SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
The effectiveness of psychodynamic psychotherapies: An update

This paper provides a comprehensive review of outcome studies and meta-analyses of effectiveness studies of psychodynamic therapy (PDT) for the major categories of mental disorders. Comparisons with inactive controls (waitlist, treatment as usual and placebo) generally but by no means invariably show PDT to be effective for depression, some anxiety disorders, eating disorders and somatic disorders. There is little evidence to support its implementation for post-traumatic stress disorder, obsessive-compulsive disorder, bulimia nervosa, cocaine dependence or psychosis. The strongest current evidence base supports relatively long-term psychodynamic treatment of some personality disorders, particularly borderline personality disorder. Comparisons with active treatments rarely identify PDT as superior to control interventions and studies are generally not appropriately designed to provide tests of statistical equivalence. Studies that demonstrate inferiority of PDT to alternatives exist, but are small in number and often questionable in design. Reviews of the field appear to be subject to allegiance effects. The present review recommends abandoning the inherently conservative strategy of comparing heterogeneous "families" of therapies for heterogeneous diagnostic groups. Instead, it advocates using the opportunities provided by bioscience and computational psychiatry to creatively explore and assess the value of protocol-directed combinations of specific treatment components to address the key problems of individual patients.
New Models of Innovation for Strategic Cluster Partnerships

New models of innovation are needed because globalization and digitalization cause rapidly changing value chains and business models. Policy makers need to learn about such new models to keep the pace and be able to provide fast and flexible support for emerging industries in order to make/keep a region competitive at global scale. 
ClusteriX 2.0 aims to improve policy instruments related to the actual delivery of innovation making better use of clusters to facilitate such processes by focusing on complementary competences, by introducing new models of innovation for the development and operational implementation of strategic cluster partnerships. 
Our goal is to increase the number of collaborations between enterprises and knowledge institutions (by 5 % on average by 2020) leading to new value chains through cross-cluster collaboration and eventually to new products and solutions. This shall be done by improving policy instruments related to networking, clusters and open innovation through smart specialization.
As sub-objectives we intend to increase the number of cross-sector collaborations and cluster partnerships within each partner region and to develop strategic interregional partnerships based on complementary competences identified through smart regional profiling.
The main outputs are 81 policy learning events organized, minimum 20 good practices identified, analysed and shared, 10 action plans developed and implemented and minimum 50 appearances in media.
Direct beneficiaries are at least 50 people from Managing Authorities/Intermediate Bodies, implementing organizations, and various local/regional/national stakeholders with increased professional capacity benefiting from the interregional exchange.  Through improved policy instruments (9 Structural Funds, 1 regional) enterprises, research institutes and other innovation actors in the region benefit indirectly from ClusteriX 2.0.
A preliminary 1‐D model investigation of tidal variations of temperature and chlorinity at the Grotto mound, Endeavour Segment, Juan de Fuca Ridge

Tidal oscillations of venting temperature and chlorinity have been observed in the long-term time series data recorded by the Benthic and Resistivity Sensors (BARS) at the Grotto mound on the Juan de Fuca Ridge. In this study, we use a one-dimensional two-layer poroelastic model to conduct a preliminary investigation of three hypothetical scenarios in which seafloor tidal loading can modulate the venting temperature and chlorinity at Grotto through the mechanisms of subsurface tidal mixing and/or subsurface tidal pumping. For the first scenario, our results demonstrate that it is unlikely for subsurface tidal mixing to cause coupled tidal oscillations in venting temperature and chlorinity of the observed amplitudes. For the second scenario, the model results suggest that it is plausible that the tidal oscillations in venting temperature and chlorinity are decoupled with the former caused by subsurface tidal pumping and the latter caused by subsurface tidal mixing, although the mixing depth is not well constrained. For the third scenario, our results suggest that it is plausible for subsurface tidal pumping to cause coupled tidal oscillations in venting temperature and chlorinity. In this case, the observed tidal phase lag between venting temperature and chlorinity is close to the poroelastic model prediction if brine storage occurs throughout the upflow zone under the premise that layers 2A and 2B have similar crustal permeabilities. However, the predicted phase lag is poorly constrained if brine storage is limited to layer 2B as would be expected when its crustal permeability is much smaller than that of layer 2A.
IRON(III) FORMULATIONS FOR THE TREATMENT OF GASTROINTESTINAL INFLAMMATION

