SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Smart restoration with particle infused repointing

The objective of the proposed project is the development of a damage sensing material for application in structures of architectural heritage. This material comprises lime mortar infused with conductive carbon nano-particles, applicable for repair and strengthening of historic masonry buildings through repointing of mortar joints.

The proposed material is envisaged as possessing improved strength and ductility, which are critical in enhancing the durability of existing buildings. It relies on the electrical conductivity of the nano-particles for the detection of damage and the measurement of deformation in masonry structural elements.

The project begins with the optimisation of a nano-particle infused lime mortar mix. Subsequently, the characterization of the enhancement of the mechanical properties of the material is performed. This is followed by the development of a quantitative damage and deformation measurement protocol. The project is concluded by the testing of the material in full scale structural members. Through the up-scaling of novel materials and self-sensing technology, it encompasses a lab to industry transition.

In addition to being a cost-effective means of structural damage monitoring, the material is expected to moderately enhance the structural behaviour of masonry members, while adhering to the principles of intervention on historic structures. In light of the danger to the integrity and durability of historic buildings due to the peaking of induced earthquake and the increase of ground movement in European urban centres, the project is deemed timely and potentially deeply impactful.

The project is expected to greatly enhance the researcher's prospects for an academic career, in addition to sharpening his technical and research grant proposal writing skills. Further, it is expected to provide, in the long term, an excellent contribution to research, innovation potential, industry and society.
Localization in biomechanics and mechanobiology of aneurysms: towards personalized medicine

Rupture of Aortic Aneurysms (AA), which kills more than 30 000 persons every year in Europe and the USA, is a complex phenomenon that occurs when the wall stress exceeds the local strength of the aorta due to degraded properties of the tissue. The state of the art in AA biomechanics and mechanobiology reveals that major scientific challenges still have to be addressed to permit patient-specific computational predictions of AA rupture and enable localized repair of the structure with targeted pharmacologic treatment. A first challenge relates to ensuring an objective prediction of localized mechanisms preceding rupture. A second challenge relates to modelling the patient-specific evolutions of material properties leading to the localized mechanisms preceding rupture. Addressing these challenges is the aim of the BIOLOCHANICS proposal. We will take into account internal length-scales controlling localization mechanisms preceding AA rupture by implementing an enriched, also named nonlocal, continuum damage theory in the computational models of AA biomechanics and mechanobiology. We will also develop very advanced experiments, based on full-field optical measurements, aimed at characterizing localization mechanisms occurring in aortic tissues and at identifying local distributions of material properties at different stages of AA progression. A first in vivo application will be performed on genetic and pharmacological models of mice and rat AA. Eventually, a retrospective clinical study involving more than 100 patients at the Saint-Etienne University hospital will permit calibrating estimations of AA rupture risk thanks to our novel approaches and infuse them into future clinical practice. Through the achievements of BIOLOCHANICS, nonlocal mechanics will be possibly extended to other soft tissues for applications in orthopaedics, oncology, sport biomechanics, interventional surgery, human safety, cell biology, etc.
Evolutionary Meta-Analysis of Association Studies Reveals Ancient Constraints Affecting Disease Marker Discovery

Genome-wide disease association studies contrast genetic variation between disease cohorts and healthy populations to discover single nucleotide polymorphisms (SNPs) and other genetic markers revealing underlying genetic architectures of human diseases. Despite scores of efforts over the past decade, many reproducible genetic variants that explain substantial proportions of the heritable risk of common human diseases remain undiscovered. We have conducted a multispecies genomic analysis of 5,831 putative human risk variants for more than 230 disease phenotypes reported in 2,021 studies. We find that the current approaches show a propensity for discovering disease-associated SNPs (dSNPs) at conserved genomic positions because the effect size (odds ratio) and allelic P value of genetic association of an SNP relates strongly to the evolutionary conservation of their genomic position. We propose a new measure for ranking SNPs that integrates evolutionary conservation scores and the P value (E-rank). Using published data from a large case-control study, we demonstrate that E-rank method prioritizes SNPs with a greater likelihood of bona fide and reproducible genetic disease associations, many of which may explain greater proportions of genetic variance. Therefore, long-term evolutionary histories of genomic positions offer key practical utility in reassessing data from existing disease association studies, and in the design and analysis of future studies aimed at revealing the genetic basis of common human diseases.
Modeling unimolecular reactions in photoelectron photoion coincidence experiments

