SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
Cellulose Diacetate-g-poly(p-dioxanone) Co-polymer: Synthesis, Properties and Microsphere Preparation

A novel biodegradable graft co-polymer based on cellulose diacetate (CDA) and poly(p-dioxanone) was synthesized by ring-opening polymerization of p-dioxanone (PDO). The molecular structure of co-polymers was characterized by one- and two-dimensional NMR. The graft co-polymers with different lengths of PPDO side-chains could be controllably synthesized by changing the in-feed ratio of CDA/PDO. It was found that the PPDO content had great effect on the thermal transition behavior, crystallization ability and thermal stability of the graft co-polymer. The in vitro degradation rates of CDA-g-PPDO were higher than that of linear PPDO due to their lower crystallinity. Moreover, porous microspheres of graft co-polymers with a diameter of about 5 μm, prepared through the solvent evaporation of water-in-oil emulsion (W/O), indicated it may have potential applications in drug-delivery systems.
Advanced visual and geometric computing for 3d capture, display, and fabrication

The project will create a leading European-wide doctoral Collegium for research in Advanced Visual and Geometric Computing for 3D Capture, Display, and Fabrication (EVOCATION). The Collegium will train the next generation of creative, entrepreneurial and innovative experts who will be equipped with the necessary skills and competences to face current and future major challenges in scalable and high-fidelity geometry and material acquisition, extraction of structure and semantic information, processing, visualization, 3D display and 3D fabrication in professional and consumer applications. In the future, the ESRs will lead research and development of new visual and geometric computing methods in the widest variety of applications, ranging from industrial design to humanities, from medical training to urban assessment, and from creative industries to education methodologies. The EVOCATION network of public and private entities will be naturally multidisciplinary and multi-institutional and will: (a) promote, through domain-specific challenges, the culture of open science and multidisciplinary research applied to concrete problems of the real world, in strict cooperation with end users in engineering, science and humanities; (b) advance the state-of-the-art in geometry and material acquisition, geometry processing and semantic feature extraction, interactive visualization, computational fabrication, and high-bandwidth/3D display systems; (c) bridge complementary approaches for cost-effective data digitization, visualization, fabrication, and display through the integration of different methodologies in the 3D capture, processing and fabrication pipeline; (d) demonstrate the feasibility and efficiency of scalable cost-effective end-to-end techniques to virtually and physically capture and create objects with complex shape and appearance; (e) increase awareness of the benefits of advanced visual/geometric computing technology in both professional and consumer domains.
Approaches for strengthening causal inference regarding prenatal risk factors for childhood behavioural and psychiatric disorders

The risk of childhood behavioural and psychiatric diseases could be substantially reduced if modifiable risk factors for these disorders were identified. The critical period for many of these exposures is likely to be in utero as this is the time when brain development is most rapid. However, due to confounding and other limitations of traditional epidemiological studies, identification of causal risk factors has proved challenging and on the whole research in this area has not been fruitful.In this review, we highlight several alternative approaches including; comparisons across settings, the use of negative controls and natural experiments, which includes migration studies, studies of individuals conceived using in vitro fertilisation and not least Mendelian randomisation. We have illustrated these approaches using examples of behavioural and psychiatric disorders.By having these approaches outlined together in one review, researchers can consider which of these methods would be most suitable for their study question. We have particularly focussed on Mendelian randomisation, as this is a relatively novel concept, in doing so, we have illustrated the concept and discussed the implementation and the limitations of this approach.
The Inequitable Tax Benefits of Adoption

