RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Sixth Framework proposal on 'Role of IL-6 in the increased food intake and adiposity during pregnancy'.

assistant: **Concept**

Pregnancy is a hyper-metabolic state with a great increase in maternal body fat and weight, and it is associated with numerous neuro-endocrine changes. During gestation, there is no increase in energy efficiency, and the energy balance becomes positive at this stage, primarily because of a marked increase in food intake, which is necessary to prevent the depletion of maternal energystores. Interleukin (IL-6) is a multifunctional immune-modulating cytokine that has been suggested to have important functions in glucose and lipid metabolism. IL-6 is secreted from adipose tissue to the circulation, and its expression is positively correlated with BMI and total fat tissue. IL-6 deficient (IL-6-/-) mice develop obesity, which could partly be reversed by IL-6 replacement, suggesting a role for IL-6 in long-term regulation of adipose tissue mass. Furthemore, intracerebroventricular (ICV) injections of a low dose of IL-6 decreased food intake and increased energy expenditure in rats, suggesting a central site of action of IL-6. By using theIL-6 deficient mice as a tool, we will carefully analyse the long-term effects of lack IL-6 on bodyweight, fat mass distribution, food intake and metabolism during pregnancy and lactation.Several hypothalamic neuropeptides have been identified as possible regulators of food intake and metabolism. These neuropeptides have been reported to display either orexigenic (NPY, AgRP,MCH and orexins) or anorexigenic (POMC, CART, and CRH) functions and to be inhibited or stimulated by leptin levels, respectively. Nutritional status can alter the expression of these appetite-regulating peptides, but most studies have investigated acute changes with fasting, and the effects of a long-term state of hyperphagia as gestation remains to be fully defined. Durin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Hydrogen storage research training network' (HYTRAIN), addressing dissemination and exploitation.

assistant: **Impact**

HYTRAIN integrates the leading centres in Europe active in hydrogen storage research within a coherent framework of dedicated networking activities focused on the training of young researchers through a joint innovative research programme. The core researc h objectives of HYTRAIN are to: propose and assess innovative methods of storage from the point of view of full engineering design; allow for a better response time to suggested novel storage materials, enabling quick assessment and development to the prot otype stage; achieve an accelerated transfer of research results to the corresponding engineering applications; and to ensure that basic research is informed by industrial, economic and social imperatives. HYTRAIN's places an emphasis on longer-range solut ions, primarily hydrides and porous stores, with a view to identifying potential lightweight storage solutions and an aim of work towards practical storage tank design and hybrid solutions. Currently, no single hydrogen storage technology satisfies all of the criteria required by manufacturers and end-users. HYTRAIN's scientific and technical activities have been structured to address the improvement and development of current and novel hydrogen storage technologies and it will lead to the generation, expl oitation and dissemination of new knowledge in a number of strategically important research areas, namely: hydrides, porous media, storage tank design and hybrid systems. The HYTRAIN research work plan takes into account the fact that the research methods for both hydrides and porous media use a number of common techniques and equipment, particularly with regard to sample characterisation. The rationale for this is that trainee researchers are likely to obtain a greater benefit at the research training lev el fr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'GRACIOUS:  Grouping, Read-Across, CharacterIsation and classificatiOn framework for regUlatory risk assessment of manufactured nanomaterials and Safer design of nano-enabled products' (GRACIOUS) under Horizon 2020.

