SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Active implants: engineering microstructures of functional ceramics for stimulated bone growth

The aim of this study is to develop piezoelectric ceramics for the use as bone replacement materials utilizing their piezoelectric behaviour to stimulate bone and vascular cell growth. The work is based on the finding that mechanical and electrical stimuli exert a strong influence on the osseogenesis on the cellular level. As piezoelectric ceramics develop electric surface charges under mechanical load it is expected that they accelerate the healing process and support the development of a strong bond between bone and implant.
The quality of bone and vascular ingrowth is determined by various factors such as biocompatibility of the replacement material, surface morphology and electric surface states. Especially the porosity of the ceramic is of crucial importance as the pores have to be large enough and of open structure to allow ingrowth of both bone and vascular cells. However, increasing porosity is likely to alter the local piezoelectric behaviour and by this the local surface charges responsible for cell growth stimulation. To pave the way for the development of piezoelectric implants it is crucial to understand the influence of microstructural features such as porosity and grain size on the piezoelectric properties. I will approach this task by developing biocompatible ceramics with a wide range of microstructural characteristics. I will investigate the influence of porosity and grain size on a macroscopic scale using piezoelectric testing techniques, on a mesoscopic scale employing Piezo Force Microscopy and on the structural scale via diffraction studies. The biocompatibility as well as the influence of the piezoelectric behaviour on the osseogenesis will be clarified by in-vitro cell experiments on unpoled and electrically poled ceramics. The knowledge gained will form the basis for the development of a new class of implant materials exploiting the piezoelectric characteristics to improve the healing process and to create long lasting interfacial bonds.
Implementierung von Produktinnovationen zur Verbesserung der Wettbewerbsfähigkeit des Unternehmens

Das Unternehmen ist spezialisiert auf die Herstellung von Verbundwerkstoffen für die Automobilindustrie von hoher Qualität, die auf dem heimischen Markt unerreichbar ist. Das Projekt wird die Ergebnisse von F & E-Arbeiten, die unabhängig vom Unternehmer durchgeführt werden, sowie Produkt- und nichttechnologische Innovationen umsetzen. Das neue Produkt – Carbon Dachbox für Ultrasportwagen und Luxusautos wird es ermöglichen, das Sortiment des Unternehmens zu erweitern und dadurch neue Märkte zu erschließen und den Umsatz zu steigern. Darüber hinaus wird im Rahmen des Projekts ein neuer, nachhaltiger Arbeitsplatz geschaffen. Der Umfang des Projekts wurde auf der Grundlage einer Analyse und Bewertung der technologischen Bedürfnisse des Unternehmens unter Berücksichtigung der Erwartungen und Bedürfnisse der Empfänger entwickelt. Die Umsetzung der Investition wird die Wettbewerbsfähigkeit des Unternehmens auf den regionalen, nationalen und internationalen Märkten direkt steigern.
Analogue indicating organ in crystalline material, timepiece provided with such an indicating organ, and manufacturing method thereof

The hand (10) includes a main body (11) which is made of crystalline material containing silicon and is formed by micromachining a silicon wafer (12). The body has an upper surface including geometrical relief patterns and facets, and an integrated circuit unit is arranged in the main body. A metallic deposit is formed on the geometrical relief patterns to provide an outer metallic printed-pattern aspect to the hand. An independent claim is also included for a method for manufacturing an analog display unit for a timepiece.
Directly modulated lasers on silicon

DIMENSION establishes a truly integrated electro-optical platform, extending the silicon (Bi)CMOS and silicon photonics platform with III-V photonic functionality. The III-V integration concept is fully CMOS compatible and offers fundamental advantages compared to state-of-the art integration approaches. After bonding and growing ultra-thin III-V structures onto the silicon front-end-of-line, the active optical functions are embedded into the back-end of line stack. This offers great opportunities for new innovative devices and functions at the chip-level but also for the assembly of such silicon devices. As processing takes place on silicon wafers, this project has the unique opportunity to bring the cost of integrated devices, with CMOS, photonic and III-V functionality, down to the cost of silicon volume manufacturing. Such a platform has the potential to allow Europe to take a leading position in the field of high functionality integrated photonics. Moreover, the project demonstrators adhere to standards such as IEEE802.3, 25G optical components and low-power electronics, thus opening a viable route towards ultra-low-cost high-performance optical transceivers for a new era of data centres and cloud systems. DIMENSION will realise three demonstrators:
• A short-reach transmitter for intra-datacenter operation addressing the 400 GbE-LR8 (IEEE 802.3bs) standard making use of an array of directly modulated lasers, pulse-amplitude-modulation (PAM4) techniques and 8 wavelength channels in the telecom O-band.
• A medium-reach transmitter for inter-datacenter applications beyond the 400 GbE-LR8 (IEEE 802.3bs) standard by providing a tuneable coherent transmitter for inter-datacenter and metro applications for link lengths in excess of 10km using a modulator integrated on the same chip.
• A novel laser directly grown on silicon photonics, operated at 25Gb/s in the telecom O-band demonstrating the significant cost-saving potential of the technologies pursued in DIMENSION.
Testing lepton flavour universality in excited strange mesons

