SUPPOSITORY BASE, PART-3, GLYCERO-GELATIN BASE, SYNTHETIC FATS USE IN THE PREPARATION OF SUPPOSITORY
Channel: PHARMAROCKS THE WAY OF SUCCESS
Date: 2021-03-27

SUPPOSITORIES, 
Suppositories are semi-solid dosage forms intended for insertion into body orifices 
Like rectum, vagina, urethra where they melt, soften, or dissolve at body temperature and provide a local or systemic effect to treat various diseases.

WHAT IS SUPPOSITORIES BASE?
Suppository base excipients are used in the manufacture of suppositories.
They can be hydrophobic or hydrophilic. 
Suppositories should melt at just below body temperature 37°C
which allows for erosion of the dosage form and release of the API. 
Hard fat suppository bases melt at approximately body temperature.

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