SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Developing multi-modality nanomedicines for targeted annotation of oncogenic signaling pathways

Spatial and temporal changes in the underlying biochemistry of cancer control disease progression and response/resistance to treatment. Developing methods to detect changes in oncogenic signaling at an early stage is vital to further our understanding of cancer, and will advance the next generation of anti-cancer therapies. Nanomedicine is the medical application of nanotechnology to diagnose or treat disease. In light of the recent introduction of tools like Positron Emission Tomography/Magnetic Resonance Imaging (PET/MRI) scanners, there is now a new opportunity to develop hybrid imaging protocols that can simultaneously take advantage of the functional and anatomic information available from PET/MRI to address changes in oncogenic signaling pathways. The work outlined in this interdisciplinary ERC Project is designed to advance new chemistry and imaging methods to measure changes in oncogenic signaling in various cancers before, during and after treatment using PET/MRI. The long-term goals are to expand the scope and utility of radiolabelled nanomedicines as dual-modality PET/MRI probes for detecting changes in oncogenic signaling in various cancers and develop efficient methods for translating new technologies to the clinic. Successful completion of this ERC Project has the potential to transform personalised clinical management of cancer patients via advanced PET/MRI detection of oncogenic signaling processes.
From potential to ability to compete: Towards a performance-based tourism competitiveness index

Abstract The purpose of this study is to design a ranking system for tourist destinations. The ranking system will be grounded in the competitiveness theory. The main tenet of the study reveals that the nexus inputs–outputs as entertained by several indices are not automatic. The study claims that a meaningful measurement of tourism competitiveness is performance. The study designs a tourism competitiveness index (TCI) derived from satisfaction, productivity and quality of life. The ranking in this study shows inconsistent results when compared to the World Economic Forum (WEF) tourism ranking. That is, the WEF tourism ranking revealed that countries at the top of the ranking are not necessarily strong in real tourism receipts per capita and quality of life; while the current study indicated that they actually are strong in those areas. The study further found that these two attributes (i.e. real receipts per capita and value added) strongly correlate with quality of life stressing the attributes of receipts per capita, value added and quality of life and their correlation as important elements in the descriptive theory building of tourism competitiveness.
Trends in incidence and severity of sports-related traumatic brain injury (TBI) in the emergency department, 2006–2011

To characterize and identify trends in sports-related traumatic brain injury (TBI) emergency department (ED) visits from 2006-2011.This study reviewed data on sports-related TBI among individuals under age 65 from the Nationwide Emergency Department Sample from 2006-2011. Visits were stratified by age, sex, injury severity, payer status and other criteria. Variations in incidence and severity were examined both between groups and over time. Odds of inpatient admission were calculated using regression modelling.Over the period examined, 489 572 sports-related TBI ED visits were reported. The majority (62.2%) of these visits occurred among males under the age of 18. The average head Abbreviated Injury Severity score among these individuals was 1.93 (95% CI = 1.93-1.94) and tended to be lowest among those in middle school and high school age groups; these were also less likely to be admitted. The absolute annual number of visits grew 65.9% from 2006 until 2011, with the majority of this growth occurring among children under age 15. Hospitalization rates dropped 35.6% over the same period.Changes in year-over-year presentation rates vs. hospitalization rates among young athletes suggest that players, coaches and parents may be more aware of sports-related TBI and have developed lower thresholds for seeking medical attention.
Levitated nanoparticles for technology and quantum nanophysics: new frontiers in physics at the nanoscale.

Technology is continuously miniaturizing. As it reaches the nanoscale we face unique challenges, such as managing thermal. From the other direction, advances in the quantum physics of a few atoms, ions, and solid-state qubits mean that we increasingly wish to scale up quantum systems, or interface them with nanoscale devices.

Opto- and electro-mechanical (NEMS and MEMS) devices have been controlled at the quantum level in recent years, an amazing advance allowing even entanglement between light and mechanical motion. However, all such systems are plagued by unavoidable environmental contact, and energy dissipation through strain, limiting the potential of mechanical devices to participate in both classical and quantum technologies.

By levitating the mechanical element, these problems are overcome. LEVITEQ will, for the first time, cool the motion and rotation of tailor-made silicon particles, enabling full quantum level control. This ultra-low dissipation system offers exquisite force sensitivity, by driving the rotation of a levitated nanorod. LEVITEQ will pioneer the control of nanoparticles by electronic circuits, allowing simple technological integration in a room temperature environment. This all-electrical system will challenge existing quartz crystal oscillator technology.

