SII-SWORD/CoKE huggingface dataset:
Protein of unknown function DUF7263 (DUF7263)
Type: Family

This entry represents uncharacterised proteins found mainly in Halobacteria.
LtfC/p132/Gp6, beta-sandwich domain (LtfC/p132/Gp6_b-sand)
Type: Domain

This entry, previously known as DUF7264, represents a domain found in the Minor tail protein Gp6, Collar protein p132, Lateral tail fiber protein C (LtfC) and related phage proteins. This domain folds into a β-sandwich fold with and extended β-hairpin that projects away from it. The minor tail proteins Gp6 are likely involved in the assembly or function of the tail structure in bacteriophages. The collar protein p132 forms the collar structure, which serves as an anchoring point for the side tail fiber protein pb1, suggesting a role in stabilising the tail fibres and ensuring proper attachment to the host cell .

The lateral tail fiber protein C (LtfC) is a component of the DT57C bacteriophage tail tip complex where it forms a dodecameric ring . LtfC adopts a compact, single-domain structure. The LtfC ring is complemented by another lateral tail fibre protein, LtfA. Each of the LtfA monomers is connected to the LtfC assembly in a unique way by augmenting the edges of LtfC β-sheets with two short β-strands and thus completing the LtfC β-sandwich structure.
Domain of unknown function DUF7265 (DUF7265)
Type: Domain

This entry represents an C-terminal domain from a family of uncharacterised phage proteins. This domain has a β sandwich fold.
Protein of unknown function DUF7266 (DUF7266)
Type: Family

This entry represents uncharacterised archaeal proteins.
Protein of unknown function DUF7267 (DUF7267)
Type: Family

This entry represents a family of uncharacterised phage proteins. Structure prediction suggests this protein adopts a rather open conformation of three α helices and a possible β strand suggesting it must interact with other proteins to function.
Protein of unknown function DUF7268 (DUF7268)
Type: Family

This entry represents uncharacterised proteins found mainly in Halobacteria. They are predicted to contain three transmembrane helices and likely associate with the membrane.
Protein of unknown function DUF7269 (DUF7269)
Type: Family

This entry represents uncharacterised proteins found mainly in Halobacteria. They are likely composed mainly of α-helices. These proteins contain a semi-conserved GxWTDDxxAA sequence motif toward their C terminus.
Domain of unknown function DUF7270 (DUF7270)
Type: Domain

This entry represents and uncharacterised family of phage proteins.
Domain of unknown function DUF7271 (DUF7271)
Type: Domain

This domain is found in the homologues of uncharacterised soybean proteins.
Protein of unknown function DUF7272 (DUF7272)
Type: Family

This entry represents a small family of uncharacterised proteins from phage. The structure of this family does not appear similar to any other known protein or family.
Domain of unknown function DUF7273 (DUF7273)
Type: Domain

This entry represents a small family of uncharacterised mycobacterium phage proteins. These proteins adopt a compact three helical bundle domain.
Domain of unknown function DUF7274 (DUF7274)
Type: Domain

This entry represents a family of uncharacterised phage protein domains. The domain adopts a compact β sheet made of six strands.
Domain of unknown function DUF7275 (DUF7275)
Type: Domain

This entry represents the central α helical domain from a large family of uncharacterised phage proteins that typically contain three domains.
Domain of unknown function DUF7276 (DUF7276)
Type: Domain

This entry represents the C-terminal domain from a large family of uncharacterised phage proteins that typically contain three domains.
Domain of unknown function DUF7277 (DUF7277)
Type: Domain

This entry represents the N-terminal domain from a large family of uncharacterised phage proteins that typically contain three domains.
Domain of unknown function DUF7278 (DUF7278)
Type: Domain

This entry represents a domain found various uncharacterised bacterial proteins that according to ECOD adopts a profilin-like fold.
Protein of unknown function DUF7279 (DUF7279)
Type: Family

This family represents a family of uncharacterised proteins from T even phage.
Protein of unknown function DUF7280 (DUF7280)
Type: Family

This entry represents a group of uncharacterised bacteriophage proteins, predominantly from mycobacteriophages and Gordonia phages. Members are typically between 80-130 amino acids in length. It folds into a compact domain composed of a sheet of five β strands with an α helix packed on one side.
Domain of unknown function DUF7281 (DUF7281)
Type: Domain

This domain is found C-terminal in uncharacterised bacterial proteins. It shares some similarity to the C-terminal domain of JetD

