RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Fostering Improved Training Tools For Responsible Research and Innovation' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

FIT4RRI moves from the assumption that there is a serious gap between the potential role Responsible Research and innovation (RRI) and Open Science (OS) could play in helping Research Funding and Performing Organisations (RFPOs) to manage the rapid transformation processes affecting science (especially the science-in-society aspects) and the actual impact RRI and OS are currently having on RFPOs, research sectors and national research systems. FIT4RRI is precisely intended to contribute in bridging this gap, promoting viable strategies to activate institutional changes in RFPOs. The project, in particular, will act on two key factors i.e.  i) Enhancing competences and skills related to RRI and OS through an improvement of the RRI and OS training offer (in terms of training tools, actions and  strategies) presently available; ii) Institutionally embedding RRI/OS practices and approaches by promoting the diffusion of more advanced governance settings able to create an enabling environment for RRI and OS. With this double aim in view, FIT4RRI is organised following an overall methodology based on three main steps: an analytical strand devoted to understand  what is happening in the RRI and OS practice, taking into account general trends, barriers and drivers to RRI and OS, interests and values, advanced experiences; a  testing strand (observing RRI/OS in action though 4 co-creation experiments) aimed at figuring out possible solutions  in terms of training approaches and governance settings; and a proactive strand, promoting changes (i.e. developing training tools and actions and easy-accessible evidence-based guidelines on governance settings functioning as enablers for RRI and OS). The project will last  36 months  and  includes  7 WPs: Mapping and benchmarking; Sectoral
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Performance analysis of road infrastructure' demonstrating excellence, impact and implementation quality for a Fourth Framework call.

assistant: **Abstract**

Data acquisition on test sections throughout Europe and analysis of the data to yield pavement performance models.The PARIS project will provide a data base of the in-service performance of European road test sections, gathered in so-called Real Time Loading Testing (RLT). These data will be extended with information obtained from Accelerated Loading Testing (ALT) of pavement sections using dedicated research facilities. Ultimately, the PARIS project will give road managers the tools needed for cost-effective management of the European road infrastructure.The following measurable objectives are identified:- Uniform definitions, data acquisition systems and analysis methods to interpret road pavement performance.- A central research database for road condition data gathered in the participating countries.- A coherent set of pavement performance models, applicable for different conditions, climates and materials. These models will be based on real-time data from all participating countries and additional data from accelerated loading tests.- Verification of the pavement performance models developed.- Suggestions for implementation of the models.- Coordinate the project with other related activities. %
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'A combined approach of cryo-electron tomography and protein tagging for elucidating the structural organization of the human Nuclear Pore Complex' to be submitted under Seventh Framework.

assistant: **Abstract**

Nuclear Pore Complexes (NPCs) represent the exclusive passageway in and out of the nucleus but also function in gene regulation and nuclear organization. NPCs serve as docking sites for many viruses and were associated with several human diseases, e.g. leukemia. Understanding the nuclear transport mechanism will have a huge impact on human health research of such diseases. Multiple copies of ~30 different protein components, termed nucleoporins (Nups), form the major building blocks of NPC. Nups are organized as repetitive modules, called subcomplexes. The subcomplexes, in turn, form the scaffold of NPC in an unknown arrangement. Despite their importance, structure determination of NPCs is a considerable challenge, primarily due to their sheer size.To generate an atomic model of the human NPC, data at the different resolution levels have to be systematically collected and integrated. Determining the position of Nup subcomplexes within the NPC will be a critical step to bridge the resolution gap between different structural techniques. Since the precision of 2D-immuno-gold labeling techniques is insufficient to associate individual Nups with distinct features of the NPC structure from cryo-electron tomography (cryo-ET), alternative strategies are needed to achieve this goal. Here I propose to improve the resolution of the human NPC structure to allow assigning subcomplexes into the overall assembly. This will be achieved by cryo-ET, subtomogram averaging and further development of algorithms correcting for NPC plasticity. Furthermore, I will determine the precise positioning of subcomplexes by obtaining 3D structures of NPCs containing tagged Nups. This will contribute significantly to our understanding of the overall organization of the NPC and thus, nuclear tranport me
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Phenological observations and satellite data (ndvi): trends in the vegetation cycle in europe' under Fifth Framework.

assistant: **Concept**

Problem to be solvedExploiting existing datasets to monitor and understand links between seasonal plant and animal activity and climate change.Objectives and approachThe POSITIVE objectives are: to develop and test autumn phenological models; to test springtime models found to be effective on a regional scale; to fit a new unified model for European temperate tree species; to develop a new pollen shedding model for the main allergenic taxa in different European regions; to study phenological shifts and changed gradients in the Alps as well as to describe the geographical and temporal variability and trends of phenological phases in Europe (1951-1998); to analyse the temporal and spatial variability of the green wave in Europe; to quantify large-scale growing season duration for the northern hemisphere and to determine changes in the photosynthetic capacity. POSITIVE will create and integrate a common phenological data set of key species and phases, suitable to study the temporal and spatial variability of phenophases in Europe, comprising observations of the International Phenological Gardens, the national phenological networks of the German, Swiss, Austrian, Estonian weather services and other new phenological data from Post Soviet States as well as data out of the European pollen network. POSITIVE will produce a new 1981-2000 satellite data set for the entire level-1b 4km global data record from the AVHRR instruments flown on the NOAAA-7, NOAAA-9, NOAAA-11, and NOAAA-14 satellites, post-processing review of the data will be undertaken to insure the correction of different artefacts. Using these data POSITIVE will study, by statistical analyses, phenological shifts and gradients in the Alps, phenological trends of the last 4 decades in Europe, especially the duration o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Bacterial Persistence' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

