SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Flexible Organization in the OrcFS Relational File System for Efficient File Searching

The need for efficient organization of files grows with the computer storage capabilities. However, a classical hierarchical file system offers little help in this matter, excepting maybe the case of links and shortcuts. OrcFS proposes a solution to this problem. By redefining several file system concepts, it allows the user to set custom metadata, in the form of '(property,value)' pairs, to express relationships between files. Using it, the system automatically creates a classified view of its components, in which those having similar characteristics are grouped together. A virtual hierarchy is generated, which provides multiple access paths to the same file. This assures that the data can be classified in a more flexible way and the navigation can be done more intuitively. The traditional concept of directory is extended, to accommodate the user-defined properties. In OrcFS, both classical navigation and query interrogation are possible. The enhanced system is compliant with the Linux's VFS interface, thus no changes need to be made to existing applications and they may be used in OrcFS. A prototype of the project was implemented in user-space using the FUSE library to reimplement system calls. The performed tests proved that even if introducing new data in the OrcFS implies some overhead, this is negligible compared with the gain obtained when searching for files in an immense file tree structure.
Assessment of the Prevalence of Dental Anxiety among Palestinian Clients Attending Dental Clinics in Bethlehem City: Cross Sectional Study

Objective: To investigate the prevalence of dental anxiety as well as the relationships between socio-demographic data and perceived dental anxiety among Palestinian clients who attend dental clinics in Palestine. Materials and methods: Participants were recruited into the study from July to August, 2013 from several dental clinics. The modified Corah Dental Anxiety Scale (DAS) was used to measure dental anxiety among the study population. Results: One hundred and sixty four respondents returned the questionnaire after they filled it while in the reception area waiting their turn to see the dentists. Findings reveal that more than one third of the participants experienced a severe level of dental anxiety and were anxious mostly about tooth drilling and local anesthetic injection. Females experienced significantly more dental anxiety than males, but the relationships with other socio-demographic data (including education, place of residency, marital status, and visit habits ) were not significant. Conclusion: This study found high prevalence of dental anxiety which may represent special challenges to the dentists to treat individuals with dental fear. Non of the socio-demographic data except gender revealed statistically significant relation with dental anxiety among the study population Further studies are required to investigate the factors that may lead to increased the prevalence of this phenomena among the Palestinian clients.
Evaluation of a Health Coaching Course for Providers and Staff in Veterans Health Affairs Medical Facilities

Background:The purpose of this study was to determine whether a health coaching (HC) course for providers and staff in Veterans Health Affairs medical facilities resulted in increased attitudes toward, intentions to use, and actual use of HC. Methods: A Whole Health Coaching Course was developed and implemented in national sites in 2014. A pre-post intervention group only design was used to assess changes in HC outcomes, including use of HC skills. Results: There were large pre- to posttest increases in preparedness and self-efficacy that were sustained at follow-up. Initial small increases in attitudes toward patient-centered care and intentions to use HC skills were not sustained at follow-up. There was a medium-sized increase in actual use of HC skills between pre-test and follow-up. Conclusions: Findings suggest that participation in the HC course is an effective means for providers and staff to increase preparedness, self-efficacy, and actual use of health coaching skills.
Necessity of Lysophosphatidic Acid Receptor 1 for Development of Arthritis

