# Pseudokoliiniesteraasi

| BCHE |
| --- |
|  |
|

| Saatavilla olevat rakenteet |
| --- |
| PDB | Ortologiahaku: PDBe RCSB  |
|

| Luettelo PDB-tunnisteita |
| --- |
| 1P0P, 4AXB, 4B0P, 2XQG, 1XLV, 2WIK, 2WIL, 1P0Q, 1XLU, 4BDS, 2XQF, 2PM8, 2XQK, 4AQD, 4BBZ, 2WID, 2XMB, 1XLW, 2XMC, 4TPK, 2XMG, 2XMD, 3DKK, 3O9M, 2WSL, 2WIJ, 1P0I, 2WIG, 2XQJ, 3DJY, 1P0M, 4B0O, 2XQI, 2Y1K, 4XII, 2WIF, 2J4C |

 |

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| Tunnisteet |
| Aliakset | BCHE, CHE1, CHE2, E1, butyrylcholinesterase, BCHED |
| Muut tunnisteet | OMIM: 177400; MGI: 894278; HomoloGene: 20065; GeneCards: BCHE; OMA:BCHE - orthologs |
|

| Geenisijainti (Ihminen) |
| --- |
|  |
| Kromosomi | Kromosomi 3 (ihminen) |
|  |
| Lokus | 3q26.1 | Alku | 165,772,904 bp |
| Loppu | 165,837,462 bp |

 |
|

| Geenisijainti (Hiiri) |
| --- |
|  |
| Kromosomi | Kromosomi 3 (hiiri) |
|  |
| Lokus | 3|3 E3 | Alku | 73,543,141 bp |
| Loppu | 73,615,748 bp |

 |
|

| RNA-ilmenemisen kaava |
| --- |
| Bgee |

| **Geenisijainti (Ihminen)** | **Geenisijainti (Hiiri)** |
| --- | --- |
|

|  |
| --- |
| Top expressed in |
| * parietal pleura
* right lobe of liver
* germinal epithelium
* left uterine tube
* muscle layer of sigmoid colon
* perikardium
* Rakkularauhanen
* visceral pleura
* ventricular zone
* body of uterus
 |

 |

|  |
| --- |
| Top expressed in |
| * pohjukaissuoli
* left lobe of liver
* nouseva aortta
* valkoinen rasvakudos
* atrium
* ruskea rasva
* intercostal muscle
* epithelium of stomach
* tyhjäsuoli
* lumbar spinal ganglion
 |

 |
| Lisää ilmenemistietoa |

 |
| BioGPS |

|  |
| --- |
|  |
| Lisää ilmenemistietoa |

 |

 |
|

| Geenin ontologia |
| --- |
| Molekulaarinen toiminto | * carboxylic ester hydrolase activity
* amyloid-beta binding
* cholinesterase activity
* choline binding
* Katalyyttinen aktiivisuus
* identical protein binding
* acetylcholinesterase activity
* enzyme binding
* hydrolaasiaktiivisuus
* hydrolase activity, acting on ester bonds
 |
| Solukomponentti | * endoplasmic reticulum lumen
* blood microparticle
* membrane
* extracellular region
* endoplasmakalvosto
* nuclear envelope lumen
* extracellular space
 |
| Biologinen prosessi | * choline metabolic process
* response to nutrient
* neuroblast differentiation
* response to glucocorticoid
* negative regulation of synaptic transmission
* oppiminen
* cocaine metabolic process
* response to alkaloid
* response to folic acid
* negative regulation of cell population proliferation
 |
| Lähteet:Amigo / QuickGO |

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|

| Ortologia |
| --- |
| Laji | **Ihminen** | **Hiiri** |
| Entrez |

|  |
| --- |
| 590 |

 |

|  |
| --- |
| 12038 |

 |
| Ensembl |

|  |
| --- |
| ENSG00000114200 |

 |

|  |
| --- |
| ENSMUSG00000027792 |

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| UniProt |

|  |
| --- |
| P06276 |

 |

|  |
| --- |
| Q03311 |

 |
| RefSeq (mRNA) |

|  |
| --- |
| NM\_000055 |

 |

|  |
| --- |
| NM\_009738 |

 |
| RefSeq (proteiini) |

|  |
| --- |
| NP\_000046 |

 |

|  |
| --- |
| NP\_033868 |

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| Lokaatio (UCSC) | Chr 3: 165.77 – 165.84 Mb | Chr 3: 73.54 – 73.62 Mb |
| PubMed haku |  |  |

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| Wikidata |
|

|  |  |
| --- | --- |
| Ihminen Wikidatassa | Hiiri Wikidatassa |

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**Pseudokoliiniesteraasi** eli **butyryylikoliiniesteraasi** on koliiniesteraaseihin kuuluvia entsyymi. Sitä esiintyy plasmassa ja syntetisoituu merkittävimmin maksassa.

## Lähteet

## Aiheesta muualla

* MeSH: Butyryylikoliiniesteraasi