SIRIS-Lab/unlabelled-sti-corpus huggingface dataset:
PROCESS FOR RECYCLING IONIC LIQUIDS

A method for treating a spent ionic liquid composition includes heating the composition to form a partial decomposition product thereof. The product is separated from composition contaminants and the separated product is reacted with a reactant to regenerate the ionic liquid.
Coupling structure of push lock connector

A coupling structure of a push lock connector includes a first connector, a second connector and a locker. The locker is provided for locking the first connector and the second connector while coupling. The locker includes at least a locking arm, the locking arm includes a locking portion and a block protruding toward inner of the second connector from the locking portion, and the block and the locking arm are arranged at interval. Thereby, the block is snapped in a snapping groove on the first connector while the first connector is inserted in the second connector, and the locking portion is pressed by a sliding housing sleeved on the second connector.
The dynamics and rheology of self-assembled empty liquids: from patchy toy models to anisotropic realistic systems

In this project I plan to investigate by means of numerical simulations the dynamics and rheology of low-density
equilibrium gels made of limited-valence building blocks. I will start with simple toy models of patchy particles
and then add complexity in the form of inner degrees of freedom by investigating systems that undergo a hierarchical
self-assembly process. Examples of such systems are recently synthesised DNA constructs and telechelic star polymers.
The novelty of DELTAS lies in the focus put on the role of the internal flexibility as a tool to tune the dynamics
and the rheology of equilibrium gels. Indeed, the possibility of fine-tuning the structure of these materials
lend themselves well to many applications, ranging from medicine to material science. The project goes one step 
further by proposing to investigate the kinetics, dynamics and mechanical properties of these systems in the 
framework of (flexible) patchy systems. The usage of simple toy models will grant a better understanding of the
phenomenology of these systems. In addition, the realistic systems I plan to investigate will, on one hand, 
establish a stronger link between theory and numerical simulations and experiments and, on the other hand, 
provide a testing ground for the results obtained with toy models.
Rapid Cascade Synthesis of Poly-Heterocyclic Architectures from Indigo

The base-induced propargylation of the dye indigo results in the rapid and unprecedented one-pot synthesis of highly functionalized representatives of the pyrazino[1,2-a:4,3-a']diindole, pyrido[1,2-a:3,4-b']diindole and benzo[b]indolo[1,2-h]naphthyridine heterocyclic systems, with the last two reflecting the core skeleton of the anticancer/antiplasmodial marine natural products fascaplysin and homofascaplysins and a ring B-homologue, respectively. The polycyclic compounds 6-8, whose structures were confirmed through single-crystal X-ray crystallographic analysis, arise from sequential inter/intramolecular substitution-addition reactions, and in some cases, ring rearrangement reactions. Preliminary studies on controlling the reaction path selectivity, and the potential reaction mechanisms, are also described. Initial biological activity studies with these new heterocyclic derivatives indicated promising in vitro antiplasmodial activity as well as good anticancer activity. The chemistry described is new for the indigo moiety and cascade reactions from this readily available and cheap starting material should be more broadly applicable in the synthesis of additional new heterocyclic systems difficult to access by other means.
Fast isolation and expansion of multipotent cells from adipose tissue based on chitosan-selected primary culture

Adipose-derived adult stem cells (ASCs) have gained much attention because of their multipotency and easy access. Here we describe a novel chitosan-based selection (CS) system instead of the conventional plastic adherence (PA) to obtain the primary ASCs. The minimal amount of adipose tissue for consistent isolation of ASCs is reduced from 10 mL to 5 mL. The selection is based on the specific interaction between cells and chitosan materials, which separate ASCs by forming spheroids during primary culture. The primary culture period was reduced from 4 days to one day and more ASCs (ten-fold expansion) were achieved in a week. The average duration for obtaining 1 × 10(7) cells takes about seven days from 5 mL of adipose tissue, compared to 14 days using the conventional PA method from 10 mL of adipose tissue. The replicative senescence of CS-ASCs is not evident until the fifteenth passage (vs. eighth for the PA-ASCs). The obtained ASCs (CS-ASCs) have less doubling time for the same passage of cells and show greater stemness than those obtained from the conventional PA method (PA-ASCs). Moreover, CS-ASCs undergo trilineage differentiation more effectively than PA-ASCs. The greater differentiation potential of CS-ASCs may be associated with the enrichment and maintenance of CD271 positive cells by chitosan selection of primary culture.
HYDROCYCLONE INSTALLATION

