SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Correlation Between Reduction of Seclusion and Restraint and Assaults by Patients in Pennsylvania’s State Hospitals

Objective: This prospective study assessed the use of seclusion and restraint in the Pennsylvania state hospital system from 2001 through 2010. It also examined the correlation between declining use of containment procedures and assaults by patients on other patients and staff. Methods: The 12,900 anonymized records involving the 1,801 unique, civilly committed individuals who were physically or mechanically restrained and secluded in the nine civil hospitals during this study period were entered into a database. The data set included demographic and diagnostic information about the patients and the cause and effect of the procedures. These data were compared with rates of patient-to-patient and patient-to-staff assaults to determine any correlation between changes in use of containment and assaults. Results: From 2001 to 2010, the use of mechanical restraint significantly declined from .37 to .08 episodes per 1,000 days (p<.018), and the use of seclusion significantly declined from .21 to .01 episodes per 1,000 days (p<.001). Persons with an axis I diagnosis of psychotic disorder accounted for 44% of containment procedures used during this study. Patient-to-patient assaults declined slightly, and patient-to-staff assaults were unaffected. Conclusions: Decreasing the use of containment procedures did not increase assaults. Better leadership, data transparency, use of clinical alerts, workforce development, policy changes, enhanced use of response teams, implementation of dialectical behavior therapy, and discontinuation of the psychiatric use of PRN orders contributed to the change in use of containment procedures. A philosophical change to a recovery model of psychiatric care and services was the driving force behind this transformation.
Acyclic 4-choosability of planar graphs

A proper vertex coloring of a graph G = ( V , E ) is acyclic if G contains no bicolored cycle. Given a list assignment L = { L ( v ) ∣ v ∈ V } of G , we say G is acyclically L -list colorable if there exists a proper acyclic coloring π of G such that π ( v ) ∈ L ( v ) for all v ∈ V . If G is acyclically L -list colorable for any list assignment with | L ( v ) | ≥ k for all v ∈ V , then G is acyclically k -choosable. In this paper we prove that planar graphs without 4, 7, and 8-cycles are acyclically 4-choosable.
Odyssea Corsica, Liguria, Toscana, Sardegna

The project Odyssea looks at the sea as a unifying opportunity, which cancels the effects of border cooperation to support high value added. It also aims to (a topic that will be the subject of the strategic plan) to reposition the cross-border area as a tourist destination, boating, European excellence. The project involves the creation of a network of ports - City Territories based on a story and goals.
The space of reference: The project involves the totality of the space program. The simple project will test the concept Odyssea in four regions and 15 cities in the laboratory.
The overall goal: to experience the city in the pilot model of sustainable development and management, Odyssea, in order to improve the services offered and the network of marinas in the making and neighboring territories. This development model will be tested from a joint regulation, a transferable methodology, innovations introduced to create a network of cross-border offerings through new communication technologies. The concept integrates land compulsorily, the sea, the harbor, the city built in rural areas. The project is structured according to an environmental ethics of offerings and services related to the four major themes Odyssea.
The target of the project are of different types: the inhabitants of the territory during the collection of data on the attractors of the territory, the sector of tourism and recreational boating, residents, tourists, boaters, but also the local managers ports of natural and cultural attractions, the marine workers, farm and enotourism private and public.
The project Odyssea will run for 27 months and a total budget of EUR 2,414,100.00 and plans to develop laboratory the following activities: animation project based on the concept of tourism the second of the four themes of Sea and Land tour , pilot activities in the fields of tourism and environment, organization of joint events.
Enhanced depressive-like behaviors after Toll-like receptor 7 stimulation in mice.

