RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Human-Centred Machine Learning: Lighter, Clearer, Safer' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

The rapid development and adoption of Artificial Intelligence (AI) and Machine Learning (ML) technologies have brought significant opportunities and challenges. While AI has the potential to revolutionise industries and improve lives, there are growing concerns related to privacy, security, fairness, transparency and the environmental footprint. The Olympics motto ""Faster, Higher, Stronger"" also applies to recent impressive AI advancements, but now is the time to update it to ""Lighter, Clearer, Safer"". We propose ACHILLES to build an efficient, compliant, and trustworthy AI ecosystem. At its core is an iterative development cycle inspired by clinical trials encompassing four modules. It begins with human-centric methodologies, followed by data-centric operations, model-centric strategies, and deployment-centric optimisations. It returns to human-centric approaches, focusing on explainability and model monitoring. This iterative cycle aims to enhance AI systems' performance, robustness and efficiency while ensuring they comply with the legal requirements and highest ethical standards.Another innovation is the development of an ML-driven Integrated Development Environment (IDE). The ACHILLES IDE will facilitate seamless integration between the iterative cycle's modules, enabling users to develop efficient, compliant, and trustworthy AI solutions more effectively and responsibly. The project aims to significantly impact European AI development, aligning with the region's guidelines and values. Through innovative techniques and methodologies based on the collaboration of a multidisciplinary team of 16 partners from 10 countries, ACHILLES will foster a strong AI ecosystem that respects privacy, security, and ethical principles across various sectors. By validating the re
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Sewerage inspection using radar-technology' in the context of a Fifth Framework call.

assistant: **Objectives**

Our aim is to develop a measuring system which uses georama technology allowing simple non-destructive examination of canalisation systems (waste water channels) and checking the surrounding soil in which they are embedded for cavities. During the measurement the measuring data are to be displayed directly on a display and stored for later data backup on magnetic tape. We need to develop a software which enables the user of such a measuring system to view an evaluation directly on the display and use it to assess the state of a canalisation system. This measuring system has to meet the following requirements: Ascertaining the wall thickness of the pipe for determination its current bearing capacity. Recognition of the bedding state of the pipe and the compactness of the surrounding soil. Detection of leakages. Detection of cavities. Assessment of the pipe covering regarding collapsing of the surface.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Tubular Supramolecular Polymers: A new class of therapeutic polymers' in the context of a Horizon 2020 call.

assistant: **Objectives**

This research programme will establish a new class of materials and develop them into functional devices for biomedical applications. We will design tubular supramolecular polymers, supramolecular polymer brushes (SPBs), based on the self-assembly of cyclic peptide – polymer conjugates.  The synergy between the cyclic peptide, which directs the formation of the SPBs and the polymer conjugate, which provides functionality, will open the route to a wealth of new functional structures.  We will build on our initial work and expand our research to generate new synthetic routes for the ligation of polymers to peptides, develop new protocols for the characterisation of the materials, and establish the mechanism of supramolecular polymerisation. This research programme will open new horizons in the fundamental understanding and production of supramolecular polymers. In particular, beyond the generation of new materials, the functionality of these systems may allow the development of supramolecular living polymers, a long-standing goal in polymer chemistry that is still elusive. The functionality and versatility of the SPBs obtained in this work open the route to a wealth of applications, and we will focus on one specific target: the fabrication of drug delivery vectors. We will exploit the unique combination of features presented by this new class of polymer therapeutics, such as multiple attachment points for one or more drug(s) / targeting ligands / markers, the ability to self-disassemble into smaller and easy-to-excrete components, and an elongated shape that enables diffusion and interaction with cells more efficiently than traditional globular delivery systems. We will study the pharmacology properties of the SPBs, including their stability, toxicity, mode of cell penetr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'The European Robot Initiative for Strengthening the Competitiveness of SMEs in Manufacturing' (SMEROBOT) targeting Sixth Framework.

assistant: **Abstract**

More than 219000 manufacturing SMEs in the EU are a crucial factor in Europe's competitiveness, wealth creation, quality of life and employment. Existing technologies have been developed for capital-intensive large-volume manufacturing, resulting in costly and complex systems which typically cannot be used in an SME context. Therefore, manufacturing SMEs are today caught in an automation trap: they must either opt for current and inappropriate automation solutions or compete on the basis of lowest wages.The SMErobot initiative offers an escape out of the automation trap through:- Technology development of SME robot systems adaptable to varying degrees of automation- New business models creating options for financing and operating robot automation- Empowering the supply chain of robot automationThe following radical innovations are the prime deliverables of the technical work packages:1. The robot capable of understanding human-like instructions2. The safe and productive human-aware space-sharing robot3. The three-day-deployable integrated robot systemThe unique composition of the consortium, including six major European robot manufacturers, leading research institutes and universities enables standardization activities for maximum European impact on worldwide standards. SMEs and society benefit from the combined integration of knowledge from component manufacturers to end users, from multidisciplinary activities from mechatronics to business/financing models and from fundamental technical research to SME applications. Management includes dedicated support for SME integration. SMErobot will lead to affordable, dependable and versatile robots with significantly reduced robot setup, changeover and instruction times, which can be used for side-by-side assistance of workers
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'How Effective are Illiberal Strategies of Citizen Manipulation?' to be submitted under Horizon Europe.

