SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Implementing a gaussian process learning algorithm in mixed parallel environment

In this paper, we present a scalability analysis of a parallel Gaussian process training algorithm to simultaneously analyze a massive number of time series. We study three different parallel implementations: using threads, MPI, and a hybrid implementation using threads and MPI. We compare the scalability for the multi-threaded implementation on three different hardware platforms: a Mac desktop with two quad-core Intel Xeon processors (16 virtual cores), a Linux cluster node with four quad-core 2.3 GHz AMD Opteron processors, and SGI Altix ICE 8200 cluster node with two quad-core Intel Xeon processors (16 virtual cores). We also study the scalability of the MPI based and the hybrid MPI and thread based implementations on the SGI cluster with 128 nodes (2048 cores). Experimental results show that the hybrid implementation scales better than the multi-threaded and MPI based implementations. The application of the proposed algorithm is demonstrated in analyzing massive remote sensing observation data. The hybrid implementation, using 1536 cores, can analyze a data set with over 4 million time series in nearly 5 seconds while the serial algorithm takes nearly 12 hours to process the same data set.
DIGITISATION OF PROCESSES AND MANAGEMENT CONTROL FOR ASSOCIATED MACO STUDIOS

THE PROJECT PRESENTED BY STUDIO MACO ASSOCIATI AND AIMED AT PROMOTING THE DEVELOPMENT, THE STRUCTURING OF THE ACTIVITIES OF THE STUDIO AND THE STRATEGIC REPOSITIONING OF THE SAME, THANKS TO THE INTRODUCTION OF COMPUTER SYSTEMS THAT ALLOW A MANAGEMENT
DISPERSION SPUN FLUOROPOLYMER FIBER PREPARED FROM NON-MELT-PROCESSIBLE POLYTETRAFLUOROETHYLENE AND PERFLUOROALKOXY

A dispersion spun fluoropolymer fiber prepared from non-melt-processible polytetrafluoroethylene particles and perfluoroalkoxy particles.
An Overview of the Homeschooling in Brazil: Analysis of Its Principles and Attempts of Legalization

Homeschooling is a kind of education that is growing. The goal of this study is to review issues used against attempts to legalize homeschooling in Brazil, which have brought up questions about what the right to education is. It presents some themes and concepts of the New Institutionalism Theory in Education as an attempt to relate them to the debate that goes around the growth of the homeschooling movement in different places as well as a context connected to the “concerted cultivation” concept. Thus, this paper suggests that emergence of homeschooling in Brazil is not associated to the school choice movement, but to the growth of concerted cultivation and represents for the country a movement with strong political implications.
Validation and optimization of an open-source novel nonlinear froude-krylov model for advanced design of wave energy converters

Wave energy represents a great untapped potential, but modern technologies are not economically viable yet, mainly due to high investment risk and modelling uncertainties during design/development stages. Accurate and computationally fast mathematical models are essential tools for effectively and reliably designing wave energy converters (WECs). Although WEC dynamics are typically very nonlinear, linear (imprecise) models are extensively used due to their computational convenience; in contrast, nonlinear models currently available are more accurate but too slow for design optimisation or control applications. 

This fellowship purports to develop, validate, and disseminate a novel class of nonlinear models, which will realise an unprecedented pairing of accuracy and computational speed (100 to 1000 times faster than homologous existing models). Conversely to other, slower nonlinear models, this novel model can facilitate effective design and optimisation of the device, enable real-time power optimisation and model-based control. The project will greatly impact the wave energy community, making a high-performance modelling tool easily accessible to any stakeholder for a variety of advanced design purposes. This project is comprised of 3 work packages, which accomplish: (1) validation of the model for axisymmetric devices, (2) expansion and validation of the model for pitching platform devices, and (3) enhancement of computation performance and release of an open-source software. In addition, this fellowship will expand the career horizons of the fellow: a highly multidisciplinary plan is defined, building upon and extending beyond his current competencies. The fellow is well-positioned to undertake this project, allowing him to fully develop innovative ideas from his PhD research. This fellowship will provide the fellow with an unparalleled opportunity to grow as a scientist and engineer, launching him on a trajectory to a productive and rewarding scientific career.
A sustainable organic solution for bees decline

