SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
COSMETIC STICK

The invention relates to a mechanical cosmetic stick comprising a sleeve (20) in which a stick (22) is accommodated, said stick being held on a pressing element which can be axially moved in relation to the sleeve. Limbs (28) are placed against the stick which should hold the stick on the pressing element. At least one of the limbs comprises a projection (30) which is radially oriented toward the stick. In conjunction with a step or ramp (40) which has a narrowing diameter and which is situated on the inner wall of the sleeve, the sleeve penetrates into the stick (22) when the pressing element is extended and when the limb (28) of said projection (30) subsequently slides therewith, whereby the stick is fixed.
Metal oxide high energy capacitors

For the further acceleration of transport electrification, the cost of energy storage needs to be reduced while also delivering more range, faster charging times, less weight. These opposing goals cannot be met by batteries alone. We propose an alternative, ultracapacitor-derived solution, which in some applications replaces batteries and in others supports the batteries to deliver on those opposing goals.

The X-Cap is a game changer product for the mobility market bridging the gap between power and energy devices to speed up electric and hybrid vehicle take-up as well as support grid stability required for further integration of renewables into the electric grid. X-Cap also has the specifications to replace the lead acid battery. The combined market size for related applications amounts to € 66.6 Bn. 

Ultracapacitors are energy storage devices with much longer lifetime, higher power density and lower environmental impact than Lithium Ion Batteries, but with reduced energy density. Increasing the energy density of Ultracapacitors significantly increases their field of application, but due to their physical set up, this increase has so far proved difficult. 

Within the presented project, a novel energy storage material is to be applied in Ultracapacitor cells in order to create a device capable of delivering high power energy storage with increased storage capability beyond the theoretical limit of classical Ultracapacitors.
Promjene ciljeva Zajedničke poljoprivredne politike s naglaskom na razdoblje nakon 2020.

The Common Agricultural Policy (CAP) established in 1962 is the most important public policy to which a large part of the European Union budget goes. After 30 years of stability, the CAP is undergoing its first significant reform in 1992, better known as the MacSharry reform. This is followed by Agenda 2000 (1999), Mid-Term Review (MTR 2003), Health-Check (2008), CAP reform 2013-2020. and CAP post 2020 reform. In the early 1990s, through trade negotiations under the GATT (today's WTO), an agreement was reached at the international level, the Agreement on Agriculture, which set out acceptable and unacceptable agricultural policy measures. With the change in society's attitudes towards agriculture and its financing, over the past 30 years, the goals of agricultural policy have changed, and they now include environmental protection, landscape, animal welfare, quality and food safety.
Impact of Housing and Financial Wealth on Household Consumption:Evidence from Micro-Data in China

Using newly released China Health and Retirement Longitudinal Study(CHARLS),this paper explores impact of assets on household consumption in China.The micro-data permits us to analyze the impact of wealth on both durable and non-durable consumption and to compare wealth effects derived from gross versus after-debt measures of financial and housing wealth.The main results show that among homeowners,the housing wealth elasticities are estimated in the range of 0.07-0.09 while the estimated elasticities of consumption spending with respect to financial wealth are smaller in magnitude and are in the range of 0.02.In addition,the wealth effect seems to matter more for younger households,the wealth effect seems to matter more for urban household.Households borrowing capacity play a negligible role in wealth effects.
Targeting neurosteroid synthesis as a therapy for schizophrenia-related alterations induced by early psychosocial stress

