RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Creation of the mediterranean link committe on the processing tomato research' (MELCOPTOR).

assistant: **Concept**

Taking the unique opportunity of an ISHS Symposium in June 2002 in Istanbul (Turkey), AMITOM expects to create and structure a Link Research Committee on the processing tomato industry research in the Mediterranean region. This link Committee requires a critical mass of expertise throughout a broad spectrum of disciplines from seeds breeding to human nutrition, including industrial processing, crop physiology, agronomy, fertile-irrigation management , weed, pest and disease control.... The coordinator asks for the European financial support for organizing the attendance of at least 20 non-European Mediterranean Institutes who could so present their up-dated works and get in touch with the European Research. The mutual benefit of such link committee for all the mediterranean basin is clearly demonstrated in the proposal.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Labelling biodegradable products' will create measurable scientific, societal and economic impact aligned with Fourth Framework.

assistant: **Impact**

The main objectives of this project is are development of guidelines, testing scheme and predictive models for labelling biodegradability of (agro) industrial polymers in relation to their environmental fate in agriculture and waste treatment. In order to rearch these objectives, the following specific objectives and tasks are assigned (a) To obtain better knowledge of available and recently developed so-called biodegradable" materials, including environmental fate and  characterization methods. (b) To determine the degree and rate of biodegradation and environmental safety of different biodegradable materials (e.g. starch based, polysters, etc.) using laboratory tests, including test development/improvement if necessary. (c) To determine the degree and rate of "real-time biodegradation" and environmental safety of different biodegradable materials in practical relevant environments -either agricultural or composting ones. (d) To determine and model the correlation of biodegration data from standard laboratory tests and "real-time" biodegradation experiments. (e) To develop predictive models for a fast and economical acceptable pre-evaluation of biodegradability of materials for use in industrial development of new biodegradable products. (f) To develop guidelines for labelling biodegradability of polymeric materials in relation to their environmental fate in agriculture and waste treatment. For this project, a multidisciplinary consortium has been created including scientits (agriculture and polymer science), marketing sectors (material development and waste treatment industrles), and legislators (participants of national and European standardization committees concerning packaging and biodegradability) in order to define the market viability of new biodegradable produ
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Ultra-stable, highly efficient, low-cost perovskite photovoltaics with minimised environmental impact' under Horizon Europe.

assistant: **Concept**

The decarbonization of the energy sector to mitigate climate change is a key challenge for the European Union (EU). This mandates a rapid and widespread implementation of a clean and affordable energy infrastructure in which photovoltaics (PV) will be a main pillar. Currently, PV represents only a small fraction of the global energy supply and PV modules are almost exclusively imported from outside the EU, associated with supply risks and a high CO2-footprint. Emerging perovskite PV has a tremendous potential to overcome these issues and revolutionise the EU energy sector. To unfold this potential, the DIAMOND project joins 6 European leading universities (UGroningen, UUppsala, EPFL, URome-TV, UPorto, UMarburg), 2 research institutes (Fraunhofer ISE, CEA) and 4 industry partners (Dyenamo, BeDimensional, Solaronix, PixelVoltaic) from 7 different countries to develop ultra-stable, highly-efficient and low-cost perovskite PV with minimised environmental impact. To achieve stabilities far beyond all previous achievements of PV solar cells, the project targets to develop novel hermetic encapsulation approaches and highly stable device designs that are evaluated by standardized and novel stability assessment methods. DIAMOND also aims to optimise materials and cell stacks to reach efficiencies exceeding the record values of silicon PV. Fully printable module architectures are targeted for rapid industrial up-scaling, allowing for lowest manufacturing costs and local production in the EU. To minimise the ecological impact, specific device designs that enable lowest CO2-footprint, material criticality and toxicity together with enhanced recyclability are targeted. Combining these ambitions, DIAMOND strives to provide a strong impact on the EU’s future environmental, economic an
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Magnetically Actuated Stents: Enhancing Precision and Control in Vascular Interventions using Superparamagnetic Hydrogels Composites' (MagStents), addressing dissemination and exploitation.

assistant: **Impact**

Cardiovascular diseases represent a critical global health challenge, affecting millions through the obstruction of blood vessels. Existing interventions, particularly conventional stents, are hindered by significant limitations such as rigidity and a high risk of restenosis. This proposal introduces MagStents, an innovative fusion of soft polymers and magnetic nanoparticles, designed to overcome these challenges. While traditional metal stents restore blood flow, they are constrained by inflexibility and potential vessel damage. In contrast, MagStents offer a biocompatible, flexible, and self-expanding alternative, constructed from dual crosslinked hydrogels.A key advancement of MagStents is their magnetic actuation, enabling precise positioning, adjustment, and post-deployment control using an external magnetic field. This capability introduces a novel dimension in cardiovascular intervention, reducing the need for surgical procedures by allowing real-time non-invasive adjustments.The research will focus on the development of Magnetic hydrogels (MagGels), engineered with controlled magnetic and mechanical properties. Advanced additive manufacturing technique will be employed to fabricate MagStents that incorporate these MagGels, ensuring both structural integrity and magnetic responsiveness. Comprehensive evaluations will assess biocompatibility, mechanical performance, and magnetic behavior, alongside the potential for controlled drug release in vitro.MagStents offer a significant advancement in interventional cardiology by enabling remote, non-invasive manipulation and enhanced adaptability. The research aims to establish a new standard for stent performance, improving patient outcomes and addressing the current limitations of cardiovascular disease treatments. Thro
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Protocols and Strategies for extending the useful Life of major capital investments and Large Industrial Equipment'.

