RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Multilingualism and Sustainability in Education in Amazon Trapezium'.

assistant: **Concept**

MultiSEAT is a timely, participatory research project aiming to expand the frontiers of multilingualism toward socio-ecological and environmental research to contribute to education for nature protection and sustainability. Focusing on an indigenous multi-ethnic and multilingual school in Leticia (Amazon Trapezium), the project has three research objectives: 1. Design and implement multilingually a community-based participatory methodology allowing the collection of socio-ecological and ethnographic interactional data about food supply systems (FSS), deforestation (DEF), and ecotourism (ECOT); 02. Provide insights into the ideological stances (perceptions, attitudes, beliefs, and representations) that the school community and their families have on these socio-ecological issues; and 03. Design a pilot of three research-based Multilingual, Inclusive Teaching Sequences (MITS) to tackle FSS, DEF, and ECOT within the indigenous school. To achieve these aims, MultiSEAT will empower young people from the school through participatory research, engaging them in collecting quantitative and qualitative socio-ecological and ethnographic data. Analysing indigenous perceptions of environmental issues will provide insights into the complex relations between people, language, and nature. Also, by considering language as a plurilingual praxis in the design of the MITS, we will focus on what people do and can achieve with their multilingual resources as eco-linguistic capital. At project end, the scientific community will have an empirically based, comprehensive understanding of how the triangle ‘people-language-nature’ works. We will also provide expertise and guidance to non-indigenous local and global communities, policymakers, SMEs interested in bioeconomy, teachers, private/public
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'PEMFC system and low-grade bioethanol processor unit development for back-up and off-grid power applications' (PEMBEYOND).

assistant: **Concept**

In this project a cost-competitive, energy-efficient and durable integrated PEMFC based power system operating on low-grade (crude) bioethanol will be developed for back-up and off-grid power generation. Back-up and off-grid power is one of the strongest early markets for fuel cell technology today. Wireless communication systems are rapidly expanding globally, and the need for reliable, cost-competitive and environmentally sustainable back-up and off-grid power is growing, especially in developing countries. Cost-competitive PEMFC power system compatible with crude bioethanol would allow direct use of easily transported and stored, locally produced sustainable and low-emission fuel also in developing countries, further adding value and increasing the number of potential applications and end-users for fuel cell and hydrogen technology. The PEMBeyond system will basically consist of the following functions integrated as a one complete system: a) Reforming of crude bioethanol, b) H2 purification, c) Power generation in PEMFC system. Optimized overall system design combined to use of improved system components and control strategies will lead to improvements in cost, efficiency and durability throughout the complete system. Latest automotive reformate compatible PEMFC stacks will be used, possessing high potential to reducing stack manufacturing costs. On top of this, the stacks as a part of a low-grade H2 compatible fuel cell system design will allow both FC system simplifications (e.g. no cathode humidifier needed) and complete system simplifications (e.g. higher CO ppm and lower H2% allowed) leading to decreased cost. Optimizing the target H2 quality used will be an important task with the regard to overall system cost, efficiency and durability. An extensive techno-eco
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Chemical synthesis of d-galactofuranosyl species providing new avenues for drug design in the treatment of chagas' disease' in the context of a Fourth Framework call.

assistant: **Objectives**

Research objectives and content D-Galactofuranosyl residues occur in saccharides of glycocongugates found in parasites, such as those causing Chagas' Disease, but are not present in mammalian glycoconjugates. Inhibition of D-galactofuranose biosynthesis may therefore provide new therapeutic agents for the treatment of such diseases. The synthesis of a disaccharide containing D-galactofuranose and its stable C-disaccharide analogue will be developed. The key synthetic step will utilise a tethered radical coupling of two monosaccharides as developed by Sinay and allow stereoselective formation of the interglycosidic C-C linkage. These disaccharides will be tested as direct inhibitors of the biosynthesis of D-galactofuranose, but will also be attached to a carrier protein and used to raise specific antibodies against Chagas' Disease. Another aspect of the programme will focus on the synthesis of a stable C-linked analogue of UDP-galactofuranose, via a short series of known transformations This C-UDP-galactofuranose should directly inhibit the enzyme UDP-galactopyranose mutase, which has recently been studied by GlaxoWellcome and shown to be of central importance in the biosynthesis of galactofuranose. Training content (objective, benefit and expected impact) This project will provide: new experience in techniques of biochemistry (immunology and enzymology), an extended knowledge of carbohydrate chemistry and develop new practical skills in a broad range of modern synthetic methods. Links with industry / industrial relevance (22) Access to new therapeutic agents and a deeper understanding of galactofuranose biosynthesis should be of interest to GlaxoWellcome, given their recent studies on the mutase enzyme.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Synthetic programmable artificial condensates for enzymatic reactions'.

