SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Geometry of grassmannian lagrangian manifolds and their submanifolds, with applications to nonlinear partial differential equations of physical interest

The aim of GEOGRAL is to strengthen the bonds of the geometric theory of nonlinear PDEs (and, in particular, integrable systems and equations of Monge-Ampère type) with the geometry of  Lagrangian Grassmannians and their submanifolds. In spite of the evident parallelism between these two disciplines, attempts have been rare, yet sophisticated, to cast a bridge between them, and the Applicant himself already gave his own contribution in this direction: he clarified the structure of the space of non-maximal integral elements of the contact planes in jet spaces and studied 3rd order Monge-Ampère equations (which turn out to be of key relevance in topological field theories) through the so-called meta-symplectic structure on the 1st prolongation of a contact manifold.
GEOGRAL has a wide applicative scope, as its theoretical results can be tested on equations and variational problems of key importance for Natural Sciences, Technology and Economy. Tailored to the Applicant's scientific profile and designed in continuity with his previous and current research activities, GEOGRAL consists of four research lines:
[MOV] Regard Lagrangian Grassmannians as homogeneous spaces and and use Cartan's method of moving frame to classify their submanifolds, as in D. The's work, and characterise the corresponding invariant equations, in continuity with D. Alekseevsky's work.
[HYD] Continue the study of certain rational normal curve bundles on Lagrangian Grassmannians, and their bisecant varieties, which are associated with integrable systems of hydrodynamic type, discovered by E. Ferapontov.
[HMA] Geometric study of multi-dimensional and higher-order Monge-Ampère equations, initiated by G. Manno and the Applicant.
[FBV] Study some examples of Cauchy problems and variational problems with free boundary values by exploiting the geometric structures on the spaces of isotropic flags and non-maximal isotropic elements of a meta-symplectic space, in continuity with the Applicant's own work.
Production of potato breads

This study conduct to produce nutritious bread using locally abundant and available raw materials such as wheat, potato, soybean flour &amp; oil. Potato ranks third in Bangladesh behind rice and wheat, in terms of total production. Potato is commonly used as a vegetable in Bangladesh, but in many other areas potato is treated as a staple food. Policy makers and administrators realize that, to meet the country's growing food requirements, the dependence on cereals must be reduced. A bounty production of potatoes in Bangladesh should channelize to product diversification to legitimize the price of Potatoes will help the potato farmers. It is relatively labor-intensive and land-intensive and would combine well with other crops in cropping systems to use land that would otherwise be idle. A sharp revenue earning will be enjoyed for the Government provided potato diversified use occurs here in Bangladesh. This study was dedicated to very high share use of potatoes in various frequently used foods like bread. Trying to use upto 50% of potato to make various products like bread, cakes &amp; potato flakes. The proximate analysis test or laboratory test shows containing protein 2.26% comparing with market breads 1%. The taste of bread produced in our laboratory was compared with other five company wheat breads, available in market. The product showed extraordinary softness &amp; flavor relative to other market available breads. DOI: http://dx.doi.org/10.3329/bjsir.v48i3.17332 Bangladesh J. Sci. Ind. Res. 48(3), 201-204, 2013
Molecular 'click-tronics': surface-based synthesis of single-molecule electronic components

How can single-molecules be best utilized in electronics? Feature sizes of integrated circuits will reach this scale in 10-20 years (Moore’s Law). Typical molecular studies involve surface self-assembled components first synthesised elsewhere (ex situ). Yet surface-based (in situ) preparations offer several distinct synthetic advantages – also simplifying the construction of otherwise difficult to prepare asymmetrical surface-bound motifs.

In this project I will (i) explore unconventional in situ syntheses of single-molecule electronic components, and (ii) develop scanning tunnelling microscopy (STM) techniques to assess the success of chemical reactions at the single-molecule scale. High yielding and versatile (e.g. ‘Click’ ) reactions will prove invaluable in this context. My largely unexplored approach will be used to rapidly screen novel single-molecule diodes and wires, improving rectification ratios and conductance. It will also be applied to produce complex molecular ‘test-beds’, allowing electron transport to be probed through single-molecules orientated parallel to the surface (enabling studies of mechanically weak analytes). This research has broad application and far-reaching impact in data storage and computation (‘wiring-up’ molecules in circuits), and will open up exciting possibilities in sensing and catalysis.

