RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Experiences of Abortion in Black Rural Brazil' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

The 2023 Brazilian national abortion survey highlighted that, despite legal restrictions, abortion remains prevalent, with one in every seven women undergoing the procedure by age 40. A racial breakdown of the data revealed that Black women were 46% more likely than white women to have an abortion.  Access to safe abortion is an essential reproductive rights issue and a vital public health concern. The magnitude and criminalization of abortion in Brazil exacerbate the already existing class, gender, and race inequalities in the country. Reproductive health research shows that Black women face the greatest individual and institutional barriers when attempting to access sexual and reproductive care services. This group is also more likely to die from abortion-related causes and face arrest and stigma. These further stark racial disparities make access to safe abortion a matter of racial justice in Brazil. Studies on abortion in Brazil with a racial focus are scarce.  In particular, little is known about how Black people in rural communities navigate and challenge legal restrictions, cultural stigma, and racial discrimination when seeking an abortion in a setting that is structurally designed to exclude them and has historically despised their fertility. This project aims to understand the experience and processes of accessing and having an Abortion in Black Rural Brazil through the lens of local pregnant people. Based on anthropological and interdisciplinary studies on reproductive health, gender, and critical race theory, this timely research will investigate how they confront the multifaceted challenges surrounding abortion access and reproductive rights in contemporary Black rural Brazil. By drawing on ethnographic fieldwork this study will generate practical evidence
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'An engine management system suited to meet the regulation EURO2000 by means of an enhanced digital core' (CORE2000) under Fourth Framework.

assistant: **Objectives**

The Project Core2000 aims to develop and to assess a Cost Effective Engine Management System optimised to meet the Euro2000 regulations for gasoline engines.- Based on a highly performant but cost efficient 'MicroController' with broad market applicability - By means of enhanced approaches in Control Methods as well as in Sensor Components.The European regulation Euro2000 targeted for the time period after 2000 will intensify the current level of European pollution control regulation in two directions:1 Requiring lower emission level for all three regulated pollutants: CO, HC, NOx.2 On board diagnostic to check emission control system in order to identify high polluters.To yield this goal the Engine Management System to be developed and constructed under this Project will require not just innovative approaches on fairly all core elements but a highly optimised overall systems-partitioning and integration of its elements. To resolve this target a coherent approach for software, hardware and components targeted by means of a highly collaborative activity in-between the Partners: a Car Manufacturer, a System-Suppliers, a Component-Suppliers and a Software-Supplier. The work to achieve this will be performed in three Phases. Initially the system requirements will be evaluated and the System, the MicroController, the target improvements of the Control Software and the necessary improvements of the software development tools and means will be specified. In a second phase of the Project the System Hardware, its Control Software and the MicroController will be developed in parallel, however in close collaboration. This will include: 1 To reorganise the overall functional partitioning of the existing Engine Management System, i.e. replacement of hardware including sensors by sig
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'The development of new diagnostic tests, new tools and non-invasive methods for the prevention, early diagnosis and monitoring for haematopoietic stem cell transplantation' will create measurable scientific, societal and economic impact aligned with Sixth Framework.

assistant: **Impact**

Over 7000 allogeneic haematopoietic stem cell transplants (HSCT) are carried out each year in Europe alone, as a treatment for leukaemia and lymphoma. Techniques and cure rates are improving but the overall survival rate remains between 40-60%. This project will develop new proteomic, biological and genomic tests and tools for early diagnosis and monitoring of patient response to novel therapeutics for the most severe complication of HSCT; graft versus host disease (GvHD) and will bring to the clinic a new generation of diagnostics that will significantly improve HSCT therapy and patient outcome. The Consortium unites 5 European SMEs with expertise and markets in genomic and proteomic testing, diagnostic assay development and biochips, with clinical partners selected for their world leading research in HSCT and access to clinical samples and patient groups. The project will focus on the role of relevant genes and biomarkers associated with acute and chronic GvHD, using retrospective samples from established biobanks and prospective clinical trials to: 1) Identify novel bio and genomic markers for diagnostics 2) Develop novel diagnostic tools using genomics, proteomics, in vitro bioassays and biochips 3) Test the new diagnostics in animal models & on clinical samples 4) Exploit the new tools for commercial use The above will be realised by: ' Development of diagnostic tests using single nucleotide polymorphism (SNP) analyses (SME IMGM), based on results from previous EC funded research (EUROBANK, TRANSEUROPE). - Using proteomics via mass spectrometry (evaluation/development of diagnostic patterns (SME MOSAIQUES), ELISA kits (SME APOTECH) and protein biochip prototypes (SME ORLA), for the development of fast high throughput technologies. - Development of novel reagents fo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'EU TRADE AND INVESTMENT POLICY' to be submitted under Horizon 2020.

