# Medication

| Medication |
| --- |
| Packages of medication (tilidin) |
| Other names | Medicine, drug, pharmaceutical, pharmaceutical preparation, pharmaceutical product, medicinal product, medicament, remedy, meds |

**Medication** (also called **medicine** or **pharmaceutical drugs**) is the use of legal drugs to treat or cure an illness.

Drugs which are sold freely or do not require a prescription are called over-the-counter (OTC) drugs. It is easy to buy OTC drugs. A doctor must give a prescription for powerful or dangerous drugs. The note from the doctor is called a prescription. These drugs are called prescription drugs, prescription medicines, or prescription only medicines (POM).

## Terminology

There are many different words used to describe things about medications.

### Action

Action is what the medication is supposed to do. It is the helpful effects that the medicine is supposed to have on the body.

Many drugs have more than one action. For example, acetaminophen is an analgesic (it kills pain) and an antipyretic (it makes fevers go away).

### Indication

An indication is a reason why a medication is given.

Many drugs have more than one indication. For example, acetaminophen's indications include pain and fever.

### Contraindication

A contraindication is a reason why a medication should not be given.

Almost all medicines, even over-the-counter medications, have some contraindications. For example, acetaminophen should not be given to people who are allergic to acetaminophen. For these people, acetaminophen is "contraindicated," and another medicine should be used instead. Acetaminophen is also contraindicated in people who have liver disease.

### Dosage

Dosage is how much medication needs to be taken to make the medication do what it is supposed to. Dose can be worked out based on body weight (others in BMI) based on amount of drug (for example a mg of the drug) versus weight of the person (like in kg). Working out dosage like this has helped come up with a LD50 (lethal dose in 50% of the population) for drugs and other chemicals people might eat, and it uses the dose of drug for every kilogram of weight on a person to estimate how much it would take to be toxic to the body as a guess.

Some dosages are based on age. For example, children often need less medication than adults. The mix of the drug or how it is delivered can change based on age, like how different flavours can be used in child, animal (horse for example) or psychiatric medicine (or the dose route changed, such as putting it in apple pudding). Other chemicals might be used in the adult version of a medicine people use to treat specific issues, such as the use of salicylic acid in oral wart gel for adults, which is contravened in children. In tinctures, or a mix of the medicine or medicines, is allowed to be made up of 0.5% alcohol for children under 6, 5% for ages 6-12, and 10% for people aged 12+, according to the FDA.

Dosage is very important because all medicines can be poisons if they are taken in large amounts. If a person takes too much of a medication, they can get very sick or even die. This is called an overdose. For example, taking too much acetaminophen (also called paracetamol, Tylenol, or Panadol) can badly hurt the liver.

Sometimes, normal dosages have to be changed if a person has certain medical problems like kidney failure for example. If someone has to go through surgery then they might not be allowed to drink liquids to avoid adverse effects or failure. A different gas has to be used during surgery in types of operation, like one on the GI tract for example. In these cases it is useful to have taken nothing by mouth before the operation, not just to avoid affecting medications but so the operation does not end in failure.

Cartoon showing how long the list of possible side effects can be
### Adverse effects (side effects)

A person takes a medication because they want it to do certain things. When the medication also does other things that the person did not want, these are called adverse reactions or "side effects". For example, acetaminophen can cause nausea. This is a side effect of acetaminophen.

Adverse effects are side effects that are dangerous or harm the body. For example, in some people, acetaminophen can hurt the liver. This is an adverse effect of acetaminophen.

Most medicines have many possible side effects. This does not mean that anyone who takes the medicine will have those side effects. For example, not everyone who takes acetaminophen gets nausea. A side effect is just a possible effect that a medicine can have on the body.

## Medication names

All medications have a few different names.

### Chemical name

When a medication is first discovered, it is given a chemical name. This name describes the atoms or molecules in the medication. Usually, only scientists use this name.

For example, the chemical names for acetaminophen are N-acetyl-para-aminophenol and para-acetyl-amino-phenol.

### Generic name

Every country has one generic (official) name for every medicine.

In the United States, a medicine is given an official generic name after the Food and Drug Administration (FDA) says it is safe to be sold. For example, acetaminophen is the official generic name used in the United States. (Paracetamol is the generic name used in the United Kingdom and some other countries.)

Sometimes, generic names come from a medicine's chemical name. For example, acetaminophen is named after N-**acet**yl-para-**amino-phen**ol, and paracetamol is named after **par**a-**acet**yl-**am**ino-phen**ol**.

Tylenol 500 mg capsulesPanadol 500 mg tablets
### Brand name

Each company that makes a drug gives that drug a brand name. No other company is allowed to use this name.

