SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Q-value customized ablation (custom-Q) versus wavefront optimized ablation for primary myopia and myopic astigmatism

Comparison between treatment with wavefront optimized and custom-Q laser-assisted in situ keratomileusis (LASIK) ablations. Our study included 400 eyes of 200 patients divided into two equal groups. All patients were treated for myopia and myopic astigmatism with LASIK. The first group was treated with wavefront optimized ablation and the second group with custom-Q ablation. They were examined preoperatively and postoperatively to assess asphericity, image quality, and other classical outcome parameters. The wavefront optimized ablation group comprised 200 eyes with a mean spherical equivalent refraction (SE) of −5.2188 diopters (D) (range: −1.15 to −10.50 D); the mean Q-value changed from 0.30 preoperatively to 0.06 postoperatively. The custom-Q ablation group also comprised 200 eyes with a mean SE of −5.1575 D (range: −1.35 to −9.00 D); the mean Q-value changed from 0.32 preoperatively to 0.03 postoperatively. A statistically significant difference in postoperative change in Q-values (P = 0.02) and in postoperative visual acuity (P = 0.42) between the two groups was noted. There was no difference between the two groups regarding refractive correction. There was a marginally significant change in BSCVA (best spectacle-corrected visual acuity) between the two groups, and less impairment in the corneal asphericity in the custom-Q group.
Derived symplectic geometry and applications

We propose a program that aims at providing new developments and new applications of shifted symplectic and Poisson structures. It is formulated in the language and framework of derived algebraic geometry after Toën–Vezzosi and Lurie. 

On the foundational side, we will introduce the new notion of shifted symplectic groupoids and prove that they provide an alternative approach to shifted Poisson structures (as they were defined by the PI together with Tony Pantev, Bertrand Toën, Michel Vaquié and Gabriele Vezzosi). Along the way, we shall be able to prove several conjectures that have recently been formulated by the PI and other people. 

Applications are related to mathematical physics. For instance: 
- We will provide an interpretation of the Batalin–Vilkovisky formalism in terms of derived symplectic reduction. 
- We will show that the semi-classical topological field theories with values in derived Lagrangian correspondences that were previously introduced by the PI are actually fully extended topological field theories in the sense of Baez–Dolan and Lurie. 
- We will explain how one may use this formalism to rigorously construct a 2D topological field theory that has been discovered by Moore and Tachikawa. 

Quantization problems will also be discussed at the end of the proposal. 

This project proposal lies at the crossroads of algebraic geometry, mathematical physics (in its algebraic and geometric aspects) and higher algebra.
Identification of Distinct Tumor Subpopulations in Lung Adenocarcinoma via Single-Cell RNA-seq

Single-cell sequencing, which is used to detect clinically important tumor subpopulations, is necessary for understanding tumor heterogeneity. Here, we analyzed transcriptomic data obtained from 34 single cells from human lung adenocarcinoma (LADC) patient-derived xenografts (PDXs). To focus on the intrinsic transcriptomic signatures of these tumors, we filtered out genes that displayed extensive expression changes following xenografting and cell culture. Then, we performed clustering analysis using co-regulated gene modules rather than individual genes to minimize read drop-out errors associated with single-cell sequencing. This combined approach revealed two distinct intra-tumoral subgroups that were primarily distinguished by the gene module G64. The G64 module was predominantly composed of cell-cycle genes. E2F1 was found to be the transcription factor that most likely mediates the expression of the G64 module in single LADC cells. Interestingly, the G64 module also indicated inter-tumoral heterogeneity based on its association with patient survival and other clinical variables such as smoking status and tumor stage. Taken together, these results demonstrate the feasibility of single-cell RNA sequencing and the strength of our analytical pipeline for the identification of tumor subpopulations.
Adiposity and blood pressure among 55 000 relatively lean rural adults in southwest of China

Abstract Obesity is a strong determinant of blood pressure. Uncertainty remains, however, about which indices of adiposity most strongly predict blood pressure, particularly among those who were relatively lean, such as those from rural China. We analyzed cross-sectional data on 55 687 (38.3% men) participants aged 30–79 years who were enrolled into the China Kadoorie Biobank from a rural county in southwest of China during 2004–2008. Measured body mass index (BMI) and waist circumference (WC) were related to blood pressure in multivariable linear regression analyses. The overall mean values of BMI, WC, systolic blood pressure (SBP) and diastolic blood pressure (DBP) were 23.3 kg m −2 , 78.0 cm, 129.2 mm Hg and 77.2 mm Hg, respectively. There was a strongly positive, and apparently linear, relationship of BMI and WC with blood pressure, with 1 s.d. higher BMI associated with 4.3/2.3 mm Hg higher SBP/DBP and 1 s.d. WC associated with 3.8/2.1 mm Hg ( P &lt;0.0001). Additional adjustment for WC only slightly attenuated the association of BMI with blood pressure, whereas additional adjustment for BMI almost completely eliminated the association of WC with blood pressure. Our findings suggest that in relatively lean Chinese adults, general adiposity is more strongly assciated with blood pressure than central adiposity.
Integrated urban waste-managment model

