Granulopoiesis (leukocytes production). #leukocytes #neutrophils #granulopoiesis #GCSF
Channel: clinical pathology - Dr. Khalid
Date: 2024-02-03

#leukocytes production
#Granulopoiesis
#colony stimulating factors
#red bone marrow

• Leukocytes have two categories, granulocytes (neutrophils, eosinophils, and basophils), and agranulocytes (monocytes and lymphocytes).
• Granulopoiesis is the process of formation and maturation of granulocytes, a type of white blood cell involved in the immune response against bacterial and fungal infections. 
• Granulocytes include neutrophils, eosinophils, and basophils. 
• Granulopoiesis occurs primarily in the bone marrow, where hematopoietic stem cells differentiate and develop into mature granulocytes. 
• The process of granulopoiesis involves several stages of cellular development and maturation. 
• During this process, the cells undergo characteristic changes in their appearance and composition, including the development of specific granules in their cytoplasm.
• Granulopoiesis is regulated by various growth factors, such as granulocyte colony-stimulating factor (G-CSF), which stimulates the proliferation and differentiation of granulocyte precursors. 
• Understanding granulopoiesis is essential for studying and diagnosing disorders involving abnormal production or function of granulocytes, such as neutropenia (low neutrophil count) or leukemias. 
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