SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Resurrecting luca - engineering of rna-encoded cellular life using dual evolution and intergenomic transplantation

Modern cellular life strictly depends on DNA as genetic material. However, a large body of evidence infers the existence of a previous, more primitive biology in which RNA also stored information in cellular entities. Recreating a living cellular fossil representing this transition from an ancient RNA world to modern DNA-based life would fundamentally advance our understanding of our biology’s history, and enable us to explore its biological properties experimentally. However, the reengineering of existing molecular systems into a viable doppelganger of the Last Universal Common Ancestor (LUCA) or one of its precursors is extremely challenging.
 
I propose to use a novel, combined top-down and bottom-up approach to create a modern-day doppelganger of LUCA by engineering bacterial hybrids with core cellular functions encoded on RNA. Using Darwinian Evolution as driver, my team and I will prototype and refine synthetic RNA-replicons through alternating replication in both cell-free and intracellular environments. This “dual evolution” approach will shape increasingly complex RNA networks capable of encoding complex genetic information. Following this, we will use these networks to create information-rich RNA chromosomes, enabling the transfer of essential genomic information from DNA to RNA. Finally, we will address this intergenomic transplantation by combining a novel RNA-delivery strategy with iterative rounds of genome deletion and complementation using state-of-the art CRISPR-Cas9 assisted genome editing.

The proposed research will fundamentally advance synthetic biology, and could positively answer the transformative questions: Can we create, program and evolve life-like systems that can survive in both cell-free and intracellular environments? Can we use these entities to construct an alternative biology in which central cellular activities are encoded on genomes not made of DNA?
MULTIAGENT SYSTEM FOR MONITORING POLARITY IN SOCIAL MEDIA BASED ON AN AGR MODEL

The strategy according to the invention for analysing polarity in texts includes a hybrid method for symbolic approximation, based on lexicons, with approximation based on automatic learning methods, the model of which is based on a dictionary of classified words with Python implementation of a system prototype for creating a lexicon.
Modernisierung und Erweiterung der Produktion

Ziel des Projekts ist es, die Produktion in der Produktions- und Montagehalle zu erweitern und zu modernisieren. Der Ausbau und die Modernisierung der Produktionsanlagen werden die Leistungsfähigkeit und Wettbewerbsfähigkeit in der Region steigern und gleichzeitig die Position des Unternehmens auf dem Arbeitsmarkt verbessern und damit die Zahl der Arbeitsplätze erhalten und erhöhen.
Fuel pump for high-pressure fuel injection system

A fuel pump for a high-pressure fuel injection system includes a high-pressure fuel pump 4 for supplying high-pressure fuel to injectors 8 for injecting high-pressure fuel into cylinders of an engine, a pressure control valve 10 for controlling the fuel pressure of the high-pressure fuel pump 4, a high-pressure fuel supply pipe 16 connecting the high-pressure fuel pump 4 and the injectors 8, a high-pressure fuel control pipe 17 connecting the injectors 8 and the pressure control valve 10, and a pump-control valve communication passage 18 formed to communicate the high-pressure fuel pump 4 with the pressure control valve 10 and bypass the injectors 8, the sectional area of the pump-control valve communication passage 18 being smaller than those of the high-pressure fuel supply pipe 16 and the high-pressure fuel control pipe 17. Owing to the provision of the pump-control valve communication passage 18, the high-pressure fuel pump of the fuel pump for a high-pressure fuel injection system can secure a pressure relief function without separate installation a relief valve.
Deep earth mantle phase transition maps: studied by time-resolved experiments

Processes in Earth's lower mantle govern our planet's inner dynamics and control surface plate tectonics. As such, a quantitative understanding of the physical and chemical properties of the lower mantle is pivotal to model Earth’s dynamic evolution, including the long-term chemical interactions between mantle and atmosphere that are vital to the development of habitability on Earth, and possibly other planets. While seismic tomography is providing increasingly detailed three-dimensional maps of the lower mantle, the interpretation of tomographic models to elucidate key factors such as mantle geochemical heterogeneity or dynamic mantle flow processes has proven to be highly ambiguous. 

All evidence points to phase transitions being the missing link needed to converge to a consistent interpretation of seismic observations. The same phase transitions also play a key role in governing mantle dynamics. But even fundamental properties, such as the location of major phase transition boundaries in Earth’s mantle, are poorly constrained. This is because the parameter space (pressure-temperature-composition) is huge and experimental measurements at planetary interior conditions are extremely slow.   