Toll-like receptor (TLR) 7 recognizes viral single-stranded RNA and triggers anti-viral immune responses through the production of type I interferons (IFNs) IFN-alpha and IFN-beta. IFN-alpha is known to induce various psychiatric changes such as depressive symptoms; however, the correlation with TLR7 activation remains to be determined. In this study, we examined the effect of imiquimod, a TLR7 specific ligand, on depressive-like behaviors evaluated by the forced swim test (FST) and the tail suspension test (TST) in mice. Immobility durations were significantly prolonged in both FST and TST by 2 h after imiquimod treatment (50 microg/body, i.p.), indicating that TLR7 activation enhanced depressive-like behaviors in mice. In addition, imiquimod induced IFN-alpha mRNA expression in the hippocampus, whereas it prevented long-term potentiation in the Schaffer-CA1 pathway (i.e., hippocampal synaptic plasticity). Moreover, TLR7 mRNA expression in the hippocampus was higher than that in the whole brain. These findings suggest that TLR7 activation enhances depressive-like behaviors in mice, possibly through increasing IFN-alpha expression and altering synaptic plasticity in the hippocampus.
GLP-2 COMPOUNDS, FORMULATIONS, AND USES THEREOF

The present invention relates to novel human glucagon-like peptide-2 (GLP-2) peptides and human glucagon-like peptide-2 derivatives which have a protracted profile of action as well as polynucleotide constructs encoding such peptides, vectors and host cells comprising and expressing the polynucleotide, pharmaceutical compositions, uses and methods of treatment.
ELECTRONICS ENCLOSURE WITH HEAT-TRANSFER ELEMENT

A compressor may include a compressor shell, a motor, a compression mechanism, and an assembly that houses an electronic component. The electronic component may control operation of the compressor and/or diagnose compressor faults. The assembly may include a shell, an electronic component, a fan, and an airflow deflector. The shell member may define an enclosure having an internal cavity. The fan and the electronic component may be disposed within the internal cavity. The airflow deflector may include a base portion, a first leg, and a second leg. The first and second legs may be spaced apart from each other and extend from the base portion. The fan may force air against the base portion. A first portion of the air may flow from the base portion along the first leg. A second portion of the air may flow from the base portion along the second leg.
RECYCLABLE POLYMERIC SYNTHETIC PAPER AND METHOD FOR ITS MANUFACTURE.

Un papier synthétique sans cellulose et fortement opaque (58) est formé à partir d'une bande non tissée de fibres thermoplastiques (44) posée par voie humide, tout ou partie des fibres étant constitué d'un matériau polymère prédéterminé. La bande posée par voie humide est séchée pour éliminer l'eau en excès (46), le séchage (48) s'effectuant à des températures inférieures à la température de fusion du matériau polymère prédéterminé. La bande non tissée séchée est saturée sur au moins une face avec un liant pigmenté (50) y formant un revêtement continu. Ce liant est durci à des températures inférieures à la température de fusion (54) du matériau polymère prédéterminé.
Optimising radiomics for mri-based personalised cancer treatment

Although cancer survival rates have substantially improved in recent years, cancer is still among the leading causes of morbidity and mortality worldwide. The future of cancer treatment lies in early and better diagnosis and individually tailored treatments (‘personalised medicine). ptTheragnostic, a company dedicated to the development of more effective, individualised therapies for cancer patients, is working on a breakthrough solution, Radiomics, that is able to revolutionise personalised cancer treatment. Radiomics is a quantitative image analysis technology that enables patient stratification through the use of routinely acquired biomarkers. Being based on the evolution of hundreds of image-derived features over the course of treatment, Radiomics allows for more sensitive and robust identification of tumour types than currently possible. As MRI is recognised as one of the most promising techniques for the detection of cancer and spread of the disease, ptTheragnostic aims to align Radiomics with MRI. Despite the availability of a multi-disciplinary team at ptTheragnostic, they lack the required expertise and skills to implement Radiomics in the MRI market. Therefore, the goal of this project, REACT, is to hire a skilled associate with expertise in MRI and deep learning to establish this implementation. 
During the first 12 months, the associate will be responsible for managing the designed innovation track of Radiomics. This includes both technical and business tasks, amongst aligning the Radiomics software with MRI scanners and drafting a marketing strategy for Radiomics. The associate will follow various trainings in the oncology and business field. REACT may therefore open up new career possibilities in both the business and academic (oncology) field. In addition, REACT, will leverage the growth of ptTheragnostic by enabling Radiomics for MRI resulting in a significant increase in revenues (additional 50% in the first year) and increase in FTE (33%).
Self-Healing on natural hydraulic lime mortars

