SIB Days 2020: Mathematical and computational approaches to solve biological problems
Channel: SIB - Swiss Institute of Bioinformatics
Date: 2020-07-01

Parallel Session 8: Computational Approaches

The quantity of data generated by the life sciences has grown exponentially over the years, the best way to handle and analyse the massive data generated is still a major challenge. It is also necessary to explore them with a systemic approach to reveal the behaviour of the system as a whole rather than as the sum of its part. Hence, this session of SIB Days 2020 brings together researchers to discuss statistical and algorithmic approaches to improve data management, analysis, and interpretation.

Session Chairs: Luciano Cascione (Bioinformatics Core Unit, Institute of Oncology Research), Franziska Singer (Clinical Bioinformatics Unit, ETH Zurich) 

Talks (click to access specific sections of the talk)
Session introduction 00:00
Preprocessing choices affect RNA velocity results for droplet scRNA-seq data, Charlotte Soneson, FMI Computational Biology Group, Friedrich Miescher Institute, Basel 01:01
Towards creating a new knowledge base for literature-based discovery, Anna Koroleva, Applied Computational Genomics Team, Zurich University of Applied Sciences (ZHAW), Wädenswil 06:35
HOTs Hierarchical Orthologous Transcripts, Yannis Nevers, Laboratory of Computational Evolutionary Biology, University of Lausanne 12:22
A machine learning approach on "signalomics" data to improve decision making at the ICU, Elena Montegro Borbolla, Computational Intelligence for Computational Biology (CI4CB), HEIG-VD, Yverdon-Les-Bains 18:18
Coarse-graining of single-cell RNA-seq data preserves clustering and improves detection of gene correlations, Mariia Bilous, Computational Cancer Biology Group, University of Lausanne 23:36
Fast Efficient Accurate Entity Recognition for biomedical applications, Fabio Rinaldi, BioMeXT: Biomedical Information Extraction, University of Zurich 29:16
A novel approach to detect the influence of RNA-binding proteins on pre-mRNA processing, Maciej Bak, RNA Regulatory Networks Group, University of Basel 41:35

About the SIB Days: this internal conference of the SIB Swiss Institute of Bioinformatics is organized every two years. Its ambition? To give a voice to SIB's 80 Groups across Switzerland, through a diversity of bioinformatics topics, and to offer its 800 SIB Members an opportunity to meet and learn about each other’s research and activities in a friendly atmosphere. Due to this year’s events, the conference has taken place virtually for the first time, on 8-10 June 2020. Most of the talks could be made public post-event.


Read more about the SIB Days: https://www.sib.swiss/about-sib/news/10713-virtual-sib-days-2020-swiss-bioinformatics-highlights-recorded-sessions