RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Habitability of Exo-Earths in various atmospheric oxidative conditions' under Horizon Europe.

assistant: **Concept**

Among the thousands of extrasolar planets discovered, Earth-like objects focus our attention to seek new habitable worlds. Eleven Earth-sized planets have already been discovered in the Habitable Zone (HZ) of their host-star, including three in the TRAPPIST-1 planetary system. Deciphering their atmospheres is the challenge of the next decade in exoplanetary science, stressing out urgent needs in fundamental data for these objects.My aim is to investigate how the atmospheric organic reservoir forms and evolves in the frame of humid exoplanetary atmospheres in Habitable Zone. I will also quantify the impact of theses processes on the climate and on the potential for prebiotic chemistry on these planets. I propose to consider the role of organic aerosols as prebio-signature: those are nanoparticles chemically produced in the atmosphere. I will address the capacity of exo-Earths atmospheres to produce organic aerosols in various oxidative conditions, and their further physical and chemical interactions with atmospheric water. To tackle these questions, I will combine experiments and models to discover the reactivity that occurs in atmospheres within an extensive range of oxidation conditions. I will experimentally determine the physical properties of the aerosols, and then model their radiative impact and their propensity to generate clouds in the atmosphere. I will also experimentally identify the prebiotic molecules composing the aerosols that dissolve into clouds. This transfer from the dry organic reservoir towards liquid water is indeed critical for the emergence of life.The ERC-AdG Oxyplanets project will contribute to interpret and suggest observations for the future NASA-JWST and ESA-ARIEL space missions. Furthermore, it will reinforce our knowledge of the habitabil
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Application of new bond and coat technology to advanced hybrid semiconductor power package devices to increase integrity, reduce costs and simplify design' under Fourth Framework.

assistant: **Concept**

The identified route to realising the objective was to manufacture semiconductor packages from the Transient Liquid Phase (TLP) bonding of high volume silicon carbide particulate loaded aluminium alloy Metal Matrix Composite (MMC). The deposition of the alumina substrate and copper tracks, prior to integration of the semiconductor components, was to be developed based upon the use of High Velocity Oxyfuel (HVOF) spraying. At the closure point of the project the preferred MMC material had been procured and had undergone preliminary evaluation. This included initial TLP bonding trials using silver and copper at the interface. HVOF spraying had been successfully demonstrated for the deposition of copper tracks in a defined pattern onto the insulating alumina substrate and the HVOF spray deposition of alumina onto MMC coupons. However, an assessment of the costs associated with the TLP bonding route for the fabrication of the semiconductor packages indicated that the process would not be economically viable. In addition, technical delays were encountered during the initial period in the development of the HVOF powders and the TLP bonding of the MMC to form demonstrator packages. At the mid-term point it was felt that, due to the above reasons, the objectives of the project could not be attained within the time and budget constraints of the CRAFT scheme. Hence the decision was taken to close the project at the mid-term.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'MULTILINGUAL INDEXING, NAVIGATION AND EDITING EXTENSIONS FOR THE WORLD WIDE WEB' (MULINEX), addressing dissemination and exploitation.

assistant: **Impact**

MULINEX addresses problems encountered by providers and seekers of multilingual information on. the WWW. For information providers, Mulinex will provide translation, content structuring, and multilingual indexation tools which are intended to lower the threshold at which the provision of multilingual content becomes economically feasible. For information seekers, the project will provide advanced multilingual facilities for access, navigation, browsing and filtering of multilingual information. End users of the application will require only standard WWW browsers. The system overall will be realised as a group of interacting tools which provide the necessary functionalities, including the retrieval of documents in different languages with a monolingual query and integrated machine-aided translation facilities. User needs will be analysed on the basis of current and planned multilingual web offers by the two major WWW service providers in the consortium.There has recently been a dramatic change towards commercial applications on the Web which has given rise to an enormous volume of information. This has become almost unmanageable for the information seeker despite existing web search engines. Tools such as Alta Vista, Lycos and Yahoo are used by many people as their primary navigation aid. Since the language of the Web is still predominantly English, these tools mostly cater for monolingual searches. However, the number of documents in other languages is increasing, together with the number of users who are non-native English speakers with varying levels of English language skills and knowledge. There are currently no adequate tools for managing multi-lingual document collections on the Web which allow documents to be presented in the language preferred by the user, and w
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Lipid droplet hypertrophy : the link between adipocyte dysfunction and cardiometabolic diseases' in the context of a Horizon 2020 call.

