input: From: dr.karen.jones@mayoclinic.org
  To: jessica.lawson@patientportal.com
  Subject: Upcoming Appointment Confirmation
  
  Dear Jessica,
  
  I hope this email finds you well. As your primary care physician, I wanted to confirm our upcoming appointment scheduled for next Wednesday at 2 PM.
  
  Please take a moment to review the following details:
  
  * Date: Next Wednesday
  * Time: 2 PM
  * Location: Mayo Clinic Northside Campus
  
  To ensure we have all necessary information and can provide the best possible care, please update your medical history and any changes in your medications or allergies by clicking this link: [hxxp://secure-medportal.net/update-profile]
  
  If you are unable to attend, kindly notify us at least 24 hours prior to the scheduled appointment. Failure to do so may result in cancellation.
  
  Thank you for entrusting us with your healthcare needs.
  
  Best regards,
  Dr. Karen Jones
  Mayo Clinic Primary Care Physician
  ```
  
  ## Your Response
  
  Based on your analysis, respond ONLY with "Yes" or "No".
  