DEEP-MAPS will employ a novel class of time-resolved high-pressure/-temperature experiments that reduce by several orders of magnitude the time for key experiments. This will allow DEEP-MAPS to map lower mantle phase transitions, their impact on physical properties and their seismic signature with practically continuous coverage in relevant pressure-temperature-composition-space. DEEP-MAPS will further probe the time-dependence of phase transitions, transforming our understanding of how to scale from laboratory measurements to geophysical processes.

DEEP-MAPS will provide a step-change in our ability to interpret mantle seismic observables and to quantify the geodynamic impact of mantle phase transitions, ultimately leading to a holistic picture of Earth’s deep mantle.
A non-volatile microcontroller with integrated floating-gate transistors

We present a non-volatile processor architecture where its entire state can be almost instantly stored and restored in a non-volatile fashion. This capability is attractive for embedded or mobile devices in highly energy constrained environments. The non-volatile microprocessor can enable long computations to continue across power interruptions on self-powered devices or save idle power consumption without sacrificing responsiveness. To realize this vision, a microprocessor must be able to copy state between volatile and non-volatile storage with minimal latency and energy consumption. Our non-volatile architecture addresses this challenge through a per-cell integration of floating-gate non-volatile transistors into volatile state elements and careful system-level optimizations to hide expensive non-volatile operations. We evaluate this approach with a transistor-level prototype of an 8-bit nonvolatile microcontroller. Experiments indicate that the proposed architecture has minimal impact on normal operation while enabling all processor state to be preserved across an unexpected power interruption.
Cultural tourism based on Giuseppe Tartini

The common challenge faced by the project is the preservation of cultural heritage in the area around the border, with the aim of promoting the study, preservation and promotion of the cultural heritage, in connection with Giuseppe Tartini, a well-known musician born in Piran in 1692, as well as its enhancement in order to develop a new cross-border sustainable cultural tourism pathway. Tartini’s activities developed between Piran, Capodistria, Venice and Padua, and fascinated and influenced a huge part of the European cultural environment.
Exploring the impact of social mobilization on cooperation in community-based natural resource management systems: insights from water conflicts in spain and mexico

Environmental conflicts and related social movements can, under some conditions, help to improve the management of natural resources at local levels; we do not know yet, however, what those conditions are. This project uses social movement and common-pool resource theories to address this gap. For this purpose, the project builds on the work of environmental justice scholars pointing to the uniqueness of socio-environmental movements that involve the participation of local resource-dependent communities. 
This is a project of substantial policy relevance. Environmental justice conflicts are an endemic phenomenon in our societies, with more than 1200 instances registered across the world. Many of those conflicts have great potential to improve natural resource management or just the opposite depending on how they are treated. Most importantly, there is an international consensus about the benefits of decentralized management and community stewardship for socio-ecological sustainability; however, such stewardship faces problems of cooperation and institutional failure. The study will shed light on the role of social movements in helping communities with these problems.
Objectives and methods of the project include: 1) a meta-analysis of environmental justice movements in Spain and Mexico to explore variation in movements’ activities and membership across environmental and governance contexts; 2) a comparative case study of irrigation communities in the Yaqui and Ebro valleys (Mexico and Spain) to explore whether the impact of social mobilization on cooperative management varies depending on the type of leadership and discourses used to mobilize communities, the mobilization activities, and the movements’ membership; 3) a new model that integrates mobilization and cooperation to better understand community-based natural resource management; and 4) policy recommendations vis a vis the integration of conflict resolution and resource management policies at local levels.
Boosting energy fficiency in Central European cities through smart energy management

CE has a high potential in deployment of local and regional energy systems based on renewable energy generation and energy conservation but it is important to trigger bottom up initiatives improving energy efficiency approach at these levels. Reasonable energy consumption are fundamental if the targets of the EU’s 2020 strategy are to be reached in CE area. Large attention is being paid to improve EE of existing buildings as they are accountable for large electric power consumption with an annual growth rate of ca 4%.  A rapid transition of urban areas towards EE and adaption to challenges created by climate change is highly required. It is one of the major challenges for public authorities to reduce energy in existing public buildings without significant construction works. Therefore, public authority need to be equipped with simple but useful tools and methodologies (stable, long-term strategies) for proper energy management to increase EE and renewable energy usage in public buildings. The main project objective is to improving the governance of EE in existing public buildings and ultimately reducing energy consumption in different CE areas, especially those less advanced in low carbon approach. Due to transnational cooperation a meaningful attempt to solve the common problem of EE of public buildings will be made. Furthermore project will help raise public awareness, about the environmental, economic, and other benefits of energy saving issues which will result reducing know-how disparities. For this purpose OnePlace platform to transfer the knowledge to other regions of Europe will be developed. With the development and implementation of the 3D Energy Management System and pilot actions, the project will show an innovative approach towards energy auditing of buildings  and in a mid-term horizon will contribute to value added. The outcomes of the project can be replicated in other areas of the EU.
Advancing intuitive human-machine interaction with human-like social capabilities for education in schools

