RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Unravelling perspective-taking: Examining the influence of multiple constraints on perspective selection and multimodal behavior through a dynamical systems' approach'.

assistant: **Innovation**

Speakers routinely adapt their utterances and behaviour to converge on a shared perspective with their conversational partners. However, several aspects of perspective-taking are still underexplored. These include (i) the time course with which the partner’s perspective is considered, (ii) how the partner’s perspective interacts with other environmental and social cues, and (iii) how perspective choices are indexed by speakers’ behaviour. The proposed project addresses these issues by examining micro-behavioural measurements in (a) a set of mouse-tracking studies in which listeners respond to spatial instructions from an assumed partner, (b) a set of interactive studies in which dyads collaborate in a spatial task while multiple channels of their behaviour are sampled, and (c) a model based on the latter experimental data aiming to predict perspective from signatures in the dynamics of dyads’ multimodal behaviour. The empirical findings of the project can shed new theoretical light on the constraints of perspective-taking, but also supply clues for optimizing task and technology design. Dr Alexia Galati will pursue this project with Dr Rick Dale at the Cognitive and Information Sciences unit at the University of California, Merced (UCM), which comprises a critical mass of experts in dynamical systems. The embedded training in dynamical approaches involves novel and transferable technical tools that can be applied to activities ranging from user interface development, data visualization and synchronization, statistical analysis, and modelling. During the return phase, Dr Galati will transfer her new knowledge and skills to her collaborators and mentees at the University of Cyprus (UCY), under the supervision of Dr Marios Avraamides.


**Keywords:** dynamical systems, aud
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Flame Aerosol Reactors for Manufacturing of Surface-Functionalized Nanoscale Materials and Devices' (FLAMENANOMANUFACTURE).

assistant: **Innovation**

Nanotechnology research has been directed mostly to the design and synthesis of (a) materials with passive nanostructures (e.g. coatings, nanoparticles of organics, metals and ceramics) and (b) active devices with nanostructured materials (e.g. transistors, amplifiers, sensors, actuators etc). Little is known, however, about how well the unique properties of nanostructured materials are reproduced during their large scale synthesis, and how such manufacturing can be designed and carried out. A key goal here is to fundamentally understand synthesis of surface-functionalized, nanostructured, multicomponent particles by flame aerosol reactors (a proven scalable technology for simple ceramic oxide nanopowders). That way technology for making such sophisticated materials would be developed systematically for their efficient manufacture so that active devices containing them can be made economically. Our focus is on understanding aerosol formation of layered solid or fractal-like nanostructures by developing quantitative process models and systematic comparison to experimental data. This understanding will be used to guide synthesis of challenging nanoparticle compositions and process scale-up with close attention to safe product handling and health effects. The ultimate goal of this research is to address the next frontier of this field, namely the assembling of high performance active devices made with such functionalized or layered nanoparticles. Here these devices include but not limited to (a) actuators containing layered single superparamagnetic nanoparticles and (b) ultraselective and highly sensitive sensors made with highly conductive but disperse nanoelectrode layers for detection of trace organic vapors in the human breath for early diagnosis of serious illnesses.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Hybrid simulations of flow properties using atomistic – fluctuating hydrodynamics modelling for nanoconfined water' (HIPPOGRIFFE), addressing dissemination and exploitation.

