RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'An integrated platform enabling Theranostic applications at the Point of Primary Care' to be submitted under Seventh Framework.

assistant: **Abstract**

TheraEDGE is an industry-driven effort to accelerate the adoption of theranostics applications in Primary Care by pushing Point of Care Test (POCT) technology far beyond its current state-of-the-art and by delivering clinical, analytical and operational breakthroughs.TheraEDGE is built around the high-incidence clinical case of early-diagnosing lower respiratory tract infections in Primary Care. Simultaneous testing for different pathogens and their antibiotic resistance will have a huge European impact:better clinical outcomes and standards of care through more effective and timely diagnosis and treatmentimproved health economics through optimization of antibiotics prescription, infection control practices and reduction of clinical visits or hospital stayssubstantial business for the In Vitro Diagnostics industry through the standardisation and commercialization of innovative POCT products and systemsTheraEDGE consists of three multidisciplinary platforms:a core Lab-On-a-Chip supporting multi-marker assays and using Single Molecule Detection (SMD) as an alternative to PCR-based molecular diagnostics. SMD removes the need for amplification and has the potential to become a key enabler for Nucleic Acid Testing at the Point of Care by providing less complex, faster, more sensitive and more specific assaysan architecture that provides Plug and Play semantic interoperability and creates opportunities for the standardisation of POCT instruments and information systems, offering radical usability, robustness and vendor interoperability improvements. Practitioners will be able to run out-of-the-box multiple compliant devices from one single PDA-based operator interfacea set of applications built on a convergent ITC platform that supports General Practitioners in their pa
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'New Heterocyclic Liquid Crystals' under Sixth Framework.

assistant: **Concept**

This proposal will bring to the EU a most talented Russian researcher with a strong background in heterocyclic chemistry, and to use his expertise in a ped with the synthesis and properties of new heterocyclic liquid crystals. In one part, the work will exploit the availability of precursors to symmetric and unsymmetric di- and tri-substituted phenanthrolines to realise high birefringence materials with negative dielectric anisotropy, while in another, bent-core disubstituted phenanthrolines will be obtained as shape-complementary, dipolar system.The third aspect of the project will employ new synthetic approaches to cyanopyridines developed by the applicant to realise new families of strongly dipolar liquid crystals. It should be noted that the use of a ph enanthroline core in new in liquid crystal systems and offers a number of attractive structural possibilities as outlined in the application. It is planned that the work carried out under this programme will form the basis for an ongoing collaboration between applicant and host once the fellowship is ended.The research area is highly topical as liquid crystals represents an area of real strength within the EU, and new generation displays are emerging based on EU-derived materials and technology. The host group is part of a major UK-based consortium on liquid crystal technology, and access to its meetings will develop a broad appreciation in the applicant of the true scope of this technologically crucial area.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Sixth Framework proposal for the project 'CONTENT4ALL - Cross-platform tools for community content publishing'.

assistant: **Objectives**

Imagine a scenario where personal, physical and time boundaries are weakened, new opportunities for the content community arise: producers, publishers and broadcasters can develop new forms of content programming, new storytelling formats and new business opportunities. Combination of emerging scenarios, such as media convergence" and "peer-to-peer", offers the ideal opportunity where sharing content between persons becomes possible independently of the used media. This offers an anytime, anywhere, anyhow, anybody paradigm of content consumption ideal for new collaborative affinity communities emergence as well as the promotion of new forms of collaborative story telling.Intelligent content publishing and moderation of peer-to-peer affinity communities offers new business opportunities. To exploit such opportunities, intelligent management tools and methodologies are needed. CONTENT4ALL (C4A), "Cross-platform Tool For Community Content Publishing" will provide a common service platform to share, communicate and manage content objects between broadcast, Internet and wireless. C4A leading objective is the development and consolidation of a coherent framework for competencies interoperability in the European Media full value chain taking advantage of the peer-to-peer phenomenon and emerging related opportunities. To do this, it will explore creation of a peer-to-peer cross-media intelligent content management model, based on an open source standards, where next-generation affinity communities can meet individuals' and organizations' needs.C4A will also provide business simulations of selected case studies to meet organizational, social and economic challenges raised by the emergence of the peer-to-peer collaborative networking phenomenon in a cross-media environment."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Construction of miniaturised free flow electrophoresis (mffe) incorporating dedicated sensors for real-time analysis of food contaminants' (MICROSENSOR).

