RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Functional analysis of osmo-sensitive signalling processes regulating the metabolic response to environmental stress' (2007-2013).

assistant: **Innovation**

Plants use light energy, carbon dioxide, and water to produce monosaccharides - the building blocks of the polysaccharides forming plant cell walls. Plant cell walls represent the first line of defence against environmental stress while representing the bulk of the biomass used for bioenergy production. Their composition and structure influences both efficiency of bioenergy production and resistance of food crops to biotic / abiotic stress. The plant cell wall integrity maintenance mechanism monitors the functional integrity of the wall and initiates changes in cell wall structure / composition and metabolic changes in response to cell wall damage (CWD) to maintain functional integrity of the cell wall. The aim of the proposed research is to dissect the mode of action of the mechanism coordinating cell wall integrity maintenance with primary metabolism in Arabidopsis thaliana. Previous work in the host lab has implicated sugar-based signalling and turgor-sensitive processes in the response to CWD. The host lab has developed FRET-based nanosensors targeted to different cellular compartments for in vivo soluble sugar detection. These sensors will enable determination of the effects of CWD and turgor manipulation on intracellular soluble sugar distribution with subcellular resolution. In addition, a phospho-proteomics approach will be employed to identify and functionally characterise novel proteins required for mediating the response to CWD and turgor induced metabolic changes. Candidate proteins identified in the screen will be validated by biochemical assays and phenotypic characterisation of candidate gene knockouts. The results of this project will provide novel insights into the cell wall integrity maintenance mechanism that could lead to improved food crop performan
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Non-Commutative Geometry, Gauge Theories and Higher Yang-Mills Theories with Nonabelian 2-Form Gauge Potential' (NCGGTH), addressing dissemination and exploitation.

assistant: **Impact**

This is a study of gravity as a gauge theory on noncommutative spaces. Seiberg-Witten map, deformation quantization, random matrix models are some of the noncommutative geometry methods used. Noncommutative geometry techniques are also applied to deform a belian gauge theories with 2-form gauge potential. Global aspects of these theories are described by bundle gerbes (these are a higher version of line bundles) . Noncommutative bundle gerbes are then applied to the noncommutative description of D-branes. Nonabelian bundle gerbes and their associated nonabelian gauge theories with 2-form gauge potential are also investigated (with recently developed differential geometry methods). Also this theory is then applied to study branes. Professional reintegration will be attained through: strict research collaboration, supervising activity (graduate students), teaching activity, co-organization of workshops, creation of new (international) research collaborations. There is a strategy for successful stable reintegra tion of the researcher in the host institution. The researcher returns to his region of origin.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Working life changes and training of older workers' under Fourth Framework.

assistant: **Concept**

From the points of view of education, training and learning among older (45+) workers the research project Older Workers and a Changing Working Life focuses on individual and organizational effects, needs and opportunities emanating from the intersection of two trends in society: The ageing of populations and changes in working life. The development and learning of old and young workers are studied within the context of work organisations. With this focus the issues of knowledge, skills, learning, values, attitudes and behaviour of the ageing workforce will be examined. Case studies of good practice in educational and training interventions in different work places will be evaluated. The key objectives of the research project are: 1. To investigate the extent to which the knowledge, skills, experience, and attitudes of older workers can be recognised, valued and utilized in work and learning situations. 2. To investigate the ways in which older workers learn within work settings. 3. To investigate the extent to which human resource development practice and educational interventions involving older workers can facilitate lifelong learning and productivity. 4. To investigate the ways in which the diversity of the workforce in terms of age and acquisition of knowledge, skills, experience and attitudes can contribute to the development of learning organizations in the work context and, more generally, to the creation of the learning society. 5. To demonstrate through case study and comparative analysis of good practice in different countries the ways in which the above objectives can contribute to the flexibility and productivity of the European older workforce and to social cohesion generally. To achieve these objectives, cases of work organizations representing different
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'The role of learning in governance practices for sustainable urban development: the case of Hong Kong special administrative region' demonstrating excellence, impact and implementation quality for a Sixth Framework call.

assistant: **Abstract**

The effectiveness governance has been a central theme for scholarly research and policy debates on urban development throughout the 1990s. Its urgency illustrated by the magnitude of the current and predicted population growth in urban areas around the world, and of related environmental and health problems and costs. These trends are especially acute in Hong Kong Special Administrative Region (SAR) and Mainland China, but governance remains under-researched here.This project focuses on learning as a fundamental crosscutting issue of governance theory and practice. The research objectives are to explore the nature and causes of selected governance problems, and to investigate the potential - and the limitations - of rational, social and organisational forms of learning as means of strengthening the governance capacity of organisations involved in urban planning. The aim is to make a fundamental contribution to the development of new understandings of governance for sustainable urban planning, informed by an inquiry that draws on recent research in different branches of the social sciences and on the collection of detailed primary data.The results are likely to be of considerable interest to a range of user communities. This is a 3-year investigation in collaboration with top-level universities in Hong Kong and Lisbon. The proposal and training programme have been designed to acquire new skills as well as theoretical and empirical insight through an international experience. This Fellowship application is submitted at a critical time for the researcher's career and represents a unique opportunity to build on her existing strengths, providing her with a more complete set of skills and thus the confidence to consolidate her return to academia and progress towards a diverse
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'The Agricultural Origins of Urban Civilization' to be submitted under Seventh Framework.

