SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
High performance seasonal solar energy latent heat thermal storage using low grade, low melting temperature metallic alloys

Energy storage technologies have long been a subject of great interest to both academia and industry. The aim of this project is to develop a novel, cost effective and high performance Latent Heat Thermal Energy Storage System (LHTESS) for seasonal accumulation of solar energy in increased quantities. The major barrier for currently used Phase Change Materials (PCMs, organic and hydrated salts) is their very low heat conduction coefficient, low density, chemical instability and tendency to sub-cooling. Such inferior thermo-physical properties result in the LHTESS having large dimensions and not having a capacity to provide the necessary rate of heat re-charge and discharge, even with highly developed heat exchangers. The new approach to overcome the above issues is the deployment of low grade, eutectic low melting temperature metallic alloys (ELMTAs). The ELMTAs are currently produced for application in other areas and have not been actively considered for the thermal energy accumulation with the exception of very limited studies. Their heat conduction is two orders of magnitude greater than that of conventional PCMs, they are stable and provide the thermal storage capacity which is 2-3 times greater per unit of volume. The project consists of both theoretical and experimental investigations. A range of low grade ELMTAs for application in LHTESS will be selected and Differential Scanning Calorimetry will be used to measure their thermal properties. Thermal cycling tests of such alloys will be conducted. Numerical investigations of heat transfer and flow in the LHTESS with ELMTAs will be performed. Experimental studies of heat transfer and flow in a laboratory prototype of the LHTESS with ELMTAs will be conducted. As outcomes of investigations, dimensionless heat transfer correlations will be derived and design recommendations for a practical  solar energy seasonal LHTESS with the low grade ELMTA will be produced for project industrial partner
SANDWICH OF ELECTRIC CONDUCTOR, CARBON COMPRISING ADHESION PROMOTER AND ELECTRICALLY INSULATING THERMAL CONDUCTOR

Mounting device (100) for mounting electronic components, wherein the mounting device (100) comprises an electrically conductive structure (102), an adhesion promoting structure (104), which comprises carbon,on the electrically conductive structure (102), and a thermally conductive and electrically insulating structure (106) on the adhesion promoting structure (104).
Steering and radiation effects in oriented crystals and their applications implementation into geant4

Crystalline structure is a unique environment for strong-field QED effects involving both high-energy charged particles and photons. A small piece of crystal material could be used as an intense source of X- and gamma-ray radiation, a positron source, a beam manipulation instrument, a compact detector and a compact wake-field accelerator as well. Consequently, a crystal could be useful for a wide range of applications in accelerator physics, high-energy frontier physics, nuclear physics, cosmic-ray detectors, dark matter search and radiation therapy.

The implementation of both physics of electromagnetic processes in oriented crystals and the design of specific applications of crystalline effects into Geant4 simulation toolkit as Extended Examples to bring them to a large scientific and industrial community and under a free Geant4 license is the main goal of the project.

The implementation of the following innovative applications into Geant4 will be mainly focused on:
1. Crystalline deflector to extract a charged particle beam from an accelerator (electron synchrotron, hadron collider) to supply fixed-target experiments by an intense low-emittance beam.
2. Crystalline source of intense coherent hard X-ray and gamma radiation, crystalline undulator.
3. Crystal-based hybrid positron source for both linear and circular e+e- colliders (ILC, FCC-ee) as well as for muon colliders.

The outgoing research phase of this MSCA-GF project at SLAC National Accelerator Laboratory as well as training at Stanford University and Google and participation in high-tech Silicon Valley exhibitions will bring the ER to a considerably higher level of competence. During the incoming phase at INFN Division of Ferrara supplemented by the secondments to DESY and IJClab the ER will finally reach his professional maturity and independence as well as will acquire a lot of new ideas to submit them as ERC proposals or to create high-tech startups and a lot of professional contacts to realize them.
Impact of asthma controller medications on medical and economic resource utilization in adult asthma patients

