SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Voyages

The VOYAGES project is the collective effort of 12 partners and the legacy of 15 years of participation in the ERN as a Consortium. Our ambition is to organize events in 14 different French cities (specifically focusing on medium-sized cities, where there are researchers, but science engagement activities are less frequent), sharing the same objectives, activities, approach to popularization, and involving local researchers. Our project is based on an engaging theme: “Voyages” that will help visitors dream and stimulate researchers.
Convinced that the quality of the exchange with researchers is the key factor in enriching and refining the public's vision of research and science in society, we create warm and aesthetic encounters between the public and researchers. Our theme stimulates the creativity of the scenographers and mediators who design playful activities to be shared by researchers and the public (The Researchers’ suitcase, different Strolls, etc.).
On national and international scales, we are designing three online formats that will allow thousands of people to discover field research all over the world, engage in face-to-face dialogue on Zoom and debate with researchers from other countries.
To achieve this “in person” and “online” strategy, the 1,000 researchers involved in the project will be coached and trained by mediators, artists or scenographers. A long-lasting effect on researchers will be one outcome, as ERN is an occasion for them to start a long journey in science engagement.
The French Ministry of Culture will financially support the event for the 4th year, fostering the participation of researchers in social sciences and humanities; the Ministry of Research will also continue its support. One partner is in charge of strategies for reducing the environmental impact of the events. The ERN will let us take a breath of fresh air and formulate questions about the resources and future of the planet. Flight 2021 to Research is now boarding!
Cloning and characterization of Trypanosoma brucei IFT complex B core

The cilium, a protrusion from the cell surface, has recently attracted immense attention due to its importance in cell signaling and its association with a wide range of human disorders. On the structural level, the cilium consists of a ring of nine microtubule doublets along which the bidirectional movement of ciliary building blocks and turnover products takes place. This transport is termed intraflagellar transport (IFT) and is carried out by two distinct multi-subunit protein complexes, IFT complex A and B, which are responsible for retrograde and anterograde transport, respectively. IFT complex B consists of at least 14 different proteins, eight of which are known to form a salt-stable core complex. Our research focuses on the IFT complex B core. The eight IFT genes from Trypanosoma brucei have been cloned into 4 Duet vectors (Novagen) to enable a simultaneous co-expression of the core complex. Upon co-expression in E. coli, the complex has been purified with minor impurities using Zinc-NTA affinity and size-exclusion chromatography. Six of the eight proteins have been confirmed via mass spectrometry and Western blot. On size-exclusion chromatography, different oligomeric states of the complex can be observed, ranging from >8MDa to around 600 kDa. Preliminary data suggests a liposome-binding capability of the complex, but the responsible subunit(s) remains to be elucidated. Since crystallization of the purified complex has not been successful, future studies will focus on electron microscopy analysis of the recombinant IFT complex B core.
OP61 Perceived maternal stress and emotional wellbeing as risk factors for miscarriage

Background Miscarriage is the most common adverse outcome in pregnancy. Investigations suggest numerous risk factors however the cause remains poorly understood. The study aimed to examine the contribution of an array of psychological factors to risk of miscarriage. Methods A cohort study was conducted in a large, tertiary hospital (8500 deliveries per annum) in the Republic of Ireland in 2012. Women randomly selected at their first booking visit (10–14 weeks) were asked to complete a detailed lifestyle questionnaire, which included common risk factors for miscarriage. Emotional wellbeing, social support, life orientation and perceived stress were assessed using the following validated psychometric tests; the RAND 36-Item Health Survey, the Maternity Social Support Scale, the Revised Life Orientation Test and the Perceived Stress Scale. All participants were followed up at 20 weeks gestation to determine pregnancy outcome. Logistic regression was conducted to assess associations with risk of miscarriage. Results Of the 417 participants, 32.1% (n = 134) had a confirmed miscarriage at follow-up. After adjustment, women with high levels of perceived stress had increased odds of miscarriage (OR 1.97, 95% CI 1.14–3.44) relative to women with low perceived stress (44.1% vs. 26.0%). While high emotional wellbeing was somewhat protective (OR 0.68, 95% CI 0.38–1.11) relative to women with low emotional wellbeing (26.8% vs. 35.9%). Maternal social support and life orientation were not associated with miscarriage. Conclusion Perceived stress and low emotional wellbeing may increase risk of miscarriage. Early assessment and greater support to vulnerable women may be important and warrants further investigation.
Precision farming of hazelnut orchards