With 630.000 beekeepers and 16 millions of hives, the apiculture sector is an important part of the EU agriculture. In addition, honeybees play the crucial ecosystem service of pollination, guaranteeing also the maintenance of the biodiversity. However, since a few decades, apiculture is facing important losses.However, since a few decades, apiculture is facing important losses due to abiotic and biotic factors. American foulbrood (AFB), caused by the spore-forming Paenibacillus larvae ssp. larvae is the most 
The project aims to tackle the global bee health challenge by developing a feasibility study for MICRO4BEE, an eco-innovative product representing a sustainable solution to decline of bees caused by bacteriological diseases. 
The product is patented by Micro4yoU, a company transferring research results into the development of innovative microbial-based green technologies and seizing National, European and global business opportunities. 
In Europe, no products are on the market to fight against bacterial pathogens and MICRO4BEE meets an urgent market need: it may achieve a high level of approval from beekeepers, for whom to date the only possible response to these diseases is to destroy the hives. 
MICRO4BEE represents an innovative product composed of a mix of symbiotic bacteria, naturally present in the gut of bees, harmless to humans and with probiotic activities towards honeybees. Although first target customers are organic producers (aprox. 10%-15% of beekeepers), due to the lack of valid chemical alternatives also non-organic producers are an interesting market segment, at EU and global markets level. 
The feasibility study will cover regulatory, market, economic and financial analysis,  the refinement of the IP management strategy and the operative options associated to the product design. The business plan developed will be used to search for business partners, including private co-investors and commercial partners with significant EU/worldwide network.
Brevíssimas considerações históricas sobre o processo de vacinação de crianças e adolescentes contra a COVID-19 no Brasil

Segundo a Organização Mundial da Saúde (OMS), o sobrepeso e a obesidade podem ser definidas enquanto o acúmulo anormal ou excessivo de gordura, podendo se constituir enquanto prejudiais a saúde.1 Os referidos problemas de saúde pública tem adquirido proporções pandêmicas, onde aproximadamente, 4 milhões de pessoas morrem a cada ano em sua decorrência ou por conta de complicações relacionadas.
Modeling Actin Dynamics

The field of actin dynamics has been blessed with a wealth of quantitative experimental data, which has motivated the development of computational models. The models allow researchers to understand how all the components of the system fit together to support diverse cell biological functions. This article presents a number of these models to exemplify different modeling approaches and philosophies. The material is intended for both physicists who wish an introduction to the actin field and cell biologists looking for an introduction to how modelers think about a problem. Despite the selective choice of examples, the article serves as an overview of the current state of the field of actin dynamics.
Optimization of the electromechanical systems on the basis of coupled field‐circuit approach

Purpose – The purpose of this paper is to present an algorithm of the optimization of the dynamic parameters of an electromagnetic linear actuator operating in error‐actuated control system.Design/methodology/approach – The elaborated “unaided” software consists of two main parts: optimization solver and numerical model of the actuator. Genetic algorithm has been used for optimization. The coupled field‐circuit‐mechanical model for the simulation of the system dynamics has been applied. Different optimization problems have been considered. The shape of the steady‐state force‐displacement actuator characteristic has been imposed and its deviation has been minimised. Next, the total operation time of the actuator without feedback, and the setup time of the actuator with feedback are minimised. Finally, required trajectory of movement has been imposed and trajectory error is minimised.Findings – The elaborated algorithm and the computer code can be an effective tool for field‐circuit simulation of the dynami...
Kalman Filter with Augmented Measurement Model: An ECG Imaging Simulation Study