A computer program has been developed to model and analyze the data from photoelectron photoion coincidence (PEPICO) spectroscopy experiments. This code has been used during the past 12 years to extract thermochemical and kinetics information for almost a hundred systems, and the results have been published in over forty papers. It models the dissociative photoionization process in the threshold PEPICO experiment by calculating the thermal energy distribution of the neutral molecule, the energy distribution of the molecular ion as a function of the photon energy, and the resolution of the experiment. Parallel or consecutive dissociation paths of the molecular ion and also of the resulting fragment ions are modeled to reproduce the experimental breakdown curves and time-of-flight distributions. The latter are used to extract the experimental dissociation rates. For slow dissociations, either the quasi-exponential fragment peak shapes or, when the mass resolution is insufficient to model the peak shapes explicitly, the center of mass of the peaks can be used to obtain the rate constants. The internal energy distribution of the fragment ions is calculated from the densities of states using the microcanonical formalism to describe consecutive dissociations. Dissociation rates can be calculated by the RRKM, SSACM or VTST rate theories, and can include tunneling effects, as well. Isomerization of the dissociating ions can also be considered using analytical formulae for the dissociation rates either from the original or the isomer ions. The program can optimize the various input parameters to find a good fit to the experimental data, using the downhill simplex algorithm.
Giardia intestinalis: effects of Pulsatilla chinensis extracts on trophozoites

Pulsatilla chinensis is a medicinal root plant that has been used to treat a wide range of disease conditions. Our study determined the antiprotozoal activity of various P. chinensis extracts and fractions against Giardia intestinalis including their effects on parasite growth, cell viability, adherence, and morphology. Ethyl acetate extracts (IC50 = 257.081 μg/ml) were the most active to inhibit the growth of G. intestinalis followed by aqueous extract (PWE), saponins, and n-butanol extract. The PWE and ethyl acetate extract inhibited G. intestinalis trophozoites adherence after 3 h of incubation and killed almost 50 % of the parasite population in a time-dependent manner. Changes in morphology, presence of precipitates in the cytoplasm, dissolved cytoplasm with large vacuole, break of flagella and ventral disk, membrane blebs, and intracellular and nuclear clearance of the treated trophozoites were observed by scanning and transmission electron microscopy. We demonstrated that P. chinensis induced these changes in G. intestinalis morphology and consequently has potential therapeutic use against giardiasis.
Who Receives Food Stamps During Adulthood? Analyzing Repeatable Events With Incomplete Event Histories

Abstract Using data from the Panel Study of Income Dynamics (PSID) from 1968 to 2005, we estimate the cumulative probability that young adults in the United States will receive food stamps during adulthood, and examine how that probability varies with an individual’s income and education at age 25 as well as by race and gender. We find that the probability of first food stamp receipt as an adult declines sharply with age, indicating that most adult recipients do so by age 40. Also, those receiving food stamps in early adulthood are likely to receive them again. For these reasons, and because food stamp receipt is a repeatable event, life table analyses that include individuals who are not observed until after they become exposed to the risk of food stamp receipt (whom we label “late entrants”) are likely to overstate cumulative participation during adulthood. For example, one often-cited study included individuals who enter their sample after age 20 (late entrants) and report that 50.8% of 20-year-olds are recipients by age 65. In contrast, when we exclude late entrants, we find that 39.2% of 20-year-olds and 29.7% of 25-year-olds receive benefits during adulthood.
Development of a high-performance digital imprinting device and chemical markers to verify the authenticity of the reflective film used in the production of license plates

Number_reference_aid_programme: SA.41471(2015/X) Purpose of public aid: art: 25 EC Regulation No 651/2014 of 17 June 2014 declaring certain categories of aid compatible with the internal market in the application of Articles 107 and 108 of the Treaty (OJ L 119, p. That’s it. EU L 187/1 of 26.06.2014). The subject of the project is to carry out research and development works that will enable the development of a prototype of a digital device for imprinting and chemical markers to verify the authenticity of the reflective film used in the production of registration plates (process innovation) and the boards with print containing a chemical marker (product innovation). License plates, in which a reflective film with print and marker will be used, will be plates whose falsification will be much more difficult. In addition to many other safety elements currently used by the Applicant in the production of license plates, the safety elements in the form of chemical markers will allow identification by quick and simple verification of the effect of the excitation caused by the illumination of the imprint with a marker using a laser radiation source, but also product identification through the use of appropriate detectors, which will verify the unique and unique spectrum with the characteristics that are compared with the recorded pattern. The compatibility of the standard with the signal received will allow to assess whether the array is authentic. The production of the boards described above will be possible thanks to the development of a prototype of the printing device, which the Applicant plans to use in industrial activities, after the project has been completed. This device will be able to print inks with the addition of chemical markers on the first generation reflective film and on prismatic films. The device will be characterised by a number of improvements, compared to the currently owned by the Applicant of the Industrial Multifunctional Graphic Device
Alla ricerca dei colori e dei tessuti del Mediterraneo

