SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Pro-innovative services supporting the deployment of nanoperfum technology

Reference number of the aid programme: SA.42799(2015/X), intended for public aid: Article 28 of Commission Regulation No 651/2014The subject of the advisory services under the project will be NANOPERFUM technology. Technology in this case takes the form of the results of R & D works carried out by the Applicant – FINEA Sp. z o.o. NANOPERFUM technology includes: — Product technology (product innovation) – innovative formulation of product composition – the formulation will be based on water and fragrance composition (without allergens) and few (up to 10 %) non-ionic emulsifiers (safe, biocompatible with skin). — Manufacturing technology (processing innovation) – Application of low-energy AND high-energy two-stage METOD for the production of nanoemulsion. The project provides for the purchase of a number of services that will allow the efficient implementation of innovation into business practice: 1.Preparation for implementation: Identifying and mapping key business processes related to the implementation, modification and optimisation of innovation; Developing a marketing strategy; Prepare a detailed financial model for innovation being developed or implemented and analyse new technology and implementation in terms of their environmental impact. 2.Advice on intellectual property protection: Intellectual property management consultancy – research on the state of technology and purity of the patent solution and Development of intellectual property management strategy 3.Support for the implementation of innovations (pilot implementation): Assist in the development of the functional or technical documentation necessary for the implementation of innovations and Advice and assistance in developing and carrying out pilot innovation implementation. The services will be purchased in full from an accredited IOB: Netrix Group Sp. z o.o. The result of the project will be the implementation of 2 innovations (product and process) and ultimately the growth of the competitiveness of the micro-enterprise FINEA Sp. z o.o. in Po
Kidney transplantation - functional immunogenomics

Chronic renal failure affects ~10% of the world population and can gradually lead to end-stage renal disease (ESRD) requiring kidney transplantation. Despite the huge progress of immunosuppressive treatments, the host immune response against the graft still leads to rejection in many cases, with an average graft half-life of 10 years. Triggers leading to graft rejection are still largely unknown and need to be studied beyond the well-recognized impact of HLA mismatches.
I propose here to explore the effect of functional immunogenomic parameters beyond HLA mismatches (HLA alleles, HLA gene expression regulation, KIR...) on kidney transplantation outcomes (cellular and humoral rejections, tolerance). To achieve this present-day clinical challenge, I will combine innovative bioinformatics tools and modern genomics to perform cutting edge association studies: the Kidney Transplantation - Functional ImmunoGenomics (KiT-FIG) project. KiT-FIG ultimate goal is to provide new evidence to improve graft allocation and transplanted patients’ management.
Objective A is to develop innovative methods of HLA statistical inference to gain precision and generate additional functional immunogenomic parameters. Objective B is to apply these novel methods to investigate the impact of immunogenetics on immunological outcomes related to kidney transplantation. This objective will rely on genetic association studies to unlock the major scientific challenge of large and unexplained variability observed in renal graft survival.
KiT-FIG ambitions to develop new innovative bioinformatic and biostatistics tools to capture the complexity of HLA-related immune responses. These tools will be freely accessible to the community to expand immunogenetic studies of other diseases. The implementation of these tools in the context of kidney transplantation outcomes will increase the understanding of underlying immunological mechanisms and will contribute to improve graft survival and patient management.
METHOD AND DEVICE FOR OPERATING A HYBRID DRIVE

The invention relates to a method for operating a hybrid vehicle, comprising a parallel hybrid drive train (2) having an internal combustion engine (3), at least one electrical machine (5), at least one shift element (4), by means of which the at least one electrical machine (5) and the internal combustion engine (3) can be frictionally connected, a transmission (7) and a power take-off (26), the internal combustion engine (3) being startable from an electromotive driving operation. The aim of the invention is to allow an efficient and reliable driving operation, especially during starting of an internal combustion engine (3) from an electromotive travel, and to meet the requirements of travel comfort and driving dynamics of a person driving such a vehicle as far as possible. The method according to the invention is characterized by variably selecting, once a start demand for starting the internal combustion (3) is given, a starting mode from a group of available starting modes, using an evaluation of defined selection criteria depending on the current operating situation, and by initiating the respective starting mode. A device for carrying out said method comprises operating state detection and storage means (25) that communicate with an operating strategy unit (22) which is used to evaluate a current operating situation when the starting demand for starting the internal combustion engine (3) from an electromotive driving operation is received, and to select a start mode for starting the internal combustion engine (3) from a group of stored starting modes and to initiate it.
Collective approach of research and innovation for sustainable development in highland

