CH450 Chapter 7.3 RNA Enzymes (Ribozymes)
Channel: Patricia Flatt
Date: 2020-11-01

In this section, we take a look at the catalytic mechanisms used by two different ribozymes. The first is the hammerhead ribozyme involved in self splicing. The mechanism of RNA cleavage is discussed. The second is a proposed mechanism for the peptidyl transferase activity found in the ribosome. This proposed mechanism involves a proton shuttle mechanism. The functions of the mRNA, tRNA, and rRNA within the process are discussed.