RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Spin-selective chiral nano-cages for molecular spintronics' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Conventional electronics employs the electron’s charge to process information. An alternative route is to utilise its spin instead, promising for realising equivalent devices that operate far more energy-efficiently, but also paving the way for entirely new applications like non-volatile memory or quantum computing. Previous attempts to realise such spintronics platforms were based on inorganic magnetic materials, often requiring very low temperatures and highest material purities that involve energy-extensive fabrication processes. Within this highly interdisciplinary project, I will explore an entirely different avenue towards spin-control which is based on the concept of chirality in novel molecular self-assemblies. Together with experts in synthetic chemistry, I have designed supramolecular cages that are chiral and can also encapsulate smaller molecules inside. Upon excitation with light, an electron can be transferred from the host to the guest, and with it the desired spin based on the chosen handedness of the molecules. This enables spin storage or switching and thus to encode information. To this end, I will combine time-resolved optical and electron spectroscopy to unravel the mechanism of chirality-induced spin-selectivity in such supramolecular structures, and then employ it for spin-dependent charge transfer from host to guest, tunable through spin-orbit coupling of the chosen building blocks. As such, I will exploit the versatility of a chemical bottom-up approach combined with light-matter interactions for the first time in chiral supramolecular nanostructures for unprecedented optical spin control, dictated by molecular design. This research will open up the path to molecular spintronics applications like memory storage, sensors or logic devices for quan
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Multiscale study of the interactions between corona viruses of various pathogenicity and cell membrane components in the early stages of virus entry' under Horizon 2020.

assistant: **Concept**

Coronaviruses (CoV) have been responsible for several severe viral outbreaks culminating in the current global pandemic. However, some viruses of this family are widespread and only cause mild conditions, like the common cold. The origin of the significant variation in the severity of the CoV-related diseases is still poorly understood. Recent studies have suggested that the strength of the interaction between the virus and the cell surface during the early stages of virus entry could play an important role. CoVs attachment to the plasma membrane is mediated by the specific interaction between the viral spike glycoprotein (CoV-S) and receptors found on the cell surface. In addition, several CoVs have been shown to interact with the cellular glycocalyx during the early attachment to the cell surface. In this proposal, I describe the study of the early entry mechanism of CoV-SARS, CoV-SARS2, and hCoV-NL63 which all target the same cellular receptor, angiotensin-converting enzyme 2, while strongly varying in their pathogenicity. The study focuses on the dynamics, kinetics and strength of the interaction of these viruses with the cell surface. It employs an incremental approach, from the study of the bond between individual CoV-S and single membrane components to multivalent interactions between the virion and the cell surface. A wide array of biophysical (e.g. single-particle tracking, and optical tweezer) and biological (e.g. viral pseudotypes) techniques are used, combining the host’s and my expertise. This multidisciplinary project will result in a unique and comprehensive characterisation of the interactions taking place during CoV-entry, it will elucidate the difference between viral species, and it will give insights into the origin of the observed differences in pat
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Development of antimicrobial peptides as novel anti-infective drugs' goes beyond current state-of-the-art under Fifth Framework.

assistant: **Innovation**

The rapid spread of antibiotic resistance requires innovative anti-infective drugs and strategies. The PANAD concept proposes to develop potent antimicrobialpeptides (Amps) to the preclinical stage of investigation. Natural and designed Amps will first be extensively screened in vitro against clinical isolates of pathogens and selected for subsequent testing in animal disease models. Screens will include combinations of Amps with conventional antibiotics. Amps with sufficient potency will be selected for simultaneous knowledge-based design andrandom-mutagenesis to increase performance. Improved Amps will re-enter in vitrotesting to advance the optimisation process. Novel technology for large-scale, cost-effective bio production of Amps will be developed.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Using déjà vu to better understand spontaneous retrieval in human memory' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

The project focuses on a new theoretical view that I recently published together with my Host supervisor. According to our continuum hypothesis, two spontaneous phenomena, déjà vu and involuntary autobiographical memories, although studied separately, are actually a result of the same underlying processes. This novel theoretical view may transform the current understanding of memory retrieval processes and is in urgent need for systematic empirical investigation to develop a data-based theoretical framework for a broad range of spontaneous cognitions. The project creates a crosstalk between currently separate areas of research in which I (an autobiographical memory specialist in experimental psychology) join forces with my Host supervisor (an expert in déjà vu, metacognition and neuropsychology) to advance theoretical models of autobiographical memory retrieval. To this end, within the project I will undertake advanced training in déjà vu methods, metacognition, single-case study methods in neuropsychology and transdisciplinary training on the brain and cognition. This will be then used in planned empirical studies aimed at (1) testing the novel theoretical approach with empirical evidence and (2) further advancing theory of autobiographical memory, déjà vu and spontaneous cognitions. While the project is expected to significantly contribute to the research area, it will also significantly advance my professional research career by providing me with new skills, knowledge, experience in new for me area of research, and to let me build up a long-lasting network of collaborators.


