SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
The TreadWheel: A Novel Apparatus to Measure Genetic Variation in Response to Gently Induced Exercise for Drosophila

Obesity is one of the dramatic health issues affecting developed and developing nations, and exercise is a well-established intervention strategy. While exercise-by-genotype interactions have been shown in humans, overall little is known. Using the natural negative geotaxis of Drosophila melanogaster, an important model organism for the study of genetic interactions, a novel exercise machine, the TreadWheel, can be used to shed light on this interaction. The mechanism for inducing exercise with the TreadWheel is inherently gentle, thus minimizing possible confounding effects of other stressors. Using this machine, we were able to assess large cohorts of adult flies from eight genetic lines for their response to exercise after one week of training. We measured their triglyceride, glycerol, protein, glycogen, glucose content, and body weight, as well as their climbing ability and feeding behavior in response to exercise. Exercised flies showed decreased stored triglycerides, glycogen, and body weight, and increased stored protein and climbing ability. In addition to demonstrating an overall effect of TreadWheel exercise on flies, we found significant interactions of exercise with genotype, sex, or genotype-by-sex effects for most of the measured phenotypes. We also observed interaction effects between exercise, genotype, and tissue (abdomen or thorax) for metabolite profiles, and those differences can be partially linked to innate differences in the flies' persistence in maintaining activity during exercise bouts. In addition, we assessed gene expression levels for a panel of 13 genes known to be associated with respiratory fitness and found that many responded to exercise. With this study, we have established the TreadWheel as a useful tool to study the effect of exercise in flies, shown significant genotype-specific and sex-specific impacts of exercise, and have laid the ground work for more extensive studies of how genetics, sex, environment, and aging interact with exercise to influence metabolic fitness in Drosophila.
MedWet-Reseau CODDE - Reseau MedWet d'information et conaissance pour le developpement durable des ecosystemes hydriques

The Mediterranean Wetlands Initiative (Med-Wet) of the Ramsar Convention, a permanent network of collaboration and provision of scientific knowledge to all Mediterranean countries, has launched the Med -Wet/CODDE project under the INTERREG IIIC programme in order to provide regions with a tool that will allow decision-making on regional development activities based on the knowledge of water-related ecosystems that exist in their territory, the benefits these bring to people and the pressures they need to be protected against. Wetlands are important ecosystems providing a number of services to human society, such as flood control, water storage and purification, climate control and development opportunities including fisheries, agriculture, tourism and many others. Sustainable development depends on the knowledge of decision-makers about the existence of environmental resources in any region. By securing the provision of easy-to-use knowledge on the ecosystems and the functions and services they provide to society, as well as the needs they have for appropriate management through long-term planning, decision makers can address priority issues so that long-term viability of the ecosystems can be secured, coupled with sustainable generation of income and employment for local people. Overall objective / Objectif général The MedWet/CODDE project will mobilise existing MedWet network partners in Greece, France, Italy and Portugal and exchange knowledge with Estonia in order to build on the extensive know-how and information already existing in the network. It will provide an innovative web-based tool that allows all users to access easy-to-use information on the location, ecological characteristics and socio-economic importance of water-related ecosystems. By incorporating Remote Sensing and Satellite Imaging it will also provide a state-of-the-art tool for all involved stakeholders to monitor and assess the current status and trends of such ecosystems, and to adapt their development strategies to keep them healthy and to maximise the long-term benefits they bring to society. Expected results / Résultats attendus The MedWet/CODDE project will establish a web-based database in which the basic information on all Mediterranean wetlands will be stored on-line. The project will keep information regularly updated, drawing from satellite images, interactive maps and other remote sensing techniques. This will allow decision makers to base their planning on factual information about the existence, values and threats to important ecosystems in their territory. The project will put particular emphasis on developing components that show clearly the socio-economic importance of such ecosystems, including aspects such as cultural heritage, land use, traditional uses and socio-economic indicators, so that the trends and effects of sustainable development decisions can be assessed. Seminars and workshops aimed at relevant stakeholders will ensure that regional players become accustomed to using the tool and will secure its long-term operation.
An Efficient Multiple-Loop Sensor Configuration Applicable for Undisciplined Traffic

