Biophysical Chemistry 2018 - Lecture 10
Channel: Erik Lindahl
Date: 2018-04-14

The denatured state, properties of the molten globule. Why proteins must be polymers, and why they must be heteropolymers. Proteins are stable because of one clear low-energy state that is separated from the others by a stabilization energy (otherwise you would have multiple "native" states). Kinetics of protein folding. The folding barrier is entropy, while the unfolding barrier is enthalpy!