RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Additive Manufacturing Aiming Towards Zero Waste & Efficient Production of High-Tech Metal Products' (AMAZE) targeting Seventh Framework.

assistant: **Abstract**

The overarching goal of AMAZE is to rapidly produce large defect-free additively-manufactured (AM) metallic components up to 2 metres in size, ideally with close to zero waste, for use in the following high-tech sectors namely: aeronautics, space, automotive, nuclear fusion and tooling.Four pilot-scale industrial AM factories will be established and enhanced, thereby giving EU manufacturers and end-users a world-dominant position with respect to AM production of high-value metallic parts, by 2016. A further aim is to achieve 50% cost reduction for finished parts, compared to traditional processing.The project will design, demonstrate and deliver a modular streamlined work-flow at factory level, offering maximum processing flexibility during AM, a major reduction in non-added-value delays, as well as a 50% reduction in shop-floor space compared with conventional factories.AMAZE will dramatically increase the commercial use of adaptronics, in-situ sensing, process feedback, novel post-processing and clean-rooms in AM, so that (i) overall quality levels are improved, (ii) dimensional accuracy is increased by 25% (iii) build rates are increased by a factor of 10, and (iv) industrial scrap rates are slashed to <5%.Scientifically, the critical links between alloy composition, powder/wire production, additive processing, microstructural evolution, defect formation and the final properties of metallic AM parts will be examined and understood. This knowledge will be used to validate multi-level process models that can predict AM processes, part quality and performance.In order to turn additive manufacturing into a mainstream industrial process, a sharp focus will also be drawn on pre-normative work, standardisation and certification, in collaboration with ISO, ASTM and ECSS.The
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Development of New therapies against cholangiopathies.' under Horizon 2020.

assistant: **Concept**

Cholangiopathies represent a diverse group of diseases affecting cholangiocytes which are the main cell type of the biliary tract. These disorders range from inherited (Cystic Fibrosis) and developmental (Alagille Syndrome, Biliary Atresia) to autoimmune (Primary Biliary Cirrhosis), idiopathic (Primary Sclerosing Cholangitis) and drug or toxin induced diseases. Cholangiopathies result in toxic bile accumulation in the liver inducing cell death and ultimately cirrhosis. They carry high morbidity and mortality, accounting for up to a third of chronic liver disorders. Whole liver transplantation remains the main treatment. However, organ transplant requires immunosuppression with significant side effects and an increasing number of patients die while on the transplant list due to the shortage of suitable donors. Finally, the absence of physiologically relevant in vitro systems to model and to study cholangiopathies prevents the development of new therapeutics while cell based therapy approach have been unexplored. Here, we propose to systematically address these challenges by developing a novel and innovative program of translational research focusing on cholangiopathies. We will first investigate the cellular and functional diversity of the biliary tract and its impact on disease by taking advantage of recent developments in single cell transcriptomic analyses. We will then use this basic knowledge to generate and to characterize for the first time a renewable source of cholangiocytes from human induced pluripotent stem cells and from biliary tissue. The resulting cells will be used to model cholangiopathies in vitro and to create a new platform for drug target identification. Finally, we will explore the potential for in vitro generated cholangiocytes to be used in regen
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Thermodynamics of trace element partitioning between minerals and melts' (1994-1998), addressing dissemination and exploitation.

assistant: **Impact**

Research objectives and content The project addresses the fundamental problem of how trace components partition between solid and melt or fluid phases. The principle objective is to develop a rigorous predictive model for trace element partitioning between silicate minerals and melt using as a starting point the preliminary thermodynamic model of Blundy & Wood (Nature, 1994). This will be extended and refined via two complementary approaches. First, high temperature-high pressure experiments will be performed in doped natural and analogue chemical systems to determine the partitioning behaviour of selected trace elements between mantle minerals (garnet, pyroxenes, olivine)and coexisting melts. Experimental conditions will be varied so as to isolate the effects of pressure,temperature and phase composition. Experiments will be performed in piston cylinder and multi-anvil apparata; trace elements will be analysed by ion- microprobe. Second,these data will be used as input for thermodynamic modelling of partitioning. Training content (objective, benefit and expected impact) Research will involve training in silicate synthesis methods and high pressure experimental techniques, together with several analytical techniques,including electron microprobe analysis,ion- microprobe analysis,X-ray diffraction,ICP-MS and FTIR. The research will be carried out in the UK's foremost experimental geochemistry laboratory, offering considerable opportunity to interact with other researchers in this field.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'High-quality Energy Performance Assessment and Certification in Europe Accelerating Deep Energy Renovation (QualDeEPC)' (QualDeEPC), addressing dissemination and exploitation.

