RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Hydrated Electrons from iRradiated metal-free semicOnductors for Per- and poly-FluoroAlkyl Substances degradation in water'.

assistant: **Objectives**

Per- and poly-fluoroalkyl substances (PFAS) are a group of man-made chemicals produced for several applications, ubiquitous in water bodies close to industrialised regions, and with recognized associated issues to human health (e.g. carcinogenicity). Being among the most recalcitrant class of emerging contaminants, an efficient water treatment able to degrade PFAS will represent an outstanding technology, not only for the recovery of already contaminated sites (impressively spread in Europe), but also for drinking- and waste-water treatment plants. The project proposal, “Hydrated Electrons from iRradiated metal-free semicOnductors for PFAS degradation in water (HERO4PFAS)”, focuses on the development and investigation of wide band gap semiconductors able to photo-produce hydrated electrons under ultraviolet (UV) light to eliminate PFAS from water. The main goal will be to evolve from the state-of-the-art homogeneous advanced reduction processes (ARPs) towards heterogeneous systems to be employed in real cases. Since very expensive materials are required to photo-produce hydrated electrons (e.g. diamond-carbon), in this project low-cost photocatalysts based on hexagonal boron nitride will be prepared, and their ability in the degradation of PFAS studied under different conditions (type of irradiation, pH, dissolved oxygen). Systems based on heterogeneous UV-ARP will be implemented for the removal of PFAS from retentate streams of advanced membrane filtration systems and coupled with advanced oxidation processes in a holistic treatment train able to reach the complete PFAS mineralization. HERO4PFAS will fill the gap between PFAS degradation and the development of a cost-efficient heterogeneous photo-ARP.With the support of my supervisor (Prof. Minella) at University of Tu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Ecology of anaerobic methane oxidizing microbes' (ECO-MOM), addressing dissemination and exploitation.

assistant: **Impact**

For over a century it was believed that methane (CH4) could only be oxidized by micro-organisms in the presence of oxygen. The possibility of nitrate-dependent or metal-dependent anaerobic oxidation of CH4 (AOM) was generally dismissed. However, about 6 years ago the microbes responsible for the nitrate-AOM reaction were discovered. This was followed by molecular approaches that resulted in the identification of the responsible Methylomirabilis oxyfera bacteria. Recently, the widespread environmental occurrence of these bacteria was demonstrated leading to the realization that AOM may play a significant role in the CH4 and nitrogen cycles. M. oxyfera is a unique microbe with unusual properties that we only begin to understand: the production of oxygen from NO by a putative NO dismutase and a very unusual polygonal cell shape. Even less is known about metals (Fe3+ or Mn4+) as electron acceptors for AOM. The aim of this project is to obtain a fundamental understanding of the metabolism and ecological importance of the M. oxyfera bacteria, and to enrich new metal-dependent AOM microbes. Such understanding contributes directly to our environment and economy because AOM is a new sustainable opportunity for nitrogen removal from wastewater. The results will show how the CH4, nitrogen and iron cycles are connected and may lead to new ways of mitigating methane emission. The biodiversity and contribution of AOM-microbes to the biogeochemical cycles in oxygen-limited ecosystems will be investigated, and new metal-AOM enrichments will be performed. Together the environmental and metabolic data will help to understand how and to what extent AOM-microbes contribute to the biogeochemical cycles and thus shape atmosphere of our planet. The research lines will employ state-of-the- art
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'A novel theory of human cortical microcircuit function:  Dedicated neuronal networks for fast cellular and synaptic computation'.

assistant: **Objectives**

How human neuronal circuits are organized to produce human cognition is poorly understood. We recently showed (Nature, 2021) that human neocortex contains neuron types not found in other mammals. My preliminary data show that large, human-specialized transcriptomically-defined cell types (t-types) have surprisingly fast processing of synaptic input to action potential output properties. Other human t-types show much slower input-output properties more akin to average mammalian neurons. These fast human-specialized t-types are selectively vulnerable in prevalent human brain disorders with cognitive decline. Mechanisms of fast input-output processing are unknown. We also do not know whether fast-processing neuron t-types form preferential synaptic networks dedicated to fast cortical processing, increasing cortical computational power to support human cognition. Here, I will test this novel concept addressing four fundamental questions: What mechanisms drive fast cellular input-output properties? What mechanisms underlie non-linear dendritic processing of synaptic input? How is coupling between distal dendritic synapses and soma controlled? Do human neuron t-types with fast input-output properties form preferential synaptic networks? These questions can only now be answered with our recent transcriptomic, morpho-electric Patch-seq analysis of adult human neuron t-types. Combined with dendritic and multi-patch recordings, molecular interventions, photonic approaches, and computational modeling, I will provide an unprecedented quantitative understanding of fast cellular computation mechanisms in human cortex supporting human cognition. First preliminary data suggest that biophysical properties of human-specialized neuron t-types and synapses are distinct. Understanding human
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Linking ILLegal WILDlife trade and biodiversity loss: new insights from digital media'.

