SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Bridging the evolutionary gap between unicellular endosymbiotic cyanobacteria and organelles

Symbiosis has been key to evolution on Earth. The success of eukaryotes was possible due to the establishment of endosymbiotic relationships between unicellular microorganisms that gave rise to specialized organelles (chloroplasts and mitochondria), yet the mechanisms underpinning such biological innovations are still unresolved. An unusual marine nitrogen-fixing symbiosis involving a cyanobacterium called UCYN-A and a single-celled haptophyte algae (Braarudosphaera bigelowii) was recently found to have undergone genome rearrangements analogous to organelle evolution. Since no eukaryotes fix nitrogen (N2), an essential nutrient for life, knowledge on this peculiar symbiosis may serve as a unique opportunity for understanding the acquisition of new organelle-derived functions in eukaryotes. The UCYNELLE project is designed to provide new insights on organelle evolution through the multidisciplinary study of the UCYN-A symbiosis from an ecological, evolutionary and metabolic perspective: First, experimental manipulations with the UCYN-A culture and field surveys will be conducted to identify the molecular basis regulating the metabolic coupling between symbiotic partners and the associated microbiome. Second, the organelle genomes of the haptophyte host will be compared to those of the different UCYN-A lineages via comparative genomics to explore any parallelisms in their mode of evolution. Finally, the natural variation in cell size shown by UCYN-A and its host across different UCYN-A symbioses will allow investigating the metabolic scaling (metabolic rates vs cell size) of the N2 fixation process compared to that of typical organelle-driven metabolisms (photosynthesis and respiration) through the study of the volumetric relationships between chloroplasts, mitochondria, UCYN-A and its host. Elucidating the mechanism underlying the UCYN-A symbiosis will help to understand the early evolutionary steps leading to the acquisition of plastids in eukaryotes.
Cyclone furnace for hazardous waste incineration and ash vitrification

An apparatus and method for vitrifying inorganic hazardous material including heavy metals from waste containing organic and inorganic substances. The inorganic hazardous material is retained and vitrified in the slag layer of a cyclone furnace where it is converted to a nonleachable, inert form for safe disposal in conventional landfills and where, simultaneously, organic hazardous substances are completely destroyed.
O lugar do Sistema Mineiro de Avaliação da Educação Pública (Simave) na busca pela qualidade da educação no Brasil

The Mining System for Evaluation of Public Education (Simave), responsible for the development of integrated assessment of education in the state of Minas Gerais, emerges in the wake of implementation of regulatory policy of education in Brazil. This policy, in turn, is part of the reform movement of educational policies in the context of capitalist restructuring process. The purpose of this paper is to question its place in this system of evaluation in brazilian regulatory policy. With this objective, to weave accounts of its principles, goals and ways of operation. By analyzing historical and politically Simave, one may question its guidelines, based on the discussion of political and administrative reforms inLatin America. These reforms are linked to the entry of international organizations in the financing of national and local educational projects. The text points out the contradictions within the system and aspects of policy Simave subject to further discussion, such as the relationship between the principles underlying the system of assessment and prioritized strategies to improve the quality of education in Minas Gerais
Network Analysis of Inflammatory Genes and Their Transcriptional Regulators in Coronary Artery Disease

