Title: Lois Griffin
Content:  Lois Griffin is voiced by producer and staff writer, Alex Borstein, who also voices recurring characters such as Asian reporter Tricia Takanawa, Loretta Brown and Lois' mother Barbara Pewterschmidt. Borstein has been part of the main voice cast from the beginning of the series including the pilot, and has been voicing Lois from the start. At the time Family Guy was being developed, Borstein was working in the sketch comedy, MADtv. She was asked to audition by a member of the MADtv staff who was helping MacFarlane develop the show. She had not met MacFarlane or seen any artwork and said it was "really sight unseen". At the time, she was doing a stage show in Los Angeles, in which she played a redhead mother, whose voice she had based 
Title: Griffin family
Content:  anchor Tom Tucker and Lois' father Carter Pewterschmidt. Alex Borstein voices Lois Griffin, Asian correspondent Tricia Takanawa, Loretta Brown and Lois' mother Barbara Pewterschmidt. Borstein was asked to provide a voice for the pilot while she was working on MADtv. She had not met MacFarlane or seen any artwork and said it was "really sight unseen". At the time, she was doing a stage show in Los Angeles, in which she played a redhead mother, whose voice she had based on one of her cousins. The voice was originally slower, when MacFarlane heard it, he replied "Make it a little less annoying  and speed it up, or every episode will last four hours". Seth Green primarily 
Title: Lois Griffin
Content:  one of her cousins from Long Island, New York. She took the voice of the character to the set and use it for Lois. The voice was originally slower, when MacFarlane heard it, he asked her to make it faster and higher. Borstein has noted that the voice of Lois has been changing from the slower original voice to the quicker up tempo voice of the present episodes. There have been occasions where Borstein does not voice Lois, such as in the episode "Road to the Multiverse", where Lois is not voiced by Borstein in a scene and instead was voiced by Japanese actress Kei Ogawa, who was required for a scene where everything in the world was Japanese (she also did the voice of Meg for the scene).
Title: Lois Griffin
Content:  Lois Patrice Griffin (née Pewterschmidt) is a fictional character from the animated television series Family Guy. She is voiced by writer Alex Borstein and first appeared on television, along with the rest of the Griffin family, in a 15-minute short on December 20, 1998. Lois was created and designed by series creator Seth MacFarlane. MacFarlane was asked to pitch a pilot to the Fox Broadcasting Company based on Larry and Steve, a short he made which featured a middle-aged character named Larry and an intellectual dog, Steve. After the pilot was given the green light, the Griffin family appeared in the episode "Death Has a Shadow". Lois is the mother of the Griffin family. She and her husband, Peter, have three children: Meg, Chris, and Stewie, along with the family dog, Brian. Lois is often portrayed as a stereotypical television mother and housewife, despite her admitting to being a recovering methamphetamine addict and a kleptomaniac. Lois has also had several affairs, one of which allegedly resulted in the conception of Chris.
Title: Griffin family
Content:  Lois Patrice Griffin (née Pewterschmidt), voiced by Alex Borstein. Lois is the mother of the Griffin family. Lois's morals are often questionable, as she went through a brief period of kleptomania in the episode "Breaking Out Is Hard to Do", for which she went to prison. She also showed a gambling addiction when the family went to an Indian casino in "The Son Also Draws" during the first season. Various episodes have hinted that Lois is an avid drug user, but this is shown most clearly in "Deep Throats", where she revealed that she smoked marijuana when she was pregnant with Stewie, 
Title: List of Family Guy cast members
Content:  Alex Borstein voices Lois Griffin, Asian correspondent Tricia Takanawa, Loretta Brown and Lois' mother Barbara Pewterschmidt. Borstein was asked to provide a voice for the pilot while she was working on MADtv. She had not met MacFarlane or seen any of his artwork and said it was "really sight unseen". At the time, Borstein performed in a stage show in Los Angeles, in which she played a redhead mother whose voice she had based on one of her cousins. The voice was originally slower (and deeper for the original season), but when MacFarlane heard it, he replied "Make it a little less fucking annoying ... and speed it up, or every episode will last four hours."
Title: Griffin family
Content:  Chris Griffin and Neil Goldman. Green admittedly did an impression of the Buffalo Bill character from the thriller film The Silence of the Lambs during his audition. His main inspiration for Chris' voice was how "Buffalo Bill" would sound if he worked at a drive-thru in a McDonald's (speaking through a PA system). Mila Kunis and Lacey Chabert have both played the voices of Meg Griffin. Chabert voiced Meg Griffin for the first production season (15 episodes). However, because of a contractual agreement, she was never credited. Chabert left the series due to time constraints with her acting role in Party of Five, as well as schoolwork, while Kunis won the role after auditions, a 
Title: Family Guy
Content:  voices for various other recurring and one-time-only characters, most prominently those of the Griffins' neighbor Glenn Quagmire, news anchor Tom Tucker, and Lois' father, Carter Pewterschmidt. Alex Borstein voices Peter's wife Lois Griffin, Asian correspondent Tricia Takanawa, Loretta Brown, and Lois' mother, Babs Pewterschmidt. Borstein was asked to provide a voice for the pilot while she was working on MADtv. She had not met MacFarlane or seen any of his artwork, and said it was "really sight unseen". At the time, Borstein was performing in a stage show in Los Angeles. She played a redheaded mother whose voice she had based on 
Title: Lois Griffin
Content:  Lois Griffin was born to affluent WASP parents, Carter and Barbara Pewterschmidt. It is revealed in the episode "Family Goy" that her mother is actually a Holocaust survivor who concealed her Judaism, though she was raised a Protestant. Lois and the rest of the Griffins live in the fictional city of Quahog, Rhode Island, which is modeled after Cranston, Rhode Island. Lois also speaks with a distinctive New England accent. She primarily works as a housewife throughout the series, though she did give piano lessons in early episodes. Lois has also had various jobs in single episodes such as in "FOX-y Lady", where she becomes the new reporter for Fox News Channel, in "It Takes a Village Idiot, and I Married One", Lois is elected the mayor of Quahog, and in "Call Girl" Lois gets a job doing phone sex. In the episode "Take a Letter", Lois works at the Post Office, where she sarcastically states she is "6,004th in line for the Presidency". Lois retired from boxing with a record of 18–0.
Title: Griffin family
Content:  MacFarlane voices three of the show's main characters, Peter Griffin, Brian Griffin and Stewie Griffin. He has stated that he already knew what kind of voice he was looking for the main characters so it was easier to do it himself. Peter's voice is inspired by the voice of a security guard MacFarlane overheard talking while attending the Rhode Island School of Design. Stewie's voice was based on the voice of English actor Rex Harrison, particularly on Harrison's performance in the 1964 musical drama film My Fair Lady. Brian's voice is MacFarlane's regular speaking voice. In addition MacFarlane provides the voice of various recurring and one-time characters, most prominently those of the Griffin's neighbor Glenn Quagmire, 

Question: who originally voiced lois griffin?
Answer: Alex Borstein.