RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'ACADEMIA AND INDUSTRY UNITED INNOVATION AND TREATMENT FOR TUBERCULOSIS'.

assistant: **Concept**

Current anti-tuberculosis (TB) drug regimens face serious limitations at times of increasing antimicrobial drug resistance. Fortunately, for the first time for centuries, several novel anti-TB compounds are available for clinical evaluation. As the traditional approach to testing these in multiple combination regimens is too slow and inefficient new approaches of clinical phase 2 study designs are required if we are to meet the targets of the WHO EndTB strategy to save the lives of millions into the near future. Our consortium brings together a unique group of European and international leaders in TB research and leading industry partners. Together we will provide the necessary comprehensive range of expertise to meet the demands of the UNITE4TB scientific research agenda. Specifically, we will develop a new global standard for phase 2 TB clinical trial designs, utilising simulation tools to identify optimal doses in phase 2A trials and apply a multi-arm multi-stage adaptive randomised controlled 2B/C trial design capable of rapid and simultaneous evaluation of the best candidate regimens. Our innovative phase 2 trials will be performed to the highest regulatory standards, incorporating state-of-the-art microbiology, biomarker investigation and clinical pharmacology. We will take advantage of existing global TB clinical trial networks with the capacity to enrol patients at an unprecedented pace and number across four continents. Artificial intelligence/machine learning technologies will be applied to validate state-of-the art molecular and imaging tools as treatment decision biomarkers with the aim of establishing new, real-time outcome measures. Our consortium will evaluate 3-5 new chemical entities (NCEs) at phase 2A and up to 17 novel combination regimens in phase 2B
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Sustainable Integrated micro-Algae Culturing System (Sustain-ALGae)' under Horizon 2020.

assistant: **Concept**

Truly high profits wait for those that take algae culture to the next level. This has been known to the food and animal-feed industry for some time, as bio-mass produced by microalgae is both immensely valued and highly priced. Bioactive compound of the micro-algae in question is 5 % of the algae mass and the price is 10.000€/kg. The remaining 95% are high quality proteins and lipids used for fish feed and later for food. These highly valued and priced algae-based compounds are however a scarcity in today’s markets due to technical obstacles in algae farming as today’s reactors only enables harvest in areas where outdoor culture of microalgae is feasible.The innovation in question offers a solution to this obstacle namely a tank based photo-bio reactor which has the potential to address the economical and social challenge of feeding the ever growing world population. The solution is highly productivity LED reactors for mass culture of microalgae. Presently being scaled up from 1000L to 5000L.  The reactor enhances harvest/m2 by 400%, harvest by Kw hr. by 100%, lowers production cost by 30% and lowers capital cost by 20% and decreases losses in production from 30-50% down to 5%.  A pilot version of innovation has already yielded a “cash cow” for the applicant, based on the highly price valued 5% concentration of astaxanthin - the compound that makes salmon red. The compound will be sold as capsules in late 2017 to an Italian pharmaceutical corporation dedicated to creating novel medicines for the unmet needs of patients with rare diseases. The market’s demand proves what enormous potential that the photo-bio reactor has for food and animal-feed farming in Europe as well as for the pharmaceutical industry.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'E-Government for low socio-economic status groups' in the context of a Sixth Framework call.

assistant: **Objectives**

Information and communications technology provides governments with new and powerful tools, which enable better and faster communications with the citizens. Recently, many governments are undertaking large and complex endeavours of developing e-Government services. However, the use of e-Government by the citizens is still voluntary. Thus, readiness of citizens to participate in e-Government becomes a crucial factor in the process. Usage of services depends on various factors such as ease of use, proficiency, accessibility and civic engagement. In most countries there are several disadvantaged groups that are less likely to use services.These groups include elderly people, disabled people, immigrants and low socioeconomic groups (LSG). Since the computer usage by LSG is very low, web-based e-Government services are not available to a relatively large segment of European citizens. The pace at which countries deploy e-Government services, including measures taken to include LSG, vary considerably across Europe. Excluding such populations from e-Government is a major cause of the digital divide within European countries. The main objective of ELOST is to increase readiness to e-Government and civic engagement among LSG. ELOST aims to increase the number of people from this class that will use e-Government services as active citizens. ELOST will perform a multinational study on the policies and plans to introduce e-Government to LSG. Special attention will be given to age and gender aspects.The objectives are to study the status of e-Government services and tools for LSG in European countries. ELOST will evaluate the attitudes, needs and readiness of LSG by means of questionnaires, interviews and focus groups. A foresight study will analyze the impact of emerging technologie
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Resource failure and restoration management in atm-based ibcn' in the context of a Fourth Framework call.

