RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Anaerobic microbiological oxidation underpinning sustainable energy generation (MicroGen)' (MicroGen), addressing dissemination and exploitation.

assistant: **Impact**

The objective of this project is to build a strong research capability at the National University of Ireland (NUI), Galway for the study of anaerobic microbiological conversions for sustainable energy generation. There is an urgent requirement for the EU to develop sustainable energy sources, to comply with economic, environmental and strategic imperatives, including a growing energy demand, the requirement for secure energy supplies and the critical need to address pollution and climate change issues.The host institute is an active multidisciplinary research centre with an international reputation for its work in studies of anaerobic digestion microbiology, bioreactor technology, biological hydrogen production and electrochemistry. To maximise the technological benefits of the research being carried out in Galway, an expertise deficit in frontline analytical techniques and in computational modelling, which allow determination of in situ microbial activity and process chemistry and which can be applied to intensively monitored reactors/fuel cells, must be addressed.The transfer of such expertise from leading institutes will allow this multi-disciplinary research field (microbiology; bioprocess technology; micro-analytics) to be developed to its full potential. The ToK will be implemented by seconding 3 existing core personnel from Galway to 3 world-class partner institutions for high-level training, and by recruiting experienced researchers to NUI, Galway. The recruited researchers will work closely with existing core staff and trainee researchers based in Galway and will be fully integrated into existing and developing research programmes, in order to effect a successful knowledge transfer.The innovative, multidisciplinary and pan-European nature of this proposal stron
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'OPEN HOUSE - Benchmarking and mainstreaming building sustainability on the EU based on transparency and openness (open source and availability) from model to implementation'.

assistant: **Objectives**

The overall objective of OPEN HOUSE is to develop and to implement a common European transparent building assessment methodology, complementing the existing ones, for planning and constructing sustainable buildings by means of an open approach and technical platform. OPEN HOUSE will develop a transparent approach able to emerge collectively in an open way across the EU. This approach will be communicated to all stakeholders and their interaction and influence on the methodology will be assured in a democratic way. The baseline will be existing standards (both CEN/TC 350 and ISO TC59/SC17), the EPBD Directive and its national transpositions, and methodologies for assessing building sustainability at international, European and national level.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'CONVERSION OF A LIGNITE COAL-FIRED SYSTEM INTO A BIOMASS FUEL SYSTEM, PARTIALLY USING CONTAMINATED RECYCLING TIMBER IN THE WOLFEN POWER STATION' (1994-1998).

assistant: **Innovation**

Conversion of a lignite coal-fired system into a biomass fuel system as a demonstration project.Obtaining long dwell times at high combustion temperatures. Maintaining the firing heat capacity and the process parameters for the use of energy.Maximisation of power production within a combined cycle system (coupling of power and heat generation) by utilising biomass fuels.Adaptation of the firing system to a wide fuel band of biomass and recycling materials.Utilisation of the existing steam generator as well as the off-sites for energy production and conversion.Provision of energy independently of CO2 conditions.Design of a firing system with a high thermal power to comply with biomass fuels and recycling timber with a high calorific value.Choosing a high dwell time at high combustion temperatures independently of a biomass fuel.High combustion chamber end temperatures while using biomass fuels.Maintaining the high steam parameters in spite of the relatively low ash softening temperatures.No restrictions to process parameters through the fuel type, the definition of these parameters being effected purely for energetic reasons.Mixed firing of biomass fuels with contaminated residual and recycling materials.Utilisation of a flue gas cleaning system according to the waste combustion rule (17.BlmSchV) to obtain minimum emissions and for the utilisation of impregnated recycling timber.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'An augmented reality environment for the safety and the accuracy during computer assisted orthopedic surgical interventions' to be submitted under Fourth Framework.

assistant: **Abstract**

Research objectives and content The applicant will develop and test a demonstrator of a AR system. This system will help surgeons to use in a fully integrated and effective manner multidimensional data (images, 3D models, atlas, planned procedures) for the execution of accurate and safe orthopaedic surgical procedures. The reality enhancement obtained, by the system that the applicant will develop, will be basically of 'visual' type. The basic requirements of such a system are to provide a good registration of images and model (in order to achieve the right display) and to display 3D hidden organs and surgical target. To this aim the applicant will install and equip the working site with a 3D sensors system able to track the position of surgical instruments and of anatomical reference during the intervention. The applicant will develop an innovative concept based 'friendly' user interface that will enable users to control the technology in a simple, satisfying and effective manner. The interface will be fully based on a 3D interaction with the options of the interface and with the surgical environment, this approach will permit the surgeon to not move hands and sight apart from the surgical scenario when the he/she has to select an interface option. Training content (objective, benefit and expected impact) This research project aims to integrate the high qualified expertise of the applicant in the real clinical environment of the host institute offering to him an unique opportunity of training in terms of methodological approach and interaction with the specific surgical environment constraints. But above all the need of developing an effective solution to clinical problems by defining innovative systems and by integrating new technologies will assure an important condi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Client requirements definition improvement' (CREDIT) targeting Fourth Framework.