Cogent evidence has shown that schizophrenia vulnerability is enhanced by psychosocial stress in adolescence, yet the underpinnings of this phenomenon remain elusive. One of the animal models that best capture the relationship between juvenile stress and schizophrenia is isolation rearing (IR). This manipulation, which consists in subjecting rats to social isolation from weaning through adulthood, results in neurobehavioral alterations akin to those observed in schizophrenia patients. In particular, IR-subjected rats display a marked reduction of the prepulse inhibition (PPI) of the startle reflex, which are posited to reflect imbalances in dopamine neurotransmission in the nucleus accumbens (NAcc). We recently documented that the key neurosteroidogenic enzyme 5α-reductase (5αR) plays an important role in the dopaminergic regulation of PPI; given that IR leads to a marked down-regulation of this enzyme in the NAcc, the present study was designed to further elucidate the functional role of 5αR in the regulation of PPI of IR-subjected rats.We studied the impact of the prototypical 5αR inhibitor finasteride (FIN) on the PPI deficits and NAcc steroid profile of IR-subjected male rats, in comparison with socially reared (SR) controls.FIN (25-100 mg/kg, i.p.) dose-dependently countered IR-induced PPI reduction, without affecting gating integrity in SR rats. The NAcc and striatum of IR-subjected rats displayed several changes in neuroactive steroid profile, including a reduction in pregnenolone in both SR and IR-subjected groups, as well as a decrease in allopregnanolone content in the latter group; both effects were significantly opposed by FIN.These results show that 5αR inhibition counters the PPI deficits induced by IR, possibly through limbic changes in pregnenolone and/or allopregnanolone concentrations.
Co2 geological pilots in strategic territories - pilotstrategy

PilotSTRATEGY focuses on advancing understanding of deep saline aquifer (DSA) resources for geological CO2 storage in five European industrial regions in Southern and Eastern Europe.  DSAs have much promise and potential for CO2 storage, but despite their high potential storage capacity, they are not well studied. There is a need to increase confidence and maturity of understanding of these sites.

PilotSTRATEGY will investigate DSA in detail in three regions of Southern Europe: Paris Basin (France), Lusitanian Basin (Portugal) and Ebro Basin (Spain).  This will include acquisition of new data, detailed geo-characterisation, feasibility studies and preliminary design or pre-front end engineering and design studies.  At the end of the project, the level of site characterisation in these three regions will be sufficient to allow a final investment decision to be made and for storage permitting and project approval to be obtained. 

In two further regions of Eastern Europe, West Macedonia (Greece) and Upper Silesia (Poland), PilotSTRATEGY will increase the maturity and confidence level of understanding of DSA storage resources, based on new available data, reprocessing of old data and new dynamic simulation studies. This will enable these regions to start planning to develop their storage resources.

Recognising the social challenge of implementing geological CO2 storage, PilotSTRATEGY will take a systemic approach and analyse the factors that influence societal acceptance of storage sites, to develop methods for societal engagement. Regional stakeholders and the local public will be involved in developing recommendations and concepts as part of the pilot conceptualization and design.  At the same time, PilotSTRATEGY will run a series of dialogues, “Talk with Authorities,” to support capacity building in local authorities and build policy makers’ awareness of geological CO2  storage, particularly the role of CCUS in just, net-zero transitions in all regions.
The role of hydrogen in the optimal design of off-grid hybrid renewable energy systems

The optimal design of off-grid hybrid renewable energy systems (HRESs) is a challenging task, which often involves conflicting goals to be faced. In this work, levelized cost of energy (LCOE) and CO2 emissions have been addressed simultaneously by using the ε-constraint method together with the particle swarm optimization (PSO) algorithm. Cost-emissions Pareto fronts of different HRES configurations were developed to gain greater awareness about the potential of renewable-based energy systems in off-grid applications. Various combinations of the following components were investigated: photovoltaic panels, wind turbines, batteries, hydrogen and diesel generators. The hydrogen-based system comprises an electrolyzer to convert the excess renewable energy into hydrogen, a pressurized tank for H2 storage and a fuel cell for the reconversion of hydrogen into electricity during renewable energy deficits. Electrolyzer and fuel cell devices were modelled by means of part-load performance curves. Size-dependent costs and component lifetimes as a function of the cumulative operational duty were also considered for a more accurate techno-economic assessment. The proposed methodology was applied to the Froan islands (Norway), which were chosen as a reference case study since they are well representative of many other insular microgrid environments in Northern Europe. Results from the sizing simulations revealed that energy storage devices are key components to reduce the dependency on fossil fuels. In particular, the hydrogen storage system is crucial in off-grid areas to enhance the RES penetration and avoid a sharp increase in the cost of energy. Hydrogen, in fact, allows the battery and RES technologies not to be oversized, thanks to its cost-effective long-term storage capability. Concerning the extreme case with no diesel, the cheapest configuration, which includes both batteries and hydrogen, has an LCOE of 0.41 €/kWh. This value is around 35% lower than the LCOE of a system with only batteries as energy storage.
Youth exposure to alcohol advertising on television in the UK, the Netherlands and Germany