The invention relates to an installation for purifying a fibrous suspension, having multiple hydrocyclones (1) arranged adjacent to one another in a row, which hydrocyclones each have at least one feed connection (2), one accepted stock connection (3) and one reject material connection (4), and having at least one supply collecting line (5) which is connected to multiple feed connections (2) and which serves for the feed of the fibrous suspension, and/or having at least one accepted stock collecting line (6) which is connected to multiple accepted stock connections (3) and which serves for the drainage of the accepted stock, and/or having at least one reject material collecting line (7) which is connected to multiple reject material connections (4) and which serves for the discharge of the reject material, wherein the collecting line (5, 6, 7) is of elongate form and the corresponding connections (2, 3, 4) open at the longitudinal side thereof into the corresponding collecting line (5, 6, 7). It is the intention here for deposits in the collecting line (5, 6, 7) to be counteracted in that, at that end of at least one collecting line (5, 6, 7) which follows the final hydrocyclone (1), a fluid or a suspension is conducted at least via a flushing connection (8) into or out of the collecting line (5, 6, 7).
Design of a tiny multi-threaded DNS64 server

DNS64 is going to be an important service (together with NAT64) in the upcoming years of the IPv6 transition enabling the clients having only IPv6 addresses to reach the servers having only IPv4 addresses (the majority of the servers on the Internet today). This paper describes the design of MTD64, a flexible, easy to use, multi-threaded DNS64 proxy published as a free software under the GPLv2 license. All the theoretical background is introduced including the DNS message format, the operation of the DNS64+NAT64 solution and the construction of the IPv4-embedded IPv6 addresses. Our design decisions are fully disclosed from the high level ones to the details.
A CHAIN

A chain such as a roller bush chain comprising a plurality of interconnected chain link members (2,3) is provided with a wiper element (9) that extends at the interface between overlapping portions of the link members. The wiper may be a formation defined on one of the link members or a bush (8) of the chain or may be a separate component between the link members. The wiper has a wiping edge that in use moves relative to a surface of at least one of the members and serves to wipe that surface clean of deposits or debris so as to allow lubricant to penetrate to the bearing between the pin and link members or bush and to reduce the risk of wear.
Positioning tool

A positioning tool for determining the position of the tool in a case downhole. The positioning tool utilizes a detecting unit which includes at least a first magnet and a first sensor in a first plane as well as a second sensor also arranged in the first plane. The first and second sensors are configured to detect changes in a magnetic field generated by the first magnet. The first sensor is arranged at a first distance from the first magnet and the second sensor is arranged at a second distance from the first sensor in the first plane.
REGENERA

The REGENERA thematic network has a main theme of
integrated development in disadvantaged neighbourhoods
with a particular focus on integration of ethnic minorities.
The network, which started in January 2004 with 4 main
sub themes: physical urban renewal, integration of ethnic
minorities, accessibility and transport, organisation of local
communities.
The four themes were split into seminar topics in order
to be able to make meaningful exchanges. The seminar
themes are outlined below:
> Exchange methodology - Milan
> Housing - Glasgow
> Citizen participation - Berlin
> Security - Turin
> Economic development and employment - Sant Adrià
de Besòs
> Changing image - Saint-Étienne
> Multiculturalism - Birmingham
> Health - The Hague
> Rundown condominiums - Budapest
> Education - Pescara
> Governance - Belfast
One of the most innovative elements of the REGENERA
network was the Officer Exchange. Three individuals per city
had the opportunity to spend five days in one of the
REGENERA partner cities in order to deepen their knowledge
of how that city implements the integrated approach to urban
regeneration. This intense method of exchange proved to be
very successful.
Dissecting the chromatin response to dna damage in silenced heterochromatin regions

