RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Using antisense inhibition to understand Wolbachia symbiosis and antiviral protection' (WolAntiS) targeting Horizon 2020.

assistant: **Abstract**

Wolbachia is a widespread, intracellular symbiont of arthropods and filarial nematodes, inducing reproductive distortions and antiviral protection in insects. Wolbachia is currently being deployed in disease vector control programs and is also a target in the treatment of lymphatic filariasis. Despite its prevalence, fascinating phenotypes, and applied importance, Wolbachia biology remains poorly explored, as it cannot be cultured or genetically manipulated. To date, antisense RNA and a transfection reagent that knock down Wolbachia gene expression have been deployed in cell culture, but the effect was modest and likely very transient. In order to achieve a robust and lasting antisense inhibition in Wolbachia, applicable in an in vivo system, I will utilize developments from drug delivery and gene manipulation in other members of the Rickettsiales. This will involve the use of nuclease resistant nucleic acid analogs, which can strongly inhibit transcripts for many days. This technology will be combined with attachment to different transporter molecules, known to deliver nucleic acids to other intracellular bacteria and parasites within host cells and organisms. I will then use this system to interrogate the genes putatively involved in host-microbe interactions in cell culture. I will focus on genes underlying symbiosis and those directly conferring the trait of antiviral resistance. The technology created will be widely applicable in studies of host-symbiont interactions, and in determining the mechanisms underlying the diverse phenotypes and symbioses observed. This project will thus both enable discovery science and allow better human disease prevention and treatment.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Human-centric Intelligent LED engines for the take up of SSL in Europe' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

The HILED project will advance the state of the art of Solid State Lighting (SSL) through research on innovative light engines that take advantage of full control of light. The incorporated intelligence enables responsive fine tuning of spectral properties in real time, as well as precise dimming capabilities. These smart engines with added intelligence offer natural illumination patterns that respect our biological circadian rhythms. This can be done very accurately by spectral selection or even through Correlated Colour Temperature (CCT) adaptation by using the most efficient combination of  white LEDs, coloured LEDs, and OLEDs as building blocks of the light source, while satisfying different constraints on energy efficiency. Markets such as horticulture and greenhouses would also benefit from fully controllable light engines, whose spectral content can be dynamically adapted to the plant needs in real time, through the establishment of algorithmic strategies and feed-back systems that control the growth process. Besides the spectral effects on leaf photosynthesis there are more important spectral effects on morphology and development of plants. Morphological effects directly influence the ornamental value of cut flowers and pot plants and therefore their economic value. Furthermore, these morphological effects may strongly influence the growth rate of the plants. Last but not least the choice for light spectrum may affect the production of secondary metabolites. These metabolites can have human health promoting effects (e.g. anti-oxidants, vitamins, etc).Additionally, these light engines are particularly well suited for museum lighting, where careful selection of spectral content may achieve an  optimal balance between energy efficiency, quality of light and art con
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fourth Framework proposal on 'INCREASE OF PERFORMANCE OF NATURAL REGROWING OILS TO LUBRICATE EARTH-MOVING EQUIPMENTS'.

assistant: **Innovation**

Lubricants are of major importance to improve lifetime an energy efficiency of engines, machines or industrial processes etc., and to reduce friction and wear. Thus, lubricants have to fulfil different and increasing technical and environmental requirements. During the last years different types of biodegradable lubricants have been developed mainly based on synthetic esters and natural materials like rapeseed oil. Till now the use of biodegradable lubricants is very limited because technical requirements which have to be normally fulfilled could only be achieved by using biodegradable synthetic oils; 6 times more expensive than the traditional used mineral oils, which proved to be prohibitive for many applications as e.g. in earthmoving machines where a normal tank can contain 0.8 Tonnes of oil. An economic alternative of these oils are vegetable oils. But up to the moment the experience of the Machine Manufacturers and the COST/Renewable environmentally friendly lubricants group of Tribology, with rapeseed based hydraulic oils have the following drawbacks : time dependence of viscosity at low temperatures, hydrolytic and oxidation stability problems and difficulties when filtering. Thus limiting their usage to those application, where only lower technical performance is requested. Due to this end users are reluctant to use these products.A wider use of biodegradable lubricants could be achieved by using new base stocks from industrial crops, biological and chemically improving vegetable oils decreasing the content of non stable products in order to improve the rheologic behaviour of actual rapeseed oils, its oxidation and hydrolytic stability (by factor of 10), and decrease the actual limit of temperature of the machines, unless up to -26 C avoiding nucleation of para
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Innovative Portable Traction Ramp from Smart Composite materials for Automatic Ascending and Descending of Wheelchair Users' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

