RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Virgil's «Georgics» in Italian Literature' under Horizon Europe.

assistant: **Concept**

The VirGIL (Virgil’s “Georgics” in Italian Literature) project aims to investigate the legacy of Virgil’s “Georgics” in Italy between the 15th and the 19th centuries, and its impact on agricultural and livestock breeding practices of that period, through an analysis of translations of Virgil’s poem and agronomical treatises. Indeed, until the Modern Age, the “Georgics” continued to be interpreted not only as a poem but also as a work capable of conveying precise notions for farmers and breeders. Although the first translations appeared at the end of the 15th century, it is primarily from the 18th century that they multiplied, revealing a renewed interest in the scientific themes of the poem. There are still no specific systematic studies on this topic: further research is therefore needed that integrates a philological approach with a translational and linguistic perspective. This project firstly proposes a transcription and in-depth analysis of verse translations of the “Georgics” in the period under consideration, to define the authors’ culture and understand how they translated Latin hexameters into Italian metric forms. Secondly, it involves an analysis of Italian poems directly inspired by the “Georgics” to highlight similar passages and determine the extent of their influence. Finally, by focusing on some key terms such as names of plants, agricultural tools and techniques, the project aims to identify points of contact between the corpus of translations and major agronomical treatises, to determine whether there are mutual influences or not. The expected result–understanding the relationship between the agronomical and naturalistic culture conveyed by Virgil’s “Georgics” and its reception in Italian culture, as well as how various metric forms deal with hexameter
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Deciphering PI3K biology in health and disease', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

The Phosphoinositide 3-kinase (PI3K) pathway is at the core of multiple fundamental biological processes controlling metabolism, protein synthesis, cell growth, survival, and migration. This inevitably leads to the involvement of the PI3K signalling pathway in a number of different diseases, ranging from inflammation and diabetes to cancer, with PI3K pathway alterations present in almost 80% of human cancers. Therefore, PI3Ks have emerged as important targets for drug discovery and, during 2014, the first PI3K inhibitor was approved by FDA in the US for the treatment of a lymphocytic leukaemia. Nonetheless, our understanding of PI3K-mediated signalling is still poor and only a fraction of the potential therapeutic applications have been addressed so far, leaving a large amount of translational work unexplored. Europe features a set of top quality research institutions and pharmaceutical companies focused on PI3K studies but their activities have been so far scattered. This proposal fills this gap by providing a multidisciplinary network (biochemistry, mouse studies, disease models, drug development, software development) and an unprecedented training opportunity from the bench to the bedside (from pre-clinical discoveries to clinical trials), through cutting edge molecular biology, drug discovery and clinical trial organization. The proposal is aimed at training young investigators in deep understanding of the different PI3K isoforms in distinct tissues and to translate this knowledge into a new generation of PI3K inhibitors, treatment modalities and into identify new uses for existing PI3K inhibitors.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'TITANIUM DIOXIDE – THE SILENT KILLER: FINDING THE RELEVANT BIOLOGICAL TARGET FOR EXPOSURE CHARACTERIZATION AND RISK ASSESSMENT OF NANOPARTICLES TOXICITY IN FISH MODEL', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