The local artisan products at risk of disappearing: we must consider whether to give new value to the tradition for new professions related to the sustainable use of local resources. The multifunctionality of agriculture can develop new job opportunities especially for rural women and the company has to deal with environmental protection, rural tourism, craft activities. The added value of traditional products is in their intrinsic qualities and sensory and cultural enhancement. The areas of study are the province of Grosseto in Tuscany, the province of Sassari in Sardinia and the Middle Campidano, the provinces of North and South of Corsica. The project aims to develop capacity for innovation, creation and application of processes and products in small and medium-sized enterprises of agriculture, handicrafts (textile-dyeing and herbal) and tourism. The project aims to enhance native species of plants and wool for the production of handicrafts and textiles for the use of green building and promote cultural tourism and territories with the educational-teaching. The targets are micro-enterprises and SMEs agriculture, crafts and tourism organizations that benefit directly and / or indirectly the development of rural areas. The activities will include: characterization of local resources and their intrinsic qualities and sensory integration of analysis with the application of marketing strategies and sensory environment of the territories as a basis for actions that promote the sustainability of each other territories of the three regions of the Tyrrhenian Sea.
PORO-HUESO (DISEÑO OPTIMIZADO DE CELOSÍAS ORTOPÉDICAS Y BIOMATERIALES EN LAS EXTREMIDADES)

ESTE PROYECTO CONJUNTO TIENE COMO OBJETIVO DISEÑAR E IMPLEMENTAR UNA SOLUCIÓN TECNOLÓGICA OPTIMIZADA PARA EL DISEÑO INNOVADOR Y LA PRODUCCIÓN DE BIOMATERIALES PARA PRÓTESIS ORTOPÉDICAS.  EN PARTICULAR, LAS TECNOLOGÍAS DE FABRICACIÓN 1.ADDITIVE (IMPRESIÓN 3D) SE UTILIZARÁN DE FORMA COMBINADA, CON HERRAMIENTAS DE OPTIMIZACIÓN DE PROCESOS RELACIONADAS;  2.I SW DE DISEÑO DE ESTRUCTURAS POROSAS Y OPTIMIZACIÓN TOPOLÓGICA DE LA MISMA, CON EL FIN DE CREAR UN ENFOQUE PARA EL DISEÑO
PROTRANSDUZIN-D - IMPROVED ENHANCER OF GENE TRANSFER

The invention relates to a polypeptide having the sequence Z1-Gln-Ala-Lys-Ile-Lys-Gln-Ile-Ile-Asn-Met-Trp-Gln-Z2. The polypeptide is used for retroviral transfection/transduction.
METEORISK - Mitigation of natural risks through improved forecasting of extreme meteorological events

Extreme meteorological events originate in one part of the Alps and proceed over or along the alpine crest. The effects of these events are inundations, landslides, avalanches, Föhn storms etc., which do not occur outside of the Alps in this form. The forecasting of these events is limited by the lack of structured communication between the weather services in these areas and the lack of online available data before and during these events. 
The object of METEORISK is: 
1- to establish a network of online automatic meteorological stations densifying the existing 
station network. 
2 - The improved interpretation of different regional models and radar data of the area. 
3 - Optimized communication, common training and networking between the forecasters. 
4 - The improvement of the interaction with the the civil protection authorities and the public 
through adequate instruction material. 
5 - A statistical analysis to quantify the occurence of extreme events in the different part of the Alps.
Effects of continuous positive airway pressure on cognitition and neuroimaging data in sleep apnea