ANIMATAS will establish a leading European Training Network (ETN) devoted to the development of a new generation of creative and critical research leaders and innovators who have a skill-set tailored for the creation of social capabilities necessary for realising step changes in the development of intuitive human-machine interaction (HMI) in educational settings. This will be achieved through (1) a transnational network of universities and industrial partners that will supervise and deliver specialized training for early stage researchers (ESRs), and (2) the cross-fertilization of state-of-the-art methods from the domains of social robotics, embodied virtual characters, social and educational sciences in order to facilitate the development of skills necessary to design machines capable of engaging in intuitive sustained encounters with teachers and children. The ETN will ensure an integrative approach to the development of new capabilities with a view to their impact on whole system performance in terms of the complete HMI loop. This will be done by building industry–guided showcases that integrate the social capabilities developed by the ESRs. The participation of industrial partners will support the translation of new academic results to the market-place and a better transfer of knowledge between different sectors. The exposure of the non- academic sector to the ESRs has a great market potential that our industrial partners aim to capitalize upon in terms of recruiting young talents after the end of the project and adopting ANIMATAS’ advances in intuitive HMI for future product lines. This will greatly benefit the ESRs, which will be provided with new career perspectives in the social robotics and ed-tech industries. The ETN will strengthen Europe’s capacity in research and innovation by nurturing a new generation of highly skilled ESRs with an entrepreneurial mind-set and an understanding of intuitive HMI and potential products in these emerging markets.
Ethnogynaecological Assessment of Medicinal Plants in Pashtun’s Tribal Society

The present study was designed to document detailed ethnogynaecological knowledge of selected remote regions of Pashtun’s tribe in northwest Pakistan. Semistructured questionnaires were designed to collect ethnogynaecological and ethnographic data. Total of 51 medicinal plants belonging to 36 families were documented that were used by the women of studied regions for the treatment of 9 types of gynaecological complaints. Majority of the plants (19) were found used against menses followed by 11 plants each for gonorrhea and pregnancy. Bannu region has high number of gynaecological plants (22) followed by Karak (15). Women of the regions mostly used whole plants (33%) and leaves (31%) for various ethnomedicinal preparation of gynae. Fic results showed that all ailments in different areas scored high consensus ranges between 0.6 and 1.00. Majority of the female respondents (44%) were aged between 61 and 70 years, of which most were illiterate. Women in the remote regions of Pakistan have tremendous traditional knowledge in utilizing medicinal plants for their reproductive health. Plants with high Fic values should be cross-checked for their in vitro and in vivo validation. Young girls should be educated on the importance of ethnogynaecological practices to conserve this valuable knowledge.
The challenges of return migration in africa in the age of complex emergencies: comparing multilevel governance systems in ethiopia and nigeria

This project fills the research and policy gaps in the understudied phenomenon of return migration in Africa, against the backdrop of recent migration 'crisis' in Europe, the increasing securitization of the EU's external borders to curb irregular migration, and the complex emergencies faced by migrants transiting through Libya to Europe. It uses a multilevel governance (MLG) framework to explore the decision-making processes/politics of returning stranded migrants from Libya to their countries of origin in the context of interdependence between governmental actors and nongovernmental organizations at the local, national, regional, and global levels. The few previous studies on return migration in Africa have given relatively little attention to these critical linkages and their reciprocal constructions, in the integrated manner of the MLG approach. The project explores the effects of MLG dynamics on return migrants' reintegration, and the effects of institutional complexity on intergovernmental coordination and policy coherence. The empirical study focuses on Ethiopia and Nigeria, two key priority countries under the EU-IOM Joint Initiative for Migrant Protection and Reintegration, which have served as major countries of origin for migrants and which have witnessed the return of migrants from Libya. The project uses structured focused comparison and process tracing research design, and qualitative methods involving in-depth interviews with returnees and key informants, and document analysis. Consistent with the understanding of MLG as a complex interaction between multiple configurations of actors with divergent interests, ideas and power resources, this study will analyze the mechanisms through which multiple governance authorities interact to shape return migration policies/politics, how these multilevel policies/politics affect sustainable reintegration of returnee migrants, and the strategies used by these migrants to navigate complex MLG dynamics.
Responses of wintering geese to the designation of goose foraging areas in The Netherlands

