# BCHE

| BCHE |
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|  |
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| Strwythurau |
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| PDB | Human UniProt search: PDBe RCSB  |
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| Rhestr o ddynodwyr PDB |
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| 1P0P, 4AXB, 4B0P, 2XQG, 1XLV, 2WIK, 2WIL, 1P0Q, 1XLU, 4BDS, 2XQF, 2PM8, 2XQK, 4AQD, 4BBZ, 2WID, 2XMB, 1XLW, 2XMC, 4TPK, 2XMG, 2XMD, 3DKK, 3O9M, 2WSL, 2WIJ, 1P0I, 2WIG, 2XQJ, 3DJY, 1P0M, 4B0O, 2XQI, 2Y1K, 4XII, 2WIF, 2J4C |

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| Dynodwyr |
| Cyfenwau | BCHE, CHE1, CHE2, E1, butyrylcholinesterase, BCHED |
| Dynodwyr allanol | OMIM: 177400 HomoloGene: 20065 GeneCards: BCHE  |
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| Patrwm RNA pattern |
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| Rhagor o gyfeiriadau  |

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| Ontoleg y genyn |
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| Gweithrediad moleciwlaidd | • GO:0004091 carboxylic ester hydrolase activity • amyloid-beta binding • cholinesterase activity • choline binding • catalytic activity • identical protein binding • acetylcholinesterase activity • enzyme binding • hydrolase activity • hydrolase activity, acting on ester bonds  |
| Cydrannau o'r gell | • endoplasmic reticulum lumen • blood microparticle • bilen • extracellular region • Reticwlwm endoplasmig • nuclear envelope lumen • extracellular space  |
| Prosesau biolegol | • choline metabolic process • response to nutrient • neuroblast differentiation • response to glucocorticoid • negative regulation of synaptic transmission • learning • proses metabolig cocên • response to alkaloid • response to folic acid • negative regulation of cell population proliferation  |
| Sources:Amigo / QuickGO |

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| Orthologau |
| Species | **Bod dynol** | **Llygoden** |
| Entrez |

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| --- |
| 590 |

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| n/a |

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| Ensembl |

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| --- |
| ENSG00000114200 |

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| --- |
| n/a |

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| UniProt |

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| P06276 |

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| --- |
| n/a |

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| RefSeq (mRNA) |

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| --- |
| NM\_000055 |

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| --- |
| n/a |

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| RefSeq (protein) |

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| --- |
| NP\_000046 |

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|  |
| --- |
| n/a |

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| Lleoliad (UCSC) | n/a | n/a |
| PubMed search |  | n/a |
| Wicidata |
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|  |  |
| --- | --- |
| Gweld/Golygu Bod dynol |  |

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Protein sy'n cael ei godio yn y corff dynol gan y genyn *BCHE* yw **BCHE** a elwir hefyd yn *Butyrylcholinesterase* (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 3, band 3q26.1.

## Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn BCHE.

* E1
* CHE1
* CHE2

## Llyfryddiaeth

* "*Human butyrylcholinesterase efficacy against nerve agent exposure.* ". *J Biochem Mol Toxicol*. 2017. PMID 28225154.
* "*Low Serum-Butyrylcholinesterase Activity as a Prognostic Marker of Mortality Associates with Poor Cardiac Function in Acute Myocardial Infarction.* ". *Clin Lab*. 2016. PMID 27468571.
* "*Activity and polymorphisms of butyrylcholinesterase in a Polish population.* ". *Chem Biol Interact*. 2016. PMID 27109752.
* "*Butyrylcholinesterase expression is regulated by fatty acids in HepG2 cells.* ". *Chem Biol Interact*. 2016. PMID 27106529.
* "*Understanding the non-catalytic behavior of human butyrylcholinesterase silent variants: Comparison of wild-type enzyme, catalytically active Ala328Cys mutant, and silent Ala328Asp variant.*". *Chem Biol Interact*. 2016. PMID 27062896.

## Cyfeiriadau