RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'SImple and RObust laser source with EU supply chain and Cavity and injection-free Optical parametric oscillator for spaceborne lidar' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

SIROCO (SImple and RObust laser source with EU supply chain and Cavity and injection-free Optical parametric oscillator for spaceborne lidar) aims to reach EU independence for high-power lasers in the eye-safe region. A solution based on wavelength conversion from a 1m laser will be matured, ensuring EU supply chain independence for power laser emission in the 1.5-3m range. Such breakthrough laser will build the foundation of next greenhouse gases (GHG) spaceborne sensors by Integrated Path Differential Absorption Lidar (IPDA), by which GHG of interest can be probed in the 1.6m or 2m eye-safe regions. To meet the stringent spectral, spatial beam, and power properties required, efficient and versatile wavelength converters such as Optical Parametric Oscillators (OPOs) pumped by mature 1m power lasers are key enabling technologies. This is also the approach in the European Methane Remote Sensing Lidar Mission (MERLIN).SIROCO will mature innovative critical optical space technologies to TRL6, including a hybrid fiber/bulk 1m laser combined with a new Backward Wave OPO (BWOPO) concept. This will lead to a simplification shock compared to the state of the art, as no optical cavity is required (higher robustness and easier integration), nor any OPO seed source (higher compactness and simplicity in wavelength control). It will increase EU competitiveness by faster integrated, less risky, more sensitive future space IPDA.SIROCO will develop nonlinear crystals to ensure an EU supply chain, which are key components for various applications (general laser physics, IPDA emitters, quantum applications). Their exploitation path towards future space LIDAR and quantum communications will be delivered through two public technical roadmaps.SIROCO is a 4-year 3MEuros valued action, gather
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Diversity Enhancements for SIEMs' (DiSIEM).

assistant: **Concept**

Security Information and Event Management (SIEM) systems are a fundamental component of the ubiquitous ICT infrastructures that form the backbone of our digital society. These systems are mostly used to monitor infrastructures using many types of sensors and tools and correlate the obtained events to discover possible threats (attacks, vulnerabilities, etc.) to the organization. The DiSIEM project aims to enhance existing SIEM systems with diversity-related technology. More specifically, we want to (1) enhance the quality of events collected using a diverse set of sensors and novel anomaly detectors, (2) add support for collecting infrastructure-related information from open-source intelligence data available on diverse sources from the internet, (3) create new ways for visualising the information collected in the SIEM and provide high-level security metrics and models for improving security-related decision project, and (4) allow the use of multiple storage clouds for secure long-term archival of the raw events feed to the SIEM. Given the high costs of deployment of SIEM infrastructures, all these enhancements will be developed in a SIEM-independent way, as extensions to currently available systems, and will be validated through the deployed in three large-scale production environments.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Indigenous Psycholinguistics - Tracking Reference Across Cognition' (IndiPsych-TRAC) under Horizon Europe.

assistant: **Objectives**

This proposal addresses fundamental open questions about how language processing uses basic cognitive resources like memory and planning/attentional space. It does so by drawing two languages which are almost completely new to psycholinguistics, Shipibo and Cuzco Quechua, and through them, a new construction, switch-reference, which is also largely unexplored. Although switch-reference is under-explored, it is of interest because current models of linguistic memory and sentence planning suggest that it should be incredibly difficult, and yet it is used productively by speakers of languages throughout the Americas and Oceania. This research therefore moves the needle forward on fundamental questions that address cognitive abilities beyond just language processing, while simultaneously broadening the sample on which psycholinguistic theories are based.While all languages have essentially the same cognitive resources, the different grammatical forms from language to language imply different strategies to use those resources efficiently.  If one of the goals of psycholinguistics is to understand the cognitive resources that are available, and how they can be deployed, this degree of systematic flexibility between the world’s languages is a tremendous scientific resource.  Yet the vast majority of psycholinguistics typically only studies a handful of the largest East Asian languages and a few closely-related European ones, i.e., those that are already in close proximity to scientific laboratories.  This problem is a subset of the one at work throughout psychology: an over-reliance on WEIRD societies (Western Educated Industrialised Rich Democratic; Henrich, Heine, & Norenzayan, 2010). This creates a heavily skewed sample, both in terms of linguistic variety and populations.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Sixth Framework proposal on 'A Systems Approach to Tissue Engineering Processes and Products'.

