SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Bisphenol A: invisible pollution

Bisphenol A (BPA) is a high volume chemical used in a wide variety of products, including plastic bottles and canned goods. Based on widespread human exposure and endocrine effects observed first in animal studies and now in humans, this chemical is being extensively studied. Most physicians have not had formal teaching regarding human risks from environmental exposures such as BPA. This article aims to provide: 1) a basis for learning about BPA as an environmental exposure and 2) practical advice for healthcare providers to share with concerned families.Human exposure to BPA is nearly universal. Animal studies have documented a variety of endocrine effects of this chemical and recent studies involving humans are resulting in growing concerns. These studies suggest that increased exposure to BPA is correlated with diseases such as heart disease and type 2 diabetes. Based on the metabolism of BPA and its endocrine effects, scientists hypothesize that the impact on children will be magnified. Further studies are needed to clarify this issue; funding has increased dramatically in recent years and scientists are hopeful that many of the currently unanswered questions will be addressed.The evidence for harmful health effects on humans from BPA exposure is incomplete, but is sufficient to suggest that limiting exposure is warranted. Further studies involving pregnant women and young children are needed to clarify the endocrine effects of BPA on this vulnerable population.
DOOR

The invention concerns a door that comprises a door frame (1), where the door frame (1) surrounds at least one surface or a space (2) that can be accessed through a slit in at least one side of the door, or in the end of the door, which slit makes it possible to carry out at least one of introduction and exchange of a decorative or informative sign (3) that is visible from at least one side of the door.
Consumo en pandemia: fakes news, saturación y autocontrol

Este trabajo tiene por objetivo indagar los cambios de hábitos en el consumo de medios en pandemia en jóvenes de clase media entre 18 a 24 años residentes en el Área Metropolitana de Buenos Aires (AMBA). Específicamente nos detendremos en algunos aspectos reiterados por ellxs: la circulación de noticias falsas y la desinformación, la saturación de información y las formas de autocontrol en el consumo de medios en contexto de pandemia por COVID-19. La metodología utilizada fue la entrevista focalizada realizadas por meet o zoom entre abril y junio de 2021.
Inventing a shared science diplomacy for europe

iThe European Commission calls for the development of effective science diplomacy (SD) for Europe. InsSciDE – Inventing a Shared Science Diplomacy for Europe – responds to this call with a hypothesis: Member States have a great capital of experience on which to draw. Domestic and transnational initiatives have long used science in global diplomatic engagements, in a diversity of ways and contexts. But this practice is fragmented, unrecognized, or lacking an overall model for leveraging and consolidation. InsSciDE will reveal, formalize and communicate this intangible capital, develop its conceptual bases and elaborate tools to help European SD emerge and blossom. From first questions to final tools and training, we lead this process from inside science diplomacy – hand in hand with its practitioners, potential practitioners and other stakeholders. Those who deploy, direct and benefit from SD are co-inventors, end-users and ambassadors for the project, accompanied by a research consortium associating academic excellence and high competence in stakeholder engagement. An ambitious communication program presents InsSciDEE to an international audience for feedback, widely disseminates the findings and intellectual products, and ensures their legacy.
InSScIDE devises a process through which new knowledge on past and present SD in Europe fuels the elaboration of shared policy and training tools. InsSciDE 's five interrelated goals are: Reveal and connect experience; map into theory and strategy frameworks; generate guidance; foster linkages; disseminate and sustain learning. Its high ambitions are made feasible by a project consortium of 14 respected research and training institutes from 11 countries spanning Europe, plus UNESCO; by explicit interest and support from European Academies of Science and from existing networks of diplomatic Attachés and Counselors for science, technology and innovation; and by the commitment of a high-level and diverse Advisory Board.
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Évolution en 2021 de l’enseignement de l’éducation thérapeutique du patient en formation initiale et place de la simulation dans cet enseignement : une enquête auprès de 92 instituts de formation en soins infirmiers français

