Neutrophilia and Neutropenia (Causes & Evaluation)
Channel: clinical pathology - Dr. Khalid
Date: 2023-09-27

Neutrophilia
An absolute neutrophil count greater than 7500/µl is termed as neutrophilia or neutrophilic leukocytosis.
Causes
1. Acute bacterial infections
2. Tissue necrosis
3.    Acute hemorrhage
4.   Myeloproliferative disorders
5.   Metabolic disorders: Uremia, acidosis, gout 
6.   Poisoning
Neutropenia: Absolute neutrophil count less than 2500/ µl is neutropenia. 
Causes
I.   Decreased or ineffective production in bone marrow:
2. Increased destruction in peripheral blood
3. Increased sequestration in spleen as in Hypersplenism.