SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Microfluidique à l'échelle micrometrique et sub-micrometrique : NanoPTV, formation des gouttes, et modèle sub-micrometrique

In this work, we have addressed three projects with the application of Microfluidics: With the technology of Total Internal Reflection Velocimetry, we realised the nano-PTV of fluid flow within 800 nm close to solid surface. We achieved unprecedented accuracy of measurement compared with the state of art, by determining precisely the wall position, and by Langevin simulation, which takes into account of the sources of biases, such as Brownian motion, shear stress, electrostatic repulsion between particles and the wall, effect of out of focus, etc. We achieved ±5 nm and ± 10 nm accuracy on the slip length determination for sucrose solution and for water. The no-slip condition on hydrophilic surface is confirmed, and a positive slip length on hydrophobic surface is clearly illustrated. This result demonstrated that the nano-PTV by TIRF is a quantitative methodology for the study of fluid flow near solid surface. We collaborated with A. Leshansky to study quantitatively the mechanism of step emulsification. The dispersed fluid and continuous fluid are co-flowing in a confined Hele-Shaw channel, before going into an unconfined pool. Drops are formed at the intersection between shallow channel and the pool. Two phases - step emulsification and large drops - are distinguished based on a well defined capillary number. We found good agreement between experiments and theory, on the step emulsification droplet size, dispersed fluid pinching dynamics, and on the shape of free interface between dispersed fluid and continuous fluid prior to pinching. We collaborated with a group of petroleum companies (AEC), to develop a technology which has potential application to the Enhanced Oil Recovery. Nano particles synthesized by the AEC is supposed to perform phase transition or deliver signals once in touch with oil. The principal idea consists in sending these nano particles into the porous media underground along with the injection fluids, and recollect them on the production well side. According to the information they deliver, the distribution of oil may be mapped. We constructed a micro model based on microfluidic technology, which mimics the complex structure of porous media of rocks. The AEC synthesized nano particles are injected into the micro model, their motion and retention can be observed in real time. This work provides important information on the particle motion in porous media, which cannot be realised in conventional core experiments.
Extended Linguistic Variable and Its Effective Set

The paper aims to expand the concept of linguistic variable. The study analyzes the common conclusion forms in the evaluation project. The evaluation often makes the final conclusion by analyzing the fuzzy number and its membership function. However, the information of modified word or phrase (“largely”, “preliminary” and “unclear”) has got lost in analysis. The research believe these modified words imply the inherent re-judgments on the mainly conclusions. And the study develops the extended linguistic variable by integrating the modified and traditional linguistic variable. Then the study defines the effective set of extended linguistic variable. The effective set suggest the valuable scale of the extended linguistic variable.
Identification and characterization of novel essential regulators of acute myeloid leukemia

Acute myeloid leukemia is a hematopoietic malignancy characterized by the abnormal proliferation of immature myeloid cells. The implementation of high-throughput sequencing revealed that somatic mutations in various epigenetic regulators represent a frequent pathogenic phenomenon in leukemogenesis. This raised optimism for the development of new therapies in leukemia due to the reversible nature of epigenetic marks and amenability of chromatin-modifying enzymes to pharmacological inhibition. However, realization of this potential requires further research into epigenetic mechanisms governing the maintenance of leukemic cells. The overall goal of the proposed work is to characterize novel important epigenetic regulators in leukemic cells and to assess their potential as drug targets. Firstly, I plan to identify and study epigenetic regulators essential for leukemic cells deficient in TET2, an enzyme that hydroxylates methylated cytosines in DNA. This will be achieved by performing state-of-the-art shRNA screens in mouse Tet2-null leukemia models and by exploring the functions of the uncovered candidates using a range of cell biology, biochemistry, and functional genomics approaches. The second aim is to investigate the molecular functions of SETD5, a newly-uncovered epigenetic regulator of leukemic cells. This will be achieved by identifying its target genes and interacting partners in leukemic cells and by exploring the effects of its depletion on normal and cancer cells. The accomplishment of both research aims will provide new insights into epigenetic regulation of leukemic cells and highlight novel drug targets for future therapy development. The project will be supervised by Prof Kristian Helin, a world-leading expert in the field of epigenetics and cancer. Through this work, I aim to broaden my scientific expertise by acquiring numerous technical and transferable skills and to establish myself as an independent researcher in the field of cancer epigenetics.
Network for research and technology transfer for the improved use of economically underestimated cereals and pseudocereals

