SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Origins of water content variations in the suboceanic upper mantle: Insight from Southwest Indian Ridge abyssal peridotites

To investigate the origin of heterogeneous water distribution in the suboceanic lithospheric mantle, we performed a detailed petrological and geochemical analysis of abyssal peridotites collected from two localities (53°E and 63.5°E) on the Southwest Indian Ridge. These serpentinized peridotites display primary olivine-orthopyroxene-clinopyroxene-spinel assemblage and record equilibrium temperature of 1150–1200°C and around 1000°C for the 53°E and 63.5°E locations, respectively. The rocks were thus equilibrated in the spinel stability field prior to their exhumation to the seafloor. Our FTIR analyses show variable water contents in orthopyroxene ranging from 24 to 262 wt ppm H2O. Orthopyroxene in the 63.5°E peridotites is characterized by homogeneous and high water content (>200 ppm), whereas orthopyroxene in the 53°E peridotites displays a wider range of water contents (24–246 ppm). We first demonstrate that differences in equilibrium conditions (i.e., pressure and temperature) and mineral chemistry and serpentinization cannot explain the water content variations. Melting modeling show that a fractional melting in both garnet and spinel stability fields is needed to explain the MREE and HREE concentrations in clinopyroxene. Enrichment in LREE, high water contents, and high H2O/Ce, however, require a postmelting rehydration event such as metasomatism. Based on petrographic evidence and investigation of chemical heterogeneities at segment/dredge scale, we suggest that this event involves a metasomatic agent enriched in water and incompatible elements. We infer that the small-scale heterogeneities in water and trace elements may result either from successive infiltration of various amounts of melt/fluids as described in the formation of oceanic core complex or from spatial heterogeneities of melt infiltration as observed in peridotite massifs.
MOBILPREF ES UNA EMPRESA FUNDADA EN 1982 PARA LA PRODUCCIÓN DE PANELES SEMIACABADOS PARA LA INDUSTRIA DEL MUEBLE, QUE HA CRECIDO CONSTANTEMENTE A LO LARGO DE LOS AÑOS, GRACIAS A SU CAPACIDAD DE PRODUCCIÓN, TECNOLOGÍA AVANZADA, FLEXIBILIDAD, CALIDAD Y PRECIOS COMPETITIVOS. HASTA LA FECHA MOBILPREF ÃŠ ES UNA REALIDAD DINÁMICA COMPROMETIDA CON LA INVESTIGACIÓN Y EL DESARROLLO CONTINUOS EN EL

*individual* representante C.F. *Código fiscal* TEL. 071-2906911 FAX. CORREO ELECTRÓNICO 071-2906980: *correo electrónico* P.E.C. (PUNTO ELECTRÓNICO certificado) *correo electrónico*
Method of welding titanium alloy parts with titanium insert.

A method of welding opposite end surfaces of two titanium alloy parts (10, 12) kept in alignment by a high energy-density welding process such as electron beam welding, laser beam welding or TIG arc welding, characterized by closely interposing an insert member (14) of either practically pure titanium or Ti-Al binary alloy containing up to 3 Wt% of AI. Owing to thorough alloying of the inserted titanium (14) with the constituents of the fused base metal (10, 12), the weld metal (16) in a weld joint obtained by this method is sufficiently high in both strength and toughness. By an optional postwelding heat treatment, the strength of the weld metal (16) can further be enhanced.
Glassomer – a revolution in glass processing

