Genetics of Cerebral Palsy | Dr Clare van Eyk
Channel: verbalize science
Date: 2018-07-02

Full audio:
http://verbalize.science/talk_page/genetics-of-cerebral-palsy-1528721526398x113986879601508350

The cellular mechanisms underlying cerebral palsy are not well understood. In this study, we used RNA sequencing to measure the gene messengers (RNA) in cells from children with cerebral palsy. Cell lines from 182 individuals with cerebral palsy were studied and many showed disruption of cell signalling and inflammatory pathways, as seen in some children with autism. The results showed that the neurological or signalling pathways being disrupted in children with cerebral palsy overlap with those disruptions seen in autism. Together, these results have highlighted some common processes which are disrupted in cells in individuals with cerebral palsy.

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