SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Advanced intelligent raman system for detection of explosives and harmful substances at urban soft targets

Chemical analysis of unknown samples is a vital measurement in a variety of sectors, from protein characterisation, identifying illicit and counterfeit drugs (est. €3bn cost to the industry), pharmaceutical quality control through to security applications (e.g. detection of explosives). There is a major security requirement is for a new reliable detection method of explosives, especially at soft targets. The ideal solution is a robust in-situ method for rapid non-invasive detection of hazardous materials, including explosives, that is portable and can be located at borders, ports and other sensitive targets around Europe.
The most powerful and promising method being adopted for in-situ observations of suspicious substances to detect explosive is Raman spectroscopy. All molecules provide a unique Raman signature making the method very flexible and effective. However, Raman observations thus far have proven unreliable in the field, due to the very weak signal strength, background fluorescence masking this signal and complicated spectral returns that are difficult to interpret in the field.  
In this project ISI will seek to develop an Advanced Intelligent Raman system (AIRS) that builds on the strengths of the Raman observational approach, and dramatically reduces it current limitations of existing instrumentation. 
AIRS will achieve this by combining three technology development to produce a new portable easy to use chemical identification instrument. Specifically the instrument will use a Time resolved measurement technique using advanced detector technologies to remove the fluorescence and improve the signal to noise of observations. Machine learning analysis tools to interpret instrument returns in the field quickly and efficiently allowing for multiple species to be identified. This will be combined with a new class of static Fourier transform spectrometer to increase the light capture and hence the sensitivity of the instrument.
Enhancement, Sanitation and Production of Local Vines and Wines

The general objective of the project is to recover and add value to local vine species for the production of high quality wines, in compliance with typical features and qualitative characteristics that may enhance their position on domestic and foreign markets. A further objective of the project is that of defining and assessing a “model” for multi-disciplinary action which, through the synergic approach of the various competences of O.U. involved, can become general and applicable to different national and international contexts for the exploitation and enhancement of local genetic resources.
WAFER LEVEL CAPPED SENSOR

A sensor has a die (with a working portion), a cap coupled with the die to at least partially cover the working portion, and a conductive pathway extending through the cap to the working portion. The pathway provides an electrical interface to the working portion.
Implementation of technology for manufacturing innovative furniture edges made of polymer composition on ABS copolymer warp.

The subject of the project is the implementation of product innovation – ABS PLUS furniture edges manufactured on the basis of innovative polymer composition on ABS copolymer warp. As a result of the Rzeszów University of Technology R & D research, an internationally innovative polymer composition on the ABS warp has been developed, allowing to obtain much better physical and chemical properties and functional furniture edges. The research was aimed at eliminating the fundamental technological problems related to the current market outskirts based on ABS or PVC – on the one hand eliminating the fragility of ABS strip and, on the other, gaining flammability at V1 level. ABS PLUS furniture edges manufactured from an innovative mixture on ABS warp are characterised by a clear improvement of performance in the range of extended durability (guarantee 36 months), flammability class V1, increased resistance to mechanical damage, the highest quality, the possibility of working under variable temperature conditions and meeting environmental requirements. The results of the research are covered by the patent application P.412228 ‘Polymer composition on ABS copolymer warp’. The scope of the project includes the purchase of a complete technological line, enabling the production of ABS PLUS furniture edgebands based on an innovative polymer mixture. As a result of the project, product innovation will be introduced, thanks to which the assortment structure of the company will be expanded. The placing on the market of a substantially altered product, which is technologically distinct and of performance against the background of competition offering similar products, will form part of the product range guaranteeing an increase in sales levels both on the domestic and international markets. SA 42799(2015/X), Article 13, 651/2014
Debating single-sex education: separate and equal?

Chapter 1 Single-Sex Classes: Everything That's Old is New Again Chapter 2 Jumping Into the Fray: How to Implement Single-Sex Classes Chapter 3 Bumps Along the Way: Mistakes Made and Lessons Learned Chapter 4 Having it Our Way: Students Speak Out on Single-Sex Classes Chapter 5 Going the Distance: Strategies for Teacher Preparation Chapter 6 Does It Add Up? Single-Sex Classes and Student Achievement Chapter 7 Good New and Bad News: Student Behavior in Single-Sex Classes Chapter 8 For Better or Worse: Classroom Dynamics in Single-Sex Science Classes Chapter 9 We've Always Done it This Way: Single-Sex Classes in Kenya Chapter 10 Now what? Practical implications
Drug release metadynamics simulations with natural micro- and nanostructured excipients