Objectifs : Les objectifs de cette étude étaient de préciser l’évolution de l’enseignement de l’éducation thérapeutique des patients (ETP) depuis la dernière enquête de 2016 et de décrire la place de la simulation en santé dans cet enseignement dans les IFSI de France. Méthode : Une enquête nationale, par questionnaire, auprès des 331 IFSI de la France métropolitaine et Outre-mer a été réalisée. Le questionnaire de type descriptif a été conçu à partir d’une étude réalisée en 2016 portant sur le même objectif et complété au regard des objectifs de la présente étude. Trente-huit questions fermées et ouvertes abordaient l’enseignement de l’ETP et l’utilisation de la simulation dans cet enseignement. Résultats : Quatre-vingt-douze IFSI (28 %) ont participé à cette étude. L’enseignement en ETP a peu évolué au regard des résultats de 2016 mais les formateurs ont continué à se former. La pratique en stage reste insuffisante. Quarante et un IFSI (45 %) utilisaient la simulation dans les enseignements de l’ETP principalement des jeux de rôle et l’intervention des patients standardisés. Les séances de simulation permettaient selon les répondants de faire travailler les étudiants sur leur pratique réflexive et leur posture de soignant éducateur. Des freins au développement de la simulation étaient exprimés, en particulier le manque de temps. Discussion : Bien que l’enseignement de l’ETP ait peu évolué depuis 2016, l’étude montre que la simulation est de plus en plus utilisée pour former les étudiants en soins infirmiers. Si la simulation remplace en partie le manque de pratique en stage, elle doit être réfléchie pour permettre aux étudiants de travailler le transfert de leurs apprentissages à différentes éducations et au service sanitaire.
Relationship Between HMW Glutenin Subunit and Bread Making Quality of Wheat in Indian Cultivars

Varieties of bread wheat contain three to five high molecular weight (HMW) subunits of glutenin. The high molecular weight (HMW) subunits of glutenin are coded by genes at three genetically unlinked loci, Glu-1A, Glu-1B and Glu-1D, which occur on chromosomes 1A, 1B and 1D respectively. Glutenin is responsible for most of the viscoelastic properties of wheat flour doughs and is the main factor dictating the use of a wheat variety in bread making. The SDS-Sedimentation test determines the strength of the dough by recording the swelling of the flour. In present study, we had taken six popular bread cultivars viz; HD 2967, HD3059, PBW 373, C306, PBW 343 and NI 5439 and HMW proteins were extracted from single seed of each variety and different protein fractions were separated by SDS-PAGE. Glu-1-score, wet gluten content and the SDS-Sedimentation values in all the 6 genotypes under study were in perfect synchrony with highest Glu-1 scores and SDS-Sedimantaion value in HD2967 (10, 58) followed by HD3059(10, 55), C 306 (5, 42), NI 5439 (6, 57) PBW 343 (6, 36) and PBW 373 (6, 38). SDS sedimentation value has significant correlation with Glu-1 score, which indicates the bread making quality. We concluded that variation in bread making quality of the different varieties was due to varying Glu-1-score. 1B/1R translocation adversely affects milling quality, sedimentation value and end use quality.
Holistic benchmarking of big linked data

Linked Data has gained significant momentum over the last years. It is now used at industrial scale in many sectors in which an increasingly large amount of rapidly changing data needs to be processed. HOBBIT is an ambitious project that aims to push the development of Big Linked Data (BLD) processing solutions by providing a family of industry-relevant benchmarks for the BLD value chain through a generic evaluation platform. 
We aim to make open deterministic benchmarks available to test the performance of existing systems and push the development of innovative industry-relevant solutions. The underlying data will mimic real industrial data assembled during the course of the project. At the beginning of the project, HOBBIT will work on roughly 1PB of real industry-relevant data from 4 different domains. The data will be extended through collaborations during the project. 
To push the use of the benchmarks, we will organize or join challenges that aim to measure the performance of technologies for the different steps of the BLD lifecycle. In contrast to existing benchmarks, we will provide modular and easily extensible benchmarks for all industry-relevant BLD processing steps that allow to assess whole suites of software that cover more than one step.
The infrastructure necessary to run the evaluation campaigns will be made available. Our architecture will rely on web interfaces and cloud infrastructures to ensure scalability. The open HOBBIT platform will make human- and machine-readable, public periodic reports available. As exit strategy, the project will create an association after the second project year that will be sustained by the means of subscriptions from industry and academia and associated with existing benchmarking associations. The clear portfolio of added value for the members will be defined in the early project stages and disseminated throughout the evaluation campaigns.
Simulating cardiac electrophysiology using anisotropic mesh adaptivity

