PEMPHIGUS VS PEMPHIGOID
Channel: DENTISTRY ’N MORE
Date: 25/07/2020

➡️In pemphigus, autoantibodies form against desmoglein Desmoglein forms the "glue" that attaches adjacent epidermal cells via attachment points called desmosomes  When autoantibodies attack desmogleins, the cells become separated from each other and the epidermis becomes "unglued", a phenomenon called acantholysis. This causes blistersthat slough off and turn into sores. In some cases, these blisters can cover a significant area of the skin.


➡️Pemphigoid is a group of rare autoimmune blistering diseases of the skin, and mucous membranes. As its name indicates, pemphigoid is similar in general appearance to pemphigus but, unlike pemphigus, pemphigoid does not feature acantholysis, a loss of connections between skin cells.[


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