SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Low-Emission adaptive last mile logistics supporting 'on demand economy' through digital twins

LEAD will create Digital Twins of urban logistics networks in six cities, to support experimentation and decision making with on-demand logistics operations in a public-private urban setting. Innovative solutions for city logistics will be represented by a set of value case scenarios, that address the requirements of the on-demand economy while aligning competing interests and creating value for all different stakeholders. Each value case will combine a number of measures (LEAD Strategies):
a) innovative business models,
b) agile urban freight storage and last-mile distribution schemes,
c) low emission, automated, electric or hybrid delivery vehicles, and
d) smart logistics solutions.
Scenarios will incorporate opportunities for shared, connected and low-emission logistics operations by considering four innovation drivers: Sustainability - Zero Emission Logistics, the Sharing Economy, Technology Advancements and the emerging Physical Internet (PI) paradigm.
Cost, environmental and operational efficiencies for value cases will be measured in 6 Living Labs (Madrid, The Hague, Budapest, Lyon, Oslo, Porto). Evidence-proven value cases and associated logistics solutions will be delivered in the form of exploitable Digital Twins (TRL-7), incorporating the models that support adaptation to different contexts and that provide incentives for PPPs. The long-term vision of LEAD is to design an Open PI-inspired framework for Smart City Logistics that incorporates the Digital Twins created in the project, thus setting the foundations for the development of large-scale city Digital Twins.
The LEAD consortium comprises 22 partners, all of whom are involved in the Living Labs, supported by 5 international partners for knowledge transfer. This incentivises the co-creation of solutions by city authorities, logistics industry leaders, start-ups and research experts in freight modelling, complex simulation and logistics optimisation.
Cox‐2 Regulation Differs Between Sexes in the Secondary Inflammatory Response Following Experimental Penetrating Focal Brain Injury in Rats

Traumatic brain injury (TBI) is followed by secondary neuronal degeneration, largely dependent on an inflammatory response. This response is probably gender specific, since females are generally better protected than males in animal models and human epidemiological studies of TBI. The reasons are not fully known. We examined aspects of the inflammatory response following experimental TBI in male and female rats to explore possible gender differences. A penetrating brain injury model was used to produce focal TBI in male (n=10) and female (n=10) rats. After 24 h and 72 h the brains were removed and subjected to immunohistochemical analyses and in situ hybridization. Cox‐2 mRNA was elevated in the perilesional area compared to the un‐injured contralateral side, and significantly higher in males compared to females at 24 h and 72 h (p<0.05). iNOS mRNA and protein expression, GFAP, osteopontin, 3‐nitrotyrosine and Fluoro Jade positive cells were upregulated in the perilesional area at 24 h with no difference between sexes. Our findings showed a gender difference in posttraumatic Cox‐2 levels in Sprague‐Dawly rats. It is possible that the sex specific trait of the secondary inflammatory response may be connected to prostaglandin regulation rather than oxidative stress also in clinical contexts. The difference did, however, not correlate with altered neuronal death at 24 h. Astrogliosis and microgliosis did not differ between sexes. This heterogeneity comprises a sex dependent quality. The identification of gender specific post‐traumatic processes demonstrates a gender‐specific metabolic quality, which may partially explain variances in outcome after TBI.
Voltammetric Analysis of Herbicide Picloram on the Silver Solid Amalgam Electrode

ABSTRACTA silver solid amalgam electrode was employed for the first time for the determination of the pyridine herbicide picloram. The voltammetric behavior of this herbicide was studied using cyclic, direct current, and differential pulse voltammetry on the mercury meniscus modified silver solid amalgam electrode. All results were compared with those achieved on the classic hanging mercury drop electrode. One reduction signal, which was suitable for analytical purposes, was recorded on the amalgam electrode after addition of picloram. The current response of the herbicide increased linearly in the concentration range from 1 × 10−7 to 8 × 10−5 moles per liter, and a limit of detection of 8.78 × 10−8 moles per liter was obtained using differential pulse voltammetry under the optimized conditions. The selectivity and applicability of the voltammetric technique was verified by an interference study and analysis of fortified environmental samples with excellent recoveries: 100.0%(tap water), 100.5% (dam water...
One-component novel allyl–maleimide Alder ene resins: synthesis, curing, and thermal properties

Novolac resins, bearing both allyl and maleimide groups in varying proportions and capable of self-curing via Alder ene reaction, were synthesized by anchoring maleimidobenzoyl groups onto allyl novolac resins. These systems are capable of self-curing at moderate temperature by undergoing two-step cure reaction, i.e. ene reaction (~60 °C) followed by Diels–Alder reaction (~180 °C) to form thermal stable resins. Anchoring of the allyl and the maleimide groups in the same molecule decreases the cure activation energy tremendously due to increased proximity of reactive species and favorable activation entropy factors. The increase in activation energy with conversion implied that the reaction migrates from chemically controlled zone to diffusion-controlled zone beyond ~50% conversions. The resins showed increasing thermal stability with enhanced maleimide content.
Extrapolative prediction using physically-based QSAR

