SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Comparative efficacy and safety of two different molecular weight (MW) hyaluronans F60027 and Hylan G-F20 in symptomatic osteoarthritis of the knee (KOA). Results of a non inferiority, prospective, randomized, controlled trial.

To compare the efficacy and safety of a 'medium' molecular weight (MW) hyaluronan product (F60027, Structovial) with a 'high' MW (Hylan G-F20, Synvisc).Prospective, randomised, multicentre, double-blind, active controlled, parallel-group study with a non-inferiority design. Patients with symptomatic KOA, global pain ≥ 40 mm (VAS, 0-100), Lequesne index (LFI, 0-24) score >7 and radiological Kellgren-Lawrence grade 2/3 were centrally randomised to receive F60027 or Hylan G-F20, administered via three weekly injections, with regular follow-up evaluations up to week 24 (W24). The primary outcome was LFI score change over 24 weeks. Secondary outcomes comprised pain VAS, quality of life, patient's and physician's global assessments, rescue medication consumption and OMERACT-OARSI responders rate.276 patients were analysed in the full analysis dataset (FAS), 236 in the Per Protocol dataset (PP). In the main efficacy analysis (PP), the difference of the LFI score change over 24 weeks between F60027 (-4.67 (0.27)) and Hylan G-F20 (-4.54 (0.28)) was 0.132 [95%CI: -0.598, 0.861] which met the predefined non-inferiority margin. Analyses of secondary efficacy criteria showed clinically relevant improvements of all outcomes at W24 for each treatment on both PP/FAS populations. Changes of LFI score between baseline and W24 were -5.73 in the F60027 and -5.57 in the Hylan G-F20 group (PP dataset). Few local reactions were reported: 3.6% of patients in each group.F60027 and Hylan G-F20 were equally effective in reducing functional impairment and relieving pain in KOA patients, and well-tolerated.
Biomedical Research Centre Forestry — BIMIS

Biomedical research centre empowers the Institute of Medicine at the University of Zagreb (MEF), which increases the research, development and innovation capacity of an institution and supports the needs of the economy. Project documentation for infrastructure project implementation and organisational reform will be developed. The project involves the reorganisation of the scientific units by integrating the research practice of the MoEF and placing specialised research units into new laboratory areas after upgrading an existing building (Toolkit 4). The ultimate aim is to increase knowledge in the field of medical interventions by improving excellence and innovation, developing human resources and improving the economy and healthcare.
Representing Diversity in Communities of Bayesian Decision-makers

High-quality information has emerged from the contributions of many using the wiki paradigm. A logical next step is to use the wisdom of the crowd philosophy to solve complex problems and produce informed policy. We introduce a new approach to aggregating the beliefs and preferences of many individuals to form models that can be used in social policy and decision-making. Traditional social choice functions used to aggregate beliefs and preferences attempt to find a single solution for the whole population, but may produce an irrational social choice when a stalemate between opposing objectives occurs. Our approach, called collective belief aggregation, partitions a population into collectives that share a preference order over the expected utilities of decision options or the posterior likelihoods of a probabilistic variable. It can be shown that if a group of individuals share a preference order over the options, their aggregate will uphold principles of rational aggregation defined by social choice theorists. Super-agents can then be formed for each collective that accurately represent the preferences of their collective. These super-agents can be used to represent the collectives in decision analysis and decision-making tasks. We demonstrate the potential of using collective belief aggregation to incorporate the objectives of stakeholders in policy-making using preferences elicited from people about healthcare policy.
The Ten Most-Cited Papers in Journal of Emerging Technologies in Accounting: 2009 versus 2011