Cells are continuously exposed to insults that can break or chemically modify their DNA. To protect the DNA, cells have acquired an arsenal of repair mechanisms. Proper repair of DNA damage is essential for organismal viability and disease prevention. What is often overlooked is the fact that the eukaryotic nucleus contains many different chromatin domains that can each influence the dynamic response to DNA damage. Different chromatin environments are defined by specific molecular and biophysical properties, which could necessitate distinct chromatin responses to ensure safe DNA damage repair.
The aim of this proposal is to understand how diverse chromatin domains, and in particular the dense heterochromatin environment, shape the dynamic chromatin response to DNA damage. 
I recently developed locus-specific DNA damage systems that allow for in-depth analysis of chromatin domain-specific repair responses in Drosophila tissue. I will employ these systems and develop new ones to directly observe heterochromatin-specific dynamics and repair responses. I will combine these systems and state-of-the art chromatin analysis with high-resolution live imaging to dissect the DNA damage-associated heterochromatin changes to determine their function in repair -kinetics, -dynamics and -pathway choice.
Deciphering the chromatin dynamics that regulate DNA damage repair in heterochromatin will have broad conceptual implications for understanding the role of these dynamics in other essential nuclear processes, such as replication and transcription. More importantly, understanding how chromatin proteins promote repair will be important in determining how cancer-associated mutations in these chromatin proteins impact genetic instability in tumours in the long run.
METHOD FOR BREAKING DOWN ORGANIC COMPOUNDS IN A LIQUID MEDIUM BY OXIDATION

The invention relates to a method for breaking down, by oxidation, at least one organic compound, such as a carboxylic acid, in a liquid medium at a high concentration, i.e. no lower than 0.05 mol/L, in which the liquid medium is placed in contact, at atmospheric pressure and at room temperature, with a gas that contains oxygen, in the presence of a solid catalyst that enables the breakdown of the organic compound by the oxygen, and the liquid medium is simultaneously subjected to ultrasonic waves.
Empirical demand and welfare analysis

Measurement of consumer welfare is central to economic evaluations. It underlies calculation of price-indices, formulation of tax policies, and environmental and industrial regulation. But existing measurement methods rely on restrictive assumptions about consumer preferences, leading to potentially incorrect conclusions regarding policy-impacts. The proposed project aims to make fundamental contributions to empirical welfare analysis by developing nonparametric approaches, which would avoid such assumptions and thus produce reliable welfare estimates from micro-data. The emphasis will be on welfare-evaluation of price/quality changes in the under-researched but common real-life setting of discrete-choice, e.g., the impact of tuition subsidies for college entrants, fare-hikes for passengers and access to new channels for TV viewers. The project will cover (i) discrete choice with multinomial/ordered/non-exclusive alternatives, (ii) random coefficient choice-models, (iii) settings where one’s choice affects one’s peers’ utilities, and (iv) dynamic choice under uncertainty such as durable-purchase. Welfare analyses in situations (ii)-(iv) are previously unexplored problems and represent ambitious undertakings. Situation (i) has been analyzed only under strong, unsubstantiated assumptions, like quasilinear preferences and extreme valued errors. The key insight driving the project is that welfare calculations require less information than what is needed to identify underlying preference parameters. The project will also develop methods to overcome common data problems like interval-reporting and endogeneity of income. The theoretical results will be complemented by software codes in Stata/R which can be readily used by practitioners. Given the ubiquity of welfare analysis in economic applications and its use in non-academic settings such as merger-analysis, damage calculations, etc., the project is likely to have a substantial impact both in and beyond the academia.
Covid-19 pandemic: an innovative, safe and effective bio-decontamination technology for non-toxic removal of biological agents, including coronavirus