Surflex-QMOD integrates chemical structure and activity data to produce physically-realistic models for binding affinity prediction . Here, we apply QMOD to a 3D-QSAR benchmark dataset and show broad applicability to a diverse set of targets. Testing new ligands within the QMOD model employs automated flexible molecular alignment, with the model itself defining the optimal pose for each ligand. QMOD performance was compared to that of four approaches that depended on manual alignments (CoMFA, two variations of CoMSIA, and CMF). QMOD showed comparable performance to the other methods on a challenging, but structurally limited, test set. The QMOD models were also applied to test a large and structurally diverse dataset of ligands from ChEMBL, nearly all of which were synthesized years after those used for model construction. Extrapolation across diverse chemical structures was possible because the method addresses the ligand pose problem and provides structural and geometric means to quantitatively identify ligands within a model's applicability domain. Predictions for such ligands for the four tested targets were highly statistically significant based on rank correlation. Those molecules predicted to be highly active (pK(i) ≥ 7.5) had a mean experimental pK(i) of 7.5, with potent and structurally novel ligands being identified by QMOD for each target.
Molecularly imprinted photocatalytic light-driven micro/nanomotors for selective degradation and detection of pollutants in water and food

In recent years, the use of toxic pesticides in agriculture has been intensified to fulfill the increasing demand for food, at the expense of a heavily polluted environment. Growing of food using polluted water causes serious risks for human health. Therefore, Europe has introduced increasingly stringent regulations on food production quality, which require a sensitive and selective screening system that can detect pesticides in water and food. Micro/nanomotors, combining the enhanced physicochemical properties of micro/nanoscale materials with their autonomous motion capability, have demonstrated a great potential for the fast degradation of pollutants into electrochemically detectable products. Still, there is no control on their degradation ability, as they ""shoot and degrade"" any pollutant on their path, leading to a non-selective detection. Moreover, the motion is generally achieved by using toxic fuels or through the decomposition of motors themselves, limiting their practical applications. 
The present MSCA IF project ""MIPhmotors"" aims to selectively and sensitively detect toxic pesticides in water and food by employing for the first time the molecular imprinting technique for the preparation of photocatalytic micro/nanomotors with various sizes and shapes. This innovative class of motors will be able to exploit a renewable and abundant resource as light to move and, at the same time, selectively photodegrade the imprinted pesticide via the specific recognition sites created by molecular imprinting. Then, the electro-active degradation product will be detected by electrochemical measurements using commercial screen-printed electrodes.
The proposed research activity can be extended for the detection of other pollutants, and will open new opportunities in the field of micro/nanomotors and in their application for water purification, sensing and biomedicine.
PROCESS FOR THE TREATMENT OF CELLULOSE FIBERS

A method for the treatment of cellulose fibers is provided, the method comprising the steps of - impregnation of cellulose fibers with a solution comprising a tetraalkoxysilane and a solvent selected from monofunctional alcohols R4OH; - squeezing out the solution from in between the cellulose fiber walls; wherein the weight ratio of the solution to the dry weight of the cellulose fibers after the step of squeezing is lower than 2.
Trilateral EmpoweRment for Change 4.0

Puglia, Albania and Montenegro are connected by good economic relations, which are strengthening with the process of adjustment towards European standards that Albania and Montenegro are going through to entry the EU. The Region today faces the innovation challenge, through the smart factory model, equipped with self-check devices in the lines of production, escalation of companies’ digital processes and high cross-border connectivity.
inTERaCt 

4.0 will promote the development of this growth model, through four key actions:


1. Analysis, based on research and methodological surveys, of the needs of enterprises in the handcrafted production sector;


2. Definition of the Mediterranean Innovation Hub (MIH), an instrument shared by the three countries, to promote and support  broad approach to innovation. At the operational level, the MIH aims at: the construction of an environment that gathers industrial associations, research centres and enterprises around a smart model; develop an office that provides technical support on research and innovation and the economic measures to support them; development of a “Smart Showcase”, a training experiential workshop to share digital solutions for company processes.


