SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Linguistic Marginalities: Becoming American without Learning English

People living in the United States but unable to speak English are often portrayed as marginal and isolated —socially, economically, and geographically. Such narratives present the learning of English as central to becoming American and widely claim that earlier immigrants quickly acquired English. This paper counters such stereotypes. Wilkerson and Salmons present a case study of the extent to which one group of monolingual immigrants lived literally and figuratively on the margins. They draw qualitative and quantitative data from southeastern Wisconsin, especially one township, Hustisford. In 1910, 24 percent of Hustisford residents reported being German monolingual, 35 percent of those American-born. Contrary to assumptions of economic marginality, in this region such monolinguals were not only housewives and farmhands but also craftsmen, tradesmen, teachers, and members of the clergy. Another stereotype is that monolinguals were geographically marginal, but they find them living interspersed with bilinguals and English monolinguals. Nor were they socially marginal, as church records point to a broadly German-dominant but overwhelmingly bilingual community, where numerous Anglo-Americans became highly proficient in German. Even schools were hardly the powerful tools of English learning they are often portrayed as being. Despite all this, Hustisford and similar communities presented themselves as hyperpatriotic Americans. These monolingual immigrants, in short, were not marginal in the usual senses.
Architecture for an internet for everybody

RIFE addresses the major societal challenge of providing affordable Internet access to those who cannot afford it by solving the technological challenge to increase the efficiency of the underlying transport networks and the involved architectures and protocols. The RIFE solution will harness unused transmission capacity, combined with placing content caches and service functionality closer to the user and will use heterogeneous transmission opportunities that range from localized mesh and home networks over well-connected ISP backhauls to scarce satellite resources. RIFE will build upon recent advances on information-centric and delay-tolerant networking by developing optimized dissemination strategies for the involved transport networks, unified within a novel communication architecture that will provide clear abstractions to application developers. We will develop, deploy and showcase our solution in a real-life setting within a large-scale community network in Spain, demonstrating the technology and economic opportunities that the RIFE platform provides. We will complement our real-life testbeds with emulation scenarios to enable the evaluation of our novel resource management schemes at scale, while integrating with our prototype platform. On the economic side, we will develop business opportunities for local authorities as well as backhaul network providers to create a sustainable value chain by introducing virtual network operators that utilize the under-used capacity in a new business relationship with local customers, enabling novel and often socially-driven business models. The involvement of a technology, equipment, as well as satellite and community network provider will allow for maximizing the commercial exploitation of RIFE within real deployments and towards standard communities within the IETF/IRTF and beyond, placing RIFE in the centre of a growing community of practitioners that all share the same goal: making the Internet affordable to everybody!
Public Organisations Transform Energy Transition

POTEnT innovatively addresses a key challenge for European cities and regions: how to achieve more carbon reduction by harnessing the potential of direct and local action by citizens and communities.The need is both great and urgent. The EU is committed by international treaty to achieve ambitious carbon reduction targets.  

Regional and local authorities can provide a positive alternative to the market-based provision of energy services. The POTENTIAL lies in their local connections, opportunities and accountability
However, they face many challenges in becoming actors in the energy market. First, they need to develop legal mechanisms, attract investment, acquire skills, engage communities. Second, many market-regulations are made at Member State level, so tailor-made solutions are required. 

The project’s objective is to reduce carbon emissions faster than “Business As Usual” through more and better energy services provided by local and regional authorities. 8 partners will:
* analyse partners’ plans through two Thematic Events and eight Mentoring Days,
* identify good practices that will improve these plans, studying them through Study Visits, importing them via special workshops and Regional Action Plans.
* develop/improve public Energy Services Companies (ESCos) and increasing their “market-share”,
* build the capacity of all relevant public authorities including ERDF Managing Authorities,
* increase investments in low carbon projects, and inspire/empower local decision-makers and communities. 

