7 Lorrca osmoscan sample preparation
Channel: Jan de Zoeten RRM
Date: 2015-05-10

The osmoscan measures the deformability under an osmotic gradient.

Measurement
The Lorrca® has the ability to automatically measure RBC deformability over a gradient of osmotic values. This results in a continuous curve which shows the cell’s condition at the different osmotic values. The osmoscan provides information about the cell’s deformability and membrane rigidity, depending on both the shape and the position along the osmolality axis. For this test 200 μl of whole blood is needed.

Lorrca Maxsis osmoscan is a unique instrument which combines Red Blood Cell (RBC) deformability by ektacytometry, osmoscan and aggregometry; all temperature controlled. It is capable of fully automated measurement and calculation of various phenomena of RBC’s by analysis of their rheological behavior. The technique accurately detects deformability as a function of shear stress, pre-hemolytic stability and aggregation of the RBC’s and is of added value for hematology analysis.