Glass is a material with unique properties: unmatched optical transparency, heat, pressure, and chemical resistance, outstanding biocompatibility to name but a few. This makes glass the best material for a vast range of key applications, such as optics & photonics for data transfer, smartphone lenses, and Lab-on-a-Chip. However, glass processing techniques are centuries old, and prevent the production of complex structures required in key applications. 
Glassomer GmbH has developed the disruptive Glassomer® Technology, which revolutionizes the use of glass by allowing an almost limitless freedom of design. The unique, patent-pending technology allows structuring of glasses at temperatures below 130 °C, which enables the creation of tiny, complex glass components required in current and future key applications such as in (fiber) optics. The entire production can be done with machines used for polymers (e.g. injection molders), at the same low cost and high production volumes, but with 100% recyclability, 80% less energy consumption and resulting CO2 emissions. This opens up vast current and future markets, as proven by the first orders from companies such as Zeiss, BASF, Heinz Glass, Chanel, AAC for the smartphone market and Molex, a leading global fiber connector vendor. Glassomer has generated major interest with several investors, and has secured two Letters of Intent (LOIs) for impending investments. Glassomer has also won several prestigious awards and secured major interest in world-renown media. 
An award-winning team, world-class advisory board and major companies already as customers are our recipe for successful growth. We have a “100-100-10” Three-Phase Development Plan to grow into a €100 million annual revenue, 100 employee company in 10 years, creating a European center of excellence on “future glass” to ensure Europe’s competitiveness in essential applications.
Hydropower opportunities in the water industry

Water and wastewater treatment processes are energy intensive accounting for around 30 to 80 percent of the industry production cost. Given this background, the water companies agree on the need to identify cost effective and sustainable ways of producing energy to reduce its dependence on fossil fuel for energy generation, reduce its carbon emissions, ensure the security of its power supply and offset the increasingly energy cost. Microhydropower, a resource that is readily available at the door step of the water companies has been identified as the solution to a sustainable energy option for the industry. Nonetheless, there are no detailed options in the available literature of hydropower application to the water industry. This paper thus gives an overview of hydropower application options available to the water industry (water and wastewater treatment industry.
Migration in cities of the global south: drivers, interactions and socio-demographic consequences

Large scale rural-to-urban migration and associated urbanization in developing countries constitute an opportunity but also a risk for human development. In either case, urbanization may lead to increased international migration. Our understanding of the interactions between these two phenomena is constrained by the lack of evidence on subnational heterogeneity in international migration, and the traditional divide between internal and international flows in research. MIC provides the most comprehensive analysis of trends in both types of migration in more than 3000 cities and rural areas spanning all developing regions.  

We address three substantive research questions. In project A, we explore how internal and international migrations evolve over time across educational strata of population, the hierarchical distribution of settlements, and the national settings of urbanization. In project B, we examine why migration trends differ across these contexts. In project C, we investigate how migration transforms cities’ socio-demographic potential for human development. 

MIC is innovative in its global and comparative perspective on migration among metropolitan populations. This is enabled by the integration of spatial data and harmonized census records, creative use of indirect demographic estimation techniques, and advanced statistical methods for data analysis. Each of the three sub-projects has the potential for innovative results that are highly policy-relevant. Projects A & B will provide information on where and why we should expect increased international migration in rapidly urbanizing developing countries, and how this relates to the domestic movements. Project C identifies the consequences of migration for the processes of urbanization and human development. MIC will help governments to tailor their existing migration and development policies, to maximize the development impact of migration, and to make cities more sustainable.
Activation of the SNF2 Family ATPase ALC1 by Poly(ADP-ribose) in a Stable ALC1·PARP1·Nucleosome Intermediate

The human ALC1/CHD1L oncogene encodes an SNF2 family ATPase with a macrodomain that binds poly(ADP-ribose) (PAR). We and others previously showed that ALC1 possesses a cryptic ATP-dependent nucleosome remodeling activity that is potently activated in the presence of PARP1 and NAD(+), its substrate for PAR synthesis. In this work, we dissected the mechanism by which PARP1 and NAD(+) activate ALC1 nucleosome remodeling. We demonstrate that ALC1 activation depends on the formation of a stable ALC1·PARylated PARP1·nucleosome intermediate. In addition, by exploiting a novel PAR footprinting assay, we obtained evidence that the ALC1 macrodomain remains stably associated with PAR on autoPARylated PARP1 during the course of nucleosome remodeling reactions. Taken together, our findings are consistent with the model that PAR present on PARylated PARP1 acts as an allosteric effector of ALC1 nucleosome remodeling activity.
Supporting the scale and growth of digital social innovation in europe through coordination of europe’s dsi and caps networks

