How the tuberculosis bacillus takes advantage of the lipids of its host.
Channel: IPBS-Toulouse
Date: 2021-01-05

Responsible for 1.5 million deaths a year, tuberculosis is still the most deadly infectious disease today. The virulence of the bacterium responsible for this disease, Mycobacterium tuberculosis, is based in particular on its ability to modulate the metabolic pathways of macrophages. Scientists have shown that host-derived lipids generated during infection with M. tuberculosis alter the metabolic activity of macrophages, which results in a reduction in resistance to infection. 
These results are published in the journal Cell Reports.
For more information: http://www.ipbs.fr/how-tuberculosis-bacillus-takes-advantage-lipids-its-host