Network analysis is a novel method to understand the complex pathogenesis of inflammation-driven atherosclerosis. Using this approach, we attempted to identify key inflammatory genes and their core transcriptional regulators in coronary artery disease (CAD). Initially, we obtained 124 candidate genes associated with inflammation and CAD using Polysearch and CADgene database for which protein-protein interaction network was generated using STRING 9.0 (Search Tool for the Retrieval of Interacting Genes) and visualized using Cytoscape v 2.8.3. Based on betweenness centrality (BC) and node degree as key topological parameters, we identified interleukin-6 (IL-6), vascular endothelial growth factor A (VEGFA), interleukin-1 beta (IL-1B), tumor necrosis factor (TNF) and prostaglandin-endoperoxide synthase 2 (PTGS2) as hub nodes. The backbone network constructed with these five hub genes showed 111 nodes connected via 348 edges, with IL-6 having the largest degree and highest BC. Nuclear factor kappa B1 (NFKB1), signal transducer and activator of transcription 3 (STAT3) and JUN were identified as the three core transcription factors from the regulatory network derived using MatInspector. For the purpose of validation of the hub genes, 97 test networks were constructed, which revealed the accuracy of the backbone network to be 0.7763 while the frequency of the hub nodes remained largely unaltered. Pathway enrichment analysis with ClueGO, KEGG and REACTOME showed significant enrichment of six validated CAD pathways - smooth muscle cell proliferation, acute-phase response, calcidiol 1-monooxygenase activity, toll-like receptor signaling, NOD-like receptor signaling and adipocytokine signaling pathways. Experimental verification of the above findings in 64 cases and 64 controls showed increased expression of the five candidate genes and the three transcription factors in the cases relative to the controls (p<0.05). Thus, analysis of complex networks aid in the prioritization of genes and their transcriptional regulators in complex diseases.
A quantitative, multifunctional, non-invasive and cost-effective food freshness indicator to reduce food waste

Every year more than one 1.3 billion tons of food are wasted which is a huge both environmental and economic problem. Food waste happens all along the pathway to the plate and is a massive food supply chain inefficiency. For example inefficiencies occur when the fresh food manufacturers perform destructive quality controls every hour to detect leaks in the packaging, or when the cold chain breaks occur during transit, or when consumer fights against uncertainty by throwing away food. The expiry date is fixed during the packaging through studies of life-time and causes all agents in the food supply chain to lose money and waste resources at some point. Currently, the traceability tools available in the market do not offer information on the real state of freshness and quality of food products. 
ColorSensing is based on an advanced algorithm able to correct color distorsions of QR codes made of smart inks for sensing parameters inside food packages. Integrating this with digital solutions allows to monitor the freshness of packaged foods and extend their shelf life. Our innovative technology (TRL6) is a quantitative, multifunctional, cost-effective and non-invasive food freshness indicator to reduce food waste. We have received public funds to develop our technology (e.g. €1.5m from the EU ERC program) and been selected to participate in multiple startups accelerator programs such as ENPENTA VII or Innofood. We have created an ecosystem of industrial partners (food manufacturers as Embutits Monells, Barrufet Group and supermarkets as Bonpreu and Condis) that are interested in our technology and are asking us to develop our prototypes up to a market-ready solution. We aim to become the next quality standard in packaged food manufacturing and now we are applying to the SME Instrument Phase 1 to carry out an exhaustive Feasibility Study.
AIB1, A NOVEL STEROID RECEPTOR CO-ACTIVATOR

The invention features a substantially pure DNA which includes a sequence encoding a novel steroid receptor co-activator which is overexpressed in breast cancer cells, diagnostic assays for steroid hormone-responsive cancers, and screening assays to identify compounds which inhibit an interaction of the co-activator with the steroid hormone.
In vivo metabolism of chemical constituents of traditional Chinese Materia Medica: research and discussion

Traditional Chinese Materia Medica (TCMM) has a long history for its application in treating diseases, and has been proved in clinic for its efficacies. In the most cases, these medicines are taken orally, and the oral bioavailabilities of their chemical constituents are generally poor, and one of the most important causes is that the chemical constituents are biotransformed in gastrointestinal tract or in liver due to the in vivo chemical and biological circumstances. Since the pharmacological effects are considered to be derived from the absorbed chemical substances, we believe some biotransformed products might play an important role for the effectiveness of TCMM. Although the study on chemical constituents of TCMM has made significant achievements in the past three decades, the study on in vivo metabolism of TCMM constituents has still been in slow progress. In order to promote the research progress in this field, this paper will give some suggestions and ideas based on the current research situation, and some examples are presented to reveal the role of in vivo metabolism of chemical constituents in clarifying effective substance of TCMM.
On the impact of disproportional samples in credit scoring models: An application to a Brazilian bank data

