RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Traitor-virus-guided discovery of antiviral factors'.

assistant: **Objectives**

Viruses may seem smart since they rapidly develop new skills to spread in humans. However, they are actually just masters of trial and error. Their short generation time, enormous reproduction and high variability allows viruses to try countless variations. A few of these will enhance viral spread and, in the worst case, enable viral pandemics. It is conceivable that viruses evolve to counteract those defence mechanisms that would otherwise be most effective against them. Usually, it is hard to assess why specific changes are advantageous. This is especially true for adaptations enabling viral pathogens to counteract innate antiviral factors because these cellular proteins and their viral antagonists are numerous and highly versatile. Here, I propose to combine the advantages of the revolutionary CRISPR/Cas9 technology with the enormous adaptive power of viruses to develop a novel approach allowing robust, specific and genome-wide unmasking of antiviral mechanisms. In principle, we will equip HIV-1 with genetic scissors to convert them into traitor viruses revealing their cellular opponents. To achieve this, we will generate libraries of replication-competent HIV-1 constructs expressing guide RNAs as genetic tools with the potential to inactivate every human gene in Cas9 expressing cells. Virus variants expressing guide RNAs eliminating antiviral genes will be selected by in vitro passaging and identified by next generation sequencing. Utilization of different viral backbones will allow the discovery of key defence factors against viral zoonoses and spread in humans. Finally, we will determine the antiviral spectrum and inducibility of innate antiviral factors to identify vulnerabilities of viral pathogens that can be exploited in preventive and therapeutic approaches.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Electrical and optical characterization of artificial atoms using space-charge spectroscopy' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

Research objectives and content The research in semiconductor physics is at present to a large extent focused on quantum dots (QDs). QDs are nanometer-sized Q structures with electronic confinement in all three dimernsions. QDs are very interesting both from the point of view of fundamental physics, and for technological applications due to the unique possibility to tailor the electronic structure and, accordingly, the electrical and optical properties. In the proposed project we intend to investigate the electrical and optical properties of QDs realized in technologically important material systems e.g. Si/SiGe and InAs/GaAs by space-charge spectroscopy. From these studies we expect to obtain detailed information on the electronic structure, band-offsets, electron- electron-interactions and electron-phonon coupling. Also the role of doping on the properties of the QDs will be investigated. Training content (objective, benefit and expected impact) The field of spectroscopy on QDs is new to me. In order to get the necessary experience to build up a research area in Lund on this fascinating topic it is of greatest importance to me to have the opportunity to spend a longer time at a research laboratory in the frontier. Since, the semiconductor group headed by Prof. Kotthaus at LMU of Munich is world-leading in the field of space- charge spectroscopy on QDs, I can not think of any better host institution to acquire the proposed training. Links with industry / industrial relevance (22) The proposed project is linked with an industrial project concerning SET devices (Siemens, Dr Rischat)
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Statistical learning and L2 literacy acquisition: Towards a neurobiological theory of assimilating novel writing systems' under Horizon 2020.

assistant: **Concept**

The overarching goal of L2STAT is to understand L2 literacy acquisition by bringing together, for the first time, recent advances in the neurobiology of statistical learning (SL), a detailed statistical characterization of the world’s writing systems, and neurally-plausible general principles of learning, representation, and processing. L2STAT aims to provide a new theoretical framework that considers L2 learning and SL a two-way street: SL, on the one hand, tunes learners to the regularities of a new linguistic environment, and on the other hand, L2 environment shapes learners’ sensitivity to its specific types of statistical properties. The project will focus on the assimilation of reading skills in four novel linguistic environments, and investigate how exposure to their distinct writing systems shape, in turn, SL. L2STAT is an interdisciplinary project that launches in parallel five mutually informative research axes: 1) we employ advanced methods from computational linguistics and machine learning to precisely characterize the statistics of four highly contrasting writing systems (English, Spanish, Hebrew, Chinese). 2) We study the learning that results from biologically-inspired computational models that are exposed to these statistics, to generate a priori predictions regarding what statistical properties can (or cannot) be learned, and how neural mechanisms constrain the representations learned during L2 literacy acquisition. 3) We develop psychometrically reliable behavioral tests of individuals’ capacities to extract regularities in the visual and auditory modalities. 4) We use state of the art neuroimaging techniques including EEG, MEG, fMRI to probe the neurobiological underpinning for detecting regularities in the visual and auditory modalities. 5) We condu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Coordination for Efficient and Green Urban Mobility' under Horizon 2020.

