Yamilet Gonzales ORS2022 DoE Media Optimization for Tissue Engineered Rabbit Articular Cartilage
Channel: Cell and Tissue Engineering Lab
Date: 2022-02-05

Tissue engineered cartilage is typically deficient in type II collagen. Defined chondrogenic media lacks 15 vitamins, mineral and growth factors that are physiologically required. Design of Experiments (DoE) media optimization was performed to identify conditions that stimulated type II collagen production. Over a two-fold increase was achieved.