assistant: **Objectives**

The scope of the REFORM project is to specify, design and develop a system providing the necessary means and functions for ensuring network performance and availability within acceptable levels under normal and fault situations. Specifically, the objectives of the REFORM project are:1. To study, specify and developin the control planeOAM mechanisms for fault detection, focusing on faults caused in or escalated in the ATM network layer;fast and reliable ATM network layer self-healing mechanisms and related OAM protocols;efficient routing and spare resource control algorithms;in the management planeadaptive load balancing algorithms with inherent self-healing capabilities and suitable fail-safe protocols for routing information exchange;intelligent dynamic distributed and centralised routing algorithms and service migration algorithms, coping with fault conditions;cost-effective spare resource allocation and management schemes;with the overall goal to ensure:cost-effective network performance and availability in normal conditions, andcost-effective, reliable and robust network recovery in fault conditions, ensuring the performance of existing connections and in network availability for new connections.2. To design and implement REFORM system prototypes byadopting a CORBA-based TINA framework for realising the management systemby interworking with appropriate TMN componentsby adopting appropriate means for implementing the REFORM control system components so that the time critical requirements are met.3. To assess the validity and effectiveness of the developed OAM protocols, self-healing mechanisms, routing load balancing and resource management algorithms as well as the design of the REFORM system as a whole, in the context of field trials on NH platformsThe project, thr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Promoting Opportunities for Wide-scale Energy Renewal: Unlocking Potential' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

The market uptake of RES depends on a complex combination of political, geographical, economic, social and cultural factors that are specifically intertwined in each locality. In addition, the acceptance and willingness of directly affected stakeholders to support the deployment of RES depends on the perceived fairness about how the decisions are made (procedural justice) and how the benefits are shared (distributive justice). POWERUP adopts a holistic approach towards the market uptake of RES for electricity and provides a set of open source tools and methodologies addressing all these factors, tailoring the RES projects to the local conditions and increaseing their acceptability and market uptake. The tools include a GIS-based decision support tool for initial feasibility assessment, a business model toolkit for reconciling stakeholder requirements and producing equitable business models, and a co-creation toolkit for engaging the stakeholders in co-design of a RES project that is reproducible and tailored to the local needs and conditions.The tools are supported by a social acceptability strategy for RES that provides guidance for considering all social aspects in the decision-making and design process.The POWERUP tools and methodologies will be extensively validated in 4 European regions and replicated in 10 follower regions, covering a variety of conditions all over Europe. The project aims to involve >700 public and private stakeholders and organise 46 workshops, incresing the perception of fairness of the RES business models by 80% and the community acceptance by at least 50%. The project consortium is a team from 5 EU countries that comprises regional energy agencies, public authorities, universities, and research centres and includes leading experts in Social S
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'SEnsorial awareNess System fOR obstacle detectIon And collisioN avoidanCE' (SENSORIANCE), addressing dissemination and exploitation.

assistant: **Impact**

The goal of this project is to develop a cost-effective system to provide the aircraft with high-definition vision capabilities in the IR  and visual spectra.   This vision system combines information from various sources, including a compact camera –consisting of a cost effective, versatile, high-performance and highly-reliable optical system— and external sensors, distributed in the form of LRU modules. This information is then processed by a computer vision and image processing module to infer useful knowledge and event-reaction capabilities, aiding pilots during all phases of flight (taxi, takeoff, cruise, and landing). The visual information perceived by the pilot’s natural vision is enhanced (or even replacing, when needed) via an advanced flight vision and awareness system that provides obstacle detection and avoidance, as well as increased visibility for all weather conditions, increasing safety on flight operations.The developed system will be ITAR-free, to avoid delays related to export controls by the US, increasing its versatility and making it more appealing for prospective customers. This, along with the system’s lower cost due to the use of more affordable components, would substantially increase its chances to compete with other similar solutions worldwide.SENSORIANCE system will provide a complete enhance and synthesized images suite and it will allow:• To enhance the field of view. • To reduce the risk of occurrence of an impact.• To Enable air transport system optimization • To ensure compliance with safety standards and regulations. • To use ROHs components• Requiring low investment in devices (COTs) The SENSORIANCE applications span from industrial and vision related applications to aircraft Electro-Optical applications.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'A Political History of the Future : Knowledge Production and Future Governance 1945-2010' (FUTUREPOL).

assistant: **Concept**

FUTUREPOL seeks to open up a new field of historical and political enquiry around the history of future governance. As an object of governance, the future is notoriously rebellious: difficult to define, defying notions of objectivity and truth. Nevertheless, a crucial feature of modern societies is their belief in the knowability and governability of the future, the belief that through the means of scientific rationality and political power, the future can be controlled. FUTUREPOL aims to study shifting ideas of the knowability and governability of the future, in order to illuminate the process in which the future is transformed from its nebulous and uncertain state into an object of governance. Moreover, it intends an historical analysis of how this process varies over time in the post war period. The project thus asks two central research questions: How does the future become an object of governance? And how is this process different today, than earlier in the post war period? FUTUREPOL will address four problems: First, it will study the origins of futurology and its birth in transnational networks of futurists in the immediate post war period. Second, it intends to study the way that futurists’ ideas were translated into policy and gave rise to public institutions devoted to the future in many countries in Europe and beyond. Third, it will situate these problems in a global field where concerns with national futures are confronted to concerns with the survival of the world system as a whole, and fourth, it aims to study the evolution of the means of future governance over time, and proposes that such an historical analysis of future governance can permit us to historicize central forms of modern governance such as the governance of risk, foresight or scenarios, and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'B-cell development and gene regulation in three dimensions' (2007-2013).