Exposure of young people to alcohol advertising is a risk factor for underage drinking. This study assessed youth exposure to television alcohol advertising in the UK, the Netherlands and Germany, from December 2010 to May 2011.A negative binomial regression model predicted number of alcohol advertisements from the proportion of the television viewership in each age group. This allowed comparison of alcohol advertisement incidence for each youth age category relative to an adult reference category.In the UK, those aged 10-15 years were significantly more exposed to alcohol advertisements per viewing hour than adults aged ≥ 25 years [incidence rate ratio (IRR) = 1.11; 95% confidence interval (95% CI): 1.06, 1.18; P < 0.01]; in the Netherlands, those aged 13-19 years were more exposed per viewing hour than adults aged ≥ 20 years (IRR = 1.29; 95% CI: 1.19, 1.39; P < 0.01). Conversely, in Germany, those aged 10-15 years were less exposed to alcohol advertisements than adults aged ≥ 25 years (IRR = 0.79; 95% CI: 0.73, 0.85; P < 0.01). In each country, young children (aged 4-9 years in the UK and Germany, 6-12 years in the Netherlands) were less exposed than adults.Adolescents in the UK and the Netherlands, but not Germany, had higher exposure to television alcohol advertising relative to adults than would be expected from their television viewing. Further work across a wider range of countries is needed to understand the relationship between national policies and youth exposure to alcohol advertising on television.
ANEMA AND CORE S.A.S. — PEC: ANEMAECOREVENAFRO@PEC.IT

REQUEST FOR FACILITATION REFERRED TO IN THE PUBLIC NOTICE OF SMALL GRANTS TO SMES SUSPENDED OR WITH A SEVERE FALL IN TURNOVER
Preliminary radiological safety assessment for decommissioning of thoria dissolver of the 233U pilot plant, Trombay

The thoria dissolver, used for separation of (233)U from reactor-irradiated thorium metal and thorium oxide rods, is no longer operational. It was decided to carry out assessment of the radiological status of the dissolver cell for planning of the future decommissioning/dismantling operations. The dissolver interiors are expected to be contaminated with the dissolution remains of irradiated thorium oxide rods in addition to some of the partially dissolved thoria pellets. Hence, (220)Rn, a daughter product of (228)Th is of major radiological concern. Airborne activity of thoron daughters (212)Pb (Th-B) and (212)Bi (Th-C) was estimated by air sampling followed by high-resolution gamma spectrometry of filter papers. By measuring the full-energy peaks counts in the energy windows of (212)Pb, (212)Bi and (208)Tl, concentrations of thoron progeny in the sampled air were estimated by applying the respective intrinsic peak efficiency factors and suitable correction factors for the equilibration effects of (212)Pb and (212)Bi in the filter paper during the delay between sampling and counting. Then the thoron working level (TWL) was evaluated using the International Commission on Radiological Protection (ICRP) methodology. Finally, the potential effective dose to the workers, due to inhalation of thoron and its progeny during dismantling operations was assessed by using dose conversion factors recommended by ICRP. Analysis of filter papers showed a maximum airborne thoron progeny concentration of 30 TWLs inside the dissolver.
New food for special medical purposes to nutritionally manage myotonic dystrophy type 1