assistant: **Concept**

Illegal wildlife trade (IWT) is increasing worldwide, with far reaching consequences for animal populations and ecosystems, as well as for human health and society. IWT is changing rapidly, and digital media has become one of its main channels. However, no systematic studies have characterized the magnitude and geographic range of IWT on digital media and the subsequent impacts on biodiversity conservation. Here, I will: (1) explore and quantify the global scale of IWT on digital media for endangered mammal and bird species; (2) identify geographic hotspots and explore the socio-economic drivers of IWT; and (3) identify top priority species for which the impact of individual offtake for IWT through digital media is higher in terms of population decline. To do so, I will focus on the digital trade of bird and mammal species included in Appendix I of CITES (Convention on International Trade in Endangered Species of Wild Fauna and Flora); since international trade for those species is not permitted. I will use state-of-the-art machine-learning algorithms to detect and quantify illegal trade of those species on several digital media platforms. I will integrate this information with potential geographic and socio-economic drivers of illegal wildlife trade to establish appropriate conservation planning strategies. Finally, I will carry out population models to understand the contribution of IWT to mortality rates and population trends. The proposed study combines artificial intelligence, social sciences and conservation science, thus providing a novel, multidisciplinary approach to understand the extent and patterns of IWT through digital media platforms and inform decision-making to ultimately help halt biodiversity loss.


**Keywords:** illegal wildlife trade,  E-commerce,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'The German Sources of Ecology' to be submitted under Horizon Europe.

assistant: **Abstract**

Originally, ‘ecology’ was more than just the name of a biological subdiscipline. When its inventor, the German biologist Ernst Haeckel, first coined the term (German: ‘Oecologie’) in his 1866 work General Morphology, he was in fact shaping the contours of a larger philosophical project rooted in German anthropology and aesthetics. The aim of this ERC research project is to uncover this forgotten enterprise and to assess its implications. To do so, it proposes a radical change of perspective, broadening the view from the scientific dimension emphasized by Haeckel’s successors to its philosophical sources. By analyzing Haeckel’s original interpretation of the metaphor of oikos (‘habitat’, ‘dwelling’) and oikeiosis (‘adaptation’, ‘appropriation’), the project traces the shift in emphasis from the viewpoint of an external and distant God to the living organism’s own capacities for adaptation and domestic ‘householding’; it examines the place of the human organism in this ecology, as a natural being, as a human housekeeper, as part of a larger household, and as an aesthetic spectator, representing and visualizing the world from within and from the terrestrial habitat. Using a transversal methodology situated at the intersection of conceptual history, history of philosophy, history of science, aesthetics and philology, Oecologie explores the context of the emergence of this first strand of ecological thought in nineteenth-century European evolutionism (1), its philosophical sources and its debt to earlier thinkers in the German tradition, such as Kant, Alexander von Humboldt and Goethe (2), its ambiguous history of reception both in Germany and abroad (3). Last but not least, it examines the actuality and relevance of such an ecology for environmental studies and the contempo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'The revolution in micro-granulation technology for eco-friendly, production efficient, superior ceramic tiles' (2014-2020).

assistant: **Concept**

Established in 1973, our company LB designs, develops and manufactures production machinery and turnkey manufacturing plants for the ceramic industry – from raw material handling equipment to manufacturing equipment for tiles. We also offer complete systems for the production of premixes for the building trade and for powder treatment in various industrial fields.Our latest development, the micro-granulation technology Migratech 4.0, will revolutionise the ceramic tile manufacture: it not only enhances product quality but drastically reduces the operation costs and the significant environmental impact associated to the process. Indeed, the “wet process”, predominantly used today in production of high quality ceramic tiles, consumes a large amount of water (dissipated but not recovered) and thermal energy (approx. 30% of the total manufacturing cost). There is therefore a growing need for a new process which can reduce the water and energy used in manufacture of ceramic tiles. Our solution for this need is Migratech 4.0, which provides the desired high-quality ceramic powder with homogenized particle size and low humidity; but with drastic reductions in used energy (-64%), water (-70%) and CO2 emissions (-64%) for a production costs of tile manufacture reduced by 30%. Migratech 4.0 will increase sustainability and competitiveness in the whole ceramic tile supply chain while allowing our company to grow with +€46.5 million accumulated gross profits in 5 years of exploitation.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Solid State Battery Smart & Structural Modular Integration into Vehicle through Flexible Module to Chassis Design' in the context of a Horizon Europe call.

