SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Green tea polyphenol extract in vivo attenuates inflammatory features of neutrophils from obese rats

Our study aimed to evaluate whether obesity induced by cafeteria diet changes the neutrophil effector/inflammatory function and whether treatment with green tea extract (GT) can improve neutrophil function.Male Wistar rats were treated with GT by gavage (12 weeks/5 days/week; 500 mg/kg of body weight), and obesity was induced by cafeteria diet (8 weeks). Neutrophils were obtained from the peritoneal cavity (injection of oyster glycogen). The following analyses were performed: phagocytic capacity, chemotaxis, myeloperoxidase activity (MPO), hypochlorous acid (HOCl), superoxide anion (O 2 (·-) ), hydrogen peroxide (H2O2), IL-1β, IL-6 and TNFα, mRNA levels of inflammatory genes, calcium mobilisation, activities of antioxidant enzymes, hexokinase and G6PDH.Neutrophils from obese rats showed a significant decrease in migration capacity, H2O2 and HOCl production, MPO activity and O 2 (·-) production. Phagocytosis and CD11b mRNA levels were increased, while inflammatory cytokines release remained unmodified. mRNA levels of TLR4 and IκK were enhanced. Treatment of obese rats with GT increased neutrophil migration, MPO activity, H2O2, HOCl and O 2 (·-) production, whereas TNF-α and IL-6 were decreased (versus obese). Similar reductions in TLR4, IκK and CD11b mRNA were observed. Catalase and hexokinase were increased by obesity, while SOD and G6PDH were decreased. Treatment with GT reduced catalase and increased the GSH/GSSG ratio.In response to a cafeteria diet, we found a decreased chemotaxis, H2O2 release, MPO activity and HOCl production. We also showed a significant immunomodulatory effect of GT on the obese condition recovering some of these factors such H2O2 and HOCl production, also reducing the levels of inflammatory cytokines.
Life Course Epidemiology of Trauma and Related Psychopathology in Civilian Populations

Traumatic events are ubiquitous exposures that interact with life course events to increase risk of acute psychopathology and alter mental health trajectories. While the majority of persons exposed to trauma experience mild to moderate psychological distress followed by a return to pre-trauma health, many persons exposed to trauma experience substantial distress that lasts for several years. Therefore, in an effort to understand why exposure to trauma can provoke such a range of reactions, we apply a life course approach that considers the complex accumulation and interaction of life experiences that range from social to biological factors, which occur over the life span-from gestation to death and across generations. We present this evidence in three categories: genetics and biology, individual exposures, and community experiences, followed by discussing challenges in existing research and directions for future study.
Introduction to Scientific Computing

Computational science (or scientific computing) is concerned with constructing mathematical models and quantitative analysis techniques and using computers to analyze and solve scientific problems. In practical use, it is typically the application of computer simulation and other forms of computation from numerical analysis and theoretical computer science to problems in various scientific disciplines. Pascal is an influential imperative and procedural programming language, designed in 1968–1969 and published in 1970 by Niklaus Wirth as a small and efficient language intended to encourage good programming practices using structured programming and data structuring. Another object-oriented deviation of it was known as Object Pascal was developed in 1985. Today, Pascal is mainly abandoned in the industry or scientific teams however it has had its influence on both syntax and data structure of Java programming language, the most expressive language for scientific computing up to the time being.
Functional ecology of the plant-fungus interface: harnessing evolutionary genomics, transcriptomics and experimental ecology to dissect communication and nutrient exchange in a mutualistic symbiosis

This proposal aims to construct an evolutionary framework for the molecular interactions between ectomycorrhizal fungi and their plant hosts. Ectomycorrhizal (ECM) symbiosis is a mutualistic association between fungi and trees that is founded on reciprocal exchange of nutrients, facilitating growth in nutrient-limited or otherwise stressful environments. The symbiosis has evolved independently in many fungal clades, raising questions about its evolvability and the ecological redundancy of different ECM fungi. The ability of one ECM fungus to functionally replace another is especially salient in light of environmental change and loss of biodiversity. What components of communication between fungus and plant are conserved among ECM species? How conserved are molecular interactions at different phylogenetic scales? What are the molecular mechanisms responsible for phenotypic variation? ECM fungi from the genus Amanita will be grown together with the host Quercus robur (pendunculate oak). Q. robur displays endogenous rhythmic growth with alternating root and shoot flushes, distinct physiological states of growth that influence interactions with ECM fungi. The fungal strains are selected to survey variation i) between different Amanita ECM species and ii) in comparison with closely related saprobic Amanita sp., using a phylogenomic approach. We will profile genes expressed on both fungal and plant side at different time points: during mycorrhizal development and in mature mycorrhizas, while separating each time point into periods of root flush and shoot flush. We will profile a compendium of traits related to the functioning and success of ECM symbiosis at each developmental stage. Together these results will allow us to develop a detailed mechanistic view of the genes and pathways underlying ECM symbiosis, their evolutionary dynamics across a phylogenetic gradient of fungal partners and their impact on the different physiological stages of plant growth.
SYSTEM AND METHOD OF FLEXIBLY SORTING AND UNLOADING FINISHED PARTS DURING PART MANUFACTURING PROCESS

