Collagen | Wikipedia audio article
Channel: wikipedia tts
Date: 2019-10-02

This is an audio version of the Wikipedia Article:
https://en.wikipedia.org/wiki/Collagen


00:01:26 1 Types
00:02:55 2 Medical uses
00:03:04 2.1 Cardiac applications
00:04:43 2.2 Cosmetic surgery
00:05:42 2.3 Bone grafts
00:06:22 2.4 Tissue regeneration
00:06:57 2.5 Reconstructive surgical uses
00:07:28 2.6 Wound care
00:09:07 3 As a supplement
00:09:58 4 Basic research
00:10:16 5 Veterinary use
00:10:37 6 Chemistry
00:11:22 7 Synthesis
00:16:10 7.1 Amino acids
00:17:06 7.2 Collagen I formation
00:18:52 7.3 Synthetic pathogenesis
00:19:44 8 Molecular structure
00:26:18 9 Associated disorders
00:26:49 10 Diseases
00:28:30 11 Characteristics
00:29:33 11.1 Uses
00:31:39 12 History
00:33:42 13 D-banding



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SUMMARY
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Collagen  is the main structural protein in the extracellular space in the various connective tissues in the body. As the main component of connective tissue, it is the most abundant protein in mammals, making 25% to 35% of the whole-body protein content. Collagen consists of amino acids bound together to form triple-helices of elongated fibrils. It is mostly found in fibrous tissues such as tendons, ligaments, and skin.
Depending upon the degree of mineralization, collagen tissues may be rigid (bone), compliant (tendon), or have a gradient from rigid to compliant (cartilage). It is also abundant in corneas, blood vessels, the gut, intervertebral discs, and the dentin in teeth. In muscle tissue, it serves as a major component of the endomysium. Collagen constitutes one to two percent of muscle tissue and accounts for 6% of the weight of strong, tendinous, muscles. The fibroblast is the most common cell that creates collagen. Gelatin, which is used in food and industry, is collagen that has been irreversibly hydrolyzed. Collagen has many medical uses in treating complications of the bones and skin.
The name collagen comes from the Greek κόλλα (kólla), meaning "glue", and suffix -γέν, -gen, denoting "producing". This refers to the compound's early use in the process of boiling the skin and tendons of horses and other animals to obtain glue.