assistant: **Objectives**

S4MILE project aims to support the large-scale introduction of electric vehicles by simplifying the vehicle structure and integrating the next-generation solid-state cells into the vehicle structure based on a disruptive and innovative ‘virtual’ module-to-chassis concept (VM2C) based on large structural ALU casting and composite unibodies. The size of the permanently installed battery is reduced using a novel swappable module design to increase the gravimetric and volumetric energy density of the unit in a safe and robust design. The solid-state technology, coupled with advanced thermal and pressure management systems, enables fast charging and long-range based on a reconfigurable battery management system (BMS), which facilitates maintainability, reparability and second life and ensures modularity and scalability of the design applicable to a range of small to medium size vehicles through a safe and efficient communication and operation with the vehicle controller. Advanced battery models based on a battery passport coupled with a thermal management system in a digital twin of the battery will ensure optimal operation and life and range extension while ensuring safety in all operating conditions. S4MILE builds upon large experience and prior projects to meet outstanding results capable of boosting the EU landscape in EVs and related sectors.


**Keywords:** Expandable Battery, Structural Integration, Solid-state Gen4, PTMS, ALU casting and composite unibodies, Fast Charging
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Human Antibody Responses to Viruses', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

In addition to polyreactive “natural antibodies” that act as the first line of defense against invading pathogens, “humoral memory” is composed of high affinity antibodies that mediate long-lived immunity against infectious agents, e.g., providing protection against re-infection. The molecular dissection of anti-pathogen B-cell responses using modern technologies to generate specific monoclonal antibodies allowed breakthrough discoveries on antiviral responses to Influenza and HIV. The goal of this proposal is to study memory B-cell antibody responses to human pathogens, especially viruses, by generating and characterizing envelope specific antibodies from infected patients. I propose three aims to address what I believe to be some of the most exciting questions in the field of antiviral B-cell immunity. I propose to study: (i) the development and dynamics of memory B-cell responses to HIV; (ii) the mucosal antibody response to HIV; (iii) the memory B-cell response to Chikungunya virus. The antibodies that will be produced may be of therapeutic interest, but more importantly, their characterization will lead to a better understanding of human antibody responses to infectious agents, and may uncover candidate immunogens for vaccine development.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Research & study of a new type of integrated check-out for personal shopping in superstores, adapted to new technology of container systems called smart-box' (1994-1998), addressing dissemination and exploitation.

assistant: **Impact**

This proposal is prepared with the help of an Exploratory Award obtained on January 1997 which included a Research Feasibility Study. Today, the first distribution channel for basic products is the supermarket channel. More than 100 000 000 consumers in Europe use this form of distribution and this number is constantly increasing. But the consumers complain frequently against the bad conditions of shopping in supermarket. To answer to this demand, we are proposing a totally new distribution process of goods and articles from the supermarket to the consumers' house: the SMARTBOX system. The SMARTBOX system is the combination of the SME Proposer A2 SMARTBOX and trolleys products with a new check out to be created. The SMARTBOX is a great environmentally friendly shopping concept already in use in England. By encouraging customers to use the returnable and reusable grocery boxes in conjunction with a revolutionary new trolley, SMARTBOX enables retailers to improve their customer service offer with a smarter way to shop. But this system does not use an adapted check out and is not totally efficient. The purpose of our project is to create a new type of check out to be adapted to the SMARTBOX products which would allow the customers to have better shopping conditions and the retailers to improve their service offer. This new check out should be compatible with both the SMARTBOX and the present plastic bags processes. Each of the partners attached to this project has the sufficient know how to create and realise the new components adapted to the SMARTBOX check out prototype and an other proposer (supermarket called Intermarché) has joined the partnership for a better definition and then a better exploitation of this new check out process. We use several times in this report t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Automated multi-level modeling of biological systems considering physico-chemical constraints' (AMBICON) targeting Seventh Framework.

assistant: **Abstract**

The aim to make biological phenomena predictable is the driving force of research in systems biology. The ability to simulate entire cellular systems in the computer would be of great benefit for the biotechnological production of medication and the development of personalized medicine. To this end, the development of mathematical models plays a central role. The horizontal integration of models developed for gene regulation, signal transduction, or metabolism into a broader picture of the cellular interplay belongs to the most challenging problems of this endeavor: Models need to be combined that have solely been developed for one particular aspect. Only based on a holistic and detailed description of all cellular processes reliable computer models can be created by incorporating physico-chemical constraints that limit the model to experimental and real-world conditions. The creation of individual models is still not straightforward. Due to the complexity of the systems and the ability to simultaneously quantify several thousands of biological entities, this approach can only be feasible with the help of precise automated methods that reduce the human effort for model creation to a minimum. This project aims to unify the existing theoretical approaches for model creation (MASS and AMUSE). The effectiveness of these methods will be validated in an application to large-scale metabolic data (evolved E. coli, human erythrocytes and platelets). The combined wet-lab/dry-lab research facility at the University of California, San Diego, (UCSD) provides an excellent environment for the training of the applicant: Hands-on experimentation practice and effective large-scale study design involving biologists and modelers will be valuable learning objectives for the later establishm