assistant: **Impact**

The goal of this Marie Curie Individual Fellowship, entitled “Hybrid simulatIons of flow ProPerties using atOmistic – fluctuatinG hydRodynamics modellIng For nanoconFined watEr” (HIPPOGRIFFE) is to train a talented Experienced Researcher (ER), Dr. Ivan Korotkin through a research project focused on the development of novel multiscale modelling methods, which offer a unique tool for guiding the high-resolution measurements at nanoscale. The properties of nanoconfined water, such as density, the structure of hydrogen bonded network, local temperature, translational and rotational diffusions, and effective viscosity can be very different in comparison with the bulk water properties. These differences must be understood and accounted for if the high-precision measurement techniques such as atomic force microscopy (AFM) are to be used in confidence for nanoscale imaging and control of interfacial and nanoconfined liquid flow. The ER will be trained in the field of multiscale modelling and manipulation of nanoconfined flows. He will receive access to a unique specialist training at the host institution, School of Engineering and Materials Science, Queen Mary University of London (Dr. S. Karabasov), and at academic secondments: Aston University (Dr. D. Nerukh), Universidad Autónoma de Madrid (Prof. R. Delgado Buscalioni), and Durham University (Dr. K. Voïtchovsky). The results of the HIPPOGRIFFE project will contribute to the enhancement of scientific excellence in European research. The results of the project will also find their ultimate use in industry, e.g. through providing recommendations for refined applications of the AFM technology for nanoscale imaging and developing new computational routines for the software companies who specialise in multiphysics modelling. In ad
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'High-intensity focused ultrasound intracardiac ablation with real-time monitoring using shear-wave imaging'.

assistant: **Concept**

Arrhythmias are a major cause of death and disability worldwide and their prevalence is expected to rise with the aging of the population. Recent technological advances have led to the development of new treatments based on radio-frequency (RF) catheter ablation to treat and even cure these conditions. However, challenges in treatment persist. RF ablation is currently performed via direct contact with the endocardium, limiting the depth of tissue injury unless high temperatures are used, which lead to higher risks of clot formation. Another major limitation is the lack of combined imaging modality for real-time monitoring of the treatment and for accurate assessment of the lesion extent. Our objective is to construct an ultrasound-based intra-cardiac ultrasound therapy/imaging system that can perform ablation using high-intensity focused ultrasound (HIFU) and can monitor the size and temperature of the ablation lesion using shear wave imaging (SWI). The specific aims of are 1) to develop an intra-cardiac hybrid system to perform HIFU, real-time temperature and lesion size monitoring using SWI, 2) Validate and optimize the imaging/therapy system in an animal model and 3) Demonstrate the feasibility of real-time RF ablation monitoring in patients using SWI.  This project is tailored to facilitate the transfer of knowledge of the experienced researcher in imaging the with ultrasound at very high frame-rate the electromechanical properties of the heart. Upon completion, this project will result in the development of an intra-cardiac ultrasound system that allows performing non-contact ablation transmurally while monitoring the lesion site growth and temperature in real time.  The capability of ablating at any location in the thickness of the myocardium while simultaneously
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Revealing the mechanics of sub-critical rock cracking of mountains cliffs from environmental forcings by imaging stress cycles from dense acoustic arrays', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

The general idea that a rock mass cracks when the external stress-loading exceeds the rock strength, leading to catastrophic failure (critical cracking), is challenged when considering outcrop erosion. Many observations in the field and the laboratory evidence slow, incremental crack developments well below the yield stress of the material, for which repetitive stress load and fatigue induce progressive failure, also called sub-critical cracking. It is largely accepted that the weather (temperature changes, rain, frost) is a major source of stress cycles and slow cumulative damage, but the literature shows too limited quantitative field observations to confirm the mechanics behind rock outcrop cracking. Today, we cannot predict rockfalls nor quantify the relation between daily or seasonal weather forcings to rock crack production. And yet, rock fracturing plays a leading role in most surface processes, from landscape building to vegetation, hydrology and natural hazard prediction. There is an urgent need to reveal the mechanics of sub-critical failure within rock outcrops. Fracturing processes initiate and develop at small scales (from the grain size to a few mm), and meteorological forcing evolve over daily to seasonal time scales, but existing field observation tools hardly meet these scales. In order to lift this issue, the project will deploy an original active multisensory acoustic imaging technique on natural rock outcrops, to map and monitor stress changes and crack production (in m2/m3/time) over timescales ranging from a few hours to a few months, with a centimetric spatial resolution and a stress sensitivity down to a few kPa. Stress will be deduced from acoustic waves, thanks to the acousto-elasticity principle, allowing us to determine the physics of sub-cri
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'REAL TIME DETECTION AND CONTROL OF WELLBORE INSTABILITY' (1994-1998), addressing dissemination and exploitation.

