SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Imaging tumor vessels as a marker for p53 mutation status in cancer

The p53 protein is mutated in over 50% of cancers. Because its expression often promotes tumor growth and is associated with resistance to treatment, there has been great interest in treating cancers based on p53 mutation status. However, the use of p53- targeted therapies requires knowing the mutation status. DNA sequencing is one approach, but requires invasive biopsies, and newer sequencing techniques still face technical hurdles. Non-invasive imaging techniques offer an alternative approach for detecting mutation status. Given that p53 regulates blood vessel growth, and that vessel imaging is used clinically to monitor response to cancer therapy, I hypothesize that tumor vessels could be used as an imaging marker to identify p53 mutation status. To test this hypothesis, I will measure relationships between p53 mutations and vessel structure/function using my expertise in 3D cell biology, vessel imaging, and image analysis and the unique expertise of the host lab in p53 biology, proteomics, and flow cytometry. The objectives of this interdisciplinary work are: 1) to screen the effect of p53 mutants on vessel structure in vitro; 2) to characterize the molecular response of endothelial cells to p53-targeted therapies; and 3) to image the structure and function of vessels in mutant p53 tumors in vivo. If a relationship is found between p53 mutation status and tumor vessel features, then it could lead to the development of the first imaging marker of p53 mutation status. This marker could help clinicians select p53-directed therapies to personalize therapy for each cancer patient. Apart from scientific impact, the proposed work will also expand my career prospects and scientific network in Europe. Under the mentorship of the host lab supervisor Prof. Sir David Lane, who discovered p53, I will receive focused training to strengthen and diversify the scientific and transferable skills I need to transition from postdoctoral scientist to junior group leader.
European nuclear experimental educational platform (eneep)

The aim and the overall objective of the project is to build European Nuclear Experimental Educational Platform (ENEEP) which will fulfill needs of European users in order to significantly enhance their experimental education and hands-on activities in nuclear curricula, particularly in the field of nuclear safety and radiation protection. 
ENEEP will be established as an open platform for any European university or European research institute that are actively involved in experimental nuclear education, training and competence building. The ENEEP founding members will be all five partners of this project, i.e. STU, CTU, TU Wien, JSI, and BME. All partners are heavily involved in experimental nuclear education, training and competence building. Four project partners, namely STU, CTU, TU Wien and BME, established in 2003 the Eugene Wigner course which put together three research nuclear reactors and offered experimental reactor courses for master students in nuclear engineering using these reactors. 
The main goal will be achieved through specific objectives of the project. Each specific objective will be achieved through the implementation of particular or multiple work packages and are strongly interconnected. As a result, the ENEEP will be established as well as its education and training capabilities will be demonstrated.
The project will contribute to the expected impacts set out in the work programme, under the relevant topic - NFRP-2018-7: Availability and use of research infrastructures for education, training and competence building. The proposed project will enable the establishment of the ENEEP platform, aimed at becoming the leading European platform offering experimental nuclear education and training activities. Based on the experience from the last years, we expect that the number of students and trainees during five years after the project end will reach up to 1300 persons.
Young Children's Response to Technological Components in Dramatic Activities Relying on Robot Projector Based Augmented Reality

