SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Unique biomaterial-drug solution for multifunctional central venous catheters

Central venous catheters (CVCs) play a critical role in healthcare and few medical devices are more important and widespread in modern medicine. Catheter-related bloodstream infection (CRBSI) is the most common life-threatening complication of CVCs. Reducing the risk of CRBSI among patients would save costs, reduce length of stay and improve mortality and morbidity. 
The major challenge of UNICAT is thus to develop a new CVC solution to prevent infection and thrombosis. The project partners will introduce a whole new way of thinking by introducing a disruptive approach which is more than just a coating of devices. A new material will, for the first time, combine ultra-biocompatibility with chemical resistance and desired mechanical properties, to effectively prevent adverse host response, inflammation and infection. A major problem in biomaterials science is that bioresistant materials are inevitably also chemically inert and hence highly difficult to manipulate by traditional wet chemistry. If manipulation (e.g. coating) is achieved, the solution is often unstable and fragile. UNICAT will address this problem by combining two materials using a novel method based on super critical CO2-chemistry. It will result in a hybrid material which is stably formed and combines the best properties of two or more materials.
The success criterion is to exceed performance of coatings by producing the first fully biocompatible material to be used as sole robust bulk material of vascular access lines.
UNICAT is an international and inter-sector collaborative project comprising R&D activities and secondments between the SME BioModics (BM), the University of Minho (UMinho), the Bar-Ilan University (BIU) and the Simula Research Laboratory (Simula). The consortium has identified the RISE programme as a suitable vehicle for overcoming the identified major challenges and for bridging the knowledge gap, while helping to overcome the financial, technological and intersectoral barriers.
Loss of Correction in the Treatment of Thoracolumbar Kyphosis Secondary to Ankylosing Spondylitis

Retrospective comparison of database patients.To evaluate the difference of loss of correction between Smith-Petersen osteotomies (SPOs) and pedicle subtraction osteotomy (PSO) in patients with thoracolumbar kyphosis secondary to ankylosing spondylitis (AS).SPOs and PSO are reported to be the 2 major techniques for correction of thoracolumbar kyphosis resulting from AS. Previous studies have tried to compare the indication, technical aspects, correction obtained, and complication rates between the aforementioned 2 techniques. However, reports addressing a comparison of loss of correction between SPOs and PSO are limited.On the basis of the types of osteotomies, 50 patients were divided into 2 groups: (1) SPOs group (n=19) including 16 male and 3 female patients, with an age range from 21 to 40 years (mean 27 y). The preoperative global kyphosis (GK) ranged from 41 to 99 degrees (average 64.6±25.6 degrees); (2) PSO group (n=31) consisted of 26 male and 5 female patients, with an age range from 22 to 54 years (mean 36 y). The preoperative GK was 50 to 96 degrees (average 73.7±23.6 degrees). Radiographic parameters including sagittal vertical axis, T12-S1 lordosis, GK, and angle of fusion levels were measured.Both groups showed similar preoperative and postoperative thoracic kyphosis, lumbar lordosis, and sagittal vertical axis. The average GK was corrected to 25.5 degrees and 31.4 degrees in SPOs group and PSO group, respectively. All cases were followed for a minimum of 2 years. At the last follow-up, mean loss of correction in the fusion levels were 6.1 degrees in SPOs group and 1.3 degrees in PSO group, respectively. The difference was statistically significant (P=0.034). Loss of correction of >5 degrees occurred in 4 cases (21.1%) in SPOs group, and 5 cases (16.1%) in PSO group.Both SPOs and PSO showed similar effect in correcting the thoracolumbar kyphosis secondary to AS. However, patients treated with the SPOs technique showed higher risk in loss of correction in the instrumented region.
Point-of-Care Ultrasound in General Practice: A Systematic Review