assistant: **Abstract**

The establishment of farming is a pivotal moment in human history, setting the stage for the emergence of class-based society and urbanization. Monolithic views of the nature and development of early agriculture, however, have prevented clear understanding of how exactly farming fuelled, shaped and sustained the emergence of complex societies. A breakthrough in archaeological approach is needed to determine the actual roles of farming in the emergence of social complexity. The methodology required must push beyond conventional interpretation of the most direct farming evidence – archaeobotanical remains of crops and associated arable weeds – to reconstruct not only what crops were grown, but also how, where and why farming was practised. Addressing these related aspects, in contexts ranging from early agricultural villages to some of the world’s earliest cities, would provide the key to unraveling the contribution of farming to the development of lasting social inequalities. The research proposed here takes a new interdisciplinary approach combining archaeobotany, plant stable isotope chemistry and functional plant ecology, building on groundwork laid in previous research by the applicant. These approaches will be applied to two relatively well researched areas, western Asia and Europe, where a series of sites that chart multiple pathways to early complex societies offer rich plant and other bioarchaeological assemblages. The proposed project will set a wholly new standard of insight into early farming and its relationship with early civilization, facilitating similar approaches in other parts of the world and the construction of comparative perspectives on the global significance of early agriculture in social development.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'European Network of Bipolar Research Expert Centres' in the context of a Seventh Framework call.

assistant: **Objectives**

Bipolar (BP) disorder is characterized by recurrent manic and depressive episodes, affecting more than 1% of the EU population. Delay in the diagnosis (based only on clinical features), uncertainties in the definition of episodes and on the treatment strategy best adapted to each patient lead to devastating socio-economic, professional and family consequences that be reverted by optimized diagnostic and treatment procedures. ENBREC is designed to build an EU-wide network of expert centres specialising in research and care on BP disorder, in order to integrate research efforts on the mechanism of disease, and on optimized diagnostic and treatment. Common tools and practice, training and information will help structuring the EU BP research community and translate research outcome into healthcare, as listed in the work packages: WP1: Management of the project WP2: Developing common tools for diagnosis and multinational cohort follow-up WP3: Developing common tools for cognitive assessment WP4: Assessment of common biomarkers and genetic markers  WP5: Development of standards for imaging WP6: Treatment optimisation, definition of subgroups of responders WP7: Supporting multinational clinical research and data management WP8: Education, information, dissemination, translation of research outcomes into healthcare  WP9: Extension to new countries and within the countries The consortium currently covers networks of BP expert centres reaching the critical mass in Germany, Italy, Norway, Spain, UK, and France (representing more than 300 Millions EU citizens), and plans to extend to other EU member states. It also includes ECRIN, the FP7 infrastructure providing support to multinational clinical studies. Integration of EU research and care on BP disorder will benefit EU patients a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'The aged in home care project' goes beyond current state-of-the-art under Fifth Framework.

assistant: **Innovation**

Despite Home Care (HC) is among the fastest growing segments in the health care sector, there is no information about the characteristics of Services, patients and outcomes nor shared knowledge regarding the best models of care. This Project aims to define the characteristics of Home Care patients and Services in 11 European courtiers. Baseline characteristics of both patients and Services and year follow-up data will be collected by trained personnel and centrally scored in a database, the Community Care Data Centre. Data will be shared among partners via Intranet connection. The analysis of the one-year clinical and functional outcomes will enable the possibility to design and propose reference model of Home Care, not available at present.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Lignocellulosic oil: novel biofuel platform for maritime transportation'.

assistant: **Objectives**

SEAFARER has the objective to further mature, demonstrate, and bring to market the next-generation bio (fuel) oil process allowing oil refineries to retrofit for 100% climate-neutral operations. Our patented technology is the first process for high-efficient sustainable biomass conversion using lignocellulose and even pure lignin as feedstock – the most abundantly available & non-edible waste biomass on Earth, yet currently to 98% unexploited. Our process is simple (one-step reaction; no catalysts), 80% energy-efficient and more than 2-times cheaper than all existing biofuel oil production methods. Our technology is thus highly scalable, able to produce lignocellulosic biofuel oil (L-BFO) that is fully miscible with all current liquid fuels – a unique feature, especially for the maritime sector, where engines found aboard large ships are adapted to more crude fuels (i.e. no refinement step needed for using our L-BFO) and where replacing (heavy & costly) engines is not an option.


