SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Open participatory engagement in collective awareness for redesign of care services

OpenCare prototypes a community-driven model of addressing social and health care, and explore its implications at scale. It draws on three elements: advances in collective intelligence research, to lend coherence and summarize large-scale online debates; advances in digital fabrication and cheap-and-open hardware technology; and the rise of a global hacker community, willing and able to look for solutions to care problems. We explore the potential of this approach to deliver innovative, human-centric care solutions that combine the low bureaucratization and low overhead of communities with the scientific knowledge and technical skills associated to state- and market-provided professional care.

OpenCare orchestrates an open-to-all, community-driven process for addressing care issues, recruiting its participants from existing communities innovating at the edge of society (among others, hackers, artists, activists, designers). This entails the complete design cycle of sensemaking => selection of a problem-solution pair => prototype => testing => evaluation at scale; each step of the cycle will be radically open, with the debate happening online and the fabrication happening in hackerspaces and fully documented. We release open data and deploy onto them state-of-the-art analytical tools for collective intelligence: online ethnography and social network analysis. We integrate these two approaches into a semantic edges analysis approach.

We expect two main types of impact. The first: contributing to a better understanding of how to deploy the collective intelligence of smart communities onto sustainability problems. The second: contributing to the debate on reforming care provision in Europe by exploring how community-driven care services might integrate in the existing European care policy landscape.

OpenCare is delivered by a diverse consortium drawn from Europe’s best universities and the grassroots hacker community.
Teaming to upgrade to excellence in environmental biology, ecosystem research and agrobiodiversity

The BIOPOLIS proposal of ICETA (Institute for Research in Agroenvironmental Sciences and Technologies), an institution from a Widening Member Country (Portugal), addresses the upgrade of its research unit CIBIO (Research Centre in Biodiversity and Genetic Resources) to a Centre of Excellence (CoE) for R&D&I, through a teaming with a leading scientific institution, the University of Montpellier (France), and with the participation of a business partner, the Porto Business School (PBS; Portugal). The proposal results from a successful application to the call H2020-WIDESPREAD-2016-2017, under the topic WIDESPREAD-04-2017. Rooted on an ambitious Business Plan, the project envisions to establish BIOPOLIS as one of the best international Centres of Excellence in Environmental Biology, Ecosystem Research and AgroBiodiversity, with the capacity for spreading excellence towards innovation in the areas of Environment, Biodiversity and Agriculture, and thereby contributing to socioeconomic development at the regional and national levels. The CoE will advance biological understanding from genes to ecosystems, and to use this knowledge to address pressing societal challenges through the development of world-leading research, the establishment of long-term strategic partnerships, the engagement of stakeholders, and the transfer and exploitation of research outputs. This will be achieved by attracting talented researchers, providing excellent conditions for research, training, internationalisation and networking, aligning research with societal challenges and smart specialisation strategies, engaging in ambitious advanced training programmes, developing strong communication, dissemination and exploitation activities, and setting a strong affiliates programme and other mechanisms to promote the translation of research and innovation into applications and business opportunities. BIOPOLIS will thus upgrade excellence in a widening country and promote sustainable economic development.
Michael Goheen’s “A Light to the Nations”

Michael Goheen currently serves as Professor of Missiology as Calvin Theological Seminary in Grand Rapids, Michigan. He has authored and co-authored several books on missiology, theology, ecclesiology, and worldview. A Light to the Nations is an attempt to integrate a theology of mission with a biblical ecclesiology. In this book, Goheen skillfully constructs a missional ecclesiology. However, this work differs from others in the same category based on his “sustained biblical-theological and exegetical work (ix).” With the storyline of Scripture as his guide, Goheen traces the missional thrust inherit in God’s people from the formation of Israel to contemporary local churches. His targeted audience is theological students and church leaders, but the book is both accessible and applicable to lay leaders in the church.
Dante e il prosimetro. Dalla 'Vita nova' al 'Convivio'

