Iron Deficiency Anemia: Everything you need to know *ANIMATED* (with Lecture Notes)
Channel: MedicoVisual - Visual Medical Lectures
Date: 2019-06-24

Free Printable PDF Lecture notes: https://bit.ly/31KMjKx

Like our Facebook Page: https://www.facebook.com/MedicoVisual/

Sound effects and music obtained from www.zapsplat.com

In this lecture we will discuss:

Pluripotent hematopoietic Stem Cell
Basic concept of Erythropoiesis 
Structure of Hemoglobin
Incorporation of Iron in Protoporphyrin ring
Toxic effects of free protoporphyrin ring
How Microcytic Hypochromic RBCs are formed?
How Cigar cells / Pencil cells / Elliptical Cells are formed?
Sources of Iron
Iron Absorption from the diet
Structure of Ferritin
Iron Metabolism
Rationale of Serum Ferritin levels
Role of hepcidin
Transferrin
How liver prevents Iron Overload
Physiological losses of Iron
Iron absorption analogy / visual mnemonic
Recycling of Iron from old RBCs
Structure of splenic sinusoids
Role of splenic macrophages
What is hemosiderin
Pathological losses of Iron
Etiology of Iron deficiency Anemia / Causes of Iron deficiency Anemia
Iron Pool
Iron deficiency in chronic blood loss
Clinical features of Iron deficiency anemia
Molecular and Biochemical basis of development of Erythroid clinical features of iron deficiency anemia
Oxidative Phosphorylation in iron deficiency
Pallor
Role of iron in cellular proliferation
What is ribonucleotide reductase
How atrophic glossitis develops
Role of gastric acid in iron absorption
How koilonychia develops
Pathogenies /Pathophysiology of Koilonychia
Spoon shaped nails
Role of Iron in cystine metabolism
Cystathione Beta Synthase
Role of Iron in neurotransmitter synthesis (Serotonin, Dopamine)
Psychological and Behavioral manifestations of Iron deficiency anemia
Pica and it’s pathogenesis
Restless leg syndrome
Summary of clinical features of Iron deficiency anemia
Investigations of Iron deficiency anemia
Concept of packed cell volume and hematocrit
Why life span of RBCs is reduced in Iron deficiency anemia
Concept of RDW (Red Cell Distribution Width)
What is Anisocytosis
What Poikilocytosis
Why platelet count is increased in iron deficiency anemia
Free Protoporphyrin levels / Zinc Protoporphyrin levels
Iron Studies
Review of Iron deficiency anemia
Case scenarios 

Website: https://www.medicovisual.com
Email: draizaz@medicovisual.com