RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'New combined solution to harness wave energy full renewable potential for sustainable electricity and fresh water production' to be submitted under Horizon 2020.

assistant: **Abstract**

With 96.5% of all water on Earth being on the ocean, there is a theoretical ocean wave energy potential of 2000 GW of installed capacity, which could contribute to decarbonizing the energy system, expanding the water supply through desalination and creating a new industry with export opportunities worldwide. However, this opportunity remains underexplored due to remaining technological, market, environmental and social challenges. With wave energy still in the pre-commercial development stages, the EU setting a target of 337 GW of installed wave by 2050 and a direct EU economic impact of drought events in the past 30 years estimated at a minimum of € 100BN, there is a unique opportunity for strong industrial cooperation towards the deployment of solutions to address the twin challenges of energy and fresh water shortage. Leveraging on a strong consortium vision, expertise and technologies, the W2EW project aims to deliver a world beating and first of a kind wave powered technology solution – W2EW solution – to the market. The solution relies on the innovative integration of wave energy and water desalination technologies, to produce zero-emission electricity and fresh water.The main goal of this project is to integrate the partners technologies, demonstrate the combined solution, and build the market to pave the way for broad market roll-out. Thirty-three months after project start the consortium plans to roll out the W2EW solution on off grid small-scale energy and water production in islands and isolated coastal communities with up to 100,000 inhabitants, which corresponds to a potential market of 22Bn EUR for electricity and 6Bn EUR for freshwater. After 2025 we intend to extend the customer base of the W2EW solution to the large-scale utilities for production of ren
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'BIO: Banana IN and OUT - engineering resistance against Panama disease in banana' under Horizon 2020.

assistant: **Concept**

Panama disease is a devastating disease of banana  caused by the fungus Fusarium oxysporum f.sp. cubense. A new race called tropical race 4 (TR4) is estimated to threaten >80% of the world’s bananas and can cause up to 100% yield loss. The disease is detrimental to global banana production, but also for small-holder farmers especially in Africa, because Panama disease also affects plantain cultivars that provide food for approximately 400 million people. In the 1950s, Panama Disease almost wiped out commercial banana cultivation in Central America. Because the fungus is a vascular pathogen, there is no effective way of combating the disease with crop protection compounds. In addition, the fungus can persist in the soil for many years. Traditional breeding of banana is time consuming and has had only limited success in delivering acceptable cultivars and effective resistance. The key objectives of this proposal are to employ state-of-the-arts biotechnological solutions such as genome editing using CRISPR/Cas and high-throughput resistance gene engineering to introduce a resistance gene and deactivate a susceptibility gene in banana with the global aim of creating a banana cultivar that is resistant to Panama disease.


**Keywords:** banana, genome editing, Panama Disease, Fusarium oxysporum, resistance engineering, CRISPR, Cas, pathogen resistance, plant breeding
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Future Migration Scenarios for Europe' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

The local circumstances play a major role in the migration process, from the decision to migrate through the transit process up to the settlement in the destination countries. Nearly all international migrants move to – generally the largest – cities in destination countries, either directly, or after one or more internal moves. This is also the case across Europe, where population growth in many cities can be largely attributed to an influx of migrants. At the same time, in countries of origin the largest cities often function as gateways to destinations abroad. Many potential migrants in villages and small towns in origin countries first move to these larger cities before leaving their country. Cities, therefore, both in countries of origin and destination, are significant determinants of global migration and small-scale local knowledge on migration is necessary to avoid misleading results associated with the limitations arising from the use of global or national patterns only. FUME will therefore focus on understanding the patterns, motivations and modalities of migration at multiple geographical scales, from international through regional to the local, and on imagining possible futures. FUME will determine 1) the major factors explaining migrant movement patterns by analysing regional and local circumstances that either attract migrants or ‘push’ potential migrants to move, and 2) elaborate how possible future regional socio-demographic, economic and environmental challenges may shape future migrant movement patterns in Europe. FUME will support appropriate planning and policy-making by formulating integrated and coherent visions of how migration to and within Europe might evolve under different scenarios relating to potential demographic, socio-economic, political
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Characterization of spinal learning in a repetitive yet skilled locomotor task' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

Animals adjust movement throughout their life to adapt to a changing environment and to learn new motor skills. The underlying mechanisms have been studied for decades, almost exclusively as a function of the brain. Interestingly, however, the spinal cord adapts and learns motor sequences without the brain, using only spinal sensory feedback. Therefore, the spinal cord must contain adequate neuronal circuitry for motor learning. This project aims to characterize brain-independent mechanisms of learning that take place within the spinal cord. With a complete thoracic transection, I will functionally isolate the lumbar spinal cord from the brain and enable hindlimb locomotion on a motorized treadmill with pharmacological stimulation. Using a skilled yet repetitive locomotor paradigm, I will identify cell-types indispensable for obstacle learning through circuit manipulation. Our preliminary data indicate that mice learn to avoid obstacles and improve their performance over weeks. We will test the integrity of this performance upon specific and acute inhibition of a selected neuronal population during the behavioral task. Furthermore, using in-vivo awake eletrophysiological recordings, I will characterize circuit dynamics that underlie motor learning capacity attributed to the spinal cord while mice perform the obstacle task. This project maximizes the synergies of the host lab’s expertise, i.e., kinematic analysis, circuit dissection, and the use of high-density Neuropixel probes, and my expertise in electrophysiological recordings in mouse spinal cord. In addition to implementing an innovative system of multichannel recordings of spinal circuits in behaving mice, knowledge gained from this project will enable linking cell-type specific activity profiles in the spinal cor
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Composting of husks produced by two phase centrifugation olive oil milling plants' in the context of a Fourth Framework call.

