Promotor (biology) | Wikipedia audio article
Channel: wikipedia tts
Date: 2019-05-02

This is an audio version of the Wikipedia Article:
https://en.wikipedia.org/wiki/Promoter_(genetics)


00:00:24 1 Overview
00:02:00 2 Identification of relative location
00:02:34 3 Relative location in the cell nucleus
00:03:04 4 Elements
00:03:13 4.1 Eukaryotic
00:05:03 4.2 Bacterial
00:06:43 4.2.1 Probability of occurrence of each nucleotide
00:07:36 4.3 Eukaryotic
00:08:14 4.3.1 Bidirectional (mammalian)
00:09:59 5 Subgenomic
00:12:29 6 Detection
00:13:15 7 Evolutionary change
00:13:56 7.1 De novo origin of promoters
00:14:30 8 Diabetes
00:15:05 9 Binding
00:15:41 9.1 Location
00:16:23 10 Diseases associated with aberrant function
00:16:53 11 CpG islands in promoters
00:17:57 12 Methylation of CpG islands stably silences genes
00:19:06 13 Promoter CpG hyper/hypo-methylation in cancer
00:19:50 14 Canonical sequences and wild-type
00:21:06 15 Diseases that may be associated with variations
00:22:14 16 Constitutive vs regulated
00:22:43 17 Use of the term
00:23:06 18 See also



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SUMMARY
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In genetics, a promoter is a region of DNA that initiates transcription of a particular gene. Promoters are located near the transcription start sites of genes, on the same strand and upstream on the DNA (towards the 3' region of the anti-sense strand).
Promoters can be about 100–1000 base pairs long.