.
Cell surface glycoprotein 1/2, DUF7282 (Slg1/2_DUF7282)
Type: Domain

This domain of unknown function is found in Cell surface glycoprotein 1/2 from Haloarcula hispanica (Slg1/2) and similar uncharacterised bacterial and archaeal proteins. Slg1/2 are S-layer proteins. The S-layer is a paracrystalline mono-layered assembly of proteins which coat the surface of the cell . This domain is predicted to adopt a β-sandwich with an Ig-like topology, similar to domains members of

. Some proteins contain multiple copies of this domain.
Protein of unknown function DUF7283 (DUF7283)
Type: Family

This entry represents uncharacterised proteins found mainly in Halobacteria.
Protein of unknown function DUF7284 (DUF7284)
Type: Family

This entry represents uncharacterised archaeal proteins.
Protein of unknown function DUF7285 (DUF7285)
Type: Family

This entry represents uncharacterised archaeal proteins.
Protein of unknown function DUF7286 (DUF7286)
Type: Family

This entry represents uncharacterised proteins found in Euryarchaeota.
Protein of unknown function DUF7288 (DUF7288)
Type: Family

This entry represents a group of uncharacterised archaeal proteins.
Protein of unknown function DUF7289 (DUF7289)
Type: Family

This entry represents a group of uncharacterised archaeal proteins. Their genes occur in pilB/pilC operons.
Domain of unknown function DUF7290 (DUF7290)
Type: Domain

This entry represents a small family of uncharacterised proteins found in enterobacteria phages. The proteins are around 80 residues in length. The proteins assume a compact domain that has four β strands forming a sheet followed by three α helices packed on one side.
Protein of unknown function DUF7291 (DUF7291)
Type: Family

This entry represents a small family of uncharacterised phage proteins. A structure prediction suggests this protein forms a compact α helical domain followed by a disordered region.
Protein of unknown function DUF7292 (DUF7292)
Type: Family

This entry represents a family of uncharacterised phage proteins. These possibly have an N-terminal signal peptide followed by a small compact domain composed of a single α helix packed against a four stranded β sheet.
Protein of unknown function DUF7293 (DUF7293)
Type: Family

This entry represents an uncharacterised protein of approximately 54 amino acids found in T5-like bacteriophages that infect Escherichia coli and Salmonella. Homologues have been identified in several T5-like phages including bacteriophage T5, Salmonella phage vB_SenS_SB13, and Escherichia phage vB_EcoS-26175V. Structure prediction suggests that this protein forms a strand swapped homodimeric arrangement. The dimeric structure forms two four stranded sheets that are connected by two α-helices. The C-terminal of each protein is donated to the sheet made by the other monomer.
Protein of unknown function DUF7294 (DUF7294)
Type: Family

This family of uncharacterised proteins is found in a variety of cyanophages. These proteins adopt of compact domain structure composed of four strands and one α helix.
Protein of unknown function DUF7295 (DUF7295)
Type: Family

This entry represents an uncharacterised protein found in various bacteriophages that infect Salmonella, Escherichia, Shigella, Pantoea and Serratia species. This family includes a member in bacteriophage T5. The function of this protein is currently unknown. Structure prediction does not predict a globular compact fold for this protein.
Domain of unknown function DUF7296 (DUF7296)
Type: Domain

This entry represents a family of domains found in phages that infect a variety of bacterial hosts including Streptococcus, Streptomyces, Pseudomonas and Paenibacillus species. The Domain is typically around 110-130 amino acids in length.
Protein of unknown function DUF7297 (DUF7297)
Type: Family

This entry represents a family of uncharacterised phage proteins. The family includes

which is annotated as a baseplate I protein. Proteins in this family are about 450 residues in length.
Domain of unknown function DUF7298 (DUF7298)
Type: Domain

This entry represents an uncharacterised phage domain. In some members of the family this domain is found at the C-terminal of a longer protein which also contains

.
Protein of unknown function DUF7299 (DUF7299)
Type: Family

This entry represents a small family of uncharacterised phage proteins.
Domain of unknown function DUF7300 (DUF7300)
Type: Domain

This entry represents a small family of uncharacterised phage proteins. These proteins contain a small compact globular domain composed of a four stranded meander followed by a C-terminal α helix.
Protein of unknown function DUF7301 (DUF7301)
Type: Family

This entry represents a small family of uncharacterised phage proteins. These proteins contain a highly conserved RDR/KVL sequence motif that is likely functionally important.
Protein of unknown function DUF7302 (DUF7302)
Type: Family