Finding the most efficient and cheapest drug-excipient complex for an increased or modified release kinetics profile of drugs in the body is a current technological challenge in the pharmaceutical industry, especially to improve the treatment of high prevalence and third-country diseases. In this context, it is highly interesting the research on adsorption and diffusion of organic compounds in the surface or internal spaces of clays or related systems. The aim of this proposal is to apply the unique enhanced sampling metadynamics computational tool to properly analyse the processes involved at the nanometric scale, leading not only to rational principles but also to predictions of the pharmaceutical properties. Initially, a computational strategy based on metadynamics simulations will be defined to reproduce known drug release kinetics in drug-clay complexes. A program to automatize all the computations and data management (METADRUG) will be developed after that and in a subsequent step it will be applied to predict unknown release kinetics of relevant drugs from laminar, porous and nanotubular clays. The overall results shall allow determining the clay structural parameters and drug-clay interactions which modulate the release energetics, contributing to the development of new drug delivery systems and novel analysis processed in pharmaceutical technology. The comprehension and accurate prediction of drug increased or modified release phenomena will contribute in this manner to the EU to gain a competitive edge in this area. By means of the proposed project, the fellow will reach a great expertise in the field of Theoretical and Computational Chemistry by strengthening her skills in the use of classical and quantum chemistry methods, acquiring experience with the employment of metadynamics approaches, and learning about programming in Lammps and Plumed. The fellowship will also allow the applicant to develop a promising scientific career to the European level.
Symbolic String Transformations with Regular Lookahead and Rollback

Implementing string transformation routines, such as encoders, decoders, and sanitizers, correctly and efficiently is a difficult and error prone task. Such routines are often used in security critical settings, process large amounts of data, and must work efficiently and correctly. We introduce a new declarative language called Bex that builds on elements of regular expressions, symbolic automata and transducers, and enables a compilation scheme into C, C# or JavaScript that avoids many of the potential sources of errors that arise when such routines are implemented directly. The approach allows correctness analysis using symbolic automata theory that is not possible at the level of the generated code. Moreover, the case studies show that the generated code consistently outperforms hand-optimized code.
IP Capacities for Smart, Sustainable and Inclusive Growth in the MEDiterranean Region

A solid bond between Intellectual Property Rights (IPR), research and innovation constitutes a fundamental pillar for knowledge-based societies. Crucial for the development and competitiveness of start-ups, micro, small and medium-sized enterprises (MSMEs) and entrepreneurs, IPR is, however, the element of the axis most often unknown or overlooked by these groups in business decision-making both in Europe and beyond. Recent studies on firm competitiveness and economic performance highlight that only 9% of SMEs make use of IPR in Europe (against 40% of large companies). Yet small firms owning IPR perform better than those that do not (increased reputation, strengthening of long-term business prospects and increased turnover). In the Euro-Mediterranean area, changing this pattern of low interest/access to IPR is critical to help regions of both shores of the basin achieve smart, sustainable and inclusive growth. IPMED intends to contribute to that change by helping local authorities understand how they can better support entrepreneurs in accessing, using and optimizing the growth potential of IPR, and enhancing the IPR of young entrepreneurs.
The role of Athyrium distentifolium in reduction of soil acidification and base cation losses due to acid deposition in a deforested mountain area

The tall fern (Athyrium distentifolium Tausch ex Opiz) forms large stands in many deforested sites in Central European mountains. In the present study, we want to demonstrate that the effect of ferns on the leaching of nutrients is the same at low and high nitrogen (N) deposition. Free-tension lysimeters with growing ferns, and some with bare forest soil were installed in field conditions in 2006. We monitored the chemistry of lysimetric water at ambient and enhanced (plus 50 kg N ha-1) levels of N deposition during five growing seasons. Results indicate that during the growing seasons ferns slightly decreased of acidity and conductivity of lysimetric water and substantially reduced losses of base cations (Ca2+ and Mg2+). The concentration of leached base cations was three to seven times higher from bare forest soil than from lysimeters with ferns. Higher N accumulation in fern biomass coincides with lower contents of leached N in lysimetric water. The reduced losses of base cations were due to the ability of Athyrium to absorb and accumulate nutrients in large amounts in living biomass and in dead undecomposed plant matter and particularly in below-ground biomass.
COMPOUNDS THAT MODULATE HSP90 ACTIVITY AND METHODS FOR IDENTIFYING SAME

The present invention relates to compositions and methods related to inhibitors of Hsp90, including substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for preventing or treating hyperproliferative disorders, such as cancer, in a subject in heed thereof comprising administering to the subject a substituted triazole compound of the invention, or a composition comprising such a compound. The invention further provides methods for designing and identifying inhibitors of Hsp90.
Quarta dimensão da animação de fantoches

