Research Highlight #3 - Dr. Molly Kupfer & Wei-Han Lin (Full)
Channel: FluidForm Bio
Date: 17/09/2020

In this Research Highlight, University of Minnesota’s Dr. Molly Kupfer and Wei-Han Lin describe their work in FRESH bioprinting human chambered muscle pumps (hChaMP) from gelatin methacrylate (GelMA) and collagen methacrylate (ColMA). Human induced pluripotent stem cells were printed in the ink and differentiated into cardiomyocytes inside the printed heart model structure to improve hChaMP function.

Paper:  https://pubmed.ncbi.nlm.nih.gov/32228120/

Intro - 0:58
Summary – 2:08
Printer Setup – 3:01
Optimizing Bioinks – 10:00
Printing iPSCs – 13:40
Heart Model – 15:42
Results - 19:17
Drug Testing on hChaMPs - 19:34
Analyzing hChaMPs - 23:16
Endothelialization - 24:23
Pitfalls in Experiments: 27:14
Advice for Students and Bioprinting - 29:19