The nano-ecotoxicological research is supported and promoted by European Commission. In 2005, the Action Plan “Nanosciences and nanotechnologies: An Action Plan for Europe 2005–2009” was adopted (European Commission, 2004). The European Commission clearly states the need for the new scientific experiments that will provide quantitative data on toxicology and ecotoxicology and allow for the risk assessments to be carried out on nanomaterials. In year 2006 the Chemicals Committee of the OECD has formed special Working Party on Manufactured Nanomaterials [WPMN]. One of the nanomaterials included in the OECD WPMN priority list is titanium dioxide (TiO2). Titanium dioxide nanoparticles (nano-TiO2) present the biggest ecotoxicological concern due to the rapid increase of anthropogenic input into the environment. Estimated environmental concentrations of nano-TiO2 in water range from 0.7 to 24.5 ng/mL.CURRENT AQUATIC EXOTOXICOLOGY TESTING OF NANO-TIO2 ARE NOT SUFFICIENT FOR THE RISK ASSESSMENT, as the testing is done by exposing the aquatic organisms to water suspension of nano-TiO2. Although the nano-TiO2 can be absorbed by the gills and skin of aquatic animals, the absorbed amount is insignificant compared to the potential of uptake through diet. Based on our previous research (Jovanovic et al., 2011, Jovanovic & Palic , 2012) we have classified nano-TiO2 as a potent immunotoxin, and there have been no previous studies that have investigated synergistic effects of nano-TiO2 during co-exposure to pathogenic bacteria. Therefore, we propose to use multidisciplinary approach by combining immunology assays, bacterial challenge studies, gross pathology of the brain, kidney and liver, and next generation deep gene sequencing - in order to determine toxicological effects and relevan
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Advanced manufacturing technology for automotive chassis components through extensible and sustainable use of mg alloys' under Fifth Framework.

assistant: **Concept**

Fuel consumption and CO2-emission of passenger vehicles are associated with a growing demand for low weight components. As a consequence magnesium has recently gained importance due to its low density and the high strength to weight ratio. However, the existing Mg-alloys are not suitable for thick components requiring high strength and ductility. Furthermore, the current manufacturing technology has to be modified in order to fulfil the requirements of a high volume production. Therefore, the overall objective proposal is to develop a suitable manufacturing technology for the production of lightweight Mg-Chassis components and to validate this for two demonstrators. New Mg-alloys with improved mechanical properties and better corrosion resistance shall be used for the manufacturing of the demonstrators. Improved joining techniques are necessary targets for an appropriate assembling of Mg-components. A fatigue life estimation method and quality assurance methods for highly loaded parts will contribute to the design guidelines for Mg components.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Development and application of high performance ultrasonic resonator systems for splitting of emulsions' to be submitted under Fourth Framework.

assistant: **Abstract**

The proposed project is focused on the ultrasonic splitting of emulsions into the two liquid phases. This is an especially promising approach, since the liquid particles, ones coagulated, remain stable as a homogenous phase which can be separated easily and permanently by gravitational forces. The main objectives of the proposed research project are: (a) The further development and understanding of the acoustic coagulation and separation effect as well as the stimulation of innovative alternatives in the process and waster water treatment including recycling of the separated phases. (b) The development and application of novel high performance ultrasonic resonator chambers for splitting of oil-in-water emulsions The training content comprises: (1) The numerical investigation of the influence of all system parameters on the magnitude of the forces. (2) The theoretical analysis and design of different concepts of appropriate piezoelectric composite resonator chambers.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Proliferation and Migration under External Constraints', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Cell proliferation lies at the heart of the threat posed by tumours. It involves cellular growth, division and migration. The tissue surrounding a tumor physically limits its proliferation, which implies that cells that are able to produce effective tumour growth, as well as cells that migrate out of the original tumour, have been able to circumvent this physical limitation. Other factors in tissues, however, can contribute to stop cell proliferation, making it difficult to precisely evaluate the contribution of physical confinement. In this project I propose to specifically address the effect of physical confinement on normal and cancer cells that are dividing and migrating, using new pathophysiologically relevant in vitro approaches. More specifically I propose two main objectives, related to the pathogenic potential of tumour cells:1) Discover specific mechanisms that allow dividing cells to push surrounding tissue (a process known as mitotic cell rounding) and demonstrate that alterations in this process can lead to spindle assembly defects and eventually to mitotic cell death. This will open a new set of targets to specifically kill dividing tumour cells.2) Discover specific mechanisms that allow migrating cells to squeeze their nucleus through narrow gaps. The nucleus has been shown to be the main physical barrier to cell migration in tissues, and two types of cells are able to migrate through narrow gaps: immune cells and metastatic cells. By comparing these two types of cells, we hope to uncover mechanisms specific to metastatic cells, thus providing targets for anti-metastatic treatments that would not harm immune cells function.Understanding how cancer cells can achieve efficient proliferation and migration under external constraints will aid the design of new
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Comparison of conservation materials and strategies for sustainable exploitation of immovable industrial cultural heritage made of iron and steel' will create measurable scientific, societal and economic impact aligned with Sixth Framework.

