a frusto-conical configuration. The second retainer (170) includes a tab member (174) configured to prevent the rotation of the second retainer (170) relative to the bicycle frame (60). In a second exemplary embodiment of a locking device (300) includes a first retainer (320), a sleeve (360), a second retainer, and a key. The first retainer (320) includes a coupler (324) which is configured to couple with a coupler on the key. Sleeve (360) is configured to at least partially receive first retainer (320) and includes a tab member (364) configured to prevent the rotation of the sleeve relative to the bicycle frame (60).
Translating the Genomic Architecture of Breast Cancer into Clinical Applications

The genetic alterations in breast cancer have in recent years been studied through a variety of techniques: analysis of alterations in individual oncogenes and tumor suppressor genes; gene expression profiling of both messenger RNA and microRNA; global analysis of DNA copy number changes; and most recently, whole-genome sequence analysis. Analysis of the association between genetic alterations and gene expression profiles with prognosis and response to specific treatments will lead to improved possibilities for patient-tailored treatment. Russnes et al. now add an additional view on the complex genetic makeup of breast carcinomas by developing algorithms that can be used to subclassify tumors based on their patterns of genome-wide DNA copy number gains and losses, which vary from very simple (only a few gains and losses) to complex. The algorithms provide indices that can be used in conjunction with results from other genetic analyses to subclassify breast cancer, with the aim of defining subgroups of patients that differ with respect to prognosis and response to therapy.
Jumps and Nonjumps in Multigraphs

In this paper we consider an extremal problem regarding multigraphs with edge multiplicity bounded by a positive integer $q$. Given a family $\mathscr{F}$ of $q$-multigraphs, define $ex(n,\mathscr{F})$ to be the maximum number of edges (counting multiplicities) that a $q$-multigraph on $n$ vertices can have without containing a copy of any $F \in \mathscr{F}$ (not necessarily induced). It is well known that $\tau(\mathscr{F}) = \lim_{n \to \infty} ex(n,\mathscr{F})/\binom{n}{2}$ exists for every family $\mathscr{F}$ (finite or infinite). Let $\mathscr{T} = \{\tau(\mathscr{F}) : \mathscr{F} \textrm{ is a family of $q$-multigraphs}\}$. We say the number $\alpha$, $0 \leq \alpha \alpha$, then $\alpha' \geq \alpha + c$. The Erdos--Stone theorem implies that for $q=1$, every $\alpha \in [0,1)$ is a jump. The problem of determining the set of jumps for $q \geq 2$ appears to be much ha...
Development and industry transfer of new techniques: full characterization of vector ultrashort pulsed laser beams

The main objective of this proposal is to take advantage of the expertise of the host company and the experienced researcher in different fields of ultrashort laser pulses technology, in order to develop new techniques for the measurement of the time-dependent arbitrary polarization of the pulses, simultaneously with their spatiotemporal dependence. It is foreseen that the research will derive into patents, and industry transfer of the products. Within the project, the temporal measurement of pulses in other regions of the spectrum (as near UV, XUV) will also be investigated.
The polarization measurement will be based in the measurement of the spectral interferometry between the two polarization components of the pulse, together with a complementary measurement of one component. The spatiotemporal measurement is performed scanning a fibre coupler while also acquiring spectral interferences. It will be investigated the way of combining both techniques to measure the full dependence of vector beams (pulses with arbitrary polarization). In both cases, the expertise of the host in the d-scan technique and industry transfer will be relevant for development of the project.
The research will be carried out in excellent infrastructures owned by the host. The experienced researcher will be trained not only in new experimental skills, but also in the process of patenting, project managing, study of market, product development and financial issues. Altogether, it will allow him to boost his career in terms of future opportunities. The host will also benefit from the results of the action and the new products will put the European Photonics Industry in an advantageous position on a global scale in the area of ultrashort laser pulses metrology.
Action Plan: Joint European Connections / Transboundary Transport for the Islands

Between Corsica and Sardinia, there are no regular maritime connections that allow to develop economic, cultural and cooperation relations with continuity and fair costs. The GEECCTT-Iles action project takes on this Programme challenge to optimise and enhance relations between the islands of the cooperation area by creating an inter-insular connection tool to meet the needs of Corsica, Sardinia and Elba, all historically linked. Through analysis, definition and constitution, GEECCTT creates an EGTC - European Territorial Cooperation Group, a legal EU entity for the shared management of cross-border transport services between the islands. The creation of the EGTC will define the conditions for the management of regular cross-border maritime links between the islands, as well as the legal and administrative procedures for resolving the implications of this management at the Member State and European Commission level. GEECCTT will thus create the conditions for the development of innovative sustainable services for cross-border mobility between the islands through port nodes, also by facilitating the conditions for integration with the multimodal transport system to improve connections with TEN-T networks. The result is the setting up of conditions to create and manage jointly the relationships between Corsica and Sardinia—linked to the TEN-T systems—with an innovative perspective of cross-border continuity. The general population, businesses (especially SMEs) and the island and cooperation area communities will benefit from the result of this link that completes the upper Tyrrhenian area.
Device and method for controlled charging of a secondary battery