LEVITEQ will explore new regimes of physics, by working in extreme vacuum, elucidating thermodynamics on the nanoscale. This research will pave the way for a levitated quantum object acting as a node in a quantum network, for coherent signal storage and conversion.
The Effect of Physics in the Development of Indigenous Technology in Akwa Ibom State of Nigeria

This study was an attempt to determine empirically the effect of physics in the development of indigenous technology (production of local talking drum and canoe) in Akwa Ibom State. A total of 70 indigenous technologists (40 canoe makers and 30 talking drum makers) from Ikot Abasi, Essien Udim and Ikot Ekpene Local Government Areas of Akwa Ibom State randomly selected formed the sample for the study. One researcher-made instrument, Physics and Indigenous Technology Questionnaire (PITO) was used in gathering the data for the study. The reliability coefficient of the instrument was 0.86. Three hypotheses were stated to guide the investigation. The data generated in the study were analyzed using t-test at .05 significant level. The findings of the study showed that there is a significant effect of physics in the development of indigenous technology. Findings further revealed that Physics has a significant influence in the making of local talking drums and canoe.
The Reproductive Biology of Shirbot (Barbus grypus Heckel, 1843) in the Maroon River, Iran

Shirbot ( Barbus grypus ) is one of the species in south and southwest of Iran which is greatly favorable to residents of the region. Unfavorable ecological conditions in habitat of this species and overfishing have led to the reduction of the population of shirbot. Therefore, to restore the natural stock of this species, identifying its reproductive cycle associated with its habitat is of a great importance. In this study, the reproductive status of shirbot in the Maroon River in Khuzestan Province was studied in six sampling steps during four seasons. Also, morphological indicators, sex ratio, age of fish, gonadosomatic and hepatosomatic indices, histological changes in the testis and ovary of the fish were studied. The ratio of male fish to female was 2.35 to 1. The maximum value of gonadosomatic index (GSI) is among the specimens aged 3 to 5 years and in March and April. An increase of hepatosomatic index (HIS) during March may indicate the increased activity of liver during vitellogenesis and vitellogenin synthesis which is well verified by histological results of ovarian tissue. Based on our findings we recommend that the maximum reproductive activity of shirbot in the Maroon River starts around the end of March and continues to middle of July.
SEWING DEVICE

The invention relates to a sewing device (1) with a programmable electronic control system (4) for sewing pleats and darts. The aim of the invention is to abandon the need to change form-dependent parts (guiding tongue, pressure pad) when changing the sewing program. Guiding tongues dependent on the form of the seam and form-dependent pressure pads are thus discarded; the material to be sewn is simply fed by means of a folding tool (5) with a straight folding edge, and said material is fixed and guided during the sewing process by means of a rectilinear pressure pad (7). The electronic control system (4) is programmed in such a way that the desired seam is obtained exclusively by superpositioning longitudinal and transversal movements of the pressure pad (7).To achieve this, the parameters (1'-7<IV>) which determine the seam are preferably inputted using graphics.
Application of automated video analysis to road user behaviour

The successful planning, design and management of a traffic system is impossible without knowledge of how the traffic environment affects the behaviour of road users and how the behaviour is related to the main qualities of the traffic system (e.g. safety, efficiency). Automated video analysis is a promising tool for traffic behaviour research in that it enables collection of micro-level behaviour data for large populations of road users and provides a detailed description of their motion. This thesis describes the tests done with an automated video analysis system developed at Lund University. The system was used in two large scale studies with the main task of detecting the presence of road users of a particular type. Accuracy of position and speed estimates were tested in a study specially designed for that purpose. The thesis also elaborates on the problem of relating the behaviour of road users to safety and proposes organising all the elementary events in traffic (defined here as encounters between two road users) into a severity hierarchy. The process of an encounter is described with a set of continuous safety indicators that can handle the various approach angles and transfer between being and not being on a collision course. When an objective measure for an encounter severity is found, the severity hierarchies may be used not only for describing safety but also for studying the balance between safety and other qualities valued by road users.
Online Detection of Selenium and Its Retention in Reducing Gasification Atmosphere

The emission of selenium from coal gasification processes can cause harm to the environment and downstream equipment. With upcoming legislation, reliable detection as well as control of such gas species become crucial. This study therefore addresses the development and successful employment of an online analytical method, based on the direct introduction of a simplified flue gas (H2, H2O, H2Se, Ar) into an ICP-MS. In combination with matrix matched calibration, the calculated and verified detection limits of H2Se lie below 1 ppbv, thus being comparable to current offline methods. These low detection limits and the high temporal resolution (>1 Hz) enable the use of this method as a quick and robust tool for the lab- and bench-scale performance evaluation of sorbent materials. As a case study, Zn/Al2O3 was tested toward H2Se capturing at warm temperatures (150–350 °C). The results show that both, the support and the active phase, interact with the contaminant. While γ-Al2O3 can retain H2Se at dry reaction c...
Comparison of protective effects of L-carnitine and amifostine on radiation-induced toxicity to growing bone: histopathology and scintigraphy findings.

