Thymus |Lymphoid structures | Immunology | First Aid Lectures | Lec.3 #drjamillectures
Channel: Dr. Jamil Lectures
Date: 2022-03-22

In this lecture we will discuss about Thymus anatomy,its structure,its function,Hassal corpuscles,Thymoma 

https://youtu.be/gXGK6F_vDJQ
https://youtu.be/U3aD-wn2zMM
https://youtu.be/aP06bUvyqCA
Instagram Account   dr_jamil56

Thymus
It is located in the anterosuperior mediastinum behind the sternum. 
It is the site of T-cell differentiation and maturation. 
It is encapsulated. Thymus epithelium is 
derived from Third pharyngeal pouch 
(endoderm), whereas thymic lymphocytes 
are derived from mesoderm.Its Cortex is dense 
with immature T cells whereas Medulla is pale with 
Mature T cells and Hassall corpuscles (containing epithelial reticular cells)
Normal neonatal thymus “sail-shaped” on 
X-Ray but involutes by age 3 years.
Absent thymic shadow or hypoplastic thymus 
seen in some immunodeficiencies (eg, SCID, 
DiGeorge syndrome).
Thymoma
cancer of thymus and it is associated 
with myasthenia gravis, superior vena cava 
syndrome, pure red cell aplasia, Good 
syndrome.

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