SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Drug-induced interstitial lung disease during cancer therapies: expert opinion on diagnosis and treatment

Drug-induced interstitial lung disease (DIILD) is a form of interstitial lung disease resulting from exposure to drugs causing inflammation and possibly interstitial fibrosis. Antineoplastic drugs are the primary cause of DIILD, accounting for 23%-51% of cases, with bleomycin, everolimus, erlotinib, trastuzumab-deruxtecan and immune checkpoint inhibitors being the most common causative agents. DIILD can be difficult to identify and manage, and there are currently no specific guidelines on the diagnosis and treatment of DIILD caused by anticancer drugs.To develop recommendations for the diagnosis and management of DIILD in cancer patients.Based on the published literature and their clinical expertise, a multidisciplinary group of experts in Italy developed recommendations stratified by DIILD severity, based on the Common Terminology Criteria for Adverse Events.The recommendations highlight the importance of multidisciplinary interaction in the diagnosis and management of DIILD. Important components of the diagnostic process are physical examination and careful patient history-taking, measurement of vital signs (particularly respiratory rate and arterial oxygen saturation), relevant laboratory tests, respiratory function testing with spirometry and diffusing capacity of the lung for carbon monoxide and computed tomography/imaging. Because the clinical and radiological signs of DIILD are often similar to those of pneumonias or interstitial lung diseases, differential diagnosis is important, including microbial and serological testing to exclude or confirm infectious causes. In most cases, management of DIILD requires the discontinuation of the antineoplastic agent and the administration of short-term steroids. Steroid tapering must be undertaken slowly to prevent reactivation of DIILD. Patients with severe and very severe (grade 3 and 4) DIILD will require hospitalisation and often need oxygen and non-invasive ventilation. Decisions about invasive ventilation should take into account the patient's cancer prognosis.These recommendations provide a structured step-by-step diagnostic and therapeutic approach for each grade of suspected cancer-related DIILD.
SOLVENT PULPING OF BIOMASS

A method and apparatus for solvent pulping of cellulose containing biomass, comprising: a) at least one atmospheric steaming vessel (22) having a first outlet, b) at least one super-atmospheric impregnation vessel (28) operatively connected to the first outlet, and having a second outlet, c) a solvent delignification reactor (80) operatively connected to b) and capable of operating at a pressure of 350 psig or more, and having a third outlet; and a plurality of series connected pressure diffusers (51).
Importance of satisfaction with food for older adults’ quality of life

Purpose – The purpose of this paper is to examine the relationships among satisfaction with food-related life (SWFL), perceived foodservice quality, and quality of life for older adults. Design/methodology/approach – A survey done using face-to-face interviews of older adults residing in long-term care facilities. A total of 238 older adults participated in this study. Findings – The results showed that perceived foodservice quality had a strong association with SWFL; SWFL had a significant positive association with quality of life; perceived foodservice quality positively related to quality of life. Increased SWFL would improve quality of older adults. Research limitations/implications – This study has limitations related to convenience sample. Different sampling could help with generalization of results. Practical implications – Foodservice managers in long-term care facilitates should try to maximize food and service qualities for residents because improving food and service quality improves their quality of life. For example, offering a variety of menus to allow older adults to enjoy food and improve their SWFL. Originality/value – This study emphasized that food was important to older adults and helped determine quality of life for them. SWFL was rarely empirically examined in the previous research.
IMPROVED WASHING METHOD I

The invention relates to an aqueous detergent solution in a device for cleaning soiled textile substrates, said solution containing a plurality of water-insoluble solid particles which consist of organic polymer material and carry polyalkoxy groups on their surface.
Properties across dimensions: an atomistic computational study of bismuth ferrite surfaces and nanocrystals