assistant: **Abstract**

The widespread popular support for illiberal leaders seeking to subvert democracy is one of the more puzzling and concerning developments in the 21st century. From Putin through Orbán to Erdogan, illiberal leaders invest large resources into propaganda, organize grandiose displays of support, and promote hostile rumours about their enemies. But do such attempts at manipulation shape citizens' support and acceptance of the illiberal leader? Prior research yields conflicting expectations. On the one hand, research in psychology and political behaviour identified a plethora of cognitive biases, which undermine citizens' ability to punish leaders for their mistakes or wrongdoings. On the other hand, recent evidence shows that people are difficult to persuade, making it unlikely that propaganda could change the minds of citizens who are critical of an illiberal leader. To adjudicate between these accounts, this project will a) develop a novel framework for studying the effects of illiberal manipulation strategies and will examine the effects of multiple manipulation attempts, such as b) hostile rhetoric, c) political misinformation campaigns, and d) populist appeals to fairness intuitions. The project builds on an interdisciplinary framework bridging insights from comparative politics and psychological science, and will employ a diverse set of methodological tools from multiple survey experiments (vignette, conjoint, and cultural transmission designs) as well as quantitative text analysis. Original comparative survey data from Hungary, the US, and Denmark will be used to compare citizens' susceptibility to manipulation under different political environments. The project contributes to the European Commission's priority of ""a new push for European democracy"" by informing pr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Tribo-Reactor for fluorine circularity by urban mining'.

assistant: **Concept**

TriFluorium largely expands current circular economy capabilities for highly stable organofluoride waste (PFAS, including fluoropolymers) and provides safe, sustainable and efficient regeneration of fluorine into safe, stable inorganic fluorides as industrial resource, such as fluorspar. Fluoropolymers are indispensable for many critical (e.g., semiconductors) and green (e.g, hydrogen production, fuel cells, EVs) applications and their disposal options are very limited. Needed fluorspar resource is listed as EUs critical raw material and is acquired outside of the EU with recycling rate at 1% due to the lack of proper technologies. TriFluorium wants to achieve proof of the tribolysis recycling principle for organofluorides (TRL 3) irrespective of particular chemical structure, molecular weight, or liquid/solid form under properly designed controllable tribocontact site, which promotes chemical reactions initiated by mechanical stimuli. Tribolysis shall within one processing step generate local dense-energy spots to initiate decomposition of very stable organofluorides, including the perfluorinated ones, and to activate safe reactants, such as alkaline earth metal (Group II) salts or oxides to efficiently convert organofluorides into safe, stable inorganic products (mineralization).TriFluorium will also develop a dedicated Tribo-Reactor for laboratory scale validation of tribolysis F-recycling (TRL 4) for process scaling and enhancement of tribolysis technology development towards industrial application. The locally initiated reactions with benign reactants have inherently safe operational and energy-efficiency features. Supporting toxicological and LCA assessments will be carried out to comprehensively evaluate tribolysis recycling process and Tribo-Reactor performance
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Innovative Strategies towards Halogenated Organic Molecules: From Reaction Design to Application in Drug Synthesis' (HALODRUGSYN).

assistant: **Concept**

Halogenated arenes and heteroarenes have become essential structural motifs of the pharmaceutical industry to create novel drugs against bacterial infections and cancer, and constitute highly valuable functional units in chemistry. Current methods for the installation of carbon-halogen bonds lack efficiency, selectivity, and practicability within the complex molecular setting of drug development processes. These restrictions prevent many potential drugs from being synthesized in a time- and cost-efficient manner.In this project, I aim to address these challenges by engineering a highly elaborated synthetic toolbox that is equipped with novel transformations of unprecedented efficiency, selectivity and practicability. I will apply these transformations to the construction of novel antibiotics against resistant strains and more efficient chemotherapeutics to combat cancer.The first objective is to establish innovative transformations that enable for the first time an efficient access to halogenated arenes. I will accomplish this goal by developing novel ring-expansion reactions and apply them to the first synthesis of the antibiotic salimabromide in order to address the acute problem of antibiotic resistance. Within the second part of this project, I will extend this unique synthetic platform to heteroarenes and establish a groundbreaking method based on carbon-fluorine bond activation. This will represent the first broadly applicable strategy to produce novel fluorinated heteroarene based anti-cancer drugs with unparalleled precision, efficiency and selectivity. Taken together, the realization of these strategies, all of which are unprecedented, provides for the first time a solution for the limitations associated with current methods. With my expertise in synthetic chem
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Componentware for autonomic, situation-aware communications and dynamically adaptable services' demonstrating excellence, impact and implementation quality for a Sixth Framework call.