Most of the civil and architectural heritage is built with masonry structures. The interventions on such structures require the usage of compatible materials such as natural hydraulic lime (NHL) mortars that offer a promising solution due to their large compatibility with original materials in terms of chemical, physical and mechanical performance. Furthermore, these interventions demand to be as durable as possible and in this sense, the self-healing capacity of NHL mortars seems to be of potential value.   HeaLime will create a new testing method to measure self-healing in cementitious materials. It will also characterize systematically a combination of several variables in the context of the performance of the healing capacity. The project will be performed mainly at University of Minho, Portugal, under the supervision of Prof. Lourenço, one of the most prestigious researcher in masonry components and Dr. Azenha, whose proposed methodology of EMM-ARM has involved a revolutionary step in the characterization of the stiffness evolution of cementitious materials. For the purpose, a new testing method will be developed by adapting the technique of EMM-ARM to the measurement of self-healing of NHL mortars in service. At the same time, different materials (such as micro-fibres, crystalline admixtures and superabsorbent polymers) will be combined to create improved NHL mortars for self-healing. Moreover, two secondments will be performed. The first one at University of Ghent, with Prof. De Belie, a leading specialist on self-healing materials, and at Kerakoll, a non-academic institution devoted to the commercialization of sustainable building materials. Finally, a series of pilot demonstration tests will be approached to study the applicability of such improved NHL mortars to building sites.   HeaLime will redound in more sustainable and durable repairing operations when approaching the different interventions of the civil and architectural heritage.
Subvention de fonds de roulement pour l’entreprise de construction industrielle PRZEM-BUD Société à responsabilité limitée

Le projet concerne le soutien de l’entrepreneur à fournir des liquidités financières et à soutenir les activités en cours en raison des difficultés financières rencontrées par l’entrepreneur à la suite de la pandémie de COVID-19. Assistance financière fournie au titre du programme SA.57015 (2020/N)
The geomagnetic field intensity in New Zealand: palaeointensities from Holocene lava flows of the Tongariro Volcanic Centre

Very few absolute palaeointensity data exist from Holocene-aged rocks in New Zealand. Here we present a new suite of high-quality palaeointensities, supported by detailed rock magnetic investigations. Samples from 23 sites representing 10 distinct eruptive units of the Tongariro Volcanic Centre, Taupo Volcanic Zone, New Zealand, were studied. Both traditional double heating and microwave palaeointensity methods were employed. The reliability of the palaeointensity data varies with rock magnetic properties of the samples, corresponding, in particular, to their positions within the lava flows. The highest success rates are from samples obtained from near the flow tops where a significant proportion of the remanence unblocked at intermediate temperatures (200-350 °C). By contrast, samples from flow centres, particularly the parts showing platey fracturing, have the lowest success rates. Reliable, high-quality palaeointensity results ranging from 32.4 ± 5.1 μT to 72.1 ± 4.7 μT were obtained from six flows with ages between c. 12 800 yr BP and the present. These correspond to virtual dipole moments that increase from 52 ± 10 ZAm2 in the early Holocene and peak at 112 ± 14 ZAm2 about 300 yr ago. The data agree well with calibrated relative palaeointensities from New Zealand lake sediments. The volcanic and sedimentary data together yield a Holocene virtual axial dipole moment curve that fits the global average variation well in the early Holocene, but which differs significantly in recent millennia. This difference is associated with recent migration of the southern high latitude core-mantle boundary flux lobe towards New Zealand, as is seen in global field models. (Less)
Laminate wall structure

A laminate wall structure which can be used as an exterior wall in manufactured housing and site built construction is made up of a low density layer having a density of from about one-half pound to three pounds per cubic foot, a second, reinforcing layer laminated to the low density layer and, optionally, a cellulosic layer laminated to the second, reinforcing layer. The low density layer is preferably a foamed polymer layer, the second, reinforcing layer is a polymer fabric, a biaxially oriented polymeric film or a fiberglass reinforced material and the cellulosic layer can be impregnated with an adhesive and/or resin in order to strengthen the laminate structure. This laminate wall structure has a low weight and yet is strong enough to meet wind zone wall diaphragm requirements for housing construction.
Yellowstone wolf (Canis lupus) density predicted by elk (Cervus elaphus) biomass