This Comment examines the two provisions of the Internal Revenue Code under which taxpayers may defray expenses incurred in adopting a child. First, under Internal Revenue Code § 137, taxpayers may exclude from income qualified adoption expenses paid or reimbursed by the taxpayer’s employer pursuant to an adoption assistance program. There is no benefit gap under the exclusion-from-income provision; the value is identical to taxpayers regardless of income. Second, under Internal Revenue Code § 23, an adoptive family receives a credit against tax liability to help discharge adoption-related expenses. Because this credit only discharges positive tax liability, only higherincome taxpayers are fully benefitted by the credit. Taxpayers without sufficient tax liability in the current year may carry forward unused portions of the credit for up to five years. However, simple present value analysis shows that, by carrying forward unused portions of the credit, these families receive less of a benefit than do families with higher income who are able to immediately claim the full credit. This benefit gap increases as family income decreases. Families without tax liability are not benefitted by the adoption credit. The amount of the adoption credit is indexed annually for inflation, but this indexation only increases the benefit gap between higherand middle-income taxpayers. This Comment proposes multiple solutions to the current inequitable tax benefit paradigm, and it ultimately proposes a † After this Comment was selected for publication, but before it could be printed, Congress significantly changed the adoption tax credit. These changes are contained within the “Patient Protection and Affordable Care Act,” Pub. L. No. 111-148, signed into law on March 23, 2010. See H.R. 3590 § 10909, available at http://frwebgate.access.gpo.gov/cgibin/getdoc.cgi?dbname=111_cong_billsd J.D., Liberty University School of Law, 2009; B.S. in History, Iowa State University, 2004. Many thanks to my wife, Chelsea, for her support. 136 LIBERTY UNIVERSITY LAW REVIEW [Vol. 4:135 new business tax credit for businesses that provide adoption benefits to their employees.
TOUCH SWITCH WITH DIMMABLE BACKLIGHTING

A touch sensor for controlling intensity of lighting electrically connected thereto, the touch sensor including a touch sensor interface for detecting a touch of a user, a power supply connected to the touch sensor for controlling the intensity of the lighting, and a backlight behind the touch sensor interface, and including a plurality of light sources for illuminating different portions of the touch sensor interface.
A review of robotic mechanisms for ultrasound examinations

Purpose – This paper aims to review the mechanical characteristics of the robotic mechanisms developed for ultrasound examinations. This will help to extract those mechanical features which together can produce a design with superior functionality. Design/methodology/approach – Following an introduction regarding ultrasound examination, this paper discusses the concept of robotic ultrasound imaging and classifies the mechanisms in terms of their power trains used for robotic and haptic devices which assist physicians to perform ultrasound imaging on patients. A set of mechanical characteristics which together can generate a superior design is also presented. Findings – The present paper shows that the robotic devices developed so far can perform ultrasound examinations. Each design with its own advantageous characteristics, and their simultaneous implementation in a new design, will create a robotic device with improved performance. Originality/value – This paper provides a detailed review of the developments of the robotic systems for ultrasound examinations and some guidelines for new designs with improved functionality.
Xinfeng capsule improves pulmonary function in ankylosing spondylitis patients via NF-κB-iNOS-NO signaling pathway