The DSISCALE project aims to support policy makers, funders and, most importantly, practitioners to scale digital social innovation (DSI) and collective awareness platforms (CAPs) in Europe and to make the most of the opportunities in using tools such as open data open hardware  to address some of Europe’s biggest social challenges. Building on existing support initiatives such as www.digitalsocial.eu, it will do this by developing Europe wide innovation clusters focusing on collaboration and peer learning between funders, policy makers and practitioners on methods for scaling DSI, developing the DSI index for measuring the macro level system conditions for DSI and a series of ‘DSI futures’ which will explore future scenarios for DSI in Europe and map the emerging digital technologies that are enabling new forms of digital social innovation.  Specifically DSISCALE will:
• Create and facilitate an online community hub for DSI in Europe by continuing the work of www.digitalsocial.eu;
• Develop an index for measuring capacity for DSI;
• Facilitate European DSI clusters that enable practitioners, policy makers and DSI to collaborate and share learning;
• Map current and emerging trends in DSI;
• Set Learning and Policy recommendations.
 These key DSISCALE objectives will be achieved by bringing together resources and knowledge across different fields, technologies and disciplines, including ICT and social sciences, digital democracy the maker movement and innovation policy from across the national and european networks of Nesta, betterplace lab, Waag Society, WeMake, Barcelona Activa, ePaństwo and Fab Lab Barcelona| IAAC and that of the European Commission.
Replacements of Rare Herbs and Simplifications of Traditional Chinese Medicine Formulae Based on Attribute Similarities and Pathway Enrichment Analysis

A Traditional Chinese Medicine (TCM) formula is a collection of several herbs. TCM formulae have been used to treat various diseases for several thousand years. However, wide usage of TCM formulae has results in rapid decline of some rare herbs. So it is urgent to find common available replacements for those rare herbs with the similar effects. In addition, a formula can be simplified by reducing herbs with unchanged effects. Based on this consideration, we propose a method, called “formula pair,” to replace the rare herbs and simplify TCM formulae. We show its reasonableness from a perspective of pathway enrichment analysis. Both the replacements of rare herbs and simplifications of formulae provide new approaches for a new formula discovery. We demonstrate our approach by replacing a rare herb “ Forsythia suspensa ” in the formula “the seventh of Sang Ju Yin plus/minus herbs (SSJY)” with a common herb “Thunberg Fritillary Bulb” and simplifying two formulae, “the fifth of Du Huo Ji Sheng Tang plus/minus herbs (FDHJST)” and “Fang Feng Tang” (FFT) to a new formula “Fang Feng Du Huo Tang” (FFDHT).
Support for small businesses with a turnover exceeding BGN 500 000 to address the economic consequences of the COVID-19 pandemic

Support for small businesses with a turnover exceeding BGN 500 000 to address the economic consequences of the COVID-19 pandemic
TUNING SURFACE PROPERTIES OF MELT BLOWN POLYESTER FIBERS BY HYDROLYSIS AND SOLUTION GRAFTING

Described herein is a continuous process fear modifying the properties of polyester and polyester based fibers, such as a poly(butylene terephthalate) (PBT) fiber, comprising subjecting the PBT fiber to alkaline hydrolysis, and optionally further comprising functionalizing the PBT fiber by solution grafting such as fluorination. The alkaline hydrolysis and optionally subsequent functionalization such as fluorination process can be continuous, following the melt blowing/spinning or spun-bonding process. Also described is a nonwoven PBT fiber mat obtained by the surface modification process. Further described is a filtration device comprising the nonwoven PBT fiber mat.
Typical agri-food production in the province of Venice: support, information, organization and enhancement actions - Cross-border initiatives with the Slovenian territory. 