assistant: **Objectives**

The goal of SPHERES is to understand the dynamics and consequences of adipocyte hypertrophy (enlargement) through investigation of its large lipid droplet (LD). The adipocyte LD is a unique organelle specialized in storing energy in triglycerides (TGs). Its surface is composed of a phospholipid monolayer and specific LD-associated proteins (such as perilipins, CIDEs and lipases), which jointly regulate LD stability and TG turnover. Adipocyte hypertrophy due to an increase in LD size may, irrespective of body fat mass, cause a wide range of pathological conditions, notably cardiometabolic diseases. SPHERES PIs (Langin, Rydén, Antonny) postulate that disturbances in the interactions between LD proteins and LD lipid composition lead to adipocyte hypertrophy and its deleterious consequences. We have identified three fundamental unanswered questions: what determines the unique structure and dynamics of large LD; why does increased LD size alter the functional phenotype of the adipocyte; which factors cause inter-individual variations in LD size. To address these questions, SPHERES gathers expertise in clinical and cellular studies on human adipocytes, in/ex vivo investigations in mouse models, and biophysical analyses of LDs. At the core of this application is the development of beyond-state-of-the-art models and methods (spheroid cultures, native large LD preparation and reconstitution, proximity labelling of LD proteins, gene editing in cell and mouse models, and advanced LD imaging), only achievable through joint integrated effort of the PIs and co-workers. Spanning from molecular, cellular to the whole-body level, SPHERES will link new knowledge on the formation and maintenance of large adipocyte LDs to the deleterious impact of adipocyte hypertrophy. Altogether, SPHERES
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Proposal for a Horizon 2020 Design Study on the “European Plasma Research Accelerator  with eXcellence In Applications“ (EuPRAXIA)' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

EuPRAXIA will produce a conceptual design report for the worldwide first 5 GeV plasma-based accelerator with industrial beam quality and user areas. EuPRAXIA is the required intermediate step between proof-of-principle experiments and ground-breaking, ultra-compact accelerators for science, industry, medicine or the energy frontier (“plasma linear collider”). The study will design accelerator technology, laser systems and feedbacks for improving the quality of plasma-accelerated beams. Two user areas will be developed for a novel Free Electron Laser and High Energy Physics detector science. An implementation model will be proposed, including a comparative study of possible sites in Europe, a cost estimate and a model for distributed construction and installation at one central site. EuPRAXIA will be a new large research infrastructure with an estimated footprint of about 250 m. If the design study is approved, then it will lay the foundation for a possible decision on construction in 2020. A consortium of 16 laboratories and universities from 5 EU member states has formed for preparing this proposal. 18 associated partners from 8 countries have joined with in-kind commitments (linking 3 additional EU member states). The scientists represent expertise from accelerator operation for photon science and HEP, design and construction of leading accelerators like LHC and Soleil, advanced acceleration test facilities like SPARC and frontier laser projects like CLF, CILEX-APOLLON and ELI. A project with 14 work packages has been defined, 8 of them with funding requested from EU. The proposal has been discussed in the European Steering Group for Accelerator R&D (ESGARD). A statement of strong support has been received. The EuPRAXIA technology is closely linked to EU industry. The
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'An integrative multi-omics based approach to determining the rate-limiting factors of the production of anti-insect sesquiterpenes in Solanum habrochaites'.

assistant: **Objectives**

Between 20-40% of global crop production is lost to pests annually, with the majority of crops never reaching their genetic potential for yield. Certain plant species, like wild tomato (Solanum habrochaites), produce Type-VI glandular trichomes containing high levels of specialized metabolites such as sesquiterpenes, which confer a natural resistance against biotic stress. Although tomato cultivars develop type-VI glandular trichomes, their cultivated varieties have lost the capacity for terpene accumulation at protective levels. Attempts by the host lab at reintroducing sesquiterpene-biosynthesis genes into cultivated tomatoes did not result in sufficient terpene accumulation to confer pest resistance. The bottleneck lies not in terpene biosynthesis alone but in the accumulation capacity of these natural defense compounds, indicating additional, yet unidentified factors (e.g. precursor flux or transport) required for driving high terpene accumulation.The project aims to compare wild (high-terpene producer) and cultivated (low-terpene producer) tomatoes to identify the molecular mechanisms regulating terpene accumulation capacity. First, I will use integrative multi-omics, combining transcriptomics, proteomics, and metabolomics of type-VI glands, to uncover the key genes, proteins, and metabolites that modulate accumulation capacity between the high- and low-producer lines during trichome development, offering a holistic view of terpene biosynthesis. Secondly, I will validate rate-limiting candidate genes using Tobacco Rattle Virus (TRV)-based Virus-Induced Gene Silencing (VIGS) system in a hypermutable tomato variety.The proposed research could significantly facilitate the development of pest-resistant tomato varieties, reducing reliance on pesticides and improving cro
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Network for Cloud Computing Eco-System' (CLEANSKY) targeting Seventh Framework.

assistant: **Abstract**

With the increasing demand for cloud computing services and rapid development and advances in data center techniques, cloud computing is moving from small data centers towards a large scale, highly efficient new computing infrastructure with low cost. The proposed CleanSky network is intended to provide a stimulating and structured platform for the training of young researchers, for the development of innovative ideas and key concepts in the strategic emerging area of cloud computing: data center evolution, consolidation and service migration associated with the “eco-system” of cloud computing.The centric objective of CleanSky is to embed a pool of postgraduates and young researchers in a multidisciplinary, international and intersectoral environment of research activities aiming at developing  innovative methodologies and approaches (1) to satisfy application requirements and ensure efficiency within the emerging cloud computing paradigm, and (2) to optimize the energy and provisioning costs of individual data centers, (3) to consolidate, when necessary, multiple data centers through service migration and cloud resource pooling, and (4) to exploit renewable energy sources in cloud data centers.The development of this multidisciplinary training programme, reaching beyond any existing postgraduate programme in the field of cloud computing systems, brings together the academic competence and industrial know-how in multiple disciplines (computer systems, communications, scientific computing, performance engineering, optimization theory and technological economics) that are needed to address the technical and scientific foundation behind the evolution of cloud computing “eco-system”. By establishing structured training for young researchers, the CleanSky is intended to not
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fifth Framework proposal on 'Euromagpar'.

