Heather Harrington's talk at the 2021 annual meeting of the UK centre for Topological Data Analysis
Channel: 2021 annual meeting of the centre for TDA
Date: 2021-09-20

Title. Algebraic systems biology: topology links models and biological data.
Abstract. Signalling pathways in molecular biology can be modelled by polynomial dynamical systems. I will present models describing biological systems involved in development and cancer. I will overview approaches to analyse these models with data using computational geometry, topology, statistics and dynamics. These methods can provide new insights to better understand model parameter values and biological insights, such as how changes at the molecular scale (e.g. molecular mutations) result in kinetic differences and observed phenotypic changes (e.g. mutations in fruit fly wings).