assistant: **Impact**

Closed down, but outstanding examples of industrial monuments have to be considered as important witnesses of our cul-ture. New preservation strategies are requested for large outdoor monuments, being heavily corroded and mechanically endangered. The pro ject will concentrate on the comparative testing of established traditional, modern, and within the pro-ject developed new surface conservation materials and preservation strategies for industrial heritage made of iron and steel. The laboratory tests wil l require the application of suitable transparent compounds like traditional oils and waxes, comparing them with micro-crystalline waxes, modern resins like acrylics or epoxy-functionalised lacquers, and newly de-veloped coatings such as the combination of isocyanato-based polyacylate dispersions (as silanes) and hybrid polymeric sols, leading to advanced hybrid systems by nano-scaled sol-gel preparation techniques. Room-temperature curing will be obligatory for its applications. The influence of differe nt degrees of surface cleaning on the protective effect of the coatings will be specified. The conservation material development will respect standards set by conservation ethics, focussing on the reversibility and re-treatability of transparent coatings . The newly developed systems will be water-based and thus provide an alternative to solvent-based lacquers and natural resins available so far. Pilot applications of the most promising coatings on three selected objects in Ireland, Poland, and Germany wi ll be performed to compare the advanta-ges of the new materials with the commercially available systems. Management concepts for industrial heritage sites will be established to demonstrate the potential for economic growth through the application of new methodologies.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Artificial Intelligence beyond quality' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

In the automotive industry, quality is the key differentiating factor. Scraps and defects represent a major risk to performanceand competitiveness, leading to very high costs. Besides, there is no specific solution in the market for the automatic qualitycontrol of defects in plastic injection and painting defects, forcing manufacturers to maintain primitive techniques based onhuman vision, that can be time-consuming and costly.By applying Artificial Intelligence (AI) to visual inspections, organisations can identify defects by matching patterns to imagesthat were previously analysed and classified. They could be detected up to 90% more accurately than humans. In addition,reduction of personnel costs, rework, and scrap yields a total cost reduction of approximately 9% (~ €26 billion). A newmarket report from Market&Market claims that automotive AI will reach €9.37 billion by 2025, at a CAGR of 38.46%.TECHEYE® is an innovative solution offering a fully automated directional vision system coupled with a self-calibrationlighting unit, based on Neural Networks. It comprises suitable hardware for images acquisition, a communications systemand software for image processing and analysis.Our algorithms can automate visual inspection activities, even under complex conditions like variable position, orientation ofunits or tough lighting conditions. TECHEYE® is able to classify injection faults: gusts, ampoules, pores and scratches.We offer an affordable web service, user-friendly as plug and play, enabling defect classification. TECHEYE® can be reallysuitable for automotive OEMs and plastic injection companies to enhance their production lines, the quality assurance andcost reduction.INOVALABS is a technical consulting company founded in 2004 in Vigo (Spain), providing services re
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Pathways for Phosphorus (and Nitrogen) Release from Sediments of the Tamar Estuary (SW England) and the Gippsland Lakes (Australia) Eutrophic Ecosystems: Diagenesis Experiments and Modeling' goes beyond current state-of-the-art under Sixth Framework.

