SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Functional connectomics of the amygdala in social interactions of different valence

Understanding how brain controls social interactions is one of the central goals of neuroscience. Whereas social interactions and their effects on the emotional state of an individual are relatively well described at the behavioral level, much less is known about neural mechanisms involved in these very complex phenomena, especially in the amygdala, a key structure processing emotions in the brain.
Recent investigations, mainly on fear learning and extinction, have shown that there are highly specialized neuronal circuits within the amygdala that control specific behaviors. However, a high density of interconnections, both among amygdalar nuclei and between amygdalar nuclei and other brain regions, and the lack of a predictable distribution of functional cell types make defining behavioral functions of the amygdalar neuronal circuits challenging. Therefore, to understand how different neuronal circuits in the amygdala produce different behaviors tracing anatomical connections between activated neurons, i.e., the functional anatomy is needed. 
Published data and our preliminary results suggest that within the amygdala there exist different neuronal circuits mediating social interactions of different valence (positive or negative affective significance) and that circuits controlling social and non-social emotions differ. Combining our recently developed behavioral models of adult, non-aggressive, same-sex social interactions with the methods of tracing anatomical connections between activated neurons, we plan to identify neural circuitry underlying social interactions of different emotional valence. This goal will be achieved by: (1) Characterizing functional anatomy of neuronal circuits in the amygdala underlying socially transferred emotions; (2) Examining role of the identified neuronal subpopulations in control of social behaviors; (3) Verifying role of matrix metalloproteinase-9-dependent neuronal subpopulations within the amygdala in social motivation.
Energy-Efficient heterogeneous computing at exascale

In order to reach exascale performance current HPC servers need to be improved. Simple scaling is not a feasible solution due to the increasing utility costs and power consumption limitations. Apart from improvements in implementation technology, what is needed is to refine the HPC application development as well as the  architecture of the future HPC systems.

ECOSCALE tackles this challenge by proposing a scalable programming environment and hardware architecture tailored to the characteristics and trends of current and future HPC applications, reducing significantly the data traffic as well as the energy consumption and delays. We first propose a novel heterogeneous energy-efficient hierarchical architecture and a hybrid MPI+OpenCL programming environment and runtime system. The proposed architecture, programming model and runtime system follows a hierarchical approach where the system is partitioned into multiple autonomous Workers (i.e. compute nodes). Workers are interconnected in a tree-like structure in order to form larger Partitioned  Global Address Space (PGAS) partitions, which are further hierarchically interconnected via an MPI protocol. 

Secondly, to further increase the energy efficiency of the system as well as its resilience, the Workers will employ reconfigurable accelerators that can perform coherent memory accesses in the virtual address space utilizing an IOMMU. The ECOSCALE architecture will support shared partitioned reconfigurable resources accessed by any Worker in a PGAS partition, and, more importantly, automated hardware synthesis of these resources from an OpenCL-based programming model.

We follow a co-design approach that spans a scalable HPC hardware platform, a middleware layer, a programming and a runtime environment as well as a high-level design environment for mapping applications onto the system. A proof of concept prototype and a simulator will be built in order to run two real-world HPC applications and several benchmarks.
Combining ct scanning and spectroscopy to characterise micro-plastics, a growing threat to seabirds and other marine animals

Plastic debris is now a major source of anthropogenic pollution with >5 trillion fragments of micro-plastic in the world's oceans, and can lead to deleterious and often fatal consequences when ingested by seabirds and other marine animals, including hormonal disruption, chemical toxicity, or obstruction of digestive tract. In this action we propose to develop a standard method for characterisation of plastic fragments in the environment, using a combination of micro-CT scanning and FTIR, Raman spectroscopy to measure both physical parameters (size, shape, surface area) and chemical properties (primary polymers, additives, etc.) of individual fragments. We intend to apply the developed methodology to an existing collection of >10,000 plastic fragments extracted from living and dead seabirds over 10 years, and identify which properties of ingested plastics are associated with the greatest negative impact on seabird physiology and health outcomes. Analysis of preserved seabirds from spirit collections will provide historical context for the onset and rise of plastic contamination in seabirds over recent decades. The effect of environmental aging on plastics will be investigated by laboratory studies of several industrial polymers that comprise a major fraction of marine plastic pollution, identifying the spectroscopic signature of photo-chemical degradation under ambient marine conditions and in the acidic environment of seabird stomachs. With the increasingly ubiquitous presence of plastic debris in the environment, it is more important than ever that we understand the precise mechanisms by which that debris negatively impacts marine life so that we may mitigate those effects.
Consolidação da infraestrutura de TI da empresa ArbriivPro

