Pathophysiology of HIV/AIDS | Wikipedia audio article
Channel: wikipedia tts
Date: 2019-03-27

This is an audio version of the Wikipedia Article:
https://en.wikipedia.org/wiki/Pathophysiology_of_HIV/AIDS


00:00:43 1 Immunology
00:04:44 2 CD4 T-cell Death and Inflammation
00:06:25 3 Cells affected
00:07:09 4 The effect
00:08:15 5 Molecular basis



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SUMMARY
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HIV is commonly transmitted via unprotected sexual activity, blood transfusions, hypodermic needles, and from mother to child. Upon acquisition of the virus, the virus replicates inside and kills T helper cells, which are required for almost all adaptive immune responses. There is an initial period of influenza-like illness, and then a latent, asymptomatic phase. When the CD4 lymphocyte count falls below 200 cells/ml of blood, the HIV host has progressed to AIDS, a condition characterized by deficiency in cell-mediated immunity and the resulting increased susceptibility to opportunistic infections and certain forms of cancer.