SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Effects of sleep deprivation and adrenergic inhibition on glymphatic flow in humans

Sufficient sleep is a key determinant of health, and sleep loss is associated with severe health risks. Nevertheless, the reason for why we sleep is not yet understood. Recently, a molecular function of sleep was described in rodents. The ‘glymphatic system’ (GS) is a sleep dependent macroscopic pathway of the brain that facilitates the removal of metabolites, including amyloid-beta. This project will for the first time reveal a sleep-driven human GS and show whether glymphatic flow (GF) can be linked to cognitive impairments associated with sleep loss. Secondly, I will promote GF with the adrenergic antagonist Carvedilol. This manipulation of glymphatic clearance may define new approaches for treating sleep-disorders and Alzheimer’s disease, or reduce or delay our need for sleep. 
I will investigate the human GS by applying state of the art, 5-10 Hz, ultra-fast MR sequences across sleep and wakefulness. Preliminary data show that these sequences enable the detection of cardiac, respiration, and slow pulsations, previously considered noise in fMRI imaging and distorted by aliasing effects. These pulsations are now believed to drive GF. The project will be a major step forward for sleep and neuroscience research, but also provide a key step in my career, demonstrating independent work and allowing me to learn advanced data-analysis skills and develop a novel imaging method, which I can apply in future studies. The chosen host institution is perfectly situated for the project, as they have established expertise and an exceptional skill-set in analyzing novel neuroimaging data including ultra-fast MRI. Secondly, my host provides unique infrastructure that allows for completion of the study, with key personnel in neuropsychology and data-analysis, as well as the world leading experts in glymphatic mechanisms. The project forms a foundation for a more general approach to integrate imaging of sleep-regulation and glymphatic mechanisms with patient or trait specific data.
A smile in return

The European e-commerce market amounts to ~80 million purchases per day. About 15% of purchased products do not live up to consumers’ expectations and are returned to the vendor. Whether in perfect condition or not, their status as returned product makes items suddenly worth a lot less. What a waste! Not only to e-tailers, who typically lose +80% of the value of returned products, but also to the environment, which is impacted by 4 billion pounds of disposed products and 11 million metric tons of carbon emissions. The problem is expected to grow as ecommerce is gaining market share fast (13.3% growth in 2016).
BuyBay helps to solve the problem. The tech-company is developing a data-driven solution that revolutionises the management, processing and resale of returned items. It uses highly innovative pricing software and is unique in its ability to connect inventory management and re-product grading to multiple third party sales channels. 
The prototype of the Buybay platform is complete and qualified and has recently been tested in in real world settings in the Netherlands and Belgium. Demonstrations have shown that Buybay’s prototype platform has potential for unmatched value recovery (~56% instead of 19.6% of the original retail price currently). Installation of BuyBay’s platform increases re-product revenues for e-tailers, reduces the need to dispose of returned goods and has the potential to reduce re-product selling related carbon emissions of up to 31%. 
To ensure complete commercial scalability and enable international acceptance by e-tailers of different sizes and in different sectors across Europe, Buybay’s platform requires additional infrastructure development, optimisation through businesses intelligence analysis and scale up testing in operational environments. With the support of leading international etail companies Buybay aims to develop the new standard for returned goods.
ESTUDO DO COMPORTAMENTO DA ESCÓRIA DE ACIARIA TIPO LD EM BASE DE PAVIMENTOS URBANOS