assistant: **Innovation**

European coastal ecosystems because the nutrient load has greatly increased in recent years through human activity. Phosphorus has a critical role in the eutrophication of water bodies, the adverse effects of which are most apparent during algal blooms. Algal outbreaks of cyanobacteria (blue-green algae) carry significant risks to human and animal health, as well as a major economic cost. Ecosystems are particularly badly affected, to the extent that toxic algal blooms occur annually, accompanied by fish kills and significant loss of recreational and conservation value. High priority is given to minimization of phosphorus inputs to rivers and waterways. Despite these measures, algal blooms may continue to occur on a seasonal basis years after phosphorus inputs have ceased, and it is thought that this is due to periodic remobilization of phosphorus bound in the sediments. This remobilization may occur as a result of changes in redox condition, pH, ionic strength or bioturbation, but as yet, the factors controlling this complex biogeochemical process are only poorly understood. Because to date most coastal water eutrophication research has focussed on the water column, the objective of the proposed research is to increase our understanding of the role of coastal sediments in the seasonal storage and recycling of Phosphorus (and Nitrogen). This project will provide new data, which are essential for enhanced environmental monitoring and decision support systems, and will contribute to realistic diagenesis modeling. It will aid our capacity to predict environmental change and allow us to develop better strategies for prevention, mitigation and adaptation in the management of coastal and estuarine ecosystems in the European Union.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Continuous electrolytic-catalytic decoupled water electrolysis for green hydrogen production' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

H2Bro will develop a transformative decoupled water electrolysis process for green hydrogen production. It aims for high efficiency in a continuous and isothermal process that supports membraneless electrolysis with high-throughput and minimal energy losses, going far beyond other electrolysis processes. I propose to achieve these goals by dividing the oxygen evolution reaction into two sub-reactions, electrochemical and chemical ones, carried out in different cells. Towards this end, I propose to use a soluble redox couple that will be oxidized electrochemically while hydrogen evolves at the cathode in one cell, and reduced spontaneously in the presence of a catalyst in a chemical reaction that evolves oxygen in another cell. I have identified the bromide/bromate couple as a promising candidate due to its high solubility and suitable redox potential. Fundamental materials challenges will be addressed in developing the electrolytic process with an aim to achieve high efficiency and selectivity to produce bromate without volatile side products such as O2 or other loss reactions, and a suitable catalyst for spontaneous bromate reduction and oxygen evolution. Addressing these challenges requires a multidisciplinary research in materials science, electrochemistry, catalysis and process engineering, where questions of materials selection and catalyst activity and selectivity intertwine with process parameters such as electrolyte composition, temperature and flow, with an ultimate goal of combining the electrolytic and catalytic sub-processes into a seamless process in a flow system that generates hydrogen and oxygen in different cells at high efficiency and rate. Progress towards these aims will lead the way to a competitive solution for green hydrogen production to fight gl
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fifth Framework proposal on 'Specifying Legal Terms of Contract in ICT Environment'.

assistant: **Concept**

A barrier for the practical use of modern ICT (Information and Communication Technologies) is the lack of regulations for this environment. The result is that ICT is used for information and documentation exchange in parallel to the use of paper leading to extra costs. The tools developed in this project will define a framework for legal conditions and contracts regarding the use of ICT in project business, which will make it possible to get rid of the paper-based mentality -legally admissible. Participants in a virtual enterprise will be able to communicate purely electronically, without using paper any more.Objectives are to:(1) define industrial requirements(2) define the legal basis for contracts on ICT use in the virtual enterprise,(3) develop tools for contract negotiation and authoring,(4) test and validate results and(5) promote deployment by IT vendors, legal experts, industry, academia and standardisation.Objectives:ICT based information exchange in project based business such as construction and large scale engineering has become common but is not properly covered by the contractual practice. The full use of inter-enterprise ICT is hampered by poorly defined responsibilities, overlapping communication techniques and mistrust. The goal of this project is to define a framework for legal conditions and contracts regarding the use of ICT in project business. The objective is to specify user requirements, implement legal support tools & promote an enhanced business practice in which the use of ICT in inter-enterprise information exchange is contractually stipulated. The measurable and tangible objectives of e-LEGAL are: define industrial requirements, define the legal basis for contracts on ICT use in virtual enterprise, develop tools for contract negotiation and