RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Prion diseases: Mechanisms of transmission and identification of ta rgets for potential therapeutics' (1994-1998).

assistant: **Innovation**

Considerable advances have made recently in understanding the molecular biology of prion propagation, although many issues remain unresolved. New variant CJD appears to represent transmission of BSE to humans, and it remains to be seen if many more cases will arise. Because of the long incubation period of these diseases the peak of any such epidemic may be as long as 10-15 years ahead. Therapeutic targets are becoming apparent and the development of rational therapeutics appears increasingly realistic. This proposal aims to bring together a number of groups with different but complementary expertise in this area to explore a number of key areas which will underpin the development and assessment of therapeutics. We will attempt to modify PrPC expression and availability, study the effects of PrP polymorphism on PrPSc formation and develop peptides which bind avidly to PrPC and PrPSc, and which may affect PrPSc formation. Cell culture and transgenic models have already been developed and will be further characterised and the range of strain diversity in human prion diseases will be fully determined. As any useful therapy will act at or before onset of the earliest neuropathological changes, these early events in the brain will be characterised and cell populations at particular risk identified. It is anticipated that such studies, in addition to advancing our understanding of prion biology and assessing therapeutic strategies, will help understand fundamental mechanisms of neurodegeneration that may be relevant to other, commoner neurodegenerative diseases.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Decubitus Ulcers Diseases Diagnoses by means of Smart ICT Anti-Decubitus System based on known Ulcers Activity Biomarkers'.

assistant: **Innovation**

The anti-decubitus system JUMPAIR will benefit a large number of patients who are suffering of decubitus ulcers (DeU) orthey are running the risk to suffer it by remotely monitor ulcers biomarkers to improve early diagnoses through DeUprevention, and then through an advanced DeU treatment providing alerts at critical situations by the adoption of smartrelevant ICT solutions for the health, well-being and well-ageing of patients. Additionally, JUMPAIR will also offer arehabilitation programme for patients who suffered of DeU during the bedding in their house or in a hospital. The finalproduct will contribute to prevent DeU and to improve healthcare expenditure containment avoiding unnecessaryhospitalizations and therapeutic treatments. We believe that there is an unmet need in that field to deliver new and moreefficient care to European citizens, and the final systems allows a preventive and therapeutic care of DeU having a greatimpact for physicians and patients who deal with this critical DeU disease.


**Keywords:** ICT monitoring software,  Smart Anti-Decubitus System,  Prevention,  Treatment,  Rehabilitation,  Ulcers Biomarkers,  Decubitus Ulcers Prevention and Diagnoses,  Health, Well-Being and Ageing, Well
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Micro AIS Shore Station - MASS' (MASS) targeting Horizon 2020.

assistant: **Abstract**

Automatic Identification System (AIS) is a VHF based system which is designated to enhance the safety of life and goods at sea by also assuring navigational and environmental improvements. The coverage of national AIS networks are limited because of many reasons (geography, weather conditions, insufficient number of stations etc.) and due to these limitations relevant authorities have difficulties to track and manage the marine traffic properly; causing safety and security weaknesses at sea which also means increased threats of accidents, illegal fishing, immigration & smuggling and water pollution.MASS is a cost-effective, compact-solar powered Micro AIS Shore Station; which is easy to set-up & maintain with lower power consumption rates thanks to its innovative AIS engine. MASS increases safety and security of coasts by enabling advanced monitoring of sea shores, inland waters & lakes and thus eliminating blind spots which are mainly out of the coverage of conventional AIS networks. In order to address this challenge, i-Marine offers a compact-solar powered Micro AIS Shore Station (MASS) which allows better monitoring of sea shores, inland waters and lakes which are mainly out of AIS coverage. MASS is nearly 4 times cost effective over conventional AIS base stations; operates at lower power consumption rates and can operate without a fixed power supply.The objective of this proposal is to prepare a proper feasibility study, which will pave the way to successful introduction and diffusion of MASS into global market and maximize its impact in order to better contribute to European transport and mobility goals defined in 2011 Transport White Paper of European Commission.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Fluorescence-based nano-immunoassay IVD platform'.

assistant: **Objectives**

Antibody-detection related to disease or to drug monitoring demands novel IVD tests that provide robust, rapid and early- stage diagnostics for improved and early on-set treatments. However, companies developing novel IVD immunoassays face an important barrier related to reimbursement policy issues when the IVD tests are introduced into national health systems. This barrier discourages many companies from pursuing the development of novel diagnostic tests because the investment necessary to introduce novel IVD tests in the market is hardly matched by the return of the investment. NIMM aims at providing a platform for the development of accurate, sensitive and inexpensive immunoassays for antibody-related conditions using a novel fluorescent nanosensor-based technology. The outcome of the project will pave the way to a commercial product to be sold in the Immunochemistry/Immunoassay segment of the IVD market, currently valued at 15 USD billion. Potential stakeholders in the outcome of NIMM include Public Health authorities and pharmaceutical companies.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Renovation with automation and optimization of processes and products', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

