SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Arthroscopic regenerative medicine for early-stage treatment of oa

Osteoarthritis (OA) affects about 10% of the global population. It has a major impact on a patient’s quality of life; with pain and physical function being worse than chronic obstructive pulmonary disease or even cardiovascular disease. Its prevalence is increasing, by 2020 it will be the 4th leading cause of disability. OA is caused by ‘wear and tear’ and currently only symptoms are treated using pain killers until major surgery is needed, then the joint is replaced. Although joint replacements have improved and often last over 30 years, they do fail with about 10% of all joint replacement operations being to fix a failed implant. 
In this project JRI is working with University Medical Center Utrecht (UMCU), The Netherlands and the Cell and Gene Therapy Catapult (CGT), UK, to develop a new treatment of OA in the hip and take it to market. This involves catching the disease early when it appears as a distinct lesion. JRI has developed Hummingbird, a system that can get into the complex anatomy of the hip and precisely cut out patches of diseased tissue. Then treating these patches with a cell-based treatment developed by UMCU and successfully used to treat OA in the knee.
JRI believes that this treatment can be provided at a competitive price and at a scale to meet the global market. However, to do this they will need to build a robust business case and define in detail the regulatory pathways to the markets in Europe and USA. They will do this by working with CGT.
This Feasibility Study is the first phase of this work. With CGT, JRI will define: the regulatory pathway, the cost of providing the treatment, the reimbursement methods and the likely market share. The second phase will be in the first-in-human study and a critical step in both meeting the regulations and defining the benefits to this cell-based treatment being applied to the hip.
This treatment may not cure OA, but should delay major joint surgery and, in time, may allow some to avoid it all together.
COMPOSITIONS CONTAINING SULFER HEXAFLUORIDE AND USES THEREOF

Provided are novel azeotrope-like compositions of SF6 and N2O, as well as methods of using the same. Also provided are methods of using SF6 compositions, including azeotrope-like compositions, including a method for suppressing an electric arc or corona discharge and a method for flame suppression. Further provided are electrical devices using such SF6 compositions as a dielectric insulating gas and rigid closed-cell foams having such SF6 compositions within the cells, wherein the foam is both thermally and electrically insulative.
Enhancing market readiness for nzeb implementation

Although legal obligations are provided at National level by transposing the provisions of the 2010/31/EU Directive, the Nearly Zero Energy Building (nZEB) concept does not seem to be easily applicable yet in many countries. Previous research showed that defining the cost-feasible optimal integration of the technologies suitable for nZEB and the skills gaps experienced by the building sector are among the most important barriers. Current qualification courses and training schemes are still not satisfactory and underdeveloped to face the challenge of effective nZEB implementation, while the recourse to skilled professionals for renovations and new constructions of buildings is not usual practice. Despite strong political push towards nZEB and deep energy renovation, the traditionally conservative real estate market is still slow in the uptake of the new building standards and practices, especially in the residential sector. 
To respond to the challenge and use the emerging opportunities, the nZEB Ready project aims to act at market level in order to stimulate the demand for energy-related skills of construction workers and specialists in the involved countries and beyond and to increase the market readiness for an effective nZEB implementation: (1) by addressing the key identified barriers of nZEB implementation in focused markets, (2) by supporting the enhancement of skills framework by new market driven mutual recognition training and certification scheme for nZEB deployment that will facilitate the necessary legislative changes and (3) through development and communication of toolboxes, tailored guidance and practical support to engage home owners and public authorities to reach the nZEB benefits.
The project will address the challenges in Bulgaria, Croatia, Portugal, Poland and Romania in order to exploit synergies related to common climatic zones, traditions and opportunities to use the benefit of a larger and easily accessible regional market.
Impact of Megacity Jobs-Housing Spatial Mismatch on Commuting Behaviors: A Case Study on Central Districts of Shanghai, China

This studyutilized the mobile signaling data to conductthe impact analysis of jobs-housing spatial mismatch on commuting behavior, with eight typical employment centers of three categories selected as the research subjects. Based on the analysis of the characteristics and indictors including commuting distance, accessibilities from cumulative opportunity model etc., this study demonstrates that (a) cumulative percentage of short commuting distance (e.g., less than 3 km) reflects the jobs-housing spatial match between employment centers and their peripheral areas; and (b) combining the indicators of employed population and area covered within a certain space-time range among indictors of accessibility, it is possible to identify the degree of jobs-housing balance and efficiency of the transport system. According to the evaluation radar maps, the authors believe that employment centers could be divided into three categories: those with a gathering power, those with improvable functions, and those with local adjustment potentials. Possible measures including controlling the gathering power of the city centers, improving the function mix and transport facilities, and optimizing the overall local environment, etc. could be made to achieve jobs-housing balance in central districts and their peripheral areas as a whole. Besides, the study, proceeding from the perspective of commuters, suggests that optimization of jobs-housing distribution along banded corridors would be more efficient than those within the traditional region so as to reduce commuting traffic load.
Building the case for automated building energy management