To compare asthma-related resource utilization, adherence and costs among adults prescribed asthma controller regimens.Medical and pharmacy claims from a US managed-care claims database were used to identify adults (18-56 years) initiating asthma controller therapy. Patients had 2 years continuous enrollment and ≥ 1 medical claims for asthma (ICD9: 493.xx) (January 2004 - March 2009). Asthma exacerbations, short-acting β-agonist (SABA) fills, adherence (MPR ≥ 0.80) and asthma-related costs were assessed for 1 year after the initial asthma controller medication claim. Separate logistic and negative binomial regression models for monotherapy and combination therapy were developed to examine the impact of controller therapy on outcomes.A total of 28 074 patients [inhaled corticosteroids (ICS) (26.3%), leukotriene modifiers (LM) (23.2%), ICS + long acting β-agonist (LABA) (48.5%), ICS + LM (2%)] were included. LM patients had lower odds of ≥ 6 SABA fills (OR(adj) = 0.83, 95% CI: 0.73-0.96) and lower rates of asthma exacerbations (RR(adj) = 0.82, 0.75-0.89) vs. ICS patients. Odds of ≥ 6 SABA fills were similar for ICS + LM vs. ICS + LABA (OR(adj) = 1.3, 0.96-1.76); the rate of asthma exacerbations was greater for ICS + LM compared with ICS + LABA (OR(adj) = 1.4, 1.2-1.6). The proportion adherent was greatest for LM (14.9%) and ICS + LABA (4.1%). LM patients had higher unadjusted pharmacy costs, but lower medical costs compared to ICS patients. For combination therapy, ICS + LM had higher unadjusted mean medical and pharmacy costs vs. ICS + LABA. Higher adjusted mean total costs in the post-index period were observed for LM vs. ICS patients ($837 vs. 684) and for ICS + LM vs. ICS + LABA patients ($1223 vs. 873).LM monotherapy was associated with lower medical costs but higher total costs resulting from greater treatment adherence. Conversely, higher costs for ICS + LM resulted from greater exacerbations compared to ICS + LABA despite similar adherence. Higher total costs with LM were due to drug costs. Precise utilization of the medications filled by patients could not be determined.
Sovranismo: Il Mito dell’Europa unita, da Carlo Magno ad Altiero Spinelli

Il mito dell’Europa unita è durato dalla caduta di Roma fino ai giorni nostri; ma di una vera unità europea si può parlare solo per il periodo carolingio, perché successivamente si sono formati gli Stati nazionali. La moderna ideologia mira a costruire uno Stato unitario per tutti i popoli d’Europa; ma ciascun popolo ha diritto ad una propria autodeterminazione e identità culturale, ed una fusione coattiva verrebbe a ledere i diritti fondamentali delle collettività nazionali.
Folding proteins at 500 ns/hour with Work Queue

Molecular modeling is a field that traditionally has large computational costs. Until recently, most simulation techniques relied on long trajectories, which inherently have poor scalability. A new class of methods is proposed that requires only a large number of short calculations, and for which minimal communication between computer nodes is required. We considered one of the more accurate variants called Accelerated Weighted Ensemble Dynamics (AWE) and for which distributed computing can be made efficient. We implemented AWE using the Work Queue framework for task management and applied it to an all atom protein model (Fip35 WW domain). We can run with excellent scalability by simultaneously utilizing heterogeneous resources from multiple computing platforms such as clouds (Amazon EC2, Microsoft Azure), dedicated clusters, grids, on multiple architectures (CPU/GPU, 32/64bit), and in a dynamic environment in which processes are regularly added or removed from the pool. This has allowed us to achieve an aggregate sampling rate of over 500 ns/hour. As a comparison, a single process typically achieves 0.1 ns/hour.
Coating device and process for a wet section of an apparatus for production of a material web

Process for application of a coating medium on a traveling material web that is one of paper and cardboard, the coating medium including at least one of a pasty medium and a liquid medium, wherein the process includes forming a material web in a wet section of a machine for one of paper and cardboard and guiding the material web which is still wet with a traveling, endless, carrier belt during application of a coating medium. The application of the coating medium includes transferring the coating medium from a roll-coating mechanism to at least one transfer belt onto the still wet material web. The coating medium is transferred from a surface of the at least one transfer belt moving in a direction of travel of the material web. The at least one transfer belt is a traveling, endless, air-permeable transfer belt which is guided by rolls. This Abstract is not intended to define the invention disclosed in the specification, nor intended to limit the scope of the invention in any way.
Cognitive plants through proactive self-learning hybrid digital twins

