NITROGLYCERIN SUBLINGUAL TABLET, BASIC USE, DOSE, MECHANISM OF ACTION, SIDE EFFECTS, PHARMACOLOGY
Channel: PHARMAROCKS THE WAY OF SUCCESS
Date: 2021-01-31

NITROGLYCERIN SUBLINGUAL TABLET, BASIC USE, DOSE, MECHANISM OF ACTION, SIDE EFFECTS, PHARMACOLOGY

NITROGLYCERIN SUBLINGUAL TABLET, 
BASIC USE OF NITROGLYCERIN SUBLINGUAL TABLET,
DOSE OF NITROGLYCERIN SUBLINGUAL TABLET, 
MECHANISM OF ACTION OF NITROGLYCERIN SUBLINGUAL TABLET, 
SIDE EFFECTS OF NITROGLYCERIN SUBLINGUAL TABLET,
PHARMACOLOGY OF NITROGLYCERIN SUBLINGUAL TABLET,

Nitroglycerin Sublingual tablets
Nitroglycerin sublingual tablets are used to treat episodes of angina (chest pain) in people who have coronary artery disease 
That means narrowing of the blood vessels that supply blood to the heart

Nitroglycerin Sublingual tablets
It is also used just before activities that may cause episodes of angina in order to prevent the angina from occurring.
ANGINA PECTORIS is the medical term for chest pain or discomfort due to coronary heart disease. 

NITROGLYCERIN SUBLINGUAL TABLETS
Consistent with the symptomatic relief of angina, digital plethysmography indicates that onset of the vasodilatory effect occurs approximately 1 to 3 minutes after sublingual nitroglycerin administration and reaches a maximum by 5 minutes postdose.

Sublingual tablets
Sublingual medication administration are two different ways of giving medication by mouth.
Sublingual administration involves placing a drug under your tongue to dissolve and absorb into your blood through the tissue there

Nitroglycerin Sublingual tablets Working
Nitroglycerin works by relaxing the smooth muscle and blood vessels in our body. 
This increases the amount of blood and oxygen that reaches our heart. 
In turn, your heart doesn't work as hard. This reduces chest pain.

Nitroglycerin Sublingual tablets
The tablets kept in small, amber, tightly capped glass bottles in a refrigerator maintain their potency for three to five months if bottles are opened once a week. 
After five months the unused tablets should be discarded

how to use Nitroglycerin Sublingual tablets?
If you are using the sublingual tablet:
Do not cut, crush, chew, or swallow it.
Place the tablet under the tongue until it is dissolved.
If you take 2 or more tablets at a time, place all of the tablets in different places under the tongue at the same time.

Nitroglycerin Sublingual tablets dose,
Dosage forms & strengths
Tablet, SL
0.3mg
0.4mg
0.6mg
Powder, SL (gonitro)
0.4mg

Nitroglycerin Sublingual tablets
Angina Pectoris (Acute Relief)
0.3-0.6 mg SL every 5min up to 3 times; use at first sign of angina
Prompt medical attention needed if no relief
Dissolve under tongue or in buccal pouch; do not rinse mouth or spit for 5 minutes after administration

Nitroglycerin Sublingual tablets
Angina Pectoris (Prophylaxis)
1 tablet SL 5-10 minutes before activities likely to provoke angina attacks
Renal Failure
CrCl: 10-50 mg/min: 
Administer q24-72hr for prophylaxis
CrCl less than 10 mL/min: 
Administer q72-96hr for prophylaxis
q= each, every (from Latin quaque) q2wk

Side effects of Nitroglycerin Sublingual tablets
Headache, dizziness, lightheadedness, nausea, flushing, and burning/tingling under the tongue may occur. 
If any of these effects last or get worse, tell doctor or pharmacist.
Headache is often a sign that this medication is working.


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BASIC USE, DOSE, MECHANISM OF ACTION, SIDE EFFECTS, PHARMACOLOGY

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