assistant: **Objectives**

Manufacturing and functionalising materials at the nanoscale leads to a whole array of nanomaterials (NMs) varying in e.g. size, morphology and surface characteristics. Apart from expected benefits, distinctive properties of NMs may also affect (environmental) health risks. Safety assessment requires sufficient information for each NM, but testing every unique NM for their potential adverse effects is virtually impossible. More efficient ways to obtain safety information are needed, which could be achieved by applying grouping and read-across approaches to NMs. On a conceptual level, regulatory accepted approaches for grouping and read-across for NMs already exist, but actual application remains difficult as the required knowledge is not systematically brought together,   lacks data curation or is still missing. GRACIOUS will address this urgent need by developing a framework for grouping and read-across based on physicochemical, release, exposure, environmental fate, toxicokinetic and toxicological information. This framework will be delivered as a practical e-tool, fit-for-purpose for various key (regulatory and industrial) stakeholders, who will be engaged from the start of the project. To develop the framework, GRACIOUS will build upon currently available approaches by collating, curating and assimilating existing and new knowledge on intrinsic and extrinsic physicochemical properties in relation to their (environmental) health risk. The resulting framework will support safe innovation by enabling considerations of safety a.o. via grouping and read-across in industrial decision making at various stages of product development. For regulators and policy makers, GRACIOUS will facilitate actual application of grouping and read-across of NMs to enable risk analysis of NM
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Algorithms and systems for multi-baseline sar cross-track interferometry' (1994-1998).

assistant: **Concept**

Research objectives and content Interferometric Synthetic Aperture Radar (InSAR) is a powerful technique for rapid and accurate high-resolution topographic mapping. If two SAR images derived from two spatially separated antennas are considered, their phase difference can be usefully exploited to generate Digital Elevation Maps (DEMs) of the scene under investigation. Among the current problems of this not yet mature technique, the interferometric phase equivocation (phase is measured modulo 2pi) and the data noise have a great impact on the achievable performance. Recently Multi-baseline SAR Interferometry techniques have been proposed in the literature, extending the standard single-baseline (two-antenna) InSAR. The aims are solving one of the key problems in InSAR, the reduction of the errors in the unwrapping of the interferometric phase, and enhancing height estimation accuracy. In fact, the baseline length affects height estimation accuracy and phase unwrapping complexity. The availability of a set of different baselines and a proper processing may achieve the following goals: absolute phase retrieval, improved estimation accuracy and reduced phase aliasing, moreover adaptivity to varying look angle and local terrain slope, and reduction of the blind angles. The current Multi-baseline techniques are still based on sub-optimal signal processing algorithms, and are tailored just to repeat-pass satellite systems. The great potential of the Multi-baseline methodology has not yet been fully exploited. The objective of this project is twofold. First, to synthesize statistically optimal signal processors for exploting entirely the additional information available at the multiple baselines. Second, to study the possible extension of the Multi-baseline data acquisition to s
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Mechanics and multi-physics of phase transformations in shape memory alloys under extreme dynamic environments' (MultiPhaseXtrM) targeting Horizon Europe.

assistant: **Abstract**

Efficient power generation/absorption will remain a crucial aspect of disruptive technology in a society with rising energy demands for sustenance (e.g., power generation) to scientific curiosity (e.g., space exploration). Multi-functional shape memory alloys (SMAs) form the core of many such technological breakthroughs. The multi-functionality of SMAs originates from solid-solid phase transformations, i.e., changes in the atomic lattice structure, driven by local mechanical, thermal or magnetic fields. Project MultiPhaseXtrM identifies a radically different and unexplored regime for the operation of SMAs — large, multiaxial dynamic impact and shock stresses (up to 10 GPa) within short time scales (down to nanoseconds), referred to as “extreme dynamic environments”. Exploiting multi-physical coupling in SMAs under these extreme conditions could scale up their power conversion capabilities by orders of magnitude. Two broad scientific questions form the core of Project MultiPhaseXtrM: (1) How do thermodynamic states evolve in SMAs under extreme dynamic environments and coupled thermal/magnetic fields? (2) How do these states drive the evolution of phase transformations at short time scales? Dynamic impact experiments and high-speed instrumentation, developed in house, will probe this multi-scale behavior in single-crystal SMAs under carefully-controlled strain rates and multi-axial stress states, while advancing experimental science towards resolving short length and time scales, simultaneously. Multi-scale data sets will be analysed within continuum theoretical frameworks to discover the kinetic laws for phase transformations across the range of multi-physical conditions explored. The impact of this program will extend beyond, from designing multi-ferroic SMAs with progr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'EFFECT OF NATURAL VIRAL RNA SEQUENCE VARIATION ON INFLUENZA VIRUS RNA FUNCTION' to be submitted under Seventh Framework.

