SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
“Planificación y Gestión del Turismo en el Cantón Montalvo, Provincia de Los Ríos”

The present investigative work focuses on the analysis of the influence of tourism planning and management, in the Montalvo Canton, Los Rios Province, for this reason, a descriptive and explanatory research has been applied, it presents a transversal non-experimental design of the type descriptive with the application of this design we sought to determine the influence between the variables the research used techniques and instruments as direct observation and the survey for the collection of data for research on general information, processes, organization, objectives, competitive advantage, production and resources, aimed at workers of the Tourism Unit and entrepreneurs in the tourism sector; Through the surveys, data was obtained that helped to understand the current situation of planning and management. As a result of this process, the hypothesis test was carried out, which led to the conclusion that planning has a significant influence on tourism management; finally, conclusions and recommendations and a proposal for an improvement plan in tourism planning were made to optimize tourism management. However, with the present study it is evident the need to continue with future investigations that allow the study and analysis of each one of the indicators of the Planning with those of the Management.
SADLE. Acting and Directing Systems for Space Launchers

The Sadle project promotes the I&D of space technology to guide and control the trajectory of the first Portuguese space launcher for small satellites, valuing the capabilities offered by the future national Space Port and inserted in the strategy of Portugal Space.
Disrupting the food safety chain. the decontamination unit that removes more than 99% of pathogenic bacteria during poultry meat slaughtering and processing

Hygiene procedures to avoid the growth of spoilage and pathogenic bacteria within the food supply chain are only preventive since no better available decontamination methods exist, and their inefficiency is reflected by the high prevalence of foodborne outbreaks reported. In 2016, 356,6124 human cases of zoonoses were reported in the EU, with Salmonella and Campylobacter jejuni being responsible for most of them.
DECON SFS is a Norwegian company led by Vidar Julien (communications and crisis management director at Nutreco NV for 10 years), created to develop and commercialize food decontamination technologies eliminating bacteria from poultry meat. The result of 8 years and € 4.5M is Deconizer (TRL6-7), a decontamination unit based on hydro thermal bacteriolysis (HTB) technology, which uses superheated steam in combination with a large electromagnetic field which charges the steam particles directing them towards the meat surface eliminating 99% of bacteria. Deconizer has been tested and validated in laboratory (at the Norwegian Food Research Institute, Nofima) and real operation conditions in the Spanish companies SADA and PUJANTE, confirming decontamination rates over 99%. Deconizer´s uniqueness relies in the reduction of carcasses cross-contamination, while having no impact on visual appearance, taste, smell or colour and extending products’ shelf life. Meat is still fresh, opposed to some preventive decontaminating methods relying on freezing and hot water.
Given there are not big competitors on the market, we expect to sell at least 56 Deconizer units across slaughterhouse poultry processing plants in the first 3 years of commercialization to reach € 16.1 M of revenues (ROI of 4.2), while creating 10 direct new jobs. The IP generated, will also allow DECON SFS to expand the application portfolio, since HTB can be applied to other types of highly consumed meat (e.g. pork, beef and sheep).
TOURISM WATER MANAGEMENT FOR SUSTAINABLE ADRION COASTAL AREAS