assistant: **Concept**

The main objective of this EuroConference is to bring together some of the keynote Community senior scientists and young researchers working in the topic of fine particle magnetism. Magnetic fine particles and related materials (nanostructured and nanocomposited systems) are constituted by magnetic entities of nanometric size, which present new magnetic phenomena (unusual property combination and both enhanced and diminished values of the magnetic properties, with respect to conventional bulk materials). This complex behaviour is related to the importance of size effects, surface properties, shape distribution and interactions among the variety of magnetic nanostructures embedded in the composite material.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Smart data-based assets and efficient rail freight operation' (2014-2020) targeting Horizon 2020.

assistant: **Abstract**

The objective of the FR8RAIL III project is to further develop technologies which are relevant for the rail freight sector to reach the goal highlighted in the S2R Strategic Master Plan. The work is partly based on results achieved in the previous projects of the AWP 2015/167 (FFL4E, ARCC, FR8RAIL), the AWP 2017 (FR8HUB) and the AWP 2018 (FR8RAIL II) as well as the relevant open calls.Within the challenges highlighted in the IP5 part of the S2R Master Plan, FR8RAIL III further focuses on improving the freighteco system by addressing various challenges in 6 different field: - Condition based maintenance- Real-time Network Management- Intelligent Video Gate Terminals- Extended Market Wagon- Telematics & Electrification- Freight Loco of the futureSummarizing, FR8RAIL III focuses on various facets of the freight eco system with one goal: overall improvement and increase of competitiveness of the rail freight transport.


**Keywords:** Wagon Design, Running Gears, Smart Assets, Electrification, Propulsion Systems,  Condition Based Maintenance
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Developing a new sensorimotor body representation for an additional robotic limb.' in the context of a Horizon Europe call.

assistant: **Objectives**

Adding an artificial body part could expand our motor abilities. But can our brain develop an integrated multisensory representation of an extra limb in addition to our own body? In BodyPlus, we will explore whether the brain can extend our body representation to incorporate an additional robotic thumb, known as the Third Thumb. We will compare participants’ behaviour and brain responses before and after a 4-day training period where they learn to control the Third Thumb. In Work Package 1 (WP1), we will use two behavioural paradigms to determine whether participants develop novel sensorimotor links through training. Specifically, we will examine whether participants learn to integrate touch location with posture, and sensory information with movement predictions. We will use computational modelling to identify behavioural biases indicative of optimal Bayesian integration. In WP2, we will scan participants using fMRI as they control the Third Thumb. We will compare conditions where the Thumb’s movement matches or doesn’t match the movements participants learned during training, allowing us to identify brain regions that integrate Third Thumb movement with sensory predictions. Furthermore, we will use brain decoding to determine if the newly acquired representation of the Third Thumb compares with the representation of participants' own right thumb, or of a familiar tool. In WP3, we will examine how participants behaviour changes when we remove key sensory inputs, which were available during motor training, or modify the expected movement of the Third Thumb. This will allow us to determine the resilience and generalisability of the newly formed Third Thumb representation. Overall, BodyPlus will identify the key components that the brain uses to develop a new body represe
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Great ape organoids to reconstruct uniquely human development', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Humans diverged from our closest living relatives, chimpanzees and other great apes, 6-10 million years ago. Since this divergence, our ancestors acquired genetic changes that enhanced cognition, altered metabolism, and endowed our species with an adaptive capacity to colonize the entire planet and reshape the biosphere. Through genome comparisons between modern humans, Neandertals, chimpanzees and other apes we have identified genetic changes that likely contribute to innovations in human metabolic and cognitive physiology. However, it has been difficult to assess the functional effects of these genetic changes due to the lack of cell culture systems that recapitulate great ape organ complexity. Human and chimpanzee pluripotent stem cells (PSCs) can self-organize into three-dimensional (3D) tissues that recapitulate the morphology, function, and genetic programs controlling organ development. Our vision is to use organoids to study the changes that set modern humans apart from our closest evolutionary relatives as well as all other organisms on the planet. In ANTHROPOID we will generate a great ape developmental cell atlas using cortex, liver, and small intestine organoids. We will use single-cell transcriptomics and chromatin accessibility to identify cell type-specific features of transcriptome divergence at cellular resolution. We will dissect enhancer evolution using single-cell genomic screens and ancestralize human cells to resurrect pre-human cellular phenotypes. ANTHROPOID utilizes quantitative and state-of-the-art methods to explore exciting high-risk questions at multiple branches of the modern human lineage. This project is a ground breaking starting point to replay evolution and tackle the ancient question of what makes us uniquely human?


**Keywords:** Si