Bismuth ferrite (BFO) is one of the few multiferroic materials at room temperature. It is of interest for use in memory elements, spintronic and photovoltaic systems, to name but a few. In all applications, the use of BFO thin films and nanoparticles is being greatly investigated, due to their greater fatigue resistance and larger polarization at modest electric fields with respect to the bulk. However, reducing the dimensionality of BFO can lead to surprising and so far unexplained behaviour. For example, recent experiments have reported the existence of a surface “skin” above bulk-truncated BFO, with different lattice parameters and phase transitions than the underlying bulk. This surface skin layer exhibits strikingly different properties from the bulk, since it is ferroelastically and ferroelectrically dead. It is thus of paramount importance, for practical applications of BFO, to understand how 2D structures (like thin films) and 1D structures (like nanocrystals) differ in their multiferroic behaviour from the relatively well understood bulk phase. Since surfaces are dominant in these two classes of systems, a good atomistic understanding of low-energy surfaces and their stability in the environment is needed. Thus, we propose a two-year project with the overall aim of studying the atomistic structure and the magnetic and polarization properties of BFO thin films and nanocrystals using using ab initio methods (density functional theory with ab initio thermodynamics).
The Effect of Jatropha Curcas Seed Meal on Growth Performance and Internal Organs Development and Lesions in Broiler Chickens

The meal of Jatropha curcas (JCM) seed is a by-product of the biofuel industry and may potentially to be used as animal feed. However, its toxicity has prevented its utilization in animal nutrition mainly due to its high concentration of phorbol esters. This study was conducted to evaluate the effects of the dietary inclusion of JCM on the growth performance, feed digestibility and internal organs development of broilers. Thirty two 48-d-old Ross 308 broiler chickens housed in 16 pens (2 birds/pen) were used in this study. Birds were randomly allocated to dietary treatments comprising four JCM levels (negative control, 25, 50, or 100 g JCM/kg of diet) for four weeks. Results showed that increasing levels of JCM had a negative impact on broiler performance, reducing live weight, weight gain, and feed intake. Treatments led to a decrease of the relative weight of testis and spleen, and to an increase in heart relative weight. In broilers fed diets containing JCM, the testis were atrophic, presenting reduced size of the seminiferous tubule, which were small and lined within active sertoli cells and rare spermatogonia. This study illustrates the negative impact of diets containing JCM on broiler performance and JCM pathological effects on several organs.
Navegar la universidad neoliberalizada: prácticas de adaptación y de queja de profesoras titulares

Este artículo tiene como objetivo presentar cómo profesoras titulares de la universidad pública más importante de Colombia navegan las carencias devenidas de la implementación de políticas neoliberales. Bajo un enfoque cualitativo, el trabajo de campo realizado incluye más de veinticuatro entrevistas, así como un acercamiento etnográfico con siete de las profesoras. Los resultados permiten señalar que, si bien hay una adaptación a las condiciones laborales imperantes, también hay quejas que se expresan mediante protestas individualizadas y de gestiones administrativas con las que modifican dichas situaciones, lo que devela que la sujeción a la gubernamentalidad neoliberal no es total.
LAME DE METIER A TISSER.

<P>L'invention concerne un cadre de lisses pour le déplacement oscillant des lisses à tisser dans un métier à tisser avec une barre de support et avec un rail de support de lisses s'étendant parallèlement à l'axe longitudinal de cette barre de support. <BR/> Selon l'invention, il comprend un dispositif de fixation (6) s'étendant à une distance fixe et parallèlement au rail de support de lisses (5) pour assurer une fixation en deux points des lisses à tisser (7) maintenues seulement par une de leurs extrémités sur le cadre pour permettre leur mouvement oscillant. <BR/> L'invention s'applique notamment à l'industrie textile.</P>
Detection of Simple and Pattern Regularity Violations Occurs at Different Levels of the Auditory Hierarchy