Ultrasound examinations are currently being implemented in general practice. This study aimed to systematically review the literature on the training in and use of point-of-care ultrasound (POCUS) by general practitioners.We followed the Cochrane guidelines for conduct and the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines for reporting. We searched the databases MEDLINE (via PubMed), EMBASE, CINAHL, Web of Science, and Cochrane Central Register of Controlled Trials using the key words ultrasonography and general practice in combination and using thesaurus terms. Two reviewers independently screened articles for inclusion, extracted data, and assessed the quality of included studies using an established checklist.We included in our review a total of 51 full-text articles. POCUS was applied for a variety of purposes, with the majority of scans focused on abdominal and obstetric indications. The length of training programs varied from 2 to 320 hours. Competence in some types of focused ultrasound scans could be attained with only few hours of training. Focused POCUS scans were reported to have a higher diagnostic accuracy and be associated with less harm than more comprehensive scans or screening scans. The included studies were of a low quality, however, mainly because of issues with design and reporting.POCUS has the potential to be an important tool for the general practitioner and may possibly reduce health care costs. Future research should aim to assess the quality of ultrasound scans in broader groups of general practitioners, further explore how these clinicians should be trained, and evaluate the clinical course of patients who undergo scanning by general practitioners.
Vecteurs contribuant aux redéfinitions politiques de l’époque révolutionnaire, les femmes et hommes étrangers participent pleinement à la construction d’une cité nouvelle, par des interactions culturelles continues, ainsi que par le biais de leur engagement individuel. Ce numéro interroge ainsi à nouveaux frais le croisement et l’influence entre différents modèles révolutionnaires. Envisager des trajectoires individuelles comme collectives permet de mieux saisir la dialectique à l’œuvre entre la contribution que les étrangers ont apporté au déroulement de la lutte politique nationale et la manière dont les institutions ont géré leur présence, tout en cherchant à décentrer le regard et à questionner cette problématique dans un contexte européen et atlantique. As vectors contributing to the political redefinitions of the revolutionary era, foreign men and women fully participated in the construction of a new city through continuous cultural interactions as well as through their individual commitment. This issue thus takes a fresh look at the intersection between and influence of different revolutionary models. Looking at both individual and collective trajectories allows to better grasp the dialectic at work between the contribution that foreigners made to the unfolding of the national political struggle and the way in which institutions managed their presence, while seeking to broaden the focus of the observation and to tackle this question in a European and Atlantic context.
Suppression of Harmonics in Microstrip Filters Using a Combination of Techniques

Existing and newly adapted techniques for suppressing harmonic responses in microstrip filters were combined. Stagger tuning using additional stubs to shift the resonances has been adapted to quarter-wave resonators and extended to the seventh-order spurious response. Suitable resonator overlap provided transmission zeroes to cancel spurious peaks. Coupling capacitor pads acting as shorting stubs have been developed. Spurious responses were suppressed to better than $-{\hbox{33 dB}}$ , up to 6.3 GHz, in a measured filter with 1-GHz center frequency and 42% bandwidth. Suitably placed resistors have depressed the spurious level further to $-{\hbox{50 dB}}$ up to 5.6 GHz, with only 0.07-dB extra passband loss.
Knowledge, perception, and the art of camouflage

I present a novel argument against the epistemic conception of perception (ECP) according to which perception either is a form of knowledge or puts the subject in a position to gain knowledge about what is perceived. ECP closes the gap between a perceptual experience that veridically presents a given state of affairs and an experience capable of yielding the knowledge that the state of affairs obtains. Against ECP, I describe a particular case of perceptual experience in which the following triad of claims is true: (i) The experience presents a given state of affairs (it has propositional content); (ii) The experience is veridical; (iii) The experience cannot yield the knowledge that the state of affairs obtains (even in the absence of relevant defeaters). This case involves an empirically well-studied phenomenon, namely perceptual hysteresis, which involves the maintenance of a perceptual experience with a relatively stable content over progressively degrading sensory stimulations.
A new technology of microthermal sensing for application in microcalorimetry