While the concept of digitalisation and Industry 4.0 is making rapid inroads into the European manufacturing sector, there are several aspects that can be still incorporated into the system which can strengthen the goal of optimal process operations. One such aspect to the digitalisation vision is the ""cognitive element"", where the process plants can learn from historical data and adapt to changes in the process while also being able to predict unwanted events in the operation before they happen. Through this project, COGNITWIN (Cognitive digital Twin), we aim to add the cognitive element to the existing process control systems and thus enabling their capability to self-organise and offer solutions to unpredicted behaviours.  

To achieve the objectives of the project, we have partnered with six industries and seven research groups from seven European nations, each of whom will bring their expertise in data analytics and pattern recognition which are going to be at the heart of the COGNITWIN solution platform. The set-up of the platform includes a sensor network that will continuously monitor and collect data from various plant processes and assets which will be stored at a database. This data will be used to develop a digital twin of the process and will also be used to develop models with cognitive capability for self-learning and predictive maintenance which will lead towards optimal plant operations.
  
The project builds on ideas and technologies that have been validated in controlled environments (TRL 5) to arrive at prototype demonstrations in operational environments (TRL 7). The COGNITWIN project results will be implemented to our industrial partner's processes to demonstrate the transition from TRL 5 to TRL 7. 

TRL – Technology Readiness Level
Evaluation of Proprotein Convertase Subtilisin/Kexin Type 9: Focus on Potential Clinical and Therapeutic Implications for Low-Density Lipoprotein Cholesterol Lowering

Reduction in low-density lipoprotein cholesterol (LDL-C) is associated with a decrease in coronary heart disease (CHD). Statins are currently the most effective medications for LDL-C lowering; however, there continues to be a residual risk for cardiovascular events. Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a protease that promotes LDL receptor degradation, leading to an increase in LDL-C blood levels. Patients with PCSK9 gain-of-function mutations can have up to a 20-fold increase in associated CHD compared with patients without these mutations. Conversely, patients with PCSK9 loss-of-function mutations can have up to an 88% reduction in CHD without any deficits in neurologic or physiologic functions. PCSK9 can be modulated by current antihyperlipidemic therapies. In particular, statins lead to an increase in PCSK9, which may attenuate their full lipid-lowering effects. These attributes have made PCSK9 inhibition a desirable target for future drug therapies. Current investigational modalities inhibiting PCSK9 will also be discussed.
Application of a RS- and GIS-based semi-quantitative approach (analytical hierarchy process – AHP) in landslide hazard risk assessment of the Shivkhola Watershed, Darjiling Himalaya

The present study deals with the application of analytical hierarchy process to prepare landslide hazard risk map of the Shivkhola Watershed applying remote sensing and geographic information system (GIS). Firstly, to integrate all the required thematic data layers and to prepare landslide susceptibility map, prioritised class rating value and prioritised factor rating value were obtained by developing couple-comparing matrix with a reasonable consistency and with the help of MATLAB software after Saaty. Three important risk factor/element maps, that is, weighted land use/land cover map, road contributing area map and settlement density map, were developed and their weighted linear combination was performed to prepare landslide risk exposure map. Then by integrating landslide susceptibility map and landslide risk exposure map, a classification was incorporated on ARC GIS Platform to prepare landslide hazard risk map. To evaluate the validity of the landslide hazard risk map, probability/chance of landslid...
Prognostic validation of a new classification system for extent of resection in glioblastoma: A report of the RANO <i>resect</i> group

