SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Efficient mixing method at the microscale for time-resolved serial femtosecond crystallography

X-MIXING is an interdisciplinary project aimed at conceiving an efficient mixing method at the microscale suitable for triggering not-light sensitive biochemical reactions in the application of Time-Resolved Serial Femtosecond Crystallography. Nowadays, the temporal resolution of this type of dynamic structural biology analysis with X-ray Free-Electron Lasers is limited by the minimum mixing time that current methods can produce. As it is shown in a proof-of-concept, an exciting combination of electrohydrodynamic fields and momentum transfer lead to a significant variation of the spatiotemporal scales within the convection-diffusion mechanism. So, this configuration can potentially generate mixing from 100 to 1000 faster than current means do.  Besides, its versatility would enable not only to reduce the mixing time substantially, but also to induce jumps in PH and temperature that would additionally open horizons concerning new types of triggering reactions in the field. These critical features have the potential to become this original configuration in a key to take full advantage of the recent significant investment, over 1,22 billion euro (2005 value), paid by European Union and partners for the construction of the European XFEL (Germany), whose user operation started in September 2017. To explore and elucidate the underlying physical limits of the proposed method, the research methodology of this project will embrace different approaches such as micro-PIV experiments, numerical simulations, and scaling analysis.
APPARATUS AND PROCESS FOR REMOVING SOLID PARTICLES FROM GASES

An apparatus for removing solid particles from a gas containing solid particles, comprising a filter container, a plate provided with openings across the filter container such that the plate divides the container in an upper and lower space and a number of filter elements extending under the openings, wherein a plurality of outlet conduits are present which are in fluid communication with one or more filter elements, said outlet conduits having an outlet opening which is in fluid communication with the upper space and wherein around said outlet conduit a cap is present, which cap is provided with means for supplying a backflushing fluid for removing solid particles from said filter elements and wherein the volume between the cap and the outlet conduit is sufficiently large to ensure that predominately only the clean gas between cap and outlet conduit is entrained by the backflushing fluid into the filter element when removing solid particles.
European support to social innovation

The four Regional Development Agencies, ERVET, ADA, KAINUUN ETU, IVACE operating in the North and in the South European Regions (Italy, Turkey, Finland, Spain), dealing with innovation support programmes, implementation of Structural Funds Regional Operative Programmes (ROP ESF, ERDF 2020) and experienced in social innovation policies and programs want to deepen their knowledge and find joint solutions to challenges hindering the development of social economy. Thus, they want to promote new approaches able to overcome a fragmented approach to policies supporting  social economy and the  innovation and competitiveness of social enterprises. A new policy mix, taking into consideration social, economic and environmental aspects (Agenda 2030), would be able to overcome “silos policies” and to create a favorable ecosystem for social enterprises. They will work together with regional public and private social economy stakeholders to analyze beneficiaries’ needs and promote new policies and actions. Already existing approaches and best practices will be shared in a mutual learning process among Regional Development Agencies, and related regions, that will be enlarged through EURADA and ERRIN networks for more effective and targeted regional and European  innovation programs for social enterprises. Moreover, partners, accordingly with INNOSUP general scope, choose to focus on social innovation as it is “required at the interface between public services and private enterprises” with a view to jointly learn and discuss about public and private partnership and co-design approach
Assessing LakeSmart, a community-based lake protection program

Anthropogenic impacts, particularly shoreline development and related nutrient runoff, threaten Maine lakes. The LakeSmart program was created in response to these threats to promote the use of lake-friendly landscaping practices. We used 237 surveys and 8 stakeholder interviews to investigate motivations that drive conservation behavior among lakeshore residents, to explore the effectiveness of criteria used for LakeSmart evaluations and to identify potential areas for improvement of its structural design and marketing strategies. LakeSmart participants were more likely than non-participants to recognize the threat of declining water quality, to adopt or enhance existing lake-friendly landscaping best management practices, and to help foster a strong sense of community. We conclude that the LakeSmart program could be strengthened with enhanced training for inspectors through increased “job-shadowing” opportunities with experienced inspectors, expanded mentoring for owners whose properties do not pass the initial LakeSmart evaluation, and by eliminating ambiguous wording in the property evaluation form. Partnerships with member-rich groups and identifying ways to reduce costs of recommended mitigation actions could increase program participation. The defined parameters of the property evaluation, along with recommendations to strengthen the evaluation process, can result in greater citizen participation and ultimately improved lake ecosystem health measured by fewer algal blooms and greater water clarity. LakeSmart could serve as a model for other conservation programs attempting to transform knowledge to action.
Camellia sinensis (green tea) extract attenuate acrylamide induced testicular damage in albino rats

