SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Poplar root exudates response to multi-nutrients stress

In the face of global changes, agroecosystem productivity is essential both for CO2 fixation and feeding the increasing population. However, plant growth is frequently limited by nutrient availability and in the environment, plants are more often exposed to multiple than single nutrient deficiencies. Plant responses to single nutrient deficiencies have been widely studied while the combined effect of different nutrient deficiencies has been scarcely investigated, particularly for tree species. Root exudates comprise a complex mixture of organic compounds, directly involved in the biogeochemical cycles of nutrients in soils, it can be assumed that their quantity and quality are affected by combined nutrient deficiencies in a different way than under a single one. Thus, this proposal aims to profile Poplar (a fast-growing tree) root exudates under single and combined deficiencies, mainly focusing on: (1) N for macronutrient deficiency as the most often limiting nutrient and on Fe, Zn, and Mn as micronutrients because of their crucial role in photosynthesis, (2) experiments on mineral deficient calcareous soils close to agronomical situations and (3) testing the potential of Poplar root exudates to alleviate nutrient deficiencies in sensitive species such as fruit trees growing on  calcareous soils. The applicant has a very strong background in soil chemistry and plant nutrition acquired during her MSc and Ph.D., which together with the experience and facilities of the host and the international supervisory team will lead to the successful completion of this project and the strengthening of the career development of the researcher. The interdisciplinary work involving plant physiology, metabolite profiling, and chemoinformatic tools will lead to (1) improve knowledge about root exudation under nutritional stress and (2) open a new perspective on root-root interactions that can improve plant nutrition.
Secondary prevention of cardiovascular disease in the elderly trial

While Cardiovascular diseases (CVD) are the main cause of death worldwide, they are responsible for half of all deaths in Europe. The overall ageing of the European population and improving survival of patients with coronary heart disease has created a large population of older adults eligible for secondary prevention. Despite the established efficacy of cardiovascular medications, suboptimal adherence reduces their effectiveness and is the primary reason for suboptimal clinical benefit, contributing significantly to worsening of diseases and deaths at the population level. SECURE will be the first trial testing the efficacy of a fixed dose combination (FDC) polypill for secondary cardiovascular prevention in the elderly population (≥ 65 years old). The main objective is to evaluate the potential benefit of the FDC as a component of a cost-effective, globally available and comprehensive treatment strategy for secondary prevention of cardiovascular events (death from cardiovascular causes, nonfatal myocardial infarction, stroke, and hospitalisation requiring revascularisation) as compared to standard therapy (the three components of the polypill given separately). As part of the secondary endpoints, SECURE will compare the effect of both strategies on adherence and intermediate measures of risk factor control such as lipids and blood pressure. Importantly, it will also measure the pharmacoeconomic impact of the FDC intervention as well as regional differences in all outcomes. The five-year project will thus involve subjects from seven different countries: Spain, Italy, France, Germany, Hungary, Poland and the Czech Republic. The findings and conclusions obtained in SECURE will allow the drafting of clinical guidelines and recommendations that will provide useful guidance and will serve as a reference framework for all stakeholders involved in tackling major challenges related to secondary prevention and treatment of chronic diseases in the elderly population.
Konseptstudie for levetidsforlengelse i konstruksjoner

