RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Sixth Framework proposal on 'New analytical platform for allergen detection'.

assistant: **Concept**

This project is aimed at a better understanding, diagnosis and treatment orientation of allergy, a disease undergoing explosive and worrisome progress. The team will design a new, miniature and automated multicriteria platform for separating allergens from food and/or environmental samples, and for detecting their allergenic activities on patient antibodies immobilised on anti-IgE and anti IgG4 strips. The project proposes a dramatic renewal of protein separation conventional schemes, by combining isoelectr ic focusing with a novel second dimension electrophoresis preserving the native, active structure of the proteins. This paradigmatic change will be associated with the power of newly developed microfluidic (lab-on-chip) systems, and with a new sensitive el ectrochemical method for the measurement of label free affinity sensograms, to allow automated and quantitative multicriteria screening. In contrast with current screening methods for allergy, which search for the response of a patient's serum to a limite d predefined set of known allergens, the approach developed in this project aims at screening the COMPLETE SET of potential allergens contained in a whole food extract (or more generally in any sample relevant to the patient's environment) against the pati ent's IgE and IgG4, WITHOUT ANY A PRIORI LIMITATION, and to identify the nature of the captured immunogens. Thus, besides strong innovation in the methodology of protein separation, the project proposes a radical enhancement in the power of allergen screen ing, with considerable potential for research, diagnosis and treatment follow-up of allergy.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Integrating foraging attributes of domestic livestock breeds into sustainable systems for grassland biodiversity and wider countryside benefits', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

The objective is to identify sustainable grazing management practices for maintaining and enhancing bio diverse grasslands. The effects of management system (targeted at production or at biodiversity) and animal breed (commercial or rustic) on botanical, structural and invertebrate biodiversity will be quantified and the socio-economic costs and benefits evaluated. Integrated investigations in countries will comprise the following tasks:1. Compilation of a web resident European database of research relevant to the management of bio diverse grasslands.2Comparison of animal foraging behaviour;3. Comparison of agronomic output;4.comparison of botanical and structural biodiversity;5 comparison of invertebrate biodiversity;6 socio-economic evaluations. The results will allow improved recommendations for the integrated management of bio diverse grasslands.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Decision making and augmented reality support for automatic welding installations', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Robot welding is critical to welding automation in many industries and it is estimated that as much as 25% of all industrial robots are being used for welding tasks. The biggest challenge for small companies is to have flexible automation that can be set up quickly and can be switched over to another product line. The current proposal addresses the need to increase the competitiveness of welding SMEs by developing a low cost computer vision based welding robot with automatic track calculation and quality control system that can reduce manufacturing time and costs, increase production flexibility, improve product quality and production efficiency. Currently available welding technologies such as manual welding and welding robots have several drawbacks. Manual welding is time consuming, while existing welding robots are not efficient enough for manufacturing small batch sized products but they also often face discrepancies when reprogramming is necessary. This reprogramming is also extremely time-consuming. In contrary, MARWIN will offer a flexible, programmable system to manufacturers and with this solution they will be able to optimize the welding process in a timely and cost effective manner. Aware of the business opportunity and growing market in the welded parts industry, SMEs in the current proposal, with the help of RTD performers, intend to capitalise on this need by developing a product that will overcome the limitations of available systems for end-users, thereby fulfilling a real market need. It will provide a competitive edge for consortium SMEs and within the EU and worldwide in a field where the production of differentiated, high quality welded parts is mainly dominated by large enterprises. By using MARWIN system companies will not only widen the range of p
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Sixth Framework proposal on 'Heat-generated food toxicants, identification, characterisation and risk minimisation'.

assistant: **Innovation**

Modern science has showed that heating of meat and other protein rich foods can generate various kinds of potentially hazardous compounds, some of which are genotoxic and carcinogenic. The focus of the HEATOX project, which is an international collaboration, is health risks recently discovered associated with hazardous compounds in heat treated carbohydrate-rich foods where substantial amounts of acrylamide and similar compounds can be formed. HEATOX will explore their mechanisms of formation, impact of raw material composition, inhibiting factors, cooking and processing methods in industry and households with the to control and minimise the formation of hazardous compounds. Acrylamide is given particular emphasis, however, it is likely that also other compounds such as b unsaturated carbonyl compounds and furans, representing potential health hazards, are formed during heating. It is important that efforts in reducing acrylamide exposure at the same time don not increase the formation of other hazardous compounds. To reduce the exposure, validated methods for food analysis and exposure biomarkers will be developed. Different hazards will be explored and characterised in various toxicological models, e.g. genotoxicity, carcinogenicity, neuro-developmental and reproductive toxicity. Molecular characterisation by toxicogenomics - will be performed. Both experimental animal- and cell systems and also humans will be studied. Particularly the relevance of low dose exposure, bioavailability and extrapolation from experimental systems to humans will be addressed using biomarkers of exposure and effect such as haemoglobin adducts, assessment of DNA binding using accelerator mass spectrometry and a hypersensitive micronucleus assay measuring genotoxicity. The exposure assessment
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'SESAR2020 PJ07-W2 OAUO Optimised Airspace Users Operations' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

