RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Genetic pathways for the prediction of the effects of irradiation - European normal and tumour tissue bank' under Fifth Framework.

assistant: **Concept**

In synergy with RTD Project GENEPI 1, a tissue bank, including lymphocytes and skin biopsies and a database will be created as essential infrastructure for present and future genetic research in the field of radiation protection and health. From normal tissues obtained from up to 2000 individuals (GENEPI-1) RNA,DNA and proteins will be extracted, frozen, catalogued and stored. Networking systems and IT for normalisation and storage of data in a central database, including gene expression profiles and a web-based information /access system will be established. Modern statistical tools and high throughput computational biology will be applied for multiplexed data processing and analysis. Protocols for use and access will be developed and ethical and legal issues addressed. The tissue bank will remain open for 10 years until tissues from at least 10000individuals have been collected.The overall aim of the project is to create & maintain a collection of frozen normal tissues from the participating partners in WP4 of GENEPI-1.This bank will serve as a source of biological material for determination of genes, proteins, and molecular pathways responsible for the variation of normal tissue response to radiation. The bank will preserve material such that DNA, RNA & proteins that can be isolated and applied to the recent and continuing developments in genomics, proteomics & bio informatics. This includes techniques such as DNA sequencing, expression profiling with micro-arrays, single-nucleotide polymorphism (SNP) &mass-spectrometry protein analysis. In parallel an IT infrastructure linking the research institutes, including a web-based access & information system, will be developed and a database set up containing clinical, tissue & genetic data.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'ERA-NET Plus on Electromobility' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

The growing awareness of necessary changes and effective measures that can prevent, or at least, limit climate change has in many countries led to substantially intensified efforts in research and development. The dominant objective is to reduce fossil fuel consumption - therefore low carbon mobility, with electric mobility in the first place, is considered as a promising way to meet the challenge of future petrol scarcity.With the transnational call Electromobility+, public research programmes from 11 European countries and regions come together to give to research the objective of preparing a long-term horizon, one which will follow this current hype phase.Thus, Electromobility+ will contribute to the creation of long-lasting conditions for the development of electric mobility in Europe on the horizon of 2025. The joint initiative is geared to analyse, to consolidate and to prolong developments within the context of electromobility which are going to appear from 2010 on and so strongly contribute to shape the European electromobility of tomorrow.Within Electromobility+, research programmes from 11 European countries and regions are bringing together more than 15 M€ of public funding within the framework of the proposed ERA-Net Plus initiative. The European Commission may additionally contribute up to 33 % of the total national funding to the funding of trans-national projects (i.e. about 7 M€).Electromobility+ is a contribution of European countries and regions to the European Green Cars Initiative. The main goal is to provide a basis for a long-term platform on electric mobility in Europe.The objectives of Electromobility+ can be summarised as follows1.The establishment of sustainable and effective structures for cooperation and coordination of research in the field
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Prediction and validation of in vivo dendritic processing' to be submitted under Horizon 2020.

assistant: **Abstract**

Integration of synaptic input by single neurons is fundamental to computation in the brain. The output of every cell within a network is shaped by the elaborate morphology of its dendritic tree, and a suite of biophysical mechanisms that confer nonlinear processing capabilities. Over past decades, a remarkable synergy between theory and experiment has elucidated key strategies by which single-cell processing could thus enhance the neural code. However, a critical gap in current understanding remains: which operations from the vast dendritic repertoire are actually employed in vivo? One major obstacle to addressing this problem is that the statistics of in vivo input patterns are largely unknown. Thus, it is unclear how salient information is presented to the dendrites of a neuron, and by extension, what mechanisms are used for its transduction to action potential output at the axon.I aim to answer these questions by combining my expertise with that of the host lab to formulate theoretical predictions and then validate them with in vivo experiments. Specifically, I will construct a computational model of a cortical neuron that learns to discriminate synaptic input patterns, and use it to discover the optimal scheme for encoding and decoding information. I will thus predict the spatiotemporal patterns of synaptic input to stimulus-tuned neurons, and the biophysical mechanisms through which this information can be extracted. I will then test these predictions in primary visual cortex of awake behaving mice through two-photon dual-colour imaging of presynaptic glutamate release and postsynaptic calcium dynamics. By relating the algorithmic and biological function of neurons in the living brain, I anticipate this project will yield important insights into general principles
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for '12th meeting of directors of fisheries research organisation of EU' (MODOFRO).