For example, in the United States, the most common brand name for acetaminophen is Tylenol. One of the companies that makes acetaminophen (Johnson & Johnson) chose the name "Tylenol" for its acetaminophen. Another company that makes acetaminophen (GlaxoSmithKline) chose "Panadol" as its brand name. Like with most medicines, there are many other brand names for acetaminophen.

### Abbreviations

Some medicines have unofficial abbreviations. For example, acetaminophen is sometimes abbreviated APAP. This comes from the drug's chemical name: N-**A**cetyl-**P**ara-**A**mino-**P**henol.

### All the same medicine

No matter which of these names is used, they all describe the same medicine. For example, there is no difference between N-acetyl-para-aminophenol, acetaminophen, paracetamol, Tylenol, Panadol, and APAP.

## How medications are given

There are many ways that medications can be given. These are called "routes of administration."

For most medications to work, they need to get into the bloodstream. The blood carries the medicine around the body and takes it where it is needed. The way a medication is given affects:

* The path that the medicine takes to get into the bloodstream and how long this takes
* How much of the medicine gets into the bloodstream
* How much of the medicine reaches the tissue where it is needed
* How long the medicine's effects will last

### By mouth

The most common way of giving medicine is by mouth (per os). The medicine comes in a pill or liquid that a person swallows.

When taken by mouth, medication gets into the bloodstream through the digestive system. It takes a while, usually 15–20 minutes, for the medicine to get through parts of the digestive system and get taken up into the bloodstream. Also, a very small amount of the medicine actually gets into the bloodstream. This is because acid in the stomach kills most of the medicine before it can be taken up into the bloodstream.

Medicines taken by mouth often last longer than medicines taken by other routes of administration.

Not every medication can be given by mouth. With some medicines, like insulin, the acid in the stomach will change the medicine or break it down so much that it will not work.

### Into a vein

A person gets medicine through an IV in their hand
Some medicines can be given through a needle placed into a vein. This way of giving medicine is called *intravenous (IV)*.

This is one of the fastest ways to get medicine into the bloodstream. Veins carry blood, so when a medication is given *intravenously*, it goes right into the bloodstream immediately. It takes less than a minute for blood to flow around the entire body. This means that when given intravenously, a medicine will reach the brain within a minute or less. All of the medicine (100%) gets into the bloodstream.

However, IV medications will not last as long as medications given by mouth. This is because the body starts metabolizing medications (breaking them down so the body can get rid of them) as soon as the medicine gets into the bloodstream.

Not every medicine can be given intravenously.

### Into a muscle

Some medicines can be given through a needle placed into a big muscle, like the muscles in the upper arm, thigh, or buttocks. This way of giving medicine is called *intramuscular (IM)*.

When a medicine is given *intramuscularly*, the medicine gets into the bloodstream through smaller blood vessels in the muscles. This takes longer than an IV injection, because the medicine is not being injected directly into a blood vessel. However, the medicine still reaches the bloodstream faster than medicines given by mouth.

Also, not all of the medicine gets into the bloodstream because some of it gets caught in the soft tissue in the muscle and never reaches the blood vessels.

### Breathed in

Some medicines can be breathed in. This way of giving medicines is called *by inhalation* (sometimes abbreviated INH). This can be especially helpful for lung problems like asthma. Asthmatics can sometimes carry around inhalers which deliver a nebulized drug to the body quickly. Since the medicine is breathed right into the lungs, it can start working on the lungs right away.

### Other routes

There are many other routes of administration. For example:

* Into the bone *(intraosseous (IO)).* A needle is placed into a large bone, like the femur (thigh bone), and medicines are given into the bone marrow. Any medicine that can be given into a vein can also be given into a bone. Like with IV medicines, all of the medicine gets into the bloodstream, immediately. IO medicines can only be given by certain medical professionals, like doctors and paramedics.
* Into the rectum *(per rectum (PR))*. Some medicines can be given into the rectum. The medicine does not get into the bloodstream very quickly. This route is mostly used with people who cannot swallow medicines, like very young children or people who are vomiting (throwing up).
* Under the skin *(subcutaneous (sub-q))*. Some special medicines can be given through a needle placed under the skin. For example, insulin is often given this way.
* Into the nose *(intranasal)*. Some special medicines can be sprayed into the nose. When a medicine is given *intranasally*, all of the medicine will go to the brain, immediately. For example, naloxone (which is used to treat opiate overdoses) can be given intranasally.

There are many other routes of administration.

Many medicines can be given more than one way. For example, acetaminophen can be given by mouth, into the rectum, or into a vein.