Quinolone antibiotic | Wikipedia audio article
Channel: wikipedia tts
Date: 27/03/2019

This is an audio version of the Wikipedia Article:
https://en.wikipedia.org/wiki/Quinolone_antibiotic


00:00:39 1 Medical uses
00:01:47 1.1 Children
00:04:06 2 Adverse effects
00:04:24 2.1 Boxed warnings
00:05:22 2.2 Tendons
00:06:19 2.3 Nervous system
00:06:43 2.4 Aortic dissection
00:07:17 2.5 Colitis
00:07:58 2.6 Other
00:09:59 2.7 Mechanism of toxicity
00:10:27 3 Interactions
00:11:47 4 Contraindications
00:13:27 5 Antibiotic misuse and bacterial resistances
00:15:58 6 Mechanism of action
00:18:02 6.1 Cellular uptake
00:18:55 7 Pharmacology
00:19:36 7.1 Pharmacokinetics
00:19:45 8 History
00:23:15 8.1 Generations
00:25:15 8.1.1 First generation
00:25:48 8.1.2 Second generation
00:26:47 8.1.3 Third generation
00:27:31 8.1.4 Fourth generation
00:28:31 8.2 Veterinary use



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SUMMARY
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A quinolone antibiotic is a member of a large group of broad-spectrum bactericides that share a bicyclic core structure related to the compound 4-quinolone. They are used in human and veterinary medicine to treat bacterial infections, as well as in animal husbandry.
Nearly all quinolone antibiotics in use are fluoroquinolones, which contain a fluorine atom in their chemical structure and are effective against both Gram-negative and Gram-positive bacteria. One example is ciprofloxacin, one of the most widely used antibiotics worldwide.