Crosstalk Between Triple Negative Breast Cancer and Microenvironment | Oncotarget
Channel: Oncotarget
Date: 2023-04-10

Oncotarget published this review on March 31, 2023 in Volume 14, entitled, “Crosstalk between triple negative breast cancer and microenvironment" by researchers from Department of Pharmaceutical Sciences, Albany College of Pharmacy and Health Science, Albany, NY.
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DOI - https://doi.org/10.18632/oncotarget.28397

Correspondence to - Kideok Jin - kideok.jin@acphs.edu

Abstract

Although many advances have been made in the treatment of breast cancer, for the triple negative breast cancer (TNBC) these therapies have not significantly increased overall survival. Tumor microenvironment (TME) plays an essential role to develop and control TNBC progression. Many preclinical and clinical studies are ongoing to treat patients with TNBC disease, but the effective therapies are currently not available. Here, we have reviewed recent progress in understanding of TNBC and advance in defining mechanisms of TNBC therapies and potential therapeutic strategies to overcome TNBC.

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Keywords - triple negative breast cancer, tumor microenvironment, current therapy

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