SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
The Power of Sound: How to Be Healthy and Productive Using Music and Sound

Acknowledgments Preface: 2010 and Moving Forward--The Decade of Sound! Introduction Part One Sound 1 What Is Sound? 2 The Physics of Sound 3 The Mechanics of Hearing 4 Resonance, Entrainment, and Pattern Identification 5 Frequency Medicine: The Work of Alfred Tomatis Part Two Sound Awareness 6 A New Awareness of Sound 7 Sonic Safety 8 Neuroscience and Music 9 Music and Sound in Your Life 10 Progressive Sound Health for the Hospital Environment 11 Animals and Sound 12 Current Sonic Media Part Three A Guide to Soundwork Techniques and Applications 13 A Matter of Distinctions 14 The Building Blocks of Therapeutic Sound 15 Sonic Neurotechnologies 16 Applied Psychoacoustics for Health Care Practitioners 17 Advanced Sound Tools and Techniques 18 The Anatomy of Psychoacoustic Music Creation 19 The Sound and Music Alliance (SAMA) Epilogue Glossary ThePowerOfSound.com Sound Remedies Catalog Music for The Power of Sound CD Track Listing Notes Bibliography About the Author Index
UNIVERSAL PAYLOAD ABSTRACTION

Robotic payloads are abstracted to provide a plug-and-play system in which mission specific capabilities are easily configured on a wide variety of robotic platforms. A robotic payload architecture is presented in which robotic functionalities are bifurcated into intrinsic capabilities, managed by a core module (210), and mission specific capabilities, addressed by mission payload module(s) (220). By doing so the core modules manages a particular robotic platform's intrinsic functionalities while mission specific tasks are left to mission payloads. A mission specific robotic configuration can be compiled by adding multiple mission payload modules to the same platform managed by the same core module. In each case the mission payload module communicates with the core module for information about the platform on which it is being associated.
Risk factors for poor outcomes in patients with open-globe injuries

The aim of this study was to identify the risk factors that are predictive of poor outcomes in penetrating globe trauma.This retrospective case series evaluated 103 eyes that had been surgically treated for an open-globe injury from 2007 to 2010 at the eye clinic of the University of Virginia. A total of 64 eyes with complete medical records and at least 6 months of follow-up were included in the study. Four risk factors (preoperative best-corrected visual acuity [pre-op BCVA], ocular trauma score [OTS], zone of injury [ZOI], and time lapse [TL] between injury and primary repair) and three outcomes (final BCVA, monthly rate of additional surgeries [MRAS], and enucleation) were identified for analysis.Pre-op BCVA was positively associated with MRAS, final BCVA, and enucleation. Calculated OTS was negatively associated with the outcome variables. No association was found between TL and ZOI with the outcome variables. Further, age and predictor variable-adjusted analyses showed pre-op BCVA to be independently positively associated with MRAS (P=0.008) and with final BCVA (P<0.001), while the calculated OTS was independently negatively associated with final BCVA (P<0.001), but not uniquely associated with MRAS (P=0.530).Pre-op BCVA and OTS are best correlated with prognosis in open-globe injuries. However, no conventional features reliably predict the outcome of traumatized eyes.
DISTRIBUTED, DIODE MIXER CIRCUIT

A distributed, diode mixer circuit includes a plurality of passive diode mixer cores including at least first and second passive diode mixer cores including doubly-balanced diodes in symmetrical balanced configuration forms, each mixer core having a pair of differential reference nodes driven by the reference signal and a pair of differential nodes driven by the data signal and a reactive impedance network including one or multiple reactive elements or transmission lines connected between the like nodes of each the first and second mixer cores.
Understanding gamma delta t cells in colon cancer metastasis

