2022 -  Hacking the genome: how does it work, and should we?
Channel: MCH2022
Date: 2022-07-22

https://media.ccc.de/v/mch2022-16-hacking-the-genome-how-does-it-work-and-should-we-



Building on the very well attended DNA presentations ("DNA: The Code Of Life") at SHA2017, this talk will cover:

 * A brief recap what DNA is and how it works
   * It is surprisingly digital!
 * How reading DNA is within 'pro-sumer' reach now
   * (I might bring a live demo for after the talk)
 * An overview of DNA editing technologies (offline, and online: on living organisms)
    * Including the famous CRISPR-CAS, but also newer variants
 * How does such editing actually work in a lab?
 * The surprising lack of a definitive link between most DNA mutations and any effect
 * Could you hack your DNA? Will people start doing this?
   * Should we try to stop them?
 * Wild speculation on what this might mean for the future

The goal of this presentation is to provide real non-hyped information on what DNA editing is and what it might achieve. And since we are hackers, I hope to explain how a hackerspace could start reading DNA right now with USB-powered hardware. And finally, since no hacker can resist tinkering: could you hack your own genome, or your cat's, or improve on your favorite plant?

Building on the very well attended DNA presentations ("DNA: The Code Of Life") at SHA2017, this talk will cover:

 * A brief recap what DNA is and how it works
   * It is surprisingly digital!
 * How reading DNA is within 'pro-sumer' reach now
   * (I might bring a live demo for after the talk)
 * An overview of DNA editing technologies (offline, and online: on living organisms)
    * Including the famous CRISPR-CAS, but also newer variants
 * How does such editing actually work in a lab?
 * The surprising lack of a definitive link between most DNA mutations and any effect
 * Could you hack your DNA? Will people start doing this?
   * Should we try to stop them?
 * Wild speculation on what this might mean for the future

The goal of this presentation is to provide real non-hyped information on what DNA editing is and what it might achieve. And since we are hackers, I hope to explain how a hackerspace could start reading DNA right now with USB-powered hardware. And finally, since no hacker can resist tinkering: could you hack your own genome, or your cat's, or improve on your favorite plant?

bert hubert

https://program.mch2022.org/mch2022/talk/Y898KK/

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