The aim of the present study was to evaluate the radioprotective efficacy of L-carnitine (LC) in growing bones in comparison to amifostine.Sixty two-week-old Wistar albino rats were randomly assigned to six equal groups: Group 1, control (CONT); Group 2, irradiation alone (RT); Group 3, amifostine plus irradiation (AMI+ RT); Group 4, L-carnitine plus irradiation (LC+ RT); Group 5, amifostine alone (AMI); Group 6, L-carnitine alone (LC). The rats in the AMI+ RT, LC+ RT and RT groups were irradiated individually with a single dose of 20 Gy to the left femur. LC (300 mg/kg) and amifostine (200 mg/kg) were applied 30 min before irradiation. The animals were scanned for bone area, mineral content and bone mineral density (BMD) by DEXA and the 99mTc methylene diphosphonate uptake ratio (MUR) was calculated by bone scintigraphy. Histopathological analysis of bone and cartilage was also carried out after euthanasia.Pretreatment with LC or amifostine reduced the radiation-induced damage in growing bone (p= 0.007 and p= 0.04 respectively) and in the epiphysial cartilage (p= 0.002 and p= 0.015 respectively). The protective effect of LC was similar to that of amifostine on both growing bone and on the epiphysial cartilage. The mean left-femur BMD values were significantly higher in the LC+RT (p= 0.02) and AMI+RT (p= 0.01) groups than in the RT group. but did not differ with the two protective agents. Pretreatment with AMI (p= 0.002) and LC (p= 0.01) improved the MUR.L-carnitine is equally as effective as amifostine at protecting growing bone against single dose irradiation damage.
Enabling chemical propulsion system for the growing small satellite market

NanoAvionics is developing novel small satellite (below 150 kg) market oriented product – green chemical propulsion system which is innovative, as it makes use of an environmentally friendly propellant, and is a low cost integral plug and play design offering great economic advantages to the growing small satellite market, which presently suffers from the availability of a low cost high performance propulsion solution.  
High performance propulsion systems are one of the technologies required by small satellites in order to allow them to fulfill their full market potential enabling small satellites to be as capable as those well above 150 kg.
This feasibility study will help to determine and set the targets for the final shape of the product according to the requirements of the target customer groups as TRL-6 (current maturity level of the product) is a crucial point at which extensive product design decisions must be undertaken and finalized.
This feasibility study will perform the following tasks: 
1. Identify the market potential of the proposed propulsion system;
2. Determine the level of customer demand and market interest in the product; 
3. Develop a technology IPR strategy, and develop a solid business model for development of the product within the company.  The business model will include a sales strategy and a plan for productionizzation of the design and subsequent manufacturing. 
This project will result detailed feasibility report, including a business plan which will summarize small satellite propulsion system market research, IPR strategy, business model including sales strategy, and consideration of strategic partnerships for production and manufacturing operations.
NanoAvionics plans to carry out this feasibility study and prepare an elaborated business plan during the 6 months period.
Reliable energy and cost efficient traction system for railway

Rail is a fundamental service for modern societies and the backbone of a sustainable transport system. To meet the numerous challenges ahead, the global rail sector must increasingly rely on the emerging disruptive technologies such as advanced robotics, 3-D printing, high computing power and connectivity, etc. which are integrated with analytical and cognitive technologies that enable machine-to-machine and machine-to-human communication.On top comes the pressure to reduce energy consumption, pollution and the consumption of other resources. Mastering the breakthrough developments of new technologies is of capital importance for the railway industry to deliver smart and efficient solutions.Indeed, essential to the growth of the rail industry is the reduction of the overall life cycle exploitation costs of all rail sub-systems. The Traction Drive sub-system is one of the main sub-systems of a train as it moves the train converting energy from an electrical source (directly or via a chemical source) into a mechanical one. RECET4Rail will focus on the following new technologies for the Traction Drive sub-system: development of design approaches, end-to-end conception time evaluation and feasibility/performance study of 3D printing technologies for new traction’s components use cases; Dynamic Wireless Power Transfer system sizing for actual city profiles focused on opportunistic charging; improving the understanding of the robustness and reliability of high voltage SiC modules; and development of smart maintenance approaches enabled by predictive analytics, trained on big data. RECET4Rail will provide essential knowledge that will lead to future improvement of the high TRL level S2R traction demonstrations on trains done by the S2R Members, preparing also future S2R key work on domains like digitalisation applied to Traction, environmental sustainability (especially devising carbon free traction systems) or reinforcement of standardisation to lower complexity and costs
‘Generic Misery Music’? Emo and the Problem of Contemporary Youth Culture