The goal of PANtHEOn is to develop the agricultural equivalent of an industrial Supervisory Control And Data Acquisition (SCADA) system to be used for the precision farming of large orchards of hazelnut (Corylus avellana L.). By taking advantage of the technological advancements in the fields of robotics, remote sensing and big-data management, our objective is to design an integrated system where a relatively limited number of heterogeneous unmanned robotics components (including terrestrial and aerial robots) move within the orchards to collect data and perform some of the most common farming operations. The information will be stored in a central operative unit that will integrate the data coming from the different robotic units to perform automatic feedback actions (e.g. to regulate the irrigation system) and to support the decisions of agronomists and farmers. 
We expect that the proposed SCADA system will be able to acquire information at the resolution of the single plant. This will permit to drastically increase the detection of possible limiting factors for each individual plant, such as lack of water or pests and diseases affecting the plant health, and to react accordingly. Compared to the current state of the art in precision farming, we believe that the proposed SCADA infrastructure represents a relevant step ahead in the context of orchards management. In fact, the capability of monitoring the state and the evolution of each single tree will be the enabling-technology to allow more focused interventions. This will result in a better average state of health of the orchard, and in an increased effectiveness of Integrated Pest Managements (IPM). In conclusion, the main advantages of this architecture are:
• Increase in hazelnut productions
• Decrease in chemical inputs usage
• Environmentally-friendly water usage
• Simplified orchard management
The outcome of the project will be validated through a final demo on a real-world (1:1 scale) hazelnut orchard.
Empirical Evidence and Determinants of Region-Based Environmental Injustice in China: Does Environmental Public Service Level Make a Difference?*

Objective

We examine empirical evidence of region-based environmental injustice in China, and factors, especially environmental public service, that contribute to the distribution of environmental hazards among various Chinese regions.



Methods

We use variance analysis to assess the disparate distribution of environmental hazards, and then employ the expanded Stochastic Impacts by Regression on Population, Affluence, and Technology (STIRPAT) model to identify the determinants, using a panel data set of 26 provincial capital cities and four municipalities directly under Chinese central government over the period 2003–2010.



Results and Conclusions

Our findings confirm the presence of region-based environmental injustice in China and demonstrate its annual improvement. We also find that environmental public service, economic development level, population size, and environmental protection technology are major impact factors. These findings not only support the environmental Kuznets curve assumption, but also help to advance the existing literature on environmental justice and the human-environment relationship.
Validation of human papilloma virus assays on self-collected first void urine samples

Annually, about 13,000 women in the EU28 and 266,000 worldwide decease of cervical cancer caused by the human papilloma virus (HPV), thereby ranking third most common cancer worldwide . Throughout Europe, cervical screening programs are organized by local governments to detect cervical cancer at an early stage. Importantly, HPV-based screening (instead of cytology-based screening) is being implemented worldwide. However, a global challenge is that about 40% of women in the EU do not participate in these screening programs and are thus at-risk for development of cervical cancer. To reach these non-attendees, home self-sampling devices can increase the participation rate. The innovative Colli-PeeTM device developed by Novosanis offers a non-invasive, user-friendly solution. The device is suited for collection of first void urine (first 20ml of the urine flow) which allows for detection of HPV DNA. The Colli-PeeTM device thereby offers a novel innovative approach towards HPV-based screening.