In light of the current situation on the Norwegian continental shelf with respect to the increase in the number of aging facilities, there is currently a great need for knowledge about the challenges of aging mechanisms and lifetime extension. The challenges of operating beyond the design lifetime is not due to the SSC's specific age, but to operations and maintenance organizations' ability to predict and verify the condition of the individual SSC, as well as their ability and willingness to perform proper maintenance. In the nuclear industry has this problem been on the agenda since the late 70's, this to verify if it was technically safe to operate the power plants beyond the 40 year operational limit. The question that needed to be answered was whether the aging effects could be handled in a responsible manner so that power plants could operate within the original safety margins in the extension period. To answer this question, it was put into effect several research projects to determine the effect of aging on nuclear power plants. Over time, the information from these projects has been used to develop and improve a system for evaluating safe implementation of life extension for nuclear power plants. To increase knowledge about aging mechanisms, it is important to establish maintenance systems that capture trends of degradation in SSC’s. On behalf of this documentation it will be possible to develop new state of the art evaluation systems for verification of condition. In addition, it would be natural to maintain the exchange of experience between industries with similar issues such as the nuclear power industry. For load-bearing structures are the greatest challenges in the operational phase associated with the verification of integrity, after either modifications that provide load changes in structure, or degradation and modifications that change the capacity of the structure. In addition, it may be difficult to update the analysis in accordance with the regulatory changes for load calculations, and to implement the updated meteorological data such as wave loads, ocean current and wind. The capability to establish good structural analysis models are therefore entirely dependent on exact status data and documentation from design, fabrication and installation phase. At the condition assessment of the load-bearing structures, there will also be important with accurate inspections. The reason for this is that the aging mechanisms can occur in all phases of the design life of the load-bearing structures, this is due to variations in operating environment and stresses that it is not taken into account in the design criteria. Therefore the focus of life extension concept for load-bearing structures should be at risk management, through the use of updated analytical models for the structure based on the DFI-, inspection- and maintenance data. For load-bearing structures the notion of safe operating time should be used rather than design life. This is because the design life will be object of change as a result of updated status data, re-analysis and regulatory changes.
Precision cancer medicine pipeline and services

Cancer cost the EU €126 billion in 2009, while in 2010 the US spent a staggering $124.6 billion on treating cancer.  This cost is set to rise as the effects of an aging population and increasing life expectancy take their toll. These market drivers will put an intolerable strain on health services across the western world, forcing governments to streamline their health services. 
Current cancer treatment is based on the ""average cancer patient"", meaning some cancer patients may not respond to the treatment while others do. Thus it is clearly is a need for solutions that offer precision cancer medicine.

PubGene AS aims to pursue a major market opportunity by developing a complete pipeline for precision cancer medicine (PCMPS), that include the necessary steps from Next Generation Sequencing to clinical treatment support for cancer patients. The biggest beneficiary of PCMPS will be the patient, who will receive a personalized treatment rather than a “hit and miss” approach to therapy. This will improve patient outcomes and ensure patients no longer have to suffer harsh side effects from non-efficacious treatments. The second beneficiaries will be the health providers and payers, as doctors will no longer waste time and money prescribing ineffective treatments. Nevertheless, despite the benefits of personalized cancer medicine, it is crucial to validate and demonstrate the benefits of this type of cancer medicine before large-scale commercialization.

PMCPS is an opportunity for PubGene to expand our suite of applications and enter into complete new market for PubGene - targeting the treatment market. The project will give us a head start in providing tools in the field of personalized cancer medicine, ensuring us strong positions in the future European and worldwide markets. Accomplishment of the project will represent a significant business opportunity with an expected annual turnover of €17 million with a 25-30% annual increase, 3 years after commercialization.
Metropolitan Agriculture for Developing an innovative, sustainable and Responsible Economy

According to the FAO, a paradigm shift in both urban and agriculture development, planning and policy formulation is required in order to ensure access to urban food security, improved environmental management and enhanced rural-urban linkages. Although recognized as a major lever of eco-innovation for metropolis' sustainability and competitiveness, metropolitan and periurban agriculture (MPA) still suffers from a "mainstreaming gap", remaining overlooked by policy makers, academic research and the general public. As a result, the environmental price of food is an invisible but nonetheless major burden for cities. The MADRE project aims to meet this challenge : supply MPA with key players (from the quadruple helix) and create a transnational cooperation in the MED aerea. Aiming at fostering a change process in the metropolitan food supply model, the project will capitalize on the wide set of academic knowledge, pilot actions and policies, networks and transnational cooperations in order to allow MPA reaching a critical level in the MED area. Indepth assessment of available material will provide the baseline for an empowerment of MPA stakeholders and then to a formal committment to initiate a transnational clustering processs. Such a capitalization process will involve a multidisciplinary, pluralistic and multilevel partnership from 4 different MED countries (Spain, France, Italy, Greece) and Albania (IPA), each partner representing a flagsghip metropolitan area.
Young, James and Itihari Toure, Eds.: Asa: Honoring His Life and Work