As EU societies become wealthier they create more waste. OECD estimates that every EU citizen generates 550kg solid waste per year and this number is likely to increase to 640kg by the year 2020. To address the rising waste stream, urban areas need effective municipal solid waste management (MSW) concepts that not only build upon innovative new technologies (e.g., in the recycling field), but also make use of new forms and sources of financing as well as new conceptual approaches (e.g., ways to extend producers’ responsibilities and to involve citizens). While EU legislation is a backbone to support this process, the further development of the MSW management concepts and their enforcement lies within the responsibility of local and regional authorities. Overall objective / Objectif général The operation “IUWMM - Integrated Urban Waste Management Model” unites public sector decision makers, expert organisations and universities to develop effective, flexible and practical tools for integrated MSW management. In addition, partners want to increase awareness among public sector decision makers, explore the potential to obtain EU funding for MSW management, and encourage long-term networking among the partners and with other national and EU-wide networks. Expected results / Résultats attendus The operation provides participating organisations with the operational knowledge and practical tools to deal with and optimise integrated MSW-management concepts and to adapt them to suit the regional needs. The operation thus increases the effectiveness of MSW, promotes a coherent approach to integrated MSW management across the EU, supports the harmonized implementation of EU policies, and has positive impacts on the environment. Activities include the identification of state-of-the art techniques for MSW management, the joint development of good-practice models and their adaptation to the needs of the participating regions. Based on a series of international workshops and policy forums, partners harmonize MSW management concepts and tools and elaborate handbooks on the key elements of optimal integrated MSW management. Partners also establish an "EU MSW Management Platform" and develop regional action plans for all ten participating EU regions.
BELT INSTALLATION TOOL

A belt installation tool (10) for installing a flexible belt on a pulley. The tool (10) comprises a belt bearing surface (11) comprising a ramp having a large radius. The ramp (11) is connected to a side of a pulley adjacent to a pulley groove. The ramp (11) also comprises a surface (13) substantially normal to the ramp (11). In use, a belt is loosely placed on the ramp (11) with the ramp at one end of the pulley rotation. As the pulley is rotated, the ramp (11) and belt move with the pulley. As the pulley is rotated, the ramp (11) progressively moves to a position under and supportive of the belt. The normal surface (13) substantially simultaneously aligns the belt with the pulley groove. As the pulley rotates further, the ramp (11) supports the belt while it is trained into the pulley groove. As the pulley rotation is completed, the tool (10) disengages from the belt. Two tool may be used on opposing sides of a pulley to further facilitate installation of a belt.
Households and mutual fund investments: Individual characteristics of investors behaving like contrarians

Abstract We investigate characteristics of household investors stating they would increase shares in a mutual fund in a situation where this fund has exhibited a negative past performance. Hence, we investigate characteristics of investors behaving lite contrarians. We use a survey methodology to examine the effects of risk tolerance, perceived competence, and of being informed on households’ contrarian behavior. To investigate the stability of these characteristics we test our hypothesis in three scenarios: (1) scenario without consideration of market conditions, (2) bull market scenario, and (3) bear market scenario. Findings show that risk tolerance and perceived competence leads to a contrarian buying behavior. The results show that these effects are significant also in bull and bear markets, thus that these characteristics are stable. The findings further show that being informed explains contrarian buying behavior only when no consideration is given to current market conditions. Thus, this characteristic could be considered unstable.
Multifractal characterization of plunger pump vibration signal through improved empirical mode decomposition based detrended fluctuation analysis

Promptly and accurately detecting the plunger pump fault in the hydraulic system is a serious issue in terms of improving reliability and decreasing accidents. A main work is analyzing the character of the collected samples. We used an improved empirical mode decomposition (EMD) based multifractal detrended fluctuation analysis (MFDFA) to extract the multifractal characters. The current method utilizes intrinsic mode functions (IMFs) selection and Kolmogorov — Smirnov test (K-S test) in the detrending procedure. The IMFs selection is used to deal with the undesired IMFs, and the two-sample K-S test works on each IMF and Gaussian noise to detect the noise-like IMFs. The proposed method adaptive to the nature of data and weakening the effect of noise make this approach work well for the non-stationary signal from the real system. We used the proposed method on the plunger pump vibration signal in the hydraulic system to verify the present of multifractal.
Unacceptable Results with an Accepted Soft Tissue Filler: Polyacrylamide Hydrogel

