RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Ontologies of Waste: A Relational Study of How Waste Comes to Matter for Humans, Society, and Future'.

assistant: **Concept**

The future world imagined by the circular economic model is a world without waste, provided that materials and energy circulate efficiently enough through society. The project WasteMatters disrupts the waste-as-resource paradigm prevalent in the circular economy related politics, business, and scholarship alike, and examines our contemporary trashscapes beyond the idea(l) of the eternal redemption of waste. Its novel approach is to analyse the leaky realities of waste as integral to the human condition and as constitutive of society. The project explores the implications of waste throughout society and what waste does for/to us; what kind of relations, agencies, and spatiotemporal scales it assumes, prompts, enacts, and sustains; to what kind of futures society commits itself with it; and what humans become with waste. The project develops a new methodology, more-than-human ethnography, to be able to attend to the vibrant nature and active role of waste in how we live together. The research will be carried out through four sub-studies across various sites (in Sweden and Finland), which function as important nodal points in the management and circulation of wastes: households, businesses, biogas plants, waste incinerators, and a nuclear waste repository and, to attend to the multiplicity of waste, the project will focus on four kinds of waste: food waste, plastic waste, waste incineration ash, and nuclear waste. Through the research design, the project will generate ground-breaking insight into waste as both constitutive of society and as something that disturbs it. The empirical, methodological, and conceptual insights will be combined to enable a leap in theory building to develop a new relational theory of waste that pays attention to the multiple spatiotemporal scale
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'ExploRing the surface slopes Of aSteroids'.

assistant: **Concept**

Understanding the near-surface and interior structure of asteroids is required in order to model changes to the asteroid’s trajectory, as may be necessary to deflect a hazardous asteroid, and for understanding the asteroid’s response to the landing of either humans or robots on the surface. Here, I propose to investigate the surface topography of asteroids to develop a surface slope metric that can probe the near-surface and interior structure of asteroids from shape models alone. This will provide a rapid and low-cost method to understand asteroid structure from flyby data rather than the more expensive and time-consuming rendezvous mission. By measuring the surface slopes of asteroids at the same horizontal scale we can see past vastly different asteroid sizes, which will allow many asteroids to be compared to one another in an independent manner. The proposed action is broken into three parts. The first part of the action is focused on developing a slope metric on the two asteroids that have been studied in the highest detail of any asteroids but have different interior structures, Eros and Itokawa. The second part involves investigating how sub-surface structure affects surface slope in a linked geomorphic seismic shaking model where we will be able to test the physical processes that affect surface slope. Finally, in the last part of the study, we will apply the slope metric to asteroids with low-resolution shape models to probe their interior and near-surface structure.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Smart Access to Manufacturing for Systems Integration' (SMARTER-SI) targeting Horizon 2020.

assistant: **Abstract**

Over the last decade, development of Smart Systems Integration (SSI) has demonstrated tremendous benefits in terms of enabling new functionalities of diverse products contributing to enormous economic potential with annual efforts in Europe estimated at approx.10 b€. There is significant opportunity for innovative SME’s to further exploit SSI as they are ideally placed to commercialise and drive the whole product development cycle, effectively bridging the “valley of death”. Europe is in a strong position to champion its’ established RTO’s competitive research, development and production facilities and to be a World leader in transitioning product development in SSI from prototyping to manufacturing, with particular focus in the low volume high value chain domain. SMARTER-SI has a unique opportunity to capitalise on Europe’s research excellence in SSI, leverage expertise of SME’s and RTO’s and drive impact through commercial exploitation.Inspired by the Strategic Research Agenda of EPoSS, SMARTER-SI aims to develop a RTO Community Foundry Model (CFM) that will accelerate a wider deployment of SSI with greater access to design, manufacturing capabilities for prototyping, early validation and first production for SME’s to exploit in niche markets. A strategic objective is to lower entry barriers using the cooperative approach of utilising existing process steps/building blocks available at partner RTOs. This in turn will advance innovative products for SMEs in Europe. The system approach will enable these companies to reach for a higher profit margin than currently achievable with components sales. SMARTER-SI will thus facilitate a greater level of innovation and know-how that will reside within Europe and will be difficult to replicate by competitors in other regions for
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fifth Framework proposal for the project 'New approaches to treatment and control of Lassa fever and Yellow fever in West Africa'.

