SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
The Western Balkans countries relations with the EU: development and perspectives

The development of relations between Western Balkan countries and European Union represents very complicated and long-term process. During past few decades, Western Balkan countries made significant progress in that process, and as their primary goal defined common future with EU. Membership in the EU is a great incentive to the reforms, economic growth, democracy development, institutional frame constitution and stabilization in the whole region. Still there are lots of barriers and problems which obstruct those countries in their way of euro-integrations. To continue successful cooperation WB countries need to make effort in reforms implementation and approaching to European Union standards and values. In return, EU need to give full support and build appropriate capacities for preparation of Western Balkan countries for future membership. It is obvious that the association process will take a few more years. Countries of this region need to continue mutual cooperation and dialogue on all levels in order to avoid complications in relations and enlargement fatigue.
Circulating tumor dna as an epigenetic biomarker for tumor response

Tumors are characterized by a disorganized vasculature, leading to profound levels of hypoxia. Normalizing the blood vessel formation (angiogenesis) in tumors has therefore become an attractive therapeutic strategy, leading to the development of approved drugs that inhibit major angiogenic pathways. Resistance however restricts the success of these anti-angiogenic drugs in some patients. There is thus a great clinical need for readily accessible markers that serve as reliably predictive biomarkers of anti-angiogenic therapies. However, all markers discovered to date have a limited predictive power. In the ERC Consolidator Grant CHAMELEON, we discovered how tumor hypoxia causes DNA hypermethylation and how changes in DNA methylation underlie resistance to anti-angiogenesis. Here, we propose to validate how methylation patterns detectable in plasma circulating free DNA from a prospective collection of patients with metastatic colorectal cancer can be used to predict an early response to anti-angiogenic therapies by using our in-house developed cfDNA co-methylation test, referred as the ‘INITIATOR’ test. If successful, we anticipate that this project will overcome many of the issues that are currently associated with anti-angiogenic drugs: cfDNA is readily accessible and can be serially sampled during treatment or follow-up, cfDNA also mirrors the entire tumor and not just the biopsied site, while the epigenetic changes detectable in cfDNA may be a dynamic representation of the tumor in response to treatment.
Boosting the european innovative satellite technologies with in-orbit demonstrations

GOTOFLY! project aims first at building a wide portfolio of solutions and opportunities for the In-Orbit Demonstration and Validation of European satellite technologies and products, that are under development in Europe with the support of the EU, ESA, and national Space Agencies. Then we will design technically and programmatically several IOD/IOV missions from the portfolio, suitable to the Horizon 2020 context. Lastly, the GOTOFLY! project will promote its results among the stakeholders of the European Space sector.
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Therefore, the GOTOFLY! project gathers a teams of 5 enterprises of the European Space industry coming from 4 different countries: 
- 3 national branches of Thales Alenia Space (TAS) in France, Italy and Spain. TAS is a major satellites manufacturer and a leading player in the field of the Space R&D. It knows accurately the constraints for launching various satellites, then in-flight monitoring  payload parts
- Sea & Space Exploration in Belgium, an independent expert in analysing market trends and opportunities of the IC Technologies and satellite communication business
- NovaNano, a French SME developing IOD/IOV low-cost solutions based on nanosatellites.
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As a coordination action within H2020 programme, the GOTOFLY! Project proposes:
- to set-up a panorama of technologies and products that are of high interest for supporting new satcom applications & services, and for strengthening the competiveness and independence of the European space Industry.
- to catalogue the potentials IOD/IOV ‘carriers’ able to host these technologies &  products and to identify the launch opportunities: from nanosatellites to big GEO ones (which can merge a commercial mission with an experimental payload as a passenger)
- to select a set of IOD/IOV scenarios from the portfolio and to design these IOV/IOD missions on both technical and programmatic aspects, including the funding strategy. 
- and finally to recommend to Europe the best IOD/IOV for next H2020 phases.
STAPLE CARTRIDGE COMPRISING A VARIABLE THICKNESS COMPRESSIBLE PORTION

A fastener cartridge can comprise a support portion, a tissue thickness compensator positioned relative to the support portion, and a plurality of fasteners positioned within the support portion and/or the tissue thickness compensator which can be utilized to fasten tissue. In use, the fastener cartridge can be positioned in a first jaw of a surgical fastening device, wherein a second jaw, or anvil, can be positioned opposite the first jaw. To deploy the fasteners, a staple- deploying member is advanced through the fastener cartridge to move the fasteners toward the anvil. As the fasteners are deployed, the fasteners can capture at least a portion of the tissue thickness compensator therein along with at least a portion of the tissue being fastened.
British Colonial Office correspondence on the Cape Colony (1820-1821): Metatextual keywords vs. analytic categories