Infectious diseases, such as COVID-19, plague, Ebola, SARS and flu, caused by biological agents, are among the most serious and least predicted threats facing the global community. As we currently experience with the COVID-19 pandemic, bioagents can cause enormous societal and economic damage. Unlike, in the case of chemical, radiological or nuclear incidents, like e.g. in Chernobyl where people could not do much to stop the spread across Europe, in the case of the COVID-19 outbreak, public has a real power to reduce the impact by social distancing, respiratory etiquette, hand hygiene and decontamination in an attempt to flatten the curve.

Current decontamination solutions are suitable for hard surfaces but based on chemicals that cannot be used repeatedly on skin because they are harmful to humans, lead to health complications (hormonal imbalance, allergic reaction and dryness etc.) and damage the environment. There has been a lack of innovation in human-decontamination technologies over the decades and there is a clear need for technologies that can deliver safe, effective and immediate decontamination of human skin. The technological innovation of ABwipe offers a paradigm shift in decontamination.

ABwipe is a unique product, inspired by nature and exploiting the mechanism of pathogen binding. It is made up of a matrix material (cellulose fibres) with attached carbohydrate-protein binders, carefully selected with strong affinities for biothreat agents, including pandemic agents such as influenza and coronavirus. ABwipe not only decontaminates but also captures and contains biological agents. This is a significant capability that reduces the impact, impedes the spread of the infection and allows forensics and diagnostics to identify harmful agents. It is an effective, safer, better and fit for purpose solution for potentially devastating bioagent threat to the society, saving lives, restoring the health of victims and returning contaminated areas to a safe state
Statistical prediction of dielectric single-surface multipactor discharge under mixed field

A statistical method is used to analyze the evolutions of the important physical values in the dielectric single-surface multipactor discharge process with the number of collisions,such as the number of second emission electron,DC field,deposited power on dielectric,and electron transit time,considering the emission energy and launch angles of the emitted electrons,the phase distribution of the RF field.How angles and reflection coefficients affect the multipactor is also studied.The results show that when a certain tilt dc field is imposed,the smaller the reflection coefficient is,and the longer the delay time of the avalanche breakdown and the greater the number of secondary emission electrons in the steady state are.When the dc field is parallel to the surface of the dielectric plate and the RF field is specified,the higher the electric field amplitude is,the longer the delay time of the avalanche breakdown is and the greater the number of secondary emission electrons in the saturation are,but if the amplitude exceeds a certain value,the multipactor will not occur.When the DC is vertical to the surface of the dielectric plate,the higher the electric field amplitude is,the longer the delay time of the avalanche breakdown is and the smaller the number of the secondary electron in saturation are.Similarly,if the amplitude exceeds a certain value,the multipactor will also not occur.
Advanced MRI for carotid plaque imaging

Atherosclerosis is the ubiquitous underling pathological process that manifests in heart attack and stroke, cumulating in the death of one in three North American adults. High-resolution magnetic resonance imaging (MRI) is able to delineate atherosclerotic plaque components and total plaque burden within the carotid arteries. Using dedicated hardware, high resolution images can be obtained. Combining pre- and post-contrast T1, T2, proton-density, and magnetization-prepared rapid acquisition gradient echo weighted fat-saturation imaging, plaque components can be defined. Post-processing software allows for semi- and fully automated quantitative analysis. Imaging correlation with surgical specimens suggests that this technique accurately differentiates plaque features. Total plaque burden and specific plaque components such as a thin fibrous cap, large fatty or necrotic core and intraplaque hemorrhage are accepted markers of neuroischemic events. Given the systemic nature of atherosclerosis, emerging science suggests that the presence of carotid plaque is also an indicator of coronary artery plaque burden, although the preliminary data primarily involves patients with stable coronary disease. While the availability and cost-effectiveness of MRI will ultimately be important determinants of whether carotid MRI is adopted clinically in cardiovascular risk assessment, the high accuracy and reliability of this technique suggests that it has potential as an imaging biomarker of future risk.
Exploiting the tumor proteome activity status for future cancer therapies

