SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
The geology of the Amstel river in Amsterdam (Netherlands): Man versus nature

Abstract The Amstel river is located in the peat-covered coastal plain of the Netherlands and gives Amsterdam its name (Amstel dam). It is a small secondary branch of the repeatedly bifurcating Rhine delta system. Historically, the Amstel debouched into the peat-fringed former Oer-IJ estuary, which was connected to the North Sea, but after the closure of this inlet the estuary was transformed into an inland sea (IJ) due to erosion of the adjacent peat. The Amstel river was active between 3000 BP and 1122 AD after which time the supply water from the Rhine was stopped due to the construction of a dam far upstream near Wijk bij Duurstede. On the basis of borehole data from various sources, four cross-sections were constructed in the Amstel branch to study the unknown lithology and lithostratigraphy of the Amstel sediments in the Amsterdam area. The deposits show the Amstel was a low-energy river which carried mainly clay. The cross-sections reveal that the Amstel in its downstream part was flanked by two lithologically identical layers of overbank clay, intercalated by a peat layer. The lowermost overbank clay was deposited from 3000 BP to about 1000 AD. The intercalated peat layer is estimated to have developed between the 11th and 12th centuries AD, indicating a decreased sediment supply in the Amstel, and rise of water level in the downstream river caused by Zuiderzee influences such as storms and tide. The uppermost overbank clay was deposited during major storm surges such as those documented in 1164 and 1170 AD, and was derived from the brackish Zuiderzee; it has been traced upstream along the Amstel for over 10 km. Near the mouth of the Amstel channel in the Oer-IJ estuary its bottom has been scoured by estuarine processes to a lower level. On the basis of archaeological and geological data it is argued that the Amstel channel of medieval Amsterdam had a water depth of about 6 m before the construction of a dam in the 13th century. Soil scientists, historical geographers and historians have argued that the Amstel once consisted of two separate rivers: a northern Oer-IJ connected channel draining from the Amsterdam Stopera to the north, and a southern peat draining channel draining from the Amsterdam-Watergraafsmeer to the south. The relatively straight stretch of the present-day Amstel now positioned within the urban area has been hypothesised to be man-made between the 11th and 13th centuries AD. In this paper, on the basis of geological arguments such as channel depths, overbank clays, peat composition and other characteristics, it is concluded that the Amstel had a natural channel in the Amsterdam area.
Job evaluation made easy for european smes. unique innovative solution to perform digital job evaluation, compensation analytics and management in an easy, transparent and cost-effective way.

Problem: In Europe, only 49% of the organisations in the private sector use formal Job Evaluation schemes, with SMEs less than 3%. Lack of effective Job Evaluation procedures often results in unstructured wage payment practices and missed opportunities for requirements-based career and skill development of employees and costly litigations.

Value proposition: 222.000 EU SMEs with 50-250 employees could benefit from gradar® platform. At only 5% take-up of the new SaaS by all concerned SMEs this could lead to around €1.1 billion savings and over 2000 new jobs across the SME sector.

Solution: gradar® is a highly innovative, web-based single resource for SMEs for managing every aspect of the job evaluation process in an easy-to-use and cost-efficient way. Now, we are the only company worldwide that offers job evaluation together with a default model of relevant job specific competencies as a Software as a Service (SaaS) based product. nThe company’s algorithms are proactively audited for demographic (gender) bias.

Product and technology: We are on the market with a first version of the product and already demonstrating over €90,000 (15-21% of total costs) per year savings from more efficient people utilisation and payment practices. This project will improve functionality and usability by enhancing the Competency module and implementing Compensation Analytics, Benchmarking and Management modules

Competition: HR consulting firms like AON/Hewitt, Deloitte, KornFerryHay, hkp group, Kienbaum, Lurse, Mercer, PWC, Willis Towers Watson and a variety of micro players.

Go-to-market: Target customers SMEs with 50-250 headcount from core markets Germany, Netherlands, Belgium, Italy, UK and Spain. Implementation partnership agreements in target areas to be finalized mid-2020. We have introduced a transparent, four-tier license cost model that is unique on the market.

