RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Innovative products obtained from fruits of sea buckthorn' in the context of a Fifth Framework call.

assistant: **Objectives**

The Romanian co-proposer Proplanta S.A. recently developed a process for the generation of a new caroteinoid-lipoprotein complex from Sea buckthorn fruits. The product is composed of carotenoid pigment complexes with lipoproteins, and vitamins C, E and F . The carotenoid-lipoprotein-complex has been shown to be a very effective carrier for antioxidant activity , which will penetrate more easily (for example) into the skin than current caroteinoid products. No other natural carrier system for carotenoids is know on the market. It can be expected that there will be a rising demand for well defined Sea buckthorn extracts as the number of cases of skin damage (from sunburn) and other skin defects (caused by the increasing UV irradiation resulting from climate changes in recent years) is ever increasing. In these cases natural Sea buckthorn extracts can be beneficial. The proposed project aims at developing applications for these extracts in the field of cosmetics, e.g. cosmetic additives for creams and gels exerting skin regenerative effects and photo protection cosmetic additive for skin regeneration in case of acute and chronic diseases and photo protection.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Dynamics and Structure of Networks' (DYNASNET).

assistant: **Innovation**

Networks define our life, being essential to cell biology, communications, social and economic systems, and impacting virtually all areas of science and technology. The aim of this proposal is to engage leading experts in network science and graph theory to build a mathematically sound theory of dynamical networks, which will be transformative to our understanding of complex systems, with applications in multiple disciplines. Both fields have made major conceptual advances in the past decade: network science has offered a data-based basic topological description of complex networks, and has started to address the inherently dynamical nature of real networks, their reconstruction and control; in mathematics we have seen major advances in graph limit theory, the local-global dichotomy in observation, and promising steps in the theory of graphs with intermediate degrees, that capture real networks. While these concepts offer different formalisms to capture the same underlying reality, there has been no conversation between the two communities, limiting our understanding of real networks. The proposed research aims to build on these advances to construct a coherent theory of dynamical networks, and to exploit its applications and predictive power to various real systems. We plan to offer a sound mathematical foundation of network science, helping us better analyze, predict and control the behavior of real networks. It will benefit mathematics in leading to an enriched, robust graph limit theory, with exciting applications in multiple areas of mathematics. To enhance the wider impact of the proposed mathematical advances, we plan to conduct a permanent conversation with experts from different domains that encounter and explore real networks, from cell biology to brain scienc
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Integration and Harmonization of Logistics Operations' (TRACE) under Horizon Europe.

assistant: **Objectives**

Logistics industry is facing continuous and significant challenges during the recent years. The trend is the adoption of intelligent services for increasing the performance of the provided systems and synchromodal operations. Transfers and deliveries can benefit from the use of novel business models that adopt the aforementioned intelligent services when the optimization of the use of shared resources is the core target and become the basis for the provision of a climate friendly infrastructure. The goal of synchromodal operations and the integration of heterogeneous logistics services is the reduction of current transfers in order to reduce the carbon footprint while securing the uninterrupted deliveries and the resilience to any disruptive event. TRACE targets to the aforementioned integration activities offering a universal platform with functionalities related to planning, scheduling, optimization and events management as well as the use of blockchain technology to facilitate the real time conclusion of smart contracts and financial operations, thus, becoming one of the first attempts to provide an ‘intelligent cover’ upon the current logistics frameworks. TRACE envisions real demonstrators in different European countries with different goals that start from transportations with the use of shared resources, the disruptive events detection and re-scheduling of transfers while concluding with the use of unmanned vehicles to automate the last mile deliveries. TRACE also proposes new transfer corridors, safe areas where unmanned vehicles can collect items towards the final destination and new (virtual) hubs. TRACE will perform studies related to the barriers towards the new logistics era, the new business opportunities, the requirements for the legislation and regulator
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Prediction of protein flexibility and its role in protein-protein interactions and binding specificity' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Recent studies show that protein function is not only determined by the static folded three-dimensional structure, but also by the distribution of the populations of its conformational sub-states within different environments. A detailed investigation of interacting protein interfaces requires - beyond the knowledge of their structure - information about their flexibility and the range of accessible conformations of the native state and complexed states. Additionally, successful protein structure prediction has demonstrated the suitability of “building blocks” (prototype fragments) as embodiment of local biological and physicochemical features. It is expected that the overall dynamics of protein structures can similarly be assembled from fragment flexibilities embedded in a known protein fold. Therefore this proposal focuses on developing a fast fragment-based method to predict the dynamics of a native or designed protein structure, which will be used to determine or define function in interaction networks and binding specificity in protein-ligand complexes. Specifically, the dynamics of prototypical fragments from a representative protein set will be sampled by molecular simulations; a flexibility predictor will be designed, implemented using Hidden Markov Model (HMM) and trained on dynamic profiles of the prototypical fragments; by using the flexibility predictor protein-protein and protein-ligand interactions will be investigated. For protein-protein interactions the flexibility of all known high-resolution protein structures will be predicted and made publicly available. To study flexibility as determinant of ligand-binding specificity, comparisons between the conformational sub-space of protein-ligand complexes and the space of all accessible conformations of the u
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'CENTRE FOR GLOBAL AND REGIONAL ETHNOGRAPHIES AT AARHUS UNIVERSITY' (GLOREA) targeting Seventh Framework.

