other2.flv
Channel: OER Africa
Date: 2011-11-22

Cold agglutinins cause RBC clumping at temperatures below 37C (for example, at room temperature of 22C). This can result in an artifactual reduction of the RBC count, with increased MCHC and increased MCV. Warming the sample to body temperature reverses these changes.

Cold agglutinins may occur in lymphomas, auto-immune disorders, and with certain infections (infectious mononucleosis and severe Mycoplasma infection).

Rouleaux formation may also occur in some disorders at body temperature. The changes in the indices may be similar .
Any medical information in this material is intended to inform and educate and is not a tool for self-diagnosis or a replacement for medical evaluation, advice, diagnosis or treatment by a healthcare professional. Please speak to your physician if you have questions about your medical condition.