ANTS aims to prove the viability of a novel thermal microsensor, with highly improved thermal, temporal and spatial resolution, to be the basis of a breakthrough micro/nano-calorimeter. The resulting device shall quantify binding rates and enthalpy/entropy changes in interactions of biological interest in a much more accurate and straightforward manner than available techniques. Consequently, ANTS-microcalorimeter will facilitate enormously drug discovery and development of biomedical products and technologies. We propose to exploit the large Nernst effect in ferromagnetic conductors for electrical sensing of temperature gradients with exceptional sensitivity. The active sensing elements are composed of a single material, thus offering important advantages for miniaturization over conventional micro-calorimetry, based on diverse Peltier modules, whereas easy to fabricate by standard, scalable deposition and photolithographic methods. Standard microcalorimeter configuration can also be maintained in the novel device, which is convenient to ensure compatibility and foster adoption by users and manufacturers.
Revisão Sistemática sobre a Produção Científica do Programa Esporte e Lazer da Cidade

O objetivo foi analisar a produção científica sobre o Programa Esporte e Lazer da Cidade (PELC) por meio de uma revisão sistemática qualitativa. Os resultados demonstraram que um grupo de pesquisadores concentrados nas regiões Sul e Sudeste, estão impulsionando as publicações sobre o PELC em periódicos predominantemente da área de Educação Física e Lazer. Existe uma concentração de pesquisas em gestão, formação e avaliação com ênfase nas diretrizes e na concepção de lazer do programa. De forma secundária, foi reportado pesquisas em financiamento, marcadores sociais e temas transversais. Para investigações futuras, destaca-se a necessidade de pesquisas com maior pluralidade metodológica e teórica, que ultrapasse as pesquisas descritivas, com abordagem qualitativa.
The Piave river eastbound flow: tourist-cultural itineraries.

The current project stems from the need to enhance the territory of Noventa di Piave through the organization of several activities connected to the territory: the main objective consists in fostering local tourism through thematic events related to the environment and tourism. To this end an “Environment Day for mutual hospitality” is organised to offer didactic activities for the students of Slovenian schools visiting Noventa. They are thus actively involved in the discovery of the local environment and territory; the host schools function as guides, by taking their guests to the Piave river and the itineraries that have been organized by the project. The day devoted to the “River Theatre” offers theatre and musical performances by local groups working from partner areas, while the “Living Crib” focuses on dialogue and learning about other peoples. The result pursued is the national, cross-border and international promotion of the local territory. A tourist guide will also be prepared entitled “From Piave to the East”, as well as other didactic material, a promotional CD-ROM and tourist-cultural itineraries set up by the project, lastly information brochures will be published to present the activities and the goals of the project.
Quantitative paleoenvironments from speleothems

Speleothems (cave deposits, e.g. stalagmites) represent unique terrestrial archives that allow for accurately dated, high-resolution (often annual), continuous and long (many millennia) climate reconstructions. Such records are vital for understanding how climate varies and how our environments respond on seasonal to millennial timescales. However, current speleothem studies can only make qualitative inferences about climate parameters – i.e. they can tell us the direction of change (warmer, drier, etc.) but not the amount of change (how warm? how dry?). Quantitative information is crucial to make speleothem-based data more useful to climate modellers and policy makers.
QUEST (QUantitative palaeoEnvironments from SpeleoThems) will develop new techniques for extracting quantitative information from speleothems and link field and laboratory experiments on water/mineral chemistry with innovative physical and numerical analyses on speleothems. The combination of these techniques, based on physical and chemical properties and statistical methods, will allow us to deliver quantitative reconstructions of two key parameters: hydrology and temperature. We will test our methods using speleothems from Australasia, a region vulnerable to El Niño-Southern Oscillation (ENSO) variability. At present, there is a relative dearth of millennial-scale palaeoclimate data from this region.
Our team members come from a variety of backgrounds including environmental chemistry, environmental mineral magnetism, and numerical data analysis. Each group within the team has already begun developing innovative methods for palaeoclimate reconstruction within their own subfield, but this project will be the first time these methods are combined and applied collectively to speleothems. Our combination of interdisciplinary expertise, state-of-the-art instrumentation, and novel techniques means that we are ideally placed to develop quantitative climate records from speleothems.
The effect of protein concentration and heat treatment temperature on micellar casein–soy protein mixtures