Our understanding of all known particles and their interactions is successfully described in the Standard Model (SM). It is, however, known to be incomplete since it does not explain e.g. dark matter, or the matter-antimatter asymmetry in the universe. Recently, several experiments found hints of physics beyond the SM, which must be further investigated.

A key assumption of the SM is that leptons (electrons and their heavier siblings, muons and taus) have the exact same couplings to forces, called lepton universality. When testing this assumption using decays of so-called B mesons, three independent experiments found increased values for their decay rate to a D meson and tau lepton, compared to a D meson and a muon. This could be explained by the existence of new particles, such as leptoquarks, which couple more strongly to leptons with a higher mass.

This proposal concerns a similar measurement using strange B mesons (Bs), which decay into strange D mesons (Ds). The D mesons that were measured before are extremely difficult to distinguish from their so-called resonance states, which are excitations of the D meson. Misidentifying these could wrongly increase the rate of tau decays of all three experiments. Ds mesons, on the other hand, have a different structure of resonances, and fewer exist that can mimic the signal. Additionally, these can be constrained using their well-defined kinematics. As such, an observation of non-universality in the Bs meson decays would provide conclusive evidence for the existence of physics beyond the SM.

In 2021, the LHCb experiment will recommence data-taking with a completely new detector and reconstruction software. Dr. Klaver plays a key role in studying the impact of misaligned or misplaced detectors and detector defects of the upgrade detector. This proposal describes how a validation framework is to be set up to aid the commissioning of the new experiment. This secures future tests of lepton universality with high precision.
Technologies of imaging in communication, art, and social sciences

In the face of images’ proliferation in all areas of human life, we can talk about the necessity of education on how to adjust to and operate in visual space, to read even and develop the language reflecting such culture. 
In response to the above mentioned social challenges, we have developed a subject of our scientific interest, which is reading images in spaces of transfer (mobility) of people in urban visual environment and across different cultures.
We want to conduct our research at the airports, in trains and on metro stations, in parking lots, elevators, corridors (at the academies and universities, but also in tunnels), and in public transport (buses, trams, cabs and underground).
The main problem is that in educational programs there is a lack of teaching students how to read and interpret visual communicates present in social spaces, which is indispensable for culturally developed and conscious communication on a global scale.
Therefore, we have to realize the TICASS project to introduce into educational programmes visual literacy and to contribute to the development ofawareness of cultural specifics of visual literacy in business.
The project will be realized by means of secondments between European and African Partners, during which we will conduct seminars, trainings,workshops, research and elaborate artistic exhibitions. There will be also delivered reports on education and three anthologies.
The project on technologies of imaging is an unprecedented within social sciences and humanities, because in educational programs there is no teaching how to read and interpret visual communicates present in social spaces.
The research outputs will be shared also with market representatives, because the analysis of meanings and ways of functioning of images and technologies of imaging in different coutries can serve also conscious business (media, IT, design, creative industries).
Institutions in consumer credit

Whether (and why) the market for consumer credit is inefficient is still an open question with important implications for household well-being. The research in this proposal will study sources of inefficiencies in two burgeoning consumer credit institutions: high-cost credit and on-line marketplaces. Each institution serves borrowers on opposite ends of the wealth and credit risk spectrum. Thus, they provide an ideal laboratory for studying the wide range of economic frictions that shape the access and price of credit for households. Despite growing attention from academics and severe scrutiny by policymakers, the economic and social impact of both institutions are yet not well understood.

