RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Intelligent Ultraviolet (UV) Radiation Filters' to be submitted under Horizon 2020.

assistant: **Abstract**

3 million non-melanoma skin cancers and 132,000 melanoma skin cancers occur globally each year, of which about 65% to 95% of cases are related to sun exposure and a history of sunburn. Prevention tools are shade, clothes, hats and sunscreens.Ultraviolet (UV) filters are the sunscreens active ingredients that absorb the radiation. There is no fixed time that we can be exposed to the sun without developing sunburn, it depends on the irradiation to which we are being subjected, which varies according to the time of day, latitude, season and the activity that is being done.Existing sunscreens do not adjust to the radiation dose that reaches the skin; they degrade quickly as they absorb more radiation, therefore offering less protection during a given exposure time. In addition, none of the existing filters can generate enough protection alone in one formulation; they must be formulated in combination with other UV filters to produce reach the sun protection factor (SPF).These combinations produce compounds that are responsible for the discoloration and subsequent death of corals.Roka Furadada (Roka) has developed SMART UV, intelligent UV filters that are activated by a minimal dose of harmless radiation and are able to respond to high doses of radiation while maintaining protection over long periods of time. SMART UV offers all day, sun protection of SPF 30, without the need to be combined with other filters. SMART UV filters produce significantly less environmental damage.SMART UV: Better for human health, better for the environment.Sales volume of UV filters will reach over 50,000 tons and will be equivalent to a turnover of 1,815 billion euros, with a growth of 3.1% of CAGR by 2022.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Trapping Ions in Atoms and Molecules Optically' (TIAMO) targeting Horizon 2020.

assistant: **Abstract**

Isolating ions and atoms from the environment is essential in experiments on a quantum level. For decades, this has been achieved by trapping ions with radiofrequency (rf) fields and neutral particles with optical fields. Our group demonstrated the trapping of ions by interaction with light. We see these results and our proposal as starting point for finally combining the advantages of optical trapping and ions. In particular, ions provide individual addressability, high fidelities of operations and long-range Coulomb interaction, significantly larger compared to those of atoms and moleculesThe aim of this proposal is to (i) study and establish optically trapping of ions and atoms in general, to (ii) demonstrate the substantial improvement of our approach in the context of interaction and reaction at ultra-low temperatures and to (iii) explore further perspectives by adapting methodology of quantum optics to gain control and state-sensitive detection on the level of individual quanta within the merged ion-atom system. The field of ultra cold chemistry is perfectly suited as a showcase for this purpose. We will embed optically trapped ions into quantum degenerate gases to reach temperatures, 4-5 orders of magnitude below the current state of the art. Our approach circumvents the currently inevitable excess kinetic energy in hybrid traps, where ions are kept but also driven by rf-fields. It permits to enter the temperature regime where quantum effects are predicted to dominate, (i) in many-body physics, including the potential formation and dynamics of mesoscopic clusters of atoms of a Bose-Einstein-Condensate, binding to the “impurity ion”, as well as (ii) the subsequent two-particle s-wave collisions, the ultimate limit in ultra-cold chemistry.Further development of our
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Pheromone Identification for Environmentally Responsible Control of Thrips', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Thrips are insects that are important crop pests in agriculture and horticulture. They cause most damage to protected (greenhouse) crops, which have an annual EU production of 37 billion euros. Growers are struggling to control thrips but are also under pressure to reduce pesticide use. The EU Directive on the Sustainable Use of Pesticides (2009) requires alternatives to pesticides to be used wherever possible. There is also the imminent threat that an invasive species, Thrips palmi, will devastate protected crops when it reaches the EU.This is a multi-disciplinary project that uses skills in biology and organic chemistry to improve crop protection in agriculture and horticulture by developing new methods for the monitoring and control of thrips. Aggregation pheromones of thrips can be used to monitor thrips populations so that pesticides are only applied when necessary and also to modify behaviour to enhance the effectiveness of control methods. The project will identify the aggregation pheromone of Thrips palmi and also make the aggregation pheromones of other pest thrips species easily available for monitoring and control.The project addresses the EU policy objectives of minimising the use of pesticides and promoting sustainable horticultural production methods that meet consumer requirements for a safe food supply chain and environmentally responsible growing systems.The success of the project depends on bringing together complementary skills. The MC fellow has significant skills in the organic chemistry of natural products, while the Keele group has considerable expertise in thrips biology, chemical ecology and the translation of research results into practical outcomes for horticulture.This research will develop an environmentally responsible method of monitoring
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Electro-motion for the sustainable recovery of high-value nutrients from waste water' in the context of a Horizon 2020 call.

