SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
The study of the relationship between the performance of fuzzy goal programming method and production factor promotion

In order to determine a systematic method for increasing productivity, different methods have been implemented. However, these methods were mostly used for measuring the current situation and implementing a suitable instrument for the purpose of presenting an efficient solution in order to promote the productivity seems essential. For this purpose, operational research method is one of the most efficient and useful tools which tries to make the best advantage of them and use them systematically by implementing optimal resources. Using an goal planning tool through determining the essential goals for promoting productivity is a modern method which has attracted the attention of productivity areas and is able to study the interaction between the essential elements with productivity promotion approach. The purpose of this research is to study the relation between performing Fuzzy Goal Programming Method and productivity promotion of production factors such as the promotion of materials, capital productivity, and human resources. The deign used for this method is applied, analytic and descriptive. Twenty four hundreds experts from five major detergents companies existing in detergents industrial clusters were considered as the population of the present study. The results indicated that there is a positive strong relation between the three factors including promotion of materials, capital productivity, and human resources by implementing goal planning model.
Nanoarchitectronics

This FET-open Coordination and Support Action is called “Nanoarchitectronics” (NTX) to denote a new interdisciplinary research area at the crossroad of Electromagnetics and Nanoelectronics. NTX It is a new technology aimed at conceiving, designing and developing reconfigurable, adaptive and cognitive structures, sensorial surfaces and functional “skins” with unique physical properties, and engineering applications in the whole electromagnetic spectrum; through assembling building blocks at nanoscale in hierarchical architectures. The conception of this new area responds to the need of unifying concepts, methodologies and technologies in Communications, Environment Sensing Systems, Safety and Security, Bio-Sensing Systems and Imaging Nanosystems, within a wide frequency range. This FET project proposal gathers thirteen universities, research centers and high-tech industries, belonging to eight European countries.  
According to the FET work-program, the major objective of “Nanoarchitectronics” is to boost the future application-driven research through the establishment of an accepted language among physicists and engineers, a shared way of thinking, a common theoretical foundation and a common strategy for the future. Therefore, the project aims at laying the foundation for an ever-increasing synergy and progress of Nanoarchitectronics. 
To achieve these objectives, Nanoarchitectronics is structured in four main activities. The “Concept” activity is devoted to establish and define the concepts of Nanoarchitectronics and its boundaries with respect to other disciplines and to the activity carried out by other consortia. The “Strategy” activity identifies the policy dialogue and the strategic view of the consortium in terms of position, impact and vision. The “Virtual Networking” serves to internal web communication (private), and for dissemination (public). The “Dissemination and Exploitation” activity is carried out mainly by the industrial partners of the consortium
“Filmagining” Ethnicities: The Making of a Chinese Nation with Film Genres and Styles between 1940 and 1963

This article is about the movies from Chinese mainland under the production category of minority cinema (shaoshu minzu dianying), between the years 1940 and 1963. It argues that the taxonomic effort of grouping different non-Han ethnicities together into a single category of minority cinema is a sociopolitical attempt to construct, maintain and control the definition of ethnic minorities. It calls into question not what is within the film, but the classificatory practices outside of the film collectively engaged by the government, the film industry, the critics and the mass audience. Moving away from the methods of examining the representation and generic conventions of the cinema other scholarship has employed, this article emphasizes the classification system used during the time of the cinema. By comparing it with a similar classificatory problem in Western national history, using an epistemological perspective, this article criticizes the negative impact inevitably left in rhetorically driven classification systems.
Bridging biobanking and biomedical research across europe and africa

