genetic testing for pain and neurofibromatosis
Channel: positive affirmations with ketina
Date: 2020-02-28

quadriplegic talks about how gain range of motion and genetic testing

Genetic testing can be used to explore the genes that encode the enzymes that metabolize opioid and nonopioid medications, the transporters, the receptors, and even the more cerebral aspects of perceiving and processing pain

Many common pain medications require activation by an enzyme called CYP2D6 to become effective. Approximately half of all patients have genes that alter the function of CYP2D6. Other metabolic pathways include CYP2B6, CYP2C9, CYP2C19, CYP3A4, CYP3A5, COMT, and OPRM1 [17]. Testing for these gene alterations allows for dosage modifications to compensate for genetic differences and optimize the safety and efficacy of the opioid family of analgesics.

Genetic testing is also used to diagnose NF1 and NF2. Testing conducted before birth (prenatal) is helpful to identify individuals who have a family history of the disorder, but do not yet have the symptoms.Aug 16, 2016