assistant: **Objectives**

From survivors of LF or YF, combinatorial phage-display antibody libraries will be constructed and neutralizing antibodies will be selected. Recombinant antibodies will be used for studying the molecular mechanisms of virus neutralization and will be engineered for immunotherapy. Mastomys natalensis, the principal rodent vector of Lassa virus, appears to be a morphologically indistinguishable complex of subspecies in West Africa. We will develop cytogenetic and molecular techniques to differentiate these subspecies and correlate them with their vector capacity for Lassa virus. A better understanding of the vector biology of Mastomys may lead to new ecological approaches for the Control of LF. To improve YF surveillance in Africa, new PCR strategies will be developed to detect all recently described five genotypes of YF in pooled mosquitoes.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Understanding Copper–Zinc Synergy for Carbon Dioxide Hydrogenation' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Carbon dioxide (CO2) is a greenhouse gas that is significantly contributing to climate change. In tandem with advances in sequestering carbon, beneficial uses for CO2 are of high societal importance for developing a sustainable future. One attractive use of CO2 is in its conversion to energy dense fuels (green energy vectors). One such fuel is methanol, made from CO2 via hydrogenation in conjunction with a multimetallic catalyst. The current best industrial (heterogeneous) catalyst incorporates copper and zinc-oxide nanoparticles with an alumina support. A special synergy is observed between the copper (active site) and zinc (reaction promoter), but these species and their connection is poorly defined and remains debated.This project aims to isolate proximal copper and zinc centres, the fundamental building block for the construction of critical copper–zinc interfaces, within a well-defined, and highly tuneable ligand framework. Once isolated, the binding, activation and interconversion of key intermediates along the CO2 hydrogenation pathway will be meticulously analysed.Work package 1 involves the synthesis and characterisation of a series of 12 ligands that encompass a range of stereo-electronic profiles, and subsequent isolation of CuZn complexes using these ligands. Work package 2 will use the complexes to study the activation and interconversion of key intermediates along the CO2 hydrogenation pathway to gain mechanistic understanding. Finally, work package 3 will test the most active complexes as catalysts for the direct hydrogenation of CO2 to methanol.The combination of my skills (multimetallic systems) and the host groups (mechanistic studies) make achieving the project aims realistic. The knowledge harnessed from gaining deep mechanistic understanding of the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'NeuroLF: The best small  and mobile dedicated brain PET scanner for an accessible early detection of Alzheimer’s disease' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Dementia affects around 50 M people globally (mainly over 65 years old) and has high associated costs (~ $1 trillion per year). 60%-80% cases correspond to Alzheimer’s Disease (AD), which is expected to continue increasing exponentially in the next decades. At present, there are several disease-modifying treatments for AD in development, but once approved they will demand an efficient early detection of the disease to be effective. PET is the gold standard for prompt detection of AD's biomarkers (e.g. beta-amyloid and tau proteins), but traditional scanners are very big and expensive and they do not allow wide-population screenings. Positrigo is a Swiss start-up, aiming to develop NeuroLF brain PET system, which is only a tenth of the price (reduced device, personnel and radiotracers costs) and a fifth of the size of traditional scanners. It will allow to meet the expected large increase in PET examinations in the incoming years (when new treatments are approved) and make brain scanning affordable for everyone.  NeuroLF was developed with support from ETH Zurich, University of Zurich and University of Heidelberg, and thanks to decades of accumulated experience in particle physics from the team. The company also counts with world-class advisors for business and medical aspects.  Our potential market, based on the need for Alzheimer’s diagnosis for population older than 50 years, gives us around 20 M scans per year only in USA and the EU. Moreover, 1 NeuroLF scanner working at full capacity represents savings of about $ 200.000 per year for healthcare. We have developed the first prototype and preliminary tested standard performance parameters, as well as initially established in-house manufacturing, defined a regulatory roadmap, contacted some key stakeholders and identi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'An intersectoral innovative solution involving DIGItal tools, empowering families and integrating community CARE services for the prevention and management of type 2 diabetes and hypertension' (DigiCare4You).

assistant: **Concept**

DigiCare4You Consortium will jointly work with local stakeholders to deliver an intersectoral innovation involving digital tools for early screening, prevention and management of type 2 diabetes (T2D) and hypertension (HTN). An implementation study will be conducted, targeting more than 10,000 families in two Middle Income Countries (Albania and Bulgaria) and two High Income Countries (Greece and Spain), considering vulnerable groups. Schools will be used as an entry point to the community and building on an existing procedure for children’s periodic growth assessment (conducted via school nurses or in collaboration with local community health centres), parents/ caregivers will be screened via a non-invasive self-reported digital screening tool. Those identified at high risk for T2D will be referred for glycaemia testing and blood pressure (BP) measurements at local community health centres. Parents/ caregivers confirmed to have pre-diabetes or diabetes (and possibly high BP) will be invited to join a mHealth self-management intervention coordinated by the community healthcare workforce. The goal of this intervention is not only to improve the health status of the users, but also empower the entire family in adopting a healthy lifestyle. To this end, schools and communities will also be actively engaged to promote health literacy, well-being and support lifestyle changes creating a more supportive social and physical environment for the entire community. Regular monitoring will be ongoing during the implementation to allow corrective actions and ensure effective adaptation and uptake. Based on the study outcomes, the in-depth health economic evaluation and budget impact analysis, and data deriving from a Scalability Assessment and Decision-Support tool, national and int
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Viruses, Immune stimulation and RNA Interference in Oncology Network' under Horizon 2020.