Myotonic Dystrophy type 1 (DM1) is the most common and multisystemic neuromuscular rare disease affecting 1 million people worldwide, 100,000 EU citizens, who still have no cure or treatment available. 
In the light of the ´Leave No-one Behind´ commitment behind Sustainable Development Goals and particularly, the dietary management approach may provide a unique option for rare disease patients through Foods for special medical purposes (FSMP), foods (not drugs) intended for the dietary management of individuals who suffer from certain diseases. The main goal of the present project is to compile in human evidences that MYODM’s food for special medical purposes is a unique approach to improve DM1 patients’ Quality of Life through a pilot clinical trial for foods and supplements sponsored by Myogem and leaded by Dr. Adolfo López de Munain, a worldwide neurologist specialized in DM1.
MYOGEM is the current licensee of the patents WO2016075288 A1 and WO2016075285 A1, which disclosed the effects of some methylxanthines on DM1. Owning the Intellectual Property Rights over the present solution is one of the main competitive advantages of MYOGEM.  MYOGEM is the first and unique company worldwide who launched a food supplement for a rare disease in May 2017. However, as food supplement MYODM faces the problem that DM1 community, either neurologists and patient associations, claim for in human data in order to broadly prescribe and consume the product. To overcome this barrier, and gain market confidence, MYOGEM aims to perform a Feasibility pilot clinical trial to demonstrate MYODM’s effect on a small cohort of 10-15 DM1 patients in order to commercially upgrade our current product “food supplement” to “food for special medical purpose”, from now on referred as MYODM-FSMP, that will reach the market in less than one year after the present project ends. 
By launching the new MYODM-FSMP product, a 5.5 M€ SOM is expected in 5 years after the project. Two SoE have been awarded.
Selecting, creating and modifying embryos: the ethics of new reproductive genetic technologies

For over three decades reproductive technologies have been available which allow parents to select between embryos based on their genetic makeup. Soon two novel ways of influencing a child’s genome could also become available. In 2013, personal genomics company 23andMe received a patent to a technology called ‘Gamete Donor Selection Based on Genetic Calculations.’ This technology would allow individuals accessing assisted reproductive services to choose between sperm or egg donors based on the likelihood of the embryos having a particular genetic makeup. Technologies like this allow parents to create rather than select embryos with desirable genetic characteristics. In addition genetic engineering technologies continue to improve. The recently developed ‘CRISPR’ technique provides a more precise way of altering the genome than previous methods, and is the first modification technology with real potential to be used on human embryos. Technologies like this may allow parents to modify the genetic material of existing embryos. 

These developments are seen by some as raising very serious ethical worries, and by others as promising to promote human flourishing. Therefore there is an urgent need to give them systematic ethical scrutiny. 

If elected to this fellowship I will conduct a rigorous review of embryo creation, modification and section technologies and their ethical, political and philosophical implications. Built on an in-depth understanding of the science behind these technologies, my project will encompass an analysis of relevant philosophical and ethical issues, before delivering practical policy suggestions. This project will be the first extensive overview of the ethics of embryo creation technologies, the specific ethical issues raised by the CRISPR technique, and the moral and philosophical differences between embryo selection, creation and modification technologies.
Adaptation, learning and training for spatial hearing in complex environments

In everyday situations, humans are exposed to multiple concurrent stimuli in complex, continuously changing environments. To correctly extract relevant information, they adapt their processing to reflect the specifics of the current scene, and they learn from previous experience to improve the perceptual strategies used. The current project proposes to perform a series of behavioral experiments, brain imaging studies, and computational modeling 1) to study the auditory mechanisms of adaptation to new reverberant environments for speech processing, sound localization, and learning of new phonetic categories, and 2) to study how attention and mechanisms of implicit and explicit learning are used to cope with complex listening environments. The results will be important, e.g., for development of new prosthetic devices and new virtual reality technologies. Here, they will be used to develop a brain training game that can improve impaired listeners’ performance in complex environments. An additional goal of the proposal is to obtain new knowledge and skills related to studying human perceptual processes and the corresponding neural mechanisms. Skills to perform sensory learning research, psychophysics, non-invasive brain imaging (EEG and fMRI), and computational modeling will be exchanged during the secondments. Also, a series of workshops will be organized to train new researchers to perform research in computational and cognitive neuroscience, with additional goal of enhancing the exchange of information among participants and sharing new results obtained in this project. The project consortium consists of academic, research, medical, and small enterprise organizations based in the EU and USA. The participants have complementary skills necessary to achieve all the defined goals. Their collaboration on this project will result in strengthening of the European Research Area and in establishing new long-term collaborations between EU and US researchers.
Characterization and transport of aerosols over the Bay of Bengal during the winter monsoon: a comparative study using in-situ and satellite measurements

