Torque Testers for Pharmaceutical Manufacturing - MesaLabs
Channel: Life Scientific, Inc.
Date: 2018-02-21

The Virtual L&L Webinar Series is an educational webinar live series produced by Life Scientific featuring various equipment manufactures with the goal to educate and share the newest technologies in the industry. The increasing concern for efficiency and reliability in the pharmaceutical manufacturing field is influencing the industry to develop improved products and solutions to be released in the market. 

On this segment of our L&L Webinar Series, together with Gabor Szakacs from MesaLabs, we will discuss the applications of Torque Testers for Pharma Manufacturers. 

As we all know child-resistant caps and low-volume capping can be tough pills to swallow for some manufacturers; not Mesa! Unlike the competitors, our Torque testers can enable you to become compliant with the FDA’s CFR 21 Part 11. This code defines the criteria under which electronic records and signatures are managed, retained, and deemed trustworthy. The pharmaceutical industry often faces torqueing challenges with Tamper Evident Bands (TEB) such as those found on eyedrop bottles. 

Tune in to find out:
- How to accurately detect both small and large changes in the torque and angle during the removal of a closure;
- How to properly test tamper evident caps so both the thread break and the band break can be measured;
- How to find and report the torque it takes to strip out the threads when tightening your containers closure;

We offer the best tooling and solutions for accurately measuring torque that features a servo drive control, infinite chuck rotation, quick-change tooling, a color touchscreen interface, and faster cycle times. It boasts a corrosion resistant stainless-steel head enclosure and anodized aluminum frame construction.

For more information, visit https://lsi1.com/.


0:00 Introduction
2:14 About Mesa Laboratories, Inc.
4:33 Why is Cap Torque Important ?
5:11 Regulatory Overview
7:13 Safety First
9:14 Solution: Automated Torque Testing
10:57 Solution: Fully Automated Batch Torque Testing
11:20 Risk: Glass Projectiles, Hazardous Spills Solution: Optional Guard Assembly To protect the operator while testing bottles under pressure or bottes containing hazardous material
14:14 21 CFR Part 11 Electronic Record Keeping Compliance
19:40 Most Common Child-Resistant Closure types
21:17 Standards Related to Child-Resistant Closure Torque Testing
22:21 Optional Digital Topload Monitoring
24:22 CR Closure Testing examples
27:11 CGMP Considerations
31:07 Repeatable Automatic Closure Gripping
32:12 Cap Gripping Options
33:40 CGMP - Repeatability and Reproducibility concerns
35:29 Solution: Automated Testing with Automatic Product Detection and Product Specific Tooling
35:57 CGMP - Calibration, Verification, Validation
39:03 CGMP - Other Considerations
41:01 CGMP: Process Variation (Spills, seal issues, dwell time)
42:52 cGMP-Fully Automated Inline Torque Testing Closure Torque and Angle Tester (application and removal)
45:06 Examples of Fully Automated Inline Torque Angle Testers