This entry represents a family of uncharacterised phage proteins that have a small N-terminal domain composed of three β strands and an α helix.
Protein of unknown function DUF7303 (DUF7303)
Type: Family

This family consists of various uncharacterised phage proteins and a few bacterial proteins. The family members range in length from 82 to 229 amino acids, with most in the 180 to 200 amino acid range. They are found in phages that infect Pseudomonas, Xanthomonas, Acinetobacter, Escherichia, Rhodobacter, Sphingomonas, Achromobacter, and Burkholderia bacteria. Bacterial proteins in the family are from Candidatus Macondimonas diazotrophica, Verrucomicrobium sp. GAS474 and Pelodictyon phaeoclathratiforme. The function of these proteins is currently unknown.
Domain of unknown function DUF7304 (DUF7304)
Type: Domain

This entry describes a family of uncharacterised proteins, around 70 amino acids in length, found in mycobacteriophages. The family members share sequence similarity but their function is currently unknown. The domain is found as a single copy in the phage proteins. The domain adopts a compact globular fold with a four stranded β sheet followed by an α helix.
Domain of unknown function DUF7305 (DUF7305)
Type: Domain

This domain is found in uncharacterised prokaryotic proteins most of which likely associated with proteins located in pilBC operon. It is frequently found inserted in

. This domain is predicted to adopt a single-stranded right-handed beta-helix with similarity to ice-binding proteins and other adhesive domains.
Minor capsid protein P11, C-terminal conserved region (P11_C)
Type: Domain

This entry, previously known as DUF7306, represents a conserved region found C-terminal in the Minor capsid protein P11 and related phage proteins. P11 is one of the minor capsid proteins that constitute a network below the outer capsid shell, internal to the major capsid proteins and outside the lipid membrane . P11 plays crucial roles in determining the capsid size and binding neighbouring symmetrons together. The P11 proteins zip together most of the capsomers at the boundary of neighbouring tri- or penta-symmetrons via their C-terminal regions. The C-terminal regions of each P11 protein is located underneath the conjunction of a set of three neighbouring capsomers, gluing these capsomers together . These C-terminal regions are to a large extend unstructured.
Pam3 gp33-like protein (Pam3_gp33-like)
Type: Family

This entry represents a set of uncharacterised phage proteins that are related to the Pam3 phage gp33 protein. This entry also includes uncharacterised bacterial sequences.
Domain of unknown function DUF7308 (DUF7308)
Type: Domain

This domain is found in uncharacterised archaeal proteins most of which likely associated with proteins located in pilBC operon. It is frequently found inserted in

. This domain is predicted to fold into a globular structure with a β-sandwich topology.
Domain of unknown function DUF7309 (DUF7309)
Type: Domain

This entry represents a domain of unknown function found in uncharacterised proteins from bacteria, as well as in some plasmid pRiA4b ORF-3 family of proteins.
Domain of unknown function DUF7310 (DUF7310)
Type: Domain

This entry represents a coiled-coil region found in uncharacterised proteins, mainly from archaea.
Domain of unknown function DUF7311 (DUF7311)
Type: Domain

This domain is found in uncharacterised archaeal proteins.
Domain of unknown function DUF7312 (DUF7312)
Type: Domain

This domain is found in uncharacterised archaeal proteins. It is predicted to fold into a single helix.
Domain of unknown function DUF7313 (DUF7313)
Type: Domain

This domain is found in uncharacterised archaeal proteins. It is predicted to fold into a four-helical bundle and it is likely associated with the membrane.
Domain of unknown function DUF7314 (DUF7314)
Type: Domain

This domain is found in uncharacterised archaeal proteins. It is predicted to fold into an α-helical hairpin and it is likely associated with the membrane.
Domain of unknown function DUF7315 (DUF7315)
Type: Domain

This domain is found in uncharacterised archaeal proteins. It is predicted to fold into an α-helical hairpin and it is likely associated with the membrane.
Protein of unknown function DUF7316 (DUF7316)
Type: Family

This entry represents a small family of phage proteins. These proteins form a confident dimer according to structure prediction. The dimer adopts a novel fold composed of a long four stranded β-sheet with two α-helical elements packed at each end of the twisted sheet. There is quite a bit of structural variability across the family with a variety of alternative elaborations.
Protein of unknown function DUF7317 (DUF7317)
Type: Family

This family includes a group of short archaeal proteins, that are distantly related to

.
Protein of unknown function DUF7318 (DUF7318)
Type: Family

This entry represents uncharacterised archaeal proteins.
Domain of unknown function DUF7319 (DUF7319)
Type: Domain