Lysophosphatidic acid (LPA) is a bioactive lipid that binds to a group of cell surface G protein-coupled receptors (LPA receptors 1-6 [LPA1-6 ]) and has been implicated as an important mediator of angiogenesis, inflammation, and cancer growth. This study was undertaken to analyze the effects of LPA1 on the development of arthritis.Expression of LPA receptors on synovial tissue was analyzed by immunohistochemistry and quantitative reverse transcription-polymerase chain reaction. The effects of abrogation of LPA1 on collagen-induced arthritis (CIA) were evaluated using LPA1 -deficient mice or LPA1 antagonist. Migrating fluorescence-labeled CD11b+ splenocytes, which were transferred into the synovium of mice with CIA, were counted. CD4+ naive T cells were incubated under Th1-, Th2-, or Th17-polarizing conditions, and T helper cell differentiation was assessed. Osteoclast formation from bone marrow cells was examined.LPA1 was highly expressed in the synovium of patients with rheumatoid arthritis (RA) compared with that of patients with osteoarthritis. LPA1 -deficient mice did not develop arthritis following immunization with type II collagen (CII). LPA1 antagonist also ameliorated murine CIA. Abrogation of LPA1 was associated with reductions in cell infiltration, bone destruction in the joints, and interleukin-17 production from CII-stimulated splenocytes. Infiltration of transferred CD11b+ macrophages from LPA1 -deficient mice into the synovium was suppressed compared with infiltration of macrophages from wild-type mice. LPA1 antagonist inhibited the infiltration of macrophages from wild-type mice. Differentiation into Th17, but not Th1 or Th2, and osteoclast formation were also suppressed under conditions of LPA1 deficiency or LPA1 inhibition in vitro.Collectively, these results indicate that LPA/LPA1 signaling contributes to the development of arthritis via cellular infiltration, Th17 differentiation, and osteoclastogenesis. Thus, LPA1 may be a promising target molecule for RA therapy.
Combining in vivo spectral biphoton imaging and multiparametric cytometry to characterize the dynamics of the innate immune response in a multiple sclerosis mouse model

Multiple sclerosis (MS) disease is dependent on an intricate interplay between the adaptive and innate immune systems. Nevertheless, none of the Food and Drug Administration-approved drugs target innate immune cells, because of their unclear roles in the disease process. However, innate immune cells implication in the MS disease is no longer put in doubt.
The mobilization, differentiation and spatial-temporal distribution of brain resident and recruited peripheral innate immune cells, in relation with clinical scores, will be analyzed, as an alternative source of disease biomarkers and therapeutic targets.
The project combines recent advances in (a) generation of multicolor transgenic reporter mice with subpopulations of cells expressing distinct fluorophores, (b) spectral bi-photon imaging to visualize the cells of interest directly in the spinal cord in living animals, at a subcellular resolution in real time, and (c) multiparametric flow cytometry to characterize over time inflammatory cell types in the spinal cord tissue after disease induction. 
The activated cells converging to the neuronal lesions, as well as the delay and the effect on the neurons, will be characterized. VEGF will also be tested as potential therapeutic drug, based on the known VEGF effects on neurons and immune cells. This data will provide new insights on MS disease setting up and implicated cells, correlated with clinical scores, neuronal damages and disease progression.
Comparison of overapproximation methods for stability analysis of networked control systems

The presence of a communication network in a control loop induces many imperfections such as varying transmission delays, varying sampling/transmission intervals and packet loss, which can degrade the control performance significantly and can even lead to instability. Various techniques have been proposed in the literature for stability analysis and controller design for these so-called networked control systems (NCSs). The goal of this paper is to survey a particular class of techniques using discrete-time models that are based on polytopic overapproximations of the uncertain NCS model and lead to stability conditions in terms of linear matrix inequalities (LMIs). We discuss the advantages and disadvantages of the existing techniques in both qualitative and quantitative manners. In particular, we apply all methods to a benchmark example providing a numerical comparison of the methods with respect to conservatism as well as numerical complexity.
MORPHIC FORMS OF COMPLEMENT FACTOR D INHIBITORS

This invention provides stable, highly crystalline forms of Complement factor D inhibitors Compound 1 and Compound 2 for advantageous therapeutic pharmaceutical efficacy and dosage form stability.
Staying Connected: Technology Use in Grandparent-grandchild Relationships