Project results, and nano-science in general, will be actively promoted through a series of Outreach workshops, lectures (implemented in Europe) and a new internet blog, ‘Nanotechnology, Translated’ (contributing to the growing international science blogosphere). A planned secondment to the microelectronics industry will provide commercial and technical insights useful for securing funding and developing future technologies over the next two decades. The new collaborations and enhanced international profile, networks and training provided by this Fellowship will ultimately prove pivotal in helping me establish my independent academic career.
Making a Living, Making a Life: Toward a Spirituality of Work

“Cursed is the ground because of you; in toil you shall eat of it all the days of your life . . . by the sweat of your face you shall eat bread” (Gen 3:17, 19). For many Christians, this biblical image dominates a spirituality of work. We see Adam and Eve standing forlorn outside paradise, exiled for an act of willful disobedience. Now bereft of God’s shining presence, they carry with them a life sentence of hard work, sweat and pain. In this biblical memory, human work is one of the wages of sin. For most of human history, this somber forecast has been well proved. In much of the world even today—including countries sustained by “advanced” economies—work often takes the form of demanding, dangerous, and sometimes degrading physical labor. A spirituality of work developed within the Christian tradition must be accountable to these stark realities. During this century the Catholic Church has addressed these inhumane conditions of work in its social encyclicals and through a range of innovative and sometimes controversial ministries, such as the worker-priest movement in France, Young Catholic Workers and similar associations in many countries. An essential thrust in a Christian spirituality of work has been and must continue to be this intent to promote economic justice and to protect the dignity of workers worldwide. But our brief discussion here moves in a complementary direction. We will examine the experience of work as a potential opening to life in the Spirit. Work reveals us to ourselves—our talents and limits and ambitions. In our first jobs we begin to discover who we are. Even when we enter the employment scene haphazardly—stumbling into our first job or taking the only work available—over time the work that we do helps us craft a durable identity. To the question “who are you?” we answer “I am a nurse” or teacher or manager or electrician. But caught in the vortex of today’s market forces, more and more of us find our work lives recast by false starts, disappointed dreams, and the necessity to start over again. These dynamics challenge earlier self-definitions and raise new questions of meaning.
COMPUTER-IMPLEMENTED SIMULATED INTELLIGENCE CAPABILITIES BY NEUROANATOMICALLY-BASED SYSTEM ARCHITECTURE

Computer-implemented systems for simulated intelligence information processing comprising: a digital processing device comprising an operating system configured to perform executable instructions and a memory; a computer program including instructions executable by the digital processing device to create a hierarchical software architecture comprising: a software module for providing a functional interpretation of the prosencephalon, or parts thereof; a software module for providing a functional interpretation of the mesencephalon, or parts thereof; and a software module for providing a functional interpretation of the rhombencephalon, or parts thereof; wherein the software architecture simulates vertebrate, mammalian, primate, or human neuroanatomy. In some embodiments, the systems create simulated intelligence.
A game theoretic model for coordination of single manufacturer and multiple suppliers with quality variations under uncertain demands

In this paper, a game theoretic model for supply chain coordination problem is studied. The supply chain coordination problem involves one manufacturer and multi-suppliers with quality variations under demand uncertainty. The number of defective parts purchased from suppliers is unknown to the manufacturer while each supplier can determine the standard deviation of defective items. The relationship between the manufacturer and the suppliers is modelled by a non-cooperative game. The non-cooperative game model is analysed by the Stackelberg equilibrium where the manufacturer is regarded as a leader and the suppliers as followers. By deriving suppliers’ best response functions, the Stackelberg equilibrium under uncertainties is established. Sensitivity analysis is conducted to investigate the features of the proposed models with cost parameters. The results validate the derived managerial insights derived for the proposed model.
Diabète de l’enfant, de l’insulino-vers l’immunothérapie: une prise en charge globale du présent vers le futur

Diabetes type I (DTI) is an autoimmune disease characterized by a progressive destruction of the insulin producing beta cells of the pancreas that requires insulin substitution therapy. Recent epidemiological data show an annual increase of the incidence of DTI of 3.9%. Children with new onset diabetes typically present with polyuria, polydipsia and weight loss. As of today no cure for DTI exists. However new therapeutic immunomodulary approaches are under investigation. In the meantime adherence to insulin therapy is mandatory to achieve near physiological glucose levels. Monogenic forms of diabetes remain rare in children, but their diagnosis is important in order to propose a specific treatment. A critical period for the diabetic patient is the transition from pediatric to adult care.
Effects of Introduction Carbon Tax on China's Economy

