RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'DEVELOPMENT OF NOVEL ASSESSMENTS FOR INDOOR AIR QUALITY MONITORING AND IMPACT ON CHILDREN'S HEALTH' to be submitted under Horizon Europe.

assistant: **Abstract**

LEARNing about the status of air quality in schools and its impact on the cognition of children is a major cornerstone in LEARN. For that, we want to overcome the barriers of the currently existing technologies and take a bold step towards the development and deployment of novel sensors to detect the presence of possibly harmful air pollutants such as volatile organic compounds and ultrafine particles. We will measure and characterize indoor and outdoor air pollutants and evaluate the presence of biomarkers of exposure and their effect on children´s cognition, while trying to recapitulate those effects using C.elegans as biosensor. Moreover, we will use advanced human-based in vitro models of lung and  skin coupled to a revolutionary multisensing device to investigate their mechanisms of toxicity in real-time.Novel remediation strategies will be explored to improve air quality and promote children´s quality of life and life expectancy. For that we will mobilize a group of eleven leading research teams, unrivalled in their respective fields (environmental epidemiologists, toxicologists, air quality specialists, systems biology, engineers and citizen/social scientists). The scientific achievements expected to result from LEARN will unlock a large technology potential in IAQ for decades to come, leading to disruptive societal and economic impacts steaming from a radical improvement in the quality of life of children in Europe.Project LEARN is part of the European cluster on indoor air quality and health.


**Keywords:** School cohorts, sensor, biomarkers of exposure, ultrafine particles, volatile organic compounds,organ-on-a-chip, biosensor, air filtration, public engagement
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'MEDICINE. Indigenous concepts of health and healing in Andean populations: understanding the relevance of traditional MEDICINE in a changing world.' under Horizon 2020.

assistant: **Concept**

In the context of a complex global agenda in traditional and complementary medicine, indigenous concepts of health and healing are less well documented and understood. MEDICINE will examine concepts of health and healing from an indigenous and culturally specific context, taking a unique time-depth perspective and with a framework of interdisciplinary methods which integrates archaeological-historical, ethnographic and modern health sciences approaches. MEDICINE offers a novel perspective and methods in the development policies sensitive to indigenous and minority people’s social, economic and health needs and, too, on developing culturally sensitive approaches to the conservation of their ‘intangible cultural heritage’. MEDICINE will also develop novel methodological and theoretical approaches to model how peoples survive and adapt their traditional belief systems in a context of alien cultural impacts. The study population are indigenous Quichua peoples in the northern Andean region of Ecuador, a country where the ER has considerable experience. Models of their understanding of health, illness and healing, and the way these have adapted and changed through time will be used to develop a ‘tool’ transferable to contemporary global policy scenarios.MEDICINE will benefit from the ER's unique perspectives from Medicine and Archaeology to explore the impact of traumatic cultural transition on people, the significance of traditional practices as intangible cultural heritage, and the degree to which the longer-term archaeological perspective can help promote understanding in a vital area of contemporary concern. It will enable her to develop further policy relevant skills, a particular output being contributions to policy and practice in the development of culturally sensitiv
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Amyloid imaging to Prevent Alzheimer’s Disease – Sofia ref.: 115952' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Beta-amyloid (β-amyloid) deposition is considered to be a necessary - but not sufficient - step on the path towards Alzheimer’s disease (AD). Depiction of brain β-amyloid in vivo can support an early diagnosis, and even provide an opportunity for consider secondary prevention of AD. Currently, however, the value of β-amyloid PET remains elusive, reason why this procedure is typically not reimbursed.Understanding the value of imaging of β-amyloid using positron emission tomography (PET) provides a unique opportunity to achieve 3 major goals: 1) improve the diagnostic workup of patients suspected of AD and their management; 2) stratify risk for AD and select homogenous groups for intervention; and 3) quantify treatment effects more accurately.AMYPAD will address the above objectives by studying the onset, dynamics, and clinical relevance of brain β-amyloidin the spectrum from normal aging to preclinical and prodromal AD. We will use β-amyloid-PET in an unprecedented large number of subjects (n=4000) from population studies, as well as memory clinics cohorts, with repeat imaging in up to 2000. In close collaboration with EPAD (www.ep-ad.org), the cohorts will be followed with to determine (surrogate) outcomes of cognitive decline and neurodegeneration.Lead from VU-VUmc, the Consortium brings together a word-class team of highly synergistic partners from across Europe constituting a highly experienced and efficient β-amyloid imaging network including the most active European PET sites, to ensure effective tracer delivery, access to patients and expertise to technical knowledge and disease modelling.AMYPAD will establish the true value of β-amyloid PET across the severity range of AD. Patients and clinicians will benefit from better and cost-effective diagnostic procedures a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'NightWatch - Clinically-proven detection and alert system for critical nocturnal epileptic seizures.' in the context of a Horizon 2020 call.

