SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Securing a healthy indoor air climate while saving energy in buildings with space technology

90% exposure to air pollution does occur indoors, causing almost 70% of the total burden of disease related to indoor air quality. With 90% of European citizens spending 90% time indoors, good environment inside buildings is a key public health issue, costing €1,273 B each year. 
Overall, air treatment is responsible for 40% of total building energy consumption, and ventilation-related operations represent alone up to 26% of the electricity expenses. This is because current ventilation approaches consume huge amounts of energy by replacing indoor air with air from polluted outdoor environment. Thus, they need to choose between air quality and energy savings, so the better indoor air quality they achieve, the more energy spending, and the opposite way around. 
SALLY_R is a Swedish cleantech SME that has been awarded twice already for its disrupting innovation, s8AIR, an Air Handling Optimization System that guarantees optimum indoor air quality spending 40% less energy. For an average office building area of 870m, S8AIR‘s energy savings (0.3 kWh/m2/day) would lead to less 63.5 MWh/year energy consumed, amounting for €12,970/year. 
s8AIR combines ventilation approaches used on Earth with the actual technology for climate control in the International Space Station to enhance the performance of air handing units no matter capacity. This is achieved thanks to our own developed smart algorithm that intelligently exploits the real-time data acquired from several sensors. 
Our novel system can be integrated either into existing Air Handing Units in building refurbishment/renovation operations or into new units, so after having demonstrated our product capabilities through the easy deployment in refurbished buildings, we will target AHU manufacturers to integrate S8AIR into their well-known products. With this strategy, we aim to generate €30.2 million accumulated revenues (€10.7 million profit) by 2023, with the creation of 17 direct jobs.
Ontology-Based knowledge access for the higher education and research sector

The aim of the project is to design a system to support the knowledge base of SIRIS Academic S.L., a consultancy company specialized in higher education and research. 
With a PhD in Knowledge Representation and reasoning, and a knowledge of related state-of-the art tools, the Associate will be invited to apply the so-called Semantic Web and Ontology-based Data Access (OBDA) technologies for the integration of the HE&R knowledge corpus currently used by our consultants.
This knowledge base should facilitate the organisation of the consultants' qualitative knowledge of the sector. It will be a tool to train future consultants, and - in connection with the open data query portal already developed by SIRIS - an instrument to enhance the quality of the consultancy. The Innovation Associate will work on the direct supervision of a senior consultant of the company, as well as a research specialised in KR and ontology. He/she is expected to a) get an in-depth knowledge of the current state of SIRIS's knowledge and tool to generate ideas of KM tools; b) implement a first prototype and get users' feedback; c) set up a plan to scale up the prototype at the level of the company.
Dissecting the mechanism of the regulation of γturc-mediated microtubule nucleation

Cells regulate the nucleation of microtubule polymerization locally and temporally, which is translated into accurate organization of the microtubule cytoskeleton, crucial for proper cell function. It is well established that the major microtubule nucleator in animal cells, the γ-tubulin ring complex (γTuRC), is central for such regulation and its implication in disease is clear. However, for more than 20 years, nobody was able to dissect the molecular mechanism of microtubule nucleation by γTuRC, a current big question in the microtubule area of research. Now, this project will make this challenge achievable by taking advantage of very recent technological advancements in the microtubule field. Aiming to dissect the molecular mechanism of γTuRC-mediated nucleation, the work here proposed will pioneer the reconstitution of physiological microtubule nucleation by γTuRC, using an original combination of biochemistry, single molecule microscopy and structural biology approaches. This will contribute to the progress in understanding microtubule organization and dynamics in cells, and will open new perspectives to explore further the molecular mechanisms behind the diseases associated to γTuRC and γTuRC-associated proteins (e.g. neurological conditions and cancer). This proposal will not just accomplish the current challenges in the cytoskeletal field as will serve as the basis to understand and possibly treat such diseases, which are included on the European Union research priorities regarding the Horizon 2020 program. The creative and innovative nature of this project will also place myself, the host lab and the Institute where the project will be developed, and the EU in the forefront of research in the microtubule cytoskeletal field, contributing to my main goal in becoming a leader in molecular and cell biology of the cytoskeleton, in Europe.
FOURIER ANALYSIS OF BLAZAR VARIABILITY: KLEIN–NISHINA EFFECTS AND THE JET SCATTERING ENVIRONMENT

