Clostridium perfringens | Wikipedia audio article
Channel: wikipedia tts
Date: 2018-12-07

This is an audio version of the Wikipedia Article:
Clostridium perfringens


00:01:34 1 Genome
00:02:24 2 Motility
00:03:26 3 Food poisoning
00:06:08 4 Infection
00:06:48 5 Treatment
00:07:23 6 Diagnosis
00:08:43 7 Prevention
00:09:37 8 Food poisoning incidents
00:12:46 9 Epidemiology



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SUMMARY
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Clostridium perfringens (formerly known as C. welchii, or Bacillus welchii) is a Gram-positive, rod-shaped, anaerobic, spore-forming pathogenic bacterium of the genus Clostridium. C. perfringens is ever-present in nature and can be found as a normal component of decaying vegetation, marine sediment, the intestinal tract of humans and other vertebrates, insects, and soil.  It has the shortest reported generation time of any organism at 6.3 minutes in thioglycolate medium.C. perfringens is one of the most common causes of food poisoning in the United States, alongside norovirus, Salmonella, Campylobacter, and Staphylococcus aureus. However, it can sometimes be ingested and cause no harm.Infections due to C. perfringens show evidence of tissue necrosis, bacteremia, emphysematous cholecystitis, and gas gangrene, which is also known as clostridial myonecrosis. The toxin involved in gas gangrene is known as α-toxin, which inserts into the plasma membrane of cells, producing gaps in the membrane that disrupt normal cellular function. C. perfringens can participate in polymicrobial anaerobic infections.  It is commonly encountered in infections as a component of the normal flora. In this case, its role in disease is minor.
The action of C. perfringens on dead bodies is known to mortuary workers as tissue gas. It causes extremely accelerated decomposition, and cannot be stopped by normal embalming measures. The bacteria is resistant to the presence of formaldehyde in normal concentrations.