The PJ07-W2 Optimised Airspace Users Operations (OAUO) aims at defining and validating improved Airspace Users processes and tools related to their interaction with the ATM Network Operations in SESAR 2020. The current ATM environment based on static flight plans is evolving through SESAR towards Trajectory Based Operations (TBO) in order to improve Airports and ATM Network performance.PJ07-W2 shall develop and validate the following SESAR Solutions:•Solution PJ.07-W2-38 Enhanced integration of AU trajectory definition and network management processes•Solution PJ.07-W2-39 Collaborative framework managing delay constraints on arrivals•Solution PJ.07-W2-40 Mission trajectories management with integrated Dynamic Mobile Areas (DMA) Type 1 and Type 2•Solution PJ.07-W2-38.1 Agreed trajectory revisions in executionPJ07-W2 addresses the following objectives:•develop requirements and validate procedures and workflows for Flight/Wing Operations Centre to interact with ATM stakeholders and especially with the Network Management Function (NMF), with regard to trajectory definition, and to ensure continuity in the Collaborative Decision Making (CDM) process throughout the trajectory life-cycle•smoothly integrate AU Priorities and Preferences in collaborative processes at Airports and in Network Demand Capacity Balancing (DCB) processes, allowing those processes to perform multi-criteria optimization tasks involving many stakeholders•develop high level of automation to reduce the need for Airspace Users and flow managers to intervene through intensive coordination, which is critical for integrated processes to work on an operational scale•improve the interoperability between AUs and the NMF Operations•allow AU Flight Operations to provide the ATM NMF with the most accurate input on t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'A large scale in situ demonstration test for repository sealing in an argillaceous host rock - phase II' (1998-2002) under Fifth Framework.

assistant: **Objectives**

An essential item for the long-term safety of high-level waste underground repositories is the backfilling and sealing of access shafts and connection galleries. The main objective of RESEAL II is to demonstrate on a representative scale that the sealing of a shaft i.e. the experimental" shaft of the HADES underground laboratory, with a low permeability powder/pellets mixture of bentonite avoids preferential migration of water, gas or radionuclides either through the seal of through the excavation disturbed zone around it. The mechanical stability of the seal under accidental overpressure conditions will be also tested. A tracer diffusion in the host clay formation around the seal will allow to study, by modelling, the migration parameters of the excavation disturb ed zone. Hydro-mechanical models will be applied for the interpretation of the test results and consequently to demonstrate our understanding of the seal behaviour."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Towards Novel Inert (Photo-)toxic Ru(II) Polypyridyl Complexes' under Horizon 2020.

assistant: **Concept**

In this grant application, I propose to investigate in-depth the potential of novel inert Ru(II) polypyridyl complexes as novel anticancer drug candidates. Such compounds were investigated by Dwyer and Shulman in 1950s and 1960s both in vitro and in vivo with relatively promising results. This impressive seminal work was unfortunately not followed-up. This lack of additional studies was recently attributed, at least in part, to the observed neurotoxicity of the complexes. Nonetheless, over the last years, there has been a revival of important in vitro studies of such inert Ru(II) polypyridyl complexes for anticancer purposes. However, without further in vivo studies, it is reasonable to think that similar neurotoxicity to that observed by Dwyer and Shulman could be encountered. In order to tackle these (potential) drawbacks, I propose to use a prodrug approach.Furthermore, I also intend to investigate the potential of inert Ru(II) polypyridyl complexes as photosensitizers (PSs) in photodynamic therapy (PDT). In the search for an alternative approach to chemotherapy, PDT has proven to be a promising, effective and non-invasive treatment modality. Importantly, in order to increase even further the potential of the PSs presented in this project, I propose to also excite them via simultaneous two-photon absorption (TPA) in the so-called two-photon excitation PDT (2 PE-PDT). Importantly, the newly Ru(II)-based PSs will be coupled to cancer cell-specific peptides or antibodies. This double selectivity (targeting vector and photo-activation) should limit the frequently encountered side-effects of (metal-based) anticancer drugs. Another important aim of this second part of this project will be the use of the Ru(II)-based PSs to kill bacteria. Interestingly, PDT has been recentl
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Reinforcement of FEED-TO-FOOD Research Center at Institute for Food Technology of the Univetsity of Novi Sad' (FEED-TO-FOOD), addressing dissemination and exploitation.

assistant: **Impact**

Center for FEED AND ANIMAL PRODUCTS (FAP), as organizational unit within the Institute for Food Technology at the University of Novi Sad (UNS), is the only scientific-research unit specialized for a wide range of issues related to the feed technology in our Country and in the region. Due to Serbia's poor economic situation in general, and the previous isolation of the country, there has been no recent investments at the UNS to keep laboratories and pilot plants up-to date, and our researchers had virtually no chance of participating in research and development work going on within EU RTD institutions. Now is the time to prepare a long term sustainable development strategy for Serbia which will enable dynamic economic growth from which the entire population can benefit. FAP is equipped with the laboratory equipments and scientific potentials and willing to take leading position in the region in research area in the production chain from feed to food. Today, the importance of  feed within a food chain is widely recognized and FAP, as the leader in feed technology, want to be a “scientific link” in the production chain from feed to food and want to improve and upgrade their own research potentials  and assist in successful integration of our country, other WBC and the whole region into Europe. Under this proposal, FAP, an already very promising research institution at the UNS focused on  production chain from feed to food, will be developed through the upgrade and renewal of pilot plant equipment, and through the training of staff, in particular young researchers, by academic exchange visits and workshops etc. Proposed project under the title „Reinforcement  of Feed to Food Research Center  at Institute for Food Technology of the University of Novi Sad“ (FEED-TO-FOOD) migh
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Foresight of Evolving Security Threats Posed by Emerging Technologies'.