To study changes in the nuclear factor-κB p65 (NF-κB p65)-inducible nitric oxide synthase (iNOS)-nitric oxide (NO) signaling pathway and the effects of Xinfeng capsules (XFC) in patients with ankylosing spondylitis (AS).One hundred twenty patients with AS were randomly divided into an XFC group and a Salazopyrin group. Sixty health subjects were included as a normal control group. In the two treatment groups, pulmonary functional parameters, forced vital capacity (FVC), forced expiratory volume in 1 second (FEV1), maximal voluntary ventilation (MVV), peak expiratory flow (PEF), forced expiratory flow at 25% of forced vital capacity (FEF25), forced expiratory flow at 50% of forced vital capacity (FEF50), and forced expiratory flow at 75% of forced vital capacity (FEF75) were determined. Enzyme linked immunosorbent assays were used for detection of the serum oxidative stress indexes, NF-κB p65, iNOS, NO, reactive oxygen species (ROS), reactive nitrogen species (RNS), malondialdehyde (MDA), superoxide dismutase (SOD), catalase (CAT), total antioxidative capacity (TAOC) and interleukin-4 (IL-4), IL-10, IL-1β, and tumor necrosis factor-α (TNF-α) contents. Westergren's method was used for determination of erythrocyte sedimentation rate (ESR). High-sensitivity C-reactive protein (Hs-CRP) was detected with a 7060 full-automatic biochemical analyzer (Hitachi, Japan).The clinical therapeutic effect in the XFC group was significantly superior to that in the Salazopyrin group (P < 0.01). Compared with the normal control group, FEV1, MVV, PEF, FEF50, FEF75, SOD, CAT, TAOC, IL-4, IL-10 were significantly lower, and NF-κB p65, iNOS, NO, ROS, RNS, MDA, IL-1β, TNF-α, ESR, and Hs-CRP significantly higher in patients with AS (P < 0.01 or P < 0.05). Compared with before treatment, FEV1, MVV, PEF, FEF50, FEF75, SOD, CAT, TAOC, IL-4, and IL-10 were significantly increased, and NF-κB p65, iNOS, NO, ROS, RNS, MDA, IL-1β, TNF-α, ESR, CRP, visual analog scales (VAS), Bath ankylosing spondylitis disease active index, Bath ankylosing spondylitis functional index, and Bath ankylosing spondylitis global index significantly decreased in the two treatment groups after treatment (P <. 0.01 or P < 0.05), with significant differences between the XFC and Salazopyrin groups (P < 0.01 or P < 0.05). Spearman correlation analysis indicated that FEV1, MWVV, PEF, FEF50, and FEF75 were positively correlated with SOD, CAT, TAOC, IL-4, and IL-10, and were negatively correlated with NF-κB p65, iNOS, NO, ROS, RNS, MDA, IL-13, TNF-α, ESR, and CRP.Patients with AS have local pathologic changes in the spinal cord and other joints. They also have decreased pulmonary function, which is negatively correlated with the NF-κB-iNOS-NO signaling pathway, oxidative indexes, and inflammatory factors. XFC improves rigidity and pain in spinal joints and other symptoms, laboratory indexes, and pulmonary function. The mechanism is possibly related to inhibition of the NF-KB-iNOS-NO signaling pathway.
Atomistic Study on the Structure and Thermodynamic Properties of Afe<sub>2</sub>al<sub>10</sub> (A = Th, U)

An atomistic study is presented on the phase stability, interatomic distances and lattice parameters of the new actinide intermetallic compounds AFe 2 Al 10 (A = Th, U). Calculations are based on a series of interatomic pair potentials related to the actinides and transition metals, which are obtained by lattice inversion method. The cohesive energy of AFe 2 Al 10 with two possible structures of YbFe 2 Al 10 -type and ThMn 12 -type are calculated and compared with each other. Calculated lattice parameters of AFe 2 Al 10 are found to agree with reports in the literatures. In particular, the phonon densities of states, vibrational entropy and Debye temperature related to dynamic phenomena are evaluated for the first time.
Between distance and proximity: nature parks and the city in Switzerland

Urban Nature Parks do not exist in Switzerland. A debate regarding their establishment in 2010 petered out. This failure exemplifies a representation of nature in the Swiss parks system, which should stand very far removed from the city. Since the establishment of Parks of National Importance in 2006, human activity has been tolerated under the condition that it is considered rural. Because it is neither wild, with the exception of a few rewilded forests, nor rural, urban nature has no place in this policy. However, the ‘a-urban’ conception of the parks policy in Switzerland does not preclude the existence of close links between cities and nature parks for obvious reasons of spatial and functional proximity. Hence, although the nature parks should be far removed from the cities by definition, they are very close to them by reality. Furthermore, this paradoxical situation is accompanied by the emergence of local solutions, outside the framework of the official regulation of nature parks, for ensuring the conservation of open highly urbanized non-built areas at the outskirts of cities. However those Agglomeration Parks are far from constituting an equivalent alternative to the national strategy with no legal status, an absence of dedicated funding and their very large target gathered under the banner of “open spaces”.
Physicians’ income in Brazil: a study on information sources

