SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Traumi toracici: strategia diagnostica e terapeutica

Le principali cause di trauma toracico, aperto o chiuso, sono rappresentate in Francia dagli incidenti stradali e dalle cadute da grandi altezze e si integrano generalmente nel contesto di politraumi. Il coinvolgimento del torace durante un meccanismo di decelerazione improvvisa è soprattutto causa di lesioni di tipo traumatico chiuso: contusione di organi solidi e rottura di organi cavi. I criteri clinici di gravità in un paziente con trauma toracico sono: distress respiratorio acuto e/o sofferenza circolatoria ed esistenza di più di due fratture costali, nonché elementi legati alle condizioni del paziente. Il primo trattamento in un paziente cosciente è un’analgesia efficace il più precocemente possibile per migliorare i parametri ventilatori. La titolazione della morfina rimane la modalità analgesica di riferimento nel dolore severo. Una sedazione con ketamina può essere necessaria in caso di mobilizzazione dolorosa del paziente o prima di eseguire una procedura invasiva (riduzione di lussazione, ecc.). La valutazione della lesione toracica al momento del ricovero prevede una radiografia del torace e/o un’ecografia pleuropolmonare, che consentono in particolare di stabilire se sia necessario un drenaggio urgente. L’esame tomodensitometrico con iniezione di mezzo di contrasto è l’esame standard per la diagnosi delle lesioni toraciche e in particolare delle lesioni aortiche. La toracotomia emostatica è indicata in un paziente in shock emorragico dovuto a un emotorace persistente e attivo nonostante l’attuazione di un drenaggio toracico. La via d’ingresso sarà anterolaterale, destra o sinistra, a seconda della sede dell’emotorace. La combinazione di ventilazione non invasiva e di analgesia locoregionale è considerata una strategia terapeutica ottimale nel paziente cosciente. Il posizionamento di uno stent in radiologia interventistica è il trattamento di prima linea per le rotture traumatiche dell’aorta.
Species-specific PCR detection of the food-borne pathogen Vibrio parahaemolyticus using the irgB gene identified by comparative genomic analysis

Vibrio parahaemolyticus is an enteric pathogen, which can cause acute gastroenteritis in humans after consumption of raw or partially cooked seafood, and specific molecular markers are necessary for its accurate identification by PCR methods. In the present study, 23 protein-coding sequences were identified by the comparative genomics method as V. parahaemolyticus-specific candidate markers. We targeted the irgB gene (vp2603), coding for iron-regulated virulence regulatory protein IrgB, in order to develop a PCR method for the detection of V. parahaemolyticus. PCR specificity was identified by amplification of 293 V. parahaemolyticus templates and by the loss of a PCR product with 11 strains from other Vibrio species and 35 non-Vibrio bacterial strains. The PCR assay had the 369-bp fragment and the sensitivity of 0.17 pg purified genomic DNA from V. parahaemolyticus. Furthermore, a multiplex PCR assay for the detection of total and virulent strains of V. parahaemolyticus was developed by targeting irgB, tdh and trh genes. These data indicated that the irgB gene is a new and effective marker for the detection of V. parahaemolyticus. In addition, this study demonstrates that genome sequence comparison has a powerful application in identifying specific markers for the detection and identification of bacterial pathogens.
The Effect of Age, Race, Pregnancy and Treatment Facility on the Follow-up Biopsy Rate for Atypical Squamous Cells, Cannot Exclude High-grade Squamous Intraepithelial Lesion (ASC-H) and High-grade Squamous Intraepithelial Lesion (HSIL) Diagnoses at Two New Orleans Teaching Hospitals