The overall objective of the project is to strengthen cross-border cooperation among universities, research centers and companies, through the establishment of a network of partners with multi-disciplinary skills (genetics, agronomy, chemistry, nutrition, and food production). The “minor” cereals (MC) and pseudo-cereals (PC) such as buckwheat, millet and oats, cultivated in the Program area until mid-twentieth century, are nowadays neglected in favor of more profitable wheat and corn. This leads to negative consequences, such as over-exploitation of land in monoculture, and the loss of nutrients considered subordinate to the maximization of the technological performance of the cereals. _x000D_
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On the contrary, MC and PC have several positive aspects: their cultivation increases biodiversity and environmental sustainability (as they require limited agronomic inputs) of the food chain, and their wealth in minerals, amino acids and vitamins enriches our diet. Hence their importance for the gluten-free food industry and the traditional one, where wheat is used. Given this background, the project aims to establish a network that can share skills and transfer knowledge_x000D_
in order to support the spread of MC and PC, by means of genetic selection and improvement activities, and to promote their use in food industry and strengthening of nutraceutical components in bread, pasta and biscuits.
Regulation of plant receptor kinase-mediated immunity by endogenous peptides and their receptors

Plant receptor kinases are major pattern recognition receptors (PRRs) that function as part of dynamic multimeric complexes to perceive pathogen-associated molecular patterns or host-derived damage-associated molecular patterns at the plasma membrane (PM). Our long-term objective is to decipher the molecular basis of plant innate immunity and to understand how plant receptor kinases work. 
Our recent findings point to an important role of endogenous peptides in the regulation of plant innate immune signaling. The main aim of this proposal is to understand how these endogenous peptides and their corresponding receptors regulate plant innate immune signaling. The central hypotheses of this research are that: (i) a subset of plant endogenous peptides are perceived by receptor kinases to fine-tune dynamically plant innate immune signaling, and thus act as ‘phytocytokines’; (ii) these phytocytokines and their receptors regulate the formation of active immune-signaling nanoclusters at the PM; and (iii) phytocytokine receptors participate in the sensory continuum represented by the plant PM and the cell wall to respond dynamically to environmental challenges. 
We will pursue the following specific objectives: 
(1) decipher the regulation, function, and perception of RALF peptides by malectin-like receptor kinases during immunity; 
(2) elucidate the formation, composition, and function of PM immune receptor nanoclusters; 
(3) reveal the function of the receptor kinase MIK2 and its ligand(s) in immunity. 
Through a balanced combination of straight-forward and high risk/high gain biochemical, biophysical, bioimaging, and genetics approaches, this project will provide groundbreaking insights into the molecular mechanisms underlying the establishment and regulation of plant innate immune signaling, but also into the general mechanisms that control plant receptor kinase functions and by which the myriad endogenous peptides encoded by plant genomes control environmental sensing.
The evolutionary significance of synonymous variations: can codon usage preferences drive the propagation of antibiotic resistance?

The intensive use of antibiotics provided an unprecedented improvement in infectious disease treatments but at the expense of creating ideal conditions for the selection of widespread resistance. Propagation of antibiotic resistances is favoured by horizontal gene transfer and by bacterial life in multispecies community. However, compositions of resistome and bacterial communities are often correlated, suggesting that propagation of resistances does not occur at random. This project will test the hypothesis that mismatch in codon preferences between the transferred genes and the receiving genome is a fundamental factor shaping resistome structure and evolution. Such central role of codon preferences may have been hitherto overlooked. The project combines mutant collection characterization, experimental evolution approaches –one in a multispecies context and one in a variable environment context-, full genome sequencing of evolved populations, phylogenomics and mathematical modelling integrating the experimental results of the other approaches, and generating a predictive tool about the evolutionary outcome of various real-life situations.
PARKING GARAGE

Parking garage having at least two parking areas inside said parking garage, each parking area comprising a plurality of parking spaces adjacent to a wall, a wall segment of said wall extending along said plurality of parking spaces, said wall segment having a color pattern comprising at least two contrasting colors, whereby the color patterns of wall segments of different parking areas differ in color and in the pattern of the color patterns.
Working capital grant for INFINITY Mobile Cosmetic Studio Kamila Jedynak

The project concerns support to the company to provide liquidity and to support its day-to-day operations in view of the financial difficulties that have occurred in the company as a result of the COVID-19 outbreak. Financial aid under scheme SA.57015
USING BORON-CONTAINING COMPOUNDS, GASSES AND FLUIDS DURING AMMONOTHERMAL GROWTH OF GROUP-III NITRIDE CRYSTALS

Boron-containing compounds, gasses and fluids are used during ammonothermal growth of group-Ill nitride crystals. Boron-containing compounds are used as impurity getters during the ammonothermal growth of group-Ill nitride crystals. In addition, a boron-containing gas and/or supercritical fluid is used for enhanced solubility of group- Ill nitride into said fluid.
E-Rescue system: the next level in post-accident-safety. saving time and lives during the golden hour

