SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
The Effects of Different Tillages on Crop Residue Sequestration, Soil Available Nutrients and Some Biochemical Properties in the Chinese Black Soil Region

Abstract Three-year field experiments were conducted to investigate the effects of different tillage operations after harvest on crop residues sequestration and their subsequent effects on soil available nitrogen (N), phosphorus (P), some soil biochemical properties, and three enzymatic activities during the following growing seasons in a soybean ( Glycine max )-soybean-corn ( Zea mays ) rotation farming system in Northeast China. Two different managements were implemented after crop harvest every year, which were tillage (T) and no tillage (NT). Results showed that crop residue masses on soil surface and in the 0-20 cm layer after soybean harvest were about 1 450 and 340 kg ha −1 , respectively, in October 2006 and 2007. While, soybean residue mass in the 0–20 cm soil layer was about 340 kg ha −1 in NT and about 1 550 kg ha −1 in T before sowing in May 2007 and 2008. The adverse results were found after corn crop plantation, that corn residue mass was about 270 and 860 kg ha −1 on soil surface and in the 0–20 cm soil layer, respectively, after harvest in October 2008, while residue mass in the 0–20 cm soil layer was only 466 kg ha −1 in T but 863 kg ha −1 in NT before planting in May 2009. So T had effectively sequestered soybean residue into soil but not corn. Results also showed that T after harvest helped to improve soil available N, P, soil microbial biomass carbon (MBC), and nitrogen (MBN) contents and soil enzymes activities (urease, acid phosphatase, and protease) during the 2007 and 2008 seasons, but the positive effects decreased during the 2009 season. T practice had significant positive effects on available N, P, MBC, and MBN contents, protease and urease activities, however, no obvious effects on acid phosphatase activity. In this study, T practice after soybean harvest was proved to be preferable to improve soil microbial and enzyme activities during the following seasons due to an efficient sequestration of soybean residues. However, NT could be considered preferential after corn crop harvest.
METHODS FOR PRODUCING TRIOL ETHERS BY REACTIVE DISTILLATION

This invention relates to methods for preparing alkyl ethers from glycerin by reactive distillation. For example, the present invention provides a method for the preparation of mono-, di- and tri-ethers of glycerin, either in the presence or absence of fatty acids, contaminants by reactive distillation using solid catalysts. Specific desirable final products according to the reactive distillation method provided herein include glycerin ethers and fatty acid esters of C<SUB>4</SUB>-C<SUB>5</SUB> alcohols, such as for example, isobutanol, tert-butanol, and isoamyl alcohol.
Regulation of Th1/Th17 cytokines and IDO gene expression by inhibition of calpain in PBMCs from MS patients

Multiple sclerosis (MS) pathology is marked by the massive infiltration of myelin-specific T cells into the central nervous system (CNS). During active disease, pro-inflammatory Th1/Th17 cells predominate over immunoregulatory Th2/Treg cells. Here, we show that calpain inhibition downregulates Th1/Th17 inflammatory cytokines and mRNA in MS patient peripheral blood mononuclear cells (PBMCs) activated with anti-CD3/28 or MBP. Interestingly, calpain inhibition elevated IDO gene expression in MS PBMCs, which was markedly decreased in calpain expressing cells. Functional assay showed that incubation of MS patient PBMCs with calpain inhibitor or recombinant IDO attenuates T cell proliferation. These results suggest that calpain inhibition may attenuate MS pathology and augment the efficacy of standard immunomodulatory agents used to treat this disease.
SYSTEM AND METHOD FOR CONTROLLING A TRAILER CONNECTED TO A VEHICLE

An articulated vehicle system can include a first vehicle selectively and pivotally connected to a second vehicle. A first powertrain can be mounted on the first vehicle to drive a wheel mounted on the first vehicle. A second powertrain can be mounted on the second vehicle to drive a wheel mounted on the second vehicle independent from the drive of the wheel of the first vehicle. The vehicle system may also include a controller in electrical communication with each of the first powertrain, second powertrain, and steering mechanism to assist in steering and power distribution, especially when reversing the vehicle system.
Industrial Air Filter Development

