RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'How do galaxies get their gas?' under Seventh Framework.

assistant: **Concept**

Observing the evolution of galaxies over cosmic time is one of the key priorities for the new Square Kilometre Array (SKA), the next-generation radio telescope that will be built in South Africa and Australia over the next decade. Its large size and extreme sensitivity mean it will have a huge impact on astrophysics. In the run-up to the SKA, several SKA-precursor telescopes are starting to probe SKA science already. We describe a project covering an important aspect of one of the SKA science questions, namely to establish where the gas in galaxies comes from. Galaxies seem to form stars at a rate that makes it impossible to sustain their current gas reservoirs over the lifetime of the universe. They must therefore continuously acquire pristine gas from somewhere. Theory predicts the existence of a ""cosmic web"" of gas and dark matter surrounding the galaxies which provides this new fuel.  With ultra-sensitive observations it will be possible to directly observe this ""accretion"" of gas. Using the Dutch APERTIF, the Australian ASKAP and the South African MeerKAT SKA precursor telescopes (this project has already been allocated 8 months of observing time on the latter), we will directly observe the presence and establish the importance of accretion. The outcome will have a significant impact on our current models for galaxy evolution, and will guide future SKA work. This project also fulfills the recent call of the European Parliament for greater collaboration with Africa in the field of radio astronomy (Written Declaration 45/2011).""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Adventure with nuclear spin-isomers: separation, physical chemistry and applications of ortho- and para-water' will create measurable scientific, societal and economic impact aligned with Sixth Framework.

assistant: **Impact**

The two identical H atoms in the water molecule exist in two forms, with total nuclear spin number 1 (ortho isomer, o-) or zero (para isomer, p-) respectively. The equilibrium o/p ratio at RT is 3:1, but it has been recently shown that mixtures enriched i n one isomeric species can be obtained by selective adsorption onto aluminum oxide or activated coal surfaces. The quantitation of the o/p ratio has been possible by means of submillimeter IR spectroscopy.The consequences of this breakthrough are not yet fully appreciated. Indeed, due to the central role of water for life on Earth, the availability of water with altered o/p ratio can be of paramount importance and may open new, highly innovative applications in a number of fields, ranging from medicine, biology, chemistry to earth sciences, meteorology etc. This Adventure project aims at exploring the feasibility of some of these exciting applications.To this end, it will deal with:1) Optimising the separation methods of o-and p-water isomers;2) Developing new methods of identification and quantitation of o- and p-water; in particular, NMR approaches will be developed (17O,1H);3) Understanding (and controlling) the determinants responsible for o- and p-isomers' lifetimes;4) Characterizing the physico-chemical properties of the two isomers and studying natural and artificial systems displaying non-equilibrium o/p ratios. The different properties of the o- and p- isomers may open new adventures in the study of the spatial distribution in water containing objects, ranging from inorganic objects to biological systems, and the o/p ratio could be used as a sensor to assess functionality changes in material science and in living systems.5) Designing new and innovative contrast agents for MRI, based on the peculiar properties
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Risk Stratification for Sudden Cardiac Death' (RISTRAD).

assistant: **Concept**

Sudden cardiac death (SCD) is a leading cause of total and cardiovascular mortality. Ventricular fibrillation (VF) is the most common arrhythmia causing SCD. In young individuals, SCD occurs primarily in the setting of rare cardiac disorders generally considered as Mendelian diseases. Among these are the primary electrical disorders associating lethal arrhythmias such as VF. These disorders are highly amenable to genetic studies since they manifest clinically with specific features on the electrocardiogram.As of today, the large gap in our knowledge concerning the determinants of VF at the genetic and molecular level hinders breakthroughs in the development of risk stratification and preventive strategies. As a model of a primary rhythm disorder, Brugada syndrome (BrS may be considered as 'sensitized model' for SCD and be relevant to the broad problem of SCD in the setting of common cardiac pathologies.The aim of this project is to prpose a translational study, combining genome wide association studies in the largest biobank of patients with cardiac arrhythmia ever collected, genotype-phenotype studies for clinical relevance/use and functional characterization for novel genes uncovered.The overarching aim of the study is to decipher the genetic model of the BrS by identifying novel genetic factors that modulate risk for SCD. We also believe that the impact of this project, although focused on a rare disease such as Brs, will be much broader in the field of cardiac arrhythmias and more generally for SCD.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fifth Framework proposal on 'Training on production and use of laboratory reference materials for use in routine quality control'.