assistant: **Concept**

A major challenge of modern cell biology is to understand how elaborate transcriptional programs drive developmental processes and maintain cellular identity. In mammals temporal and cell type specific gene regulation depend on regulatory elements in the genome. Genome-wide mapping studies have lead to the identification of myriads of regulatory elements. Strikingly these elements not only exist in abundance compared to genes in the genome, but they are also preferentially located distal to transcriptional start sites in intronic or intergenic regions. Therefore, in contrast to promoters, many regulatory elements can be separated by large genomic distances from their target genes and thus their function can not readily be predicted. A growing body of evidence suggests that regulatory elements exert their function through direct physical interactions mediated by chromatin looping. Thus, in order to accurately describe transcriptional networks and gene-regulation in the frame of B-cell development or indeed in any other cell system, these interactions need to be experimentally determined.This proposal aims to map interactions between regulatory elements on a genome-wide scale in early B-cell development. Data will be utilized to generating the first transcriptional networks based on interactions between regulatory elements. Further, transcriptional networks will be integrated with transcriptional profiles to validate accuracy of models. Taken together the proposed project should greatly increase our understanding of how transcriptional networks drive developmental progression within the frame of B-cell differentiation.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'ERA-NET: Sustained collaboration of national and regional programmes in cancer research'.

assistant: **Objectives**

Cancer is a worldwide health burden and a major public health challenge. Despite significant advances in the understanding, prevention, diagnostics and treatment, cancer remains a public health problem in Europe and the world. In such a setting, translational cancer research plays a key role in successfully addressing the growing burden of cancer.The great potential of translational cancer research in Europe will only be achieved when the main barriers are systematically addressed through concerted actions between public and private organisations that provide funds for research, researchers, healthcare providers and all those engaged in the cancer research spectrum. Moreover, adequate and systematic financial support backed by a strong political commitment is absolutely essential to help reduce the burden of cancer that European citizens are currently facing.In this context, the TRANSCAN-3 network, with a strong background in funding cancer research, embodies an excellent model of cross-national cooperation by bringing together 31 funding organisations, from 20 countries, with the common goal of supporting high-impact translational cancer research through cross-national joint calls for proposals, and by an efficient investment of dedicated national/regional public funding, leveraged with foundation/charity-based resources and EU financial support.Building up on the well-established cooperation and accomplishments, through the harmonisation of national/regional funding mechanisms and programmes, plus continued and sustained series of efforts for the access to and sharing of data on cancer research, this TRANSCAN-3 project also aims at becoming a catalysts for a sustainable model of funding of high-impact cancer research in Europe and beyond, with an approach to effective
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'ANISOTROPIC RESPONSE OF UNSATURATED SOILS: A MICROSTRUCTURAL APPROACH' (AREUS) under Seventh Framework.

assistant: **Objectives**

The expression “unsaturated soil” is used in geotechnical engineering to identify a class of soils whose pores are partially filled with water and partially filled with air. Unsaturated soils occur naturally above the water table as a superficial ground layer, whose thickness depends on the balance of precipitation and evapo-transpiration and, hence, on the prevailing local climatic conditions. Unsaturated soils also occur in manmade structures that are built by compacted earth such as embankments, gravity dams, barriers for underground nuclear waste repositories and flood defences. The engineering properties of unsaturated soils are therefore crucial to many civil engineering applications as well as to geohazards engineering (e.g. slope instabilities and landslides). The response of unsaturated soils to loading and environmental actions is crucially dependent on the mechanical anisotropy of this material. Anisotropy in unsaturated soils may be caused by two concurring factors, i.e. the nature of the soil fabric and the deviatoric component of the inter-granular stress generated by capillary pore water. This project aims at investigating anisotropy in unsaturated soils based on the appreciation of the microscopic interactions between solid grains, pore water and pore air. The research is divided in four main tasks: a) performance of laboratory tests on unsaturated soil samples compacted under different conditions to achieve different degree of initial cross-anisotropy, b) interpretation of test results in terms of theoretical models based on the mechanics of granular materials and continuum mechanics, c) microscopy analysis of soil samples subjected to cycles of wetting and drying and 4) study of boundary value problems where the anisotropy of unsaturated soils is parti