The VALPAS (VALidation of human PApilloma virus assays on Self-collected first void urine samples) project aims to successfully launch the Colli-Pee first void urine collection for HPV DNA testing in the EU28 and global market. The feasibility assessment in phase I aims to explore strategies with regard to market penetration & growth, competitors, pricing & reimbursement, partnerships, revenue models; ultimately leading to a business plan for Colli-PeeTM-based HPV screening. Specifically, phase I entails: 

- Market segment analysis
- Competitor bench marking
- Initiation of partnerships with diagnostic companies & labs
- Exploration of pricing & reimbursement strategy
- Assessment of diagnostic assays for analysis for HPV in urine

Phase II funding will be requested to further validate the HPV assays for detection of HPV DNA in first void urine and set-up full scale production and exploitation strategy in the EU28 and at global level.
Self Care of Menopausal Women in Phrae Province. (การดูแลอนามัยของสตรีวัยหลังเจริญพันธุ์ในจังหวัดแพร่)

The objectives of this survery research were to study a health status, menopausal syndrome, knowledge, attitude and self care practive and its associated factors of menopausal women. Three hundred and five menopausal women aged 45-59 years were interviewed during December 1998-March 1999. The result revealed that, the average of menopausal age was 47.9 years.Majors symptoms were pain at joints, bones and muscles.The proportion of body mass index of menopausal women, categorized into low, normal, over and obesity were 12.8%, 63.0%, 20.3% and 3.9% respectively. They acquired hypertension, bone and joint pain. Sixty two percent of them had knowledge scores at a moderate level, 57.3% of them scored well in attitude and 67.2% did well in self care. They rarely exercised and drank milk. Both knowledge and attitude could possibly predicted self care practice about 14%. Factors significantly associated with self care were a level of education and occupation (p<0.05). As a result, self care and annual physical examination programs for menopausal women in community centers, should be promoted as an active strategy. Target groups should be illiterate and primary education level farmers and labors. Key words: menopause, self care
ALPS MOBILITY II - Alpine Pearls

ALPS MOBILITY II focusses on transnational and transsectoral co-operation to promote sustainable development in the Alpine Region by providing a combination of transalpine measures for ecotourism and ecomobility. The project centers on an innovative ecotourism and ecomobility package called „Alpine Pearls“, by linking the protection of the ecologically sensitive Alpine Space, the creation of  environmentally sustainable transport for tourism and of new eco-tourism packages in the sense of win-win-strategies. A travel package through the Alps is developed and implemented, establishing a sustainable travel chain to and between the partner regions and villages and pilot activities focussed and based on environmentally sound transport means. The project will be accompanied by a public awareness and marketing campaign and a progress evaluation. Each partner region will fulfill transnationally defined sustainable mobility and tourism standards, the  so-called „Alpine Pearls“-criteria.
POLITIQUES D’INTÉGRATION SCOLAIRE DANS UNE SOCIÉTÉ MULTICULTURELLE

LA PROPOSITION DE PROJET S’INSCRIT DANS LE DOMAINE DE L’INNOVATION EN MATIÈRE DE TIC ET DE L’INNOVATION TERTIAIRE ET EST COHÉRENTE AVEC LA TRAJECTOIRE TECHNOLOGIQUE CONSACRÉE AUX ÉCOSYSTÈMES NUMÉRIQUES QUI, DANS CE CAS, SONT ORIENTÉES VERS LA PROMOTION DE L’INCLUSION EN COMBINANT DE NOUVEAUX MODÈLES DE SERVICES.
Consortium for Assistive Solutions Adoption