This volume presents the Proceedings of the 19th International Conference on Italian Literature in the "Gennaro Barbarisi" series, which took place over 15-23 October 2020. To mark the septcentenary of Dante Alighieri's death (1321-2021), the Conference was dedicated to the theme of Dante and the Prosimetrum. From the 'Vita nova' to the 'Convivio'. Due to the pandemic, the conference could not be held in the usual setting of Palazzo Feltrinelli in Gargnano del Garda, but was organized remotely on four individual days, in collaboration between the Department of Literary Studies, Philology and Linguistics of the University of Milan and the Department of Italian of the University of Fribourg, Switzerland.&#x0D; Questo volume raccoglie gli Atti del XIX Convegno internazionale di Letteratura italiana "Gennaro Barbarisi", svoltosi a distanza, a causa della pandemia, tra il 15 e il 23 ottobre del 2020 e dedicato, nella ricorrenza del settecentesimo anniversario della morte di Dante Alighieri (1321-2021), a Dante e il prosimetro. Dalla 'Vita nova' al 'Convivio'. Le quattro giornate di studio, che non si sono potute tenere nella consueta cornice di Palazzo Feltrinelli a Gargnano del Garda, sono state organizzate in collaborazione fra le due sedi del Dipartimento di Studi letterari, filologici e linguistici dell'Università degli Studi di Milano e del Dipartimento di Italiano dell'Università di Friburgo in Svizzera.
The γδ cells as marker of non-seroconverted cattle naturally infected with Mycobacterium avium subspecies paratuberculosis

Early diagnosis of MAP infection is a pressing need to enable efficient intervention with the spread of MAP infection in herds. Hence, study of lymphocyte subsets and their expressed adhesion molecules could contribute in defining a distinct diagnostic marker (or markers) at the subclinical period of the infection that could in turn facilitate the development of effective diagnostic approach. In accordance with this objective, milk and blood samples were collected from two groups of cattle naturally infected with MAP and their corresponding negative controls. Group (C) comprised 3-4 year-old ELISA negative/PCR positive-cattle that were considered as subclinical seronegative low shedder group (early stage). Group (A) included 6-8 year-old ELISA positive-cattle, which were considered as a clinical seropositive group (late stage). Flow cytometry of B cells, CD8(+), CD4(+) and gammadelta cells and the adhesion molecules CD44(+), CD62L, LFA-1 and LPAM-1 indicated increase in CD4(+) and B cells levels, with higher levels in blood than milk of group A, and significant expression of CD44(+) in blood and milk and LPAM-1 in blood only. The CD8(+) cells count in milk was higher than blood in the late stage. The peculiar feature of the early stage (group C) was the high level of gammadelta cells in the blood and milk, with tendency to express high level of CD62L. Compelling evidence could support the assumption that the dominant gammadelta cells at early stage of MAP infection could be of CD8CD2(-)WC+1(+) phenotype. gammadelta cells appear as promising markers in defining early changes of MAP infection due to their important role in priming innate and cell mediated immunity. Possible utilization of these peculiar changes in the gammadelta cells level in the early diagnosis of MAP infection should be the subject of further research.
Design of a monolithic matter-wave interferometer for gravity sensing and navigation

Interferometry is a universal, precision metrology tool. Matter wave interferometers have been developed over the last decades and are now used as gravimeters for prospecting and geoscience and in fundamental studies, i.e. of quantum coherence, gravitational constant measurements and dielectric response. Research is ongoing  for use as accelerometers for long distance, under-water navigation and for dark matter and gravitational field exploration in space. Monolithic interferometers, where diffraction slabs are cut into a single crystal, are particularly attractive in the latter contexts due to their unsurpassed thermal and mechanical stability. However, up till now no monolithic interferometers for atoms have been realised, because atoms cannot penetrate the diffraction slabs. This project presents a completely new idea: A reflective monolithic atom interferometer with reflective slabs cut into a silicon monolith. Two configurations are considered: i) Surface Diffraction: Scattering at the intermolecular potential of Si(111)-H(1x1) (can be used with light atom beams only) and ii) Quantum diffraction: scattering at the dispersion potential from a blazed grating (can be used with all atom beams). The aim of this project is to provide a theoretical model of the new interferometer based on realistic experimental conditions and use the model to evaluate the new instrument for dark matter/gravitational waves exploration, prospecting and navigation applications. The project connects interdisciplinary expertise - the applicant Dr. Fiedler, expert on the theoretical description of matter-wave optical devices, Prof. Holst, expert on matter wave instrumentation, machine learning expert, Ass. Prof. Parviainen and theoretical particle physicist Prof. Kersten. The applicant will learn machine learning techniques, while improving several transferable skills, including scientific and grant application writing, open data and research management and science communication skills.
Travelling Waves in Hybrid Chemotaxis Models