3.  Establishment of a system economically viable over time, to train and update the human capital that will support the enterprises’ upgrade, in terms of organization and production;


4. Creation of an ICT & Skills Cluster Platform and Technological Services, to share and benefit from sharing of company skills, guidelines and policy documents for the transformation of processes inside the handcrafted production sector.
TRIAXIAL BRAID FABRIC ARCHITECTURES FOR IMPROVED SOFT BODY ARMOR BALLISTIC IMPACT PERFORMANCE

A fabric comprising a first plurality of yarns, a second plurality of yarns and a third plurality of yarns wherein the first, second and third pluralities of yarns have a yarn orientation that is different from each other. The third plurality of yarns is oriented in an axial direction. The second plurality of yarns is interwoven with the first plurality of yarns. The third plurality of yarns have no crimp. The yarns of the second plurality of yarns have an average linear density greater than or equal to the average linear density of the yarns of the first plurality of yarns and the yarns of the third plurality of yarns have an average linear density greater than the average linear density of the yarns of the second plurality of yarns and less than three times the average linear density of the yarns of the first plurality of yarns.
All In The Timing

This article discusses the primary concerns of rail passengers in the United Kingdom. Passenger Focus, an organization that was established in 2005 to represent British rail passengers, gathers much of its information through an annual National Passenger Survey and uses its findings to highlight passenger concerns. The latest research by Passenger Focus shows that the most critical concern for passengers is that their trains arrive on time. Passenger Focus has determined that although most trains arrive at their final destination on time, the trains are often late to arrive at intermediate stations. Trains that are just one minute late decrease customer satisfaction. Passengers are also concerned about fares, which rose an average of 5.8% last year. Although passengers have a negative opinion of ticket barriers that have been installed in many stations, Passenger Focus sees the barriers as a necessary feature for ensuring security and revenue. Another common passenger concern is the lack of information provided during disruptions. Passenger Focus hopes that train operating companies will continue to work hard to meet these customer priorities.
SAFETY BATHING APPARATUS

A safety bathing apparatus (10) including a flexible waterspout, having a flexible skin (11) with an inlet (17) and an outlet (18), a flexible conduit (14) disposed within the flexible skin having a first end (32) in fluid communication with the inlet of the flexible skin and a second end (33) in fluid communication with the outlet of the flexible skin, a buffer (12), disposed within the flexible skin and substantially encasing the conduit, and at least one flexible valve handle (20).
Restoration of productive capacity João Filipe Antunes Paiva

It consists of the purchase of basic equipment, the construction activity, for the replenishment of the productive capacity, which he had before the fires, where the promoter had very large losses.
The impact of credit supply on sales growth: Swedish evidence

Purpose – The purpose of this paper is to empirically investigate the impact of credit supply on sales growth among small- and medium-sized enterprises (SMEs). Design/methodology/approach – The three-stage least square (3SLS) method was used to analyse a cross-sectional panel data set covering 13,548 Swedish SMEs across four industry sectors from 2009 to 2012. Findings – The study provides empirical evidence that trade credit in terms of accounts receivable significantly and positively affects sales growth, indicating that SMEs investing more in accounts receivable are more likely to achieve growth. Furthermore, lagged sales growth and firm size are positively, while firm age is negatively, related to growth. Practical implications – Managers can increase firm growth by efficiently managing the supply of credit to their customers, especially liquidity-constrained firms, thereby increasing sales growth. Originality/value – To the authors’ best knowledge, this is one of the first empirical studies of the impact of credit supply in terms of accounts receivable on sales growth. The study applies the 3SLS method to a comprehensive cross-sectoral sample.
Thermosensitive Gel Containing Cellulose Acetate Phthalate-Efavirenz Combination Nanoparticles for Prevention of HIV-1 Infection

The objective of this investigation was to develop and evaluate a nano-microbicide containing a combination of cellulose acetate phthalate (HIV-1 entry inhibitor) and efavirenz (anti-HIV agent) for HIV prophylaxis. Cellulose acetate phthalate-efavirenz combination nanoparticles (CAP-EFV-NPs) were fabricated by the nanoprecipitation method and were characterized for particle size, zeta potential and encapsulation efficiency of efavirenz. CAP-EFV-NPs were incorporated into a thermosensitive gel (CAP-EFV-NP-Gel). CAP-EFV-NPs, CAP-EFV-NP-Gel and efavirenz solution were evaluated for cytotoxicity to HeLa cells and for in vitro short-term (1-day) and long-term (3-day) prophylaxis against HIV-1 infection in TZM-bl cells. CAP-EFV-NPs had size < 100 nm, negative surface charge and encapsulation efficiency of efavirenz was > 98%. CAP-EFV-NPs and CAP-EFV-NP-Gel were significantly less toxic (P < 0.01) to HeLa cells as compared to efavirenz solution. CAP-EFV-NPs showed significantly higher prophylactic activity (P < 0.01) against HIV-1 infection to TZM-bl cells as compared to efavirenz solution and blank CAP nanoparticles. CAP-EFV-NP-Gel can be a promising nano-microbicide for long-term HIV prophylaxis.
Review of: Paolo Pellegrini, Dante Alighieri: Una vita, Giulio Einaudi, Torino 2021 (Piccola Biblioteca Einaudi, nuova serie, 747: Saggistica letteraria e linguistica), XXII + 252 pp., ISBN 9788806247218.

