SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Virtual Power Systems as an Instrument to Promote Transnational Cooperation and Sustainable Energy Supply in the Alpine Space

At present, the Alpine Space is characterised by strong territorial discrepancies with regard to (conventional) energy supply. Rich endogenous renewable energy sources (RES) like hydropower, solar and wind energy, wood and other biomass exist throughout the Alpine Space, but equal access to their use is even more restricted because the need to balance electricity production and use requires a strong electric grid and its – often unacceptable - extension or strengthening if the rate of RES is to be increased.
Virtual Power Systems (VPS) offer an alternative by using ICT-technology for intelligent combinations of RES, load management and storage. A prerequisite are innovative ways of cooperation among utilities, independent power producers and consumers. VPS have a high potential to trigger new knowledge-based and competitive economic activities. AlpEnergy will explore this potential and sensitise political and business decision makers. This includes a comprehensive communication concept.
Lipid Clustering Correlates with Membrane Curvature as Revealed by Molecular Simulations of Complex Lipid Bilayers

Cell membranes are complex multicomponent systems, which are highly heterogeneous in the lipid distribution and composition. To date, most molecular simulations have focussed on relatively simple lipid compositions, helping to inform our understanding of in vitro experimental studies. Here we describe on simulations of complex asymmetric plasma membrane model, which contains seven different lipids species including the glycolipid GM3 in the outer leaflet and the anionic lipid, phosphatidylinositol 4,5-bisphophate (PIP2), in the inner leaflet. Plasma membrane models consisting of 1500 lipids and resembling the in vivo composition were constructed and simulations were run for 5 µs. In these simulations the most striking feature was the formation of nano-clusters of GM3 within the outer leaflet. In simulations of protein interactions within a plasma membrane model, GM3, PIP2, and cholesterol all formed favorable interactions with the model α-helical protein. A larger scale simulation of a model plasma membrane containing 6000 lipid molecules revealed correlations between curvature of the bilayer surface and clustering of lipid molecules. In particular, the concave (when viewed from the extracellular side) regions of the bilayer surface were locally enriched in GM3. In summary, these simulations explore the nanoscale dynamics of model bilayers which mimic the in vivo lipid composition of mammalian plasma membranes, revealing emergent nanoscale membrane organization which may be coupled both to fluctuations in local membrane geometry and to interactions with proteins.
MPSoCBench: A toolset for MPSoC system level evaluation

Recent design methodologies and tools aim at enhancing the design productivity by providing a software development platform before defining the final MPSoC architecture details. However, the simulation can only be efficiently performed when using a modeling and simulation engine that supports the system behavior description in a high abstraction level. The lack of MPSoC virtual platform prototyping integrating both scalable hardware and software in order to create and evaluate new methodologies and tools motivated us to develop MPSoCBench. This toolset is a scalable set of MPSoCs including four different ISAs (PowerPC, MIPS, SPARC, and ARM) organized in platforms with 1, 2, 4, 8, 16, 32, or 64 cores, cross-compilers, IPs, interconnections, and 17 parallel version of software from well-known benchmarks. This tool also provides power consumption estimation for MIPS and SPARC processors. The MPSoCBench sums 864 different configurations automated through scripts.
Transient infrared absorption of t-CH3C(O)OO, c-CH3C(O)OO, and α-lactone recorded in gaseous reactions of CH3CO and O2

