SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Translating evidence into policy for cardiovascular disease control in India

Cardiovascular diseases (CVD) are leading causes of premature mortality in India. Evidence from developed countries shows that mortality from these can be substantially prevented using population-wide and individual-based strategies. Policy initiatives for control of CVD in India have been suggested but evidence of efficacy has emerged only recently. These initiatives can have immediate impact in reducing morbidity and mortality. Of the prevention strategies, primordial involve improvement in socioeconomic status and literacy, adequate healthcare financing and public health insurance, effective national CVD control programme, smoking control policies, legislative control of saturated fats, trans fats, salt and alcohol, and development of facilities for increasing physical activity through better urban planning and school-based and worksite interventions. Primary prevention entails change in medical educational curriculum and improved healthcare delivery for control of CVD risk factors-smoking, hypertension, dyslipidemia and diabetes. Secondary prevention involves creation of facilities and human resources for optimum acute CVD care and secondary prevention. There is need to integrate various policy makers, develop effective policies and modify healthcare systems for effective delivery of CVD preventive care.
Multiscale thermal-related urban climate analysis and simulation tool

Climate change and global warming are widely recognized as primary challenges in the next years. Indeed, despite several international agreements, CO2 and global heating continue growing and, in urban areas, increase of temperatures and frequency of heat waves, threaten health and well-being of citizens. Here, the loss of natural areas, morphological and thermal properties of materials, critically affect urban climate, causing city to be warmer than surrounding areas. This phenomenon, known as Urban Heat Island (UHI), needs to be carefully addressed. To address public health and well-being, soft mobility and public transport are increasingly promoted by Cities. Also, the current sanitary contingency has further urged such policies. But, longer and hotter summers are a deterrent for citizens to living outdoors. MultiCAST will implement a thermal comfort-related urban Decision Support System (DSS) to inform pedestrian oriented climate planning and design. The DSS will rely on a user-friendly Web-GIS as mainstreaming tool to respond the UHI into urban programs, policies and instruments. A novel approach to incorporate geo-referenced outdoor climate and walkability into pedestrian flows modelling will be developed. It will rely on replicable methods for automatic acquiring and mapping precise and updated thermal-related urban climate data, estimate walkability based on Google Street View urban-scapes, then introducing climate and walkability into street network analysis. MultiCAST will support modelling walking routes to interest points such as commuter-rail and -metro stations, or ‘hot’ and ‘cool’ islands. A simulation function will allow estimate scenarios, compare and visualize the effects of different urban climates. Three urban areas will be tested in Los Angeles, Amsterdam, and Milan. Open climate datasets will be available through the Web-GIS. Besides, a framework of GIS data, procedures, scripts, and manuals will be provided to allow replicate the methodology.
<i>Magnolia officinalis</i>Extract Contains Potent Inhibitors against PTP1B and Attenuates Hyperglycemia in db/db Mice

Protein tyrosine phosphatase 1B (PTP1B) is an established therapeutic target for type 2 diabetes mellitus (T2DM) and obesity. The aim of this study was to investigate the inhibitory activity of Magnolia officinalis extract (ME) on PTP1B and its anti-T2DM effects. Inhibition assays and inhibition kinetics of ME were performed in vitro . 3T3-L1 adipocytes and C2C12 myotubes were stimulated with ME to explore its bioavailability in cell level. The in vivo studies were performed on db/db mice to probe its anti-T2DM effects. In the present study, ME inhibited PTP1B in a reversible competitive manner and displayed good selectivity against PTPs in vitro . Furthermore, ME enhanced tyrosine phosphorylation levels of cellular proteins, especially the insulin-induced tyrosine phosphorylations of insulin receptor β -subunit (IR β ) and ERK1/2 in a dose-dependent manner in stimulated 3T3-L1 adipocytes and C2C12 myotubes. Meanwhile, ME enhanced insulin-stimulated GLUT4 translocation. More importantly, there was a significant decrease in fasting plasma glucose level of db/db diabetic mice treated orally with 0.5 g/kg ME for 4 weeks. These findings indicated that improvement of insulin sensitivity and hypoglycemic effects of ME may be attributed to the inhibition of PTP1B. Thereby, we pioneered the inhibitory potential of ME targeted on PTP1B as anti-T2DM drug discovery.
Micrornas as therapeutic targets for arvc.

