SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
The Female Genital Self-Image Scale (FGSIS): Validation among a Sample of Female College Students

Gynecological exams continue to be underused among young women, possibly due to a woman's genital self-image.The purpose of this study was to (i) examine college women's genital image using the Female Genital Self-Image Scale (FGSIS); (ii) assess the reliability, validity, and factor structure of data collected on the FGSIS; and (iii) examine the relationship between FGSIS scores and gynecological exam behaviors.Data were collected in November/December 2010 from 450 undergraduate women.Descriptive statistics were utilized to analyze demographic variables. A comprehensive psychometric assessment of the FGSIS included: (i) a reliability assessment of internal consistency; (ii) conducting a confirmatory factor analysis (CFA) to identify factor structure; and (iii) structural equation modeling and predictive discriminant analysis to asses the predictive qualities of the FGSIS on gynecological exam behavior.CFA analyses yielded a two-factor FGSIS structure: X(2) (12, N=450)=49.77; P<0.001, Root Mean Square Error of Approximation=0.08, Comparative Fit Index=0.98, Normed Fit Index=0.97. Reliability assessments indicated very good internal consistency for the scale (α=0.89), as well as for factor one (α=0.86) and factor two (α=0.82). Women who engaged in at least one gynecological exam during the past 24 months had a significantly more positive genital self-image than those who had not (t (449)=-2.501; P=0.01).Data collected using the FGSIS were found to be valid and reliable in this sample, further supporting the utility of the scale and aiding in the understanding of college women's genital image using an underlying two-factor approach. This has important implications for the development of sexual health and women's health programs and discussions. Specifically, a two-factor FGSIS can aid medical and health professionals in better understanding relationships between genital image and gynecological exam behavior.
Enhancing collaborative rule-making on global sustainability concerns through participatory design

This short paper outlines the background and prospects for a potential research agenda of Participatory Design (PD) in the area of collaborative transnational rule-making on global sustainability concerns. The paper adopts a pragmatic approach to interdisciplinary work, identifying new opportunities for PD by pointing to social science oriented processes that may be strengthened by the theory and practice of PD. With a theoretical foundation in legal philosophy on legitimacy and steps towards a deliberative democratic evolution of norms of conduct for global concerns, the paper is concerned with opportunities to involve a global citizenry in the evolution of norms of conduct that may affect the lives and futures of individuals. The paper describes research potential for PD towards enhancing information technology assisted inclusion of views, needs and concerns of individuals in transnational rule-making. It does so by drawing on the process that led to the 2011 United Nations Guiding Principles on Business and Human Rights. This process exemplifies challenges in collaborative and inclusive global rule-making that that may be assisted by increased and informed deployment of IT in order to enhance broad and balanced participation in the rule-making process.
Evaluation of an Epigenetic Profile for the Detection of Bladder Cancer in Patients with Hematuria

Many patients enter the care cycle with gross or microscopic hematuria and undergo cystoscopy to rule out bladder cancer. Sensitivity of this invasive examination is limited, leaving many patients at risk for undetected cancer. To improve current clinical practice more sensitive and noninvasive screening methods should be applied.A total of 154 urine samples were collected from patients with hematuria, including 80 without and 74 with bladder cancer. DNA from cells in the urine was epigenetically profiled using 2 independent assays. Methylation specific polymerase chain reaction was performed on TWIST1. SNaPshot™ methylation analysis was done for different loci of OTX1 and ONECUT2. Additionally all samples were analyzed for mutation status of TERT (telomerase reverse transcriptase), PIK3CA, FGFR3 (fibroblast growth factor receptor 3), HRAS, KRAS and NRAS.The combination of TWIST1, ONECUT2 (2 loci) and OTX1 resulted in the best overall performing panel. Logistic regression analysis on these methylation markers, mutation status of FGFR3, TERT and HRAS, and patient age resulted in an accurate model with 97% sensitivity, 83% specificity and an AUC of 0.93 (95% CI 0.88-0.98). Internal validation led to an optimism corrected AUC of 0.92. With an estimated bladder cancer prevalence of 5% to 10% in a hematuria cohort the assay resulted in a 99.6% to 99.9% negative predictive value.Epigenetic profiling using TWIST1, ONECUT2 and OTX1 results in a high sensitivity and specificity. Accurate risk prediction might result in less extensive and invasive examination of patients at low risk, thereby reducing unnecessary patient burden and health care costs.
Characterization and Calibration of the CheMin Mineralogical Instrument on Mars Science Laboratory