The Netherlands is important for wintering migratory herbivorous geese, numbers of which have rapidly increased, leading to conflict with agriculture. In 2005/2006, a new goose management policy aimed to limit compensation payments to farmers by concentrating foraging geese in 80 000 ha of designated 'go' areas-where farmers received payment to accommodate them-and scaring geese from 'no go' areas elsewhere. Monthly national counts of four abundant goose species during 10 years prior to the new policy and in 8 years following implementation found that 57% of all goose days were spent within 'go' areas under the new management, the same as prior to implementation. Such lack of response suggests no predicted learning effects, perhaps because of (i) increases in abundance outside of 'go' areas, (ii) irregularly shaped boundaries and enclaves of 'no go' farmland within 'go' areas and/or (iii) insufficient differences in disturbance levels within and outside designated areas.
Assessing audiovisual saliency and visual-information content in the articulation of consonants and vowels on audiovisual temporal perception

Research has revealed different temporal integration windows between and within different speech-tokens. The limited speech-tokens tested to date has not allowed for the proper evaluation of whether such differences are task or stimulus driven? We conducted a series of experiments to investigate how the physical differences associated with speech articulation affect the temporal aspects of audiovisual speech perception. Videos of consonants and vowels uttered by three speakers were presented. Participants made temporal order judgments (TOJs) regarding which speech-stream had been presented first. The sensitivity of participants’ TOJs and the point of subjective simultaneity (PSS) were analyzed as a function of the place, manner of articulation, and voicing for consonants, and the height/backness of the tongue and lip-roundedness for vowels. The results demonstrated that for the case of place of articulation/roundedness, participants were more sensitive to the temporal order of highly-salient speech-signals with smaller visual-leads at the PSS. This was not the case when the manner of articulation/height was evaluated. These findings suggest that the visual-speech signal provides substantial cues to the auditory-signal that modulate the relative processing times required for the perception of the speech-stream. A subsequent experiment explored how the presentation of different sources of visual-information modulated such findings. Videos of three consonants were presented under natural and point-light (PL) viewing conditions revealing parts, or the whole, face. Preliminary analysis revealed no differences in TOJ accuracy under different viewing conditions. However, the PSS data revealed significant differences in viewing conditions depending on the speech token uttered (e.g., larger visual-leads for PL-lip/teeth/tongue-only views).
EVALUACIÓN DEL USO DE LAS TIC Y SU IMPACTO EN LOS PROCESOS COMERCIALES DE LA INDUSTRIA MANUFACTURERA DE PRENDAS DE VESTIR DE LA CIUDAD DE ATUNTAQUI AÑO 2014

The purpose of this research was to establish a more comprehensive picture of the use of Information Technology and Communication (ICT) in as important as manufacturing of clothing city city Atuntaqui sector. Through an exploratory-descriptive study, using tools such as surveys and interviews, was determined that the level of use of ICT in MSME Atuntaqui is mid-level, more so this result is lower by focusing on business processes, where an extremely reduced use of these technologies as a means to generate new business models and generate competitive advantages percentage was evident. Additionally it was determined the main causes of why they have not been adopted ICT to business management including lack of financial resources, lack of trained personnel in ICT issues, and ignorance of the benefits offered to companies. In the study an objective view of the current state of the use of ICT in manufacturing of Atuntaqui are presented for both public sector authorities and industry representatives, take steps in the process of business growth.
METHOD FOR MAKING A CHEMICAL DEVICE ELEMENT COMPRISING A METAL SUPPORTING PART AND AN ANTI-CORROSIVE METAL COATING

The invention concerns a method for making assembly parts (101, 192, 111, 112) for manufacturing a chemical device element (100) comprising fixing an anticorrosive coating (31, 32) on an untreated assembly part (21, 22), by an operation including a brazing process under controlled atmosphere and, optionally forming the coated part (101, 102) by plastic deformation. The brazing temperature is preferably lower than about 750 DEG C, and more preferably ranging between 600 DEG C and 720 DEG C. The inventive method enables an anticorrosive coating having a thickness less than 1 mm to be firmly fixed on a steel plate.
Pengaruh Corporate Governance dan Profitabilitas Terhadap Penghindaran Pajak Pada Perusahaan Manufaktur Yang Terdaftar Pada BEI Periode 2011-2015

This study aims to determine the effect of corporate goverenance, profitabilitas against tax evasion. The population of this study is a manufacturing company listed on the Indonesia Stock Exchange in 2011-2015. Sample selection in this research using purposive sampling technique. The number of samples used in this study were 570 samples. The type of data used in this study is secondary data derived from the website Indonesia Directory Exchange (IDX). The analytical technique used in this study using multiple partial least square. The result of multiple linear regression analysis shows that corporate governance, profitabilitas have a effect on tax avoidance.
Key words : company size, company ownership structure, leverage, profitability, corporate governance, tax avoidance.