Energy consumption in buildings comprises a significant fraction of total worldwide energy consumption and is strongly influenced by occupant behavior. To explore the quantitative effect of particular occupant actions on building energy consumption, we have evaluated eight energy-saving behaviors, as well as the of an in-home display (IHD), in 10 homes over the course of ten weeks. The results showed maximum savings ranging from 0%-20% attributed to the IHD, indicating that real-time feedback combined with actionable suggestions can motivate substantial conservation. By examining the data along with pre and post-experiment surveys, we conclude that automation is necessary to ease the more tedious tasks such as unplug when not in use and unplug the TV, where fewer than half of the highly capable and motivated participants performed the actions.
A Sketch of the Religious History of the Negroes in the South

“A Bout the last of August came in a Dutch man of warre that sold us twenty negars.” Thus reads the ancient official record which chronicles in those few words one of the most fateful events that has found place in the annals of our country, the introduction of African slavery. The year was 1619, and the place was the little colony of Jamestown, then in the thirteenth year of its existence. The institution at once took root downward and bore fruit upward. The trade rapidly grew and the market enlarged despite many earnest protests, until throughout the thirteen colonies ready sale was found for all the slaves that were offered. The traffic continued for one hundred and eighty-nine years, and when it was finally suppressed in 1808, there was a slave population in the United States numbering considerably over one million. From the first the most popular market was in the South, and ultimately the institution became localized in that section. This was not because of difference of mental and moral attitude in the two sections, but because of different climatic and economic conditions.
Ferroelectric nanocomposites for enhanced solar energy efficiency

Solar photovoltaics (PVs) and sustainable fuel production from photocatalysis are key technologies to displacing fossil fuel use. However, in order to drive rapid growth in PVs, and the commercial viability of photocatalytic solar fuel production, innovative technological approaches are needed to increase efficiencies while keeping costs low.

FENCES aims to demonstrate a new mechanism for solar energy conversion and use this to drive up the efficiencies of these key technologies. This will draw on a phenomenon found in ferroelectrics, known as the bulk photovoltaic (BPV) effect. While this has demonstrated photovoltages above the theoretical limit for conventional PVs, efficiency has remained low due to poor light absorption and charge transport. FENCES will overcome these limitations by intimately combining ferroelectrics and photoactive materials in nanocomposite thin films. This will couple the high electric field from the ferroelectric to the photoactive material, demonstrating novel behaviour with the potential to exceed the performance of current technologies.

In order to achieve this, FENCES will:
1. Design and synthesise optimal ferroelectric nanostructures and gain control over their properties, including the BPV effect, through careful study and tuning of the material properties in both precision model systems and low-cost, solution-based materials;

2. Develop detailed device models to accurately describe and predict the behaviour of these novel devices, incorporating progressive knowledge and understanding throughout the project using both empirical data and computational modelling;

3. Use these models to predict the optimum materials, structures and designs to demonstrate this novel technology and optimise device performance;

4. Fabricate and test proof-of-concept devices based on these optimised designs to validate the models and prove the hypothesis, establishing a new frontier in solar energy generation and wider science.
Investigating human neuronal transplantation integration and interaction at the single cell level

NeurTransHet will shed light on the heterogeneity of neuronal transplantations and the relationship with their environment. The aim of this project is to bring neuronal transplantation closer to clinical implementation by understanding the intricacies of individual transplanted cell contribution, and later applying this knowledge to engineer them. Neuronal loss underlies various brain disorders, such as Alzheimer’s disease, and injuries, such as traumatic brain injuries, resulting in life-long impairment. For example, dementia, a widespread (a new case every 3 seconds worldwide) condition stemming from neuronal loss, has devastating effects on the patients, their families and their communities. Thus, approaches aiming at replacing the lost neurons by transplantation are not only attractive from a health perspective, but also from a socio-economic standpoint. Many studies have explored neuronal transplantation, albeit with varying degrees of success. This is due to a lack in our understanding of how transplants integrate and interact with their host environment. Additionally, several studies gave evidence that transplanted cells are a heterogenous population, however, so far this heterogeneity has not been addressed in terms of function on integration and interaction. The recent advent of single cell transcriptomic technology, coupled with imaging techniques providing high-resolution spatial information, makes it possible to go beyond global interaction and closely dissect the individual neuronal transplants and their environment. Moreover, the possibility of transplanting cells of human origin in mice increases the clinical relevance of the results. During this two-year fellowship under the supervision of Prof. Dr. Magdalena Götz, who is a world-renowned scientist in neuronal cell replacement methodologies, I will transition into an independent research group leader investigating the role of cell heterogeneity in disease.
Amphiphilic nature of polyethylene glycols and their role in medical research