A principal goal of the Mars Science Laboratory (MSL) rover Curiosity is to identify and characterize past habitable environments on Mars. Determination of the mineralogical and chemical composition of Martian rocks and soils constrains their formation and alteration pathways, providing information on climate and habitability through time. The CheMin X-ray diffraction (XRD) and X-ray fluorescence (XRF) instrument on MSL will return accurate mineralogical identifications and quantitative phase abundances for scooped soil samples and drilled rock powders collected at Gale Crater during Curiosity’s 1-Mars-year nominal mission. The instrument has a Co X-ray source and a cooled charge-coupled device (CCD) detector arranged in transmission geometry with the sample. CheMin’s angular range of 5∘ to 50∘ 2θ with <0.35∘ 2θ resolution is sufficient to identify and quantify virtually all minerals. CheMin’s XRF requirement was descoped for technical and budgetary reasons. However, X-ray energy discrimination is still required to separate Co Kα from Co Kβ and Fe Kα photons. The X-ray energy-dispersive histograms (EDH) returned along with XRD for instrument evaluation should be useful in identifying elements Z>13 that are contained in the sample. The CheMin XRD is equipped with internal chemical and mineralogical standards and 27 reusable sample cells with either Mylar® or Kapton® windows to accommodate acidic-to-basic environmental conditions. The CheMin flight model (FM) instrument will be calibrated utilizing analyses of common samples against a demonstration-model (DM) instrument and CheMin-like laboratory instruments. The samples include phyllosilicate and sulfate minerals that are expected at Gale crater on the basis of remote sensing observations.
SELECTIVELY WETTABLE AND OXYGEN-PERMEABLE LENSES

A contact lens includes a body, having the plurality of monomers including at least some silicone monomer units including at least one zwitterionic distributed throughout the body. The contact lens includes a front surface and a back surface, where the silicone monomer including at least one zwitterionic group can be present in a greater concentration nearest the front surface than the back surface or a point therebetween. The contact lens can be formed by casting a polymer mixture containing the silicone monomer including at least one zwitterionic group.
Heart fine regulation through mechanosensing in myosin filaments: merging theory and experiments into a multi-scale heart simulator

Multi-scale heart simulators for patient specific treatments are an important challenge for the development of the health system, but require interdisciplinary interaction of several techniques to link experimental observations at the molecular level to the cardiac performance. The mechanosensing (MS) mechanism active in the myosin thick filament, recently discovered, is promising for the understanding of several unresolved questions in muscle field, including the molecular basis of the Frank-Starling law of the heart. MS mechanism finely regulates the number of myosin motors ready to generate force, sensing the tension sustained by the thick filament in any stage of the heart cycle. The mechanism appears to be crucial for the fine regulation of muscle contraction, deserving as a second regulator respect the classical Calcium concentration. However, its theoretical description at present is limited to purely phenomenological models and very few groups in the world are already able to produce clear evidences on it. The present project aims at establishing a collaboration between researchers in this field with complementary theoretical and experimental expertise to quantitatively characterize the MS mechanism at the fibre level through an innovative mathematical model and experimentally validate it with cutting-edge techniques present in the host and partner institutes. The fibre model will be included into a powerful whole heart simulator, to evaluate the macroscopic impact of MS mechanism, and its predicted effects on clinical problems, including its recently discovered relationships with cardiomyopathies. The project will foster an international network of collaborations, where the host institution will be a crucial node. The complimentary knowledges and high excellence of the groups, is a firm foundation on which to build the impact of the project: at my career level, at the institutes level and also at the system level.
Smart sensing for rapid response to chemical threats on soft targets

