Question: How many people are affected by Cole disease ?
Answer: Cole disease is a rare disease; its prevalence is unknown. Only a few affected families have been described in the medical literature.
Source: GHR

Question: Is Cole disease inherited ?
Answer: This condition is inherited in an autosomal dominant pattern, which means one copy of the altered gene in each cell is sufficient to cause the disorder. In most cases of this disorder, an affected person inherits the mutation from one affected parent. Other cases result from new mutations in the gene and occur in people with no history of the disorder in their family.
Source: GHR