assistant: **Abstract**

Influenza A virus has an amazing ability to rapidly change its properties. We believe that pathogenic properties of an influenza virus could be determined also by differences in influenza virus RNA sequence that do not affect the protein sequence of the virus genome. In other words, sequences that affect structure and/or function of the viral RNA, could themselves contribute to the pathogenic properties of the influenza A virus, as well as its ability to adopt to a new host. All RNAs in a cell are associated with proteins and RNAs are dependent on these interactions to function efficiently. Interactions of RNA with proteins depend on the RNA sequence and secondary structure. The exact RNA sequence is therefore of paramount importance since it affects secondary structure and function and utilisation efficiencies of the viral RNAs. RNA sequence has a direct effect on mRNA splicing, mRNA stability and translation. The exact sequence of the influenza virus RNA should therefore affect the replication efficiency of each virus strain. It is reasonable to speculate that RNA sequence variation itself can affect virus pathogenic properties. The immediate goal of this short, 2-year project is therefore to investigate if naturally occurring RNA sequence variations in various influenza virus isolates with different pathogenic properties affect influenza virus RNA structure and function. The long-term goal with this project, which reaches past this 2-year period applied for here, is to determine if the influenza virus RNA sequence itself, independently of effects on viral protein sequence, affects viral pathogenesis and tropism.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Strengthening the Research Potential of IMGGE through Reinforcement of Biomedical Science of Rare Diseases in Serbia – en route for innovation' (SERBORDISINN).

assistant: **Concept**

SERBORDISinn will enable IMGGE to become the most recognizable molecular genetic (MG) centre in the Balkans. IMGGE is the leading Serbian MG research institution, employing scientists with the highest expertise in molecular biology and molecular genetics. Research in the field of biomedical science of rare diseases (RD) is a major interest of IMGGE’s Laboratory for Molecular Hematology, Laboratory for Molecular Biology, Laboratory for Human Molecular Genetics and Laboratory for Molecular Genetics of Industrial Microorganisms. EU partnering organizations and EU experts, well known for their excellence in the topics related to SERBORDISinn, will be actively involved in the realization of the Project. Consequently, exchange of expertise and experience related to RD would intensify the transfer of knowledge from distinguished EU centers to IMGGE, enabling the implementation of cutting-edge MG approaches for the study of molecular markers of RD. Furthermore, SERBORDISinn will reinforce the establishment of Serbian and Balkan RD-specific databases and biobanks. Building a strong network with medical institutions and adopting protocols for high quality sample handling will facilitate the integration of IMGGE into the European initiative to build a biobank network. State-of-the-art methodologies in biomedical studies and RD biobanks will set up the basis for functional studies of human mutations. This will enable the identification of potential targets, which, in collaboration with an SME, will lead to designing cost-effective diagnostic test kit(s), pushing IMGGE towards innovations, and paving the path to the application of genome-based medicine. The local network to be established, NIRBOS (Research Initiative for RD in Serbia or Naucna Inicijativa za Retke Bolesti u Srbiji,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'The magnetism of the chromosphere: combining theory and observations' (CHROMAG) targeting Seventh Framework.