ARVC is a hereditary disease mainly characterised by the progressive substitution of the myocardium with fatty or fibro-fatty tissue involving predominantly the right ventricle. Clinically, ARVC shows wide variation between individuals. Together with modifier genes, common sequence variants, and environmental as well as endogenous factors, epigenetic modifiers such as miRNAs are hypothesized to be potential targets for disadvantageous environmental stimuli and may lead to the onset of complex and heterogeneous diseases such as ARVC. The main research objective of this EF is to assess and validate the relevance of disease mechanisms underlying the development of ARVC and to identify novel RNA-based targets in mouse models and ARVC patients. The EF programme comprises two tightly linked components – research and complementary training - that will be complemented with secondments in two (non-) academic organisations active in the field of molecular cardiology. The host organisations are strongly committed to enhancing the creative and innovative potential of the ER who wishes to diversify her individual competence in terms of skill acquisition to become a successful European scientist.
Nanotechnology for Market

NANO4M aims at improving strategies and building networks to design nanotechnology for market. The project tackles some of the challenges identified in relation to the functioning of the regional innovation systems with the following objectives: 
• To improve the regions’ capacity to shorten the gap between R&D and market testing new Research-to-Market processes (R2M) 
• To strengthen the interregional collaboration by identifying and developing specific research and business opportunities of common interest in the emerging field of nano/microtechnology
• To increase competitiveness of innovation infrastructure at regional, national and European level 
• To improve the efficiency of regional innovation policies by drawing recommendations and implementing best practices
NANO4M involves four regions and eleven partners. Northrhine-Westfalia and Lorraine are at the cutting edge of nanotechnology development and they host some of the most importan European related clusters. In Asturias and Tuscany promising research facilities are currently under construction. The different profiles of the regional R+D+I strategies of these four regions as well as their common interest on several markets/technologies are the best basis for the project to reach its objectives. Each region is represented by a Regional or Local Authority and one or two Research and Technological Centers. Besides, NANO4M will offer an adequate forum for an innovative approach: the integration and implementation of new knowledge and skills through the creation of interdisciplinary expert groups.
Some activities will be focused on the exchange of experiences: seminars, conferences, study visits, reports ,maps and a good practice guideline. These activities will create a platform for the constitution of expert teams. The implementation of the new knowledge obtained through this interdisciplinary collaboration will be used for the development of feasibility studies concerning the market opportunities of new products in the nano/micro areas and identifying success and failure factors for Research to Market process in each region. Furthermore, the expertise obtained in the expert groups will also be embedded in the elaboration of strategic plans for the participating research and technology centers. NANO4M will contribute to the INTERREG IVC goal of improving the efficiency of regional policies by drawing recommendations for Regional Innovation Policies.
Research labs in the alpine area

RE-SEARCH ALPS project consists in a tool to support the systemic goal to enhance innovation ecosystems is to know and map Laboratories and Research Centers in the Alpine Macroregion. This knowledge is extremely valuable, since scientific and technical laboratories, research centers, innovation centers (both public and private) are pillars of the endowment for the supply of scientific and technical knowledge to the society. They constitute an asset to support economic and social development. Data on those infrastructure are valuable to develop tools for users (enterprises, public administrations, universities, service centers, among others) that are complementary in industrial policy measures supporting SMEs in using knowledge-intensive services and research activities provided by labs in the area. At present there is no systematic information to address those issues in the EUSALP countries.
EUSALP support to the RE-SEARCH ALPS project will also provide a robust testbed for its extension to other EU countries. Relevant interactions with Elsevier will provide support for further integration of relevant data.

The project will allow to support the research and development process to know:
- what the laboratories and research centers do,
- where they are located,
- where excellence emerges, according to research fields / themes and numbers (active researchers, published papers, won prizes, running EU projects, gotten patents, etc),
- people working in a specific center and determining its excellence,
- network of relations they highlight in their websites.

The project is strongly based on the CEF Building Blocks for data translation and user identification.
In collaboration with the consortium, a number of Public Administrations, acting as data providers and application users, is included in the consortium, thus guaranteeing the maximum coverage of the dataset and a high quality and usability of the data and tool.
OVEN ENCLOSURE AND VENTILATION SYSTEM

A conveyor oven (Fig. 2) system is disclosed which includes a hood means (20) which extends over the conveyor oven (Fig. 1) and supplies make-up air and exhausts heated air. The enclosure system includes front enclosure (40) and rear enclosure walls (41) which are parallel to and spaced apart from the front and rear oven walls of the oven respectively. Additionally, a first enclosure end wall (not shown) is also included which is parallel to and spaced apart from the first oven end wall. A second enclosure end wall (45) which is parallel to and spaced apart from the second oven end wall is also included. In the enclosure system of the present invention there is an entry opening (50) in at least one of the enclosure walls which is adapted to correspond to each entry opening in the oven's walls. An exit opening (52) in at least one of the enclosure walls is provided which is adapted to correspond to each exit opeing in the oven's walls. The hood means enclosure (24), front enclosure (40), rear enclosure (41), first enclosure end, and second enclosure end walls (45) of the present invention are configured such that make-up air passes over the front oven, rear oven, first oven end, and second oven end walls before being exhausted through the hood means.
Enabling the transferability of cycling innovations and assessment of its implications