CHALLENGES AND INVERVENTION OBJECTIVES: TOUREST will support the development and proliferation of sustainable tourism policies & practices to increase water efficiency in ADRION coastal areas, seeking to: a) minimise the negative impacts of tourism activities on natural heritage, and b) protect increasingly scarce water resources. These focal interventions points will directly contribute to the implementation of the 4th EUSAIR pillar._x000D_
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ΜΑΙΝ TARGET GROUPS: Territorial public authorities & bodies responsible for policies on water efficiency, environment, and tourism SMEs & enterprises in the tourism sector. Key stakeholders, such as water infrastructure providers, business support organisations, and environmental agencies._x000D_
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OVERALL APPROACH AND MAIN OUTPUTS: TOUREST partners will employ a comprehensive and integrated studying, testing, and transferability approach, rooted in transnational cooperation, involving all aforementioned target groups and stakeholders. Its main outputs are:_x000D_
- A joint ADRION area strategy and resources for public authorities to monitor & assess sustainable tourism water management  (O.T1.1)._x000D_
- Demonstration of water use monitoring and assessment impact on increasing the sustainability level of the tourism sector (O.T2.1)._x000D_
- Action plans (x6) for public authorities and tourism stakeholders of the partners’ areas (O.T3.1)._x000D_
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To this end, TOUREST will produce the following main deliverables:_x000D_
- Studies and policy recommendations for public authorities to support the integration of sustainable tourism water management measures, and for tourism enterprises to adopt best management practices in day to day operations (supporting O.T1.1, O.T3.1)._x000D_
- Water sustainability indicators & evaluation criteria to measure tourism sector performance on water efficiency (supporting O.T1.1)._x000D_
- An innovative digital tool for SMEs & enterprises to monitor, compare, and self-assess water efficiency performance & efforts, and for public authorities to assess the overall territorial situation (supporting OT2.1)._x000D_
- Capacity building resources and policy workshops on sustainable tourism water management (supporting O.T3.1).
Which is false: Oxaliplatin or fluoropyrimidine? An analysis of patients with KRAS wild-type metastatic colorectal cancer treated with first-line epidermal growth factor receptor monoclonal antibody

This meta-analysis was performed to determine whether the addition of monoclonal antibodies (mAbs) of epidermal growth factor receptor (EGFR) to oxaliplatin-based chemotherapy treatment improves efficacy in KRAS wild-type metastatic colorectal cancer (mCRC), and whether infusional 5-fluorouracil (5-FU) and oxaliplatin is a preferred combination for EGFR mAbs. Oxaliplatin (including treatment), EGFR mAbs, first-line treatment, KRAS wild-type, and mCRC were used as key words. The PRIME, OPUS, COIN, and NORDIC VII trials were identified by two independent authors. Time-to-event outcomes of overall survival (OS) and progression-free survival (PFS) were analyzed using HRs (hazard ratios) with fixed effect, and response rate (RR) using odd ratios (OR) with fixed effect. A total of 1767 patients who were KRAS wild-type were included in this meta-analysis, with 866 patients in the mAbs and chemotherapy combination group and 901 patients in the chemotherapy alone group. The addition of mAbs to oxaliplatin-based chemotherapy in patients with KRAS wild-type mCRC as first-line treatment resulted in significant improvements in PFS (HR = 0.88; 95% confidence interval (CI), 0.79-0.99; P = 0.03) and response rate (RR) (OR = 1.38; 95% CI, 1.14-1.66; P = 0.009) compared with chemotherapy alone, but the difference in OS was not significant (HR = 0.96; 95% CI, 0.85-1.08; P = 0.48). However, the differences in OS and PFS were not significant when mAbs were added to bolus 5-FU or capecitabine-based regimens compared with chemotherapy alone, whereas PFS improved with an infusional 5-FU and oxaliplatin combination (P = 0.06; PFS, HR = 0.76; 95% CI, 0.65-0.86; P = 0.0002), and even OS was marginally significant, which was consistent with the subgroup analysis of cetuximab and panitumumab. EGFR mAbs combined with oxaliplatin and an infusional 5-FU regimen was associated with significantly improved RR, PFS and OS as first-line treatment in KRAS wild-type mCRC.
Validity of the Hospital Anxiety and Depression Scale and the Beck Depression Inventory for use in end-stage renal disease patients

To validate the Hospital Anxiety and Depression Scale (HADS) and the Beck Depression Inventory (BDI) for use in patients with end-stage renal disease (ESRD) and to compare the outcome of both screening measures with each other.Cross-sectional and between-subjects design. The independent variable was the diagnosis depression by the Mini International Neuropsychiatric Interview (MINI). The dependent variables were the HADS and BDI total score.All 130 patients with ESRD who were treated with haemodialysis (HD) or peritoneal dialyses in the Sint Lucas Andreas Hospital in Amsterdam were eligible for this study and were asked to fill out both HADS and BDI. The outcomes of both rating scales were compared with the diagnosis major depressive episode based on the MINI, which was seen as the gold standard. Receiver operating characteristic curves were used to choose optimal cut-off values.Of 62 enrolled subjects, 21 (34%) were diagnosed with a depressive disorder. Optimal cut-off values were ≥12 (HADS) and ≥13 (BDI). Sensitivity was 81.0% (HADS) and 75.0% (BDI). Specificity was 90.2% for both.Both HADS and BDI are valid screening instruments for the diagnosis depression in ESRD patients but there is no statistical difference found between both rating scales.
Subjective perception of sleepiness in a driving simulator is different from that in the Maintenance of Wakefulness Test

