Read2Tree: Inferring phylogenetic trees from raw sequencing data
Channel: SIB - Swiss Institute of Bioinformatics
Date: 2023-11-16

What you will discover: How Read2TREE allows quick inference of phylogenetic trees directly from raw sequencing reads.

You are: Interested in comparative genomics and how to efficiently make phylogenetic trees. 

Speaker: David Dylus, Senior Scientist at Roche. Formerly Data Scientist at Comparative Genomics led by Christophe Dessimoz and Natasha Glover. 

Click to access specific sections of the talk: 

- 00:46 Introduction
- 02:16 A Standard pipeline
- 03:18 Read2Tree
- 03:52 How Read2Tree works 
- 04:47 Assessment of capabilities
- 09:03 Outputs from Read2Tree and speed
- 11:03 Using Read2Tree for pathogen surveillance
- 12:05 Conclusion 

Reference papers and resource

Dylus et al., Inference of phylogenetic trees directly from raw sequencing reads using Read2Tree. Nature Biotechnology 2023. DOI: 10.1038/s41587-023-01753-4 

Any questions about this talk? Contact David at 
Daviddylus[at]gmail.com 

More about the speaker:
David Dylus is a senior scientist within the Pharmaceutical Research and Early Development (pRED) division of F. Hoffmann-La Roche Ltd. Following his doctorate in Systems Biology at University College London under the guidance of Paola Oliveri, he continued in research as a Postdoctoral Fellow in the group of Christophe Dessimoz at the University of Lausanne’s Department of Computational Biology. Leveraging his diverse skill set, ranging from benchwork to data analysis and method/tool development, David transitioned to the pharmaceutical industry. His work now focuses on antibiotic resistance and autoimmune diseases and his current research interests encompass omic data analysis, tool and method development, and knowledge graphs. David is particularly interested in improving the identification of disease-related targets, with the ultimate goal of making a significant positive impact on patient outcomes.


Read the news on our website: https://www.sib.swiss/in-silico-talks/read2tree-inferring-phylogenetic-trees-from-raw-sequencing-data