assistant: **Innovation**

In support of quality control in routine laboratories in EU-Southern Member States and Associated States in the sector of environmental/agro/food analysis, practical training courses are proposed, with the final goal: - to help LRM production units to develop and become self-sustained (at the national and regional level); in a theoretical and practical training; participants will also prepare a LRM, the quality of which will be intercompared; the Workshop will be open to 12 additional participants from EU/Associated States; - to support dissemination of a common (multi-national) view on the use of laboratory reference materials in routine quality control (control charts) and in proficiency testing, training on these aspects is proposed ('training of trainers'), - to support national training initiatives on LRM use, organized in the respective national languages. A 'Manual on RM production' and 'Guidelines on LRM Use' will be prepared and disseminated; the latter will be translated into the languages of 4 southern EU and 2 Associated States to allow wide dissemination
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'A new bio-sensor concept for medical diagnosis: targeted micro-bubbles and remote ultrasound transduction' (TAMIRUT) targeting Sixth Framework.

assistant: **Abstract**

The overall objective of TAMIRUT is to develop an innovative bio-sensor concept devoted to advanced medical diagnosis, in which the biological material is carried by targeted micro-bubbles injected inside the body and the transducer is remote. The remote transducer operates on the basis of the ultrasound response of such micro-bubbles, gathered and processed by an improved version of an ultrasound medical scanner (UMS). Targeted micro-bubbles (similar to the generic micro-bubbles composing the contrast agents actually used in medical echography) are designed to bind only to a desired target region: a bio-conjugate ligand is attached to micro-bubble shells producing the adhesion of them to specific molecular signatures.The project goal is to exploit targeted micro-bubbles as bio-sensors producing measurements that will significantly complement the ultrasound molecular imaging and improve the medical diagnosis potential. Among many potential medical applications, the case study that will be addressed in the TAMIRUT project concerns the early detection, the assessment of the micro-vessel density, and the correct staging and grading of the prostate cancer. Such tasks will be dramatically improved by developing appropriate targeted micro-bubbles (i.e. bubbles able to bind on the endothelium of the neo-vessels of such a cancer) and measuring their local concentrations by means of the novel bio-sensor.In addition, the repetition over time of such a measurement could help in assessing the disease evolution, especially regarding the angiogenesis aspects. The main objective of this project will be pursued by a multidisciplinary, strictly joint development of all the bio-sensor components, taking into account the need to remotely interrogate targeted micro-bubbles. In turn, micro-
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Active Monitoring of Cancer As An Alternative To Surgery' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

When a patient is discovered to have cancer, one of the primary goals is to have the tumour removed by surgery. Althoughthis provides excellent oncological control, it is associated with morbidity and functional problems in cancer survivors. Recentstudies have shown that the immediacy to perform a resection does not always lead to improved clinical outcome.Furthermore, cancer surgery can often lead to complications where the quality of life for the patient is compromised by toxicside effects and /or damage to nerves, organs or healthy tissues. A number of recent clinical trials in the field of cancersurgery have advocated the concept of watch and wait, watchful waiting, active monitoring or surveillance, which are termsused to describe a monitoring strategy for cancer. The concept may be antithetical but the functional advantage of thesealternatives is clear even though there is some concern about the risk. Though the evidence is still weak, current studiessuggest that with adequate selection and follow-up, this oncological risk is small. A major consideration for clinicians is nowto maintain quality of life for all patients. Our objective in this proposal is to implement novel approaches so that cancersurgery can be avoided, where we aim to (a) develop new monitoring technologies from industry so that the surveillancewindow can be increased to allow for better treatment options over time and to avoid surgery, (b) develop new ‘watch andwait’ strategies in order to study the behaviour of the cancer so that any risks to the patient can be minimised leading to abetter clinical outcome and (c) train a new generation of preclinical and clinical scientists to be able to implement this newconcept as standard of care and to maximise the benefits of an active monitoring policy.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'Production forecasting with uncertainty quantification'.

