RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Larval Invertebrate Microalgal Interactions' under Sixth Framework.

assistant: **Concept**

This project will be carried out at SAMS, - Scottish Association of Marine Science, Dunstaffnage Marine Laboratory, Oban, Argyll, UK, from January 2004 to December 2004. The training part of the project will involve two aspects: study on intensive larval culture of the sea urchin. Paracentrotus lividus, and study on the impact of Amnesic Shellfish Poison (ASP) on king scallops reproductive physiology. Firstly, the training aspect is designed to familiarize the researcher with state-of-the-art instruments and methodology on sea urchin aquaculture research and Harmful Algal Bloom (HAB) studies that are being employed at SAMS. Secondly, the researcher will bring her competence in hatchery work of aquatic species from China, and improve the spectrum and excellence of the aquaculture research that is going on at SAMS. Incoming researcher's participation of research projects will include, mainly:1. Refinement of hatchery larval cultivation techniques of purple sea urchin, Paracentrotus lividus. Researcher will be responsible for larval cultivation, and will take part in the experiments on optimizing feed and environmental conditions for larval rearing.2. HAB study: influence of algal toxin on King Scallop, Pecten maximus. Researcher will participate in research on harmful effects of the ASP toxin on king scallop, to find out if carrying this phytotoxin will negatively affect scallops' gonad development, and if exposure to the ASP toxin has an adverse effect on scallop larvae. The incoming researcher will develop new, cutting-edge skills through this project, and will win better career prospects upon her return to China. Besides these, the opportunity of working in another country will raise the international profile of her career, and will enable her to participate in more jo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Classical Levitonics: transposing quantum levitons to classical waves for single side band wireless data transmissions' (C-Levitonics).

assistant: **Concept**

The project addresses the field of wireless digital communication. This field has constantly grown during the last twenty years with the development of cell phones and WiFi Local Area Network and with the development of digital TV broadcasting and satellite communications. A second expansion of digital communications has recently started with networks of objects: Bluetooth smart devices are available to consumers and RFID devices are used for object tagging, security identification and health sensors. Connecting devices will lead in a very near future to the Internet of Things. Digital communications form a huge market of 100 billion of transceivers connecting humans and devices. Any technological improvement is expected to generate important economic benefits. This is the aim of C-Levitonics. To physically encode binary information, wireless, optical fiber or copper wire data transmissions are based on the modulation of the phase or the amplitude of an electromagnetic wave, called carrier wave. A new waveform for the phase modulation associated with an elementary symbol (or bit) is proposed. It derives from a direct application to classical physics of the recently discovered levitons in quantum physics, a by-product of a former ERC AdG MeQuaNO project. The new modulation, called Single Side Band Phase Shift Keying (SSB-PSK), provides attractive spectral properties: single side band (SSB) spectrum (highly desired feature in optical or radio communications) and reduced frequency bandwidth allowing more users in a frequency range. Totally new (patent pending) SSB-PSK can operate using existing digital communication technology. A convincing demonstrator based on software radio technology will be delivered. In parallel a market prospective will identify the best markets and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Cold antiProtons for Better Antimatter Research'.

assistant: **Objectives**

The matter-antimatter asymmetry is a major unsolved problem in physics: Why do we live in a universe dominated by matter although physics tells us that equal amounts of matter and antimatter have been created at the Big Bang?The AEgIS project at CERN studies this problem by measurements of antihydrogen. Just last year, AEgIS achieved the pulsed formation of antihydrogen and enters now a new era of antimatter research, measuring the gravitational acceleration of antihydrogen and forming new, more complex antiprotonic atoms for spectroscopic investigation.However, the sensitivity of these measurements is limited by the thermal motion of antiprotons, in the case of pulsed formation of a neutral antihydrogen beam. The antiproton temperature could be lowered drastically by thermalization with laser-cooled ions. Laser-cooling, however, has never been realized with negative ions, as needed for cooling antiprotons, because almost no atomic anions do have strong optical transitions suitable for laser cooling.The goal of this project is to demonstrate laser cooling of the diatomic carbon anion – making it the first negative ion and the first molecular ion to be laser cooled. To reach this challenging goal, we will use an interdisciplinary approach, making use of the complementary backgrounds of the applicant (molecular physics) and the host (elementary particle physics).The impact of this project goes beyond antimatter research. Laser-cooled diatomic carbon anions can cool any other negative ion, thus enabling new experiments in atomic and molecular physics or physical chemistry. Furthermore, the transdisciplinary knowledge transfer between the host and the applicant, and the bridges built between atomic/molecular physics and antimatter research will lead to new research initiati
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'A detailed reconstruction of the early Milky Way from its most metal-poor stars'.