Hybrid models of chemotaxis combine agent-based models of cells with partial differential equation models of extracellular chemical signals. In this paper, travelling wave properties of hybrid models of bacterial chemotaxis are investigated. Bacteria are modelled using an agent-based (individual-based) approach with internal dynamics describing signal transduction. In addition to the chemotactic behaviour of the bacteria, the individual-based model also includes cell proliferation and death. Cells consume the extracellular nutrient field (chemoattractant), which is modelled using a partial differential equation. Mesoscopic and macroscopic equations representing the behaviour of the hybrid model are derived and the existence of travelling wave solutions for these models is established. It is shown that cell proliferation is necessary for the existence of non-transient (stationary) travelling waves in hybrid models. Additionally, a numerical comparison between the wave speeds of the continuum models and the hybrid models shows good agreement in the case of weak chemotaxis and qualitative agreement for the strong chemotaxis case. In the case of slow cell adaptation, we detect oscillating behaviour of the wave, which cannot be explained by mean-field approximations.
Continuous wavelet transforms of spectral decomposition analyses for fluvial reservoir characterization of Miano Gas Field, Indus Platform, Pakistan

Fluvial depositional systems constitute diverse host for the hydrocarbons all over the globe. Nevertheless, predicting the hydrocarbon sands within these assorted sand systems is a challenge for the prospect generation. We apply the continuous wavelet transform of spectral decomposition technique to a 3D seismic data of the Miano Gas Field in the Indus Platform, Pakistan. Full spectrum seismic attributes like the amplitude and root mean square (RMS) detect the reservoir sands down to a restricted reservoir compartment. Nonetheless, the continuous wavelet transforms can be advantageous in imaging and enactment of these clastic reservoirs within the whole reservoir zone. Rock physics reveal high-quality reservoir with an average porosity ∼25% together with the discrimination of lithology/fluids, signifying the bright chances for ascertaining the potential stratigraphic reservoirs.
Effects of stacking order, layer number and external electric field on electronic structures of few-layer C<sub>2</sub>N-h2D

Recently, a new type of two-dimensional layered material, i.e. a nitrogenated holey two-dimensional structure C2N-h2D, has been synthesized using a simple wet-chemical reaction and used to fabricate a field-effect transistor device (Nat. Commun., 2015, 6, 6486). Here we have performed a first-principles study of the electronic properties of few-layer C2N-h2D with different stacking orders and layer numbers. Because of the interlayer coupling mainly in terms of the orbital interaction, band structure of this system, especially splitting of the bands and band gap, depends on its stacking order between the layers, and the band gap exhibits monotonically decreasing behavior as the layer number increases. All the few-layer C2N-h2D materials have characteristics of direct band gap, irrespective of the stacking order and layer number examined in our calculations. And bulk C2N-h2D has an indirect or direct band gap, depending on the stacking order. Besides, when we apply an out-of-plane electric field on few-layer C2N-h2D, its band gap will decrease as the electric field increases due to a giant Stark effect except for the monolayer case, and even a semiconductor-to-metal transition may occur for few-layer C2N-h2D with more layers under an appropriate electric field. Owing to their tunable band gaps in a wide range, the layered C2N-h2D materials will have tremendous opportunities to be applied in nanoscale electronic and optoelectronic devices.
DETECTING AND REMEDIATING DOWNHOLE EXCESSIVE PRESSURE CONDITION