B3Africa - Bridging Biobanking and Biomedical Research across Europe and Africa will dramatically improve and facilitate the development of better predictive, preventive and personalized healthcare worldwide. The rapidly evolving African biobanks are an invaluable resource: The African population has the greatest genomic diversity on the planet and represents an incredible resource of information to advance biomedical research. B3Africa aims to implement a cooperation platform and technical informatics framework for biobank integration between Africa and Europe. The collaboration harmonizes the ethical and legal framework, biobank data representation and bioinformatics pipelines for sharing data and knowledge among biobanks and allowing access for researchers from both continents. Main actors from the relevant initiatives including Human Heredity and Health in Africa project (H3Africa), European Biobanking and Biomolecular Resources research infrastructure (BBMRI-ERIC) and LMIC Biobank and Cohort Network (BCNet) collaborate in B3Africa to address the following objectives:
• Defining an ethical and regulatory framework for biobank data sharing between Europe and Africa
• Defining data models for representing biobank and research data based on existing best practices, standards and ontologies
• Designing an informatics platform using existing open-source software (with eBioKit and BiBBox as essential modules) integrating workflows for biobank applications
• Implementation of an education and training system for information and capacity building
• Validating the B3Africa concept with existing biobanks from both continents
B3Africa will provide the critical mass to maximise efficiency in biomedical research, supports defragmentation through integration and allows efficient leverage of existing biobanks and e-infrastructures in Europe and Africa. The technical informatics framework will be designed for easy upscaling and integration with other research infrastructures.
SWITCH ELEMENT COMPRISING A LIQUID CRYSTALLINE MEDIUM

The invention relates to a temperature-controlled switch element for regulating light transmission. The invention further relates to a mixture comprising at least one liquid crystalline bond, at least one monomer bond, which represents a mono-functional bond, and at least one monomer bond, which represents a multi-functional bond. The invention further relates to the use of the cited mixture for producing the switch element according to the invention.
Restoration of the insulation of ice-covered post insulators

This article describes a technique used to deice and restore the external insulation of post insulators covered with ice in the process of melting. Tests were done in the large environmental chamber at Universite du Quebec a Chicoutimi's research pavillion on atmospheric icing. Post insulators were covered with ice and subjected to conditions close to the electrical flashover. The surface of the post insulators was cleaned with a powerful steam jet. This considerably reduced the leakage currents and, as a result, the insulation of the post insulators could be restored. The improvement of the insulation was estimated based on a simple model where the arc is propagated on a polluted surface.
Sleep-related symptoms and sleep-disordered breathing in adult Pompe disease

Respiratory muscle weakness is the major cause of early death in patients with adult Pompe disease. It first manifests as nocturnal hypercapnia, eventually leading to sleep disruption. Sleep-related symptoms along with motor performance, forced vital capacity (FVC) and respiratory symptoms were investigated in 65 adult patients with Pompe disease.Patients answered the Pittsburgh Sleep Quality Index (PSQI), the Epworth Sleepiness Scale, the Fatigue Severity Scale, the Rotterdam Nine-item Handicap Scale, the SF-36 health-related quality of life questionnaire, and a respiratory symptom questionnaire. In all patients, the 6-min walk test was performed and FVC was obtained. Polysomnography and oxycapnometry results were available in 31 patients.Sixty patients received enzyme replacement therapy, and 32 individuals were on home ventilatory support. Reduced sleep quality was highly prevalent (PSQI > 5; 43.1%) and correlated with both excessive daytime sleepiness (Epworth Sleepiness Scale > 10; 24.6%) and fatigue (Fatigue Severity Scale > 4; 72.3%). The SF-36 health-related quality of life questionnaire was reduced in the physical domains, and was inversely correlated with sleep quality, FVC and motor performance. In 11 out of 17 non-ventilated patients with polysomnography records, sleep-disordered breathing was present, and duration of nocturnal oxygen desaturation (SaO2 < 90%) was significantly correlated to the PSQI global score.In adult Pompe disease, sleep disturbances are a common cause of excessive daytime sleepiness and fatigue. Sleep-related symptoms may be indicative of respiratory muscle weakness and should give rise to further work-up of sleep-disordered breathing.
METHOD AND APPARATUS FOR ELECTROWINNING COPPER USING AN ATMOSPHERIC LEACH WITH FERROUS/FERRIC ANODE REACTION ELECTROWINNING

The present invention relates, generally, to a method and apparatus for recovering metal values from a metal-bearing materials, and more specifically, a process for recovering copper and other metals through leaching, electrowinning using the ferrous/ferric anode reaction, and the synergistic addition of ferrous iron to the leach step.
Systematic search of regulatory elements controlling autosomal monoallelic expression