Review of:&#x0D; Paolo Pellegrini, Dante Alighieri: Una vita, Giulio Einaudi, Torino 2021 (Piccola Biblioteca Einaudi, nuova serie, 747: Saggistica letteraria e linguistica), XXII + 252 pp., ISBN 9788806247218.
Do gut microbial communities differ in pediatric IBS and health?

Human gastrointestinal microbial communities are recognized as important determinants of the host health and disease status. We have recently examined the distal gut microbiota of two groups of children: healthy adolescents and those diagnosed with diarrhea-predominant irritable bowel syndrome (IBS). We have revealed the common core of phylotypes shared among all children, identified genera differentially abundant between two groups and surveyed possible relationships among intestinal microbial genera and phylotypes. In this article we explored the use of supervised and unsupervised ordination and classification methods to separate and classify child fecal samples based on their quantitative microbial profile. We observed sample separation according to the participant health status, and this separation could often be attributed to the abundance levels of several specific microbial genera. We also extended our original correlation network analysis of the relative abundances of bacterial genera across samples and determined possible association networks separately for healthy and IBS groups. Interestingly, the number of significant genus abundance associations was drastically lower among the IBS samples, which can potentially be attributed to the existence of multiple routes to microbiota disbalance in IBS or to the loss of microbial interactions during IBS development.
AN ELECTROSTATIC INTERMINGLING DEVICE AND A PROCESS FOR INTERMINGLING FILAMENTS

The present disclosure relates to an electrostatic intermingling device and a process for intermingling filaments. The filaments are intermingled to produce a yarn. The electrostatic intermingling device comprises a funnel, an expansion tube, a plurality of slits, a plurality of electrodes, and an electrically grounded disc. The plurality of slits are configured on the periphery of the expansion tube to receive a plurality of electrodes. The funnel is adapted to statically charge the filaments passing therethrough. The polarity of the plurality of electrodes is selectively altered to modify the spatial configuration of the statically charged filaments, so as to intermingle the statically charged filaments and obtain intermingled charged filaments. The electrically grounded disc is adapted to receive and neutralize the intermingled charged filaments. The electrostatic intermingling device and the process of the present disclosure are economical.
High-Precision global analysis of color-free lhc processes at small recoil

The Large Hadron Collider (LHC) at CERN collides protons at the highest energies. With the large datasets from Run 2 and the further increase expected from Run 3, the precision of LHC measurements will significantly improve over the next years. Color-free processes (for which the final state of the hard interaction is color neutral) are of central importance to several high-priority areas of the LHC precision physics program. Prominent examples are measurements of the W-boson mass, of the couplings of the Higgs boson, and searches for the elusive dark matter particles.

The key innovation of COLORFREE will be to combine many different color-free processes in a new type of global analysis in which the dominant theory uncertainties are either eliminated or constrained by the data itself, thereby improving the theoretical precision up to an order of magnitude to the 1-2% level. In doing so, COLORFREE will unlock the full potential of existing and future precision measurements of color-free processes.

This will be achieved 1) by exploiting and further developing a groundbreaking new method to reliably quantify perturbative theory uncertainties and their correlations, which was recently developed by the PI, and 2) by developing innovative new effective-field theory methods to account for all effects that are relevant at this precision but have been neglected so far.

Important outcomes of COLORFREE will be:

1) Determinations of fundamental parameters at the highest possible precision, and stringent tests for possible effects beyond the Standard Model.

2) A new type of precision theory predictions with built-in uncertainties and correlations, which will solve a long-standing problem at the interface of theory and experiment. In particular, precision measurements often avoid theory limitations by relying on theory uncertainties to cancel between different control and signal regions, but until now have had no means to reliably quantify the remaining theory uncertainties.
Manufacturing ecosystem of qualified resources exchange

The MANU-SQUARE project creates a European platform-enabled responsible ecosystem acting as a virtual marketplace, bringing available manufacturing capacity closer to production demand to achieve their optimal matching thus fostering, on the one hand, fast and efficient creation of local and distributed value networks for innovative providers of product-services and, on the other hand, reintroduction and optimization in the loop of unused capacity that would be wasted otherwise.
In a wider perspective the MANU-SQUARE project pursues a paradigm shift that disrupts the traditional static supply chain model and establishes dynamic value networks that can be arranged on-demand to couple the needs of buyers and the availability of sellers of manufacturing capacity. In so doing, this latter becomes an easily and efficiently tradable commodity towards lowered production costs for European companies and improved manufacturing ecosystem actual productivity.