The present invention relates to an iron-based formulation and compositions thereof for use in a method for the treatment of a gastrointestinal inflammation, in a therapeutic or non-therapeutic treatment of an iron deficiency by administering said formulation to a subject, wherein said iron formulation is capable of reducing (or maintaining constant) the amount of pathogenic bacteria present in the gut microbiota of the treated subject and, preferably, also capable of increasing the variety of the gut microbiota of the treated subject.
Produksi dan Fisiologi Kedelai pada Kondisi Cekaman Kekeringan dengan Aplikasi Bradyrhizobium japonicum yang Diberi Penginduksi Genistein

ABSTRACT Mutualism symbiosis between B. japonicum and soybean root is a complex case and managed by molecular signal exchange. Genistein is one of the main isoflavones in soybean root exudates which is responsive to nod gen induction in B. japonicum. Drought stress could give negative effect on the symbiosis. The aim of the research was to study the role of B. japonicum induced by genistein on production and physiological characters of soybean under drought stress. The experiment was conducted in a green house, Faculty of Agriculture, University of Sumatera Utara, using a randomized complete block design with three factors. The first factor was genistein induction, consisted of  with and without genistein. The second factor  was B. japonicum inoculation consisted of  without B. japonicum,  isolate 1, isolate 2 and isolate 3. The third factor  was soil water content condition, consisted of 40%, 60% and 80% of field capacity. The parameters observed were shoot dry weight, root dry weight,  net assimilation rate, dry weight per plant, 50 seeds weight and proline content. The result showed that increasing drought stress conditions decreased shoot dry weight, root dry weight, net assimilation rate, effective nodules number, seeds dry weight per plant and 50 seeds weight. The result showed that as an inducer of B. japonicum in drought stress condition, genistein reduced the effects of water stress on root nodulation of soybean. Proline acts as osmoregulator for increasing tolerance to drought stress in plants. Keywords: drought, genistein, soybean, root nodulation
TREATMENT APPARATUS WITH FLOWBACK FEATURE

A coiled adaptive seat is held to a smaller diameter for delivery with a tool that features a locating lug for desired alignment of the seat with an intended groove in the inner wall of a tubular. The release tool retracts a cover from the seat allowing its diameter to increase as it enters a groove. Alternatively the adaptive seat is released near the groove and pushed axially in the string to the groove for fixation. Once in the groove the inside diameter of the string is a support for a blocking object so that sequential treatment of parts of a zone can be accomplished. The blocking object is removed with pressure, dissolving, milling or disintegration leaving a narrow ledge in the tubular bore from the seat that can simply be left in place or milled as well. An E4#10 from Baker Hughes is modified for adaptive seat delivery.
ISOLASI DAN IDENTIFIKASI SENYAWA TOKSIK DARI TUMBUHAN Spigelia anthelmia Linn KOLEKSI DARI KAWASAN PANTAI SELATAN, KABUPATEN BANTUL, DAERAH ISTIMEWA YOGYAKARTA

Spigelia anthelmia Linn is a plant commonly found in the Pantai Selatan
area, the district of Bantul. Its use as a medicinal plant is still not widely known.
The purpose of this study is to search the bioactive compound using S. atnhelmia
Bioassay model isolation was done using BST (Brine shrimp Lethality test) and
the isolated compound to tested further on T47D breast cancer cells and colon
cancer cells WiDr.
The method extraction using maceration with dichloromethane followed
by methanol. Extracts obtained were fractionated using vacuum column
chromatography (VCC) silica gel 60 PF254. Active fraction was separated by
Preparative Thin Layer Chromatography (TLC Preparative) using silica gel 60
PF254 with mobile phase of chloroform: methanol (9: 1). Isolat A obtained was
evaluatd for its LC50 on the brine shrimp test. Isolate A was tasted on T47D
cancer and WiDr cells line. Isolat A was identified its structure with IR
(Infrared),Liquid Chromatography Mass Spectra (LCMS) C18 column (RP 18)
Phenomenex, and Mass Spectrometry (MS) system ESI (Electrospray Ionisation)
and NMR spectroscopy (Nuclear Magnetic Resonance).
Isolat A had LC50 17.08 ug/ml against Brine shrimp test. Isolat A
displayed LC50 value 166.92 ug / ml on T47D cells and 250.24 ug / ml in WiDr
cells. Isolat A showed 92.3% purity and has molecular weight at 218 m / z by
LCMS. IR data showed the presence of OH, carbonyl and amine groups. Data 1H
and 13C NMR spectroscopy showed isolat A has a phenol bonded carbocyclic
acids and pyrrolidine frame.
Understanding the anion–π interactions with tetraoxacalix[2]arene[2]triazine