The strong variability of blazars can be characterized by power spectral densities (PSDs) and Fourier frequency-dependent time lags. In previous work, we created a new theoretical formalism for describing the PSDs and time lags produced via a combination of stochastic particle injection and emission via the synchrotron, synchrotron self-Compton, and external Compton (EC) processes. This formalism used the Thomson cross section and simple $\delta$-function approximations to model the synchrotron and Compton emissivities. Here we expand upon this work, using the full Compton cross section and detailed and accurate emissivities. Our results indicate good agreement between the PSDs computed using the $\delta$-function approximations and those computed using the accurate expressions, provided the observed photons are produced primarily by electrons with energies exceeding the lower limit of the injected particle population. Breaks are found in the PSDs at frequencies corresponding to the cooling timescales of the electrons primarily responsible for the observed emission, and the associated time lags are related to the difference in electron cooling timescales between the two energy channels, as expected. If the electron cooling timescales can be determined from the observed time lags and/or the observed EC PSDs, then one could in principle use the method developed here to determine the energy of the external seed photon source for EC, which is an important unsolved problem in blazar physics.
Precisely patterned nanofibers for high performance bioseparations

Biopharmaceutical drugs save lives and drastically improve well-being. The number of new bio-drugs approved or in pipeline is rising but only 1/4 of patients have access to them. Bioseparation is a critical step in biopharmaceuticals manufacture. Bioseparation processes have low productivity, and are responsible for the environmental footprint and high cost of manufacturing. They use polymeric adsorbents decorated with affinity ligands that increase the selective capture of the required bio-drug. Current adsorbents originate slow processes with low capacity due to diffusive transport and the uncontrolled heterogeneous distribution of affinity ligands. Only a radical change in purification technologies can reduce the environmental footprint of biopharma industry, and increase productivity, making biopharmaceuticals quickly accessible to all.
PURE envisions the pioneering of precisely functionalised purification nanofibers using principles of scalable biotechnological processes. For the first time, affinity ligands are introduced into convective adsorbents in a site-directed oriented manner and predefined spatial arrangement. Scientific and engineering principles on living organisms are combined to produce the biobased adsorbents of the future, putting Europe in the forefront of sustainable and patient-oriented biopharma. PURE brings together leading scientists and a SME as a highly interdisciplinary team with expertise in biology, chemistry, computational modelling, materials science, bioprocess engineering and applied social sciences. 
The new scientific knowledge and technological paradigm established in PURE have a wide window of opportunities. The scalable bioproduction of fibers with uniform ligand functionalization at predicted sites has never been achieved, and is currently limiting the performance of materials, namely in medical and technical applications. PURE revolutionizes the way advanced functional materials are thought today, and enables a new future.
One crisis, two crises…the subprime crisis and the European sovereign debt problems

Abstract This article explores the link between the subprime crisis and the European sovereign debt crisis. Using a panel data approach, we estimate the impact of the different government interventions aimed at rescuing financial institutions on the significant increase of the costs of public debts as measured by the interest rate spreads with respect to Germany. We show evidence on the existence of a statistically significant link between the two crises embodied by capital injections and government guarantees. More specifically, the two types of government interventions have a negative impact on the cost of the sovereign debts under study. This empirical result can explain why the sovereign debt crisis immediately followed the subprime crisis.
Yield gap analysis of ginger in Champawat district of Uttarakand