To test whether sleep-deprived, healthy subjects who do not always signal spontaneously perceived sleepiness (SPS) before falling asleep during the Maintenance of Wakefulness Test (MWT) would do so in a driving simulator.Twenty-four healthy subjects (20-26 years old) underwent a MWT for 40 min and a driving simulator test for 1 h, before and after one night of sleep deprivation. Standard electroencephalography, electrooculography, submental electromyography, and face videography were recorded simultaneously to score wakefulness and sleep. Subjects were instructed to signal SPS as soon as they subjectively felt sleepy and to try to stay awake for as long as possible in every test. They were rewarded for both "appropriate" perception of SPS and staying awake for as long as possible.After sleep deprivation, seven subjects (29%) did not signal SPS before falling asleep in the MWT, but all subjects signalled SPS before falling asleep in the driving simulator (p <0.004).The previous results of an "inaccurate" SPS in the MWT were confirmed, and a perfect SPS was shown in the driving simulator. It was hypothesised that SPS is more accurate for tasks involving continuous feedback of performance, such as driving, compared to the less active situation of the MWT. Spontaneously perceived sleepiness in the MWT cannot be used to judge sleepiness perception while driving. Further studies are needed to define the accuracy of SPS in working tasks or occupations with minimal or no performance feedback.
Multi-Scale mechanics of dynamic leukocyte adhesion

Leukocytes, white blood cells, patrol the vascular wall of our vessels in search of sites of inflammation. In the so-called leukocyte adhesion cascade, leukocytes flowing at high velocities (up to mm/s) impact the vessel wall, roll at µm/s, and finally migrate at nm/s to the site of inflammation. They are thus subjected to mechanical forces from sub-msec to several minutes. Complete understanding of the physical processes behind leukocyte adhesion requires an approach over multiple length and time scales, from single protein molecules to the whole cell. This is far from being established due, in part, to the lack of techniques covering the wide range of length and time scales involved. We have recently implemented high-speed atomic force microscopy (HS-AFM) to perform force spectroscopy measurements on biological samples with microsec time resolution. The novel acoustic force spectroscopy (AFS) traps hundreds of particles in parallel allowing hours-long measurements on single molecules.
MechaDynA proposes to develop and apply these two novel nanotools to allow force measurements on living cells with the goal of obtaining a complete, multi-scale picture of the physics behind the leukocyte adhesion cascade over the widest dynamic range (µs-min). This will require development of HS-AFM technology and coupling with advanced optical microscopy. We will probe the binding strength of single adhesion complexes, and membrane and cytoskeleton mechanics at physiologically relevant time scales not explored so far. Technologically, it will establish HS-AFM and AFS as force measurement tools for living cells covering the widest temporal range. This will open the door to unexplored physical phenomena in cell biology, biological physics and soft condensed matter. Biomedically, the expected outcomes will provide a mechanistic description of the physical phenomena in leukocyte immune response that may lead to better diagnosis and therapeutics.
DEVICE AND METHOD FOR TREATING BIOLOGICAL TISSUE WITH A LOW-PRESSURE PLASMA

The invention relates to a device for treating biological tissue (G) with a low-pressure plasma, said device comprising a) a transformer (1) for generating a high-frequency electromagnetic field, b) a probe (2) which can be electrically coupled to the transformer (1) and c) a control unit (3) for controlling the high-frequency electromagnetic field generated by the transformer (1). According to the invention, an information unit is associated with the probe (2), said unit being used to: e) measure and display both optically and/or acoustically the duration of the power output by the device to the tissue (G); and/or f) measure the current strength or the power output by the device to the tissue (G) and if a predefined limit value is exceeded, to interrupt the supply of energy to the device; and/or g) measure and display both optically and/or acoustically the distance of a treatment surface of the probe (2) from the tissue (G) to be treated.
Organic phases in cells: elucidating the physical nature of biological liquid droplets