The RampCo is a technologically advanced folding ramp, for automatic ascending and descending of wheelchair users, thus paving the way to Universal Accessibility in buildings and public spaces. RampCo is a portable ramp that can be automatically packed in the form of an all-in-one transport case and can be transferred easily and quickly by hand. RampCo will have a lightweight design due to the use of smart composite materials that will ensure the best strength/weight ratio.The RampCo, on the wheelchair user’s command, will transport the wheelchair safely several meters all the way up the stairs, without any assistance. The RampCo will operate on slopes beyond the typical 8% (5deg angle) reaching and up to 60% (30deg angle). RampCo will be a revolutionary product in the ramp market since no other portable, foldable, extendable device exists worldwide with this feature. RampCo will be able to climb all sorts of straight stairs up to a slope of 60%. It will allow the wheelchair user to safely ascent to elevations from 50 cm (3 stairs steps) up to 140 cm (8 stairs steps). RampCo will be designed and developed in order to provide a safe accessibility solution for manually pushed and motorised wheelchairs in various kind of stairs (concrete based, glass, metal). RampCo will provide operation and navigation information to the wheelchair users, through Bluetooth technology and will allow remote access by the installer using a developed mobile application for monitoring and controlling in case of functional problems.The RampCo could have a massive uptake to serve a practically infinite number of cases with a difference in elevation, which are currently left inaccessible or are serviced in a poor way, with no provision for use by disabled citizens without assistance and more ofte
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fifth Framework proposal for the project 'Integrated software for health, transport efficiency and artistic heritage recovery (ISHTAR)'.

assistant: **Objectives**

The aim of ISHTAR Project is to build an advanced software suite for the analysis of the effects of short-term actions and long-term policies to improve the quality of the environment, citizens health, conservation of monuments. The activities will start and conclude in the 8 involved cities, and will be a continuous open gate to all the European cities interested in ISHTAR activities. The measures to be tested on the field and modelled with the suite will be defined by the cities, the first users of the results. The suite will include both existing and newly developed models, covering the areas of citizens behaviour, transport, vehicles emissions noise and safety, pollutants dispersion, house heating emissions, health, monuments degradation. These will find integration in the use of a GIS and of user-friendly integration software. The result will be the building and application to real cases of an innovative tool for urban management.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'ADvanced Aeroacoustic Processing Techniques', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Airbus is currently conducting various experimental studies, dealing with installing microphones on the fuselage, on the wall of a wind tunnel test section or on specific microphone supports on the flow, in order to record the sounds emitted by each aircraft component (i.e. engine, wing etc.). In either case, microphone measurements are polluted by hydrodynamic noise, which hampers the correct assessment of acoustic signals emitted from aircraft components, thus leading to very low signal-to-noise ratio.A few methods exist today that can eliminate hydrodynamic noise from acoustic signals. However, the efficacy  of these methods strongly depends on various parameters, such as signal-to-noise-ratio, number of microphones, number of incoherent sources etc. No systematic study has been performed so far to assess the parameter boundaries within which acceptable results are obtained (e.g. within 0.5 dB error for example).The ADAPT consortium will improve and optimize the ability of identifying sources emitted by aircraft components by using the most effective techniques out of the three proposed approaches in the call for proposal. These three approaches are: aeroacoustic source separation, de-noising techniques based on cyclostationarity and aeroacoustic sources localization.Through these three approaches, the ADAPT project aims at delivering to AIRBUS a tool dedicated to separating airframe and engine noise components (tonal, broadband cyclostationary components in particular) from hydrodynamic pressure noise and identifying these sources in space, satisfying various technical and economical requirements that will be discussed out with AIRBUS at the beginning of the project.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Market uptake of Solar Thermal Electricity through Cooperation', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

IIn the light of the EU 2030 Climate and Energy framework, MUSTEC aims to explore and propose concrete solutions to overcome the various factors that hinder the deployment of concentrated solar power (CSP) projects in Southern Europe capable of supplying renewable electricity on demand to Central and Northern European countries. To do so, the project will analyze the drivers and barriers to CSP deployment and renewable energy (RE) cooperation in Europe, identify future CSP cooperation opportunities and will propose a set of concrete measures to unlock the existing potential. To achieve these objectives, MUSTEC will build on the experience and knowledge generated around the cooperation mechanisms and CSP industry developments building on concrete CSP case studies. Thereby we will consider the present and future European energy market design and policies as well as the value of CSP at electricity markets and related economic and environmental benefits. In this respect, MUSTEC combines a dedicated, comprehensive and multi-disciplinary analysis of past, present and future CSP cooperation opportunities with a constant engagement and consultation with policy makers and market participants. This will be achieved through an intense and continuous stakeholder dialogue and by establishing a tailor-made knowledge sharing network. The MUSTEC consortium consists of nine renowned institutions from six European countries and includes many of the most prolific researchers in the European energy policy community, with very long track records of research in European and nationally funded energy policy research projects.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Identification of p38 MAPK partners in  the response of endothelium to oxidative stress and ionizing radiation. Impact in cancer radiotherapy'.