O principal objetivo deste projeto é adquirir um centro de dados moderno para reforçar a capacidade dos servidores através do aumento do volume de negócios. A realização bem sucedida do projeto contribuirá para o reforço dos negócios básicos, o que constitui um pré-requisito para o desenvolvimento dos existentes e para a implementação de novas soluções de utilizador. A renovação da infraestrutura de TI visa fazer negócios em uma base diária mais eficiente com um armazenamento de dados mais seguro. Como resultado do projeto, espera-se que o projeto expanda as soluções do utente, aumente a receita de vendas e aumente o emprego.
SURFACES OF PLASTIC GLAZING OF TAILGATES

A plastic glazing of a tailgate of a vehicle is provided, the plastic glazing comprising: a translucent component, wherein a portion of the translucent component forms a rear window of the vehicle; a non-transparent component molded onto the translucent component, wherein an overlapping portion of the translucent component and the non-transparent component forms a blackout region proximate to the rear window, wherein the plastic glazing is of one-piece molded plastic construction, wherein the translucent component comprises a first textured surface in a region adjacent to the blackout region, where the first textured surface is configured to conceal a component of the vehicle.
Advanced programming environments for exascale data-centric computing

Power efficiency has emerged as the primary design constraint for the next generation of computing systems and the dominant source of energy consumption has shifted from computing elements to the movement of data. This shift will make locality of data the new programming challenge of the decade. However, current programming environments take a compute-centric approach and do not reflect the realities of the architectural trends.  For performance and energy efficiency reasons, there is a critical need for a new data-centric programming paradigm that takes data locality as a primary criterion. Moreover the next generation of high performance systems (Exascale Systems) will be equipped with 2048-core chips, requiring applications to expose over a thousand-way concurrency. For a smooth transition to these advanced technologies, this project proposes a theoretical foundation and programming abstractions; embodied in an API (Application Programming Interface) that provides a rich interface to address the dual challenges of data locality and increased on-chip parallelism for emerging parallel computing systems. The ultimate goal of the project is to integrate the proposed API into real-life applications that are of great interest to Europe. The project will study Turbulent Combustion as a motivating application class because of its importance in energy production. The proposed research, by reinventing the programming environment to better reflect the realities of future platforms, will facilitate the transition to Exascale of applications that are critical for strengthening European leadership in HPC.
A new edition and commentary on the pseudo-virgilian dirae

DIRAE is an action designed to explore the Dirae, a largely neglected anonymous Latin poem, probably from the first century B.C. Transmitted as part of the so-called Appendix Vergiliana, it is among the most corrupt Latin poetic texts surviving from antiquity. Being anonymous and of uncertain date of composition (in fact, it may consist of two separate poems, possibly by different authors), the poem lacks secure links to a specific context of production. DIRAE aims to bring the Dirae within the orbit of current classical scholarship by creating a set of fundamental and innovative research tools: a comprehensive philological and literary commentary, and an open-access digital critical edition. The core objective of the action is to reconstruct the poem’s text by employing a wide range of research measures, from fresh inspection of all primary sources and thorough use of earlier textual scholarship to conjectural emendation. In addition to solving textual issues, the commentary will explore the Dirae’s complex intertextuality with other poetry, both Latin and Greek. A minute analysis of linguistic, metrical and literary features will aim to establish the poem’s context of composition, to answer the question of unity (if not authorship), and to uncover its implicit poetic programme. DIRAE’s research outputs will include the publication of a commentary in monograph form and the creation of an open- access web resource hosting a digital edition of the poem accompanied by a comprehensive repertory of conjectures and a collection of digital images of all primary manuscripts. While the commentary can be expected to become the standard reference work for all subsequent research on the Dirae, the impact of the digital edition will potentially be even wider: being one of the first of its kind, it can serve as a model for future digital critical editions of classical authors.
Características mineralógicas e aplicações do minério de ferro oriundo da província mineral de Carajás: uma revisão

O minério de ferro é essencial para a obtenção dos aços, os quais são materiais amplamente utilizados em nossa sociedade. No Brasil as principais reservas mineralógicas associadas aos depósitos de ferro estão localizadas na província mineral de Carajás, situada no estado do Pará. Este estudo apresenta para o minério obtido na província de Carajás, uma revisão de suas características gerais como: ocorrência, alteração, composição, propriedades físicas e aplicações. Por meio de dados da literatura foi observado que a hematita, magnetita e goethita estão presentes no minério de ferro encontrado na província de Carajás. Diante do exposto, esta investigação exibe informações úteis com potencial benefício para o setor mineral e industrial.
Culture and riskmanagement in man-made and natural disasters