Recently it has emerged that ‘membraneless organelles’ a commonly encountered body for compartmentalisation in Eukaryotic cells that include ‘nucleoli’ and ‘stress granules’, are phase separated liquid droplets suspended inside cells, formed from highly mobile disordered proteins. My research has focused on the prediction from physical theory, that the interior of liquid droplets should have very different chemical properties to the exterior dilute phase. By quantitatively analysing model biological liquid droplets formed by the Ddx4N1 protein, we discovered that their interior resembles an organic solvent (DMSO), can melt double stranded DNA, and selects which proteins can enter based on a simple sequence-based algorithm, akin to a chemical solubility rule.

The field of biological liquid droplets has largely focused on phenomenological observations. This proposal aims to step beyond this and test the central hypothesis that “intermolecular interactions drive biological liquid droplet formation to create regions of solvent tailored to promote specific chemical functions”. By studying a diverse range of biological liquid droplets, I seek to establish that physico-chemical properties explain both when liquid droplets mix and when they do not, explain which molecules are absorbed and which are not, use these features to predict new properties to design new functionalised sequences using rules based on their fundamental inter-molecular interactions, determine structures of the liquid droplets using NMR and cryo-electron tomography and investigate the effects of liquid droplets on chemical reactivity. 

This research has the potential to change our understanding of the mechanisms of biochemistry, and use principles from physical chemistry to explain why cells naturally create these regions of effectively organic solvent inside the cell as part of their life cycle.
Correct Enjoyment (and Awareness Raising) of Natura 2000 Locations

The CORALLO project supports the dissemination and use of the natural heritage through a diverse range of edutainment tools and minor and non-intrusive infrastructure interventions within Natura 2000 (N2K) sites. Through the project, state-of-the-art educational services and facilities will be developed in each of the target sites, including extensive use of virtual and extended reality including documentaries and short video clips. In addition, the iconic species and habitats encountered at each of N2K's target sites will be exhibited in different centers identified for intervention, thus capitalizing on the unique strengths and resources held by each site. The CORALLO project also provides mobile awareness tools, i.e. scientific campaigns for citizens, a boat of project information, smartphone apps and games and online tools, which will allow to reach a wide range of end users. CORALLO wants to achieve a greater degree of awareness of the biodiversity existing within N2K sites and the promotion of related ecosystem services. The project then carries out awareness-raising activities with as many end users as possible.
A reassessment ofMongolosaurus haplodonGilmore, 1933, a titanosaurian sauropod dinosaur from the Early Cretaceous of Inner Mongolia, People's Republic of China

The Early Cretaceous of China has yielded a diverse sauropod fauna, dominated by basal titanosauriforms. Known from a basicranium, teeth and the first three cervical vertebrae, Mongolosaurus haplodon is a poorly understood taxon whose evolutionary relationship to other sauropods has remained uncertain. Redescription of Mongolosaurus identifies key features that confirm its titanosaurian affinities and demonstrate its validity, based on several autapomorphies and a unique combination of characters. Diagnostic features include: a low neural spine which does not extend above the epipophyses; the dorsal edges of the posterior articular surfaces of anterior cervical vertebrae projecting more posteriorly than the ventral edges; and postaxial spinoprezygapophyseal laminae forming a dorsoventrally elongate X-shape in anterior view. Mongolosaurus is incorporated into three independent cladistic analyses; however, its precise phylogenetic position within Titanosauria remains unclear. This is partly a consequence of...
FERROUS OXIDE-BINDING PEPTIDES

The invention relates to a diagnostic means, comprising metal oxide particles, particularly ferrous oxide particles, which are coated with binding peptides. The binding peptides bind to the metal oxide particles at high affinity so that the peptide-coated metal oxide particles are suitable for medical applications, for example as a contrast medium for magnetic resonance tomography.
Facilitated third-party communications