본 연구의 목적은 증강현실과 로봇 기술을 결합한 동극 활동을 개발하고, 교육 현장에 적용하였을 때 유아가 증강현실과 로봇이라는 기술적인 요소에 어떻게 반응하는지를 살펴보고자 하는 것이었다. 연구의 목적을 위해 5세 학급의 유아 16명을 대상으로 증강현실과 로봇을 기반으로 한 동극 활동을 적용하고 유아의 반응을 다음과 같은 내용의 인터뷰를 통해 조사하였다; 1) 증강현실 기술에 대한 유아의 반응(이해도와 흥미도), 2) 로봇 기술에 대한 유아의 반응(이해도와 흥미도). 연구 결과, 유아들은 증강현실과 로봇 기술에 대해 잘 이해하고 있었으며, 흥미도도 비교적 높은 것으로 나타났다. 본 연구는 증강현실과 로봇이라는 새로운 테크놀로지를 유아들이 어떻게 이해하고 받아들이는지를 밝힘으로서 유치원 현장에서의 활용 가능성을 발견하였다는데 그 의의가 있다고 하겠다. The purpose of this study was to investigate young children's response to technological components in dramatic activities relying on robot projector based augmented reality. The participants of this study were 16 five-year-old children. Young children's response to the technological components was collected by interviews asking 1) the level of understanding and interest in robot technology and 2) the level of understanding and interest in augmented reality technology. The result of this study showed that most of children playing the role of actors as well as audiences were likely to understand and get interested in the robot and augmented realty technology. This study would support the feasibility of employing the robot projector based augmented reality contents to dramatic activities in early childhood settings.
FRACTURING A FORMATION WITH MORTAR SLURRY

A method to provide a plurality of fractures in a subterranean formation includes providing an essentially horizontal wellbore in the subterranean formation and providing a casing in the essentially horizontal wellbore. The method also includes providing communication between an inside of the casing and the subterranean formation at a plurality of locations along the length of the horizontal wellbore and providing a mortar slurry within the casing. The method further includes initiating a plurality of fractures from the plurality of locations and propagating the plurality of fractures by adding mortar slurry to the wellbore. A pressure inside the casing within the subterranean formation is above a fracture opening pressure while the plurality of fractures is propagating.
Turiviva+:Tourisme supérieur: Bien-être local et expériences Routes dans un écosystème insulaire

La?Turiviva+? met l’accent sur la durabilité, la participation du touriste senior à l’écosystème de l’île, les composantes de la biodiversité, de l’histoire et du patrimoine, les mémoires populaires et les traditions des 6 municipalités de S. Miguel, pour offrir des expériences positives de bien-être, à travers des itinéraires innovants. Comprend 3 études: 1. Bien-être du touriste senior. 2. Histoires de vie — souvenirs d’expériences des personnes âgées avec les lieux 3. Contenu innovant
METHOD FOR DISACIDIFYING PAPER PRODUCTS WITH PRINTINGS OR INSCRIPTIONS

The invention relates to a method and device for disacidifying paper products with printings or inscriptions (thereafter called "books"). According to said method, book pages to be treated are wide opened by means of an opening jet and the active material is injected between the pages of the wide opened book pages by means of a jet of active material. In order to reduce flow resistance between independent pages (4) of the book (3), suction is applied on the opposite side of the book. A bent slot-shaped nozzle (12) is also provided for producing a corresponding opening jet (11).
A smart, energy autonomous, universal and cost-effective dynamic passenger information system

PIXEL is a Polish B2B SME, a pioneer and market leader in the development and delivery of passenger information system
in the Transport Sector. We operate in an industry that is expected to growth to $20.34 Billion by 2019 at a CAGR of 26.5%.
We develop all our innovative products with the belief and values of freedom of mobility. Due to language barriers and the
fact that only 19% of Europeans are bilingual the Public Transport needs to be innovative and leverage advances in Smart
City and Intelligent Transport System technologies to attract more citizens and foreigners to use the Public Transport and
facilitate freedom of mobility. To solve this problem we have created E-APIS, a smart, energy-autonomous, universal and
cost-effective dynamic passenger information system that removes all communication barriers and radically improves
freedom-of-movement in public transport across the EU Member States. The innovation lies in the integration of advanced
displays and mobile communications that are able to provide real-time information in any chosen language and low-power
technologies that allow 24/7 365 days of autonomous power through renewable energy sources.

Our solution provides a high economic impact to Transport Operators since it removes energy bills and installation costs and
gives them a new revenue stream. These qualities will shorten payback periods and make the investment sustainable and
profitable. We foresee that E-APIS will add over €10 Million to our annual revenue by 2023, increase our annual profits by
25% and grow direct employment by 30% by 2021 (5 year ROI 14). Phase 1 of this innovative project is to carry out an
elaborate Feasibility Study and Business Plan to get E-APIS from TRL6 to TRL9 and commercialise it.
Chronic rhinosinusitis: an important overview.