assistant: **Innovation**

Tissue Engineering is an emerging collection of technologies aimed at the regeneration of tissues and organs. Whilst TE potentiality on healthcare has already been demonstated, there has been a marked lack of link between the different components such that TE cannot deliver its promise at present. STEPS addresses this by introducing a systems approach to TE and associated technologies. Our objective is to provide a new infrastructure, based on the hypothesis that the only way to successfully implement TE is to link together all aspects of this multi-disciplinary process by applying the logistics of systems engineering. Specifically, the technological components will include cell sourcing and manipulation, novel biomaterial development, bioreactor design and the integration of TE constructs into the living host. The programme incorporates a determination of the socio-economic issues related to ethics and health economics. This will include an assessment of the public acceptability of these emerging technologies and the ability of private and public health insurance to pay for it without detracting from more traditional medical procedures. The Consortium has designed an objective-driven approach, set to deliver radical innovations in the long term as well as new processes, methodologies and products in the short and medium term.The potential world market for TE products is estimated at 100 billion and we believe that our approach will transform the TE industrial infrastructure to the point to deliver to this market The Consortium comprises 23 partners from 13 European Countries. It includes 6 industrial organizations (4 SMEs) and 17 academic centres. To develop such a highly innovative systems approach to TE, the contribution of a multidisciplinary Consortium, of a critic
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Centrope ICT Technology Transfer Project', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

The co-operation within the Central European region called Centrope – bordering regions of Austria, Czech Republic, Hungary and Slovakia - should trigger challenges and broaden the circle of experts to build a region that will become a model for European integration process.     The project CITT triggers challenges in the ICT sector by providing a strategy to improve technology transfer between the business and research communities within the Centrope region in order to support its growth.   The project’s backgrounds are several key elements in the area of research driven sectors which weaken a knowledge driven economy:   1) Lack of relevant information and awareness on the side of policy makers especially on a regional level and therefore limited commitment and/or engagement to implement new policy tools.   2)  Centralised system which often do not reflect regional specification.    3)  Barriers in the interaction between business and academia.    In order to overcome national, institutional and mental problems linked to technology transfer in the area of digital technologies, it is the aim of the project to demonstrate their viability in best practice examples and offering a strategy within defined regional limits which should, however, be able to be up scaled to the benefit of the entire Union.    Simultaneously, the project will identify relevant players in ICT industry and R&D which so far have not been categorised in this way. A database containing such information will represent a unique resource valuable to (Central) Europe’s economy.  The project partners will provide solutions for improved technology transfer between the research and business communities as well as for mentoring and coaching of the research and business communities (based on mutual approach).
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Macrophage-based immunotherapy of platinum-resistant ovarian cancer'.

assistant: **Concept**

Resistance to platinum-based chemotherapy is a major clinical challenge in ovarian cancer. About 300,000 women are diagnosed with ovarian cancer each year and the number of deaths is estimated at 180,000 worldwide each year. Ovarian cancer metastasizes early in its development, often before it's diagnosed. Ovarian cancer treatment involves surgery with frontline platinum-based chemotherapy. As many as 15-30% of patients with ovarian cancer have primary platinum-resistant or refractory disease. The recurrence of ovarian cancer is now considered a sign of an incurable disease (it becomes platinum-resistant).The project MACOV aims to develop an innovative allogeneic, “ready-to-use” macrophage-based therapy for platinum-resistant ovarian cancer. This is a ground-breaking, first in class therapy that shows very high efficacy in multiple solid tumors of unmet medical need. These cells are equipped with targeted therapy drugs complexed with the carrier protein ensuring their stability in the carrier cell. The protein-drug complex is transferred specifically to cancer cells. The whole concept of this cell therapy is based on the groundbreaking scientific discoveries of MDC (Macrophage-Drug Conjugate). Two European Research Council (ERC) grants were received to study the molecular basis of the discovered mechanism - in 2016 and 2020. In 2018 this project was selected to be promoted as one of the 10 European projects during ERC 10th Anniversary. The MACOV project will generate of complete efficacy data package for the pre-clinical development of MDC-735 product, consisting of efficacy in multiple  animal models for platinum-resistant ovarian cancer, PK, PD and toxicology study as well as consolidate IP and validate business case. The result of the project will be a validated cell
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Fate of reduced organic sulfur'.

assistant: **Objectives**

Arctic suffers of the global warming and as a consequence ground- and surface waters are more and more mixed, increasing microbial activities. Because roS are present in all living organisms as amino acids (i.e. cysteine and methionine), increasing microbial activities induce increasing production of reduced organic sulfur (roS) and organic matter (OM). Some metals and metalloids (Me) have a large affinity for roS (i.e. Pt2+, Pd2+, Hg2+, Cd2+, As(OH)3, Sb(OH)3), leading to the formation of ros-Me complexes. The presence of roS modifies thus the fate, speciation (i.e. all chemical and physical forms), bioaccumulation and toxicity of Me. Rate of roS and rate of Me are interconnected: aquatic living organisms produce roS in response to Me stress, in order to modify the speciation of Me, which in turn modifies the bioaccumulation and toxicity of Me. Despite the interconnections of Me and S biogeochemical cycles, such roS-Me forms are neither quantified (i) in the environment (i.e. water), (ii) nor in laboratory ecotoxicological studies, (iii) or in ecotoxicological modelling, and (iv) only partly in laboratory geochemical experiments (i.e. only the model I developed in 2015 consider As association to reduced S of OM). In Fate roS, we will elucidate roS-Me associations through analytical developments dedicated to natural waters, which will be able to quantify roS speciation in boreal waters (including high Arctic). Thanks to a coupling of original experimental and spectroscopic results, a toxicogeochemical model will then be developed to predict the toxicity of Me and Me-roS. A successful scientific and training project is expected due to a cleverly thought 3-way-transfer of complementary skills in between me, my supervisors of the host institution (HI) and the partner insti
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'SUPPORTING EUROPEAN COASTAL REGIONS  IN THEIR TRANSITION TO A SUSTAINABLE BLUE BIOECONOMY' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

