SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Aspects Regarding some Simulation Models for Logistic Management

Abstract The main purpose of the paper is to develop a neural network application that could predict supplier problems in terms of stock management, lead time and production. Stocks of goods that manufacturers would classify as raw materials stocks are, in a special sense, goods in early stages of the production process. In a logic-based economic competitiveness, the company which holds the largest stock is underperforming! Technically, the stock is inevitable and in some cases even desirable; economically it is associate with an asset value stock, therefore, it should be minimized. Minimizing the value, the costs will also be minimized.
ORTHO-SUBSTITUTED (3-HYDROXYPHENYL)-ACETIC ACID BENZYLIDENE HYDRAZIDES

The invention relates to the novel ortho-substituted (3-hydroxyphenyl)-acetic acid benzylidene hydrazides of formula (I), wherein R<SUP>1 </SUP>to R<SUP>9</SUP> are defined as in claim 1. Said novel compounds are SGK inhibitors and can be used in the treatment of SGK-relates diseases and disorders such as diabetes, obesity, metabolic syndrome (dyslipidemia), systemic and pulmonary hypertension, cardiovascular diseases and renal diseases, and generally for any kind of fibroses and inflammatory processes.
Training network on the conversion of co2 by smart autotrophic biorefineries

The development of processes for the utilization of renewable resources is one of the main challenges of our society. The CONCO2RDE EJD will train 11 ESRs in cutting edge research projects on (i) the combination of synthetic biology approaches with metabolic and process engineering for an adaptive laboratory evolution to create an efficient route from CO2 fixation to the production of chemicals, (ii) H2/CO2/O2-based fermentation and process intensification in order to optimize commercially relevant processes together with industry, (iii) defining a road-map for the industrial implementation of autotrophic biotransformations. The double degree program allows in-depth training in two complementary disciplines, further strengthened by a transferable skills training with strong industry participation. The objectives will be attained through a consortium of one translational institute, six universities, eight industrial partners and one cluster, providing the ideal environment to foster complementary expertise in synthetic biology, metabolic engineering, biocatalysis, process engineering and analytics. CONCO2RDE focuses on the development of genetic tools for strain manipulation, the integration of H2-driven biotransformations, new reactor concepts for H2/CO2/O2-based fermentation to reach high cell densities and a better understanding of the cell physiology under autotrophic culture conditions. CONCO2RDE's research agenda will be accompanied by a dedicated training of the ESRs as well as the dissemination of results to the scientific community and the wider public. The inter- and multidisciplinary setting offered through double degrees combined with industrial training in secondments and the training agenda will not only provide the tools and means necessary for the implementation of sustainable processes, but also prepare the next generation of researchers for the implementation of sustainable autotrophic processes in the European Biotech sector.
A flexible visual quality control algorithm for perceptual video encryption based on H.264

In order to meet all kinds of video security applications, especially pay-digital-TV system, a perceptual video encryption scheme based on visual quality control strategy is proposed. The optimal syntax elements and sensitive coded elements are chosen to encrypt by using mathematical XOR operations with stream ciphers generated by Chen chaos system. In order to enhance the security, the encryption scheme of this paper synthetically uses three strategies, including Motion Vector Difference (MVD) encryption, intra prediction mode encryption and levels of low coefficients encryption. The variable length keys are used to encrypt the syntax elements to improve key utilisation. Experimental results show that the proposed perceptual encryption scheme can achieve high security at a relatively high compression ratio and bandwidth cost, as well as about 2% coding rate and 6% encoding time increased at the cost of slightly sacrificing code rate and encoding time. Especially, the degraded visual quality can be controlled gradually with a simple quality factor.
SPORT WALL AND SPORT WALL SYSTEM

An anchoring panel for a sport wall system with a front side facing an interior of the sport wall system, a back side, a flange extending from and rigidly fixed to the back side, a top side, a bottom side, and a first and second end wall is provided. Each of the first and second end walls include interlocking elements for interlocking with a first or second end of another panel in the sport wall system, the interlocking elements comprising at least a male knob extending towards the bottom side of the anchoring panel and configured to be insertable into a panel recess of the another panel in the sport wall system.
SUSPENSION CULTURE OF HUMAN EMBRYONIC STEM CELLS

This disclosure provides an improved system for culturing human embryonic stem cells. The cells are cultured in suspension so as to maximize the production capacity of the culture environment. The new culture system of this invention allows for bulk proliferation of hES cells in a more cost-effective manner, which facilitates commercial production of important products for use in human therapy.
SHORT-CIRCUIT CURRENT LIMITER FOR A CONVERTER CIRCUIT WITH A CAPACITIVE ACCUMULATOR

