SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Decentralised diminished mineralization  incineration unit for dewatered sewage sludge lends resource efficient low-carbon electricity generation

Sewage treatment and the management of the waste is a major cost factor for communities, as sewage treatment plants are often the biggest consumers of electrical energy (share up to 20%). Energy, in particular electricity, is also a valuable resource. Its rational use saves not only money but also resources and helps to reduce CO2 emissions. Through the prohibition of the dumping of untreated sewage sludge and discussions on limitations of its agricultural exploitation, many wastewater treatment plant operators, wastewater associations and disposers must develop and implement new concepts for the treatment of sewage sludge.

It is therefore obvious to try to use sewage sludge as a fuel for energy production. Solutions have already been developed for larger communities. Smaller, especially rural municipalities still spend the sewage sludge remains on agricultural land because technologies for energy recovery from sewage sludge are so far not available in matching orders of magnitude up to 1 MW of thermal power capacity.

The project aims at developing a marketable technology within 24 months consisting of a smart “in-cycle” system for energy-efficient, low-cost, low-carbon generation of electricity from the non-fossil fuel: pasty sewage sludge in the range 400 kW to 1 MW thermal capacity. 
The scale of the proposed technology should correspond to the throughput data of the upstream system, avoiding all concerns of logistic, transport, collecting, storage, deposing, pre-treatment of the sewage sludge; (a typical input from 480 to 1000 kWth is considered).
Additionally, this proposed process should represent an affordable alternative to conventional routes of sewage sludge treatment, with their high release of GHG-emissions and a significant contribution to reduce GHG-emission of the necessary disposal service. 
The feasibility study developed in phase 1 will examine open technical, economic, organisational and legal issues.
Virtual materials market place (vimmp)

VIMMP facilitates and promotes the exchange between all materials modelling stakeholders for the benefit of increased innovation in European manufacturing industry. 

VIMMP will establish an open-source, user-friendly, powerful web-based marketplace linking beneficiaries from different manufacturing industry sectors with relevant materials modelling activities and resources. To enable a seamless and fully integrated environment, VIMMP is built on solid taxonomy and metadata foundations, including those centred on materials models, software tools, communities, translation expertise and training materials. VIMMP is a true marketplace, offering a substantial boost to all providers of tools and services; integrating modelling platforms based on Open Simulation Platform (OSP) standards that will be pursued in collaboration with the EMMC. Thus, any software owner can easily integrate models and certify codes to adhere to OSP standards. The Translator function will be supported by novel, collaborative tools that use metadata to combine models on an abstract logical level. OSP standards enable Translators and End User to build and deploy workflows quickly. 

VIMMP contributes novel avenues for coupling and linking of models, which will be validated in the context of three overlapping industry applications: personal goods, polymer nanocomposites and functional coatings. Data repositories relevant to modelling will be developed and integrated in VIMMP, including a novel input parameter repository for mesoscopic model, also materials properties and associated validation data. VIMMP will comprise a full set of education and training resources relevant for a wider range of manufacturing industry. VIMMP users will profit from lowering risk and upfront cost, greater speed and agility of deploying materials modelling and realising the wide range of demonstrated economic impacts.
Regions for Climate Protection: toward Governance, from Knowledge to Action

In the global context of fighting against climate change, the European Union has committed itself to reduce its greenhouse gas emissions by at least 20% by 2020. The main decisions are taken at the European and national levels but the results have to be achieved in the field. The regional and local levels have therefore a crucial role to play. The starting point of the project is a study on greenhouse gas monitoring methodologies in EU regions carried out in September 2006 by some of the project partners. To go further, the objective of the project is to improve the capacity of regions to build and apply greenhouse gases reduction policies, in order to contribute to climate protection.

The main objective brings in 2 more specific objectives:
> enable regions to efficiently monitor and observe greenhouse gases
> develop regional policies for greenhouse gas mitigation using good governance processes (governance being defined in par.2.1.2)
As part of the project, we also plan to strenghten the dialogue between regions and the EU on climate change policies and their implementation in particular through the Committee of the Regions.

The partnership of the project gathers 11 complementary partners representing 9 Regions (out of which 4 are supported by their regional agency) and 1 international association of energy agencies and regions , with a balanced coverage of the EU Member States from a political and geographical point of view.

The three knowledge areas that will be developed by partners and shared as part of the project are: 1) monitoring and observing greenhouse gases, 2) developing regional policies and action plans for greenhouse gas mitigation, 3) implementing strong regional governance. The project will elaborate assessment methodologies and produce manuals on the three areas, based on the exchange of experience on best practices that can then be used by policy makers.
More regions will be able to benefit from the work done in the project, through the project webportal and other dissemination activities.