assistant: **Concept**

Cells contain numerous membraneless organelles, also called biomolecular condensates referring to the liquid-like properties of these condensate droplets. Intrinsically disordered proteins enrich these condensates, and the presence of enzymes makes these condensates interesting reaction crucibles. In this project called Synthetic Programmable Artificial Condensates for Enzymatic Reactions (SPACER), I propose to design such organelle that can boost an enzymatic cascade both in vitro and in vivo. For this, a synthetic condensate scaffold protein will be used inspired by a consensus repetitive sequence of resillin. Such a model offers to twitch the protein length and material properties. Using the leading technology of the lab in coiled-coil sequences, the aim is to design specific recruitment of enzymes to the scaffold using hetero-dimeric coiled coils with high affinity. These fundamental building blocks will offer a large but still manageable variety of designs to explore conditions where enzymatic activity could be boosted. Aiming to further improve this system by designing it in such a way that our synthetic condensates function in cells, it could open up doors for the production of synthetic molecules that are currently challenging to produce in cells such as yeast and e.coli.


**Keywords:** Enzymes, biomolecular condensates, synthetic biology
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'INteractive CHarging' to be submitted under Horizon 2020.

assistant: **Abstract**

The INteractive Charging (INCH) project aims to commercialise a price-performance optimised smart AC charging station for plug-in electric vehicles (PEVs). It will be designed primarily for home use and use in semi-private areas where several PEVs are charging at the same time. The device will support smart charging of PEVs by offering advanced features not yet available on the market: remote interactive charging power management, real-time communication with external actors, advanced power management, different connectivity options, clustering of charging stations in the same area, precise metering of energy consumption within the charging station and support for latest charging protocols. The INCH project will present an enabling technology for the integration of PEV charging into the European smart grids and for the provision of new services in electromobility.There are two main categories of users that will benefit from INCH: end users who use the PEV charging station and other electromobility actors (service providers, PEV supply equipment operators, DSOs, energy providers, VPP operators) who can offer new services to these end users. End users will benefit from easily charging a PEV on the existing installation without worrying about potential outages, thanks to built-in flexible power management. Other electromobility stakeholders will be able to offer new added value services based on controllability and new data coming from smart charging stations.The proposed feasibility assessment will produce a study which will assess the technical and commercial feasibility of INCH by identifying relevant use cases, analysing user needs, defining the corresponding new functionalities, and researching the HW and SW required for the support of these new functionalities. Econo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'The fifth annual European Security Research Conference' (SRC10) targeting Seventh Framework.

assistant: **Abstract**

Since the beginning of the Seventh Framework Programme, Security is a new theme within the programme. Following the recommendations of the Commission’s European Security Research Advisory Board (ESRAB).The Directorate-General Enterprise and Industry co funds yearly the organisation of a Security Research Conference (SRC) which takes place in the country responsible for the Presidency of the EU, during the second half of the year.In 2010 the fifth edition of the SRC will be organized by the Belgian Federal Science Policy Office, and is scheduled from 22 to 24 September 2010 in Ostend.SRC10 will address different objectives and target groups from all European Member and Associated States as well as Third Countries. The event is expected to bring together +-1000 representatives from Research, Industry, European institutions, public authorities and other stakeholders with an interest in the security of Europe’s citizens.SRC10 will build upon the momentum of the Lisbon Treaty, creating new opportunities in the field of security. The event will have two focuses: a political one and a second focus on ‘delivery’ in the sense of new products and services by matching demand and supply. SRC10 will also communicate the results of FP7-research as well as inform on the upcoming calls.SRC10 will thus serve as a platform for exchange of ideas, potential cooperation and reconcilement of future activities on European and global level in the field of security research, technology and innovation. It will feed the long term thinking (horizon 2020).
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Mapping Out Shark’s Alternative to bone; the Innovation of calcified Cartilage.'.

