SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Role of multi-slice CT coronary angiography in evaluating the different patterns of coronary artery disease in patients with unstable angina

Abstract Objective To evaluate the different patterns of coronary artery disease among patients with unstable angina by the role of multislice CT coronary angiography. Patients and methods From September 2013 to May 2014, 40 patients complaining from unstable angina showing initial negative ECG and troponin enzyme underwent a multi-slice CT coronary angiography. Each patient underwent a non-contrast scan to determine the calcium score, then a contrast enhanced ECG gated scan, then the obtained axial images were reconstructed on an advanced workstation. Finally, a systematic analysis of the coronary artery lesions was performed. Results 9 patients had normal CTCA, 5 had dense coronary calcification, 16 had no significant obstructive lesion and 10 patients had significant CAD. A total of 60 coronary vessels were found to have plaques. The number of patients with multi-vessel disease was significantly higher than those with single-vessel disease at the time of diagnosis. Conclusion Non-invasive multi-slice CT coronary angiography is a reliable technique of high ability to detect coronary artery disease and estimate the degree of obstruction, number of affected arteries and the pattern of their affection and can be used in workup in patients with unstable angina.
Reducing energy dependency in Atlantic Area water networks

The water industry is the fourth most energy intensive sector in the Atlantic Area, responsible for significant contributions to climate change and reductions in the competitiveness due to the associated costs, but with the potential to generate local renewable energy in water network infrastructure. At present significant potential exists to save energy, costs and environmental impacts in Atlantic Area water networks, but technological, institutional and social barriers prevent the exploitation of this resource. 
The REDAWN project will develop technology and policy, and raise awareness to overcome these barriers, improving the energy efficiency of water suppliers and users in the region. The aim of this project is to improve the energy efficiency of water networks through the installation of innovative micro-hydropower technology. This technology will recover wasted energy in existing pipe networks across irrigation, public water supply, process industry, and waste-water network settings. REDAWN will develop an adequate institutional, social and technological environment to foster greater resource efficiency in water networks, including:
• Completion of an energy recovery resource assessment in water networks in the Atlantic Area;
• Completion of an economic/environmental impact assessment of this technology on the region;
• Development of design guidelines and support tools for hydropower energy recovery in drinking water, waste water, irrigation and process industry 
sectors;
• Development of policy and institutional support tools to increase the implementation of energy recovery projects;
• Quantification of the societal impacts of hydropower energy recovery in water networks;
• Widespread dissemination and promotion of energy efficiency in AA water networks.
The effects of engineered nanoparticles on the cellular structure and growth of<i>Saccharomyces cerevisiae</i>

In order to study the effects of nanoparticles (NPs) with different physicochemical properties on cellular viability and structure, Saccharomyces cerevisiae were exposed to different concentrations of TiO2-NPs (1-3 nm), ZnO-NPs (<100 nm), CuO-NPs (<50 nm), their bulk forms, Ag-NPs (10 nm) and single-walled carbon nanotubes (SWCNTs). The GreenScreen assay was used to measure cyto- and genotoxicity, and transmission electron microscopy (TEM) used to assess ultrastructure. CuO-NPs were highly cytotoxic, reducing the cell density by 80% at 9 cm(2)/ml, and inducing lipid droplet formation. Cells exposed to Ag-NPs (19 cm(2)/ml) and TiO2-NPs (147 cm(2)/ml) contained dark deposits in intracellular vacuoles, the cell wall and vesicles, and reduced cell density (40 and 30%, respectively). ZnO-NPs (8 cm(2)/ml) caused an increase in the size of intracellular vacuoles, despite not being cytotoxic. SWCNTs did not cause cytotoxicity or significant alterations in ultrastructure, despite high oxidative potential. Two genotoxicity assays, GreenScreen and the comet assay, produced different results and the authors discuss the reasons for this discrepancy. Classical assays of toxicity may not be the most suitable for studying the effects of NPs in cellular systems, and the simultaneous assessment of other measures of the state of cells, such as TEM are highly recommended.
Ultrasensitive quantification of proteins based on amplification of dna displaced from dna aptamer duplex using semiconductor technology

