RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Structurally informed Design of Masonry Assemblages Composed of Interlocking Blocks' (SiDMACIB), addressing dissemination and exploitation.

assistant: **Impact**

Masonry benefits contemporary architecture regarding sustainability and application to free-form construction. A masonry structure can be considered as an assemblage of conventional or interlocking rigid blocks with frictional joints. Although interlocking blocks’ resistance to sliding is higher and their construction is easier when compared to conventional blocks, there is no digital framework to design structurally-sound assemblages composed of interlocking blocks with diverse typologies. Therefore, I intend to develop a digital framework that supports designers in the design of structurally feasible and assemblable masonry assemblages of interlocking blocks. The framework will accomplish the following:-it allows designers to model an assemblage and to analyze its structural feasibility;-for the structurally infeasible model, it will automatically modify the geometry of the interlocking blocks’ connectors, making the model structurally feasible; -during the geometric modification, it will avoid geometries which do not construct the assemblable blocks. To evaluate the structural feasibility, a novel experimental method will equate the frictional resistance of the corrugated face of an interlocking block to that of the flat face of an equivalent conventional block. I also propose an extension of the limit analysis method, in which block resistance to sliding is different in different directions, and plan to use equations from the experimental method.The project is an interdisciplinary research in the fields of architectural, computational and structural design and will train skills helping to establish me as a researcher leading studies on structurally informed architectural design as well as to become an entrepreneurial architect who uses masonry in contemporary archit
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Deciphering the life histories of chronic lymphocytic leukemia to improve clinical outcome' to be submitted under Horizon Europe.

assistant: **Abstract**

A holistic view of the history of cancer is not only essential to better understand its pathogenesis, but also has a clear impact by improving future prevention schemes, personalized management strategies, and treatment options. Importantly, the roadmap of a tumor is incomplete without knowing the molecular composition of its normal cellular counterpart (NCC), cell of origin (COO), clonal trajectories, and interactions with the tumor microenvironment influencing disease progression and response to therapy. In chronic lymphocytic leukemia (CLL), the most common adult leukemia in Western countries, and Richter transformation (RT), its aggressive progression, these fundamental aspects remain largely unknown. In this project, named CLL-STORY, I aim to fully reconstruct the life histories of CLL to improve clinical outcome. To that end, using novel methodological breakthroughs and functional readouts, I will (1) generate a detailed multi-omic atlas of normal B cells to properly delineate the NCCs of CLL and their precise nature, allowing me to clarify the role of (epi)genetic drivers in CLL promotion, (2) characterize the COO of CLL and its lifelong clonal trajectories to resolve the disease origin and growth patterns dictating the different clinical courses, with the ultimate aim to control early disease precursors and anticipate disease evolution, and (3) determine the mechanisms of resistance to immune-based therapies, as well as intrinsic and extrinsic features influencing their anti-tumor efficacy, to aid the development of predictive models and improvement of current treatments, which shall improve clinical outcome. In summary, CLL-STORY explores uncharted territories unraveling clonal mosaicism, early cancer development, tumor phylogenies along human lifespan, and mec
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Supporting the transition towards circular economy in European cities and regions: Development of a replicable model for local circular economy projects' (InvestCEC).

assistant: **Concept**

With 75% of the EU’s citizens living in urban areas, the potential of circular economy for European cities is clear. However, one of the main issues hindering a widespread deployment is that compared to industrialized economies, circular economy business cases are often perceived as risky by investors, often because the business models are poorly described or understood. InvestCEC will develop a replicable model for the implementation of circular economy projects in cities and regions across Europe, while taking into account all relevant stakeholders. Specifically, the model will address the city and region’s needs, support entrepreneurs in making their circular economy solution investment ready, and include the investment program set up and management. The model viability will be then demonstrated in the city of Klagenfurt, Austria as a test case. InvestCEC will also develop a platform for the stakeholders involved in a circular economy project to communicate, exchange information, as well as monitor the project and its progress. A tailored replication plan including replication materials and replication activities will be established in order to encourage the replication of the model in other local and regional settings across Europe. Alongside the model’s development and demonstration, the project will carry out prospective activities and implement measures to support the transition towards circular economy, including policy-related work, information exchange events, marketplace of circular economy solutions, and additional resources, tools and guidelines for the use of all stakeholders.


