Complex traits | Wikipedia audio article
Channel: wikipedia tts
Date: 28/01/2019

This is an audio version of the Wikipedia Article:
https://en.wikipedia.org/wiki/Complex_traits


00:01:05 1 History
00:03:26 2 Methods
00:03:35 2.1 QTL mapping
00:04:58 2.2 GWAS
00:05:39 3 The genetic architecture of complex traits



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SUMMARY
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Complex traits, also known as quantitative traits, are traits that do not behave according to simple Mendelian inheritance laws. More specifically, their inheritance cannot be explained by the genetic segregation of a single gene. Such traits show a continuous range of variation and are influenced by both environmental and genetic factors. Compared to strictly Mendelian traits, complex traits are far more common, and because they can be hugely polygenic, they are studied using statistical techniques such as QTL mapping rather than classical genetics methods. Examples of complex traits include height, circadian rhythms, enzyme kinetics, and many diseases including diabetes and Parkinson's disease. One major goal of genetic research today is to better understand the molecular mechanisms through which genetic variants act to influence complex traits.