Young, James and Itihari Toure, eds. Asa: Honoring His Life and Work. Chicago, IL: African American Images, 2013. ISBN: 978-1934-155-844, pbk, bib, pp.154. [ILLUSTRATION OMITTED] A collection of essays by Itihari Toure (Clark Atlanta University; The Jenga Collective), Chike Akua (Georgia State University), Mark A. Lomax (First African Presbyterian Church, Lithonia, Georgia), Charlyn Harper Browne (Center for the Study of Social Policy, Washington, D.C.), Ernest D. Washington (University of Massachusetts, Amherst), James C. Young (Clark Atlanta University), and Sarita K. Davis (Georgia State University, Atlanta) in honor of the life and work of teacher, historian and psychologist Asa G. Hilliard (Nana Baffour Amankwatia, II), Ed.D. Hilliard (1933-2007) served as an endowed professor of Urban Education at Georgia State University in Atlanta for twenty-seven years, led numerous study tours to Egypt and Ghana for over thirty years, authored several books and hundreds of articles, and was a founding member of the National Black Child Development Institute and (first vice-president) the Association for the Study of Classical African Civilizations. The book is organized around issues facing the survival of the African (p.iv) throughout the world, and thus, it is designed to engage critical thinking and inquiry formulated on a paradigm of reawakening the African mind through re-socialization, infusion, mastery and the dissemination of a transformative African-centered education (pp.3-4). In chapter one, Toure frames the discourse to suggest that educational excellence was the mission of Hilliard's work, hence an Asafication of excellence that would 'locate African people' in the context of cultural excellence wherein the production of excellence would be the norm and building for eternity an expected goal (pp.1-2). Next, in chapter two, Toure discusses restoring excellence in African education, renewing a process of social transformation, specific models of communal healing excellence, and spiritually driven and conceptualized collective experiences personified in the Jegna Collective community developed transformation process. Chike Akua via a series of letters from his former students outlines that education has been a cultural thread in the African American community that reflects the ancient African philosophy of education and he ends with a definition of African-centered education in chapter three. Mark A. Lomax discusses Christian spirituality in the context of leadership in the church in North America in a rambling way to suggest that self-hate and self-deprecation is retarding the African American community; Charlyn Harper Browne in a genetic manner details the importance of preparing early childhood educators and states that perhaps the most important lesson she learned from Hilliard was to never stop questioning, reading, reflecting [and] searching for meaning, and learning in chapter five (p. …
APPARATUS FOR CLOSING MOUNTING TUBES WATERTIGHTLY

The invention relates to an apparatus for closing mounting and casing tubes watertightly in buildings where water and/or heating lines (2) are mounted inside mounting and casing tubes (5) and where connection pieces (4), which are placed inside connection boxes (1), are used for connecting e.g. water fixtures to water lines. The connection box (1) contains a through opening (3) leading to at least one jointing element (6), by means of which a watertight jointing of the mounting and casing tube (5) can be accomplished. The connection box (1) is provided with a continuous circumferential shoulder (9) on the inside thereof for a washer (10) and the connection piece (4) is provided with a continuous circumferential flange (7). In the assembled form of the apparatus, said flange (7) is arranged to position against said shoulder (9) and the washer (10) therebetween is fitted to press against said elements and close the connection box (1) watertightly.
Interactive machine learning for compositional models of natural language

INTERACT will develop new Interactive Learning Algorithms (ILA), motivated by applications in Natural Language Understanding (NLU). The main assumptions behind supervised approaches are unrealistic because most NLU applications have unique information needs, and large collections of annotated data are necessary to achieve good performance. INTERACT follows a collaborative machine learning paradigm that breaks the distinction between annotation and training. We focus on compositional latent-state models (CLSMs) because natural language is rich, complex and compositional. To reduce the amount of human feedback necessary for learning CLSMs we must eliminate annotation redundancy. We argue that to achieve this in the context of CLSMs we must combine: (1) An optimal human feedback strategy, with (2) inducing a latent structure of parts in the compositional domain. Annotation effort will be minimized because the method will only request representative feedback from each latent class. INTERACT marries representation learning (i.e. of parts) and active learning for CLSMs.