The overarching objective of this RISE programme is to set an international and inter-sectoral network consisting of 4 leading European academic institutions, an academic RTD centre and 4 SMEs working on a joint research programme around the topic of early and reliable warming detection systems of chemical threats on critical indoor infrastructures. The participants will exchange skills and knowledge in synthesis and fabrication of nanostructured materials, advanced sensing, surface enhanced Raman spectroscopy, energy harvesting technologies, signal processing algorithms and low-cost manufacturing strategies which will allow them to progress towards key advances in the domain of unattended sensing networks for chemical threats detection and strengthen collaborative research between five different countries. The beneficiaries also team up with excellent academic groups from third countries (2) with recognized expertise on wearable microanalytical systems and materials properties modelling to guarantee the techno-scientific viability of proposed idea. Advances in orthogonal sensing/detection technologies at sub-ppm level in gas phase will have potential market opportunities in the fields of early detection of airborne chemical warfare agents, early diagnosis of cancer or chronic diseases by biomarker detection, environmental monitoring in critical assets and process control in food and beverage industries. The staff members who participate in the project will acquire new scientific and technical skills by means of training at a network (e.g secondments),  be exposed to creative entrepreneurial and innovative research environment thanks to the strong interaction between academia and SMEs partners and have their career perspectives widened. The close cooperation among multidisciplinary partners from research institutions and SMEs will ensure knowledge transfer between academia and business in order to convert an academic concept to a viable and innovative product.
Implementation of the new technology as an opportunity to develop innovative products

The applicant, within the framework of this project, will implement a complete technological line for the production of a new type of pocket spring formats. The entrepreneur has great experience in developing modern furniture solutions – including pocket spring formats. As part of a previous EU project, it has made one of the most important implementations in this area in the country. Kerson can be considered, in many respects, as a precursor to new solutions and technologies. The project will be implemented in one step. The applicant will purchase a technological sequence – a digital device for the production of spring pocket formats using the unique and innovative country-wide two-head retractor technology with integrated assembly technology – also a digital device. The use of a two-headed solution will allow the Applicant to operate the retractor in parallel with the use of two different input materials – parallel production of a spring size pocket type using two different wires and the possibility of any configuration of the setting of individual springs. This solution is intended to respond to a very important problem at present – namely strengthening the rigidity of the format on its edges with the proper elasticity of the inner surface (it is easiest to illustrate this everyday problem of mattress users – sitting on the edge of the mattress with spring insert we feel discomfort associated with the extinction of the mattress and the loss of its rigidity/shape). The use of two different wires (plus the Applicant’s knowledge of modern solutions and results of previous projects) will allow the Applicant to create a more rigid format on the edges and standard in the rest of the area – the standard in this case means the latest solution available on the market, i.e. a zone insert.
The application of the time series theory to processing data from the SBAS receiver with safety of life service

Before satellite-based augmentation systems (SBAS) such as the Wide Area Augmentation System (WAAS) in the USA, and the European Geostationary Navigation Overlay Service (EGNOS), will be used in railway safety-related applications, it is necessary to determine reliability attributes of these systems as quality measures from the user's point of view. It is necessary to find new methods of processing data from the SBAS system in accordance with strict railway standards. For this purposes data from the SBAS receiver with the Safety of Life service was processed by means of the time series theory. At first, a basic statistic exploration analysis by means of histograms and box plot graphs was done. Then correlation analysis by autocorrelation (ACF), and partial autocorrelation functions (P ACF), was done. Statistical tests for the confirmation of nonstationarity, and conditional heteroscedasticity of time series were done. Engle's ARCH test confirmed that conditional heteroscedasticity is contained. ARMA/GARCH models were constructed, and their residuals were analyzed. Autocorrelation functions and statistical tests of models residuals were done. The analysis implies that the models well cover the variance volatility of investigated time series and so it is possible to use the ARMA/GARCH models for the modeling of SBAS receiver outputs.
IMPROVEMENTS IN OR RELATING TO LIQUID FLOW SYSTEMS