assistant: **Innovation**

The Gaia mission is providing many details on the dynamical complexity of our Galaxy, now and in the past. However, the picture of the Milky Way history becomes very incomplete at early times. The scarcity of well-studied early generations stars throughout different environments, represented by the lowest metallicity stars, limits us severely to study the era of First Stars and early Galaxy assembly. Next generation massively multiplexed instruments will soon complement Gaia astrometry to its faint limit with crucial radial velocities and chemical abundance patterns. Specifically, the Northern WEAVE and Southern 4MOST surveys will finally provide the high-priority targeting of the most metal-poor stars in low- and high-resolution needed.The aim of this EARLYMW ERC is to use these surveys to move the known history of our Galaxy back much farther to the first billion years after the Big Bang. I am in a unique position to make this step up from analysis of scarce individual stars to population studies, as I am leading the relevant very metal-poor target selection and survey efforts. To achieve the aim, my team and I will, after careful correction for selection effects (i) compare the chemical enrichment of early generations across Galactic components, and (ii) follow up very metal-poor tails of dynamical substructures and assess their dependence on progenitor properties. We will then compare our findings with cosmological simulations varying assumptions on early chemical enrichment.This EARLYMW project will, for the first time, provide a complete census of very metal-poor stars across various Milky Way components and quantitatively assess early enrichment processes as function of environment. Our results will constrain physical parameters for early Universe enrichment and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Biodegradable controlled drug delivery systems for the treatment of brain diseases' (BCDDS), addressing dissemination and exploitation.

assistant: **Impact**

The major objective of the present proposal is to develop new therapeutic strategies for the treatment of brain diseases. The aim is to restore, maintain and improve cell, tissue and organ functions within the Central Nervous System (CNS). Emphasis is on two kinds of diseases: brain cancer and neurodegenerative disorders, namely Parkinson ' s and Huntington ' s Disease. The treatment of CNS diseases is very difficult due to the Blood Brain Barrier, hindering most drugs to reach the brain tissue. Thus, target-specific delivery systems are required. Using a multi-disciplinary approach we will develop new pharmaceutical devices releasing highly potent drugs in a controlled manner into the CNS. The whole range of innovation, from advanced research, through technological development up to in vivo evaluation will be covered. With an industrial company in the consortium, also the economic exploitation of the outcoming scientific results is foreseen.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fifth Framework proposal on 'Educator Access to Services in the Electronic Landscape'.

assistant: **Concept**

EASEL will address the standards-based provision of online learning according to the learning community's requirements and exploiting state-of-the-art techniques using pedagogically adaptive content and question and test modules offering integrated student tracking throughout the learning experience. The construction of tried and tested interactive assessment modules is a costly process and thus collaborative effort, resource sharing and outsourcing this activity where appropriate should reduce costs to the educational institution, whilst also ensuring greater comparability between assessments being set across institutions.OBJECTIVESTo establish how learning objects exploiting the state-of-the-art in pedagogical adaptation can be integrated with the emerging Question and Test specification from the IEEE; To gauge the effectiveness and feasibility of utilising RDF/RDF Schema, BSR and the emerging Dublin Core v2.0 to support remote, cross-domain searching of online resources; To develop and test a course constructor kit, offering access to repositories both within and external to the institution by which educators can rapidly configure new course offerings from pre-authored materials, both using innovative pedagogy-rich resources (exploiting adaptive content and interactive assessment) as well as more traditional resources.DESCRIPTION OF WORK: The EASEL project will explore technologies which can be brought together to offer course constructors an environment in which they can readily combine existing learning objects to create new online educational offerings. This will necessitate access to: (1) Learning Object Repositories, both owned by the institution (or consortia of institutions) and available from third-party suppliers, (2) Predefined Assessment Banks, again both
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Critical State Soil Mechanics Revisited: Fabric Effects' (SOMEF) targeting Seventh Framework.

assistant: **Abstract**

The theory of Critical State Soil Mechanics (CSSM) has become a paradigm within the framework of which elastoplastic soil constitutive models have been developed for the last 50 years. The present project will constructively challenge this paradigm from a missing fundamental perspective, namely the effect of soil fabric on the premises of CSSM.The current CSSM postulates that at critical state the stress and void ratios reach critical values with no reference to orientational aspects of the soil fabric, such as particles long axes, contact normals or void vectors statistical orientations. Thus, several soil mechanical response characteristics associated with fabric anisotropy cannot be adequately or even correctly described within the existing theory. The hypothesis that an evolving soil fabric tensor must also acquire a critical value for critical state to occur will be investigated by theoretical, numerical and experimental means, including continuum and discrete elements methods (DEM) of analysis for cohesive and cohesionless soils, X-ray Computed Tomography studies on real soil samples, and triaxial, biaxial and hollow cylinder experiments. The results of this investigation will be used to propose a new enhanced CSSM theory with fabric playing a distinct role. Particular tasks will include the derivation of an objective rate equation of evolution of the fabric tensor, the formulation of classes of constitutive models for sands and clays within the new fabric-enhanced framework of CSSM, and the Finite Elements analysis of selected geomechanics boundary value problems illustrating the effect of soil fabric by comparing the results with and without fabric effects.Successful completion of this project will change the way Soil Mechanics is taught at Universities and appl
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'MICRObiome Biobanking (RI) Enabler' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