assistant: **Objectives**

Current water treatment technologies are mainly aimed to improve the quality of water. High-value nutrients, like nitrate and phosphate ions, often remain present in waste streams. Electro-driven separation processes offer a sustainable way to recover these nutrients. Ion-selective polymer membranes are a strong candidate to achieve selectivity in such processes.The aim of E-motion is to chemically modify porous electrodes with membranes to introduce selectivity in electro-driven separation processes. New, ultrathin ion-selective films will be designed, synthesized and characterized. The films will be made by successively adsorbing polycations and polyanions onto the electrodes. Selectivity will be introduced by the incorporation of ion-selective receptors. The adsorbed multilayer films will be studied in detail regarding their stability, selectivity and transport properties under varying experimental conditions of salinity, pH and applied electrical field, both under adsorption and desorption conditions.The first main challenge is to optimize and to understand the film architecture in terms of 1) stability towards an electrical field, 2) ability to facilitate ion transport. Also the influence of ion charge and ion size on the transport dynamics will be addressed. The focus of E-motion is set on phosphate ions, which is rather complex due to their large size, pH-dependent speciation and the development of phosphate-selective materials. Theoretical modelling of the solubility equilibria and electrical double layers will be pursued to frame the details of the electrosorption of phosphate.E-motion represents a major step forward in the selective recovery of nutrients from water in a cost-effective, chemical-free way at high removal efficiency. The proposed surface modifica
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Towards an e-infrastructure Roadmap for Open Science in Agriculture' to be submitted under Horizon 2020.

assistant: **Abstract**

The strategic goal of e-ROSA is to provide guidance to EU policies by designing and laying the groundwork for a long-term programme aiming at achieving an e-infrastructure for open science in agriculture that would position Europe as a major global player at the forefront of research and innovation in this area. Through a foresight approach, the project will build a shared vision of a future sustainable e-infrastructure for research and education in agriculture and make it operable through pragmatic recommendations that will be reflected in a common roadmap.This will be achieved through a process of co-design, involving mainly research and education communities but also practitioners and EU policy makers, and will build on the existing projects, networks, international alliances or initiatives that the project will systematically map and integrate in the analysis of grand challenges ahead and the identification of priorities and solutions towards an open, digital and data-intensive science in agriculture.


**Keywords:** Open Science, agriculture, food, e-infrastructure, research and education, roadmap, vision, foresight, societal challenges
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Tracing European Copper Age Social Dynamics through Pottery Technology and Use'.

assistant: **Objectives**

TraCTUs aims to investigate the social dynamics of European prehistoric communities between the 4th and the 3rd millennium BC, studying the phenomenon of craft specialization through an integrated approach of theoretical and empirical analyses.The Copper Age represents a crucial period in human history during which the first forms of social complexity begin to develop; for this reason TraCTUs identified a context, as the Rome area (Italy), where numerous prehistoric clues, dated between the 4th and 3rd millennium BC, suggest the existence of social diversifications. These evidence can be reflected in the organization of pottery production, indicating the emergence of specialised artisans as new social identities. In a second step of research, TraCTUs will contextualise the data coming from the Copper Age burials of the Rome area, in a broader European framework in order to highlight patterns of similarities or diversifications in social dynamics and  elaborate models related to social complexity of Copper Age communities. So far, several scholars investigated specialisation and elaborated models based on a scale of intensity. However, such assumptions derive only from limited empirical datasets. TraCTUs instead, proposes a further contribute to the discipline, applying a methodological approach integrating social theories, diffused in Anglo-American studies, with a detailed empirical investigation performed through a multi-analytical study of direct and indirect evidences related to the organization of pottery production.The research will be conducted at McDonald Institute for archaeological research in Cambridge University, where the candidate will receive a high level training in archaeological and anthropological theories and statistical data treatment that will allo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Intestinal stem cells and their role in colorectal cancer progression' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