In recent years,China's carbon dioxide emissions have increased significantly,and aroused wide attention of the whole society.Carbon tax is one of the most effective economic means.Taxing on carbon dioxide at proper opportunity is not only China's response to climate change,energy consumption and emission reduction but also China's response to assuming corresponding international responsibility.According to the Chinese provincial energy consumption and the correlation coefficient of energy products,this paper accounted the carbon dioxide emissions of fossil energy products,then setting three different carbon tax rates according to the accounting data and international practice experience.Using a panel data model and the panel data of China's provinces from 1999-2007,we quantitatively analyzed the impact of carbon tax on economy,especially the effect on economic growth and energy consumption.Research shows that: ① a carbon tax would redue social output and have negative influence on economic growth.In the long run,as the gradual improvement of carbon tax rates and the tax system become perfect,this negative influence will be weakened.② a carbon tax can improve energy output efficiency,reduce the use of energy elements and cut CO2 emissions.③ increasing carbon tax rates will narrow the income distribution gap between labor and capital.Therefore,carbon taxation has obvious effects on energy saving and emission reduction.But under the restriction of China's current economic development level levying tax on carbon dioxide has great impact on Chinese economy,so it's not suitable for taxation in the short term.
Tumor endothelial cells: gatekeepers of anti-tumor immunity

Immunotherapy, in the form of immune checkpoint inhibitors, is the upcoming anti-cancer therapy, but suffers resistance in large fractions of cancer patients (also lung cancer). Tumors stimulate angiogenesis to ensure their supply of nutrients, however much less studied is how tumor endothelial cells (TECs) contribute to immunosuppression. Endothelial cells (ECs) represent a major non-hematopoietic component of immunity and TECs are presumed to be immunosuppressive, in part by expressing elevated levels of PD-L1. However, the role and dynamics of TEC-expressed PD-L1 in anti-tumor immunity relative to the cancer expressed PD-L1 remain incompletely understood.

Given the strategic “1st line” location of TECs, the question raises if at least part of the success of PD-L1 inhibition, is attributable to an effect on TEC immunity. Therefore, for the 1st time, I will fill this gap of knowledge by characterizing mice lacking PD-L1 in ECs and assess tumor progression and anti-tumor immunity in these mice using different tumor models. I will assess the efficacy of anti-PD-L1 blockade in mice lacking PD-L1 in ECs in different stages of tumor growth to delineate the dynamics of PD-L1 expression in TECs. Moreover, by using established in vitro approaches, I will study the effect of PD-L1 knock-down in human lung tumor derived TECs vs. normal ECs on human T cell proliferation, effector function and transmigration. The proposed research provides unprecedented insights in the relative role of tumor endothelial vs. cancer cell-derived PD-L1 in immunosuppression.

This is a multi-disciplinary project at the interface of angiogenesis, immunology and cancer. Combining my expertise on T cell biology with the host’s expertise in angiogenesis and exceptional scientific infrastructure (core facilities) and innovative science (EC:T cell interactions during immunotherapy) will ensure successful achievement of the project goals and provide a highly competitive training for my future career.
Adaptive control of a master-slave system for teleoperated needle insertion under MRI-guidance

This paper presents the control of a master-slave system for teleoperated needle insertion under guidance by Magnetic Resonance Imaging (MRI). The primary aim of our research is the robot-assisted laser ablation of liver tumors. The master-slave system consists of a master unit that sits next to the operator, outside the scanner room, and of a slave unit located inside the cylindrical MRI scanner. The needle insertion force is measured with a specially designed fiber optic force sensor mounted on the slave unit. Pneumatic actuation is employed in both master and slave in order to minimize the interference with the MRI environment. Accurate position control of the slave unit is achieved with a Time Delay Control scheme (TDC). Differently from previous designs, the force feedback on the master unit is provided by an adaptive controller that compensates the friction of the pneumatic actuator. The advantages over a baseline force controller are demonstrated with experiments on silicone rubber phantoms.
RIGID BIOFIBER THERMOPLASTIC COMPOSITE AND ARTICLES MADE THEREFROM

Coated reinforcing biofiber for thermoplastic articles is disclosed. The coating on the biofiber comprises a plastisol. The coated reinforcing biofiber can be used in thermoplastic compounds to simulate the appearance of natural wood while adding significantly increased flexural modulus for the wood plastic composite (WPC).
Adaptation to Saltwater inTrusion in sEa level RIse Scenarios

The project aims, on the basis of a common assessment of spatial and temporal variation in seawater intrusion, at identifying and mapping needs and barriers in risk management and to provide practical tools for a sustainable management through the identification of boundary conditions at a local scale. To this overall objective, the project will provide two main outputs:a map of vulnerability to coastal salinisation at the macro-regional scale (Adriatic) based on future scenarios for sea-level rise and the hydrological cycle and a best practice and guidelines for the management of vulnerable site defined though an analysis of representative case studies in Italy and Croatia.
Biomass low cost advanced zero emission small-to-medium scale integrated gasifier-fuel cell combined heat and power plant

