RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Low-pressure turbines and control equipment for wave energy converters' under Fourth Framework.

assistant: **Concept**

The intended research project will develop and test low pressure water turbines suitable for use in offshore wave energy converters (WEC). The turbines and the electric/hydraulic control systems will be optimised for use in the Wave Dragon - a 4 MW offshore WEC of the slack moored run-up type. Wave Dragon developed by the prime proposal, and the international patent application for this WEC were published in 1996. Low pressure turbines like the Ossberger cross-flow type and the Kaplan-propeller types have been commercial for a long time The existing turbines and the control equipment are nevertheless not suitable for use in WEC's, as pressure and water flow are strongly and rapidly fluctuating in offshore WEC's. The project will use computer modelling and large scale tank test of a simplified model of the Wave Dragon with working scale model turbines on board. These tests will be conducted at and by the Danish Maritime Institute. Development of turbines suitable for WEC's is a necessary step in the process of commercialising big offshore renewable enelgy plants like the Wave Dragon and thereby harness the vast energy resources in the European waters and in the oceans many places in the world, where the average power levels is high. Values of 70 kW wave-power pr. meter is not unusual !
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Genomics for Triticeae improvement' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

For many years the size and complexity of the wheat, barley and rye genomes have hampered the development of genomics and its application to produce Triticeae crops with improved composition and characteristics. Recently, however, new and more efficient scientific capabilities and resources have been developed that allows robust genomic programs to be established for the Triticeae. TriticeaeGenome is designed to achieve significant progresses in Triticeae genomics and support efficient breeding of improved varieties for the European agriculture by: - Constructing and anchoring physical maps from the wheat and barley group 1 and 3 chromosomes that carry a large number of important agronomic traits (e.g. disease resistance, yield and quality) - Isolating genes and QTLs underlying disease resistance, yield and quality traits in wheat and barley - Identifying and exploiting new alleles for the isolated genes through the use of natural and mutant populations as well as wild germplasm - Supporting the development of new varieties that meet farmer and consumer needs through molecular breeding - Developing new bioinformatic tools to structure, relate and comprehensively analyse the large scale genomics data gathered within the project and - Leading, coordinating and integrating Triticeae genomics research Triticeaegenome is developed as a main contribution to the international consortia efforts in constructing physical maps of barley and hexaploid wheat for improving plant breeding, accelerating gene and QTL isolation and setting up the foundation for future genome sequencing.  It will deliver novel information and tools to breeders and scientists for a better understanding of Triticeae genomes organization, evolution, and function thereby, providing a better understanding of t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Support to the Chair and Vice-Chairs of the ERC Scientific Council 2013' (ERCSC-CHAIRS-SUP2013) targeting Seventh Framework.

assistant: **Abstract**

The proposed Action will provide the necessary support to the Chair and Vice-Chairs of the European Research Council Scientific Council (ERC ScC) to achieve key milestones and deliverables of the ScC, which are required in the fifth year of implementation of the Ideas specific programme.The proposed project aims to support the ScC Chair and Vice-Chairs, who, like other ScC members, are acting in a part-time capacity, in the efficient and timely achievement of the ScC’s objectives in 2013. It will support and assist Professor Helga Nowotny, Chair of the ERC’s ScC, Professor Pavel Exner, and Professor Carl-Henrik Heldin, Vice-Chairs of the ERC’s ScC, in their diverse responsibilities which include the achievement of efficient and effective functioning of the ScC, its integrated operation together with the ERC Executive Agency (ERCEA), and effective interfacing with the scientific community, other funding agencies and the political institutions of the European Union. The project will provide administrative and research support ranging from secretarial tasks to assistance in developing policy papers related to the work of the Chair and Vice-Chairs of the ERC ScC for a period of one year.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Solar energy and pressure sensor based solution for truck weighing' (Sensolweighs) under Horizon 2020.

assistant: **Objectives**

Improving road safety is a prime objective of the European Union's transport policy. Overloading of lorries is one of the most common infringements found in road freight transport: one in three lorries controlled is overloaded by 10%-20% over safe legal weight limits making roads much less safe. European Directive 2015/719 establishes maximum gross vehicle weights and urges for regular weight checks for commercial vehicles in the 28 EU countries. Truck scales are therefore essential for hauliers or public authorities. In addition, accurate truck scales are key for businesses delivering their products on the road as they are used to determine the weight of bulk goods being bought and sold in truckload-sized quantities being a crucial part of the business transaction functioning much as a cash register. Currently, the construction work, infrastructure and time needed to install a truck scale in a company’s facility results in a highly expensive burden. In addition, connection to the electric grid is indispensable and the heavy materials used make the relocation of the scale a concern. This results in very expensive solutions hindering competitiveness. The previous scenario has encouraged Cogo Bilance s.r.l., an innovative company fruit of the merger of major brands in the Italian weighing industry, to develop Sensolweighs. Sensolweighs is a truck scale powered by solar energy (with wireless connection) giving the possibility to work off-grid in remote locations, based on an innovative hydraulic system to measure weight. Its light resistant materials make its relocation and installation an easy task, reducing costs by more than 32% with just 2% of the time currently needed to set up a truck scale. With 44% of goods transported by road in the EU and an annual growth of more
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Biomimetic synthesis of a novel nonadride natural product', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