assistant: **Concept**

The Viruses, Immune stimulation and RNA Interference in Oncology Network (VIRION) is focused on the execution of an internationally competitive cancer research project focused on the development of a novel therapeutic regime by combining immune therapy with oncolytic virotherapy and RNA interference techniques. Recent clinical successes have shown the immune system to be a powerful ally in the fight against cancer. While surgery, chemotherapy and radiation therapy remain the first lines of treatment for most tumors, immunotherapy regimens have had astonishing clinical successes. Furthermore, recent studies have shown that pre-existing lymphocytic infiltration of tumors is associated with superior prognostic outcomes in a variety of cancers and might improve cancer therapies targeting immune checkpoints. A recent development in the immunotherapy field is adoptive cell therapy (ACT). In ACT  lymphocytes from cancer patients are expanded ex vivo into more favorable numbers, they can be modified genetically or stimulated to relieve immune suppression and infused back into the patient. In clinical trials, ACT has resulted in anti tumor responses. However, immune suppression in the tumor microenvironment limits the efficacy of immunotherapy and remains a major hurdle. We aim to potentiate the antitumor immune reaction in the tumor microenvironment through the combination of immune therapy and oncolytic virotherapy. Oncolytic viruses are developed to specifically target and destroy tumor cells. In pre-clinical models, oncolytic adenoviruses have proven a powerful tool in the elimination of tumors, not only by their direct lytic effects but also by their triggering of a subsequent tumor inflammation and enhanced lymphocytic infiltration. VIRION will address how these immune res
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Advanced Fraud Detection System - Protecting digital transactions against cyber attacks' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

ThreatMark vision is to secure the assets of people/companies by better protection of digital transaction systems against cyber-attacks. It dramatically improves the detection & protection capabilities of cyber-operators against threats, fraud & incidents. It allows them to increase their security by complex preparedness, rapid detection and faster response.Advanced machine learning and unique algorithms of ThreatMark make the detection of advanced threats and behavioral anomalies more sensitive and reliable while lowering the cost of operation. We challenge the conventional methods of transaction protection by bringing usually fragmented features under one roof: (online) fraud detection systems, web fraud detection, web application firewall, malware detection, criminal and account takeover detection. This is unique and appreciated by users, as proven by recent competitor analysis. The solution has been designed to answer the business opportunity that lays in plausible cyber-security market trends:(1) Steady growth of online transactions & cyber attacks/ online fraud at the same time;(2) Rise of as-a-service model providers & market (9.8%/ p.a.);(3) Pressure to decrease high expenses for complex security.The ultimate goal of this project is to bring to market system ThreatMark capable of improving the security of transactions and decreasing the resources needed. Four target groups were identified: on-line banks, high value transactions providers, secure apps, emerging digital services. Some strategic alliances with business partners exist.The sub-objectives of FS include requirements analysis, detailed business plan, technology roadmap update and company development strategy based on innovation management training.The company has already invested into its technology mor
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Health system stewardship and regulation in Vietnam, India and China' to be submitted under Seventh Framework.

assistant: **Abstract**

The proposed project aims to investigate stewardship and regulation as it relates to governance of health systems in policy and practice. It aims to do so by developing an integrated approach to improved stewardship and regulation in health services in Vietnam, India and China, in order to support policy decisions in the application and extension of principles of accessibility, affordability, equity and quality coverage of health care in the three countries.  The health systems of Vietnam, India and China include a mix of types of health care providers including public and private sectors.  The private sector has grown rapidly in recent years with implications for equity and access.  Previous research in the three countries suggests that the stewardship and regulation capacity of the three governments is pivotal in improving policies regarding accessibility, affordability and quality coverage of health services. The project will use maternal health as a case study of stewardship and regulation of health care services. Maternal health is one of the key areas for policy and health care delivery in low and middle-income countries and is included in the Millennium Development Goals. The choice of Vietnam, India (one state) and China (one province) as study sites has been based on their high rates of overall maternal ill-health, and the spectrum of contextual issues that determine the need for adequate stewardship and regulation. The project will evaluate stewardship and regulation within and across the study countries, will identify gaps and will suggest ways of improving stewardship and regulation. The outputs will include policy guides for national and international health policy makers and recommendations for national standards of stewardship and regulation. The project