Statistical methods have been widely employed to assess the capabilities of credit scoring classification models in order to reduce the risk of wrong decisions when granting credit facilities to clients. The predictive quality of a classification model can be evaluated based on measures such as sensitivity, specificity, predictive values, accuracy, correlation coefficients and information theoretical measures, such as relative entropy and mutual information. In this paper we analyze the performance of a naive logistic regression model (Hosmer & Lemeshow, 1989) and a logistic regression with state-dependent sample selection model (Cramer, 2004) applied to simulated data. Also, as a case study, the methodology is illustrated on a data set extracted from a Brazilian bank portfolio. Our simulation results so far revealed that there is no statistically significant difference in terms of predictive capacity between the naive logistic regression models and the logistic regression with state-dependent sample selection models. However, there is strong difference between the distributions of the estimated default probabilities from these two statistical modeling techniques, with the naive logistic regression models always underestimating such probabilities, particularly in the presence of balanced samples.
ManuFactUring educaTion and training governance model for IndUstry 4.0 in the Adriatic-Ionian aREa

The challenges brought about by the fourth industrial revolution are at the very heart of the project FUTURE 4.0. The further developmental stage in the organisation and management of the entire value chain process involved in manufacturing industry is radically changing even the concept of enterprise. EUSAIR area societies and economies are affected as well by this paradigm shift, which has effects on production, intercompany relations, human capital development. To face this, and having as specific focus Blue Economy, the shipyard & nautical logistic supply chain, the project intends to design a shared strategy to innovate companies approach to training through a Smart Learning Model enhancing shipyard competitiveness in Italy (Veneto & Apulia), Croatia, Greece and Albania. The project structure foresees the definition of a Technological Map of the Shipyard & Nautical Logistic supply chain thorough inclusive road mapping and foresight activity on technology and related competences. Results will be the lay for the designing of a knowledge, competence and skills training/learning hub (FUTURE4.0 platform) involving Universities and training orgs., companies and PAs. _x000D_
The platform will be part of the above-mentioned Smart Learning Model and Strategy, implemented and validated through local pilot actions, encompasses effective industrial education and training for innovation, enhancing the University-Industry cooperation. The partnership is multi actor and includes public and private bodies, universities, business supp. orgs., HE institutions active in Industry 4.0 which will cooperate together applying a Triple Helix approach. Accordingly, the project will impact on current situation stimulating a common and participatory rethinking of regional governance systems for training and innovation support towards Industry 4.0, specific for the shipyard & nautical logistic supply chain. Mutually cooperating 4 universities, PAs, business actors (Large Companies, SMEs, KIBs, Business Supp. orgs.) and R&I players will define a sectoral technological roadmap and foresight as basis for the subsequent development of a share Training Model, tested and validated through its application at each local context. FUTURE 4.0 will see the involvement of 105 companies (primary target group and beneficiaries along with PAs) of the Blue Economy in a knowledge and technology transfer tailored process, along with the production of tools and methods to facilitate a smart industrial change. Results are addressed at Adriatic-Ionian companies, human capital developers, public administrations and knowledge providers. Involved regions share the same challenges, as they face the same transformations and their productive systems should be more integrated. That is why the project should be realized transnationally. What is original is the combination of model design, learning actions, local action plans, profiles upskilling, within a topic - Industry 4.0 - which is brand new.
FOLDABLE BICYCLE

A folding bicycle comprises a steerable front wheel (1) assembly including a front frame member (4) and a rear wheel (2) assembly including a lower frame member, a seat post member and a rear wheel, the lower frame member (3) comprising a first hinge connected to the seat post member (7) and operating on a horizontal axis to allow the bicycle to be folded, the steerable front wheel assembly comprising a hinged handlebar (30) operable in use to position the handlebar in contact with the rear wheel, thereby reducing the size of the bicycle.
Towards an Intelligent Code Search Engine