Constitutive activation of the Wnt pathway is the key step for initiation of colorectal cancer (CRC). Wnt signaling also plays an essential role in the maintenance of intestinal stem cells (ISCs). In addition, acquisition of a constitutive crypt stem/progenitor phenotype represents the first step towards malignancy. The identification of the Wnt target gene Lgr5 as a marker for ISCs and the finding that Lgr5+ ISCs represent the origin of intestinal cancer suggest that specific features of ISC are required to initiate CRC. Given the critical role of ISCs in CRC onset, we intend to study their contribution to CRC progression, tumor recurrence, and metastasis. Characterization of Lgr5+ CRC cells at different disease stages will clarify, which part of the “stemness” genetical program remains conserved during progression of malignancy. We will also address to which extent an Lgr5+ CRC cell residing in a primary tumor or in metastasis resembles a crypt Lgr5+ ISC. To achieve this, progression of intestinal cancer derived from ISCs or differentiated cells will be studied using a novel transgenic mouse model system: Starting from defined, targeted cells which have acquired Wnt activation combined with mutation in KRAS, tumor progression can be tracked by fluorescent proteins concomitantly induced with compound mutations. “State-of the art” flow-cytometry-based sorting techniques will be used to isolate different tumor sub-populations in order to characterize them in detail. Interestingly, only a rare sub-population of tumor cells in CRC patients, so-called “cancer stem cells” (CSCs), is able to re-establish tumor growth in immune-deficient animals. We seek to understand how these tumor-promoting cells are genetically and functionally related to Lgr5+ ISC and Lgr5+ cells in CRC.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Neurogenesis in the female Brain: A link to depression in women' goes beyond current state-of-the-art under Sixth Framework.

assistant: **Innovation**

Women are twice as likely as men to experience depression in their lives, yet the reasons for this sex difference in mental illness are unknown. Recently it has been proposed that neurogenesis, the production of new neurons in the adult brain is involved i n the expression of major depression, although the studies have only been conducted in males. In this project, the research fellow will examine how stress and learning alter the survival of newly generated neurons in the female versus the male hippocampus. Recent studies from the host outgoing institution have shown that learning increased the survival of new neurons. However, exposure to uncontrollable stressful experience dramatically impairs learning in females. Therefore, we propose that uncontrollable but not controllable stress will reduce learning in females and prevent the increase in cell survival, whereas exposure to the stressful event will have no effect on cell survival in males. We further propose that these adverse effects in females can be prevented by chronic treatment with the common antidepressant fluoxetine. Finally, we will determine whether the presence of female sex hormones, estrogen and progesterone are necessary and will also correlate changes in neurogenesis with serotonergic activity/ 5-HT1A receptor expression in the hippocampus. The results from these experiments will provide critical information about how females respond to stress and hopefully will lead to new and improved treatment strategies for women suffering from depression. It is envisaged, that this project will permit the enhancement of the existing expertise, the researcher's transnational mobility and training and the establishment of international cooperation. Thus, it will contribute to European excellence and competitivenes
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Senegalese socio-cultural integration and exclusion in Europe - a study of institutional practices and migrants transnational networks in Emila-Romagna' (1994-1998), addressing dissemination and exploitation.