Research objectives and content Recently two new biologically active natural products based on nonadridic structures were isolated and characterised. Retro-biosynthetic analysis indicates that these seemingly complex products may be derived from the dimerisation of two closely related and simpler anhydride sub-units.We wish to attempt to reduce the synthesis of nonadride derivatives (comparable to the isolated natural products), to a (4+6)-cycloaddition of suitable precursors as the key step of a short biomimetic synthetic approach.Alkenylated aconitic acid esters and maleic anhydride derivatives containing different sidechains should be obtained starting from dihalogenated maleic anhydride by two consecutive tin-based coupling reactions, or a tin-based coupling reaction and a subsequent addition/elimination reaction, using easy accessible organotin reagents under mild conditions. After consecutive deprotection, decarboxylation and deprotonation of the derived aconitic acid esters, or after deprotonation of suitable maleic anhydride derivatives, a suprafacial, suprafacial (4+6)-cycloaddition with aconitic acid esters should form nonadridic anions as key intermediates, which should be converted in situ into the desired products via intramolecular cyclisation. Training content (objective, benefit and expected impact) The objective of this research project is to develop a straightforward synthesis of derivatives of biologically active natural products. The combination of various modern tranformations of organometallic chemistry to a total synthesis and the structural characterisation of intermediates and final products will extend the synthetic experience of the applicant. Links with industry / industrial relevance (22) The obtained products will be tested for biological a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Exploring the Molecular Properties of Atmospheric Freshly Nucleated Particles' (ExploreFNP) targeting Horizon Europe.

assistant: **Abstract**

Aerosol particles are ubiquitous constituents in the ambient atmosphere. Ultrafine particles (< 10 nm) show adverse effects on our public health, as inhalation leads to an elevated risk of lung- and cardiovascular diseases. Aerosol particles also influence the global climate, by scattering sunlight away from Earth's surface and acting as seeds for cloud droplet formation. Combined, these effects lead to an overall cooling of the Earth, directly counteracting the warming effect of greenhouse gases. According to the IPCC, aerosol particles pose the largest uncertainty in global climate forecast. This uncertainty is caused by the lack of understanding of the early growth behaviour of small (< 3 nm) particles. The largest source of aerosol particles (50-90%) is from nucleation of vapours in the air leading to a burst of freshly nucleated particles (FNPs) of 1-2 nm in size. However, even the basic fundamental properties of these FNPs remain unknown and cannot be studied using currently available experimental techniques. I propose a unique approach to target the properties of FNPs by applying a versatile suite of computational methods, ranging from quantum chemical calculations to application of conceptually new machine learning models. The scientific objectives are: 1) To determine the chemical composition and stability of FNPs. 2) To understand how FNPs evolve over time via exchange of vapours with the environment. 3) To investigate how FNPs transform as a consequence of chemical reactions occurring at the surface or inside the particles. The research will provide unprecedented insight into the molecular level properties of FNPs. This project will directly supply input parameters (chemical composition, thermodynamics and kinetics) for atmospheric models, which are crucial i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Customized porous structures and advanced testing for orthopedic implants' (CUSTOM) targeting Horizon Europe.

assistant: **Abstract**

The number of shoulder replacements is projected to increase by 300-400% between 2020 and 2040. With the current technology, 10% of those artificial shoulder implants will fail within the first 10 years of service, mainly due to soft tissue failure, infection, and implant loosening. The specific type and timescale of failure depends on the type of implant, patient age, and other patient specific metrics, but to avoid a similar exponential increase in revision surgeries, the next generation of implants must mitigate the known failure mechanisms. CUSTOM brings together all relevant academic and industrial expertise that enables a concept to clinical overview of emerging medical device technologies, and applies them to the shoulder implant as a use case. CUSTOM focuses on combining (1) computational tools that allow patient-specific design, (2) additive manufacturing to realize the custom, complex designs and structures and their further postprocessing to incorporate multi-functionality, and (3) blended in-silico and experimental testing to reduce the burden on experimental testing for certification. In doing so, CUSTOM can address the major failure mechanisms of current shoulder implants and improve their overall functionality and longevity. The project leverages this research as a tool to train the next generation of researchers in the necessary technical skills on design, manufacturing, testing, and certification. CUSTOM connects the researchers to all relevant stakeholders including surgeons, patients, researchers, as well as certification and regulation bodies, and combines it with soft skill training to develop transferable and entrepreneurial skills that are required to translate their research and ideas into the next generation of orthopaedic implants.