Uma das principais dificuldades encontradas pelas indústrias atualmente refere-se à destinação dos resíduos. As indústrias siderúrgicas fomentam e demonstram grande esforço para encontrar alternativas de reutilização. A escória de aciaria tipo LD (Linz Donawitz), subproduto proveniente da produção do aço, possui características mecânicas semelhantes aos materiais naturais utilizados na indústria de pavimentação, porém alguns estudos apresentam como fator limitante ao seu uso, seu alto teor de expansão. As escórias de aciaria possuem grande potencial de aplicação, por exemplo, como corretivo do solo, em lastro de ferrovias, no tratamento de águas ácidas e na indústria cimenteira. Com esta pesquisa, pretende-se dar ênfase a uma destinação de resíduos industriais na execução de obras de engenharia de terraplanagem, para substituição de materiais naturais. A escória de aciaria tipo LD utilizada neste trabalho é um coproduto denominado REVSOL, desenvolvido pela empresa ArcelorMittal, que será caracterizado física e quimicamente. Este trabalho procura analisar o desempenho físico-mecânico de misturas de solo-escória de aciaria. A primeira etapa compreendeu a caracterização física do REVSOL, do solo e da mistura solo-REVSOL, e análise química do REVSOL. Na segunda etapa, realizaram-se ensaios de Índice de Suporte Califórnia (ISC) do solo e da mistura solo-REVSOL, e expansão da mistura pelo método PTM 130/78 (Pennsylvania Testing Method, USA), objetivando comparar os resultados obtidos com as exigências das normas do Departamento Nacional de Infraestrutura de Transportes (DNIT) de execução de bases granulares para pavimentos flexíveis. Os resultados obtidos demonstram que as misturas solo-REVSOL têm viabilidade de uso na execução de base para pavimentos.
Terrestrial Animal- and Plant-Based Ingredients as Alternative Protein and Lipid Sources in the Diets for Juvenile Groupers: Current Status and Future Perspectives

The Epinephelinae groupers are strict carnivorous species. They are widely cultured in the Asia Pacific region as a result of high demand and market price especially in the live reed food fish trade. Groupers are commonly raised in net cages and fed with the unsustainable low value fish. Although this feeding practice has been gradually improved by using formulated diets, the production cost of these diets is high due to the increasing prices of fish meal and fish oil. In order to find sustainable replacements for these expensive commodities, research has been conducted to evaluate alternative ingredients effects on fish growth performances and immune function. This review covers different types of alternative ingredients tested on several species of juvenile grouper. In general, animal protein sources were able to replace fish meal at higher inclusion levels than plant protein sources. Lowered digestibility, deficiency in essential nutrients, and reduced palatability are major challenges in using alternative ingredients in grouper feeds.
What Does In-Work Poverty Mean for Women: Comparing the Gender Employment Segregation in Belgium and China

This article presents an analysis of the female working poor in relation to gender employment segregation. It draws a cross-national profile of the female working poor in Belgium and China: two different nations with distinct stories of socio-economic development and cultural heritage, while both are characterized by high female employment participation. Analyses show that (1) women share a higher proportion among the total working poor population in both nations during recent years, whereas (2) in-work poverty has been a chronic condition, particularly among female workers in low-quality jobs. Thus, to some extent, labor market institutions may shape this gendered tendency of in-work poverty. In this article, women’s position in the public sphere in relation to employment segregation is discussed, and a contextual analysis identifies the causes of gender employment segregation. The results shed light on the crucial role of gender employment segregations related to in-work poverty and show that gender ideology and stereotypes do matter in explaining such employment differences. We argue that the promotion of female participation should be combined with explicit measures to reduce the disadvantageous position of women in the labor market.
Hallazgo de Dactyloidites ottoi (Geinitz, 1849) en la Arenisca de Aren (Cretácico Superior surpirenaico)

En el Cretácico Superior de la Arenisca de Aren (cuenca surpirenaica) se registran pistas fósiles atribuidas a Dactyloidites ottoi (Geinitz, 1849) en sedimentos marinos de estuario con influencia de mareas. Las pistas en forma de roseta tienen 12-20 radios rectos o asimétricamente ramificados, con una sección constante de unos 5 mm, que cubren unos 200° de círculo. Este icnotaxón, producido por un animal sedimentívoro desconocido, ha sido también encontrado en facies similares en sedimentos del Cretácico Superior en Alemania, Japón y Groenlandia, y en areniscas del Neógeno de Borneo, España y Jamaica. Los hallazgos apuntan hacia un organismo productor habitante de medios de estuario inferior en climas tropicales.
REVERSIBLE BELT TIGHTENER