The project’s main outputs will be focused on new energy transition solutions through: 
* New projects to increase investment in low carbon projects, inspire/empower local decision-makers and communities to achieve higher levels of carbon reduction, 
* Improved governance by delivering policies to develop/improve public Energy Services Companies and transform existing mechanisms into "future-fit" organisations that will have a bigger impact on carbon reduction.
Biocompatible nanoparticles for t cell targeted sirna delivery as novel asthma therapy

The aim of this proposal is to engineer biocompatible nanoparticles that deliver short interfering RNA (siRNA) to activated T cells (ATCs) for the downregulation of the Type 2 T helper cell (Th2) transcription factor GATA-3. By downregulating GATA-3 with siRNA, which regulates the secretion of proinflammatory cytokines in chronic inflammatory diseases such as asthma, the activation of their downstream inflammatory cascades can be prevented. However, T cells are hard-to-transfect cells which are not readily accessible for nucleic acid based therapeutics. I am the first to have demonstrated successful and targeted siRNA delivery to ATCs ex vivo and in vivo for specific GATA-3 knockdown without delivering siRNA to naive T cells. Thus, I can avoid general immune suppression. This was achieved by engineering targeted siRNA delivery systems based on low molecular weight polyethylenimine (LMW-PEI) which form nanoparticles with siRNA and successfully deliver the latter to ATCs. The targeting approach was realized by coupling transferrin to LMW-PEI and by optimizing the coupling chemistry. I have demonstrated specific delivery to ATCs in a mouse model of allergic asthma and have screened siRNA sequences for efficient GATA-3 knockdown. The nanoparticles were administered locally to the lung to prevent the first-pass effect in the liver. The LMW-PEI based nanocarriers were very well tolerated in healthy animals, however, potentially caused additional proinflammatory effects in the asthma model. 
Therefore, I will engineer nanocarriers that do not only specifically deliver siRNA to ATCs but are also biocompatible in a diseased state of the lung. I will use oligospermines, which are tetramers and octamers of spermine, an endogenous polyamine, and apply the optimized coupling strategy to target the spermine based nanocarriers to ATCs for therapeutic GATA-3 knockdown. To obtain clinically relevant formulations, I will produce inhalable powders of these nanocarriers.
Seroprevalence of Hepatitis E Among Hemodialysis Patients: a Report From Hamadan, Iran

Previous studies have documented a high prevalence of hepatitis E among patients undergoing maintenance hemodialysis. Available studies reporting on the seroprevalence of hepatitis E in hemodialysis patients in Iran, an endemic region for the disease, are sparse.The present study aimed to determine the prevalence rate of anti-hepatitis E antibody in hemodialysis patients in Hamadan, Iran.In this cross-sectional study, all 153 consecutive patients undergoing hemodialysis in two centers were enrolled. Patients' demographic and clinical data were collected, using a standard questionnaire and from medical records. Serum immunoglobulin G concentrations against hepatitis E were determined using the enzyme linked immunosorbent assay method.Thirty patients (19.2%), were seropositive. Seropositive patients were not significantly different from seronegative patients, with regard to age, sex, level of education, access to filtered water, and duration and frequency of hemodialysis. The proportions of patients with hepatitis B, C, and HIV infection were comparable between the two groups.One in five patients undergoing maintenance dialysis in Hamadan is seropositive for hepatitis E immunoglobulin G antibody. Future studies are needed to investigate the factors contributing to the observed high prevalence rate and the possibility of parenteral transmission of hepatitis E.
COMPARISON OF THE PRECISION OF MEASUREMENTS IN THREE TYPES OF MICROPIPETTES ACCORDING TO NCCLS EP5-A2 AND ISO 8655-6

