Equol | Wikipedia audio article
Channel: wikipedia tts
Date: 2018-12-10

This is an audio version of the Wikipedia Article:
Equol


00:00:36 1 History
00:01:19 2 Chemical structure
00:02:05 3 Production in humans
00:03:23 4 Medical use
00:03:43 4.1 (iS/i)-equol producing bacteria
00:05:31 5 Pharmacology
00:05:40 5.1 Estrogen receptor binding
00:05:54 5.2 Pharmacokinetics
00:06:49 6 See also
00:08:03 7 References



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SUMMARY
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Equol (4',7-isoflavandiol) is an isoflavandiol estrogen metabolized from daidzein, a type of isoflavone found in soybeans and other plant sources, by bacterial flora in the intestines. While endogenous estrogenic hormones such as estradiol are steroids, equol is a nonsteroidal estrogen. However, only about 30-50% of people have intestinal bacteria that make equol. Equol can exist in two enantiomeric forms, (S)-equol and (R)-equol. (S)-Equol preferentially binds estrogen receptor beta.