History of genetic engineering | Wikipedia audio article
Channel: wikipedia tts
Date: 2019-07-06

This is an audio version of the Wikipedia Article:
https://en.wikipedia.org/wiki/History_of_genetic_engineering


00:01:52 1 Agriculture
00:06:20 2 Genetics
00:10:17 3 Early genetically modified organisms
00:13:25 4 Regulation
00:15:49 5 Research and medicine
00:18:18 6 Further advances
00:22:06 7 Commercialisation
00:27:02 8 Opposition



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SUMMARY
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Genetic engineering as the direct transfer of DNA from one organism to another was first accomplished by Herbert Boyer and Stanley Cohen in 1964. It was the result of a series of advancements in techniques that allowed the direct modification of the genome. Important advances included the discovery of restriction enzymes and DNA ligases, the ability to design plasmids and technologies like polymerase chain reaction and sequencing. Transformation of the DNA into a host organism was accomplished with the invention of biolistics, Agrobacterium-mediated recombination and microinjection.
The first genetically modified animal was a mouse created in 1974 by Rudolf Jaenisch. In 1976 the technology was commercialised, with the advent of genetically modified bacteria that produced somatostatin, followed by insulin in 1978. In 1983 an antibiotic resistant gene was inserted into tobacco, leading to the first genetically engineered plant. Advances followed that allowed scientists to manipulate and add genes to a variety of different organisms and induce a range of different effects. Plants were first commercialized with virus resistant tobacco released in China in 1992. The first genetically modified food was the Flavr Savr tomato marketed in 1994. By 2010, 29 countries had planted commercialized biotech crops. In 2000 a paper published in Science introduced golden rice, the first food developed with increased nutrient value.