Anion-π interaction is a new type of non-covalent interaction. It has attracted growing interest in recent years both theoretically and experimentally. However, the nature of bonding between an anion and an electron-deficient aromatic system has remained elusive. To understand the bonding nature in depth, we have carried out a systematic computational study, using model systems that involve tetraoxacalix[2]arene[2]triazine 1, an electron-deficient macrocyclic host, and four anions, X(-) (X(-) = SCN(-), NO3(-), BF4(-), and PF6(-)), of varied sizes and shapes. The geometries for the 1·X(-) complexes were optimized using the extended ONIOM (XO) method. The good agreements with the X-ray experimental results provide a validation of our theoretical schemes. The nature of the non-covalent interactions was analyzed with the help of the AIM (atoms in molecules), RDG (reduced density gradient) and LMO-EDA (local molecular orbital-energy decomposition analysis) methods. The results clearly reveal the involvement of anion-π bonding, as well as a weak, yet significant, hydrogen bonding interaction between the benzene C-H on 1 and the anion of NO3(-) or PF6(-). The bonding energies of 1·X(-) were calculated with the XYG3 functional, and the results were compared with those from MP2, M06-2X and some other functionals with non-covalent interaction corrections (e.g., B3LYP-D3, and ωB97X-D). We conclude that the binding strengths follow the order of 1·NO3(-) > 1·SCN(-) > 1·BF4(-) > 1·PF6(-), where the difference between 1·SCN(-) and 1·BF4(-) is less significant. The strongest interaction in 1·NO3(-) comes from: (1) the effective electronic interaction between NO3(-) and the triazine rings on 1; and (2) the weak hydrogen bonding interaction between the benzene C-H on 1 and nitrate, which cooperates with the anion-π interactions.
Empowering homecare solutions in advanced wound care

Due to an aging population with growing rates of obesity and diabetes, over 50M patients suffer from hard-to-heal wounds annually, which has created a severe cost burden to global healthcare systems. 
Piomic Medical AG, a Swiss Med-Tech company founded in 2016, develops a medical device to promote wound healing processes in hard-to-heal wounds. The device matches market mega-trends for portability and patient self-management. The patient may benefit from a faster healing process, reduced pain and inflammation as well as an improved treatment outcome. Early traction allowed Piomic to conduct a first in human clinical trial to evaluate safety and efficacy of its product and engage CE certification under MDD regulation.
The management team of Piomic consists of professionals with interdisciplinary knowledge in science and engineering, paired up with experts in regulatory affairs, life science and product development. We believe life shouldn't be defined by a medical condition. By developing a therapy which is safe and effective we hope to set a better future for everyone in need.
The feasibility study aims to validate the commercial feasibility of Piomic with target market segments and key stakeholders. We will strengthen our financial planning and IP protection strategy necessary to improve our service and refine our go-to-market strategy. We will also specify product features needed for a fully commercialized solution upgraded to TRL 9, after the SME Instrument Phase 2.
With a Total Addressable Market of €19.3 billion, we plan to reach €35m revenues by 2024 with 90+ FTEs employed.
Ultrasensitive chiral detection by signal-reversing cavity polarimetry: applications to in-situ proteomics, single-molecule chirality, hplc analysis, medical diagnostics, and atmospheric studies

