SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
“Epigenetic impacts on early-stage speciation and adaptive radiation”

Phenotypic plasticity plays a key role at the onset of the speciation process, facilitating diversification though the induction of novel phenotypes in response to distinct environments. Via genetic accommodation and genetic assimilation, this influence may extend throughout the speciation process and beyond, into subsequent speciation events. While the epigenetic regulation of gene expression that mediates phenotypic plasticity has been extensively studied in lab-based model organisms, very little is known about epigenetic variation in natural populations. This project will be the first epigenetic study explicitly focused on the speciation process. Using cutting-edge techniques, the applicant will characterize DNA methylation variation within and among the sympatric species of a recently discovered endemic cichlid fish radiation in Lake Massoko, Tanzania. Specifically the applicant will test: if 1) newly formed species differ in the distributions of epigenetic marks across the genome, 2) genomic variants linked to phenotypic divergence among species are in genomic regions unusually high in DNA methylation, as expected under a hypothesis of epigenetic differences preceding fixed nucleotide differences during adaptive divergence, 3) genomic regions diverging in patterns of methylation among incipient species are also exhibiting high levels of methylation in populations of Astatotilapia calliptera, the ancestral, colonizing species. The results of this pioneering project will provide the first empirical evidence of the importance of epigenetic variation during the emergence of new species.
Risk communication strategies

The concept of risk management includes a wide range of measures, which deal with natural hazards and which are divided into different topics such as prevention, protection, preparation, event management and reconstruction. A correct risk perception in the population and an efficient communication of risks, build up an important starting point to deal with natural hazards. The main objective of the project is the improvement of the collaboration between institutions and the population on the communication about the risk regarding natural hazards. It is in fact necessary to
increase the awareness in the population, through the development of specific communication tools. To this purpose the current status shall be surveyed at first and then good practice examples will be collected; these will be used to plan interviews and analysis of the needs concerning the different stakeholders and to develop tailor-made communication tools, such as a web platform. The activities to rise resilience will be completed by measures about the development of awareness for actors involved in risk management. Within the improvement of the risk awareness in border
zones such as South Tyrol and Carinzia, particular importance will be given to the presence of different languages, to gender mainstreaming and to socio-cultural aspects. The continuous exchange of information will build up a multiplier of the project results, which will be available to all the active subjects within the risk management.
Improvement of reliability of fire engineering equipment based on a jet-niche technology

The obtained results address the solution to problems on enhancing the reliability and operation efficiency of fuel consuming equipment at industrial and power engineering facilities in the course of low-cost modernization through the introduction of effective fuel combustion technology. Using statistical methods of experiment planning, regression dependences of boundaries of the detachment work of burners were obtained. Solving the optimization problems for the derived functions made it possible to select the values of fuel distribution parameters for natural and liquefied gases with the purpose of decreasing the operation technical minimum of FE loading. As a result, possibilities of starting the equipment at gas pressure Р start =10 Pа were achieved and minimally possible workload of FE was decreased up to 5…10 % of the nominal, which corresponds to the coefficient of working load regulation K R >10. The presented results on improvement of starting characteristics of burners, as well as reserving of natural gas by liquefying will make it possible to ensure reliability of FE operation. A decrease in starting consumption minimizes the possibility of gas contamination of the furnace space (explosiveness) and decreases thermal intensity of FE elements, preventing the thermal «shock» on the heat exchange surface of the equipment.
Study of the Hydrogen Activation Reaction on Nanosized MoS2 Particles under Hydroconversion Conditions

The mechanism of activation of a hydrogen molecule upon interaction with the surface of nanosized particles of the MoS2 hydroconversion catalyst has been modeled using a quantum-chemical method of the density functional theory (DFT) with the hybrid functional B3LYP/dgdzvp in the cluster approximation. Two clusters, Mo2S4 and Mo3S6, have been considered as structural models of nanosized catalyst particles. It has been shown that the primary event of interaction of molecular H2 with the catalyst surface is the chemisorption of hydrogen atoms on the molybdenum atom with H–H bond breaking. The local minima of the total electronic energy of the complexes in the chemisorption of hydrogen atoms on Mo and S atoms and the energy of the transition state between local minima have been found. It has been established that the stability of the complexes [Mo3S6…H2] varies in the order: [···MoH2] > [(S)H···(S)H] > [(Mo)H···(S)H] > [(Mo)H···(Mo)H] > [···SH2].
Full-term development of rats from oocytes fertilized in vitro using cryopreserved ejaculated sperm