Abstract Background Polyethylene glycol (PEG) is a polyether compound which is an excellent candidate to study possible specific interactions of protein-polymer systems at the atomic level. Such studies would be beneficial in obtaining a more thorough understanding of PEG-protein interactions and might help to explain PEG's effects on protein behavior when used as a crowder. Scope of review PEGs has been called double edged sword showing assorted effects on the protein due its hydrophilic, hydrophobic and amphiphatic nature. It has been observed that the stabilization of the protein due to PEGs is because of exclusion volume effect (hard core interactions) shown by the higher molecular sizes of the crowder, however there are soft (chemical) interactions also which leads to destabilization of proteins. Most of low molecular size PEGs are noticed to destabilize proteins due to soft interactions. General significance Here, the core characteristics of the polyethylene glycols that are responsible for the various interactions with proteins and trying to delineate the behaviour of PEGs being ambiguous, are discussed. To conclude its paradox nature being a factual inert molecule or not, many different reports of PEG interactions with various proteins are clubbed together. In addition, owing to low toxicity, high polarity, high water solubility, typically unhydrolysing or undeteriorating characteristics, it has a practical significance in pharmaceutical and cosmetic industries, and in the research field on which this review shall enlighten from earlier to now.
Israel, Jordan, and their Efforts to Frustrate the United Nations Resolutions to Internationalise Jerusalem

From 1948 to 1950, the United Nations (UN) endeavoured to promote the internationalisation of Jerusalem, which had been a key element of the 1947 Palestine “Partition Plan.” Even though the war that erupted in Palestine in 1948 put paid to partition, 2 UN resolutions re-affirmed the decision to place the city under international auspices. On the opposite side stood Israel and Jordan, both of which ruled the city and were interested in frustrating the attempt to remove it from their control. This identity of interests stirred them to try to reach agreement to divide Jerusalem and make internationalisation superfluous. Unlike other studies that examine the contacts between Israel and Jordan during this period, this analysis examines the Jerusalem question as an independent issue and focuses on the moves made by Israel and Jordan during their covert negotiations in light of the UN decision to internationalise the city.
IOT Based Smart Irrigation System

In the present era one of the greatest problems faced by the world is water scarcity and agriculture being a demanding occupation consumes plenty of water. Therefore a system is required that uses water judiciously. Smart irrigation systems estimate and measure diminution of existing plant moisture in order to operate an irrigation system, restoring water as needed while minimizing excess water use. With the water requirements in irrigation being large, there is a need for a smart irrigation system that can save about 80% of the water. This prototype aims at saving time and avoiding problems like constant vigilance. As technology is advancing, there is always a chance of reducing risks and making work simpler. Embedded and micro controller systems provide solutions for many problems. This application precisely controls water system for gardens by using a sensor micro controller system. It is achieved by installing sensors in the field to monitor the soil temperature and soil moisture which transmits the data to the microcontroller for estimation of water demands of plants.
End to End Logistics Cost of Companies Operating in Sipcot, Tamilnadu

Logistics is considered as third profit source, plays an extremely important role in the process of the modern industrial production. At present it has become more and more difficult for the enterprises to only bank on on their ability to create techniques to obtain the viable competitive advantage. Therefore, the enterprise is prompted to turn their attention to the logistics sector, which is called as “the third profit source” of the organisation. This makes sense because the logistics function employs capital, incurs cost, and adds value by distribution. It even contributes to sales through the customer service provided. All the prerequisite elements exist for establishing a profit center. This study analyze the End to End logistics cost of companies located within SIPCOT, Tamilnadu. It also establishes relationship between logistics cost and various factors.
Twinning in atmospheric plasma science and applications