This article examines the Australian newspaper coverage of the Emo youth cultural movement in relation to two incidents that contributed to its growing inclusion in mainstream media discourse: the February 2007 murder of 15-year-old Carly Ryan and the April 2007 suicides of 16-year-old friends Jodie Gater and Stephanie Gestier. The deaths of the three young women were frequently linked to their apparent involvement in the Emo movement, which was described as a dangerous and worrying development in youth culture. However, specific concerns about Emo were frequently subsumed into broader anxieties about young people more generally, particularly in relation to concerns associated with self-harm, unsupervised internet use and school bullying. The disinclination among participants of this movements to identify as Emo or to challenge the media's framing of Emo culture has contributed much to the media's redefinition of Emo as a characteristic of ‘kids today’ rather than a specific subcultural affiliation.
Public debt: risk management and restructuring optimization

Much we have been learning about the flawed design of eurozone form the current crisis. Non-optimality of euro as a 
currency zone, banking system fragmentation, weak institutional structures, insufficient political integration, lagging 
competitiveness and global imbalances, are all blamed for the crisis. At a country level problems are attributed, according to The World Bank and IMF, imprudent public debt management, weak macroeconomic management, and debt overhang. 

Our project looks into these over-arching challenges with the broad objective to: ""Develop the capacity for risk management of public debt that can be used in response to crises, and to analyze policy  proposals for debt restructuring and common assumption of debt in a currency union"". The eurozone crisis challenges us to develop our capabilities for public debt management and advance the state-of-the-art.This is the purpose of the project. 
The four specific research tasks, taken together, advance the broad objective: 
1. Develop an asset-and-liability management framework for risk management of public debt. 
2. Operationalize the framework using multi-period stochastic programming integrated with multi-factor simulations. 
3. Extend the optimization model to incorporate debt sustainability analysis and study debt restructuring of crisis countries.
4. Extend the simulation models to integrate current proposals for EU-bonds in public debt risk management. 
The project is devoted to complementing existing skills and broadening the fellow's knowledge base to develop models for 
asset-liability management optimization and EU-bond pricing, implement and calibrate them using market data, and 
demonstrate their efficacy in addressing policy issues for public debt management  in crisis countries. The models will 
be tested in depth on the interesting case of Cyprus, for which we have special knowledge and data, on IMF stylized examples, and for the Italian and Argentinean debt where we also have access.
Cultural Heritage as a Source of Societal Well-being in European Regions

During the European Year of Cultural Heritage 2018, over 23 000 events were organised, reaching more than 12. 8 million participants. This clearly shows the potential impact that cultural heritage can have on economic development and people’s quality of life.

During the last decade, policymakers have increasingly acknowledged the role of cultural heritage as a strategic resource for economic growth, employment and territorial cohesion. This is reflected in several European policy documents, more recently the “New European Agenda for Culture”, adopted by the European Commission in May 2018, and the “European Heritage Strategy for the 21st Century”, adopted by the Council of Europe in April 2017. 

Cultural heritage has been gradually streamlined in different policy areas, such as the EU Cohesion policy, thus showing the growing strategic importance that the topic has gained on the European agenda. Several initiatives at the European level contribute to the general appraisal of cultural heritage, such as the European Heritage Days, the European Heritage Label, the European Heritage Awards and the European Capitals of Culture. Despite recent efforts to improve cultural heritage statistics by the European Commission, it is still a challenge to fully capture the significance of its impact on the economy and society.

On 7 December 2018, the European Commission presented the European Framework for Action on Cultural Heritage which among other things calls for evidence-based decision-making in the cultural heritage field and enumerates a number of projects that are going to be carried out in order to address the issue of measuring the impact of culture and cultural heritage on economy, society and local development. The Framework mentions that ESPON’s study “Cultural Heritage as a Source of Societal Well-being in European Regions” (2020–2022) will play an important role in providing evidence and data on the impact of cultural heritage on societal well-being.

The objective of this research is to develop a pan-European methodology and territorial analysis on the impacts of cultural heritage on society, considering well-being, social inclusion and other aspects. The research shall cover both material and intangible cultural heritage and the impact should be associated with:
-	Presence of material cultural heritage (stock of buildings and other objects).
-	Consumption and use of cultural heritage.
-	Digitalization of cultural heritage.
-	EU funded investments in cultural heritage.
-	Activities (policies) aimed at increasing the positive impact of cultural heritage and diminishing the negative impact.