PHI-Canto: Annotating an inverse gene-for-gene interaction
Channel: PHI-base
Date: 2023-04-12

This tutorial demonstrates how to annotate an inverse gene-for-gene interaction between a pathogen and a host using PHI-Canto. The tutorial also includes instructions on creating related annotations, such as Gene Ontology (GO) annotations, Pathogen-host interaction phenotype annotations, and Disease name annotations.

00:00 Introduction
00:30 GO biological process annotation
01:46 GO molecular function annotation
03:44 Inverse gene-for-gene phenotypes (control)
07:24 Interaction with transformed host gene
09:42 Interaction with mutated host gene
12:43 Protein-protein interaction phenotype
16:27 Disease name annotation

PHI-Canto is an online annotation tool used for curation of peer-reviewed literature on pathogen-host interactions.

The tool is free to use, and can be used by any researcher who wants to curate a publication into PHI-base, the Pathogen-Host Interactions Database (http://www.phi-base.org).

If you want to curate a publication to be included in PHI-base, use the following link:
https://canto.phi-base.org

If you want to try using PHI-Canto without submitting data to PHI-base, we have a demo version of the tool available:
https://demo-canto.phi-base.org

PHI-Canto was developed by the PHI-base team at Rothamsted Research, in collaboration with the PomBase team at the University of Cambridge. PomBase are the creators of Canto, the annotation tool that PHI-Canto was derived from.