A liquid flow system comprising conduit means through which liquid is pumped in normal use, and including means to determine the level of particulate contamination within that liquid, comprising: a valve in communication with the conduit means and comprising a valve member (1) moveable relatively to a valve housing (4), in which the member can be set relative to the housing to define a narrow clearance (20) through which flow takes place; means to interrupt the normal pumped flow of liquid through the system and, when it is so interrupted, to cause liquid to flow instead through the said valve clearance, and means to monitor the volume of liquid so passed, and thereby to derive a measure of the degree of contamination of the liquid in the system characterised in that the flow through the said narrow clearance is in a direction substantially at right angles to that of the said relative movement of the valve member and valve housing.
Sex differences in expression in the shared genome

Males and females in many animals are strikingly different in behaviour, physiology, shape and form. In humans, rates of ageing and disease incidence vary markedly between the sexes. Moreover, sex differences in response to medical therapies and treatments have recently become an area of major biomedical concern. Because there are very few sex-limited genes, sex differences are largely a product of contrasting gene expression patterns between males and females4. Despite their ubiquity and clear biomedical importance, the evolutionary causes of sex differences in gene expression remain essentially unknown and pose a fundamental problem for biologists: How do sex differences evolve given that the sexes largely share the same genome?

My research addresses this fundamental question using two approaches: (1) a data-driven, large-scale phylogenetic approach, and (2) an experimental manipulation of chromosome dose in Drosophila melanogaster. The results from this project will create comprehensive understanding of sex-specific gene regulation and evolution. This broad research has important implications for medical, developmental and evolutionary studies of sex differences and addresses a key aim, as identified by the European Commission, for research excellence in Horizon 2020.
Dancing in the dark

“The baby, assailed by eyes, ears, nose, skin, and entrails at once, feels it all as one great blooming, buzzing confusion” (W.James Principles of Psychology, 1890). The hyper-connected teenager may not be far from such a state of confusion. Information overload leads to new cognitive and attention problems with social consequences, as seen in dramatic growth of attention disorders. Too much information leads to emotional and social malfunctioning, such as in autism. In the non-clinical population, continuously bombardment of the senses from multiple sources may lead to blunting and cause a cognitive or emotional blindness that has undesirable social and cultural consequences. DANCE addresses the role of multisensory information and the risks of overload by creating sensory deprivation as a means of sharpening the senses. DANCE not only want to look at how dance can influence socio-emotional perception in healthy individuals, but also focus on the congenitally blind. DANCE will compare social perception of dance and participation-blindness, found naturally in the congenitally blind, and induced in normally seeing subjects. DANCE will lead to the development of ICT (1) to treat the individual as an interactive participant in auditory perception rather than as a passive receiver; (2) to enable blind people to perceive movement by sensory substitution by means of innovative techniques of interactive sonification and active (embodied) music experience; (3) to integrate the individual experience and social creation process; (4) to assess and measure cognitive and cultural enhancement through non-verbal, full-body expression, emotion,and entrainment, and to explore how non verbal emotion dimensions can contribute to sensory substitution in the perception of dance and movement in general, for both blind and seeing people; (5) to explore and integrate theories of artistic creativity and to inspire novel scientific research challenges.
PROJECT CODE: 58126 — POR ERDF 2014/20 MARCHE REGION Â¿AXI 3 Â¿OS 8 — ACTION 8.1 — URBAN ITI “STOP 0-99+” — ACTIONS TO SUPPORT COMPETITIVENESS AND INNOVATION OF LOCAL MPAS FOLLOWING THE COVID 19 EMERGENCY.

