SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
A model-driven approach for designing multi-platform user interface dialogues

Human-computer interaction becomes sophisticated, multimodal and multi device and needs to be well-designed with the aim of facilitating application correction (i.e. to correcting errors/bugs in the application) or extension (i.e. adding new functionalities or modifying existing tasks). This thesis is focused on building a methodology of designing and specifying User Interface (UI) behaviour. The Unified Modelling Language (UML) is used to describe in detail the conceptual model and to define all its objects. The methodology flux diagram is provided with the specification of the consistency and the completeness properties of the transformation model. To support the methodology, we implement a graphic Dialog Editor in which Models are organized in three levels (abstract, concrete and final) according to Cameleon Reference Framework (CFR) and, whose process respects the Model Driven Engineering (MDE) approach. Furthermore, the use of Dialog Editor is illustrated through a simple example (connection to an interactive system with a login and a password) and another more complex example (CTI Application, relative to CTI Company, intended to cover the activities of a company which is specialized in the international transfer of money and import express worldwide services). These two examples of use have revealed strong points of Dialog Editor, as well as certain gaps. Qualitative approach is used to evaluate Dialog Editor. The assessment plan is structured in three phases. In the first instance, in the form of an interview we presented an open questionnaire to the potential users, in order to have feedback of a more or less general nature. Then, we organized a satisfaction survey by making use of the IBM Computer Usability Satisfaction Questionnaires (CSUQ). Finally, to conclude this assessment, we have applied the respondents' comments to the ISO / CEI 9126 norm criteria to have a clearer vision of the useful and usable characteristics of Dialog Editor.
Metabolic mechanical materials: adaptation, learning & interactivity

The central objective of M3ALI is to introduce concepts for adaptation, simplistic learning by training (physical exercise, not teaching), and interactivity in mechanically stimulated polymer materials by developing metabolic modules for mechanical memories (that can also be forgotten), for down-stream chemical processes and for active communication.  The key experimental methodology is based on two classes of molecularly engineered mechanoprobes (MPs) that are capable of defined downstream reactivity up to the level of chemical reaction networks (CRNs). We build on our recent concept of DNA-based mechanofluorescent folding motifs in hydrogels, and extend it to cyclic disulfide MPs, and embed them into hydrogels and elastomers of controlled topology. DNA-based MPs will engage in DNA-based downstream reactions, while disulfide MPs will engage in complementary radical chemistry.  The key concept is to code mechanical deformation into chemical signals that can be processed ultimately in CRNs to enable a behavioral evolution of the materials systems by installing memories, as well as by signal amplification, processing, translation and transport, and where the processed chemical information is fed back into the material to develop a full mechano-chemo-mechano signal processing language.  We will break new ground in proof-of-concept applications in mechanical training and forgetting (physical exercise similar to muscle training), adaptive and interactive soft robotics, adaptive mechanical metamaterials, as well as interactive mechanical synchronization and interactive cell/material systems. Our approach to metabolic mechanical materials that use systems chemistry concepts to empower mechanical materials with the capacity to adapt, learn and interact profoundly contrast present research on responsive materials. In long term such concepts will provide the basis for more life-like materials systems capable of true adaptivity, interactivity and co-evolution in open systems.
Treating post-traumatic tremor with deep brain stimulation: Report of five cases

Post-traumatic tremor is one of the most common movement disorders resulting from severe head trauma. However, literature regarding successful deep brain stimulation (DBS) treatment is scarce, resulting in ambiguity regarding the optimal lead location. Most cases support the ventral intermediate nucleus, but there is evidence to defend DBS of the zona incerta, ventral oralis anterior/posterior, and/or a combination of these targets. We report five patients with disabling post-traumatic tremor treated with DBS of the ventral intermediate nucleus and of the globus pallidus internus.Patients were referred to the Vanderbilt Movement Disorders Division, and surgical intervention was determined by a DBS Multidisciplinary Committee. Standard DBS procedure was followed.Patients 1-4 sustained severe diffuse axonal injuries. Patients 1-3 underwent unilateral ventral intermediate nucleus DBS for contralateral tremor, while Patient 4 underwent bilateral ventral intermediate nucleus DBS. Patients 1-3 experienced good tremor reduction, while Patient 4 experienced moderate tremor reduction with some dystonic posturing of the hands. Patient 5 had dystonic posturing of the right upper extremity with tremor of the left upper extremity. He was treated with bilateral DBS of the globus pallidus internus and showed good tremor reduction at follow-up.Unilateral or bilateral DBS of the ventral intermediate nucleus and bilateral DBS of the globus pallidus internus may be effective and safe treatment modalities for intractable post-traumatic tremor. Further studies are needed to clarify the optimal target for surgical treatment of post-traumatic tremor.
SPHERICALLY GUIDED SEATING SYSTEM