ECG imaging is a non-invasive technique of characterizing the electrical activity and the corresponding excitation conduction of the heart using body surface ECG. The method may provide great opportunities in the planning of cardiac interventions and in the diagnosis of cardiac diseases. This work introduces an algorithm for the imaging of transmembrane voltages that is based on a Kalman filter with an augmented measurement model. In the latter, a regularization term is integrated as additional measurement. The filter is trained using a-priori-knowledge from a simulation model. Two effects are investigated: the influence of the training data on the reconstruction quality and the representation of a-priori knowledge in the trained covariance matrices. The proposed algorithm shows a promising quality of reconstruction and may be used in the future to introduce generic physiological knowledge in solutions of cardiac source imaging.
OSU-03012 suppresses GRP78/BiP expression that causes PERK-dependent increases in tumor cell killing

We have further defined mechanism(s) by which the drug OSU-03012 (OSU) kills tumor cells. OSU lethality was suppressed by knock down of PERK and enhanced by knock down of ATF6 and IRE1α. OSU treatment suppressed expression of the chaperone, BiP/GRP78, and did so through reduced stability of the protein. Knock down of BiP/GRP78 further enhanced OSU lethality. Overexpression of BiP/GRP78 abolished OSU toxicity. Pre-treatment of cells with OSU enhanced radiosensitivity to a greater extent than concomitant or sequential drug treatment with radiation exposure. Expression of a mutant active p110 PI3K, or mutant active forms of the EGFR in GBM cells did not differentially suppress OSU killing. In contrast loss of PTEN function reduced OSU lethality, without altering AKT, p70 S6K or mTOR activity, or the drug's ability to radiosensitize GBM cells. Knock down of PTEN protected cells from OSU and radiation treatment whereas re-expression of PTEN facilitated drug lethality and radiosensitization. In a dose-dependent fashion OSU prolonged the survival of mice carrying GBM tumors and interacted with radiotherapy to further prolong survival. Collectively, our data show that reduced BiP/GRP78 levels play a key role in OSU-3012 toxicity in GBM cells, and that this drug has in vivo activity against an invasive primary human GBM isolate.
METHODS AND APPARATUS FOR DATA STORAGE ON MAGNETIC MEDIA INCLUDING ERROR CORRECTION CODES

In a digital data storage system providing two or more levels of interleaved Reed-Solomon error correction coding together with a track checksum, the track checksum is calculated according to an algorithm which has no correlation with the Reed-Solomon codeword generation rules. This allows miscorrections at the C2 correction level to be determined reliably thereby enhancing the correction rate. Also disclosed is a system which uses the enhanced ability to identify C2 miscorrections, to mark C2 miscorrections to the third level of error correction thereby allowing double error correct at the third level.
HIGH EFFICIENCY AND HIGH CAPACITY FILTER MEDIA

A high efficiency and high capacity filter medium (10) including a top layer of fibrous felt material (12), an intermediate layer of melt-blown material (14), and a substrate layer (16) needled together into an integrated layer of filter material. The substrate layer (16) is formed of a layer of composite fiber including a group of melt-blown fibers interspersed between groups of spun-bonded fibers. Alternatively, the substrate layer is formed of spun-bonded material.
Tattooing of skin results in transportation and light-induced decomposition of tattoo pigments â a first quantification in vivo using a mouse model

Millions of people are tattooed with inks that contain azo pigments. The pigments contained in tattoo inks are manufactured for other uses with no established history of safe use in humans and are injected into the skin at high densities (2.5 mg/cm(2)). Tattoo pigments disseminate after tattooing throughout the human body and although some may photodecompose at the injection site by solar or laser light exposure, the extent of transport or photodecomposition under in vivo conditions remains currently unknown. We investigated the transport and photodecomposition of the widely used tattoo Pigment Red 22 (PR 22) following tattooing into SKH-1 mice. The pigment was extracted quantitatively at different times after tattooing. One day after tattooing, the pigment concentration was 186 microg/cm(2) skin. After 42 days, the amount of PR 22 in the skin has decreased by about 32% of the initial value. Exposure of the tattooed skin, 42 days after tattooing, to laser light reduced the amount of PR 22 by about 51% as compared to skin not exposed to laser light. A part of this reduction is as a result of photodecomposition of PR 22 as shown by the detection of corresponding hazardous aromatic amines. Irradiation with solar radiation simulator for 32 days caused a pigment reduction of about 60% and we again assume pigment decomposition in the skin. This study is the first quantitative estimate of the amount of tattoo pigments transported from the skin into the body or decomposed by solar or laser radiation.
With data-driven modelling towards a successful energy transition