assistant: **Innovation**

Cancer is a leading cause of death in Europe. Therefore, improving the efficacy of curative treatments remains a major goal to achieve. Today, with more than 60% of European cancer patients treated with radiotherapy, understanding the biology underlying the cellular response to ionizing radiation (IR) is an ongoing challenge to ameliorate efficacy of this treatment. Basic concepts in tumor radiobiology have evolved. Endothelium irrigating tissues exposed to radiation and signaling events initiated at the plasma membrane are now considered as key issues. Thus, the membrane sphingolipid ceramide, reactive oxygen species (ROS) and importantly p38 MAPK proteins have been identified as critical molecular actors of the membrane initiated-response of the endothelium to IR.This project aims at characterizing the p38 MAPK pathway in the response of tumor endothelium to oxidative stress/IR and will address the following issues: What are the partners of p38 MAPK (p38-Partns) in IR/oxidative stress/ceramide pathway? Which IR-endothelial dysfunctions are associated with this p38 MAPK/p38-Partns pathway? The outgoing phase will characterize the ceramide/p38 MAPK pathway in endothelial cells exposed to oxidative stress. The methodological approach will rely on mass spectroscopy identification of p38-Partns. Role of p38-Partns in endothelial functions, notably in cell migration and adhesion by supra-resolution TIRF microscopy, will then be investigated. The return phase will explore this p38 MAPK pathway in vitro in endothelium exposed to IR and in vivo in human samples of irradiated tumor microenvironment.This project will yield new insights in life sciences from fundamental radiobiology and oxidative stress biology to identification of potential new targets for improvement of radioth
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Tools for Innovative Product-Service-Systems for Global Tool and Die Networks' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Europe's tooling industry takes up key a position within the production industries of Europe and all other IMS countries as studies have shown. Each production ramp-up depends on the completion of the required tools and their integration into the existing production facilities, the product’s quality is directly linked to the tool’s quality.  The tooling industry is facing challenges concerning their local and global performance. Regarding their local performance, there are no adequate interfaces and sporadic, undefined loops between the customers’ product development process and the toolmakers’ tool development process. Only few toolmakers offer product-services along the product development process, hardly any offer product-services along the production phase. Regarding their global performance only a little number of European toolmakers uses global cost potentials, markets and flexibility: they don’t realise the chances of globalisation.   As a result tool and die companies face the question on how to meet the customer’s needs at best locally and globally in order to remain competitive. Ideal solutions to the customer’s problems instead of a ‘simple’ tool can be developed by an early integration of product and tool development processes. Global cooperation offers chances to sustainably improve their position in this fierce competitive environment.   With this project European toolmakers are given tools to improve their local and global performance. These tools allow synchronising their tool development/ design with the customers’ product development processes by means of a continuous simultaneous engineering. The time-to-market of the final product can thus be shortened. Secondly this project shall enable European toolmakers to build global cooperation networks and ma
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Structure, reactivity and thermodynamics of bioinorganic and related systems', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

MC Training Site: Structure, reactivity and thermodynamic of bioinorganic and related systems Faculty of Chemistry, University of Wroclaw, located in picturesque old town offers trainings for the foreign PhD students in the area of organometallic, bioinorganic and coordination chemistry. In biological chemistry area the main topics are molecular mechanisms of metal toxicity and carcinogenicity; drug transport by serum proteins, metallo-protein engineering; new strategies in metal chelation, structure and thermodynamics of bioinorganic systems, etc. In inorganic chemistry, structure of coordination compounds and intermolecular interactions our expertise concerns application of the IR, NIR, thin film FT -IR, Raman, UV-Vis, NMR, dielectric, low temperature matrix isolation techniques in structure determination and intermolecular interactions. Studies of kinetics and reaction mechanisms. Interdisciplinary studies of the properties of hydrogen bonded systems, theoretical and experimental structure determination, with application to biological active substances; molecular mechanics and dynamics; picosecond relaxation phenomena in liquids; optimization methods in spectroscopy, application of chemometric methods for elucidation of structure of biomolecules in solution and for quantitative analysis of drugs .We also have experience in preparing and investigating lanthanide complexes, including mixed lanthanide chelates and metal doped ceramics. Possible applications of the compounds and materials obtained concern, in particular: complexes of lanthanides: nanometer-range media based on metal doped ceramics for powder lasers, mixed lanthanide chelate complexes important in technology of organic layered electroluminescent diodes, metalloorganic compounds which are selective fluoroi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Discovery of New Molecular Semiconductors', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

This project has two main deliverables in the area of organic electronics:(i)A database of molecular semiconductors with predicted high charge mobility. This database contains molecular materials that are characterized structurally but the vast majority of its entries are not tested or intellectually protected as molecular semiconductors. The quality of our predictions was verified in a recent paper published in Nature Materials (doi:10.1038/NMAT4970) and such database is therefore of great commercial value.(ii)A software to predict the charge mobility of newly synthesized molecular materials. Such product will help all developers of new materials to identify their best lead compounds and explore rapidly many variants. Saving time (only the most promising candidates are characterized in full) and reducing the risk of competitors taking advantage of a discovery by minor modification of a good material.The exploitation plan includes intellectual protection (patent) of the best molecules in (i) and copyright of the software (in (ii)), followed by commercialization of both.