PROJECT CODE: 58126 — POR ERDF 2014/20 MARCHE REGION Â¿AXI 3 Â¿OS 8 — ACTION 8.1 — URBAN ITI “STOP 0-99+” — ACTIONS TO SUPPORT COMPETITIVENESS AND INNOVATION OF LOCAL MPAS FOLLOWING THE COVID 19 EMERGENCY.
FLEXIBLE HOSE WITH SMOOTH INNER AND/OR OUTER WALL

Flexible hose comprising a corrugated wall of which an outer surface comprises a multitude of consecutive protrusions (1) and grooves (2) and of which an inner surface comprises a multitude of internal protrusions (4) and grooves (3), comprising a multitude of barriers for closing off each of the multitude of internal and/or external grooves (2), each of the multitude of barriers comprising a first closing leg (10, 12) of a first profile part and a second closing leg (11, 13) of a second profile part, the second closing leg being directed to the first closing leg, the first and second closing legs having a complementary shape provided to form a substantially smooth inner and/or outer surface.
Making morality: sustainable architecture and the pragmatic imagination

Environmental ethics as a discipline has directed little attention towards the built environment and even less to the process of building design. Conversely, within the professional context of architectural practice, questions of ethics and morality have hardly figured within a rapidly developing discourse of sustainability in which environmental values have tended to be downplayed in the pursuit of quantitative models of environmental innovation. The philosophy of pragmatism potentially provides a useful analytical and moral framework that links the environmental ethics of sustainability to the design, construction, and use of buildings. Pragmatism's embrace of contextual pluralism, its emphasis on experience and practice, and its high regard for the political worth of the community move the discussion away from a narrow focus on predefined and universal codes, whether ethical or technical. Sustainable design should be understood as a ‘co-evolutionary’ ethical practice, a socio-technical process that eng...
Aile Hekimliği Uygulamasının Hekimlerin Sunmuş Olduğu Hizmetlerin Kalitesine Etkisi: Düzce Örneği

The aim of this study is to examine the effect of family medicine system on the quality of health services provided by doctors. With this aim, this study focused on the consumer perceptions who receive health services from family doctors about family medicine system and the quality of services provided by family doctors. Research population consists of Duzce City which is used as a pilot city for the implementation of family medicine system. The questionnaire technique was used to collect the data and convenience sampling method was implemented. 450 questionnaires were evaluated in this study. The research data was analyzed by using SPSS package program. Analysis shows that the perceptions of participants about the quality of services taken from family doctors are positively influenced by the perceptions about the family medicine practice. In addition, it is revealed that there are differences between the perceptions about family medicine practice and the demographic characteristics of participants. Finally, it is founded that there are differences between the perceptions about family medicine practice and the quality of services provided by family doctors with respect to demographic characteristics of participants.
Energiesuffizienz erforschen: Neue Herausforderungen und Chancen in Krisenzeiten

Der Krieg in der Ukraine verändert die politischen Prämissen in rasender Geschwindigkeit. Wie sollen Politik und Gesellschaft auf hohe Energiekosten und eine fatale Abhängigkeit von fossilen Energieimporten reagieren? Können moderne Gesellschaften mit viel weniger Energie auskommen? Energiesuffizienz kann eine wichtige Rolle bei der Beantwortung dieser Fragen spielen. Die Beiträge in diesem Special topic erforschen Suffizienz als einen interdisziplinären Forschungsgegenstand für Energiemodellierung, -szenarien und -politik.
Next generation authentication for the digital age

The cost of cybercrime is rocketing—to $500 billion in 2015 according to The Economist. This is why European Commission introduced the Revised Directive on Payment Services (PSD2) to implement strong two-factor authentication for payments before 2018.

There are already several MFA solutions on the market, however they are suboptimal - expensive to implement, slow to use and do not meet requirements for PSD2, eIDAS and modern EC-funded approaches to crypto libraries. 

Notakey allows banks to implement a strong and scalable multi-factor authentication. The technology is made in a way that it can easily be implemented also in other industries, where there is need for protecting sensitive data.