The power grid is an integral part of the power system. It connects all electrical consumers with generators and powers everything from household appliances to large factory machinery. Without this grid, farmers would not be able to feed their animals, car factories would come to a halt, mobile phone systems would fail and many of us would not even be able to make a cup of tea. While the current power system is very reliable and offers a high quality of service, it remains unclear how this will develop in the future. The limited supply of fossil fuels as well as necessary reduction of CO2 emissions to mitigate climate change, will eventually lead to a power grid mainly supplied by renewable generators, such as wind and solar plants. These plants output smaller total power so that a large number is necessary which have to be geographically distributed for optimal weather conditions. The current power grid system slowly emerged within several decades of optimization processes. However, now we are discussing how to revolutionize the whole energy system within years. Therefore, a fundamental understanding of the current power system is necessary to develop potential pathways to a future 100% sustainable system. In the proposed research, I will use data-driven approaches to work towards a quantitative understanding of fluctuations in the power grid, as they are for example introduced by the changing demand or volatile energy generation. I will analyse the British as well as international grids to understand differences in grid operation and potential solutions for grids. A key goal of the proposed project is to offer a data base of these measurements for the scientific community to analyse and to add to. Within this project, I will also develop analysis tools to be used by the scientific community as well as interested companies or government agencies.
Mulheres imigrantes no trabalho doméstico remunerado em São Paulo: duas trajetórias e uma multiplicidade de arranjos

Resumo Este trabalho busca articular os temas das migrações internacionais de mulheres e do trabalho doméstico remunerado. Especificamente, nossa atenção se volta às trajetórias de duas imigrantes trabalhadoras domésticas na cidade de São Paulo. Partimos do pressuposto de que cada imigrante é um sujeito coletivo, representante (também) de grupos sociais, razão pela qual suas trajetórias são ilustrativas da diversidade de arranjos familiares, migratórios e laborais que podem existir. Além disso, buscamos ressaltar os fatores macroestruturais contextuais da origem de cada uma, bem como suas próprias percepções sobre as oportunidades que possuem e suas aspirações. Para a realização desta pesquisa, foi feita revisão bibliográfica e documental de dados secundários, além de entrevista semiestruturada com cada interlocutora. Objetivamos, assim, salientar a multiplicidade de experiências e subjetividades, as transformações em curso quanto aos sujeitos envolvidos no trabalho doméstico e na imigração no Brasil.
Traços biográficos de Ethel Parsons: uma liderança na enfermagem norte-americana e brasileira

RESUMO Objetivo: reconstruir aspectos biográficos de Ethel Parsons no centenário da missão de cooperação técnica para o desenvolvimento da enfermagem no Brasil. Método: pesquisa biográfica, realizada pelo método de análise de fontes históricas, que consiste em leitura e interpretação dos documentos coletados. Resultados: de família renomada, Ethel Parsons ocupou chefias de serviços de saúde pública e atuou na Cruz Vermelha Americana antes de ser indicada para coordenar a missão da Fundação Rockefeller no Brasil, onde inaugurou o modelo anglo-americano de enfermagem. Por dez anos, Parsons se dedicou a liderar tal missão, que resultou na implantação e difusão, por força de decreto, do modelo anglo-americano de enfermagem. Em 1931, retornou a seu país, onde faleceu em 1953. Conclusão: Ethel Parsons se destacou no século XX como mulher e enfermeira, liderando serviços assistenciais de saúde pública nos EUA e no Brasil. Sua biografia demonstra um ideal de profissionalização e ciência a ser conquistado pela enfermagem no cenário assistencial e educacional, que influenciou no delineamento de uma identidade coletiva da enfermagem brasileira.
Boosting 4 best practices for soil health in europe