The life expectancy in both EU and US fell in 2015. A third of premature deaths could be preventable and large part is due to obesity – a major risk factor for many chronic diseases including diabetes. Worldwide about 40% of adults are overweight and 13% obese. Regulation of food metabolism is becoming one of the main issues relevant to human health today. Obesity is preventable, however there are no currently available non-invasive and cost-effective obesity treatments, pointing to the need of novel diagnostic and prognostic tests. Leptin, a gut-hormone protein, has been shown to be crucial in regulating appetite and weight. Its concentration is proportional to the body fat mass, and changes at a greater rate compared to weight loss, therefore it can be used as a key measure of diet efficiency. Strong correlation between plasma and salivary leptin levels allows monitoring leptin in saliva, and provides point-of-care (PoC) personalised insight into the success of individual weight loss programs.
During our ERC Synergy Grant we have developed an aptamer based approach to perform quantitative detection of protein molecules using nucleic acid amplification to overcome the complexities of current methods to enable PoC detection. The key idea (patent pending) is to amplify and quantify DNA displaced from DNA-aptamer complexes by Leptin molecules with real-time Loop Mediated Isothermal Amplification. We will use an Ion Sensitive Field Effect Transistor lab-on chip arrays. Now we need funds to further develop this technology and create a PoC platform to provide linear label-free ultrasensitive protein detection, reducing complexity, time-to-result and cost of the assay. Furthermore, the development of this novel molecular method will enable quantification of a broader number of protein targets and create one of the most sensitive PoC techniques for protein quantification, with applications far beyond appetite control (obesity, anorexia etc) management.
Sharing the burden for climate change mitigation in the Canadian federation

Dividing the burden for greenhouse gas abatement amongst the provinces has proven challenging in Canada, and is a major factor contributing to Canada's poor historic performance on greenhouse gas abatement. As the country aims to achieve substantial cuts to emissions over the next decade and by mid-century, such burden sharing considerations are likely to be elevated in importance. This paper uses a calibrated multi-region multi-sector computable general equilibrium model to compare a number of archetypal rules for sharing the burden of a joint commitment amongst members for the case of greenhouse gas reductions in Canada. Because of the substantial heterogeneity amongst Canadian provinces, these different burden sharing rules imply signifcantly different relative abatement effort amongst provinces, and also signifcantly different welfare implications. When emission permits are allocated on an equal per capita basis, welfare is increased in Ontario, British Columbia, Quebec, and Manitoba, and signifcantly reduced in Alberta and Saskatchewan. In contrast, when emission permits are allocated based on historic emissions, Alberta and Saskatchewan are made better off, and Ontario, British Columbia, Quebec, and Manitoba are made worse off. We compare these archetypal burden sharing rules to existing provincial emission reduction commitments, and find that none of the standard burden sharing rules comes close to existing commitments. We argue that the debate on burden sharing of greenhouse gas abatement in Canada could be objectified if informed by coherent quantitative analysis such as the one presented here.
Metasurface-Integrated light detection and ranging

The “i-LiDAR” PoC project addresses the realisation of high-resolution and high-frame rate imaging systems. Relying on a combination of newly developed planar optical components, known as metasurfaces to achieve large deflection angles, with existing opto-mechanical systems, known for their high-speed light modulations, we will realize new light detection and ranging devices. The proof of concept devices are of great interests for both civil and military applications. Improving the scanning rate by orders of magnitude while preserving a continuous beam steering capabilities, could enable new high-speed applications. Fast imaging i-LiDAR system could be of interest for self-driven cars, giving them sufficiently fast ‘‘visual’’ recognition in order to adjust the driving conditions in real time, for example to drive on highways
Interaction of pentaphenylantimony with carboranedicarboxylic acid

Abstract The reaction of equimolar amounts of pentaphenylantimony with carboranedicarboxylic acid in toluene lead to tetraphenylantimony carborane carboxylate (1) in high yield. When using 2:1 M ratio of initial reagents, bis(tetraphenylantimony) carborane bis(carboxylate) (2) was obtained in 94% yield. Sb atoms in 1 and 2 form the distorted trigonal-bipyramidal coordination with carboxylate and phenyl ligands in axial positions (CaxialSbO are 174.06(12)° and 175.74(13)°, 176.77(13)° respectively). The Sb–O и Sb–C bond distances are 2.469(3) A and 2.095(4)−2.136(4) A in 1 and 2.275(3), 2.364(3) and 2.112(4)−2.173(4) A in 2. There are no intramolecular contacts in 1 between Sb and О atom of CO group. In 2 the bond distances Sb⋯O(=C) (3.203(4) и 3.213(4) A) are much less than a sum of van der Vaals radii of Sb and O atoms. Crystal structures of 1 and 2 are characterized by weak intermolecular hydrogen bonds H⋯O (2.25–2.53 and 2.54 A, respectively).
Analysis of Shijiazhuang Urbanization Effect on the Ecological Environment

Urbanization needs the sustained and healthy economic and social development as the premise, the coordinated development and healthy development cannot do without the ecological environment. The coordinated development of ecological environment requires scientific and effective control and prevention on the changes of regional land use, water resources, and atmospheric environment. This paper analyzes the development status of the current situation of urbanization and ecological environment in Shijiazhuang city and discusses the effect of stress on the ecological environment of Shijiazhuang city: urbanization stress effect on the water resources, urbanization stress effect on land resources, and urbanization stress effect on the atmospheric environment. Keywords-Shijiazhuang city; urbanization; ecological environment; stress effect
Empathic, expressive, advanced virtual coach to improve independent healthy-life-years of the elderly