Today, regions and governments are faced with an unsustainable situation with increasing pressure on health and social care resulting from demographic changes. With an ageing population, citizens are also increasingly living with chronic diseases and this has serious implications on the future provision of welfare and health services. Chronic diseases now account for an average of two thirds of healthcare costs in the most advanced countries yet about 80% of such diseases are preventable. A new generation of innovative, secure, wearable, interactive health solutions will have to be developed in regions for the care of the elderly, with personalized information and guidance at home or outdoors i.e. a so-called 'personalized healthcare system'.  The CASA network comprising of 13 participating regions will come together to search for joint-up solutions, access best practices and a policy sounding board through the consortia for the deployment of assistive living solutions (AAL).
The CASA partnership, led by Flanders Ministry of Health will organise 9 study visits on the thematics of 'monitoring, safety and self management', 'social interaction', 'chronic diseases', 'healthy lifestyle and rehabilitation ICT', 'informal care', 'telemedecine evaluation model', 'mobility and liveability/ intregated regional policy, business and knowledge development', 'user driven innovation through public/private partnership',  'large scale deployment' and also 2 Knowledge Transfer Conferences in the New Member States, where neighbouring countries will also be invited. Best practice transfer will culminate in the production of a good practice guide on AAL, 28 staff secondments between organisations to embed good practice. A final conference will take place in Brussels with an award ceremony. Ministerial conferences and relevant PR in all participating regions will be a route to dissemination to wider
stakeholder groups. The proposed partnership approach is innovative on two levels: 1. an attempt for  implementation policies moving away from traditional mono-domain policy to work horizontally along the supply chain and across different departments and ministries and 2. the use of the social media in support of the communication and exchange of knowledges & experiences. After 36 months of implementation, the CASA project will allow the participating organisations to mainstream the learning of the exchange of experiences into their regional strategies. Having proven its relevance, it is intended to formalize and 'legalise' this inter-regional CASA network for long term sustainability and to open it to a wider European platform in the future.
Procoagulant versus anticoagulant factors in cirrhotic patients

Liver cirrhosis leads to decreased production of clotting factors that are generally all produced in the liver except factor VIII and von Willebrand factor. However, cirrhotic patients are not protected from thrombosis. The present study aimed to assess the procoagulant and anticoagulant factors in cirrhotic patients with and without bleeding and/or thrombotic events.A total of 102 adult subjects were enroled: 51 cirrhotic patients and 51 healthy controls. After full history taking with special attention given to thromboembolic and haemorrhagic events, platelet count, serum albumin, bilirubin, international normalised ratio (INR), PT, partial thromboplastin time (PTT), hepatitis B surface antigen (HBsAg), hepatitis B core (HBc) antibodies, hepatitis C virus (HCV) antibodies, factor VIII, protein C, Protac-induced coagulation inhibition percentage (PICI%) assay and abdominal ultrasound were performed for patients and controls. Upper gastrointestinal endoscopy was conducted for the patients.Compared with control subjects, factor VIII and factor VIII/protein C were significantly higher, while protein C and PICI% were significantly lower among patients.Patients with liver cirrhosis may have a tendency for bleeding or thrombosis according to the balance of coagulant and anticoagulant status. PICI%, the assay that evaluated the functionality of the protein C anticoagulant system, was significantly lower in patients compared to control subjects. Accordingly, low PICI% and high factor VIII/protein C ratio can be taken as an index of hypercoagulability in cirrhotic patients.
Iron-Sulphur cluster biogenesis: deciphering new molecular mechanisms and exploiting novel antifungal and fungicide targets

Fungi have major socioeconomic impacts. Recent estimates suggest that invasive human fungal infections kill more than 1.6 million people annually and that 600 million people could be fed each year by halting the spread of fungal diseases in the five most important crops. A range of antifungals/fungicides is currently used to control fungal pathogens in medicine and agriculture, but resistance to those is growing underscoring the urgent need for new molecular targets and treatments. Iron-sulphur (FeS) clusters are inorganic cofactors found in all kingdoms of life and required for several essential cellular processes, such as DNA synthesis, mRNA translation, and respiration. Pathways required for their biogenesis were suggested to represent possible novel antifungal/fungicide targets. The aims of the project are: (1) to identify, via chemical high throughput screening, natural compounds targeting the essential mitochondrial (Arh1-Yah1) and cytoplasmic (Tah18-Dre2) NADPH-dependant electron transfer chains involved in the FeS cluster biogenesis. These compounds could be used in combination with other agents to kill fungal pathogens lowering cost and potential toxicity by reducing doses needed to inhibit fungal growth. (2) To highlight new targets for antifungals/fungicides among the FeS cluster biogenesis and associated pathways. (3) To establish the interaction network of the ferredoxin Yah1 involved in the early steps of the FeS cluster biogenesis knowing that several steps of this process remain poorly understood and new factors may still be discovered. The project will be carried out in the group “Oxidative stress, FeS protein and Cancer” (CNRS-ICSN, Gif-sur-Yvette, France) and will address those objectives by combining my own expertise and that of the host laboratory in microbiology, genetics, biophysics and biochemistry, drug screening and of cutting-edge technologies and approaches such as Förster resonance energy transfer, microfluidics and chemoproteomics.
Cultexp: the first multilingual and cross-jurisdictional database on cultural expertise