Healthy soils are of major importance for the future of the European horticultural and agricultural crop production. Especially in intensive production systems, soilborne diseases are a major factor with a negative impact on soil health. Newly developed best practices and sound crop rotations permit to maintain, improve or re-establish soil health in Europe.
The BEST4SOIL project will build a community of practice network across Europe by inter-connecting growers, advisers, educators and researchers. Through this network, knowledge ready for practice on 4 best practices for the control of soilborne diseases (compost/organic amendments; green manures/cover crops; anaerobic soil disinfestation (ASD); and (bio)solarisation) will be promoted. Open-access databases with information on the range of pathogens affecting host plants will help the practitioners to build appropriate crop rotations and innovative control strategies.
As innovative tool will BEST4SOIL provide tutorial videos (youtube), easily understandable also to growers with limited language skills. Videos, databases and factsheets are edited in 22 official EU languages to facilitate the innovation management of practitioners throughout Europe. The information will be freely accessible and highly comprehensible to guarantee a smooth knowledge transfer from research to practice. BEST4SOIL will deploy local facilitators to set up a network with active communities of practice resulting in an intensive knowledge exchange.
The consortium of BEST4SOIL includes advisers, breeder, communicators, educators, growers, and researchers from eight European countries. Together with facilitators in at least twelve more countries, the network will interconnect an important part of the European growers, advisers and educators, the main stakeholders of BEST4SOIL.
https://www.7reasons.net/?page_id=37758
The Relationship Between Age and Perioperative Complications

With the continuous rise in life expectancy, the geriatric population has come to account for more than a third of all inpatient surgical procedures. This number will undoubtedly continue to rise over the next two decades. The geriatric population is at an increased risk of perioperative complications, and therefore, the elderly deserve special attention in the perioperative period. Ideally, this should commence upon initial consultation. A thorough history and physical exam can help stratify the patient risk factors and identify which patients require further preoperative testing. Consultations with other providers should be obtained as needed. In the operating room and postoperatively, each patient should receive individualized care tailored according to his/her preoperative work-up. In this paper, we review the steps that should be taken to minimize the risk of perioperative complications in the elderly.
Interannual variability of Pacific Winter Water inflow through Barrow Canyon from 2000 to 2006

We examined the interannual variability of Pacific Winter Water (PWW), both upstream in the northeastern Chukchi Sea and Barrow Canyon using mooring observations from 2000 to 2006, and downstream in the Canada Basin using hydrographic data acquired in 2002–2006. The interannual variation of PWW salinity is governed by two factors: (1) variability in the salinity of Pacific Water that flows northward through Bering Strait in winter; and (2) the input of salt associated with sea ice formation during winter in an intermittent coastal polynya located along the Alaskan coast between Cape Lisburne and Point Barrow. During the winters of 2000/2001 and 2001/2002 an increased transport of cold and saline PWW (S > 33.5) to the basin via Barrow Canyon was observed. In 2000/2001 enhanced ice formation in the polynya contributed to the increased salinity of PWW, whereas in 2001/2002 the salinity of water entering through the Bering Strait was higher, and this resulted in more saline PWW being delivered to the basin. In the following four winters (2002/2003, 2003/2004, 2004/2005 and 2005/2006) the transport of cold and saline PWW in winter to the basin was less than that in the two preceding winters. In three of these four winters (2003/2004 being the exception) the coastal polynya was less active, thus reducing the input of salt due to brine enrichment. In the winter of 2003/2004, however, warmer water within the polynya region constrained ice formation and thus less cold and saline PWW was produced, despite the fact that the coastal polynya was active and frequently open.