As risks are not “objective” but socially and culturally constructed, disaster management which is aware, respects, and makes use of local cultural aspects will be not only more effective but, at the same time, also improve the community’s disaster coping capacities. CARISMAND is setting out to identify these factors, to explore existing gaps and opportunities for improvement of disaster policies and procedures, and to develop a comprehensive toolkit which will allow professional as well as voluntary disaster managers to adopt culturally-aware everyday practices. This goal will be achieved by approaching the links, and gaps, between disaster management, culture and risk perception from the broadest possible multi-disciplinary perspective and, simultaneously, developing a feedback-loop between disaster management stakeholders and citizens to establish, test, and refine proposed solutions for culturally-informed best practices in disaster management. Whilst experts from a variety of fields (in particular legal, IT, cognitive science, anthropology, psychology, sociology) will undertake a comprehensive collation of existing knowledge and structures, a number of Citizen Summits and Stakeholder Assemblies will be organised. Systematically, CARISMAND will use an approach that examines natural, man-made and technical disasters, placing at the centre of attention specific aspects that affect culturally informed risk perceptions, eg whether disasters are caused intentionally or not, the different “visibility” of hazards, and various time scales of disasters such as slow/fast onset and short- and long-term effects. By organising six Citizen Summits (two per disaster category per year in two separate locations) where such disaster risks are prevalent , and three Stakeholder Assemblies (one per year) where the results are discussed through a wide cross-sectional knowledge transfer between disaster managers from different locations as well as from different cultural backgrounds.
Separable rotary table

The invention relates to a rotary table (1) for positioning a workpiece by means of a manual drive (4a, 4b), said rotary table comprising a base plate (2) having a base plate-side transmission device (20), and also comprising a bearing plate (3), mounted rotatably on the base plate and having a bearing plate-side transmission device (30), which is configured to rotate the bearing plate (3) relative to the base plate (2) by means of a drive (4), wherein the base plate (2) is formed as a two-part or multi-part component composed of at least two plate segments (2a, 2b), and wherein the bearing plate (3) is formed as a two-part or multi-part component composed of at least two plate segments (3a, 3b).
HERSTELLUNG EINES HOLZHAUSES UND EINER HOLZDUSCHE, SLOWENIEN UND DER EU

Die Operation umfasst die Herstellung eines Holzhauses und einer Holzdusche, die das Ergebnis seiner eigenen Entwicklung sein wird.
Lights in lincoln – get hold of tech and science research nights

The key aim of University of Lincoln (UoL) ‘LI-GHTS’ festival is making research accessible for everyone, expressed in its LIGHTS acroynm (Lincoln – Get Hold of Tech and Science). LIGHTS Nights will serve a huge hinterland of the Midlands and North/North Eastern England with a dispersed, predominantly rural population including some of the most deprived areas of the UK which are home to large numbers of non-UK born EU citizens. Centred in this area, which too often lags behind other parts of Europe socially, economically and educationally, LIGHTS Nights has immense capacity to help realise the untapped potential of its local and regional hinterland by bringing people of all ages and backgrounds closer to the research of UoL through showcasing some of the University’s most exciting and dynamic science, informing them of the amazing science being forged on their doorstep, and inspiring them with the importance, excitement and excellent of our research.
The UoL sits in the ancient Roman and medieval city of Lincoln, close to the stunning cathedral which has dominated the surrounding landscape for nearly 1,000 years.  In contrast, the UoL was founded barely 20 years ago, but has become the UK’s fastest growing university expanding from nothing in 1995 to more than 13,000 students in 2015 and been ranked among the top 40 UK universities. The UoL’s meteoric growth has not been allowed to sever the it’s connections with its community. As well as working internationally, UoL is firmly embedded within its locale and is thus transforming its host city.  The ambitious and upward trajectory of the UoL represents an inspiring model for young people looking to engage with learning and research.  As such the opportunity to stage a Researcher’s Night is both timely and very valuable, and has a high potential to deliver a significant dividend in terms of attitudinal shift in wider publics towards the importance and benefits of research and research as a career.
A cutfem paradigm for surgical guided growth of bone joints

