RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Advanced Hybrid Mechatronic Materials for ultra precise and high performance machining systems design' (HYMM).

assistant: **Concept**

The ever growing competition on the international markets pushes manufacturers towards shorter design cycles and decreasing manufacturing times and costs for their products. This trend generates a demand for smart, flexible and faster machining systems, easy to set up and configure, which are able to drastically reduce machining time, while improving the final accuracy. Machine axis acceleration of speed 3-5 times higher than conventional ones together with machining accuracy in the range of 0.5-1 µm will be the most probable targets of the new generation of machining systems inside manufacturing shops. Inertial forces, dynamic vibration and stability problems arising from such an accelerations will be so big that, if no suitable solutions are provided, the precision and machining quality will be definitely endangered. Strong mass reduction of mobile machine parts together with the increasing of their stiffness and damping to get excellent static, dynamic and thermal stability of the structures is becoming a 'must', to ensure a technological and cost-effective achievement of such an ambitious goals. Conventional materials for building machine tools are commonly cast iron, welded steel and income case aluminium-alloy. Recently, especially in some running EU projects studies have been carried out to introduce polymeric matrix composites (PMC-fibbers reinforced) materials, aluminium Honeycomb and glued structures. Even if good results in term of mass reduction and damping increasing seem to be achieved within such a projects, this will be absolutely not enough to get the declared excellent technological machine performances. The research will be focused on new materials for macro scale applications to reach a full and deep integration between structural and macaroni parts
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Automating professional TV production for sports'.

assistant: **Innovation**

We developed TiiVii, a fully-automated, professional TV production platform, to help any sports club, league or federation to create their own scalable TV channels with live and on-demand content. At only 10% the cost of a traditionally-televised event, sport organizations will persuasively engage fans and commercial sponsors through interactive sport content. Our solution will create a new value chain that makes TV production available and affordable for non-premium sport segments, and their emerging content distributors - challenger telecom operators and publicly-financed local media broadcasters. Commercial TV sports production can cost up to €100K a game and 95% of European sports club competitions are never seen in a format accessible to their fans. Premium sports dominate all sponsor funding and media attention. The minority federations forfeit their digital media rights to more powerful parties to get any media exposure. Despite widely-connected mobile devices, sport fans have no access their favourite sports live. So far, the market has been applying single-stack artificial intelligence (AI) and ‘stitching’ of multiple camera video inputs. Niche sport codes are promoted with new video content but at no point does it satisfy the high-quality benchmark of professional TV production. The stitched stream with cropped sequences does not show 100% of what actually happens in the game. The result is a non-interactive, non-immersive stream that excludes the emerging technologies designed to support virtual reality and 3D experiences. We will progress TiiVii to a fully-automated production platform through a triple-AI-stack simulating a human production crew operating multi-camera rigs. We will build support for 8K cameras and implement 5G network interoperability to sup
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'In-mouth drilling robots for automating tooth repair and scaling dentist revenues'.

assistant: **Innovation**

Dental caries and severe periodontal disease are major contributors to the loss of natural teeth. About 30% of Europeans aged 65–74 years have no natural teeth which reduce their function and quality of life. Nowadays, the most commonly used teeth replacement procedures are prosthetics and implants. While prosthetics are more affordable and versatile, when they require the reshaping of the teeth the procedure can take longer and there is a higher risk of malpractice because of the inaccuracies of the manual procedure. This can cause various side effects from a less durable prosthesis to the loss of the teeth. DentistRobot Ltd was set up with the main aim to eliminate the inaccuracies by introducing robot technology to the dental industry with our combined software and hardware solution that has been protected with a copyright. It simplifies and improves the process of several teeth replacement procedures reducing the chance of malpractice and improving the patient's satisfaction while increases the number of patients served during a given time. Right now we have a working prototype, and we want to test the procedure in a real patient's mouth. We intend to enter the market within 2 years. To achieve our goals, we have to re-evaluate some of our technical decisions as well as our market researches. We also would like to extend our knowledge about the current legislation processes within the European Union (and beyond). In order to enter the market fast and to be able to supply the demand we are considering making partnerships with manufacturing and distributor companies.For this reason we have decided to apply for the SME Instrument Phase 1 program. With this extended knowledge, we aim to submit a Phase 2 project to develop and implement a production line for the robot an
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Multi-component interventions to reducing unhealthy diets and physical inactivity among adolescents in sub-Saharan Africa' (Generation-H) under Horizon Europe.