HANDSHAKE supports the effective take up of the integrated cycling solutions successfully developed by Amsterdam, Copenhagen and Munich, our Cycling Capitals and world-renowned cycling front runners, to our 10 highly committed Future Cycling Capitals, Bordeaux Metropole, Bruges, Cadiz, Dublin, Helsinki, Krakow, Greater Manchester, Riga, Rome and Turin. Our partner cities are combined in a composite working environment in which diverse geographical contexts, socio-economic conditions and planning cultures work toward the same goals, that is, delivering the desired cycling change. The project believes that effective transfer can happen only in the presence of: i) state-of-art body of knowledge on cycling policy and solutions; ii) sustaining transition processes; iii) motivating and supporting forms of mentorship. In HANDSHAKE this is ensured by the presence of 3 cycling planning champions, the employment of highly innovative methods brought together into a supportive and novel transfer cycle (including Bikenomics, Immersive Study Tours and Transition Management), and a mentorship programme that takes by the hand each participating city. The gathered team will cooperate to reach a number of strategic objectives: i) Inspire the creation or refinement of holistic cycling visions and concrete transfer approaches; ii) Foster the adoption of a multidisciplinary planning culture to empower the project process and consolidate future cycling policies and investments; iii) allow cycling to become a key element of urban transport; iv) Improve cycling modal share and safety; v) Leverage the potential of cycling as a critical congestion relief tool; vi) Leverage cycling to improve public health; vii) Foster economic growth. HANDSHAKE expects to improve cycling attractiveness by +52% and competitiveness by 17%, shift ca. 60.000 people to cycling with +34% in frequency of cycling use, 37,5% in accidents, traffic levels lowered by 6,34%, and CO2 savings of -3.706.000 kg CO2/year.
Massively parallel lossless compression of medical images using least-squares prediction and arithmetic coding

Medical imaging in hospitals requires fast and efficient image compression to support the clinical work flow and to save costs. Least-squares autoregressive pixel prediction methods combined with arithmetic coding constitutes the state of the art in lossless image compression. However, a high computational complexity of both prevents the application of respective CPU implementations in practice. We present a massively parallel compression system for medical volume images which runs on graphics cards. Image blocks are processed independently by separate processing threads. After pixel prediction with specialized border treatment, prediction errors are entropy coded with an adaptive binary arithmetic coder. Both steps are designed to match particular demands of the parallel hardware architecture. Comparisons with current image and video coders show efficiency gains of 3.3-13.6% while compression times can be reduced to a few seconds.
Brilliant researchers impact on growth health and trust in research.

The BRIGHT project aims at enhancing the visibility and perception of researchers among the general population in the Tuscany Region, simultaneously with all the European  Researchers’ Night (ERN) initiatives.
BRIGHT acronym means “Brilliant Researchers Impact on Growth Health and Trust in research”, wishing to underline the positive aspect of the research activity in order to convey a positive message to the general public.
BRIGHT is planned in for two years - i.e. two events, one in 2016 and another in 2017 - and livens up not only two “nights” with entertaining and exciting events spread across the main Tuscany cities,  but it also creates a lot of initiatives aiming at building permanent “Research Urban Trekking” paths leading towards the complete awareness of the researcher’s role in society. “Researchers make your life better!” is the guiding principle stemming from the passion, the enthusiasm and hard intellectual work of researchers’ daily work and how this contributes to the well-being of the general population. BRIGHT focuses on creating awareness on the important role played by researchers in addressing the great challenges ahead, such as health and wellbeing, new technologies, sustainable development, physical and biological challenges, cultural heritage.
BRIGHT will be successful if it will be able to convince the population of the IMPACT of the researchers and the research's products for the development of the society, and to make people TRUST the researchers instead of being driven away by hoaxes with no scientific basis.
Tumour Budding and Survival in Stage II Colorectal Cancer: a Systematic Review and Pooled Analysis