assistant: **Concept**

Europe is still lacking an efficient systemic multi-level approach that enables a recursive, cost-effective, holistic and integrated application of circular principles to the digital uplifting of factory 4.0 capital investments; addressing issues at product, process, system as well as the entire value-chain levels, integrating best practices from emerging enabling digital technologies and avoid a two speed digital transformation across industries in different sectors. LEVEL-UP will offer a scalable platform covering the overall lifecycle, ranging from the digital twins setup, modernisation actions to diagnose and predict the operation of physical assets, to the refurbishment and remanufacturing activities towards end of life. In-situ repair technologies and the redesign for new upgraded components will be facilitated through virtual simulations for increased performance and lifetime. LEVEL-UP will therefore comprise new hardware and software components interfaced with the current facilities through IoT and data-management platforms, while being orchestrated through eight (8) scalable strategies at component, work-station and shopfloor level. The actions for modernising, upgrading, refurbishing, remanufacturing, and recycling will be structured and formalised into ten (10) special Protocols, linked with an Industrial Digital Thread weaving a seamless digital integration with all actors in the value chain for improved future iterations. LEVEL-UP will be demonstrated in 7 demo sites from different sectors. The impact of LEVEL-UP to the European manufacturing industry, but also the society itself, can be sum-marised in the following (with a horizon of 4 years after project ends): (i) increase of the material and re-source efficiency by 11.5%, (ii) increased reliability by 1
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Producing novel non-plant biomass feedstocks and bio-based products through upcycling and the cascading use of brewery side-streams' (CHEERS) under Horizon Europe.

assistant: **Objectives**

Biotechnology has the potential to reduce the impact of human activities in nature. By developing new bio-based production platforms towards a more efficient use of waste streams, a step forward in industrial circularity can be achieved. CHEERS is a new biorefinery concept, inspired on nature biodiversity (insect and microbial platforms), to sustainably and efficiently upgrade underused or waste side-streams such as bagasse, wastewater, CO2 and CH4 from bio-based industries into innovative bio-based products. CHEERS will help bio-based industries to improve their feedstock use efficiency and overall sustainability and competitiveness via upcycling and cascading use of biomass produced from their side-streams. CHEERS is developed as a modular solution where bio-based industries can configure their optimal combination by selecting among 5 novel biotechnological routes which generate 5 bio-based products for industrial applications, with attractive market opportunities: insect protein, disinfectant, microbial protein, ectoine and caproic acid. All value chains are based on new bioprocesses and/or innovative biofermentors combined with sustainable downstream processes, which will be validated at demo-scale at an industrial brewery. A min. 45% carbon footprint reduction will be achieved in each value chain. The evaluation of CHEERS impacts will consider go beyond the classic LCA and will cover broader impacts such as biodiversity and land use. The beer company MAHOU is project coordinator and exploitation leader jointly with 11 partners of 5 European countries, including technology suppliers, end-users and research entities. CHEERS will contribute to a “zero waste” biorefinery approach, fully aligned with the EU Green Deal, Circular Economy Action Plan and Bioeconomy Strateg
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'NeuroCOGNitive impact of Air pollution exposures in Childhood: Assessment of air pollution effects on the development of cognition and behaviour in children'.

