RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'From Data-based to Model-based AI: Representation Learning for Planning' (RLeap) under Horizon 2020.

assistant: **Objectives**

Two of the main research threads in AI revolve around the development of data-based learners capable of inferring behavior and  functions from experience and data, and model-based solvers capable of tackling well-defined but intractable models like SAT, classical planning, and Bayesian networks. Learners, and in particular deep learners, have achieved considerable success but result in black boxes that do not have the flexibility, transparency, and generality of their model-based counterparts. Solvers, on the other hand, require models which are hard to build by hand. RLeap is aimed at achieving an integration of learners and solvers in the context of planning by addressing and solving the problem of learning first-order planning representations from raw perceptions alone without using any prior symbolic knowledge. The ability to construct first-order symbolic representations and using them for expressing, communicating, achieving, and recognizing goals is a main component of human intelligence and a fundamental, open research problem in AI.  The success of RLeap requires the development of radically new ideas and methods that will build on those of a number of related areas that include planning,  learning, knowledge representation, combinatorial optimization and SAT. The approach to be pursued  is based on a clear separation  between learning the  symbolic representations themselves, that is cast as a combinatorial problem,  and learning the interpretations of those representations, that is cast as a supervised learning problem from targets obtained from the first part. RLeap will address both problems, not just in the planning setting but in the generalized planning setting as well where plans are general strategies. The project can make a significant difference in h
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Impact of climate change on zoonotic vector-borne diseases and their potential transmission increase and introduction risk: An innovative approach with a selected disease model' (FascioClim) under Horizon Europe.

assistant: **Objectives**

Vector-borne diseases (VBDs) pose a major threat to the health of societies around the world, with more than 80% of the global population at risk of at least one major VBD. VBDs are particularly susceptible to the effects of climate change, which will affect the distribution of vectors, the spatial and temporal patterns of the diseases vectors transmit, as well as the efficiency and intensity with which vectors transmit pathogens. A climate-driven phenomenon of outbreaks of VBDs, many of them zoonotic, is occurring worldwide, and Europe is not the exception. In this complex scenario, as climate change accelerates, globalisation spreads vectors and pathogens, and other human-caused disturbances increase, it is urgent to assess and predict impacts on disease transmission. We aim to assess the response of zoonotic VBDs to climate change and the potential threat it entails to Europe by using fascioliasis as a selected model. Fascioliasis, a complex zoonotic snail-borne disease, represents an ideal model as it has a low reservoir specificity, a high number of snail host species, and has already evinced being influenced by climate and global changes. We propose an integrative modelling framework for fascioliasis transmission: we will apply some innovative ideas in the field of ecological niche modelling combined with the use of climatic forecast indices, to identify the overlap between niches of fasciolids and snail hosts, and determine the area under risk of transmission. In addition, we will provide open-source tools accessible to the health sector. We expect this innovative ensemble of modelling approaches could be applied for assessing climate change impact on other zoonotic VBDs (in particular schistosomiasis, other snail-borne disease, but also mosquito- and tick-borne
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Youth Entrepreneurship in Portugal and the UK'.

assistant: **Objectives**

Promoting youth entrepreneurship has become a crucial EU strategy in addressing high unemployment rates. Statistics have indicated that, although young people show interest in starting up ventures, there is a big gap between intentions and concretization. Additionally, entrepreneurial intentions/activities seem to vary largely across European countries. Research on determinants of entrepreneurship has focused mainly in macro-economic and individual level factors. The analysis of entrepreneurship in cultural terms has remained elusive.Thus, the main aim of the Youth Entrepreneurs proposal is to also explore cultural/contextual factors associated with fostering/challenging youth entrepreneurship. More precisely, it is intended to: 1) analyse and compare the experiences and characteristics of youth entrepreneurship in two economically and culturally distinct European countries (Portugal and UK); 2) to apply a distinctive participatory approach that will engage young people and stakeholders in the research process; 3) implement outreach activities designed to maximise impact of the findings. Using an interdisciplinary team, this project aims to bring together insights from psychology, geography/sociology and business studies. It will be applied an innovative mixed and comparative methodology, combining quantitative, qualitative (e.g. focus-groups, semi-structured interviews and biographical narrative interviews), and participatory (e.g. workshops) approaches. The results of the project will provide comprehensive knowledge about different types of factors (e.g. familiar, financial) influencing entrepreneurship, and outline support policies that better match the real needs of young people in each country.This project will be carried out in Keele University, which has strong e
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'QM/MM modelling of human cytochrome P450 isoforms', explaining its relevance to EU policy priorities under Sixth Framework.

