CH450 Chapter 8.2 Post-Translational Protein Modifications
Channel: Patricia Flatt
Date: 04/11/2020

In this lecture, we will focus on introducing some of the major types of post-translational modifications. These include small covalent, chemical modifications such as phosphorylation, hydroxylation, methylation and acylation (with a focus on acetylation of histones), and larger modifications including glycosylation, lipidation, and the addition of small peptides (including ubiquitin and SUMO). The SARS CoV-2 Spike protein is used as an example of protein glycosylation.