This paper presents an effective multiple-inductive-loop pattern suitable for heterogeneous and less lane-disciplined traffic and its performance evaluation. Vehicle detection system based on conventional inductive loops works well only for lane-based and homogeneous traffic. A multiple-loop system for sensing vehicles in a heterogeneous and less lane-disciplined condition has been reported recently. The scheme proposed in this paper employs a new configuration, where all the loops are connected in series, which considerably reduces the system complexity and improves reliability. Each loop has a unique resonance frequency and the excitation source given to the loops is programmed to have frequency components covering all the loop resonance frequencies. When a vehicle goes over a loop, the corresponding inductance and resonance frequency will change. The shift in frequency or its effect in any/every loop can be simultaneously monitored, and the vehicles can be detected and identified as a bicycle, a motorcycle, a car, a bus, etc., based on the signature. Another advantage of this scheme is that the loops are in parallel resonance; hence, the power drawn from the source will be minimal. A prototype multiple-loop system has been built and tested based on the proposed scheme. The developed system detected, classified, and counted vehicles accurately. Moreover, the system also computes and provides the speed of the vehicle detected using a single set of multiple loops. The accuracy of the speed measurement has been compared with actual values and found to be accurate and can be used for real-time intelligent transportation system (ITS) applications under heterogeneous and less lane-disciplined (e.g., Indian) conditions.
Drivers and feedbacks of changes in arctic terrestrial biodiversity

CHARTER aims to advance state-of-the-art (SOTA) knowledge on Arctic biodiversity change and social-ecological systems (SES) on four critical fronts: i) Feedbacks: To understand transitions in vegetation cover, energy balance and cryospheric change at centennial, decadal, and present-day time scales; ii) SES and biodiversity: To understand the effects of biodiversity changes on indigenous/local communities and traditional livelihoods, e.g. reindeer herding; iii) Modelling: To integrate biochemical/permafrost soil carbon exchange, sea ice and albedo into an Earth System Model (ESM), and incorporate these into the latest Arctic Regional Climate modeling efforts; and iv) Policy: To develop strategies supporting Arctic communities with co-benefits and synergies between adaptation, mitigation and policy implications. To accomplish these, CHARTER combines expertise from Earth System sciences, biodiversity indices and SES research. CHARTER is an ambitious effort to advance SOTA modelling of 21st century Arctic change with major socio-economic implications and feedbacks for the Cryosphere. We bring together our strongly participatory approaches that incorporate indigenous/local communities’ ways of knowing regional changes with SOTA research on circumpolar climate dynamics and long-term palaeoecological studies. CHARTER collates and processes truly transdisciplinary quantitative and qualitative empirical datasets for a holistic view that can be modeled. Arctic residents and stakeholders work alongside scientists to identify risks and viable adaptation strategies in relation to projected changes and future resilience in Arctic SESs. CHARTER combines natural sciences with ESM and participatory approaches to leverage the untapped potential for wild ungulate and livestock management to regulate global climate feedbacks through biogeoengineering. CHARTER’s results will lead to new tools and data for implementing sustainable strategies and establish public dialogue on the Arctic.
The range of stereoscopic perception: influence of binocular summation, interocular differences in optical quality and halo perception

AbstractThe study of the visual function and optical quality of the eye has become a fundamental aim in the characterization of visual performance, especially in binocular vision, as this is our natural state of visual perception and because of its importance in clinical applications. Interocular asymmetry affects visual performance, and therefore its effect on different visual functions and stereopsis is of interest. In this work, we analyse interocular differences in optical quality (higher order aberrations and Strehl ratio) on the maximum disparity (the total range of stereoscopic perception) under mesopic conditions. We also analyse the relationship between the maximum disparity and the visual-discrimination capacity (halo perception) or binocular summation. The results in normal observers show a deterioration of the range of stereoscopic perception with the interocular differences in optical quality and with a higher perception of halos. Regarding the binocular summation for the visual functions stu...
Dormer window glazing frame - has insulating mass inserted in frame angle to hold glazing also

Dormer window frame includes an insulating compound which is inserted in one of the frame components to form a mass which is used to hold the glazing and the same time fulfil an insulating function. The frame component should have means of anchoring the insulating mass in place and the mass itself should be of a rubbery or elastic consistency. The frame component is preferably an angle with connection legs for the glazing. The frame should be used in conjunction with further frames, in which case the insulation lies exposed towards the additional frame to form an insulated join between the two frames once installed.
La fisonomía lingüística de 86*RL y su relación con otros cancioneros impresos antiguos: variación y singularidad

El Cancionero de Llavia (86*RL) salió de la imprenta de los Hurus, en Zaragoza, entre 1484 y 1488 aproximadamente. Su fama se debe, sobre todo, a su reputación de cancionero pionero de los albores de la imprenta en España y a su condición de testimonio de las Coplas por la muerte de su padre de Jorge Manrique. En este artículo presentamos, en primer lugar, un corpus de ocho poemas seleccionados entre los incluidos en el Cancionero de Llavia y, asimismo, el grupo de impresos antiguos —realizados desde finales del siglo XV hasta principios del XVI— que también conservan alguno de los mismos textos. A través del cotejo, para cada uno de los poemas en cuestión, entre las versiones de 86*RL y las de los otros cancioneros impresos hemos podido recabar datos de interés lingüístico —de distinta naturaleza (grafemática, léxica, morfológica, sintáctica)— que, por un lado, permiten contribuir a la descripción de la lengua del Cancionero de Llavia y, por el otro, ponen en evidencia variantes y lecciones únicas de dicho incunable con respecto al resto de la documentación impresa.
Desarrollo e implementación de un producto médico innovador basado en compuestos de amonio cuaternario como sustancia activa para la desinfección rápida de superficies pequeñas y de difícil acceso