For preservation of rat spermatozoa, the general-purpose method requires that the male be sacrificed for collection of spermatozoa from the epididymides. However, it would be highly useful if the ejaculated spermatozoa could be successfully cryopreserved and the frozen-thawed spermatozoa used for in vitro fertilization, since this would allow the genetically valuable rats to be maintained alive rather than sacrificed. The aim of the present study was to clarify whether ejaculated rat spermatozoa could be successfully cryopreserved and fertilized in vitro. The motility and viability of frozen-thawed ejaculated spermatozoa were similar to those of frozen-thawed epididymal spermatozoa (around 10%). The percentage of acrosomal integrity in epididymal spermatozoa was significantly higher than that in ejaculated spermatozoa after freezing/thawing. The level of capacitation-associated protein tyrosine phosphorylation in frozen-thawed ejaculated sperm was slightly increased at 5h. When the frozen-thawed ejaculated spermatozoa were used for in vitro fertilization, the percentages of fertilization, pronuclear formation, and development to the 2-cell stage (26.5%, 23.0%, and 91.0%, respectively) were similar to those of frozen-thawed epididymal spermatozoa (19.4%, 15.0%, and 84.1%, respectively). However, the rate of blastocyst formation in the ejaculated group was significantly lower than that in the epididymal group (12.0% vs 43.2%). Results from the embryo transfer experiment showed that the proportions of embryos developed to term were similar between the ejaculated (47.7%) and epididymal groups (53.7%). We showed here for the first time that ejaculated spermatozoa can be cryopreserved and the frozen-thawed sperm could be developed to term via in vitro fertilization in rats.
Shifting Tides in the Western and Central Pacific Ocean Tuna Fishery: The Political Economy of Regulation and Industry Responses

The Western and Central Pacific Ocean (WCPO) tuna fishery is the largest and most valuable in the world. Although the International Law of the Sea granted Pacific island countries the right to exploit and manage this valuable fishery, they have been unable to prevent resource decline or to capture economic development potential from their intersections with the global tuna industry. Variants of neoliberalism identify Pacific island countries' weak institutions to explain these failings. We argue that this explanation is insufficient. As an alternative, we offer a political economy analysis of the co-evolution of fisheries regulation and the strategies of the Japanese and Taiwanese fleets (and their governments) in the region. This framing illustrates the relational, multi-scalar processes within and among states and firms that shape patterns in the sector. Our findings indicate that the combination of competitive capital accumulation strategies and inter-state power relations must be addressed to explain challenges in the WCPO tuna sector.
Economics of Soybean Production: Evidence from Saboba and Chereponi Districts of Northern Region of Ghana

The objective of this study was to document soybean production practices, estimate the level of profitability and identify constraints to soybean production in Saboba and Chereponi districts of the Northern Region of Ghana based on gender. Primary data from 140 farmers were subjected to profitability analysis and Kendall’s Coefficient of Concordance. Soybean production was found to be unprofitable in Chereponi District for both male and female farmers but profitable for male farmers in Saboba District. Constraints to soybean production include lack of right over land, selling of produce on credit, among others. The level of profitability of soybean production can be improved by addressing constraints such as unfavourable land tenure arragements, unfavourable market conditions inter alia.
Endoplasmic reticulum stress in health and disease

