RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Multimedia Scalable 3D for Europe' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

The last decade has seen a revolution in the distribution of motion content: from analogue to digital and then from SDTV to HDTV. Both the delivery and the content creation industries exploited these advances, for the final benefit of consumers. Today, it is widely accepted that the next step is the evolution from HDTV to 3DTV, as indicated by the new industrial fora that appeared in 2008. It has also been recognised that providing 3D to homes requires an abstraction layer decoupling content generation and reproduction in order to allow for adaptation to heterogeneous displays, viewing conditions and user preferences.<br/>MUSCADE will generate major innovations in the fields of production equipment and tools, production, transmission and coding formats allowing technology independent adaptation to any 3D display and transmission of multi-view signals while not exceeding double the data rate of monoscopic TV, and robust transmission schemes for 3DTV over all existing and future broadcast channels.<br/>The major scientific and technological objectives of MUSCADE are to:- define a scalable and generic 3DTV representation format, develop advanced multi-view video coding algorithms scalable in terms of network performances and display capabilities- design and develop an intelligent audio-visual capture and production assistance system performing multi-view configuration and providing calibration and metadata- design and develop advanced versions of spatialised sound in combination with 3D viewing having matched aural and visual cues- investigate and implement techniques for the scalable and robust transmission of 3DTV- design and develop a 3DTV player- develop a 3D video interactive application platform- set-up a complete multi-view scalable 3DTV chain to assess its performa
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Manoeuvring Noise Evaluation Using Validated Rotor State Estimation Systems'.

assistant: **Innovation**

The MANOEUVRES project aims at the demonstration of the feasibility of an innovative approach to noise abatement in rotorcraft terminal manoeuvres based on in-flight measurement of the rotor state. In particular, a novel sensor system for rotor tip-path-plane angle of attack will be designed, developed and tested together with the necessary signal conditioning, in order to assess its capabilities in view of application on production helicopters. This sensor will be integrated on-board an actual helicopter for on-ground demonstrations and validation. Based on the availability of this new sensor, an algorithm will be developed that, together with other vehicle data (such as airspeed), will enable the run-time estimation of the emitted noise.  This algorithm will exploit an acoustic data prediction process resulting from a dedicated study, which includes the analysis of the dependency of acoustic emissions on actual (unsteady) flight conditions as based on steady, quasi-steady and full-unsteady approaches, as well as the examination of the sensitivity of the emitted noise with respect to perturbations of a given trajectory. The results from the acoustic prediction processes considered will be correlated with experimental data provided by the GRC5 consortium. A human-machine interface will be designed according to aeronautical standards to provide useful information to the pilot in terms of emitted noise, allowing for flying low noise procedures with improved awareness and effectiveness. Preliminary testing will be carried out to assess compliance of this noise indicator with piloting requirements. The team involves Politecnico di Milano technical university; University of Roma Tre; Vicoter, a SME specializing in mechanical design, analysis, and testing; and Logic, a SME sp
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Generation of broadly cross neutralising Antibodies for innovative active-passive HIV Vaccination Strategies based on modified Ig-gene transgenic mice' (HIVAB), addressing dissemination and exploitation.

assistant: **Impact**

For improved protection from HIV infection during birth or through accidental exposure to HIV, antibodies with broad neutralizing activity would be a valuable addition to antiretroviral treatment and to vaccines. So far in the field of HIV applied resear ch only few antibodies with broad cross clade neutralizing properties are available (b12, 2G12, 2F5 and 4E10). They recognize either epitopes presented only transiently during infection of cells, or epitopes not recognizable by unmodified immunoglobulins (2G12). Two experimental strategies are used in separate and in combination. One uses the lead given by extremely rare mutant antibody genes (ie 2G12) to generate mice with germ line modified immunoglobulin genes which introduce extended mobility into th e immunoglobulin protein backbone. Immunisation of these mice will allow recognition of novel expanded epitopes including glycane clusters and the development of monoclonal antibody. The other line of experiments employs HIV receptor-transgenic mice for i mmunization to favour receptor mediated transitory stages of the viral envelope. Previous experience and reagents from earlier EU funded programmes (virosome incorporating HIV proteins PN 012183) and new microbicide-vaccine combinations against HIV (subm. call LSH-2004-2.3.0-1 with R. Shattock) to present native oligomeric HIV envelope of clinically relevant HIV isolates will be used in addition to liposome presented recombinant C-clade gp 140 oligomers and gp160 encoding highly effective DNA plasmid vacc ines in CD4 transgenic mice to generate monoclonal antibodies with novel broadly neutralizing properties. This proof of principle can directly give valuable reagents. It can also be further developed into humanized antibodies. The novel antibodies develo ped out of th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Sixth Framework proposal on 'Weak Water vapour Lines Contribution to the absorption of atmospheric radiation'.