A step-scan Fourier-transform infrared spectrometer coupled with a multipass absorption cell was utilized to monitor the transient species produced in gaseous reactions of CH(3)CO and O(2); IR absorption spectra of CH(3)C(O)OO and alpha-lactone were observed. Absorption bands with origins at 1851+/-1, 1372+/-2, 1169+/-6, and 1102+/-3 cm(-1) are attributed to t-CH(3)C(O)OO, and those at 1862+/-3, 1142+/-4, and 1078+/-6 cm(-1) are assigned to c-CH(3)C(O)OO. A weak band near 1960 cm(-1) is assigned to alpha-lactone, cyc-CH(2)C(=O)O, a coproduct of OH. These observed rotational contours agree satisfactorily with simulated bands based on predicted rotational parameters and dipole derivatives, and observed vibrational wavenumbers agree with harmonic vibrational wavenumbers predicted with B3LYP/aug-cc-pVDZ density-functional theory. The observed relative intensities indicate that t-CH(3)C(O)OO is more stable than c-CH(3)C(O)OO by 3+/-2 kJ mol(-1). Based on these observations, the branching ratio for the OH+alpha-lactone channel of the CH(3)CO+O(2) reaction is estimated to be 0.04+/-0.01 under 100 Torr of O(2) at 298 K. A simple kinetic model is employed to account for the decay of CH(3)C(O)OO.
Molecular machine for information reading and catalysis

The conversion of chemical energy into translational and rotational movement at the molecular level enables biological motors to perform and control a wide variety of complex functions. ‘Read-out’ tasks are essential for life as these processes can translate information from DNA to RNA and from RNA to encode proteins. 
The ‘ReadingMachine’ project aims to design, construct and investigate chemically fuelled linear molecular machines capable of active transport of cargo, the read-out information and other sophisticated tasks. Specifically, I will develop [2]rotaxane-based molecular machines for information storage and read-out. I will first investigate the rational design of an orthogonal gating system on the track to allow for the unidirectional transportation of a macrocycle through the track by fuelled acid-base oscillations. By recognition of the chiral information of each station it docks at, the macrocycle will be able to report its position through a unique CD signal output. Harnessing the unidirectional motion of the macrocycle on the track, sequential information of the track will be non-destructive read-out by a series of CD outputs. Furthermore, the information that the macrocycle is reading will change the conformation of the macrocycle. As a result, the reading process will enable the molecular machine to be a 'smart' catalyst for enantioselective synthesis according to the signal it reads. 
The controlled information storage and read-out process on molecular-level through a fuelled non-destructive reading machine is a tremendous challenge that could lead us towards the dawn of an era of useful molecular nanotechnology, for example ‘re-storage’ and ‘replication’ of stored information, and ultimately point the way for the use of such molecular machines to write (i.e. synthesize) sequence information as it is reading from the track.
Novel multimodal approach to atrial fibrillation risk assessment and identification of targets for prevention by interdisciplinary exploitation of omics, advanced electrocardiography, and imaging

There is a growing need for novel risk schemes in atrial fibrillation (AF) to permit prevention, contribute to a better understanding of the pathophysiology, and discover targets for individualized treatment.
Primary prevention efforts are scant despite the imminent AF epidemic. In international cohorts I have developed and validated the first risk prediction algorithm. However, it explains only 60% of the attributable risk and efforts at improving discrimination are urgently required.
Therefore, my overall goal is to develop an enhanced risk prediction algorithm based on cutting-edge technology. The specific focus will be on parameters representative of early stages of the disease process and intermediate phenotypes such as atrial electrical and structural remodelling, chronic subclinical inflammation, oxidative stress, and autonomous tone in manifest and incident AF. Subclinical, potentially reversible changes are ideally suited to provide independent information complementary to known risk markers.
My ambitious concept is to choose a multimodal approach in an interdisciplinary team to systematically assess:
1) Blood and tissue omics (genomics, expression, proteomics, metabolomics),
2) Advanced electrocardiography,
3) Imaging (echocardiography, cardiac MRI), and
4) Gender applying innovative tools and analyses strategies aimed at a systems biology integration of the accumulated information.
I have collected comprehensive biological and epidemiologic information on distinct AF phenotypes in unique prospective population (N>60,000) and clinical cohorts (N>1,000). We are not aware of other groups with access to such a well-established prospective AF biobank.
Informed by omics, electrocardiography and imaging we will provide pathophysiological insights into the disease process, highlight targets for intervention, and develop a contemporary risk scheme. Our results will lay the ground for rapid translation into clinical practice with significant public health impact.
Improvement of Methodologies and Governance of European Entrepreneurship Network

Business creation generates both growth and employment.  Therefore, encouraging people to become entrepreneurs is a strategic goal to exploit the endogenous potential of territories and to maintain the competitiveness of EU regions. Start-up support policies are also an innovative marketing tool for EU territories because they increase their attractiveness, .