Endoplasmic reticulum (ER) stress is emerging as a common feature in the pathology of numerous diseases including cancer, neurodegenerative disorders, metabolic syndromes and inflammatory diseases. Thus ER stress represents a potential therapeutic intervention point to be exploited to develop novel therapies, diagnostic tools and markers for these diseases. However, exploitation is hampered by the shortage of scientists with interdisciplinary training that can navigate with ease between the academic, industrial and clinical sectors, and that have the scientific and complementary skills, together with an innovative outlook, to convert research findings into commercial and clinical applications. This proposal will bring young researchers together with world-leading academics, clinicians and industry personnel, who are united in (1) their goal of forming a network of excellence aimed at understanding the ER stress response mechanistically and quantitatively and (2) applying this understanding to identify and validate the most suitable intervention points in order to provide innovative knowledge-driven strategies for the treatment of ER stress-associated diseases. 
The TRAIN-ERS network will provide early stage researchers (ESRs) with high quality scientific and complementary skills training combined with international, intersectoral work experience. This will produce highly trained, innovative, creative and entrepreneurial ESRs with greatly enhanced career prospects, who will continue to advance the state of the art in the Biomedical field in their further careers, and will confidently navigate at the interface of academic, clinical and private sector research. The TRAIN-ERS research programme will provide the ESR’s with the knowledge and the cutting edge scientific and technical skills that will drive our understanding and exploitation of the ER stress response for therapeutic and diagnostic purposes.
Diagnosis, Prospection and Internationalisation Plan A. Cantadeiro, Lda

This application aims to follow up the implementation of a strategy defined by A. Cantadeiro, Lda., which aims to start the process of internationalisation of the company, for markets strategically identified as target markets, France and Morocco.
Applying terrestrial lidar for evaluation and calibration of airborne lidar-derived shrub biomass estimates in Arctic tundra

ABSTRACTMonitoring of climate-driven expansion of low-stature shrubs in Arctic tundra can be improved through application of high-resolution remote sensing. However, the destructive nature of harvest sampling that is usually performed for validation of these data is resource intensive and can limit future comparisons by destroying benchmark measurements. We compared aboveground shrub biomass estimates derived from terrestrial laser scanning (TLS) and airborne laser scanning (ALS) with the goal of determining whether TLS data can be used to accurately calibrate ALS estimates of shrub biomass in Arctic tundra. We used a leave-one-out cross-validation calibration of canopy volume against harvested shrub biomass to establish predictive relationships between TLS canopy volume and harvested shrub biomass, and between ALS canopy volume and TLS-derived shrub biomass estimates. TLS produced more accurate predictions of shrub biomass (R2 = 0.78; root mean square deviation [RMSD] = 102 g) than did ALS, but the accur...
GESETZ 181 – IMBALPLAST S.R.L.

DER AUSBAU DER AKTUELLEN PRODUKTIONSSTÄTTE IN TEVEROLA (CASERTA) SIEHT DIE EINFÜHRUNG EINER NEUEN PRODUKTIONSLINIE FÜR DIE LIEFERUNG NEUER PRODUKTE IM SEGMENT „DIREKTMARKETING“ VOR, DIE DIE BEREITS IM BEREICH „MASSENDRUCK“ BESTEHENDEN PRODUKTE ERGÄNZEN WIRD.
Marine biodiversity as sustainable resource of disease-suppressive microbes and bioprotectants for aquaculture and crop diseases

MARBLES will use a novel and systematic approach to access and exploit marine microbial biodiversity for sustainable bioprospecting to discover microbial consortia and bioactive molecules for application in aqua- and agriculture and in the clinic. MARBLES' ecology-based bioprospecting strategy will focuses on unique host-microbe interactions in marine environments, including marine sponges, microalgae and fish, which rely on their microbiomes and microbial natural products for disease resistance. Partners’ existing microbial collections and new ones generated during MARBLES will be harnessed for the discovery of novel natural products and synthetic microbial communities. For this, MARBLES will use a systems-wide genomics approach to uncover the bioactive agents in disease-suppressive microbiomes. Also, MARBLES will explore host- and microbe-derived chemicals that elicit production of bioactive compounds, as elicitors to revitalise drug screening. The deliverables will be microbes and consortia and bioactive natural products, their derivatives and elicitors, which can be harnessed to fight infectious diseases in the agrochemical and aquaculture industries and in healthcare.  
Besides highly innovative, the approaches will be cost-effective and will offer advantages from both environmental and health perspectives in comparison to existing alternatives. The sustainable production of bioprotectants will increase the effectiveness of fish production - reducing the pressure on harvesting wild fish - and aid the transition of the crop agriculture sector towards bio-based and circular solutions. MARBLES will work closely together with a panel of SMEs and large companies from the EU aquaculture, crop protection biotechnology and health sectors. MARBLES fully complies with the Nagoya and Cartagena Protocols, and aims to make major contributions to the UN sustainable development goals, SDG 2, 3, 12, 13 and 14, as well as to current UN processes (BBNJ, DSI, SynBio)
Influence of position of auxiliary acceptor in D–A–π–A photosensitizes on photovoltaic performances of dye-sensitized solar cells