Road safety is a major societal issue. Each year around 30,000 people die on the roads of the European Union, i.e. the equivalent of a medium town. Additionally, for every death on Europe's roads there are an estimated 4 permanently disabling injuries such as damage to the brain or spinal cord, 8 serious injuries and 50 minor injuries. Many of the casualties or injured could have been avoided by saving time during the immobilisation and extrication of the victims from the vehicle. In this field of expertise, emergency services speak of the Golden Hour, the estimated maximum time for getting road-accident victims to hospital. After this time, the most seriously injured have very little chance of survival. Additionally, there are experts who estimate that 15% of spinal cord and similar injuries in road accidents are provoked by incorrect immobilisation and extrication of victims. e-Rescue system, like e-Call, has been developed to solve this problem. It is a patented system to be incorporated in the seats of any vehicle which, in case of an accident, prevents unnecessary movement of the patient and it saves precious time for the immobilisation and extrication of the victims. Additionally, the system can be implemented in a cost-effective manner and become a competitive advantage for the EU automotive industry.
Divide and Conquer: Functional Segregation of Synaptic Inputs by Astrocytic Microdomains Could Alleviate Paroxysmal Activity Following Brain Trauma

Traumatic brain injury often leads to epileptic seizures. Among other factors, homeostatic synaptic plasticity (HSP) mediates posttraumatic epileptogenesis through unbalanced synaptic scaling, partially compensating for the trauma-incurred loss of neural excitability. HSP is mediated in part by tumor necrosis factor alpha (TNFα), which is released locally from reactive astrocytes early after trauma in response to chronic neuronal inactivity. During this early period, TNFα is likely to be constrained to its glial sources; however, the contribution of glia-mediated spatially localized HSP to post-traumatic epileptogenesis remains poorly understood. We used computational model to investigate the reorganization of collective neural activity early after trauma. Trauma and synaptic scaling transformed asynchronous spiking into paroxysmal discharges. The rate of paroxysms could be reduced by functional segregation of synaptic input into astrocytic microdomains. Thus, we propose that trauma-triggered reactive gliosis could exert both beneficial and deleterious effects on neural activity.
Bct and Theory use in Interventions Targeting Initiation and Maintenance of Weight Loss – Systematic Review

Background: Behavioural interventions produce weight loss, but weight loss maintenance is elusive. The correspondence between behaviour change techniques (BCTs) used to initiate and maintain weight loss and the effect of theory use on weight loss maintenance is currently unknown. Methods: Systematic review of interventions inducing weight loss (?5% body weight) in obese adults followed by randomisation to different maintenance treatments reporting weight outcomes ?12 months. BCTs were compared for weight loss vs. maintenance phases, and associations between theory and weight maintenance effects were examined. Findings: 45 RCTs met inclusion criteria, including 9451 participants (BMI=35.2). Most studies employed the same BCTs targeting initiation and maintenance. Instruction provision, self-monitoring and problem solving were the most frequently employed BCTs. Theory based interventions were more effective compared to non-theory based ones [-2.3kg 95%CI -3.2 to -1.5 vs. -0.1 95%CI -1.2 to 0.9, P<.001). Discussion: There is a lack of differentiation between BCTs used for initiation and maintenance of weight loss. Theory based maintenance interventions were found to be more effective.
The discursive representation of Iran’s supreme leader in online media

This study examines the interplay of politics, religion and discourse in the representation of the Iranian Supreme Leader, Ali Khamenei, in government-controlled news websites in Iran. It is grounded in critical discourse analysis (CDA), and Van Leeuwen’s social actor network model (2008) is used as the theoretical framework to analyse the linguistic representation of the Iranian leader. In the samples analysed, Khamenei is discursively depicted by features associated with the Prophet Muhammad and the 12 infallible Imams of the Shia tradition. Such representations elevate the authority of Khamenei in texts, and naturalise the ideology of Velayat-e Faqih, which authorises a Faqih (Jurist) to assume political leadership in Iran. In this way, the texts are used to maintain and reinforce the dominance of people in positions of power.
Consumers in Action