assistant: **Innovation**

The 12ø Meeting of Directors of Fisheries Research Organisations of the European Union will take place in Vigo, Spain, during 5 days in early June 2002, coinciding with the Spanish Presidency of EU. As in previous meetings, each Member State Fishery research organisation will be represented by 2 members. Representatives of the Commission (4), invited keynote speakers (4) and representatives from the fishing industry will participate as well, This will be the 12th of a series of Meetings dedicated to the dialogue between fisheries research organisations represented by their Directors-, the Commission and the fishing industry and other stakeholders.The main issues related to research on fisheries and aquaculture in the EU will be addressed and discussed during the programmed sessions of the meeting. The topics to deal with will be grouped under this headings: 1 6th UE Framework programme: Implications for fisheries and aquaculture research.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fifth Framework proposal on 'Determination of conditions to prevent weathering due to condensation, particle deposition and micro-organism growth on ancient stained glass windows with protective glazing'.

assistant: **Concept**

The research made in Sainte Chapelle-France & Cathedral of Cologne-Germany with a multidisciplinary team, is based on both laboratory study/simulation and field surveys. The final goal is to provide methodology and thresholds of danger to preserve stained glass windows with protective glazing. It will be concentrated on monitoring, evaluation and improvement of the environment. Climate and the microclimate will be monitored with automatic devices and field surveys. A new dew point sensor connected with an alarm system will be tested and modified to control the danger of condensation inside the interspace between the two glasses. The glass surface deposition and air content of anthropogenic and natural particles and the microorganisms' growth on samples and the microbial contamination will be studied. Glass sensors will be installed inside, in the interspace and outside Analysis of originals and simulation tests will be done.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Development of a low cost process for the manufacture of storage and pressure vessels using novel composite thermoplastic materials (COMPOSITEFOAM)' to be submitted under Fifth Framework.

assistant: **Abstract**

The project has resulted in the manufacture of a steel concept tool, produced via thermal spray technology. The tooling incorporates conformal channels in the outer shell enabling direct heating and cooling using thermal oil. A radio telemetry based, temperature measurement and logging system has been used in process trials, for control of the heating and cooling cycle. The success of the radio telemetry system will lead to control of the rotational moulding process by temperature rather than time. Process trials using the novel tooling have successfully demonstrated the proof of principle of the tooling, with both foamed and un-foamed polyethylene. The heating and cooling response of the novel tooling was determined and found to be repeatable. Thermal imaging has been used to determine the thermal transfer characteristics of the sprayed steel tooling, demonstrating that the variation in temperature across the tool surface and the temperature lag during heating, are negligible.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Replenishing the limited Aluminium reservoir of MAX phase coatings in harsh environments', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Phase stability is likely to be the single most important specification which determines the  lifetime of materials operating in extreme environments. Whether a phase will react with the environment or decompose at high temperature is an essential limitation for the use of the material for any given applications. MAX phases are a family of layered ternary ceramics currently being developed for extreme environment applications because of their tolerance to heat, their ceramic-metallic hybrid properties and more importantly because of their self-healing behaviour. However, similarly to other self-healing materials, aluminium-based MAX phases tend to decompose locally as soon as Al reacts to form the protective oxide scale. Upon decomposition, the  unique set of properties deteriorates rapidly.The REALMAX project will tackle the outward diffusion of Al from MAX phase coatings in oxidising environments, by providing solutions for supplying Al to the coating from a MAX phase substrate which will act as Al-reservoir. Furthermore, the REALMAX project will engage in ground-breaking research to develop multifunctional coatings and validate the concept of “high-entropy” MAX phases. In fact, these multielement MAX phases constitute a new and exciting research line which is in the early stages of being developed.The REALMAX project will be carried out by the experienced researcher (ER) who has gained experience on MAX phase coatings during her current postdoctoral position. The ER has aligned a team of experts in MAX phases, coatings and material processing who will collaborate to offer innovative solutions to increase phase stability in MAX phase systems while mentoring her to achieve her career plans. In fact, she will be well positioned to pursue her academic career in Europe, w
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'TELEMATICS APPLICATIONS AND STRATEGIES COMBATING SOCIAL AND ECONOMIC EXCLUSION'.