Several novel indoline dyes configured with donor–acceptor–bridge–acceptor (D–A–π–A) structures were designed and applied to organic dye-sensitized solar cells. These D–A–π–A dye molecules are composed of indoline (electron donating group), benzothiadiazole (BDT) (auxiliary acceptor), two furan rings (π-conjugated group), and 2-cyanoacrylic acid (electron accepting group). The influence of position of auxiliary acceptor in D–A–π–A organic sensitizer on the performance of photosensitize is investigated in detail. Calculated results show that the sensitizer could achieve a red-shifted absorption in long-wavelength region and a stronger absorption in short-wavelength region when the position of auxiliary acceptor changes from the donor to the acceptor. Moreover, among these dyes, WS-12, whose auxiliary acceptor nearing the 2-cyanoacrylic acid, possesses the better performance in terms of the charge transfer characteristics, lifetime of excited state as well as the vertical dipole moment when compared with WS-1 and WS-11. We hope that the present results could provide theoretical guidance for designing photosensitizes with higher efficiencies.
Coherent raman imaging for the molecular study of the origin of diseases

CRIMSON aims to provide a next-generation bio-photonics imaging device based on vibrational spectroscopy, with the potential to revolutionise the study of the cellular origin of diseases allowing for novel approaches towards personalised therapy. We will employ label-free broadband coherent Raman scattering (CRS) extended to the fingerprint region, in combination with artificial-intelligence spectroscopic data analysis, for fast cell/tissue classification with unprecedented biochemical sensitivity. We will develop a hyperspectral CRS microscope for 3D quantitative imaging of sub-cellular compartments in living cells and organoids. High acquisition speed will enable the observation of intra- and inter-cellular dynamic changes by time-lapse imaging. We will simulate future in-vivo studies and demonstrate the capability to image inside the body, realizing an innovative CRS endoscope and applying it to ex-vivo thick tissue slides. CRIMSON relies on the development of new compact ultrafast lasers, innovative broadband CRS detection schemes and advanced spectral analysis routines.
To validate the CRS platform, we will investigate three open biological questions related to cancer, as paradigmatic examples of the complexity and heterogeneity of cellular diseases. The results will have profound societal impacts, improving patients’ quality of life and reducing public healthcare costs.
CRIMSON brings together a multidisciplinary team of world-leading academic organizations, biomedical end users and innovative SMEs, with vertical integration of all required skills. CRIMSON will bridge the gap between research and product development, increasing the TRL and making CRS a user-friendly, robust and cost-effective mainstream tool for a vast biological research community. Commercial exploitation by the participating SMEs, including a biomedical equipment manufacturer, will create a competitive advantage in the European biophotonics-related market for microscopes and R&D tools.
Supplementary value of vetch (Vicia dasycarpa) hay as a replacement to concentrate mix in the diet of lactating crossbred cows