Autosomal monoallelic expression (MAE) is an epigenetic phenomenon that controls the relative expression of maternal and paternal alleles in thousands of mammalian genes. Despite MAE’s widespread character the molecular mechanisms involved in its establishment and maintenance are yet to be clarified. Recent work shows that the sets of genes subject to MAE are highly consistent across individuals and conserved between human and mouse species. I propose to test that such conservation is due to specific regulatory elements in the genome associated with MAE genes. The strategy to discover such elements is via a systematic analysis of differences in genome-wide MAE patterns. In the outgoing phase of the Fellowship, I will be based in DFCI under the supervision of Prof. A. Gimelbrant. There, I will experimentally map MAE patterns in mice with highly divergent genomic backgrounds and identify loci that consistently differ between strains in whether they are MAE. Using computational methods, I will then determine whether particular motifs are associated with such variable regions. I will further assess the role of the candidate regulatory elements using specific F1 crosses and targeted mutagenesis. The analysis in the mouse will be complemented by comparative analysis of human and chimp matched cells, in order to narrow down the candidate loci list and shed light on the evolution of MAE. Successful completion of this project will establish the first model of genetic control of MAE and open doors to progress in the mechanistic and developmental understanding of MAE. On return to the TCD, under the supervision of Prof. A. McLysaght, I will be the link between two laboratories with a diverse research focus that would not be collaborating unless in the context of this Fellowship. I will emerge from this collaborative work with new skills commensurate with a leading independent researcher in the EU.
NOVEL COMPOSITE WEB

A multilayered nonwoven composite web (10) particularly useful as a substitute for a woven web such as a textile web, and having improved liquid wicking and retention properties comprising a first layer (12) of fibrous material selected from the group consisting of thermoplastic meltblown man-made fibers, thermoplastic spunbonded man-made fibers, thermoplastic man-made staple fibers and combinations thereof, this first layer being light weight, and a second layer (14) of cellulosic-based fibers, preferably cotton fibers, the first and second layers being thermally bonded (16) together over about 5 to 75% of the surface area of the web to form a coherent web having an air permeability of between about 25 and about 37 ft<3>/min/ft<2>. In a preferred embodiment, the composite web includes at least a third layer of thermoplastic man-made fibers and the layer of cellulose-based fibers is sandwiched between the two layers of thermoplastic man-made fibers.
28P Dose determination and pharmacokinetics (PK) of pralsetinib: Results from the phase I ARROW study

The phase 1/2 ARROW (NCT03037385) study supported approval of pralsetinib, a highly potent oral selective RET inhibitor, for RET-altered non-small cell lung cancer (NSCLC) in the US, EU, and other countries, and thyroid cancer (TC) in the US. Here we report data from the phase 1 dose-escalation part of ARROW. In phase 1, pralsetinib once daily (QD; 30–600 mg) or twice daily (BID; 200/100 mg or 100/100 mg) was assessed in advanced solid tumors (RET-altered for doses >120 mg per day). Key endpoints were maximum tolerated dose (MTD), recommended phase 2 dose (RP2D), safety (all primary); PK and overall response rate (ORR) (both secondary). At data cut-off (November 18, 2019), 60 of 62 patients enrolled in phase 1 were included in the dose-determining population (QD, n=51; BID, n=9); 2 who received <75% of study drug with no dose-limiting toxicities (DLTs) were excluded. Median age was 56.5 years (range 19‒85), 58% were male, and 61% had Eastern Cooperative Oncology Group Performance Status 1. Median time to maximum plasma concentration of pralsetinib was 2–3 hours at 30–600 mg QD. Mean plasma elimination half-life was 11–23 hours at 200–400 mg QD; steady state was reached with <3-fold accumulation, consistent with half-life and dosing frequency. Exposure at 400 mg QD sustained coverage above predicted 90% inhibitory concentration for RET in tumor and brain. ORR was 42% (95% confidence interval 15‒72) in 12 patients treated at 400 mg QD (RET-fusion positive NSCLC [n=3], differentiated TC [n=2], and medullary TC [n=6 RET-mutant, n=1 unknown mutation status]). DLTs occurred in 11 patients, including 2/4 at 600 mg QD (hypertension, hyponatremia), 2/12 at 400 mg QD (hypertension, myositis), 2/11 at 300 mg QD (hypertension, tumor lysis syndrome [TLS]), 2/4 at 200/100 mg BID (both hypertension), and 2/5 at 100/100 mg BID (hypertension, TLS). Based on safety and exposure, 400 mg QD was chosen as MTD and RP2D. Six patients discontinued due to treatment-related adverse events. Pralsetinib 400 mg QD was well tolerated, showed promising antitumor activity, and was chosen as the RP2D for the registrational phase 2 part of ARROW.
Counties of Romania in 1930

