High-throughput biology | Wikipedia audio article
Channel: wikipedia tts
Date: 2019-01-28

This is an audio version of the Wikipedia Article:
https://en.wikipedia.org/wiki/High_throughput_biology


00:02:00 1 Use of robotics
00:02:58 2 Use of microscopy and cytometry
00:04:15 3 Development of technology
00:05:15 4 See also



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SUMMARY
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High throughput cell biology is the use of automation equipment with classical cell biology techniques to address biological questions that are  otherwise unattainable using conventional methods. It may incorporate techniques from optics, chemistry, biology or image analysis to permit rapid, highly parallel research into how cells function, interact with each other and how pathogens exploit them in disease.
High-throughput biology serves as one facet of what has also been called "omics research" - the interface between large scale biology (genome, proteome, transcriptome), technology and researchers. High throughput cell biology has a definite focus on the cell, and methods accessing the cell such as imaging, gene expression microarrays, or genome wide screening. The basic idea is to take methods normally performed on their own and do a very large number of them without impacting their quality.
High throughput research can be defined as the automation of experiments such that large scale repetition becomes feasible. This is important because many of the questions faced by life science researchers now involve large numbers. For example, the Human Genome contains at least 21,000 genes, all of which can potentially contribute to cell function, or disease. To be able to capture an idea of how these genes interact with one another, which genes are involved in and where they are, methods that encompass from the cell to the genome are of interest.