Kinases are key regulators of protein activity and phosphorylate thousands of proteins in cells. The phosphoproteome can hence be viewed as a proxy for the proteome activity status of a cell. Dysregulation of the phosphoproteome can cause diseases such as cancer. As a result, kinase inhibitors have become important drugs in oncology and nearly 50 are approved for use in humans. As they typically have a range of targets, there is enormous potential for repurposing these drugs for other cancer entities. To implement this in the clinic, it is important to better understand: i) how the phosphoproteome of an individual tumor can be functionally interpreted, ii) how and to what extent kinase inhibitors modulate the phosphoproteome and iii) which drug is the best fit for modulating the proteome activity status of a particular tumor. This information is only partially or not available from classical cancer diagnostics or genomics. Therefore, the central aim of this project is to show that ground breaking new information for the diagnosis and treatment of cancer patients will come from measuring their tumor proteome activity status (TOPAS) by quantitative mass spectrometry. To this end, the first objective is to show that modulating the TOPAS of cancer model systems by kinase inhibitors functionalizes the phosphoproteome and reveals the cellular mechanisms of action of these important medicines. The second objective is to develop and validate diagnostic drug-, protein- and pathway-centric TOPAS scores able to make treatment suggestions based on the phosphoproteomes of cancer models and tumor tissues. The third objective is to demonstrate, on the example of sarcoma patients, that TOPAS scoring adds value to decision making by molecular tumor boards. Combining the strengths of proteomics and genomics, I aim for building a comprehensive multi-omics view on tumors and will create a ‘virtual tumor board’ in ProteomicsDB to make TOPAS available to the scientific community.
Enhanced in Vivo Delivery of 5-Fluorouracil by Ethosomal Gels in Rabbit Ear Hypertrophic Scar Model

Applying Ethosomal Gels (EGs) in transdermal drug delivery systems has evoked considerable interest because of their good water-solubility and biocompatibility. However, there has not been an explicit description of applying EGs as a vehicle for hypertrophic scars treatment. Here, a novel transdermal EGs loaded with 5-fluorouracil (5-FU EGs) was successfully prepared and characterized. The stability assay in vitro revealed that 5-FU EGs stored for a period of 30 days at 4 ± 1 °C had a better size stability than that at 25 ± 1 °C. Furthermore, using confocal laser scanning microscopy, EGs labeled with Rhodamine 6 G penetrated into the deep dermis of the hypertrophic scar within 24 h in the rabbit ear hypertrophic model suggested that the EGs were an optional delivery carrier through scar tissues. In addition, the value of the Scar Elevation Index (SEI) of 5-FU EGs group in the rabbit ear scar model was lower than that of 5-FU Phosphate Buffered Saline gel and Control groups. To conclude, these results suggest that EGs delivery system loaded 5-fluorouracil is a perfect candidate drug for hypertrophic scars therapy in future.
Color-stabilized electrochromic devices

An electrochromic device comprising: (a) a first substantially transparent substrate having an electrically conductive material associated therewith; (b) a second substrate having an electrically conductive material associated therewith; (c) an electrochromic medium contained within a chamber positioned between the first and second substrates which comprises: (1) a solvent; (2) a cathodic electroactive material; (3) an anodic electroactive material, wherein at least one of the anodic and cathodic electroactive materials is electrochromic; and (4) a color-stabilizing additive, wherein the color-stabilizing additive is electroactive within a normal operating voltage of the electrochromic device; and (d) means associated with the color-stabilizing additive for maintaining an at least nearly colorless electrochromic device while the electrochromic device is in an open circuit and/or zero potential state relative to the same device without the color-stabilizing additive.