Number_reference_aid_programa: SA.41471(2015/X) Objetivo do auxílio público: Artigo 25.º do Regulamento (CE) n.º 651/2014, de 17 de junho de 2014, que declara certas categorias de auxílios compatíveis com o mercado interno, em aplicação dos artigos 107.º e 108.º do Tratado É isso mesmo. UE L 187/1 de 26.6.2014). O tema do projeto é realizar trabalhos de pesquisa e desenvolvimento industrial no campo da implementação completa da tecnologia de captura de movimento para as necessidades de animação de fantoches em tempo de parada. A tecnologia será definida como: É O SMODO. Os trabalhos previstos incluirão, entre outros, a otimização de: algoritmos, métodos de rastreamento, facilidade de utilização, minimizando o custo do produto final, aumentando a eficiência do sistema, bem como unificando todos os elementos em um todo coerente, garantindo a implementação abrangente do produto do lado visual (caixa de produtos com conteúdo completo). O resultado do projeto será uma tecnologia caracterizada pela novidade em escala nacional e global. As soluções tecnológicas que serão utilizadas não são utilizadas em nenhum dos sistemas anteriormente utilizados que suportam o processo de animação de fantoches. A inovação emergirá em domínios como: aquisição de movimento de carateres sem necessidade de modelos estatísticos de movimento (em contraste com sistemas clássicos de captura de movimento), métodos de codificação e identificação de marcadores fixados em esqueletos de boneca, calibração de parâmetros de câmera de rastreamento usando a estrutura da técnica de movimento, método de validação automática da correção da operação e adaptação do sistema de rastreamento a condições externas. A tecnologia acelerará o processo de animação de lapso de tempo, reduzirá os planos de filme, eliminará a iluminação cara e reduzirá os custos de pessoal e equipamentos. Simplificará a fase de pós-produção.
The involvement of working memory and inhibition functions in the different phases of insight problem solving

In this article, the involvement of working memory capacity and inhibition functions in different phases of insight problem solving is investigated, by employing a method of separating the different phases of insight problem solving directly, on the basis of the subjects' oral reports. Two experiments are described. In Experiment 1, 87 subjects were administered a series of working memory span tasks and inhibition tasks, as well as a verbal insight problem. In Experiment 2, 119 subjects were administered the same working memory span tasks and inhibition tasks as in the first experiment, as well as a spatial insight problem. Several conclusions can be drawn from this study. First, the insight problem-solving process can be divided into several relatively independent phases, including an initial searching phase and a restructuring phase. Second, executive functions, as measured by working memory capacity, influence mainly the initial searching phase, rather than the restructuring phase. Third, inhibition functions play important but complex roles in restructuring, and sometimes could influence restructuring in contradictory ways simultaneously. The implications and value of this study are discussed further.
Benefits of curriculum renewal: The Stellenbosch University physiotherapy experience

Background. Driven by a changing healthcare environment, the Division of Physiotherapy (Stellenbosch University) reduced core content and adopted a multimodal approach to teaching and learning. The benefits of curriculum renewal, however, are seldom investigated despite ongoing internal appraisal. Evaluation of the BSc Physiotherapy programme was considered incomplete without determining the worth of the programme. Objectives. To determine whether there was a change in students’ perception of the impact of the programme on personal development; and whether the programme prepared them for community service. Methods. A descriptive comparative desktop analysis was conducted in which the data from the Faculty’s Programme Evaluation process were compared between students enrolled in the old curriculum (2006) and students enrolled in the new curriculum (2011) using pooled data and t -tests to compare responses between the two groups. A level of significance was set at p &lt;0.05. Results. A significant increase in scores was noted for various graduate attributes developed as a result of the programme, such as critical thinking, clinical reasoning, communication and sourcing information ( p &lt;0.01). Similarly, students scored their perceptions related to programme structure significantly higher ( p &lt;0.01). No change was reported regarding students’ ability to maintain a balance between studies and other activities. Scores pertaining to their perception of readiness for community service or professional practice remained the same with both cohorts believing they were well prepared. Conclusion. The renewed format seemed to benefit students greatly in assisting the development of graduate attributes. Students were significantly more satisfied with the structure of the renewed curriculum and – despite extensive changes – the principles-based multimodal approach to teaching and learning was perceived as effective for preparing students for community service. Programmes undertaking curriculum renewal should not only focus on the curriculum content but also develop a variety of learning opportunities to facilitate the development of graduate attributes. The next cycle of evaluation should however reflect on clinical practice.
Channel Sensing without Quiet Period for Cognitive Radio Systems: A Pilot Cancellation Approach

The cognitive radio (CR) systems usually arrange for the quiet period to detect the primary user (PU) effectively. Since all CR users do not transmit any data during quiet period, the interference caused by other CR users can be prevented in the channel sensing for PU detection. Even though the quiet period improves the PU detection performance, it degrades the channel utilization of CR system. To cope with this problem, we propose a channel sensing scheme without quiet period, which is based on the pilot cancellation, and analyze its performance. The numerical results show that the proposed scheme highly outperforms the existing PU detection schemes.
Load-adjusting device for a vehicle.