assistant: **Abstract**

H-alpha spectroheliograms revealed already in the early twentieth century the beauty and the huge variety of magnetic structures in the chromosphere. However, a comprehensive description of this important layer, coupling the photosphere to the corona, is still missing. The key for a deeper understanding of the chromosphere lies in the reliable determination of the vector magnetic field. The low magnetic field strengths combined with the complexity of non-LTE line formation require a close interplay between advanced atomic physics involving modeling and sophisticated observational techniques and instrumentation.  This proposal addresses the problem of measuring the magnetic field topology in the chromosphere. The applicant's knowledge on the theory of the scattering polarization and its modification due to the Hanle effect will be combined with observational data, analysis methods and powerful inversion codes available at the MPS. Therefore, the applicant and host organization will form a symbiotic partnership.  The equipment of the host to achieve the goals of the project is excellent: MPS has access to powerful workstation clusters. As a partner institute of the German solar telescopes on Tenerife, MPS has guaranteed observing time. Knowledge on data analysis and inversion techniques is excellent. Including the applicant's experience in Hanle diagnostics will result in a fruitful and productive cooperation and open excellent career opportunities to the applicant.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Ecotoxicological Risk Assessment of Sewage Sludge Application in Land Use – Impacts on Terrestrial Organisms and Derivation of Risk Thresholds for Emerging PFAS (SafeSludge)' (SafeSludge).

assistant: **Innovation**

This project (SafeSludge) addresses critical regulatory and environmental challenges linked to the reuse of sewage sludge, with a particular focus on per- and polyfluoroalkyl substances (PFAS), a group of highly persistent and under-regulated contaminants. Although nature-based systems such as sludge treatment reed beds (STRBs) are increasingly used in Europe, especially in Denmark, knowledge of the occurrence, transformation, and ecological risks of PFAS in sludge and amended soils remains scarce, leaving a significant regulatory gap.The project pursues three main objectives: (i) characterize the occurrence, chemical diversity, and variability of emerging PFAS in STRB-treated sludge using non-targeted screening, (ii) elucidate their environmental fate, transformation pathways, and biological interactions in sludge–soil systems through controlled microcosm experiments with plants, earthworms, and soil microbial communities, and (iii) derive ecotoxicological thresholds and develop predictive risk models to inform safe sludge reuse and regulatory standards.To achieve these goals, the research integrates advanced chemical analytics (LC-HRMS, LC-MS/MS), MALDI-MSI, ecotoxicological bioassays, molecular microbiology, and environmental risk modelling. The outcomes will deliver the first robust baseline on emerging PFAS in STRBs, provide mechanistic insights into their fate and impacts on terrestrial organisms, and establish science-based thresholds to guide EU policy development.This project directly supports the MSCA Work Programme, advancing excellence in interdisciplinary research, promoting sustainable circular resource use, and contributing to the EU Green Deal, the Circular Economy Action Plan, and the Soil Health Strategy.


**Keywords:** Ecotoxicity, Risk assessment, S
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Magnetic Hybrid Metal-Organic Interfaces', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

MagicFACE deals on the design and investigation of magnetic hybrid metal-organic interfaces by evaporation of organic molecules (phthalocyanines, porphyrins and single molecular magnets) on non-conventional ferromagnetic surface- confined alloys, which contain rare earths atoms and noble metals (Ag and Au). The project aims to give a full description of the electronic and magnetic interaction phenomena that takes places at the hybrid metalorganic interface, exploring the possibility to create highly spin-polarized surfaces to enhance the performance of quantum information processing and organic spintronic devices. Several spectroscopies and microscopies are combined to obtain a comprehensive understanding on how the hybrid metal-organic interface forms and which kind of electronic and magnetic properties it displays. The preparation of the interface will be carried out under ultra-high vacuum conditions and the structure and morphology will be analyzed using Scanning Tunneling Microscopy and Low Energy Electron Diffraction. The electronic characterization includes local Scanning Tunneling Spectroscopy, spatially averaged Photoelectron Spectroscopy and X-ray absorption Spectroscopy. The main goal is to understand the chemistry and the physical processes taking place at the interface: charge transfer, energy level alignment and hybridization effects. Moreover, the study of the magnetic behaviour of the interface will be carried out by means of Spin Polarized Angle Resolved Photoemission and X-ray Magnetic Circular Dichroism, trying to find the effect of the magnetic coupling between the ferromagnetic substrate and organic molecular layer on the spin-dependent electronic properties at the interface.


**Keywords:** hybrid Interface, molecular physics, surface magnetism, el