Key milestones: Anticipated turnover of €30.8M by 2025 and 43 new employees five years after commercialization.
PHARMACY PRINTER SYSTEM AND METHOD

A computer network system and method for printing accompanying information and prescription labels in pharmacies, comprises: a central CS; a PMS; a data transmission network through which said PMS and said central CS can communicate; wherein said PMS includes an I/O terminal, a scanner, and a first printer; wherein said PMS includes a PMS SO and a Catalina SO; said PMS SO is configured to receive and store prescription information for a prescription, and to associate a prescription identification with said prescription; said Catalina SO is configure to select accompanying information for said prescription, to format and save said accompanying information in an accompanying information print file; and said PMS is configured to print a prescription label for said prescription and said accompanying information print file.
MIMO FESTIVAL 2017

The Mimo Festival 2017 will take place on 21 and 23 July 2017 in Amarante.This festival also ensures the added value of an international musical event with enormous visibility and attractive for the presence of several renowned national and international artists. Its media projection at the level of broadcasts and television reports raises the number of audiences reached to very high levels.
APPARATUS AND METHOD FOR TREATING A WORKPIECE WITH IONIZING GAS PLASMA

An apparatus to treat a workpiece with an ionizing gas plasma at about atmospheric pressure. The apparatus may include an outer electrode with at least one opening that also serves to hold the workpiece. An inner electrode may fit at least partially within the workpiece so as to create a plasma discharge zone between the inner electrode and an inner surface of the workpiece. A gas supply manifold may be included that directs a gas into the plasma discharge zone. A power supply may be used to generate an ionizing gas plasma in the plasma discharge zone. In one embodiment, there is a coating on an inner surface of the workpiece.
From bottle to stone. recyclable engineered stone for countertops.

SUSTONABLE is a revolutionary thin and ultra-lightweight building material developed and patented by INNSTECH, with the physical look and feel of engineered (quartz) stone. The product has a high scratch and impact resistance. The end product weighs 1/3 of current engineered stone while using only 20% of the raw materials.
In recent 30 years composite stone has been replacing natural stone in the kitchen. Artificial stone is a factory-made alternative with all the beauty of the natural material and the added benefits of resistance to staining, consistent colour, ease of handling and cutting. It is a fast-growing segment with 400M m2 countertops sold and will continue to gain share from less desirable materials such as HP Laminate worktops, which still represent 50% of the market as the cheapest option.
We at INNSTECH have pioneered the way to use recycled PET from plastic bottles and create a thin composite stone-like material that is recyclable with a very efficient process, and still having the desired look, feel and properties of current composite stone.  Moreover, we can drastically reduce SUSTONABLE price than comparable materials in the market -up to 50% cheaper than top vendor engineered stone, e.g. Silestone with sales €548M/yr.
Our vision is to deliver the next generation stone surface materials ready for the new sustainable circular economy, while positioning SUSTONABLE in the low-cost segment of the market offering the high-quality functional properties of competitors.
Having already successfully run our process in a pilot plant, SUSTONABLE has produced approximately 450 slabs of 250x80cm. The business strategy is first to prove the technology in the kitchen market by building and operating a medium scale plant with a capacity of 400,000 m2/year, reaching €12.6 million revenues in 2024.
The kitchen countertop leader in NL, Dekker (3500 countertops per week), has signed up as a co-investor in the project with the intention to sell and install SUSTONAB
Modelo de proceso de cuidado nutricional: consenso para Latinoamérica