Despite the distance that often separates grandparents from their young adult grandchildren, the abundance of new technologies provides numerous means of connection for the grandparent-grandchild (GP-GC) dyad. The purpose of this study was to understand how grandparents use technology, namely text messaging and Facebook, in relationships with their young adult grandchildren. Specifically, the aim was to understand grandparents' purposes for using these technologies with their grandchildren, their motivations for using these technologies, and their perceptions of these technologies. Qualitative interviews were conducted with 23 grandparent participants and analyzed according to the procedures delineated in grounded theory analysis. Both text messaging and Facebook emerged as important tools for connection, as text messaging encourages more frequent communication and Facebook helps grandparents fill in the gaps about their grandchildren's lives. Furthermore, results indicated that grandparents' uses of text messaging, and to a lesser extent Facebook, are acts of accommodation to their grandchildren.
Morcilla de Burgos

Blood sausages elaboration is intimately linked to the slaughter process, which has been done throughout the Spanish geography for centuries. These products, known as morcillas, have gone from local consumption to gaining popularity and splendor, in response to a growing consumer demand for traditional and quality products. In these products, blood from the slaughtering process is mixed with different ingredientsIngredients, depending on the availability of the area, stuffed in natural casings and subjected to a thermal treatment. The enormous variety of ingredientsIngredients considered in its composition offers a wide range of textures, flavors, and tastes. Morcilla de Burgos is one of the most famous and known morcillas. This product, with onion and rice in its composition, has recently obtained a protected geographical indication (PGI)Protected geographical indication (PGI), in an attempt to protect their origin and elaboration process. In this chapter these aspects are described.
Anti implantation effects of Jatropha curcas crude oil when fed to pregnant Sprague dawley rats during the early gestation period

Jatropha curcas is a species of flowering plants in the spurge family, Euphorbiaceae. The seeds contain 27-40% oil consisting of curcin and tetramethylpyrazine which are toxic and cause abortion, fetotoxicity and teratogenic effects if consume during pregnancy. Twenty four Sprague dawley rats at early gestation weighing about 200-300g were randomized into four groups: Positive control group was orally administered with retinyl palmitate, negative control group with corn oil (vehicle),  treatment group with 0.7 ml/kg body weight of the oil and the normal group was given distilled water. Females were paired overnight with male rats and presence of sperm in the vaginal smears indicated positive mating and considered pregnant day 1. Rats were dosed orally once daily from day 1 till day 7 of gestation.  Maternal body weights were also recorded daily. Rats were euthanized by diethyl ether inhalation on day 8 and the uteri removed and stained with 1% ammonium sulphide. The number of implantation sites was counted and data obtained were analysed using SPSS. There is a significant reduction in number of implantation sites i.e., treatment groups, positive and negative control and normal group are 0.83±0.401, 4.5±0.428, 8.67±0.333, 9.17±0.307 respectively. There is also a significant difference between treatment and control group in maternal body weights. In addition, a high percentage (90%) of anti-implantation activity was recorded in treatment groups. The small number of implantation sites and high percentage of anti-implantation activity suggests that Jatropha curcas crude oil have anti-fertility effects when fed to pregnant rats during early gestation. Keywords: Jatropha curcas ; anti implantation; early pregnancy.
High dimensional heterogeneous data based animation techniques for southeast asian intangible cultural heritage digital content