changes were found in 55 cases. Interestingly, no transformation zone was found in 20 cases. We have observed that the incidence of dysplasia in patients below 40 is 64.3% vs. 53.8% (pZ0.147) in patients above 40 years. If we combine the dysplastic cases, the difference is more significant, of these 309 cases, 179 (57.9%) cases showed dysplastic changes including CIN-1, CIN-2 or CIN-3. There were 67 cases with high risk HPV DNA Testing. HPV DNA was positive in 39 of dysplastic cases [(14 CIN-1), (24 CIN-2 or CIN-3)] and negative in 5 (1 CIN-1 & 4 CIN2/3) cases; for non-dysplastic cases (benign, inflammation, koilocytic), 14 cases were HPV positive and 9 cases negative (Sensitivity 73.6%, Specificity 64.3%, PPV 88.6%, NPV 39.1%, pZ0.012). Conclusions: We concluded that cases diagnosed as ASC-H should be followed-up with caution as they are strongly associated with dysplasia (57.9%) especially CIN2/3 (38.83%,high grade dysplasia). Reflex HPV testing is an important predictor of dysplasia with 88.63% positivity in dysplastic cases. Reactive changes and koilocytic atypia can result in the reactive atypia. Sampling errors, such as lack of transformation zone and sampling of the non-representative areas are the most common factors of discrepancy between the pap smear and subsequent biopsy. Close follow-up of ASC-H cases is recommended.
Corrosion properties of Zn-Ni-P alloys in neutral model medium

Abstract The presented work reports on the peculiarities of the anodic behavior, corrosion resistance and protective ability of electrodeposited Zn-Ni-P alloys with a different composition in a model corrosion medium of 5% NaCl. Three characteristic coating types have been investigated using experimental methods such as potentiodynamic polarization (PD) technique and polarization resistance (Rp) measurements. In addition, X-ray diffraction (XRD) analysis as well as scanning electron microscopy (SEM) coupled with an Energy-dispersive X-ray (EDAX) device were applied to determine the differences in the chemical composition and surface morphology which appeared as a result of the corrosion treatment. The data obtained are compared to those of electrodeposited pure Zn coatings with identical experimental conditions demonstrating the enhanced protective characteristics of the ternary alloys during the test period in the model medium. The influence of the chemical and phase composition of the alloys on its corrosion resistance and protective ability is also commented and discussed.
Assessment of water quality and impact of effluents from fertilizer factories to the Lakhya River

A study was carried out in Polash and Ghorasal Urea fertilizer factories to assess the impact of effluent on water quality of the Lakhya River. Comprehensive waste water sampling by grab sampling method and flow measurement by float velocity method were carried out for five weeks (one sample per week) at five sampling stations at Polash and Ghorasal Urea fertilizer factories during June to July, 2007. Water quality samplings by grab sampling method were also carried out for five weeks (one sample per week) at four stations in the Lakhya River at the same time and River flows on the period of October 2006 to September 2007 were collected from Institute of Water Modelling. Effluents at both the factories and water sample from selected points in the river were analysed for pH, temperature, DO, BOD5, COD, NH3-N, NH4-N, TS, TSS, and TDS during June to July, 2007 at the Environmental Engineering Laboratory of Bangladesh University of Engineering and Technology, Bangladesh. The results showed that the effluents were alkaline while the level of DO, BOD5, COD, NH3-N, NH4-N, TS, TSS, and TDS relatively high and 17425-20012 kg/day Ammonia load discharged from fertilizer factories into the Lakhya River. The upstream water was near to neutral pH (average pH, 7.66 ± 0.102) with high dissolved oxygen but low in the levels of the other parameters. The river water after the effluent receiving points was basic (average pH, 8.16 ± 0.08) and the levels of other parameters were high due to heavy pollution load especially Ammonia discharged from fertilizer factories. The results suggested that water in the river was polluted and not good for human consumption. It is therefore recommended that the disposal of improperly treated or untreated wastes should be stopped to save the river water from further deterioration.

	 

	Key words: Industrial effluents, Impact, river water, pollution, water quality.
Development and Implementation of Monitoring System for Management of Virtual Resource Based on Cloud Computing

본 논문에서는 개방 시스템 기반 가상 자원 모니터링 시스템을 CPU, 메모리, 디스크, 네트워크 부분으로 세분화 하고 각각 모듈화하여 설계 및 구현하였다. 설계한 시스템을 구현하기 위해 Windows, Linux, Xen 운영체제를 이용하였고, 구현 언어로는 C++를 사용하였다. 그리고 시스템의 구조는 기능 업그레이드 및 추가 등의 확장성을 고려하여 가능한 기능별로 모듈화 하여 클라우드 컴퓨팅 환경에서 적용 가능한 클라우드 컴퓨팅 가상 자원 모니터링 시스템을 구현하였다. 본 논문에서 설계 및 구현한 클라우드 컴퓨팅 가상 자원 모니터링 시스템의 동작성 검사를 위해 테스트베드를 구축하여 Xen, ESX 하이퍼바이저 운영체제에서 테스트 한 결과 실시간으로 CPU, 메모리, 디스크, 네트워크 정보를 정상적으로 모니터링 함을 확인 하였다. In this paper, for this open system-based virtual resource monitoring system was designed. Virtual resources, CPU, memory, disk, network, each subdivided into parts, each modular implementation. Implementation results in real time CPU, memory, disk, network information, confirmed the results of monitoring. System designed to implement the Windows, Linux, Xen was used for the operating system, implementation language, C++ was used, the structure of the system, such as the ability to upgrade and add scalability and modularity by taking into account the features available in cloud computing environments applicable to cloud computing, virtual resource monitoring system has been implemented.
CIRCUIT AND METHOD FOR DRIVING BULK CAPACITANCE OF AMPLIFIER INPUT TRANSISTORS