ABSTRACT This paper presents the ten papers from the Journal of Emerging Technologies in Accounting with the most Google Scholar citations. I find that nine out of ten papers from the 2009 list are on this 2011 list, suggesting that the most-cited papers are a relatively stable set at this time. Further, I find that the ten most-cited papers account for roughly 70 percent of the citations for the journal, to-date. Finally, over the last two years eight of the ten most-cited have at least as many citations as they did over the first five years of the journal and, for that eight, there were twice as many citations from 2009 to 2011, as there were from 2004 to 2009.
BIOPSY DEVICE

The invention relates to a device for endoscopic fine needle biopsy, in which control of the needle (2) is automatized by using a prestressed needle. On release of the spring (8), the needle shoots forward in the direction of the tissue, overcoming frictional force as a result of high acceleration. This reduces the danger of breaking the needle.
Rauchfeste Prüfung auf Brandschutzvorhänge und Widerstandsprüfung EN 1634-3; Gemäß EN 1634-1

Ziel des Projekts ist es, die Eigenschaften von Brandschutzvorhängen auf das Niveau zu bringen, dass das Produkt die in EN 1634-3 (Smoke susupability Sa und S200) festgelegten Kriterien erfüllt, wenn möglich, um die Produkte in Übereinstimmung mit der Norm EVS-EN 12101-1 zu bringen.
Levitation with localised tactile and audio feedback for mid-air interactions

This project will be the first to create, prototype and evaluate a radically new human-computer interaction paradigm that
empowers the unadorned user to reach into levitating matter, see it, feel it, manipulate it and hear it. Our users can interact
with the system in a walk-up-and-use manner without any user instrumentation.

As we are moving away from keyboards and mice to touch and touchless interactions, ironically, the main limit is the lack of
any physicality and co-located feedback. In this project, we propose a highly novel vision of bringing the physical interface to
the user in mid-air. In our vision, the computer can control the existence, form, and appearance of complex levitating objects
composed of ""levitating atoms"". Users can reach into the levitating matter, feel it, manipulate it, and hear how they deform it
with all feedback originating from the levitating object's position in mid-air, as it would with objects in real life. This will
completely change how people use technology as it will be the first time that they can interact with technology in the same
way they would with real objects in their natural environment.

We will draw on our understanding of acoustics to implement all of the components in a radically new approach. In particular,
we will draw on ultrasound beam-forming and manipulation techniques to create acoustic forces that can levitate particles
and to provide directional audio cues. By using a phased array of ultrasound transducers, the team will create levitating
objects that can be individually controlled and at the same time create tactile feedback when the user manipulates these
levitating objects. We will then demonstrate that the levitating atoms can each become sound sources through the use of
parametric audio with our ultrasound array serving as the carrier of the audible sound. We will visually project onto the objects to create a rich multimodal display floating in space.
Surface and volume charge transport properties of polyimide revealed by surface potential decay with genetic algorithm

It is very important to understand the surface and volume charge transportation properties of high insulating materials, such as polyimide, in order to find suitable method to mitigate the electrostatic discharge (ESD) of certain sensitive components on spacecraft. An isothermal surface potential decay (ISPD) experiment is performed inside a ground based vacuum chamber on polyimide under a simulated space environment. Immediately after low energy electron beam irradiation on polyimide, the 2D surface potential distributions are measured by a non-contact potential probe under five various temperatures from 298 to 338 K. The surface potential decay of the insulating material can be divided into two categories: transient process and steady state process. The steady state process is determined by the surface and volume charge transportation properties of dielectric. An ISPD model with genetic algorithm (GA) is developed to reveal the steady state surface potential decay experimental results. From the GA analysis, we obtain the surface resistivity, volume Ohmic resistivity, and charge carrier mobility of polyimide at various temperatures. After analyzing the surface and volume charge transportation properties of the material as a function of temperature, we find that the surface resistivity, volume Ohmic resistivity, and charge carrier mobility are well fitted with the Arrhenius law. Consequently, surface activation energy, volume activation energy, and trap energy of polyimide are found as 0.30 eV, 0.32 eV, and 0.54 eV, respectively.
Digital Media Strategies of the Far Right in Europe and the United States