OBJECTIVE: Data on physicians' income are relevant for well-informed health policies, both due to their strategic role and the volume of resources that their activities represent to health systems.In Brazil, multiple sources of data measure the income of these professionals, each one with singularities that generate a complex and heterogeneous picture.This study explores the methodological aspects of different data sources, pointing to potentials and limitations to measuring the income of physicians.METHODS: We use the sources' documentation and data on the average monthly income in 2019, by gender and macro region, from four distinct surveys: Continuous Pnad (National Household Sample Survey), RAIS (Annual Listing of Social Information), Medical Demographics, and IRPF (Personal Income Tax).RESULTS: The results confirm the heterogeneity of definitions, variables, and methodologies.The data set can evidence phenomena such as the income difference between men and women.Regional inequalities are evident; however, the data interpretation is less assertive.CONCLUSIONS: Although eventual gaps and discrepancies among sources can limit some strong conclusions, the analysis of different methodologies employed can suggest relevant hypotheses for in-depth studies.
Research on Balling Properties of Pyrite Cinder with High Content of Copper

The balling properties of pyrite cinder (PyC) with high content of copper are researched in this paper. The results indicate that grinding process is an effective way to improve the quality of green balls. Through the measuring of drop strength compressive strength and cracking temperature on pyrite cinder balls, it is found that the best bailing properties of PyC can be obtained under the recommended parameters (the content of grain size of PyC below 75 μm accounts to 95.75% and bentonite dosage is a mass ratio of 2%) and green balls with 5.4 frequency•(0.5m)-1 of drop strength, 15.8 N•each-1 of compressive strength and cracking temperature of about 700 °C are obtained, which can meet the requirements of metallurgical technology.
Uncovering targets for ex vivo expansion of hematopoietic stem cells to enhance cell therapies of blood disorders

Mechanisms of self-renewal in hematopoietic stem cells (HSCs) have been subject to intense studies during the last decades. However, this is still a poorly defined process and very limited progress has been made in the long sought goal of expanding HSCs ex vivo to allow for critical improvements of bone marrow transplantation procedures for cancer patients and potentially a broader use of HSCs in gene therapy and regenerative medicine. The aim of this research program is to systematically identify and characterize regulators of self-renewal in human HSCs and to develop strategies for stem cell expansion. Within the project we will develop novel paradigms for CRISPR (clustered regularly interspaced short palindromic repeats) mediated gene editing in primary human HSCs to enable detailed assessment of gene function. We will further employ forward genetic screening approaches based on both CRISPR/Cas9 gene editing and RNA interference (RNAi) gene silencing to identify regulators of renewal and differentiation in human HSCs. Large numbers of HSCs will be targeted with genome-wide lentiviral CRISPR (sgRNA) and short hairpin RNA (shRNA) libraries. Screening assays for HSC self-renewal will be evaluated in a pooled format and de-convoluted using next generation sequencing, allowing thousands of perturbations to be assayed in parallel. Candidate genes from the screens will be studied further using genetic barcoding and transplantations assays in immundeficient mice to test whether they can be targeted to induce expansion of HSCs ex vivo. Finally, based on our findings, we aim to develop GMP compatible conditions for HSC expansion in preparation for clinical trials involving expansion of umbilical cord blood derived stem cells to treat patients with acute leukemia.
Enhancing Europe’s Global Power: A Scenario Exercise with Eight Proposals

In the present context of intensifying competition between the major trading economies and potentially game-changing technological developments, the European Union is generally seen as the weaker party. Lacking the ‘hard power’ derived from military capabilities, it has laid claim to a ‘soft power’ of normative influence externally, yet even that is only partially utilised. Nor has Europe been able to exercise the power to coerce – ‘sharp power’ – commensurate with its economic weight as a trading bloc equivalent in size and reach to the US or China, its most prominent global competitors. How can Europe strengthen its position, and in what fields? Through a scenario exercise, we develop eight policy proposals aimed at countering Europe´s vulnerabilities and enabling it to assert its sharp and soft power more effectively. Specifically, we consider the feasibility, means and scope for their realisation. Together, they provide a transformative agenda for the EU’s position in the world.
A practical petrophysical model for a source rock play: The Mancos Shale

