Amides with no substitution on nitrogen react with tht: solution of bromine or chlorine in N
Channel: Doubtnut
Date: 2020-04-05

Amides with no substitution on nitrogen react with tht: solution of bromine or chlorine in NaOH or KOH to yield aminei through a reaction called as Hofmann\'s degradation. `R-overset(O)overset(||)(C )-NH_(2)+Br_(2)+4NaOH overset(H_(2)O)rarr R-NH_(2)+2NaBr+Na_(2)CO_(3)+2H_(2)O` Amides can be reduced to amines having same number of carbon atoms `R-overset(O)overset(||)C-NH_(2)-underset(LiAlH_(4))overset([H])toR-CH_(2)-NH_(2)` Iso-cyanates are formed as intermediate in the Hofmann\'s degradation..