Cancer is the leading cause of death in the world. Immunotherapy is having a major impact in counteracting these cancer-related deaths, since the activity of anti-tumour immune cells can be enhanced to kill cancer. Unfortunately, immunotherapy does not work for every patient, so we must understand how other immune cells participate in cancer progression to design new immunotherapies that may benefit a greater number of patients. One particular type of immune cell, called gamma/delta T cells, was recently shown by my Host to promote breast cancer metastasis via IL-17, an important pro-tumour cytokine. However, the significance of gamma/delta T cells and IL-17 in other cancer metastasis settings remains unclear. In this proposal, I will address this point using a newly developed sophisticated colorectal cancer metastasis model. This novel mouse model shows 100 percent penetration of metastasis, of which 80 percent is to the liver, similar to human colorectal metastasis. Using this metastasis model, I will: 1. Clarify characteristics of gamma/delta T cells in colorectal cancer metastasis, 2. Assess if depletion of gamma/delta T cells by a neutralizing antibody as well as crossing the model with gamma/delta T cell-deficient mice would reduce the occurrence of metastasis, and 3. Examine the involvement of BTNL1, which is a specific activator for anti-tumorigenic IFN-producing gamma/delta T cells in the intestine. The role of BTNL1 in any cancer setting and the importance of IL-17-producing gamma/delta T cells in colon cancer metastasis is largely unexplored. Addressing our goal to understand the role of these gamma/delta T cells in colon cancer metastasis, I will newly acquire expertise and technical skills in both immunology and cancer biology as well as have experience in excellent collaboration with several laboratories. This proposal will identify additional targets for immunotherapy that may help patients with metastatic colon cancer.
Time-Dependent Spatial Amplitude Patterns of Harmonic Tremor at Arenal Volcano, Costa Rica: Seismic-Wave Interferences?

Seismograms recorded at the receivers of a small‐aperture seismic array usually display very similar waveforms and amplitudes, as a consequence of their close proximity. During the analysis of the volcanic tremor wave field at Arenal volcano, Costa Rica, we detected significant differences in the amplitudes of harmonic tremor recorded at the stations of a small‐aperture (∼210  m) seismic array. The amplitude distributions are geometrically complex and characterized by strong gradients. They occur just for harmonic tremors; any other type of seismic event produces nearly uniform amplitudes across the array. This suggests some relation with harmonic frequency content. Moreover, the spatial amplitude patterns change with time. Some of these observations could be explained by an extreme combination of source, path, and site effects. But they also could be produced by interference of different components of the seismic wave field. We use numerical calculations to investigate the amplitude pattern generated by two interfering plane waves, and are able to reproduce the main features of the observed amplitude patterns. We propose mechanisms that might generate seismic wave fields with multiple components and conclude that interference can explain the complexity and variability of the harmonic tremor wave field at Arenal volcano.

Online Material: Wave‐field animation.
Regional Development Agencies Network in the Central European, Danubian and Adriatic Area ²

RDA-net CEDA² is a network of regional development agencies (RDAs) with a complete set of services and tools for fostering and improving the partners' capabilities in practical cooperation vis-à-vis the challenges of EU enlargement. RDA-net CEDA² aims to: - Generate innovative projects for regional development of CADSES by using the synergies of the network's experts, - Increase the competencies and human resources for management and implementation of regional development projects, especially in a transnational and cross-border context in connection with Community Initiatives and Structural Funds, - Promote sharing and exchanging information on regional development issues, - Extend the network of regional development experts and multiply its synergy potential for CADSES in terms of co-operation opportunities and a broad territorial coverage, - Become a "network of competence" providing national and regional governments with recommendations, advice and support on spatial development issues and policies; establishment of a "virtual resource centre" for methods, approaches and projects of regional development in a transnational and cross-border context must be examined.
The synthesis, self-assembling, and biocompatibility of a novel O-carboxymethyl chitosan cholate decorated with glycyrrhetinic acid