«Programa Numer_reference_aid_programme: SA.42799(2015/X), destinado a ayudas públicas: Artículo 28 del Reglamento n.º 651/2014 de la Comisión" El objeto del proyecto es el desarrollo y la aplicación de un producto sanitario innovador basado en compuestos de amonio cuaternario como sustancia activa para la desinfección rápida de zonas pequeñas y de difícil acceso. — Análisis de vías de desarrollo alternativos, — Detalle y evaluación del camino elegido, — Preparación de un modelo financiero detallado, — Identificación y cartografía de los procesos empresariales clave, — Búsqueda y establecimiento de contactos con el proveedor de tecnología, — Ayuda en el desarrollo de documentación funcional o técnica, — Asistencia en las negociaciones con el proveedor de tecnología, — Asesoramiento en el proceso de preparación de un acuerdo de compra de tecnología, — Análisis de riesgos de la aplicación de innovaciones, — asesoramiento y asistencia en el ámbito de la experimentación, — Asesoramiento y formación en la plena aplicación de las innovaciones, — Seguimiento de los efectos de la aplicación, — Análisis del impacto de la tecnología en el medio ambiente, — Asesoramiento en la gestión de la propiedad intelectual, — Desarrollo de una estrategia de marketing, — Asesoramiento sobre el desarrollo de los recursos humanos Como resultado de la implementación de servicios de asesoramiento, será posible ponerse en contacto con el proveedor de tecnología utilizada para implementar un dispositivo médico innovador en la oferta de ventas del solicitante.
My active and healthy aging

Background
We propose a holistic view of interrelated frailties: cognitive decline, physical frailty, depression and anxiety, social isolation and poor sleep quality, which are a major burden to older adults and social and health care systems. Early detection and intervention are crucial in sustaining active and healthy ageing (AHA) and slowing or reversing further decline.

Aims and Relevance
The main aim of my-AHA is to reduce frailty risk by improving physical activity and cognitive function, psychological state, social resources, nutrition, sleep and overall well-being. It will empower older citizens to better manage their own health, resulting in healthcare cost savings. my-AHA will use state-of-the-art analytical concepts to provide new ways of health monitoring and disease prevention through individualized profiling and personalized recommendations, feedback and support.

Approach
An ICT-based platform will detect defined risks in the frailty domains early and accurately via non-stigmatising embedded sensors and data readily available in the daily living environment of older adults. When risk is detected, my-AHA will provide targeted ICT-based interventions with a scientific evidence base of efficacy, including vetted offerings from established providers of medical and AHA support. These interventions will follow an integrated approach to motivate users to participate in exercise, cognitively stimulating games and social networking to achieve long-term behavioural change, sustained by continued end user engagement with my-AHA.

Scale and Sustainability
The proposed platform provides numerous incentives to engage diverse stakeholders, constituting a sustainable ecosystem with empowered end users and reliable standardised interfaces for solutions providers, which will be ready for larger scale deployment at project end. The ultimate aim is to deliver significant innovation in the area of AHA by cooperation with European health care organizations, SMEs, NGOs.
Innovadora radiografía industrial como una oportunidad para el desarrollo de Indutronic sp. z o.o.

El objeto del proyecto y el objetivo principal del proyecto es introducir en la actividad actual del solicitante un innovador proceso de diagnóstico de servicio conocido y aún no utilizado en Polonia a través de la compra de los modernos sistemas de inspección TruView Prime A X-Ray. La demandante es consciente de que, sin un mayor desarrollo relacionado principalmente con la compra de equipos de diagnóstico modernos, sin aumentar el empleo, no podrá competir eficazmente en el mercado de servicios especializados como la reparación de productos electrónicos industriales. El resultado de las observaciones del mercado es información sobre la demanda constantemente creciente e insaturada de servicios de servicio y diagnóstico. La compra de nuevos activos fijos y la introducción de la innovación de procesos y productos (servicios innovadores de diagnóstico de dispositivos) permitirán al solicitante ser capaz de satisfacer las necesidades del mercado y así desarrollar su negocio. Como resultado del proyecto, el perfil de los destinatarios de los servicios existentes no cambiará significativamente. Sin embargo, la demandante tiene previsto prestar un servicio innovador a un grupo más amplio de clientes en Polonia y en el extranjero.
Archwire vibration and stick-slip behavior at the bracket-archwire interface