**Keywords:** Waste management, rereplication, circular cities, circular regions, CCRI, imapct investments, circular economy investments, replicated model, circular economy policy
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Integration of advanced experiments, computation and data for Duplex Stainless Steel joining innovation' (2014-2020), addressing dissemination and exploitation.

assistant: **Impact**

The proposed project aims to collaboratively research on welding of duplex stainless steel (DSS) through modern data system/sharing, experiments and predictive physical modelling for developing new materials and processing regimes. The project will establish a systematic data system for the key physical structure/phases relative to the welding and corrosion of DSS. The project will establish the optimum welding regimes for enhanced mechanical and corrosion performance with the aids of hybrid computer aid design and manufacturing (CAD/CAM) and physical based material modelling. The data and advanced approach will be used to develop new disruptive manufacturing technology to control the structure, phase and defects in the welding in particularly the heat affected zones (HAZ), which is the most critical/limiting issue for manufacturing and applications of DSS and other material systems. The work will jointly explore the use of modern data and predictive modelling technology in developing dissimilar/hybrid material systems for more significant weight/cost reduction. The resulted advanced data system, new materials, welding process and hybrid lightweight materials will contribute the research and innovation capacity in Europe and the world on DSS, stainless steels and associated systems with a long term economic and social impact (e.g. health, environments and society). The advanced data system will serve as a pivoting platform for future research and innovation, speeding up material or product development cycle, with fundamental contribution to academic and industrial R&D. It will enhance the R&I capacity of inter/multidisciplinary intersectoral partners, and jointly developing major break-through technologies. The work combined several novel approaches I R&D, will contribu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Social complexity in Resource Management' to be submitted under Seventh Framework.

assistant: **Abstract**

This research projects starts from the observation that in some instances, government intervention is effective in conserving renewable natural resources, such as fish stock, but not in others. We argue that government intervention does not take place in a vacuum, as sets of social norms may exist that govern resource use. In some cases these social norms promote sustainable harvesting strategies, but they may also aggravate overfishing if they are merely aimed at reducing costs of exploitation. Success or failure of government intervention depends crucially on how this intervention interacts with the local set of social norms. We hypothesize that these social norms are shaped by the state and dynamics of the natural resources and hence co-evolve with these resources. The key objective of this project is to analyze how decisions of resource users are influenced by the biological and institutional environment. Specifically, we aim to identify, first, under which conditions social norms of resource exploitation evolve; second, how quickly these social norms adapt and respond to environmental changes; and third, how government intervention interacts with these social norms. The execution of this research project is explicitly interdisciplinary and stimulates close cooperation between economists and biologists. We combine mathematical biology with economic modeling and behavioral experiments, to obtain a unique mix of methods allowing us to address the research topic. Our approach is innovative as we explicitly take into account that the institutional setting is not an exogenous constant, but over time, institutions are determined endogenously through the interplay between economic, social and ecological forces acting on the system. This research combines insights from beha
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Photoinhibition: Nature of the process and Influence on primary productivity Across Scales' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

Photosynthetic microbes contribute over 50% of carbon fixation on Earth. Inhabiting extremely diverse environments, they always have to cope with a friend that is simultaneously their enemy: sunlight. Photon energy is necessary for photosynthesis, but it continuously damages the photosynthetic apparatus, primarily the first enzyme in oxygenic photosynthesis  Photosystem II (PSII)  in the process of photoinhibition. Upon photodamage, PSII becomes irreversibly inactivated, unable to do electron transfer, and requires costly repair involving protein translation. Photoinhibition represents a major limiting factor to terrestrial and aquatic photosynthesis.  Despite decades of research on PSII and photoinhibition, many key aspects of photoinhibition remain unresolved, among them: -the site within the PSII complex where the photoinhibitory damage takes place, as well as its molecular nature -partitioning of the known different types of damage, dependent on the environment and conditions -the role of the mysterious haem b559, conserved in phototrophs close to PSII reaction centre and transferring electrons, long speculated to play a role in photoprotection but with no convincing role assigned to date  In PHOTONICS, I aim to focus on these issues to provide a thorough description of photoinhibition and photoprotection strategies in photosynthetic microbes. I will use a combination of novel in vivo methods, taking advantage of the most recent developments in time-resolved fluorescence- and absorption spectroscopies. These will be combined with genetics and state-of-the-art structural biology. It is the integrative nature of PHOTONICS, bridging different scales of complexity in a hypothesis-driven manner, that will allow to finally resolve the critical missing pieces of PSII funct
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Geometric algorithms for transport network graphs' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

Graphs have been used to analyse transport networks for hundreds of years. However, graphs are general structures and many graph algorithms are very slow. Specialised algorithms are much more efficient but can only be applied to restricted graph classes. Transport network graphs suffer from a lack of efficient specialised algorithms, since most graph classes are too restrictive and do not accurately represent real-world transport networks. Recent developments have led to geometric graph classes that are tailored to real-world transport networks. One of these geometric graph classes, phi-low-density graphs, captures the property that there are more connections between geographically nearby nodes than geographically distant ones. Unfortunately, the fundamental properties of phi-low-density graphs are not well understood, which has prevented the development of a wide range of specialised algorithms. My objective is to fill the acute need for a simple and versatile graph class that accurately represents real-world transport networks. My research will allow experts to finally harness the power of specialised algorithms on a wide range of important transport network problems. I will achieve my objectives through two sub-objectives: (1) To build fundamental structures for phi-low-density graphs, and (2) To design provably efficient specialised algorithms for phi-low-density graphs. I will be support by my host institution (University of Copenhagen), my host group (Basic Algorithms Research Copenhagen), my primary supervisor (Mikkel Abrahamsen), and my secondary supervisor (Rasmus Pagh).