**Keywords:** autobiographical memory, déjà vu, involuntary memories,  involuntary cognitions,  retrieval processes,  spontaneous cognition
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Marranism and Western-European Modernity'.

assistant: **Innovation**

The project „Marranism and Western-European Modernity ” (EuMAR) has a particular approach to European history in modern times analyzing the mode of Jewish existence within this frame. The methodology is innovative and makes use of an exceptional reading of the issue. It is about the specific application of the concept of the ""Marrano"", the secret Jew. The construction of a European, trans-national Jewish identity, especially a secular identity, becomes evident. Moreover, a complex texture of “multiple modernities” (Shmuel N. Eisenstadt) within the very core of Western modernity is recognizable trough the prism of a Marrano paradigm. The Marrano does not represent something alien to European culture – and religious traditions – but is commonly assumed to be “the Other within” (Yirmiyahu Yovel) this culture. The thesis of the project EuMAR is that the Marrano is a central feature at the origin of European multicultural complexities, complexities which were augmented in the so-called post-emancipation period (after 1789). Furthermore, the backbone of the project EuMAR is that it delves into history, in particular the history of the Haskalah (Jewish Enlightenment), i.e. cultural Enlightenment and Europeanisation, as well as its reception in Western Europe, mainly in France, Italy and in the German speaking countries of the Austro-Hungarian Empire at the turning point of the 19th century. This historical transnational perspective on the Haskalah and its reception is highly innovative, as this Jewish intellectual movement and its interplay with the European Enlightenment have been prevalently studied in national contexts. Haskalah’s protagonists accomplished a “secular intellectual revolution” (Shmuel Feiner) in Western and Eastern Europe, a revolution whose impact becomes
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Landscape archaeology in southern Etruria'.

assistant: **Objectives**

THE APPLICATION AND DEVELOPMENT OF NOVEL TECHNIQUES OF LANDSCAPE ARCHAEOLOGY IN SOUTHERN ETRURIA (CENTRAL ITALY). The objectives of this research project are the development and testing of new techniques of archaeological surveys (G.I.S.; LiDAR; G.P.R.) in some key-contexts of Southern Etruria (central Italy) to get new data on landscape archaeology and new tools for preservation of monuments and archaeological artefacts. The two key contexts are: the Etruscan city of Civita di Grotte di Castro and the territory of the ager faliscus between Falerii and Nepi. Both contexts were settled from the Bronze Age onwards and show dense archaeological evidence from the Prehistoric, Etruscan, Roman and Medieval phases, and it offers excellent opportunities for landscape analysis. Both areas are characterised by different land uses (forest, arable lands) which enables the use of different methodologies of survey and non-destructive analysis.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Holographic ground probing radar system' under Fourth Framework.

assistant: **Concept**

The project deals with the realisation of a holographic ground probing radar (HGPR) prototype suitable to monitor contaminated soils and able to identify, w ith high spatial resolution, the presence and the diffusion plume of non aqueou s pollutants liquids (NAPL). The HGPR will be also adapted to be applied in arc haeological prospecting. The project claims to overcome the limit of traditi onal ground probing radar that is: low spatial resolution and artefacts in resu lting images. The HPGR technique will give, in the investigation frequency band between 0.1 GHz to 1 GHz, a higher spatial resolution to the depth of some met er. The high level of the project is justified by the strategical interest i n the environmental science to deliver a new non invasive methodology for a fas t and accurate detection and monitoring of the polluted areas. The main adva ntages of the holographic radar respect to the conventional ground probing rada r technology will reflect on: a drastic reduction of the survey costs, a best estimation of the extension of the contaminated area, permitting a bet ter evaluation of the environmental risks and the soil remediation strategy. The new technology could be applied on several targets, including pipe and pip e line detection, leakage from underground tanks and for the detection of unexp loded ordnances. The main goals of the project are: to realise the prot otype of the holographic radar, to check the system performances in the en vironmental applications. The different tasks of the projects are linked on different levels: hardware device development, software development and laborat ory and in field tests of the system. The final product of the project will be a complete prototype capable to operate in field; the prototype will be read y to be f
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'European Union Contest for Young Scientists' 2018' under Horizon 2020.

assistant: **Concept**

European Union Contest for Young Scientists (EUCYS) has been organised since 1989 with the aim of promoting science and research among Europe's youth and bringing together the talented young people across Europe. The young scientists also have the chance to meet others with similar abilities and interests and to be guided by some of the most prominent scientists in Europe. This way EUCYS seeks to strengthen the efforts made in each participating country to attract young people to careers in science and technology. EUCYS has been organised in countries across Europe with the aim of promoting science and research in different countries and bringing research and young talents into spotlight in these countries. Ireland will organise EUCYS for the second time in 2018, after hosting it for the first time in 2004. Ireland also has previous experience in organising an Irish National contest for young scientists for the last 54 years, the longest running competition of its kind in Europe. The host organiser of EUCYS 2018 will be Young Scientist & Technology Exhibition Limited in close cooperation with the Irish Department for Education and Skills.EUCYS brings together excellent young researchers from 40-69 countries. During 4 days the participating projects will be interviewed by jury members and decisions about European Union prizes, special prizes and host organisation prizes will be made.


