Botulinum neurotoxin type A resistance: An emerging problem
Channel: Research Outreach
Date: 2023-01-25

Botulinum neurotoxin A (BoNT-A), more commonly known as Botox, is used to treat medical conditions including dystonia and spasticity. It’s also increasingly used in cosmetic procedures. However, when used long-term or in high doses, immunoresistance is a real danger. A panel of experts is working together to increase awareness of these dangers, allowing patients to make informed treatment decisions.
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Article
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https://researchoutreach.org/articles/botulinum-neurotoxin-type-a-resistance-emerging-problem/
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Additional Information
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https://cosmeticmedicinecentre.com.au/our-team/dr-mary-dingley/
Dingley, M, et al, (2022) Emerging trends in botulinum neurotoxin A resistance: An international multidisciplinary review and consensus. Plastic and Reconstructive Surgery-Global Open, 10(6), e4407. https://journals.lww.com/prsgo/Fulltext/2022/06000/Emerging_Trends_in_Botulinum_Neurotoxin_A.46.aspx
Park, JY, et al, (2020) Neurotoxin impurities: A review of threats to efficacy. Plastic and Reconstructive Surgery-GlobalOpen, 8(1), e2627. https://journals.lww.com/prsgo/Fulltext/2020/01000/Neurotoxin_Impurities__A_Review_of_Threats_to.22....
Kerscher, M, et al, (2019) Incobotulinumtoxin A: A highlypurified and precisely manufactured botulinum neurotoxintype A. Journal of Drugs in Dermatology, 18(1), 52–57.
Jankovic, J, (2004) Botulinum toxin in clinical practice. Journal of Neurology, Neurosurgery and Psychiatry, 75(7),951–957. https://jnnp.bmj.com/content/75/7/951
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#neurotoxin 
#science 
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