GS Inox OÜ has developed an industrial air filter model. The aim of the project is to ensure that the product’s welds are of high quality, i.e. meet the EN ISO 15614-1 standard.
Sediments, dredging, harbor risks

SEDRIPORT (Sediments, Dredging and Port Risks) is a project led by Regione Sardegna in partnership with the VAR department, Cagliari and Toulon Universities, Livorno Province, ARPAL Liguria, ISPRA and the Corsica Transport Office.  The project was created to come up with a joint solution to cross-border ports silting up and operational solutions for the restoration of the seabed. SEDRIPORT capitalises on the contribution of previous projects that provided valuable information on the status of the ports by testing marine environment monitoring systems. It introduces a shared constant monitoring system of silting up, water and sediment pollution, weather and sea conditions and the main chemical and physical parameters of port waters, neighbouring coastal areas and coastal aquifers. Based on current regulations and good practices, it means to implement the Guidelines to be adopted jointly in the cross-border area to address the issue of dredging (restoration of the seabed) and the management of sediments. Climate change causes and speeds up the silting up of ports, which increases environmental and maritime transport economic risks. Being slow in restoring port bottoms undermines the economy and social fabric of entire communities, especially in the islands. Setting standard operating procedures and action plans minimises the adverse effects of silting up and makes port resources more reliable for the local economy with all that follows in terms of guaranteeing the efficiency of the whole cross-border area.
Three-Dimensional Mixed Convection Flow past an Infinite Vertical Plate with Constant Surface Heat Flux

The present paper contains a mathematical analysis of the mixed convection three dimensional steady lami- nar flow of a viscous incompressible fluid past an infinite vertical porous plate. The three-dimensional flow is caused by the transverse sinusoidal suction at the plate. A constant heat flux is prescribed at the plate. Assuming the plate velocity to be uniform, analytical solutions are obtained for the flow field, the temperature field and the skin-friction. Effects of Prandtl number and Grashof number on the flow characteristics are explored and illustrated graphically. In view of the importance of the problems of laminar flow control (LFC), especially in the field of aeronautical engineering, various theoretical and experimental studies of different arrangements and configurations of suction holes and slits have been compiled by Lachmann(1). The suction of the fluid is also an acknowledged technique for control- ling the undesirable features in the boundary layer theory. Further, from the technological point of view, free convec- tion flow and heat transfer problems are always important, for they have many practical applications. The phenomenon of free-convection arises when the difference between the plate temperature and the free stream temperature apprecia- bly large which causes density variations leading to buoyancy forces acting on the fluid elements. This process of heat transfer is encountered in cooling of nuclear reactors, providing heat sinks in turbine blades and aeronautics. Free convection flow past vertical plate has been studied exten- sively by many researchers and some of them are Os- trach(2-3), Stewartson et. al.(4), Sparrow et. al.(5-6), Ma- buchi(7), Riley et. al.(8), Berezovsky et.al.(9), Na(10), Dey et al (11), Kawase et al(12), Martynenko et.al.(13), Weiss et.al.(14) and Pantokratoras(15-16) in numerous ways to include various physical effects. In their work they have restricted themselves to two-dimensional flow only. There may arise situations where the flow fields may be essential- ly three-dimensional, for example when variations in the suction velocity distribution is transverse to the flow direc- tion. Gersten and Gross(17) have studied the effect of such
The ileal neobladder in female patients with bladder cancer: long-term clinical, functional, and oncological outcome