assistant: **Impact**

The QualDeEPC project is aiming to both improve quality and cross-EU convergence of Ener-gy Performance Certificate (EPC) schemes, and the link between EPCs and deep renovation: High-quality Energy Performance Assessment and Certification in Europe Accelerating Deep Energy Renovation (QualDeEPC). The objective of the project is to improve the practical implementation of the assessment, is-suance, design, and use of EPCs as well as their renovation recommendations, in the partici-pating countries and beyond. Recommendations for renovation shall be made coherent with deep energy renovation towards a nearly-zero energy building stock by 2050. In order to reach these objectives, the project will organise its activities in four stages: 1 | Analysis of existing EPC schemes, good practice, shortcomings, and priorities for improvement 2 | Development and testing of concrete proposals and tools for enhanced EPC assessment, certifi-cation, and verification, as well as Deep Renovation Network Platforms 3 | Adaptation to country needs and implementation of consensus elements, and developing a roadmap for further dialogue and  4 | Sustainability Strategy and Conclusive policy recommendations, dialogue, and transfer. Project partners will work to achieve consensus and implementation during the project for as many improvements as possible, seeking the cooperation of certification bodies, energy agen-cies and other organisations. Some of these are project partners, many others agreed to sup-port the project as associated partners. However, many of the potential improvements to EPC assessment, certification, and independent monitoring and verification will need adaptation of standards, regulations, or even legislation. The QualDeEPC project will stimulate such changes by (1) intensive d
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Optical probing of charge traps in organic field-effect transistors' (OPTOCHARGE).

assistant: **Concept**

Organic electronics offers huge potential for fabrication of large-area, low-cost, and efficient devices. Solution processing and availability of a vast library of organic semiconductors enables to exquisitely tailor properties to each application, while minimising waste of materials and maintaining low temperatures during processing thus reducing energy use. Although organic electronic devices have reached the market in large and flexible displays, their real potential in biomedical applications, sensing, and sustainable electronics remains unrealised. Crucial fundamental building blocks, such as organic field-effect transistors, are still hindered by limited charge mobility and unpredictable outcomes with new material recipes. Organic semiconductor performance is significantly reduced by formation of charge traps, which are local defects in the material or interfaces that remove charge carriers from the device conduction channels and obstruct transport. Accurate control of charge traps is critical to boost device performance, but they are notoriously difficult to identify, characterise and rationally engineer. OPTOCHARGE adopts a novel approach to optically stimulate traps with high spatial, temporal, and energy resolution, and reveal the key parameters for charge trap optimisation. The project systematically explores crystallinity, morphology, material blends, dopants and electrolyte gating to dissect the origin of traps and offer effective strategies to boost device performance. The proposal leverages unique interdisciplinary synergies between applicant and host, and provides an outstanding research setting to fulfil the full potential of the applicant and launch his academic career.


**Keywords:** Organic semiconductors, Organic electronics, Organic field-effect t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Network for promotion of RT results in the field of Eco-building technologies, small polygeneration and renewable heating and cooling technologies for buildings' will create measurable scientific, societal and economic impact aligned with Sixth Framework.

assistant: **Impact**

PEP-Net will give support to the bundling and sharing of European Research know how in three thematic areas: eco-buildings, small polygeneration and renewable energy heating and cooling technologies. Promotion needs information, which needs to be easily accessible, easily understood and easily useable to fulfil its obligation to become wide-spread knowledge and develop a visible impact.Targeting researchers and technology experts, manufacturers that could produce, enterprises that can apply new technologies, planners and architects, and associations of enterprises and other relevant actors, the proposed actions will increase the level of information and know-how among the relevant market actors regarding new RTD results of the three thematic areas, help spur market implementation and thus stimulate and facilitate transfer of knowledge regarding RTD results and applications throughout Europe.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'How does autophagy rescue stalled ribosomes?', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Multiple ribosomes simultaneously move along the mRNAs to translate the genes into proteins. Cellular stress triggers collisions of ribosomes and disrupts protein synthesis. Eukaryotes have evolved multi-tiered quality control mechanisms that monitor ribosomes and rescue them on collision. While much is known about the rescue of cytosolic ribosomes, how the cell rescues stalled endoplasmic reticulum bound (ER-bound) ribosomes remains unknown. We recently discovered that the stalling of ER-bound ribosomes induces autophagy, a major cellular degradation pathway. We discovered two autophagy receptors that are induced upon stalling of ER-bound ribosomes and these proteins are conserved between plants and humans. We also showed that ufmylation, an elusive posttranslational modification system regulates ER-bound ribosome stalling-induced autophagy. These two discoveries indicate that autophagy plays a major role in the maintenance of a functional ER-bound ribosome population. Based on these discoveries, I hypothesize that autophagy rescues stalled ER-bound ribosomes by selectively degrading harmful polypeptides and RNAs that clog the ribosomes during collisions. Here, I propose to define and characterize this conserved quality control mechanism. I will establish a suite of complementary methods in the model plants Arabidopsis thaliana and Marchantia polymorpha to explore the physiological significance of autophagy-mediated ribosomal rescue (RiboRescuePhagy) in complex multicellular organisms. In parallel, I will carry out unbiased genetic screens in human cell lines to discover the molecular components that mediate RiboRescuePhagy. Finally, I will perform structure-function analysis of a key ufmylation enzyme to untangle the connection between ufmylation and autophagy. At the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Contradicting responses to multiple stressors reduce the resilience of zooplankton community' (CONTRASTRESS) under Seventh Framework.