The EMPATHIC Research & Innovation project will research, innovate, explore and validate new paradigms and platforms, laying the foundation for future generations of Personalised Virtual Coaches to assist elderly people living independently at and around their home. 
Innovative multimodal face analytics, adaptive spoken dialogue systems and natural language interfaces are part of what the project will research and innovate, in order to help dependent aging persons and their carers. 
The project will use remote non-intrusive technologies to extract physiological markers of emotional states in real-time for online adaptive responses of the coach, and advance holistic modelling of behavioural, computational, physical and social aspects of a personalised expressive virtual coach. It will develop causal models of coach-user interactional exchanges that engage elders in emotionally believable interactions keeping off loneliness, sustaining health status, enhancing quality of life and simplifying access to future telecare services.
The project will include a demonstration and validation phase with clearly-defined realistic use cases. It will focus on evidence-based, user-validated research and integration of intelligent user and context sensing methods through voice, eye and facial analysis, intelligent heuristics (complex interaction, user intention detection, distraction estimation, system decision), visual and spoken dialogue system, and system reaction capabilities.
Through measurable end-user validation, to be performed in 3 different countries (Spain, Norway and France) with 3 distinct languages and cultures (plus English for R&D), the proposed methods and solutions will ensure usefulness, reliability, flexibility and robustness.
The project partners include health-maintenance end-user organisations, technology developers, academic / research institutes and system integrators.
The project, planned for a 36-month duration, is estimated to require total funding of 4 M€
Neurocognitive effects following an overnight call shift on faculty anesthesiologists

The impact of sleep deprivation on neurocognitive performance is a significant concern to both the health of patients and to the physicians caring for them, as demonstrated by the Accreditation Council for Graduate Medical Education enforced resident work hours. This study examined the effects of an overnight call at a level 1 trauma hospital on neurocognitive performance of faculty anesthesiologists.Eleven faculty anesthesiologists completed a series of computerized tests that were designed to evaluate different areas of neurocognition, such as working memory, verbal learning, and concentration. The anesthesiologists completed the tests following an overnight call in the morning at 6:30 and again following a normal night's rest at 6:30 on a different date.Within-subjects, repeated measures analysis of variance revealed a significant difference on post-call vs. control performance on measures of learning and memory (P = 0.04). However, there were no significant differences on performance on measures of working memory or sustained attention and vigilance. Pre-call vs. control performances were also evaluated, but no significant differences were detected.Following a night call shift, performance on learning and memory was significantly reduced. Other areas were not significantly affected, which may have been due to certain possibilities, such as practice effect or variability in the call shifts. The real-world relevance of the decline in performance on these measures remains unclear.
Low‐latency digit‐serial dual basis multiplier for lightweight cryptosystems

Various cryptosystems, such as elliptic curve and pairing-based cryptosystems, in resource-constrained security applications rely on finite field multiplication. For applications such as these, a digit-serial multiplier has the potential features to achieve a trade-off between space and time complexities. The authors propose an efficient decomposition of the multiplication into four independent sub-multiplication units to facilitate parallel processing, which is additionally facilitated by the systolic structures of the sub-multiplication units. The proposed architecture uses a four-bit scheme to construct a novel processing element, instead of using only one bit as is currently used in similar multipliers. The results of the synthesis show that the proposed digit-serial dual basis multiplier eliminates up to 96% of the critical path delay.
Deaf smart space

Deaf people encounter several major obstacles that prevent them from seamlessly integrating in society and exclude them from many ICT services that a hearing person simply takes for granted. Hence, our trans-disciplinary team of hearing and deaf, started to develop ICT hardware, services and a smartphone App, which enable people with hearing deficiencies to more seamlessly interact with their environment.
While our App is not at TRL 9, we plan to bring our innovations Deaf Smart Space-Home (DSS-Home) and Deaf Smart Space-Places (DSS-Places) to market within SME Instrument Phase 2. Deaf Smart Space-Home (DSS-Home), at TRL 7, provides accessibility in private homes, while Deaf Smart Space-Places (DSS-Places) at TRL 6 provides accessibility in public buildings such as administrative buildings, airports, train stations, hotels, museums, and shopping malls.

According to the World Health Organization, partial hearing loss affects 360 million worldwide and is likely to grow to 1 billion over the next couple of years. This, paired with advanced signal processing and IoT technology becoming cheaper and therefore more accessible to a large share of the population, paves the ground for our open disruptive Deaf Smart Space innovation.

We have 10143 App users from 142 countries, pre-sold 348 DSS-Homes, and have 25 DSS-Places waiting to be installed. Further, a cooperation agreement has been signed with Spain’s leading tele-assistance provider, Atenzia, to roll out DSS service to 100 000 households, while the President of Telefonica, as well as the General Director of the Vodafone Foundation expressed their interest to become DSS roll-out partners.