assistant: **Concept**

Neurological disorders such as Autism Spectral Disorders (ASD) in children  are lifelong conditions for which there is no cure,treatment options are very limited AND create huge burdens on children, families and society. Potential long-term consequences of poor cognitive performance and presence of autistic traits are poor social development, low educational achievement, diminished economic productivity and unemployment, mental health issues, and increased risk of antisocial behaviour. In the case of ASD, a lifelong disorder, there is no cure and limited treatment options are available. Therefore, it is essential to identify modifiable risk factors to prevent their onset and prevalence. Air pollution is postulated as a risk factor since it is believed to cause neuroinflammation, oxidative stress and neurodegenerative pathology. Traffic noise shows inconclusive associations with cognitive performance. The experience in cognitive and neurobehavioral development epidemiologic analysis and wide-scale modelling at the host institution, with different modelling approaches and existing models available for UK and London at the partner´s institutions, and the experience of exposure assessment methods of the fellow dovetail nicely to accomplish the goal of the COGNAC project. This is to explore the associations between air pollution and noise with cognitive performance and the presence of autistic traits in children using a large children cohort. The innovative aspects of this proposal are combining multi-pollutant and noise exposure, using very detailed maps of these environmental stressors and assessing effects at critical windows of exposure. The scientific impact of this fellowship results from the identification of the effect of air pollution and noise in cognitive developm
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Deciphering cell heterogeneity in tumors using arrays of nanowires to controllably poke single cells in longitudinal studies' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Cancer is responsible for 20% of all deaths in Europe. Current cancer research is based on cell ensemble measurements or on snapshot studies of individual cells. However, cancer is a systemic disease, involving many cells that interact and evolve over time in a complex manner, which cell ensemble studies and snapshot studies cannot grasp. It is therefore crucial to investigate cancer at the single cell level and in longitudinal studies (over time). Despite the recent developments in micro- and nanotechnologies, combined with live cell imaging, today, there is no method available that meets the crucial need for global monitoring of individual cell responses to stimuli/perturbation in real-time.  This project addresses this crucial need by combining super resolution live-cell imaging and the development of sensors, as well as injection devices based on vertical nanowire arrays. The devices will penetrate multiple single cells in a fully controlled manner, with minimal invasiveness.The objectives of the project are:1) To develop nanowire based-tools in order to gain controlled and reliable access to the cell interior with minimal invasiveness.2) Developing mRNA sensing and biomolecule injection capabilities based on nanowires.3) Performing longitudinal single cell studies in tumours, including monitoring gene expression in real time, under controlled cell perturbation.By enabling global, long term monitoring of individual tumour cells submitted to controlled stimuli, the project will open up new horizons in Biology and in Medical Research. It will enable ground-breaking discoveries in understanding the complexity of molecular events underlying the disease. This cross-disciplinary project will lead to paradigm-shifting research, which will enable the development of optimal
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'automated in-line separatioN and dEtection of eXtracellular vesicles for liqUid biopsy applicationS' (NEXUS) targeting Horizon Europe.

assistant: **Abstract**

The NEXUS project will develop an easily customizable integrated platform to enable Extracellular Vesicles (EVs) separation, purification and multivariate characterization from complex biofluids. EVs enclose a heterogeneous group of cell-released membranous vesicles, abundantly present in body fluids from which they can be extracted in a non-invasive manner. Their surface markers and cargo (proteins, nucleic acids, glycans, lipids) represent an ideal source of diagnostic, prognostic and efficacy biomarkers, providing real-time information on tissue homeostasis alterations. However, their detection and molecular profiling is technically challenging due to their physical characteristics and huge heterogeneity. The previous FET project INDEX has validated at lab scale (TRL4) an integration of a selective sequential isolation and in situ enrichment of small EVs (sEVs) from plasma, with the multiparameter analysis regarding vesicle size, number and immunophenotype. NEXUS aims at proceeding towards industrialisation by delivering a manufacturable, full-fledged analytical instrument, characterised by an appealing ?sample in ? result out? design and featuring a real time in liquid measurement of scalable sample volumes. NEXUS breakthrough technology will be achieved through integration of: i) innovative chemistry for reversible sEVs immunocapture with unique Capture-Release-Re-capture features; ii) microfluidic extraction and pre-concentration of cancer sEVs; iii) DNA barcoded customizable chips for single sEV capture and analysis. Fully automated Interferometric Reflectance Imaging Sensor providing rapid, sensitive and multiplex profiling of cancer proteins, displayed on sEVs without the interference of soluble proteins and confounding particles (other sEVs and lipoproteins),
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'EQualIS : Enhancing the Quality of Interacting Systems' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

The ubiquitous use of computerized systems, and their increasingcomplexity, demand formal evidences of their correctness. Whilecurrent formal-verification techniques have already been applied to anumber of case studies, they are not sufficient yet to fully analyzeseveral aspects of complex systems such as communication networks,embedded systems or industrial controllers.  There are three importantcharacteristics of these systems which need to be tackled:- the rich interaction that crucially constrains the behaviour ofsuch systems is poorly taken into account in the actual models;- the imprecisions and uncertainty inherent to systems that areimplemented (e.g. on a digital processor), or which interact via anetwork, or which control physical equipments, are mostly ignoredby the verification process;- the deployment of large interacting systems emphasizes the lack fora modular approach to the synthesis of systems.The goal of this project is to develop a systematic approach to theformal analysis of interacting systems.  We will use models from gametheory for properly taking into account the interaction in thosesystems, and will propose quantitative measures of correctness andquality, that will take into account the possible perturbations in thesystems. The core of the project will be the development of variousalgorithms for synthesizing high-quality interactive systems. We willbe particularly attached to the modularity of the approach and to thedevelopment of efficient algorithms. The EQualIS project will deeplyimpact the design and verification of interacting systems, byproviding a rich framework, that will increase our confidence in theanalysis of such systems.