assistant: **Impact**

This project seeks to assess the efficiency of local policies toward immigrants and to evaluate the integrative capacity of migrants' Own organisations. This will be done through detailed investigation of Senegalese transnational migrants in a specific context within Italy (Emilia Romagna) exploring the interplay of two social phenomena: 1) The everyday life and strategies of immigrants in relating to the host context, and their reliance on transnational networks, based on kinship religious belonging and rooted in the sending context. 2) The representations of immigrants in the local receiving context, and the institutional practices which these imply. In doing so, I will test the historical validity and theoretical viability of categories such as integration" and "exclusion" applied to contemporary post-industrial Europe. Therefore, this case study will be located in a wider, comparative literature concerning France, where other Senegalese immigrants live, thus enabling the research to generate hypotheses about migrants' integration in different EU countries. Training content (objective, benefit and expected impact) Sussex University has a long-term ethnographic tradition, that is lacking in Italy, and the CDE shows a strong interest in migration, social exclusion, identity, representations and practices. These are the reasons why I find in this institution a suitable environment for my training and for my supervision. "
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Scanning force microscopy studies adhesion in combination with adhesive strength and physicochemical characterization' to be submitted under Fourth Framework.

assistant: **Abstract**

Research objectives and content The main objective of this project is to understand the underlying molecular mechanisms of the polymer adhesion by adding the expertise of Dr. Koutsos in Scanning Force Microscopy (SFM) to the other techniques already used in Dr. Leger 's group. The SFM technique will give directly in real space nanoscale information on the structure mechanical properties of polymer surfaces before and after fracture. SFM should be a complementary tool to the techniques used in the group: JKR test, wall slip measurements, X-rays and neutron reflectivity . The general orientation of the research project is to link the adhesion strength between bulk polymers (elastomers or semicrystalline polymers) and surfaces bearing surface connectors which enhance the adhesive properties. One of the systems to be investigated will be incompatible semi crystalline polymers (polypropylene/ polyamide) with connectors in between (which act as compatibilizers), with the objective of getting informations on the polymorphic transformations that possibly occur at the interface during curing and fracture. The other system will be latex films with investigation of their micromechanical properties and surface structure before and after fracture from silica surfaces bearing polymer connectors (brushes or pseudo-brushes) Training content (objective, benefit and expected impact) On one hand Dr. V. Koutsos will extend his expertise in Surface Scanning Microscopy on thin and ultra thin polymer layers to polymer surfaces and solid surfaces after fracture. On the other hand he will be working on a new subject for him: polymer adhesion, using a great variety of techniques of great potential applications. Links with industry / industrial relevance (22) The present project is not linked to
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'From the lab to the plant: large scale manufacture of prostaglandins' in the context of a Seventh Framework call.

assistant: **Objectives**

Prostaglandins (PGs) are hormone-like chemical messengers that regulate a broad range of physiological activities, essential to life. Some synthetic analogues of prostaglandin are ‘billion dollar’ drugs e.g. latanoprost, which is used to treat glaucoma. The whole family of PG drugs (around 30 members) have combined annual sales of >$10bn pa. Furthermore a new dermatological application of PGs against reduction in adipose tissue (i.e. fat) discovered by Topokine is set to dwarf these numbers and, if successful in reaching the market, will require a 1000 fold increase in volume of production of PGs at the minimum. However, since these complex molecules cannot be isolated from natural sources in sufficient quantities, they have to be synthesised (20 steps) at considerable cost. We have developed a dramatically shorter route to this class of compounds (7 steps) which could substantially reduce the cost of manufacture of prostaglandins. Ours is likely to be the world-leading process for manufacture of prostaglandins providing we can make some improvements to the process to make the synthesis workable on large scale and thus attractive to pharmaceutical industries. The technology readiness level is perhaps 3-4/9, and needs to reach 6-7/9 to be taken up by industry. This Proof of Concept will take our synthesis through technology readiness levels 4-6.""