A rotary subterranean drill capable of detecting an excessive downhole pressure condition and automatically remediating the causal condition of the detected excessive pressure condition. A pressure detector coupled to a drill string of the rotary subterranean drill can sense an excessive downhole pressure condition that exceeds a predetermined value. When an excessive downhole pressure condition is sensed at the pressure detector drag members are automatically disengaged from the borehole, thereby permitting rotation of the anchorable exterior portion within the borehole.
Study of Factors Affecting Taper Joint Failures in Modular Hip Implant Using Finite Element Modelling

The replacement of the natural hip with artificial components is a well established procedure in orthopaedic medicine to alleviate pain from the diseased joint. The total hip replacement (THR) consists of a femoral component or stem and an acetabular cup. These are made as either one piece or modular designs. Modular femoral components have become popular among surgeons because neck length and offset can be adjusted intraoperatively, providing increased versatility without any need for a large inventory. In addition, modular heads allow for mixed alloy systems such as the combination of a titanium alloy stem with a cobalt-chromium or ceramic head. Apart from the neck/head connection, there are femoral stem designs with extra areas of modularity. Examples of these prostheses are the S-ROM (Joint Medical Products, Stanford, Connecticut), the Infinity (Dow Corning Wright, Memphis, Tennessee), the RHMS (SmithNephew Richards, Memphis, Tennessee), and PROFEMUR Hip System (Wright Cremascoli Ortho SA, France). A major drawback for all modular orthopaedic devices is that each modular component interface becomes a potential site for corrosion, wear, fretting and fatigue of mating surfaces (Collier et al., 1992; Manley & Serekian 1994; Hallab & Jacobs, 2003; Goldberg & Gilbert, 2003; Hallab et al., 2004; Gilbert et al., 2009; Rodrigues et al., 2009). The products of these interface processes are believed to cause tissue reactions that lead to implant loosening and subsequent failure of the arthroplasty (Amstutz et al., 1992; Harris, 1994; Kraft et al., 2001; Goldberg et al., 2002). Thus, to make implant designs successful in clinical applications, these concerns need to be adequately addressed during the design stage of the prosthesis in conjunction with the implant strength and integrity of the implant-host bone system. Types of failures often encountered in modular hip implants are dissociation, corrosion, wear; fretting and fatigue of mating metal surfaces (Goldberg et al., 2002, Sporer et al., 2006; Rodrigues et al., 2009). There are varieties of design and material factors that may influence the failure of specific components. The most significant of these is fretting because is almost impossible to prevent and in many cases may lead to other form of failures. 8
Mechanism of interaction of novel uncharged, centrally active reactivators with OP-hAChE conjugates

A library of more than 200 novel uncharged oxime reactivators was used to select and refine lead reactivators of human acetylcholinesterase (hAChE) covalently conjugated with sarin, cyclosarin, VX, paraoxon and tabun. N-substituted 2-hydroxyiminoacetamido alkylamines were identified as best reactivators and reactivation kinetics of the lead oximes, RS41A and RS194B, were analyzed in detail. Compared to reference pyridinium reactivators, 2PAM and MMB4, molecular recognition of RS41A reflected in its Kox constant was compromised by an order of magnitude on average for different OP-hAChE conjugates, without significant differences in the first order maximal phosphorylation rate constant k(2). Systematic structural modifications of the RS41A lead resulted in several-fold improvement with reactivator, RS194B. Kinetic analysis indicated K(ox) reduction for RS194B as the main kinetic constant leading to efficient reactivation. Subtle structural modifications of RS194B were used to identify essential determinants for efficient reactivation. Computational molecular modeling of RS41A and RS194B interactions with VX inhibited hAChE, bound reversibly in Michaelis type complex and covalently in the pentacoordinate reaction intermediate suggests that the faster reactivation reaction is a consequence of a tighter RS194B interactions with hAChE peripheral site (PAS) residues, in particular with D74, resulting in lower interaction energies for formation of both the binding and reactivation states. Desirable in vitro reactivation properties of RS194B, when coupled with its in vivo pharmacokinetics and disposition in the body, reveal the potential of this oxime design as promising centrally and peripherally active antidotes for OP toxicity.
Obsessive-compulsive disorder: beyond segregated cortico-striatal pathways

