Ending Aging: Living Beyond 130 Years - Yuri Deigin
Channel: Ameer Rosic
Date: 2019-10-06

Ending Aging: Living Beyond 130 Years - Yuri Deigin

In this episode, Yuri discusses new scientific breakthroughs in Aging. Can Stem cells and Yamanaka factors be the key to stopping aging? Can we use CRISPR technology to reverse the age of the cell and much more! 

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Guest

Yuri Deigin, MBA

 
http://youthereum.io
 
 
Yuri is a serial entrepreneur, an expert in drug development and venture investments in biotechnology and pharmaceuticals.

Yuri brings almost a decade of drug discovery and development experience from his previous role in a biotech startup where he oversaw research and development of original medicines aimed at treating diseases like Alzheimer's and rheumatoid arthritis. Yuri has a track record of not only raising over $20 million for his previous ventures but also initiating and overseeing 4 clinical trials and several pre-clinical studies, including studies in transgenic mice. He also has experience in pharmaceutical product launch, promotion, manufacturing and supply chain management.

Since 2013 Yuri also serves as a vice-president of the non-profit Foundation "Science for Life Extension" whose goal is the popularization of the fight against age-related diseases. To further this cause, Yuri frequently blogs, speaks, writes op-ed pieces, and participates in various TV and radio shows.

Yuri holds a B.Sc. from the University of Toronto and an M.B.A. from Columbia Business School.




Taking Points 


"Shinya Yamanaka has shown that an adult cell can be 'reprogrammed' back to embryonic state by OSKM transcription factors. Later research has shown that cells also undergo considerable rejuvenation in the process of reprogramming."

"CRISPR is a family of DNA sequences found within the genomes of prokaryotic organisms such as bacteria and archaea. These sequences are derived from DNA fragments of bacteriophages that have previously infected the prokaryote and are used to detect and destroy DNA from similar phages during subsequent infections."


"It is the first-line drug of choice for prevention and treatment of type 2 diabetes (T2DM). The effect of metformin on aging has been extensively studied, and has been associated with longevity in many rodent models. Metformin also extends the lifespan of nematodes, suggesting an evolutionarily conserved mechanism"





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