assistant: **Innovation**

Shark’s and their relatives are distinctly unique compared to other vertebrates (including humans); they have an internal skeleton made entirely out of cartilage. It was presumed that cartilage was the ancestral condition among vertebrates based on the assumption that evolution would be driven toward the increased complexity of bone. However, recent fossil evidence disproves this assumption and reveals that the skeletal mineralisation shown in sharks (calcified cartilage) is an evolutionary innovation. Our understanding of calcified cartilage in sharks greatly lags behind that of the hard tissues in other vertebrates. Thus, the mechanisms behind cartilage calcification, how or whether this relates to bone, and our overall understanding of how hard tissues evolved in vertebrates is impacted. In this project, I will address this knowledge gap by examining the 3D histology of calcified cartilage in a wide range of both living and fossil sharks, using cutting-edge scanning methods. This holistic approach will cover 400 million years of cartilage evolution in sharks. The results of this project will be of importance across multiple scientific fields: advancing our understanding of the evolution of hard tissues in vertebrates, detailed 3D information on structural properties of calcified cartilage relevant to material engineering, and insight into calcification mechanisms relevant to medical research on cartilage disorders in humans. Naturalis is the perfect setting to conduct this research due to the vast collection of preserved sharks available for study, expertise in hard tissue histology, and active collaborations with medical researchers on cartilage disorders. It also offers a valuable platform for public outreach and skills training, such as in management and science c
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Smart Proxy Models for Reservoir Simulation', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Despite the progress in renewable energies, oil and gas remain the primary source of energy. Recovery from hydrocarbon reservoirs is subjected to three steps: primary, secondary and tertiary. The primary step results from the intrinsic reservoir energy; the second stage usually consists of injection of water or gas to support the pressure; and the third stage is the process of extracting the oil that cannot be recovered during the previous stages, by injecting miscible gas, thermal and chemicals. To assess the performance of implemented methods during the recovery steps, reservoir simulations are usually performed. However, these traditional simulations are known to be time-consuming, and significant number of runs is required to achieve optimal results. This project will use a combination of advanced methods including optimization, statistics and data-driven techniques, to develop a novel strategy for establishing user-friendly smart proxy models which aim at reducing significantly the run-time in reservoir simulation tasks. The project will be performed at four levels: the physical and numerical aspects of the recovery methods, sampling strategies to select runs for the proxy, learning techniques to build the proxy, and their application for optimizing recovery plans. The project has ultimate multidisciplinary aspects, including reservoir engineering, data science and environment (as CO2 storage is included in the project). The project will be carried out by the experienced researcher who worked during his PhD on the application of data-driven techniques for resolving petroleum engineering problems. The experienced researcher will collaborate with supervisors with a strong background in reservoir simulation and optimization. The transfer of knowledge from the project
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Dual action Nanoparticles using MicroAlgae extracts for chronic ulcers' to be submitted under Horizon 2020.

assistant: **Abstract**

Chronic ulcers are a major cause of morbidity and mortality with increasing prevalence. Ulcer healing is the ultimate therapeutic goal. Control of reactive oxygen species (ROS) and infection prevention are key factors to minimize inflammation and tissue damage in the healing process. The aim of this work is to take advantage of two remarkable properties of the green microalgae C. zofingiensis - the production of the highly antioxidative astaxanthin and a large amount of antibacterial fatty acids (FA) – and to combine them in a new therapeutic lipid nanoparticle for ulcer therapy (Figure 1). Thereby the project increases the pharmaceutical availability of the hydrophobic drug astaxanthin, circumvents its low bioavaliabality and chemical stability, all limiting its pharmaceutical significance until today. Nanoparticles will be characterized for their physical–chemical properties, cytotoxicity, in vitro proliferation enhancement, and wound healing properties toward normal human cells. Antioxidant activity of Dual-NanoMAE on 2D and 3D cell culture models will be monitored with FLIM-ROX, a sophisticated and sensitive technique developed by Prof. Dr. Ulrike Alexiev. Antimicrobial activity of nanoparticles will be evaluated against two reference biofilm forming bacterial strains, Staphylococcus aureus and Pseudomonas aeruginosa. Finally, the capability of Dual-NanoMAE to promote ulcer healing will be evaluated on a biofilm infected ulcer model based on human cells.


**Keywords:** Nanoparticles, chronic ulcers, oxidative stress, microalgae extract
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Lightweight, Cost-effective Composite and Green Bipropellant System for Space Transportation Applications' (GREENLAM) under Horizon Europe.

assistant: **Objectives**

Engineering novel materials and their design optimization using simulation-based tools enable the development of lightweight and sturdy thrusters. In Europe, the development of high-temperature-resistant structural materials for space transportation has gained momentum over the years. This has led to the increased usage of ceramic matrix composite over conventional metal alloys in aerospace applications. Most of the reported works focus on manufacturing cost-effective and lightweight composites, whereas the thermally stable nature of composites has not been fully explored. The Green Charter and European Green Deal promote low-emission forms of transport and emphasize developing sustainable and renewable forms of energy. The adoption of green fuels offers advantages in terms of total life cycle cost reduction, contributing to cheaper space transportation, and environmental impact reduction. Contemporary research innovations have expanded the development of ""green propellants"" for spacecraft in diverse space applications on a global level, primarily for eco-innovation and safety considerations. Studies with ammonium dinitramide, hydrazinium nitroformate with methanol, and ethanol-water are still in the nascent phase whereas H2O2 is delivering state-of-the-art performance to replace conventional hydrazine. This project aims to explore the possibility of developing a 1-100N class thruster made of thermally stable composite (carbon-ceramic) and green bipropellant (H2O2-Kerosene) system for the upper stage to reduce the overall weight, life cycle cost, and environmental impacts without compromising on the performance parameters. This will be researched through a comprehensive blend of multi-physics-based numerical modeling and analysis to generate a highly reliable design a