Biophysical Chemistry 2016 - lecture 10
Channel: Erik Lindahl
Date: 16/04/2016

The unfolded state. How do proteins fold/unfold? The molten globule. Side-chain packing & energy gap stabilization. Folding kinetics - how slow/fast is the folding and unfolding process? Folding corresponds to entropy barriers, unfolding to energy barriers. Kinetic vs. thermodynamic stability. Folding pathways, chaperones, transition states.