**Keywords:** Maritime transport,Environmental and Green Technologies,Industrial bioengineering,Energy Economics,Circular Economy,Fuel process engineering,Clean transportation fuel,Sustainable biomass,Lignin biomass,Lignocellulosic oil,CO2  savings,Marine fuel oil,Green Deal,Bioeconomy
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'An Integrative Approach to Understanding Convergent Evolution in Ant-eating Mammals' (ConvergeAnt), addressing dissemination and exploitation.

assistant: **Impact**

Despite its widespread occurrence across the tree of life, many questions still remain unanswered concerning the fascinating phenomenon of convergent evolution. Ant-eating mammals constitute a textbook example of morphological convergence with at least five independent origins in placentals (armadillos, anteaters, aardvarks, pangolins, and aardwolves). The large extent of convergent morphological evolution, the importance of molecular convergence, and the role of the host microbiome in diet adaptation are currently gaining acceptance. However, large-scale comparative studies combining morphology, host genomics, and metagenomics of the associated microbiome are still lacking. In the ConvergeAnt project, we propose taking advantage of the unique set of convergently evolved characters associated with the ant-eating diet to investigate the molecular mechanisms underlying phenotypical adaptation. By using state-of-the art phenotyping methods based on X-ray micro-computed tomography and Illumina sequencing technologies we will combine morphometric, genomic, and metagenomic approaches to evaluate the extent of convergent evolution in the skull of myrmecophagous placentals, in their genomes, and in their associated oral and gut microbiomes. With this ambitious research proposal, we aim at providing answers to longstanding but fundamental evolutionary questions pertaining to the mechanisms of convergent evolution. The ConvergeAnt project will be the first of its kind to apply such an integrative approach to investigate the complex interplay between the mammalian genome and its associated microbiome in a classical case of adaptive convergence driven by a highly specialized diet.


**Keywords:** Molecular evolution, Morphological evolution, Development, Convergence, Microbiomes
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Symbiotic bacteria as a delivery system for Nanobodies that target the insect-parasite interplay' in the context of a Seventh Framework call.

assistant: **Objectives**

The tsetse fly (Glossina spp.) salivary gland is the final micro-environment where the Trypanosoma brucei parasites adhere and undergo a complex re-programming cycle resulting in an end stage that is re-programmed to continue its life cycle in a new mammalian host. The molecular parasite-vector communications that orchestrate this trypanosome development in tsetse fly salivary glands remain unknown mainly due to the limited availability of experimental tools for functional research.  We hypothesize that an innovative paratransgenic approach using the Sodalis glossinidius endosymbiont to deliver Nanobodies  that target the trypanosome-tsetse fly crosstalk will open a new avenue to unravel the molecular determinants of this specific parasite-vector association.  In this project I will develop an innovative Sodalis-based internal delivery system for Nanobodies to target the tsetse fly – trypanosome interplay and, as final outcome, will generate a trypanosome-resistant tsetse fly. In addition, I will explore the completely ‘unknown’ of the molecular nature of trypanosome adherence to the salivary gland epithelium. This will be addressed by a challenging proteomic-based approach on the tsetse salivary gland - trypanosome membrane complex and by the newly developed paratransgenic approach using the S. glossinidius endosymbiont as an internal delivery system for salivary gland epithelium-targeting Nanobodies. The application of this innovative concept of using pathogen-targeting Nanobodies delivered by  insect symbiotic bacteria could be extended to other vector-pathogen systems such as Anopheles gambiae – Plasmodium falciparum and Aedes aegypti – dengue virus.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Improvement of current and development of new vaccines for theileriosis and babesios of small ruminants'.

assistant: **Concept**

The proposal deals with the establishment of control measures for two major tick-borne diseases of small ruminants: theileriosis caused by Theileria lestoquardi and T. uilenbergi and babesiosis caused by Babesia ovis. The research programme aims at improving existing and producing new attenuated vaccines, designing subunit vaccines and capability building. To achieve these goals the proposal will assess parasite diversity and identify molecules associated with attenuation of parasite virulence to be included in the development of safe and efficacious live vaccines. For the design of a subunit vaccine parasite molecules will be identified and characterized involved in i) invasion of host cells ii) activation of CD4+ T cells and NK cells for the production of cytokines capable of activating macrophages for killing of the parasites and iii) activation of cytotoxic T-lymphocytes involved in killing of T. lestoquardi-infected leucocytes. For improvement of attenuated vaccines, a combination of vaccine with subunit vaccine will be examined for synergistic effects and reducing the need of a cold chain by improving storage conditions/ shelf life of vaccine will be aimed for. Groups working on Plasmodium are involved with the goal to benefit from the scientific and technological knowledge in this field and to translate it into tools and reagents for small ruminant piroplasms. Industrial expertise regarding vaccine development and delivery systems will be incorporated in the whole project. The impact of the vaccine to be produced against these emerging tick-borne diseases will be enormous, as they pose a great threat to livestock production, and a contribution will be made that will meet critical Millennium development goals: food security, food safety, poverty alleviation, anima