Multicultural societies need cultural expertise for solving conflicts. Cultural expertise is to date provided by specialists as specialised and expensive services of expert witnessing and conflict settlement in court and out-of-court. Cultural expertise is not available outside specialised circles of legal professionals. In order to foster the transfer of knowledge about cultural expertise, EURO-EXPERT created CULTEXP as the first multilingual, cross-jurisdictional legal database on cultural expertise. CULTEXP generates an expectation of impact including both societal and economic benefits for the resolution of conflicts and the ascertainment of rights that require cross-cultural knowledge. This PoC will test CULTEXP for its potential of social interest commercialisation. In the present form CULTEXP is a “stripped back” demonstrator holding about 4000 case law and 1000 expert reports from Austria, Belgium, Cyprus, Denmark, Finland, France, Germany, Greece, Italy, India, Malta, the Netherlands, Pakistan, Poland, Portugal, Spain, Sweden and the United Kingdom. CULTEXP’s design is unprecedented for its focus on cultural expertise but also for its architecture which uses ad hoc created or adapted OA software allowing cross-jurisdictional and multilingual search, powered by a combination of human and machine translation. Compared with existing legal databases CULTEXP is extensively more performant because it reaches cross-sectorally most types of legal professions. CULTEXP searches simultaneously across fields of law and languages, provides country specific legal citations, and full texts with translation option; it is free for users, accessible without training, and inexpensive to run. If CULTEXP can be successfully tested, we will establish a start-up with a protect community interest focusing on Open Access, inclusion of non-Anglophone knowledge, inclusion of non-Anglophone users, benefit for disadvantaged social groups, and relief to the taxpayers.
A Review of concepts, characteristics, and guidelines of the supportive design of healing environments

Background Background: Supportive design is a medium of communication for healing environments to maintain and enhance individual’s health from the perspective of user-centered design. This concept is necessary to improve the healing effects of individuals in healthcare design. The aims of this study were to (1) review the concept and characteristics of supportive design and (2) propose guidelines including factors that should be considered for supportive design. Method For this study, previous literature on healing environment, theory of supportive design, and healthcare design were reviewed and analyzed. Results Factors of supportive design, based on the nature distraction design intervention proposed by Cooper Marcus (2007)are categorized by three factors such as human factors (individual needs), spatial factors (physical environment), and behavioral factors (interaction behavior). Guidelines for supportive design, therefore, present three factors and 36 items. Each item reflects users psycho-social, cognitive, functional, and public aspects. Conclusion The guidelines presented in this paper have the following characteristics. First, comfortability enhances the effect of healing by providing a user-friendly environment. Second, positive distraction increases the effect of healing by reducing stress and pain. Third, the role of design intervention is a communication medium in order to connect with healing environments.
Ees innovation csa

The overall aim is to ensure that Scottish SMEs with international innovation and growth ambitions are empowered by unlocking their full growth  potential through better internal innovation management capability.

The underpinning objective of this proposal is therefore to  deliver a quality  service in Scotland that supports SMEs to increase their innovation management capacity and to innovate successfully and profitably.   This requires not only a focused SME targeting strategy, but also qualified staff trained on appropriate tools and methodologies, delivering the right  support to the right SMEs, coordinated with other delivery teams with the Enterprise Europe Network Scotland (EES) host organisations.