IU X-Informatics Unit 27: Health 6: Genomics, Proteomics and Information Visualization I
Channel: Digital Science Center Courses
Date: 2013-09-11

Lesson Overview:
A study of an Azure application with an Excel frontend and a cloud BLAST backend starts this lesson. This is followed by a big data analysis of personal genomics and an analysis of a typical DNA sequencing analytics pipeline. The Protein Sequence Universe is defined and used to motivate Multi dimensional Scaling MDS. Sammon's method is defined and its use illustrated by a metagenomics example. Subtleties in use of MDS include a monotonic mapping of the dissimilarity function. The application to the COG Proteomics dataset is discussed. We note that the MDS approach is related to the well known chisq method and some aspects of nonlinear minimization of chisq (Least Squares) are discussed.

Enroll in this course at https://bigdatacourse.appspot.com/ and download course material, see information on badges and more. It's all free and only takes you a few seconds.