To assess long-term clinical and oncological outcome in women undergoing radical cystectomy and ileal neobladder reconstruction for invasive bladder cancer.From 1995 to 2010, a total of 121 women with clinically organ-confined urothelial carcinoma underwent radical cystectomy with an orthotopic ileal neobladder. Median follow-up was 56 months. Clinical course, functional, pathological, and oncological outcome of these women were analyzed.Seventy-six patients (62.8%) experienced a complication of some type within 90 days of the procedure. 56 patients (46.3%) experienced minor complications, whereas 20 patients (16.5%) experienced major complications. Pathological subgroups included 70 patients (57.9%) with organ confined, lymph node-negative tumors, 24 (19.8%) with extravesical, lymph node-negative disease and 27 (22.3%) patients with lymph node-positive disease. The 5-year overall survival rate in patients with organ-confined (≤pT2, pN0), locally advanced (≥pT3, pN0), and metastatic disease was 80.2%, 81.9%, and 45.1%, respectively. 4 women (3.3%) experienced a local (pelvic) recurrence. One patient presented with a urethral recurrence (0.8%). Daytime and nighttime urinary continence (0-1 pad) was reported by 82.4 and 76.5%, respectively. Clean intermittent self-catheterization was required by 58.0%. The retrospective study design was the major limitation of the study.Despite a considerable complication rate, radical cystectomy with orthotopic diversion in female patients with bladder cancer may be considered a standard therapeutic option for selected patients with excellent oncological outcome including a low incidence of local and urethral recurrence.
ROBUST EGR CONTROL FOR COUNTERACTING EXHAUST BACK-PRESSURE FLUCTUATION ATTRIBUTABLE TO SOOT ACCUMULATION IN A DIESEL PARTICULATE FILTER

An engine (10) uses a method for counteracting the effect of soot accumulation in a diesel particulate filter (DPF 38) in a diesel engine exhaust system (16) on the control of exhaust gas recirculation (EGR) through an EGR system (40). Engine speed (N) and indicated engine torque (TQI) data are processed to select from a map (62) a data value for present EGR volumetric efficiency. The selected data value and certain other data, including data that accounts for present soot accumulation in the DPF, are processed to develop a data value indicative of present total mass flow. The data value indicative of present total mass flow and still other data are processed to develop flow control data for controlling flow of exhaust gas through the EGR system.
[Care management: nurses' actions in a hospital emergency service].

This study aimed to analyze care management actions performed by nurses in a hospital emergency service. This is a qualiative research of the case study type, carried out with nurses from the Emergency Service of a University Hospital in southern Brazil. The data were collected through participant observation and semi-structured interviews, and analyzed using thematic analysis. The results show nurses' actions in care planning, forecasting and provisioning of resources, supervision, leadership and training of the nursing team. In care planning, there is the execution of the nursing process and the control of the realization of laboratory and radiological tests. The actions of forecasting and provisioning of resources were: elaboration of the monthly schedule of employees, daily distribution of the staff and the management of material resources. Leadership encourages the planning of care, the coordination of the nursing staff and the delegation of activities.
Characteristics of Coal and Gas Outburst within Gas Geological Units in Qidong Mine

The precise mechanism of the coal and gas outburst is still unresolved, but productive practices in Qidong mine have testified that the coal and gas outburst accidents are predominantly associated with the belt of geological structure, the zone of tectonic coal occurrence and the area of the stress concentration. So it is very important to study characteristics of coal bed gas geology for coal bed gas prediction and prevention. Using gas-geology theory and method, the research focused on the factors of coal and gas outburst, such as coal bed gas occurrence, stress distribution, tectonic coal occurrence and magmatic rock presence within Qidong mine. The result shows that: Qidong mine district could be divided into 4 geological units by 3 faults as the boundary, the faults of Weimiao fault, F 2 , and F 5 ; there are different conditions and main controlling factors of coal bed gas occurrence within four geological units. The unit I of geology: coal bed gas occurrence conditions are simpler, mainly contacted with the coal burial depth; the unit II: the conditions are more complex, predominantly associated with fault structures; the unit III: as a result of the presence of igneous intrusions, coal bed gas content in unit III is the highest within the whole mine; the unit IV: major factor of the conditions is the fold caused by strata uplift, which also leads to a large number of gas emissions. 25 coal and gas outburst accidents all occurred within the unit II of geology.
Bugs as drugs: understanding microbial interaction networks to prevent and treat infections

