SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
SYSTEM AND METHOD FOR GAS MANAGEMENT

The invention relates to a system and method for managing gas within one or more receptacles in one or more locations. The system and method comprises a control system that is configured to analyse data relating to gas transfer operations to identify gas leaks and to calculate the rate of any gas leaks identified.
Ion-Gated interfaces for quantum phase devices

The aim of this ERC proposal is to develop a highly efficient tunable interface with ion-movement-mediated gating as a rich platform for novel electronic devices by using field effect controlling of quantum phase transitions. Working beyond conventional FETs, the new transistors will be build by combining novel layered semiconductor films grown by the CVD method: newly synthesized ionic material; and a well-defined interface optimized by surface analysis techniques; which jointly are able to boost the field effect control of carrier doping to the range required for switching quantum phases such as superconductivity in electrical transport, ferromagnetism in magnetization, and chiral or coherent light sources in optical applications.
The sub-topics are designed to cover sufficiently broad disciplines of material sciences, new device technologies based on electrochemical principles, and condensed-matter physics. Such a design will make the project high adaptable for success at different levels with clear defined objectives to: 1) develop new materials and material combinations for ion gated interfaces to establish a rich platform of quantum phases; 2) utilize these quantum phases for device functionalities enjoying the characteristic abrupt response in phase transitions and to establish control of magnetism by field effect; and 3) create light emitting devices for effectively correlating light emission with quantum phases.
The project represents an exciting new research field that is attracting the attention of many research groups around the world. The applicant is a well-established pioneer in developing this rapid growing and highly competitive field, where he achieved major milestones in design, fabrication and operation of quantum phase devices. Embedded in the strong material researches environment of the host institute and in his new group, it is the perfect timing for the applicant to fulfil the dream of creating a new paradigm of electronic devices.
Creating added-value chemicals from bio-industrial co2 emissions using integrated catalytic technologies

In 2017, EU GHG emissions, including emissions from international aviationEurope has successfully reduced its GHG emissions since 1990 levels. The pace of reducing CO2 emissions is positive, however it is projected to slow after 2020 resulting in difficulties to achieve EU’s reduction target of 55% by 2030 as planned in the European Green Deal. Additional measures and policies are foreseen in EU to forefront this situation. Negative emissions technologies, as carbon capture, utilization and storage (CCUS) ones are currently a priority to explore, especially in non-exploited industrial sectors such as the bio-based industry as they significantly contribute to CO2 emissions. CATCO2NVERS will contribute to reduce GHG emissions from the bio-based industries developing 5 innovative and integrated technologies based on 3 catalytic methods (electrochemical, enzymatic and thermochemical). It will transform waste-CO2 (up to 90%) and residual biomass from 2 bio-based industries into 5 added-value chemicals (glyoxylic acid, lactic acid, furan dicarboxylic methyl ester (FDME), cyclic carbonated fatty acid methyl esters (CCFAMEs) with production yields between 70-90%. Methanol which will not have an energetic use but will be used in CATCO2NVERS own technologies. These target chemicals will be used as building blocks and monomers to obtain biopolymers of 100% bio-origin. Industrial partners will validate the application of the obtained chemical building blocks on the most relevant markets. In addition, the waste-CO2 stream will be conditioned by removing potential inhibitors for the catalysts. CATCO2NVERS will meet some of the principles in green chemistry (atom economy, use of renewable feedstocks, reduce derivatives and use of catalysts instead of stoichiometric reagents). CATCO2NVERS will explore an energy and resource efficient scenario following an industrial symbiosis model to ensure a biorefinery process along the CO2 valorization chain with zero or negative GHG emissions.
Plano de combate ao COVID-19 - OZN Technology

Para cumprimento das recomendações da DGS nos locais de trabalho, a empresa pretende investir em equipamentos que evitem o contacto com superfícies, a requalificação do espaço e implementação de novos processos de trabalho que suportem o distanciamento social e a desinfeção regular das instalações.
Collaboration for innovation: establishment of a pan-nematode drug development platform