Abstract The objective of this study was to investigate the effect of concentration and temperature on the rheological properties of soy proteins (SP) and micellar casein (MCN) systems. Individual and mixed (1:1) protein systems of 2–15% concentration were prepared and heat treated for 5 min at 40–90 °C. After cooling to 20 °C, their rheological properties were determined using steady-shear rheology. Zeta potential and particle size measurements were also conducted. Both proteins were negatively charged under all experimental conditions, but the absolute values of zeta potential and thus the stability of the protein solutions decreased with temperature and concentration. For SP solutions, viscosity and apparent yield stress increased with concentration. Shear thinning behavior was prevalent, becoming more pronounced with increasing concentration. Heat treatments at T  ≥ 80 °C induced glycinin denaturation, followed by aggregation and network formation when C  ≥ 7.5%. Heat treatment did not significantly affect viscosity of MCN systems, while increasing concentration resulted in a significant increase in apparent viscosity and apparent yield stress. Most MCN systems exhibited Newtonian flow behavior, with the exception of systems with C  ≥ 12.5% treated at T  ≥ 80 °C, which became slightly shear thickening. Mixed SP–MCN systems mimicked the behavior of SP, with most values of rheological parameters intermediate between SP and MCN-only systems. Mixtures of 7.5–12.5% concentration treated at 90 °C displayed local phase separation, low viscosity and apparent yield stress, while 15% mixtures treated at 90 °C showed protein aggregation and incipient network formation. The data generated in this study can be used to develop a range of protein based products with unique flow characteristics and storage stability.
Study on differences of colorimetric between Yin Zheng and Yang Zheng jaundice in patients with hepatogenic jaundice

Objective: To study the data of facial complexion in hepatogenic jaundice which were detected by optical spectrum colorimetry,and analyse the differences of colorimetric between Yin Zheng and Yang Zheng jaundice.Methods: Facial complexion data from 268 eligible hepatogenic jaundice patients were collected and divided into Yin Zheng and Yang Zheng jaundice groups according to the feature of the clinical classification.The distribution in the CIE LAB uniform color space were observed,and the difference of overall colorimetric,clarity,chroma,saturation and tone were analysed.Results: There were different distribution area of the facial complexion between Yin Zheng and Yang Zheng jaundice groups in the CIE LAB color threedimensional space,while the values of L* of Yang Zheng jaundice were higher than that of Yin Zheng jaundice(P 0.001).The difference of overall colorimetric on tip of the nose and forehead were 9.98 and 5.82 error of chromatic units,with the largest value clarity.Conclusion: There is obvious differences of colorimetric between Yin Zheng and Yang Zheng jaundice groups,which are consistent with the characteristic in clinical,and could be the reference for TCM syndrome classification in jaundice.
Promoting Innovation in the Industrial Informatics and Embedded Systems Sectors through Networking

The industrial informatics and embedded systems sectors present leading edge technology sectors that provide a competitive advantage for Europe. The SEE area is mostly characterized by developing low-wage based economies that will face a need for change in the near future. In order for these economies to be competitive in the globalised economy, focus should be placed on their transformation to knowledge-based innovation-driven economies. I3E addresses this problem through the creation of a transnational partnership comprising 12 partners from 8 different countries. The project will develop a Strategic Research Agenda in the aforementioned technological sectors that will make it possible to align research efforts in the area so that a significant critical mass is created. This SRA will be a result of a wide consensus building among the different stakeholders in the area, comprising academia, industry, the public sector, facilitators of innovation, such as clusters, technology platforms, existing networks of excellence as well as private financing mechanisms, developed through a wide transnational network in the area. It will thus be in line with the local / regional / national strategies in the area while synergies will be sought to similar initiatives at a European level. Nevertheless, research is not sufficient in an area; it should be transformed to innovation in order to give back to the community advanced products and services that will help increase competitiveness. I3E will create a methodological guideline on innovation showcasing how this transformation is possible utilizing international best practices for this purpose. The main project outputs SRA and MGI will be widely disseminated towards the enterprise world and the general public, while capacity building activities will be also undertaken towards the entrepreneurial world. The active involvement of policy makers will result in the influence of regional strategies in the area.
Waste-rock hydrogeology and geochemistry

