CH450 Chapter 8.3 and 8.4 Allosteric Enzymes and Zymogens
Channel: Patricia Flatt
Date: 2020-11-04

In this lecture we define the nature of allosteric enzyme regulation and the use of proenzymes (or zymogens) to control enzyme activity. Trypsinogen and Trypsin packaging in the pancreas are used as the major example of zymogen activation. The protease cascade within the duodenum of the small intestine is presented and includes endopeptidase, carboxypeptidase, chymotrypsin, elastase and lipase.