A base for fixing the safety seating system in a passenger car has an external guiding member that more than equatorially encompasses an internal guiding member for a direct spherical guiding of a removable seated newly born infant. The infant is seated with respect to the geometrical pivoting center and an overall mass axis of the rotating portions such that neck bending and head whip lashing are minimized during a vehicle crash. The encompassing spherical and direct guiding provides for a free impact aligned reorientation of the seated infant unimpeded by adjacent elements of the car that are eventually forced into contact during crash. The direct spherical guiding provides also for a lightweight construction of the rotating portions with low momentum of inertia and consequently high responsiveness of the safety seating system.
CEMENT-BASED MULTILAYER ASSEMBLY THAT CAN BE USED AS A BIOLOGICAL SUPPORT FOR BUILDING FACADES OR OTHER STRUCTURES

The invention relates to a cement-based multilayer assembly that can be used as a biological support for building facades or other structures, said assembly comprising: an optionally-newly-installed structural concrete layer (1), an anchoring layer (2), a biological layer (3) made from a cement-based material, and a waterproofing cladding layer (4) including cavities (5) in which the biological layer (3) is in direct contact with the environment. The biological layer (3) is made from traditionally produced concrete or mortar including a retarder- or acid-type chemical additive having a pH of between 5.5 and 8 or from a magnesium-phosphate cement (MPC) containing a phosphate source and a magnesium source. The biological layer (3) includes aggregates of the siliceous or expanded clay type, the maximum size thereof being no bigger than one quarter of the thickness of the layer.
Ultra-Lightweight concrete for 3d printing technologies

The construction industry does not follow the same enlightened path as other fields of science and has thus suffered a technology bypass, relying on centuries-old processes and procedures to manage complex modern projects. In conventional concrete construction projects, more than 60% of the total cost is spent on the formwork. One of the technologies which can revolutionize our perception and approach to construction, is 3D printing of concrete. 3D printing, also referred to as Additive Manufacturing (AM), is a technology which builds solid parts via a layer-by-layer process. Since in 3D printing, no formwork is required, and a short project time is required due to continuous work done by the printer, a dramatic reduction in the project cost and improvement of workers’ safety can be achieved. Up to date, much research has been conducted in the field of printing technique, while design of proper insulation of printed walls has gathered little attention. Although, this issue is highly important due to gradually tightening EU regulations. Therefore, proposed project is aiming to fill the gap in knowledge and introduce for the first-time insulating ultra-lightweight concrete (ULWC) material for AM. By proposed interdisciplinary methodology, based on the experimental and numerical methods, in micro- and macro-scales technology, a multi-scale tool enabling to produce advanced 3D printed wall systems. Multi-scale tool will allow to develop 3D models of ULWCs with optimized mechanical and insulating properties. Hence, limited amount of required field and labor works will be necessary, thus further decrement of the final concrete cost and waste production will be achieved. Through the interdisciplinary approach and establishing industrial cooperation, this project will contribute towards development and production of energy saving constructions in accordance with EU Energy Efficiency Strategy.
From software verification to ‘everyware’ verification

Ubiquitous computing is a vision of computing in which the computer disappears from view and becomes embedded in our environment, in the equipment we use, in our clothes, and even in our body. Everyday objects--called `everyware' by Adam Greenfield--are now endowed with sensing, controlled by software, and often wirelessly connected and Internet-enabled. Our increasing dependence on ubiquitous computing creates an urgent need for modelling and verification technologies to support the design process, and hence improve the reliability and reduce production costs. At the same time, the challenges posed by ubiquitous computing are unique, deriving from the need to consider coordination of communities of `everyware' and control physical processes such as drug delivery.

Model-based design and verification techniques have pro-ved useful in supporting the design process by detecting and correcting flaws in a number of ubiquitous computing applications, but are limited by poor scalability, efficiency and range of scenarios that can be handled. In this paper we describe the objectives and initial progress of the research aimed at extending the capabilities of quantitative, probabilistic verification to challenging ubiquitous computing scenarios. The focus is on a advancing quantitative verification in new and previously unexplored directions, including game-based techniques, incorporation of continuous dynamics in addition to stochasticity, and online approaches. The research involves investigating the fundamentals of quantitative verification, development of algorithms and prototype implementations, and experimenting with case studies.
ORAL PHARMACEUTICAL PREPARATION FOR COLON-SPECIFIC DELIVERY

