T-Cell Activation in Space | Wikipedia audio article
Channel: wikipedia tts
Date: 2019-05-03

This is an audio version of the Wikipedia Article:
https://en.wikipedia.org/wiki/T_cell


00:01:12 1 Types
00:01:21 1.1 Effector
00:01:56 1.2 Helper
00:03:24 1.3 Cytotoxic (Killer)
00:04:27 1.4 Memory
00:08:26 1.5 Regulatory (suppressor)
00:10:42 1.6 Natural killer T cell
00:11:46 1.7 Mucosal associated invariant
00:13:11 1.8 Gamma delta T cells
00:15:58 2 Development
00:18:20 2.1 Beta selection
00:20:07 2.2 Positive selection
00:23:24 2.3 Negative selection
00:26:17 3 Activation
00:36:13 3.1 Antigen discrimination
00:37:25 4 Clinical significance
00:37:35 4.1 Deficiency
00:38:54 4.2 Cancer
00:39:34 4.3 Exhaustion
00:40:42 4.3.1 During chronic infection and sepsis
00:42:49 4.3.2 During transplantation
00:44:06 4.3.3 During cancer
00:45:24 5 Research
00:45:32 5.1 Genetic engineering
00:46:15 6 See also



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SUMMARY
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A T cell, or T lymphocyte, is a type of lymphocyte (a subtype of white blood cell) that plays a central role in cell-mediated immunity.  T cells can be distinguished from other lymphocytes, such as B cells and natural killer cells, by the presence of a T-cell receptor on the cell surface. They are called T cells because they mature in the thymus from thymocytes (although some also mature in the tonsils). The several subsets of T cells each have a distinct function. The majority of human T cells, termed alpha beta T cells (αβ T cells), rearrange their alpha and beta chains on the cell receptor and are part of the adaptive immune system. Specialized gamma delta T cells, (a small minority of T cells in the human body, more frequent in ruminants), have invariant T-cell receptors with limited diversity, that can effectively present antigens to other T cells and are considered to be part of the innate immune system.