The invention relates to a reversible belt tightener comprising: - an electric motor (2); - a belt shaft (1) onto which a safety belt can be wound; - a driving wheel (10) that is coaxial to the belt shaft (1); and - a coupling (11) between the belt shaft (1) and the driving wheel (10). The electric motor (2) includes a protruding drive shaft (12) via which the electric motor (2) is connected directly to the driving wheel (10).
Innovative design of acoustic treatments for air conditioning systems: from laboratory to an industrially-relevant environment

ONERA, the French Aerospace Lab, and the two SMEs ATECA and Poly-Shape will combine their research and technological capabilities to propose new ideas in the domain of acoustic liners and in-duct modal detection for air conditioning systems. A modal detection tool adapted to the industrial setup will be proposed and manufactured, to assess the noise source created by the jet pumps of the air system. A compact innovative acoustic liner will be designed in order to mitigate this noise source all over the frequency range, while meeting the strict weight, costs and tight space restrictions. The consortium will benefit of the numerical and experimental capabilities of ONERA, as well as of the complementary technological capabilities of the two SMEs ATECA and Poly-Shape regarding advanced materials & direct manufacturing. The long experience of the partners on these activities will allow to mature innovative liners technologies, and to bring these new concepts from the research laboratory to an industrially relevant environment, ie from TRL 3 to TRL 6, through a close cooperation with the Topic Manager.
MAIN GROUP METAL COMPLEXES AS P-DOPANTS FOR ORGANIC ELECTRONIC MATRIX MATERIALS

The present invention relates to a main group metal complex of groups 13 to 16 comprising at least one ligand of the structure (I), where R1 und R2 can be, independently of each other, oxygen, sulfur, selenium, NH or NR4, where R4 is selected from the group consisting of alkyl or aryl and can be connected to R3; and R3 is selected from the group consisting of alkyl, long-chain alkyl, alkoxy, long-chain alkoxy, cycloalkyl, halogenalkyl, aryl, arylene, halogenaryl, heteroaryl, heteroarylene, heterocycloalkylene, heterocycloalkyl, halogenheteroaryl, alkenyl, halogenalkenyl, alkynyl, halogenalkynyl, ketoaryl, halogenketoaryl, ketoheteroaryl, ketoalkyl, halogenketoalkyl, ketoalkenyl, halogenketoalkenyl, wherein in suitable radicals one or more non-adjacent CH2-groups can be substituted independently of one another by -O-, -S-, -NH-, -NR°-, -SiR°R°°-, -CO-, -COO-, -OCO-, -OCO-O-, -SO2-, -S-CO-, -CO-S-, -CY1=CY2 or -C=C-, specifically in such a way that O and/or S atoms are not connected directly to one another, are likewise optionally substituted with aryl- or heteroaryl preferably containing 1 to 30 C atoms, as a dopant for matrix materials in organic electronic components.
Antenna apparatus

Disclosed is an antenna apparatus including: an antenna element including a receiving unit to receive an electric wave; a circuit substrate including a circuit surface on which a circuit amplifying an input from the antenna element is formed; a shield cover covering the circuit surface to shield the circuit substrate from a disturbing wave, the shield cover being grounded; a coaxial cable to supply driving power and GND potential to the circuit, and to output a signal from the circuit, the coaxial cable inserted into the shield cover, wherein the shield cover includes a base surface disposed in parallel with the circuit surface and a tongue flap extending to the coaxial cable, and the tongue flap includes a connecting piece formed by bending an end of the tongue flap at a side of the coaxial cable, the connecting piece being soldered to an outer conductor of the coaxial cable.
Macro and microelements in bottled and tap waters of Serbia