The HIGHLANDS’ goal is to contribute to Inclusive Sustainable Development in Highlands (ISDH) through collective and impact-driven Research & Innovation (R&I), based on capacity building, sharing of local-global knowledge, experience, and tools. It will drive a co-innovation process through secondments and research and innovative sessions (R&IS) involving public/private and non-academic partners, to build a shared vision of ISDH, enhance the capacities of researchers, managers, users, policymakers, thus bridging the gap between research and development. Our activities will be organized in 5 integrated work packages (WP): Coordination & management (WP1); Methodology & capacity building for ISDH  (WP2); Analysis, comparison and modelling of ISDH (WP3); Building a multi-actor ISDH Decision-Support Platform (DSP) (WP4); Communication, Dissemination & Exploitation of results (WP5). HIGHLANDS is supported by a network of 43 institutions including 31 partners from Europe (~35% non-academic), and skilled and motivated female and male researchers and local stakeholders. The work plan will run 8 successive R&IS (5 in Europe, 3 outside) to promote the exchange among participants as a foundation for innovation. Each R&IS will build upon collective learning principles and a holistic systemic approach, exposing participants to a wide range of world views that will encourage experimentation with practice. Each R&IS will focus on a particular aspect of sustainable highland development and will include collective learning, collaborative research, and capacity-building on data collection/analysis, modeling. To complement the R&IS, long-term secondments will be implemented for researchers and practitioners to deeply train and work together on specific issues identified by the consortium. Collected data on ISDHs will be stored in an online collaborative and interactive decision-support platform that will then be transferred to existing mountain networks.
Renal function after intravitreal administration of vascular endothelial growth factor inhibitors in patients with diabetes and chronic kidney disease

The present study aimed to determine whether intravitreal administration of vascular endothelial growth factor inhibitors is associated with deterioration of renal function, as seen with systemic administration, in patients with diabetes and chronic kidney disease. Estimated glomerular filtration rates before and after 160 intravitreal injections of vascular endothelial growth factor inhibitors (aflibercept, bevacizumab or ranibizumab) were compared in 69 patients with diabetes and with a baseline estimated glomerular filtration rate <60 mL/min/1.73 m2 . We also determined the incidence of acute kidney injury. The data showed no significant difference in the estimated glomerular filtration rate before and after vascular endothelial growth factor inhibitor administration in all patients and in patient subgroups based on each inhibitor. Furthermore, no episodes of acute kidney injury occurred. In conclusion, intravitreal administration of vascular endothelial growth factor inhibitors is unlikely to be associated with a deterioration of renal function in patients with diabetes and chronic kidney disease.
Physiological Interpretation of the Slope during an Isokinetic Fatigue Test

To assess the relationship between selected measures (the slope and average performance) obtained during a high intensity isokinetic fatigue test of the knee (FAT) and relevant measures of anaerobic and aerobic capacities. 20 well-trained cyclists performed 3 randomly ordered sessions involving a FAT consisting in 30 reciprocal maximal concentric contractions of knee flexors and extensors at 180°.s−1, a maximal continuous graded exercise test (GXT), and a Wingate anaerobic test (WAnT). The slope calculated from peak torque (PT) and total work (TW) of knee extensors was highly associated to maximal PT (r=−0.86) and maximal TW (r=−0.87) measured during FAT, and moderately associated to peak power output measured during the WAnT (r=−0.64 to −0.71). Average PT and average TW were highly associated to maximal PT (r=0.93) and maximal TW (r=0.96), to mean power output measured during WAnT (r=0.83–0.90) and moderately associated to maximal oxygen uptake (0.58–0.67). In conclusion, the slope is mainly determined by maximal anaerobic power, while average performance is a composite measure depending on both aerobic and anaerobic energy systems according to proportions that are determined by the duration of the test.
New states of entangled matter out of equilibrium

When an extended quantum system is suddenly brought out of thermodynamic equilibrium all excitations collectively participate in the ensuing quench dynamics, causing a plethora of unconventional and exotic effects, in particular in low spatial dimensions where the effects of interactions and integrability are enhanced. The theoretical study of the non-equilibrium dynamics is hampered by the fact that the time dependent many-body wave function is highly entangled on spatial scales which rapidly grow in time. Consequently, a satisfactory description of the quench dynamics is a timely challenge whose solution cannot prescind from a precise characterisation of the entanglement content of the systems of interest.

