DAC (chemotherapy) | Wikipedia audio article
Channel: wikipedia tts
Date: 06/06/2019

This is an audio version of the Wikipedia Article:
https://en.wikipedia.org/wiki/7%2B3_(chemotherapy)


00:00:51 1 Dosing regimen
00:01:00 1.1 Standard-dose cytarabine plus daunorubicin (DA or DAC chemotherapy)
00:01:14 1.2 Standard-dose cytarabine plus idarubicin (IA or IAC chemotherapy)
00:01:28 1.3 Standard-dose cytarabine plus mitoxantrone (MA or MAC chemotherapy)
00:01:42 1.4 Intensified versions



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SUMMARY
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"7+3" in the context of chemotherapy is an acronym for a chemotherapy regimen that is most often used today (as of 2014) as first-line induction therapy (to induce remission) in acute myelogenous leukemia, excluding the acute promyelocytic leukemia form, which is better treated with ATRA and/or arsenic trioxide and requires less chemotherapy (if requires it at all, which is not always the case).
The name "7+3" comes from the duration of chemotherapy course, which consists of 7 days of standard-dose cytarabine, and 3 days of an anthracycline antibiotic or an anthracenedione, most often daunorubicin (can be substituted for doxorubicin or idarubicin or mitoxantrone).