An oral pharmaceutical preparation excellent in the ability to deliver a drug to the large intestine, more specifically, an oral pharmaceutical prepa ration for delivering a drug to the large intestine which comprises a core c ontaining a pharmaceutically acceptable filler as the essential component, a drug-containing inside layer covering the core, an intermediate layer which covers the inside layer and contains a cationic polymer soluble or swellabl e at a pH of 6.6 or below, and an outside layer which covers the intermediat e layer and contains an anionic polymer soluble at a pH of 7.0 or above.
The Green MED Initiative

The project in brief_x000D_
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The approach to waste management as well as the common values of the European Union and the Mediterranean Partner Countries are based on three principles: waste prevention, recycling and re-use, improvement of final disposal and waste monitoring. The success of the strategy is highly dependent on the effective implementation of unified actions at Mediterranean level creating opportunities to exchange best practices, share knowledge and raise awareness on the importance of waste recycling. In addition the move towards long-term environmental sustainability shall also be supported by legislative frameworks enforcing waste recycling._x000D_
These are the aims of GMI, which represents a pioneer effort of six Mediterranean countries to develop a cross-border incentive based recycling program and communication campaign targeting 200 schools and universities._x000D_
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Specific objective_x000D_
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To develop a cross-border, incentive based, recycling system to promote environmentally sustainable practices at a grass root level - mainly schools and universities - using a state of the art technology platform, supported by an awareness and communications program.
Revalidation in Sport and Exercise Medicine: a UK perspective

The era of professional self regulation in medicine is over. In 2006, it was recognised in the UK Chief Medical Officer's report, ‘Good doctors, Safer patients,’ that an enhanced system of quality assurance and performance management of doctors was required, not only for the profession but to protect the safety of patients.1 From this developed a proposal for five-yearly revalidation of doctors, which is to have two elements, relicensing and recertification. The former, relicensing, began in November 2009. Doctors in the UK are required to hold a licence to practise, which sits alongside their General Medical Council (GMC) registration. Licensure is required by all doctors currently undertaking those professional activities that were previously restricted by law to doctors registered with the GMC.2 Relicensing is the process set up to demonstrate that doctors are practising in accordance with generic standards of practice broadly based upon the guidance provided by the GMC in Good Medical Practice.3

The purpose of this editorial is to bring into focus the requirements for recertification of those doctors practising Sport and Exercise Medicine in the UK. Before considering the specific requirements, it is important to understand that the purpose of revalidation is to ensure that doctors who are registered and have a licence to practise are up to …
Współczesne tendencje w rozwoju form rekreacyjnych i turystycznych

New solutions in the field of recreation and tourism are constantly being researched so as to meet the needs and expectations of a contemporary man. The most frequent factors shaping new trends in recreation and tourism are: demographic factors, economic factors, the style and quality of life, awareness and education, development of technology, pace of applicating new innovations and globalization (including consumerism). In the following publication various forms of recreation and tourism have been described, which – according to the authors – are increasingly in need on today’s market. Forms of recreation, as presented here, are very popular and include Nordic walking, sailing with its variants, skiing, dancing, aerobics and aqua fitness. As for tourism, it is becoming increasingly popular among children and adolescents. Tour operators modify classic programs of youth camps to meet the needs of young customers. Tourism of people with disabilities is also growing nowadays, as well as of single people/ singles, health tourism(including: spa and wellness, medical), shopping, space, sexual tourism, and others. New and more interesting offers will probably appear on the market of recreation and tourism. This is, among others, due to continuing changes in lifestyle and desire to learn new experiences and yet undiscovered sites or types of physical activity.
Dielectric barrier discharges used for the conversion of greenhouse gases: modeling the plasma chemistry by fluid simulations

The conversion of methane to value-added chemicals and fuels is considered to be one of the challenges of the 21st century. In this paper we study, by means of fluid modeling, the conversion of methane to higher hydrocarbons or oxygenates by partial oxidation with CO2 or O2 in a dielectric barrier discharge. Sixty-nine different plasma species (electrons, ions, molecules, radicals) are included in the model, as well as a comprehensive set of chemical reactions. The calculation results presented in this paper include the conversion of the reactants and the yields of the reaction products as a function of residence time in the reactor, for different gas mixing ratios. Syngas (i.e. H2 + CO) and higher hydrocarbons (C2Hx) are typically found to be important reaction products. (Some figures in this article are in colour only in the electronic version)
Use case for european robotics in ophthalmologic micro−surgery