The invention relates to a short-circuit current limiter, comprising at least one power semiconductor switch (T1, ..., T6) with a corresponding free-wheeling diode (D1, ..., D6) as well as at least one capacitive accumulator (C), which create a short-circuit mesh in the event of a short circuit. According to the invention at least one passive semiconductor current limiter (12) made of silicon carbide is arranged in said short-circuit mesh. In this way, in the event of a short circuit the short-circuit current is limited in a very short time to the limit current (Ilimit) of the passive semiconductor current limiter (12) while placing very little load on the power semiconductor switch (T1, ..., T6).
Molecular and structural pharmacology of adiponectin receptor: towards innovative treatments of obesity-related diseases.

The human kind is witnessing an escalation of obesity-related health problems such as cardiovascular diseases and type 2 diabetes. A recent groundbreaking study revealed adiponectin receptors (ADIPOR) as key targets for treating such obesity-related diseases. Indeed, the modulation of this integral membrane protein by small molecules agonists ameliorates diabetes and prolongs lifespan of genetically obese rodent model. Despite these exciting results and the importance of ADIPOR in human physiology, there is a complete lack of knowledge of ADIPOR mechanisms of action and pharmacology. This is mainly due to the challenges associated with the characterization of membrane protein structure and function. To fill this gap of knowledge and based on my extensive experience in membrane protein biology, I propose here to characterize the the proximal signaling pathways associated with ADIPOR activation as well as the molecular and structural mechanisms of ADIPOR activation. We will develop an innovative integrated strategy combining state-of-the-art molecular and structural pharmacology approaches including 1) molecular analyses of ADIPOR network of interaction using resonance energy transfer measurement in living cells and a proteomic analysis and 2) structural analyses of ADIPOR and signaling complexes using biophysics and X-ray crystallography. Our data will have a major impact on drug discovery for treating obesity-related diseases as it will enable the application of structure-based drug design and in silico screening for the molecular control of ADIPOR activity. The proposed high-risk endeavor of obtaining structural data on these atypical membrane signaling complexes is a new direction both for my career and for the field of adiponectin biology; the exceptionally high gain from these studies fully justifies the risks; the feasibility of this project is supported by my recent success in membrane protein pharmacology, biochemistry, biophysics and crystallography.
María LÓPEZ DÍAZ (ed.), «Monarquías ibéricas, poderes y territorios. Instituciones, nobleza y dinámica política (siglo XVIII)», Madrid, Sílex, 2021, 422 págs.

Sin resumen.
Lifecall wearable ekg heart health monitoring, analysing and warning system

Cardiac arrest is the leading cause of death that annually more than 17 million die in the World, 3 million in Europe.

Worldwide 320 billion$ is spent for medication and diagnostics. EKG is a critical element of heart health. The longer we record EKG, deeper the diagnosis we can achieve.

LifeCall is a mobile, wearable EKG device which captures real time EKG and stores it remotely to share with related parties.

It consists of a shirt with newly developed innovative conductive textile electrodes and a device which can read real time EKG and sends it to our mobile application. It has no gel based electrodes since we use a special textile that can conduct low voltage electricity. This use of the nanotechnology based textile is unique.

Our system can record EKG almost for 3 weeks without interruption, with low energy components, optimized wireless transactions. This can open up new era to health care industry. Critical life threatening heart events can be captured before actual damage is done, with just a basic shirt and its supporting ecosystem which is not possible with conventional hospital holter EKG.

There will be 2 separate products that will be commercialized individually:

1) A shirt and accompanying device that captures real time EKG data. The device will pass EKG data to mobile phone for recording which will later be pushed to our servers in a secure and private way.

2) A platform for analysing, routing and sharing of these EKG outcomes with related parties through mobile and desktop applications.

Our target end-users can be considering anyone that may have cardiovascular risk who is between 40 to 65 years old with arrhythmia complications, but pinpointing maximum impact complication is also a target of our feasibility study.

In phase 1, we will conduct a feasibility study on market, pinpoint maximum impact hearth complication, risks, strategy and financial requirements. In phase 2, we will deliver the product based on phase 1 outcome.
Influence of periodicity on the reflection properties of finite periodic media

The dispersion relation of periodic systems, the well-known bands structure, gives the information about the propagating modes inside the media. These bands reveal both propagating and non-propagating ranges of frequencies. It is well known that the transmission properties, with relation to the propagating modes, can be characterized by both the bands structure and the equifrequency contours. Oppositely, in finite systems, one should consider the reflection properties on the interface defined by the host and the periodic media in order to know the spatial distribution of the reflected field. In this work, we analyze the reflected acoustic field by a periodic system. An experimental set up is proposed in this work to analyze the reflection properties of a periodic media. From the exploitation of the properties of both the interface and the inner periodicity of the crystal, fundamental and applied questions can be discussed using this media.
Eu space awareness

EUSPACE-AWE uses the excitement of space to attract young people to science and technology and stimulate European and global citizenship. Our main goal is to increase the number of young people that choose space-related careers.