Software developers increasingly rely on information from the Web, such as documents or code examples on Application Programming Interfaces (APIs), to facilitate their development processes. However, API documents often do not include enough information for developers to fully understand the API usages, while searching for good code examples requires non-trivial efforts. To address this problem, we propose a novel code search engine, combining the strength of browsing documents and searching for code examples, by returning documents embedded with high-quality code example summaries mined from the Web. Our evaluation results show that our approach provides code examples with high precision and boosts programmer productivity.
APPARATUS AND METHOD FOR RECOVERY OF MARINE STRUCTURES

For the recovery of an underwater structure (1) of tubular form, such as a jacket of a decommissioned oil rig, a lifting attachment (10) is inserted into a free end (2) of a tubular member of the structure (1), and is then plastically deformed by hydraulic forming so that it engages mechanically and securely with the inside of the tubular member, which is at least elastically deformed. The structure (1) can then be recovered to the surface by means of recovery cables (45) attached to a lug (14) on the lifting attachment (10). This saves having to weld attachments to the structure.
LOC PRO II-Support and Promotion of Local Products and SMEs through ICT

LOC PRO II project is the continuation of the successful LOC PRO I project, which was completed under the previous “GR-IT” INTERREG program. The main objective concerns the support of entrepreneurs & enterprises producing local typical quality products, in such a manner that achieves a high degree of ICT integration in the everyday work and the use of modern marketing tools & techniques. This aim will be achieved through the following outcomes: • Development of an enhanced ICT platform. • Development of a distance e - learning platform. • Development of an on-line database with joint market & supply chain researches. • Production of optimal biological guides for the local typical products. • Skill building and knowledge transfer seminars. • Workshops and participation in exhibitions. • The design and pilot operation of Regional Information Communication & Technology Centers (R.I.C.T.s)
WALKER TOY

The inventive toy is embodied in the form of a figurine moving downwards along an inclined plane. Said toy resembles an ordinary Chinese tumbler and consists of a light body, a load arranged in the lower part thereof and a base (outsole) having a special shape. Said outsole is embodied in the form of a convex variable curved surface. When said figurine is placed on the inclined plane and rocked from side to side, it starts to move rocking downward along said inclined plane.
SCALE TO CONSOLIDATE: NEW BOULDER ROOM AND EQUIPMENT INCREASE

FITNESS FACTORY SRL SINCE 2016 DEALS WITH PHYSICAL, GYMNASIUM AND SPORTS ACTIVITIES AT ITS GYM LOCATED IN PRATA CAMPORTACCIO (SO).PRESSO THE OPERATIONAL HEADQUARTERS, COMPOSED OF DIFFERENT MULTIFUNCTIONAL AREAS, CUSTOMERS CAN TAKE ADVANTAGE OF THE NUMEROUS EQUIPMENT PROVIDED AT THEIR DISPOSAL IN ADDITION TO ADVICE AND SUPPORT OF QUALIFIED PERSONNEL, BESIDES ARE ORGANISED SPECIFIC COURSES DEDICATED TO FITNESS, SUCH AS ZUMBA, WHUSU, YOGA, PILATES WITH THE COLLABORATION OF EXTERNAL PROFESSIONALS, BUT ALSO BOXING COURSES AND KICK BOXING.THE PROJECT PRESENTED FORESEES THE ACQUISITION OF A BOULDER WALL FOR CLIMBING LACTIVITY, CHARACTERISED BY 2,000 GRIP POINTS AND 30 DIFFERENT VOLUMES, IN ADDITION IT WILL END WITH LÂAMPLIAMENTO DELLOFFERTA IN TERMS OF MACHINERY AND EQUIPMENT FOR CARDIO, CROSS-FIT AND ISOTONIC AND GINNASTICA TRAINING.THE EXPECTED RESULT RESULTING FROM THESE INTERVENTIONS WILL GUARANTEE A GROWTH IN TERMS OF CUSTOMER FLOW, DETER
Soft milli-robots