The outputs of the project will include identifying best practices on regional climate change policies, addressing climate protection regional policies and preparing implementation plans on regional climate change policies. The project will allow to transfer successfully best practices, to improve regional climate change policies, to increase the capacity of the staff members of the partner regions and to create a network of regional greenhouse gas observatories as a standing working group within an existing network of regions and energy agencies (FEDARENE). In the short-term, the project will enable regions to set up greenhouse gas observatories, develop efficient climate change policies and use regional governance processes to do so. In the medium term, it is expected that greenhouse gas emissions will be significantly reduced.
Effect of vitamin D deficiency and supplementation on myocardial deformation parameters and epicardial fat thickness in patients free of cardiovascular risk

Vitamin D deficiency is associated with impaired myocardial deformation parameters and cardiovascular disease (CVD). Increased epicardial fat thickness (EFT) is also associated with increased risk of CVD. The aim of the study is to evaluate the effect of vitamin D deficiency and supplementation on myocardial deformation parameters and EFT. The study population consisted of 50 patients with vitamin D deficiency who were free of cardiovascular risk (mean age: 42.6 ± 8.9 years, 37 female). Patients were treated with oral administration of vitamin D3. Myocardial deformation parameters and EFT were evaluated before and after treatment of those patients. Vitamin D levels significantly increased after treatment (30.5 ± 10.5 vs. 9.9 ± 5.3 nmol/l, p < 0.001). There was no significant difference between conventional echocardiographic parameters before and after treatment. Baseline EFT was significantly higher than post-treatment measurements (35.2 ± 8.0 vs. 27.5 ± 5.6 mm, p < 0.001). Post-treatment myocardial deformation parameters were also significantly higher than baseline measurements. Baseline vitamin D levels correlated with baseline EFT and left ventricular global longitudinal strain (LV-GLS). Post-treatment vitamin D levels also correlated with post-treatment EFT, body mass index, and LV-GLS. Baseline vitamin D level was an independent predictor of baseline LV-GLS (p = 0.002). Patients with impaired LV-GLS had significantly lower vitamin D levels than patients with normal LV-GLS (6.6 ± 3.8 vs. 11.0 ± 5.3 nmol/l, p = 0.005). Baseline vitamin D level was also an independent predictor of baseline impaired LV-GLS (p = 0.010). Vitamin D supplementation has beneficial effects on myocardial deformation parameters and EFT. Moreover, baseline vitamin D levels are a predictor of impaired LV-GLS.
LIGHTING DEVICE COMPRISING LUMINOPHORE BODY ON HEAT SINK

The lighting device comprises a heat sink (12) and at least one luminophore body (13), wherein the at least one luminophore body (13) is arranged with the rear side (14) thereof on the heat sink (12) and is covered with a light-transmissive layer (16) on the front surface (15) to be irradiated of said at least one luminophore body, said light-transmissive layer having a thermal conductivity at least equal in magnitude to that of the luminophore body (13).
Pattern-Based Development and Management of Cloud Applications

Cloud-based applications require a high degree of automation regarding their IT resource management, for example, to handle scalability or resource failures. This automation is enabled by cloud providers offering management interfaces accessed by applications without human interaction. The properties of clouds, especially pay-per-use billing and low availability of individual resources, demand such a timely system management. We call the automated steps to perform one of these management tasks a “management flow”. Because the emerging behavior of the overall system is comprised of many such management flows and is often hard to predict, we propose defining abstract management flows, describing common steps handling the management tasks. These abstract management flows may then be refined for each individual use case. We cover abstract management flows describing how to make an application elastic, resilient regarding IT resource failure, and how to move application components between different runtime environments. The requirements of these management flows for handled applications are expressed using architectural patterns that have to be implemented by the applications. These dependencies result in abstract management flows being interrelated with architectural patterns in a uniform pattern catalog. We propose a method by use of a catalog to guide application managers during the refinement of abstract management flows at the design stage of an application. Following this method, runtime-specific management functionality and management interfaces are used to obtain automated management flows for a developed application.
ENHANCING TREATMENT OF HIF-1 MEDIATED DISORDERS WITH ADENOSINE A3 RECEPTOR AGONISTS

The present invention relates to the use of adenosine receptor agonists, preferably A3 receptor agonists, either alone or in combination with other agents for the treatment, prevention and/or management of diseases or disorders associated with under­expression of HIF-1 a and/or decreased HIF-1 a<I/>activity (e.g., ischemic related disorders). The methods of the invention are directed to methods of reducing tissue damage (e.g., substantially preventing tissue damage, inducing tissue protection) resulting from ischemia orhypoxia. The invention provides methods for treating, preventing and/or ameliorating one or more symptoms of hypoxic or HIF-la related disorders by administering an A3 receptor agonist either alone or in combination with other agents.
Current direct – swappable container waterborne transport battery

The transport sector contributes to almost a quarter of Europe’s greenhouse gas (GHG) emissions. Compared to other sectors, such as agriculture or energy industries, it is the only sector with emissions higher than that of 1990. Waterborne transport emissions represent around 13% of the overall EU greenhouse gas emissions from the transport sector. Moreover, waterborne transport emissions could increase between 50% and 250% by 2050 under a business-as-usual scenario, undermining the objectives of the Paris agreement.  The challenge for a large-scale adoption and implementation of batteries for waterborne transport is mainly related to the high costs of the battery systems and cells. 