**Keywords:** European Union Contest for Young Scientists' 2018 Dublin, Ireland
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Pathway Analysis of Treatments in Healthcare' to be submitted under Horizon Europe.

assistant: **Abstract**

“What is the drug of choice for the given condition?” is the most important question raised by patients and clinicians at the point of care. The use of systematic reviews to answer this question, accompanied often with pairwise or network meta-analysis, ensures that decisions are informed by the best available evidence. However, in many healthcare areas we are moving towards the era of treatment pathways, in which not only a single treatment but a sequence of treatments can be the optimal choice for patients. Despite the important advances in methodology of evidence synthesis, treatment adaptations, such as modifying dose, switching, adding or discontinuing treatments are rarely informed by evidence. The overarching research aim of this project is to develop and test a framework for deriving the optimal treatment pathway. To this aim, I have set the following objectives: a) develop the statistical framework to compare alternative treatment pathways and b) evaluate the framework by developing methods to make it useful and applicable to clinical practice. I have devised the concept that treatment pathways can be seen as a combination of components, in which, however, sequence needs to be taken into account. As a first step, I will thus use component network meta-analysis. I will subsequently incorporate advances from clinical trials, dose-response, time-course models and prediction models, among others. I will develop PATH using as an example schizophrenia, where I will model treatment switching, increasing dose and/or adding treatment and will produce relative effects between all alternative treatment pathways. PATH will provide a much-needed methodological toolkit to healthcare practitioners, patients and policy makers, while it has the potential to have a profound impa
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Safe and Efficient Marine Transportation of Liquid Hydrogen'.

assistant: **Concept**

The overall goal of LH2CRAFT is to develop next generation, sustainable, commercially attractive, and safe long-term storage and long-distance transportation of Liquid Hydrogen (LH2) for commercial vessels (or even as fuel in certain applications). It aims at developing an innovative containment system of membrane-type for high-capacity storage (e.g., 200,000 m3) at a temperature of -253 deg C and demonstrating and validating it on a 10 ton (180 m3) prototype. It foresees the analysis of alternative conceptual designs with safety and risk assessment initiated at an early stage of the design process of the cargo containment system (CCS) exceeding currently demonstrated sizes. The design will allow LH2 storage to large dimensions, similar to those of existing LNG carriers. Special characteristics (storage tank, handling, distribution, safety, and monitoring subsystems (HDMSS) of the concepts that support up- or down-scaling will be detailed in order to prove the modularity and scalability of the proposed solution. The CCS will achieve AiP and general approval by a major classification society (three IACS members are participating). Demonstration will be done via the detailed design, construction, and testing of the reduced size prototype. LH2CRAFT will also develop a preliminary integrated ship design and carry out the corresponding cost estimation, achieving reduced boil-off rates of 0.5 % per day. A life cycle model will provide a significant tool enabling comparison between different new design or retrofit strategies while the LCA of the large carrier will evaluate the environmental impact from cradle to grave identifying also activities related to sustainability and recyclability and determining the environmental benefits. Two societal objectives will be served: socie
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Biological trace metal stress indicators for the assessment of freshwater ecosytems' (WQSTRESS), addressing dissemination and exploitation.

assistant: **Impact**

The overall objective of this project is to study the response of phytoplankton to metal species, and develop a further understanding of the relationship between trace metal speciation and biouptake processes and ensuing toxicity, including production of intracellular trace metal stress indicators (phytochelatins) and extracellular ligands released (total uronic acid and thiols) and combined effects in metal mixtures.The specific objectives of the project are: To study the relationship between metal specia tion, bioavailability and intracellular phytochelatin production in laboratory incubations using single element additions and mixtures of metals (A) and in freshwater phytoplankton through field studies in contrasting freshwater systems. To investigate the importance of phytochelatins for the acclimatisation of freshwater algae to elevated metal exposure and the involvement of phytochelatins in the interspecies differences between phytoplankton to metal stress (C). To study the relationship between trace me tal species concentrations and production of specific exudates (thiols and uronic acid) by freshwater microorganisms in laboratory and field studies (D).To investigate the usefulness of intracellular phytochelatins (E) and of trace metal complexing extrace llular ligands (F) in freshwater systems as a trace metal stress indicators tool for the WFD. Development of non-empirical definitions and links for chemical status and ecological status of freshwater ecosystems incorporates a range of different practical and theoretical concepts and requires multidisciplinary scientific expertise. The proposed work will provide sophisticated trace metal stress indicators to the WFD for water quality assessment. The project will provide a non-empirical link between metal sp eciat