In various embodiments, systems, methods, computer-readable media, and apparatuses for facilitation of communication between recipients and third-parties. A recipient, such, for example, a physician may request and then be facilitated in engaging in communication with a selected third party, such as a medical specialist. The third party may be selected based on the physician's request or on other information gained prior to or at the time of request, such as in response to a questionnaire. A context for the communication may be maintained during the communication and stored thereafter. During subsequent communication, the stored communication may be used to restore the previous context of the previous communication. Other embodiments may be described and claimed.
Active dielectric-on-si3n4 double layer platform

aSINdo will study the technical feasibility and commercialization strategy of on-chip optical gain building blocks based on rare-earth ion doped Al2O3 that can be integrated onto passive integrated photonic material platforms, in particular Si3N4, to realize on-chip amplifiers and lasers.  

The value proposition of this technology is to enable photonic integrated circuits to achieve sufficient output power to empower multiple emerging applications. Important advantages with respect to existing solutions are the manufacturability, cost reduction, power efficiency and building block approach, which will ease the adoption of this technology by design houses and system integrators.

In aSINdo we will increase the readiness level of the technology, we will define an IPR strategy and we will give the first
steps towards its commercialization by means of a market study and business plan. Dissemination activities will ensure
knowledge transfer to relevant parties, which may play a crucial role in defining the commercialization strategy.
PLASMA STERILIZER DEVICE FOR TREATING A GASEOUS MEDIUM CONTAINING MICRO-ORGANISM-, BACTERIA- OR VIRUS-TYPE CONTAMINANT PARTICLES

The invention relates to a plasma sterilizer device for treating a gaseous medium containing contaminant particles. The inventive device is characterized in that it comprises a central rod (51) which extends inside the treatment chamber (34) and a coil (52) which is mounted coaxially on the rod (51). The invention is suitable for use in the agri-food field.
Long-term groundwater variations in Northwest India from satellite gravity measurements

Abstract Satellite gravity data from the Gravity Recovery and Climate Experiment (GRACE) provides quantitative measures of terrestrial water storage (TWS) change at large spatial scales. Combining GRACE-observed TWS changes and model estimates of water storage changes in soil and snow at the surface offers a means for measuring groundwater storage change. In this study, we re-assess long-term groundwater storage variation in the Northwest India (NWI) region using an extended record of GRACE time-variable gravity measurements, and a fully unconstrained global forward modeling method. Our new assessments based on the GRACE release-5 (RL05) gravity solutions indicate that during the 10 year period January 2003 to December 2012, the NWI groundwater depletion remains pronounced, especially during the first 5 years (01/2003–12/2007). The newly estimated depletion rates are ~ 20.4 ± 7.1 Gigatonne (Gt)/yr averaged over the 10 year period, and 29.4 ± 8.4 Gt/yr during the first 5 years. The yearly groundwater storage changes in the NWI region are strongly correlated with yearly precipitation anomalies. In 2009, the driest season of the decade, the groundwater depletion reaches nearly 80 Gt, while in the two relatively wet seasons, 2008 and 2011, the groundwater storages even see net increases of about 24 and 35 Gt, respectively. The estimated mean groundwater depletion rates for the first 5 years are significantly higher than previous assessments. The larger depletion rates may reflect the benefits from improved data quality of GRACE RL05 gravity solutions, and improved data processing method, which can more effectively reduce leakage error in GRACE estimates. Our analysis indicates that the neighboring Punjab Province of Pakistan (especially Northern Punjab) apparently also experiences significant groundwater depletion during the same period, which has partly contributed to the new regional groundwater depletion estimates.
USING AUTHENTICATION TOKENS TO AUTHORIZE A FIREWALL TO OPEN A PINHOLE

Techniques are described for the use of a cryptographic token to authorize a firewall to open a pinhole which permits certain network traffic to traverse firewalls. An initiating endpoint requests a token from a call controller, which authorizes a pinhole though the firewall. In response, the call controller may generate a cryptographic authorization token (CAT) sent towards the destination endpoint. The call controller may generate the token based on an authorization ID associated with the call controller, a shared secret known to both the call controller and the firewall, and data specific to the media flow for which authorization is requested.