The Current Direct project addresses these challenges by proposing an innovative lithium-ion cell optimized for waterborne transport, using novel manufacturing techniques allowing for a consistent cost reduction compared to the current market prices. Additionally, a swappable containerized energy storage system optimized for cost and operation in the waterborne transport industry will be developed. 

The overarching aim of the Current Direct project is to develop and demonstrate an innovative interchangeable waterborne transport battery system and EaaS Platform in an operational environment at the Port of Rotterdam at TRL7 that facilitates fast charging of vessels, fleet optimization and novel business models. The Current Direct project is dedicated to (i) significantly reduce the total cost of waterborne transport batteries, (ii) cut GHG emissions of the marine transport sector through electrification of vessel fleets, (iii) increase the energy density of waterborne battery cells and (iv) trigger investments for innovation, job and knowledge creation in the European marine transport and battery sector.
Effects of safety behaviors on fear reduction during exposure

The use of safety behaviors has been considered one of the primary maintaining mechanisms of anxiety disorders; however, evidence suggests that they are not always detrimental to treatment success (Milosevic & Radomsky, 2008). This study examined the effects of safety behaviors on behavioral, cognitive, and subjective indicators of fear during exposure for fear of spiders. A two-stage design was used to examine fear reduction and approach distance during an in vivo exposure task for participants (N=43) assigned to either a safety behavior use (SBU) or no safety behavior use (NSB) condition. Overall, both groups reported significant and comparable reductions in self-reported anxiety and negative beliefs about spiders at posttest and 1-week follow-up. Participants in the SBU group approached the spider more quickly than did participants in the NSB condition; however, participants in the SBU condition showed a small but significant decrease in approach distance at follow-up. These results call for a reconceptualization of the impact of safety behaviors on in vivo exposure.
Research and Development Centre for HSM technology in railway and automotive applications

The main objective of this project is to create a R & D centre and equip it with the necessary R & D infrastructure in order to develop an innovative service for the production of thin-walled structures in the railway and automotive industry made of selected metal alloys that meet stricter requirements for narrow tolerances of shape, dimensions, surface roughness and high mechanical properties, including fatigue strength and corrosion resistance, designed for special applications in various industrial sectors, including railways and automotive. The project will strengthen the company’s ability to carry out R & D work through planned investments in new R & D equipment, equipment and other necessary equipment to develop a new service. The aim of the project will be to purchase new fixed assets, including a horizontal machining centre, a thermally stabilised measuring chamber, a spindle, a pressure washer, a deburring vibration machine and a scan and measurement probe.
COllaborative framework for energy EFFICIENT SME systems

CO-EFFICIENT is aiming to advance innovation and already available technologies for energy efficiency and use of renewable resources, in operations and production processes of Mediterranean SMEs. The project consortium believes that there are important organisational, financial and technological obstacles, which impede the advancement of SMEs. Especially if compared to large companies, SMEs are generally slow to adopt energy efficient solutions. One of the crucial problems is that there is not enough communication and coordination between the R&D sector and SME systems, which evidently prevents technology and know-how transfer. The premise, on which this project is based, is that a permanent collaborative framework for energy efficiency and use of renewable resources linking SMEs, the R&D sector, as well as other institutional stakeholder in the Mediterranean area, will be able of improving collaboration between SMEs and the R&D sector and inducing important behavioural and technological changes in the field of energy efficient operations and production processes. The main objective of this framework will be the set-up of a living lab environment, active in all partner countries in which SMEs as final users and R&D organisation as the main developers will collaborate to develop new solutions for better use of energy in production and operations. The salient feature of living labs as such is that they seek to put the final users of innovations in the centre of the product/service development process, which assures a solution customised to user needs. This is what makes living labs appropriate for the customisation of solutions to SMEs. While work package 3 will be focused on the set-up of the framework and methodology for living lab creation, work packages 4 and 5 will each implement one international living lab, comprised of 5 local pilots, respectively. The first international living lab, implemented within WP4, will develop eServices for SMEs in order to improve the energy efficiency of operations, especially in the context of supply chain relationships. Specifically, eServices will address three energy efficiency related fields: distributed planning and re-planning, business document exchange, and transport consolidation. In WP5, the international living lab will collaboratively develop a Frame of reference for energy efficiency and use of renewable resources in production and operations. It will support SMEs in the identification of key production processes and operations that could be improved as far as energy efficiency or the use of renewable resources is concerned. The Frame of reference will be comprised of a mapping methodology, indicators to monitor processes and procedures, benchmarks, and best-practice cases. Apart from these core actions, an important emphasis will be put on accelerating the implementation of already available solutions in the field of energy efficiency and use of renewable resources through intensive dissemination.
2,6-Conjugated Bodipy sensitizers for high-performance dye-sensitized solar cells

