Animation of ALP increases in cholestasis. #alp #animation #cirrhosis
Channel: clinical pathology - Dr. Khalid
Date: 2024-03-17

animation of how closure of bile duct increases alkaline phosphatase. 
Cholestasis increases ALP due to:
1. Closure of bile pass way
2. Increase synthesis in hepatocytes
3. Disaggregation and cleavage 
So that ALP is called cholestatic enzyme.