RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Cutting-Edge Anion Exchange Membrane Electrolyzer for Sustainable Green Hydrogen Production: From Advanced Catalyst Synthesis to Innovative Membrane-Electrode Assembly Fabrication' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

H2-IMPACT seeks to transform anion exchange membrane water electrolysis (AEMWE) technology to enable sustainable large-scale green hydrogen production. The project addresses critical challenges, including the need for cost-effective, durable, and platinum group metal (PGM)-free electrocatalysts, as well as the stability of membrane-electrode assemblies (MEA).To overcome these issues, H2-IMPACT implements innovative catalyst synthesis methods that precisely regulate electronic structures, maximize active site density, and enhance ionic conductivity. This includes the creation of high-performance Ni-based catalysts doped with high-valent metals, confined within porous carbon supports for anode and cathode. The project also develops a groundbreaking ionomer-free MEA design with a strip-shaped hydroxyl ion conduction pathway to control local pH and enable in situ/operando analysis under real operating conditions. H2-IMPACT aims to deliver a cost-effective 5-cell AEMWE stack prototype (TRL4), targeting hydrogen production costs below €2.5/kg and a lifespan exceeding 5,000 hours. The project focuses on four core objectives: designing durable PGM-free electrocatalysts, fabricating stable ionomer-free MEA, developing high-performance AEMWE cells, and demonstrating a large-scale prototype integrated with solar energy. The project strategy combines advanced materials science and electrochemical techniques to optimize AEMWE performance.H2-IMPACT will significantly enhance my research profile by providing multidisciplinary training in hybrid catalyst synthesis, operando/in-situ techniques, and scientific communication. It will also expand my professional network in technologies, such as metal-air batteries for bifunctional air electrodes. Additionally, I will contribute my expertis
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Direct Functionalization of Unprotected Aziridines via Boryl Radical-Induced β-Scission' (AZIRIDINE), addressing dissemination and exploitation.

assistant: **Impact**

β-Functionalized amines are privileged motifs in pharmaceuticals, and agrochemicals, yet their synthesis typically requires lengthy & challenging routes. Aziridines represent attractive starting points, but current ring-opening strategies are restricted to pre-activated substrates bearing strong electron-withdrawing groups, which limits their synthetic utility. No general methods exist for the direct functionalization of unprotected or N-alkyl aziridines into β-amines.This project introduces a new approach that harnesses boryl radical chemistry to directly deconstruct aziridines. Coordination of BH₃ to the aziridine will enable generation of aziridine-bound boryl radicals, which undergo selective β-scission to produce β-aminoalkyl radicals. These intermediates will then be intercepted by radical acceptors to deliver a broad range of β-functionalized amines in a single step.The methodology will progress in two stages: (1) development of photocatalytic ring-opening processes and divergent radical functionalizations using many SOMOphiles, and (2) integration with nickel catalysis to achieve cross-couplings with aryl, alkyl, and acyl partners. Mechanistic elucidation by spectroscopy, actinometry, and photolysis will underpin the design and guide reaction development.This strategy establishes the first general platform for aziridine ring-opening and functionalization without pre-activation, opening a new retrosynthetic paradigm for the synthesis of β-amines. Beyond methodological innovation, it provides a blueprint for the late-stage diversification of bioactive scaffolds and creates powerful shortcuts to molecules of direct medicinal relevance.Completion of this innovative and ambitious project at RWTH Aachen University will be supported by comprehensive training, knowledge
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Qualification and Diagnosis of Carbon and Glass Fibre-Reinforced Composites with Non-Destructive Measurement Technologies' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

Today, fibre-reinforced composites (CRP/GRP)  can be found in high tech applications like in aerospace and energy industry. The production of these materials is expensive and the quality control is often manually conducted. As the processes of quality control and even the way how to analyse and characterize damage and defects within fibre-reinforced composites are not standardized yet, parts consisting of these materials are replaced instead of being repaired, often without being sure, whether the function of the part is negatively affected or not. It can be easily imagined, that high costs occur by this approach.In the future fibre-reinforced composites will be increasingly used in every industrial sector, in which material characteristics like light weight in combination with high resistance is required. Especially automotive industry is now focussing on these new materials, looking for innovative application areas e.g. trim parts without additional finishing. For this purpose manufacturing processes and material costs have to be developed in a comparable range of today’s costs.The proposed project will examine the possible ways for an adequate quality assurance for CFP- or GRP-components. To receive calculable quality, measurement methods and data processing procedures are necessary. Considering different aspects of CRP/GRP-products it is obvious, that only non-destructive technologies like 3D-computer tomography, thermography and ultrasonic scanning in correlation with intelligent software solutions will lead to significant and evaluable results.The overall aim is to achieve a comparable and measurable quality standard for CRP/GRP products. This will prepare applied CRP/GRP products to enter large-scale markets and new industries. The project results and the gathere
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Novel peptidomimetics for inhibition of MDM2 in glioblastoma' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

