Supplementary Tables from MALT1 Inhibition Is Efficacious in Both Naïve and Ibrutinib-Resistant Chronic Lymphocytic Leukemia

<jats:p>&lt;p&gt;Supplementary Table S1. Patient characteristics. Supplementary Table S2. Characteristics of patients treated with ibrutinib. Supplementary Table S3. Primers and probes used for digital PCR. Supplementary Table S4. List of genes up- or down-regulated genes by MI-2 in CLL. Supplementary Table S5. Gene sets identified by GSEA that are affected by MI-2.&lt;/p&gt;</jats:p>

section_content: Supplementary Table S4 Down-regulated genes (N=312) Up-regulated genes (N=126)
section_name: Supplementary

section_content: IGHV ZAP70 CLL-01 72 M I N NEG 17p-Mutated NEG CLL-02 56 F II N POS Normal NA POS CLL-03 72 F 0 N NEG +12 Mutated NA CLL-04 61 F I Y NEG 11q NA NA CLL-05 47 M 0 N NEG Normal Mutated NA CLL-06 89 F I N NEG Normal NA NA CLL-07 59 M II N NEG 13q-Mutated NA CLL-08 79F 0 N NEG 13q-Unmutated NA CLL-09 54 M II N NEG 13q-Unmutated NA CLL-10 92M IV N POS 13q-NA NA CLL-11 72M II N NEG 17p-NA NEG CLL-12 58M I N NEG NA Mutated NA CLL-13 67M 0 N NEG 11q Unmutated NEG CLL-14 61F 0 Y NA NA Mutated NA CLL-15 55M II N NEG 13q-Mutated NEG CLL-16 58F II N NEG 11q Mutated NEG CLL-17 72F IV Y POS 17p -Unmutated POS CLL-18 77M NA Y NEG 17p-Mutated NEG CLL-19 72M IV Y NEG NA NEG CLL-20 75M IV Y POS 13q-Unmutated POS CLL-21 75F I N NEG 13q-Mutated NEG CLL-22 69M NA Y POS 17p-Mutated POS CLL-23 41M II N POS 17p-Unmutated POS CLL-24 70M I N NEG 13q -Mutated NEG CLL-25 49M III N NA 17p-Unmutated NA CLL-26 47M I N NEG NA Mutated NEG CLL-27 64M I N NEG 13q-Mutated NEG CLL-28 50M I N NA 11q Unmutated NA CLL-29 46M III N POS NA NA POS CLL-30 61M IV N POS Normal Unmutated POS CLL-31 49F I N NEG 13q-Mutated NEG CLL-32 61F II N NEG 17p-Unmutated NEG CLL-33 67F 0 N NEG 13q-Unmutated NEG CLL-34 47M III N NEG 17p-Mutated NEG CLL-35 67F I N NEG 13q-NA NEG CLL-36 58F IV N POS 13q-Unmutated POS CLL-37 66F I N POS 17p-Unmutated POS CLL-38 57M NA N POS 11q Mutated NA CLL-39 55F NA N NEG 13q-Unmutated NEG CLL-40 63M I N NEG 17p-Mutated NEG CLL-41 39M NA N POS +12 Unmutated POS CLL-42 48M NA N NA Normal Mutated NA Supplementary Table S1

section_name: Supplementary