Microbiomes comprise communities of microorganisms (i.e., microbiota that includes bacteria, archaea, protists, fungi and microalgae) and their ""theatre of activity"" (i.e., structural elements, metabolites, signal molecules, mobile genetic elements, as well as surrounding environmental conditions). Microbiomes play a key role in maintaining life on Earth by providing a range of essential ecosystem services and are indispensable for the health of plants, animals and humans. Thus, there is a wide consensus that by harnessing microbiome functions society would be better placed to tackle global challenges such as food security, health and wellbeing, food waste management, and climate change mitigation. To facilitate the science necessary to achieve key advances in microbiome research, methodologies and technologies to capture or create, ensure stable long-term maintenance, and experimentally perturb microbiomes are required. Research infrastructures currently lack optimized methodologies and technologies to preserve and provide access to microbiome samples and massive amounts of associated data MICROBE is designed to address these issues by building upon and connecting: (1) technical solutions for microbiome preservation, propagation and functionality assessment, (2) novel ecological concepts (i.e. “core microbiome” and “microbial keystone taxa”), and (3) data infrastructures. In addition, MICROBE will address essential framework issues such as standardization, ethical and legal requirements and new business opportunities. Participation of relevant European research infrastructures, i.e., BBMRI-ERIC, MIRRI, ELIXIR and EMBRC-ERIC, to ensure that community needs are properly addressed and that developed solutions are efficiently taken up by the infrastructures themselves an
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Advanced Security-for-safety Assurance for Medical Device IoT' (MEDSECURANCE).

assistant: **Concept**

Advances in healthcare IT systems have resulted in complex socio-technical architectures, which deliver integrated and patient-centered services. All these transformations, in addition to clinical benefits, they also introduce risks including security risks that need to be understood and managed, reduced to acceptable levels. There are numerous reports of new types of security vulnerabilities for this kind of architectures, which challenge the effectiveness of the current security tools. MEDSECURANCE will conceive novel methodologies, infrastructures, and technologies that enable an effective, harmonious and continuous development and evolution of secure system engineering management activities in Internet of Medical Things (IoMT). Our objective is to advance knowledge and basic understanding of decision making in diverse IoMT threat landscapes based on different system and component level interactions. This is accomplished via the development of a novel holistic strategy that considers the interdependence of several IoMT subsystems, information exchange, risk thresholds, and regulatory ramifications. We provide scalable and verifiable secure system engineering management solution(s) that capture, communicate, and act on these complexities in order to improve decision-making in cyber defence while automating cybersecurity assurance. Our solution(s) will be co-developed and validated with our medical industry user partners, and complemented by engagement of healthcare industry stakeholders in support of the recommendations to existing guidelines that will also be developed in the project.


**Keywords:** IoMT, security, assurance, MDR
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Synthesis and antitumour activity of novel phenanthroline-containing bioconjugates - analogues for bleomycin activity', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

Research objectives and content Dr. Meunier's group in Toulouse have recently described the synthesis of Cu-bis-phenathroline-spermine bioconjugates as simple synthetic analogues for the antitumour agent Bleomycin. These species have been shown to cause degradation of plasmid DNA at nanomolar concentrations. The specific aims of this proposal are threefold: (1) preparation of a range of derivatives of this molecule in order to fine-tune the reactivity; (2) characterisation of metal complexes (specifically copper' of these ligands; (3) studies of the interaction of these complexes with DNA. Initial work in this project will involve systematic variation of the DNA binding domain of this molecule, through incorporation of minor-groove binders, intercalators and cell-attachment motifs. The pioneering work of Dervan will be used to incorporate oligo-N-methyl carboxamides as minor-groove binders. Modification of the electronic properties of the ligand binding domain are also envisaged, via incorporation of substituents at the 5 and 6 positions of the phenanthroline ligands. After characterisation of metal complexes, work will progress on to studying DNA interactions. Training content (objective, benefit and expected impact) The DNA aspect of this work will involve the greatest degree of training: Handling of plasmid DNA and preparation of restriction fragments, followed by reaction with novel bioconjugates is planned. I then plan to use this overall biochemical training in a research environment upon my return to the UK. Links with industry / industrial relevance (22)