The Blue Bioeconomy defined as ‘the production and conversion of renewable marine biological resources into value added products, such as food, feed, bio-based products and bioenergy’ entails a large set of opportunities for European coastal communities. Innovative business models based on circularity; short-chains, digital solutions and ecosystem contributions offer the chance to stabilize and create new enterprises and jobs also for the lower-educated; while transforming remote, rural areas also into interesting, revitalized, climate-friendly places to live. However, blue bioeconomy actors struggle with challenges related to technology, lack of knowledge & skills or regulatory barriers. BlueBioClusters brings together 12 support organizations from across Europe, all of them highly engaged in their 9 regions in assisting start-ups, companies and policy makers to make best use of innovations. They have joined forces to improve, develop and implement new support tools and methods based on systematic collection, benchmarking and joint knowledge creation on *blue biobased value chains, practice cases and incentives, WP2; *ecosystem service valorization, WP3; *technology needs, identification and transfer of solutions, WP4; *start-ups/SMEs; experts and support mechanisms (coaching; co-creation), WP5; as well as *‘Communities of Practices’, to foster long-term stakeholder cooperation within and across the regions; WP6. While we expect to create long-lasting impact already within the project lifetime by engaging with hundreds of actors within our regions to stimulate collaboration and actions for change; activities are designed to be continued post-project, being also open for other Blue Regions, clusters and individual companies to join. To that end, the inter-active BlueBio
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Engineering Photoenzymes for New-to-Nature Asymmetric Radical Processes' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

PHOTO-BIO-ENG aims to develop entirely new strategies for the stereoselective synthesis of complex chiral molecules. We will achieve this by combining biocatalysis and photocatalysis to generate photoenzymes for visible-light-driven radical processes. Utilizing directed evolution and high-throughput experimentation, we will create highly efficient and stereoselective photoenzymes capable of catalyzing transformations that are currently inaccessible to small-molecule catalysts and unachievable via ground-state thermal pathways. Our approach will use enzymes as green catalysts and visible light as a renewable energy source, with environmentally benign reaction conditions (ambient temperatures, aqueous solvents). By merging photochemical methodology with enzyme catalysis, we aim to demonstrate novel chemical transformations that produce chiral products with multiple stereocenters and excellent stereocontrol. This project will establish a highly effective and sustainable synthetic methodology, contributing to the advancement of green chemistry practices.Collaboration with Johnson & Johnson will facilitate the development of photoenzymatic processes to yield chiral molecules with biologically relevant scaffolds. PHOTO-BIO-ENG combines the fellow’s experience in enzymatic catalysis and directed evolution with the host’s expertise in photo-triggered asymmetric radical processes. The interdisciplinary nature of the project will significantly enhance the fellow's expertise, providing comprehensive training and positioning them strongly for future career advancements.


**Keywords:** biocatalysis,  asymmetric catalysis,  iminium ions,  radical chemistry,  organocatalysis,  photochemistry,  protein engineering
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Distributed MILS for Dependable Information and Communication Infrastructures' (D-MILS), addressing dissemination and exploitation.

assistant: **Impact**

Modern critical systems bear great responsibilities and face escalating challenges. Distributed systems for critical applications are costly and time-consuming to develop and to certify. Since there is little automated support for early assurance that a system faithfully implements its architectural design and satisfies its requirements, qualification testing and certification processes often reveal deficiencies that require costly late changes.<br/>MILS provides compositional system construction and assurance, leveraging individually developed and assured components to predict and assure the properties of composite systems. By providing a modular high-assurance platform and a framework for the certification of systems built on that platform. MILS reduces the cost and time for development, certification, and maintenance of dependable systems.<br/>Distributed MILS relies on extensions to a MILS separation kernel and the addition of a MILS network subsystem using a hardware-based, time-triggered Ethernet backplane". It will be possible, for the first time, for an application architecture to seamlessly span multiple computer systems, with scalable deterministic operation over a set of nodes, opening many new practical application areas for MILS.<br/>Automated assistance, as being developed and applied in this project, is indispensable for the development and verification of dependable distributed systems. System architects, developers, integrators, installers, operators, and particularly the organizations and populations that depend on critical systems, will benefit from the resulting assurances that many of the sources of errors that lead to added cost and dangerous failures of critical systems can be eliminated.<br/>Results of the Distributed MILS project will establish