Amplifier circuitry includes an input stage having a transconductance stage including first and second input transistors (60A) and a first tail current source, gates of the first and second input transistors being coupled to first and second input signals, respectively. A bulk electrode capacitance driver (15) includes third and fourth input transistors and first and second associated cascode transistors (111A) and a second tail current source coupled to the sources and bulk electrodes of the third and fourth input transistors and to the bulk electrodes of the first and second input transistors. The gates of the third and fourth input transistors are coupled to the first and second input voltage signals, respectively, and the gates of the first and second cascode transistors are coupled to the second and first input voltage signals, respectively.
Regulation of electron transport in microalgae

Unicellular algae are characterized by an extreme flexibility with respect to their responses to environmental constraints. This flexibility probably explains why microalgae show a very high biomass yield, constitute one of the major contributors to primary productivity in the oceans and are considered a promising choice for biotechnological applications. Flexibility results from a combination of several factors including fast changes in the light-harvesting apparatus and a strong interaction between different metabolic processes (e.g. respiration and photosynthesis), which all take place within the same cell. Microalgae are also capable of modifying their photosynthetic electron flow capacity, by changing its maximum rate and/or by diverting photogenerated electrons towards different sinks depending on their growth status. In this review, we will focus on the occurrence and regulation of alternative electron flows in unicellular algae and compare data obtained in these systems with those available in vascular plants. This article is part of a Special Issue entitled: Regulation of Electron Transport in Chloroplasts. ►The light-induced electron flow aliment both ATP and NADPH production in the chloroplast. ►In most cases, ATP and ADPH are produced in a ratio that is not sufficient for CO 2 assimilation. ►Alternative electron flow processes may adjust the ATP and reducing power stoichiometries. ►These processes must be tightly regulated to avoid an excessive reduction of the quantum yield of photosynthesis.
Gas hydrates in low water content gases: Experimental measurements and modelling using the CPA equation of state

Abstract In this communication, new experimental data are reported for the water content of methane and two synthetic gas mixtures in equilibrium with hydrates at pressures range from 5 to 40 MPa and temperature down to 251.65 K. The measurements have been made on equilibrated samples taken from a high-pressure variable volume hydrate cell using a new analyser based upon tuneable diode laser absorption spectroscopy (TDLAS) technology. A statistical thermodynamic approach, with the Cubic-Plus-Association equation of state, is employed to model the phase equilibria. The hydrate-forming conditions are modelled by the solid solution theory of van der Waals and Platteeuw. The thermodynamic model was used to predict the water content of methane and synthetic gases in equilibrium with gas hydrates.
METHOD FOR PREPARING AL2O2 COATING ON SURFACE OF SILICON -NITRIDE -CUTTING TOOL BY USING PVD,AND COMPOSITE COATING METHOD

A method for preparing an aluminum-oxide single-layer coating or multi-layer coating on the surface of silicon-nitride ceamic cutting tool by using a Physical Vapor Depositon (PVD) process. There are two methods for preparing the aluminum-oxdie coating by using the PVD techonology: one is depositing an aluminum-oxide layer through reactive sputtering of Al target by using a bipolar pulse power source and a Dual Magnetron Sputtering (DMS) technology in the O 2 atmosphere or Ar-O 2 mixed atmosphere; the other one is sputtering, by using DMS technology in the Ar atmosphere or Ar-O 2 mixed atmosphere, an aluminum-oxide ceramic target conductive doping, and then preparing the aluminum-oxide coating. With the two methods, a single-layer aluminum-oxide coating, a nitride and aluminum-oxide composite coating, or a multi-layer or nano composite coating obtained by alternately depositing nitride and alumimum oxide is prepared, the aluminum-oxide being ±-Al 2 O 3 , ²-Al 2 O 3 , ³-Al 2 O 3 , or amorphous Al 2 O 3 . The hard nitride coating in the multi-layer composite aluminum-oxide coating comprises a two-element nitride coating, a three-element nitride coating, multi-element nitride coating, or a multi-layer composite thereof of a nano coating.
A Performance Degradation Tolerable Cache Design by Exploiting Memory Hierarchies