**Keywords:** Geometric algorithms, Graph algorithms
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Critical, Bottom-up and Material Geopolitics of the European Union in the Black Sea' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

The Russia-Ukraine War has elevated the geopolitical significance of the Black Sea. The sea has become a site of military battles, blockaded trade routes, and environmental degradation. The entanglement of this body of water with many contentious developments underscores the need for a deeper and multifaceted understanding of its role in contemporary geopolitics. Yet, the military-strategic analysis, which dominates the academic scholarship on the Black Sea, ignores other important geopolitical dimensions, such as interests and knowledge of the local coastal communities and the materiality of the sea water in shaping geopolitical relations. The project, therefore, aims for a critical, bottom-up and material geopolitical reframing of the Black Sea in which the body of water and its coasts remain both a central object of analysis and a key site of study of geopolitics. Empirically, the research focuses on the Black Seas role in the European Unions (EU) geopoliticization of its European Neighbourhood Policy (ENP) since 2014. It investigates the Black Seas role in the European Unions geopolitical agenda and practice. Methodologically, the research brings different geographical scales and vantage points on the Black Sea geopolitics together, such as the EU institutions in Brussels, coastal communities on the Black Sea, and the sea itself, in order to capture various elements and phases of EUs practice of geopolitics from inception to implementation and finally, effect and impact.


**Keywords:** Black Sea,  EU,  European Neighbourhood Policy,  Critical Geopolitics,  Maritime Geopolitics,  Borders,  Territory,  Assemblage
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Optimization of target-effector interactions of prophylactic anti-Rhesus D antibodies: studies of structure-function relationships of variable and constant domains' (1994-1998), addressing dissemination and exploitation.

assistant: **Impact**

The objective is to design two types of novel bioengineered IgG anti-Rhesus D moleculares: - one for the prevention of immunisation against the Rhesus D; - the other with the capacity to prevent the binding of harmful maternal antibodies to the Rh(D) antigen on fetal red cells. These bioengineered IgG anti-D molecules can be produced at large scale by the biotechnology industry and will provide the EU with - a safe and unlimited supply of anti-D for the prophylaxis of Rh(D) immunisation; - a non-invasive therapy for the treatment of fetal anaemia caused by anti-D.We will achieve our objective by the use of hybridoma technology, recombinant protein engineering, phage display technology, in vitro bioassays, transgenic mice (Rh mouse) and monkeys. The proposed project consists of three main parts, structure-function studies on i) the variable domains and ii) the constant domains of anti-D antibodies and iii) studies using animal models to assess the suitability of bioengineered IgG anti-D molecules for therapeutic use. On the one hand the aim of the structure-function studies is to improve on the capacity of the bioengineered anti-D to clear Rh(D) positive red cells from the maternal circulation. On the other hand we expect to design an IgG anti-D molecule with a novel" constant domain capable of being transported across the placenta but made incapable to recruit the classical Fc receptor (FcR) functions. Such a biologically "inactive" IgG anti-D preparation will compete with the maternal anti-D for binding and can thus prevent fetal anaemia. The principle of displacing harmful antibodies against blood cell antigens could also be applied to other immune-mediated cytopenia's of the blood. It is proposed to investigate the use of mice transgenic for the Rh genes as a test mo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Tensor Processing on FPGAs for Artificial Neural Networks' (TPANN).

assistant: **Concept**

Artificial neural networks have been shown to offer a powerful computing approach to encounter many classification problems as in synthetic vision (e.g. autonomous driving) and artificial intelligence (e.g. AlphaGo). While their implementations are often based on power-hungy CPU- and GPU-installations, first researchers have delivered initial application-specific solutions that demonstrate FPGAs to be a feasible and efficient alternative. This proposal aims at providing a generic reference implementation of ANNs on FPGAs that is tunable towards various application needs by parametrization. Since individual FPGA designs establish enormous costs of entry due to a higher engineering effort on a lower abstration level, an IP core that is available out of the box is a great R&D incentive that enables more researchers and engineers to embrace the emerging efficient heterogeneous computing more quickly and produce innovations and more compact and more efficient products on this basis. Besides this technological advance, this proposal enables a researcher with an enormous experience in mapping computations into FPGA hardware to make a valuable industrial experience in an international context with the major company in this domain. His expertise is ideally complemented with the application experience available at Xilinx who will benefit from opening a new growing market for manufactured FPGA devices. The development of the researcher's skill set is explictly addressed by complementing his academic background with industrial experience and scheduled cooperate trainings. As part of the dissemination activities, his network into the FPGA community is strengthened and approaches towards the ANN community are made.