We shall target diverse groups that influence career decisions, showing teenagers the opportunities offered by space science and engineering and inspiring primary-school children when their curiosity is high, their value systems are being formed and seeds of future aspirations are sown. 

Activities will 1. Acquaint young people with topical cutting-edge research and “role-model” engineers, 2. Demonstrate to teachers the power of space as a motivational tool and the opportunities of space careers, 3. Provide a repository of innovative peer-reviewed educational resources, including toolkits highlighting seductive aspects of Galileo and Copernicus and 4. Set up a “space career hub” and contest designed to appeal to teenagers. Attention will be paid to stimulating interest amongst girls and ethnic minorities and reaching children in underprivileged communities, where most talent is wasted. Targeting policy makers via high-impact events will help ensure sustainability and demonstrate the social value of the space programme. 

We maximise cost effectiveness by 1 “Piggy backing” on existing ESERO and other teacher training courses and 2. Exploiting and expanding infrastructures of proven FP7-Space projects, EU Universe Awareness for young children and Odysseus for teenagers. 

EUSPACE-AWE will complement existing space-education programs and coordinate closely with ESA. We shall reach European teachers, schools and national curricula through host organisations of ESEROs and the extensive networks of European Schoolnet, Scientix and UNAWE. Designated nodes will provide curriculum and resource localisation and test beds for professional evaluation.  A partnership with the IAU Office of Astronomy for Development in Cape Town ensures global reach.
Magnetic identification

The project consortium consisting of BOGEN (project coordinator, SME), INESC (research), and INSPECTRON (SME) will bring the novel identification solution for track & trace, anti-counterfeiting and product verification to market. INSPECTRON has recently developed a magnetic ink barcode reader and has implemented this in a mailer project. BOGEN has developed with INESC a new technology to read magnetic ink with TMR sensing technology. Combining these approaches results in a disruption for the identification and authentication/anti-counterfeiting markets with Mag-ID, the magnetic readable barcode based on ink. The objective of this action is to introduce Mag-ID as a cost-efficient alternative for high volume tracking & tracing, brand protection and inspection and to replace passive RFID as a cheap solution for high volume applications. Since magnetic barcodes are dirt resistant, the technology will replace some barcodes with a more reliable read. The technology allows for distance reading, which means that the information can be read through coatings, e.g. parts before and after a paint booth can be identified automatically with the same technology. This can be used for tracking and tracing of components in a subassembly e.g. in identification documents to ensure that personal data and pictures are matched in the process and after assembly. Together with a verification as a service platform, SMEs can provide authentication and validation services world-wide. Magnetic barcodes can replace many RFID solutions as they are environment-friendly without separate electronic device disposal. Within Mag-ID, the SME partners will demonstrate the results manifold: BOGEN Mag-ID one-shot reader in a volume application, INSPECTRON with evaluation modules for the Mag-ID brand protection, tracking and inspection solutions. INSPECTRON will move into a service-based business model, while BOGEN will create a separate business for a project-based model.
Environmental research Management in Peru

espanolEl articulo revisa la situacion de la investigacion ambiental en el Peru a la luz del aumento nacional de presupuesto destinado a la investigacion. Se resaltan las peculiaridades y metodologia cientifica que utilizan las ciencias ambientales y se discuten sus dificultades. Se analiza la estrategia para mejorar la gestion de la investigacion ambiental, sosteniendo la necesidad de poner mayor enfasis en la investigacion ambiental aplicada. Finalmente, se describen los roles institucionales y avances en la materia y se plantean propuestas para la mejora de la gestion. EnglishThe article looks over the situation and management of the environmental research in Peru, with regard to the national politic to increase the budget for research. Moreover, the characteristics and methodology of the environmental sciences research are addressed and its difficulties are discussed. The national efforts and strategy to improve the management of environmental research are analyzed, establishing the need to emphasize efforts in the promotion of applied environmental research. Finally, the institutional roles and progress in the matter are described, and a proposal to improve the environmental research management is presented.
A study of quality teaching in the Secondary Schools of Karachi