O-carboxymethyl chitosan (OCMC) was firstly decorated with cholic acid (CA) to acquire an amphiphilic polymer under alkaline condition. Then glycyrrhetinic acid (GA) was conjugated to the polymer via a succinate linker and finally treated with NaCO3 solution to obtain new conjugates for potential liver targeted delivery. These conjugates formed uniform aggregates with low critical aggregation concentrations (0.028-0.079 mg/mL) in PBS. The average diameter of cholic acid modified carboxymethyl chitosan (CMCA) aggregates (110-257 nm) decreased with the increase of CA substitution degree and became slightly larger after GA modification. Negative zeta potential (-15 mV) of GA decorated CMCA (GA-CMCA) revealed that the formation of negatively charged shells and spherical morphology was observed under transmission electron microscopy. Furthermore, hemolysis test, in vitro cytotoxicity assay and cellular uptake study all demonstrated the safety and feasibility of these conjugates as a promising carrier for liver targeted drug delivery.
Actualidad y futuro del pensamiento de Eugenio Coseriu. Estudios de teoría del lenguaje, descripción lingüística, dimensión textual y lingüística peruana

Este volumen, que conmemora el centenario del nacimiento de Eugenio Coseriu, ha reunido a una serie de especialistas que proponen valoraciones teóricas y empíricas sobre la actualidad del pensamiento coseriano, así como su aplicación a disciplinas que el profesor de Tubinga no abordó o solo hizo tangencialmente. Los autores han desarrollado sus reflexiones a través de los temas del trinomio lingüística, filosofía de la lingüística y filosofía del lenguaje; asimismo, han abarcado aspectos textuales y algunas de las lenguas del Perú. De esta manera, la obra se estructura en torno a cinco bloques: "Eugenio Coseriu: vida y obra", "Teoría del lenguaje", "Conceptos y categorías para la descripción lingüística", "La dimensión textual" y "Lingüística peruana". La obra, dirigida desde Perú por Carlos Garatea Grau y Jorge Wiesse Rebagliati y coordinada desde Sevilla por Marta Fernández Alcaide constituye una muestra de la continuidad y fecundidad del legado del maestro rumano y refleja la proyección con la que conectó el continente americano y el europeo, de ahí que la nómina de autores esté constituida por investigadores de ambas zonas geográficas.
Evolution and development of pharyngeal pouches and pre-oral gut in basal fishes

Vertebrates, which include our own species, are the most diverse and successful group of Deuterostomes. Success of this group has been explained by the evolution of elaborated head skeleton adapted to capturing and processing large prey. Most of this skeleton derives from neural crest cells migrating into the pharynx during and after the formation of pharyngeal pouches. To better understand how development of these structures evolved, the research project will study representatives of three basal fish lineages that occupy key positions in jawed-vertebrate phylogeny. It will employ methods of genomics, gene expression, and gene manipulation including CRISPR/Cas9 gene editing system to test a mechanistic model of pouch formation and its relationships to pre-oral endoderm development. The proposal builds upon the Fellow’s research of jawed and jawless vertebrates and bridges a gap in our knowledge of the pharyngeal evolution between the jawed and jawless vertebrates and at the same time between vertebrates and their chordate and deuterostome ancestors. Two-way knowledge transfer is a crucial feature of this project: the Fellow will take advantage of the proficiency of the Supervisor and the Department in embryology, morphology, manipulation, and husbandry of the rare basal fishes and in the genomics and transcriptomics, while at the same time he will transfer his expertise in genetic regulation of development and CRISPR/Cas9 gene editing in non-model organisms to the Supervisor and Host Institution.
Yamatology of the axis. japan as a nazi-fascist utopia of political renewal