The Northern Range (NR) of Yellowstone National Park (YNP) hosts a higher prey biomass density in the form of elk (Cervus elaphus L., 1758) than any other system of gray wolves (Canis lupus L., 1758) and prey reported. Therefore, it is important to determine whether that wolf–prey system fits a long-standing model relating wolf density to prey biomass. Using data from 2005 to 2012 after elk population fluctuations dampened 10 years subsequent to wolf reintroduction, we found that NR prey biomass predicted wolf density. This finding and the trajectory of the regression extend the validity of the model to prey densities 19% higher than previous data and suggest that the model would apply to wolf–prey systems of even higher prey biomass.
Silica Mesostructures: Control of Pore Size and Surface Area Using a Surfactant-Templated Hydrothermal Process

The cooperative self-assembly of the silica precursor, tetraethyl ortho silicate (TEOS), with the surfactant molecule followed by the basic hydrolysis led to the formation of mesoporous silica with varying pore sizes. The pores are formed by the removal of the intermediate assemblies of the charged surfactant molecules. In the absence of formation of such assemblies of surfactants (example in the case of nonionic surfactants), the resulting mesostructures have very small pores, giving low surface area mesostructures. This study outlines the precise control of pore size in a wide size distribution (3.4-22 nm) by the systematic variation of the surfactant. The addition of polyethylene glycol (in situ) while carrying out the hydrolysis of TEOS results in the formation of large-sized cavities (∼40 nm). Uniform spherical particles with pores (different from the cavities) as large as 22 nm and surface areas of ∼1100 m(2)/g have been obtained by the combined effect of the hydrothermal conditions on the cetyl trimethyl ammonium bromide-templated synthesis.
Boost Environmental Guardianship for Inclusion

BEGIN will define models for creation and management of social start-ups finalized to the inclusion of disadvantaged people. Marginalized groups – e.g. unemployed, women, young people, immigrants, disabled, ex-convicts, former drug addicts - are counting significant percentage in every partner country._x000D_
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Innovative feature and main objective of Begin is the creation of tools to encourage the creation and development of social start-ups active in safeguarding of environmental protection for social work inclusion and employment of disadvantaged people, which then contribute to improvement of territories both for use citizens and tourists._x000D_
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BEGIN will transfer know-how from more innovative and experienced regions to those lagging behind creating an innovative model that can be transferred also to other regions not involved in the project._x000D_
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Main common challenge tackled regards environmental protection, also to promote tourism development. This challenge is faced through joint analyse of territorial frameworks to identify work activities at the base of social start-ups models and business models that are involving specifically marginalized groups._x000D_
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Non-profit and third sector organizations are an efficient tool for environmental protection, but are not very developed and structured in project countries, except for Italy. Hence, the project will capitalise results of research conducted in Italy by providing specific know-how._x000D_
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Direct project beneficiaries of milestones, outputs and deliverables will be the FACILITATORS OF SOCIAL START-UPS._x000D_
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Indirect beneficiaries will be potential social start-uppers, people with disadvantage employment, employees of social start-ups, research and innovation centres, training centres and employment agencies, as well as legal and relevant public authorities in every country._x000D_
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They also will lay the foundation for the creation of an INTERNATIONAL FACILITATORS NETWORK._x000D_
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This represent the main project output together with a TRANSNATIONAL STRATEGY FOR SUPPORTING SOCIAL START-UPS which will be built on the 10 local-regional strategies which will be realised in project regions._x000D_
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Besides main outputs, BEGIN expects additional project milestones being the elaboration of BUSINESS MODELS for the Management and Creation of SOCIAL START-UPS as well as LEARNING PROCESSES for the dissemination of business models.
Glitazones are associated with reduced risk of COPD exacerbations and mortality among patients with diabetes

