Presentations - pathogenic variants, FOXO3, protein folding, DNA art - Bioinformatics Hackathon 2020
Channel: BioHackathon-dk
Date: 2020-07-27

BioHackthon 2020 - Presentation of results by participants, part 2.

Presentations of results from teams, who were solving the following challenges (also known as Venue Midgard):
- Classifying pathogenic and benign protein variants by Amelie Stein, University of Copenhagen,
- Are FOXO3 genetic variants associated with cardiovascular diseases by Victor Bustos, Apollo Ventures,
- Protein origami: 3D folding with deep learning by Jeppe Hallgren, BioLib,
- Art from your DNA by Lasse Folkersen, Sankt Hans Hospital.

Use the time-codes for navigation:
00:00 - Start, nothing happening,

- Classifying pathogenic and benign protein variants:
00:36 - Team BnB, Classifying the variants,
05:49 - Team MetaHack, Exploratory analysis of data and performance of different models,
11:25 - Team Trekkers, Imputation of missing values and curious cases of colon cancer and BRCA2,
17:08 - Team Modern-Synthesis, Neural-network based classification

-  Are FOXO3 genetic variants associated with cardiovascular diseases:
23:32 - Team VarFinders, Analysis and heatmap visualization of FOXO3 CVD-related genetic associations,
30:18 - Team Nocturnal Animals, Analysis and interactive visualization of FOXO family genetic associations,
35:53 - Team How-I-met-my-genome, Analysis and 3D VR visualization of GWAS data,

- Protein origami: 3D folding with deep learning:
41:13 - Team Biologicians, Using convolutional neural networks (CNN) for protein folding,
47:02 - Team if_ubiquitin_break, Improving the loss function for protein folding,
53:05 - Total chaos by the host 😅
54:15 - Team Protheans, Using skip-grams and word2vec,

- Art from your DNA:
57:28 - Team Genswer, Creating a coat of arms and poem using generative adversarial networks (GANs),
1:02:48 - Team 2-master-students, DNA 2D game maps,
1:07:47 - Team [Placeholder], Abstract art for phone screen using GANs,
1:12:30 - Team Genome Gnomes, DeepDream pixelated generative art,
1:17:27 - Team deep-DNArt, Personal karyospectrum using GANs,
1:23:06 - Team Geneage Mutation Ninja Tuxes, Biopolitical Donald Fake Trump tweets.

The submissions are available at https://biolib.com/explore/BioHackathon2020

This video is a part of a 48-hour long online bioinformatics hackathon, that took place in April 2020. 175 students, developers, and data scientists from more than 20 countries have participated in the hackathon to solve one of the eight challenges provided by mentors from industry, startups, venture funds, and academia. The event was organized by CBioVikings (https://www.facebook.com/CBIOVikingsDK, Danish team of International Society for Computational Biology) and BioLib (https://biolib.com/).