Selfotel | Wikipedia audio article
Channel: wikipedia tts
Date: 2018-10-27

This is an audio version of the Wikipedia Article:
Selfotel

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This video uses Google TTS en-US-Standard-D voice.



SUMMARY
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Selfotel (CGS-19755) is a drug which acts as a competitive NMDA antagonist, directly competing with glutamate for binding to the receptor. Initial studies showed it to have anticonvulsant, anxiolytic, analgesic and neuroprotective effects, and it was originally researched for the treatment of stroke, but subsequent animal and human studies showed phencyclidine-like effects, as well as limited efficacy and evidence for possible neurotoxicity under some conditions, and so clinical development was ultimately discontinued.