Efflux (microbiology) | Wikipedia audio article
Channel: wikipedia tts
Date: 2019-03-27

This is an audio version of the Wikipedia Article:
https://en.wikipedia.org/wiki/Efflux_(microbiology)


00:00:47 1 Bacteria
00:00:57 1.1 Bacterial efflux pumps
00:02:47 1.2 Function
00:04:56 1.3 Impact on antimicrobial resistance
00:06:23 2 Eukaryotes
00:07:26 3 Efflux inhibitors
00:08:36 4 See also



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SUMMARY
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Active efflux is a mechanism responsible for moving compounds, like neurotransmitters, toxic substances, and antibiotics, out of cells; a process considered to be a vital part of xenobiotic metabolism. This mechanism is important in medicine as it can contribute to bacterial antibiotic resistance.
Efflux systems function via an energy-dependent mechanism (active transport) to pump out unwanted toxic substances through specific efflux pumps. Some efflux systems are drug-specific, whereas others may accommodate multiple drugs with small multidrug resistance (SMR) transporters.