Terminology to describe extent of resection in glioblastoma is inconsistent across clinical trials. A surgical classification system was previously proposed based upon residual contrast-enhancing (CE) tumor. We aimed to (1) explore the prognostic utility of the classification system and (2) define how much removed non-CE tumor translates into a survival benefit.The international RANO resect group retrospectively searched previously compiled databases from 7 neuro-oncological centers in the USA and Europe for patients with newly diagnosed glioblastoma per WHO 2021 classification. Clinical and volumetric information from pre- and postoperative MRI were collected.We collected 1,008 patients with newly diagnosed IDHwt glioblastoma. 744 IDHwt glioblastomas were treated with radiochemotherapy per EORTC-26981/22981 (TMZ/RT→TMZ) following surgery. Among these homogenously treated patients, lower absolute residual tumor volumes (in cm3) were favorably associated with outcome: patients with "maximal CE resection" (class 2) had superior outcome compared to patients with "submaximal CE resection" (class 3) or "biopsy" (class 4). Extensive resection of non-CE tumor (≤5 cm3 residual non-CE tumor) was associated with better survival among patients with complete CE resection, thus defining class 1 ("supramaximal CE resection"). The prognostic value of the resection classes was retained on multivariate analysis when adjusting for molecular and clinical markers.The proposed "RANO categories for extent of resection in glioblastoma" are highly prognostic and may serve for stratification within clinical trials. Removal of non-CE tumor beyond the CE tumor borders may translate into additional survival benefit, providing a rationale to explicitly denominate such "supramaximal CE resection."
Grey whale ( Eschrichtius robustus ) in Norwegian waters 2000 years ago

Abstract The modern distribution of the grey whale (Eschrichtius robustus) is restricted to the North Pacific Ocean, but during the Holocene it occurred also in the North Atlantic Ocean, perhaps as recently as the 17th century. In the western Atlantic, subfossil bones of 12 specimens of grey whale have previously been reported, whereas in the eastern Atlantic there are at least 25 subfossil remains of grey whale from the postglacial period, mostly from the Netherlands, along with one in Belgium, three in England and one in Sweden, ranging in age from approximately 10,000 to a few hundred years ago. Here we utilise a new method of identifying species from fragmentary bones, using collagen fingerprinting, to screen 373 cetacean remains from along the Norwegian coast, including the remains of at least one grey whale specimen dating to 1930–1750 years ago, which was recovered from Kringlevagen in the municipality of Solund (61°, 01″ N, 4°73″E). This find, confirmed by ancient DNA analysis, is the most northerly record of this locally extinct species and increases our understanding of grey whale palaeobiogeography in the North Atlantic.
(14508.17092020.172002577) LMINV

LIVE MULTIMEDIA S.R.L.? A MASS-BASED COMPANY THAT DEALS WITH FILM PRODUCTION, POST-PRODUCTION AND DISTRIBUTION, VIDEO AND TELEVISION PROGRAMS. SPECIALISED IN LIVE SHOOTING. THE PROPOSED INVESTMENT INVOLVES A RENEWAL AND FURTHER ACQUISITION OF MULTIMEDIA EQUIPMENT BY THE COMPANY E.G. CINEMA CAMERA, DRONES, MONITORS, SO? TO BE IN LINE WITH THE PI STANDARDS? ADVANCED IN THE INDUSTRY AND FURTHER INCREASE THE QUALITY? PRODUCTION AND POST-PRODUCTION. THE COSTS OF RENTING AND UTILITIES ARE ALSO INCLUDED AS INVESTMENT EXPENSES IN WORKING CAPITAL.
Active magnetorheological elastomers: from hierarchical composite materials to tailored instabilities

In recent years, there has been an increased effort by scientists to obtain new composite materials with extreme properties. Inspired by natural and biological processes, scientists have proposed the use of hierarchical architectures (i.e., assembly of structural components) spanning several length scales from nanometer to centimeter sizes. Depending each time on the desired properties of the composite material, optimization with respect to its stiffness, weight, density, toughness and other properties is carried out. In the present subject, the interest is in magneto-mechanical coupling and tailored instabilities. Hierarchical materials, such as magnetorheological elastomers (MREs) which combine magnetic particles (at the scale of nanometers and micrometers) embedded in a soft polymeric non-magnetic matrix, give rise to a coupled magneto-mechanical response at the macroscopic (order of millimeters and centimeters) scale when they are subjected to combined magneto-mechanical external stimuli. These composite materials can deform at very large strains due to the presence of the soft polymeric matrix without fracturing. From an unconventional point of view, a remarkable property of these materials is that while they can become unstable by combined magneto-mechanical loading, their response is well controlled in the post-instability regime. This, in turn, allows us to try to operate these materials in this critically stable region, similar to most biological systems. These instabilities can lead to extreme responses such as wrinkles (for haptic applications), actively controlled stiffness (for cell-growth) and acoustic properties with only marginal changes in the externally applied magnetic fields. Unlike the current modeling of hierarchical composites, MREs require the development of novel experimental techniques and advanced coupled nonlinear magneto-mechanical models in order to tailor the desired macroscopic instability response at finite strains.
Prediction of human actions: Expertise and task‐related effects on neural activation of the action observation network

