Network biology: Connecting new omics data with existing literature
Channel: Lars Juhl Jensen
Date: 18/09/2023

Recording of my presentation from the excellent Boehringer Ingelheim Fonds alumni event "40 years with BIF". My presentation gives a broad overview of network biology, the STRING database, use of deep learning for mining literature and omics data, as well as network visualization.

0:00 Introduction: why networks and why networks in molecular biology
2:22 The STRING database: core biodata resource, evidence types, challenges, and scoring
13:55 From literature to networks: pre-trained transformers and fine-tuning for protein networks
19:20 From omics to networks: co-expression, the FAVA method, and understudied proteins
23:49 Network visualization: ridiculograms, Cytoscape stringApp, and virtual reality

Apologies for the suboptimal camera angle and audio quality — it is a GoPro recording and my lavalier recording unfortunately failed.