assistant: **Objectives**

PERIPHERA seeks to tackle training and employment for groups which risk exclusion for economic or social reasons or because of geographical isolation through the availability of telematics applications designed to cope with the needs of these groups. Their employment needs will be addressed through new ways of working to reduce this kind of marginalisation. Telematics training will be offered for a specific peripheral group at different centres which will then provide access to telematics for teleworking, and support for employment through self-help initiatives. Partners will work towards a common approach in integration of all such groups, sharing their individual experience and results.Increasing collaboration of European Authorities and Service Providers ensures equality of access and opportunity to European citizens in the single market. However, because of special problems, some groups of citizens are presently excluded to the European periphery. Periphera addresses training and employment needs of the cultural, geographical, social, and economic periphery. Unemployed, cultural minorities, migrants, disabled people and those whose circumstances exclude them from participation in the full benefits of European society are addressed. Their employment needs will be answered through new ways of working to reduce marginalisation. The project joins experts and providers from Member States, plus potential end users of Telematics and Teleworking services, to address the integration of peripheral groups. Implementation of telecentres will provide training in skills including teleworking, plus access to technologies for exploitation of 'new opportunities for working' through 'new ways of working' via self-help. In seven sites, a centre will provide training in Telematics for
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'High-Precision Gravitational Wave Physics from a Worldline Quantum Field Theory' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

This project will determine the gravitational waves emitted in the encounter of two black holes or neutron stars in our universe at highest-precision. The gravitational waves emerging from such violent mergers are now routinely detected at the LIGO-Virgo-KAGRA observatories since their discovery in 2016. With the presently planed third generation of observatories the experimental accuracy will dramatically increase. Theoretical predictions for the emitted waveforms at highest-precision are therefore needed in order to determine the source parameters, such as masses, spins and intrinsic parameters of the two compact objects. Obtaining these waveforms requires solving the extremely difficult field equations of Einstein’s gravity. Major obstacles are the inclusion of radiative and spin effects at high-precision, as well as access to the strong gravity regime. Together with my research group, I have recently devised a novel quantum formalism to attack this classical physics scenario – worldline quantum field theory – that is methodologically rooted in elementary particle physics. It is the leading formalism to compute observables in the gravitational scattering of spinning black holes and neutron stars. My goal is to extend the scope of worldline quantum field theory to include radiative, higher spin and tidal effects, that discriminate between black holes and neutron stars. Moreover, I will uncover a hidden supersymmetry in the scattering of two spinning black holes. Finally, by matching to curved space-times I will develop theoretical tools that apply to strong gravitational fields as they arise close to the merger. These are presently unreachable by analytical methods. Our results will set the basis to test Einstein’s theory of gravity in extreme regions, possibly uncove
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Control of specificity in the NF-kB system' will create measurable scientific, societal and economic impact aligned with Sixth Framework.

assistant: **Impact**

The Nuclear Factor kappa B (NF-kB) is a family of five structurally-related transcription factors that, in order to function, associate in homo- and hetero-dimeric form. Upon activation, NF-kB dimmers traslocate into the nucleus, bind to target sequences (k B sites) in the promoters of several genes, and activate transcription. The aim of this proposal is to elucidate the molecular mechanisms which confer specificity to NF-kB-dependent gene activation. In vitro studies have shown that the different NF-kB dimmers have almost the same ability to bind any given kB site. However, analyses of knock-out mice and cells have shown that each NF-kB dimmer regulates specific targets (although some genes respond redundantly to several NF-kB species). Since in most cell types multiple NF-kB subunits are co-expressed, with the resulting presence of a wide variety of dimmers at the same time, we will asses the contribution of each specific dimmer to determining a particular transcriptional phenotype. In the NF-kB system it i s possible to distinguish two kinds of specificity: one is at the promoter level, whereby different promoters within the same cell recruit distinct NF-kB dimmers. The second is cell type specificity, in which the same NF-kB-dependent gene behaves different ly in different cells. To investigate the molecular mechanisms underlying these phenomena, we will focus on differences in the chromatin structure of target promoters, and on co-factors which regulate NF-kB recruitment aand activity. We will systematically ly analyse histone modifications, and the activities of histone-modifying enzymes, at NF-kB-dependent gene promoters. In addition, we will isolate NF-kB-containing protein complexes from the nuclei of different cell types, and those directly bound to spec ific
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Active Target and Time Projection Chamber'.

assistant: **Concept**

The active target and time projection chamber (ACTAR TPC) is a novel gas-filled detection system that will permit new studies into the structure and decays of the most exotic nuclei.  The use of a gas volume that acts as a sensitive detection medium and as the reaction target itself (an “active target”) offers considerable advantages over traditional nuclear physics detectors and techniques.  In high-energy physics, TPC detectors have found profitable applications but their use in nuclear physics has been limited.  With the ACTAR TPC design, individual detection pad sizes of 2 mm are the smallest ever attempted in either discipline but is a requirement for high-efficiency and high-resolution nuclear spectroscopy.  The corresponding large number of electronic channels (16000 from a surface of only 25×25 cm) requires new developments in high-density electronics and data-acquisition systems that are not yet available in the nuclear physics domain.  New experiments in regions of the nuclear chart that cannot be presently contemplated will become feasible with ACTAR TPC.