Many EU regions have implemented policies which aim at increasing the number of new companies but also at improving the quality and sustainability of those companies (average survival rates in the main EU regions is about 60% 3 years after creation). Pre-start and post-start support has an impact on sustainibility but with an increasing number of would-be entrepreneurs and limited public resources, we have to maximise their efficiency. 
Some regions have also fostered networking between those involved in the business creation process.
Implementing such networks and governance models enables technical issues and best practice to be shared, relative contribution to successful start up to be evaluated and improves the visibility of support services.

The key objective of IMAGEEN is to benchmark best practice governance models and support methodologies. We will publish an Entrepreneurship Management Guide describing those best practices, analysing how they can be best transfered, and making recommendations to policy makers to improve the efficiency of entrepreneurship policy both locally and at the EU level.
This will be disseminated to all local stakeholders and policy makers but also on a European level at a large-scale EU dissemination event.
The IMAGEEN project will benefit from a large audience to disseminate its results and outputs since the project is supported by local policy makers and by ECER (European Cities Entrepreneurship Ranking) which each year organizes meetings for the TOP 40
Entrepreneurship Cities in Europe, within the EUROCITIES network.
Throughout the project, study visits will be organized to enable us to understand and describe precisely local practice in terms of governance (networking, monitoring systems) and support methodologies. Good practice and local issues will be highlighted.
This work will progressively enable us to build our Guide.

IMAGEEN partners will test out the transfer of best practice in their territories. An innovative entrepreneurship monitoring system will be jointly tested. One expected output of IMAGEEN is a common entrepreneurship barometer (10 permanent common indicators giving a global picture and enabling comparisons between EU Regions).

IMAGEEN will build an EU-wide network dedicated to the improvement of entrepreneurship policies and tools. One expected output of IMAGEEN is a concrete network methodology to enable IMAGEEN partner network sustainability and bring in new EU partners.
Aligning Bilingual Literary Works: a Pilot Study

Electronic versions of literary works abound on the Internet and the rapid dissemination of electronic readers will make electronic books more and more common. It is often the case that literary works exist in more than one language, suggesting that, if properly aligned, they could be turned into useful resources for many practical applications, such as writing and language learning aids, translation studies, or data-based machine translation. To be of any use, these bilingual works need to be aligned as precisely as possible, a notoriously difficult task. In this paper, we revisit the problem of sentence alignment for literary works and explore the performance of a new, multi-pass, approach based on a combination of systems. Experiments conducted on excerpts of ten masterpieces of the French and English literature show that our approach significantly outperforms two open source tools.
ATP-Sensitive Potassium Channels Exhibit Variance in the Number of Open Channels below the Limit Predicted for Identical and Independent Gating

In small cells containing small numbers of ion channels, noise due to stochastic channel opening and closing can introduce a substantial level of variability into the cell's membrane potential. Negatively cooperative interactions that couple a channel's gating conformational change to the conformation of its neighbor(s) provide a potential mechanism for mitigating this variability, but such interactions have not previously been directly observed. Here we show that heterologously expressed ATP-sensitive potassium channels generate noise (i.e., variance in the number of open channels) below the level possible for identical and independent channels. Kinetic analysis with single-molecule resolution supports the interpretation that interchannel negative cooperativity (specifically, the presence of an open channel making a closed channel less likely to open) contributes to the decrease in noise. Functional coupling between channels may be important in modulating stochastic fluctuations in cellular signaling pathways.
Practices and researches of dose interlock for SIEMENS linear accelerator