After his arrest for mass murder, the Norwegian terrorist Andres Breivik declared “that a Japanese would understand him a lot better than any European would”, because “the Japanese understand the idea and values of honour”. Shortly before committing suicide in the Notre Dame Cathedral in Paris on 21st May 2013, the French new right thinker Dominique Venner wrote a book in which he depicted himself as a ‘samurai’ who fought in defence of European identity. These are just two of the many examples of the role played by a certain image of Japan in far-right imagination of our time. 
This project investigates the origins and development of the political discourses on Japan – something that can be called ‘yamatology’ instead of japanology – by focusing on the historical moment in which they reached its wider dissemination and became integral parts of far-right ideologies. The aim of this project is, therefore, to analyse comparatively the discursive construction of the image of Japan in Nazi Germany and Fascist Italy. Instead of offering an overview on the European representations of Japan or focusing on a national case study, this project will carry out a detailed analysis of Nazi-Fascist yamatological representations, by considering them as result of a dialogical interaction between European and Japanese actors, as well as a constituent element of the Axis’ cultural policies closely related to many of the ideological features shared by both Fascism and Nazism. The project’s ultimate goal is to highlight the utopian dimension of yamatological representations, in which Japan – just like it did for Breivik or Venner – became the projection surface for far-right values and political aspirations. In doing so, this project allows re-thinking of the nature of fascism, both stressing a substantial similarity between Nazism and Fascism, and revealing the influence of non-European models on ultra-nationalist and Eurocentric world views.
FOCUS Technologies

The dynamics in the development of information technologies and the penetration of web-based solutions in all aspects of business and commercial activity increase the requirements for developers — both in technical terms and in terms of terms of implementation of specialised services. This is why the strategic goal of Skale FOCUS AD and this project is to achieve quality improvement of existing services and implementation of new ones for testing when making changes in the electronic systems of customers. In this regard, the project envisages the implementation of the following two main activities:1. Activity to add new features or improve existing products and services2. The activities will be realised through the purchase and implementation of 7 types of assets — specialised equipment and software, with expected results of increasing exports, achieving higher productivity, increasing the added value of services and products, improving the efficiency of costs and inputs.
Fast-Bm: fibroselect: delivering a step-change in biotherapeutic manufacturing

Seven of the top 10 global medicines by spending are biotherapeutics drugs, and the market is growing at a CAGR of 10.1% to reach a value of $287 billion in 2020. 

Challenges facing biotherapeutic manufacture are: i) Chromatographic purification, accounting for >50% of processing costs. This is important given the increasing price sensitivity of payers worldwide and serves as a limitation to the growth of the biosimilar industry; ii) Increasing diversity and complexity of biotherapeutics: ~70% of biopharma’s product pipeline are large complex proteins (e.g. bispecific antibodies, fusion proteins or viral vectors), which offer promising therapeutic opportunities, but cannot be manufactured cost effectively as they do not fit with current bioprocessing platform technologies; iii) Process flexibility: The rapidly evolving industry is moving to more flexible disposable formats to cope with uncertainty in drug development and varying market demand. 

Puridify has developed an innovative bioprocessing platform technology, FibroSelect, a functionalised cellulose chromatography medium to enable high-productivity, product capture and purification that is economic to operate in a disposable manner. 

FibroSelect addresses each point above by i) enabling cost reductions of up to 25% (potentially £700K - £2.7m per batch); ii) offering flexibility to design new bioprocessing platforms; iii) being a wholly disposable system where all purifying ligand is expended per-batch purification. It is innovation in the latter area that helps to drive costs down and increase productivity, as the requirement for cleaning columns and re-validating prior to purification of the next batch of biotherapeutic product is ameliorated. FibroSelect eases process constraints and enables flexibility through single-use processing opportunities thereby maximising facility utilisation as has been seen with the rapid growth in use of single-use technologies for manufacturing.
Help startups to scale by leveraging the access to european markets offered by four major startup hubs