Recently, the focus in source rock exploration has moved from gas-rich to liquid-rich plays and warrants revisiting “bypassed” hydrocarbon charged source rocks, which were deemed uneconomic when first drilled. In North America’s oil fields, there are thousands of wells with different vintages of nuclear and electrical logs, yet these wells generally lack any advanced logs beyond the traditional triple combo. We have developed a workflow that uses a considerable amount of laboratory measurements made on crushed rock to upscale a petrophysical model based on a triple combo logging suite only. The model divides the field (laterally) in oil window and gas window fairways and (vertically) in petrophysical units. The remaining hydrocarbon generation potential is based on geochemical measurements, such as thermal maturity and total organic carbon content (TOC), from core and cuttings in the area. The petrophysical units reflect major geologic intervals with similar porosity and clay content. The workflow was sequentially built by correlating logs with core measurements, using TOC and maturity for organic matter, X-ray diffraction for mineralogy and grain density, porosity, and water saturation from fluids extraction, for volumetrics. The model is applied to the Mancos Shale (New Mexico, USA), a Cretaceous-age source rock, which includes the Niobrara Formation. The Mancos Shale has been penetrated in various fields while developing conventional sandstone reservoirs. The model is validated with measurements on a core recently acquired in the anticipated high-hydrocarbon-yield window. Petrophysical properties predicted from logs agree well with core measurements in blind tests, demonstrating the robustness of the model despite being based on a basic suite of logs and a simple deterministic approach. This model is now routinely used by the asset team as an automated workflow to generate fairway maps, locate sweet spots, and for landing lateral wells.
CONTRACEPTIVE COMPOSITION WITH REDUCED CARDIOVASCULAR EFFECTS

The present invention relates to a contraceptive method with reduced cardiovascular effects, such as reduced thromboembolism risk, such as reduced venous thromboembolism (VTE) risk and reduced aortic thromboembolism (ATE) risk. The method of the invention comprises administering to a female mammal an effective amount of an estetrol component in combination with a progestogenic component. The method enjoys a favourable profile for thromboembolism compared to currently available methods which employs contraceptives from the so-called second, third or fourth generation.
Hydrogen meeting future needs of low carbon manufacturing value chains

Under the coordination of VERBUND, VOESTALPINE, a steel manufacturer, and SIEMENS, a PEM electrolyser manufacturer, propose a 26 month demonstration of the 6MW electrolysis power plant installed at the VOESTALPINE LINZ plant (Austria). After pilot plant commissioning, the electrolyser is prequalified with the support of APG, the transmission operator of Austria, in order to provide grid-balancing services such as primary, secondary or tertiary reserves while utilising the commercial pools of VERBUND. The demonstration is split into five pilot tests and the quasi-commercial operation to show that the PEM electrolyser is able both to use timely power price opportunities (in order to provide affordable hydrogen for current uses of the steel making processes), and to attract extra revenues from grid services which improves the hydrogen price attractiveness from a two-carrier utility like VERBUND.  Replicability of the experimental results at larger scales in EU28 for the steel industry (with inputs from TSOs in Italy, Spain and the Netherlands) is studied under the coordination of ECN. It involves a technical, economic and environmental assessment of the experimental results using the CertifHY tools.  The roll out of each result is provided by ECN, together with policy and regulatory recommendations to accelerate the deployment in the steel and fertilizer industry, with low CO2 hydrogen streams provided also by electrolysing units using renewable electricity. The plausibility of this roadmap is reinforced at the on-start of the demonstration by the creation of an exploitation company involving the core industrial partners, which starts commercial operations of the Linz pilot plant right after the end of the demonstration. Dissemination targeting the European stakeholders of the electricity, steel and fertilizer value chain nourishes the preparation of the practical implementation of the results in the 10 years following the demonstration’s end.