In 1820, Cape of Good Hope, British colony since 1795, became new home to c. 4,500 English-speaking settlers. Correspondence surviving from this period in reference to this settlement enables insights into early nineteenth century letters, still understudied area. Moreover, it provides good setting to disambiguate term from an internal, bottom-up perspective. Such perspective may offer a key for disclosing historical forms of communication (Hubler and Busse 2012: 1) as first-order phenomena. This is achieved in an analysis of categorial labels (keywords) and metacommunicative clues found in internal correspondence of Colonial Office, British government department, in years 1820-1821. The results of analysis provide partial answer to what label meant for this professional community. Adding researcher’s perspective to such description allows proposing twofold approach to the letter as an analytic category in study of historical correspondence
DERIVADOS DE ALCALOIDES CUATERNARIOS, COMPOSICIONES FARMACEUTICAS QUE LOS CONTIENEN Y SU USO EN EL TRATAMIENTO DE DISFUNCIONES METABOLICAS, INMUNOLOGICAS Y CANCER

Los productos de reaccion precipitados comprenden al menos un derivado de un alcaloide cuaternario y son adecuados como drogas para aplicaciones profilácticas o terapéuticas en composiciones farmacéuticas que los contienen, en particular en el tratamiento de disfunciones inmunologicas o metabolicas, y cáncer. Reivindicacion 1: Un producto de reaccion de alcaloides que comprende al menos un derivado de alcaloides fisiologicamente activo obtenido mediante la reaccion química de uno o más alcaloides con un agente de derivatizacion, caracterizado porque dicho al menos un derivado de alcaloides posee un nitrogeno cuaternario al cual se une, como cuarto ligando, un residuo de tipo base de Lewis, donde dicho residuo se selecciona del grupo formado por un residuo hidroxi (-OH), sulf-hidrilo (-SH), sulfoxi, sulfato, fosfato, éster, tioéster, éter, tioéter, alquilo, arilo, aralquilo, alquiloxi, ariloxi o un residuo o producto de descomposicion del agente de derivatizacion que no está comprendido en el grupo de compuestos mencionado precedentemente, con la condicion que dicho residuo no sea un residuo de hidrogeno, metilo o etilo.
Management of patients with excessive gingival display for maxillary complete arch fixed implant-supported prostheses

Maxillary complete arch fixed implant-supported prostheses are a popular treatment option for edentulous patients. Excessive gingival display or gummy smile in edentulous patients is relatively uncommon. However, many partially edentulous patients or completely dentate patients with compromised dentition and excessive gingival display may seek a fixed implant-supported prosthesis. Some of these patients may be candidates for immediate implant placement and insertion of the prosthesis, while others may carry over their preexisting excessive gingival display to the edentulous state for a variable period of time. Both types of patients require meticulous treatment planning and often require additional preprosthetic interventions before the placement of dental implants. This report provides an overview of the etiology, diagnosis, treatment planning, and options for management of patients with excessive gingival display who seek a maxillary complete arch fixed implant-supported prosthesis.
Optic neuropathy detection with three-dimensional optical coherence tomography

Based on optical coherence tomography (OCT) imaging of a portion of an eye, a mask of an anatomical feature is derived. Using the mask as a reference, a scan path is determined that is at least partially fitted to and/or partially enclosing the mask. OCT scan data corresponding to the scan path is acquired and analyzed to detect optic neuropathies.
Transport of heat in heterogeneous media

Geothermal represents a promising energy source to satisfy the growing energy needs with only minimal environmental impacts. To develop and test new technologies for energy production and storage in geothermal reservoirs, deep understanding of heat transport in fractured media is critically needed. The THERM project focuses on the investigation of heat transport and associated thermo-hydro-mechanical (THM) processes occurring during the lifetime of a geothermal reservoir. Fractured reservoirs, such as those found in enhanced geothermal systems, are characterized by a strong hydraulic and transport complexity coming from the fractures’ surface roughness, from their arrangement in networks, and from the interaction of the fractures with the surrounding rocks. As a result, the characteristics of the hydro-thermal flow which occurs when a cold fluid is injected into a hot fractured rock mass are controlled by fracture network discontinuities and properties of fracture surfaces themselves. While progresses have been made in characterizing and modeling subsurface heterogeneity in flow and solute transport processes, the effects of multi-scale subsurface heterogeneities on heat transport remains an open question. I propose new 3D fully coupled physical-based numerical models at different scales associated to state-of-the-art field experiments to develop a quantitative understanding of complex coupled processes occurring along fluid-rock interfaces during fluid circulation in geothermal systems. The main objectives are (i) to characterize the combined effect of fracture-scale and network-scale heterogeneity on flow and heat transport phenomena, and (ii) to design new field experiment to jointly measure the integrated THM behavior of fractures. Thanks to THERM, the ER will receive a unique multidisciplinary scientific training by Rennes 1 University that will reinforce significantly her expertise for future research activities and open new perspectives for career.
METHOD FOR DYEING TEXTILES, COMPRISING THE USE OF AN ORGANOSILICON COMPOUND, A DYEING COMPOUND AND A SILICONE OIL

