RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'sCalablE iNnovaTive pRocessEs for the ProductIon of fuEl CElls' under Horizon Europe.

assistant: **Concept**

PEMFCs are expected to increase their share of the transport market over the next years, but to do so MEA manufacturing processes and technologies must become more reliable, efficient and faster to allow lower cost. Therefore, it is key to implement advanced manufacturing techniques for catalyst coated components, which will enable lower raw materials consumption, lesser cost and reduced waste by applying innovative printing and coating techniques.Although low-volume batch processes have transitioned to roll-to-roll production lines, there is still a need for higher line speeds and yields, since the main materials are all relatively expensive (membrane, ionomer, PGM-based catalysts). In addition, conventional CCMs usually do not allow an easy recyclability, therefore generating the need of new industrial processes. CENTREPIECE will, 1) upscale and validate with up-to-date CCM materials using innovative coating techniques developed in previous projects, with the objective of making them suitable for large-scale production [TRL6] 2) Develop and validate In-line Quality Control techniques against ex-situ and off-line data [TRL6] 3) integrate project developments into a prototype pilot line capable of 2400 m2/year at a line speed >10m/min [MRL5] 4) Revolutionary digital coating and laser drying technology will also be assessed. MEAs will be manufactured full size (280 cm2 active area) and benchmarked against conventionally manufactured, showcasing the ability of the line to meet industrial needs, whilst decreasing the scrap-rate below 5% and increasing the yield to >90%.CENTREPIECE will build on the developments from previous projects (MAMA-MEA, CAMELOT, VOLUMETRIQ, INSPIRE, IMMORTAL, HIGHLANDER, etc.). Innovative techniques, together with in-line QC processes will allow hi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Seeing and Being Seen: Representation in Proportional Systems' (SEE).

assistant: **Innovation**

Political representation links geography and citizens’ voices. In recent years, citizens have used their voices to channel their grievances about being left behind. Events such as Trump’s election, Brexit, the French Yellow Vests, and the rise of extreme-right across Europe motivated researchers to investigate the causes and consequences of geographic divides in contemporary democracies.However, most theoretical frameworks examining the interplay between geography and representation are rooted in the political, economic, historical, and sociological experience of the United States. Unlike the U.S., most European democracies employ proportional electoral systems, have strong political parties, stronger redistributive politics, and different urban organizations. Cities are denser, less segregated, and have more public transportation.The primary motivation for this project is to break new ground by developing a theoretical framework grounded on the institutional, socioeconomic, and historical trajectories of proportional European democracies. I analyze representation at the level it takes place: the electoral district. The complexity of electoral districts in European proportional democracies forces legislators into difficult trade-offs. SEE will (1) map representation inequalities inside electoral districts; (2) understand legislators' choices based on their preferences, biases, and partisan constraints; (3) identify and analyze the implications of legislators’ choices on citizens’ attitudes and reactions to representation; (4) create a theoretical and empirical framework to examine representation in the suburbs.SEE will use a comparative and integrative multi-method approach to meet its goals with a sequential integration of cross-sectional observational data, elite and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'ADDitively Manufactured OPTimized Structures by means of Machine Learning' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Additive Manufacturing (AM) has attracted the interest of industry due to its potential for flexible and automated production of complex geometry objects, combined with minimizing the time required to develop new products. According to recent analysis, the market for AM products is projected to grow annually by 18%. Although AM technologies are an integral part of digitized industrial production and of the 4th industrial revolution, Architectural, Engineering & Construction Industry (AECI) is reluctant to adopt them in design and construction. While AECI has been a pillar industry since 80's, its scale and impact on the global economy expands continuously. This development is also associated with important drawbacks, including large contribution to waste production, huge energy consumption and severe environmental pollution. The recent Green New Deal for Europe sets as primary objective the reform of heavy industry, including AECI, which accounts for 40% of the energy consumed on the continent. The main tools for achieving this objective are to minimize both materials used and amount of AECI waste. The principal aim of ADDOPTML network is to create and validate a holistic machine learning aided, optimum design-manufacturing process of civil structures by developing strong synergies among a multi-disciplinary team of academic experts and SMEs from Belgium, Bulgaria, Cyprus, Germany, Greece, Italy, Jordan and Spain. This will be achieved by taking advantage of ongoing progress in AM technologies including recycled consumables, thus contributing to the European challenge to become the world's first climate-neutral bloc by 2050. As a primary application, an integrated structural design framework based on AM optimized structural elements for transitional structures will be d
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Resource management in Karstic areas of the coastal regions of the Mediterranean' (1994-1998), addressing dissemination and exploitation.

