SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Preparation of enzyme linked immunosorbent assay kit for milk cow progesterone.

In order to investigate the change in progesterone level of cow to provide reference on heat and gestation period identification,and ovary disease diagnosis,the enzyme linked immunosorbent assay kit(ELISA) for cow progesterone was prepared based on primary mechanism of ELISA.The results showed that applying progesterone bovine serum albumin(P4-BSA) cross-linking polymer could solve the problem of enveloping antigen on ELISA plate,and antigen was easy to be conserved.It was found that high titer antibody could be obtained by applying progesterone-ovalbumin(P4-OVA) cross-linking polymer to immunize the rabit and it could block 1 ng/mL progesterone.The 2000 and 500 dilution times for P4-BSA and serum were found to be the optimal concentration of kit by ELISA chessboard method.The cow dung was used for detecting sample with kit,and the change in progesterone level of dung could provide reference on heat and gestation period identification,and diagnosis of reproduction barrier disease.
Rolling out osnma for the secure synchronization of telecom networks.

The study of critical dependancies upon GNSS-derived time and position identifies telecomunications, emergency services, energy, finance, food and transport as the sectors where GNSS plays a key role. GNSS is used as a timing source for the synchronization of various types of network and has been recently dened as the backbone of the connected world and also the invisible utility. Some of these networks are classied as critical infrastructures and, together with other service infrastructures, pose security-related requirements on top of timing accuracy requirements. 
ROOT (Rolling Out OSNMA for the secure synchronization of Telecom networks) project will assess the benefits introduced by the Galileo OSNMA signal in the specific context of telecommunication network synchronization applications. It will estimate the increased resiliance brough by OSNMA to GNSS-based timing sources. ROOT will consider the requirements, such as accuracy, tollerance to timing outages, etc., posed by the 5G playground to guarantee the expected perfomance. ROOT will follow an experimental approach to demonstrate and measure the increased level of robusteness provided by new multi-frequency, OSNMA-ready Galileo receivers, when they slave multiple timing sources across the network. This will be combined to secure network synchronization distribution by means of Precision Time Protocol and its White Rabbit flavour; specific network-related Key Performance Indicators will be measured. ROOT will foster the adoption of Galileo signals featuring authentication mechanisms in terrestrial infrastructures dependant upon satellite-derived time. 
ROOT partners cover the whole value chain for critical infrastructures: from research to manufacturers of GNSS and timing components, from networks operators to experts in market strategies, the partners complement each other in terms of knowledge and competences. They collectively constitute a consortium capable of fulfilling the project objectives.
APPARATUS FOR IMPROVED SUBAQUEOUS STABILITY

A locomotive element to be incorporated in an underwater device propelled on a supporting surface along a predetermined axis of motion. The locomotive element comprises at least one resilient surface that can be rolled on the supporting surface. The resilient surface has a plurality of flow-through passages substantially perpendicular to the axis of motion.
From making form to finding form: A new method of building form design

Traditional building form design methods have a clear and static target, but this article would discuss that nowadays the method of building form design changes from Making Form to Finding Form. Finding Form is a new method that architects do not have a clearer target, but there is a logical chain that contact with a variety of architectural elements of quantization. So this method can deal with very complicated architectural problem. And this paper also argues that Digital Technology is a key tool that supports the method of Finding Form. Because there are two advantages of digital tools: first, it can express architectural problem dynamically; Second, it can contact Form and Information closely.
4I-Traction – innovation, investment, infrastructure and sector integration: transformative policies for a climate-neutral european union

To achieve climate neutrality by 2050, EU policy will have to be reoriented. It needs work simultaneously towards climate neutrality across the economy rapidly enough to achieve the Paris Agreement’s goals, while delivering on a broad range of issues,  from competitiveness and productivity to employment and health. The concept of the European Green Deal captures this overarching narrative. However, to mobilise the creative, financial and political resources to achieve the required degree of technological, economic and behavioural change, the EU also needs a governance framework that facilitates  cross-sectoral policy integration and allows citizens, public and private stakeholders to participate in the process and to own the results. 
4I-TRACTION analyses what transformative climate policy could look like for the EU. Based on a stocktake of existing climate policies and their performance, it will spell out a number of policy avenues and an overarching governance framework, to describe how the current mix of EU climate and energy policies needs to evolve in the 2020s to set course for climate neutrality by 2050. The analysis will be structured around four cross-cutting core challenges, the “4 I’s”: 1) fostering breakthrough Innovation, 2) shifting Investment and finance, 3) rolling out the Infrastructure for a climate-neutral and resilient economy, and 4) Integrating solutions across sectors. This structure reflects that a systemic transformation will need to evolve beyond sectoral policy approaches. Incorporating scientific insights and policies from outside the EU as well as examining how the EU’s efforts interact with those of other key countries, the analysis will also include the global context. The analysis will be thoroughly grounded in science, but also aligned with the EU's dynamic political environment. To receive input, provide feedback and validate conclusions, the project will closely engage with a broad set of stakeholders throughout its lifespan.
Post-traumatic apexogenesis of immature non-vital permanent incisors.

