Promoter (biology) | Wikipedia audio article
Channel: wikipedia tts
Date: 2018-12-27

This is an audio version of the Wikipedia Article:
https://en.wikipedia.org/wiki/Promoter_(genetics)


00:00:28 1 Overview
00:02:17 2 Identification of relative location
00:02:55 3 Relative location in the cell nucleus
00:03:29 4 Elements
00:03:38 4.1 Eukaryotic
00:05:27 4.2 Bacterial
00:07:21 4.2.1 Probability of occurrence of each nucleotide
00:08:34 4.3 Eukaryotic
00:09:16 4.3.1 Bidirectional (mammalian)
00:11:15 5 Subgenomic
00:14:13 6 Detection
00:15:06 7 Evolutionary change
00:15:52 7.1 De novo origin of promoters
00:16:29 8 Diabetes
00:17:08 9 Binding
00:17:49 9.1 Location
00:18:36 10 Diseases associated with aberrant function
00:19:10 11 CpG islands in promoters
00:20:23 12 Methylation of CpG islands stably silences genes
00:21:42 13 Promoter CpG hyper/hypo-methylation in cancer
00:22:32 14 Canonical sequences and wild-type
00:23:57 15 Diseases that may be associated with variations
00:25:15 16 Constitutive vs regulated
00:25:47 17 Use of the term
00:26:12 18 See also



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SUMMARY
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In genetics, a promoter is a region of DNA that initiates transcription of a particular gene. Promoters are located near the transcription start sites of genes, on the same strand and upstream on the DNA (towards the 3' region of the anti-sense strand).
Promoters can be about 100–1000 base pairs long.