The ambitious goal of this proposal is to find and characterise new non-equilibrium states of matter guided by their entanglement content. Two parallel lines of research will help achieving this goal. One line concerns the study of some entanglement indicators like entanglement Hamiltonian, spectrum, negativity and relative entropies which, contrary to the entanglement entropy, are not yet widely used as tools for investigating many-body systems. The other line focuses on the study of some frontiers of non-equilibrium one-dimensional physics which include quantum quenches in spinful fermionic systems, the determination of the exact time dependence of correlation functions after a quench, and the use of integrable hydrodynamics for investigating transport in one-dimensional systems. Particular attention will be devoted to the experimental realisation of the proposed non-equilibrium protocols. The main tools to achieve these goals will be conformal field theories and integrability complemented by numerical simulations when the former two are not applicable.
Localized corrosion studies for magnesium implant devices

The MAGPLANT project is intended to provide a major breakthrough towards the fabrication and application of bioresorbable Mg-alloy implants, which have the remarkable potential of accelerating bone healing while transferring the body’s mechanical load from the implant to the regenerating bone, as the Mg-alloy progressively degrades, thereby avoiding multiple surgical interventions. Moreover Mg is highly biocompatible as it is abundantly present in bone tissue and exhibits mechanical properties similar to those of bone.
Although there is currently much research on biodegradable Mg implants, the fundamental aspect for achieving success is controlling the corrosion rate of Mg-alloys in biological media. Because the main form of corrosion on Mg is localized corrosion, a thorough study consisting of localized electrochemical measurements must be performed. In the literature the biodegradable Mg is persistently being addressed as suffering from homogeneous corrosion, which is incorrect and does not provide the information on the microscopic processes occurring as the alloy degrades in contact with biofluids and cellular structures. In the scope of MAGPLANT the corrosion of Mg-alloys will be investigated by using modern localized electrochemical techniques. Therefore the underlying Mg-alloy corrosion mechanisms will be understood from the macro to the microscale level, considering the biological environments of interest.   
This project fits well into the key societal challenges for H2020 and will contribute to improve Europe’s research position on bioresorbable implants. Such perspective is well supported by the excellence and strong dedication of the host institution in the target research field, along with the research experience of the candidate.
Clinical perceptions of radiation therapy undergraduate competency standards

Introduction: The multifactorial nature of clinical skills development makes assessment of undergraduate radiation therapist competence level by clinical mentors challenging. A recent overhaul of the clinical assessment strategy at Queensland University of Technology has moved away from the high-stakes Objective Structured Clinical Examination (OSCE) to encompass a more continuous measure of competence. This quantitative study aimed to gather stakeholder evidence to inform development of standards by which to measure student competence for a range of levels of progression. Methods: A simple anonymous questionnaire was distributed to all Queensland radiation therapists. The tool asked respondents to assign different levels of competency with a range of clinical tasks to different levels of student. All data were anonymous and was combined for analysis using Microsoft Excel. Results: Feedback indicated good agreement with tasks that specified the amount of direction required and this has been incorporated into the new clinical achievements record that the students need to have signed off. Additional puzzling findings suggested higher expectations with planning tasks than with treatment-based tasks. Conclusion: The findings suggest that the amount of direction required by students is a valid indicator of their level and has been adopted into the clinical assessment scheme. Further work will build on this to further define standards of competency for undergraduates.
A customised low-cost ultralight aircraft for survey, filming and animal tracking in wild environments.

This proposal draws on the extensive technical developments of Ad-G 323041 LOCATE to commercialise the know-how to build a low-cost aircraft with integrated aerial survey, filming and tracking technology capable of operating in low-infrastructure environments. These requirements are common to many applications and there is currently no affordable off-the-shelf solution. Our product is unique, providing a technologically-advanced integrated data collection system controlled by a single pilot. Modular technology enables buyers to select options relevant to their own operation and minimise start-up costs. With operating costs of approximately €30/hour, our product will make sophisticated aerial survey, filming and tracking accessible to researchers, NGOs, government and commercial operators, delivering impact through high-resolution, high-quality information at low cost for infrastructure survey (eg pipeline, rail/cabling and flood plain survey) and conservation (habitat change, wildlife density), land and habitat management (national parks, game reserves). This aerial survey platform fills a market niche between drones (limited by payload and range) and commercial operations (high cost, require infrastructure, lack of flexibility). We will: DOCUMENT the structural modifications and specification for fitting out the aircraft with the equipment payload specified; REFINE the on-board systems set-up and mission planning system; DOCUMENT the options for modular on-board technology; DEVELOP a costing model for building, equipping, fitting out and operating the aircraft and licensing of IP; UNDERTAKE market analysis and research and communicate with potential suppliers and users; PREPARE a comprehensive portfolio for uptake by potential commercial partners. The project team includes three aviation/industry members experienced in bringing innovative technologies to this market.
Online Shopping Risks and effects on Consumers Purchasing Behavior