Injury to an immature permanent tooth may result in cessation of dentin deposition and root maturation leaving an open root apex and thin dentinal walls that are prone to fracture. Endodontic treatment is often complicated and protracted with an uncertain prognosis frequently resulting in pre-mature tooth loss. There are several advantages of promoting apexogenesis in immature teeth with open apices. It encourages a longer and thicker root to develop thus decreasing the propensity of long term root fracture. This case report highlights the role of Hertwig root sheath and dental papilla in continued root formation of immature permanent tooth, even diagnosed with necrotic pulp.
PATCH AND PATCH PREPARATION

The invention provides a patch and a patch preparation having an adhesive layer with a high adhesive force, wherein the hydrophobic adhesive layer does not bloom even when an organic fluid component having high polarity is contained therein. The patch contains a support and an adhesive layer on at least one surface of the support, wherein the adhesive layer contains a synthetic rubber having a viscosity average molecular weight of 500,000-1,600,000, an organic fluid component having high polarity, a tackifier, and magnesium aluminometasilicate. In the patch preparation, the above-mentioned adhesive layer further contains a drug.
Inter-conveyed postal matter gap correction apparatus

An inter-conveyed postal matter gap correction apparatus includes a postal matter supply means, a detecting means (45) for detecting the thickness or weight of the postal matter supplied from the postal matter supply means, a gap measuring sensor (47) for measuring a gap between the postal matter supplied from the postal matter supply means, a variable speed driving means (42) arranged on the downstream side of the detecting means and the gap measuring sensor for driving the postal matter supplied from the postal matter supply means at various speeds, a memory for storing a correction value for driving the postal matter at various speeds by the variable speed driving means on the basis of the thickness or weight of the postal matter detected by the detecting means, a preceding gap which is a gap between the present postal matter to be corrected which is measured by the gap measuring sensor (47) and the just prior preceding postal matter, and a succeeding gap which is a gap between the present postal matter to be corrected and the just after succeeding postal matter, and a setting means for setting a drive speed of the variable speed driving means (42) using the correction value stored in the memory.
Integrated novel strategies for reducing the use and impact of pesticides, towards sustainable mediterranean vineyards and olive groves

The DIRECTIVE 2009/128/EC ON THE SUSTAINABLE USE OF PESTICIDES gives directions for attaining the sustainable use of pesticides in the EU. The objective is to minimize risks and impacts for the environment and human health by promoting alternative strategies. Integrated Pest Management (IPM) is one of the cornerstones of the Directive. NOVATERRA aims to reduce the use and negative impacts of CONTENTIOUS PLANT PROTECTION PRODUCTS (PPP) for integrated pest, disease and weed management in the two main Mediterranean crops in Europe: grapevines and olives. NOVATERRA will develop a pool of novel, integrated and sustainable strategies, technically and economically viable, resulting from three different approaches: a) To develop novel combinations of ALTERNATIVE, non-synthetic PRODUCTS and biological control techniques for plant protection, b) To optimize the application and dosage of PPP through SMART FARMING technologies and c) To mitigate the appearance of pest and diseases through the use of new SOIL MANAGEMENT strategies. Those approaches will be evaluated and validated in a combination of integrated solutions for updating and improving IPM strategies. Indicators for measuring the impact of crop management and protection on human health, air, water, soil, biodiversity, energy will be implemented. Further analyses will be done in terms of economic cost-benefit for farmers to adopt the different techniques and farmers and consumers’ willingness to pay. The consortium composition will guarantee a multi-actor approach with contributions coming from research institutions, growers, technological SMEs, auxiliary industry and relevant associations. Finally, the Exploitation Plan together with the Communication and Dissemination Plan will ensure the outreach of results among the stakeholders in the European farming sector. NOVATERRA outputs will also be key for further discussion with policymakers in terms of EU plant health policies and risk assessment around PPPs usage.
Bank Income Smoothing and Loan Loss Provisioning Practices in Africa