assistant: **Innovation**

The FESTOS goal is to identify and assess evolving security threats posed by abuse or inadequate use of emerging technologies and new S&T knowledge, and to propose means to reduce their likelihood. Almost all such knowledge can be abused or cause damage through inadequate use. In a free society this should not hinder free generation and exchange of knowledge. As the pace of science-based development accelerates, there is a pressing need for continual scanning of the unfolding technology landscape for potential security threats. Looking ahead to 2030, the foresight study will identify and assess security threats that could stem from future technologies. Robotics, Cognition, New Materials, Nano and Biotechnologies are some of the fields to be scanned. FESTOS will stimulate an ""out of the box"" anticipatory thinking and construct threat scenarios by analysing the impact of the identified threats on the background of envisioned “security climates” (societal context of security issues). The threat scenarios will be evaluated in terms of their levels of impact and uncertainty. In conjunction with each scenarios critical early-warning indicators will be identified, namely signals that hint at a growing likelihood of specific scenarios and thus provide basis for possible prevention means. Societal issues will be discussed, as well as the controversial issue of controlled dissemination of scientific knowledge in the context of necessary trade-offs between security and the freedom of research and knowledge. Finally policy recommendations will be derived, aiming at novel means of preparedness. Adequate mix of Foresight methods will be employed, e.g. horizon scanning, weak signals analysis, expert surveys, brainstormings, “futures wheel”, interactive scenario building, STEEPV anal
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Feasibility study of a NOvel METAbolic liquid biopsy for cancer therapy monitoring' in the context of a Horizon 2020 call.

assistant: **Objectives**

Circulating Tumour Cells (CTCs) are strong indicators of the aggressiveness of metastatic cancer and there is strong evidence that CTCs are a reliable prognostic factor in patients with early-stage and metastatic breast cancer. Despite significant efforts, the detection and identification of CTCs in peripheral blood has proven difficult. The key technical challenge is posed by the rarity of tumour cells in blood, with estimates of just one CTC per ~1-10 million white blood cells per millilitre of blood. Up until now, there has been only one FDA-approved CTC enumeration system, CellSearch®, yet this state-of-the-art method suffers from severe limitations. There is an urgent need for new, alternative methods of CTCs enumeration and further characterization to fully realize the potential clinical benefits of CTC analysis. Lowering cost and speed of analysis coupled with ability to isolate CTC for further analysis would have a tremendous effect on diagnostics and treatment of cancer patients. It would provide novel means for early screening of individuals in a certain risk groups, elucidating most promising therapy options and following a chosen treatment and providing a cost-effective way to monitor patients in risk of relapse. Cytofind Diagnostics has developed a radically new method to count and isolate CTCs based on single cell determination of the anomalous metabolic properties of tumour cells (the so-called Warburg effect). Here, we wish to carefully analyze the potential impact of our technology on different parts of the oncology care cycle and establish which market is most suitable for the first introduction of our disruptive technology.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Collaborative AI Counters Hate' to be submitted under Horizon 2020.

assistant: **Abstract**

Online hate speech and disinformation have emerged as a major problem for democratic societies worldwide. Governments, companies and civil society groups have responded to this phenomenon by increasingly turning to Artificial Intelligence (AI) as a tool that can detect, decelerate and remove online extreme speech. However, such efforts confront many challenges. One of the key challenges is the quality, scope, and inclusivity of training data sets. The second challenge is the lack of procedural guidelines and frameworks that can bring cultural contextualization to these systems. Lack of cultural contextualization has resulted in false positives, over-application and systemic bias. The ongoing ERC project has identified the need for a global comparative framework in AI-assisted solutions in order to address cultural variation, since there is no catch-all algorithm that can work for different contexts. Following this, the proposed project will address major challenges facing AI assisted extreme speech moderation by developing an innovative solution of collaborative bottom-up coding. The model, “AI4Dignity”, moves beyond keyword-based detection systems by pioneering a community-based classification approach. It identifies fact-checkers as critical human interlocutors who can bring cultural contextualization to AI-assisted speech moderation in a meaningful and feasible manner. AI4Dignity will be a significant step towards setting procedural benchmarks to operationalize “the human in the loop” principle and bring inclusive training datasets for AI systems tackling urgent issues of digital hate and disinformation.


**Keywords:** Online Hate Speech, Online Extreme Speech, Artificial Intelligence, Collaborative AI, Hate Speech Moderation, Fact-checking, Disinformation, Internet