The dataset depicts the main administrative divisions of Romania (the counties/Ro. judeţe) in 1930. Main reference: Wilfried Krallert, Volkstumskarte von Rumänien: auf Grund der Ergebnisse der amtlichen rumänischen Zählung über die Volkszugehörigkeit von 1930 (Wien, 1940).
Establishing services enhancing the innovation management capacity of sme's in the enterprise europe network

Main task is to establish the services “Enhancing the innovation  management capacity of SMEs” within the Enterprise Europe Network with the intention to enhance SME’s potential in a successful result of their participation in The SME instruments project and to assist particularly promising SMEs in enhancing their innovation management capacities. The services are aimed at SMEs in Iceland with a great potential for international growth, but lack knowledge, skills or ability to manage innovation activities. Highly qualified staff of Enterprise Europe Network at the Innovation Center Iceland possesses the skills required and in-depth  knowledge of the support required to enable companies to reach their potential.
Effect of Container Size, Inoculum Density, and Test Duration on Detecting Resistance to Cylindrocladium Black Rot of Peanut

Abstract Cylindrocladium black rot (CBR), caused by the fungal pathogen Cylindrocladium parasiticum Crous, Wingfield, and Alfenas, is an important peanut (Arachis hypogaea L.) disease in the Virginia-Carolina and Southeastern U.S. production regions and was first confirmed in Texas in 2004. We refined a screening technique and compared disease assessment methods for CBR using peanut germplasm with known resistance levels. Resistant genotype ‘NC 3033’ and susceptible ‘NC 7’ were compared in a growth chamber using 66 and 164 cm3 container sizes, 15 and 25 microsclerotia/g soil inoculum densities, and 4, 5, and 6 week durations. Root rot ratings (0 to 5 index), percent taproot necrosis and percent secondary root necrosis were estimated. Taproot necrosis was the most reliable method for differentiating between the resistant and susceptible genotype, followed by root rot ratings. The use of secondary root necrosis ratings was less consistent for detecting differences than taproot ratings. Large containers (164 cm3) inoculated at the 25 microsclerotia/g soil density was the most reliable combination for attaining significant genotype differences for taproot necrosis and root rot ratings. The 5 week duration provided the most consistent results for taproot necrosis, while 6 weeks was the most reliable duration for root rot ratings. Percent taproot necrosis is a valid, more objective alternative to root rot index ratings.
PRODUKTVERPACKUNGEN

DAS PROJEKT BETRIFFT DIE REALISIERUNG VON VERPACKUNGEN UND KLEBEETIKETTEN FÜR DIE RÜCKVERFOLGBARKEIT DES PRODUKTS FÜR DIE LEBENSMITTEL- UND KÖRPERPFLEGE.   INSBESONDERE DIE SINCROMIA SRL BEABSICHTIGT, SICH AN KLEINE AGRAR- UND LEBENSMITTELERZEUGER ZU WENDEN, DIE IHNEN DIE MÖGLICHKEIT GEBEN, IHR PRODUKT IN KLEINEN, SEHR GENANNTEN LOSEN AUF NULL KM ZU VERPACKEN. BIS HEUTE GIBT ES KEINE MÖGLICHKEIT, DASS DIE VERPACKUNG DAS VORRECHT DER PAPIERKRAM IST, DIE AUFTRÄGE MIT G
Network of pioneering communities and regions working on innovative heat energy solutions