assistant: **Abstract**

Proposal to create a research centre for PhD and Postdoc researchers, focusing on ethnographic studies of migration and mobility in Europe, North America and the Asia Pacific. The Centre will be the core component of a specially created five year, then permanent, Research Professorship at Aarhus University. Projects at the Centre will be generated with external funding for two areas, crucial for exploring the human dimensions of globalisation and regionalisation, and which grow out of the recent research of the coordinating DIrector (Adrian Favell): on migration and mobility at the East-West, Balkan and Mediterranean borders of Europe, in comparative regional perspective with Latin American-US migration and the Asia Pacific; and on flows and mobility of highly skilled, creative professionals between hub cities in Europe and East Asia. PhD and Postdoc researchers, who will be recruited internationally, will receive comprehensive methods training in quantitative and qualitative techniques, as well as specialist training as ethnographers. The IRG will enable the return of an established European researcher who has spent 7 years as an Associate Professor of Sociology at UCLA.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'GMES for Africa: Regional Network for Information Exchange and Training in Emergencies' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

To enable and enhance the ability of African states to use satellite Earth Observation for the management of natural and man-made humanitarian emergencies. To develop a network of EU, African organisations and African users, in order to build economic, technical and commercial capacity within African states, along the priority lines being identified in consultation with the African Union under the ‘GMES and Africa’ initiative.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'A new hope for early gonarthrosis treatment using a biotechnological therapeutic drug to regenerate cartilage by intra-articular knee injection' (RHYP) under Horizon 2020.

assistant: **Objectives**

The aim of RHYP is to sustain the commercialization of a new promising therapeutic product (REG-O3) to restore the joint function for the treatment of early and moderate gonarthrosis (GA). GA is a degenerative knee joint disease that represents a huge social and economic burden worldwide. According to the World Health Organization, more than 5% of people over 40 and 50% of people over 75 years suffer specifically from GA in developed countries. It affects also a growing number of younger people as athletes and obese people, among others. There are currently no therapeutic molecules on the market for the treatment of early GA to slow down or stop disease progression and avoid surgery joint replacement. Available treatments for this disease stage are mainly symptomatic, such as the widely use injection of hyaluronic acid (HA) in articulation (viscosupplementation – Global market €1.5 Mrd in 2014). RHYP’s ambition is to tackle this current drawback by pushing forward its drug candidate REG-O3 into clinics to propose a disruptive and long-term treatment (curative and symptomatic action) using a painless local administration mode at a competitive price (€450 for total treatment is estimated).The selected lead REG-O3 activity proof of concept on chondrocytes proliferation activation to slow down cartilage degradation was previously established in vitro and in vivo. Following successful feasibility studies conducted thanks to the European commission (EC) through the Phase 1 of the SME Instrument, RHYP is now responding to the topic “SMEInst-03-2016-2017” in phase 2. RHYP is now aiming, during this 24 months’ project with a EC requested contribution of €2,1 M, to plug the gap from TRL 6 to TRL 9 by launching REG-O3 GMP batch manufacturing and syringes conditioning to conduct Fi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Scanning Tunneling Microscopy Studies at High Magnetic Fields: Visualizing Pnictide and Heavy Fermion Superconductivity' in the context of a Seventh Framework call.

assistant: **Objectives**

The purpose of this project is to provide basic knowledge about how the properties of superconductors vary at the local level under strong magnetic fields. New phases such as the FFLO state in Pauli limited superconductors or fully polarized vortex phase in ferromagnetic heavy fermions have been predicted. However, no direct observation of such phases using real space imaging has been reported yet.  The goals of the project are to investigate unconventional high magnetic field superconducting phases and to understand their relationship with the normal state electronic structure. In particular, we will directly image the spatial variations in the superconducting pair function and determine the electronic structure through Landau level spectroscopic measurements. The latter is a new local technique which we will first implement here. To achieve these objectives, dilution refrigerator Scanning Tunneling Microscopy (STM) studies will be performed down to the mK regime and under magnetic fields up to 17 T. Within the project, a compact STM device will be built to operate at the highest available magnetic fields and enable the possibility of future STM measurements in international high field facilities. The microscopic approach to high field superconductivity proposed here will bring about new challenges and opportunities through the combination of local studies and novel superconducting properties.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Next Generation Health Technology Assessment to support patient-centred, societally oriented, real-time decision-making on access and reimbursement for health technologies throughout Europe' (HTx) under Horizon 2020.