All injectable volumizing agents and fillers may be associated with immediate or delayed complications (overall rate, \1%) [1]. The complication rate is directly related to the technique of injection as well as to the properties of the injected material. With increased persistence of the material, the possibilities of serious complications become more dependent on the inherent physiochemical characteristics of the material rather then on those of the injection technique. Polyacrylamide is used for protein separation in molecular biology [2]. The clinical use of polyacrylamide gel (PAG) as an injectable filler started as Interfall in the Ukraine in 1983. In small quantities, the gel is well tolerated and slowly absorbed by the body (t1/2, 20 years). Different preparations of polyacrylamide hydrogels have unique characteristics, although they all are a combination of a hydrophilic polyacrylamide and nonpyrogenic water. The PAGs discussed in the article by Manafi and colleagues have very different characteristics in terms of the gel concentration. Interfall (Interfall Ltd., Kiev, UA) is a hydrogel with a variable gel concentration of 3.5% to 9%. The latest PAG that has undergone PMA submission to the Food and Drug Administration (FDA) is Aquamid hydrogel [3], a consistent 2.5% cross-linked polyacrylamide gel manufactured by Contura (Denmark). Aquamid (Contura International, Switzerland) is a gel with a constant PAG concentration of 5%. When the safety profile and efficacy of an injectable material is evaluated, all of its unique characteristics must be discussed so an appropriate conclusion can be drawn. In the article by Manafi and colleagues, the patient basis was biased in the conclusion drawn. Only patients experiencing unsatisfactory results and complications of polyacrylamide hydrogel injections were included in their study. Three different preparations of PAG materials were included, yet the effect of the gel concentration on the complication rate was not discussed. An in-depth discussion on the relationship of the volume injected (200 ml/ breast for case 2 vs. 5 ml/lips for case 1) would have been welcome because our experience and clinical data in relation to permanent and semipermanent fillers supported it [1]. Although this article is of clinical interest, the conclusion drawn is not based on the data presented. Recent data [3, 4] from multicenter double-blind studies of 315 and 101 patients, respectively, have shown injections of polyacrylamide hydrogel for soft tissue augmentation at 12 and 24 months to be safe, efficacious, and without adverse soft tissue reactions. In the United States, PMA has submitted Aquamid hydrogel to the FDA.
Novel colostral fractionation process

A method ( 100 ) and a system ( 200 ) for processing mammalian bodily fluids to isolate target peptides and proteins. The method can include the steps of passing a mammalian bodily fluid through at least one ion exchange column ( 204 ). The ion exchange column can include an anionic resin and/or a cationic resin. The ion exchange column can be selected to remove large particles at a first pH level selected to remove such large particles at a maximum fluid pressure of 30 pounds per square inch (psi), for example less than 10 psi. The large particles can be released from the ion exchange column with a rinse solution having a pH selected for releasing the large particles. The pH of the fluid then can be adjusted to be a value less than 5.0, and the fluid can be filtered with a microfilter or ultrafilter ( 210 ).
HEATING SYSTEM AND PROCESS FOR MANUFACTURING SAME

The invention relates to a heating system (1) for a powertrain or a component thereof as well as to a process for manufacturing same. In order to design a device of said type that can be inexpensively integrated into an existing system, at least one heating element (4) for actively electrically heating a powertrain or a component thereof is combined with or provided in a pre-existing part (2) for thermal and/or acoustic shielding.
Software-improved range resolution for oceanographic HF FMCW radar

The high-frequency (HF) oceanographic radar system located at the coast is well-known as a tool for synoptic on-line mapping. Recently oceanographic radar systems have been officially recognized by the International Telecommunication Union (ITU) to have their own frequency bands. However, the assigned spectral bandwidth for radar signals is quite narrow. It leads to loosing the required range resolution. To avoid this disadvantage new high-resolution processing techniques can be applied. The signal processing sequence is considered in order to improve target range resolution by simple software modification. A test example of high-resolution technique for range processing is shown using measured signals of oceanographic HF frequency modulated continuous wave (FMCW) radar.
ROULETTE WHEELS

A roulette wheel (1) has a central, rotatably-mounted disc (15) with conical surface (12) that is coupled via friction wheels (20) to rotate about a common axis with, but in the opposite sense to, the peripheral ring (13) having numbered ball-capture pockets (14), of a rotatably-mounted disc (16) . The surface (12) is textured with regular indentations and this together with the contra-rotation- of the disc (15) retards a ball which having been launched from a ring (7) of the bowl-housing (2) of the wheel (1), passes onto the surface (12) through the pocketed ring (13) before falling back into one of the pockets (14) . The ring (7) is releasable from the housing (2) for replacement, and a crown (23) at the top of a central spindle (11) of the wheel (1) is recessed to receive a ball (24) for testing against a magnet (25) in confirming absence of ferromagnetic material. A spirit-filled vial may be used in the crown (23) for levelling the wheel (1) .
Restoring trust in the cyber space: a systems security proposal

