RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Analysing Learning in Regulatory Governance' (ALREG).

assistant: **Concept**

This four-year interdisciplinary project addresses the question  what has been learned through the use of better regulation ? Better regulation is a flagship policy on the Lisbon agenda for growth and jobs. Its aims are to provide new governance architectures for law-making, to increase the competitiveness of the regulatory environment, and to secure wide social legitimacy for multi-level systems of rules. Whilst most of the research has looked at how better regulation is changing, this project will produce findings on what has changed because of better regulation. Theoretically, the project will use (and significantly improve on) theories of policy learning. Empirically, it will cover Denmark, Italy, the Netherlands, Poland, the UK and the EU   including multi-level analysis and analysis by sector of regulation. Methodologically, the project will draw on comparative analysis of types of learning, experiments with regulatory policy-makers in six countries and the European Commission, large-n analysis of impact assessments, backward-mapping of legislation (to appraise the role played by better regulation in the formulation or laws in the UK and the EU), meta-analysis of case-studies and co-production of knowledge with better regulation officers. Dissemination will target both stakeholders (i.e., policy officers, civil society organizations, and business federations) and academic conferences in political science, law, and risk analysis, with a major research monograph to be completed in year 4 and a final interdisciplinary conference.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Substrate-induced phases of discotic liquid crystals' in the context of a Seventh Framework call.

assistant: **Objectives**

The structure of ordinary liquids is altered near a solid surface. The symmetry breaking leads to positional and orientational ordering of molecules. The ordering effect extends generally up to a few molecular dimensions only. A solid interface also plays a well-documented role on the nucleation and growth of crystals. But probably the richer physical situations are observed in the case of liquid crystals, notably anchoring and orientational wetting effects. Liquid crystals are ideal systems to study surface effects for many reasons. First, their fluid character allows reaching thermodynamic equilibrium easily. Second, surface-induced orientational and positional ordering effects can be selectively studied. Third, liquid crystals display several phase transitions around which peculiar phenomena occur. Fourth, liquid crystalline phases are highly symmetrical and allow an easy structural characterization by powder X-ray diffraction. Fifth, liquid crystalline compounds are generally more soluble and easier to process into thin films than crystals. In case of discotic liquid crystals, unusual and interesting phases appear in the vicinity of solid substrates. Such “thin film” phase differs from those for crystalline compounds, where surface induced polymorphism occurs. Such thin film phases in crystals are thermodynamically unstable since a perturbation of the system leads to its transformation into a more stable polymorph that exists also in bulk. The substrate-induced phases observed in discotic liquid crystals are more ordered than the bulk ones and exhibit a three-dimensional order whereas the bulk ones are liquid crystalline and have a two-dimensional order. This project aims to gain a fundamental understanding of the physical and chemical parameters that governs the fo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Chiral semiconductor nanophotonics for ultraresolved molecular sensing'.

assistant: **Innovation**

Chirality plays a pivotal role in chemistry and medicine because most biological molecules have either right- or left-handed conformations. Circular dichroism can distinguish the chirality of matter thanks to a small difference in absorption of light with opposite circular polarizations. However, it is severely limited by low sensitivity and low spatial resolution due to weak chiral light-matter interaction. As a result, using light, we cannot resolve the chirality of individual nanoscale objects for critical applications such as detecting protein aggregates responsible for a variety of diseases.CHANSON pushes the limits of optically resolvable chirality through new concepts in semiconductor nanophotonics. We tailor semiconductor nanostructures to specifically boost chiral fluorescence thanks to the interplay of photons, charges, and spins. Using novel contrast mechanisms, we increase both fluorescence intensity and polarization to remove the barriers that hinder circular dichroism. The project combines two routes for ultrasensitive and super-resolved molecular detection: 1) Nanophotonic sensors based on semiconductor nanoantennas; 2) Excitonic sensors based on atomically thin semiconductors. The ambitious target is to map with nanoscale spatial resolution the lowest possible molecular concentrations down to a single chiral molecule. To tackle this major scientific challenge, I propose the concept of a metasurface canvas consisting of arrays of semiconductor nanostructures. By providing a platform for fluorescence-based sensing of both light-emitting and non-emitting analytes, the results could revolutionize the screening of pharmaceuticals for neurodegenerative diseases, amongst others.