Introducción: los modelos de cuidado nutricional son procesos estandarizados y sistematizados, cuyo objetivo es brindar consistencia y vinculación de la información, lo cual genera un impacto positivo en términos de calidad, servicio y costos. El objetivo del consenso de expertos fue proponer un modelo de cuidado nutricional para Latinoamérica, teniendo en cuenta el principio No. 2 de la Declaración Internacional de Cartagena. Método: se desarrolló un cuestionario, el cual fue sometido a la opinión de expertos siguiendo la metodología Delphi. El cuestionario inicialmente contó con 16 preguntas que evaluaban los siguientes temas: ¿cuáles son las etapas y herramientas del modelo? ¿Qué enfoque debe tener? ¿Sobre qué pilares fundamentar el modelo? Se consideró consenso cuando los ítems del cuestionario lograron un puntaje ≥ 70 % en la escala de Likert 4 (de acuerdo) y 5 (totalmente de acuerdo). Resultados: se realizaron tres rondas de consulta a expertos, donde se definió un modelo consistente en cinco pasos (que inició con el tamizaje del riesgo de desnutrición y terminó con los cuidados domiciliarios), los cuales se fundamentan en cinco pilares: educación, políticas públicas, fundamentos éticos, economía de la nutrición clínica y enfoque multidisciplinar/multisectorial. Se propusieron y analizaron indicadores de calidad de cada uno de los cinco pasos. Conclusión: el modelo de cuidado nutricional para Latinoamérica se basa en cinco pasos y cinco pilares. Este modelo se debe considerar como una herramienta y estrategia didáctica, que facilite la implementación y enseñanza del cuidado nutricional en el contexto latinoamericano en el ámbito clínico en todo nivel de atención.
Analysis of Baseball-to-Helmet Impacts in Major League Baseball

Background: In Major League Baseball (MLB), helmet hit-by-pitch (H-HBP) incidents are a leading cause of concussion. However, not all H-HBPs result in diagnosed concussion. Purpose: This study was designed to (1) quantify batter concussion risk as a function of H-HBP pitch velocity, time duration batter spent on the ground post–H-HBP, first responder assessment time duration, and number of days missed post–H-HBP and (2) estimate H-HBP impact locations on the helmet with respect to current National Operating Committee on Standards for Athletic Equipment (NOCSAE) helmet test standards and correlate impact locations with concussion diagnosis. Study Design: Case-control study; Level of evidence, 3. Methods: A retrospective case-control study of 18 MLB players with H-HBP incidents in the 2009 and 2010 seasons was undertaken. A database was compiled via quantitative and qualitative analysis using video coverage obtained from MLB. Quantitative factors included batter concussion diagnosis, pitch velocity, number of days missed post–H-HBP, time duration batter spent on the ground post–H-HBP, and first responder assessment time duration. The H-HBP impact location was among several qualitative factors developed via video analysis of each H-HBP from 4 raters. Results: In our study, 9 players (50%) were diagnosed with concussion. Concussion diagnoses were more frequent for posterior versus anterior impacts. The majority of H-HBP impact locations were different from those in the current NOCSAE standard tests. First responders took an average of approximately 65 seconds (time to reach batter plus assessment time) to decide on batter removal/return to play. The 25% logistic regression concussion risk threshold for pitch velocity and days missed was 86.2 mph and 1.3 days, respectively. The number of days missed after H-HBP showed a significant correlation ( P = .02) among concussed and nonconcussed batters. Conclusion: In professional baseball H-HBP incidents, first responders should (1) be aware of pitch velocity in excess of 86 mph and (2) be provided ample time when assessing batters’ removal/return to play. Clinical Relevance: First responders should not rely solely on visual indicators such as batter reaction, holding head, or amount of time spent on the ground after H-HBP when assessing batters for concussion. Batting helmets in the MLB should maximize protection and mitigate impact dosage for H-HBP impact locations and velocity in addition to NOCSAE standard test locations and velocities.
Next generation of advanced integrated assessment modelling to support climate policy making

NAVIGATE aims to develop the Next generation of AdVanced InteGrated Assessment modelling to support climaTE policy making. It will critically improve the capability of Integrated Assessment Models (IAMs) to inform the design and evaluation of climate policies by targeting major advancements in two areas: describing transformative change in the economy, in technology and in consumer goods and services, and describing distributional impacts of climate change and climate policy. By tackling existing weaknesses and lack of capabilities of the current generation of IAMs, NAVIGATE will provide new insight into how long-term climate goals can translate into short-term policy action, and how countries and sectors can work in concert to implement the Paris Agreement. NAVIGATE is bringing together leading institutions in the field of integrated assessment modelling with leading domain experts. They will provide a broad and diverse collection of state-of-the-art tools ranging from domain specific models and data to an extensive set of flagship IAMs to foster a successful implementation of the project. NAVIGATE will engage in a concerted effort to increase the usability, transparency, legitimacy and hence uptake of IAM results. At the center of this will be a stakeholder dialogue to elicit user needs and engage in co-production of knowledge about IAMs and their uses. This will be accompanied by the development of methodologies to better assess the robustness of  IAM results, by extended model documentation and new communication tools, and by capacity building efforts to lower the entrance barrier to IAM activities for other research teams, including research teams in less-developed countries. The NAVIGATE partners have long-standing expertise in national, EU and international climate policy advice and will actively promote uptake of project results by policy makers and international assessments.
Sostegno alle piccole imprese con un fatturato superiore a 500 000 BGN per superare l'impatto economico della pandemia di COVID-19