With the leverage of digital reproducibility, historical messages of hate are finding new recipients with breathtaking speed and scope. The rapid growth in popularity of right-wing extremist groups in response to transnational economic crises underscores the importance of examining in detail the language and political mobilization strategies of the New Right. In Europe, for example, populist right-wing activists organized around an anti-immigration agenda are becoming more vocal, providing pushback against the increase in migration flows from North Africa and Eastern Europe and countering support for integration with a categorical rejection of multiculturalism. In the United States, anti-immigration sentiment provides a rallying point for political and personal agendas that connect the rhetoric of borders with national, racial, and security issues. Digital Media Strategies of the Far Right in Europe and the United States is an effort to examine and understand these issues, informed by the conviction that an interdisciplinary and transnational approach can allow productive comparison of far-right propaganda strategies in Europe and the United States. With a special emphasis on performing ideology in the far-right music scene, on violent anti-immigrant stances, and on the far rights skillful creation and manipulation of virtual communities, the contributions foreground the cultural shibboleths that are exchanged among far-right supporters on the Internet, which serve to generate a sense of group belonging and the illusion of power far greater that the known numbers of neo-Nazis in any one country might suggest. Moreover, with attention to transatlantic right-wing movements and their use of particularly digital media, the essays in this volume put pressure on the similarities among the various national agents, while accommodating differences in the virtual and sometimes violent identities created and nurtured online.
Metaplastic Breast Cancer: To Radiate or Not to Radiate?

The role of radiation therapy (RT) is unclear for metaplastic breast cancer (MBC). We hypothesized that RT would improve overall survival (OS) and disease-specific survival (DSS).We used the Surveillance, Epidemiology, and End Results (SEER) database to identify MBC patients diagnosed from 1988 to 2006. Univariate analyses of patient, tumor, and treatment-specific factors on OS and DSS were performed using the Kaplan-Meier method and differences among survival curves assessed via log rank. Variables assessed included patient age, race/ethnicity, histologic subtype, tumor grade, T stage, N stage, M stage, hormone receptor status, surgery type, and use of RT. Cox proportional hazards models used all univariate covariates. Risks of mortality were reported as hazard ratios (HR) with 95% confidence intervals (95% CI); significance was set at P ≤ 0.05.Among 1501 patients, RT was given to 580 (38.6%). Ten-year OS and DSS were 53.2, and 68.3%, respectively. In the overall analysis, RT provided an OS (HR 0.64; 95% CI, 0.51-0.82; P < 0.001) and DSS (HR 0.74; CI, 0.56-0.96; P < 0.03) benefit. When patients were stratified according to type of surgery, RT provided an OS but not a DSS benefit to lumpectomy (HR 0.51; CI, 0.32-0.79, P < 0.01) and mastectomy patients (HR 0.67; CI, 0.49-0.90; P < 0.01).Our findings support the use of RT for patients with MBC following lumpectomy or mastectomy. These retrospective findings should be confirmed in a prospective clinical trial.
Beidseitig bedienbarer Drehstangenverschluss für Kofferaufbauten

