RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Metallacrowns-based innovative materials and supramolecular devices' (METALLACROWNS) under Seventh Framework.

assistant: **Objectives**

This IRSES proposal has the objective to design innovative functional magnetic or fluorescent materials and probes based on metallacrown complexes.The project involves six research groups (4 EU and 2 from Other Third Countries) with complementary expertise and the common aim to develop new metallacrown complexes with novel magnetic, photophysical and structural properties be used as tools in bio- or nanotechnological devices. The partners involved in this project have already collaborated in the past and served as co-authors in several joint papers.Here, the partners aim to set up a common platform to promote and strengthen their joint activities through the support of the secondments of their researchers. Through this network, they will take advantage of the expertise and techniques available at their institutions on the synthesis, characterization and organization on surfaces of metal complexes to obtain materials, devices and probes for bio-nanotechnological applications. Training aspects will be considered in the project activities: graduate students and early career scientists will significantly improve their skills and expertise through their secondments to other laboratories, while the hosting institutions will benefit from visits of senior scientists and collaborators. Regular workshops and seminars delivered at the hosting institutions by the seconded researchers will also increase the visibility of the project.This IRSES eventually aims to establish and support multilateral transfer of knowledge and expertise among the involved EU and Extra-EU research teams. On one hand this will stimulate the aggregation of scientists into an EU to worldwide network on the research on functional materials and molecular devices, increasing in turn the competitiveness of ERA a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project '‘Key account management’ for the SME Instrument beneficiaries and ‘Enhancing SME innovation management capacity’ as new proinnovative services for SMEs in the regions of Southern Poland' (KAM2SouthPL2).

assistant: **Concept**

The general objective of the project is to contribute to smart growth of Southern regions of Poland by increasing the efficiency and effectiveness of investments in innovation and by contributing to more efficient connection of links along the innovation chain and by this – to contribute to the smart EU growth. The specific objectives of the project are: efficient management of the relation between SME (beneficiary of the SME Instrument) and the coach in purpose to increase the number of projects financed within Horizon 2020 programme completed with a successful commercialization and development of regional SME innovation management capacity: by carrying out innovation management gap analysis, development of the tailored action plan for increasing the effectiveness and efficiency of their innovation management system and implementation of the targeted actions to address bottlenecks and weak points between the innovation capabilities and innovation goals. The objectives will be achieved by performing two kinds of 7-days service packs: Key Account Manager and Enhancing SME innovation management capacity, based on the common for the whole Enterprise Europe Network standard, compliant with European Innovation Management standards - CEN/TS 16555:1(2013). The project is relevant to the Work Programme in Horizon 2020 and helps to overcome lack of capacity in innovation management, recognised as an important barrier in creating economic impact on innovation activities in SMEs. The project is addressed to the specific challenge and scope of the topic, as set out in the Work Programme and offers mentoring and coaching services to beneficiaries who need this help. The project will make SMEs high quality innovation support services available where these are absent or unaffordable o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Optical Topologic Logic' in the context of a Horizon 2020 call.

assistant: **Objectives**

The goal of this proposal is the development of light-induced and controlled topology for energy-efficient logic operations. We address the fact that 10% of the global energy production is used to power electronic circuits which perform logic operations for the global internet and in consumer devices, and that the projected energy consumption will increase by 20% by 2030. OPTOlogic envisions a new class of dissipation-less quantum devices generatedthrough spatially and temporally structured ultrafast pulses of light to artificially induce and control topological protected states. With OPTOlogic, we will prepare future quantum devices based on intrinsic and light-induced topological building blocks which move and store information with minimal energy expense, whilst achieving dramatically increased computing power. We will create a computing architecture that exploits light-induced topology within which near-arbitrary patterns can be written, changed, and re-written on the fly. The required breakthrough will be achieved with a multi-disciplinary team of experts and SME which unites world-leading experimental, theoretical, and industrial expertise in condensed matter physics,ultrafast laser technology, non-linear optics, strong-field physics, attosecond metrology, quantum optics and gauge theory, quantum computing, machine learning and artificial intelligence. Overall, increasing the energy efficiency and speed of logical operations, OPTOlogic would have a significant economic, environmental, and social impact and address a market which was valued 426.0 million USD in 2017.


**Keywords:** Optics, Ultrafast Physics, Strong field physics, HHG, Light-Matter Interactions, Topological Phase Transition
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Development of an energy efficient rotary kiln for the production of expanded slate aggregates from slate waste' (1998-2002).

assistant: **Concept**

To prepare a step 2 submission to design and build a kiln to produce expand slate aggregates from slate waste based on the design for a prototype kiln prepared under the framework 4 craft programme (development of expanded slate for horticultural and aggregate use) contract n° BRST-CT97-5210. The batch and tunnel kilns used for that programme are not suitable for production purposes but have provided the technical knowledge necessary to design and energy efficient rotary kiln which combines the use of gas and micro-wave energy and incorporates the time and heat parameters which the research showed were required to expand slate waste. The aim of the project is to demonstrate that an aggregate, which is suitable for use in a wide range of building materials and meets EU building product specifications, can be produced economically. The production would include a concrete block which would have twice the strength, four times the insulation value and yet only half the weight of a traditional block. The project would demonstrate the world-wide suitability of the plant for exploitation in the slate industry and the great environmental and economic benefits that would accrue.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'SINGLE-GRAIN RE-ENGINEERED ND-FE-B PERMANENT MAGNETS' (GREENE).