Micropipettes or piston pipettes are used to make most volume measurements in fields such as health, chemistry, biology, pharmacy and genetics. Laboratories must ensure that results obtained using these instruments are reliable; therefore, it is necessary to calibrate micropipettes. Before the start of the calibration process, we must check the precision of measurements. The objective of this work is to compare several methods for calculating the precision of three kinds of micropipettes according to the reference value in ISO 8655-6. The medical tests will not have accurate results, if the volume of the liquid doesn’t transfer precisely by micropipettes. Thus, the physician might potentially face problems in the disease diagnosis and its control. In the NCCLS EP5-A2, there is a method to specify and assess the precision of micropipettes by using CV (Coefficient of Variation). Also there are other methods to estimate and test the CV theory, in the formal statistics texts which could be applied to assess the micropipettes precision. In this research we evaluate the precision of lab micropipettes. Three brands of micropipettes, A, B and C are assigned to measure the distilled water mass by using accurate scale which is accurate up to 10-6 to measure 50-gram weights. The experimental environment is a metrology lab which is approved by Iran Standard and Industrial Researches Organization. A technician sampled at the beginning of the experiment and then after 2 hours, the same technician repeated the sampling. Overall, each micropipette is used to measure 40 times with 10-repeat times for single measurement in 28 work days. Common statistical methods are used to estimate and test the CV. Point estimation of CV for micropipettes A, B and C were 0.50%, 0.64% and 1.56%, respectively. Furthermore, the upper limit of 95% confidence bounds for these three micropipettes using the exact method were 0.53%, 0.69% and 1.65%, respectively. Micropipette A met the ISO 8655-6 standard level, but micropipettes B and C did not. On average, measurement errors in micropipettes B and C were respectively 30% and 3.11 times more than micropipette A. By using the approach of CLS EP5-A2 and confidence interval for CV, precision of the three micropipettes were compared. Only one of them met the ISO 8655-6 standard level, but the others failed.
Usefulness of a single-item measure of depression to predict mortality: the GAZEL prospective cohort study

It remains unknown whether short measures of depression perform as well as long measures in predicting adverse outcomes such as mortality. The present study aims to examine the predictive value of a single-item measure of depression for mortality.A total of 14,185 participants of the GAZEL cohort completed the 20-item Center-for-Epidemiologic-Studies-Depression (CES-D) scale in 1996. One of these items (I felt depressed) was used as a single-item measure of depression. All-cause mortality data were available until 30 September 2009, a mean follow-up period of 12.7 years with a total of 650 deaths.In Cox regression model adjusted for baseline socio-demographic characteristics, a one-unit increase in the single-item score (range 0-3) was associated with a 25% higher risk of all-cause mortality (95% CI: 13-37%, P<0.001). Further adjustment for health-related behaviours and physical chronic diseases reduced this risk by 36% and 8%, respectively. After adjustment for all these variables, every one-unit increase in the single-item score predicted a 15% increased risk of death (95% CI: 5-27%, P<0.01). There is also an evidence of a dose-reponse relationship between reponse scores on the single-item measure of depression and mortality.This study shows that a single-item measure of depression is associated with an increased risk of death. Given its simplicity and ease of administration, a very simple single-item measure of depression might be useful for identifying middle-aged adults at risk for elevated depressive symptoms in large epidemiological studies and clinical settings.
ENTITE ELECTRONIQUE A COMPOSANT ALIMENTE PAR COUPLAGE ELECTROMAGNETIQUE INTERNE

La présente demande concerne une entité électronique comportant un corps (100) et un module (200) encarté dans ce corps (100), un microcircuit (105) et une source de courant continu (104) faisant partie du corps (100) et un composant électronique (201) faisant partie du module (200) et accessible depuis l'extérieur, ce composant électronique (201) étant connecté électriquement au microcircuit (105) et devant être alimenté en courant continu par la source de courant continu (104), et le corps (100) comportant une première antenne (103) connectée à la source de courant continu (104) au travers d'un oscillateur (106) et le module (200) comportant une seconde antenne (203) connectée à ce composant électronique (201) au travers d'un circuit redresseur (202), ces première antenne (103) et seconde antenne (203) étant électro-magnétiquement couplées, assurant une alimentation radiofréquence sans fil du composant électronique (201) du module (200) par la source de courant continu (104) du corps (100).
Pengurusan Konflik dan Ciri Kepimpinan Pelajar Berdasarkan Jantina : Satu Kajian di SMK Syed Ahmad, Tambun Tulang, Arau, Perlis

