JWH-250 | Wikipedia audio article
Channel: wikipedia tts
Date: 11/12/2018

This is an audio version of the Wikipedia Article:
JWH-250


00:00:43 1 History
00:01:36 2 Legal Status
00:01:45 2.1 Australia
00:02:23 3 See also



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SUMMARY
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JWH-250 or (1-pentyl-3-(2-methoxyphenylacetyl)indole) is an analgesic chemical from the phenylacetylindole family that acts as a cannabinoid agonist at both the CB1 and CB2 receptors, with a Ki of 11 nM at CB1 and 33 nM at CB2. Unlike many of the older JWH series compounds, this compound does not have a naphthalene ring, instead occupying this position with a 2'-methoxy-phenylacetyl group, making JWH-250 a representative member of a new class of cannabinoid ligands. Other 2'-substituted analogues such as the methyl, chloro and bromo compounds are also active and somewhat more potent.