Pathway Network Analysis of genes involved in Dominant Syndromes
Channel: ISCB-SC Webinars
Date: 2021-04-13

The autosomal dominant hearing loss is one of the unique phenotypical effects that is observed in multiple dominant syndromes. There are a set of genes that are associated with this sensorineural hearing loss and played a vital role in these disorders. The FGFR and FGF protein family of cell signaling have a significant role in this respect. The SALL1, Connexin 26, 30, 31, MITF, PTPN11, and SIX1 are closely related to syndromic and non -syndromic hearing loss. In this research study, we performed the biological pathway analysis using online tools and databases such as STRING, DAVID, and IPA (Ingenuity Pathway Analysis software), in order to find out the Cellular Enrichment Components and Biological Enrichment Process followed by gene network analysis. This research study explains the set of genes that are associated with human autosomal dominant deafness.