The invention relates to a load-adjusting device, in particular for a vehicle, having an actuating element (204) whose position determines the power of a drive motor and is acted upon by a restoring spring (205) in the idling control direction, the position of the actuating element (204) being adjustable at least in the idling region of the drive motor with the aid of an actuating drive (221) which can be driven by a control device, and, when the actuating drive is not activated, the actuating element being held in the idling region of the drive motor in a specific position which determines increased idling (ELL) by resting against a stop (208) which is spring-loaded counter to the idling control direction. The object of the invention is to avoid, when the actuating drive is activated, the problems which are associated with the spring force of the spring of the stop, which force is to be overcome in the idling region. This object is achieved according to the invention in that when the actuating drive (221) is activated, the spring-loaded stop (208) is held by a restoring element (207) in a position in which it is pulled back against the effect of its spring (210) and releases the actuating element (204) over its entire actuating range. In the preferred embodiment, this restoring element (207) is an electromagnet. <IMAGE>
MOLECULAR ANTIGEN ARRAY

The present invention is related to the fields of molecular biology, virology, immunology and medicine. The invention provides a composition comprising an ordered and repetitive antigen or antigenic determinant array. The invention also provides a process for producing an antigen or antigenic determinant in an ordered and repetitive array. The ordered and repetitive antigen or antigenic determinant is useful in the production of vaccines for the treatment of infectious diseases, the treatment of allergies and as a pharmaccine to prevent or cure cancer and to efficiently induce self-specific immune responses, in particular antibody responses.
Models of the yield curve and the curvature of the implied forward rate function

Abstract We examine several alternative models of the UK gilt yield curve using daily data for the period 12 July 1996–10 February 2010. We select the best models according to two criteria: low out of sample errors in pricing bonds and low curvature of the implied forward rate curve function. We suggest additions to some of the models that significantly improve their performance. Some of the new models out perform those typically used by the central banks. In particular this paper suggests that the model used by the Canadian Central Bank which both outperforms other models and is particularly easy to estimate, is well suited to the UK gilt market.
Educazione e cura dei bambini e delle bambine ai tempi del coronavirus. La risposta dei servizi educativi italiani

L’articolo riflette su come in Italia sia stata affrontata la crisi sanitaria causata dal Covid-19 a livello dei servizi educativi per l’infanzia. Dopo aver ricostruito il quadro politico e normativo nazionale, l’attenzione si concentra sulla realtà toscana. L’obiettivo è quello di illustrare da un lato alcune esperienze nella Regione Toscana durante il lockdown per garantire una continuità nella relazione educativa a distanza e dall’altro mostrare come i servizi educativi toscani hanno reagito alla ripresa dell’anno educativo 2020-21. Il primo aspetto è ricostruito attraverso una ricognizione di materiali collocati in rete, mentre il secondo aspetto è documentato attraverso i risultati di un’indagine condotta da chi scrive e che ha coinvolto i servizi educativi della Cooperativa Arca. Se ne ricava un quadro dinamico che mette in luce gli sforzi del personale educativo sia nella gestione delle routine sia nella ricerca di modalità inedite di relazione con le famiglie.
New Active HIV-1 Protease Inhibitors Derived from 3-Hexanol: Conformation Study of the Free Inhibitors in Crystalline State and in Complex with the Enzyme

Four novel linear non-peptidic HIV-1 protease inhibitors derived from 2,5-diamino-1,6-diphenyl-3-hexanol were synthesized and characterized. All of them exhibit tight binding to HIV-1 protease, with inhibition constants K(i) in the range 20 pm-5 nm. The investigated inhibitors were crystallized, and their crystal structures were determined by X-ray diffraction. In all cases, the conformations found in the crystalline state differ significantly from the conformations obtained by computational docking of the inhibitor in the binding cleft of native HIV-1 protease. Owing to the prevalence of hydrophobic substituents in all these inhibitors, the conformational mobility in water solution is restricted to their compact forms. The spectrum of low-energy conformations in solution dramatically changes during the formation of inhibitor crystals (phenyl ring stacking as a leading motif) or during the formation of a complex with HIV-1 protease (elongated conformation suitable to fit the enzyme pockets as a factor responsible for tight binding). High conformational flexibility and low conformational stress in the molecules of these inhibitors most likely increase their biological activity in comparison with more rigid compounds.
Projeto de produtização e internacionalização da Badrap Oy

A Badrap Oy produz, oferece e vende serviços de nuvem que permitem que empresas e indivíduos identifiquem suas dependências de TI e recebam informações sobre riscos e violações de segurança. Com este projeto de desenvolvimento e internacionalização, a badrap Oy aumenta a sua capacidade de satisfazer a necessidade internacional ao produzir as suas inovações. Além disso, a empresa visa novos mercados e explora novas oportunidades de negócio.