This domain is found in uncharacterised archaeal proteins.
Domain of unknown function DUF7320 (DUF7320)
Type: Domain

This entry represents an uncharacterised protein found in T4-like bacteriophages. It is found between the cd and pseT genes in the T4 phage genome. The function of this protein is unknown. Structure prediction suggests these proteins have a compact fold composed of five β strands and an α helix.
Domain of unknown function DUF7321 (DUF7321)
Type: Domain

This domain is found in uncharacterised archaeal proteins. It is predicted to fold into a four-helical bundle and it is likely associated with the membrane.
Domain of unknown function DUF7322 (DUF7322)
Type: Domain

This domain is found in uncharacterised archaeal proteins. It is predicted to fold into an α-helical hairpin and it is likely associated with the membrane.
Domain of unknown function DUF7323 (DUF7323)
Type: Domain

This entry represents a small β-barrel domain found at the N-terminal of some phage proteins.
Protein of unknown function DUF7324 (DUF7324)
Type: Family

This entry represents a small putative zinc binding motif found in a small number of uncharacterised phage proteins.
Protein of unknown function DUF7325 (DUF7325)
Type: Family

This entry represents a family of uncharacterised phage proteins that are glycine rich.
Protein of unknown function DUF7326 (DUF7326)
Type: Family

This entry represents a family of uncharacterised phage proteins.
Protein of unknown function DUF7327 (DUF7327)
Type: Family

This entry represents a small family of uncharacterised phage proteins.
Protein of unknown function DUF7328 (DUF7328)
Type: Family

This entry represents a small family of phage proteins. Structure prediction suggests that these proteins form a single long α helix.
Protein of unknown function DUF7329 (DUF7329)
Type: Family

This entry represents a family of uncharacterised phage proteins. Proteins in this family are around 250 residues in length.
Domain of unknown function DUF7330 (DUF7330)
Type: Domain

This entry represents a domain found in uncharacterised proteins, mainly from fungi. This domain may consist of β-solenoid repeats. This entry shows distant similarity to

.
Protein of unknown function DUF7331 (DUF7331)
Type: Family

This entry represents uncharacterised archaeal proteins. They share a semi-conserved YDxxNPXAW sequence motif.
Protein of unknown function DUF7332 (DUF7332)
Type: Family

This entry represents uncharacterised archaeal proteins.
Protein of unknown function DUF7333 (DUF7333)
Type: Family

This entry represents uncharacterised archaeal proteins. They are predicted to fold into an α-helical hairpin.
Protein of unknown function DUF7334 (DUF7334)
Type: Family

This entry represents a small family of uncharacterised phage proteins.
Protein of unknown function DUF7335 (DUF7335)
Type: Family

This entry represents a small family of uncharacterised phage proteins.
Domain of unknown function DUF7336 (DUF7336)
Type: Domain

This entry represents a family of uncharacterised domains found in a variety of phage and bacterial genomes. Structure prediction suggests the domain is composed of a small β sheet of three strands and an α helix. There is some evidence from prediction that these domains might form a dimeric arrangement.
Protein of unknown function DUF7337 (DUF7337)
Type: Family

This entry represents a small family of uncharacterised phage proteins.
Protein of unknown function DUF7338 (DUF7338)
Type: Family

This entry represents a family of uncharacterised proteins from phage. Structure prediction shows the proteins to be composed of an α helical N-terminal domain and a C-terminal domain composed of a 5 stranded β meander.
Domain of unknown function DUF7339 (DUF7339)
Type: Domain

This entry represents an uncharacterised protein domain found in bacteriophage proteins, particularly those infecting Lactococcus species. The domain is approximately 115 amino acids in length. It is found in a small number of bacterial proteins as well.
Domain of unknown function DUF7340 (DUF7340)
Type: Domain

This entry represents the C-terminal zinc binding domain of an uncharacterised family of phage proteins.
Domain of unknown function DUF7341 (DUF7341)
Type: Domain

This entry represents the N-terminal domain of an uncharacterised family of phage proteins.
Protein of unknown function DUF7342 (DUF7342)
Type: Family

This family includes uncharacterised archaeal proteins that contain a HTH domain.
Domain of unknown function DUF7343 (DUF7343)
Type: Domain

This entry represents the HTH domain found in group of uncharacterised archaeal proteins.
Domain of unknown function DUF7344 (DUF7344)
Type: Domain

This is a presumed HTH domain found in a group of uncharacterised archaeal sequences.
Domain of unknown function DUF7345 (DUF7345)
Type: Domain