Ein Drehstangenverschluss (1) für eine Tür (2) eines Kofferaufbaus (3) eines Nutzfahrzeugs weist eine innere Betätigungseinrichtung (4) und eine äußere Betätigungseinrichtung (12) auf, die jeweils zum Öffnen und Schließen des Drehstangenverschlusses (1) dienen. Die innere Betätigungseinrichtung (4) weist einen mit der Drehstange (5) verbundenen inneren Betätigungshebel (8) zum Verdrehen der Drehstange (5) und eine Sicherungseinrichtung (9) mit einer Sicherungsstellung und einer Freigabestellung auf. Die Sicherungseinrichtung (9) ist so ausgebildet und angeordnet, dass sie in der Sicherungsstellung ein Verschwenken des inneren Betätigungshebels (8) und damit ein Verdrehen der Drehstange (5) verhindert und dies in der Freigabestellung ermöglicht. Die äußere Betätigungseinrichtung (12) weist einen mit der Drehstange (5) verbundenen äußeren Betätigungshebel (13) zum Verdrehen der Drehstange (5) und eine Freigabevorrichtung (14) mit einer Sicherungsstellung und einer Freigabestellung auf. Die Freigabevorrichtung (14) ist so ausgebildet und angeordnet, dass ein Verbringen der Freigabevorrichtung (14) von der Sicherungsstellung in die Freigabestellung die Sicherungseinrichtung (9) in deren Freigabestellung verbringt und somit ein Verschwenken des äußeren Betätigungshebels (13) und damit ein Verdrehen der Drehstange (5) ermöglicht
Changeable camouflage: how well can flounder resemble the colour and spatial scale of substrates in their natural habitats?

Flounder change colour and pattern for camouflage. We used a spectrometer to measure reflectance spectra and a digital camera to capture body patterns of two flounder species camouflaged on four natural backgrounds of different spatial scale (sand, small gravel, large gravel and rocks). We quantified the degree of spectral match between flounder and background relative to the situation of perfect camouflage in which flounder and background were assumed to have identical spectral distribution. Computations were carried out for three biologically relevant observers: monochromatic squid, dichromatic crab and trichromatic guitarfish. Our computations present a new approach to analysing datasets with multiple spectra that have large variance. Furthermore, to investigate the spatial match between flounder and background, images of flounder patterns were analysed using a custom program originally developed to study cuttlefish camouflage. Our results show that all flounder and background spectra fall within the same colour gamut and that, in terms of different observer visual systems, flounder matched most substrates in luminance and colour contrast. Flounder matched the spatial scales of all substrates except for rocks. We discuss findings in terms of flounder biology; furthermore, we discuss our methodology in light of hyperspectral technologies that combine high-resolution spectral and spatial imaging.
Clinical analysis of transurethral enucleation of prostate

OBJECTIVE To evaluate the clinical effect of the Plasma Kinetic enucleation of the prostate(PKEP)in treatment of benign prostatic hyperplasia(BPH).METHODS All of 300 cases of BPH were treated by transurethral enucleation of prostate using Plasma Kinetic.RESULTS The operations were all successful in 300 cases.The mean weight of the prostate was 60 grams.The operative time was 80 mins.The catheterization time was 3 days and the mean postoperative hospital stay was 5 days.No blood transfusion was performed in all cases.Histopathological analysis confirmed the diagnosis of BPH in all cases.IPSS mean decreased 22 and the peak urinary flow rate(Qmax)mean went up 12 ml/s and the residual volume of urine dropped to 100 ml.CONCLUSION PKEP is effective in treating BPH.It can completely enucleate the hyperplastic tissue with little bleeding in operation.The treatment has the advantages of short catheter time and significant clinical improvements.
Toxicological Evaluation of Ethanol Extract of Adenium obesum Stem Bark in African Catfish, <i>Clarias gariepinus</i>

The toxicity of ethanol extract of Adenium obesum stem bark as a tool foraquaculture pond management prior to the stocking of desired fish species was evaluated in Clarias gariepinus over a 96-h exposure. The fish were exposed to 6.25 mgL-1, 7.50 mgL-1, 8.20 mgL-1, 8.80 mgL-1 and 10.00 mgL-1 of the extract and a control in an acute static toxicity bioassay after performing a range finding test to determine the median lethal concentration (LC50) of the extract. Exposed fish showed signs of changed behaviours with adaptive responses, respiratory distress and nervous compromise, including mortality in some of the exposed fish. The appearance and intensities of the observed signs were concentration and exposure period-dependent. An LC50 value of 7.35 mgL-1 was establishedfor the extract in the exposed fish where mean mortality was significantly (p&lt;0.05) concentration and exposure period-dependent. The toxic nature of the extract in the exposed hardy fish can be exploited for effective aquaculture pond management against some unwanted predatory and weed aquatic organisms. However, the indiscriminate use of higher extract concentrations could seriously jeopardise the biodiversity of any aquaticenvironment.
Attachment structure for a constant velocity joint boot