Comparative analysis between bottled and tap waters as well as its comparison with current Serbian regulations, European Union Directives and World Health Organization standard are shown in this paper. Thirteen bottled waters and fourteen tap waters from the territory of Serbia were analyzed in the Federal Institute for Geosciences and Natural Resources (BGR) laboratory in Berlin, for the purpose of the ?Geochemistry of European Bottled Water? project conducted by EuroGeo Survey Geochemistry (EGS). Macrocomponents (main cations and anions) of ground waters usually reflect on lithogeochemistry of the aquifer, while microcomponents indicate the circulation of ground water through the different lithological environment. Analyzed bottled waters could be classified as those with low mineral content (M&lt;500 mg/L) if HCO3 anion and Ca and Mg cations were the prevailing ones, or mineral (M&gt;500 mg/L) with prevailing HCO3 anion and Na cation. Waters with low mineral content were mainly from limestone and dolomite, while mineral waters mainly originated from magmatic and metamorphic rocks. Higher content of Cs, Li, Ge, Rb and F in bottled waters indicates the importance of the magmatic intrusions influence on their chemical composition. In some waters higher content of B, I, NH4, as well as of Tl and W has been observed which can be attributed to water?s circulation through different lithological complexes. Tap water was mostly obtained from groundwater (from Neogen and alluvial aquifers and karst springs) with rest being those of rivers and surface accumulations. Tap waters from Central Serbia were with low mineral content, with prevailing HCO3 anion and Ca and Mg cations, while waters from Vojvodina, the northern province of Serbia, were with higher mineralization, HCO3-Na. Chemical analyses of the sampled tap waters showed good quality, with exception of waters from the cities of Senta and Zrenjanin in Vojvodina. High values of B (1170 and 895 g/L), As (20.9 and 71.9 g/l), Na (208 and 275 mg/L), as well as EC (715 and 928 S/cm) have been registered in these waters.
Catalytic dual-function devices against cancer

Despite intense research efforts in almost every branch of the natural sciences, cancer continues to be one of the leading causes of death worldwide. It is thus remarkable that little or no therapeutic use has been made of a whole discipline, heterogeneous catalysis, which is noted for its specificity and for enabling chemical reactions in otherwise passive environments. At least in part, this could be attributed to practical difficulties: the selective delivery of a catalyst to a tumour and the remote activation of its catalytic function only after it has reached its target are highly challenging objectives. Only recently, the necessary tools to overcome these problems seem within reach.
CADENCE aims for a breakthrough in cancer therapy by developing a new therapeutic concept. The central hypothesis is that a growing tumour can be treated as a special type of reactor in which reaction conditions can be tailored to achieve two objectives: i) molecules essential to tumour growth are locally depleted and ii) toxic, short-lived products are generated in situ.
To implement this novel approach we will make use of core concepts of reactor engineering (kinetics, heat and mass transfer, catalyst design), as well as of ideas borrowed from other areas, mainly those of bio-orthogonal chemistry and controlled drug delivery. We will explore two different strategies (classical EPR effect and stem cells as Trojan Horses) to deliver optimized catalysts to the tumour. Once the catalysts have reached the tumour they will be remotely activated using near-infrared (NIR) light, that affords the highest penetration into body tissues. 
This is an ambitious project, addressing all the key steps from catalyst design to in vivo studies. Given the novel perspective provided by CADENCE, even partial success in any of the approaches to be tested would have a significant impact on the therapeutic toolbox available to treat cancer.
Non-isothermal kinetic study of CO2 sorption and desorption using a fluidizable Li4SiO4

Abstract This study considers the CO 2 sorption–desorption kinetics on a promising acid treated fluidizable Li 4 SiO 4 sorbent. To accomplish this both carbonation and decarbonation including dynamic the thermodynamic equilibrium are considered using Temperature Programmed Carbonation (TPC) and Temperature Programmed Decarbonation (TPDC) experiments. The proposed phenomenological based kinetics model is established by comparing its suitability using correlation coefficients ( R 2 ), lowest sum of squares (SSQ) of residuals, parameter spans for the 95% confidence interval and cross-correlation coefficients matrix. It is found that a Langmuir Hinshelwood Model (LHM) is the best to describe the CO 2 adsorption on Li 4 SiO 4 , while a Nucleation and Nuclei Growth Model (NNGM) with three dimensional growths is required to model the CO 2 desorption process. On this basis, it is speculated that the CO 2 adsorption rate over the acid treated porous fluidizable Li 4 SiO 4 is dominated by a surface reaction, while the CO 2 desorption rate is ruled by the formation and three dimensional growths (as hemisphere) of nuclei.
PRESSURIZED ACTUATOR