Abstract The oxidation of sulfide minerals in waste rock has the potential to generate low-quality drainage that can present a significant challenge to mine owners, regulators, and other stakeholders. Challenges involved in managing waste rock include the large volume of waste rock produced and the difficulty in predicting the quality and quantity of leach water due to the chemical and physical heterogeneities in the waste rock, and the highly non-linear coupling of geochemical and physical processes. Many important studies have been conducted over the past decade, particularly at the field scale, that have investigated the geochemical, hydrological, microbiological, and gas and heat transport aspects of waste-rock. These studies show that although the parameters and processes that influence AMD generation and solute release are fundamentally similar between different waste-rock piles, major differences in the dominant mechanisms of water, gas and heat transport result from differences in the physical and mineralogical properties of the rock piles, and the climatic conditions, including the amount of precipitation and prevailing temperatures. Accurate prediction of the leach water quality from waste-rock requires a detailed characterization of the properties of the rock piles and the coupling of processes specific to the particular conditions. This paper provides a review of the physical and mineralogical characteristics of waste-rock piles, followed by a discussion of the principal processes related to sulfide oxidation and solute loading, and concluding with a discussion on acid mine drainage prediction and prevention techniques.
GAS TURBINE VANE

The invention relates to a gas turbine vane, especially a vane pertaining to an aircraft engine, comprising a blade (11) and a vane footing (12). Said blade (11) is defined by a flow inlet edge or a front edge (13), a flow outlet edge or a rear edge (15), and a blade surface (15) extending between the front edge (13) and the rear edge (14) and forming a suction side (16) and a pressure side (17). According to the invention, the suction side (17) of the blade (11) comprises at least one microprofiled or microstructured region (18; 20, 21, 22) for optimising the flow around the blade (11).
Periosystem – smart dental practice management software

The European dental profession is yet to embrace the full potential of technological advances. Dentists rely on outdated software systems to manage their practices, take clinical notes, analyze images and communicate with patients. Administrative tasks take up to 20% of a practitioner’s time, which could be more productively spent on treatment and diagnosis.
PerioSystem is the only integrated cloud-based dental management software system that combines the functionalities of five dental software services: practice management; patient communication; treatment planning; patient education; and accounting. It also introduces four major technology advances to clinical dentistry: (i) voice recognition; (ii) motion recognition; (ii) facial recognition; and (iv) augmented reality. This seamless bundling of technologies places PerioSystem far ahead of competitive solutions, which offer only partial services.  
Early tests show PerioSystem can reduce administrative time from 20% to 11%, increase diagnostic time by up to 10%, and eliminate 60% of missed appointments. This would lead to an annual benefit of at least €13,860 for the average dentist, or 14.9% of average revenues. 
PerioSystem uses a B2B SaaS model with tiered monthly fees. It targets the 213,276 practicing dentists in Europe and 210,030 in the United States.
The company aims to capture 5% of the French market, and 0.5% in Germany, Italy and the UK by 2020, resulting in €7.6M revenues and €1.M EBIT. Sales campaigns utilize high-profile endorsements, co-operation with professional societies, and free tools for student dentists. Already more than 100 pre-orders have been collected.
The tool is developed by Adservio SARL, a French software development company led by Mr. Anis Zouaoui, an experienced software engineer and entrepreneur, and Dr. Wiem Bouaziz, a practicing periodontist.
The system will soon be tested by 59 practitioners in 21 clinics in France and Germany.