assistant: **Concept**

GREENE addresses one of the Europe’s Grand Societal Challenges, aligned with the European Green Deal and the recently released Green Deal Industrial Plan for the Net-Zero Age, which alongside the Circular Economy Action Plan, sets the framework for the transformation of the EU’s industry. Rare-earth-element (REE) permanent magnets based on Nd–Fe–B are vital for use in electric vehicles and wind turbines, making then central to Europe’s green-energy future.  These magnets have outstanding properties, but they are not without their weaknesses. There is, of course, the well-known dependence on imports from China, on which Europe is presently totally dependent. However, here, in line with the scope of the Resilient valu chains 2023 call, GREENE will focous on a redesign of Nd-Fe-B magnets as an advanced material where the Nd in the grain boundary is replaced. At the same time, we will address the problem of translating the under-used intrinsic properties of the hard-magnetic Nd2Fe14B phase into better extrinsic properties of the magnet. And, since the process will apply equally well to fresh or recycled feedstocks, we will also be impacting on the problem of supply dependence.


**Keywords:** rare earth-based permanent magnets, Nd-Fe-B, redesign and engineering in-situ, grain boundaries, recycling
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Positional cloning of a susceptibility gene for type 1 diabetes and otherautoimmune diseases on chromosome 3q' (1994-1998) under Fourth Framework.

assistant: **Objectives**

Research objectives and content  The aim of the proposed project is to continue the cloning and physical mapping of the diabetes susceptibility gene (IDDM9) on chromosome 3q22. This region is of special interest because it has also been linked to rheumatoid arthritis, inflammatory bowel disease and multiple sclerosis. So it may be an important overall autoirnmuoity locus. The IDDM9 locus has been localised to a 2 or 3 cM region. A physical map of at least I Mb of the central region containing polymorphic microsatellite markers associated with type I diabetes will be constructed in order to find the region of strongest allelic association and also to define haplotypes which allow fine mapping of the disease gene. Furthermore, genes will be characterised from the most associated region to define a subset of gene associated polymorphisms that can be considered as candidate polymorphisms for the aetiological variant responsible for the association and linkage of the region. Polymorphic microsatellites characterised from the region and also gene associated polymorphisms will be analysed in more than 2,000 families available in the Todd laboratory, providing a high power of statistical analysis. Ultimately these results will lead directly to functional analyses of higly associated polymorphisms in or near genes to ascertain the mechanism of IDDM9 in type 1 diabetes. Training content (objective, benefit and expected impact)  The objective is to become competent in all techoiques and approaches in statistical and molecular genetics as applied to the positional cloning of a susceptibility gene in a common disease. Insight into the genes and their variants that controlsusceptibility and protection from autoimmune disease will provide key information on disease mechanisms and help
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Day-by-Day Short-Term Traffic Forecasts for Road Concessions (top app)'.

assistant: **Objectives**

Exacto created a new methodology to produce short-term traffic forecasts for road concessions, for each of the 365/366 days of following year (Day-by-Day). A prototype version of an informatics application was produced and was successfully tested in 2015/2016 on four road concessions. Exacto now aims to fine-tune this prototype and turn it into a high-quality informatics application (top app) to sell it to road concessionaires worldwide. The innovative achievement is the production of daily traffic (which boosts accuracy, as current methodology only produces monthly forecasts), and also using an app to do it. Potential users are road concessionaires, and three of them were already contacted, with a very positive response towards being future clients. They have also invested in support of our application to SME Instrument. The commercial potential is huge, as there are >5000 concessions around the globe (growing rapidly). The concept is to sell one top app for each concession, so that the concessionaire can produce its own traffic forecasts, with minimum technical support.If a 20% market share is achieved, revenue will be 10 M€/year (after year 5). Extending to public Transport and other areas, revenue can grow to several times.Main advantages of top-app are:- Clear monitoring of traffic (daily, instead of monthly)- Significant accuracy increase- Useful info for concessionaire (can reduce traffic congestion, help better dimensioning of daily services)- Inexpensive/efficient way of producing their own traffic forecasts (automatically updated).In Phase1 Exacto will carry out a feasibility study, including:• Validation of top-app features• Finetuning the prototype (to complete in Phase2)• Audit results (University of Lisbon)• Explore IP regime• Prove commercial viability (i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Ultasonic diagnostic system to develop a non-destructive control for ornamental stones - uds' (1998-2002).