Auditory deviance detection in humans is indexed by the mismatch negativity (MMN), a component of the auditory evoked potential (AEP) of the electroencephalogram (EEG) occurring at a latency of 100-250 ms after stimulus onset. However, by using classic oddball paradigms, differential responses to regularity violations of simple auditory features have been found at the level of the middle latency response (MLR) of the AEP occurring within the first 50 ms after stimulus (deviation) onset. These findings suggest the existence of fast deviance detection mechanisms for simple feature changes, but it is not clear whether deviance detection among more complex acoustic regularities could be observed at such early latencies. To test this, we examined the pre-attentive processing of rare stimulus repetitions in a sequence of tones alternating in frequency in both long and middle latency ranges. Additionally, we introduced occasional changes in the interaural time difference (ITD), so that a simple-feature regularity could be examined in the same paradigm. MMN was obtained for both repetition and ITD deviants, occurring at 150 ms and 100 ms after stimulus onset respectively. At the level of the MLR, a difference was observed between standards and ITD deviants at the Na component (20-30 ms after stimulus onset), for 800 Hz tones, but not for repetition deviants. These findings suggest that detection mechanisms for deviants to simple regularities, but not to more complex regularities, are already activated in the MLR range, supporting the view that the auditory deviance detection system is organized in a hierarchical manner.
Neue Servicequalität im Hotel Karino Spa.

Ziel des Projekts ist es, die Qualität der im Karino Spa Hotel angebotenen Dienstleistungen durch den Einsatz moderner Ausrüstung mit der Unterstützung spezieller Informations- und Kommunikationstools in der gesamten Hoteleinrichtung zu verbessern. Zielgruppe sind alle Kunden, die Hoteldienstleistungen nutzen. Diese Investition wird aus drei Hauptstufen bestehen, die der Phase der Bereitstellung verbesserter Hoteldienstleistungen mit moderner Ausrüstung und Informations- und Kommunikationstechnologien im Karino Spa Hotel vorausgehen. Zu diesen Phasen gehören: (1) Ankauf neuer Anlagen – Klimaanlagen, die im Fitness- und Pubraum, im Büroteil, im Restaurantraum, im Obergeschoss/im Dachgeschoss in Hotelzimmern installiert werden. Kauf einer neuen Anlage – Ausrüstung für die Hotelküche. (2) Erwerb neuer Anlagegüter wie: Tablets, Tablet-Geräte, TV-Geräte. Kauf von immateriellen Vermögenswerten – Erwerb von Lizenzen für mobile Anwendungen für Gäste und Anwendung für Tablets und Fernseher in Hotelzimmern. (3) Erwerb neuer Anlagen – Ankauf von Türen zu Hotelzimmern (49 Stück) und Schlössern mit ble-Modul zum Öffnen per Smartphone. Kauf von immateriellen Vermögenswerten – eine Schnittstelle zum im Hotel verwendeten PMS-System für den Austausch von Daten über Buchungen und Berichte mit dem System, das Hoteldienstleistungen unterstützt. Projektdurchführungszeitraum vom 1.6.2020 bis 31.5.2021. Als Ergebnis des Projekts wird ein System zur Unterstützung der Hoteldienstleistungen implementiert.
Lyapunov exponents and rigidity phenomena in dynamical systems and mathematical physics

This fellowship builds on the success of the applicant’s PhD thesis, where he made breakthroughs in the study of the frequency of hyperbolic behavior, i.e. simplicity and non-vanishing of Lyapunov exponents in dynamical systems. The concept of Lyapunov exponent were introduced in the work of A. M. Lyapunov on the stability of the solutions of differential equations in 1892. The concept plays a central role in most areas of modern theory of dynamical systems, mathematical physics, differential geometry, among others. The problem of the frequency of hyperbolic behavior, in various settings, has been extensively investigated by many leading mathematicians. The main goal of this project is to study the Lyapunov exponents in the most general setting, and investigate its role in rigidity phenomena in dynamical systems. This project specifically aims at applying techniques from modern theories of complex analysis and complex geometry (field in which the supervisor is a world leading expert) to the study of Lyapunov exponents (the applicant’s area of expertise).