Sinusitis, in general is a significant and increasing health problem resulting in a large financial burden in South Africa and to society in general. Increasing antibiotic resistance is a major problem with no new antibiotics on the immediate horizon and poor & inappropriate antibiotic usage amplifying this burden. Correct dosages of antibiotics are often not covered in formularies whereas inappropriate formulations of antibiotics and other inappropriate medications often are. The “Updated guideline for the management of upper respiratory tract infections in South Africa: 2008”, clearly defines the treatment of the various forms of sinusitis, with appropriate antibiotics, where required, and their dosages clearly laid out1. This guideline appears to be poorly applied in general. Inappropriate use of other non-antibiotic, especially over the counter treatments adds considerably to these issues especially costs2.

More important though is that accurate diagnosis is an absolute essential for treatment of the various forms of sinusitis. 

Rhinitis and sinusitis usually coexist and are concurrent in most; the correct terminology is now rhinosinusitis.3
Reliable aircraft electrical insulation system selection

In the last years, the need for high power density and efficiency has become a central concern in all industrial sectors. For this reason, the arrival on the market of new power devices based on wide bandgap (SiC and GaN) semiconductors, with extremely short switching times, has raised a relevant interest.
Aerospace industry is one of the main areas which can take advantage from these devices. According to the MEA concept, replacing the aircraft’s hydraulic/mechanical actuators with electrical drives yields an improvement in efficiency and power density, which means a reduction in weight, fuel consumption and noise/pollutants emission. However, some reliability issues may arise in this type of electric drives, as devices with higher voltage gradients have a negative impact on the performace of high voltage insulation systems.
As such, there is a need to assess if state-of-the-art insulation materials of machines and power electronic components are suitable for future applications using higher supply voltages and higher switching gradients. The proposed project comprehends the analysis and the experimental assessment of state-of-the-art insulation materials and systems used in aircraft applications.
The political economy of power relations

Political economists want to understand conflict, electoral competition, special interest politics, regimes and institutional choices, and in all these subfields the term power appears frequently: power of countries, power of ethnic groups, power of interest groups, power of parties, power of the bureaucracy.
Power is multidimensional and endogenous, and hence the standard theoretical and empirical analysis that takes a unified notion of power as an independent variable has led to wrong directions.
By acknowledging that power is multidimensional and endogenous, and thereby studying the endogenous interactions between the different types of power, we can further significantly the frontier of political economy.
In particular, I am going to show, theoretically and empirically, that all kinds of conflict, from civil war to interstate war and even class conflict, depend on the “mismatch” between the relative power of the key players on different dimensions, for example military and political power.
An important byproduct of the mismatch theory is for the interpretation of the history of conflict after 1950:
I claim that it is Bretton Woods that created the ground for a significant discontinuity, cutting down the incentives to interstate wars but increasing the incentives to start civil wars.
Finally, the general idea that the dynamics of one type of power can depend significantly on relative power in other spheres will be applied also to the relationship between political power and the power of bureaucracies.
The empirical part of the project will involve new measurements of power and will benefit from collection of data on political texts, policy platform texts, legal texts and economic strength of ethnic groups over time and cross-countries.
COUPLING COMPRISING A SHAFT INSERTED AT LEAST PARTIALLY INTO A HOLLOW SHAFT AND A RING PART SLIPPED ONTO THE HOLLOW SHAFT, AND PLANETARY GEAR