To demonstrate and popularize the improved technologies on farmers’ fields to increase yield and fill the gap between recommended practices and farmers practices for ginger production, KVK Champawat conducted front line demonstration on for consecutive six years during kharif 2011 to 2016. Results show that there was wide yield gap between potential yield and demonstration yield due to technology and extension gap. Ginger yield in demonstration plots recorded 38.24 to 53.54% higher over farmers’ practices. It was further observed that in terms of economics higher net return were recorded in demonstration plots as compared to farmers’ practices during all the years. Mean benefit-cost ratio of demonstrated technological intervention was 15.17: 1. On an average technology gap and extension gap were recorded to be 57.13 qha−1 and 37.93 qha−1, respectively. The average technological index was recorded as 32.37%. The yield gap analysis emphasized the need to motivate the farmers through various extension means to adopt economically viable technologies to fill up the wide extension gap.
Search for exact local Hamiltonians for general fractional quantum Hall states

We report on our systematic attempts at finding local interactions for which the lowest-Landau-level projected composite-fermion wave functions are the unique zero energy ground states. For this purpose, we study in detail the simplest non-trivial system beyond the Laughlin states, namely bosons at filling $\nu=\frac{2}{3}$ and identify local constraints among clusters of particles in the ground state. By explicit calculation, we show that no Hamiltonian up to (and including) four particle interactions produces this state as the exact ground state, and speculate that this remains true even when interaction terms involving greater number of particles are included. Surprisingly, we can identify an interaction, which imposes an energetic penalty for a specific entangled configuration of four particles with relative angular momentum of $6\hbar$, that produces a unique zero energy solution (as we have confirmed for up to 12 particles). This state, referred to as the $\lambda$-state, is not identical to the projected composite-fermion state, but the following facts suggest that the two might be topologically equivalent: the two sates have a high overlap; they have the same root partition; the quantum numbers for their neutral excitations are identical; and the quantum numbers for the quasiparticle excitations also match. On the quasihole side, we find that even though the quantum numbers of the lowest energy states agree with the prediction from the composite-fermion theory, these states are not separated from the others by a clearly identifiable gap. This prevents us from making a conclusive claim regarding the topological equivalence of the $\lambda$ state and the composite-fermion state. Our study illustrates how new candidate states can be identified from constraining selected many particle configurations and it would be interesting to pursue their topological classification.
Culture, Creative and Clusters for Incubators

The project will be organized in 3 main phases: 1. Planning and Sharing - In this phase, partners will meet and set the cooperation model, through master plans for the other 2 phases of the project. Partners will be organized by 3 different working groups (Business Model Networking Model and Institutional and territory Links). Inside these groups, the outputs will be analyzed and updated. This will allow the knowledge sharing among partners about the former Med projects outputs and to define approaches and working guidelines for the next phases 2. Model Experimentation - In this phase, partners will test models, methodologies and instruments, based on the already existing outputs and also will create new approaches, based on the working group's proposals. The activities will be focused in an internal impact (actions inside the networks) and in an external impact (actions to reach the market and territory). The actions will allow the definition of ideal incubators model to support creative SMEs and initiatives the communication and ideas sharing among incubators, creative SMEs, cultural sector and territories. Also will allow deepen specific support to specific SMEs or ideas, in order to test the existing tools and methodologies and to contribute to their progress and to promote cultural and creative industry and sector among potential markets and among target stakeholders. 3. Territory Involvement - This phase will focus on the dissemination of the results and outputs to the institutional net that acts in the context of cultural initiatives and also in the creation of Guidelines that can influence the next programming period and can influence new policies to support cultural and creative business. The objective is to define suitable approaches to use with different type of institutions involve institutions in supporting creative ideas projects approved at the Ideas & Projects Factory to set guidelines and proposals for the future.
Endoscopic sleeve gastroplasty for treatment of class 1 and 2 obesity (MERIT): a prospective, multicentre, randomised trial