assistant: **Innovation**

Food safety and quality are fundamental obligation towards the European consumer as clearly identified in the proposal Agenda 2000" towards of the Common Agricultural Policy. The consumer and authorities are concerned about the problem of food safety (e.g. microbiological and chemical contamination), and environmental issues (e.g. animal welfare). The major objective of MICROSENSOR project is to develop and demonstrate the practical feasibility of miniaturised free flow electrophoresis (FREE) -based optical biosensor techniques for real-time measurement of analysts (e.g. markers of rBST hormone and Listeria), as a generic tool to address the problem of food safety. If successful, the new analytical technology will enhance:(i) food safety by providing efficient tools to cope with modern food production, and(ii) efficiency of European Food Control laboratories."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'The First In Vitro Diagnostic Device for the Early Detection of Cardiac Ischemia', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Cardiovascular diseases (CVD) are the leading cause of death/morbidity across the globe, accounting for 31% of all deaths in 2015. In the same year almost 49 m Europeans were living with CVD. Early detection of ischemia is essential to prevent the progression of heart damage and the irreversible tissue damage (necrosis) that can lead to heart failure.AGLYC is an IVD lab-based test for the early detection of ischemia (15 mins event onset) in the absence of the irreversible necrosis of the tissue. AGLYC demonstrates a 98% sensitivity in detecting the presence of ischemic heart disease. Our main competitive advantages are high sensitivity, early detection of ischemia, and cost effectiveness. The global in vitro diagnostics (IVD) market was valued at $64.02 bn in 2017 and is projected to reach $87.93 bn by 2023, at a CAGR of 5.2%. The laboratory diagnostic test (lab-based) market represents 86% of the total diagnostic testing market. Specifically, the market for lab tests related to acute cardiac ischemic events represented about $166 m in total sales in 2015. We have estimated a lab-based target market of >70 m patients.Our main business model will be a sublicense model based on the development of a laboratory-based test that we will develop and then sublicense to either a medical device company (MedTech) or to a pharmaceutical company. With this model and the successful completion of the SMEI phase 2 we estimate an EBITDA of around €23 m.The company closed a first funding round of €2.4 m on October 2017 to cover nearly 65% of the expenses of the development plan. GlyCardial Diagnostics, S.L. was founded in 2017 as a spin-off of the ICCC- IR-Hospital de la Santa Creu i Sant Pau and the Spanish National Research Council with the focus of developing a novel IVD test for card
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'DEsign, development, manufacture, testing and Flight qualification of nExt geNeration fuel storage system with aDvanced intEgRated gauging and self-sealing capabilities' (DEFENDER) under Horizon 2020.

assistant: **Objectives**

The DEFENDER project is aimed at developing, manufacturing, testing, and qualifying innovative next generation fuel storage system with advanced integrated gauging, self-sealing capabilities and high performing closed cells foams to be integrated into the Next Generation Civil Tiltrotor (NextGenCTR) framed in the Fast Rotorcraft (FRC) Innovative Aircraft Demonstrator Platform (IADP). As integral part of the whole activity, the consortium will support the WAL in all the activities related to the Permit to Fly achievement and will provide technical support during the installation of the lightweight bladder tanks in the aircraft prototype and during flight testing. The first step will consist in a specification review and preliminary system design activity and a technological study, both aimed at full design of fuel system and assessing the effectiveness of the proposed innovations. In particular, the fuel storage subsystem (FSS) shall be capable of storing fuel and providing a sufficient mechanical resistance against punctures and impacts avoiding any leaks.  The Fuel System architecture will be used to drive the next detail design phase. Starting from the requirements, the specification of the interfaces and the digital mock-up, the DEFENDER consortium will proceed with the design and analysis, maximising low weight and safety, fully compliant with the Rules requirements and WAL Requirements. The manufacturing of the FSS will be carried out according to the EASA Part 21 subpart G (POA). Design and qualification will be performed on the strong heritage of the consortium in the development and qualification of aeronautical/military/automotive/marine fuel storage system. The project consortium, made of 2 SMEs, the Italian Aerospace Research Centre (CIRA) and an academic cen
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'The carbon sink strength of beech in a changing environment: experimental risk assessment of mitigation by chronic ozone impact.' to be submitted under Fifth Framework.

assistant: **Abstract**

The vulnerability of adult beech is to be clarified at Central-European forest conditions to chronic O3 impact. O3 as acting in Global Change" may constrain the C sink strength under expected atmospheric CO2 enrichment. A novel "Free-Air Canopy O3 Exposure" system, creating an enhanced O3 regime within the canopy ensures the analysis of O3-induced responses relevant for tree C balance. O3 flux into leaves will be validated against AOT40. Responses across cell, organ and whole-tree level will be assessed with molecular, biochemical and ecophysiological methods. Additional exposure of young beech within the canopy and branch curette fumigations will validate previous O3 studies. Evidence will be incorporated into mechanistic modelling that scales to the stand level and quantifies O3 impact for "Global Change" scenarios. This process-based risk assessment will guide policy making."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Imaging magnetic fields at the nanoscale with a single spin microscope' (IMAGINE), addressing dissemination and exploitation.

