Method Lecture: Deriving biologically-informed, expression-based Polygenic Risk Scores (ePRS)
Channel: Ludmer Centre
Date: 03/11/2020

Expression-based Polygenic Risk Score Workshop

Guest Speaker: Patricia Pelufo Silveira MD, MSc, PhD

See: http://ludmercentre.ca/events/workshop-expression-based-polygenic-risk-scores/

Program, 3 November 2020
12:00-1:00 pm,  Method Lecture: Deriving biologically-informed, expression-based Polygenic Risk Scores (ePRS) 

1:00-1:15 pm: Break to get your lunch and a coffee 

1:15-1:30 pm Lunch session: Introduction to the free  CONP resources, where you can download the ePRS-5HTT and other open-source tools and open-science datasets.

1:30-2:30 pm,  ePRS-5-HTT Tutorial: What is a brain-region-specific expression-based polygenic score? Calculating the amygdala-based 5HTT ePRS in your data.

Dr Silveira is an Assistant Professor in the Department of Psychiatry at McGill University, leads the Environmental Adversity, Neurodevelopment and Mental Health theme-based group at the Douglas Mental Health University Institute, and is the Scientific Director (Int) of the Genomic & Epigenetics Pillar at the Ludmer Centre for Neuroinformatics & Mental Health.

Led by the Ludmer Centre, the ePRS Workshop is a joint collaboration with the McGill Seminar Series in Quantitative Life Sciences & Medicine and the Canadian Open Neuroscience Platform (CONP).