This proposal has four main objectives:
1 - Explain the frequency of the simplicity of Lyapunov spectrum for symplectic cocycles;
2 - Establish positivity of Lyapunov exponents for the general structure group;
3 - Understand the frequency of hyperbolic behavior for infinite dimensional ""symplectic"" cocycles;
4 - Employ new techniques from Lyapunov exponents to the rigidity conjectures, in particular, Katok-Spatzier types conjectures.
Experiencia de educación a distancia durante el confinamiento del COVID-19

El objetivo de esta investigación fue realizar un diagnóstico del desarrollo de la experiencia de la educación a distancia por la emergencia del COVID-19, en la Universidad Autónoma de Santo Domingo (UASD), Recintos San Francisco de Macorís, Santiago y Puerto Plata y en el Centro La Vega. La metodología implementada corresponde al enfoque cuantitativo, del tipo descriptivo, bibliográfico y de campo. Dentro de los resultados más importantes se pueden mencionar que el 62% de los estudiantes respondieron solo estar recibiendo docencia a distancia en algunas de las asignaturas seleccionadas en el semestre, 2020-1, mientras que el 16% señaló que están recibiendo docencia en todas las asignaturas. En conclusión, no se utiliza la plataforma de la universidad por el desconocimiento que poseen docentes y estudiantes en su implementación. Dentro de las recomendaciones, está la creación y fortalecimiento en todos los recintos y centros las unidades tecnológicas de apoyo a la docencia y a los estudiantes.
Contextual queries express mobile information needs

The users of mobile devices increasingly use networked services to address their information needs. Questions asked by mobile users are strongly influenced by contextual factors such as location, conversation and activity. We report on a diary study performed to better understand mobile information needs. We find that the type of questions recorded by participants varies across their locations, with differences between home, shopping and in-car contexts. These variations occur both in the query terms and in the form of desired answers. Both the location of queries and the participants' activities affected participants' questions. When information needs were affected by both location and activity, they tended to be strongly affected by both factors. The overall picture that emerges is one of multiple contextual influences interacting to shape mobile information needs. Mobile devices that attempt to adapt to users' context will need to account for a rich variety of situational factors.
Nondestructive Evaluation of Early Contact Fatigue Using Eddy Current Pulsed Thermography

Cyclic loading can lead to fatigue damage on the surface or subsurface of a gear tooth. In order to evaluate the contact fatigue damage, this paper applies eddy current pulsed thermography (ECPT) for fatigue damage characterization at different intervals of the loading cycle. The challenging task of fatigue evaluation is one of solving the qualitative microstructure state characterization before microcrack initiation. This paper proposes the thermooptical flow entropy tracking method to trace the heat flow and characterize the degree of fatigue damage while in this status no macrodefects appears using ECPT. In addition, the thermooptical flow is mathematically modeled to yield several desirable unique properties to evaluate minor variations in the microstructure of the material during the fatigue process. The nondestructive evaluation of fatigue damage with ECPT thermooptical flow is derived. The relationship between the entropy of thermooptical flow and the degree of contact fatigue at an early stage is established. The experimental study validates that the proposed method can detect and characterize the implicit damage and that the entropy of thermooptical flow is highly correlated with fatigue cycles which has the potential to evaluate the degree of fatigue damage.
FIRING MODULE

The invention relates to a firing module with a housing (1), mounted such as to rotate on a carrier construction (T), in which a heavy weapon (W) is mounted such as to pivot in elevation. The shells (4.11) stored vertically in the shell magazine (4.1) are supplied to the loading tray (5.1) of a shell ram by means of a shell transporter (6), which is arranged on the free end of a shell transfer arm (5). The shell transfer arm (5) can be pivoted from a raised position, in which the loading tray (5.1) is arranged running along the bore centre axis (R) of the weapon into a lowered position in which the shells from the shell transporter are introduced into the essentially vertical loading tray. The shell magazine and the shell transporter are both arranged in the housing in the region in front of the trunnions. At least one propellant magazine (7.1) is arranged in the housing in the region alongside or behind the trunnions. Propellant charges are introduced into the weapon (W) by means of a fully automatically operating propellant charge introduction device, which comprises a pivoting propellant charge introduction tray (8.11) with a propellant ram, in the region behind the weapon (W).
Horn and crescent. connections, mobility and exchange between the horn of africa and the middle east in the middle ages