Objective: In radiation therapy, the accelerator will be stopped and interrupted treatment as soon as dose interlock appeared. And the linear accelerator dose interlock is multiple one in all kinds of the accelerator interlock faults. To study and explore general maintenance skills is in favor of quick analysis, and making the accelerator recovered in time, so as to ensure the normal treatment of the patients timely according to established plan. Methods: The author briefly analyzed the dose interlock and its factors, gave advice general maintenance skills and the general solving path of dose interlock, based on the dose interlock examples of SIEMENS ONCOR linear accelerator. Results: Using the general solving path, connecting with the practice, it can deal with most dose interlock troubleshooting and ensure the clinical radiation therapy. Conclusion: It has been found that the method to deal with these dose interlock is reliable and effective. It can help improve the maintenance speed and skill of dose interlock for engineers and technicians.
Consumer rejection threshold of ethyl phenylacetate and phenylacetic acid, compounds responsible for the sweet-like off odour in wines made from sour rotten grapes

Backgrounds and Aims: This study aimed to determine a consumer rejection threshold (CRT) for ethyl phenylacetate (EPhA) and phenylacetic acid (PhAA) in wine. These compounds have recently been reported to be responsible for sweet-like, honey off odours in wine made from sour rotten grapes. Methods and Results: Non-expert wine consumers (n = 35) received pairs of samples comprising a control wine against a spiked wine with an ascending concentration of the target compounds and were asked to indicate which sample they preferred. Results estimated a conjoint CRT for EPhA and PhAA of 140 and 700 mg/L, respectively. Wines spiked with a EPhA and PhAA concentration around the CRT evoked intense ‘dried fruit’ aromas that led to a decrease of the general aroma quality; these wines are significantly rejected by consumers. Conclusions: The measured CRT provides an initial estimation of the risk concentration for EPhA and PhAA in red wine, as they represent a ‘taint’ for regular wine consumers. Significance of the Study: These data allow wine producers to predict if a given wine will be disliked by consumers or to help guide ‘blending away’ of such wines.
Complex eco-evolutionary dynamics of aquatic ecosystems faced with human-induced and environmental stress

Resilience and recovery ability are key determinants of species persistence and viability in a changing world. Populations exposed to rapid environmental changes and human-induced alterations are often affected by both ecological and evolutionary processes and their interactions, that is, eco-evolutionary dynamics. The integrated perspective offered by eco-evolutionary dynamics is vital for understanding drivers of resilience and recovery of natural populations undergoing rapid changes and exposed to multiple stressors. However, the feedback mechanisms, and the ways in which evolution and phenotypic changes scale up to interacting species, communities, and ecosystems, remains poorly understood. The objective of my proposal is to bridge and close this gap by merging the fields of ecology and evolution into two interfaces of complex biological dynamics. I will do this in the context of conservation and sustainable harvesting of aquatic ecosystems. I will develop a novel mechanistic theory of eco-evolutionary ecosystem dynamics, by coupling the theory of allometric trophic networks with the theory of life-history evolution. I will analyse the eco-evolutionary dynamics of aquatic ecosystems to identify mechanisms responsible for species and ecosystem resilience and recovery ability. This will be done through systematic simulation studies and detailed analyses of three aquatic ecosystems. The project delves into the mechanisms through which anthropogenic and environmental drivers alter the eco-evolutionary dynamics of aquatic ecosystems. Mechanistic understanding of these dynamics, and their consequences to species and ecosystems, has great potential to resolve fundamental yet puzzling patterns observed in natural populations and to identify species and ecosystem properties regulating resilience and recovery ability. This will drastically change our ability to assess the risks related to current and future anthropogenic and environmental influences on aquatic ecosystems.
DEHYDRATION OF ALPHA-SUBSTITUTED CARBOXYLIC ACIDS IN THE PRESENCE OF WATER AT HIGH PRESSURES

The present invention describes a method for dehydrating alpha-substituted carboxylic acids in the presence of water at high pressures while preventing by-products.
Explicitly-correlated ring-coupled-cluster-doubles theory: Including exchange for computations on closed-shell systems