The purpose of this research is to study is to investigate the relationship between leadership and styles of managing conflict based on gender among students in SMK Syed Ahmad, Tambun Tulang, Arau, Perlis. Thus, either the significant exist between gender and styles of managing conflict or leadership were carry out in this research. 140 form two and form four students from SMK Syed Ahmad, Tambun Tulang, Arau, Perlis served as the unit of analysis for the data generated. The items for leadership traits are built based on the cluster of autocratic, democratic and laissez faire as introduced by leadership scholars and was modified into leadership based on task (task oriented), based on relationship (relationship oriented) and passive. As for styles of managing conflict, Kilmann-Thomas Model (1974,1977,1978) was based upon. The hypothesis were then tested using t-test and Pearson Correlation Test. All hypothesis were test for significant level of p=0.05. From the test done, it is stated that there is no significant between gender with leadership and style of managing conflict. A significant finding is detected between leadership based on relationship oriented with styles of managing conflict of collaboration and competition. Thereby, the finding implied towards secondary school administration and to whom it may concern. The connotation of this study is that students should be upgraded with leadership and styles of managing conflict especially those who live in the rural area.
Linking X-ray AGN with dark matter halos: a model compatible with AGN luminosity function and large-scale clustering properties

Our goal is to find a minimalistic model that describes the luminosity function and large-scale clustering bias of the X-ray-selected AGN in the general framework of the concordance LCDM model. We assume that a simple population-averaged scaling relation between the AGN X-ray luminosity L_X and the host dark matter halo mass M_h exists. With such a relation, the AGN X-ray luminosity function can be computed from the halo mass function. Using the concordance LCDM halo mass function for the latter, we obtain the M_h-L_X relation required to match the redshift-dependent AGN X-ray luminosity function known from X-ray observations. We find that with a simple power-law-scaling M_h \propto L_X^\Gamma(z), our model can successfully reproduce the observed X-ray luminosity function. Furthermore, we automatically obtain predictions for the large-scale AGN clustering amplitudes and their dependence on the luminosity and redshift, which seem to be compatible with AGN clustering measurements. Our model also includes the redshift-dependent AGN duty cycle which peaks at the redshift z ~ 1, and its peak value is consistent with unity, suggesting that on average there is no more than one AGN per dark matter halo. For a typical X-ray-selected AGN at z ~ 1, our best-fit M_h-L_X scaling implies low Eddington ratio L_X/L_Edd ~ 10^{-4}-10^{-3} (2-10 keV band, no bolometric correction applied) and correspondingly large mass growth e-folding times, suggesting that the typical X-ray AGN are dominantly fueled via relatively inefficient 'hot-halo' accretion mode.
Cross-Sectional Study of Sleep Quantity and Quality and Amnestic and Non-Amnestic Cognitive Function in an Ageing Population: The English Longitudinal Study of Ageing (ELSA)

The aim was to investigate the association between sleep disturbances and cognitive function in younger and older individuals from an ageing population.3,968 male and 4,821 female white participants, aged 50 years and over, from the English Longitudinal Study of Ageing (ELSA) were studied. Information on sleep quality and quantity as well as both amnestic (memory, ACF) and non-amnestic (non-memory, nACF) function was available at Wave 4 (2008). Analysis of covariance was used to evaluate the relationship between sleep and cognitive function.After adjustment for multiple confounders in the younger group (50-64 years) duration of sleep explained 15.2% of the variance in ACF (p = 0.003) and 20.6% of nACF (p = 0.010). In the older group (65+ years) the estimates were 21.3% (p<0.001) and 25.6% (p<0.001), respectively. For sleep quality, there was a statistically significant association between sleep quality and both ACF (p<0.001) and nACF (p<0.001) in the older age group, but not in the younger age group (p = 0.586 and p = 0.373, respectively; interaction between age and sleep quality in the study sample including both age groups: p<0.001 for ACF and p = 0.018 for nACF). Sleep quality explained between 15.1% and 25.5% of the variance in cognition. The interaction with age was independent of duration of sleep. At any level of sleep duration there was a steeper association between sleep quality and ACF in the older than the younger group.The associations between sleep disturbances and cognitive function vary between younger and older adults. Prospective studies will determine the temporal relationships between sleep disturbances and changes in cognition in different age groups.
Transformation of strictosamide to vincoside lactam by acid catalysis