Sostegno alle piccole imprese con un fatturato superiore a 500 000 BGN per superare l'impatto economico della pandemia di COVID-19
Bacteria-Phage-Antibiotic interactions in variable environments: a community ecology perspective

There is increasing awareness that diversity in microbial communities likely plays a critical role in multiple biological processes, from regulating human health to sustaining ecosystem services. Along with advances in molecular technologies, this realisation has seen a rapid growth in efforts to catalogue microbial life, and yet we still have a surprisingly poor understanding of the mechanisms maintaining microbial diversity. With up to 1,000 different species in the human gut alone, classical ecological explanations for diversity maintenance appear unlikely to hold. A resolution to this coexistence paradox may lie in the dynamic nature of microbial environments. The goal of this project is to investigate whether recent theoretical advances in understanding coexistence in non-equilibrium systems can provide insights into microbial diversity in the presence of viral parasites and antimicrobial agents that naturally vary in concentration in space and time. To this end, I will conduct a series of innovative experiments on multi-strain communities of pathogenic and non-pathogenic Escherichia coli under spatial and temporal variability in nutrient resources, phages and antibiotics. The project is unique in community ecology in leveraging high-throughput methods in a model microbial system of significant human interest; and in its focus on the interaction between non-linear growth functions and environmental variability as a critical determinant of community dynamics. The results will i) enhance our understanding of the role of viral parasitism in regulating diversity; ii) provide insight into emerging theory on the operation of coexistence mechanisms at different spatial and temporal scales; and iii) inform evolutionary and epidemiological research into the combined effect of antibiotics and phages on bacterial performance.
RM-04 * RETINOBLASTOMA BINDING PROTEIN 4 (RBBP4) MODULATES TEMOZOLOMIDE RESPONSE THROUGH REGULATION OF MGMT EXPRESSION IN GLIOBLASTOMA

Through shRNA library screen we identified RBBP4 as a modulator of TMZ response in glioblastoma (GBM). Consequently, we investigated the mechanisms whereby RBBP4 modulates TMZ response using shRNA to silence this gene in MGMT-expressing T98G and U138 GBM cells. The cytotoxicity was evaluated using fluorescence-based CYQUANT proliferation assay. A total of 4 shRNA constructs significantly suppressed RBBP4 in both T98G and U138. Cells expressing non-specific targeting shRNA (NT-shRNA) were used as control. RBBP4 knockdown significantly sensitized TMZ both in T98G and U138 cells; the relative fluorescence for the TMZ-treated (100 µM) control T98NT-shRNA cells was 1.17 ± 0.15, whereas for T98RBBP4-shRNA clones were 0.54 ± 0.02, 0.29 ± 0.03, 0.36 ± 0.05, and 0.34 ± 0.03, respectively (p < 0.001). Similar sensitization was observed in U138 cells; relative fluorescence for the TMZ-treated (300 µM) control U138NT-shRNA cells was 0.70 ± 0.05 and for U138RBBP4-shRNA clones were 0.42 ± 0.06, 0.27 ± 0.01, 0.28 ± 0.02, and 0.30 ± 0.01, respectively (p < 0.001). Interestingly, knockdown of RBBP4 in T98G was accompanied with a synthetic lethality to PARP inhibition and increased response to TMZ-induced DNA damage, as evidenced by increased phosphorylation of KAP1, CHK1 and CHK2. Moreover, phosphorylation of H2AX in response to TMZ treatment was significantly higher in T98RBBP4-shRNA clones. Consistent with deficient homologous recombination (HR), T98RBBP4-shRNA clones significantly expressed less RAD51 compared with the control T98NT-shRNA cells. Even more interesting, RBBP4 knockdown silenced MGMT expression in both T98G and U138, which was accompanied by decreased recruitment of acetylated H3K9 coupled with increased recruitment of tri-methylated H3K9. Moreover, RBBP4 knockdown was coupled with loss of p300 recruitment to bind MGMT promoter region. Collectively, these findings suggest that RBBP4 modulates TMZ response in GBM cells through epigenetic regulation of MGMT, and perhaps through RAD51-mediated HR repair of DNA damage in selected GBM cells.
European cities joining forces to improve city resilience