Many children suffer from bone deformities, which severely hinders their ability to walk. Some children may require invasive surgical treatment, such as cutting their bones, whilst others may recover their mobility through less invasive treatments such as guided growth surgery. However, surgeons have difficulties choosing the best treatment options because there is no reliable tool to help them predict the post-operative evolution of bone joints. CutGrow aims to provide a numerical platform whereby bone growth will be predicted virtually. The platform will rely on a novel finite element technology, CutFEM, developed by the applicant, Dr. Claus, which circumvents the need for meshing complex geometries. This algorithmic concept will bestow numerical agility upon all steps of the simulation process, from acquiring patient-specific data to handling complex contact conditions between interacting bones, the latter being the domain of excellence of the host supervisor Prof. Erleben. In the first stage of CutGrow, a seamless and robust simulation pipeline in the specific context of bone joint mechanics and growth will be created. In a second stage, the simulation will be used as a basis to develop a unifying and highly versatile model for children’s bone growth, capable of easily handling a range of mathematical growth stimulus theories. Finally, we will specialize the developments to the context of guided bone growth and prove that the proposed modelling framework can reproduce clinical data gathered by MD Wong at Hvidovre Hospital. The CutGrow simulation environment has the potential to transform paediatric orthopaedic surgery, by providing researchers with an agile tool to investigate new treatment options virtually and to design new operation planning procedures based on reliable, physics based simulation technologies.
A new generation of microbial expression hosts and tools for the production of biotherapeutics and high-value enzymes

The ‘SECRETERS’ partnership aims to bring about a step change in the production of recombinant proteins, particularly Biotherapeutics and Industrial Enzymes. Both are critical products for the EU biotechnology sector, with combined markets in excess of $140 billion p.a.; the former are essential for the treatment of major diseases whereas the latter permeate every aspect of our daily life. Many proteins in these categories pose severe problems in production, especially disulphide-bonded proteins and new format 'difficult-to-express' proteins. SECRETERS will train a team of 15 ESRs to develop a new generation of super-producing microbial production hosts, including Escherichia coli, Bacillus species and the yeast Pichia pastoris. The project capitalises on a series of recent innovations and involves close collaboration between 5 academic Beneficiaries, who provide world-leading expertise in redox chemistry, synthetic biology and protein expression, and 5 non-academic Beneficiaries, who include some of the world's premier biotherapeutic and industrial enzyme companies. It will enable the biotherapeutics industry to produce challenging medicines at lower costs, resulting in new drugs and wider patient access, and allow the enzymes industry to deliver a range of powerful new products. SECRETERS will equip ESRs with the interdisciplinary and intersectoral skills required to thrive in these industries, with quality assurance systems embedded throughout the programme and a commitment to a wide-ranging dissemination/outreach programme. Based on a responsible innovation approach, with clear foci on research and entrepreneurial training, SECRETERS will deliver a team of superbly-trained scientists, poised to engage in some of Europe's most important biotechnology sectors.
TACHOMETER FOR DOWNHOLE DRILLING MOTOR

A tachometer for a downhole motor includes: a tubular housing having a coupling for connection to a housing of the motor; and a probe. The probe: has a coupling for connection to a rotor of the motor, is movable relative to the tachometer housing, and has at least a portion disposed in a bore of the tachometer housing. The tachometer further includes electronics disposed in the tachometer housing and including: a battery; one or more proximity sensors for tracking an orbit of the probe; and a programmable logic controller (PLC). The PLC is operable: to receive the tracked orbit, and at least one of: to determine an angular speed of the probe using the tracked orbit, and to forecast a remaining lifespan of the motor using the tracked orbit.
ASSAY AND PROCESS FOR THE DETECTION OF HPV ANTIBODIES

The invention relates to an assay and a process for the detection of HPV type-specific antibodies. In particular, the invention relates to an assay, comprising a substrate coated with a negatively charged macromolecule and at least one HPV type-restricted epitope, and a process for the detection of HPV antibodies using the assay of the invention.
AN OLIGOSACCHARIDE-ENRICHED COMPOSITION HAVING IMMUNE-MODULATORY AND ANTI-ADHESION PROPERTIES

This invention provides an oligosaccharide-enriched composition that is derived from a bovine milk whey fraction and comprises at least 23% oligosaccharides (at least 30g per 100g of composition dry weight) having a molecular weight range of 300-1200Da, and at least 20% sialyllactose (at least 20g per 100g of composition dry weight). The oligosaccharide-enriched composition has been found to have a significant immunomodulatory effect (Fig. 1) and has been shown to significantly reduce adhesion of pathogenic bacteria to lung cells and activated pharynx cells, and thereby have a protective effect in humans from respiratory and gastrointestinal infections (Figs 3 and 4). The composition of the invention is derived from a dairy product stream that is substantially free of casein and retains lactose and oligosaccharides, for example demineralised whey powder, demineralised whey, whey permeate, or mother liquor. The dairy product stream is subjected to a micro filtration step to remove whey protein and bacteria, the permeate is then subjected to an ultrafiltration step to enrich for oligosaccharides, and the permeate from the ultrafiltration step is enriched in oligosaccharides having a molecular weight of 300-1200Da, using a chromatographic step.