Question: What is the outlook for Von Hippel-Lindau Disease (VHL) ?
Answer: The prognosis for individuals with VHL depends on then number, location, and complications of the tumors. Untreated, VHL may result in blindness and/or permanent brain damage. With early detection and treatment the prognosis is significantly improved. Death is usually caused by complications of brain tumors or kidney cancer.
Source: NINDS