The primary objective of the thesis is to investigate whether African banks use loans loss provisions estimates to smooth reported earnings, and to determine the factors that influence the extent of earnings smoothing among African banks. Earnings smoothing via loan loss provision has been examined in several regions, but the case of Africa remain unexplored in the literature. In the thesis, earnings smoothing is viewed as an earnings management practice while loan loss provisions estimate is considered to be the tool used by African banks to smooth reported earnings.
Using African bank data obtained from Bankscope database, I test the earnings smoothing hypothesis for 370 African banks during the 2002 to 2014 period using the specific-accrual approach. The specific-accrual approach estimates a specific discretionary accrual as a function of its non-discretionary determinants and other factors that influence the manipulation of the specific accrual. The model specification expresses discretionary loan loss provisions as a function of earnings before provisions and tax, its non-discretionary determinants and other factors that influence the decision regarding the level of bank provisions for each period. The findings indicate that African banks manipulate loan loss provisions estimates to smooth reported earnings and this behaviour is influenced by bank differences, accounting disclosure differences and institutional differences across African countries.
The primary contribution to knowledge of the thesis is its extension of our understanding of the role of discretionary accruals in the bank financial reporting, focusing on African banks - a context that has not been extensively examined in the literature. Also, the thesis extends the bank earnings smoothing debate to the African context and the findings of this study are useful to bank regulators in Africa in their evaluation of whether bank loan loss provisions solely reflect credit risk considerations or whether bank loan loss provisions estimates reflect opportunistic considerations of African bank managers. Finally, the findings are useful to local accounting standard setters in the region in their evaluation of several accounting numbers that bank managers might use to manipulate reported earnings.
Phase transitions in a system of long rods on two-dimensional lattices by means of information theory

The orientational phase transitions that occur in the deposition of longitudinal polymers of length k (in terms of lattice units) are characterized by information theory techniques. We calculate the absolute value of an order parameter δ, which weights the relative orientations of the deposited rods, which varies between 0.0 (random orientation) and 1.0 (fully oriented in either of the two equivalent directions in an L×L square lattice). A Monte Carlo (MC) algorithm is implemented to induce a dynamics allowing for accommodation of the rods for any given density or coverage θ (ratio of the occupied sites over all the sites in the lattice). The files storing δ(t) (with time t measured in MC steps) are then treated by data recognizer wlzip based on data compressor techniques yielding the information content measured by a parameter η(θ). This allows us to recognize two maxima separated by a well-defined minimum for η(θ) provided k≥7. The first maximum is associated with an isotropic-nematic (I-N) phase transition occurring at intermediate density, while the second maximum is associated with some kind of nematic-isotropic transition at high coverage. In the cases of k<7, the curves for η(θ) are almost constant, presenting a very broad maximum which can hardly be associated with a phase transition. The study varies L and k, allowing for a basic scaling of the found critical densities towards the thermodynamic limit. These calculations confirm the tendency obtained by different methods in the case of the intermediate-density I-N phase transition, while this tendency is established here in the case of the high-density phase transition.
Machine learning software to design personalized neoantigen vaccines tailored to specific vaccine delivery systems

Cancer remains a leading cause of disease and death worldwide. An estimated 14m new cancer cases were diagnosed in 2012 and 22m are predicted by 2023. Immunotherapy and particularly personalized neoantigen-based vaccines represent an exciting new weapon in the war against cancer, as they are specific to the tumor and potentially safer and more effective than other types of treatment. However, the design of neoantigen-based cancer vaccines is currently hampered by an inability to reliably select immunogenic neoantigens using the existing technologies.
OncoImmunity proposes to develop disruptive software - MEDIVAC - for the rapid and intelligent design of neoantigen-based personalized cancer vaccines, tailored to specific vaccine deliver systems (VDS). The software will leverage a machine-learning framework being developed at OncoImmunity that addresses key prediction gaps in the field of neoantigen discovery. Preliminary testing of MEDIVAC´s prediction engine reveals that it can identify immunogenic neoantigens with an unprecedented level of accuracy, and at a fraction of the time and cost of competing wet-lab methodologies. The MEDIVAC technology will enable personalized cancer vaccine companies to make safer more efficacious vaccines in an affordable and clinically actionable timeframe, and will consequently help revolutionize the treatment of cancer. 
We believe the SME instrument is the ideal funding vehicle to enable OncoImmunity to overcome the remaining barriers to the market and establish the company as the leading provider of software solutions for guiding the design of cancer vaccines. Furthermore, the MEDIVAC software will help nurture and improve the competitiveness of European companies in the rapidly growing personalized cancer vaccine market, and ultimately help Europe to tackle a global cancer epidemic.
The Road to an Academic Medicine Career