Despite the increase of the intention toward online shopping, the actual online shopping’s growth rate is still decreasing and the consumer’s behavior is the main gate to explain this phenomenon. The goal of this study is to investigate the effects of the perceived risk on the consumer purchasing behavior. The survey was distributed, whether in person or online, to 479 participants who had a previous experience about online shopping in order to apply the necessary statistical description methods, using SPSS software, such as frequencies, percentages and multiple regressions that will be used to test eight hypostasis. Findings show a significant negative effect of perceived risk as overall and its seven dimensions toward consumer purchasing behavior. To reduce the risk of online shopping , many factors that support the confidence and reduce the perceived risk that affect online shoppers, including build trust , privacy and security , the extent of information provided
Integrated biocircuits: engineering functional multicellular circuits and devices

Implantable neurotechnologies have revolutionized neuromodulatory medicine for treating the dysfunction of diseased neural circuitry. However, challenges with biocompatibility and lack of full control over neural network communication and function limits the potential to create more stable and robust neuromodulation devices. Thus, we propose a platform technology of implantable and programmable cellular systems, namely Integrated Biocircuits, which use only cells as the functional components of the device.We envision the foundational principles for this concept begins with novel in vitro platforms used for the study and reconstruction of cellular circuitry. Additionally, recent advancements in organoid and 3D culture systems account for microenvironment factors of cytoarchitecture to construct multicellular circuits as they are normally formed in the brain. We explore the current state of the art of these platforms to provide knowledge of their advancements in circuit fabrication and identify the current biological principles that could be applied in designing integrated biocircuit devices.We have highlighted the exemplary methodologies and techniques of in vitro circuit fabrication and propose the integration of selected controllable parameters, which would be required in creating suitable biodevices.We provide our perspective and propose new insights into the future of neuromodulaion devices within the scope of living cellular systems that can be applied in designing more reliable and biocompatible stimulation-based neuroprosthetics.
Synergistic interfacial properties of soy protein–stevioside mixtures: Relationship to emulsion stability

Abstract The dynamic interfacial tension and dilatational rheology of soy protein isolate (SPI) and stevioside (STE) mixtures at the oil–water interface were investigated to study the underlying stabilization mechanism for emulsions. The physical properties and long-term stability of emulsions prepared by SPI–STE mixtures were also evaluated. With bulk concentration of SPI fixed at 0.5%, the interfacial dilational properties and emulsion characteristics were markedly affected by the presence of low STE concentration (0.1%), although the interface was still dominated by SPI. With increasing STE concentrations to intermediate level (0.25–1%), synergistic effects in interfacial tension decays and a plateau in the elasticity for mixed SPI–STE interfaces were clearly observed. The effects should be mainly attributed to the formation of SPI–STE complex, enhancing interfacial protein–protein and protein–STE interactions, thus resulting in the presence of a plateau in the elastic behavior. These interfacial properties were positively reflected in the emulsions prepared by SPI–STE mixtures. The emulsions exhibited a fine formation ability and long-term stability after 120 days, which was believed to be due to their better response to external deformations. At high STE content (2%), STE dominated the formation of interface mainly by the preferential adsorption of STE molecules, as evidenced by the results of interfacial properties and surface protein load of emulsions. These findings would provide a potential strategy for designing emulsified foods with long-term stability.
Complexity reduction of the Kalman filter-based tracking loops in GNSS receivers

In modern GNSS receivers, using a Kalman filter in each signal tracking loop presents remarkable advantages in terms of accuracy and robustness against malicious noise sources, but poses critical issues in real-time applications due to the high computational cost. For this reason, we propose an efficient method to dramatically reduce the number of operations involved in the execution of the Kalman filter. In particular, the relationship between Kalman gain and noise covariances is analyzed in detail, showing that the gain computation can be greatly simplified by using an appropriately calibrated, small-size lookup table (LUT). The loss of performance of the proposed method, due to its inherent approximations, is shown to be negligible with respect to a traditional implementation upon careful system model and LUT calibration. Furthermore, a very fast signal tracking recovery after an outage is guaranteed. The implementation complexity of the simplified LUT-based method is compared with traditional approaches, proving that the proposed method has a tremendous advantage in terms of computational and storage requirements.
Lo scioglimento dei consigli comunali per infiltrazioni mafiose: effetti sulla politica e sull'amministrazione locale

L’articolo presenta i risultati di una ricerca sugli effetti della misura dello scioglimento dei comuni per infiltrazioni mafiose in Liguria attraverso l’analisi di tre studi di caso, guardando in particolare all’impatto relativo alla sfera politica e amministrativa. La ricerca si è avvalsa di un approccio qualitativo e ha utilizzato diverse fonti, tra cui documenti - come i Piani Triennali di Prevenzione della Corruzione e della Trasparenza dei comuni interessati dai provvedimenti di scioglimento , e interviste a osservatori privilegiati.