Our body is inhabited by an enormous number of microbes which are crucial for our health. The bacteria in our gut for example help us to digest food but can also make us sick in case of an infection. The overall composition and function of those communities are strongly shaped by the interactions of the microbes within them e.g. how the microbes influence each others growth. These interactions are especially important in the case of microbial infections. Since pathogens have to interact with the microbial communities that already inhabit the host, the native microbes can repel or support the pathogens and thus protect the host from diseases or even facilitate them. Although microbial assemblages are pivotal for our health we have currently no satisfying way to get a mechanistic understanding of them which would be crucial to specifically manipulate these communities e.g. for therapeutic interventions. The aim of this proposal is to develop a microscopy method that allows to obtain interaction networks within complex communities. Since bacteria can only share the same space if they tolerate each other but avoid each other in case of competition, interaction networks of complex communities can be derived from the spatial co-occurence of the bacteria that form them. With this technology I especially want to investigate how pathogens embed into the native gut microbial community of the model organism Caenorhabditis elegans. I want to understand how interactions between pathogens and native gut microbiota can protect a host from infections. Finally, I want to use this technology to identify bacteria in the native gut community that can outcompete pathogens and work as specific probiotic against microbial infections. This approach could revolutionize the usage of probiotics and offer completely new ways to prevent and treat infectious diseases, which are especially valuable in times where we see more and more pathogens become resistant against antibiotics.
A Robust Topology-Based Algorithm for Gene Expression Profiling

Early and accurate diagnoses of cancer can significantly improve the design of personalized therapy and enhance the success of therapeutic interventions. Histopathological approaches, which rely on microscopic examinations of malignant tissue, are not conducive to timely diagnoses. High throughput genomics offers a possible new classification of cancer subtypes. Unfortunately, most clustering algorithms have not been proven sufficiently robust. We propose a novel approach that relies on the use of statistical invariants and persistent homology, one of the most exciting recent developments in topology. It identifies a sufficient but compact set of genes for the analysis as well as a core group of tightly correlated patient samples for each subtype. Partitioning occurs hierarchically and allows for the identification of genetically similar subtypes. We analyzed the gene expression profiles of 202 tumors of the brain cancer glioblastoma multiforme (GBM) given at the Cancer Genome Atlas (TCGA) site. We identify core patient groups associated with the classical, mesenchymal, and proneural subtypes of GBM. In our analysis, the neural subtype consists of several small groups rather than a single component. A subtype prediction model is introduced which partitions tumors in a manner consistent with clustering algorithms but requires the genetic signature of only 59 genes.
A novel in vivo platform to study and target undruggable ewing onco-chimera.

Development of efficient therapeutic strategies in the past years has drastically reduced the lethality of several common types of pediatric and juvenile form of cancer such as leukemia, lymphoma and brain tumors. Such a tremendous success, however, does not include sarcomas treatment, whose mortality rate remains the same as twenty years ago. 
Ewing sarcoma is a childhood cancer with a relatively low incidence, with 3 cases/million/year. The initial oncogenic event is represented by a balanced chromosomal translocation originating a transcription factor chimeric onco-protein. Notably, 90% of Ewing sarcoma patients are characterized by the fusion between EWS and FLI1 genes. From a therapeutic point of view, as exclusive hallmark of tumor cells and driving force of the disease, the onco-chimera protein represents an ideal target, even though transcription factor onco-proteins are classified as “undruggable” from a conventional pharmacological point of view, lacking in their structure convenient targeting pockets. 
This project aims to break this dogma through the following steps: 1. Generation of an in vivo genetic platform based on an innovative ex vivo-in vitro-in vivo approach that will allow us to accurately recapitulate in mice Ewing sarcomagenesis; 2. Characterization in vivo and in vitro of those mechanisms and pathways that are essential for the tumorigenic process; and finally, 3. Identification of druggable targets whose fine-tuning will tear down Ewing sarcoma lethality by promoting onco-chimera degradation. 
The success of this project will not only lead to the development of new therapies against Ewing sarcoma, but also to the development of a novel platform which will be easily exported to other tumors driven by “undruggable” onco-chimeras.
Biological evaluation of 3-[18F]fluoro-α-methyl-d-tyrosine (d-[18F]FAMT) as a novel amino acid tracer for positron emission tomography

