Tidymodels Approaches to Predicting Severe C diff Infections with Multicenter Cohorts
Channel: R Consortium
Date: 09/09/2022

From R/Medicine Conference 2022 

Allen Lee MD MS, Assistant Professor in the Division of Gastroenterology and Hepatology at the University of Michigan

Krishna Rao, M.D., M.S., Assistant Professor Biomarkers and outcomes in healthcare-associated infections at the University of Michigan

Main Sections

0:00 Introduction
0:40 Clostridioides difficile
1:31 Prior predictive models show poor performance on external validation
2:04 Aim, methods, primary outcome 
3:19 Using tidymodels 
4:20 Model development and evaluation
4:53 Results - Baseline demographics 
6:19 Primary outcome - disease-related complications from CDI
7:00 Models show good performance in predicting complicated CDI
7:54 Generalizability of models across centers and time 
9:00 Model performance based on CDI diagnosis 
10:42 Model performance stratified by race 
12:45 Conclusions 

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