Mouse double minute 2 homolog (MDM2) is a primary antagonist of p53 tumour suppressor, and MDM2 inhibition represents an attractive way to restore p53 function. Peptidomimetics which are based on p53 sequence-derived structure, are one of the most promising tools for mimicking MDM2/p53 interaction. Varying structure of peptidomimetics gives opportunity to measure effect of fine structure changes on inhibition process. Linking peptidomimetics with fluorophores represents an attractive way to spatially track inhibition process. In this project we aim to synthesize novel fluorophore-peptidomimetic probes (FPPs) for MDM2 inhibition. Fluorophores triarylboranes will be covalently linked to peptidomimetics and introduced into patient-derived glioma stem cells. In the first part of the project we will detect effect of MDM2 inhibition on major histocompatibility (MHC-I) peptides presentation at cell surface. Further, we aim to investigate immunogenic response of CD4+ T cells on MHC-I peptides presentation. In the second part of the project we will investigate effect of proteasomal inhibition on MDM2 and p53 degradation, and their role in composition of MHC-I peptides. Immune response on presentation of novel MHC-I repertoire at the cell surface will be tested with co-cultivation with CD4+ T cells. By focusing on these particular pathways, GlioLight intends to hinder the processes that enable GBM cells to grow and escape standard treatments. Ultimately, this effort paves the way for advancements in personalized medicine.


**Keywords:** MDM2, p53, fluorophores, peptidomimetics, cancer, inhibition, MHC-I, mass spectrometry
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Grosser wellenkanal (gwk) - large wave channel' (1998-2002).

assistant: **Innovation**

Description:The research facility LARGE WAVE CHANNEL (GWK) of the Coastal Research Centre (FZK) is one of the largest facility of its kind worldwide (309 m long, 5 m wide, 7 m deep). It is used for large-scale experiments on research topics related to Coastal and Ocean Engineering. In the past research has been performed on coastal structures (dikes, breakwaters, revetments), offshore structures (cylinders, pipes) and wave-induced sediment transport (dune erosion, shoreline protection). Wave heights up to 2.0 m can be generated with a maximum water depth of 5 m. State-of-the-art wave generation and absorption control are available including irregular and freak wave generation. This also includes state-of-the-art measuring and recording instruments, data acquisition, processing and analysis systems. The EC supported Transnational Access (in action of the Improving Human Potential Programme) has started on 1st. of March 2000 and has a duration of 3 years. The offered total amount of access for the full period is 30 experimental weeks and the number of individual users who will benefit from this access is estimated to 36.Application:Interested researchers are invited to submit a letter of interest or an one-page proposal to the Coastal Research Centre (FZK). After reception the potential users will receive further detailed information in order to discuss details of the proposed research project. A feasibility check with further discussions should lead to a final proposal, including the model-set-up, measuring techniques, test procedures and access time. The final proposals will be peer-reviewed once a year by an User Selection Panel which will be composed of independent external experts and facility experts. This Panel will recommend a shortlist to be submitted to the EC f
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Minimal entropy and topological rigidity of manifolds admitting nontrivial maps onto locally symmetric spaces' to be submitted under Fourth Framework.

assistant: **Abstract**

RESEARCH OBJECTIVES AND CONTENT The objective of the project is to investigate certain problems of topological and differential rigidity related to the Minimal Entropy Problem, for manifolds admitting nontrivial maps onto locally symmetric spaces of negative curvature. I am going especially to treat the case of negatively curved manifolds and that of manifolds with splittable fundamental group. With this aim, I intend to study the notion of growth tightness in Riemannian Geometry, which seems to play a crucial role in such problems. I also mean to analyze the relationship between the pinching of the volume-entropy functional (possibly under additional assumptions on the geometric invariants of the metrics realizing the pinching) and the Gromov-Hausdorff convergence. TRAINING CONTENT (OBJECTIVE, BENEFIT AND EXPECTED IMPACT) The training content concerns the study of the most recent techniques developed to deal with these topics, namely: - approximation of isometries by means of immersions in spaces of measures, following Besson-Courtois-Gallot; - Gromov hyperbolic groups; - methods a la Cheeger-Colding for manifolds with Ricci curvature bounded from below (Gromov-Hausdorff distance, Bochner formulas, approximation of distance functions with harmonic functions). The combination of the above mentioned techniques should lead to a new approach to the investigation of pinching problems and of rigidity of negatively curved manifolds. Links with industry / industrial relevance (22)
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Universal PlugPlay OEE Data Capture Equipment to improve the efficiency of industrial processes' (2014-2020).

assistant: **Concept**

The production lines of industrial companies are very heterogeneous, with machines from various brands, models, generations and technologies. Due to this heterogeneity, the bespoke solutions for data capture are very expensive and are difficult to implement. For this reason, the penetration of data capture solutions in companies is very low.Sistemas OEE de Productividad Industrial, S.L.L. has developed some innovative universal equipment for automated Real-Time Data Capture on production lines, called Smooth Readers. They are a true breakthrough due to its universal system of connection and for its ability to achieve a connection with the machines in a very brief time, practically making it a Plug and Play. It is a range of standard products that are easily configurable in situ by the client (DIY), or remotely via the web, which cover the requirements for data capture/collection of almost the totality of the machines on the market. The main innovations of the Smooth Reader system include the following:- Plug and Play. Installation in production line in less than one hour.- Breakthrough technology at cost level.- Universal product, connectable to any production process. - Great connectivity that allows the capturing of numerous parameters. - Include a portable kit to perform pilot tests.- Modular and scalable system.The innovation is based on a self-developed algorithm, the result of three years of research, that is used to program the Smooth Reader, and which allows it to communicate with any type of machine.Sistemas OEE makes the data capture systems for the improvement of productivity accessible for European SMEs, so these SMEs can incorporate progressively advanced production technologies.The objective of this phase 1 is to complete a feasibility study to find out th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Innovative polymers from tomato cutin esters monomers'.