Natural processes, such as dust storms and sea salt spray, and anthropogenic activities, such as the burning of fossil fuels and biomass, introduce aerosols into the atmosphere. Their concentration, geographic distribution and particle size promote significant climatic consequences. Aerosol transport processes, from landmasses to oceans, are scarcely understood because of inadequate in-situ observations. This study reports the results of spectral aerosol optical depth (AOD) measurements using a five-channel (380, 440, 500, 675 and 870 nm) handheld MICROTOPS Sun-photometer used during a sea-truth data collection campaign conducted in the central Bay of Bengal (BOB) during the northeastern monsoon period (10 November to 13 December 2007). For the entire cruise period, the mean values of the daily average of the AODs at 500 nm and 870 nm were 0.39 ± 0.065 and 0.22 ± 0.047, respectively, the mean value of the Angstrom exponent (α) was 1.23 ± 0.2 and the turbidity parameter (β) was 0.183 ± 0.044. A smaller α value together with a larger β value suggests the presence of an abundance of smaller aerosol particles near the coast. An air mass back-trajectory analysis was undertaken to identify the potential source regions of the aerosols. Analysis of the results demonstrated the effect of the aerosol transport and source regions on the spectral behaviour of the AODs. In-situ measured AOD (550 nm) and α (550 nm, 865 nm) values were further compared with Moderate Resolution Imaging Spectroradiometer (MODIS)-derived parameters. The in-situ and MODIS-derived AOD values were found to be in good agreement, with a coefficient of determination (R2) of 0.78 and a standard error of 0.05, while the R2 for α was 0.68 with a standard error of 0.14.
Peripheral Visual Fields in ABCA4 Stargardt Disease and Correlation With Disease Extent on Ultra-widefield Fundus Autofluorescence

To evaluate the disease extent on ultra-widefield fundus autofluorescence (UWF-FAF) in patients with ABCA4 Stargardt disease (STGD) and correlate these data with functional outcome measures.Retrospective cross-sectional study.Setting: Kellogg Eye Center, University of Michigan.Sixty-five patients with clinical diagnosis and proven pathogenic variants in the ABCA4 gene. Observational Procedures: The UWF-FAF images were obtained using Optos (200 degrees) and classified into 3 types. Functional testing included kinetic widefield perimetry, full-field electroretinogram (ffERG), and visual acuity (VA). All results were evaluated with respect to UWF-FAF classification.Classification of UWF-FAF; area comprising the I4e, III4e, and IV4e isopters; ffERG patterns; and VA.For UWF-FAF, 27 subjects (41.5%) were classified as type I, 17 (26.2%) as type II, and 21 (32.4%) as type III. The area of each isopter correlated inversely with the extent of the disease and all isopters were able to detect differences among UWF-FAF types (IV4e, P = .0013; III4e, P = .0003; I4e, P < .0001 = 3.93e-8). ffERG patterns and VA were also different among the 3 UWF-FAF types (P < .001 = 6.61e-6 and P < .001 = 7.3e-5, respectively).Patients with widespread disease presented with more constriction of peripheral visual fields and had more dysfunction on ffERG and worse VA compared to patients with disease confined to the macula. UWF-FAF images may provide information for estimating peripheral and central visual function in STGD.
Experimental study of the heat transfer characteristics of a new-type flat micro-heat pipe thermal storage unit

Abstract In this study, the heat transfer characteristics of a new-type flat micro-heat pipe thermal storage unit, which uses a moderate-temperature paraffin as heat storage phase change material, were investigated. The basic structure, working principle, and design concept of the thermal storage unit were discussed. Experiments were conducted to study the charging and discharging heat transfer processes of the thermal storage unit under different inlet temperatures and flow rates for the cold/hot heat transfer fluid (HTF). Experimental results show that the performance of the thermal storage unit was steady and efficient during heat charging and discharging, and the average charging and discharging powers of the thermal storage unit were approximately 658 and 894 W, respectively, under specific experimental parameters.