Cities are where the majority of the population lives, where innovation takes place and where the bulk of economic value is created. The future is hopeful and economists applaud the agglomerative effects of the city: proximity, diversity and density are considered keys to economic success.However, these are the same qualities that make cities vulnerable to the impacts of shocks and chronic stresses. In cities where stresses accumulate or sudden shocks occur, the result can be social breakdown, physical collapse or economic deprivation. In this reality, cities are not the solution but epicentres of the problem.In order for cities to live up to expectations, cities need to be able to continue to function no matter what stresses or shocks the people living and working in cities encounter. In other words: cities need to be resilient. The policy challenge facing our cities therefore is to increase our city’s resilience in order for its inhabitants to survive and thrive and for the city to successfully deliver on its potential for progress and in this way to contribute to transforming Europe into a smart, sustainable and inclusive society.We argue that it is the task of every city to lead the way in preparing their city to reorganize, adapt and regenerate urban structures and processes in the light of this resilience challenge without compromising the welfare and well-being of the citizens and the quality of social, ecological and economic services provided to them.
Robust recycling technology that separates different plastic types from a mix of plastic waste to produce a plastic material directly marketable to manufacturers

Plastic is today the 3rd material produced and global production has skyrocketed: from 1.5Mt in 1950 to 322Mt in 2015. But only 5% of worldwide produced plastic is today recycled, being one of the least recycled material. Plastic wastes that are not recycled are called Ultimate scrap residues and come mostly from End-of-life vehicles (ELV) and Waste Electrical and Electronic Equipment (WEEE). Today, companies producing Ultimate scrap residue have two options to discharge this waste: 1) Landfill disposal where they must pay a considerable fee (120€/t in 2015) with a strong environmental impact but this practice is expected to be soon banned in Europe; 2) selling and sending the wastes to Asia (mostly in China) at a price of 250€/ton but with the requirement of investing in expensive pre-treatment systems and with also negative environmental impact. Our TRIBOSORT technology is a unique solution that allows to 1) recycle all ultimate scrap residues from ELV and WEEE, 2) separate its valuable plastic components with a purity of 95% minimum, 3) provide an industrial scale solution with a production capacity of 1.5t/h, 4) produce a final recycled plastic material directly marketable to manufacturers, 5) provide a Recycle certificate along with our final products. APR2 is an experienced SME with 2.6M€ turnover and over 15 years in the plastic recycling market collecting, sorting and dismantling WEEE (over 5Kt treated every year) thanks to our 5,000m2 of exploitation area, 5 dismantling workshops, and 15 approved provider partners to recycle their wastes with recycling rate between 85 and 90%. APR2 has been awarded of many renown prices for its constant investment in R&D (10% annual du CA). Our first TRIBOSORT prototype design obtained a worldwide PCT Patent (WO 2010/109096 A1) and has been today delivered in 7 countries and pending in 2 further countries. We are certified “Adapted Company” (> of 80% handicapped persons employed), ISO 9001, 14001 and 50001.
Reproduction of period contoured wooden door - uses false panelling to increase apparent thickness of door

The reproduction of a period contoured wooden door has false panels that increase the apparent thickness of the door. The exterior and interior door panels (4) are fixed to the frame (2) which runs around all edges of the door and carries on its inside the central panel (1). The exterior panels are cut away to the required shape exposing the central panel and mouldings (7) close the exposed gap by fixing to the wedges (3) although the mouldings can be shaped so that they act as wedges as well as mouldings.