BLAZE aims at developing Low cost, Advanced and Zero Emission first-of-a-kind small-to-medium Biomass CHP. This aim is reached by developing bubbling fluidised bed technology integrating high temperature cleaning & conditioning system (IBFBG, that can convert heterogeneous feedstocks in a syngas with zero particulate matter and ultra-low tar and contaminants content), an integrated high temperature gas cleaning approach for HCl and H2S removal and an innovative key component for thermal and chemical integration of solid oxide fuel cell (efficient gas recirculation of the fuel cell anode exhaust to the gasification process via a steam-driven high speed micro-compressor using gas bearing technology). The technology is developed for a CHP capacity range from small (25-100 kWe) to medium (0.1-5 MWe) scale and is characterised by the widest fuel spectrum applicable (forest, agricultural, industrial and municipal waste also with high moisture, ash and contaminants content), high efficiencies (50% electrical versus the actual 20%), low investment (< 4 k€/kWe) and operation (≈ 0.05 €/kWh) costs as well as almost zero gaseous and PM emissions, projecting electricity production cost below 0.10 €/kWh . Gasification, gas cleaning & conditioning and fuel cells will be tested at lab scale and 25 kWe SOFC will be thermally and chemically integrated in 100 kWth IBFBG demonstrating the achievement of new milestones, increasing competitiveness of European industry, energy system reliability and flexibility and biomass plants social acceptance. Process simulations, computer aided design, tests, performance evaluation, risk and safety analysis as well as a technology assessment part covering techno-economic, environmental and overall impact assessments and market studies will be carried out together with a clear dissemination, exploitation and communication plan, that can count on the involvement of the main gasifier, gas conditioning and SOFC European companies and research centres.
A pilot study of serum microRNA signatures as a novel biomarker for occult hepatitis B virus infection

The implementation of hepatitis B surface antigen (HBsAg) screening tests has significantly enhanced blood transfusion safety. However, the transmission of HBsAg-negative blood components can still occur in the acute phase of infection during the seronegative window period or during chronic stages of infection such as occult hepatitis virus B infection (OBI). OBI, characterized by the presence of HBV infection without detectable HBsAg, is capable to elude the routine detection with HBV serologic markers and harbor a potential risk of HBV transmission through blood transfusion or organ transplantation. Here, we test the hypothesis that OBI patients have a differentially expressed profile of microRNA (miRNA) in serum, and this unique serum miRNA signature can serve as a biomarker to detect OBI. Employing TaqMan probe-based quantitative reverse transcription polymerase chain reaction (qRT-PCR), we assessed the expression level of miRNAs in serum samples. To control for miRNA quantitation, we added an exogenous plant miRNA, MIR156a, into the samples before RNA extraction and used it as an internal control. After screening 13 previously identified HBV-specific serum miRNAs, we obtained four miRNAs, let-7c, miR-23b, miR-122, and miR-150, which are differentially expressed in OBI sera compared to healthy control sera. This 4-serum miRNA signature shows a high level of accuracy in discriminating both OBI (AUC = 0.999) and HBV (AUC = 0.989) cases from the non-infected controls. Cluster analysis also demonstrates that this 4-miRNA signature can clearly separate OBI patients from the control group. Our results demonstrate for the first time that a profile of serum miRNAs can serve as a sensitive and accurate biomarker for OBI detection.
Bootstrap and uniqueness for form factors and the s-matrix

Scattering amplitudes and form factors are fundamentally important quantities in quantum field theories, directly related to physical observables such as probabilities of particle interactions measured in collider experiments. Over the last decades, studies of these objects have revealed beautiful physical and mathematical structures, which have inspired powerful computational methods making accessible previously impossible calculations. The goal of this project is to further uncover such hidden structures, by exploiting a surprising interplay of fundamental principles. One focus will be on recently discovered infrared and ultraviolet principles, their possible duality, and how they can be used to construct scattering amplitudes in new ways that expose unitarity as an emergent property. Next, the project will explore the expression of unitarity as a geometry of positive constraints, which was conjectured to fully define string theory amplitudes. The final main goal is the application of such on-shell principles and the color-kinematic duality to form factors, off-shell generalisations of scattering amplitudes of great phenomenological importance. The project also encompasses a comprehensive program for the dissemination and communication of its results. The former will be based on publications in high impact journals and talks at major conferences, while the latter involves diverse outreach activities targeted at a wide range of audiences. The researcher will benefit from a bespoke training program, including courses in career management, public engagement, teaching activities, and participation in scientific workshops. The balanced distribution of these complementary activities is designed to optimise the benefit for the researcher, to increase his visibility and independence, to enhance his skills portfolio and, hence, to prepare him for a permanent academic position in the future.