To explore the relationship between gender and full-time faculty appointment in a national cohort of contemporary U.S. medical school graduates.The authors analyzed deidentified, individual records for the 1998-2004 national cohort of U.S. medical graduates using multivariate logistic regression to identify predictors of full-time faculty appointment through July 2009. They reported adjusted odds ratios (aOR) significant at P < .05.Of 66,889 graduates, 12,038 (18.0%) had held full-time faculty appointments. Among all graduates, women (aOR = 1.21) were more likely than men to have held faculty appointments. Among only male graduates, those who participated in research during college (aOR = 1.08), who entered medical school with greater planned career involvement in research (aOR = 1.08), and who authored/coauthored a research paper during medical school (aOR = 1.12) were more likely, and those with higher debt were less likely (aOR = 0.96), to have held faculty appointments. Among only faculty appointees, higher proportions of men than women had participated in medical school research electives (63.5% [3,899/6,138] versus 54.2% [3,197/5,900]; P < .001) and authored/coauthored research papers during medical school (44.1% [2,707/6,138] versus 33.6% [1,981/5,900]; P < .001); female faculty had reported higher debt at medical school graduation than had male faculty (P = .014).In this national cohort of U.S. medical graduates, women were more likely than men to have held full-time faculty appointments. However, male and female faculty appointees entered academic medicine with different research experiences and debt, possibly impacting their academic medicine career trajectories.
Functional activities of the Tsh protein from avian pathogenicEscherichia coli(APEC) strains

The temperature-sensitive hemagglutinin (Tsh) expressed by strains of avian pathogenic Escherichia (E.) coli (APEC) has both agglutinin and protease activities. Tsh is synthesized as a 140 kDa precursor protein, whose processing results in a 106 kDa passenger domain (Tsh(s)) and a 33 kDa β-domain (Tsh(β)). In this study, both recombinant Tsh (rTsh) and supernatants from APEC, which contain Tsh(s) (106 kDa), caused proteolysis of chicken tracheal mucin. Both rTsh (140 kDa) and pellets from wild-type APEC, which contain Tsh(β) (33 kDa), agglutinated chicken erythrocytes. On Western blots, the anti-rTsh antibody recognized the rTsh and 106 kDa proteins in recombinant E. coli BL21/pET 101-Tsh and in the supernatants from APEC grown at either 37°C or 42°C. Anti-rTsh also recognized a 33 kDa protein in the pellets from APEC13 cultures grown in either Luria-Bertani agar, colonization factor antigen agar, or mucin agar at either 26°C, 37°C, or 42°C, and in the extracts of outer membrane proteins of APEC. The 106 kDa protein was more evident when the bacteria were grown at 37°C in mucin agar, and it was not detected when the bacteria were grown at 26°C in any of the culture media used in this study. Chicken anti-Tsh serum inhibited hemagglutinating and mucinolytic activities of strain APEC13 and recombinant E. coli BL21/pET101-Tsh. This work suggests that the mucinolytic activity of Tsh might be important for the colonization of the avian tracheal mucous environment by APEC.
METHOD FOR THE PRODUCTION OF STACKS OF PLATES, ESPECIALLY COOLERS OR COOLER ELEMENTS COMPOSED OF STACKS OF PLATES

The invention relates to a method for producing stacks of plates, especially for producing coolers, cooling elements, or heat sinks which are composed of at least one stack of plates and are used for electric and/or optoelectric components.
Identification of Phenolic Compounds in Plum Fruits (<i>Prunus salicina</i> L. and <i>Prunus domestica</i> L.) by High-Performance Liquid Chromatography/Tandem Mass Spectrometry and Characterization of Varieties by Quantitative Phenolic Fingerprints

Plums (Prunus domestica L. and Prunus salicina L.) are edible fruits mostly consumed in America, China, and Europe. We have used LC-MS(n) to detect and characterize the phenolic compounds in plum varieties. Forty-one phenolics were detected comprising caffeoylquinic acids, feruloylquinic acid, p-coumaroylquinic acids, methyl caffeoylquinates, methyl p-coumaroylquinate, caffeoylshikimic acids, catechin, epicatechin, rutin, esculin, quercetin, quercetin-3-O-hexosides, dimeric proanthocyanidins, trimeric proanthocyanidins, caffeoyl-glucoside, feruloyl-glucoside, p-coumaroyl-glucoside, vanillic acid-glucosides, 3,4-dihydroxybenzoyl-glucoside, quercetin-3-O-pentosides, quercetin-3-O-rhamnoside, quercetin-pentoside-rhamnosides, and 3-p-methoxycinnamoylquinic acid. This is the first time when 3-p-methoxycinnamoylquinic acid is reported in nature. Chlorogenic acids and proanthocyanidins were the major phenolics present in plums. Furthermore, HPLC with DAD and chemical reaction detection was used to generate quantitative phenolic fingerprints from the fruit flesh of 33 plum varieties. The predominant compound was 3-caffeoylquinic acid in nearly all varieties studied; generally, however, the qualitative and quantitative profiles showed high diversity even among closely related progenies.