assistant: **Objectives**

The aim of the project is to find out what happens within zooplankton communitiy when various chemicals (cyanotoxins and infochemicals) force organisms to use contradictory strategies. Aquatic ecosystems are subject to many anthropogenic stressors, which includes eutrophication with toxic cyanobacterial blooms, chemical pollution (e.g. pesticides) and invasive species linked with climate change. These factors modify populations and whole lake ecosystem as well. Also natural factors like predation, resource competition and food quality may cause substantial changes in populations and communities. Organisms need to use different strategies to cope with these stressors and these strategies exclude each other. This situation may lead to losses in genetic biodiversity or even to exclusion of a species. Zooplankton plays important role in aquatic food webs and it is crucial to know how chemical interactions affect population dynamics and community structure. The aim of this study is to check what are the strategies of individuals to cope with such contrasting conditions and what is their role in biodiversity loss. To answer these questions several approaches will be used to bring together paleolimnology, evolutionary ecology and ecotoxicology. Molecular biology will be included as well in order to asses the genetic biodiversity and to develop a new tool for testing the response of an organism to chemical stressors. Two main hypotheses will be tested (1) Hormesis of a trait is maladaptive (i.e. strategy ‘bigger is better’ decreases fitness and hence indicates a negative response), (2) Interaction of cyanotoxins (hormesis) with fish infochemicals can induce developement of a new zooplankton community. Based on these working hypotheses we set several objectives: - to describe th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Agricultural member state modelling for the EU and Eastern European countries' demonstrating excellence, impact and implementation quality for a Sixth Framework call.

assistant: **Abstract**

The 36 months project will aim to develop medium term projections for a set of relevant agricultural sectors in the EU and in a wider European context. It will measure the effects of alternative domestic agricultural and trade policies on EU agricultural markets and sectoral income. To fulfil these aims, dynamic partial multi-country multi-market equilibrium models will be developed that capture policy instruments and model European prices endogenously. As the assessment of the impact of agricultural policies at the country level crucially depends on the level of EU prices, the major aim of the proposal is to develop an EU composite model comprised of national country models. In addition to national country level models for EU-25 Member States, country models will also be constructed for EU Candidate Countries and other European countries. For each country modelled and for the combined EU-25, the AGMEMOD 2020 model will generate the main domestic market variables for each agricultural commodity, including: annual quantities produced, consumption (feed and non-feed), imports, exports and changes in stock, areas of crops and numbers of animals, agricultural commodity prices, and agricultural sector income. Furthermore, the models will cover European markets for the grains, rice, oilseeds, root crops, livestock and meat, eggs milk and milk products, wine, cotton, tobacco, olive oil, fruit and vegetables. Projections will be provided over a medium term time horizon. On the project's completion it will be possible to make projections to the year 2020. Further enhancement of the information content of the models will be achieved through consultation with multidisciplinary Advisory Groups, including commodity market experts. Dissemination will be enhanced by a dedicated commun
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fifth Framework proposal on 'Polymer molecular modeling at integrated length/time scales'.

assistant: **Innovation**

The PMILS proposal addresses the fundamental question of predicting macroscopic properties for polymeric materials from their molecular constitution and processing history. In order to tackle this long-standing problem we will combine a wide range of expertise in modeling tools (quantum mechanical, molecular, mesoscopic, macroscopic) and experimental methods. Essential innovations of the project are: i) organization of these methods in a systematic hierarchical approach ii) use of integration tools. We will develop an understanding of the mechanisms responsible for polymer performance using techniques not available through the most advanced commercial software. We will apply that understanding to a selected set of industrially relevant problems. The main expected result is an integrated design tool for polymer materials able to predict properties from molecular structure and processing history
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Digital twins for the optimization of agrifood value chain processes and the supply of quality biomass for bio-processing' under Horizon 2020.

assistant: **Concept**

The EU agri-food sector is at a crossroads. The sector endures a string of crisis, suffering from losses and inefficiencies that affect the overall system efficiency, whilst the society expects always more to be done on environmental protection, and on providing secure, nutritional, and healthy food, demanding high added value products of sustainable production and verifiable traceability. To tackle these challenges, BBTWINS will develop and validate two innovative digital twins in two use cases in Spain and Greece (meat and fruit production) following a multi-actor approach and integrating into a single platform all the processing steps (from crop to final products) and the valorisation of the bio-streams generated using innovative processing treatments. The use cases will be addressed following a holistic approach including an environmental, social, and economic assessment, and logistic issues. The digital twins developed will integrate enabling technologies such as artificial intelligence, Internet of Things, and software analytics, together with blockchain and strategic and operational logistic solutions in a single platform. BBTWINS digital twins will: (i) increase biomass availability, resource efficiency and sustainability for the bio-based industry, (ii) lower biomass losses from feedstock supply through the processing stages of the value chain; and (iii) allow a longer storage time before processing through more efficient pre-treatment steps and storage methods to better preserve the valuable components.BBTWINS will validate at least 3 new products for the bio-based industry such as bioactive compounds for nutritional foods and nutraceutical products, fertilizers, protein concentrates for feed, and snacks.The BBTWINS multi-actor consortium is constituted by 3 R