**Keywords:** Nanophotonics; Optical chirality; Circular Dichroism; Fluorescence;
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'SMASH, SMArt SHaring device for mobility', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

SMASH is a Smart Sharing Device aiming to improve the access and the fruition of innovative urban mobility, through the combined use of satellite tracking technology and wireless transmission, embedded in a single miniaturized device.The proposed device, developed by greenspider and available in prototype,  integrates in a single ultra-low-power electronic circuit a GNSS receiver, Near Field Communication (NFC),Bluetooth Low Energy (BLE), and GPRS module for connection to the cloud. The supported NFC is compatible with the standard nowadays adopted by major Smartphones manufactures and mobile operators, and it's considered a disruptive technology to enable secure authentication, mobile access and payment via Smartphone. With this characteristic SMASH permits a direct NFC interaction with end-user smartphone, and correlate positioning data retrieved from different positioning device.SMASH enables access to innovative mobility schemes, thanks to its embedded GNSS and proximity interaction between the user's Applet and the device. The device can be integrated into vehicles and infrastuctures, like parking or charging stations, or in general in any resource in a sharing scheme, allowing easy NFC controls and data sharing. Thanks to the NFC connection,the data related to the user's access request and  to the available resources, with the relative positions, are exchanged in a safe and reliabl way, and shared in the cloud, enabling innovative mobility service and advanced fleet management. The units of fleet management in Europe has risen from 1.5 million units in 2009 to 4 million in 2014, and are expected to grow further in the next years. The penetration of NFC across all handset is planned to reach approximately 32% by 2017, with more than 1 Billion smartphone with NFC su
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Prevention of Small Diameter Prosthetic Vascular Graft Failure by Ex-Vivo Gene Therapy with Infected Fibroblasts and/or Biologically Active Peptides', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

The objective of this proposal is to identify new strategies to improve the patency rate of small diameter (< 4mm) prosthetic vascular grafts (SDPVG) following arterial reconstruction. More specifically, in this proposal it is planned to examine whether new ex-vivo gene therapy strategies with replication deficient adenovirus vectors and/or the use of biologically active peptides (BAPs) can reduce graft failure rate by achieving the following effects: a) reduction of SDPVG surface thrombogenicity, b) inhibition of SMCs proliferation on the luminal surface of the graft, c) inhibition of SMCs and fibroblasts migration from the surrounding tissues into the mesh of the graft.We plan to use 4mm internal diameter knitted Dacron grafts processed as follows:1) graft coating with fibroblasts infected with Ad-vector carrying the cDNA for Tissue Inhibitor of Metalloproteinase 1 (TIMP-1) to prevent SMC migration into the graft.2) graft coating with fibroblasts infected with Ad-vector carrying the cDNA for Tissue Inhibitor of Metalloproteinase 2 (TIMP-2) to prevent SMC migration into the graft.3) graft coating with fibroblasts infected with Ad-vector carrying the cDNA for Insulin-like Growth Factor type 1 soluble receptor (IGF- 1 Rsol) to prevent SMC proliferation into the graft.4) graft coating with fibroblasts infected with Ad-vector carrying the cDNA for Tissue Plasminogen Activator (t-PA) to induce local fibrinolysis.5) graft coating with a BAP antagonist to Platelet integrin Glycoprotein IIb/IIIa receptor:6) graft coating with a BAP from the RGD-family peptides to prevent platelet aggregation to the graft.7) graft coating with a BAP related to Collagenase IV to prevent SMC migration8) graft coating with a BAP antagonist to basic Fibroblast Growth Factor (bFGF) to prevent SMC pr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'CONSOLIDATING THE EXPERTISE OF NECMETTIN ERBAKAN UNIVERSITY TOWARDS THE DEVELOPMENT OF BIOFIBERS FOR WOUND HEALING AND TISSUE REGENERATION' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