assistant: **Concept**

Traffic hotspots in Europe are expected to generate over 203 billion Euro of economic cost by 2025. Traffic congestion in cities raises serious concerns on the level of CO2 emissions, fuel consumption and discomfort to drivers due to prolonged travel time and large idle time behind the red lights. Unnecessary acceleration and deceleration towards traffic junctions can also highly contribute to extensive use of fuel, increase in emissions and engine and brake wear. Current traffic signal control approaches are not adequate for tackling the problem because they focus on traffic flow efficiency and disregard the individual drivers’ interests. The aim of this project is to develop a method that does not only coordinate all the traffic signals in an urban network, but also takes the vehicle speeds in to account and effectuates a coordination between the traffic lights and vehicle speeds alike. Such a coordination will make the most of the infrastructure and technological developments for reaching an efficient, eco-friendly, and safe urban mobility. Due to the complexity and stochastic nature of the traffic system, the coordination problem will be addressed by integrating model-based distributed control techniques with reinforcement learning-based algorithms. Comprehensive analysis and benchmarking will be performed to obtain a complete evaluation of the idea and prove its effectiveness in improving urban mobility with respect to different indices like fuel consumption, CO2 emissions and number of stops. Adaptive cruise control systems already installed in a large number of cars in European countries. Automakers are announcing the marketing of autonomous cars in the coming years. Soon European cities should be ready to make the most of these technological developments to prov
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Not all minds that wander are lost: A neurocognitive test of mind-wandering state’s contribution to human cognition.' (WANDERINGMINDS) under Horizon 2020.

assistant: **Objectives**

Experience does not always arise from the events in the immediate environment; research has shown that states such as mind-wandering occupy almost half of our waking thought. Although mind-wandering has gained a foothold in cognitive science, our understanding of this core form of cognition is piecemeal and disjointed, making it a regular topic of theoretical debates in high-profile journals (e.g. Science and Psychological Bulletin). I have argued that these controversies are due to the lack of a coherent framework in which to explore mind-wandering’s role in cognition. In particular, a key problem is overcoming simple views that propose that mind wandering is merely a state that leads to errors, or unhappiness; accounts that persist in the face of evidence that it contributes foresight and originality to human thought.This project will allow me to assemble a team of researchers and develop an account of how mind-wandering contributes to creative and novel thinking and how it can be regulated to prevent interference with ongoing action. We will explore the experiential categories of the state using novel experience-sampling methods I have developed and explore its neural basis using functional Magnetic Resonance Imaging (fMRI). Using these measures, we will: (i) identify the neural correlates of different categories of mind-wandering experiences, (ii) use these metrics to explore the mechanisms that underlie the creative properties of thinking during mind-wandering, (iii) identify how this creative mode of thought is managed so as not to disrupt important goals in the here and now (such as learning) and (iv) explore these processes in the context of both controlled laboratory studies and longitudinally in the real world by assessing their beneficial role in academic per
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Basal ganglia mechanisms in motivation and learning' demonstrating excellence, impact and implementation quality for a Fourth Framework call.

assistant: **Abstract**

We plan to study how the motivational control of behaviour is achieved by neuronal mechanisms operating in the basal ganglia.  This issue will be investigated by behavioural experiments, by neurophysiological recordings in behaving animals during specific learning situations, by imaging studies of humans performing learning tasks, and by neuropsychological investigations of human patients suffering from basal ganglia diseases. Convergent lines of evidence suggest that the basal ganglia are importantly involved in the control of voluntary, goal-directed behaviour. However, it is largely unknown how neuronal mechanisms in these structures provide a physiological basis for the deficits occurring in human diseases and in experimentally lesioned animals. In particular, we would like to know how the motivational control of behaviour is achieved by neuronal mechanisms operating in the basal ganglia. This issue will be addressed at different levels of experimentation by asking the following questions: (i) How do motivational variables control learning in animals? The experiments will test the learning behaviour of rats under different degrees of motivation. (ii) With these behavioural variables in mind, how do individual basal ganglia structures participate in learning, and in which forms of learning? The experiments will be done with lesions of specific nuclei of the basal ganglia of rats and monkeys which learn and perform specific tasks involving basal ganglia mechanisms of reward processing and procedural motor and habit learning. (iii) Can we find single neurone correlates in the basal ganglia for specific motivational processes defined above, notably the processing of reward information and mechanisms underlying particular forms of learning? The experiments will involve t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'European Sensor System for CBRN Applications' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

The EU-SENSE project will provide an innovative technical solution to deal with selected shortcomings in CBRNe protection indicated in the ENCIRCLE Catalogue of Technologies. The created system will be a step-forward in chemical detection by developing a novel network of sensors that exploits advanced machine-learning and modelling algorithms for improved performance. The salient objectives of the project include development of an adaptable and multipurpose threat detection system (network of sensors, comprising both stationary and person-worn sensor nodes supported by environmental noise learning algorithm for false alarm rate reduction) and tools for enhancing situational awareness based on the sensor data (threat source location estimation and hazard prediction solutions). In general, the developed system will improve the threat detection capabilities and will increase state-of-the-art sensors reliability by networking and novel algorithms.Moreover, the project will implement a dedicated mode covering CBRNe practitioners training aspect. The mode will be an integral part of the system and will allow for familiarization with the equipment (the system) as well as training and rehearsal for specific situations.The EU-SENSE will be strongly user-driven and the demonstration of the developed system will be conducted in the realistic working conditions, in the professional firefighters training centre and with the use of chemical simulants. The project will also consider the issue of interoperability between various chemical sensors and will propose a concept for standardisation of sensor network description.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Furthering Less Congestion by creating Opportunities for more Walking and cycling' to be submitted under Horizon 2020.