EurEyeCase combines cutting−edge European robotic technology and creates an integrated setup for the very challenging use case of vitreoretinal eye surgery. Nowadays, a selected number of highly−skilled ophthalmologists are treating large numbers of patients that suffer from various types of vitreoretinal eye diseases. The majority of these intra−ocular interventions lie on or even beyond the boundaries of human skills as they pose extreme requirements in terms of manipulation and positioning precision. As a result, current treatments are characterized by moderate success rates and even an inability to adequately treat some common diseases. As a consequence, a large group of patients is left untreated or receives suboptimal treatment only. Robotic technology can and is likely to put an end to the current status−quo. Starting from existing hardware, knowledge and IP and in close collaboration with medical partners, EurEyeCase will build up and validate a convincing robot−assisted operation suite, which will help surgeons in treating a selection of particular demanding vitreoretinal procedures including the treatment of retinal vein/artery occlusion through cannulation and epiretinal membrane treatment. Current laboratory setups will be studied in detail, augmented and tailored for successful integration into the surgical workflow. Novel sensing technologies will be further developed and integrated with advanced control methods to deliver unprecedented levels of safety and performance. In-depth evaluation of the setup in different directions, i.e, performance, usability and clinical relevance, as well as the first steps to transfer the most challenging developments to the next phase of product development are key aspects of the project. EurEyeCase will demonstrate how medical robotics technology can boost success rates of urgent and critical surgical interventions and paves the way for novel promising treatment methods with demonstrated improvements in patient outcome.
Towards smarter means of production in european manufacturing smes through the use of the internet of things technologies

The proportion of the manufacturing industry is currently decreasing in developed European countries’ GDP. Industry 4.0 - also called smart manufacturing, digital industry or industry of the future – provides several technological responses to the challenging competitive market. Indeed, the integration of the Internet of Things and related components - Cyber-Physical Systems (CPS), Digital Security, Cloud Computing and Big Data - in manufacturing SMEs will improve efficiency and flexibility in production and consumption. However, it requires a more integrated and cooperative approach due to the high interdisciplinarity which has been introduced. Above all, not all manufacturing companies, and in particular SMEs, have access to smarter means of production, due to costs and efforts in the integration and implementation, possible aversion or readiness to ICT technologies, and other obstacles related to cyber and physical security. The IoT4Industry project connects 3 Information and Communication Technologies (ICT) clusters having strong competences in IoT with 4 Advanced Manufacturing clusters having access to tool manufacturers and manufacturing SMEs in order to encourage cross-border and cross-sectorial collaboration between SMEs from these two sectors. Starting from the analysis of needs in manufacturing SMEs from diverse sectors in Europe (aerospace, automotive, medicine, ...) on the one hand, and the IoT technology offer on the other hand, the project will put in place favourable framework conditions to enable matchmaking and encourage the creation of smarter manufacturing tools and their integration in manufacturing SMEs. A hundred of support cases involving SMEs corresponding to different development stages (feasibility, prototyping, demonstration) will be selected through a call for proposals to receive funding and support, in view of further developing this new industrial value chain in European SMEs and improve their competitiveness on the global stage.
Development of a high-resolution method to monitor structural changes of regulatory rnas and therapeutic oligo-nucleotides directly in-cell.

MicroRNAs (miRNAs) are master regulators in cells with a complexity yet to be unraveled. By targeting one or more messenger RNAs (mRNAs) they affect a vast number of biological processes and are associated with a broad spectrum of diseases, including cancer. This makes them potential candidates for cancer-diagnostics and -therapeutics. This opportunity can only be fully exploited by a better comprehension of how and when each mRNA is targeted by a miRNA, a fact, which is currently still poorly understood. Besides regulatory RNAs, synthetic “anti-sense” oligonucleotides (AONs) are currently tested as cancer drugs. Progress in this field has been slow due to unspecific off-target-effects i.e. the lack of understanding, of the mechanism of AONs targeting mRNAs. This project focuses on overcoming this lack of knowledge of the targeting process. To understand the intermolecular interactions occurring in the cell we will, for the first time, monitor the molecular structure and structural changes (dynamics) of nucleotides (miRNAs as well as AONs) in the living cell, and link these in-cell structures to the molecule’s targeting function. Combining existing knowledge of the host in structural and molecular biology of miRNAs with the experience in methods development in Nuclear Magnetic Resonance (NMR) of the experienced researcher (ER), we will develop a set of robust and reliable in-cell NMR methods to determine cellular concentration, structure and dynamics within the cell at high resolution. The scope of the method will be demonstrated on: (i) a miRNA, miR-34a, which targets more than 50 different mRNAs, related to cancer and other cellular processes, as well as (ii) an AON drug candidate in collaboration with AstraZeneca. This project will benefit drug development against various diseases and will enable the ER to contribute to solving today's health problems and develop further towards becoming a future group leader on the interface of research in academia and industry.