Our approach goes beyond classical active learning where the ILA asks labels for samples chosen from a pool of unlabeled data. We empower the ILA with the ability to ask for labels for any complete or partial structure in the domain, i.e. the ILA will be able to generate samples.

We work under the framework of spectral learning of weighted automata and grammars and use ideas from query learning. A key idea is reducing the problem of interactive learning of CLSMs to a form of interactive low-rank matrix completion. Our concrete goals are: (1) Develop ILAs for CLSMs based on spectral learning techniques; and (2) Investigate optimal strategies to leverage human feedback, taking into account what is optimal for the ILA and what is easy for the teacher.

We will experiment with NLU tasks of increasing complexity, from sequence and tree classification to parsing problems where the outputs are trees.
Production of plant natural products through engineered Yarrowia lipolytica

Plant natural products have broad applications in the pharmaceutical, food, cosmetics and flavor industries. However, the current manufacturing methods for plant natural products mainly rely on plant extraction and chemical synthesis, which are associated with unsustainability and severe environmental problems. The advancement of genetic technology has facilitated the engineering of microbes for producing plant natural products, but their industrial production titers remain low. Yarrowia lipolytica, a nonconventional yeast, is a promising and superior host for plant natural products manufacture, due to its advanced properties compared to conventional hosts. In this review, metabolic engineering approaches recently employed for overproduction of useful plant natural products, including terpenoids and polyketides, in Y. lipolytica are summarized. The current challenges for the biosynthesis of typical compounds are discussed and promising engineering strategies for future work are also suggested. This review provides guidance for engineering Y. lipolytica as a robust host for plant natural products production.
DISPOSITIF LOGIQUE PROGRAMMABLE DE PRISE, TRAITEMENT ET TRANSMISSION DE DONNEES

<P>LE DISPOSITIF LOGIQUE COMPORTE TROIS MEMOIRES 1, 2, 3 CONTENANT RESPECTIVEMENT DES MOTS-INSTRUCTIONS 1, DES MOTS-GRILLE 2 PERMETTANT DE PRENDRE EN CONSIDERATION TOUT OU PARTIE D'UN MOT ET DES PAIRES D'ADRESSES 3 DEFINISSANT DES ELEMENTS-SOURCES OU DESTINATIONS A METTRE EN COMMUNICATION, ET UN COMPARATEUR LOGIQUE 10 PERMETTANT DE SAVOIR SI UNE CONDITION EST REALISEE POUR LA FAIRE SUIVRE D'UNE ACTION. LES MEMOIRES 1, 2, 3 SONT EXPLOREES CYCLIQUEMENT 4 ET EN SYNCHRONISME. UN PREMIER BUS 6 PERMET LA COMMUNICATION SOIT D'UNE ENTREE 8 AVEC LE COMPARATEUR 10, UN REGISTRE 11 OU UNE SORTIE 9. UN DEUXIEME BUS 12 APPLIQUE LE MOT-GRILLE 2 AU COMPARATEUR 10, A UN REGISTRE 11 OU A UNE SORTIE 9. UN TROISIEME BUS 15 AMENE LES ADRESSES 3 AUX ENTREES ET SORTIES 8, 9.</P><P>L'INVENTION S'APPLIQUE A LA PRESENTATION DE RESULTATS OU LA COMMANDE D'ACTIONS SUR LA BASE DES INFORMATIONS QUI LUI SONT FOURNIES.</P>
X5 bitworker - the copying system for the internet of things and industry 4.0

The software of products plays a more and more increasing role. It is placed on different types of data carriers (e.g. USB, Compact Flash, SD Card) which are assembled in each of these products (e.g. car infotainment system, washing machine, toys). Digitalisation provides opportunities like customisation and interconnectivity and is basis for applications in Internet of Things and Industry 4.0, but also opens up huge security leaks. The X5 solution secures the product software and its know how and protects them from data theft and hacking attacks.