The availability of secure and efficient regional energy systems is an essential prerequisite for regional development, particularly for structurally weak regions. In its Green Paper on the Security of Energy Supply, the European Commission singled out heating as the largest energy sink that is mainly based on fossil and imported fuels. Municipalities play a key role, as they are suppliers of (district) heat as well as regulators, policy-makers, planners, investors, and consumers. Specifically, the New Member States and bordering regions with their extensive district heating systems face serious financial, technical and institutional problems. Major caveats include, fragmented decision-making structures, lack of coherent support policies for (district) heating and cooling and financing constraints. Overall objective / Objectif général The overall objective of “Regenergy - Network of Pioneering Communities and Regions Working on Innovative Heat Energy Solutions” is to contribute to a secure, environmentally sound, and affordable provision of heat energy. Partners from ten countries aim at creating an interregional support and information network of regional and local authorities, utilities, universities, energy agencies, and regional development agencies to promote the exchange of experiences and to identify, disseminate and encourage best practices in core areas such as innovative policy approaches and financing. Expected results / Résultats attendus The operation increases the capacities of municipal and regional decision-makers to promote energy efficiency and security of supply of heat energy. It provides dissemination of practical information, supports authorities in the identification of investment potentials in heating systems, in the diversification of energy sources, and in the development of projects eligible under EU Structural Funds. In the long run, the operation promotes energy efficiency and a more effective use of Structural Funds and contributes to regional development and the mitigation of social disparities. Activities include policy assessments and the elaboration of policy and methodological guidelines for municipal decision-makers. Partners also collect and document good practice cases, develop a financial evaluation framework and make concrete proposals for projects and financing possibilities. Based on thematic workshops and seminars with potential multipliers and investors, partners identify two to three pilot projects and conduct related (pre-) feasibility studies.
Model reduction by moment matching for linear switched systems

Two moment-matching methods for model reduction of linear switched systems (LSSs) are presented. The methods are similar to the Krylov subspace methods used for moment matching for linear systems. The more general one of the two methods, is based on the so called "nice selection" of some vectors in the reachability or observability space of the LSS. The underlying theory is closely related to the (partial) realization theory of LSSs. In this paper, the connection of the methods to the realization theory of LSSs is provided, and algorithms are developed for the purpose of model reduction. Conditions for applicability of the methods for model reduction are stated and finally the results are illustrated on numerical examples.
Patterns of 6-mercaptopurine and azathioprine maintenance therapy among a cohort of commercially insured individuals diagnosed with Crohn&#39;s disease in the United States

Thiopurines, including 6-mercaptopurine (6-MP) and azathioprine (AZA), are the mainstay of maintenance therapy for Crohn's disease (CD). However, studies examining their effectiveness in routine practice among diverse patient populations are lacking. Among a cohort of new users of 6MP/AZA, we described treatment patterns and changes in subsequent therapy.Using the Truven Health Analytics databases, we identified all individuals diagnosed with CD and initiating 6-MP/AZA monotherapy from 2001-2008 (n=3,657). We estimated the proportion of CD patients remaining on 6-MP/AZA monotherapy, using Kaplan-Meier methods, and identified predictors of treatment noncontinuation, using multivariable Cox regression. Among the "noncontinuers," we described subsequent patterns of maintenance therapy and summarized the diagnosis and procedure codes and prescription drug claims preceding treatment discontinuation.The 1-year 6-MP/AZA treatment continuation rate was 42%. Children (age ≤18 years) and individuals with no prior anti-tumor necrosis factor (TNF) use were more likely to continue 6-MP/AZA, while those dispensed more (>4) outpatient prescriptions for any drug before initiation of 6-MP/AZA were less likely to continue maintenance treatment. Overall, 1,128 (39%) and 105 (4%) individuals experienced a clinical event potentially indicating active disease or 6-MP/AZA-intolerance prior to discontinuation, respectively. Most patients discontinued therapy; among the remaining patients who failed to continue 6-MP/AZA, most augmented with an anti-TNF.Most patients initiating 6-MP/AZA monotherapy did not continue beyond 1 year. In contrast to trial evidence showing 1-year remission rates of 40%-80%, this study observed a lower effectiveness of 6-MP/AZA treatment, possibly due to differences in disease severity, patient demographics, comorbidity, adherence, and health care utilization.