Chirality is a fundamental property of life, making chiral sensing and analysis crucial to numerous scientific subfields of biology, chemistry, and medicine, and to the pharmaceutical, chemical, cosmetic, and food industries, constituting a market of 10s of billion €, and growing.
Despite the tremendous importance of chiral sensing, its application remains very limited, as chiroptical signals are typically very weak, preventing important biological and medical applications. Recently, the project-coordinating FORTH team has introduced a new form of Chiral-Cavity-based Polarimetry (CCP) for chiral sensing, which has three groundbreaking advantages compared to commercial instruments: (a) The chiroptical signals are enhanced by the number of cavity passes (typically ~1000); (b) otherwise limiting birefringent backgrounds are suppressed;
(c) rapid signal reversals give absolute polarimetry measurements, not requiring sample removal for a null-sample measurement. Together, these advantages allow improvement in chiral detection sensitivity by 3-6 orders of magnitude (depending on instrument complexity and price). ULTRACHIRAL aims to revolutionize existing applications of chiral sensing, but also to instigate important new domains which require sensitivities beyond current limits, including: (1) measuring protein structure in-situ, in solution, at surfaces, and within cells and membranes, thus realizing the “holy-grail” of proteomics; (2) coupling to high performance liquid chromatography (HPLC) for chiral identification of the components of complex mixtures, creating new standards for the pharmaceutical and chemical analysis industries; (3) chiral analysis of human bodily fluids as a diagnostic tool in medicine; (4) measurement of single-molecule chirality, by adapting CCP to microresonators, which have already demonstrated single-molecule detection; and (5) real-time chiral monitoring of terpene emissions from individual trees and forests, as a probe of forest ecology.
Enhancing India-Central Asia Engagement: Prospects and Issues

The Central Asian Nations have been undergoing the process of nation building for the last two decades. Within a short time they have made considerable progress in many areas of human endeavor. To take advantage of the rapidly globalizing world the Central Asian nations have been broadening their engagement with the Outside world. Indian engagement in with Central Asian countries is quiet desirable, India considers Central Asia as a part of its extended neighborhood. While security and stability in the region is of prime importance but economic engagement is the driving factor of the emerging relationship. This book is broadly built around the theme of security and stability enhancing economic engagement including the energy sector and increase connectivity to promote trade and commerce. This book contains many sub themes for widening the India-Central Asia engagement and the way ahead for Afghanistan.
Laboratorio di Fisica di Superficie — Percorso Ottico per la Ricerca sui Materiali II

SPL-MSB è un laboratorio ceco nell'infrastruttura di ricerca europea CERIC-ERIC. Si compone di due parti, la pista ottica per la scienza dei materiali (MSB) presso l'Elettra Synchrotron di Trieste e il Laboratorio di Fisica delle Superficie (SPL) a Praga. L'obiettivo principale del progetto è quello di aumentare la qualità internazionale della ricerca e il suo utilizzo, che colmeremo con l'attività di modernizzazione di grandi infrastrutture di ricerca nella Repubblica Ceca acquisendo un nuovo strumento Spettrometro fotoelettronico automatico per le misurazioni ad alta pressione.
Some acute phase reactants and cholesterol levels in serum of patient with Crimean-Congo haemorrhagic fever

The purpose of this study is to determine erythrocyte sedimentation rate (ESR), C - reactive protein (CRP), serum amyloid-A (SAA) and cholesterol levels in patients with Crimean-Congo Hemorrhagic Fever (CCHF) and determine the relationship of these parameters with the severity of disease. By polymerase chain reaction and enzyme-linked immunosorbent assay (ELISA) method 40 patients were diagnosed as CCHF and 39 volunteer without any systemic disease whose blood were taken and their serum separated. SAA, CRP and ESR were measured with ELISA, nephelometry and Mix-Rate x100 vital diagnostic device, respectively, in serum samples. High density lipoprotein (HDL), low density lipoprotein (LDL) and total cholesterol levels were determined by using autoanalyzer HDL, LDL and total cholesterol kit (Syncron LX20). Statistically significant difference was determined between patients and controls in terms of the levels of SAA, CRP, HDL, LDL and total cholesterol (p&lt;0.05). However, there was no significant difference between the groups in terms of the levels of ESR. In addition, neither SAA, CRP, ESR nor HDL, LDL and total cholesterol levels varied with the severity of disease in the cases assessed (p&gt;0.05). Using of CRP and SAA together might increase the sensitivity of diagnosis of CCHF infection. However, none of the parameters investigated in this study were found to be a proper marker of the prognosis in CCHF. Cholesterol levels were significantly decreased in patients with CCHF, which was suggested to be associated with the increased serum levels of SAA in the patient group.
SOUND-ABSORBING FABRIC

