Introduction to regulatory genomics and ISMARA
Channel: SIB - Swiss Institute of Bioinformatics
Date: 2020-05-11

This lecture gives an overview of the field of regulatory genomics and introduces the ISMARA tool. By modeling genome-wide gene expression and chromatin state data in terms of computationally predicted binding sites, Motif Activity Response Analysis (MARA) allows automatic inference of the key regulators, their targets, and their interactions from high-throughput data in any system. In recent years MARA has been completely automated into an integrated system (ISMARA) web server that allows any researcher to upload their data and obtain comprehensive predictions of key regulatory network structure in their data within an interactive graphical html interface. 
The video was recorded live during the course “Tools for regulatory genomics: using ISMARA, CRUNCH, EPD, and ChIP-seq tools to infer regulatory interactions from transcriptomic and epigenomic data” streamed on 7-8 April 2020.
Target audience: PhD students, postdocs and other researchers, from any scientific environment (academia, facilities, companies, etc.) working with regulatory genomics data. Any researcher that aims to make computational inferences about gene regulation from gene expression and chromatin state data. Purely experimental researchers, computational biologists and bioinformatic researchers
Speaker: Erik van Nimwegen, Professor at the University of Basel and SIB Group Leader.
Any questions about this talk? Contact: Erik van Nimwegen erik.vannimwegen@unibas.ch