Supplementary Figures from MALT1 Inhibition Is Efficacious in Both Naïve and Ibrutinib-Resistant Chronic Lymphocytic Leukemia

<jats:p>&lt;p&gt;Supp. Fig. S1: MI-2 causes a dose- and time-dependent apoptotic induction selectively in primary CLL cells with minimal toxicity to normal B cells. Supp. Fig. S2: Sensitivity to MI-2 is independent of clinical or biological features classically associated with poor outcomes in CLL. Supp Fig. S3: Changes in ALC of patients being treated with ibrutinib&lt;/p&gt;</jats:p>