Biomolecular structure | Wikipedia audio article
Channel: wikipedia tts
Date: 28/12/2018

This is an audio version of the Wikipedia Article:
https://en.wikipedia.org/wiki/Biomolecular_structure


00:01:19 1 Primary structure
00:03:11 2 Secondary structure
00:06:07 3 Tertiary structure
00:06:57 4 Quaternary structure
00:07:32 5 Structure determination
00:09:54 6 Structure prediction
00:12:56 7 Design
00:13:23 8 Other biomolecules
00:13:44 9 See also



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SUMMARY
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Biomolecular structure is the intricate folded, three-dimensional shape that is formed by a molecule of protein, DNA, or RNA, and that is important to its function.  The structure of these molecules may be considered at any of several length scales ranging from the level of individual atoms to the relationships among entire protein subunits. This useful distinction among scales is often expressed as a decomposition of molecular structure into four levels: primary, secondary, tertiary, and quaternary. The scaffold for this multiscale organization of the molecule arises at the secondary level, where the fundamental structural elements are the molecule's various hydrogen bonds. This leads to several recognizable domains of protein structure and nucleic acid structure, including such secondary-structure features as alpha helixes and beta sheets for proteins, and hairpin loops, bulges, and internal loops for nucleic acids.
The terms primary, secondary, tertiary, and quaternary structure were introduced by Kaj Ulrik Linderstrøm-Lang in his 1951 Lane Medical Lectures at Stanford University.