The present study aimed at finding out the factors affecting the quality teaching at the secondary level. Moreover, this study examined the existing academic and administrative state of schools, how they are supervised, and how they can be made effective to provide quality teaching. The population of the study comprised of the public secondary schools of Karachi. Survey method was used to conduct research. The sample consisted of 400 teachers who were randomly selected from the four towns of Karachi. Twenty two schools were selected through systematic random sampling. The questionnaire was used for collecting data which consisted of 40 items with five-point Likert Scale. The collected data were tabulated, calculated, analyzed, and interpreted in the light of objectives of the study, and the research hypotheses. Moreover, inferential statistics was used for testing of hypotheses i.e. χ2-test.
AN UNDERGROUND ROADWAY SUPPORT

An underground roadway support comprises interconnected side-by-side arch sections (20, 21, 22) each constituted by a plurality of interconnected panels (23, 24, 25). Each panel comprises a plurality of arch sections butted and coupled together, the panel being of rectangular configuration and having on two opposed sides formations adapted movably or adjustably to engage complementary formations on corresponding panels of adjacent arch sections to provide mechanically flexible connections therebetween. The formation on one side of a panel is a channel (31) open outwards of the panel, while the formation on the other side of the same channel is a box section (32) adapted to engage within a channel formation of an adjacent panel to form, in effect, a knuckle joint thus to permit joined panels, and consequently joined arch sections, to accommodate earth strata irregularities or variations.
The recycling of waste heat through the application of nanofluidic channels: advances in the conversion of thermal to electrical energy

Increasing energy consumption, the depletion of natural resources, climate change and decreasing air quality are among the biggest economic and social challenges that we face today. At the same time, waste heat energy discharged into the atmosphere is one of the largest sources of clean, fuel-free and inexpensive energies available, with 70 % of all energy generated on a daily basis being lost as waste heat. Although technologies for converting waste heat into electrical energy have been around for a long time, such as thermoelectric and thermo-electrochemical cells, there is still no environmentally sustainable and efficient technology platform available for the viable harvesting of low-grade waste heat. There is therefore a clear need to develop an energy harvesting and conversion technology which has the potential to exceed the efficiency of current state-of-the-art devices whilst also utilising Earth-abundant materials. The central aim of TRANSLATE is therefore to develop a new proof-of-concept nanofluidic platform technology based on the flux of ions in nanochannels; leading to a breakthrough in versatile and sustainable energy harvesting and storage.

Three breakthrough science and technology targets have been identified: 1) optimisation of ion movement and ion separation in nanochannels made from Earth-abundant materials, 2) the development of a sustainable and efficient heat-to-electrical energy platform and 3) the creation of a novel continuous operation energy harvesting power source with a high power/energy density and conversion efficiency.

Expertise in materials science, nanofluidics, nanofabrication, thermoelectricity and electrochemistry is integrated on a pan-European level to achieve the overall aim of the project. The knowledge developed in TRANSLATE has the potential to reduce energy consumption and associated greenhouse gas emissions on a local and global scale, thus improving citizens' quality of life and benefiting society.
Construction components for use in civil engineering structures.

A construction component has a plurality of male and female lock assemblies for engagement with female and male lock assemblies of a similar construction component for locking the two components together. The male lock assemblies are arranged in vertical tandem pairs, as are the female lock assemblies. Each of the male lock assemblies includes a rigid pin which is reciprocable with respect to the component between an advanced position and a retracted position. Each female lock assembly defines a socket opening and includes a transversely reciprocable lock for locking a pin in the socket opening. The male lock assembly includes a similar transversely reciprocable lock adapted to lock the pin in at least one of, and preferably both of, its two positions. The locks of each tandem pair of assemblies are connected for joint movement and are adapted so that, when lowered, the lower lock engages its respective pin before the upper lock engages its pin. The structural component is in the form of a rectangular parallelepiped with gross dimensions corresponding to those of a standard freight container. All parts of the lock assemblies are retained against separation and are designed to lie generally within such gross dimensions, so as not to interfere with handling of the construction component in the manner of a standard freight container.
GENERATING TARGETED SEQUENCE DIVERSITY IN FUSION PROTEINS

Methods of generating fusion protein variants are provided that comprise introducing sequence diversity at the junction region or regions in the fusion and allows for the generation of variants having a desired activity. Examples include immunoglobulins comprising a domain or polypeptide inserted into, or replacing, a CDR. Also provided are polynucleotides encoding a fusion protein and comprising two or more RSSs, and compositions and host cells comprising same, as well as fusion proteins variants produced by the described methods.