The Efficacy and Safety of Creatine for High Homocysteine
Channel: NutritionFacts.org
Date: 2020-09-07

Those on a healthy plant-based diet with elevated homocysteine levels despite taking sufficient vitamin B12 may want to consider taking a gram a day of contaminant-free creatine.

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This concludes my series on stroke risk. If you missed any of the videos here they are: 
• What to Eat for Stroke Prevention (http://nutritionfacts.org/video/what-to-eat-for-stroke-prevention)
• What Not to Eat for Stroke Prevention (http://nutritionfacts.org/video/what-not-to-eat-for-stroke-prevention)
• Do Vegetarians Really Have Higher Stroke Risk? (http://nutritionfacts.org/video/do-vegetarians-really-have-higher-stroke-risk)
• Vegetarians and Stroke Risk Factors—Vitamin D? (http://nutritionfacts.org/video/vegetarians-and-stroke-risk-factors-vitamin-d)
• Vegetarians and Stroke Risk Factors—Omega 3s? (http://nutritionfacts.org/video/vegetarians-and-stroke-risk-factors-omega-3s)
• Vegetarians and Stroke Risk Factors—Vegan Junk Food? (http://nutritionfacts.org/video/vegetarians-and-stroke-risk-factors-vegan-junk-food)
• Vegetarians and Stroke Risk Factors—Saturated Fat? (http://nutritionfacts.org/video/vegetarians-and-stroke-risk-factors-saturated-fat)
• Vegetarians and Stroke Risk Factors—Animal Protein? (http://nutritionfacts.org/video/vegetarians-and-stroke-risk-factors-animal-protein)
• Vegetarians and Stroke Risk Factors—Vitamin B12 & Homocysteine? (http://nutritionfacts.org/video/vegetarians-and-stroke-risk-factors-vitamin-b12-and-homocysteine)
• How to Test for Functional Vitamin B12 Deficiency (http://nutritionfacts.org/video/how-to-test-for-functional-vitamin-b12-deficiency)
• Should Vegetarians Take Creatine to Normalize Homocysteine? (http://nutritionfacts.org/video/should-vegetarians-take-creatine-to-normalize-homocysteine)
• The Efficacy and Safety of Creatine for High Homocysteine (http://nutritionfacts.org/video/the-efficacy-and-safety-of-creatine-for-high-homocysteine)

Now I’m assuming that nearly everyone who’s taking their B12 will have normal homocysteine levels, so these last two videos are just for the rare person that doesn’t, but those on a healthy plant-based diet with elevated homocysteine levels despite taking sufficient vitamin B12 should consider taking a gram a day of contaminant-free creatine (which would be about a quarter teaspoon).

OK, so where do you get contaminant-free creatine? You can’t rely on supplement manufacturers no matter what they say, since the regulation is so lax, so I would recommend going directly to the chemical suppliers that sell it to laboratories and guarantee a certain purity. Here are some examples from some of the largest companies in alphabetical order where you can get unadulterated creatine:
• Alfa Aesar (https://www.alfa.com/en/catalog/B25009/)
• Fisher Scientific (https://www.fishersci.com/shop/products/creatine-monohydrate-99-acros-organics-3/AC226790250)
• Sigma-Aldrich (https://www.sigmaaldrich.com/catalog/product/sigma/c3630?lang=en&region=US)
• TCI America (https://www.tcichemicals.com/eshop/en/us/commodity/C0396/)

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-Michael Greger, MD FACLM

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