assistant: **Objectives**

The two phases centrifugationtechnology, recently introduced in the European olive milling plants, seems to solve the problem of olive milling waste water by reducing dramatically their production, but in the meantime shifts the problem to husks, which have more water content and higher phenols concentration. The present project is aimed at selecting suitable microbial strains and testing two different composting technologies (composting pile and composting reactor, horizontal and vertical) to solve in an energetically and economically acceptable way the problem of husks disposal from the new olive milling technology, producing compost fertilizer. The expected results of the project will be a simple composting technology, supported by selected microbial strains, able to solve the problems induced by husks produced in two phases olive oil production a) husks environmental impact; b) costs for discharge of wet husks. Furthermore, the compost fertilizer production will be a contribution for the fertilizer European demand. The characteristics of the proposed technology will be: a) reduced environmental impact (emissions); b) energetic and economic suitability for SMEs. For the Husks project implementation the following steps are envisaged: 1) Husks characterization and analysis methodologies determination; 2) Preparation of starter cultures for composting: it will be done by selecting aerobic bacteria and mycetes able to degrade toxic compounds present in the husks. The selected cultures will be obtained by means of conventional techniques of enrichment cultures in laboratory. Materials particularly rich in microflora will also be tested as inoculum; 3) Addition of different wastes and biomass (wastewater from sugar-refineries, yeast production plants, wineries, breweries,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Novel Educational Model Enabling Social Innovation Skills development' (NEMESIS) targeting Horizon 2020.

assistant: **Abstract**

NEMESIS designs, develops and tests an educational model for equipping students of primary and secondary education with Social Innovation Skills, values and tools. This process will enable students to become creative social thinkers, develop entrepreneurial mindsets, and become social change makers into a world where inequality, poverty and social exclusion are still quite evident. The NEMESIS model builds on a combination of innovative pedagogies and learning models, open technologies and participatory relations and processes. It also creates bridges between the learning communities and real world social innovation experiences by creating a European wide community of social innovation practitioners eager to interact with students, facilitating interdisciplinary and intergenerational learning. To foster its potential to scale and be adopted by educational institutions around Europe, the project develops a Social Innovation Open Learning Platform to grant access to the specific educational model and resources to all with emphasis on those from disadvantaged environments. This platform also facilitates the creation of a Community of Practice of teachers, school leaders and relevant stakeholders willing to break silos, engage in dialogue, drive organizational change and experience the value of the NEMESIS educational model. NEMESIS will be piloted in Greece, Spain, UK, France and Portugal engaging stakeholders into co-creation of educational resources, collective learning through the development of projects and digital storytelling as well as into online learning and knowledge sharing communities of peers. In that way, the project builds a contemporary educational model that will act as a catalyst in innovative skills based education in Europe that is expected to improve c
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Understanding Nitrous Oxide Production from The Mainstream Partial Nitritation and Anammox Process'.

assistant: **Concept**

Sustainable nitrogen removal from wastewater is of increasing significance in the future, aiming to achieve savings of energy consumption and operational cost as well as minimized emission of greenhouse gases. Under such a context, the proposal of N2OPNA is developed to give first insights into nitrous oxide (N2O) production, a potent greenhouse gas, from the mainstream partial nitritation and Anammox (PNA) process. The influencing factors such as sludge particle size, dissolved oxygen, nitrite, hydroxylamine and inorganic carbon will be investigated using enriched granular ammonia oxidizing bacteria (AOB) and Anammox bacteria. Isotopic technique will be applied to shed some light on the transformation of N2O production pathways under varying operational conditions. Based on the process and isotopic data obtained from experiments, an integrated mathematical model for predicting N2O production in PNA system with the consideration of electron transfer, energy balance and bacterial growth will be established. The findings in this proposal would be beneficial for the design and operation of full-scale wastewater treatment plant with the aim of N2O mitigation.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Mechanistic Understanding of Heterogenised Hydrogen Evolution Catalysts Through Vibrational Spectroelectrochemistry' in the context of a Horizon 2020 call.