The main aim of the project is to enhance the research capacity conducted at the Electromagnetics and Novel Applications Lab (ENAL) of the University of Cyprus (UCY) through targeted twinning activities with internationally leading research institutions, namely the Leibniz-Institut für Analytische Wissenschaften- ISAS-e.V. (ISAS), and University of Jaén (UJA) in Spain. In particular, the aim will be to stimulate excellence and innovation capacity at UCY primarily in the field atmospheric pressure plasma (APP).  The focus will be on fundamental science on instrumentation and applications of the APP. The Twinning activities will include knowledge transfer, exchange of best practices between UCY, UJA, and ISAS, networking with research institutions and industry. The knowledge transfer will be achieved through in person training, webinars and PhD summer schools. The results and networking will be disseminated via participation at international and national conferences and also targeted events for the stakeholders. This project will entail significant benefits for all institutions involved in terms of enhancement of their Research and Innovation (R&I) capacity in science and technology and raising their staff’s research profile. It is expected that by the end of the project the consortium will have a core group of researchers (young and experienced) with considerable expertise in numerical simulations and modelling of APP, fabrication and characterization of APP and advanced mass spectroscopy with APP. The critical mass of researchers will be able to make a significant contribution to improving the research and innovation index of Cyprus. It is also expected that the Twinning project will lead to long-term collaboration between the three partners on joint proposals and projects, joint PhD students, infrastructure sharing and innovation through some of the novel applications that will be explored during the project.
OS017. Maternal death risk factor score based on hospital reference pattern and maternal condition of eclamptic woman in Soetomo Hospital, Surabaya, Indonesia

Maternal Mortality Rate in Indonesia is still high, around 230/100,000 live birth in 2005. Eclampsia is the second most cause of maternal death (about 13%). We have a very high prevalence of eclampsia in our center (Surabaya) about 1.08% of all delivery. One of our main problem about eclampsia case is multiple referral hospital system, because we do not have many tertiary center for this case. We assumed that high incidence of maternal death because of eclampsia is caused by this factor.To evaluate relationship between hospital referral system and maternal condition of eclamptic woman with maternal death event and develope scoring system to predict maternal death event on eclamptic woman.This is a case control study with retrospective observational analytic design, involve all eclamptic woman whom reffered and admitted to Soetomo hospital (Indonesia) from 1 January 2005 until 31 December 2009. Total eclamptic woman was 160 cases, with 12 maternal death on case group and 148 survive maternal on control group. Research variable includes maternal condition (ages, parity, eclampsia type, complication) and hospital referral pattern (ANC, Magnesium Sulfate, anti-hypertensive drugs, multiple hospital referral, health workers accompanion during patient referral). Primary outcome includes maternal death.There is significant association between multiple hospital referral (RO 6.1, P=0.083), maternal age >35 (RO 17.4, P=0.032), lung oedema (RO 19.1, P=0.065), renal failure (RO 98.8, P=0.002), intra cranial hemorrhage (RO 6319.7, P⩽0.0001), Eclampsia type (RO 0.009), on eclamptic women with maternal death. No significant association between parity (RO 0.3 P=0.310), HELLP syndrome (RO 2.2 P=0.478), Magnesium Sulfate given before patient reffered (RO 0.7, P=0.685), ANC quantity (RO 0.9 P=0.844), health workers accompanion during referral (RO 0.9, P=0.901), on eclamptic women with maternal death event.There are 6 significant variable includes Maternal complication (ICH, renal failure, lung oedema), Maternal ages >35 years, antihypertensive drugs, multiple hospital referral, multiparity, and eclampsia type that can be made a scoring system. We develop scoring system based on risk factor that can be used to predict maternal death event on eclamptic woman.
Nonlinear rock and roll - modelling and control of parametric resonance in wave energy converters

The title of this project is ‘Nonlinear Rock and Roll – Modelling and Control of Parametric Resonance in Wave Energy Converters’.  The over-arching aim is to catalyse increased research into parametric resonance (PR) within wave energy and other offshore renewable energy fields. 

The concept of resonance is well known in the study of wave energy converters (WECs). In comparison, PR has received virtually no attention, and is often unexpected since it is a nonlinear phenomenon not predicted by the linear/frequency domain models traditionally favoured in WEC research and analysis. Whereas normal resonance causes the oscillations of a system to grow linearly with time, PR causes an exponential increase in oscillation amplitude, and therefore has great potential to be either detrimental or beneficial to a WEC performance. For certain classes of WECs, PR can lead WEC instability and decreased performance, by transferring energy from the primary mode of motion into other modes. Alternatively, for other types of WECs designed to extract power from the parametrically resonating modes of motion, triggering PR could result in increased energy capture and represent a game-changing approach to improving WEC performance.

To achieve the over-arching goal, the project focuses on the following  specific objectives:
1) Demonstrate novel control techniques to either mitigate or harness PR for different classes of WECs.  
2) Provide opensource tools for modelling and analysing PR in WECs, to aide the wave energy community in overcoming the barriers surrounding the advanced nonlinear methods required to investigate PR.  
3) Strong communication, dissemination and exploitation activities. Providing information to the wave energy community and connections with  researchers from other disciplines with relevant knowledge and experience,  such as Nonlinear Dynamics, Shipping and  other Offshore Engineering fields.