assistant: **Objectives**

HTx will create a framework for next generation Health Technology Assessment (HTA) that supports patient-centred, societally oriented, and real-time decision-making for integrated healthcare throughout Europe. HTx will focus on therapeutic areas with high unmet need for which HTA information has to be provided on complex and personalised combinations of health technologies. Based on a select number of relevant case studies, HTx will enhance methods for integrating evidence from RCTs and real-world data (RWD). HTx will also augment statistical and econometric methods for generating robust estimates of effectiveness and cost-effectiveness in order to support relevant HTA decision-making for these complex and personalised combinations of health technologies. HTx will also contribute to improving methods to support personalised treatment advice fitted for sharing with patients and their physicians. This includes the development of statistical and econometric approaches and artificial intelligence/machine learning methods for forecasting treatment effects in specific groups of patients. Simultaneously, in close collaboration with the European Network for HTA (EUnetHTA), HTx will improve synergies between regulatory agencies, HTA bodies and clinical guideline developers. This will include the translation of HTx methods into already existing European guidelines, most prominently those developed by EUnetHTA. HTx will also support initial efforts to discuss reimbursement and funding models that facilitate controlled access to and the pricing of these complex health technologies. Finally, we will evaluate the transferability of HTx results into all EU Member Countries especially in Central and Eastern European (CEE) Countries and promote the dissemination of HTx results to the di
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'ACME, fly with me, fly with ACME' (ACME) under Horizon 2020.

assistant: **Objectives**

The main objective of the project is the implementation of a patented Octaspring® technology in the aviation industry. The ACME project represents a natural step in the business development strategy of the applicant, after a highly successful launch of the Octaspring technology in the mattress industry, a revolutionary solution, which is globally sold in over 30 countries.  Octaspring® as a Key Enabling Technology, a fusion of spring coil and memory foam/foam technology, provides a basis for disruptive innovation in a range of products made of foam or containing foam in finished products across industries. Thus, as the first and only of its kind, its lightweight structure brings incredible benefits to the aviation industry. ACME project will therefore deliver the development of an aircraft seat foam cushion composition with innovative lightweight cover, including mattresses for cabin crew and support pillows, to round up the product portfolio. The main goal is to achieve weight reduction of the aircraft, increased comfort and invigorating travel experience for passengers. ACME addresses the needs of the market segment of foams & fittings within the aircraft seating market, providing benefits to our end-users, who are clearly and perpetually articulating interest in our solution: aircraft manufacturers, aircraft seat manufacturers, airline companies and passengers. The development of ACME is driven by the market trends and needs for lightweight aircraft seats, demands for premium air travel, rise in aircraft orders and need for fuel efficiency, which are the crucial factors driving the market growth. Taking all this into consideration, our ACME solution contributes to the reduction of: fuel consumption of the aircraft (which typically accounts for 40-55% of operating exp
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Agile, eXtensible, fast I/O Module for the cyber-physical era', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

We are entering the Cyber-Physical age, in which both objects and people will become nodes of the same digital network for exchanging information. Therefore, in our imaginary, the general expectation is that “things” or systems will become somewhat smart as people, allowing rapid and close interactions not only system-system, but also human-system, system-human. More scientifically, we expect that such Cyber-Physical Systems (CPSs) will at least react in real-time, have enough computational power for the assigned tasks, consume the least possible energy for such task (energy efficiency), scale up through modularity, allow for an easy programmability across performance scaling and exploit at best existing standards at minimal costs. The whole set of these expectations impose scientific and technological challenges that need to be properly addressed.The AXIOM project (Agile, eXtensible, fast I/O Module) aims at researching new software/hardware architectures for CPSs to meet the above expectations. The technical approach aims at solving fundamental problems to enable easy programmability of multi-core multi-board systems through the open-source OmpSs programming model, leveraging Distributed Shared Memory (DSM) inspired concepts across the modules. The OmpSs will allow accelerating functions through an FPGA (Agility). In particular, to the best of our knowledge, this is the first time that DSM will be effectively demonstrated on an embedded modular system (eXtensibility). Modular scalability will be possible thanks to a fast interconnect that will enrich the module. To this aim, an innovative modular ARM-based board with enhanced capabilities for interfacing with the physical world will be designed and demonstrated in key scenarios such as Smart Video-Surveillance and Sma