assistant: **Concept**

The research aims at developing an investigation method for detecting structural anomalies and inner defects in marble and granite blocks slabs and tiles. The objective of the proposed activity is the realization of an electronic system able to produce images for defects characterization (size location and growth direction). The system enables ornamental stone quality to be automatically determined in non-destructive way thereby saves costs in transporting poor quality blocks and allows a better planning of industrial activities accordingly. An ultrasonic investigation method will be developed and set up. Different section images are produced for different array locations and a qualitative three-dimensional view can be reconstructed for the sample stone. An experimental DB of ultrasonic information will be correlated to chemical-physical and mechanical characteristics of marble granite and natural stone. UDS will be integrative for the quality classification of ornamental stones.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Inductive Queries for Mining Patterns and Models' demonstrating excellence, impact and implementation quality for a Sixth Framework call.

assistant: **Abstract**

Given the present distinct lack of a generally accepted framework for data mining, the quest for such a framework is a major research priority. The most promising approach to this task is taken by inductive databases (IDBs), which contain not only data, but also patterns. Patterns can be either local patterns, such as frequent itemsets, which are of descriptive nature, or global models, such as decision trees, which are of predictive nature. In an IDB, inductive queries can be used to generate (mine), manipulate, and apply patterns. The IDB framework is appealing as a theory for data mining, because it employs declarative queries instead of ad hoc procedural constructs. Declarative queries are often formulated using constraints and inductive querying is closely related to constraint-based data mining. The IDB framework is also appealing for data mining applications, as it supports the process of knowledge discovery in databases (KDD): the results of one (inductive) query can be used as input for another and nontrivial multistep KDD scenarios can be supported, rather than just single data mining operations. The state-of-the-art in IDBs is that there exist various effective approaches to constraint-based mining (inductive querying) of local patterns, such as frequent item sets and sequences, most of which work in isolation. The proposed project aims to significantly advance the state-of-the-art by developing the theory of and practical approaches to inductive querying (constraint-based mining) of global models, as well as approaches to answering complex inductive queries that involve both local patterns and global models. Based on these, showcase applications/IDBs in the area of bioinformatics will be developed, where users will be able to query data about drug activity,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'The transversal social impact of gold metallurgy in ancient societies: a diachronic approach from Prehistoric Iberia.' (GOLDENIMPACT), addressing dissemination and exploitation.

assistant: **Impact**

GOLDENIMPACT aims to understand the social impact of gold technology implementation in all sectors of society and surpass outdated traditional narratives that solely understand gold as a consolidator of elite power. Hence, the project targets the study of gold production by 1) characterising existent technological traditions, 2) understanding the social consequences of metal cross-craft interactions affecting gold production, and 3) evaluating the extent and degree of novelty of the structural changes necessary to sustain gold production. Iberia was selected as case study (3100-1500 BC) for being an archaeologically rich area with an autochthonous development of metallurgy, and outside of the traditional research loci of ancient gold technology in Eurasia.To accomplish these objectives, this project uses a radically interdisciplinary methodology that combines knowledge from archaeology, anthropology and geology, with computational tools (R, QGIS) and materials science techniques (optical microscopy, pXRF, ICP-MS) to analyse selected gold items and deposits. As a result, it will be possible to reverse engineering and socially contextualise ancient gold production strategies and explore the links between technological and social change from a previously overlooked perspective (i.e. gold production). This will contribute to re-signify gold as a symbol of the achievements of non-elite people, and ultimately generate a more balanced narrative within the European history of technology, taking into account all society sectors and Europe’s Eastern periphery.


**Keywords:** Iberia, Chalcolithic, Early Bronze Age, gold technology, gold provenance, social complexity, identities, cross-craft interactions, technological traditions, optical microscopy, ICP-MS, pXRF
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Mitochondrial DNA degradation and sterile inflammation in the heart' (RAMBO).

assistant: **Innovation**

Heart failure is the leading cause of morbidity and mortality in developed countries including EU. Novel and efficient therapeutics to treat patient with heart failure have to be developed. Mitochondria are subcellular organelles that produce energy and dynamic organelles that fuse and divide. Dysregulated mitochondrial activity results in generation of free radicals which cause damage to cellular components. We reported that mitochondrial quality control by autophagy is essential for normal cardiac functions (Nat Med 2007). Mitochondrial DNA (mtDNA) contains bacteria-like unmethylated CpG motifs, which are inflammatogenic. We reported that mtDNA that escapes from autophagy-mediated degradation leads to inflammatory responses in cardiomyocytes and heart failure (Nature 2012). Damaged mitochondria in failing hearts are selectively removed by mitochondria-selective autophagy, mitophagy. Mitophagy is preceded by mitochondrial fission, which divides elongated mitochondria into pieces for autophagy. Although Atg32 is essential for mitophagy in yeast, no homologue has been known in mammals. Recently, we identified Bcl2-like protein 13 (Bcl2-L-13) as a functional mammalian homologue of Atg32 which induces mitochondrial fragmentation and mitophagy (Nat Commun in press) in mammalian cells. While methylation of nuclear DNA involves in epigenetic regulation of protein synthesis, the significance of mtDNA methylation in transcription and autophagy-medicated inflammation remains to be elucidated. Our pilot study showed an isoform of DNA methyltransferase targets to mitochondria for mtDNA methylation. In this proposal, we shall attempt to characterize regulation mechanism of Bcl2-L-13 and its in vivo function and to elucidate the physiological significance of mtDNA methylation. Furth