assistant: **Impact**

The research proposal focuses on the modeling of human cytochrome P450 (CYP) enzymes. CYPs protect organisms against xenobiotics, metabolize drugs and play an essential role in the biosynthesis of steroid hormones.Despite the fact that CYPs metabolize more than 90% of the drugs in man, the molecular basis of their catalytic activity is not understood yet. Our project aims to apply the most recent developments of computational chemistry, state-of-art QM/MM methods to address fundamental questions related to the activity of CYPs.- Inhibition: Bergamottin, one of the major furanocoumarins found in grapefruit juice, is an effective mechanism-based inhibitor of CYP3A4. Our aim is to elucidate the exact reaction mechanism of inhibition/inactivation of CYP3A4 by bergamottin. - Substrate and regioselectivity. CYP enzymes possess an overlapping substrate selectivity but with strong regioselectivity. We plan to compare the reactivity of CYP2D6 and CYP3A4 by modelling the metabolism of Dextromethorphan by the two isoforms.- Polymorphism. CYPs have various alleles, and the different variants of the enzyme display significant differences in activity which is directly related to differences in the metabolism of drugs among individuals.This has serious implications on the effective drug dose needed to treat patients. Quantum chemistry allows us to perform mutations on the enzyme in silico and our goal is to model and compare the reactivity of the wild-type enzyme (CYP2D6-wt), the CYP2D6-E mutant with no activity, an d the CYP2D6-J mutant with reduced activity.Our project is considered to be highly important in European dimensions and it will deliver added value to the whole community from the following points of view- as a part of the Structuring European Research Area- in relation to
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'AUTOCONFIGURABLE METROLOGICAL MEASUREMENT SYSTEM FOR PRODUCTION LINES IN AUTOMOBILE PIECES PROVIDERS' under Horizon 2020.

assistant: **Concept**

WIP has detected that the companies engaged in the manufacture of metal assemblies for automobile, providers of a lot of parts to largest car manufacturers, have several problems in the measurement and calibration of its pieces, because much of this provision is the result of processes of stamping and welding. These processes are so aggressive that deform the components, causing a dimensional uncertainty gives rise to a problem unresolved: Many of the manufactured parts are large and have complicated geometries, therefore, it is impossible to measure them in the production line. Industrial measurement systems are generally large machines (coordinate system) located in temperature controlled laboratories.  Current solutions are able to measure very few parts per time unit. These laboratories are typically used inspection of a part of each lot in a production, assuming that the assembly process is effective enough to not have to measure 100 % of them. But this is not this case, WIP has since found that this rule was valid in the past, but the specifications (tolerances) that automobile companies require to their suppliers (tolerances of tenths of a millimeter in large welding pieces), are destroying this measurement model. Producing a batch of defective pieces, with erroneous measurements, may result loss of entire batch, it would have to make the batch again (large stress in production line in the factory, the viability of the line is under doubts, etc) and this would involve a high cost. Moreover, confidence would be lost with the end customer.Therefore, due to these deficiencies in the measurement of pieces, WIP has identified a great business opportunity, especially in the field of automobile suppliers.WIP aims to apply to the SME Instrument for the large-scale commer
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Characterization of Nod factor receptor LYK3 protein-interaction networks during early symbiotic signaling in Medicago truncatula' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

Legumes are able to enter nitrogen-fixing symbiosis with rhizobial bacteria. The use of legumes in agriculture offers a number of advantages, including improvement of soil quality and the avoidance of chemical nitrogen ferlizers, which makes them a key element in sustainable agricultural systems. The rhizobium-legume symbiosis provides a unique experimental system in which to interrogate a signal transduction pathway which affects many fundamental aspects of plant biology. Host perception of rhizobial elicitors, called “Nod Factors”, trigger fluctuations in calcium, alterations in the cytoskeleton, and membrane trafficking. These processes culminate in the formation of a new plant organ specialized in nitrogen fixation called nodule. In recent years, genetic screens in the model legume Medicago truncatula have led to the identification of a number of mutants affected in early signaling responses. Among the genes identified are NFP and LYK3, which encode Nod factor receptor kinases essential for nodulation. Nevertheless, how these receptors perceive and relay the Nod factor signal to each other and to unidentified, downstream effectors of nodule development remains to be established. The main research objective of SymBioSignal is to identify novel elements of the Nod factor signal transduction pathway by analyzing the proteins that interact with the Nod factor receptor kinase LYK3 in M. truncatula. This will involve: (1) the identification of protein targets using tandem affinity purification approaches in combination with mass spectrometry; (2) the characterization of the functional relevance of the interacting proteins and their relationship to early symbiotic responses by means of reverse genetic, cell biological and biochemical studies. Knowledge gained in this proje
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Interactive regulation of phytoplankton succession by physical forcing and internal phosphorus loading: a comparative study in eutrophic freshwater lakes' to be submitted under Fifth Framework.

assistant: **Abstract**

Problems to be solvedDeterioration of water quality of freshwater lakes, as a consequence of man-made perturbations such as water level regulations, pollution and food web manipulations is a commonly observed phenomenon of our times. In the extreme case of long lasting elevated pollution loads and the affluence of bio-available phosphorus (BAP) the lake ecosystem responded with increasing algal biomass and a species shift to nitrogen fixing cyan bacteria. After becoming aware of phosphorus (P) as the driving force of eutrophication the reduction of external P loading became the primary management target. However, in many cases even a drastic reduction of the external P-loading did not succeed in improving water quality since P-recycling from bottom sediments sufficed to provide the amount of BAP necessary to support algae blooms. The question arises in how far this development can be reversed and algae diversity restored. Considering the variety of available remedial measures, an experimental procedure to predict water quality changes is needed to arrive at the decision upon the optimum management strategy. The proposed study complies with this requirement through an experimental approach based upon the control of environmental parameters such as nutrient loading or resuspension in large enclosures, while monitoring phytoplankton succession. Our proposal enforces community water policy aimed to achieve sustainability of aquatic systems by responding to the following Water Framework Directives: eutrophication control (91/271/EEC) and safeguarding human health by establishing strict standards for the quality of water intended for human consumption (80/778/EEC).Scientific objectives and approachUsing a novel monitoring tool for phytoplankton diversity and biomass the prese
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Expanding Integrated Assessment Modelling: Comprehensive and Comprehensible Science for Sustainable, Co-Created Climate Action' (2021-2027), addressing dissemination and exploitation.

