Question: What are the treatments for Machado-Joseph Disease ?
Answer: Lyme disease is treated with antibiotics under the supervision of a physician.
Source: NINDS

Question: What is the outlook for Machado-Joseph Disease ?
Answer: Most individuals with Lyme disease respond well to antibiotics and have full recovery. In a small percentage of individuals, symptoms may continue or recur, requiring additional antibiotic treatment. Varying degrees of permanent joint or nervous system damage may develop in individuals with late-stage Lyme disease.
Source: NINDS

Question: what research (or clinical trials) is being done for Machado-Joseph Disease ?
Answer: The National Institute of Neurological Disorders and Stroke (NINDS) conducts MJD research in its laboratories at the National Institutes of Health (NIH) and also supports MJD research through grants to major medical institutions across the country. Ongoing research includes studies to better understand the genetic, molecular, and cellular mechanisms that underlie inherited neurodegenerative diseases such as MJD. Other research areas include the development of novel therapies to treat the symptoms of MJD, efforts to identify diagnostic markers and to improve current diagnostic procedures for the disease, and population studies to identify affected families.
Source: NINDS