RENOMIZE presents well-selected innovations in the processes and products for the full renovation trajectory from ideation, over delivery, maintenance and end-of life. Building on an impressive experience in the field, the following innovations have been put forward:•Decision support tools for optimisation of building site preparations, integration of balconies and overhangs, and for the integration and selection of HVAC and RES technology;•Optimisation of the process planning using advancements to spatiotemporal planning;•Development of an improved anchoring system and panel-panel connections, optimised for automized non-sequential mounting, de/re-mounting;•Self-positioning system and end-effectors thereon to support autonomous anchor and panel placement;•Phased optimisation of the factory automation for cost reduction and quality improvement.These innovations will lead to cost savings beyond the aimed 25% and considerable time savings. Elaborate testing for disruptive events is previewed in Switzerland and Spain, while 4 complementary demonstrations will be delivered in Estonia, Switzerland, France, and Belgium.Stakeholders are engaged from the onset of the project, and wider uptake is actively integrated in RENOMIZE’s concept through certification, technical assistance and various capacity building activities.


**Keywords:** Renovation, prefabrication, process planning, factory optimisation
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Humour as an epistemic practice of the political present' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

Something weird is happening in politics. Satirical parties, comedic journalism and memeification are gaining more and more traction; the slippages between parody and sincerity, play and earnestness, real and fake, ridicule and seriousness have proliferated at a dizzying rate. Global entanglements, new technologies, and the surge in populist politics are producing a cacophony of intricate cognitive, social, and economic dissonances bordering on the absurd. The underlying hypothesis of NoJoke is that these dissonances, and the comical reactions produce, have become formative phenomena of the political present; they have seeped into the social fabric and into the ways in which people appropriate their lifeworlds and make sense of themselves and others as political actors.The practice of humour, NoJoke argues, can help us to make sense of the political present; it offers a unique methodology of discovery, a specific education by attention with regards to dissonances that elude conventional academic methods. Bringing together insights from the anthropology of politics and the political, from studies on humour, satire and laughter, and from anthropological advances in ontology, epistemology and methodology, NoJoke will conduct research with humour and humourists, and not merely on them, and establish a radically new approach to the study of the political present. Through a long-term comparative study with caricaturists, comedians, writers of satire, satirical politicians and comedic journalists in Berlin, Brussels, Budapest, Caracas, Johannesburg and the Iranian diaspora, it will follow three objectives: (1) to explore the intrusion of humour and humourists into the field of politics; (2) to articulate a theory of humour as an epistemic practice ? a mode of perception, creat
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Sacrificial Thermoplastic Injection Moulding platform for manufacturing small and complex metal and ceramic components'.

assistant: **Innovation**

AddiFab has developed the first sacrificial thermoplastic injection moulding platform to support the manufacturing of small/medium size, complex and traceable metal and ceramic components with high precison – STIM-MC. AddiFab’s innovative solution is the first to  remove the costly and time-consuming gap between prototyping and commercialization ramp-up. This is only possible due to AddiFab’s proprietary resin and process which uses dissolvable resins to create 3D-printed objects that may be used as injection moulds. It runs in a single platform which integrates the automatic production and postprocessing of moulds. With single-use moulds produced automatically, prototypes and components with mould-like quality can be launched for in-market validation and easily modified. Thus, the STIM-MC platform reduces the product development time and cost, while enabling wider benefits for the healthcare, consumer products and automobile industry through new cost-effective materials. Through the successful development and implementation of the STIM-MC project, AddiFab will be in a strong position to exploit the metal and ceramic injection moulding market, forecasted to reach $5.7 billion by 2022. We expected an acumulated revenue of €167 million, 5 years after project completion.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Expression mechanisms of long term potentiation (ltp) - from molecules to memory' (1998-2002).