The invention relates to a coupling comprising a shaft inserted at least partially into a hollow shaft and a ring part slipped onto the hollow shaft, in particular a clamping ring, wherein the ring part is axially delimited by a collar formed on the shaft, in particular a radially protruding collar, and/or the ring part abuts a collar or the shaft collar, in particular a collar formed on the shaft, in particular a radially protruding collar, the hollow shaft having slits spaced apart from the collar, in particular axial slits, wherein the ring part comprises a chamfer, in particular on its inner face and/or at its annular opening and/or in particular in its axial end region facing the collar, such that the inner diameter of the ring part in the axial region covered by the chamfer is greater than the inner diameter in the axial region in which the ring part contacts the hollow shaft, an uneven number of groups of axial bores, in particular three, being produced in the ring part, the median points or midpoints of the groups determined in the peripheral direction being regularly spaced apart in the peripheral direction.
Capturing interactions in architectural patterns

Patterns of software architecture help in describing structural and functional properties of a system in terms of smaller components. The emphasis of this work is on capturing the aspects of pattern descriptions and the properties of inter-component interactions including non-deterministic behavior. Through these descriptions we, capture structural and behavioral specifications as well as properties against which the specifications are verified. The patterns covered in this paper are variants of Proxy, Chain, MVC, Acceptor-Connector, Publisher-Subscriber and Dinning Philosopher patterns. While the machines are CCS-based, the properties have been described in Modal μ-Calculus. The approach serves as a framework for precise architectural descriptions.
Bitter Freedom: Ireland In A Revolutionary World 1918-1923

A new history of the Irish Revolution, placing Ireland in the global disorder born of the terrible slaughter of total war, as well as a kaleidoscopic portrait of the human face of the conflict. Ireland was part of a civilisation in turmoil. A national revolution which captured worldwide attention from India to Argentina was itself profoundly shaped by international events, political, economic and cultural. In the era of Bolshevism and jazz, developments in Europe and America had a profound effect on Ireland, influencing the attitudes and expectations of combatants and civilians. The price of freedom was partition, a devastating civil war and the daunting challenge of establishing a new nation in an uncertain world
Transforming digital in-content advertising to deliver global scale

Today, digital advertising is dominated by big, US-driven companies like Google and Facebook, who provide the majority of the ads we see online. The old dominant concept has been to sell and show static banner ads in a fixed location, separated from Publisher digital content. The problem with this approach is that ads are placed where they are usually ignored and, being mostly poorly targeted, are not adding value to end users. The next generation concept in digital advertising will be in-content advertising, where advertising is turned into a service in order to enhance the end user experience. It means that advertisements are placed dynamically inside the actual content of the Publisher digital property and served in the right context for the right audience as identified by behavioral data. In-content advertising unites programmatic advertising technology with real-time bidding and performance based advertising. 

Kiosked launched its innovative in-content advertising platform in 2014, generating significant interest from publishers, advertisers and investors. Kiosked has grown over a 9 month period in a highly competitive marketplace to serve over 250 million people with more than 3 billion ads on a monthly basis. Growth continues, however, the current manual sales process has been identified as a limiting factor to growth; the next innovation is to enable a data driven automated online marketing and sales service. In this project, the Kiosked platform will be developed into a fully automated, end-to-end service, thereby allowing any digital publisher to onboard the service at any time. Data drives Programmatic advertising and effective advertising performance delivering enhanced end-user experience. This project enables Kiosked to efficiently connect Publishers’ audience with programmatic advertising buyers delivering greater data driven value and granting Kiosked the ability to scale globally into one of the world’s biggest players in digital advertising.
Chronic hypoxia decreases arterial and venous compliance in isolated perfused rat lungs: an effect that is reversed by exogenous <scp>l</scp>-arginine