Although computer animation technology has been extensively used for films and games, it remains largely labour-intensive and expensive, with recent blockbuster films (e.g. Avatar, Gravity) costing around $1 million per minute of footage. A lot of research efforts and technological breakthroughs are therefore necessary if it is to be widely applied to many low-cost applications, such as archiving and reproducing style-preserved intangible cultural heritage (ICH) contents. The project “AniAge” is designed to answer this very challenge, using Southeast Asian ICH as the main application. Southeast Asian ICHs, e.g. local dances and puppetry, are visually and culturally rich, but are unfortunately disappearing due to the globalized modernization. The overall aim of ""AniAge"" is two-fold. The first is to develop novel techniques and tools to reduce the production costs and improve the level of automation without sacrificing the control of the artists, in order to preserve the performing art related ICHs of Southeast Asia. This involves capturing and processing versatile visual performance data, which are heterogeneous in nature and gigantic in quantity. Two areas of technological innovation are aimed to be made, which are novel algorithms for 3D computer animation; and visual asset management with data analytics and machine learning techniques. The second is to promote knowledge exchange and dissemination between EU and Southeast Asian partners, with a view to fostering researchers and spreading knowledge. This will be achieved by having researchers participating in the well-designed research projects, workshops, seminars and open lectures. This consortium consists of six partners, two from the EU and four from Southeast Asia. Four work packages are designed, three for technological developments (digitalizing traditional performing arts - ""DigAge"", digital asset management - ""ManD"" and stylized animation production - ""AniX"") and one for dissemination (""Dissem"").
PROmoting the Governance of Regional Ecosystem ServiceS

The overall objective of the project is to initiate a process of policy change in the partners' regions improving the implementation of the policy instruments under Structural Funds programmes and other regional strategies dedicated to the conservation of biodiversity and the maintaining nature’s capacity to deliver the goods and services that we all need, through policy learning and capacity building activities. The policy instruments tackled by the project are the ERDF OPs at regional or national level and other regional strategies dealing with the protection and valuing biodiversity and ecosystem services. The approach proposed by the project is firmly based on policy learning and capacity building of the partner organizations and relevant stakeholders of the concerned policy subsystems, as it stimulates a collective multidimensional and dynamic exchange of experience. The project brings together local authorities and their associations, local development agencies, universities and research centres with a balanced mix between more and less developed regions and thought to asssure geographical balance. Exchange of experience is built on the partners' competences and experience in the design and implementation of policies protecting and valuing biodiversity and ecosystem services. The sub-objective is to contribute to capacity building and policy learning in the partners’ regions by supporting exchange of experience among relevant stakeholders, in order to:
- promote the measurement of the costs and benefits of ecosystem services derived from land use. 
- support the horizontal integration of the ecosystem concerns into the sectoral policies and plans at regional and/or national level.
- explore innovative financial and marketing mechanisms for payment for ecosystem services.  
- improve landscape governance for economic and environmental sustainability.
Taking a reflexive approach to gender equality for institutional transformation

TARGET will initiate institutional change in seven gender equality innovating institutions (GEIIs) in the Mediterranean basin – including research performing organisations (RPOs), research funding organisations (RFOs) and a network of universities. TARGET takes a reflexive approach which goes beyond the formal adoption of a gender equality plan by emphasising an iterative reflection of progress made as well as establishing a community of practice to effect institutional transformation. Actual change is the result of increased institutional willingness and capacity to identify, reflect on and address gender bias in a sustained way. Starting point and anchor of the process is a tailored Gender Equality Plan or Strategy (GEP/GES) in each GEII. TARGET will build the institutional capacity for a reflexive gender equality policy by: developing effective tools for each stage of the GEP/GES (audit, planning, implementation, monitoring, self-assessment) to be customised to the specific institution; supporting the development of competences to conduct a gender audit, to design, implement, monitor and self-assess a tailored GEP/GES; establishing a community of practice of relevant stakeholders within each GEII; initiating an organisational learning process within each GEII which combines self-assessment with GEP/GES evaluation. The TARGET countries have been characterised as relatively inactive in developing gender equality policies in R&I. To ensure that action taken has a multiplier effect, each GEII will undertake targeted dissemination activities to initiate a national/regional discourse on gender equality in R&I. Furthermore TARGET will develop new knowledge for institutions, practitioners and policymakers based on a comparative analysis of GEP implementation and sustainability to provide a basis for effective sharing of practice in both proactive and relatively inactive countries - taking into account differences in cultural, socio-economic and political settings.
COMUNIS
Inter-municipal cooperation for Strategic Steering of SME-oriented Location Development in the Alpine Space