Acrylamide is a proved toxin for testicular function, found in food when heated for long period of time. Green tea (Camellia sinensis) is a potent antioxidant; the aim of this study was to investigate the protective effect of green tea extract against the toxic effects of acrylamide in rat testes.acrylamide was administered orally to rats in different doses and also the extract of green tea was administered orally to different groups of animals in combination with the acrylamide. The weight of animals, testosterone hormone level and histopathological effect upon testicles were evaluated.Testosterone hormone level in serum, and histopathological findings were significantly improved with the co-administration of green tea extract with the acrylamide. Green tea extract reversed all the toxic effects of acrylamide even in high dose for long period (90 days).Green tea extract is a potent antioxidant antidote for the acrylamide toxic effects upon testicular function.
A new design of multi-mesh survey gillnets to sample fish community in the Adriatic Sea

Three types of multi-mesh benthic survey gillnets were tested for their performance in the uniform muddy bottom habitat of the Bay of Piran. We describe the compared methods, present their positive and negative aspects and suggest a sampling design that could be used with different research goals. The research sampling was performed in winter in the years from 2010 to 2012. The sampling site is situated close to a sea bass rearing fish farm in the Northern Adriatic Sea. With the Nordic 1.5 type nets 5 species were detected compared to the 23 and 20 species detected with the Adriatic 2.5 and 5.0 nets. In the Nordic 1.5 type nets only demersal species were caught and even for those a much greater sampling effort would be required to reach a representative sample. On the other hand, both the Adriatic type nets also caught benthopelagic and pelagic species, and a correlation between net height and size of fish in these two nets was detected. While both the Adriatic type nets proved successful in achieving a representative sample of fish assemblage, the Adriatic 2.5 nets performed better in terms of CPUE and as such also reached a better cost-benefit ratio. ISSN: 0001-5113 - AADRAY ACTA ADRIAT., 54(2): 169 - 182, 2013
Beasts to craft: biocodicology as a new approach to the study of parchment manuscripts

The intention of Beasts to Craft (B2C) is to document the biological and craft records in parchment in order to reveal the entangled histories of animal improvement and parchment production in Europe from 500-1900 AD. 

B2C will lay the foundations for a new approach to the the study of parchment manuscripts —biocodicology— which draws evidence from the overlooked first stages in production, the raising of livestock and the preparation of the skins. 

1. Parchment is an extraordinary but overlooked high resolution zooarchaeological record and a molecular archive. Livestock genetics is revealing breed diversity and markers of character traits such as fleece quality. B2C will exploit this new-found knowledge, using progressively older dated archival (sheep) parchments to study the history of improvement 1300 - 1900. Visual examination of the skins will search for direct evidence of disease and fleece quality. 

2. Craft skills can be read from parchment and, when combined with chemical data and comparison with modern analogues, will produce the first European wide record of the craft from 500-1900. The size and scope of this the parchment archive means it is one of the largest and most highly resolved records of a specialist medieval craft. We will explore how these skills develop and when and where regional patterns appear and decline. 

These two remarkable records requires a large interdisciplinary team. However biocodicology draws from and informs upon a wide and diverse spectrum of existing scholarship in conservation, the arts and sciences. A third strand of the project will (i) furnish manuscript scholars with some of the information available to the scribe at time of production (ii) inform and shape attitudes to parchment conservation (iii) provide high resolution biological data on animal management, movement and health and (iv) explore methods to link datasets and promote data reuse.
PLASTIC PROJECTILE FOR PRACTICE SHOOTING

A soft plastic or elastomeric projectile for practice shooting, comprising a front portion (1a) with a sealing lip, two or more peripheral guide rings (4a and 4b) and a central rear recess (5).
Sensitivity and False Alarm Rate of a Fall Sensor in Long-Term Fall Detection in the Elderly

&lt;b&gt;&lt;i&gt;Background:&lt;/i&gt;&lt;/b&gt; About a third of home-dwelling older people fall each year, and institutionalized older people even report a two- or threefold higher rate for falling. Automatic fall detection systems have been developed to support the independent and secure living of the elderly. Even though good fall detection sensitivity and specificity in laboratory settings have been reported, knowledge about the sensitivity and specificity of these systems in real-life conditions is still lacking. &lt;b&gt;&lt;i&gt;Objective:&lt;/i&gt;&lt;/b&gt; The aim of this study was to evaluate the long-term fall detection sensitivity and false alarm rate of a fall detection prototype in real-life use. &lt;b&gt;&lt;i&gt;Methods:&lt;/i&gt;&lt;/b&gt; A total of 15,500 h of real-life data from 16 older people, including both fallers and nonfallers, were monitored using an accelerometry-based sensor system with an implemented fall detection algorithm. &lt;b&gt;&lt;i&gt;Results:&lt;/i&gt;&lt;/b&gt; The fall detection system detected 12 out of 15 real-life falls, having a sensitivity of 80.0%, with a false alarm rate of 0.049 alarms per usage hour with the implemented real-time system. With minor modification of data analysis the false alarm rate was reduced to 0.025 false alarms per hour, equating to 1 false fall alarm per 40 usage hours. &lt;b&gt;&lt;i&gt;Conclusion:&lt;/i&gt;&lt;/b&gt; These data suggest that automatic accelerometric fall detection systems might offer a tool for improving safety among older people.
Preparation of spherical caged superparamagnetic nanocomposites with completed inorganic shell via a modified miniemulsion technology