The invention relates to a system and method for sorting and unloading various pieces cut from sheet blanks having different dimensions in a sheet metal fabricating environment. Prior to the production run, various program routines stored in a controller (14) whose operations for effecting the cutting of the sheet blanks are retrieved and the data relevant to the to-be-cut pieces are grouped and analyzed so that pieces of different dimensions cut are respectively allocated to corresponding sorting addresses for unloading using an unloading arm (16). Different pieces with the same dimension cut from different program routines during the same production run are unloaded to the same location through the use of a stacker/unloader system (22). Optimization of the unloading process and optimal utilization of available loading is achieved.
Granularity Theory with Applications to Finance and Insurance

The recent financial crisis has heightened the need for appropriate methodologies for managing and monitoring complex risks in financial markets. The measurement, management, and regulation of risks in portfolios composed of credits, credit derivatives, or life insurance contracts is difficult because of the nonlinearities of risk models, dependencies between individual risks, and the several thousands of contracts in large portfolios. The granularity principle was introduced in the Basel regulations for credit risk to solve these difficulties in computing capital reserves. In this book, authors Patrick Gagliardini and Christian Gouriéroux provide the first comprehensive overview of the granularity theory and illustrate its usefulness for a variety of problems related to risk analysis, statistical estimation, and derivative pricing in finance and insurance. They show how the granularity principle leads to analytical formulas for risk analysis that are simple to implement and accurate even when the portfolio size is large.
The Role of Children's Health in the Intergenerational Transmission of Economic Status

Intergenerational mobility is relatively low in the United States. Children who grow up in poverty are eight times more likely to live in poverty in adulthood than their counterparts who do not live in poverty. What is it about growing up in poverty that reduces the probability of economic success later in life? On average, children whose families live in poverty have lower levels of cognitive skills, noncognitive skills (e.g., behavior including perseverance and adaptability), and health, all of which contribute to earnings in adulthood. In this article, I examine the role children's health plays in intergenerational transmission of economic status from an economic perspective and in the context of a developed, high-income country (the United States). Evidence suggests that the mechanisms by which parents’ income affects children's health include, but are not limited to, reduced access to health insurance and medical care, greater exposure to environmental toxins, inadequate nutrition, and greater family violence and stress. I conclude with evidence suggesting that public investments in children's health can reduce the intergenerational transmission of economic status and the inequality of the next generation in the United States, as well as in other less developed nations.
Dynamic capture of low-concentration CO2 on amine hybrid silsesquioxane aerogel

Abstract Amine hybrid silsesquioxane aerogel (AHSA) was synthesized through a single-step sol–gel process followed by supercritical drying. CO2 adsorption performances of highly porous AHSA in 1% CO2 were investigated. 50 °C is preferred to perform the CO2 capture of AHSA to achieve a CO2 adsorption capacity of 3.04 mmol/g (dry) or 3.84 mmol/g (humid) under given conditions. A rise in adsorption gas flow rate from 300 to 700 ml/min results in the decrease of CO2 adsorption capacity from 3.04 to 2.42 mmol/g. The CO2 adsorption rate is mainly affected by the gas flow rate, while the effect of temperature can be ignored. Different with the adsorption performance, the CO2 desorption kinetics of AHSA is mainly affected by the temperature, the effect of gas flow rate is indifferent. Water favors the CO2 capture capability of AHSA, however, it is bad for the CO2 adsorption and desorption kinetics. The CO2 adsorption capacities of AHSA in 1% CO2 are much higher than those of other amine based porous adsorbents obtained with a 1% or even higher CO2 gas mixture. Also, AHSA has very short adsorption half time (22–55 s) and low desorption temperature of 80 °C, much lower than those of other amine-based adsorbents. The resulting adsorbent is dynamic and possesses excellent regenerability for low-concentration CO2 capture.
Carlo goldoni and europe's new opera theatre

