STRING enrichment analysis: Brief introduction to the gene set enrichment functionality of STRING
Channel: Lars Juhl Jensen
Date: 30/08/2021

A brief introduction to the gene set enrichment analysis (GSEA) functionality of the STRING database. The presentation gives an overview of the different types of gene sets included in STRING, the two ways of using these for bioinformatics analysis and visualization of gene sets through the web interface. You may want to watch my short introduction to the core concepts of enrichment analysis first: https://youtu.be/2NC1QOXmc5o

0:00 Introduction: the STRING database and gene set enrichment analysis
0:27 Gene sets: Gene Ontology, pathways, protein domains, UniProt keywords, subcellular localizations, tissues, diseases, local network clusters, and publications
1:26 Basic list enrichment: protein list, STRING "multiple proteins" search and "analysis" tab, results tables, network visualization, and export of figures/tables
2:53 Ranked list enrichment: ranked genome-wide list, STRING "proteins with values/ranks" search, results tables, data visualization, and export of results

You can access all of this functionality at https://string-db.org