Performance degradation tolerance (PDT) has been shown to be able to effectively improve the yield, reliability, and lifetime of an electronic product. The focus of PDT is on the particular performance degrading faults (pdef) that only incur some performance degradation of a system without inducing any computation errors. The basic idea is that as long as the defective chips containing only the pdef can provide acceptable performance for some applications, they may still be marketable. Critical issues of PDT to be addressed include the portion of the pdef in a faulty chip and their induced performance degradation. For a typical cache design, most of the possible faults are not pdef. In this brief, we propose a cache redesign method, called PDT cache, where all functional faults in the data-storage cells of a cache (major part of the cache) can be transformed into pdef. By transforming this large number of faults into pdef, a faulty cache becomes much more likely to be still marketable. The proposed design exploits the existing hardware resources and the inherent error resilience scheme to reduce the incurred hardware overhead. The logic synthesis results show that the incurred hardware overhead is only 6.29% for a 32-kB cache. We also evaluate the induced performance degradation under various fault densities using the CPU2000 and CPU2006 benchmark programs. The results show that for a 32-kB cache design, when the fault density is <1%, only 0.31% performance degradation is incurred. In addition, the scalability of the PDT cache is also evaluated. The results show that a smaller hardware overhead is required for a larger cache, and the performance degradation is independent of the cache associativity and can even be smaller for a larger cache under a given fault density.
Cooperative intelligence in swarms of enzyme-nanobots

In nature, systems composed of self-propelling agents display complex behaviors such as signal interpretation, propagation, amplification and engage in collective motion mediated by interactions between different agents and their environment. Examples range from swarming bacteria to schooling fish and flocking birds. These self-organized systems have served as an inspiration for researchers seeking to achieve complexity in artificial systems composed of synthetic agents. A class of agents that has recently been demonstrated is of synthetic nanomachines (nanobots) that can self-propel thanks to the conversion of chemical energy, harvested from the environment, into motion. While most of the artificial nanobots have been explored at individual level, their collective emergent behavior, arising from inter-particle interactions through chemical and hydrodynamic fields, and through environment mediated interactions is yet to be properly studied. Understanding collective effects will be especially useful in biologically relevant environments, where a number of applications for these nanobot systems have been envisioned. 

i-NANOSWARMS aims to realize enzyme-powered nanobot swarms capable to self-propel using biocompatible and bioavailable fuels and display collective and cooperative behaviours through communication among them as well as with the host environment. The proposal is divided in three working packages. In WP1, I will create a toolbox of nanobots based on a library of enzymes and nanoparticle architectures to study communication and long-range signal propagation using enzyme cascades. WP2 will be devoted to the collective behavior of nanobot swarms, exploiting biomimetic strategies such as chemotaxis and stigmergy to guide and recruit other nanobots. WP3 aims at studying, as a proof-of-concept of the applicability of intelligent nanoswarms for biomedical applications, cooperative behavior among nanoswarms for enhanced drug delivery and medical imaging.
Metabolic control of rna-protein and rna-rna interactions in cellular transformation.