assistant: **Abstract**

To effectively meet the increase in demand for our products and services TrendSoft has recognised the need to put in place the necessary underlying structures and processes. TrendSoft is currently implementing a Quality Management System and has identified the critical area of accurate Client functional requirements definition as being a fundamental aspect of our on-going Client management and thus future success. TrendSoft recognises that improvements in this area will yield a positive benefits down-the-line throughout the remainder of the development process.This is a common concern to the software industry where the primary business objective is to meet the customers requirements in terms of product as required, within the agreed costs and timeframe.THE EXPERIMENTThe achievement of the above requires both the building of a 'Stakeholder Partnership' between ourselves, as supplier, and the Client, and, through this partnership and supported by methods and tools, an improvement of the company's ability to gather, specify and manage Client functional requirements. An appropriate method will be tailored to suit our needs. The tools would include:(a) Analyst Workbench e.g. System Architect. Used to manage and control the clients information.(b) Data Modelling e.g. ERwin. Used to model data relationships and elements.(c) Document Management. Used to manage document versions. MS Word may suffice.Vision Express are a major chain of Optical Product retailers. TrendSoft is continuing to develop the product in line with their needs and will use the 5th Phase of this project as the baseline application. TrendSoft employs 20 people, 13 of whom are involved in software development.EXPECTED IMPACT AND EXPERIENCEThe experiment is expected to yield higher productivity, shorter develop
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Selection of phage displayed peptide and antibody libraries for specific binding to human tumour vascular by panning in ex vivo perfused human tumour-bearing organs' goes beyond current state-of-the-art under Sixth Framework.

assistant: **Innovation**

The main objective of the project is to generate antibodies that specifically bind to human tumour vasculature. This will be achieved by ex vivo perfusion of surgically resected livers containing tumours, with phage display libraries. The phage display technology has already been applied successfully in in-vivo selection for tumour vasculature in mice. However, a disadvantage of this system is that while the tumour cells can be human, the vasculature is of mouse origin, and the human tumour vasculature antigens will differ.   Selection of phage displayed antibodies by perfusion of tumour-bearing organs is novel because it will give direct access to living human tumour vasculature. Using resected human liver segments, we have established a perfusion system, and demonstrated that phage are delivered to the tumour vasculature as demonstrated by immunohistochemistry.   To ensure the highest possible success rate in the perfusion-selections, we have characterised different phage display systems for display efficiency and optimised phage production protocols The selected antibodies will initially be investigated in established immunohistochemical assays, and subsequently tested for potential tumour vascular targeting using resected tumour-bearing organs in our perfusion system. The perfusion-selection of phage-display libraries described offers a unique opportunity to generate clinically relevant antibodies or peptides for anti-vascular cancer therapy and to identify important human tumour vascular antigens.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Evolution of cockPIt operations Levering on cOgnitive compuTing Services' under Horizon 2020.

assistant: **Concept**

New technologies have allowed pilots to assume more responsibilities reducing the number of some mechanic and repetitive tasks through automation. The flight deck transition to digital computer-based flight management system has shown a reduction of the workload across a variety of tasks. However, there are still several open issues that requires further research and a deeper understanding of pilot cognitive decision making process to guide next steps on aircraft control task sharing between human pilots and machines.Present project proposal will analyse the benefits of cognitive computing assistant and the challenges in key areas such as the relationship between pilot with the surrounding traffic and the aircraft state evolution considering the pressure of the operational context factors such as task responsibilities, situational awareness,  and the performance objectives of the mission among others. The dynamics of these interdependencies will be analysed by means of ML techniques identifying the different thresholds that actives a cognitive tasks which will be the baseline to elaborate new symbiosis dynamic structures to improve human-machine information sharing mechanisms. Human-in-the-mesh modelling paradigm relying on cognitive computing technologies will drive the research and innovation efforts to identify the potential changes in pilot roles and task responsibilities that will improve aircraft system reliability and performance, the pathway to automation in the flight deck to simplify the crew interaction with the systems and make tacit knowledge explicit to be accessible and usable for automated, intelligent systems.This proposal consider cockpit operations for “man-computer symbiosis” as a metaphor for designing decision support systems that enhance human cog
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Integrating chemical and biological approaches to target NAD production and signaling in cancer', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Deregulated nicotinamide adenine dinucleotide (NAD) biosynthesis and signaling underlies many aspects of carcinogenesis. NAD biosynthetic enzymes, such as nicotinamide phosphoribosyltransferase (NAMPT) and nicotinic acid phosphoribosyltransferase (NAPRT), are commonly upregulated in cancer cells, where they fuel increased metabolic demands and downstream enzymes involved in DNA repair and in the promotion of cell growth, cell motility, de-differentiation and immune escape. In addition, NAD-producing enzymes, such as NAMPT, moonlight in the extracellular space, exerting strongly pro-oncogenic, autocrine and paracrine effects. Many of these roles of NAD-producing and NAD-utilizing enzymes appear to be shared between solid and haematological cancers. Thus, agents targeting NAD production or signaling are expected to have broad applicability. INTEGRATA will: 1. develop new NAD biosynthesis and NAD/nucleotide signaling inhibitors; 2. assess pharmacology and toxicity of the new therapeutics in preclinical models; 3. achieve the proof-of-concept of activity of the newly generated agents in relevant in vivo cancer models. INTEGRATA will train 14 PhD students in an overarching, interdisciplinary training programme that will include training-by-research, joint courses of technical, scientific, and transferrable skills, active participation to public scientific events, and an intense intersectoral networking exchange plan. The INTEGRATA Consortium encompasses academic institutions, research centres, and SMEs/biotech pharma, all with proven experience in higher education and training, and geared with state-of-the-art scientific and technical expertise and infrastructures.


