Dmitry Shvarev | Multiple roles of tripartite transporters in cyanobacteria
Channel: CyanoWorld
Date: 2021-05-23

Dmitry Shvarev - University of Osnabrück, Germany

Twitter: https://twitter.com/dmitryshvarev
Research Gate: https://www.researchgate.net/profile/Dmitry-Shvarev

Multiple roles of tripartite transporters in cyanobacteria

Due to their sophisticated lifestyle, cyanobacteria possess a relatively large genome that encodes various proteins, including many membrane transporters. Some of them form large tripartite complexes that build a tunnel, which spans the whole Gram-negative cell envelope from the inner membrane through the periplasm and the peptidoglycan layer to the outer membrane. Usually, they are composed of three types of proteins: the inner membrane transporter protein, the periplasmic membrane fusion protein, and the outer membrane protein. Such transport machines are considered of particular scientific interest since they transfer a variety of substances out of the cell and are important for a plethora of cellular processes. Recently, several studies have discovered the functions of a number of different tripartite transporters in unicellular and filamentous cyanobacteria. These transporters have been shown to play a role in antibiotic resistance, cell envelope formation, and other processes that are essential for cyanobacterial physiology. In this talk, I will give an overview of some tripartite transport systems in cyanobacteria and also discuss the functions of several novel ATP binding cassette (ABC) transporter-driven tripartite complexes that I studied during my Ph.D. project.

This talk is part of the CyanoWorld online seminar series, hosted by Nicolas Schmelling and Ilka Axmann, and was held on Zoom on May 13th, 2021.

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