To target helminth elimination, a drug research and development (R&D) pipeline is needed to provide new chemotherapeutics that effectively eliminate or sterilize adult worms, thus bringing about the paradigm shift necessary to reach the 2030 SDG goals on health. Our consortium proposes to establish a R&D pipeline for anthelminthics targeting nematodes. The focus will be on soil-transmitted helminthiasis and onchocerciasis, since these infections are among the leading neglected tropical diseases. Ground breaking characteristics of the drugs developed within our project are that they will have a unique mechanism of action that, at best, will target multiple nematodes (pan-nematode) with an excellent safety profile, including no efficacy against non-targeted co-endemic species. We will benefit from collaborations with our industrial partners Bayer and Celgene providing preselected compounds to populate the early preclinical stages of the R&D pipeline. Compounds with the best profile will be progressed through preclinical studies. Corallopyronin A, a compound with proven efficacy against essential Wolbachia endosymbionts in filariae that has superiority to the gold standard doxycycline, excellent bioavailability and promising exploratory safety data will undergo state-of-the-art toxicity profiling to advance towards phase 1 trials. We will also evaluate oxfendazol and oxantel pamoate in clinical trials. They have already proven efficacious in animals or humans and will only require clinical trials according to current regulatory guidelines to be implemented. With this strategy, the consortium will ensure that a pipeline of drug candidates is available for treating onchocerciasis, especially should current candidates fail in upcoming clinical trials. Moreover, we will establish a much-needed drug R&D pipeline to treat soil-transmitted helminth infections for which there is currently neither a drug with good efficacy against all species nor any prospects on the horizon.
Fs marine+: hydrogen syngas injection unit for ships to save fuel and cut emissions

FS MARINE+ is the world's first hydrogen-powered engine assistant unit for ships. The patented hydrogen generator produces a proprietary synthetic gas that is injected into a ship's engines to significantly improve combustion efficiency.
FS MARINE+ has been proven to reduce net fuel consumption by at least 10%, cut carbon dioxide (CO2) emissions by at least 10%, cut nitrogen oxide (NOX) emissions by at least 50%, and save at least 33% on engine maintenance costs.
The customizable unit can be installed on any vessel, and the cost amortized within three years. This makes FS MARINE+ the most viable technology for overcoming the shipping sector’s environmental and economic challenges. Regulations require ships to reduce CO2 by 10% every five years. Struggling operators must cut fuel costs, which make up 50-60% of expenses.
For an average ship, FS MARINE+ will save €2.9M in fuel and maintenance costs and prevent 19,200 tonnes of CO2 over 10 years. The company offers ROI-based pricing and build-lease-transfer options to make it accessible even for cash-restricted shipping companies.
As a pioneering technology innovation, FS MARINE+ has no direct competition and is protected by two patents. Indirect competition comes from energy efficiency and pollution abatement methods that have inferior outcomes.
There are 50,442 seagoing vessels worldwide, and 16,500 inland vessels registered in Europe. 50% are viable for FS MARINE+. This creates a total reachable market size of €28.1 billion. The company aims to sell 379 units and earn €181M in revenue by 2021. Demand and willingness to pay have been demonstrated through pre-commercial test and sales agreements from 11 shipping companies with a combined fleet of 159 vessels.
FS MARINE+ is the innovation of FUELSAVE GmbH, a German engineering company founded in 2012. It is now applying for Horizon 2020 Phase 2 to commercialize and roll out its beneficial innovation across European markets.
Smoking and health: association between telomere length and factors impacting on human disease, quality of life and life span in a large population-based cohort under the effect of smoking duration