Abstract The simulation of cardiac electrophysiology requires small time steps and a fine mesh in order to resolve very sharp, but highly localized, wavefronts. The use of very high resolution meshes containing large numbers of nodes results in a high computational cost, both in terms of CPU hours and memory footprint. In this paper an anisotropic mesh adaptivity technique is implemented in the Chaste physiological simulation library in order to reduce the mesh resolution away from the depolarization front. Adapting the mesh results in a reduction in the number of degrees of freedom of the system to be solved by an order of magnitude during propagation and 2–3 orders of magnitude in the subsequent plateau phase. As a result, a computational speedup by a factor of between 5 and 12 has been obtained with no loss of accuracy, both in a slab-like geometry and for a realistic heart mesh with a spatial resolution of 0.125 mm.
“There’s a Pain App for That”

There are a growing number of pain self-management applications (apps) available for users to download on personal smartphones. The purpose of this study was to critically appraise the content and self-management functionality of currently available pain apps.An electronic search was conducted between May and June 2014 of the official stores for the 4 major operating systems. Two authors independently identified patient-focused apps with a stated goal of pain management. Discrepancies regarding selection were resolved through discussion with a third party. Metadata from all included apps were abstracted into a standard form. The content and functionality of each app as it pertained to pain self-management was rated.A total of 279 apps met the inclusion criteria. Pain self-care skill support was the most common self-management function (77.4%). Apps also purported providing patients with the ability to engage in pain education (45.9%), self-monitoring (19%), social support (3.6%), and goal-setting (0.72%). No apps were comprehensive in terms of pain self-management, with the majority of apps including only a single self-management function (58.5%). In addition, only 8.2% of apps included a health care professional in their development, not a single app provided a theoretical rationale, and only 1 app underwent scientific evaluation.Currently available pain self-management apps for patients are simplistic, lack the involvement of health care professionals in their development, and have not been rigorously tested for effectiveness on pain-related health outcomes. There is a need to develop and test theoretically and evidence-based apps to better support patients with accessible pain care self-management.
Diagnostic reference levels for paediatric computed tomography

Objectives: To establish local diagnostic reference levels (LDRLs) for emergency paediatric head computed tomography (CT) scans performed at a South African (SA) tertiary-level hospital and to compare these with published data.Materials and methods: A retrospective analysis was conducted of volume-based CT dose index (CTDIvol) and dose length product (DLP) data from uncontrasted paediatric head CT scans performed in the Trauma and Emergency Unit of a tertiary-level SA hospital from January to June 2013. A random sample of 30 patients in each of 3 age groups (0–2, &gt;2–5 and &gt;5–10 years) was used. LDRL values were compared with several national DRLs from Europe and Australia. Results: Mean CTDIvol and DLP values were: 30 mGy and 488 mGy.cm for the 0–2 years age group; 31 mGy and 508 mGy.cm for the &gt;2–5 years group, and 32 mGy and 563 mGy.cm for the &gt;5–10 years group, respectively. The mean DLP for 0–2 year-olds was the only parameter outside the range of corresponding published reference data. Stratification into narrower age groupings showed an increase in DLP values with age. Conclusion: An institutional review of the head CT scanning technique for emergency studies performed on children less than 2 years of age is recommended. The current study highlights the role of LDRLs in establishing institutional dosimetry baselines, in refining local imaging practice, and in enhancing patient safety. Standard age stratification for DRL and LDRL reporting is recommended.
Developing a cure for retinitis pigmentosa due to usher syndrome

The GeneVision proof-of-concept project spins from a major discovery made by the principle investigator (PI) within the RetGeneTx ERC project demonstrating that dual AAV vectors expand AAV DNA transfer capacity in the retina thus allowing delivery of genes whose size cannot be packaged in single AAVs. Thus, dual AAV vectors allow gene therapy of those inherited blinding conditions, like Usher syndrome type Ib (USHIB), Stargardt disease or other forms of retinitis pigmentosa, due to mutations in large genes from which the AAV platform, the best to date for in vivo gene therapy, was so far precluded. 
GeneVision’s objective is to bring this initial proof-of-concept in animal models up to commercialization for one retinal application, USHIB, which is particularly severe and early onset. By exploiting both the Orphan Drug Designation obtained from the European Medicina Agency and two patent applications based on data generated by the PI during its consolidator ERC grant, GeneVision will support the early phase clinical development to bring this very innovative gene therapy platform for retinitis pigmentosa up to commercialization. To do so the project plans  to validate the business plan already outlined in the proposal, and seek seed funding to create a start-up company which would engage in all activities required to develop a phase I/II trial. If this is successful, the longer plan is to obtain two additional rounds of funding to support a pivotal trial to complete the data required to obtain market authorization and start commercialization. . The success of this project will lay the foundations for the development of therapies for other retinal and non-retinal diseases using dual AAV vectors.
Preparing Tryumf for the implementation of a new business model related to the internationalisation of the enterprise.