Introduction: Moderators of systemic inflammation may reduce risk of exacerbations among patients with COPD. Glitazones, used in the treatment of diabetes, also have anti-inflammatory properties. We sought to assess whether glitazones were associated with a decreased risk of COPD exacerbations and mortality. Study design: We performed a cohort study between 10/2005-09/2006 of all US veterans who received an oral antihypoglycemic medication (sulfonureas, biguanides, or glitazones) on more than one occasion. Our outcome measures included outpatient COPD exacerbations, hospitalization for COPD, and all cause mortality. Our primary exposure was glitazone use compared to sulfonureas and/or biguanides. We used GEE to estimate the effect of glitazones and to adjust for potential confounding factors. Results: We identified 600,366 patients. Adjustment for age, sociodemographic characteristics, comorbidity, and markers of COPD severity had minimal effects on the point estimates. In comparison to either a sulfonylurea or biguanide, glitazones were associated with a significantly reduced risk of outpatient exacerbation (Adjusted relative likelihood (Adj-RL), 95%CI: 0.79 (0.72-0.86), hospitalization for COPD exacerbation (Adj-RL, 95%CI: 0.82 (0.69-0.97)) and all cause mortality (Adj-RL, 95%CI: 0.89 (0.85-0.93)). These estimates were robust to sensitivity analyses that imposed increasingly strict definitions of COPD. Conclusion: Glitazones were associated with a significant reduction in COPD exacerbations and all cause mortality. We hypothesize that this association may be mediated through the anti-inflammatory properties of glitazones. Funding: Gilead Sciences, Inc., & VA HSRD
Coca – Ein indigener Beitrag zur europäischen Wissenschaft

Zusammenfassung Die Entdeckung der Cocapflanze und Entwicklung ihres Anbaus stellt eine einzigartige Kulturleistung der indigenen Bevölkerung im heutigen Bolivien und Peru dar. Für die europäische Wissenschaft war sie Grundlage für die Isolierung des Cocains, dessen Strukturaufklärung, industrielle Produktion und die Entwicklung von Ersatzstoffen erheblich zum Fortschritt der wissenschaftlichen und industriellen Chemie beitrugen. Ohne die Entdeckung der Lokalanästhesie durch Cocain, wäre auch die moderne Medizin undenkbar, da Lokalanästhetika im klinischen Bereich die mit am häufigsten eingesetzten Medikamente sind. Auf der anderen Seite wurden die Ursprungsländer in der 1. Hälfte des 20. Jahrhunderts vom wirtschaftlichen Erfolg des Cocains zunehmend ausgeschlossen. Der seitdem weltweit verbreitete Cocainismus ist als westliche Erfindung den Ursprungsländern nicht anzulasten, so dass es eine weitere Benachteiligung ist, dass ihnen durch die vielfache Gleichsetzung von Coca und Cocain die traditionelle Vermarktung der Coca als Genussmittel erschwert wird.
Baugruppe für einen Antriebsstrang eines Kraftfahrzeugs

Baugruppe (1) für einen Antriebsstrang eines Kraftfahrzeugs, insbesondere für eine Zentralsynchronisierung, umfassend ein Gangrad (2) mit einer Laufverzahnung (3) und eine eine Reibfläche (6) aufweisende Reibeinrichtung (4), wobei das Gangrad (2) und die Reibeinrichtung (4) als separate Bauteile ausgebildet und miteinander koppelbar oder gekoppelt sind.
Probability of subsurface fatigue initiation in rolling contact

Subsurface initiated rolling contact fatigue cracks initiate in the vicinity of material defects. As these exist randomly in the material, fatigue will appear randomly under otherwise constant conditions. By combining statistical methods with a contact mechanics and fatigue analysis, probabilities of fatigue initiation are evaluated. The developed model takes as input contact geometry, contact load and the statistical properties of the material defects.

It is shown that under some well-defined presumptions the probability of rolling contact fatigue initiation in a rolling wheel can be expressed by a simple formula. Based on this, the parametric influence is assessed and it is found that the mean material defect size has a large influence. The benefit of material cleanliness testing procedures and the influence of the allowed defect size on the risk of subsurface initiated rolling contact fatigue in railway wheels are then quantified with the aid of numerical simulations.