Almost all bacterial species generate persisters, individual cells that are tolerant to antibiotics. Persisters have entered a dormant or slow growing state in which they are recalcitrant to the killing activity of most known antibiotics. The molecular mechanisms underlying bacterial persistence are unknown and there is a pressing need to develop new methods and approaches to study the phenomenon. We discovered recently that RNA endonucleases (RNases) encoded by toxin - antitoxin (TA) genes are required for persistence of the model bacterium Escherichia coli. We have shown that the RNases inhibit translation by cleavage of mRNA or tRNA and that their activation halts cell growth and induces persistence. We propose a testable model in which persistence is induced by stochastic activation of the RNases. Almost all free-living bacteria, including many serious pathogens, have TA genes, often in multiple or even many copies. For example, the major pathogen Mycobacterium tuberculosis, which can persist in the human body for many years, has at least 88 TA loci. This proposal describes a research program dedicated to develop novel general methods to study the persistence phenomenon and to test the hypothesis that TA loci are central to bacterial persistence. The implementation of novel, leading edge technologies will allow a profound understanding of the persistence phenomenon. Mechanistic insight into the persistence problem, in turn, will provide a basis for a rational approach to the development of drugs and drug administration regimes that may improve treatment of persistent infections.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Smart miniature low-power wireless microsystem for Body Area Networks' (WiserBAN).

assistant: **Concept**

The WiserBAN project will create an ultra-miniature and ultra low-power RF microsystem for wireless Body Area Networks (BAN) targeting primarily wearable and implanted devices for healthcare, biomedical and lifestyle applications.The proposed research concerns the extreme miniaturization of the BAN with primarily the areas of ultra low-power radio SoC (System on Chip), RF and Low-frequency MEMS, miniature reconfigurable antennas, miniaturized SiP (System in Package), sensor signal processing and flexible communication protocols.The WiserBAN microsystem will be 50 times smaller than today's radio modules for Personal Area Networks (PAN) solutions, e.g. Bluetooth, that can simply not be embedded in a variety of tiny implants and wearable applications. WiserBAN will thus enable significant take up by the European SME's and industries in healthcare, bio-medical and lifestyle.WiserBAN will also create a major impact on the quality of life of the European Citizens, in particular for improving the comfort and access to ICT for impaired and disabled people of all ages carrying implants or wearing medical devices, hence reducing the risk of social exclusion.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Resource rEcovery FRom novel Assisted MEtabolism' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

The new policies issued by the European Commission support the concept of bioeconomy and circular economy to develop a new value chain in the market across the implementation of innovative technologies for the production of bio-based compounds from (bio)waste and wastewater. In this scenario, REFRAME project aims to upgrade wastewater treatment plants (WWTP) into Water Resource Recovery Facilities (WRRF) in which wastewater and sewage sludge are used as raw materials for the production of different bio-based compounds. A bio-based compound is defined as a product that is derived from materials of biological origin. The main objective of REFRAME is to develop a new hybrid biological system assisted by an oxidation-reduction potential (ORP) based control for the combined production and purification processes of targeted bio-based volatile fatty acids (VFAs) and polyhydroxyalkanoates (PHAs). REFRAME will be the platform for chemicals, precursors for bioplastics, and feed ingredients ready for the market. A WWTP becomes a WRRF that attempts to produce valuable and marketable bio-based products, such as cellulose by utilizing the organic matter from the wastewater as raw material. The recovery of cellulosic primary sludge (CPS) could be biologically converted to other bio-based compounds, such as VFAs and PHAs. The project will advance the state of the art of the field by the investigation of a new type of bioprocess and bacterial metabolisms to fill the current lack of the long-term stability, quality, and purity of isolated bio-based compounds (VFAs and PHAs) produced from CPS as raw materials.The applicant has a proven record of biological processes control, a fundamental skill required for REFRAME. He will thrive in the environment of the University of Verona, department
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Rogue waves - forecast and impact on marine structures (MAXWAVE)' under Fifth Framework.