assistant: **Objectives**

More than 50M people worldwide suffer from epilepsy, characterized by uncontrolled seizures, and about 30% find no relief from those despite taking medication. Nocturnal seizures can be critical; each year at least 33.000 people in EU die of Sudden Unexpected Death in Epilepsy (SUDEP), 40% of which could be prevented by attending the seizures on time. This is a continuous challenge for patients and caregivers, with important social and societal consequences (anxiety, depression, lack of sleep), and high intramural care costs (over €20 billion per year in EU).The NightWatch is a registered medical device that detects and notifies wirelessly remote caregivers in case of heavy nocturnal seizures in just few seconds. The bracelet uses a combination of heart rate and movement measurement, a unique AI algorithm conceived by three Dutch institutes specialised in epilepsy, automatically adapting to different patient patterns to minimize false alarm rate. It has been clinically tested and can detect > 90% of all types of urgent nocturnal seizures making it the most reliable system available.The NightWatch targets caregivers, patients and professionals who seek an effective alarm system for severe nocturnal seizures. It improves their quality of life giving them peace of mind, higher level of independency, reduces cost of care by reducing the need for intramural attention, and prevents deaths caused by SUDEP. With a trend to-wards home care and self-monitoring pushing market growth (expected to reach €4.0 billion in 2019), wearables becoming the preferred type of seizure monitoring. EU leads the seizure monitor devices market (46%), followed by North America (28%).NightWatch is the flagship product of LivAssured, a Dutch company created in 2013 as a spin-off to take over the comm
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Sixth Framework proposal on 'Study of the oversolubility of gases in liquids of nanometric volume'.

assistant: **Innovation**

This project deals with the study of a basic phenomenon: the solubility of gases in liquids, which has many implications in physics, chemistry and engineering. What makes this proposal original is the nanometric scale of the system studied. Goals The main objective of this project is to understand why recent solubility measurements, on nanometer-scale gas/liquid systems, show values much higher than in a macroscopic bulk: what we called the oversolubility effect. A second objective is to build up a predictive model of the effect, as a function of the nature of the gas, the solvent, and the system size. A third objective deals with the search of possible applications of this effect, particularly for gas storage (hydrogen, carbon dioxide). Expected results Apa rt from the above model, the main expected results are quantitative data of the nano-scale oversolubility effect, for as much gas / liquid systems as possible. The results will be obtained as a function of temperature, gas pressure, and solvent volume size . We will focus on general interest systems in process engineering, such as H2, O2, N2, and gaseous hydrocarbons in liquid hydrocarbons and water. Special attention will be given to systems including CO2 as a gas, due to its importance in the current globa l warming, and to those including H2, for its potential use as energy source. If the results are favourable, first tests of storage applications for these two gases will be considered. Methodology Three measurement methods will be used: - Quantitative NMR. - Micro-catharometric analysis. This device will be set up together with a high throughput feed and acquisition unit. - Micro-volumetric studies, based on very precise pressure sensors and temperature cycles. For modelling studies, the hypothesis of a pure ly
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Superconducting magnetic-field compatible quantum electronics' to be submitted under Horizon 2020.

