Nitrous acid `(HNO_(2))` converts amino acids into hydroxy acids with retention of configuration.
Channel: Doubtnut
Date: 2020-01-26

Nitrous acid `(HNO_(2))` converts amino acids into hydroxy acids with retention of configuration. Estimation of nitrogen gas evolved in the reaction is the basis of Van slyke estimation of amino acids. `R-overset(overset(NH_(2))(|))(CH)-COOH overset(HNO_(2))rarr R- overset(overset(OH)(|))(CH)-COOH + N_(2) uarr +H_(2)O` Which of the following amino acids cannot be analysed by Van slyke method ? (I) `HS-CH_(2)-overset(overset(NH_(2))(|))(CH)-COOH` (cysteine)