Biomaterials have gained much interest as a very important category of materials because of their wide application in medicine and benefit to patient such as increased longevity and improved quality of life. There is clear evidence of a stable increase of the biomaterials market for the next fifteen years. European Biomaterials Market represents a market of 7 € billion and the global Biomaterials market is five times the European market. Biomaterials sector has not yet been in a good position among the high-value chains in Turkey. Turkey imports biomedical devices, instruments and materials, especially Advanced Therapy and Medicinal Products (ATMPs) about 85%. In Turkey, few R&D activities and limited coordination of academy-industry are the main barriers to develop competitive biomaterial products and high value research in biomaterials field in Turkey.  Necmettin Erbakan University (NEU) is a young University in Konya-Turkey with well-equipped Faculty of Medicine, Faculty of Dentistry, Institute of Science and the dedicated research center, Science and Technology Research and Application Centre, brings together the scientists researching on medicine, material, energy, biomaterial sciences and focusing on creative answers to today's scientific challenges. NEU  has weakness on developing functional biofibers for medicinal applications, specifically to be applied in wound healing and tissue regeneration.  The proposal REGENEU aims to meet the requirements of the HORIZON-WIDERA-2021-ACCESS-03-01: Twinning Call. The main focus of this project is to increase the scientific capabilities and excellence of NEU in the field of biofiber research and development for translational application. This target is supported by European partners Fraunhofer (Germany), UKW (Germany), TCD (
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'THE ROLE OF THE MTOR SIGNALING PATHWAY IN NEUROGENESIS AND ITS IMPLICATIONS FOR THE REGULATION OF ENERGY BALANCE' under Seventh Framework.

assistant: **Concept**

The major interest of my research activity is to understand the pathophysiological mechanisms leading to the development of obesity, particularly focusing on the role of the central nervous system (CNS) in this context. The CNS is the critical organ for the coordination of intracellular metabolic processes that are essential to guarantee energy homeostasis at the organism level. Thus, centering my studies on the atypical kinase mammalian Target Of Rapamycin (mTOR), I recently demonstrated that this evolutionarily conserved fuel sensing pathway integrates sensory inputs from nutrients and hormones within the hypothalamus, in order to modulate food intake and body weight. The ciliary neurotrophic factor (CNTF) is a cytokine whose central administration reduces body weight even in leptin-resistant states, including diet-induced obesity, and causes a weight loss that is maintained after therapy discontinuation. The explanation for this long-term effect of CNTF on energy balance likely resides in its newly described ability to induce neurogenesis within the adult murine hypothalamus. Cellular development and differentiation are tightly coordinated with nutritional status; and induction of mitogenic signaling and neuronal differentiation is known to involve modulation of the mTOR signaling. Thus, I propose that the CNTF effects on neurogenesis and energy balance require the activation of the hypothalamic mTOR signaling pathway. To investigate this hypothesis, I will use a multidisciplinary approach, including the use of genetically modified mice, specific behavioral paradigms and molecular strategies. These studies will clarify the role of cellular fuel sensing mechanisms in the regulation of energy balance and possibly highlight the function of processes, such as neurogenesi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Empire of solidarities: a connected history of private charity across a decentred Romanov Empire, 1855–1914' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