Venetian playwright Carlo Goldoni (1707-1793), famous for his ‘reform’ of comic theatre, was also a prolific librettist. Research has focused largely on Goldoni’s early texts for music, while the libretti written during his mature years have remained overshadowed by his most famous comedies. With growing attention to interdisciplinary studies, the time is now ripe for these later texts for music and the operas drawn from them to be brought to light, because, most importantly, precisely through these libretti Goldoni became a pioneer in the creation of the 'dramma giocoso,' a new genre of opera that would span a long legacy throughout Europe, all the way to the works of W.A. Mozart and Lorenzo Da Ponte. 
The goal of this project is the recovery and analysis of operatic renditions created from the innovative drammi giocosi by Goldoni, today nearly forgotten, to finally supply a comprehensive picture of the interaction between text, music, and theatre that fueled the radical evolution of Classical opera in the later 18th century. The study of these selected works will also yield a more detailed map of the artistic collaborations and diffusion of this new genre on an international scale.
On a broader horizon, this project ultimately aims to create the basis for the restoration, publication, and performance of historical opera scores that have vanished from the traditional repertoire. These operas will become a source of new discoveries in both literary and musical fields, and their restoration through performance with the involvement of young musicians and scholars in conservatories and universities will not only render just merit to Goldoni for his innovations in opera theatre, but most importantly will bring to a larger public new knowledge of a form of art that had a global impact, and therefore a deeper understanding of our shared cultural heritage.
Cost-Effective recycling of cdw in high added value energy efficient prefabricated concrete components for massive retrofitting of our built environment

Around 461 million ton/year of C&DW are generated in EU28. Recent studies  on the characterization of C&DW samples at European level revealed a predominant fraction of concrete (52% average). Over the last years, novel technology has been developed aiming to guarantee high quality recycled concrete aggregates for use in new concrete, thereby closing the concrete loop. The most advanced concrete recycling technologies currently produce coarse (>4mm) recycled concrete aggregates by removing cement paste from the surface of the aggregates. However, the fine (0-4 mm) fraction, ca. 40% of the concrete waste, still faces technical barriers to be incorporated into new concrete and consequently, is often down-cycled. At the other extreme, there are minor (e.g. glass) and emerging (e.g. mineral wool) C&DW materials, currently accounting for 0.7% of the total, but revealing growing rates as consequence of European regulations. Those emerging C&DW streams have not yet found technological and business solutions, being mostly landfilled. On the other hand, concrete is the most widely used material in building, with a growing trend towards prefabrication. The European precast concrete sector faces diverse needs for resource efficiency improvement (reduction in natural resource consumption and metabolization of waste materials, reduction in carbon footprint and embodied energy, design for reuse, increase in process efficiency and waste minimization, lighter solutions, enhanced thermal performance through novel cost-effective insulating materials). Aiming at facing these challenges, VEEP main objective is to eco-design, develop and demonstrate new cost-effective technological solutions that will lead to novel closed-loop circular approaches for C&DW recycling into novel multilayer precast concrete elements (for both new buildings and refurbishment) incorporating new concretes as well as superinsulation material produced by using at least 75% (by weight) of C&DW recycled materials.
Pseudomagnetic fields for sound at the nanoscale

Significance Unlike electrons, phonons do not feel a magnetic field, because they are not charged. Thus, much of the physics connected with charged particles in magnetic fields is absent for phonons, be it the Lorentz force or the unidirectional transport along the sample edges. Recently, researchers have started to study how one might make phonons akin to electrons in a magnetic field or related topological settings. The first experimental implementations involving coupled pendula or gyroscopes or air currents have already been realized at the macroscopic scale. Here, we describe a design that is well-suited for the nanoscale. It is purely geometric in nature and could be implemented based on an already experimentally demonstrated platform, a simple patterned 2D material.
Allocating surveillance resources to reduce ecological invasions: maximizing detections and information about the threat

Allocating resources to detect invasive pests, diseases, and pathogens on exposure pathways requires a trade-off between the need to detect as many contaminated items as possible and the need to acquire knowledge about contamination rates. We develop a model and an algorithm that provide guidance for the allocation of inspection resources across multiple dynamic pathways in cases where not every item can be inspected. The model uses a null hypothesis that the contamination rate of a pathway is above a specified level: a risk cutoff. Pathways with a risk above the cutoff are fully inspected, and those with a risk below the cutoff level are monitored at a rate that would detect a change of the risk to being above the cutoff level with high probability. We base our decision on the 95% upper confidence limit for the contamination rate. We demonstrate via simulations and a data set that focusing inspection resources on specific pathways can result in substantially more effective intervention, and that the reduction in overall effectiveness of monitoring low-risk pathways need not be substantial. Use of the model demands the selection of the risk cutoff, and this limit can be set according to projected consequences.
STORAGE COMPARTMENT FOR A MOTOR VEHICLE