Fueled by a string of high profile attacks and recent revelations
about unprecedented cyber surveillance, interest in systems security
is rising-not just among industry and governments, but even among
individual citizens across Europe. Corporate organizations worry about
the viability of their businesses, nation states about cyber attacks
by other nation states or terrorist groups, and citizens about the
trustworthiness of the ICT infrastructures. 
The long list of recent security incidents is eroding people's trust
in the digital economy and shows that more research is needed.

Unfortunately, expertise is fragmented  across many places, while the
exchange of knowledge is lacking. If one group specializes in
code-reuse attacks and another in embedded systems, ideally they
should team up to detect code-reuse vulnerabilities in embedded
devices. Today, however, the flow of ideas is limited to publications
and ad-hoc collaborations. A more efficient exchange would occur if a
researcher temporarily joins the other group to collaborate directly on-site.

Over the past few years Europe has created 
several world-class research centers in systems security. They
publish in the most prestigious venues and have a significant impact
on both the scientific community and society at large. Nevertheless,
in terms of numbers, most top groups are still  in the US and the ability to
collaborate with them would be a tremendous boost for security
research in Europe.


We plan to foster such collaborations by supporting researchers from
European institutes to spend time with their American counterparts in
top universities. We will gather the research results in a repository
that links all the exchanges and provides a valuable input for
collaborative projects in itself.  We will focus our research efforts
on both advanced attacks (e.g., exploits, malware, and exfiltration
techniques), and defenses (e.g., developing secure software and
protecting resource-constrained devices).
Innovative oxygen-free wine bottling process

The equilibrium between senses and biochemistry of wines can be compromised by the presence of a residual amount of oxygen inside the bottles, affecting the wine microbiology equilibrium and its conservation. In fact, the bottling phase is considered as one of the most critical steps in the entire winemaking process because it can affect the wine quality and features with severe economic consequences for the entire business. Furthermore, the use of sulphites and other preservatives in food and beverage industry currently represents a critical issue, due to their unwanted health effects.
With the aim to improve the overall wine making sustainability, during the last 2 years the “foodtech” start-up company D.R. WINE Tech, supported by ENTER, developed an innovative bottling technology system: RiCaMo. This technology drastically reduces the amount of residual oxygen in the bottle through a patented retractable straw system under gaseous nitrogen, allowing to: 
-monitor the oxygen content during all the filling phases
-reduce the amount of preservatives, like sulphites (-30/60%) and other additives
-produce a high-quality wine with a longer shelf life
-improve bottling volume scale-up of 25%
-reduce wastes (-15% in terms of wine product and glass bottles)
-foster the biological, biodynamic and natural wine production
-support also small producers
-meet the needs of wine makers, retailers, experts and consumers, at international level
RiCaMo innovative filling machine has reached TRL7 and the 14 months European project will bring it to a comprehensive industrialized wine bottling system, through 6 pilots to exploit and test the machine for its market uptake, besides the validation of different business models (direct sale, mobile service and rental). RiCaMo will reach the European and global market within 3 years, providing 32% ROI and about € 1.130.000 turnover by 2022 for D.R. WINE Tech, considering about 70 sold RiCaMo machines and 200 rentals.
Selection of RFID solution provider

Purpose The purpose of this paper is to provide a comprehensive framework to help managers of a business enterprise effectively evaluate candidate RFID solution providers and then select the most suitable one. Design/methodology/approach The selection of an RFID solution provider is modeled as a new hybrid fuzzy multi‐criteria decision making problem. The proposed decision model is based on integration of Monte Carlo simulation with fuzzy analytic hierarchy process (AHP) and fuzzy Technique for Order Preference by Similarity to Ideal Solution (TOPSIS) methods. In addition, an illustrative case is used to exemplify the proposed approach. Findings A quantitative methodology based on a structured framework, for the selection of the most appropriate RFID solution provider. Practical implications This research study is a very useful source of information for managers of a business enterprise in making decisions about evaluation and selection of RFID solution providers or RFID system integrators. Originality/value This study addresses the evaluation and selection of RFID solution providers for the managers of a business enterprise and proposes a new hybrid decision‐making methodology for the problem.
TOURISM COMPANY T2C_43

THE PLAN CONSISTS OF THE CREATION OF A WELLNESS CENTER, PURCHASE OF FURNITURE AND EQUIPMENT FOR THE PREPARATION OF A SPA