assistant: **Impact**

* To produce an inventory of environmental resources for selected coastal karstic regions of Malta, Turkey and Lebanon.* To identify the institutional structures in these countries and carry out comparative analysis and evaluation of policies for resources management.* Devise integrative methodologies, based on information management tools such as GIS and remote sensing, and to validate these for the selected study areas.* Formulate sustainable resource management strategies, that can be used to respond effectively to identified development needs.Expected OutcomeThe project should provide a generic methodology (a guidebook) which can be used to devise decision making tools for coastal karstic areas. A software product which can be used to simulate different scenarios will be produced for the study areas. This will be used to demonstrate what can be achieved with the methodology.The methodology will be of use to planners and administrators as a way to devise strategies which aim to allow development in coastal karstic areas, whilst preserving the karst massif and the resources associated with it.* Bibliographic studies to provide an assessment and of the structure and roles of various institutional organisations which have responsibility for resource management in the areas and interviews to identify planning policies within each country. A comparison will then be drawn between the countries.* Field studies and bibliographic studies to establish an inventory of resources, an assessment of the state of the resources, their importance and the vulnerability of the resources.* Bibliographic and field studies, and interviews to determine the environmental problems facing the karst massifs in each of the areas.* Research to identify the relationships between the various resour
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Climate Change, Water and Productivity in the Mediterranean: Capacity Building for Geospatial Modelling'.

assistant: **Objectives**

The aim of this research is capacity building through exchanging young scientist to estimate both hydrological and rates of biogeochemical cycling in order to test hypotheses on the relationship between climate change and ecosystem productivity in the Mediterranean environment. Remotely sensed-data, GIS and process-based simulation models have provided the capability to assess ecological change at broad spatio-temporal scales. The proposed exchange programme can be considered as a chance of connecting the hydrology and the remote sensing communities from Europe and US to develop tools for understanding of climate change consequences using geospatial technologies. The requested EU exchange project pursues a clear application and enables to transfer expertise from science into practice and on the other hand the mutual exchange of knowledge between research groups from Turkey, Germany, England and US. The major focus of the project using geospatial technologies is in two folds: i) Climate change and water management and modelling; Water scarcity and management is a cross-cutting issue in the world. This is especially true in the Mediterranean region where water resources are limited and water issues are the most urgent. Modelling the water, solute and erosion dynamics will be done by means of the J2000 physically based system which will be supported by GIS-analysis and remote sensing; ii) Climate change and the ecosystem productivity; The main steps are, a) Classification, quantification and analysis of land-use, b) Collection of inputs (climate, soil and biotic data) for simulation models, c) Quantification of C-N budgets and simulation of temperature rise scenarios. These topics are interdisciplinary in nature and involve processes that are relevant to biophysical ecolog
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Improved immunity of aquacultured animals' goes beyond current state-of-the-art under Sixth Framework.

assistant: **Innovation**

Based on important disease models, this project concerns development of a technological knowledge platform for a future improved immunity to infectious pathogens in the major aquacultured species in Europe (Atlantic salmon, rainbow trout, sea bream, sea bass, carp, mussel and oyster). Focus will be put on use of vaccines, immuno-stimulants, immuno-diagnostic surveilance as well as markers for selection of the most immuno-competent individuals. Assays for qualitative and quantitative monitoring of key elements of the innate and adaptive immune system at genetic and functional levels will be established and used for determination of response profiles which correlate with protective immunity. For all species, infection trials with various types of pathogens, including re-challenge of survivors, will be used to determine reference response profiles of nave and primed animals. For finfish, vaccination trials with efficiently working commercial and experimental vaccines and corresponding control reagents will be used to identify critical response elements/profiles for vaccine efficacy. Variability both in terms of gene polymorphism and occurrence of isoforms among the immunological key elements and their regulation will be related to the functional response in in vitro assays as well as in vivo in terms of disease susceptibility of nave and primed/vaccinated animals. Assays for direct functional determination of gene functions will also be developed. The outcome of the project will be versatile gene array and immune response assays which can be implemented in development of efficient vaccines and immuno-stimulants for the finfish species and for genetic typing, monitoring of immuno-competence and immuno-diagnostic surveillance in both finfish and shellfish. In combination wit
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'A Cross-Species Investigation of Memory Replay During Reconsolidation' in the context of a Horizon 2020 call.

assistant: **Objectives**

A primary treatment for anxiety disorders is exposure therapy, which is based on the principles of extinction, but has the drawback that fear can return. This risk of relapse highlights a need for treatments that persist. Research on reconsolidation has shown that upon reactivation old fear memories can be updated, preventing the return of fear. However, studies targeting reconsolidation to reduce fear have reported mixed results because its boundary conditions are poorly understood. To live up to its clinical potential it is necessary to understand how to most effectively utilize paradigms targeting reconsolidation. The proposed research attempts to address this issue by providing a neural measure of the reconsolidation process itself. This will be achieved by determining whether dynamic patterns of neural network activity that occur during initial learning re-occur during offline ‘rest’ periods, and test whether this ‘replay’ of memory is linked to reconsolidation. The first objective of this grant application is to identify and quantify a neural marker of reconsolidation that predicts the absence of fear recovery.  During the outgoing phase these questions will be addressed employing an innovative cross-species (humans, rats) approach using similar behavioural tasks, complementary recording techniques (functional magnetic resonance imaging, multi-unit recordings) and state-of-the-art analyses methods. Acquired knowledge and experience will be applied during the return phase where the second objective is to use this neural marker to determine how context serves as one critical boundary condition to inducing reconsolidation. Findings will significantly advance fundamental understanding of reconsolidation and have important implication for applied and preclinical psychi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Source apportionment of airborne particulate matter and polycyclic aromatic hydrocarbons in urban regions of europe' (SAPPHIRE) targeting Fifth Framework.