assistant: **Abstract**

FLOW sees a need for a paradigm shift wherein non-motorised transport (often seen from a transport policy perspective simply as a nice “extra”) is placed on an equal footing with motorised modes with regard to urban congestion. To do this, FLOW will create a link between (currently poorly-connected) walking and cycling and congestion by developing a user-friendly methodology for evaluating the ability of walking and cycling measures to reduce congestion. FLOW will develop assessment tools to allow cities to evaluate effects of walking and cycling measures on congestion. Our aim is for the tools to become the standard for assessing the impact of walking and cycling measures on congestion. The tools include a congestion impact assessment (including socio-economic impact, an assessment of soft measures, congestion evaluation based on KPIs and a cost benefit analysis) and traffic modelling. Current modelling software will be calibrated and customised in FLOW partner cities to analyse the relationship of cyclist and pedestrian movements to congestion.The modelling and impact assessment will identify the congestion reducing effect of walking and cycling measures. FLOW partner cities will develop implementation scenarios and action plans for adding or up-scaling measures that are shown to reduce congestion. FLOW will target three distinct audiences, with appropriate materials and messaging for each. Cities will learn about the value and use of new transport modelling tools, businesses will be made aware of the potential market in congestion busting products and services and decision makers will be provided with facts to argue for walking and cycling to be put on equal footing with other modes of transport. FLOW will meet the challenge of “significantly reducing urban road cong
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Electronic Chemical Cell' (ECCell).

assistant: **Concept**

ECCell<br/>The aim of the project is to establish a novel basis for future embedded information technology by constructing the first electronically programmable chemical cell. Thisis naturally a high-risk, embryonic research project, but aimed at a breakthrough which will lay the foundation for immersed micro- and nanoscale molecular information processing with a paradigm shift to digitally programmable chemical systems. Chemical cells must combine self-replication, self-containment and self-regulation of resources (metabolism) enabling evolution to qualify as alive. ECCell will employ novel families of fully synthetic hybrid informational polyelectrolyte copolymers (not simply DNA), which simultaneously support all three cell functionalities. Their microscopic multiphase self-assembly under electric field control is the primary information processing mode of this technology. Realtime digital electric field control sequences, regulating the semi-autonomous self-assembly and reactive molecular processing, will both provide an online programming methodology for these complex systems and potentially serve as electronic genomes for the chemical cells. Programming methodologies (beyond optimal control theory) will be explored and evaluated which deal effectively with the remote real time distributed regulation of these novel semi-autonomous combinatorially complex chemical systems. The research will establish an effective IT interface between microelectronic and molecular information processing, by demonstrating its use to achieve a hard chemical synthetic systems objective (an artificial cell) opening a platform for programming a novel chemical living technology at the microscale.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Preparing the FLACS code for commercialisation' (FLACSCOM).

assistant: **Concept**

Gas explosion is a major safety risk on petro-chemical production and processing facilities. The cost of gas explosion accidents is very high in terms of loss of lives, of facilities and lost production. The Piper Alpha accident in 1987 costed 167 lives and loss of facilities alone was over 2 billion pounds sterling. The petrochemical industry requires reliable methods to quantify and hence effectively manage their gas explosion risk, e.g. minimising the consequences of a gas explosion by design.FLACS is a research tool which describes the processes involved in gas explosions, namely, the interaction of combustion generated turbulence and combustion. It is the result of 16 years of intense fundamental research (and is still ongoing) into gas explosion propagation in offshore environments. It is supported mainly by oil and gas companies. Total expenditure to date exceeds 15 million ECU. The main part of this research was to generate experimental data and theoretical knowledge needed to produce FLACS. It has been applied to quantified gas explosion risk (quantified risk assessment studies) and in design (minimising the risk of escalation, such as. fire, and in structural failures).The aim of the proposed FLASCOM project is to make available to the industry the product of state-of-the art gas explosion technology, and to speed up the process to commercialise FLACS by rigorously testing (beta testing) by target users, and detailed review by IT engineers.In the project, FLACS will be used by petrochemical, oil and/or gas companies and an engineering consultant. They will use the code during a 14 month period applying it to a variety of gas dispersion and explosion problems offshore and in land-based installations. The installations will vary from open geometries to very conf