Chronic hypoxia (CH)-induced pulmonary hypertension is characterized by vasoconstriction and vascular remodeling, leading to right ventricular dysfunction. Given the role of arterial compliance ( C a ) in right ventricular work, a decrease in C a would add to right ventricular work. Nitric oxide (NO) is a potent vasodilator made by NO synthases from l-arginine (l-Arg). However, little is known of the effect of l-Arg on vascular compliance ( C v ) in the lung. We hypothesized that exposure to CH would decrease C a and that this effect would be reversed by exogenous l-Arg. Sprague-Dawley rats were exposed to either normoxia or CH for 14 days; the lungs were then isolated and perfused. Vascular occlusions were performed and modeled using a three-compliance, two-resistor model. Pressure-flow curves were generated, and a distensible vessel model was used to estimate distensibility and a vascular resistance parameter ( R 0 ). Hypoxia resulted in the expected increase in arterial resistance ( R a ) as well as a decrease in both C a and C v . l-Arg had little effect on R a , C a , or C v in isolated lungs from normoxic animals. l-Arg decreased R a in lungs from CH rats and redistributed compliance to approximately that found in normoxic lungs. CH increased R 0 , and l-Arg reversed this increase in R 0 . l-Arg increased exhaled NO, and inhibition of l-Arg uptake attenuated the l-Arg-induced increase in exhaled NO. These data demonstrate that the CH-induced decrease in C a was reversed by l-Arg, suggesting that l-Arg may improve CH-induced right ventricular dysfunction.
Application for broadband availability mapping (a-bam)

The A-BAM (Application for Broadband Availability Mapping) project will develop a feasibility study for a mobile application that aggregates the needs of all the key stakeholders in the development of broadband connectivity, in one single place, throughout Europe: Local/Regional/National Administrations, End-Users and ISPs (Internet Service Providers). 

It will assist users such as households or businesses to ascertain the broadband options and services that are available in any particular area, allowing where applicable to select other ISPs offering higher speed broadband services at their location through a Europe-wide switching service. This will benefit ISPs by providing an additional marketing channel to help them engage with, and attract, new customers. Additionally, it will enable households and SMEs to identify whether any government or privately funded broadband promotion schemes are already available and what these are, or identify any infrastructure schemes that are planned in the area. The application will aggregate and provide this data for local and regional governments in order to facilitate the tailoring as well as adoption of these schemes aimed at supporting Europe to meet the objectives set forth in the EC Digital Agenda: universal availability of Broadband speeds of at least 30 Mb/s throughout Europe, with 50% having speeds above 100 Mb/s.
The Emergence of Family-specific Support Constructs: Cross-level Effects of Family-supportive Supervision and Family-Supportive Organization Perceptions on Individual Outcomes

Implicit to the definitions of both family-supportive supervision (FSS) and family-supportive organization perceptions (FSOP) is the argument that these constructs may manifest at a higher (e.g. group or organizational) level. In line with these conceptualizations, grounded in tenants of conservation of resources theory, we argue that FSS and FSOP, as universal resources, are emergent constructs at the organizational level, which have cross-level effects on work-family conflict and turnover intentions. To test our theoretically derived hypotheses, a multilevel model was examined in which FSS and FSOP at the unit level predict individual work-to-family conflict, which in turn predicts turnover intentions. Our hypothesized model was generally supported. Collectively, our results point to FSOP serving as an explanatory mechanism of the effects that mutual perceptions of FSS have on individual experiences of work-to-family conflict and turnover intentions. Lagged (i.e. overtime) cross-level effects of the model were also confirmed in supplementary analyses. Our results extend our theoretical understanding of FSS and FSOP by demonstrating the utility of conceptualizing them as universal resources, opening up a variety of avenues for future research. Copyright © 2015 John Wiley & Sons, Ltd.
Picture the past from the present

Mobile multimedia computing and services can enhance the ways people live, work, play and travel. In this paper, we present an application of content-based image retrieval (CBIR) technology to retrieving historical images for enhancing the experience of tourists visiting historical attractions. We adapt a video object retrieval approach and use images taken with modern cameras or smartphones as query examples to find other images of the same place from an online historical photograph collection containing over 80,000 images recording the history of the local communities of Derbyshire and Nottinghamshire in England over the last hundred years. We present preliminary results to show that advanced video object retrieval technology can be potentially very useful for delivering mobile multimedia services to enable visitors to explore the visual history of attractions.