assistant: **Abstract**

International trade and investment are of considerable economic and political importance for Europe. The EU is negotiating trade agreements globally, involving the abolition of tariffs, the reduction of non-tariff barriers to trade, and the introduction of dispute settlement mechanisms. However, the example of the controversial TTIP has shown the challenges of EU trade policy. The objective of the EU Trade and Investment Policy ITN (EUTIP) is to foster interdisciplinary research into the evolving international trade policy of the EU with a view to create a significantly increased European knowledge base and research capacity on EU law and policy of the regulation of international trade through free trade agreements (FTAs) with third countries, thus helping Europe to safeguard the benefits of international trade (wealth, jobs, etc.) while addressing  the challenges of its regulation (competence, democracy, accountability, environmental- and labour, standards, etc.). It is argued that the EU trade and investment policy pursued through FTAs will lead to the evolution of an entirely new legal sub-discipline closely related to and originating in EU law and international trade law. This new field of law will be wide-ranging, including aspects already addressed in existing FTAs and fields of trade and competition law currently regulated in the Treaty on the Functioning of the EU (TFEU), the relevant decision-making mechanisms, the relationship between the relevant legal systems, and dispute settlement. Moreover, the ITN investigates Transatlantic agreements as precedents and possible templates for third generation trade agreements of the EU with other parts of the world. The network is an interdisciplinary, intersectoral collaboration pooling world-leading researchers and prac
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Quantum walks in superconducting networks'.

assistant: **Concept**

I propose to build a general purpose continuous quantum walk platform using superconducting devices (resonators, qubits and SQUIDS). This system will include up to 40 sites and will implement basic quantum simulation algorithms, generalized interferometry and explore the quantum-classical boundary for many-particle entangled systems.Quantum walks (QW) are a novel scheme for quantum information processing. The core idea is to encode the problem into a network and propagate quantum particles within. The entanglement of the many-body state due to interference between sites of the network brings, at the appropriate time, to a desired answer/observable. Recent implementations with optical photons or trapped ions and atoms have brought this theoretical process to the forefront of fundamental and applied quantum engineering.In parallel, superconducting devices are experiencing a renaissance due to modern understanding of materials, fundamental physics of superconductivity and fabrication techniques. The coherence times of superconducting qubits have improved by almost 5 (!) orders of magnitude over the past ten years. Recent developments include single microwave sources and detectors, quantum-limited amplifiers, heterodyne techniques for measurement and state tomography.Building such a network involves significant challenges, both fundamental and technical. On the fundamental level I intend to improve coherence times of our devices by advanced material science characterization, simulation tools and rapid turn-around characterization. My group will build a ""quantum compiler"" system for designing new layouts, bridging abstract design to implementation. On the technical level we will implement a flip chip bias circuit to overcome site inhomogeneity and for evolving and measurin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Precise Parameter Estimation of Gravitational Waves Sources of Low and Medium Frequencies'.

assistant: **Objectives**

The operation, construction and new projects of a number of new and next-generation gravitational  wave detectors are currently underway. They will constitute a network of ground- and space-based detectors in a near future, aiming at detecting Gravitational Waves (GWs) generated by different astrophysical and cosmological sources. In particular ground-based detectors will be sensitive to sources of high and medium GW frequencies, whereas the space-based ones will be more sensitive to that of medium and low frequencies.Binary systems composed of a Stellar Compact Object (SCO) orbiting a Massive Black Hole (MBH) are one of the main sources emitting at low GW frequencies. Due to the differences between the masses of their components, these systems are named Extreme-Mass-Ratio Inspirals (EMRIs). During the last year of emission, the SCO tracks the geometry deep in the strong-field region of the MBH, mapping the MBH spacetime in the GWs. Then, by looking at their waveforms, we can determine, with high accuracy, the physical parameters characterising the system. However, the different studies carried out in the past have not yet attempted to perform a systematic parameter estimation analysis for EMRIs. The research work  that we propose will set the basis for a robust systematic parameter estimation study, including realistic physical situations that will account for modifications due to different astrophysical scenarios. Moreover, since the theory ruling MBHs may not be General Relativity, we will also consider other gravitational theories, filling an existing gap in the literature.Finally, we also expect that this work will be also relevant to study GW sources of middle frequency, like Intermediate Mass-Ratio Inspirals, which are EMRI like systems but with an intermediate m
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Positioning of an artificial centrosome in a dynamic actin network' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

