GReTA seminar #25: "Rule-based Models of Epidemics"
Channel: GReTA Seminar
Date: 2022-01-28

Speaker:

William Waites (University of Strathclyde, Scotland, UK)


Abstract:

Rule-based models, a particular kind of graph rewriting system initially intended for use in molecular biology, are conspicuously useful for understanding epidemics. They enable formulation of complex processes that blends the ease of understanding of "compartmental" models with the expressiveness of individual- or agent-based models. We illustrate this with a story, told in graph rewriting rules, of how the adaptive immune response to a pathogen works (simplified version) and how this response influences the population level dynamics of an epidemic. This model can be calibrated against real-world data and we see how some of the individual heterogeneity that is normally treated phenomenologically in the study of epidemics arises naturally from this account of immune response.


About the GReTA seminars:

The GReTA – Graph TRansformation Theory and Applications virtual seminar series aims to serve as a platform for the international graph rewriting community, to promote recent developments and trends in the field, and to permit a regular networking and interaction between members of this community. Seminars are held twice a month in the form of Zoom sessions (some of which will be live-streamed to YouTube). Please refer to http://www.irif.fr/~greta for further details (including information on how to register for participating in the Zoom meetings).