By the late nineteenth century, the Romanov Empire stretched half-way across the globe, turning inhabitants of the territory stretching from todays Tallinn to Vladivostok into subjects of one and the same empire. Yet, we know little about whether the population felt any impulse to help one another in times of need. Under what circumstances did people feel compassion towards distant others and how far-ranging did their sympathies extend? What did these solidarities mean, how were they enacted and expressed through ideas, emotions, and lived experiences? If solidarities could reach across such a multiconfessionally and multiethnically heterogenous empire, how does the Romanov experience enrich our understanding of empire and solidarity as seemingly irreconcilable notions? EMPSOLID applies an unconventional lens to answer these questions. It pioneers a new history of affective practices that, for the first time, focuses on private charity as a method to make solidarities visible and allow us to study them in action. The projects objectives are to: 1) trace the conceptual history of solidarity in the empire; 2) gather and analyse examples of grassroots private charitable initiatives (benevolent and charitable associations, fundraising campaigns, and private donations) across four regionally distinct Romanov imperial border regions (Baltic provinces, Southwestern provinces, South Caucasus, Turkestan) from 1855-1914 on behalf of beneficiaries outside of the givers vicinities; and 3) digitally map flows and networks of donations to generate insights into larger trends and spatial patterns in charitable practices. The projects ambitious, decentring perspective aspires to envision a long-overdue new spatial history of the Romanov Empire in the long nineteenth century founded on
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Novel device to study pulp suspensions behaviour in order to move towards zero energy losses in papermaking' will create measurable scientific, societal and economic impact aligned with Sixth Framework.

assistant: **Impact**

Pulp suspensions are different from other solid-liquid systems because of the unique interactions between the different components of the fiber furnish: fibers, fines, fillers, additives, DCM, etc. Fiber-fiber interactions, fiber-water, fiber-fines, fiber-additives, fines-additives, etc., are very important in these heterogeneous samples giving rise to complex shear mechanism that are different from classical slurry systems. The flow properties of the pulp suspensions are important for the optimal functionality of most unit operations in pulp and paper- making.The aim of this project is to develop a novel device to study pulp suspensions behavior and to explore two potential uses for the new device: the improvement on equipment design and wet end chemistry optimization. The identified benefits are: pumping energy cost saving of 19%; maintenance cost reduction by 2%; performance improvement in pulp processing, which also improves product quality; and potential cost reduction by means of wet end optimization.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'WIND TURBINES WITH ADVANCED STATIC VAR COMPENSATION FOR WEAK GRIDS' (WINDDRIVER).

assistant: **Innovation**

The project involves the demonstration of a wind system which can be safely and economically installed at a weak point in the electricity grid.The energy technology objectives of the project are to :- demonstrate the efficient integration of an advanced forced commutated converter with a wind turbine- demonstrate the noise reduction of a novel blade design, allowing turbines to be located closer to dwellings reducing the connection distance and improving the environmental acceptability of wind turbines.- demonstrate that the system complies with codes such as EN50160 - Voltage characteristics of electricity supplied by public distribution systems - low static voltage disturbance, and low flicker even on weak grids.- provide data to verify models of wind turbine integration developed under the EU funded Joule programme.The Winddriver system uses stall regulated wind turbines with advanced force commutated converters to provide an electrical output which will cause minimal disturbance to a weak grid. The wind turbine incorporates noise reduced blades to minimise the environmental impact of the system.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fifth Framework proposal on 'Integrated approaches to the sustainable management of xylella diseases of citrus and coffee'.

assistant: **Concept**

An integrated management system will be developed for diseases caused by Xylella fastidiosa in citrus (Citrus variegated Chlorosis - CVC) and coffee (Coffee Leaf Scorch - CLS) based on:(i) the use of insecticides for vector control only after possible infection periods for Xylella have been identified;(ii) the optimum amount and ratio of N-P-K fertiliser and the avoidance of water stress;(iii) the pruning of twigs showing initial disease symptoms. In field experiments, the temporal progress and the spatial spread of CVC and CLS will be characterised and modelled. The sharpshooter vectors of X. fastidious in coffee will be identified and the transmission of the pathogen from coffee to citrus and vice versa will be checked. The genetic diversity of the pathogen in both crops will be estimated using molecular techniques to unveil the phylogenetic relationship between the CVCand CLS strains.