In the Alps, the strategies of commercial development on the municipal level have been to react to single cases in the short term. A coordinated and concerted strategy using the regional and local potentials is missing. COMUNIS aims at developing a well-defined integrative and cooperative strategy for Commercial Location Development (CLD) and enhancing inter-municipal and intra-territorial cooperation to overcome individualistic attempts of problems solution on the level of single municipalities. COMUNIS will provide broadly adaptable guidelines to apply this strategy and practical instruments for the assessment of the local and regional demand for and the steering of commercial development with particular focus on diversification and efficiency of economic activities, environmental and social concerns, human and cultural capital. Furthermore the project will result in a transnational knowledge management and establish sustainable structures for managing CLD in the pilot regions.
The noise-induced frequency shift in spin-torque oscillators

In the report the dependence of mean angular frequency in spin-torque nano-oscillators (STNO) on the intensity of external magnetic field fluctuations and other parameters is analyzed. Using the analytical expression for polar angle distribution and numerical simulations it is shown that the deviation of mean frequency can be considerable and always increase with the approach to the boundaries of oscillation regime. It is also shown that this effect starts to disappear when the correlation time of noise becomes greater than the inverse angular frequency. This last phenomenon leads to the asymmetry of the dependence of mean angular frequency deviations from the parameters of the STNO for non-white noise.
Beyond Technology: Demand-Side Solutions for Climate Change Mitigation

The assessment literature on climate change solutions to date has emphasized technologies and options based on cost-effectiveness analysis. However, many solutions to climate change mitigation misalign with such analytical frameworks. Here, we examine demand-side solutions, a crucial class of mitigation options that go beyond technological specification and cost-benefit analysis. To do so, we synthesize demand-side mitigation options in the urban, building, transport, and agricultural sectors. We also highlight the specific nature of demand-side solutions in the context of development. We then discuss key analytical considerations to integrate demand-side options into overarching assessments on mitigation. Such a framework would include infrastructure solutions that interact with endogenous preference formation. Both hard infrastructures, such as the built environment, and soft infrastructures, such as habits and norms, shape behavior and as a consequence offer significant potential for reducing overall energy demand and greenhouse gas emissions. We conclude that systemic infrastructural and behavioral change will likely be a necessary component of a transition to a low-carbon society.
‘Smart’ gold nanoshells for combined cancer chemotherapy and hyperthermia

Nanomaterials that circulate in the body have great potential in the diagnosis and treatment of diseases. Here we report that 'smart' gold nanoshells can carry a drug payload, and that their intrinsic near-infrared (NIR) plasmon resonance enables the combination of chemotherapeutic and hyperthermia therapies. The 'smart' gold nanoshells (named DOX/A54@GNs) consist of (a) gold nanoshells (GNs) with NIR plasmon resonance, which not only act as nanoblocks but also produce local heat to allow hyperthermia; (b) an anticancer drug, doxorubicin (DOX), which was conjugated onto the nanoblocks by pH-dependent biodegradable copolymer thiol poly(ethylene glycol) derivatives via carbamate linkage; and (c) the targeting peptide A54 (AGKGTPSLETTP) to facilitate its orientation to liver cancer cells and enhance cellular uptake. The conjugated DOX was released from the DOX/A54@GNs much more rapidly in an acidic environment (pH 5.3) than in a neutral environment (pH 7.4), which is a desirable characteristic for intracellular tumor drug release. DOX-modified GNs showed pH-dependent release behavior, and the in vitro cell uptake experiment using ICP-AES and microscopy showed greater internalization of A54-modified GNs in the human liver cancer cell line BEL-7402 than of those without A54. Flow cytometry and fluoroscopy analysis were conducted to reveal the enhanced cell apoptosis caused by the A54-modified GNs under combined chemotherapeutic and hyperthermia therapies. These results imply that DOX/A54@GNs could be used as a multifunctional nanomaterial system with pH-triggered drug-releasing properties for tumor-targeted chemotherapy and hyperthermia.