assistant: **Concept**

Within the last years a high number of large ships has been lost. The causes of accidents are in many cases believed to be 'rogue waves'. These are individual waves of exceptional wave height or abnormal shape. In these project properties and forecasting abilities for low frequency wave fields, extreme individual waves and wave groups are investigated for both deep and shallow waters. New design criteria considering the impact of rogue waves on ships and offshore constructions will be derived. The innovation is the combination of new oceanographic knowledge and ocean wave data resources with new approaches to vessels, marine construction, design and operation. It addresses the needs of coastal engineers and port designers/operators in terms of influence and impacts of extreme waves. The main objective is to provide a quality-based metocean information product for the benefit of both high sea and coastal zone operating industry and authorities.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Investigate for cellular partners of DPP6 and DPP10 through novel technologies' demonstrating excellence, impact and implementation quality for a Sixth Framework call.

assistant: **Abstract**

Potassium channels contribute to the control of cell volume, membrane potential, neuronal excitability, and the secretion of salts, hormones and neurotransmitters. Their activities are regulated by a number of factors including the electrical potential across the cell membrane, cytosolic calcium and ATP and by the action of various kinases/phosphatases and other accessory proteins. It has been recently shown that two members of an ecto-peptidase family, DPP6 and DPP10, whose function was previously unknown, may interact with some voltage-gated channels of the Kv4 family and affect their properties, through a mechanism still unknown.This project is focussed on the elucidation of the physiological role of DPP6 and DPP10 through the identification of their bin ding partners (included putative substrate proteins) and characterization of their structure-function relationships. These data will be useful for the development of inhibitory molecules for pharmacological or therapeutic use. In order to achieve this result we propose an innovative and interdisciplinary approach, based on novel HTS selection of interacting partners.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Sixth Framework proposal on 'Polymer surface modification by ion implantation'.

assistant: **Concept**

It has been demonstrated that ion implantation can effectively modify the surface properties ofpolymers by scission and cross-linking of the high-molecular weight molecules within the material.Advantageous bulk properties such as low-weight, ease of formab ility and relatively low cost can bemaintained whilst surface properties such as biocompatibility, hardness, optical properties and electricalconductivity are improved. The aim of this project is to utilize the facilities and expertise at theForschungszent rum Rossendorf (FZR) to modify the surface properties of polymers commonly used forbiomédical purposes. Control of the surface wettability and roughness, gas permeability, scratchresistance, the degree of carbonization, and the stimulation of surface chemi cal reactions by scission ofsurface bonds will be explored. Additionally, changes in biocompatibility by the deposition of ultra-thinfilms of known biocompatible and bio-stimulating, and also bio-inhibiting materials will beinvestigated. Analysis of the bi ocompatibility of the modified surfaces will be undertaken and themechanisms for surface modifications promoting improved biocompatibility will be investigated.Application of the plasma immersion ion implantation technique to impart observed improvements t ocomplex shaped objects, such as are commonly found in biomédical applications, will be undertaken.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Targetry developments for the third generation of Radioactive Ion Beams facilities' under Sixth Framework.

assistant: **Concept**

The objectives of this proposal are the research, design and manufacture of fast-release target-ion source assemblies for the on-line production of radioactive ion beams, possibly allowing access to shorter-lived nuclides and increasing the intensities of the existing beams.This will be achieved by:1) systematic off-line and on-line investigation for promising target material/product species systems, complementing the TARGISOL database of their release properties and indicating correlations between materials with alike chemical or structural properties or diffusing species in the same chemical group;2) shaping of the target material in order to be employed at the various European ISOL RIBs facilities;3) research and design of prospective high-temperature electrolytic targets, a class of materials showing super-ionic conductivity.The research techniques employed will be ion implantation followed by off-line release measurements with and without an applied electric field. This will be complemented by the o ff-line thermochromatography and by the on-line measurements of the yields and delay curves. The proposed Host Institution is the world-leading ISOL facility CERN-ISOLDE: with a long-standing tradition of over 30 years in the production of radioactive ion beams, it represents the perfect scientific context for a close and continuous interaction with other scientists and technicians very skilled in the topic.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Sail PLAn service for energy efficient SHipping (SPLASH) - innovative and revolutionary sail planning' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Shipping and offshore are in great need for energy efficient methods, whereby optimised voyage planning and weather routing are among the two most well-known. The main challenge today is that while there are several prospective and useful solutions out there, a uniform or standardised procedure to evaluate fuel and emission gain or loss by implementing one or another solution is lacking. Consequently, it is impossible for a ship owner/operator/charterer to know if a vessel saves more fuel or reduce more emissions by integrating solution X or solution Y. This in turn impedes the industry's ability to adapt their operations to become more environmentally friendly as well as more efficient. It also hinders new innovations (such as the results of several EU projects referenced within this proposal) to successfully be absorbed or bought by the industry. The primary project objective is to conduct a feasibility study of a generic fuel consumption module (FCM) that accurately estimate fuel consumption burning rate of any ship under various environmental conditions. It will evaluate if one fuel/emission saving solution is more favourable than another.The FCM can be integrated into an existing sail plan service for routing optimisation based on already established weather module inputs. The final objective is to prepare a business plan for the commercialisation of the ‘standalone’ FCM as well as the integrated sail plan service containing the FCM.