# Jenjazi

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| Chirwere che Jenjazi |
| --- |
| Mamwe mazita | chirwere che pakinsoni |
|  |
| Ilustiresheni ye Jenjazi na William Richard Gowers (1886) |
| Bazu re sainzi: | Ruambanyuro / Unenanyuro |
| Masimputomu | * Nhetemwa
* kukukuta
* Kuhamba zviporepore
* kukona kufamba
 |
| Ma-Complication | * Urashakumbuko (*dementia*)
* Vufukamoyo (*depression*)
* Netsekanohuru (*anxiety*)
 |
| Kutanga | Zera 60 nepamusoro |
| Chikonzero | Hachizivikanwi |
| Fekita ye njodzi | * *Pesticide exposure*,
* kukwadzwa kwemsoro
 |
| Mutowo werumbondero | zvichienderana nemasimputomu |
| Rumbondero ruri
Differential | * Urashakumbuko ne mwiri-Lewi,
* progressive supranuclear palsy,
* essential tremor
* antipsychotic use
 |
| Kurapa | Mishonga, sejari |
| Mishonga | L-DOPA, maagonisti edhopamini |
| Rumbonderamberi
(*prognosis?*) | tarisiro ye ndaramo inoti makore 7–15 |
| Rudido | 6.2 miriyoni (2015) |
| Ndufu | 117,400 (2015) |

 |

**Jenjazi** (Chingezi: *Parkinson's Disease, PD*) kana Chirwere cheJenjazi chirwere cheuropi chisinga rapike. Chiratidzo chikuru chechirwere ichi ndechekuti murwere anenge achi jenjemera kana kuti kugwagwadza zvakanyanya asina zvaano kwanisa kuita nazvo. Kujenjemara kwacho kwunoitika nguva dzose.

Jenazi chirwere chechinguvarefu kureva kuti chinogarisa nguva yakareba kana hupenyu hwose hwemunhu, chiri mubazi re zvirwere zvinonzi hosha ye dhijeneritivhi (*degenerative disorder*) uye chinotambudza Udzira Mutandi Wepakati (CNS) rinonyanyisa kubata mutandira we uhamba.

Masimputomu anowanzo buda zvishoma nezvishoma, uye nekunyanya kwechirwere, masimputomu asiri e mtandira we mota anowonekawo. Masimputomu anotanga kuoneka inhetemwa, *rigidity*, uporepore we uhamba, uye kukona kutaura. Matambudziko e ungwaru ne maitiro anogona kuitikawo futi, pamwe ne vufukamoyo, netsekanohuru, ne vushayashungu zvese zvinoitika muvanhu vane jenjazi. Hurivari kana urashakumbuko hwe jenjazi runooneka nekuenderera kwe masteji echirwere chacho. Avo vane jenjazi vanogonawo kunetsekana nemitandira yekurara ne kusensa. Masimputomu emota echirwere anopedzisira akonzeresa rufu rwe nyere mu *substantia nigra*, rhijoni yepakati pehuropi, zvichiita kuti dhopamini ipunguke. Rufu rwenyere dzacho hanunyatsonzwisiswa, asi unosanganisa kuunganidzwa kwe mapurotini asina kupeteka-kwazvo mumwiri ye Lewi mumanyuroni. Pamwe chete, masimputomu emota makuru anozivikanwa wo se ujenjazi (*parkinsonism*) kana dovodzano ye Jenjazi.

## Mazwi ashandiswa

* **chinguvarefu** kana **kuroniki** kureva (*chronic*)
* Shoko rechishongrish rokuti dhijeneritivhi ndirorashandiswa, reChivanhu chairo rinodikanwa (*degenerative*)
* **Hosha** kureva (*disorder*)
* **Udzira Mutandi we Pakati (UMP)** kana futi **Dandaudzira re Pakati (DP)** kureva (*central nervous sytem*)
* **Mtandira we Mota** kana **Mtandira we Uhamba** (*motor system*)
* **Hurivara** (kureva *dementia*, kubva pashoko rekuti kurivara rinoreva kukanganwa *forgetfulness*. Kana pane rimwe shoko ngariiswe pamusoro peiri, ndavonga)
	+ **Urashakumbuko** (lose memory) kureva *dementia* - kubva pashoko rokuti kukumbuka (*remember*) mumitauro ye Chibhantu.
* Dhopamini (kureva *dopamine*)
* Kupunguka (*deficiency*)
* Dovodzano ye jenjazi (*parkinsonian syndrome*)
* Mwiri-lewi (lewy bodies)