History of molecular biology | Wikipedia audio article
Channel: wikipedia tts
Date: 2018-12-25

This is an audio version of the Wikipedia Article:
https://en.wikipedia.org/wiki/History_of_molecular_biology


00:01:10 1 General overview
00:04:06 2 The exploration of the molecular dominion
00:05:57 3 The encounter between biochemistry and genetics
00:09:52 4 History of DNA biochemistry
00:10:08 4.1 First isolation of DNA
00:11:45 4.2 Chromosomes and inherited traits
00:13:41 4.3 Discovery of the structure of DNA
00:14:42 4.4 Helix structure
00:15:37 4.5 Complementary nucleotides
00:18:09 4.6 "Central Dogma"
00:19:14 5 History of RNA tertiary structure
00:19:25 5.1 Pre-history: the helical structure of RNA
00:21:37 5.2 The beginning: crystal structure of tRNAsupPHE/sup
00:24:31 5.3 The renaissance: the hammerhead ribozyme and the group I intron: Psub4-6/sub
00:28:32 5.4 The modern era: the age of RNA structural biology
00:29:42 6 History of protein biochemistry
00:29:52 6.1 First isolation and classification
00:31:50 6.2 Purifications and measurements of mass
00:34:11 6.3 Protein folding and first structural models
00:34:29 7 See also
00:38:37 8 References



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SUMMARY
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The history of molecular biology begins in the 1930s with the convergence of various, previously distinct biological and physical disciplines: biochemistry, genetics, microbiology, virology and physics.  With the hope of understanding life at its most fundamental level, numerous physicists and chemists also took an interest in what would become molecular biology.
In its modern sense, molecular biology attempts to explain the phenomena of life starting from the macromolecular properties that generate them.  Two categories of macromolecules in particular are the focus of the molecular biologist: 1) nucleic acids, among which the most famous is deoxyribonucleic acid (or DNA), the constituent of genes, and 2) proteins, which are the active agents of living organisms. One definition of the scope of molecular biology therefore is to characterize the structure, function and relationships between these two types of macromolecules. This relatively limited definition will suffice to allow us to establish a date for the so-called "molecular revolution", or at least to establish a chronology of its most fundamental developments.