The invention relates to a sound-absorbing fabric comprising a glass fabric which is made from glass yarns that are coated with a thermoplastic material, with an opening factor of between 0.5 and 6 %.
Integrated E-ticketing System – Possibilities of Introduction in EU

Development of information and communication technologies changes the manner in which many industries and services operate. Those changes are concerning public transport as well. One of the ways public transport can be improved is the introduction of integrated e-ticketing. The point of integrated e-ticketing is combining various modes of transport with use of a single ticket. In principle, the integrated e-ticketing simplifies switching between various modes of transport, making public transport easier to use and thus more attractive to potential users. For more than a decade, integrated e-ticketing system has been one of the goals of EU transport policy; nonetheless, its current application remains limited. Author attempts, based on analysis of existing integrated e-ticketing systems, to show potential dangers and costs connected to introduction of such solutions, along with possible gains for all parties involved – both the travellers and organizations that provide the services.
Whole-heart chemical shift encoded water-fat MRI

To develop and evaluate a free-breathing chemical-shift-encoded (CSE) spoiled gradient-recalled echo (SPGR) technique for whole-heart water-fat imaging at 3 Tesla (T).We developed a three-dimensional (3D) multi-echo SPGR pulse sequence with electrocardiographic gating and navigator echoes and evaluated its performance at 3T in healthy volunteers (N = 6) and patients (N = 20). CSE-SPGR, 3D SPGR, and 3D balanced-SSFP with chemical fat saturation were compared in six healthy subjects with images evaluated for overall image quality, level of residual artifacts, and quality of fat suppression. A similar scoring system was used for the patient datasets.Images of diagnostic quality were acquired in all but one subject. CSE-SPGR performed similarly to SPGR with fat saturation, although it provided a more uniform fat suppression over the whole field of view. Balanced-SSFP performed worse than SPGR-based methods. In patients, CSE-SPGR produced excellent fat suppression near metal. Overall image quality was either good (7/20) or excellent (12/20) in all but one patient. There were significant artifacts in 5/20 clinical cases.CSE-SPGR is a promising technique for whole-heart water-fat imaging during free-breathing. The robust fat suppression in the water-only image could improve assessment of complex morphology at 3T and in the presence of off-resonance, with additional information contained in the fat-only image.
Evaluation and testing of RT-Java parameters on aJile aJ-80 real time embedded platform

The purpose of this work is the implementation of the program code that enables digital filtration on aJ-80 embedded JAVA processor. While working the implementation filter we need to provide the fastest calculation with the greatest accuracy. Next, it is almost always necessary for the results to be available after the same time from the sample upload. These matters determine the digital filtration as a problem called RT, which is the problem suitable for testing of the processor aJ-80 and its RT features. The work also describes the chosen task example, which examines RT features of this processor. We also mention the attained results and their evaluation. Based on the evaluation, the performance of the hardware program of the processor aJ-80 is very effective. In this respect, the product is recommended to use in many hard RT areas.
TRansnational Accelerator for a Cultural and Creative EcoSystem

Traces project aims to promote the creative entrepreneurship in Puglia and Western Greece regions and to strengthen the Creative and Cultural Small and Medium Enterprises, as a key contributor to competitiveness across all economic and social sectors. Traces aims to set-up a transnational accelerator for a Cultural and Creative EcoSystem, intended as a smart environment with customized and integrated incubation services that facilitate the economic exploitation of new ideas and foster the creation of new firms. Well-equipped and trained Local Ateliers will offer co-working spaces and a hands-on acceleration programme through a special academy to access start-up development and management skills. Creatives can find staff with the right mix of managerial and ICT skills and set up creative partnerships with High Education and Research institutions, businesses, public administrations.