assistant: **Innovation**

The proposal concentrates on a central biomedical problem: the nature of the nerve cell changes underlying learning and memory. The objectives are to elucidate the molecular changes occurring in the coupling between nerve cells taking part in a learning process and lay the foundation for new ways to diagnose, prevent and possibly treat memory defects. The objectives will be achieved by using state of the art molecular and biological techniques to analyse a cellular model of learning - long term potentiation (LTP) in the belief that this general phenomenon represents a biological universal which is used by higher and lower animals during learning and memory processes. The proponent experts to detect principles for enhancing the efficiency of molecules (AMPA receptors) which are responsible for the impulse traffic between nerve cells engaging in thought processes. Increased insight may lead to improved prevention and treatment of memory difficulties.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Unravelling the mechanisms behind Multi-Year Droughts', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Recent decades have seen a doubling in multi-year droughts around the world. With long-lasting impact on streamflow, groundwater and vegetation, these negatively affect agriculture, drinking water supply, hydropower, shipping and ecosystems as a result. The IPCC states that contrary to normal droughts, multi-year droughts cause abrupt changes that take years or decades to be reversed. Due to climate change, multi-year droughts are projected to become more frequent and longer, and potential recovery times between droughts will decrease.I hypothesise that the rise in multi-year droughts and their impacts is caused by stronger teleconnections between the atmosphere, ocean and land, enhanced by climate change, and that feedbacks between the bio-hydrological cycle exuberate the impacts of multi-year droughts. The MultiDry project will make scientific breakthroughs by tracking the propagation of multi-year droughts from climate forcing, through vegetation and soil moisture to surface water and groundwater impacts, whilst also including the important, intricate affects of human water use. In MultiDry, I will combine observations with a novel modelling framework to unravel the drivers behind multi-year droughts worldwide, and the feedbacks of vegetation and human water use on drought duration, propagation, and recovery. This will yield new process understanding, novel scientific datasets, and a basis for reliable projections of future multi-year drought events.This project will drastically improve our understanding of the drivers and mechanisms of multi-year droughts that I believe to be fundamentally different from those of normal droughts. The MultiDry results will inform policymakers and water managers around the world on future water challenges. MultiDry will also provide t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Development of a test method for banned azo-dyes and production of a certified reference material (AALARM)' to be submitted under Fifth Framework.

assistant: **Abstract**

The objectives of this project are to optimise a test method to allow measurement of banned azo-dyes in leather. A certified reference material (CRM) will be developed to ensure accurate and reliable results. Work carried out will include evaluation of reduction conditions, sample clean up, and chromatography along with minimization of false positive results. Inter-laboratory trials will be carried out along with homogeneity and stability studies on the proposed CRM.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Towards Harmonised European Statistics on International Migration' under Sixth Framework.

assistant: **Concept**

Migration has become a top priority for European Policy while international migration statistics are among the less reliable statistics within the field of socio-economic and demographic data. Concretely THESIMproject aims to develop additional efforts parallel to the forthcoming action plan for statistics on international migration. In order to reach this objective we intend to investigate with all 25 EU MS and AAC in several directions :  1° to compare definitions and concepts related to international migration;  2° to analyse available data in order to see what the data already reveals and where are the main problems in terms of reliability and comparability;  3° to integrate data on asylum with data on flows and stocks in order to get the more reliable information on de facto international migration within each country;  4° to describe and analyse all efforts done on bilateral and international levels in order to improve the situation and to identify impact of low reliability and lack of comparability on policy implementation;  5° to propose practical recommendations on the way to improve the situation after discussion with all potential data providers and data users for migration policy development.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Supramolecular & Covalent Bonds for Engineering Spatiotemporal Complexity in Hydrogel Biomaterials', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Current biomaterials poorly recapitulate the tough, responsive, and spatiotemporal behavior of native extracellular matrices (ECM). This recapitulation of ECM complexity is imperative to create environments that can effectively communicate with living cells. A key missing component in synthetic ECM-mimetics is spatiotemporal control of material dynamics. Supramolecular biomaterials hold significant promise to fill this need, yet their poor mechanical properties often limit application. I hypothesize that strategic combinations of dynamic supramolecular assemblies with reversible/degradable covalent bonds can lead to tough, hierarchical, and spatiotemporally complex hydrogels. After all, nearly all hierarchical materials in nature are composed of optimized combinations of supramolecular and covalent bonds. In SupraValent, I will test my hypothesis with the design and exploration of spatiotemporal changes to hydrogel properties via covalent modification of 1D supramolecular polymers. SupraValent will first create structure/dynamics/property relationships of supramolecular assemblies between solution-phase studies and hydrogel materials. I will leverage this information to create tough supramolecular biomaterials and bioinks, which allow for the introduction of spatiotemporal gradients and cell-mediated changes (via degradation) to the material’s properties. Then, I will introduce innovative cell/material constructs where the cells create covalent bonds on the materials over the lifetime of culture. Here, genetically modified bacteria will introduce the spatiotemporal complexity into the construct, moving towards living material’s modifications. These studies will transform the way we create and control timescales in dynamic biomaterials, and open supramolecular hydrogels