It is unknown whether or not intraoral vibrations affect stick-slip behavior at orthodontic bracket-archwire interfaces. In this study, we evaluated bracket-archwire stick-slip behavior as a function of ligation method and archwire vibration.In-vivo archwire vibrations were measured to obtain frequencies and amplitudes for ex-vivo testing. A piezoresistive accelerometer ligated to the maxillary right canines of 6 subjects transduced the intraoral vibrations. All subjects gave informed consent to participate. Amplitude and frequency of the vibrations were quantified and used in a bench-top friction testing apparatus. Active and passive ligation methods were compared for 9 vibration scenarios. The amount of time to move the bracket along a stainless steel wire was recorded in 90 trials. Analysis of variance and post-hoc tests were used for statistical analyses of the data.During carrot biting, orthodontic wire vibrations had a mean frequency of 98 Hz and a peak-to-peak mean amplitude of 151 mV. The bench-top stick-slip measurement trials containing medium (150 mV) and high (190 mV) amplitude vibrations had significantly less friction (ln, s), 4.81 ± 2.08 and 4.67 ± 2.00, respectively, than those subjected to low (110 mV) amplitudes, 5.80 ± 1.39 (P = 0.04). There were no significant differences between passive and active ligation methods.Amplitudes of archwire vibrations affect stick-slip behavior at the bracket-archwire interfaces.
Hyperpolarised mr technologies and molecular probes as alternatives for conventional metal-containing contrast agents for mri examinations

Recently, the European Medicines Agency (EMA) and the U.S. Food & Drug Administration (FDA) recommended suspension and warning labels for Gadolinium (Gd)-bearing CAs (GBCA) used in magnetic resonance imaging (MRI). This decision, although made in the absence of any clinical evidence, relates to potential major health concerns resulting from long-term accumulation of Gd containing species in patients’ bodies. This sends a clear message that we need to carefully consider the necessity of each contrast injection in individuals undergoing an MRI scan. However, for a number of diagnostic procedures, such as tumour characterisation, the use of a CA is often essential. The accumulation of Gd in different organs (including the brain) and GBCA-related diseases requires the scientific community to seek radically new alternatives. The AlternativesToGd vision is to identify and validate radically new compounds and technologies as alternatives to GBCAs. The new compounds and technologies developed in this proposal will be tested in animal models of disease and the most promising ones selected for further clinical development. The expected outcomes should radically impact the field, likely leading to a paradigm shift in MR-based diagnosis and thus being highly beneficial to society. The AlternativesToGd consortium will develop a new class of MRI CAs that will be metal-free, safe, and completely eliminated from the human body after the MRI exam. The agents will consist of small endogenous molecules, in which nuclear spins will be hyperpolarised to ensure high sensitivity to MR detection, even at very low doses. A major challenge and risk arises from the rapid decay of the hyperpolarised (HP) state. As enabling technologies, AlternativesToGd focuses on three leading and innovative hyperpolarisation techniques and on unique agents showing HP state lifetimes that are sufficiently long to enable diagnostic contrast-enhanced MRI approaches with so far unobtained sensitivity.
SCREW VACUUM PUMP

The invention relates to a screw vacuum pump comprising screw rotors (12, 14) disposed in a suction chamber (10). The screw rotors (12, 14) are each supported by means of two bearing elements (20) in the pump housing and comprise a ratio of rotor length (I) to rotor axis spacing (d) that is greater than 3.0. The screw rotors (12, 14) further comprise a variable pitch, at least 7 turns, and an integral compression ratio of at least 4.5. The pitch after half of the turns is less than twice the pitch on the pressure side rotor outlet (24).
Return to work: A case of PTSD, dissociative identity disorder, and satanic ritual abuse

This case study investigated an intervention that enabled an individual with Posttraumatic Stress Disorder (PTSD), Dissociative Identity Disorder (DID), and satanic ritual abuse to return to work after discharge from psychiatric inpatient treatment. The Occupational Questionnaire [88] revealed past difficulties in organization, awareness of time, communication, cooperation, frustration tolerance, competition, stress management, goal setting, and amnesia resulting in incomplete tasks and sporadic attendance at work. The Role Checklist [72] identified alters valuing work and employed in the past. The Modified Interest Checklist [70] identified running as an interest that 24 alters shared. Based on the initial evaluations, three times a week treadmill running was used as an intervention that built work skills (as measured by the Clerical Work Sample of the Valpar Component Work Sample Series [97]) necessary to sustain gainful employment upon discharge. After intervention, this individual improved in awareness of time, stress management, and goal setting abilities and was less amnestic as per the Occupational Questionnaire [88] and four additional alters expressed an interest in work according to the Modified Interest Checklist [70].