The invention relates to a storage compartment for a motor vehicle, with a container (110) and a container lid (112) arranged pivotably on the container, a pivot lever (116) arranged on the container lid, a first elastic element (120), the first end of which (122) is connected to the container and the second end (118) of which is connected to the pivot lever such that the first elastic element exerts a closing force and/or a closing moment on the container lid, and a locking element (126) which is mounted pivotably such that its inertia causes it to be brought, in the event of an impact of the motor vehicle, into a locking position in order to retain the pivot lever, wherein the locking element is mounted pivotably about the first end of the first elastic element, wherein the first elastic element is a dead-centre spring, and wherein the dead-centre spring is designed such that it exerts the closing force and/or the closing moment until an open position of the container lid does not exceed a dead-centre position (155).
Frequency synthesizer and multi-band radio apparatus using said frequency synthesizer

The frequency synthesizer comprises an HF synthesizer (11) for generating a first reference frequency signal having a variable frequency in a highfrequency band as a unit synthesizer, an LF synthesizer (12) for generating a second reference frequency signal in a low-frequency band as another unit synthesizer, and an arithmetic circuit including a mixer (13) for receiving the first and second reference frequency signals, a divider (14) for receiving the second reference frequency signal, a mixer (15) for receiving the first reference frequency signal and an output signal from the divider (14), a divider (16) for receiving an output signal from the mixer (14), a divider (17) for receiving an output signal from the mixer (15) and capable of switching a division ratio, and a switch (18) for switching and outputting output signals from the dividers (16, 17), wherein an output signal of the switch (18) is outputted as a first local signal, and an output signal from the divider (17) is outputted as a second local signal.
Science and innovation with thunderstorms

Lightning is an extremely energetic electric discharge process in our atmosphere. It significantly affects the concentration of greenhouse gases and it threatens electrical and electronic devices, in particular, when placed on elevated structures like wind turbines or aircraft, and when these structures are built with modern composite materials with inherently low electric conductivity. In addition, even our fundamental understanding of atmospheric electricity is far from complete. New discharge processes in the atmosphere above thunderstorms have been discovered, the so-called Transient Luminous Events (TLEs)   in the stratosphere and mesosphere, and Terrestrial Gamma-ray Flashes (TGFs) that emit particle beams of antimatter. These phenomena demand thorough investigations, in geophysics and in the related fields of plasma and high-voltage technology where similar discharges appear.
These challenges are approached within the SAINT project with a multidisciplinary and inter-sectorial training platform for 15 ESRs. The platform brings together satellite and ground observations with modelling and lab experiments. It couples scientific studies to applications relevant to industries developing satellite data products, plasma discharge technologies, lightning detection systems and lightning protection devices.  
With SAINT, we take advantage of the extraordinary opportunity presented by three simultaneous space missions with dedicated instruments to study lightning discharges, TLEs and TGFs, to integrate the unique space data with dedicated novel ground observations, model developments and lab experiments. SAINT will train the next generation of young, innovative scientists to shape the future of  research and technology in Europe.
Negotiation as an intersubjective process: Creating and validating claim-rights

Negotiation is mainly treated as a process through which counterparts try to satisfy their conflicting interests. This traditional, subjective approach focuses on the interests-based relation between subjects and the resources which are on the bargaining table; negotiation is viewed as a series of joint decisions regarding the relation of each subject to the negotiated resources. In this paper, we will attempt to outline an intersubjective perspective that focuses on the communication-based relation among subjects, a relation that is founded upon communicative rationality mechanisms which are inherent in social activity. Much in contrast to the concept of interests which describe the relationship of each subject alone to the resources, we will use the concept of “claim-rights” which are properly formed and validated only vis-a-vis negotiating partners and on the basis of the communication that develops among them. We will offer a step-by-step account of the creation of claim-rights and argue that their va...
Sustainable Local Economic Development: The Role of Informatics in Determining Municipal Revenue Management

This paper discusses the challenges undermining the ability of smaller municipalities in South Africa (SA) to raise revenue to sustain local economic development (SLED). The concept of enactment of technology-in-practice (ETiP) of Structuration Theory (ST) was adopted as a lens to understand and interpret the factors hindering the implementation of relevant legislation e.g., the municipal property rates Act of 2004 (MPRA) for SLED. The purpose of the study was to determine the role informatics can play in the implementation of MPRA to institutionalise its provisions to improve revenue collection. An extensive investigation in twenty-five (25) smaller municipalities across SA indicated a number of factors suggested by ETiP have impacted on the implementation of MPRA and property rates collection. The view is that implementation of legislation e.g., MPRA is similar to the deployment of ICT solutions in governments. Thus, in the world of social theory, legislation implementation is a socio-technical phenomenon with significant political, economic and social components. The findings of the study is a general framework as a lens through which factors influencing SLED can be understood and interpreted to provide a richer understanding of the complexity associated with the role of informatics in government revenue management to support SLED.