#4-02 - Centenarians, Biological Clocks, and Reversing Ageing
Channel: Max Planck PhDnet
Date: 2023-04-07

Today, Bea talks to Dr. Joris Deelen again after one year, about his research progress in the field of ageing and whether we are closer to understanding why some people age more healthily than others.  

Dr. Joris Deelen is a group leader at the Max Planck Institute for Biology of ageing. The research in his group focuses on studying the genetic mechanisms underlying healthy ageing in humans where they specifically look at the effect of genetic variants that are unique to long-lived individuals. Moreover, his group is trying to identify biomarkers of health ageing. 

Joris talks about the main differences between centenarians and others as well as certain longevity genes such as APOE2. He also explains how big the influence of the environment could be when you have the longevity gene. Bea and Joris talk about lifestyle factors and how we could adjust our lifestyle at different ages. Furthermore, they talk about yamanaka factors and the possibility of reversing ageing.

To find out more information about Dr. Deelen’s lab, check out here:
https://www.age.mpg.de/science/research-laboratories/deelen
https://www.cecad.uni-koeln.de/research/principal-investigators/dr-joris-deelen/

Joris’s Twitter: @Joris_Deelen

Episode Art: Photo by Sangharsh Lohakare on Unsplash 

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Intro - Outro music composed by Srinath Ramkumar: https://twitter.com/srinathramkumar
Pre-Intro jingle composed by Gustavo Carrizo: https://www.instagram.com/carrizo.gus

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