assistant: **Impact**

The aim of the project is to demonstrate that a real product for monitoring and controlling wellbore instability will reduce drilling cost by providing i) information on the evolution of the wellbore during the drilling process ii) recommendation on mud weight, mud property, mud circulation, casing point and well direction. This product, which involves measurements acquired while drilling, must be robust and easy to use. It is an extension to an existing commercial simulator, IMPACT, incorporating results of research recently completed at Schlumberger Cambridge Research and TNO. The demonstration will be carried out in the North Sea Everest Complex where drilling problems are significant .Work has been completed according to schedule. The field demonstration of the real-time wellbore stability control process has been carried out in Amoco's Valhall Field of the North Sea. The process made a significant impact on the drilling of the targeted interval.The tool will be a system running at or in close contact with an active drilling rig, accepting data concerning drilling conditions, diagnosing problems of hole stability, and recommending the best method to overcome them. The diagnosis will also be used to update a mathematical model of the wellbore, to improve drilling performance on subsequent wells. The project is in six phases, and uses one of Amoco's North Sea fields as a source of data and, in the later stages as a demonstration area for the tool during the drilling of new wells. Phase I is collection and assembly of data for the field, including seismic, drilling and logging records. This allows a picture to be built up of the drilling and hole stability problems encountered in the field, and also generates datasets on which the software can be tested. Phases II and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Autistic Perception and the Predictive Role of Visual Experience'.

assistant: **Innovation**

Localizing stimuli in our environment is crucial for virtually all motor, perceptual and cognitive tasks. The brain is constantly confronted with sensory information that must be processed efficiently to facilitate appropriate reactions. One way of improving processing efficiency is to predict incoming sensory information based on previous experience. However, the way in which prior experience (""priors"" within the Bayesian framework) and current sensory inputs are combined varies between individuals. This project is based on state-of-the-art eye-tracking experiments driven by recent theoretical developments in Autism Spectrum Disorder research. While abnormalities in saccade accuracy in ASD have often been reported, here we investigate the novel hypothesis that impairments in saccade efference-copy processing are responsible for the build-up of weak priors. The project focuses on the dynamic processes by which the brain samples visual scenes to update its model. Eye-movement and pupillometry indices will be used to track differences in visual behavior between ASD and matched controls. The project is intrinsically multidisciplinary, combining educational psychology, neuropsychology, psychophysics, eye-movement and pupillometyry measurement, and virtual reality. This proposal includes both the transfer of knowledge from the host institution and the training of the candidate in new advanced techniques. The results have the potential capacity to lead to a deeper understanding of the perceptual symptoms of ASD, and may also provide a biomarker of ASD. Finally, the project will provide a new theoretical framework within which to conceptualize the role of priors and predictions in visual behavior in normal and pathological eye-movement development which will lay the groundwo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Drug solution for bone fracture nonunions', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Bone fracture nonunion (FNU) is one of the leading unmet orthopaedic clinical needs, resulting in billions of healthcare costs annually without any drug approved by regulatory agencies for this debilitating indication. Due to considerable shortcomings of the current best practices in treating bone FNUs, patients are facing increased risks and morbidity. The market has available only bone substitutes and enhancers with limited clinical efficiency, highlighting an essential need for more effective therapies. Genera Research is on its way to filling the gap with its globally patented OSTEOGROW-C product: a novel biological drug transforming patients blood into bone. The proposed OSTEOforUNION project aims to develop and commercialize OSTEOGROW-C, an innovative drug for bone regeneration. OSTEOGROW-C is a novel treatment option for bone FNUs, an implant composed of an active substance - recombinant human bone morphogenetic protein 6 (rhBMP6) incorporated in an autologous blood coagulum (ABC) where tricalcium phosphate (TCP) ceramics is added as a compression resistant matrix (CRM). This combination forms a personalized implant that catalyzes bone growth at the implantation site. It is easily prepared in the operating room from the patient's blood without the need for a painful bone harvesting procedure, as in current treatment practices, with associated complications and morbidities (donor site pain, infection, nerve injuries, blood loss or iliac wing fracture etc.) and related additional healthcare costs. OSTEOGROW-C targets the global FNU market, which serves 6M patients yearly. Key overlapping markets are Fracture Fixation, Orthobiologics, Bone Grafts, and BMP. OSTEOGROW-C's unique stance promises to revolutionize the FNU market. The initial market entry will concentrate
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'BIM based fast toolkit for Efficient rEnovation in Buildings' (BIM4EEB) under Horizon 2020.