Reactive oxygen species (ROS) are of primary importance as they cause damage to lipids, proteins, and DNA either endogenously by cellular mechanism, or through exogenous exposure to environmental injury factors, including oxidation insult factors, such as tobacco smoke. Currently 46.3 million adults (25.7 percent of the population) are smokers. This includes 24 million men (28.1 percent of the total) and more than 22 million women (23.5 percent). The prevalence is highest among persons 25-44 years of age. Cigarette smokers have a higher risk of developing several chronic disorders. These include fatty buildups in arteries, several types of cancer and chronic obstructive pulmonary disease (lung problems). As peripheral leukocytes have been the main target of human telomere research, most of what is known about human telomere dynamics in vivo is based on these cells. Leukocyte telomere length (TL) is a complex trait that is shaped by genetic, epigenetic, and environmental determinants. In this article, we consider that smoking modifies leukocyte TL in humans and contributes to its variability among individuals, although the smoking effect on TL and its relation with other metabolic indices may accelerate biological aging and development of smoking-induced chronic diseases in a large human population-based cohorts with smoking behavior. Recent studies confirmed that individuals with shorter telomeres present a higher prevalence of arterial lesions and higher risk of cardiovascular disease mortality. This study originally suggests that efficient therapeutic protection of TL and structure in response to stresses that are known to reduce TL, such as oxidative damage or inflammation associated with tobacco smoking, would lead to better telomere maintenance. Recently, we have discovered the potential use of telomere-restorative imidazole-containing dipeptide (non-hydrolized carnosine, carcinine) based therapy for better survival of smokers. We conclude that a better therapeutic or nutritional maintenance of TL may confer healthy aging in smokers and exceptional longevity in regularly ROS-exposed human survivors.
Krts - the art of losing weight

KRTS The Art of Losing Weight TM is an interactive on-line psychological boot camp that is supported by audio and video. Using a unique, innovative approach, it takes people who are struggling with their eating and weight from feeling frustrated and helpless, to having a focused and empowered mind-set. It also enables them to follow an individual blueprint detailing the necessary action to achieve their weight loss goal. It can be accessed virtually from anywhere in the world using the Internet. A long term outcome of the programme will be to reduce the societal challenge of pressure on the NHS and other European Health Systems caused by obesity related problems. The problem to be solved is the rise in levels of obesity which has been seen in the UK and internationally.
Topographic shading influences cryoconite morphodynamics and carbon exchange

Cryoconite holes are the most active and diverse microbial habitats on glacier and ice-sheet surfaces. In this article the authors demonstrate that the shape of cryoconite holes varies depending on ice-surface topography and that this has implications for the carbon cycling regime within. Net ecosystem production is shown to be controlled primarily by sediment thickness within holes. The authors show that irregular hole shapes are indicative of hole migration away from topographic shade, which promotes carbon fixation at the mesoscale on ice surfaces. A cellular automaton is used in conjunction with sediment-delivery experiments to show that migration is the result of simple sediment transfer processes, implying a relationship between ice-surface evolution and cryoconite biogeochemistry that has not previously been examined.
Fine tune of cellular behavior: multifunctional materials for medical implants

Bio-TUNE aims to develop innovative multifunctional materials to produce a new generation of medical implants with cell instructive and antibacterial potential.

In biomaterials science, it is well accepted that implant biointegration with surrounding tissues is a major goal. However, implant surfaces that facilitate cell adhesion, may also favor colonization of bacterial cells. Infection of biomaterials and subsequent biofilm formation can be catastrophic and significantly reduce patient quality of life, representing an emerging concern in healthcare.

On the other hand, research efforts devoted to inhibit bacterial colonization are frequently related to cytotoxic agents or treatments that do not positively affect host tissues. Hence, ideally, to enhance the long-term success of medical implants, biomaterial surfaces should reduce bacterial colonization levels without compromising the physiological functions of eukaryotic cells. Yet, the majority of current approaches tend to only focus on either improving cell adhesion or preventing bacterial infection but rarely explore a combined effect.