assistant: **Abstract**

As European citizens, we are witnessing an age of computing ubiquity where our work and home environments are enveloped by computing resources. This comes at a cost, which is the significant problem of configuration and complexity of these resources. If computing power is to serve us, and the converse is to be denied, then these resources and their rich panoply of services must be able to carry out their increasingly complex functions without significant intrusion into our lives. CASCADAS is a three-year integrated project driven by a clear research vision, which is to define a new generation of composite, highly-distributed, pervasive services, with underlying technology, that addresses these configuration and complexity problems.Our central objective with CASCADAS is to identify, develop, and evaluate a general-purpose abstraction for autonomic communication services, in which components autonomously achieve self-organisation and self-adaptation towards the provision of adaptive and situated communication-intensive services. We will achieve this objective by developing a common abstraction, called an ACE (Autonomic Communication Element), which represents the cornerstone of our component model. We will also use four key, underpinning scientific principles in CASCADAS, which are situation awareness, semantic self-organisation, self-similarity, and autonomic componentware to help guide the project.The ACE concept, together with the use of the four principles ensures that CASCADAS overlaps strongly with the goals of the Situated and Autonomic Communications" call. CASCADAS is highly relevant to the two main objectives of this call, in that we precisely "define a self-organising communication network concept", and we also "study how strategic needs impact on future commun
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Towards Understanding the Structure and Dynamics of Receptor Proteins' under Seventh Framework.

assistant: **Concept**

Upon binding an agonist, the seven transmembrane (TM) helical bundle of a G-protein coupled receptor (GPCR) undergoes conformational changes that catalyze nucleotide exchange within bound G proteins. In rhodopsin, the agonist arises from light-induced isomerization of the retinal ligand, but an active conformation (Ops*) can also be adopted by the opsin apoprotein. We recently solved the structure of Ops* in complex with a peptide from the C-terminal ±-5 helix of the G protein. Considering this structure and previous work, we postulate a mechanism by which the 40 Å gap between the retinal and the nucleotide binding site is bridged. First, TM5 and TM6 engage in new interactions to form a mitt-like structure into which the G-protein ±-5 helix can bind. Second, the bound ±-5 helix switches into a new position, thereby acting as a transmission rod to the nucleotide binding site. In the proposed project, we will test this mechanism and explore the underlying protein dynamics by: - determining the structure of the receptor in complex with longer peptides, and if possible, with the G holoprotein, - measuring conformational changes on the timescale of receptor activation (ms) and expand computational modelling of the respective transitory complexes, - determining the underlying backbone dynamics and fluctuations on the ps-ns time scale by experimentation and molecular dynamics. Some of the necessary methodologies are available, while others must be developed or made available through collaborations. Rhodopsin is the ideal model system for studying signal transduction mechanisms. Our novel multi-prong approach, while risky, will enormously improve our understanding of GPCR signalling mechanisms. The insights gained will be significant for receptor-directed drug development.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Determination of top couplings in associated top pair events using ATLAS data'.

assistant: **Objectives**

The discovery of a new particle, compatible with the Higgs boson, at the Large Hadron Collider, marked a major triumph of the Standard Model of particle physics. However, many fundamental questions remain and direct or indirect evidence of new physics can be probed with the large number of proton-proton collision data, collected in 2011 and 2012 at 7 and 8 TeV centre-of-mass energy.With this proposal we plan to exploit the large sample of top-quark pair events that is already recorded, and the sample that will be collected from 2015 onwards, at the ultimate energy of 14 TeV. In particular we plan to study the coupling of top quarks to neutral bosons, by measuring the production of associated tt̄γ, tt̄Z and tt̄H. Anomalous electromagnetic or weak couplings could be uncovered by studying kinematic properties of the resulting photon or Z-boson, once the signal is established. By studying the tt̄H production in detail the mechanism of Yukawa coupling of the Higgs boson to fermions will be tested, possibly providing important confidence in the characterisation of the new boson.In all measurements we plan to include the tt̄ dilepton channel, that, despite the smaller branching fraction has typically superior signal-to-noise ratios. An essential part of the programme will be the calibration of the b-tagging algorithms, where we plan to use tt̄ events. For associated Higgs production we will explore the decays H→ bb̄ and H→ γγ.