The present invention relates to a method for dyeing textile materials, in which the textile material is brought into contact with an agent (a), an agent (b) and an agent (c), wherein: the agent (a) contains at least one organic silicon compound; the agent (b) contains at least one dyeing compound from the group including reactive dyes, pigments and/or substantive dyes; and the agent (c) contains at least one silicone oil.
Fabrication & characterisation of protective hea films on mg substrate by mechanical alloying, cold spraying & post-surface laser annealing processing

Protective high entropy alloys (HEA) thin films/coatings on Mg substrate will be produced by mechanical alloying (MA), cold spraying (CS) and post-surface laser annealing (SLA) process. By using variable but controlled MA process and CS  coating parameters (HEA feedstock powder & HEA MAed powder characteristics, CS technology geometric parameters, CS deposition parameters), variations in the micro-structure and property in HEA coatings will be attained. Microstructural characterization of HEA feedstock powders, MAed powders, CS coatings and CS+post-SLA coatings will be carried out by SEM, TEM, XRD, porosity measurements. Wear, oxidation, corrosion tests, hardness and elongation measurements will be made to determine chemical and mechanical properties of coatings. With this way relationships among deposition parameters-microstructure-properties will be determined in addition to the feasibility study of producing protective (wear and oxidation resistant) HEA coatings on Mg-parts by combined MA+CS & post- SLA process.
Molecular Simulation of the DMPC-Cholesterol Phase Diagram

In this paper, we present a coarse-grained model of a hydrated saturated phospholipid bilayer (dimyristoylphosphatidylcholine, DMPC) containing cholesterol that we study using a hybrid dissipative particle dynamics-Monte Carlo method. This approach allows us to reach the time and length scales necessary to study structural and mechanical properties of the bilayer at various temperatures and cholesterol concentrations. The properties studied are the area per lipid, condensation, bilayer thickness, tail order parameters, bending modulus, and area compressibility. Our model quantitatively reproduces most of the experimental effects of cholesterol on these properties and reproduces the main features of the experimental phase and structure diagrams. We also present all-atom simulation results of the system and use these results to further validate the structure of our coarse-grained bilayer. On the basis of the changes in structural properties, we propose a temperature-composition structure diagram, which we compare with the experimental phase and structure diagrams. Attention is paid to the reliability and interpretation of the model and simulation method and of the different experimental techniques. The lateral organization of cholesterol in the bilayer is discussed.
Effects of hydrocolloids on corn starch retrogradation

In this work, three kinds of hydrocolloids were used to investigate the effect of short-term and long-term retrogradation of corn starch to understand the mechanism of the hydrocolloid action on starch granules. Various analytical techniques, including the rapid viscosity analyzer, rheometer, differential scanning calorimetry (DSC), and dispersion stability analyzer, were used to determine the gelatinization and phase separation behavior and to understand the effect of hydrocolloids on the mechanism of starch retrogradation. DSC revealed that short-term retrogradation of amylose was retarded and restricted by xanthan gum. The X-ray diffraction indicated that the xanthan gum could prevent the recrystallization of amylopectin. The stability analysis, which was performed with the Turbiscan Easy Soft software, clearly suggested that addition of xanthan and guar gum can strongly stabilize the corn starch; this was quantified using the Turbiscan stability index. Thus, our results showed that xanthan and guar gum can improve the stability of corn starch/hydrocolloid systems.
A Historical Review of Computer User’s Illegal Behavior Based on Containment Theory

The aim of this study is to explore research trends in computer crime and cybercrime from 1968 to 2009. The findings of the current study will provide some insight into scholarly activity related to computer crime and cybercrime and will be useful in tracking computer user’s illegal behavior research trends. Our other goal is to explore the range of the theoretical lens that can be used to understand social controls in restraining computer user’s illegal behavior intention. Towards this goal, this study proposed five propositions based on containment theory. Our propositions address social control education, and offer insights in restraining computer user’s illegal behavior intention.
Preparation of the Horizon Europe Eurogrant application