Work NAD MBI Time of work: in the period April/May 2021, corrections were made to the IBI in October 2021, which take into account the comments of the KOP and the person examining the protest. How the work is carried out: The external advisor (OEG) fully implemented the new MBI, based on consultations with Tryumf. The work was carried out using a survey of self-diagnosis, desk research, brainstorming, in-depth interviews, workshops, etc. As part of the work, teleconferences, telephone and e-mail conversations took place. Products FOR INTERNATIONATION Product group — cast medals. UAE, Morocco, Egypt, Tunisia Tasks • Development of MBI • Advisory services 12 studies — market research x 4 and selection and selection of contractors x 8 • Development of a promotional campaign • Design and printing of catalogues • Workshops • Translations • Development of an advertising film • Participation in business missions — 4 pcs. • Purchase of new fixed assets — 1 pc.
Malleable surgical retractor for complete exposure of mitral valve

Heart valves play a key role in the way blood flow, opening and closing with each heartbeat. Almost all interventions in cardiac surgery are performed to repair or replace the mitral, aortic or tricuspid valve. In specific case of mitral valve surgery, good exposure of mitral valve and its ring is essential for the surgeon
Conventional mitral valve surgery is performed opening the sternum (20-25cm) with a retractor and then surgical operation is carried out.  The use of minimally invasive (MIS) surgery allows decrease of recovery time, decrease of surgical trauma, reduction of pain improving patient satisfaction and reducing hospital resource utilization. All this advantages, make that nowadays half of mitral surgery operations are made in developed countries following MIS techniques. Main drawback of MIS surgery is that operation areas exposure is limited which makes surgeons work harder than doing it in open surgery. Better exposure translates into better surgical results, optimal stability of the surgery and optimal long-time clinical results. In Minimall invasive mitral surgery, only an anterior traction retractor is used but the exposure that allows to the surgeon is limited. 
Due to aging of population and development of emerging countries, mitral valve surgical procedures are growing market worldwide expecting to double its actual size for 2030.
In this scenario, ANSABERE in collaboration with Dr. Anas Sarraj (surgeon of Hospital La Princesa in Madrid and associate professor of Autonomous University of Madrid) has developed an innovative device for both mitral conventional and MIS surgery, called SALAS, that provide better and complete exposition of the mitral valve and its ring from inside the left atrium. The instrument allows to surgeon to adjust and adapt the working area due  to the use of the lateral flap and the malleability of the arms of the invention.
Smart freight transport and logistics research methodologies

Freight transport and logistics are in a period of transformation where the increased availability of digital technologies is rapidly transforming market structures and logistics business models, and the legislative and policy frameworks are moving towards the minimization of the environmental impact of transport. The rapid structural, organisational, and behavioural changes of the sector make existing data, models, and tools lag behind current developments. In response, the STORM project aims to study transformation and structural changes in freight and logistics business structures from different perspectives, focusing on the future challenges and needs of the sector by developing new methods and tools to support digitalization, sustainability transition,   and future policy needs. STORM will create a unique platform for dialog with all relevant stakeholder groups to identify key elements for future horizons and directions for freight and logistics research, business and polices. The project will develop new generation, beyond current state-of-the-art transport data analytics, models and solutions through industry use cases and contribute to sector innovations and competitiveness. STORM output will be a toolbox bringing together tools and methods centring on Big Data, data fusion, and agent-based modelling applied to electrified freight transport concepts and new collaborative, digitised logistics systems. It responds to the emerging needs of transport researchers, planners, and policy makers and it will generate knowledge for the implementation of innovative transport policies. STORM will provide advanced methods and tools to enable new opportunities and business models for the sector through targeted information and knowledge sharing with structured support and collaboration in research, policy analysis, and transport planning, to fulfil the ultimate goal of facilitating the sustainable transformation for the business and future public policies.
DIAGNOSTIC PROBE SUITABLE FOR ASCORBIC ACID DETECTION

A diagnostic probe or chemical sensor includes a solid substrate or support material carrying copper-gold alloy nanoparticles. The probe or sensor is particularly suitable for sensing the presence of ascorbic acid and a method of detecting ascorbic acid in a sample is thus also disclosed. The invention extends to a method of manufacturing a diagnostic probe or chemical sensor which includes forming a liquid admixture that includes copper-gold alloy nanoparticles and a substrate or support material, and solidifying the liquid, nanoparticle-containing admixture into a solid body.