Objective3-[18F]Fluoro-α-methyl-l-tyrosine (l-[18F]FAMT) is a useful amino acid tracer for positron emission tomography (PET) imaging of malignant tumors. Because d-amino acids are not well distributed in non-target organs and are rapidly excreted in urine, the d-isomer of [18F]FAMT could allow clear PET imaging of tumors early after administration. In this study, we prepared 3-[18F]fluoro-α-methyl-d-tyrosine (d-[18F]FAMT) and evaluated its usefulness.Methods d-[18F]FAMT was synthesized according to the method for preparation of l-[18F]FAMT. The in vitro and in vivo stability of [18F]FAMT were evaluated by high-performance liquid chromatography. Cellular uptake of [18F]FAMT was evaluated using LS180 colon adenocarcinoma cells. Biodistribution studies were performed in LS180 tumor-bearing mice, and the tumors were imaged using a small-animal PET scanner.ResultsThe radiolabeling yield of d-[18F]FAMT was approximately 10 %, similar to that of l-[18F]FAMT. Over 95 % of d-[18F]FAMT remained intact in mice until 60 min after administration. d-[18F]FAMT was gradually taken up by the LS180 cells. Tumor uptake of d-[18F]FAMT was competitively inhibited by pretreatment with α-methyl-l-tyrosine, a selective substrate for the system l-amino acid transporter 1 (LAT1), suggesting the involvement of LAT1 in tumor uptake of d-[18F]FAMT. In biodistribution studies, d-[18F]FAMT showed rapid clearance from the blood, marked accumulation and retention in the tumor, and lower accumulation in non-target organs, especially kidney and pancreas, compared to l-[18F]FAMT. The amount of d-[18F]FAMT in the tumor was also reduced, and tumor-to-blood ratio and tumor-to-muscle ratio of d-[18F]FAMT were similar to those of l-[18F]FAMT at every time point. PET imaging with d-[18F]FAMT did not provide a clear image of the tumor early after administration. However, d-[18F]FAMT provided higher tumor-to-background contrast than l-[18F]FAMT.Conclusions d-[18F]FAMT showed rapid blood clearance, low accumulation in non-target organs, and tumor-selective imaging compared with l-[18F]FAMT. Thus, d-[18F]FAMT could potentially serve as a novel PET tracer for imaging malignant tumors.
staysafe@conventodoseixohotel

Adaptation of the Convent of Seixo Boutique Hotel & SPA to the new operating conditions in the context of the COVID-19 pandemic, ensuring compliance with the established standards and recommendations of the competent authorities in order to ensure the minimum impact on public health.
Acupuntura no Tratamento da Acne / Acupuncture in the Treatment of Acne

A estimulação de pontos de acupuntura tem mostrado efeito benéfico no tratamento da acne, no entanto, falta uma avaliação abrangente das evidências clínicas atuais. O objetivo desta revisão foi avaliar as pesquisas realizadas nos últimos 5 anos sobre o tratamento da acne por acupuntura. Foi realizada uma revisão integrativa utilizando como base de dados o Portal Regional da Biblioteca Virtual de Saúde. Quatro artigos participaram desta revisão. Todos os artigos encontrados eram artigos de pesquisa, propondo uma pesquisa, informando a metodologia utilizada para avaliar o tratamento da acne por acupuntura. A conclusão deste estudo é que de acupuntura não tem evidência para o tratamento da acne. Embora algumas pesquisas já apontem efeitos benéficos deste tratamento, mais estudos grandes e rigorosamente projetados são necessários para confirmar esses achados.Abstract: Stimulation of acupuncture points has shown a beneficial effect in the treatment of acne, however, a comprehensive assessment of current clinical evidence is lacking. The purpose of this review was to evaluate the research carried out in the last 5 years on the treatment of acne by acupuncture. An integrative review was carried out using the Regional Portal of the Virtual Health Library as a database. Four articles participated in this review. All the articles found were research articles, proposing a research, informing the methodology used to evaluate the treatment of acne by acupuncture. The conclusion of this study is that acupuncture has no evidence for the treatment of acne. Although some research already points to beneficial effects of this treatment, more large and rigorously designed studies are needed to confirm these findings.