An experiment was conducted with the objective of replacing vetch for concentrate mix on feed intake and digestibility as well as milk production and composition in lactating F1 crossbred (Boran x Friesian) cows fed&nbsp; with a basal diet of urea-molasses-treated wheat straw. Eight crossbred cows of similar milk yield (8&ndash;10 kg d-1), body weight (BW) and stage of lactation (early lactation), but differing in parities were arranged in 4 x 4 double Latin square design. The treatments included offering urea-molasses treated wheat straw (UMTWS) ad libitum and supplementation with concentrate mix (T1), and replacement of the concentrate mix with vetch (Vicia dasycarpa) hay at a level of 25% (T2), 50% (T3) and 75% (T4). The concentrate mix consisted of 74% wheat bran, 25% noug seed (Guizotia abyssinica) cake and 1% common salt. In sacco degradability study showed that the concentrate mix and vetch were similar in rumen degradability parameters, except that rate of degradation was relatively faster for vetch hay. Total dry matter (DM) intake was significantly higher (P&lt;0.05) for cows in T3 compared to cows in the other treatments. Nutrient intakes and apparent digestibility were non-significant (P&gt;0.05) among treatments, except for cows in T3 that had higher (P&lt;0.05) acid detergent fibre (ADF) intakes than cows on T1 and T2. Crude protein (CP) and metabolisable energy (ME) intakes were sufficient to meet daily requirements for the observed mean daily milk yield of 6.5 kg. Cows in T1 produced higher (P&lt;0.05) milk yield compared to cows in T4. Milk compositions were similar (P&gt;0.05) for cows in the different treatments. It is concluded that vetch hay could substitute up to 50% of the concentrate mix without compromising feed intake and digestibility of nutrients as well as milk yield and compositions of lactating F1 Boran x Friesian cows.&nbsp;
PSR B0826-34: SOMETIMES A ROTATING RADIO TRANSIENT

We report on the detection of sporadic, strong single pulses co-existing with a periodic weak emission in the duration of weak mode of PSR B0826-34. The intensities and durations of these pulses are comparable with that of the sub-pulses in the strong mode, and these pulses are distributed within the phase ranges of the main-pulse and interpulse of the strong-mode average profile. These results suggest that there are most possibly sporadic, very short timescale turn-on of strong-mode emission during the weak-mode state of the pulsar. The emission features of the bursts of strong pulses of PSR B0826-34 during its weak-mode state are similar to those of the rotating radio transients (RRATs). PSR B0826-34 is the second pulsar known which oscillates between pulsar-like and RRAT-like modes.
Centro de Investigação Multidisciplinar da Universidade Cardeal Stefan Wyszyński em Varsóvia

O projeto diz respeito à criação do Centro de Investigação Multidisciplinar da Universidade Cardeal Stefan Wyszyński, em Varsóvia. Será um centro de pesquisa único na Polônia, que permite realizar pesquisas interdisciplinares nas áreas de ciências sociais, humanas, ciências médicas, TI e ciências naturais. O principal objetivo do projeto é aumentar a inovação da região da Mazóvia e do país, melhorar a competitividade da região e aumentar a transferência de inovação para a economia regional, aumentando a possibilidade de realizar pesquisas interdisciplinares e permitindo o uso da comunidade científica, empreendedores de infraestrutura de pesquisa moderna, usando as mais recentes tecnologias, especialmente TI e multimídia. O âmbito do projeto foi dividido nas seguintes fases executadas pelo requerente: 1. Os trabalhos preparatórios. 2. Preparação da documentação do projeto e do concurso. 3. Trabalhos de adaptação da infraestrutura de consórcios no domínio da sua adaptação às necessidades da instalação do aparelho. 4. Aquisição de equipamento para as necessidades dos consórcios. 5. Construção de instalações do Centro com infraestruturas de instalação, ligações e equipamento incorporado. 6. Receção dos edifícios do Centro por serviços administrativos e estatais — autorização de utilização das instalações. 7. Ordenamento do território relacionado com o investimento (verde, parques de parque, pequena arquitetura). 8. Aquisição e instalação das infraestruturas necessárias ao funcionamento do Centro e à formação. Os grupos-alvo para a execução do projeto consistem em: — Um consórcio científico criado para a execução do projeto; — outras universidades e unidades de investigação no domínio das atividades de investigação; — empresários interessados em utilizar infraestruturas de investigação e todas as entidades interessadas em utilizar a infraestrutura resultante para fins de I & D.