assistant: **Concept**

The spectroscopic properties of water vapour are of crucial importance for the understanding of the energy balance in the Earth atmosphere because water is the most important absorber of both incoming and outgoing radiation. However models of atmospheric absorption using available spectroscopic data significantly underestimated the total absorption. Water has many, many weak transitions which are routinely neglected and it is possible that these are responsible for much of the missing absorption.   We will evaluate the contribution of weak water vapour lines to the absorption of solar radiation in the Earth's atmosphere and determine their contribution in different spectral intervals, especially in the atmospheric transparency windows. A new detailed database of water transitions will be created using the latest high quality potential energy and dipole moment surfaces constructed at the host Institute. Precise, synthetic linelists calculated using variational methods, together with calculations performed using an effective Hamiltonian approach will be used to extend the spectroscopic information about H2O absorptions, particularly by weak lines, over a wide spectral region.  In particular, spectroscopic data on isotopically substituted water molecules, such as H218O, H217O and HDO, will be calculated over the entire visible region. This resulting improved database of water transitions will be used in calculations of atmospheric absorption of solar radiation. These calculations will be performed in the wide spectral region from 10000 to 20000 cm-1 and will use a realistic atmospheric model, which includes diffuse light scattering in a cloudless atmosphere. The final result will be the first realistic calculation of atmospheric absorption with accuracy better 1% for a cle
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Plasmon Enhanced Photocatalytic Nano Lithography'.

assistant: **Innovation**

The emergence of nanoscience and nanotechnology, with envisioned applications spanning from nano-optics and nano-photonics, to plasmonics and nano-electronics, depends on the capability to fabricate a variety of nanometre-scale structures. Despite the impressive development in these fields, breakthroughs remain in the laboratory, largely due to technological limitations in the ability to manufacture complex and accurate nanometer-resolved surface patterns, with satisfying resolution and on large area. The development of a new fabrication methodology is thus required.   We propose to develop and demonstrate a novel technique for nanoscale photolithography that would bring 21st century nanotechnology breakthroughs out of the lab and into the public sphere. This technique is based on a chemical mechanism recently discovered in my lab. We revealed that multi-electron photocatalytic reactions could be directed to progress exclusively under a plasmonic field, in a controlled and highly localized manner. In this proposal we describe how this phenomenon may be leveraged for pattering, and high-resolution nano lithography.  The project is divided into 3 stages: 1. Fundamentals of the underlying physical phenomena 2. Probe enhanced photocatalytic writing  3. Photolithography via plasmon enhanced photocatalytic mask  At the end of the 5-year project we expect to be at a position to demonstrate our platform for lithographic writing of an interesting nano pattern of high quality, and establish the potential of this methodology as a powerful instrument in the nanotechnology researcher’s toolbox. I strongly believe that successful implementation of this project would fundamentally change the way in which nanotechnology affects modern life.


**Keywords:** plasmonics, nano-electronics,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Pre-commercialization of new generation Atomic-layer-deposited Lasers for future green high-performance data centers' (A-Laser), addressing dissemination and exploitation.

assistant: **Impact**

The continuous growth of global data traffic pushes the data center technology boundaries and their energy consumption. Data centers already use more than 2% of the global electricity and are expected to consume 20% by 2025. The new generation hyperscale data centers offer a more energy-efficient alternative to conventional data centers but are limited by the current technology restrictions. Silicon photonics has been deemed to solve current bottlenecks for building green hyperscale data centers. However, this technology is challenged by the complicated and expensive fabrication methods of the laser sources, which represent 40% cost of the entire silicon transceiver market.  Using a simple fabrication method invented in our ERC Advanced project, we have designed a waveguide light source that can be fabricated onto the silicon-integrated platform with a single-step, straightforward, low-cost, low-temperature and scalable process that lowers the fabrication cost ~10 times compared to the state-of-the-art light sources. Such technologic breakthrough will push the implementation of silicon photonics in hyperscale data centers, allowing them to maintain a low energy footprint while meeting the ever-increasing bandwidth requirements of the growing big data societal challenge. Our project aims to further develop the novel technology and demonstrate its effectiveness for data center applications, to create the first-of-its-kind low-cost and scalable fabrication technology for the silicon photonics market, compatible with the current systems used in the industry. Furthermore, we will prepare and validate the business concept with value chain players, strengthen our IPR strategy, and prepare the commercialization to establish a start-up aiming at serving this significantly growin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for ''cause and effect' coupling of fluid flow and brittle-ductile deformation in the storsjoen-edsbyn shear zone, central sweden' (1994-1998).