assistant: **Abstract**

In superconducting quantum electronics, or superquantronics, macroscopic degrees of freedom, like currents and voltages, can exist in a quantum mechanical superposition. This macroscopic quantum coherence has led to the development of circuits behaving as atoms. An exciting new field of research is circuit-based quantum electrodynamics (cQED), in which these artificial atoms are placed in cavities to perform quantum optics in the microwave regime. This cQED architecture is arguably the most promising platform for realizing a full-scale quantum computer. However, a major draw-back of the circuits used for cQED today, which contain aluminum films, is that superconductivity is lost upon applying strong magnetic fields. This limitation poses a fundamental obstacle to interfacing superquantronic circuits with other quantum systems that rely on these strong magnetic fields for their operation. By forming such hybrid systems, new technologies can be developed, such as long term quantum memories for superconducting qubits using highly coherent solid-state spin ensembles, or a topological quantum computer using Majorana Fermions.The goal of this proposal is to realize magnetic-field compatible superquantronic circuits for the cQED architecture.A promising new approach is to combine magnetic-field compatible superconducting materials with semiconducting nanowires to build new circuit elements. We plan to develop circuits using these new elements and demonstrate the coherent operation of an artificial atom in cQED in the presence of a strong magnetic field. The magnetic-field compatible superquantronic circuits we will develop, provide a unique platform to create and study new quantum devices. This fellowship, along with his previous research experience with a wide range of quantu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Advanced Transformation Optical Materials for bio-Imaging and light-Concentration' (ATOMIC), addressing dissemination and exploitation.

assistant: **Impact**

With the dramatic advances in micro- and nano-fabrication methods, we are presented with the opportunity to control light in a way that was not possible with the materials provided to us by nature. In an artificial pattern of sub-wavelength elements, the propagation of electromagnetic energy can be defined by an equivalent spatial and spectral dispersion of effective dielectric and magnetic properties. Transformation optics (TO) is a new paradigm for the science of light, which is enabled by recent developments in our fabrication capabilities with respect to metamaterial-based devices. TO is based on the invariance of Maxwell’s equations with respect to coordinate transformations, provided that the basic optical parameters of materials, dielectric permittivity ε(r) and magnetic permeability µ(r), are also transformed appropriately. This makes possible molding and controlling light on all scales, from macroscopic sizes down to the deeply sub-wavelength scale. My project aims to study the fundamentals of the emerging area of TO through the use of novel metamaterial-based devices. These photonic elements hold the promise for establishing new paradigms in integrated photonics by enabling an unprecedented control of light. We will develop both the simulation tools and the fabrication processes for creating a new-generation of planar magnifying hyperlenses and light concentrators. While the first components are fundamentally useful in order to image below the diffraction limit, the latter can be revolutionary for boosting photovoltaic cell efficiency. Following these goals, during the last part of our experimental campaign, our devices will be incorporated in two home-made set-ups; one for the evaluation of the photo-electric efficiency, and the second for the imaging of biol
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'GET: Global E-health Transforming services'.

assistant: **Innovation**

The GET project will deliver four high-impact services to eHealth SMEs and entrepreneurs in order to boost their growth and move them to the next level of competitiveness. Each life-transforming service has been designed to provide cross-border value to a different target group of companies. It will do by offering training, mentoring, market intelligence, support and, above all, quality contacts.<br/>These services are:\tGet on track: Targets early-stage companies, start-ups and entrepreneurs. It supports them to optimize their business model and commercialization strategy.\tGet funded: Designed for SMEs looking for a second round of funding. It provides training, resources and networking opportunities with investors at European level.\tGet global: Helps mature SMEs to access international markets by putting them in contact with foreign commercialization partners and potential customers.\tFill the gap: Bridges between healthcare purchasers with ´market gaps´ and SMEs with the required technological skills.<br/>They have been designed to maximize direct impact to targeted beneficiaries, but without overlapping with business-development support offered by other organizations at regional or national level.<br/>The two key differentiators with the current offer are:\tMarket-centric. Because the services will be offered to companies operating in one concrete market -Information Technology for Healthcare-, all the resources and applied expertise (both from organizers and stakeholders) will be of immediate actionable value.\tCross-border. The 4 services have been designed with an international vision from the start. They will be delivered after a pan-European selection of the best of breed, with the support of advisors from multiple nationalities. As a result, cross-bord
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Advanced materials for lean burn combustion tiles using laser-Additive Layer Manufacturing (L-ALM)' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