Abstract A series of novel 2,6-conjugated Bodipy metal-free organic dyes (UY5–8) with phenothiazine (PTZ) moiety as electron donor for the dye-sensitized solar cells (DSSCs) have been designed and synthesized. The optical, electrochemical properties and photovoltaic performances are extensively investigated. The structure–property relationship shows that the introduction of various auxiliary conjugated spacers and anchoring groups are favorable to changing the efficiency of DSSCs. Among these dyes, UY7 comprised of furan with lower resonance energy as linker and cyanoacetic acid unit as electron acceptor possesses a flatter structure and longer electron recombination lifetime. Hence, a DSSCs using UY7 showing best photovoltaic performance with a short-circuit photocurrent density (Jsc) of 13.64 mA cm−2, an open-circuit photovoltage (Voc) of 590 mV and a fill factor (ff) of 0.66, corresponding to an overall conversion efficiency (η) of 5.31% under 100 mW cm−2 simulated AM 1.5 G solar irradiation. This is the best reported result in the solar cell with a Bodipy dye as photosensitizer.
Polyclonal neural cell adhesion molecule antibody prolongs the effective duration time of botulinum toxin in decreasing muscle strength

This study aimed to investigate if the effective duration time of botulinum toxin A (Btx-A) could be prolonged by polyclonal neural cell adhesion molecule antibody (P-NCAM-Ab). 175 male SD rats were randomly divided into three major groups: control group (n = 25), Btx-A group (n = 25), and P-NCAM-Ab groups. P-NCAM-Ab groups were composed of five sub-groups, with 25 rats each in the dose-response study. Muscle strength of rat lower limbs was determined using a survey system. The expressions of muscle-specific receptor tyrosine kinase (MuSK) and neural cell adhesion molecule (NCAM) were determined by real-time polymerase chain reactions (RT-PCR) and western blotting (WB). The muscle strength was significantly decreased by Btx-A in Btx-A/P-NCAM-Ab groups compared with normal control group. Besides, the muscle strength of P-NCAM-Ab group was significantly decreased compared with the Btx-A group. The recovery time of muscle strength in P-NCAM-Ab group was significantly longer compared with Btx-A group. RT-PCR and WB assay showed that PNCAM-Ab delayed the increase of MuSK and NCAM after Btx-A injection. P-NCAM-Ab prolongs the effective duration time of Btx-A in decreasing muscle strength, which could provide a novel enhancement in clinical application.
Implementation of contrast-ultrasound dispersion imaging for better prostate cancer care

Prostate cancer (PCa) causes 1/5 of new cancer cases and 1/10 of cancer deaths in western males. Timely diagnosis is crucial to enable effective treatment, but this is hampered by the inadequacy and cost of the available diagnostics based on multiple systematic biopsies, which cause discomfort and health risks because of their invasiveness. Moreover, they fail to provide accurate cancer localization, resulting in either over- or under-treatment. A new diagnostic method is thus needed that is accurate and cost-effective. 

Our ambition is to provide patients with accurate diagnosis of PCa by ultrasound imaging. Because ultrasound equipment is affordable and widely available, our method will save lives and cost by enabling noninvasive, timely diagnosis. Over the past years, through a synergic effort of technical and clinical research, we have developed contrast-ultrasound dispersion imaging (CUDI), a revolutionary option to determine cancer location and aggressiveness by detection and characterization of cancer angiogenesis. Our results in 150 patients confirm the accuracy and clinical value of the method.

With this project, we will take CUDI to the next level, establishing the basis for its clinical and commercial translation. To this end, we will realize a commercially-viable software implementation, accounting for user experience, clinical workflow, and regulatory compliance. This project will build on a strong network of international collaborations with key opinion leaders in PCa diagnostics and treatment. We will also account for patient experience via the Dutch Prostate Cancer Association. The establishment of a dedicated start-up driving the valorization activities will provide an additional boost towards the clinical implementation of CUDI.

Our experienced project team combines complementary expertise from academia, industry, and clinic, establishing a solid basis for the valorization and clinical translation of CUDI.