The Access2Europe project has one main goal: cut through the maze of information available online and bring the right people together in order to multiply the chances of the European startups to scale and grow turnover and retain qualified employees. Ultimately, the connections created will reach ‘critical mass’ and create a de facto pan-European ecosystem.
Building on the strong regional presence of the partners, the Access2Europe proposal is a scalable and agile concept for the successful acceleration of EU startups into maturity. The partners envisioned the Access2Europe project as a series of 3 programmes running in parallel, all meant to provide entrepreneurs with the right answers from the right contacts. The programmes will range from 3 month long full immersion into another ecosystem to a 3-day market discovery, to a quick 1-hour update on latest work legislation. The goal is to strengthen company growth within the EU (thus avoiding quick exits or move across the ocean) and to cross-pollinate the involved European startup ecosystems turning them into hubs of a diffused European startup ecosystem.
Multipath routing can adapt to traffic changes, increase reliability and enhance the Quality of Service support in communication networks. This routing algorithm has been recognized as one of the salient features in Mobile Ad hoc Networks (MANETs). However, existing multipath routing protocols are often practically infeasible due to its security venerability if they suffer from attacks in MANETs, such as repudiation attacks, Denial of Service attacks. In this paper we propose a novel secure multipath routing protocol, referred to as SMRP, and investigate its feasibility and performance. SMRP applies a new heuristic algorithm increasing the number of disjoint paths and a smart authentication mechanism to enhance the security against the attacks in MANETs. The performance results from extensive analysis and experiments show that SMRP can efficiently enhance the security in MANETs while preserving the low overhead of computing and communication. Copyright © 2009 John Wiley & Sons, Ltd.
A PRINTING SUBSTRATE

The invention relates to a printing substrate for gravure and offset printing, which substrate exhibits a Cobb(w15) water absorption value below 15 g/m2, preferably below 12 g/m2, a Cobb(o,C10) oil absorption value below 1.2 g/m2, preferably below 1 g/m2, and an Ink setting below 0.5, preferably below 0.3. The low water and oil absorption in combination with the quite fast ink setting of the substrate according to the invention gives rise to a printed substrate with improved printing qualities.
Additional file 3 of Increasing Children’s physical Activity by Policy (CAP) in preschools within the Stockholm region: study protocol for a pragmatic cluster-randomized controlled trial

Additional file 3.
Hybrid drug-loaded plasmonic photothermal microneedle patch against skin infections

In this proof of concept project, we will assess the technical and commercial feasibility of a hybrid microneedle patch for the treatment of nosocomial skin infections caused by drug resistant bacteria. Not only does this device permeate difficult-to-penetrate skin layers to deliver antibiotics locally, it also weakens bacterial defences by raising local temperature to enhance drug effectiveness. In this manner, the need for high dosage systemic drug administration is avoided – reducing occurrence of associated side-effects and perpetuation of antimicrobial resistance. It holds the potential not only to revitalise antibacterials for topical, local treatment of skin infections, but to improve dermatological drug delivery as a platform device. In this project, we will validate the device’s fabrication process for additional commercial scalability and functionality with nanocarrier-drug complexes (for enhanced effectiveness of drug delivery to target site), develop a robust IP strategy and secure initial patents, and conduct extensive market analyses and competitor landscaping. Finally, we will formulate a strong business case, and depending on the results of these activities, establish a company.
Diversidade genética entre genótipos de cártamo via caracteres

O cártamo (Carthamus tinctorius L.) é uma oleaginosa herbácea com características que permitem seu cultivo em regiões áridas e semiáridas. Assim, a caracterização de diferentes genótipos de cártamo, é um passo importante na obtenção de informações básicas para programas de melhoramento desta cultura. Neste contexto, o objetivo deste trabalho foi avaliar a divergência genética entre genótipos de cártamo com base em características morfológicas, a fim de fornecer orientações iniciais para programas de melhoramento genético. Foram avaliados 124 genótipos de Carthamus tinctorius L. oriundos do Banco Ativo de Germoplasma do Instituto Mato-grossense de Algodão e Laboratório de Recursos Genéticos Vegetais da Universidade do Estado de Mato Grosso, Campus de Cáceres. Os genótipos foram avaliados quanto a 16 caracteres morfológicos e os dados submetidos a análise multivariada pelo método UPGMA de agrupamento. As estimativas dos coeficientes de dissimilaridade variaram de 0,00 a 0,56, indicando presença de diversidade genética entre os genótipos avaliados. Os agrupamentos estabelecidos no método Tocher e UPGMA apresentaram diferenças nos grupos formados, mudando completamente a composição destes. Com isso, existe variabilidade genética entre genótipos de cártamo avaliados com base nas características morfológicas, sugerido a utilização destes em futuras combinações em programa de melhoramento genético da cultura.