assistant: **Abstract**

Atmospheric particles and their individual chemical constituents (including PAH) have demonstrably significant social and economic impacts through adverse effects on human health and environmental quality. Effective control of these pollutants requires detailed knowledge of the relative contribution of their sources in order that action to reduce emissions can be most effectively targeted. Our overall objective is to develop and validate a readily transferable common methodological approach to source apportionment of atmospheric pollution that will be utilised by local city governments, thereby assisting in improving air quality in the cities of Europe. It will generate a technical report and accompanying user-friendly customised software package for data analysis that is designed to facilitate the widest possible use of the methodology across Europe by local authorities.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Sixth Framework proposal on 'Design, synthesis and characterisation of Conotoxins'.

assistant: **Concept**

This project aims at the development of novel strategies for the Design, Synthesis and Characterisation of Conotoxins (DSCC). Conotoxins form a large family of peptide toxins from cone snail venoms that act on a broad spectrum of ion channels and receptors.The subgroup a-conotoxins specifically and selectively bind to subtypes of nicotinic acetylcholine receptors 8nAchRs), which are targets for treatment of several neurological disorders.The development of synthetic strategies for conotoxins and derivatives are essential to efficiently approach important questions within the area of neurobiology and to meet the need for novel drugs with new mechanisms of action useful in treatments for important diseases such as chronic pain and Parkinson disease.The EIF will receive advanced training in the S and T competences necessary to perform high-level research and to generate new knowledge on synthesis of conotoxins. The EIF will carry out his project in an exciting, active and dynamic research environment.His project will focus on achieving the following ambitious scientific objectives:- Development of new synthetic strategies for generation of conotoxin and derivatives- Development of state-of-the-art methods for design, synthesis, characterisation and application of such compounds- To examine fundamental aspects of the design and synthesis of conotoxin derivatives in order to provide a greater understanding of what parameters govern the biological function of the compounds.The main training objectives of this research-training project are:- Providing advanced training tailored the EIF to needs with a view to adding different/complementary scientific competencies in organic chemistry, structural biology and pharmacology- To enhance both the EIF research capacities and compleme
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'From fluid dynamics to quantum gravity' in the context of a Horizon 2020 call.

assistant: **Objectives**

Reconciling general relativity with quantum physics is the Holy Grail of theoretical physics. Today the major physical predictions involving both gravity and quantum fields, in the framework of quantum field theory in curved space-times, are black hole radiation and particle production in an expanding Universe. These phenomena are the corner stones of our present knowledge about the quantum nature of space-time, and it is of crucial importance to understand deeply their features and consequences in the quest for a quantum theory of gravity. Unfortunately, these features are still poorly understood, and are experimentally out of reach in astrophysics. This project will bring together an experienced researcher with expertise in Hawking radiation and black hole physics, with a world leader physicist in artificial space-times in fluid flows to tackle these questions in the innovative approach of analog gravity. Unlike in astrophysics, artificial black holes can be experimentally realized using fluids, showing both their classical and quantum properties. Because these fluids are well understood, both experimentally and theoretically, many conceptual questions can be explicitly addressed in such systems. By working in a world-leading group in the field at the University of Nottingham, the local expertise and mine will be the perfect match to tackle these questions.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Tracing the Intracellular Fate of Anticancer Nanomedicines', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Nanomedicines are defined as specifically engineered, nanosized drugs and drug delivery systems that are comprised of multiple components. For example, polymer-drug conjugates and drug-protein conjugates are emerging as promising approaches to treating a number of diseases, including cancer. The payloads of these nanomedicines differ widely. However, when targeting cancer, there is a universal requirement to reach the tumour microenvironment and often to deliver the payload to a specific intracellular compartment in order to yield the desired therapeutic effect. The goal of this proposal is to develop two complementary approaches that showcase the manufacturing of functionalised biopolymer-based nanoparticles and their subsequent biological evaluation in relation to cellular and subcellular trafficking in the tumour microenvironment. To achieve this goal, I propose two main aims. Aim 1 is to generate drug-loaded silk nanoparticles that can be readily functionlised to target specific cells and cellular compartments. I hypothesise that by using functionalised silk nanoparticles, it will be possible to target and deliver a therapeutic payload to cancer cells, which will lead to improved clinical outcomes in vivo. Aim 2 is to establish a repertoire of subcellular fractionation techniques in order to quantitatively describe the intracellular fate of nanomedicines in vitro and in vivo. I hypothesise that in particular, subcellular fractionation methods will allow a better understating of the fate of nanoparticles in tumour cells and their subsequent intracellular trafficking. Taken together, these studies will demonstrate an integrated approach to the development of next-generation nanomedicines. This proposal provides the drug delivery field with a novel nanoparticle system