The first stream of projects in the proposal is aimed at providing new evidence on the trade-offs involved in the use of high-cost credit. High-cost credit, such as Payday loans, is often the only source of funding for poor households. Alleviating liquidity shortages with high-cost credit may have negative long term consequences for financial health, an effect often attributed to borrower self-control problems. In the first project of the stream I use data from a Payday lender in the U.K. to explore a new channel for this effect—reputation—that does not rely on borrower irrationality. The second project combines data from 21 police forces in the U.K. to evaluate the social consequences of high-cost credit through the lens of criminal behavior.

The second stream of projects characterizes previously unexplored sources of adverse selection in credit markets, with substantive positive and normative implications. Using data from the largest on-line marketplace in the U.S., I aim to demonstrate how asymmetric information distorts maturity choice, and how information gathering by the lender can drive away low-risk borrowers. The final project of this stream will use previously unavailable data to produce the first comprehensive characterization of on-line credit marketplaces worldwide.
Application of dGNSS in Alpine Ski Racing: Basis for Evaluating Physical Demands and Safety

External forces, such as ground reaction force or air drag acting on athletes' bodies in sports, determine the sport-specific demands on athletes' physical fitness. In order to establish appropriate physical conditioning regimes, which adequately prepare athletes for the loads and physical demands occurring in their sports and help reduce the risk of injury, sport-and/or discipline-specific knowledge of the external forces is needed. However, due to methodological shortcomings in biomechanical research, data comprehensively describing the external forces that occur in alpine super-G (SG) and downhill (DH) are so far lacking. Therefore, this study applied new and accurate wearable sensor-based technology to determine the external forces acting on skiers during World Cup (WC) alpine skiing competitions in the disciplines of SG and DH and to compare these with those occurring in giant slalom (GS), for which previous research knowledge exists. External forces were determined using WC forerunners carrying a differential global navigation satellite system (dGNSS). Combining the dGNSS data with a digital terrain model of the snow surface and an air drag model, the magnitudes of ground reaction forces were computed. It was found that the applied methodology may not only be used to track physical demands and loads on athletes, but also to simultaneously investigate safety aspects, such as the effectiveness of speed control through increased air drag and ski-snow friction forces in the respective disciplines. Therefore, the component of the ground reaction force in the direction of travel (ski-snow friction) and air drag force were computed. This study showed that (1) the validity of high-end dGNSS systems allows meaningful investigations such as characterization of physical demands and effectiveness of safety measures in highly dynamic sports; (2) physical demands were substantially different between GS, SG, and DH; and (3) safety-related reduction of skiing speed might be most effectively achieved by increasing the ski-snow friction force in GS and SG. For DH an increase in the ski-snow friction force might be equally as effective as an increase in air drag force.
Towards quantum states of matter via chemistry under extreme conditions

Quantum materials hold the promise to spark the next technological revolution; the realization of quantum computers, high-speed electronic devices, or cheap energy delivered over superconducting wires could transform our society. However, the experimental realisation of such devices is slow to develop due to a lack of understanding of crucial underlying quantum phenomena. Magnetic systems with low dimensionality could provide one of the most important avenues for the realisation of exotic quantum states of matter. Yet the exploration of the properties and applications of quantum materials relies on advances in synthesis techniques. With the aim of expanding the frontiers of quantum materials, this project aims to explore low dimensional quantum systems under extreme conditions of temperature and pressure. Motivated by finding quantum states of matter, the synthesis of new magnetic phases with a one-dimensional and two-dimensional arrangement of spins is targeted. Firstly, the realization of 1D quantum magnetism in quasi-one-dimensional La3MoO7 by chemical and physical means will be explored. Secondly, the realization of spin ½ decorated anisotropic Shastry-Sutherland lattice in the quasi-two-dimensional SrCu2(BO3)2 system by chemical doping (on both A- and B-site) will be investigated. A plethora of synthetic techniques including high-pressure synthesis in the GPa range will be employed to obtain the targeted phases. The physical properties of the synthesised materials will be investigated through a variety of cutting-edge characterisation techniques such as X-ray and neutron scattering, electron paramagnetic resonance, nuclear magnetic and muon spin resonance which will reveal important information on the nature of the magnetic interactions and dimensionality. The results of this project may provide new systems that exhibit quantum phenomena and thus help to expand the frontiers of quantum materials.
Benchtop nmr for lab-on-chip