Obsessive-compulsive disorder (OCD) affects approximately 2-3% of the population and is characterized by recurrent intrusive thoughts (obsessions) and repetitive behaviors or mental acts (compulsions), typically performed in response to obsessions or related anxiety. In the past few decades, the prevailing models of OCD pathophysiology have focused on cortico-striatal circuitry. More recent neuroimaging evidence, however, points to critical involvement of the lateral and medial orbitofrontal cortices, the dorsal anterior cingulate cortex and amygdalo-cortical circuitry, in addition to cortico-striatal circuitry, in the pathophysiology of the disorder. In this review, we elaborate proposed features of OCD pathophysiology beyond the classic parallel cortico-striatal pathways and argue that this evidence suggests that fear extinction, in addition to behavioral inhibition, is impaired in OCD.
The Snapshot of Mediterranean Hinterlands Richness

The overall objective of the project is to offer the strategy of protection and revitalisation of the hinterland areas which includes several aspects (cultural and natural resources) and connects the experiences from Croatia and Italy regarding the existence of the sustainable models in natural and cultural heritage management.
Activities in the project which will be implemented in the area of Split Dalmatia County and in the area of Italian regions are as follows:
Infrastructure works:
• Settlement of trekking, cycling and hiking paths along the Cetina River in order to improve the tourist offer of the area, settlement of the signalisation and settlement of small belvederes
• Settlement of the part of fortress Klis
• Settlement of trekking, cycling and hiking paths in the area of Italian regions involved in the project implementation (Basso Biferno and Sinello)
• Settlement of the so called interpretative centre in one of the historical fortresses in the area of Italian regions involved in the project implementation (Basso Biferno and Sinello)
Other activities:
• Unification of the tourist offer of the area (networking of the producers of the traditional gastronomy products, accommodation facilities etc.)
• Setting up of 6 project info points (Split, Vrlika, Šestanovac, Trilj, Dugi Rat, Zadvarje)
• Collection of data regarding the tourist offer of the area including the natural and cultural heritage, digitalisation of data and uploading the data at info-portals
• Organisation of seminars for the entrepreneurs in the tourist sector and other stakeholders in the tourist sector
Comparison of optical rhinometry to acoustic rhinometry using nasal provocation testing with Dermatophagoides farinae

OBJECTIVE: To evaluate optical rhinometry (ORM) as an objective evaluation of nasal patency using nasal provocation testing with Dermatophagoides farinae (Df) as compared with acoustic rhinometry. STUDY DESIGN: Prospective pilot. SETTING: Academic rhinologic practice. SUBJECTS AND METHODS: Five adult healthy controls and five adult subjects with allergic rhinitis (AR) underwent nasal provocation testing with increasing concentrations of Df while undergoing ORM. The minimum concentration of Df causing a positive reading was recorded. Nasal cross-sectional area was measured before and after testing using acoustic rhinometry. Nasal patency was assessed subjectively after each challenge with the visual analogue scale. RESULTS: The median amount of Df causing a positive response on ORM was less in AR patients as compared to healthy controls, at 5000 AU/mL and greater than 10,000 AU/mL, respectively. There was a statistically significant correlation between the change in optical density in ORM and subjective nasal congestion after increasing Df challenges (r = 0.63; P = 0.0007). Similarly, there was a statistically significant correlation between change in optical density by ORM and both minimum cross-sectional areas as measured by acoustic rhinometry (r = −0.60, P = 0.03; and r = −0.64, P = 0.02, respectively). CONCLUSION: This is the first study to show a correlation between optical rhinometry and acoustic rhinometry during nasal provocation testing with Df. In addition, the data support a correlation of optical rhinometry to subjective symptoms of nasal congestion. These preliminary data suggest that optical rhinometry is able to assess changes in nasal patency during challenges with Df. © 2010 American Academy of Otolaryngology-Head and Neck Surgery Foundation. All rights reserved.