Virotherapy | Wikipedia audio article
Channel: wikipedia tts
Date: 06/05/2019

This is an audio version of the Wikipedia Article:
https://en.wikipedia.org/wiki/Virotherapy


00:01:11 1 Oncolytic virotherapy
00:03:17 2 Viral gene therapy
00:04:42 3 Viral immunotherapy
00:07:11 4 Specific projects and products
00:07:22 4.1 Oncolytic viruses
00:09:10 4.2 Viral gene therapy
00:09:30 4.3 Protozoal virotherapy
00:11:29 5 History
00:11:50 6 See also



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SUMMARY
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Virotherapy is a treatment using biotechnology to convert viruses into therapeutic agents by reprogramming viruses to treat diseases. There are three main branches of virotherapy: anti-cancer oncolytic viruses, viral vectors for gene therapy and viral immunotherapy. These branches utilize three different types of treatment methods: gene overexpression, gene knockout, and suicide gene delivery. Gene overexpression adds genetic sequences that compensate for low to zero levels of needed gene expression. Gene knockout utilizes RNA methods to silence or reduce expression of disease-causing genes. Suicide gene delivery introduces genetic sequences that induce an apoptotic response in cells, usually to kill cancerous growths. In a slightly different context, virotherapy can also refer more broadly to the use of viruses to treat certain medical conditions by killing pathogens.