The objective of this project is to develop materials and processes for use in laser additive layer manufacture, which are capable of meeting the stated requirement for advanced, high temperature  nickel superalloys (with high levels of gamma prime forming elements) for use in novel combustion components for lean burn engine developments.The Participants will review the current state of the art and determine a shortlist of three potential alloys for development. In collaboration with the Topic Manager, one alloy will be selected for development. A representative application for the selected alloy will be defined and appropriate specifications determined for geometrical accuracy, surface finish and materials properties.The first phase of experimental work will develop a Additive Layer Manufacturing process, optimised for the properties determined above. In a second phase, this 'best known' method of manufacture will be used to manufacture multiple batches of part geometries and test specimens in order to provide sufficient statistical confidence in the data to allow use of this process for the manufacture of parts for use in an engine-realistic environment.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'New Histories of British Moral Philosophy in the Eighteenth Century (c. 1690–1800)' under Horizon Europe.

assistant: **Concept**

Women continue to be excluded and marginalized in histories of eighteenth-century British moral philosophy. BMoral addresses this by advancing a novel transdisciplinary methodology that brings together philosophical methods of close reading and interpretation with recent computational methods used by digital humanities researchers. Research on women philosophers has often focused on individual figures. BMoral’s new approach moves beyond the study of individual women philosophers and analyses intellectual networks with the goal of gaining a deeper understanding of how male and female philosophers interacted and influenced each other’s writings. Further, it offers unprecedented opportunities to analyse and assess the extent of women’s distinct contributions to moral philosophy and to recover neglected themes in the corpus of 18th-century moral writings.The overall research question is: How can women and their philosophical contributions as well as unduly neglected male philosophers be better integrated into histories of 18th-century British moral philosophy? To address this question, BMoral pursues three objectives, which aim to analyse and assess (1) how male and female philosophers approach not only theoretical moral issues, which have been the main focus of recent scholarship, but also practical moral issues; (2) women’s unique contributions and their role in 18th-century intellectual networks; (3) what themes have been neglected or understudied. BMoral will deliver ground-breaking results by (i) conceptually shifting the focus of 18th-century British moral philosophy towards practical lived experience; (ii) recovering and reassessing 18th-century intellectual networks; (iii) analysing a large corpus. These results have the potential to achieve lasting breakthroughs, f
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Role of gtpases of the rho family in the control of phagocytosis' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

The objective of this project is to study the role of GTPases of the Rho subfamily during phagocytosis in macrophages Interaction of microorganisms with cell surface receptors initiates signalling pathways, leading to submembraneous actin assembly and ingestion of the particle. Rho, Rac and Cdc42 are involved in the control of various cellular processes dependent on actin polymerization. First, We shall analyse the effect of inactivating these proteins on phagocytosis of IgG-coated particles. Next, using transfection and microinjection techniques we shall define how Rho, Rac and Cdc42 control signalling pathways linking ligation of Fc*R or CR3 to actin polymerization during phagocytosis in COS cells and U937 derived macrophages. Finally, we shall analyse the molecular pathways activated upon interaction between macrophages and different bacterial pathogens. These studies may allow us to identify intracellular targets for virulence factors of Yersinia spp. for example, which are able to impair actin polymerization and inhibit their uptake.