Multivariate integration of multi-omics data with mixOmics
Channel: Australian BioCommons
Date: 17/03/2024

Multi-omics data (eg. transcriptomics, proteomics) collected from the same set of biospecimens or individuals is a powerful way to understand the underlying molecular mechanisms of a biological system. 

mixOmics, a popular R package, integrates omics data from a wide range of sources into a single, unified view making it easier to explore and reveal interactions between omics layers. It overcomes many of the challenges of multi-omic data integration arising from data that are complex and large, with few samples (under 50) and many molecules (over 10,000), and generated using different technologies. 

Prof Kim-Anh Lê Cao, head of the mixOmics team, is delivering this webinar to outline the different methods implemented in mixOmics and how statistical data integration is defined in this context. She will demonstrate how these approaches are applied to analysis of different multi-omics studies and outline the latest methodological developments in this area. From a study of human newborns, to multi-omics microbiomes, and multi-omics in single cells, these examples illustrate how mixOmics is used to perform variable selection and identify a signature of omics markers that characterise a specific phenotype or disease status. 


Speaker: Prof Kim-Anh Lê Cao, Director of Melbourne Integrative Genomics, School of Mathematics and Statistics, University of Melbourne.

Date/Time: 6 March 2024,  1 - 2 pm AEDT/ 12 - 1 pm AEST / 12:30 - 1:30 pm ACDT / 10 - 11 am AWST

Who the webinar is for:
This webinar is for life scientists, bioinformaticians and anyone with an interest in exploration and integration of multiomics biological datasets.

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The slides from this webinar are available in our training materials collection on Zenodo.

https://zenodo.org/doi/10.5281/zenodo.10828245

See upcoming webinars and workshops on our website:
https://www.biocommons.org.au/webinars-workshops

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