History of cancer chemotherapy | Wikipedia audio article
Channel: wikipedia tts
Date: 2019-03-26

This is an audio version of the Wikipedia Article:
https://en.wikipedia.org/wiki/History_of_cancer_chemotherapy


00:00:22 1 Beginnings
00:03:27 2 Antifolates
00:06:42 3 6-MP, vinca alkaloids
00:08:05 4 National Cancer Chemotherapy Service Center
00:09:02 5 Combination chemotherapy
00:11:12 6 Adjuvant therapy
00:12:43 7 Drug discovery at the NCI and elsewhere
00:12:56 7.1 Zubrod's initiatives
00:14:03 7.2 Taxanes
00:15:09 7.3 Camptothecins
00:16:14 7.4 Platinum-based agents
00:17:50 7.5 Nitrosoureas
00:18:25 7.6 Anthracyclines and epipodophyllotoxins
00:18:57 8 Supportive care during chemotherapy
00:20:39 9 Bone marrow transplantation
00:22:00 10 Antihormone therapy
00:22:25 11 Targeted therapy
00:23:00 11.1 Tyrosine kinase inhibitors
00:24:37 11.2 Monoclonal antibodies
00:25:37 12 Effectiveness
00:27:22 13 See also



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SUMMARY
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The era of cancer chemotherapy began in the 1940s with the first use of nitrogen mustards and folic acid antagonist drugs. The targeted therapy revolution had arrived, but many of the principles and limitations of chemotherapy discovered by the early researchers still apply.