assistant: **Concept**

Objectives It is becoming increasingly important to quantify accurately the economic risk associated with hydrocarbon development projects. In particular, the marginal fields in the North Sea require optimal use of all available information to assess the associated economic risks. These data need to be combined in a formally unbiased way that honours the information content inherent in the data. Statistical theory provides the formal framework in which the 'Uncertainty' can be 'Managed'. PUNQ is aimed at further developing a methodology to quantify and reduce the uncertainty in production forecasts obtained from computer simulations of hydrocarbon reservoir models. Technical Approach Reservoir simulation models are generally conditioned directly to static information obtained from well logs, and indirectly to the reservoir's observed historical dynamic performance such as well pressures, water-gas ratios, etc. PUNQ follows a Bayesian framework in which the unknown reservoir parameters, expected to have a first order effect on predicted performance, have to be estimated using a priori information on these parameters, and using an inversion process routinely referred to as History Matching (HM). Geologists and reservoir engineers integrate their respective views at an early stage by jointly selecting the HM-parameters, and by defining a priori probability density functions (PDF) of these parameters. A likelihood function, or HM-response surface, is then constructed, describing the probability density that a given parameter combination can reproduce the observed production behaviour. The main technical objectives of the project are as follows: - development of techniques for mapping HM-response surfaces in the multi-parameter space; - development of techniques for projecti
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Dielectric measurement of two-dimentionally confined biomolecules at the nanoscale' (Dielec2DBiomolecules) targeting Horizon 2020.

assistant: **Abstract**

Macromolecular organization and interactions have long been recognized to be strongly influenced by electrostatic and electrodynamics interactions which in turn depend on the molecular polarizability. In particular, molecular polarization plays a fundamental role in the molecular structure of biomolecules like DNA and proteins. Yet, this physical property of biomolecules has remained almost unexplored so far because measurements on the molecular scale are a technical challenge. Previous experimental work mostly relied on standard approaches as such broadband dielectric spectroscopy which are limited to the micrometer scale and, therefore, cannot resolve the polarization properties of single molecules. Hence, new experimental approaches are needed to measure the polarizability of molecules at molecular level. In this project, we will tackle this important issue and develop a novel experimental platform that will allow to access for the first time the polarizability of biomolecules under two-dimensional (2D) confinement. This will be achieved by coupling two novel technologies of nanoscience: scanning dielectric microscopy, a recently developed scanning probe technique, and the 2D-materials technology. We will engineer novel 2D liquid cells by assembling 2D crystals, and we will measure the dielectric properties of the biomolecules confined inside using a scanning probe. This is an ambitious experimental research with a strong interdisciplinary and groundbreaking nature, based on the powerful combination of new microscopic approaches with novel 2D materials. The developed platform will access previously unknown physical properties of biomolecules that are crucial to understand their behaviour. It will provide much-needed feedback for first-principles and mean-field theori
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Centre of Excellence for Exascale in Solid Earth' (ChEESE), addressing dissemination and exploitation.