The action observation network (AON) is supposed to play a crucial role when athletes anticipate the effect of others' actions in sports such as tennis. We used functional magnetic resonance imaging to explore whether motor expertise leads to a differential activation pattern within the AON during effect anticipation and whether spatial and motor anticipation tasks are associated with a differential activation pattern within the AON depending on participant expertise level. Expert (N=16) and novice (N=16) tennis players observed video clips depicting forehand strokes with the instruction to either indicate the predicted direction of ball flight (spatial anticipation) or to decide on an appropriate response to the observed action (motor anticipation). The experts performed better than novices on both tennis anticipation tasks, with the experts showing stronger neural activation in areas of the AON, namely, the superior parietal lobe, the intraparietal sulcus, the inferior frontal gyrus, and the cerebellum. When novices were contrasted with experts, motor anticipation resulted in stronger activation of the ventral premotor cortex, the supplementary motor area, and the superior parietal lobe than spatial anticipation task did. In experts, the comparison of motor and spatial anticipation revealed no increased activation. We suggest that the stronger activation of areas in the AON during the anticipation of action effects in experts reflects their use of the more fine-tuned motor representations they have acquired and improved during years of training. Furthermore, results suggest that the neural processing of different anticipation tasks depends on the expertise level.
The role of basic residues in the fragmentation process of the lysine rich cell-penetrating peptide TP10

Selective cleavage effect of basic residues in the fragmentation of short peptides has been studied intensively. In contrast, the role of basic residues in the degradation of large peptides, such as cell-penetrating peptides, is largely unknown. In this work, the fragmentation of a 21 residues cell-penetrating peptide TP10 containing four lysine residues was studied by collision-induced dissociation mass spectrometry and computation methods. The influence of lysine residues on amide bond cleavage and fragmentation products was investigated. The results revealed that the selective cleavage effect of lysine residue did not present when the adjacent lysine residues in TP10 were both protonated. The localized high positive charge density might be the reason of preventing the mobile proton from migrating to the amide bonds in this part of the peptide. In contrast, the mobile proton preferred to reside in the N-terminal part of TP10 which had less positive charge. This preference gave more information of the peptide sequence in the mass spectrometry study and was helpful for stabilizing the C-terminal part of TP10, in which the basic lysine residues were preserved and crucial to the cell-penetrating process.
DEVICE AND METHOD FOR INSPECTING A PLURALITY OF THREADS THAT ARE DISPOSED SIDE BY SIDE

The invention relates to a device for quality inspection of a plurality of threads (1) that are disposed side by side, for example on a warping reel. Said device comprises a sensor device, a control device (8) and a bus system for linking the sensor device with the control device (8). The inventive device is characterized in that a plurality of sensors are combined to a sensor device which inspects a plurality of threads (1) each at the same time and which is linked with the control device (8) via the bus system (6, 7). The invention also relates to a corresponding method which is characterized in that the sensor device is composed of a plurality of sensors which continuously inspect online a plurality of threads (1) with respect to their thread pull and generate a signal that is evaluated by the bus system (6, 7) and the control device (8).
METHOD FOR COATING ELECTRICAL CONTACTS

Disclosed is a method for coating electrical contacts (1) in order to protect the same from environmental factors such as corrosion, wear, or dirt while maintaining the electrical conductivity thereof. According to said method, a multilayer or an electrically conductive layer having a chemically functional surface is applied to the contact (1).