assistant: **Objectives**

The production of cutin-based polymers is currently made from acid monomers that result in conventional plastics. These cutin-based plastics do not have the 3D structure of the natural cutin, limiting its application. POLYMATOS project aims to develop an isolation and fractionation integrated high-pressure process to obtain cutin esters monomers from tomato pomace (TP) to be applied as building blocks of innovative biopolymers. The present proposal relates with a novel approach to the production of polyesters by addressing a key challenge in the current biopolymer research: the maintenance of the flexible 3D polymeric structure characteristic of cutin in a cutin-like polyester using ester monomers instead of acid monomers. This approach can efficiently increase hydrophilicity and degradability plus modulate the mechanical, chemical, and biological properties of polyesters. The research will focus on evaluating the process conditions that would achieve cutin yields and highly functionalised building blocks in continuous microreactors. POLYMATOS has a strong multidisciplinary character since it links together biology, biochemistry, chemical engineering, and material science to expand the application of TP to the production of an innovative polyester. The proposed process will be a fundamental contribution to generating an additional revenue stream and reducing residues production in tomato processing. Due to the abundance of cutin, the findings can be extended to other production activities, benefiting the food industry and society. POLYMATOS will allow me to develop my leadership skills through innovation. The project will be carried out by the experienced researcher Dr. Aguiar at the Bioeconomy Research Institute, Universidad de Valladolid, under the mentorship of Prof.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Selectively activated INFOrmation technology by hybrid Organic Interfaces'.

assistant: **Objectives**

SINFONIA - “Selectively activated INFOrmation technology by hybrid Organic Interfaces” – is an interdisciplinary research project that envisions a technology allowing to store and transport information on the nanometer length scale and at operational frequencies in the THz regime. Such a technology will be realized through an optical manipulation of hybrid molecular/antiferromagnetic interfaces, which will enable a selective activation of information emitters and detectors. Such a selectivity will be ensured by the local nature of the hybridized electronic states that develops at the interface between an antiferromagnet (AF) and a molecular system. The main objective of SINFONIA is to exploit the hybridized states created at such interfaces to couple an external optical stimulus to the propagation of magnetic perturbations (namely spin waves) in the AF layer. This way, SINFONIA proposes a completely new approach to information technology, based on hybrid organic/inorganic low-dimensional systems. Among the breakthroughs offered by such a change of paradigm, there are: low power consumption (no electrical currents), high-frequency responses (ensured by AF materials), tunability (ensured by molecular materials), scalability and miniaturization, on account of the intrinsic low-dimensionality of our interface-based approach. SINFONIA also envisions the long-term perspective of realizing fully organic devices, thurough the development of organic AF films. The proof-of-concept of the proposed technological approach will be sought in the development of magnonics prototypical devices, such as logic gates. Magnonics is widely recognised as one of the most promising technological approaches to go beyond CMOS technology, which represents the state-of-the-art in information and com
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'MicroTechnologies for Re-launching European Machine Manufacturing SMEs' demonstrating excellence, impact and implementation quality for a Sixth Framework call.

assistant: **Abstract**

The need to produce microcomponents in a mass scale introduces new production requirements for the machine and equipment manufacturers in terms of making available appropriated, cost-effective and reliable equipment for producing those microcomponents. I t is a fact that most of the European Machine Tool SME companies and component manufacturers are getting in the doldrums, so they will not be competent in offering such high-tech solutions in a competitive way when the micromanufacturing at mass scale be comes a reality. To deal effectively with such a problem in order to achieve the desired competitiveness, European SMEs in the machine tool manufacturing and tooling production sectors must: (a) Acquire knowledge about micromanufacturing technologies in order to be able to produce complete solutions (machine + process) for microcomponents manufacturing (b) Create a collaborative scenario in the field of microcomponents manufacturing in which SMEs can access the necessary multidisciplinary knowledge a nd skills to lead the market of micro manufacturing equipment. The LAUNCH-MICRO IP proposal will intend to solve the above described situation and in doing so will contribute to increase the competitiveness and sustainability of EU SME Machine Tool and c omponents manufacturers in issues related with micromanufacturing. Main objectives of LAUNCH-MICRO proposal will be: To provide EU Machine Tool SMEs with the technical knowledge and methodologies for the construction of equipment for micromanufacturing.  To provide EU SMEs with leading edge knowledge on micromanufacturing that will allow them to compete at a global manufacturing level. To convert this sector in a growing and dynamic technology-based one thanks to an effective use of ICT technologies. To use the existing kno