Tumour budding is defined as the presence of isolated or small clusters of malignant cells at the invasive edge of the tumour. It is considered a negative prognostic factor in colorectal cancer (CRC) and is associated with a poor outcome and adverse pathological features. Here, we report a meta-analysis of the association of tumour budding and survival in stage II CRC patients.PubMed, EMBASE, Web of Science and SCOPUS were searched for studies that assessed the relationship between tumour budding and 5-year overall survival (OS) in stage II CRC patients. Published data were extracted and used to compute odds ratios (ORs) for death at 5 years and hazard ratios (HRs) for survival amongst patients with respect to the extent of tumour budding, using multivariate analysis. Data were pooled using the Mantel-Haenszel random effect model.We analysed 12 studies that included a total of 1652 patients. High-grade budding was associated with worse OS at 5 years (OR for death, 6.25; 95 % confidence interval [CI], 4.04-9.67; P < 0.00001). The absolute difference in 5-year OS was -25 % (95 % CI, -18- - 33 %, P < 0.00001). It was particularly noteworthy that the presence of high-grade budding was associated with an increased risk of death (HR for death, 3.68; 95 % CI, 2.16-6.28, P < 0.00001).Tumour budding is associated with worse survival in stage II CRC, in particular in pT3N0M0 patients. It could therefore potentially be used when deciding whether to administer adjuvant chemotherapy in high-risk node negative CRC patients.
TARGETED GENE TRANSFER USING G PROTEIN COUPLED RECEPTORS

A method of delivering heterologous nucleic acid (e.g., a gene sequence) into a cell comprises attaching a virus containing a heterologous gene sequence to a G protein coupled receptor (i.e., a seven transmembrane receptor such as the P2Y2 receptor). The virus may be attached to the receptor by means of a bridging antibody, or by binding an antibody specific for the receptor with an antibody specific for the virus, wherein the antibody that specifically binds with the receptor and the antibody that specifically binds to the virus are cross-linked. Alternatively, the virus may express a peptide that specifically binds to the receptor. The receptor may be induced to internalize by means of the addition of a ligand known to trigger internalization of the receptor into the cell.
Enhanced in situ bioremediation for contaminated land remediation

EiCLaR, as a EU/China consortium, will develop scientific and technical innovations for in situ bioremediation technologies that will be directly developed into industrial processes for the rapid efficient cost-effective treatment of a range of environmental pollutants such as chlorinated solvents, heavy metals, pesticides, etc. These technologies (Electro-nanobioremediation, innovative Bioaugmentation, Bioelectrochemical remediation, Enhanced phytoremediation) will enable bioremediation approaches to expand their range of applications to industrial sites and waters that contain complex, high concentration pollutant mixtures. This project will move our proof-of-concept level advances to industrial commercial processes through laboratories studies to refine the processes and to explore the scientific base and scale-up techniques and field demonstrations.  Our recent advances in nanobioremediation will be enhanced by studies of the critical microbial component and the use of electrochemical processes to increase the degradation rate and biocatalyst lifetime. The innovative bioaugmentation is based on a recently discovered bacteria capable of degrading some chlorinated solvents efficiently under aerobic conditions.  The Bioelectrochemical system will speed up the anaerobic degradation of pollutants when aeration is not feasible.  The enhanced phytoremediation will benefit from the synergistic effect of fungi and electrokinetic nutrient dispersion. These environmental sustainable and low impact depollution methods will provide service companies with the tools to manage contaminated soil and water and improve environmental quality at over a million sites throughout Europe and China. These companies will be able to grow by increased personnel and revenue while improving biodiversity and reducing environmental risks.
Marketing IV pour DESTILA

Le projet est mis en œuvre dans le but d’atteindre et d’attirer de nouveaux clients par la participation à des foires commerciales internationales, renforçant ainsi notre compétitivité sur le marché international et augmentant les ventes de l’entreprise. Il est prévu de participer à 10 salons internationaux sélectionnés pour atteindre des clients potentiels d’Europe de l’Ouest et d’Europe de l’Est, avec un chevauchement avec le reste du monde.
FUEL FLOW METER DEVICE FOR A FUEL DISPENSER, SYSTEM AND METHOD

A flow switch used on conjunction with a fuel flow meter in a fuel dispenser to determine when fuel flow rate signals from a fuel flow meter should be ignored in the calculation of flow rate and/or volume of fuel dispensed. An inferential fuel flow meter may be used as the fuel flow meter. The inferential fuel flow meter may be a turbine flow meter that comprises one or more turbine rotors that rotate in response to fuel flow flowing through the turbine flow meter. The turbine rotors may continue to generate pulses even when fuel is no longer flowing. A flow switch determines when fuel is actually flowing and fuel is not actually flowing. The flow switch is described as either a single poppet or dual poppet flow switch in examples described herein.
CONTROL DEVICE OF GAS-DISCHARGE LIGHT SOURCE

The invention relates to electrical engineering. The essence of the invention: a control device of gas-discharge light source having a resonant circuit with forked connections of a choke and capacitor, starting switch, an ignition pulse former, power-supply mains, control-and command circuit with a microprocessor control unit having line-operated telemetric receiver and transmitter interacting with unit of timing and detector of frequency-modulated signals, elements of load state control, elements of current and voltage monitoring.