In the current paradigm of gene expression, the structure of messenger RNA (mRNA) is a key element of posttranscriptional control because it modulates interactions with RNA-binding proteins (RBPs). RBPs typically recognize RNA-binding domains to form ribonucleoprotein complexes that ‘commit’ mRNAs to specific functions, and mutated or deregulated RBPs are implicated in multiple neurodegenerative diseases and cancer. Yet, the knowledge on the dynamic regulation of ribonucleoprotein complexes in mammalian cells is limited, mostly because the ‘structure’ and ‘specificity’ of RNA-protein interactions are amply unexplored. Recently, the host laboratory developed a new technique – hiCLIP – which identifies the transcriptome-wide RNA secondary structures (RNA duplexes) bound by particular RBPs, paving the way for pioneering research on the ‘structural determinants’ of RNA function in mammalian cells. In this context, N6-methyladenosine (m6A) is the most prevalent internal modification in mRNAs with critical functions in RNA stability, and seminal studies recently showed that m6A ‘marks’ destabilize in vivo RNA duplexes in the mammalian transcriptome. However, i) how m6A ‘marks’ regulate RNA-protein interactions that rely on RNA secondary structures is unknown, and ii) there is no systems-level elucidation of which RBPs are sensitive to m6A. Importantly, the ‘maintenance’ of m6A levels requires metabolic substrates and the m6A protein machinery is implicated in obesity and cancer. Collectively, these evidences point to a structural role of m6A in RNA function, and raise the compelling notion that metabolic control of m6A may represent a ‘regulatory module’ of gene expression in mammalian cells. The research proposed herein is designed to reveal the ‘regulatory principles’ of RNA structures in cell physiology, and the prospective results are likely to provide far-reaching insights on the significance of this process for metabolism-related diseases and cancer.
Kinect-Based Easy 3D Object Reconstruction

AbstractInspired by the recently developed KinectFusion technique, which is able to reconstruct a 3D scene in real time through moving Kinect, we consider improving KinectFusion for 3D reconstruction of a real object. We make some adaptations to KinectFusion so as to identify the object-of-interest and separate the 3D object model from the entire 3D scene. Moreover, considering that the 3D object model generated by KinectFusion often contains some clearly visible outliers due to the noisy Kinect data, we propose a refinement scheme to remove the outliers. Our basic idea is to make use of the existing powerful 2D segmentation tool to refine the silhouette in each color image and then form visual hull via the refined dense silhouettes to improve the 3D object model. Experimental results show improved performance.Keywords3D reconstructionKinect2D segmentationvisual hull
Utility of virtual unipolar electrogram morphologies to detect transverse conduction block and turnaround points of typical atrial flutter

BackgroundNoncontact mapping is useful for the diagnosis of various arrhythmias. Virtual unipolar electrogram morphologies (VUEM) of the conduction block and the turnaround points, however, are not well defined. We compared the VUEM characteristics of a transverse conduction block in the posterior right atrium (RA) with those of contact bipolar electrograms obtained during typical atrial flutter (AFL).MethodsContact bipolar electrograms were used to map the posterior RA during typical AFL in 16 patients. Twenty points of the VUEM recorded along the block line were analyzed and compared with contact bipolar electrograms.ResultsSeventeen AFLs were analyzed. Fifteen AFLs showed an incomplete transverse conduction block in the posterior RA by contact bipolar mapping. A double potential on the block line corresponded to the two components of the VUEM, in which the second component showed an Rs, RS, or rS pattern. At the turnaround point, a fused double potential of the contact bipolar electrograms corresponded to a change of the second component of the VUEM from an rS to a QS morphology. Two AFLs showed a complete block line in the posterior RA. The contact bipolar electrogram showed double potentials from the inferior vena cava to the superior vena cava, whereas the second component of the VUEM remained in an unchanged Rs, RS, or rS pattern.ConclusionVUEM analysis was a reliable method for identifying the posterior block line during AFL. This method may also be applicable for detecting block lines and turnaround points of circuits in other unmappable arrhythmias.
Contested waters: rio de janeiro’s public water supply and the social structuring of the city

The objective of the project is to write a social and political history of colonial and imperial Rio de Janeiro (16th to 19th centuries) along the lines of its expanding water supply. It is based on the assumption that the access to and control of water were closely related to the social and political struggles and structures in the city. Although not particularly scarce in its occurrence, due to the special geological situation, water and the water supply have always been more contested in Rio de Janeiro than in many other cities. Therefore water, with its highly transient availability but continuous relevance for all parts of society, is a topic suited to uncover important aspects of urban history, for specific situations as well as for broader developments, and ultimately for understanding how European rule in the overseas empires was constantly and extensively challenged by local circumstances. Furthermore, the project will give a response to the theoretical question about the relevance and applicability of environmental history to other fields of history, and encourage a more reflected and socially engaged thinking about some of the most pressing problems of our current world: the property, control and management of water – and harmful potential which can emanate from it.