assistant: **Innovation**

Research objectives and content An emerging consensus among geologists is that fluid released during metamorphism of the Earth's crust is focused through zones of deformed rock. The proposal objective is to investigate apparent 'cause and effect' coupling of metamorphic fluid flow and deformation, which is important because metamorphic fluids can transport heat and matter, thus influencing the thermal and mineralogical properties of the crust. The Precambrian Storsjvn-Edsbyn Deformation Zone (SEDZ), central Sweden, is an ideal 'natural laboratory', for this investigation. In the SEDZ, ductile (high temperature) deformation, associated with anomalous shifts in metamorphic grade, indicative of thermal and/or chemical exchange with metamorphic fluids, precedes brittle (low temperature) deformation, associated with magnetite, gold and graphite mineralisation. The project will be facilitated by (i) quantifying fluid fluxes from transport of relevant 'tracers' according to chromatographic theory, (ii) determining fluid composition from mineral-fluid equilibria and/or fluid inclusions by micro-Raman spectroscopy, and (iii) quantifying deformation, aided by gravity modelling using the unique centrifuge facility at U. Uppsala. Training content (objective, benefit and expected impact) The project integrates numerical modelling of chromatographic systems, analytical isotope geochemistry, equilibrium thermodynamics, micro-Raman spectroscopy, micro-structural analysis and centrifuge gravity modelling, to provide predictive models of coupled deformation and fluid flow. Links with industry / industrial relevance (22) The project is collaborative with Mineral Graphite AB, Edsbyn, Sweden.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'A comprehensive analysis of microRNA-124 regulated gene networks and its role in epilepsy.'.

assistant: **Concept**

Evidence is emerging that rapid, profound and persisting changes in gene expression regulation and post-transcriptional regulation underlies the epileptogenic process. The current proposal builds on preliminary data which demonstrates that rapid reduction of a microRNA; miR-124, causes increased expression and activity of NRSF,  a master-regulator of epileptogenesis. The current proposal will build on this and investigate other gene networks regulated by miR-124 in neurons, by developing the first miR-124 KO mouse using CRISPR technology and a miR-124 overexpressing mouse. These transgenic mice will then be profiled at the epigenomic level using ATAC-Seq, the transcriptome level using HITS-CLIP and ribosomal profiling and the proteomic level using mass spec. This will be the first study to examine the pleiotropic role of miR-124 in mature neurons and identify gene networks regulated by this neuronally enriched miRNA. If miR-124 disruption causes aberrant activity of epigenetic modifiers including NRSF then we will test whether miR-124 restitution can restore correct gene expression networks and prevent or modify epileptogenesis in a mouse model of the disorder. Next we will determine whether data obtained in mouse models is translatable to the human form of the condition by obtaining and maintaining resected human epileptic hippocampus live in culture. We will ectopically introduce miR-124 and test the effect of miR-124 restitution on network activity and energetics using live-calcium imaging as well as the epigenomic and transcriptomic effects. Together this proposal represents the most in-depth analysis of miRNA function and will set the standard for future functional analyses of these molecules. Furthermore it has the potential to intervene in disease process and app
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'SARIDAS: Saratoga Integrated Dental Simulation Platform' (SARIDAS).

assistant: **Innovation**

Dental departments are losing clinical faculty to private practice as it is a more lucrative option. The effect of the loss of dental faculty requires dental institutes to find ways to meet the student needs during practicals. Saratoga S.p.A is a company that was established in 1973 that manufactures dental equipment, furniture as well as dental educational tools and systems. Saratoga has developed SARIDAS which is a computerised, dental artificial intelligence-based platform that responds to the challenges faced by dental students and clinical faculty. SARIDAS consists of four components. It contains a smart dental simulator that has a phantom head in which oral diseases are replicated for the student to practice treatment procedures. It also possesses an interactive tool that transmits images, videos and audio between workstations allowing for communication between a student and the instructor. The third component is an augmented reality unit which tracks the handpiece in the mannequin’s oral cavity and provides highly accurate assessment of student’s work. The last component is an artificial intelligence software ‘brain’ that interconnects the above 3 components and also contains a database in which clinical data about different oral conditions and the methods of treatment can be stored for use by the students. The smart brain component provides predictive technology and offers guidance to students on how to treat diseases that they have not yet encountered in the classroom. Our system provides unlimited practice from multiple pre-recorded dental exercises and the database provides students with access to international pathology data. SARIDAS offers instant feedback for correction where students would otherwise only be able to practice when the instructor is availabl
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Changing the course of cognitive decline in normal aging with positive emotions by training brain plasticity'.

assistant: **Concept**

Aging is a primary health concern for all European countries and the entire world. Healthy adults experience memory declines that affect daily functioning, yet their ability to process emotion is well-preserved. The benefit of utilizing older adults spared emotional abilities to help mitigate memory declines has not been previously explored and will have substantial implications for daily life. The current project has two main goals. First, we will employ cutting-edge functional imaging technology to investigate age-related neural interactions between emotion and memory. To this end, electroencephalography (EEG) will record electrical brain activity non-invasively while participants perform an innovative memory task with an emotional component. Second, we will implement an innovative memory training programme to test brain plasticity, with a focus on transferring these benefits to daily life. It will enhance the importance of age-related preserved emotions to improve memory deficits. EEG activity will be recorded before and after training to examine the neural changes as a result of training. Besides the extensive research experience of the applicant in fundamental research of aging, the novel approach will be to conduct this project by synergizing key aspects of fundamental and applied sciences, emphasizing transfer of knowledge and collaboration with industry. There is a clear benefit of the mobility for both the applicant and the host, ensuring high quality results and dissemination. In this regard, the host will ensure the acquisition of new technical, management, tutorial and transferable skills. The applicant will also benefit from a multidisciplinary environment enhancing international collaboration that will surely contribute to diversify her career. Finally, vi