Abstract A one-pot facile method is developed to synthesize spherical caged polystyrene/Fe3O4@SiO2 nanocomposites (SCNs) microspheres with intact inorganic shells in a high yield via a combining process of miniemulsion polymerization and sol–gel reaction. It is revealed that St to TEOS ratio, the controlled hydrolysis and condensation rate of TEOS both play important roles in the structure formation. Control experiments are performed to understand the possible mechanism. With iron oxide nanoparticles as inorganic seeds, this one-pot synthetic method shows apparent advantage over multi-step layer-by-layer coating and selective etching regarding the simpleness and efficiency. Regular hollow magnetic mesoporous silica composites could easily be prepared using the caged magnetic microspheres as the template. The novel and facile method for preparing the magnetic composites with intrinsic space and intact shell could promote the development of drug carrier or photocatalysis system.
Association Scheme with Traffic Control for IEEE 802.11 Wireless LANs

In wireless LANs, wireless clients are associated with one of access points (APs) to obtain network connectivity, and the AP performs network traffic relay between the wired infrastructure and wireless clients. If a client with a low transmission rate is associated with an AP, the throughput performance of all the clients that are associated with the AP is significantly degraded because of the long channel usage time of the low-rate client. Therefore, it is important to select an appropriate AP when a new client joins the wireless LAN to prevent the performance degradation. In this paper, we propose a traffic control that determines the feasible data traffic from an AP to the clients on the basis of the trade-off relationship between the equal-throughput and equal-airtime traffic allocation policies. We then propose a network-wide association algorithm that allows a client to be associated with the AP that can provide the highest throughput improvement. Simulation results indicate that the proposed algorithm achieves the better aggregate throughput and throughput fairness performances in IEEE 802.11 WLANs.
JPTT20-COVID19-LX-CONFIG

Configurador on-line de placa de instrumentos em aeronaves — Atividade c) Fazer ferramentas digitais para configurar a solução de produtos selecionados por um potencial cliente em pelo menos uma língua estrangeira, incluindo tradução
Evaluation of dyadic psychoeducational interventions for people with advanced cancer and their informal caregivers (diadic): an international randomized controlled trial

Background: Advanced cancer affects millions of Europeans each year. The provision of adequate and cost-effective psychosocial and educational support for both patients and their frequently overburdened family caregivers is highly relevant from an economic, a healthcare and a prevention perspective.  Aims: The DIAdIC project is an interdisciplinary, cross-national project to evaluate the effectiveness and cost-effectiveness of two psycho-educational dyadic interventions, i.e. interventions that target the patient and family caregiver together. One intervention is a web-based e-health intervention, one is nurse-led face-to-face intervention. Secondary aims are to assess the interventions' effects on vulnerable subgroups (e.g. people with a lower socioeconomic position), their effectiveness in different healthcare systems, and their suitability as perceived by end-users.   Concept and methods: The two interventions are tailored to dyads' needs and have 5 core components: (1) supporting family involvement, (2) reducing hopelessness, (3) increasing coping effectiveness, (4) reducing uncertainty and (5) teaching symptom management. They are based on existing interventions, developed in the USA, that have been shown to improve quality of life of both patient and family caregiver. The effectiveness of each of the interventions (compared to care as usual) will be assessed by way of an international randomized controlled trial in people with advanced cancer and their primary informal carers. The project includes a full health-economic evaluation and a thorough process evaluation.   Impact: The project advances the state of the art in several ways, e.g. by providing innovative healthcare interventions (including a eHealth solution) that embrace the philosophy and principles of early palliative care. The interventions will be suitable for implementation across diverse healthcare systems. Public involvement methods ensure the input of stakeholders throughout the project.
Reversible solid–gas and solid–solid transformation of lead(II)–phenylalanine coordination polymers

Abstract A reversible crystal to crystal structural transformation of lead(II) complex; [Pb(OH2)2(Phe)2(NO3)]n[NO3] (1), (Phe:L-phenylalanine), to coordination polymer 2D [Pb(phe)2]n (2); has been observed upon solid–gas and solid–solid reactions of compound 1 to compound 2 and then 2 to 1. A lead(II) supramolecular (1), polymerizes on grinding the solid with 1 mmol NaOH and also with NH3 vapors to form the 2D coordination polymer (2). Solid–gas reaction has been verified by PXRD and IR spectroscopy. Pb3O4 and mixture phase of PbO nanoparticles were obtained by thermal decomposition of compounds 1 and 2 by direct calcinations at 400 °C for 4 h. These nanoparticles were characterized by powder X-ray diffraction (PXRD) and scanning electron microscopy (SEM).
Promotion of the Mobility of Youth and Young Adults in rural areas through better access to European and national passenger transport networks