assistant: **Objectives**

The fragile health systems in urban sub-Saharan Africa (SSA) are already overwhelmed with NCDs. Despite this, the implementation of the evidence-based WHO Best Buys policies for NCDs prevention in the African region has been found to be off-track. Additionally, less attention has been given to adolescents and yet this is a period in life where behavioural patterns of NCDs risk factors are established and track into adulthood. There is also a gap in our understanding on how to implement and scale up effective diet and physical activity interventions in real world settings in SSA.Our project therefore aims to reduce two important modifiable risk factors for NCDs: unhealthy diets and physical inactivity and their underlying social determinants among adolescents (aged 10-19 years) living in  mixed socio-economic urban communities in two SSA countries (Ghana & Kenya) by designing, deploying, and evaluating strategies for implementation of evidenced and theory based interventions mapped on to the WHO Best Buys. We selected the two countries because they represent different cultural contexts of nutrition transition (East and West Africa), and both countries are undergoing rapid economic development, urbanisation and increases in NCD prevalence. The intervention delivery will take a multi-sectoral approach to increasing the capability, opportunity and motivation of adolescents to eat healthier and be more physically active. We will focus on three settings to enhance the reach: secondary schools and, family/community/faith-based settings and the digital environment using social media. Together, this project will increase opportunities, awareness, knowledge and health literacy, motivate adolescents to increase self-efficacy, guide self-regulatory actions and adopt positive health
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Advancing Black Sea Research and Innovation to Co-Develop Blue Growth within Resilient Ecosystems' to be submitted under Horizon 2020.

assistant: **Abstract**

The Black Sea’s unique ecosystem services are degrading and need to be better managed for the benefit of citizens dependent upon their sustainability. As a critical contribution to the science-based policy needed to preserve the Black Sea ecosystems, BRIDGE-BS proposes a multidisciplinary, multisectoral program building on regional and international initiatives. The project will develop predictive tools and capabilities necessary to understand and predict the impacts of climate-driven and anthropogenic multi-stressors on the services stemming from Black Sea ecosystems. These services and their responses to stressors will be mapped, monitored and modeled in order to identify a safe operating space within which a sustainable blue economy can flourish. To this end, BRIDGE-BS is structured around “three” interconnected nodes: Service Dynamics, Blue Growth Incubators and Empowered Citizens.  Node1 will, using time series and new data, simulations and machine learning tools assess, predict and determine ecosystem resilience to deliver adaptive management tools. Node1 outputs will be used in Node2 to identify services that can support sustainable Blue Growth in the Black Sea by strengthening of resource management, developing and applying innovative technologies as well as supporting innovative start-ups and business models to create added value and jobs. Node3 will support policy uptake of BRIDGE-BS science and innovation results. It will train and strengthen collaborations between scientists and stakeholders, as well as policy makers, industry representatives and societal interest groups. It will educate, train and stimulate interactions between the public, future generations of marine scientists and entrepreneurs as well as motivate and engage policy-makers. Most importantl
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'REwiring the nucleus TowaRds plant ImmuNity'.

assistant: **Innovation**

Plant pathogenic microbes cause significant economic damage to global food crop production systems. Pathogens are specialised microbes that manipulate the host defense circuitry to suppress immunity and promote virulence. Interestingly, many of the processes that determine immunity or susceptible interactions, take place in the host nucleus. With the identification of vast repertoires of (nuclear) secreted pathogen proteins (effectors) and host signaling components that extert their functions in the nucleus, this host compartment is now considered an important interface where outcomes are decided.This proposal aims to unravel the molecular mechanisms that underpin infection outcomes in the nucleus. A powerfull approach that will combine quantitative proteomics with gene expression analyses will be used to (i) detect pathogen effectors in the host nucleus in situ and (ii) identify changes in the nuclear proteome during infection. I will then use Yeast two Hybrid and immunoprecipitation to identify effector host targets before placing these components in a nuclear immune signalling context. New information on effector-induced changes in the host nuclear proteome coupled to immune signalling, will then be used to rationalise implementation of two synthetic approaches towards resistance.I will design synthetic (non)host targets that are immune to effector induced modifications and function towards immunity. In addition, identification of key effectors and targets will be used to design new R-gene like specificities, embodied in synthetic Nucleotide-Binding Leucine Rich Repeat proteins (sNB-LRR).  Overall, this work will impact studies on host-microbe interactions and importantly, will provide proof of concept for two new synthetic breeding strategies in plants.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Rapid mass loss of debris covered glaciers in High Mountain Asia'.

assistant: **Innovation**

The research proposed uses an integrated data-modelling approach to elucidate the role that debris-covered glaciers play in the water cycle of High Mountain Asia (HMA) and establish how future HMA glacier and runoff will evolve. Debris-covered glaciers are of great significance for the hydrology of HMA, with large contributions to headwater streamflow. Despite this, their mass balance, hydrological role and future changes are poorly constrained, challenging model predictions of future water resources. Debris mantles insulate the ice and reduce ablation, but large-scale research indicates that HMA debris-covered glaciers are losing mass at rates similar to debris-free glaciers. This anomalous behaviour has profound implications for future glacier mass balance and runoff, but has not been reproduced with models, a fundamental limitation to a global assessment. I aim to establish that: 1) supraglacial cliffs and ponds are responsible for higher than expected mass losses of HMA debris-covered glaciers, because they act as windows of energy transfer through the debris; and that 2) their inclusion into models of glacier evolution will provide essential new estimates of glacier changes and future water availability in HMA. RAVEN will achieve these aims through combination of high-resolution satellite observations, field data and physically-based models in four sites along the Himalayan arc. This unprecedented setup captures the variety of climate and glaciers across HMA. Using satellite images I will investigate the spatial distribution and temporal evolution of cliffs and ponds; the insights will be used to develop physically-based models of cliff and pond ablation, which will be included in a glacio-hydrological model. Future glacier and runoff response will be projected usi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Unravelling the cellular machinery and triggers for autophagy-mediated Nuclear Pore Complex degradation in yeast' (QualityNPC) targeting Horizon Europe.

