Reduced muscle mass, strength and performance in space | Wikipedia audio article
Channel: wikipedia tts
Date: 2019-03-27

This is an audio version of the Wikipedia Article:
https://en.wikipedia.org/wiki/Reduced_muscle_mass,_strength_and_performance_in_space


00:00:40 1 Introduction
00:08:44 2 Historical overview
00:08:54 2.1 U.S. human spaceflight programs
00:09:02 2.1.1 Mercury and Gemini
00:14:04 2.1.2 Apollo
00:23:01 2.1.3 Skylab
00:34:05 2.1.4 Space Shuttle
00:47:39 2.1.5 Shuttle-Mir and NASA-Mir
00:49:58 2.1.6 International Space Station (ISS)
00:56:39 2.2 Other human spaceflight
01:08:51 2.3 Ground-based analog studies
01:28:01 2.4 Experimental animal studies
01:32:04 2.4.1 Activity patterns during spaceflight
01:34:07 2.4.2 Activity patterns in early recovery from spaceflight
01:35:28 2.4.3 Effects of spaceflight and hindlimb suspension on muscle mass, protein content and gross morphological properties of skeletal muscle
01:39:27 2.4.4 Muscle fiber phenotype remodeling in response to spaceflight and hind-limb suspension
01:42:49 2.4.5 Metabolic processes
01:44:50 2.4.6 Functional correlates to the alterations in muscle mass and contractile phenotype in response to spaceflight
01:48:41 2.4.7 Are atrophied muscles vulnerable to injury
01:51:36 2.4.8 Cellular and molecular mechanisms of muscle atrophy in response to unloading stimuli
01:56:15 2.4.9 Effects of spaceflight on non-human primates
01:59:43 3 Computer-based simulation information
02:01:14 4 Future exploration missions
02:05:34 4.1 Lunar sortie missions
02:09:50 4.2 Lunar outpost missions
02:11:03 4.3 Mars transit
02:12:33 4.4 Mars outpost
02:13:52 5 Current gaps
02:14:47 5.1 In microgravity
02:17:54 5.2 In analog environments
02:19:02 5.3 Exploration mission operational scenarios
02:20:03 6 See also



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SUMMARY
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There is a growing research database which suggests that skeletal muscles, particularly postural muscles of the lower limb, undergo atrophy and structural and metabolic alterations during space flight.  However, the relationships between in-flight exercise, muscle changes and performance are not well understood. Efforts should be made to try to understand the current status of in-flight and post-flight exercise performance capacity and what the goals/target areas for protection are with the current in flight exercise program.