This initiative follows two intervention lines. The first one concerns the planning of the support to be provided to farms and agri-food companies in the Venetian territory and in the Slovenian part of the Gorizia area, in order to widen their knowledge about production, promotion and marketing techniques of typical products and to foster commercial partnerships. The second one envisages promotion and information interventions. During the first workshop, which was undertaken in April 2005, the certification and marketing of typical and quality products in the Venetian and Slovenian areas were debated, involving some teachers of Nova Gorica Agricultural School. Later on, other specialized workshops were held to deal with the agri-food sectors (fruit and vegetables, vine-growing and wine-making, dairy, fish and aquiculture); they took place both in classrooms and in the headquarters of the most representative firms and institutions in the province of Venice. In the framework of this project, ten multilingual informative brochures have been published; each of them concerns a typical product, such as the DOC (registered designation of origin) wines produced in the Piave and Lison Pramaggiore areas, ITG (typical geographic indication) wines produced in the Estern Veneto region and finally some food products such as montasio cheese, radicchio variegato and radicchio rosso from Chioggia. Overall, through the informative meetings, this initiative has provided a broad overview of the agri-food production system in the Veneto region, thus fostering a constructive debate and exchange of opinions about the Venetian and Slovenian territories.
Ghanaian Junior High Science Teachers’ Reflections on the Use of Tessa Secondary Science Modules

The study investigated in-service Junior High School science teachers’ reflections on the use of TESSA secondary science modules. The sample consisted of 34(8 females and 26 males) Junior High School science teachers in Winneba in Central Region of Ghana. Descriptive survey with mixed methods approach was used to collect data using questionnaire and focus group discussion as data collection instruments. The quantitative data collected were analysed through frequency counts and simple percentages while thematic approach was used to analyse the qualitative data. Among other findings, majority of the participants reported that the use of the TESSA resources provided innovative ways of presenting science lessons to their pupils. Also, the participants indicated that their pupils enjoyed and fully participated in these lessons. These notwithstanding, 94 % (32) of participants reported among other things that, accessibility of hard copies of resources would be a challenge to them since most schools did not have ICT tools from which they could print out materials. It is therefore recommended that copies of TESSA secondary science modules be made available in all schools for effective implementation by teachers.
FUEL CONTROL SYSTEM AND METHOD FOR GAS ENGINES

A gaseous carburetor or fuel control system includes a fuel metering assembly, a venturi mixer assembly, a throttle assembly, and an electronic control unit. The control unit controls the fuel metering assembly in a closed loop manner based on detected gas and air pressure to an air/fuel mixing venturi. An electronic governor which controls the throttle valve may also be controlled by the same control unit which controls the fuel metering assembly, using a separate control loop.
Diabetic nephropathy modelling in hesc-derived 3d kidney organoids

Diabetic Nephropathy is the leading cause of end-stage renal disease (ESRD). To date, treatment of DN is mainly based on drugs acting on glycaemic and blood pressure control, as there is no validated therapy able to stop the progression towards renal failure. One of the main impediments for developing new therapies for DN has been the lack of a good preclinical model which can recapitulate important functional, structural, and molecular features of advanced human diabetic kidney disease. Here, we aim to develop a DN modelling using human Embryonic Stem Cell (hESC) derived kidney organoids which can recapitulate the in vivo architecture, functionality, and genetic signature of DN. Due to the increasing evidences that links aberrant DNA methylation with kidney fibrosis and metabolic reprograming in DN, we hypothesize that early DN progression is promoted by the metabolic alterations occurring in diabetic patients, resulting in the epigenetic reprogramming of kidney proximal tubular epithelial cells (KPTCs). Based in my background in the fields of metabolism and diabetes, together with the expertise of Dr. Montserrat in the field of somatic reprograming, DN and tissue regeneration/differentiation, this proposal seeks to:1) Elucidate the methylation status of the promoters/enhancers of genes encoding enzymes and regulators of fibrosis and fatty acid oxidation in proximal tubular cells obtained from diabetic patients at different stages of DN progression 2) Establish two in vitro models using hESC-derived kidney organoids; an engineered DN in vitro model, using CRISPR Cas9 to mimic the epigenome signature of DN patients and a physiological DN in vitro model which mimic the diabetic physiological chemistry. The information gained from this DN modelling will offer improved insight into disease pathology and progression. Moreover, it may also serve as a tool for drug discovery to identify therapeutic targets for DN.
A bZIP Protein, VIP1, Is a Regulator of Osmosensory Signaling in Arabidopsis 