SOMIRO
Precision agriculture for rice farming and smart methods such as aquaponics are vital to ensure a safe supply of fresh food for Europe while reducing our environmental footprint. In line with the Digitising European Industry initiative under their description of smart agriculture, the SOMIRO project will develop a flat-worm-inspired mm-scale swimming robot with month-long energy autonomy, local intelligence, and ability to continuously generate data and optically communicate to reduce farming’s environmental impact in terms of carbon footprint, over fertilization, pesticide use, and overfeeding. Swimming robots would cover a much larger area than stationary systems and could be rapidly deployed and self-redistribute where most needed. They may serve as a stand-alone monitoring solution for indoor farming or complement drone-based remote sensing in outdoors scenarios.
Until today, no energy autonomous (untethered and with local intelligence) milli-robot capable of hours of continuous operation has been demonstrated. The major reason for this is power limitation: locomotion requires much power and small robots have very limited energy storage and energy harvesting. Our milli-robot will be less than 1 cm long and show how soft and stretchable systems, with undulating swimming like flat worms, require far less energy for locomotion than other systems of comparable size. For power, it will not rely on any dedicated infrastructure but only on ambient light.
The design of SOMIRO focuses on its industry transfer: industrial partners will use cutting-edge assembly technologies that can scale up to production volumes with no change in process. The bulk materials are low-cost elastomers and polymers and the electronic circuits will be based on commercial components. Throughout the project, all application scenarios and exploitation plans will be developed in close collaboration among the SOMIRO partner enterprises and end-users, and external industrial stakeholders.
Avoid major disasters by welcoming minor change

What can a 70-year-old book on how to play bridge tell us about addressing the ongoing refugee crisis in Europe? And what does it have to do with King Lear? In Shakespeare's play, the Duke of Albany warns that “striving to better, oft we mar what's well”. In the search for a solution, in other words, we can let the perfect become the enemy of the good. In his 1945 book Why You Lose at Bridge, S. J. Simon called it the half-loaf strategy: the most successful players aim for the best possible result, rather than the best result possible. In human and political crises, the best possible result is often one of damage limitation — an outcome that avoids or delays the chance of a large-scale and catastrophic change. So, the question then becomes: how can we achieve such an outcome? Language: en
LATERAL SEISMIC BRACE

A sway brace fitting clamp is used for lateral bracing of sprinkler or other types of pipe (designated the service pipe) to a structure, to prevent movement of the service pipe perpendicular to the axis of the pipe relative to the structure to which it is attached. The sway brace fitting clamp includes a U-bolt which fits around the service pipe, and a pair of hooks that are coupled to straight ends of the U-bolt, for hooking the sway brace pipe. A pair of nuts engages threaded portions of the U-bolt ends. The nuts may be tightened to pull the sway brace pipe into contact with the service pipe, firmly clamping the sway brace pipe and the service pipe together.
In vitro antibiotic resistance of Vibrio-like organisms isolated from seawater and sand of marine recreation beach in the southern Baltic Sea

Vibrio-like bacteria (VLO) were isolated from the seawater and sand of marine recreation beach located on the southern coast of the Baltic Sea and their antibiotic resistance was studied. According to susceptibility test, planktonic, and benthic VLO were the most resistant to β-lactam (ampicillin and penicillin) and lincosamide (clindamycin) antibiotics, while the most susceptible to tetracycline and aminoglycosides (gentamycin). Moreover the results showed that Vibrio-like bacteria inhabiting sand were more antibiotic-resistant than those isolated from seawater. In general, there was no difference in antibiotic resistance between VLO isolated from the surface and subsurface sand layers. More than 90% of planktonic and benthic Vibrio-like bacteria showed multiple antibiotic resistance.