Obstructive sleep apnea (OSA) has been associated with a broad range of neurocognitive difficulties. The current view is that the neurocognitive impairment in OSA is due to the adverse effects of sleep fragmentation and/or intermittent hypoxia. The overall picture of cognitive deficits in OSA is complex. On balance, there appears to be negative effects of OSA on cognition, most likely in the domains of attention/vigilance, verbal and visual delayed long-term memory, visuospatial/constructional abilities, and executive dysfunction. Continuous positive airway pressure (CPAP) is the most effective and widely used treatment of OSA. In the majority of studies of OSA patients treated with CPAP, attention/vigilance improved, but changes in global functioning, executive functioning, and memory improved in about half of the studies. This may be due, in part, to variability in study design and sampling methodology across studies. Structural volume changes have been demonstrated in brain regions of OSA patients including areas that regulate memory and executive function (e.g., frontal cortex, anterior cingulate, and hippocampus). Growing evidence suggests that the OSA-related changes in brain morphology may improve with CPAP treatment. Neuroimaging studies performed during cognitive testing have provided insight into CPAP's effect on function of neuroanatomical circuits in the brain. Although neuroimaging can provide important insights into the structural and functional differences associated with OSA, one of the challenges is to interpret the findings in light of comorbid conditions that also cause neural injury. The purpose of this article is to provide a narrative review of the publications on cognition and neuroimaging in OSA before and after CPAP treatment.
Training Convolutional Neural Networks Based on Ternary Optical Processor

A novel platform and algorithms of Ternary Optical Computer (TOC) are proposed to training Convolutional Neural Network (CNN). It can significantly improve the concurrency and throughput of the training process of CNN. Reviewing the irrelevance data and the inherent parallelism module of the CNN, this paper discusses the preprocessing way of arbitrary number of two-dimensional data which include feature maps, convolutional kernels and mini-batches. Then strategies of parallel training of CNN based on the reconfigurable flexible arithmetic operator are proposed. All these arithmetic units are implemented by the optical Modified Signed Digit (MSD) adder and optical MSD multiplier, which are carry-free differing from the electronic computers. The massive data-bits of TOC are reconfigurable and redistributable, so fully parallel pipeline of the CNN can be sufficiently achieved. The computational complexity of the algorithms in time are analyzed. The result shows that TOC has great benefits comparing to the GPU and FPGA in concurrency, needed cycle and hardware resources resumed. This paper provides a new perspective to efficiently address computation-intensive and data-intensive issues.
COOKING APPLIANCE

A cooking appliance (10) comprises a housing (11) which de- fines a food preparation cavity (12), heating means for heat- ing the cavity (12), and a door (14) for selectively closing and opening the cavity (12). The cooking appliance (10) is characterized by the cooking appliance (10) further comprising a horizontally movable linkage system connected to the housing and the door (14), wherein the linkage system is configured to move the door between a closed position in which the door bears against the front side (15) of the housing (11) to close the oven cavity (12), via an intermediate position in which the door is lifted off from the front side of the housing, and an open position in which the door is positioned laterally aside the oven cavity, wherein during the entire path of movement the door is held in a vertical orientation.
Enhancing Innovation and Sustainability in Adriatic Aquaculture

The project aims at building up synergies between industries and research Institutes to satisfy the innovation demand of Italian and Croatian farmed fish food chains. Thanks to advanced environment-friendly/cost-effective farming protocols, healthier and tasteful fish products will increase competitiveness of SMEs on regional and international markets. Following the suggestion of the EUSAIR action plan for the aquaculture sector, to strengthen stakeholder involvement and to improve skills and product diversification, the project will involve aquaculture-targeted research groups, fish farms, fish processing industries, public associations of both countries. Their pre-established collaboration will allow creating concrete actions addressed to fish farmers and SMEs processing the fish.
Rituales, derechos y relaciones: algunas donaciones y su interpretación en el cartulario de Fulda, c 827

This article analyses a cluster of legal documents concerning newly cleared woodland between the river Fulda and its minor tributary the Haune, copied into the earliest Fulda cartulary which was completed in 828. It elucidates the complex interactions between local landholders of varying status, the monks of Fulda and their claims to spiritual patronage and tenurial right, and the public world of legal ritual and county meetings which were central to the exercise of power in the Carolingian world. It argues that the legal rituals recorded in charters were simultaneously attempts to define and regulate the relationships between different social actors (individuals, groups and institutions) as well as to transfer rights over property. Historians need to pay particular care to the mechanisms of transmission, as the archival record wa s carefully constructed to meet immediate needs, and it may obscure the extent to which relationships and the rights embedded in them were matters of interpretation. As well as raising epistemological and methodological questions about the nature of the charter evidence, this discussion also sheds light on the nature of land claims and clearances, and the relationship between internal colonisation and the crystallisation of ecclesiastical and political structures under Carolingian rule, topics which parallel the concerns of much recent work on early medieval Iberia. Finally, it is argued that if charter sare read not of passive records of abstract rights but as active attempts to interpret social relations, they can shed some light on the identities and interests of landowners of relatively modest means, and place them at historiographial centre stage.