Abscisic acid is a stress-related phytohormone that has roles in dehydration and rehydration. In Arabidopsis (Arabidopsis thaliana), two genes that inactivate abscisic acid, CYP707A1 and CYP707A3, are rapidly up-regulated upon rehydration. The factors that regulate CYP707A1/3 are not well characterized. We expressed a bZIP protein, VIP1, as a green fluorescent protein fusion protein in Arabidopsis and found that the nuclear localization of VIP1 was enhanced within 10 min after rehydration. A yeast one-hybrid assay revealed that the amino-terminal region of VIP1 has transcriptional activation potential. In a transient reporter assay using Arabidopsis protoplasts, VIP1 enhanced the promoter activities of CYP707A1/3. In gel shift and chromatin immunoprecipitation analyses, VIP1 directly bound to DNA fragments of the CYP707A1/3 promoters. Transgenic plants expressing VIP1-green fluorescent protein were found to overexpress CYP707A1/3 mRNAs. The time course of nuclear-cytoplasmic shuttling of VIP1 was consistent with the time courses of the expression of CYP707A1/3. These results suggest that VIP1 functions as a regulator of osmosensory signaling in Arabidopsis.
Participatory engagement with scientific and technological research through performance

The PERFORM consortium aims to investigate the effects of the use of innovative science education methods based on performing arts in fostering young peoples’ motivations and engagement with science, technology, engineering, and mathematics (STEM) in selected secondary schools in France, Spain and the United Kingdom. A considerable percentage of young people in Europe is not interested in STEM careers mainly because they perceive that they lack the skills to deal with such topics. Such negative perceptions discourage adolescents from investing time in learning about science and undervalue the role of science in society. Addressing the challenge of engaging young people in STEM has never been more urgent in Europe in order to avoid loss of scientific talent and to ensure future innovation capability, excellence and competitiveness. PERFORM takes action to overcome the remaining distance between young people and science and to break the unidirectional model of scientific knowledge transfer. PERFORM will explore a creative, participatory educational process on STEM through the use of scenic arts with secondary school students, their teachers and early career researchers, who will get actively involved in experiencing science. They will also reflect on their own role in the interaction between science and society, and the values embedded in Responsible Research and Innovation. PERFORM will analyse how such human-centred, science-arts educational approach contributes to foster girls’ and boys’ motivations towards science learning and strengthen the transversal competences they will need for STEM careers and jobs. The education and communication skills required for teachers and researchers to further replicate the educational process will be explored and addressed in specific training toolkits. The project dissemination will be fulfilled by ensuring strong science-policy links and by linking PERFORM with Scientix.
Straddle-type vehicle

The present invention relates to a straddle-type vehicle comprising a footrest (17a), on which a driver can put at least a portion of a sole, and an operating pedal (19) vertically swingable about a rotating shaft (18) extending in width direction of the straddle-type vehicle, the operating pedal (19) comprising at least one pedal body (19b,19c) connected to the rotating shaft (18) and at least one operating portion (20,21) on which the driver can apply a treading operation when putting the sole on the footrest (17a), the operating portion (20,21) being arranged substantially at a swingable end of the pedal body (19b,19c), wherein the operating portion (20,21) includes a substantially upwardly projecting tread surface (20a,21a).
Pebble distribution unit for road work, has device for channeling layer of pebbles in outlet of roller, where device is produced by partition units situated in extension of partition and extended above axis of roller

The unit has a diffuser with partitions (3) orthogonally interlocked with a sheet (2) for defining a passage (E) for flow and distribution of pebbles (G). A device intended for channeling layer of the pebbles in an outlet of a roller (1) is produced by partition units (3B) situated in an extension of the partition and extended above an axis (X) of the roller up to a zone of the layer in the outlet of the roller.