By the end of 2019, we aim to acquire 3.5%, 0.08% and 0.075% of the addressable hard hearing market in Spain, Europe and the US, respectively. This corresponds to hardware sales of 24.9M €, services charges of 1.3M €, 86 direct jobs created (30 of them for deaf), plus 81 indirect jobs created at our service and production partner.
Accurate calibration of resistance ratios between 1 MΩ and 1 GΩ using series resistors

As shown in high-resistance key comparisons carried out by the Consultative Committee for Electricity and Magnetism (CCEM), Inter-American Metrology System (SIM) and European Association of National Metrology Institutes (EURAMET), the accuracy of 10 MΩ and 1 GΩ resistances depends on ratio values between the reference resistance and unknown resistance and the accuracy of the reference resistance, which is determined with a quantized Hall resistance standard. This paper presents a method for calibrating 10:1 ratios in a high-resistance bridge using series resistors simply and accurately. By applying the 10:1 ratio errors determined using the presented method, the combined relative standard uncertainty for 1 GΩ resistance measurements using a modified Wheatstone bridge was estimated to be on the 1 × 10−6 level. The method was also applied to 1 GΩ resistance measurements using a direct-current comparator resistance bridge. It was found that the 1 GΩ resistances determined by the two bridges agreed within 2.4 × 10−6 Ω/Ω. We expect that the presented method can also be used to calibrate arbitrary resistance ratios.
Sub-micron lateral topography affects endothelial migration by modulation of focal adhesion dynamics

Through the interaction with topographical features, endothelial cells tune their ability to populate target substrates, both in vivo and in vitro. Basal textures interfere with the establishment and maturation of focal adhesions (FAs) thus inducing specific cell-polarization patterns and regulating a plethora of cell activities that govern the overall endothelial function. In this study, we analyze the effect of topographical features on FAs in primary human endothelial cells. Reported data demonstrate a functional link between FA dynamics and cell polarization and spreading on structured substrates presenting variable lateral feature size. Our results reveal that gratings with 2 µm lateral periodicity maximize contact guidance. The effect is linked to the dynamical state of FAs. We argue that these results are readily applicable to the rational design of active surfaces at the interface with the blood stream.
Solid state spark device and exciter circuit using such a device

A solid state spark device that operates as a two terminal spark gap in a CDI exciter of an aircraft ignition system. The device includes a triggering transformer, a triggering circuit, and a control circuit. The triggering circuit is electrically connected to a first coil of the transformer and includes circuit elements connected to supply current to the first coil upon charging of the triggering circuit up to a triggering voltage. This current through the first coil of the triggering transformer induces an output in a second coil of the transformer. The control circuit is electrically connected to the second coil and includes a switch controlled by the output from the second coil. The switch, when activated by the triggering circuit, discharges energy from the exciter into an igniter of the aircraft ignition system.
Weighted least-squares finite elements based on particle imaging velocimetry data

The solution of the Navier-Stokes equations requires that data about the solution is available along the boundary. In some situations, such as particle imaging velocimetry, there is additional data available along a single plane within the domain, and there is a desire to also incorporate this data into the approximate solution of the Navier-Stokes equation. The question that we seek to answer in this paper is whether two-dimensional velocity data containing noise can be incorporated into a full three-dimensional solution of the Navier-Stokes equations in an appropriate and meaningful way. For addressing this problem, we examine the potential of least-squares finite element methods (LSFEM) because of their flexibility in the enforcement of various boundary conditions. Further, by weighting the boundary conditions in a manner that properly reflects the accuracy with which the boundary values are known, we develop the weighted LSFEM. The potential of weighted LSFEM is explored for three different test problems: the first uses randomly generated Gaussian noise to create artificial 'experimental' data in a controlled manner, and the second and third use particle imaging velocimetry data. In all test problems, weighted LSFEM produces accurate results even for cases where there is significant noise in the experimental data.
Incremental Joint POS Tagging and Dependency Parsing in Chinese

We address the problem of joint part-of-speech (POS) tagging and dependency parsing in Chinese. In Chinese, some POS tags are often hard to disambiguate without considering longrange syntactic information. Also, the traditional pipeline approach to POS tagging and dependency parsing may suffer from the problem of error propagation. In this paper, we propose the first incremental approach to the task of joint POS tagging and dependency parsing, which is built upon a shift-reduce parsing framework with dynamic programming. Although the incremental approach encounters difficulties with underspecified POS tags of look-ahead words, we overcome this issue by introducing so-called delayed features. Our joint approach achieved substantial improvements over the pipeline and baseline systems in both POS tagging and dependency parsing task, achieving the new state-of-the-art performance on this joint task.