assistant: **Abstract**

The nucleus, surrounded by the nuclear envelope (NE), houses genetic material, and nuclear pore complexes (NPCs) mediate the selective passage of molecules between the nucleus and the cytoplasm. NPCs are critical for cellular functions such as protein synthesis and cell division. Dysfunction of NPCs is associated with ageing and disease, highlighting the importance of quality control mechanisms such as NPC degradation. However, the pathways that control NPC degradation remain largely uncharacterized.A recent study in yeast revealed for the first time a selective autophagy pathway responsible for the degradation of fully assembled NPCs embedded in the NE. NE-derived NPC-containing vesicles are engulfed by an autophagosome through the initial binding of Atg8 to the cytoplasmic-facing Nup159. Although Nup159 is present in all NPCs, NPC degradation occurs rarely under normal conditions and is only upregulated under stress conditions such as starvation, indicating a tightly regulated process. This research, using Saccharomyces cerevisiae as a model, aims to uncover the machinery and triggers that regulate autophagic NPC degradation through two main objectives. First, to identify the machinery required for the formation of NPC-containing vesicles, using a powerful combination of genome-wide screening and structural insights from cryo-electron tomography. Second, to determine the mechanisms that trigger the formation of NPC-containing vesicles, focusing on two likely triggers: NPC clustering and nuclear content. The results of this study will redefine our knowledge of NPC quality control and the autophagic degradation pathway for NPCs. The knowledge gained from processes in yeast can potentially be extended to human cell biology, where NPC integrity is crucial in ageing and di
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Pathways towards a fair, inclusive and innovative Data Economy for Sustainable Food Systems' (Data4Food2030).

assistant: **Concept**

The digital transformation of food systems has entered a twilight zone: data-driven innovations have proven to be promising, but it is still unclear how to upscale adoption and have broader acceptance. The Data4Food2030 project aims to improve the data economy for food systems (DE4FS) by expanding its definition, mapping its development, performance and impact to create new insights and opportunities. This contributes to a more competitive and sustainable food system in the EU and supports implementation and adaptation of relevant policies such as a Digital Single Market, Green Deal and the Common Agricultural Policy. Data4Food2030 is a 4-year project that aims to 1) enlarge the knowledge base and insight into the DE4FS, 2) develop a system that monitors and evaluates the development, performance and impact of the DE4FS on relevant EU policies 3) identify drivers and barriers and turn these into opportunities, recommendations and solutions, 4) test solutions and evaluate recommendations in case studies and through stakeholder dialogues and 5) provide future scenarios and a roadmap and sustain the monitoring system to support policy development and accelerate the desired future state of the DE4FS. Data4Food2030’s approach is targeted at an improved future state of the DE4FS from which clear design principles, recommendations and solutions are derived for improving and adapting policies and practices at public and private level. As an essential part of the project, stakeholders are deeply engaged to provide input to various DE4FS concepts and evaluate several project outcomes to increase the impact of the project. Nine case studies provide real-life examples of the DE4FS at micro- and meso-economic level, deploying data and technologies, which are used for mapping and imp
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Exploiting Microbial Glycomimetics to Fight Antimicrobial Resistance' (Glyco-Biotic) targeting Horizon Europe.

assistant: **Abstract**

Antimicrobial resistance (AMR) represents a significant health and economic challenge worldwide. Due to the fact that bacterial infections affect most people at some point in their lives, methods for specific recognition and targeting of bacteria are of key importance in developing approaches to counter the growth of AMR, where the discovery of novel antibiotics represents a global challenge in urinary tract infections (UTI). Progress in bioorganic synthesis has provided access to knowledge of the interactions between receptors (lectins) and specific carbohydrate on the outer membrane of bacteria. Cell surface carboAntimicrobial resistance (AMR) represents a significant health and economic challenge worldwide, where the discovery of novel antibiotics represents a global challenge in urinary tract infections (UTI). Progress in bioorganic synthesis has provided access to knowledge of the interactions between receptors (lectins) and specific carbohydrate on the outer membrane of bacteria. It is commonly accepted that this process requires an exquisite carbohydrate specificity of bacterial surface lectins and offer an opportunity to develop very selective probes that could target specific bacteria by the development of glycan mimics as potential drug candidates. Interestingly, some bacterial strains of E. coli are specific for galabiose. In order to design a drug candidate, it will be synthesized various glycomimetics with a common core of galabiose, which will be conjugated with a fluorescence probe to evaluate their binding affinity. Our hypothesis in this project resolves around the generation of a new class of antibiotics through the combination of known antibiotic drugs with the lead glycomimetics and allowing the drug delivery to the desired location. This project aim