In the past 2 years, X-Net developed the globally unique solution named X5 to assemble customised software on each product for its key customers BOSCH and NOVOMATIC. This enabled in-house and in-line production and individualisation of product software. But most of all it additionally helps to protect European product software (where today most of the know how is based) through unique encryption.

The reference installations at BOSCH and NOVOMATIC demonstrate requirements, impact and potential of a fully integrated production with worldwide highest security level. The know how X-Net gained through that is very important for other European and global companies, too. SME instruments should help to build up the market for this solution and bring the expertise to these companies having high needs. X-Net will roll out the X5 solution in Europe and further on globally. Yearly revenues of about 14 million EUR in 2019 and 78 million EUR in 2021 are expected.
Effective Teaching System Building of Applied Engineering Colleagues

In order to improve the teaching quality of Local applied engineering colleagues,this paper proposes to build an effective teaching system for the local applied engineering colleagues.Firstly,combined with the local applied engineering colleague,the connotation of effective teaching is given.Then on the basis of the investigation that such colleges and universities,in the whole teaching and learning environment,build an effective teaching system presented from four aspects:the focus on effective classroom teaching,strengthen effective after-school practice and practice and do a good job of effective assessment and to strengthen the management of flexible teachers.In this way,the system can ensure a gradual increase of the teaching level and the overall quality enhancement of all students of the local applied engineering colleagues.
Improved Regional Tourism Carbon Footprint Measure Model and Zhangjiajie Empirical Research

Because of lacking of the statistics of the Tourism Satellite Account,the research on carbon footprint in composition method is given priority to others. When using component method to measure the carbon footprint model,more sufficient the consumer items are to be considered,more close to the real carbon emissions the result is. The statistical accuracy of the results depends on the integrity of the ingredients list and the valuation of the various components of the project life cycle. The paper is going to establish the calculation model of the regional tourism Carbon footprint,by using the composition method of cost model and life cycle model. The region tourism Carbon footprint is divided into three parts: Carbon footprint in the tourism development; Carbon footprint in the tourism consumption; Carbon footprint in the tourism waste disposal process. The result of empirical analysis to the Zhangjiajie tourism greenhouse gas emissions shows that Zhangjiajie tourism industry belongs to the low carbon tourism.
The complete mitochondrial genome of Accipiter virgatus and evolutionary history of the pseudo-control regions in Falconiformes

Abstract The complete mitochondrial genome sequence of Accipiter virgatus was determined. This mt-genome was 17,952 bp in length and consisted of 22 tRNA genes, 13 protein-coding genes, 2 rRNA genes, one control region (CR) and one pseudo-control region (CCR). Phylogenetic analyses of 14,644 bp of mitochondrial DNA (12 protein-coding genes, 2 rRNAs and 22 tRNAs) revealed the phylogenetic position of Cathartidae ( Cathartes aura ) was more closer to Ciconiidae (storks) than Accipitridae. To investigate the divergence times of the CCRs in Falconiformes, detailed analyses of the noncoding regions (CR and CCR) were performed. We found the recently reported novel gene order in Falconiformes had multiple independent origins and hence cannot be used to infer phylogenetic lineages. Indeed, the molecular clock suggested the CCR in Falconidae emerged about 65.4 million years (Mya), while that in Pandionidae–Accipitridae clade emerged about 19.16 Mya. The intra-genomic homology between the noncoding regions was detected in Spilornis cheela , which supporting the duplication hypothesis. Furthermore, the structure of CCR should be featured by a region containing tandem repeats as two definitely separated clusters of tandem repeats were found. The findings presented here should be considered in future phylogenetic and evolutionary studies targeting the pseudo-control regions of all Falconiformes species.