Strategic Guide for Young Adults with Acute Lymphoblastic Leukemia
Channel: JMU ISAT
Date: 2017-07-01

Full Title: Development of a Comprehensive Strategic Guide for Young Adults with Acute Lymphoblastic Leukemia by Zachary Yorio
Advised by: Dr. Stephanie Stockwell
Abstract: Acute Lymphoblastic Leukemia (ALL) is commonly considered a childhood disease, having a comparatively good prognosis with survival rates close to 90% (Rizzari et. al). However, for the few thousand adolescents and young adults (AYA) diagnosed each year in the United States, the overall survival rate drops down to as low as 46% (Muffly et. al.). A major reason for this discrepancy is that most young adults are treated on an adult chemotherapy regimen versus a more disciplined and intense pediatric inspired protocol. Some studies have shown as much as a 30% increase in overall survival rates for AYAs who receive modified pediatric treatment (Muffly et. al). Unfortunately, many adult oncologists are unaware of the treatment options available for younger patients under their care because these findings are recent and not well publicized. In an effort to improve the survival rate of AYA with ALL, I have created a guide for the leukemia community focused on actively pursuing the best course of personalized ALL treatment for AYA patients and providing firsthand insight into navigating the tumultuous months of intensive chemotherapy. Sections of this guide include: common chemotherapy drugs and their mechanisms of action, nausea management and hydration, chemoinduced fatigue and practical exercises, healthy eating throughout chemotherapy phases, and community support for patients during treatment. Compiling information from current scientific literature, specialized healthcare professionals, patient interviews, and life experiences as an ALL patient, this guide will bridge an audience gap within the current publications. This guide aims to empower AYAs to have informed dialogues with their physicians and feel engaged in the decisions concerning their treatment plan, as studies have shown the positive impact that patient activation and engagement has on health outcomes and medical care experiences.