Lindane | Wikipedia audio article
Channel: wikipedia tts
Date: 2018-12-07

This is an audio version of the Wikipedia Article:
Lindane


00:01:07 1 History and use
00:03:05 1.1 United States
00:03:50 1.1.1 Pharmaceutical uses
00:06:08 2 Human health effects
00:07:58 2.1 Cancer risk
00:09:19 2.2 Adverse reactions
00:10:21 3 Environmental contamination
00:14:55 3.1 Isomers



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SUMMARY
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Lindane, also known as gamma-hexachlorocyclohexane (γ-HCH), gammaxene, Gammallin and sometimes incorrectly called benzene hexachloride (BHC), is an organochlorine chemical and an isomer of hexachlorocyclohexane that has been used both as an agricultural insecticide and as a pharmaceutical treatment for lice and scabies.Lindane is a neurotoxin that interferes with GABA neurotransmitter function by interacting with the GABAA receptor-chloride channel complex at the picrotoxin binding site. In humans, lindane affects the nervous system, liver, and kidneys, and may well be a carcinogen. Whether lindane is an endocrine disruptor is unclear.The World Health Organization classifies lindane as "moderately hazardous", and its international trade is restricted and regulated under the Rotterdam Convention on Prior Informed Consent. In 2009, the production and agricultural use of lindane was banned under the Stockholm Convention on persistent organic pollutants. A specific exemption to that ban allows it to continue to be used as a second-line pharmaceutical treatment for lice and scabies.