This project offers the first comprehensive study of medieval connections between the Horn of Africa and the Middle East in both Christian and Islamic contexts. It pursues the hypothesis that mobility and exchange along trade and pilgrimage routes, on both sides of and across the Red Sea, were not only vectors for the spread of Islam but also factors of African Christianities’ resiliency and reconfiguration at the same time. Medieval connections of Ethiopian and Nubian Christianities with other Eastern Christian churches have longer been studied than has been the spread of Islam across the Red Sea or along the Nile valley which remains poorly known. These parallel connections within Christen- and Islamdom across the same area have never been studied jointly, nor have been Christian-Muslim relations on such a scale. The project ultimately aims to reconnect the Horn of Africa to the global history of the area by connecting disjoint fields of research.
It has the following objectives:
• Providing a comprehensive survey of connections between the Horn of Africa and the Middle East (places, items, contexts) supported by a database and a geographic information system
• Analyzing human mobility in the area within three critical configurations: pilgrimages (both Christian and Muslim), slave trade and slavery, metropolization (with the case study of Cairo)
• Exploring cultural transfer and dissemination in the area within and between Christen- and Islamdom through the circulation of books, models and narratives
• Evidencing regional connections and Christian-Muslim relations through archaeological survey at a very localised level: Nägaš (Ethiopia), a Muslim holy place in Christian environment related to the first exile (hijra) of Muḥammad’s companions
This project is groundbreaking in rallying around the PI historians working on the area’s various realms in their several written languages, in both Christian and Islamic contexts, from the Arab conquest until the Ottoman one.
The development of the economy and tourism in rural areas through the development of the horse

The overall objective of the project is to contribute to the sustainable development of cross-border territories of Tunisia and Italy through the development of economic sectors linked to breeding and training of the horse and the promotion of a joint offer of integrated Mediterranean tourism in rural areas. The specific objective is the development of synergies between economic sectors of breeding and training of the horse through the transfer of knowledge, best practices and new approaches and the creation of integrated equestrian itineraries  to contribute to the economic development of rural areas in Tunisia and Sicily .
An immunological hub of excellence in porto tailored to fulfil the era priorities

The mission of an ERA Chair in Immunology (ImmunoHUB) is to create a Platform of excellence in research and innovation at IBMC-i3S (Portugal). Cancer, infectious diseases, autoimmunity and neurodegenerative disorders are major problems affecting our society. These pathologies are studied at IBMC-i3S and result in in part from deregulated immune responses, which makes Immunology a core pillar in our institute. Moreover, the successful usage of immune checkpoint blockade therapies has revolutionized the treatment of cancer and highlights the importance of understanding how to harness the Immune system for future development of vaccines or therapeutics against these diseases. Despite the contributions of our research groups for the understanding of how immune responses are orchestrated in health and disease, the international visibility of IBMC-i3S as a research center of Excellence in Immunology remains modest.
The ImmunoHUB action will (1) project Immunology at IBMC-i3S towards the forefront of basic and translational biomedical research, (2) provide knowledge of fundamental and economical value,  (3) promote the finest academic practices to train the next generation of Immunologists and (4) widen public awareness for the importance of Immunology. Taking advantage of our high-quality scientific, technological, administrative and governance structures, we have set a comprehensive work plan to facilitate the integration and sustainability of the ERA Chair team and the implementation of the ImmunoHUB project. Our proposal is aligned with the existing scientific policy in Portugal and with the Societal Challenges and the ERA priorities identified by the European Commission under the H2020 program. Together, these synergistic actions will play a pivotal role to equip Portugal with the cornerstone infrastructures and human resources of the highest level to reach scientific excellence in Biomedical Research across Europe.