YOUMOBIL aims at enhancing the passenger transport system for young people living in rural areas and their access to the European and national transport networks. Poor mobility options other than the own car is among the most frequent reasons why young people choose to leave their native rural area and to migrate to larger cities or even beyond, intensifying the demographic change troubling most rural areas in Central Europe. A number of tools including shared mobility and demand-oriented flexible collective transport services have emerged across Europe but only few have been introduced in rural areas of Central Europe. This led to a lack of knowledge among the programme area&#39;s transport stakeholders. Moreover, public transport and related infrastructures suffer from a rather poor image among Central European youth. YOUMOBIL partners therefore network with rural areas&#39; local youth in piloting demand-driven novel service features, exploit the potentials of transport management through interfaces for mobile devices, and to explore how youth initiatives can revitalise disused rail infrastructure to enhance the attractiveness and image of public transport. Five technology-driven pilots will demonstrate the use of modern ICT solutions for a smart youth-orientied transport in rural areas while one investment showcases the role of young people to revitalise rail infrastructure. Further investments are prepared by YOUMOBIL.
 
Lessons learnt and knowledge from existing good practices will be shared among transport stakeholders in two summer schools and disseminated in the form of a tool-box that includes details about the financial feasibility of necessary investments complemented by policy recommendations. These outputs address public transport managers from rural areas of CE. Accompanying communication activities include three annual campaigns sending groups of local youth by Interrail to all partner territories and producing daily social media footage.
Conditions and duration of high temperature metamorphism in large hot orogens assessed through petrochronology : insights from grenville tectonics

Deciphering duration and conditions of metamorphism in orogenic systems is crucial to understand large-scale tectonic processes. In the last decades, the development of thermodynamic modeling and instrumental advances in elemental and isotopic analysis have open new avenues to unravel the Pressure-Temperature-time paths of rocks, to assess the rates and duration of large-scale orogenic processes. However, orogenic roots in Large Hot Orogens (LHOs) that can attain and maintain temperatures higher than 800°C over several tens of million years still challenge our ability to decode the timing of events, and our understanding of tectonic processes and crustal evolution.
CHRONOTEC proposes an innovative multi-approach strategy using state-of-the-art instrumentation, to link the chronometers garnet and zircon through their isotopic (U-Pb in zircon; Lu-Hf and Sm-Nd in garnet, O in garnet and zircon) and elemental (trace element) record, combined to a detailed petrological investigation, including phase diagram modeling. This approach will be systematically used on selected mafic granulites from distinct crustal levels (mid and high pressure) of the Central Grenville Province in Canada, one of the first LHOs on Earth. CHRONOTEC will bring a complete portfolio of new fundamental results from natural samples to assess the link between zircon and garnet in high-T mafic rocks. Integration of the results will provide an unparalleled framework to assess the metamorphic evolution of the central Grenville province, and by comparison to other LHOs, will refine our understanding of large-scale high-T orogenic processes.
METHOD AND COMPOSITION FOR TREATING TUMORS HAVING HIGH TYROSINASE ACTIVITY

Tumor cells which have beta -glucuronidase and tyrosinase activity are selectively treated by administration of a conjugate of a cytotoxic compound which is a substrate for tyrosinase and glucuronic acid or a pharmaceutically acceptable salt or ester thereof, particularly the triacetylated form of glucuronic acid. Among the cytotoxic phenolic compounds which are substrates for tyrosinase which can be used are tyrosine, 4-hydroxyanisole, butylated hydroxyanisole, L-3,4-dihydroxyphenylalanine, dopamine (3,4-dihydroxyphenethylamine), terbutylcatechol, hydroquinone, resorcinol, 6-hydroxydopa (3,4,6-trihydeoxyphenylalanine) and methyl gallate.
STRENGTHENING CROSS-BORDER GOVERNANCE THROUGH DEVELOPMENT OF SKILLS AND LOCAL GOVERNMENT MODELS

The GovernaTIVA project will involve a highly interconnected geographical area in terms of history, culture and economy: the Varese area and the Canton Ticino. The current context highlights some critical aspects: limited mutual knowledge between public and private actors on both sides of the border, the predominance of small and fragmented local administrations, a lack of full assimilation of governance competences by political decision makers and public personnel. The project aims to increase the capacity of inter-institutional and territorial governance of the Municipalities as an indispensable condition for fostering cooperation actions and benefit the economic and social development of local communities.