In Bio-TUNE we focus on multifunctional coatings to simultaneously address and mitigate both these problems. Thus, Bio-TUNE introduces a new mindset and different paradigms in the development of biomaterials to respond to unmet clinical needs.

Bio-TUNE ambitions to 1) Study and understand the interaction of eukaryotic cells with bacteria at the biophysical and biomolecular level; 2) To develop cell instructive and antibacterial surfaces via biochemical and topographical approaches; 3) Transfer this technology to medical implants.

We seek to decipher the mechanistic of eukaryotic and bacterial cell competition, generate new selective and multi-potential coatings and topographically-active patterns, and their technological transfer leading to a generation of advanced biomimetic materials for tissue regeneration and personalized medicine.
Dwarf galaxy planes: the discovery of symmetric structures in the Local Group

Both major galaxies in the Local Group (LG) are surrounded by thin planes of mostly co-orbiting satellite galaxies, the vast polar structure (VPOS) around the Milky Way (MW) and the Great Plane of Andromeda (GPoA) around M31. We summarize the current knowledge concerning these structures and compare their relative orientations and properties in a common coordinate system. The existence of coherent satellite structures motivates an investigation of the distribution of the more distant non-satellite galaxies in the LG. This results in the discovery of two planes (diameters of 1-2 Mpc) which contain almost all nearby non-satellite galaxies. The two LG planes are surprisingly symmetric, inclined by only 20 deg relative to the galactic disc of M31, similarly thin (heights of ~60 kpc) and have near-to-identical offsets from the MW and M31. They are inclined relative to each other by 35 deg. Comparing the plane orientations with each other and with additional features indicates an intimate connection between the VPOS and the GPoA. They are both polar to the MW, have similar orbital directions and are inclined by ~45 deg relative to each other. The Magellanic Stream approximately aligns with the VPOS and the GPoA, but also shares its projected position and line-of-sight velocity trend with the dominating structure of non-satellite dwarf galaxies. The proper motion of M31 indicates a prograde orbit of the MW-M31 system, the VPOS and the GPoA. The alignment with other features such as the Supergalactic Plane and the over-density in hypervelocity stars are discussed as well. We end with a summary of proposed scenarios trying to explain the LG galaxy structures as either originating from cosmological structures or from tidal debris of a past galaxy encounter. There currently exists no full detailed model which satisfactorily explains the existence of the thin symmetric LG planes. (abridged)
Dignità, Nobiltà ed Eccellenza: le donne illustri nell’opera di Cristoforo Bronzini

A partire dal 1404, con la pubblicazione della Città delle dame di Christine de Pizan, in Europa si assiste alla nascita del complesso dibattito intorno alla natura e alle virtù femminile. Molti sono gli autori e le autrici che partecipano attivamente alla Querelle des femmes, interrogandosi sul ruolo sociale, artistico e politico della donna. I difensori e i detrattori della causa femminile si confrontano attraverso discorsi polarizzanti che caratterizzano ed occupano oltre due secoli di letteratura europea. Le opere della querelle mettono in discussione l’immagine della donna come soggetto naturalmente inferiore, ripercorrendone la storia dell’accesso all’istruzione e dei rapporti matrimoniali. La tradizione classica degli exempla viene utilizzata da diversi autori che si servono di modelli femminili appartenenti alla storia e alla mitologia per affermare e difendere l’uguaglianza tra i sessi. Nel presente articolo si seguono gli esempi proposti da Cristoforo Bronzini nel suo Della Dignità e della nobiltà delle donne (1622) e si tracciano i profili delle donne, reali ed immaginarie, che hanno contribuito allo sviluppo del processo di emancipazione femminile tuttora in corso.
Twinning for european excellence in island biodiversity genomics