A device and method is provided that can detect overcharge reliably by separating heat generated by internal resistance and heat chemically generated upon overcharging in a secondary battery. Based on the temperature of the secondary battery (10) detected every first predetermined time by a battery temperature detection section (12), a temperature gradient operation section (14) calculates a temperature gradient indicating a temperature increase per unit time for every second predetermined time that is longer than the first predetermined time. When a temperature gradient determination section (16) determines that the temperature gradient is larger than a predetermined temperature gradient threshold, which is preset according to the charged state of the secondary battery,  N  times in a row (where  N  is a natural number), a fully charged state of the secondary battery is detected.
Eight-element MIMO Antenna with Tightly-arranged Pairs for 5G Mobile Terminal

In this paper, a compact eight-element MIMO antenna is presented for 5G mobile terminal applications. The proposed antenna structure consists of four blocks, and each block has two tightly arranged inverted F antennas (IFAs). The edge-to-edge distance between the two IFAs is only 1 mm. Inductor is used to improve the port isolation in each block. The size of the block is 27.4 mm × 4.5 mm. There is no ground clearance between the antenna and the platform. The simulated results show that the bandwidth of the proposed MIMO antenna is 260 MHz, which is sufficient for the 3400-3600 MHz band.
Climate resilient orphan crops for increased diversity in agriculture

Agrobiodiversity is a vital subset of biodiversity and is the result of the interaction between the environment, genetic resources and management systems used by culturally diverse people. It is a crucial prerequisite for ecologically and economically sustainable agricultural systems and is an important tool for ecological intensification. The aim of CROPDIVA is to reinforce agrobiodiversity on different levels and along distinct geographic and socio-economic areas. The activities of CROPDIVA are clustered around five connected research work packages and three pillars, each with a set of specific objectives: i) promotion of six key underutilised arable crops: oats, hull-less barley, triticale, buckwheat, faba bean and lupin; ii) creation of value chains for selected underutilised crops ; and iii) study of the socio-economic impact of project results. The concept of CROPDIVA is an innovative challenge driven approach based on the promotion of underutilised crops in sustainable cropping systems and new regional value chains. Project activities will focus on the following major challenges: improved resilience of cropping systems, alignment of the economic and social needs of farmers with ecological goals as well as marketing of new food/non-food products meeting consumer demands. The results gathered in CROPDIVA will not be descriptive, but will be used for innovative solutions along the entire food and non-food chain to enable biodiversity management on all levels, including diversifying the use of genetic resources, crop production systems, new food/non-food products, market opportunities while satisfying producers and investigated consumer requirements.
Role of Silver Salts in Palladium-Catalyzed Arene and Heteroarene C–H Functionalization Reactions

Silver carboxylate salts are widely used as additives in palladium-catalyzed C–H functionalization reactions. However, the role of these silver additives is often not fully understood. This paper describes an investigation of the role of AgOPiv in the stoichiometric activation of C6F5H at a well-defined PdII complex as well as in the PdII-catalyzed oxidative dimerization of 2-alkylthiophenes. Both in situ NMR spectroscopy and H/D exchange studies of the reactions of C6F5H implicate a role for AgOPiv in the C–H cleavage event, generating Ag–C6F5 as an intermediate. The catalytic studies show similar trends despite the different conditions and substrates, suggesting that AgOPiv promotes a similar metalation of the thiophene in the catalytic transformations. This proposal is supported by DFT calculations, which show energetically feasible pathways for concerted metalation–deprotonation of both 2-methylthiophene and pentafluorobenzene at [Ag(OPiv)]2. These studies suggest that initial metalation of C–H substr...
Smart digital transformation of villages in the Alpine Space