assistant: **Impact**

Detecting and imaging magnetic fields with high sensitivity and nanoscale resolution is a topic of crucial importance for a wealth of research domains, from material science, to mesoscopic physics, and life sciences. This is obviously also a key requirement for fundamental studies in nanomagnetism and the design of innovative magnetic materials with tailored properties for applications in spintronics. Although a remarkable number of magnetic microscopy techniques have been developed over the last decades, imaging magnetism at the nanoscale remains a challenging task.It was recently realized that the experimental methods allowing for the detection of single spins in the solid-state, which were initially developed for quantum information science, open new avenues for high sensitivity magnetometry. In that spirit, it was recently proposed to use the electronic spin of a single nitrogen-vacancy (NV) defect in diamond as a nanoscale quantum sensor for scanning probe magnetometry. This approach promises significant advances in magnetic imaging since it provides quantitative and vectorial magnetic field measurements, with an unprecedented combination of spatial resolution and magnetic sensitivity, even under ambient conditions.The IMAGINE project intend to exploit the unique performances of scanning-NV magnetometry to achieve major breakthroughs in nanomagnetism. We will first explore the structure of domain walls and individual skyrmions in ultrathin magnetic wires, which both promise disruptive applications in spintronics. This will lead  (i) to solve an important academic debate regarding the inner structure of domain walls and (ii) to the first detection of individual skyrmions in ultrathin magnetic wire under ambient conditions. This might result in a new paradigm for spi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Synthesis and Evaluation of 18F-Labelled N-F Reagents' (SELEFLU).

assistant: **Innovation**

The overall objective of this proposal is to capitalise on our expertise in synthetic and fluorine organic chemistry by undertaking a research programme aimed at exploring the value of 18F-labelled N-F reagents. Upon completion of the proposed research programme, we hope to provide 18F-radiochemists with a toolbox filled with novel 18F-radiosynthetic strategies. The unconventional and innovative methods that we will investigate are designed to address well recognised pending problems in 18F-radiolabelling and to offer unprecedented radiosynthetic routes to access 18F-labelled targets.  The impact of the novel radiochemistry we propose to develop is far reaching to advance Positron Emission Tomography (PET). PET is a non-invasive molecular imaging technique used clinically for diagnostic purpose and drug discovery.  This expanding highly interdisciplinary area of research relies on radiotracers labelled with a positron-emitting radioisotope.  18F-Labelled molecules are frequently used because of the advantageous properties of the 18F in comparison with other non-metallic radioisotopes. For rapid progress, the radiochemistry available for 18F-labelling should be sufficiently diverse for any designed 18F-radiotracers to be accessible regardless of the point of attachment of the 18F-label. To date, this is far from the reality, as current methodologies to construct 18F-labelled molecules present with limitations. The emphasis of this proposal is on the development and use of 18F-labelled N-F reagents of high specific activity for electrophilic fluorination.  These reagents should allow for the production of 18F-labelled radiotracers in high radiochemical yield, purity and specific activity.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'EMBL PhD Student Symposium on Evolution' (1998-2002) targeting Fifth Framework.

assistant: **Abstract**

Being young researchers themselves, the organizers of the EMBL PhD Student Symposium on Evolution recognize the need for a meeting that is accessible both to specialists in evolutionary biology and to non-specialists alike. Evolution is the underlying principle that unifies all disciplines within the life sciences. An appreciation of evolutionary theories and an understanding of the latest research developments in this field are of great benefit to biological scientists. As the future generation of international scientists, young researchers in particular should be exposed to the subject. The proposed symposium aims to provide the opportunity for young scientists to interact with those well-established researchers, working at the cutting edge in the field. During the two-day symposium, thirteen leading scientists whose interests cover six areas (detailed below) will each present a lecture.The focus of the symposium will be largely on molecular evolution, supplemented with lectures exploring for example cultural evolution and the application of evolutionary theories to artificial systems. The research backgrounds of the invited speakers are diverse, spanning developmental biology, phylogenetics, structural biology, population genetics and palaeontology. Equally, the participants are anticipated to be drawn from a range of biological disciplines. The multidisciplinary nature of the meeting, inherent in the subject itself, should promote a high level of discussion and strengthen the network of European scientists concerned with evolutionary biology. EMBL, an institute housing some of the leading research activities in Europe, will be the location for this symposium. The international flavour and open, highly collaborative nature of the institute will promote interactions b
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'Voltammetry under high mass transpor conditions'.

assistant: **Objectives**

The improvement of electrochemical techniques using High Speed Channel Electrodes (HSCE) recently introduced by Compton et al, and their application in combination with spectroscopic methods 'in situ' to study electroorganic reactions is pursued.  The HSCE methods allow the determination of rate constants of fast electrode reactions usually masked by the mass transport. The technique is also suitable to identify the nature of the short-time living intermediates in electrode mechanisms when combined with spectroscopic techniques. The HSCE will be applied to mechanistic problems related to electrode reactions of some organic compounds in which both the group in Oxford and in Seville are interested. First the oxidation of ferrocene will be studied preventing the formation of passivating overlayers. Then, the method will be adapted for photoelectrochemical measurements in order to study the fast light induced decomposition of electrogenerated radical anions of halonitrobenzenes. The analysis of the first electron transfer in the reduction of nitromethane and the characterization of the radical formed will be attempted combining HSCE with ESR and UV spectroscopies 'in situ'.