To identify the structure of the acid-catalyzed product of strictosamide and explore the reaction mechanism.The acid-catalyzed reaction process of strictosamide was monitored by HPLC, and a macroporous resin was used to purify the reaction solution. The structure of the product was confirmed by MS, NMR, and ROESY spectra.The acid-catalyzed transformation yield from strictosamide to vincoside lactam was 52%.The reaction mechanism of the transformation from strictosamide to vincoside lactam may be related to the stability of the three-dimensional configuration of the compound. These results offer a new way to obtain vincoside lactam from the widely distributed indole alkaloid strictosamide by acid-catalysis.
DOWNHOLE ASSEMBLY FOR SELECTIVELY SEALING OFF A WELLBORE

Downhole assemblies and methods for isolating a wellbore. A downhole tool can include a body having a bore or flowpath formed therethrough, and one or more sealing members disposed therein. The one or more sealing members can include an annular base and a curved surface having an upper face and a lower face, wherein one or more first radii define the upper face, and one or more second radii define the lower face, and wherein, at any point on the curved surface, the first radius is greater than the second radius. The sealing members can be disposed within the bore of the tool using one or more annular sealing devices disposed about the one or more sealing members.
Research on Supportability Evaluation Simulation Arithmetic of Naval Gun Equipment Based on Mission

Naval gun equipment supportability simulation is typical discrete events dynamic simulation. A kind of simulating principle was set up based on equipment parameter and using regulation parameter by using the theory of Monte-Carlo sampling, mathematical statistics and computer simulation. Simulation arithmetic including mission, support organization and maintenance process were set up based on the simulation principle. Operational availability, probability operational readiness and mission completion success probability were set up. The examples show that the evaluation arithmetic and model are in accord with the facts, and reasonable and valid. It not only can evaluate mission success and readiness for equipment operational department, but also can exactly solve evaluation of spare parts in war time or peace time. It has far-reaching practical value and meaning.
Dysregulated FOXO transcription factors in articular cartilage in aging and osteoarthritis

Aging is a major risk factor for osteoarthritis (OA). Forkhead-box class O (FoxO) transcription factors regulate mechanisms of cellular aging, including protein quality control, autophagy and defenses against oxidative stress. The objective of this study was to analyze FoxO transcription factors in normal, aging and OA cartilage.Knee joints from humans ages 23-90 and from mice at the age of 4-24 months and following surgically induced OA were analyzed for expression of FoxO proteins. Regulation of FoxO protein expression and activation was analyzed in cultured chondrocytes.Human cartilage expressed FOXO1 and FOXO3 but not FOXO4 proteins. FOXO1 and FOXO3 were more strongly expressed the superficial and mid zone as compared to the deep zone and were mainly localized in nuclei. During human joint aging, expression of FOXO1 and FOXO3 was markedly reduced in the superficial zone of cartilage regions exposed to maximal weight bearing. In OA cartilage, chondrocyte clusters showed strong FOXO phosphorylation and cytoplasmic localization. Similar patterns of FOXO expression in normal joints and changes in aging and OA were observed in mouse models. In cultured chondrocytes, IL-1β and TNF-α suppressed FOXO1, while TGF-β and PDGF increased FOXO1 and FOXO3 expression. FOXO1 and FOXO3 phosphorylation was increased by IL-1β, PDGF, bFGF, IGF-1, and the oxidant t-BHP.Normal articular cartilage has a tissue specific signature of FoxO expression and activation and this is profoundly altered in aging and OA in humans and mice. Changes in FoxO expression and activation may be involved in cartilage aging and OA.