Maize streak virus | Wikipedia audio article
Channel: wikipedia tts
Date: 04/11/2018

This is an audio version of the Wikipedia Article:
Maize streak virus

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SUMMARY
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Maize streak virus causes a plant disease, known as maize streak disease (MSD) in its major host. It is an insect-transmitted maize pathogen in the genus Mastrevirus of the family Geminiviridae that is endemic in sub-Saharan Africa and neighbouring Indian Ocean island territories such as Madagascar, Mauritius and La Reunion. The A-strain of MSV (MSV-A) causes sporadic maize streak disease epidemics throughout the maize growing regions of Africa.  
MSV was first described by the South African entomologist Claude Fuller who referred to it in a 1901 report as "mealie variegation".The development of conventionally resistant maize varieties has been a priority since the 1950s in Kenya, Nigeria, South Africa and elsewhere, with a good deal of success: however, there are several genes associated with resistance, and breeding is complex.  Transgenically resistant or genetically modified maize varieties were under development in South Africa, but the project has terminated without field trials of the candidate maize lines that were developed.
MSV is mainly transmitted by Cicadulina mbila Naude, but other leafhopper species, such as C. storeyi, C. arachidis and C. dabrowski, are also able to transmit the virus.
Typical of all mastreviruses, MSV's circular, ~2.7-Kb monopartite single-stranded (ss) DNA genome encodes only four proteins. Bidirectional transcription from a long intergenic region (LIR) results in the virion-sense expression of a movement protein (MP) and a coat protein (CP), and the complementary-sense expression of the replication-associated proteins, Rep and RepA. Whereas the MP and CP are involved in virus movement and encapsidation, Rep is an essential initiator of virus replication, and RepA is a regulator of host and viral gene transcription. Due to genome size restrictions, MSV usurps host DNA replication and double-stranded DNA break repair proteins to replicate its genome via, respectively, rolling-circle and recombination-dependent mechanisms.