Background Endoscopic sleeve gastroplasty (ESG) is an endolumenal, organ-sparing therapy for obesity, with wide global adoption. We aimed to explore the efficacy and safety of ESG with lifestyle modifications compared with lifestyle modifications alone. Methods We conducted a randomised clinical trial at nine US centres, enrolling individuals aged 21–65 years with class 1 or class 2 obesity and who agreed to comply with lifelong dietary restrictions. Participants were randomly assigned (1:1·5; with stratified permuted blocks) to ESG with lifestyle modifications (ESG group) or lifestyle modifications alone (control group), with potential retightening or crossover to ESG, respectively, at 52 weeks. Lifestyle modifications included a low-calorie diet and physical activity. Participants in the primary ESG group were followed up for 104 weeks. The primary endpoint at 52 weeks was the percentage of excess weight loss (EWL), with excess weight being that over the ideal weight for a BMI of 25 kg/m2. Secondary endpoints included change in metabolic comorbidities between the groups. We used multiple imputed intention-to-treat analyses with mixed-effects models. Our analyses were done on a per-protocol basis and a modified intention-to-treat basis. The safety population was defined as all participants who underwent ESG (both primary and crossover ESG) up to 52 weeks. Findings Between Dec 20, 2017, and June 14, 2019, 209 participants were randomly assigned to ESG (n=85) or to control (n=124). At 52 weeks, the primary endpoint of mean percentage of EWL was 49·2% (SD 32·0) for the ESG group and 3·2% (18·6) for the control group (p<0·0001). Mean percentage of total bodyweight loss was 13·6% (8·0) for the ESG group and 0·8% (5·0) for the control group (p<0·0001), and 59 (77%) of 77 participants in the ESG group reached 25% or more of EWL at 52 weeks compared with 13 (12%) of 110 in the control group (p<0·0001). At 52 weeks, 41 (80%) of 51 participants in the ESG group had an improvement in one or more metabolic comorbidities, whereas six (12%) worsened, compared with the control group in which 28 (45%) of 62 participants had similar improvement, whereas 31 (50%) worsened. At 104 weeks, 41 (68%) of 60 participants in the ESG group maintained 25% or more of EWL. ESG-related serious adverse events occurred in three (2%) of 131 participants, without mortality or need for intensive care or surgery. Interpretation ESG is a safe intervention that resulted in significant weight loss, maintained at 104 weeks, with important improvements in metabolic comorbidities. ESG should be considered as a synergistic weight loss intervention for patients with class 1 or class 2 obesity. This trial is registered with ClinicalTrials.gov, NCT03406975. Funding Apollo Endosurgery, Mayo Clinic.
Myrtilis durante o I milénio a. C.: uma leitura historiográfica

El presente trabajo analiza la producción historiográfica relativa al I milenio a. C. en Myrtilis (Mértola) entre las primeras fuentes árabes y los trabajos de Estácio da Veiga en 1877. Se analizan fuentes primarias, así como bibliografía crítica sobre datos arqueológicos, fuentes grecolatinas, falsas etimologías y numismas, que tratan la identificación del origen de los fundadores de la ciudad. Esta investigación ha permitido sistematizar las fuentes disponibles para el estudio de Myrtilis y estudiar la evolución de la representación del periodo prerromano antes de las primeras prospecciones arqueológicas en este territorio. Se concluye, asimismo, que la mayor parte de las propuestas presentadas no cambiaron significativamente hasta finales del siglo XIX, y que la escasez de contextos primarios no había permitido responder a algunas cuestiones, tales como la cronología de la primera fase de ocupación.&#x0D; &#x0D; [pt] O presente trabalho incide sobre a produção historiográfica relativa ao I milénio a. C. em Myrtilis (Mértola, Portugal) entre as primeiras fontes árabes e os trabalhos de Estácio da Veiga em 1877. Analisam-se fontes primárias, assim como bibliografia crítica sobre dados arqueológicos, fontes greco-latinas, falsas etimologias e numismas, que tratam a origem dos fundadores da cidade. Esta investigação permitiu sistematizar as fontes disponíveis para o estudo de Myrtilis e avaliar a evolução da representação do período pré-romano antes das primeiras prospecções arqueológicas neste território. Além disso, conclui-se que a maior parte das propostas apresentadas não sofreram alterações significativas até finais do século XIX, e que a escassez de contextos primários não permitiu responder a algumas questões que ainda hoje se colocam, nomeadamente a cronologia da primeira fase de ocupação.
Toy Talk: Simple Strategies to Create Richer Grammatical Input