**Keywords
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Mechanism of homology search and the logic of homologous chromosome pairing in meiosis' (3D-loop) under Horizon 2020.

assistant: **Objectives**

Homologous recombination (HR) is a conserved DNA double-strand breaks (DSB) repair pathway that uniquely uses an intact DNA molecule as a template. Genome-wide homology search is carried out by a nucleoprotein filament (NPF) assembled on the ssDNA flanking the DSB, and whose product is a “D-loop” joint molecule. Beyond accurate DSB repair, this capacity of HR to spatially associates homologous molecules is also harnessed for homolog pairing in meiosis. The goal of “3D-loop” is to tackle two long lasting conundrums: the fundamental homology search mechanism that achieves accurate and efficient identification of a single homologous donor in the vastness of the genome and nucleus, and how this mechanism is adapted for the purpose of homologs attachment in meiosis. I overcame the main hurdle to study these core steps of HR by developing a suite of proximity ligation-based methodologies and experimental systems to physically detect joint molecules in yeast cells. It revealed elaborate regulation controlling D-loop dynamics and a novel class of joint molecules. This proposal builds upon these methodologies and findings to first address basic properties of the homology sampling process by the NPF and the role of D-loop dynamics, with the long-term goal to establish a quantitative framework of homology search in mitotic cells (WP1). Second, the meiosis-specific regulation of homology search leading to homolog pairing likely integrates chromosomal-scale information. Genome re-synthesis and engineering approaches will be deployed to (i) achieve a quantitative and dynamic cartography of the cytological and molecular events of meiosis over a large chromosomal region, (ii) probe cis-acting regulations at the chromosomal scale, and (iii) revisit the molecular paradigm for crossover f
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Context dependent sexual selection and the dynamics of colonisation' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

One of the main goals of evolutionary biology is to understand the causes and consequences of genetic and phenotypic diversity. A key factor in this process of diversification is the ability of individuals to invade, colonize and adapt to novel habitats. A common feature of colonisation events is the introduction of animals from multiple source populations. Such genetic admixture can have important implications for both the ecological and evolutionary potential of introduced populations, through increases in genetic and phenotypic variance. Despite this, the impact of admixture on the fitness of introduced populations has received little empirical validation. The key reason for this is a lack of studies which link genetic diversity of introduced populations and the agents of selection acting on that diversity. This proposal is an ambitious, but highly achievable, development of a novel and innovative multi-disciplinary research agenda aimed at addressing this fundamental issue in evolutionary biology. Specifically, I will combine genetic, physiological, and behavioural techniques in natural, semi-natural and laboratory settings using the invasive wall lizard, Podarcis muralis, to examine the genetic context dependence of sexual selection and its role on population persistence and evolutionary diversification during colonisation. Specifically, I will experimentally manipulate the genetic admixture of semi-natural populations to provide direct tests of the strength, direction, and targets of sexual selection under different genetic contexts during colonisation events. This data will be used to parameterize an individual-based simulation model to predict how sexual selection can affect the probability of colonization of novel habitats under low versus high genetic diversit
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Regulation of plant development through gibberellin signal transduction' under Fourth Framework.

assistant: **Concept**

Background and state of the Art: Gibberellins (GAs) are essential endogenous regulators that influence growth and development events throughout the life cycle of plants. Knowledge of GA signal transduction has advanced recently through research in a number of European labs and these are brought together in this proposal to form an internationally competitive and multi-disciplinary group to enhance knowledge of GA signal transduction and explore its use to develop novel methods of improving crop quality without the use of growth regulator chemicals. Objectives: Are described below and involve discovery and characterization of new genes and gene products involved in GA signal transduction. Work Package A: Identification and characterization of GA receptors and binding proteins Work Package B: Isolation and characterization of GA signal transduction components by molecular genetic approaches Work Package C: Unravelling GA regulation of gene expression during flowering and germination Work Package D: Examining the exploitation potential of the Arabidopsis dominant GA-insensitivity gene gai for modifying crop growth Industrial context: Agriculture, horticulture, citriculture and brewing industries, in Europe and world-wide, exploit the powerful growth regulating properties of GAs to enhance crop quality and efficiency. The partnership involves two industrial organizations that will contribute to three of the above work packages. This programme will advance understanding of the regulation of plant development through GA signal transduction, by identifying genes encoding components of signalling pathways and determining their function. The research will produce high-impact scientific publications and advance scientific and technical knowledge. It will interface strongly with a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Slow Photon Light Activated Switch' under Sixth Framework.

assistant: **Concept**

SPLASH addresses the issues of optical switches, tunable delay lines and optical buffering that is essential for realising the vision of all-optical data processing. The consortium will realise these functions by exploring optical slow light structures based on coupled ring resonators and photonic crystal waveguides. The core demonstrators are,a) Broadband slow light. Photonic crystal waveguides that combine sizeable slowdown factors with broad bandwidth and efficient optical coupling. b) Tunable coupler. By exploiting slow light phenomena in photonic crystals, the coupler will be very compact (10's of µm), yet require only refractive index changes of order 10-3 for complete switching. Tuning will be thermo-optic, electro-optic and all-optical.c) Tunable delay line. Tunable ring resonators will be used to continuosly control the delay properties of a system of coupled resonators.d) Switchable optical storage. By tuning/detuning the elements of a coupled resonator delay line, optical information will be stored.Structures will be realised in silicon on insulator technology to achieve the maximum compactness and maximum number of bits stored/unit area.