Alpine space rural communities are deprived of highly needed jobs, good provision of services as well as a favourable climate for enterprenuership and social innovation, which result in a brain drain. Digitalization is a promising approach to counter the situation. However the digital divide between rural and urban areas has even increased in the last years. A smart village (SV) approach for mountain areas could unlock the potential of local actors to make their region a more attractive place to live and work. The project aims to apply a SV approach and bring together - in so called Regional Stakeholder Groups (RSGs) - policy makers, business, academia and civil society in a quadruple helix approach (4H) to improve the framework for innovation through new forms of stakeholder involvement facilitated by Information and Communication Technologies (ICT). This includes the following elements, involving the RSGs on every step: 1) In regional analyses the SV ecosystem in test areas (TAs) is described (WPT1); 2) a digital exchange platform (DEP) is implemented for the exchange on the SV approach (WPT2); 3) During the project, the SV toolbox is developed in the TAs in parallel to pilot activities (PAs) in order to enhance networks and services by means of digital, telecommunication technologies, innovations and the better use of knowledge. The information will finally be combined into one transnational toolbox (WPT3); 4) recommendations are formulated to facilitate the transformation of project results into policies (WPT4).  The proposed "SmartVillages" project is a strategic initiative of EUSALP AG5 and follows an integrative, participatory approach implying a city - village dialogue. The direct beneficiaries are local/regional authorities and administrations, SMEs, public service providers, regional development agencies and NGOs which will receive a concrete guidance to implement the SV approach._x000D_
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Information added on 2020-06-01, regarding the mitigation of the effects of COVID-19 (the coronavirus pandemic that started in 2019) (English language only): The project SmartVillages provides smart solutions for rural and mountainous areas, which can contribute to the recovery from the pandemic. In the municipality of Kungota (SI) for instance, 5,000 citizens benefit from free public WLAN/WiFi points to promote their services online and advertise local products through a dedicated mobile application.
Aortic Valve Replacement Versus Conservative Treatment in Asymptomatic Severe Aortic Stenosis: The AVATAR Trial

Background: Surgical aortic valve replacement (SAVR) represents a class I indication in symptomatic patients with severe aortic stenosis (AS). However, indications for early SAVR in asymptomatic patients with severe AS and normal left ventricular function remain debated. Methods: The AVATAR trial (Aortic Valve Replacement Versus Conservative Treatment in Asymptomatic Severe Aortic Stenosis) is an investigator-initiated international prospective randomized controlled trial that evaluated the safety and efficacy of early SAVR in the treatment of asymptomatic patients with severe AS, according to common criteria (valve area ≤1 cm 2 with aortic jet velocity &gt;4 m/s or a mean transaortic gradient ≥40 mm Hg), and with normal left ventricular function. Negative exercise testing was mandatory for inclusion. The primary hypothesis was that early SAVR would reduce the primary composite end point of all-cause death, acute myocardial infarction, stroke, or unplanned hospitalization for heart failure compared with a conservative strategy according to guidelines. The trial was designed as event-driven to reach a minimum of 35 prespecified events. The study was performed in 9 centers in 7 European countries. Results: Between June 2015 and September 2020, 157 patients (mean age, 67 years; 57% men) were randomly allocated to early surgery (n=78) or conservative treatment (n=79). Follow-up was completed in May 2021. Overall median follow-up was 32 months: 28 months in the early surgery group and 35 months in the conservative treatment group. There was a total of 39 events, 13 in early surgery and 26 in the conservative treatment group. In the early surgery group, 72 patients (92.3%) underwent SAVR with operative mortality of 1.4%. In an intention-to-treat analysis, patients randomized to early surgery had a significantly lower incidence of primary composite end point than those in the conservative arm (hazard ratio, 0.46 [95% CI, 0.23–0.90]; P =0.02). There was no statistical difference in secondary end points, including all-cause mortality, first heart failure hospitalizations, major bleeding, or thromboembolic complications, but trends were consistent with the primary outcome. Conclusions: In asymptomatic patients with severe AS, early surgery reduced a primary composite of all-cause death, acute myocardial infarction, stroke, or unplanned hospitalization for heart failure compared with conservative treatment. This randomized trial provides preliminary support for early SAVR once AS becomes severe, regardless of symptoms. Registration: URL: https://www.clinicaltrials.gov ; Unique identifier: NCT02436655.
AUTOMATIC ANSWER MODE PROVISION FOR SOME TELEPHONE NETWORK CALLS

A telephone-network signals calls to destination terminal equipment by either of two categories of ON/OFF ringing signal: one category, called a short-ring and having ON periods less than a time-interval T, is used to signal calls intended for automatic answering; the other, having ON periods longer than T, is used to signal "telephony" calls which need the attention of a person from the start of the end-to-end connection. Upon receipt of a ringing signal, equipment at the terminal will seek assured detection of any prescribed short-ring cadence and then provide prompt automatic answering, but will stop seeking short-ring detection if an ON period exceeds T and then rely on an audible or other telephony alerting signal to elicit manual answering. The network may be instructed in 3 ways to signal a call with a short-ring: if the call originates from some designated terminal or network facility, or when number dialling has been preceded by a special pre-code (e.g. involving characters * and #), or when the number dialled has been selected from a plurality of numbers allocated to the receiving end-connection.