**Keywords:** NAD production, NAD signaling, new targets, cancer
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Training Industry in Neutron Strain Scanning' (1994-1998) targeting Fourth Framework.

assistant: **Abstract**

The complete understanding of the stresses within manufactured components and structures remains an unsolved, but important goal of engineers and metallurgists. Such an understanding would lead to stronger, lighter, longer-lasting and cheaper components. It would also enable critical decisions relating to the safe use of components or structures to be made with greater certainty. The measurement of strain (and hence stress) deep within materials has recently taken a significant step forward with the construction and development (under Brite/EuRam II - PREMIS - project no. 5129 ) of ENGIN, a dedicated pulsed neutron strain scanning (PNSS) instrument at the ISIS facility in the UK. The proposed Thematic Network plans to stimulate technological innovation through the incorporation of this new technology into industry. The Network will also promote technological co-operation and integration between European industry, research laboratories and universities in this important area of research. The Thematic Network will have three aims: to train industrial members of the network in the technique of neutron strain-scanning to co-ordinate the European research in this area and to assist in the creation of neutron strain measurement standards to publicise the technique to a wider industrial base.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Negotiating Social Inequalities in Late Prehistoric Cyprus' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

The consolidation of social inequalities, postulated to have occurred during the Bronze Age in West Asia, is of crucial importance in the rise of complex societies, yet remains poorly understood. This research project will apply an innovative mixed methods approach to datasets from late prehistoric Cyprus (4000-1700 BCE) to better investigate this key development in global history.Recent archaeological research into social inequalities has either used quantitative methods to demonstrate their emergence (Kohler et al. 2018; Basri and Lawrence 2020) or questioned their existence in early complex societies (Graeber and Wengrow 2021), leaving the question of how social inequalities were first consolidated open. To move this topic forward we need an approach that combines quantitative and qualitative analysis, to assess the significance and durability of social inequalities in prehistoric societies (Klinkenberg and Düring 2023).  Late prehistoric Cyprus provides an exceptional possibility to research this topic. Decades of research have produced rich datasets from settlements and cemeteries, that suggest clear transformations in the articulation of social inequalities. In the Chalcolithic (4000-2500 BCE) we have evidence for short-lived social inequalities, especially in house sizes. By contrast, in the Prehistoric Bronze Age (2500-1700 BCE), social inequalities appear more consolidated, for example in graves. This project will investigate social inequalities in everyday life (houses, objects, mobility, and diet), and in performed settings (burials, feasts, and figurative objects), to reconstruct how social inequalities featured in these social arenas. The aim is to both quantify evidence for social inequalities, and study how inequalities were culturally negotiated. The res
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Ventilation-based strategies to control terrorism involving chemical, biological, or radioactive (CBR) agents' will create measurable scientific, societal and economic impact aligned with Sixth Framework.

assistant: **Impact**

Ventilation-based strategies to control terrorism involving chemical, biological or radioactive (CBR) agents. Techniques for predicting health risks, for designing concepts for protection of buildings and their occupants, and for simulating accident scenarios will be reviewed and developed. Problems to be analysed by Computational Fluid Dynamics and/or experimental methods include: Detection, transport of airborne hazardous substances, confinement, or removal of such substances. Accident reports of recent terrorist attacks will be reviewed.Typical scenarios will be assessed regarding the employed methods of attack, agents used, actual evacuation success, and spread of harmful substances. Preventive measures in place at time of attack and lessons learned from each incident will be studied. Based on these findings, effective preventive measures and ventilation-based strategies will be proposed. Their effectiveness will be evaluated by computer simulation. Computational Fluid Dynamics, CFD, will be used to predict spread of harmful gases and their local concentrations as functions of time and position.Impact of toxic dose on human organism will be estimated to obtain an approximate probability for survival of building occupants or for the degree of injury. The determination of probability of escape will require accurate information on propagation speed of the toxic gas cloud as well as of movement of the persons on their escape route.