This is a presumed domain found in uncharacterised proteins from archaea. It may adopt a ferredoxin-like fold.
Protein of unknown function DUF7346 (DUF7346)
Type: Family

This entry represents uncharacterised archaeal sequences containing a presumed HTH domain.
Domain of unknown function DUF7347 (DUF7347)
Type: Domain

This is a presumed HTH domain found at the N-terminal of a group of uncharacterised archaeal sequences.
Domain of unknown function DUF7348 (DUF7348)
Type: Domain

This domain is found N-terminal in a group of uncharacterised archaeal proteins. In some proteins, this domain precedes

and

. It is predicted to fold into a globular α/β structure.
Domain of unknown function DUF7349 (DUF7349)
Type: Domain

This family of uncharacterised proteins is found in various phages that infect bacterial hosts such as Bacillus, Staphylococcus, Enterococcus, Listeria, Lactobacillus, and Brochothrix species. The proteins in the family are typically 75 to 100 amino acids in length. The protein contains a small N-terminal domain represented by this entry followed by a C-terminal disordered region.
Domain of unknown function DUF7350 (DUF7350)
Type: Domain

This domain is found in uncharacterised archaeal proteins. It is predicted to adopt Ig-like fold.
Domain of unknown function DUF7351 (DUF7351)
Type: Domain

This is a presumed domain found at the C-terminal of a group of uncharacterised archaeal sequences, which contain an HTH domain at the N-terminal.
Domain of unknown function DUF7352 (DUF7352)
Type: Domain

This entry represents a family of uncharacterised phage domains. These domains adopt a β-sandwich structure.
Domain of unknown function DUF7353 (DUF7353)
Type: Domain

This domain is found in a group of uncharacterised proteins from Kinetoplastida. It is found on its own or in combination with

. It is predicted adopt a UBA-like α-helical bundle.
Domain of unknown function DUF7354 (DUF7354)
Type: Domain

This domain of unknown function, is found N-terminal in a small group of bacterial proteins. This domain is found in magnetobacterial protein MtxA from Magnetospirillum gryphiswaldense (

). M. gryphiswaldense is a member of a diverse group of aquatic bacteria that have the magnetotaxis ability to align themselves along the geomagnetic field lines and to navigate to a microoxic zone at the bottom of chemically stratified natural water. MtxA was shown to be essential for the magneto-aerotaxis .
Domain of unknown function DUF7355 (DUF7355)
Type: Domain

This entry represents a small family of uncharacterised phage proteins. The family includes the y13F protein from bacteriophage T4

. Structure prediction shows this protein has a compact globular fold composed of three β-strands and two α-helices.
Domain of unknown function DUF7356 (DUF7356)
Type: Domain

This domain is found in uncharacterised plant proteins. It is predicted to adopt a globular structure with similarity to Fibronectin type III-like domains.
Domain of unknown function DUF7357 (DUF7357)
Type: Domain

This domain is found in uncharacterised proteins mainly from fungi. It is predicted to fold into a globular structure with ubiquitin-like topology elaborated with long loops. It is frequently found in combination with

.
Domain of unknown function DUF7358 (DUF7358)
Type: Domain

This domain is found in uncharacterised proteins from plants. It is predicted to adopt an α-helical bundle with ferritin-like topology. This domain is frequently found in combination with

.
Domain of unknown function DUF7359 (DUF7359)
Type: Domain

This entry represents a domain of unknown function found in SPbeta prophage-derived uncharacterized protein (YomG) from Bacillus subtilis (strain 168). This domain may adopt a FN3-like fold and can be found in association with a prophage endopeptidase tail domain (

).
Domain of unknown function DUF7360 (DUF7360)
Type: Domain

This entry represents a domain of unknown function found in SPbeta prophage-derived uncharacterized protein YomG from Bacillus subtilis (strain 168). This domain may can be found in association with a prophage endopeptidase tail domain (

).
Domain of unknown function DUF7361 (DUF7361)
Type: Domain

This entry represents a domain of unknown function found at the C-terminal of SPbeta prophage-derived uncharacterized protein YomG from Bacillus subtilis (strain 168). This domain may be found in association with a prophage endopeptidase tail domain (

).
Domain of unknown function DUF7362 (DUF7362)
Type: Domain

This entry represents a domain of unknown function found at the N-terminal of CHAT domain-containing, such as SwissProt:A0A100JVW6, protein from Streptomyces scabiei. This domain may be found in association with TCAD7 (Pfam:PF19973) and CHAT (Pfam:PF12770) domains.