When forcibly mounting a fixture (20) attached with a joint boot (18) on an outer circumferential surface of an outer cup (14), a thick-walled section (28) is pressed between an inclined surface (24) of the outer cup (14) and an annular stepped section (38) of the fixture (20). Accordingly, the thick-walled section (28) is elastically deformed and in close contact with the inclined surface (24) for effecting sealing function. <IMAGE>
DOC: ENABLING DIGITAL BUSINESS PROCESSES AND CONTENT

TO FILL IN IN THE LIGHT, WE BELIEVE THAT THE BUSINESS IS A CONTINUOUS FLOW OF INFORMATION AND DECISIONS, AND OUR AIM IS TO MAKE THIS FLOW FASTER, CONTINUOUS AND SMART. WE WANT TO IMPROVE THE BDOC PLATFORM, WHICH IS BASED ON ALCOOL AND SUCCESSFULLY IMPLEMENTED BY ITB: OPEN AND MODERN TO DIGITISE CRITICAL BUSINESS PROCESSES AND PROVIDE PEOPLE WITH THE NECESSARY INFORMATION QUICKLY AND WITHOUT EFFORT.
Phase 1b study of otlertuzumab (TRU-016), an anti-CD37 monospecific ADAPTIR™ therapeutic protein, in combination with rituximab and bendamustine in relapsed indolent lymphoma patients

CD37 is cell surface tetraspanin present on normal and malignant B cells. Otlertuzumab (TRU-016) is a novel humanized anti-CD37 protein therapeutic that triggers direct caspase independent apoptosis of malignant B cells and induces antibody-dependent cell-mediated cytotoxicity. This study evaluated the safety, pharmacokinetics, and efficacy of otlertuzumab administered in combination with rituximab and bendamustine to patients with relapsed, indolent B-cell non-Hodgkin Lymphoma (NHL).Patients with relapsed or refractory NHL received otlertuzumab (10 or 20 mg/kg) intravenously (IV) on days 1 and 15, bendamustine (90 mg/m(2)) on days 1 and 2, and rituximab (375 mg/m(2)) on day 1 for up to six 28 day cycles. Responses were determined using standard criteria.Twelve patients were treated with 6 patients at each dose level; median age was 57 years (range, 51-79), and median number of prior regimens was 3 (range, 1-4). All patients had relapsed after prior rituximab including 7 refractory to their most recent previous treatment. In the 10 and 20 mg/kg dose cohorts, the mean half-life was 8 and 10 days following the first dose, and 12 or 14 days following 12 doses of otlertuzumab, respectively. Overall response rate was 83% (10/12) with 4 CRs (32%). The most frequent adverse events were neutropenia, nausea, fatigue, leukopenia, and insomnia; most were grade 1 or 2.Otlertuzumab in combination with rituximab and bendamustine was well tolerated and induced responses in the majority of patients with relapsed indolent B-NHL. NCI Clinical Trials Network registration: NCT01317901.
Design and fabrication of a novel flowmeter with corrugated structure

We designed, fabricated and evaluate the novel air flowmeter with corrugation structure for the detection of low air velocity. For measuring the low air flow rate, the sensitivity related factors, the air drag force and the output signal, should be improved at the given air flow. The device has the paddle structure, and the maximized air drag force is obtained with vertical air flow. The output signal is also improved with the corrugation structure and measured with piezoresistive detection. The low air flow rate with less than 1m/s air velocity are applied, and the fabricated flowmeter with corrugation structure shows the better sensitivity and the response time than those of flat one. Various experiments about repeated measurements also show the stabilized signals.