assistant: **Objectives**

BIM4EEB aims to foster the renovation industry by developing an attractive and powerful BIM-based toolset able to support designers in the design and planning phase, construction companies to efficiently carry out the work and service companies to provide attractive solutions for building retrofitting. Additionally, public and private owners will be able to use a tool that eases decision making and asset management, thanks to the exploitation of augmented reality and the use of updated digital logbooks. BIM4EEB will deliver an innovative common BIM management system with linked data and a set of tools. This toolkit is the basic instrument for increasing semantic interoperability between software and stakeholders involved along the overall renovation process (design, planning, construction, performance assessment and management). End-users of the entire renovation process will actively participate to the development phases ensuring the full matching of project deliveries with the market expectations and maximizing the value of what is produced. In particular, two public administrations and two general contractor companies will validate the toolset in a social housing setting and private residential buildings in Italy, Poland and Finland. Inhabitants will benefit by the increase of building performances, quality and comfort.A focused market analysis will ensure effective market strategies. BIM4EEB will focus on delivering high levels of modularity between tools enabling the commercial exploitation as standalone products or services, or as part of a consolidated market offering, usable for AEC end users, consulting services or by other IT business areas if required. The developed best practices and guidelines for BIM adoption for public administrators and private stakehold
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Adaptation of human brown adipose tissue to overnutrition' (BATON), addressing dissemination and exploitation.

assistant: **Impact**

Brown adipose tissue (BAT) is a highly thermogenic tissue whose main function is to produce heat to maintain mammals’ body temperature. In humans, it has long been believed that BAT is either absent or irrelevant in adults. However, a decade ago, several independent research groups confirmed the presence of metabolically active BAT in human adults. In rodents, BAT plays a key role in the adaptation to overfeeding, protecting murine from diet-induced obesity. Whether this phenomenon also occurs in humans is still unknown. To date, technical limitations for in vivo human BAT assessment have precluded us from adequately studying it.The BATON study will first aim to develop a new method to accurately measure human BAT volume and thermogenic capacity in vivo. New approaches based on recent advances in human BAT metabolism (i.e. BAT’s unique ability to burn its own intracellular triglycerides and the recently discovered, and unexpected, capacity of human BAT to be activated through β2 adrenergic receptor agonism) will be tested in a randomized cross-over study. Ten young healthy adults (18-30 years old, 5 men and 5 women, with a body mass index <25kg/m2) will undergo 3 experimental sessions including sequential positron emission tomography-computerized tomography and magnetic resonance imaging and spectroscopy scans.Later, the newly develop method(s) will be used to measure BAT volume and thermogenic capacity changes in response to a 4-week 40% overfeeding, in a proof-of-concept overfeeding pilot study. Twelve healthy adults (18-30 years old, 6 men and 6 women) with a body mass index <25kg/m2 will participate in this randomized controlled trial. After baseline assessments, participants will be randomized (blocking the randomization by sex) to a 4-week weight maintenance diet