Biodiversity genomics is transforming our understanding of biological diversity and leading to new discoveries that can limit biodiversity decline and therefore benefit human societies. Island biotas are highly vulnerable and thus require efficient conservation and sustainable development. They are also prime model systems for applied and fundamental research in organismal biology. iBioGen aims to significantly enhance the scientific and innovation performance of a Widening country (Cyprus) in biodiversity genomics, with focus on island biodiversity. As the third-largest island of the Mediterranean, Cyprus is an ideal site for island biodiversity research, but local capacity is currently lacking. iBioGen is recognising the great potential of novel DNA methodology for future island biodiversity research and the need for methodological unification and theoretical synthesis in this new field. Twinning of the University of Cyprus (UCY) with three internationally-leading partners in biodiversity genomics (NHM), island biodiversity research (CSIC) and biodiversity modelling (CNRS) will: (i) stimulate research excellence and international visibility of UCY, (ii) improve networking efficiency and interdisciplinarity, and (iii) have broad societal and environmental impact towards valuing and protecting island biodiversity. These objectives will be achieved through a set of training, networking and dissemination activities, including: staff exchanges, on-site training and an international summer school, international symposia on methodological unification and theoretical synthesis, outreach events directed towards biodiversity stakeholders and local communities. The expected impacts include an increase in scientific output and successful research proposal applications of UCY, establishment of an EU island network of Genomic Observatories, and integration of new technologies in biomonitoring and environmental policy at regional and EU level.
Advertising as a possible determinant of private consumption

Private consumption represents an important component of aggregate demand, i.e. private consumption becomes a significant aspect of GDP determination. The objective of this paper is to examine private consumption in terms of a potential short-run influence of advertising on private consumption as one of the factors that determine consumption. GDP (disposable personal income), interest rates, but also advertising may be considered as important factors that can accelerate the development or change the direction of development of private consumption. A debate on effects of these factors is carried on in the paper. Determinants of advertising expenses as well as potential influence of advertising on private consumption will be studied. This general theme will be specified under conditions of American economy and examined during a period of almost 80 years (1929-2008). The GLS method of estimation with application of Cochrane-Orcutt regression is used. Despite of lower statistical significance the model indicates that advertising expenses variable is not an important variable of private consumption at aggregate level on the contrary to disposable personal income and private savings.
Research productivity in neurosurgery: trends in globalization, scientific focus, and funding

Object While research is important for the survival, growth, and expansion of neurosurgery, little work has been done to quantify the status and trends of neurosurgical publications. The purpose of this bibliometric study was to quantitatively analyze trends in neurosurgical publications, including changes in worldwide productivity, study methodology, subspecialty topic, and funding. Methods This was a retrospective bibliometric study using MEDLINE to record all publications between 1996 and 2009 by first authors affiliated with neurosurgical departments. Country of origin, MEDLINE-defined methodology, study topic, and funding sources (for US articles) were recorded. Linear regression was used to derive growth rates. Results Total articles numbered 53,425 during the study period, with leading global contributors including the US with 16,943 articles (31.7%) and Japan with 10,802 articles (20.2%). Countries demonstrating rapid growth in productivity included China (121.9 ± 9.98%/year, p &lt; 0.001), South Korea (50.5 ± 4.7%/year, p &lt; 0.001), India (19.4 ± 1.8%/year, p &lt; 0.001), and Turkey (25.3 ± 2.8%/year, p &lt; 0.001). While general research articles, case reports, and review articles have shown steady growth since 1996, clinical trials and randomized controlled trials have declined to 2004 levels. The greatest overall subspecialty growth was seen in spine surgery. Regarding funding, relative contribution of National Institutes of Health (NIH)–funded publications decreased from 30.2% (290 of 959) to 22.5% (356 of 1229) between 1996 and 2009. Conclusions Neurosurgical publications demonstrate continued increases in productivity as well as in global expansion, although US contributions remain dominant. Two challenges that the neurosurgical community is facing include the preponderance of case reports and review articles and the relative decline in NIH funding for US neurosurgical publications, as productivity has outpaced government financial support.