Organ-on-a-chip (OOC) devices offer new approaches to metabolic disease modelling and drug discovery by providing biologically relevant models of tissues and organs in vitro integrated with sensing technology. As such, OOC devices have the potential to revolutionise the pharmaceutical industry by enabling reliable and high predictive in vitro testing of drug candidates. The capability to miniaturise microfluidic systems and advanced tissue fabrication procedures have enabled researchers to create multiple tissues on a chip with a high degree of control over experimental variables for high-content screening applications. The objective of this project is to develop a new technology based on magnetic resonance spectroscopy and imaging using dynamic nuclear polarisation (DNP-MR) integrated with OOC devices to monitor disease and evaluate drug response in OOC models. As a proof-of-concept, this project will fabricate a biomimetic multi OOC integrated device composed of liver spheroids and pancreatic islets and develop the necessary DNP-MR hardware and software to study metabolic diseases and for future drug screening applications.
Leading Practices for Strategic Asset Management: Strategic Asset Management, Communication, and Implementation

In response to the need identified by its utility members, the Water Environment Research Foundation funded a research program on Strategic Asset Management (SAM) Implementation and Communication for wastewater and water utilities to improve the management of their assets.

One objective of the research program included identifying the leading practices that contribute to a strategic asset management program. A self-assessment tool was developed and used by 36 utilities to identify the level of their asset management practice. These self-assessment scores were analyzed to identify potential leading practice utilities, as well as areas to focus as opportunities for improvement. The six areas of focus that were identified, included Organization and People, Strategic Asset Planning (and related Asset Management Plans), Business Risk Management, Maintenance, Secondary Data and Knowledge, and Accounting and Costing. The initial results were validated first by telephone interviews with the six leading practice utilities. Site visits were then conducted to research information on specific practices, as well as to collect multiple utility examples. Leading practice statements were developed, as well as a method whereby a utility's asset management team can identify candidate practices for adaption.

This title belongs to WERF Research Report Series .

ISBN: 9781780400198 (eBook)
Supporting high quality evaluation of covid-19 convalescent plasma throughoutt europe

Coronavirus disease 19 (COVID-19) is provoking the greatest global health crisis of this generation. With no vaccine or specific antiviral treatment available to date, the use of convalescent plasma (CP) from recovered COVID-19 patients has been considered a potential curative strategy. To demonstrate its efficacy and safety, clinical studies are ongoing or planned in various EU Member States. Unfortunately, there lacks a coordinated approach involving a large number of blood establishments (BEs) and clinical centres to harmonise protocols and guidelines, to standardise assays for characterising the potency of the plasma and to validate clinical outcome which will be of great importance to ensure that significant conclusions can be drawn. SUPPORT-E brings together major European BEs with world leading research capabilities with the aim to support high quality clinical and scientific evaluation of COVID-19 CP (CCP) and thereby achieve a consensus on the appropriate use of CCP in the treatment of COVID-19 across EU Member States. Hence, SUPPORT-E will advance the current state-of-the-art by delivering the much needed harmonised evidence-based recommendations with respect to the use of CPP in clinical trials and monitored access programmes for COVID-19 patients in Europe. Further, standardised informative in vitro assays providing scientific insights that could support such recommendations will also be developed. SUPPORT-E offers an EU-wide collaboration between Member States, BEs and clinical centres in order to close the knowledge gap and to ensure applicability of the recommendations for all EU Members States. SUPPORT-E represents the first European Union coordinated research effort on passive immunotherapy, sharing data and protocols in real-time and pooling efforts to decrease the time as much as possible for validating CCP as a valid therapeutic treatment and also providing a basis for further optimisation by combined approaches with other anti-viral treatments.
Audio Segmentation for speech recognition using feature extraction

Sound part removal assumes a vital half in programmed melody characterization. Highlight removal is that the center of substance primarily based depiction of sound records. With highlight removal from sound, a laptop has the capability understand the substance of slightly of melody while not the necessity of processed marks, for instance, craftsman, tune title or kind. This can be the elemental premise for data recovery assignments, for instance, comparison primarily based hunts, programmed arrangement interested in categories, or programmed association and grouping of melody chronicles. This archive clarifies the necessity for sound part removal framework, what is more depicts the foremost essential qualities, for instance, MFCC, ZCR, LPC , SNR , Spectrum Flux , Power Spectrum, RMS then forth quite twenty components. Also in this book different algorithms are studied for finding the above features and their performance is measured and evaluated and studied.