assistant: **Objectives**

Hydrogen (H2) will play a central role in the future global energy economy. It is therefore of utmost importance to develop economic routes for the production of H2 to make it more attractive as energy carrier medium in the future. Particularly, Co and Ni based compounds have gained attention for molecular H2 catalysis lately. Co glyoxime and pentapyridine coordinative complexes as well as Ni phosphine compounds are promising candidates exhibiting high catalytic activity in both electro- and light driven H2 catalysis in water. Nevertheless, for technological application the catalysts have to be immobilized on electrode surfaces. The adsorption strongly alters the catalytic reactions, which is still not clearly understood. To investigate the adsorbed catalysts, advanced spectroscopic methods are required that are able to provide sensitive information on the catalytic reaction at a molecular level. The aim of this proposed research is to investigate the heterogeneous catalytic reaction mechanism of Co and Ni mediated catalysis using an innovative combination of potential controlled confocal resonance Raman and ATR FT infrared absorption spectroscopy assisted by electrocatalytic methods and DFT calculations. For this, the three mentioned types of catalysts will be adsorbed on metal oxide surfaces and their catalytic reactions spectroelectrochemically and electrochemically investigated. Special emphasis is led on the role of heterogeneous electron and proton transfer steps on the overall heterogeneous catalytic activity compared to the homogeneous case. Through variation of the electrode material, the modulating material/catalyst interaction is aimed to be investigated in detail. In the outcome, the results will afford a comprehensive picture of the mechanism of metal catal
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'European confernce on advanced food technologies' (EUROTECH) under Fifth Framework.

assistant: **Objectives**

A European Conference on Advanced Technologies will be organized to optimise the knowledge gained within the Union in the field of advanced food technologies. This utilisation and integration of research results from the 4th and 5th framework for the conference and for 2 brokerage events will be the essential part of the project. It is the goal of the conference to summarize and critically discuss European research on advanced technologies and to contribute to the improvement of exchange among scientists, producers, consumer and legislators. In addition, post conference dissemination and networking activities will be carried out.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Distributed Acoustic Sensing for Cable Monitoring and Surveying for Offshore Wind Farms providing movement, depth, surface disruption and free-span readings' (2014-2020).

assistant: **Innovation**

The Cable Sentry project will provide sensitive, real-time subsea high voltage (HV) cable monitoring to the offshore wind farm industry. By coupling the fibre optic cable to the HV cable faults can be easily identified and pre-located from acoustic signals. With 90 wind farms in development across Europe with 20000 km of subsea cabling by 2020, a daily offline cost to the energy companies of €300,000 and an increasing fault occurrence rate of up to 5-8 faults per 1000 km per year in early wind farm lifetime Cable Sentry has great potential. Our prototype has been proven to provide a 50-60% time and cost saving on fault ID and location when trialled. In addition, our system does not require seabed installation and can cover cables up to 120 km in length meeting the trend for the increasing distance to shore. Cable Sentry provides value addedfunctionality as it is able to locate and measure free-span, indicate burial depth and wave height useful for cable surveying and condition monitoring. We are seeking funding for formation of a detailed business plan to demonstrate our comprehensive strategy to move our product from TRL6 to TRL8 within a Phase 2 project. We will develop a strong sales and marketing plan that will allow us to meet the growth increase anticipated due to our holding sole European distribution rights for Cable Sentry. Phase 2 work will include large-scale pilot trials for data collection and analysis to tune our algorithms to cover all potential fault types and cable positioning possibilities. Cable Sentry will enable ElectricityDistribution Services Ltd (EDS) to achieve our vision to become the leading HV asset management company for offshore wind farms in Europe. We are looking to provide real time cable fault location and maintenance, asset surveying a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Understanding and targeting cancer persister cells' to be submitted under Horizon Europe.

assistant: **Abstract**

Despite tremendous progress in cancer therapy, many patients still succumb to the disease following an initial successful response to treatment. In addition to the long-appreciated contribution of genetically mutated cells to disease recurrence, persister cells, a rare subpopulation of cells that evade therapy in the absence of any known resistance-mediating mutation, have recently emerged as orthogonal drivers of therapy failure. While there has been much progress in targeting genetic resistance, the paucity of molecular tools that can capture persister traits, as well as the lack of a robust methodological framework for their study have significantly hampered our understanding and ability to target persister cells. Nevertheless, recent breakthroughs in molecular profiling techniques, as well as growing access to human residual disease clinical samples, now provide the opportunity to uncover the molecular underpinnings of this crucial cellular state. In this project, I propose to combine state-of-the-art single-cell lineage tracing techniques with functional approaches to (1) identify the determinants that control the ability of persister cells to escape therapy-induced senescence; (2) elucidate the cellular processes that govern the duration of persister drug-induced arrest; (3) investigate how epigenetic memory shapes persisters response to subsequent cycles of therapy. CancerPersisters will establish the tools that are needed in order to study key persister traits and further our understanding of this important cancer phenotype. Successful completion of this project may instruct the development of new classes of cancer drugs that can resensitize patients to subsequent cycles of therapy by erasing cellular memory and increase progression-free survival by modulating t