assistant: **Impact**

This proposal aims at establishing a Center of Excellence to prepare flagship codes and enable services for Exascale supercomputing in the area of Solid Earth (SE). ChEESE will harness European institutions in charge of operational monitoring networks, tier-0 supercomputing centers, academia, hardware developers and third-parties from SMEs, Industry and public-governance. The scientific ambition is to prepare 10 flagship codes to address Exascale Computing Challenging (ECC) problems on computational seismology, magnetohydrodynamics, physical volcanology, tsunamis, and data analysis and predictive techniques for earthquake and volcano monitoring. The codes will be audited and optimized at both intranode level (including heterogeneous computing nodes) and internode level on Exascale architecture hardware prototypes (co-design approach). Preparation to Exascale will also consider code inter-kernel aspects of simulation workflows. First, ChEESE will develop Pilot Demonstrators (PD) for scientific problems requiring of Exascale computing on near real-time seismic simulations and full-wave inversion, ensemble-based volcanic ash dispersal, faster than real-time tsunami simulations and physics-based hazard assessments for seismics, volcanoes and tsunamis. Second, pilots will serve to enable services on urgent computing, early warning forecast of geohazards, hazard assessment and data analytics. Selected pilots will be tested in an operational environment and made available to a broader user community. Additionally, and in collaboration with the European Plate Observing System (EPOS), ChEESE will promote and facilitate the integration of HPC services to widen the access to codes to the SE users community. Finally, ChEESE aims at acting as a hub to foster HPC across the Solid Ear
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Multiple stall levels', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

Objectives of the project The majority of wind turbines installed in Europe and of those produced at present, use aerodynamic stall as a method of power limitation in high wind speeds. A considerable number of these stall controlled wind turbines, with rotor blades produced by various manufacturers, installed at different locations, have shown a behaviour which is now commonly referred to as multiple stall behaviour. This phenomenon can be described as the occurrence of more then one stall power level under apparently equal conditions. Rotors displaying this behaviour can produce stall power at one level for longer periods of time (hours, or days) and then suddenly switch to a different (higher or lower) stall level at which they remain for some time. Up to four power levels have been identified for certain rotors; the difference between the highest and the lowest level can be 25 to 30% of nominal power. Usually, the high stall level coincides with the design level, or nominal generator power. This means that at the lower power levels, energy production will be below the guaranteed power curve level and rotor blade manufacturers are quite concerned. As stated above, the problem is not blade or industry specific, but of a generic nature. The basic objective of this project is to identify ways to prevent or control the multiple stall behaviour. To achieve this, the underlying cause(s) must be known. Hence the collateral objective is to determine these cause(s). It is presently believed that the basic phenomenon is premature stall, but it is not clear what triggering mechanisms can be responsible for this, nor which parts of the blade(s) suffer changes in the 'regular' flow pattern. A solution to the problem is of high industrial relevance as it enables turbine manufacture
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Algebraic Geometry', explaining its relevance to EU policy priorities under Sixth Framework.

assistant: **Impact**

Algebraic geometry is one of the most prestigious fields in mathematics. However in Hungary, the study of this subject has not been part of the country's strong mathematical tradition. Recently a research group in the area has been formed at the host by internationally recognized researchers of the younger generation who studied in the great mathematical centres of the world.The main reason for carrying out the Transfer of Knowledge project is to develop the progressing algebraic geometry school into a mature centre. This way it contributes to the cohesion of the European research area insofar the existing disequilibrium in directions of research in Central Europe and in the EU will be eliminated. The Renyi Institute provides a friendly and stimulating atmosphere for research, which encourages the participation of both genders.In addition various EC funded conferences and Workshops demonstrate the ability of the algebraic geometry group to organize mathematical life in a way that knowledge reaches the interested scientists. Extensive scientific exchanges with European centres have been greatly accelerated by the FP5 grant Centre of Excellence. The ToK project would provide the opportunity to continue the highly successful CoE project.In order to solve various recent problems in algebraic geometry, it is essential to combine ideas from different sub-fields. One of the strength of the algebraic geometry group at the host is that its members' backgrounds are rather different, therefore the group is an ideal centre for transferring and amalgamating knowledge of various related areas.In addition the group is working in close collaboration with experts from neighbouring fields such as theoretical physics, combinatorics, differential topology, symplectic geometry and complex a