assistant: **Impact**

Neither the first round of Nationally Determined Contributions (NDCs) nor currently implemented climate policies are on track to meeting the Paris Agreements objectives. Parties are expected to increase their ambition and produce new NDCs covering the post-2030 period. The design of a multi-dimensional set of policy measures that comprise countries climate policy agendas is supported by equally diverse integrated assessment modelling (IAM) activities. Notwithstanding the recent progress in the IAM literature and scenario space, the modelling world has fallen short of its promise to include non-scientists in its process; to account for individual choices and lifestyle changes that are indirectly narrated as assumptions not interacting with the vividly modelled technology-economy-environment-policy flows; and to place climate action as a cross-cutting theme in the sustainability spectrum.IAM COMPACT will support the assessment of global climate goals, progress, and feasibility space, as well as the design of the next round of NDCs and policy planning beyond 2030 for major emitters and non-high-income countries. We will use a diverse ensemble of models, tools, and insights from social and political sciences and operations research, and will integrate bodies of knowledge to co-create the research process and enhance transparency, robustness, and policy relevance. We will explore the role of structural changes in major emitting sectors and of political, behaviour, and social aspects in mitigation; quantify factors promoting or hindering climate neutrality; and account for extreme scenarios, to deliver a range of global and national pathways that are environmentally effective, economically viable, politically feasible, and socially desirable. In doing so, we will fully accoun
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Promoting participation of high-tech research-intensive SMEs in Health' (2007-2013).

assistant: **Concept**

Fit for Health aims to sustainably enhance the participation of European small or medium-sized enterprises (SMEs) in Calls for the FP7 Health Theme. Focusing on research-intensive, high technology SMEs, the project offers targeted support measures, covering the entire innovation pipeline of the Health sector. Key assets of Fit for Health are highly qualified consultancy, hands-on trainings, effective SME-academia matchmaking and guidance to  strategic use of FP7 by SMEs and clusters. Particular attention will be given to SMEs in enlarged Europe, Acceding and Candidate countries. SMEs and researchers will be supported during all phases of FP7-projects, including consortium building, proposal writing, grant negotiation, project management and efficient valorisation of project results. Cooperation between SMEs and academia will be strongly encouraged by dedicated services and tools. A well-established, highly visible database and a sophisticated matchmaking-tool, already proven in preceding initiatives, will support the formation of competitive project consortia. Partnering Days and Virtual Brokerage Events will provide excellent interaction platforms for SMEs and academia. Target group-specific on-site and virtual trainings for FP7 Newcomers, Applicants and participants of funded FP7 projects will be a hallmark of the project. “Valorisation Trainings” and specific Partnering Events will support SMEs and researchers in successfully exploiting project results. Strategy meetings and trainings will support SMEs and clusters for a strategic, sustainable approach towards FP7. The consortium of 27 partners from 22 countries joins highly experienced FP7 NCPs for “Health” and “SMEs” with renowned innovation experts and trainers, ensuring excellent coverage of the entire innovation
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Advanced materials and devices for hybrid spin coherent technologies' (ASCENT), addressing dissemination and exploitation.

assistant: **Impact**

The property of spin has been harnessed in an array of revolutionary technologies, from nuclear spins in magnetic resonance imaging to spintronics in magnetic recording media. Nature at its deepest level is quantum mechanical and spins are capable of demonstrating superposition and entanglement, yet such coherent properties have not yet been fully exploited. The exquisite control over materials fabrication and spin control techniques has reached a maturity where spintronics can go beyond purely classical effects and begin to fully exploit these quantum properties. Potential applications range from quantum information processors, including the transmission of quantum information via itinerant electron spins, single microwave photon storage within spin ensembles, and a new generation of sensors exploiting entanglement to yield fundamentally enhanced precision.The aim of ASCENT is to develop materials and devices in which electron and nuclear spins exhibit long-lived coherent quantum behaviour and interactions which can be harnessed for technological purposes. Specifically, ASCENT will exploit in range of condensed matter systems from molecular materials to silicon-based structures, the possibility of transiently generating and removing electron spins in the vicinity of nuclear spins. The project represents a new and promising direction for the development of coherent interactions between spins in materials, and one which builds upon foundations I have established in my earlier work, often supported by preliminary investigations. Strong interactions with theory throughout this project will provide insights to refine and improve the experiments. In addition to direct applications in quantum technologies, the insights and methodology gained will be fed back into the wider fi