Abstract Random-phase-approximation (RPA) methods have proven to be powerful tools in electronic-structure theory, being non-empirical, computationally efficient and broadly applicable to a variety of molecular systems including small-gap systems, transition-metal compounds and dispersion-dominated complexes. Applications are however hindered due to the slow basis-set convergence of the electron-correlation energy with the one-electron basis. As a remedy, we present approximate explicitly-correlated RPA approaches based on the ring-coupled-cluster-doubles formulation including exchange contributions. Test calculations demonstrate that the basis-set convergence of correlation energies is drastically accelerated through the explicitly-correlated approach, reaching 99% of the basis-set limit with triple-zeta basis sets. When implemented in close analogy to early work by Szabo and Ostlund [36], the new explicitly-correlated ring-coupled-cluster-doubles approach including exchange has the perspective to become a valuable tool in the framework of symmetry-adapted perturbation theory (SAPT) for the computation of dispersion energies of molecular complexes of weakly interacting closed-shell systems.
Experiment of internal pressure response characteristics excited by sinusoidal external pressure for rigid structure with opening

A special experimental device was developed for researching internal pressure mechanism by using principle of sound vibrations,and the multi-parameter comparative experiments were conducted to study the internal pressure response characteristics for rigid structure with single opening excited by sinusoidal external pressure.Experimental results show that cavity resonance occurs for structure with opening excited by dynamic external pressure.With the opening area increasing,the cavity resonance frequency increases and damping ratio decreases.With the orifice depth and internal volume increasing,the cavity resonance frequency decreases and the damping ratio increases.For the openings with small aspect ratio and the same opening area,orifice shape has little effect on the cavity resonance frequency but has some influence on damping ratio.
Penile Ultrasound: An Essential Tool in an Emergency Setting (Traumatic and Non-Traumatic Diseases)

Penile conditions requiring urgent care are uncommon and result from trauma and a variety of non-traumatic causes. Some cases could rapidly evolve into an emergency situation and require prompt treatment to prevent severe complications. Therefore, correct and rapid diagnosis is fundamental. Although clinical history and physical examination are essential, diagnostic imaging is usually required to confirm the clinical diagnosis. In this setting, the sonologist in the emergency department has to be familiar with the basic US penile anatomy and with the most common US findings in urgent penile care. US is the key imaging method because it is readily available, safe, cost-effective, and well-tolerated by the patient. US can differentiate intracavernosal from extracavernosal hematomas and detect rupture of the tunica albuginea, consistent with penile fracture, that requires early surgical exploration. Color Doppler evaluation and spectral analysis are necessary to depict vascular abnormalities.Erkrankungen des Penis, die eine dringende Behandlung erfordern, sind selten und entstehen durch Trauma sowie durch unterschiedliche nichttraumatische Ursachen. Einige Fälle können sich schnell zu einer Notfallsituation entwickeln und erfordern eine sofortige Behandlung, um schwere Komplikationen zu vermeiden. Daher ist eine korrekte und schnelle Diagnosestellung von grundlegender Bedeutung. Wenngleich klinische Anamnese und körperliche Untersuchung unerlässlich sind, ist in der Regel die diagnostische Bildgebung erforderlich, um die klinische Diagnose zu bestätigen. Vor diesem Hintergrund muss der untersuchende Arzt in der Notaufnahme mit der grundlegenden Ultraschall- (US)-Anatomie des Penis sowie den häufigsten US-Befunden in der penilen Notversorgung vertraut sein. US ist die wichtigste bildgebende Methode, da sie leicht verfügbar, sicher, kostengünstig und für den Patienten gut verträglich ist. US kann intrakavernöse von extrakavernösen Hämatomen unterscheiden sowie eine Ruptur der Tunica albuginea erkennen, die einer Penisfraktur entspricht und eine frühzeitige chirurgische Exploration erfordert. Zur Darstellung von Gefäßanomalien sind Farbdoppler- und Spektralanalyse erforderlich.