The centrosome is one of the main microtubule-organizing centers in cells, spawning filaments that define the cells shape and polarity. Peculiarly, it is almost always positioned either at the center of the cell or at its periphery, rarely in between. Precise centrosome positioning is crucial: when positioned in the center, the centrosome has the fundamental task of integrating information from the whole cell via the microtubule network. Instead, its swift transition to the periphery is a key step of cell differentiation and polarization. Yet, despite its importance, the mechanism regulating this transition is unknown: several factors are probably involved and regulated in the process, including forces due to molecular motors or to the dynamics of the actin and microtubule networks. In particular, the role of the actin network inside which the microtubules are embedded is starting to be understood as a fundamental player, yet the precise physical mechanism is not understood. This project consists in resorting to the in vitro reconstitution of both the actin and the microtubule networks at the same time, to study their interaction in a minimal biomimetic system. Using an artificial centrosome spawning microtubules and embedding it inside an artificial actin cortex in a dynamic state, adding molecular motors to provide activity and confining it inside cell-sized microwells, we aim to understand how a sharp center to periphery transition can occur and what are the physical processes involved. The possibility to add different purified components one at a time will allow exploring what role factors such as motor- and polymerization-based forces or the mechanical coupling to a contractile actin network play, individually and combined, in defining and controlling precise centr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Regulation of cellular proliferation in chronic neurodegenerative disease: Microglial proliferation and neurogenesis in prion disease' under Seventh Framework.

assistant: **Concept**

An important aspect of chronic neurodegenerative diseases, such as Alzheimer’s, Parkinson’s, Huntington’s or prion disease, is the generation of an innate inflammatory reaction within the central nervous system. Microglial cells play a leading role in the development and maintenance of this inflammatory reaction, showing enhanced proliferation and morphological activation. Moreover, during neurodegeneration and inflammation, the mechanisms that control neural stem cell biology are altered and may also affect disease progression, causing impaired neural stem cell renewal, migration and differentiation. Since these proliferative responses are both involved in neurodegeneration they may share common or perhaps antagonistic regulatory pathways.In this project, using a tractable laboratory model of neurodegeneration (murine prion disease), we will study the time-course and molecular regulation of microglial and neural stem cell proliferative responses. Moreover, we will analyze the role of the inflammatory milieu in the regulation of the proliferative responses, in order to throw light on the progression of chronic neurodegeneration. These objectives will be addressed using a multidisciplinary technical approach, combining the use of transgenic animal models with cell culture systems, analyzed by cellular and molecular biology techniques. Furthermore, we will cross-validate our studies with the analysis of the microglial and neural stem cell proliferative responses in post-mortem brain samples from Alzheimer’s disease patients. This powerful combined approach would permit us to obtain results that will contribute to the understanding of mechanisms that drive progression of chronic neurodegeneration.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Bio Ring Diagnostics', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Tuberculosis (TB) is one of the largest world health problems: annually 10 million people become ill and 1.5 million people die from TB. According to World Health Organisation (WHO) this is largely attributed to the fact that 4 million TB patients are not diagnosed each year, due to lack of a good diagnostic tests. According to European Centre for Disease Prevention and Control (ECDC) in 2017 323.000 new cases of TB have been registered and 32.000 Europeans died from TB. On global scale all pharmaceutical companies, clinical research organisations and life science research institutes depend on surface plasmon resonance (SPR) instruments for swift (bio-molecular interaction) detection of diseases and for specific research. SPR is an inherently expensive technique and therefore limited available. There is globally a large unmet need for a cost-effective instrument with similar functionality and sensitivity as SPR and multiplexing capabilities for measuring such real‐time biomolecular interactions. Delta Diagnostics has developed an instrument capable of swift bio-molecular interaction detection. This instrument employs Photonic Integrated Circuits (PICs), more specifically so-called ring resonators. Within this project Delta Diagnostics sets out to study the feasibility of the development of a minimal viable product (MVP) of this low cost instrument. This instrument can rival conventional SPR sensors, yet at a fraction (close to a tenth) of the costs. The MVP will make label-free biomolecular interaction analysis technology globally available in a small and cost-effective device. The platform technology behind it, will further contribute to the development of even smaller and more versatile and more accurate point of care (portable) diagnostics. The product will disrupt t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Sixth Framework proposal on 'Improvement of competitiveness of the labour market and its entities'.

assistant: **Innovation**

The project aims at initiating cooperation among scientific partners from countries of the European Union, which will result in transfer of knowledge in the field of widely understood labour market. Implementation of the project will be based on its main objective: to improve competitiveness of the European labour market and its entities.The project results will support implementation of priorities of the European Commission established in the Lisbon strategy: to cause the European economy to become the most competitive and innovative economy in the world by 2010. In order to achieve this objective the following scientific actions will be carried out: estimation of competitive properties of work resources in Europe, an analysis of behaviour of companies on labour market and their competitiveness together with an analysis of labour markets' competitiveness and factors affecting it. The total of works is planned for four years.A practical objective of the transfer of knowledge is to raise potential of knowledge and skills of the project participants and to employ the project results for increasing competitiveness of labour markets of particular European countries and their entities. The objective will be achieved through developing recommendations tailored to the needs of labour market policy, developing and implementing programmes for human capital development (great attention will be paid to the segment of young people), initiating and/or expanding cooperation with labour market institutions and business as well as creating a training centre.A significant element of the project will be common statistical research conducted by all partners the main task of which will be estimation of attitudes and behaviour of participants of European labour markets. The transfer of know