Signature-tagged mutagenesis | Wikipedia audio article
Channel: wikipedia tts
Date: 2019-06-16

This is an audio version of the Wikipedia Article:
https://en.wikipedia.org/wiki/Signature-tagged_mutagenesis


00:00:45 Basic premise



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Speaking Rate: 0.741692797630104
Voice name: en-GB-Wavenet-A


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SUMMARY
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Signature-tagged mutagenesis (STM) is a genetic technique used to study gene function. Recent advances in genome sequencing have allowed us to catalogue a large variety of organisms' genomes, but the function of the genes they contain is still largely unknown. Using STM, the function of the product of a particular gene can be inferred by disabling it and observing the effect on the organism. The original and most common use of STM is to discover which genes in a pathogen are involved in virulence in its host, to aid the development of new medical therapies/drugs.