The project ConACT aims at the creation, establishment and dissemination of a wide network of Local Centres for Consumer Protection in order to create a Mediterranean cluster for intervening in the application of the European consumer policy in a more drastic method. The participating regions are characterised by important tourist activities and visits of tourists that are facing small or largest problems during their staying in the regions. The project aims at providing a consumer protection policy focused on tourism and services related activities, improving the dialogue with EU citizens and promoting consultation as a common framework for successful governance in consumer protection policy. The direct involvement of consumers and their effective representation is essential in order to act as counter-balance to other strong interests and to participating the policy making process. The main objectives of the project can be summarised as follows: • Beginning of dialogue among the participating countries in regional and national level as a part of the bottom up approach for involving citizens on the policy making procedure for consumers’ matters. • Enhanced cooperation through the creation of additional specific information networks concerning consumers policy protection matters by the establishment of one Local Centre for Consumer Protection (ConACT Center) in each participating region, operating under the supervision of the relevant public authorities. • Specification of one suitable development model for local application in the field of consumer protection policy in the south-eastern Mediterranean. • Elaboration of instruments for promoting the involvement of local stakeholders, consumers and citizens in order to enhance the EU citizenship with innovative ICT tools such as the Consumer Information System • A single market in which consumers have the necessary information and skills to shop cross-border and an appropriate regulatory framework which will enable them to do so with confidence.
Traveling waves: defining the mechanisms allowing attention to occur in space and in time

Brain oscillations have always fascinated both scientists as well as the general public, but their functional role remains ill defined. My research contributed to addressing this issue, and demonstrated that oscillations modulate attentional performance periodically in time. Oscillations create periodic windows of excitability, with more or less favorable periods recurring at particular phases of the oscillations. However, attention emerges from systems not only operating in time, but also in space. Previous research has emphasized the temporal aspect of brain oscillations’ behavior. Contemporary investigators rarely consider both temporal and spatial dimensions in their search for the mechanisms linking oscillations and attention. This is the challenge I propose to take on. I will address this essential question: How does the spatio-temporal organization of brain oscillations impact attention? I hypothesize that oscillations propagate over the cortical surface, so-called oscillatory Traveling Waves, allowing attentional facilitation to emerge both in space and time. I propose to test this original hypothesis using a model-based multimodal functional neuroimaging approach including non-invasive and invasive recordings in humans. Interventional approaches will additionally be used to evaluate the degree of causality in the relation between traveling waves and attention. This project could lead to major progress in cognitive psychology and neuroscience by bridging the gap between spatial and temporal dynamics underlying multi-sensory experience. An important methodological development is also expected. The model-based multimodal functional neuroimaging approach that I will develop and evaluate on a large set of data will provide a new methodological guide for the study of brain activity.
Graphene molecule interfaces for spintronics

The future of our society is intimately bounded to the development of smaller, faster and cheaper technologies, which can promote the ability to read, store and manipulate data. Spintronics addresses the issue by encoding information into the spin degree of freedom of electrons, in alternative or in addition to the charge. Currently, the progress of spintronics depends on the engineering of new advanced materials, which can promote the injection and transmission of the spin of electrons into the condensed matter. ARTEMIS will tackle the problem through the fabrication and study of graphene/molecule hybrid interfaces, taking advantage of both the exceptional physical properties of graphene and the additional degrees of freedom provided by molecular complexes. ARTEMIS focuses on the design of graphene/molecule interfaces in which a selection of molecules deposited on the graphene film will allow the spin scattering mechanisms of the material to be probed and manipulated as a consequence of charge transfer and magnetic coupling effects. The interfaces will be incorporated into spin valve devices realized with state-of-the-art nanofabrication techniques, in order to characterize their properties as a function of external parameters, such as electric field, magnetic field, temperature and optical excitation. The data analysis will allow meaningful spin transport quantities, such as the spin relaxation time, spin relaxation length, spin-orbit-coupling strength and spin-to-voltage conversion ratio, to be extrapolated in order to determine the actual device performance and compare it to the behaviour of pristine graphene films. ARTEMIS will shine light on the spin transport mechanisms in graphene and test the benefits of adopting graphene/molecule interfaces as building blocks of competitive spin-based technologies. Finally, ARTEMIS will promote the career of a young female researcher with a hands-on training on a promising interdisciplinary field of physics.
A garment

The present invention relates to a garment (1), and more particularly an underwear, sportswear or swimwear garment (1) for a female. The underwear, sportswear or swimwear garment comprises an open-sided structural frame (10) and a fabric covering (20) for the structural frame. The structural frame (10) includes an anterior contoured loop (15) and a posterior stem (12), relative to a wearer of the garment in normal use, wherein the anterior contoured loop (15) is adapted for surrounding the mons-pubis region, genitals and anus of a female wearer and has a perimeter that is contoured to conform to and engage with the anatomy of the female wearer. A portion of the perimeter of the anterior contoured loop (15) is adapted for tensioned engagement with the inner thigh muscles of a female wearer when worn, in a standing position or whilst walking. The posterior stem (12) is shaped so as to be engageable by the gluteus maximus muscles of the female wearer when worn. The anterior contoured loop (15) and the posterior stem (12) are formed in a sprung-biased arrangement relative to one another such that when the underwear, sportswear or swimwear garment (1) is worn on the female body, a tensile force is transferrable from the posterior stem to the anterior frame portion.