A linear actuator 10 contains a housing 12 having a first end 14 and a second end 16. A hollow piston rod 23 is positioned within the housing 12 to slidably engage with an inner wail 25 of the housing 12. A sealed gas chamber 30 is formed within the hollow piston rod 23 and contains stored gas 33 tor driving the piston rod 23 upon activation of the actuator 10.
In-Situ spatiotemporal imaging of membrane hydration, electrostatics, tension and curvature to understand cell response to osmotic shocks and cell migration.

Lipid membranes compartmentalize and protect cells from the environment, and selectively permit transport. This functionality derives from unique membrane properties: 5 nm thick, yet fluid, deformable, resistant to stress and chemically complex. The physicochemical properties of membranes are expected to have a major impact on cell life, but the tools to measure the relevant multiscale and dynamic parameters in-vitro and, more importantly, in-vivo membranes are lacking. An essential property of membranes, their hydration and charge state, both needed for membrane integrity and playing a vital role in cell survival is not understood beyond the level of continuum theory. To enable quantitative physics, and physical chemistry for biology Roux and Roke, R^2, will join their expertise on molecular biology & biophysics and physics & interfacial chemistry & optics to create tools to measure membrane water and ion fluxes, and image 3D fields of electrostatic free energy, membrane tension and curvature. We will understand how molecular factors, such as the influence of the aqueous phase and interfacial electrostatics, are coupled to tension and curvature under dynamic conditions such as osmosis in artificial and cellular membranes. Obtaining the first temporally resolved, 3D maps of hydration, free energy, tension and curvature at the nanoscale in migrating cells and cells experiencing osmotic shocks we will quantify membrane physical parameters in two processes essential for cell survival, for which currently no data is available: Osmotic shock response and cell migration. Osmotic shock response plays an important role in infections, kidney and intestine function. Cell migration is essential to many cell processes, for example the spreading of cancer, wound repair and the immunological response, as well as food search in unicellular organisms.
Improvements in connection with the Manufacture of Ammonia.

9841. Johnson, J. Y., [Badische Anilin & Soda Fabrik]. April 25. Catalytic materials.-A catalyst for use-in the synthesis of ammonia, consisting of pure iron or pure iron nitride, is prepared by passing an excess of ammonia over an iron compound at a temperature materially above 600 C. An excess of ammonia is defined to be an amount greater than that which corresponds to the equilibrium concentration for the temperature employed. In an example, a temperature of 800 C. is used in conjunction with a quicklymoving current of ammonia gas.
Foodborne infections and intoxications in Poland in 2008

A total of 12 217 bacterial foodborne infections and intoxications were registered in 2008 (incidence 32.1/100 000 population). Unlike bacterial infections, the incidence of viral foodborne infections increased in the recent years (2008 - 85.4 vs. 2007 - 57.1; 2006 - 54.21; 2005 - 32.8, and median 2002-2006 - 27.2). In 2008 were notify of 480 foodborne infections and intoxications involving 5788 cases (only outbreaks involving 4 person or more) and 138 foodborne (involving 2-3 persons). S. Enteritidis were the most frequency etiological agent in outbreaks (94.2% of outbreaks 89.3% cases in outbreaks). The main vehicle of foodborne outbreaks in 2008 were food prepared eggs (19.6% of outbreaks, 12.3% cases). Private homes were the most prevalent among the places of food contamination (13.2% of outbreaks). The tree epidemics with 100 or more cases each, were registered (one caused by Norovirus and two by Bacillus cereus) involved 564 cases.