Physostigmine | Wikipedia audio article
Channel: wikipedia tts
Date: 26/03/2019

This is an audio version of the Wikipedia Article:
https://en.wikipedia.org/wiki/Physostigmine


00:01:00 1 Medical uses
00:03:44 2 Pharmacology
00:04:30 2.1 Bioactivity
00:05:31 3 Synthesis
00:07:32 3.1 Biosynthesis
00:07:50 4 History
00:07:59 4.1 The Calabar bean
00:08:49 4.2 Western medicine's discovery
00:11:27 5 Side effects



Listening is a more natural way of learning, when compared to reading. Written language only began at around 3200 BC, but spoken language has existed long ago.

Learning by listening is a great way to:
- increases imagination and understanding
- improves your listening skills
- improves your own spoken accent
- learn while on the move
- reduce eye strain

Now learn the vast amount of general knowledge available on Wikipedia through audio (audio article). You could even learn subconsciously by playing the audio while you are sleeping! If you are planning to listen a lot, you could try using a bone conduction headphone, or a standard speaker instead of an earphone.

Listen on Google Assistant through Extra Audio:
https://assistant.google.com/services/invoke/uid/0000001a130b3f91
Other Wikipedia audio articles at:
https://www.youtube.com/results?search_query=wikipedia+tts
Upload your own Wikipedia articles through:
https://github.com/nodef/wikipedia-tts
Speaking Rate: 0.9851762709521894
Voice name: en-US-Wavenet-B


"I cannot teach anybody anything, I can only make them think."
- Socrates


SUMMARY
=======
Physostigmine (also known as eserine from éséré, the West African name for the Calabar bean) is a highly toxic parasympathomimetic alkaloid, specifically, a reversible cholinesterase inhibitor. It occurs naturally in the Calabar bean and the Manchineel tree.
The chemical was synthesized for the first time in 1935 by Percy Lavon Julian and Josef Pikl.  It is available in the U.S. under the trade names Antilirium and  Isopto Eserine, and as eserine salicylate and eserine sulfate. Today, physostigmine is most commonly used for its medicinal value. However, before its discovery by Sir Robert Christison in 1846, it was more prevalent as a poison. The positive medical applications of the drug were first suggested in the gold medal winning final thesis of Thomas Richard Fraser at the University of Edinburgh in 1862.