Purpose The purpose of this initial feasibility study was to determine whether brief instruction in toy talk would change grammatical properties of adult language, specifically 3rd person lexical noun phrase (NP) subjects. Method Eighteen college students participated in the study. The use of 3rd person subjects was examined before and after instruction on toy talk strategies (i.e., talk about the toys, give the item its name ). Change in the input informativeness for tense (i.e., the proportion of verb forms marked for tense out of all verb forms) was also examined, although adults were not instructed on use of tense/agreement morphemes. Results Following instruction, statistically significant increases with large effect sizes were observed for use of 3rd person subjects, lexical NP subjects, and input informativeness for tense (Cohen's d = 1.20, 2.08, and 0.89, respectively). Conclusions These findings demonstrate that young adults can learn these simple strategies with relatively brief instruction, and the use of toy talk also changes the richness of tense/agreement marking in adult language input. Considerations for incorporating toy talk into existing language modeling practices and future plans for evaluating the efficacy of toy talk are discussed.
Circuit Satisfiability and Constraint Satisfaction Around Skolem Arithmetic

We study interactions between Skolem Arithmetic and certain classes of Circuit Satisfiability and Constraint Satisfaction Problems (CSPs). We revisit results of Glaser et al. [16] in the context of CSPs and settle the major open question from that paper, finding a certain satisfiability problem on circuits—involving complement, intersection, union and multiplication—to be decidable. This we prove using the decidability of Skolem Arithmetic. Then we solve a second question left open in [16] by proving a tight upper bound for the similar circuit satisfiability problem involving just intersection, union and multiplication. We continue by studying first-order expansions of Skolem Arithmetic without constants, \((\mathbb {N};\times )\), as CSPs. We find already here a rich landscape of problems with non-trivial instances that are in P as well as those that are NP-complete.
Crystals in protein films: What are they good for?

Abstract Biopolymers were developed comprising 100% renewable resources. The protein-based films were produced by the casting method involving enzymatically mediated cross-linking of the protein network as well as incorporation of KNO 3 . This additive provides a fertilizing effect for biopolymer films in agricultural purposes and is one tool for the modification of physico-chemical properties of protein films. The variation of the parameters, temperature and air humidity, during the drying process of films revealed the opportunity to enhance the film's mechanical performance and to control the crystal morphology of the inner-film crystallized additive, respectively. Drying at room temperature led to small crystals with regular shapes which have been identified to be trigonal phase-III KNO 3 . With higher temperature, the supersaturation level of KNO 3 increased, provoking dendritic shapes. A rise of air humidity consolidated that trend and resulted mainly in the increase of the crystal number. Indeed, further investigation on the stability of the obtained crystal structures within the protein-based has to be performed, as a polymorph transition to orthorhombic phase-II KNO 3 was observed after 48 h that led to an unfavored acicular network.
Failure rate calculation method for high power devices in space applications at low earth orbit

Abstract This paper discusses the universal calculation method for space proton induced failure rate on high power device. High energetic particles can be the reason of power device failure in both terrestrial and space. T-CAD simulation result gives a threshold charge value for the device destruction which is triggered by energetic proton from space. The amount of threshold charge depends on applied voltage for high power device. The probability of charge generation in silicon due to proton penetration is considered as well. This probability function variation depends on the thickness of device and incident energy of proton which studied before at there. Last consideration on this paper is 3.3 kV PiN diode's Single Event Upset Cross section and failure rate which was calculated by proposed method in Low earth orbit environment condition.