SA.60012(2020/X) Name: Effective, sustainable and inclusive energy use (HORIZON-CL5-2022-D4-02-05) Date of submission: At the latest by the date specified in the notice, i.e. by 24 January 2023: 17:00. Organiser of the competition and website: The organiser of the competition is the European Commission. Website: https://ec.europa.eu/info/funding-tenders/opportunities/portal/screen/opportunities/topic-details/hor izon-cl5-2022-d4-02-05;callCode=null;freeTextSearchKeyword=;matchWholeText=true;typeCodes=1;statusCodes=31094501,31094502,31094503;programmePeriod=2021 %20-%202027;programCcm2Id=43108390;DivisionCode=null;programmePeriod=2021 %20-%202027;programCcm2Id=43108390;DivisionCode=null;focusAreaCode=null;destination=null;mission=null;geographicalZonesCode=null;programmeDivisionProspect=null;startDateLte=null;startDateGte=null;crossCuttingPriorityCode=null;cpvCode=null;performanceOfDelivery=null;sortQuery=startDate;orderBy=desc;onlyTenders=false;topicListKey=callTopicSepicTableState a) costs of preparing a feasibility study, b) activities related to the search for partners of the Eurogrant project and evaluation of the Eurogrant application, c) activities consisting of the preparation of the application/application for Eurogrant to the EU Programme, d) actions taken in connection with a possible correction of the Eurogrant application/application.
Communications cable with fabric sleeve

A communications cable (11) is provided with a pliant sleeve (12, 21, 31) to allow it to be more easily inserted into a conduit. One form of the sleeve (12) has hook (14) and loop (15) connected to each other so that the sleeve (12) can engage the cable (11). Another form of the sleeve (21) is spring-loaded to engage the cable (11). In a third form of the sleeve (31) has an adhesive (33) which attaches the sleeve (31) to the cable (11).
Gesture-recognition as basis for a human robot interface (HRI) on a AUV

An approach for gesture detection with a monocular camera on a moving vehicle is presented in this paper. The work consists of two parts. The first part deals with the video image processing. The main challenge here is the compensation of the ego-motion of the vehicle by image registration, which is required to facilitate the subsequent segmentation of relevant motions of the gestures. This is done with a spectral registration method, which proves to be useful for underwater scenarios. The second part deals with the recognition of gestures using motion trajectories. State machines where the different states are associated with the directions of movements are used for this purpose.
THERMALLY CONDUCTIVE ELECTRICAL INSULATION MATERIAL

A thermally conductive, electrical insulating paper having a thermal conductivity greater than 0.4 W/m-K is described. The thermally conductive, electrical insulating paper is a nonwoven paper that comprises aramid fibers, an aramid pulp, a binder material; and a synergistic blend of thermally conductive fillers, wherein the synergistic blend comprises a primary thermally conductive filler; and a secondary thermally conductive filler.
COVID-19 in vaccinated adult patients with hematological malignancies: preliminary results from EPICOVIDEHA

In a Plenary Paper, Mittelman and colleagues assess the relative clinical efficacy of mRNA vaccination on COVID-19 disease incidence and outcomes in patients with hematologic malignancies compared with healthy matched controls. This population-based study from Israel links prior observations of poor serologic responses to vaccination to higher risk for breakthrough infection, hospitalization, and death in patients with blood cancer, especially those on active antineoplastic therapy. In an accompanying Letter to Blood, Pagano et al provide supportive data using a multination survey approach to capture outcomes for COVID-19 in vaccinated patients with hematologic neoplasms. They also emphasize the higher risk among patients with lymphoid malignancies. Together, these findings argue for both continued deployment of booster programs and ongoing public health guidance for this vulnerable group.
European vehicle taxation

Transport remains a challenge, it is responsible of around 30% of global energy consumption and one of the major source of global pollution. Vehicles remain the dominant source of transport emissions and are responsible for 15% of Europe’s greenhouse gas emissions. A clear paradigm shift is needed to initiate the transition from fossil fuel-based driving towards mobility based on renewable resources, in particular towards electrification of transport through mass market take-up of BEVs. There are a number of technological burdens that need to be solved first, it will take another 5-7 years before these limitations are really solved to become competitive with ICEs. Hence, the reason for this project: re-thinking of road taxation systems starting from alternative inputs, including micro-mobility and SDGs as the main driver, to identify short(er) term solutions towards the initiation of a real transition and to prepare a smart, suitable and solid taxation system. The role of taxes is important to support the transition towards a fair green mobility. 
Transport taxation is a broad topic and this research is focused on vehicle taxation including all taxes connected to vehicles registration, purchase, ownership and use. This choice reflects also the new needs created by the pandemic: transport models and car industry are in crisis. Due to the crisis, a momentum is created to accelerate the shift from fossil fuel to BEV driving, including a re-thinking of the vehicle taxation system.
The overall objective of VTAX is to develop the fundaments for a new Mobility Taxation System, based on SDGs and alternative modes of electrified transport. The fellowship will last 24 months and will be carried out in Universidad San Pablo CEU (Madrid, Spain) with a secondment of 4 months at the International Bureau of Fiscal Documentation (Amsterdam, The Netherlands).