RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Australia-Spain Network for Innovation and Research Excellence', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

The Australia-Spain Network for Innovation and Research Excellence (AuSpire) is an ambitious interdisciplinary, intersectoral and international researcher training program that links Spanish and Australian research communities through 28 Postdoctoral Fellowships. Led by RMIT Europe, the AuSpire consortium consists of 15 contributing Partners (1 Beneficiary, 10 Implementing, 4 Associated) across academic and non-academic sectors in both countries (ES / AU). All Postdoctoral Fellows (PF) will be employed in Spain  by renowned companies, research centres and universities and benefit from international and intersectoral co-supervision and secondments with counterpart organisations in Spain and Australia.PFs will lead their own ground-breaking and innovative projects following their chosen research lines, and guided under the supervision of the top-class researchers and technical professionals at the Partner organisations. PFs will receive sector- and discipline-specific training to become specialists and experts in their chosen field or area, whilst also receiving training in transversal skills to broaden their knowledge and open up alternative career paths. Training workshops and meetings will be organised for and by the PFs as a common platform to provide the interdisciplinary and transversal training, as well as opportunities for strategic and structured networking across sectors – growing the PFs’ professional network opening career opportunities. Digital training will complement and expand on the in-person training workshops.A common theme of Planetary Wellbeing will underpin the workshops and overall training program, to ensure outputs from the research, innovation and co-creation activities offer true value to society and a positive impact on our planet’s inhabitants
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Probing and predicting the dynamical response of the Greenland-Ice-Sheet to surface melt water'.

assistant: **Innovation**

Over just three decades, the Greenland Ice Sheet contribution to sea-level rise has grown six-fold. Increased basal slipperiness from increased surface melt was initially proposed as a key mechanism reinforcing ice loss, but a wealth of studies deconstructed this idea, leading the Intergovernmental Panel on Climate Change (IPCC) to conclude that increased surface melt “has not led to sustained increases in glacier flux”. Last year, however, my group re-established meltwater as a primary mechanism driving ice dynamics, albeit in a different manner than previously envisioned. Basal slipperiness is not set by melt rates but by ice-sheet morphology, which drives low slipperiness in steep and fast glaciers that terminate into the ocean, and high slipperiness in gentle and slow glaciers that terminate on land. As a result, a previously unforeseen meltwater-ice dynamics feedback potentially drives a higher than anticipated mass loss as glaciers transition from marine- to land-terminating in the future.In this project, I plan to REASSESS the control of surface meltwater on ice loss from the changed paradigm that glacier morphology rather than melt rates controls its impact. (AIM1) will probe the mechanisms responsible for the morphology control on basal slipperiness by overcoming long-lasting observational challenges through an innovative seismologically- and geodetically-based monitoring scheme exporting recently established proofs of concept for the first time to Greenland.(AIM2) will predict the control of meltwater on ice-sheet evolution from incorporating the new observational insights from AIM1 into a hierarchy of small-scale physical to large-scale parametrized models.With this strategy, we will, for the first time, fully evaluate the dynamical response of the Greenland
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'New Technologies and Production Tools for Complex Protein Biologics' (COMPLEXINC), addressing dissemination and exploitation.

assistant: **Impact**

ComplexINC conceptualizes and systematically generates advanced tool-kits to enable high-throughput assembly of complex biologics and metabolic pathways in eukaryotic expression systems, for micro- to large scale production of high-quality protein specimens for drug discovery and as bio-therapeutics. Essential parts of these tool-kits will be innovative next-generation HT DNA assembly pipelines for automated multigene expression construct generation, a superior synthetic viral genome, genetically engineered animal and yeast cell lines with unique capabilities with respect to protein maturation and modification, as well as advanced methods for bioprocessing and integrated quality control. Putting these tools and production technologies in place will have a dramatic impact on the availability of challenging proteins and protein complexes including such of human origin, with tailor-made properties specifically geared towards their application in drug discovery and in the treatment of human diseases. The superior next generation technology platforms created within ComplexINC, the generated IP, protein targets and therapeutics will be commercially exploited, and serve as a nucleus to initiate a new start-up enterprise to commercialize high-end biologics discovery and production.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'A two-photon survey of the plasticity of the neocortical microcircuit: searching for plasticity hotspots' in the context of a Seventh Framework call.

assistant: **Objectives**

The cortex has been described to display synaptic plasticity, which is determinant for the function of cortical microcircuits. Although there is a large literature on neocortical plasticity, most of the experiments addressed the connections of pyramidal cells located in particular cortical layers, so the majority of intracortical connections are yet unexplored with respect to their plasticity. Moreover, these studies are contradictory in that apparently synaptic plasticity rules like spike-timing dependent plasticity (STDP) could be different in different neurons. Therefore, to understand the cortical microcircuit it appears necessary to characterize the different types of plasticity that these circuits are implementing and examine precisely how work the cell-specificity of the synaptic plasticity. The aim of this project is to characterize the plastic rules present among different subtypes of cortical neurons involved in a same microcircuit. I will focus on cortical microcircuit of pyramidal layer 5 cells which are the output cells of the cortex. Using calcium imaging coupled with two-photon photostimulation, I will identify connected cells and determine the extent of a cortical microcircuit that controls layer 5 cells. When connected cells will be identified, electrophysiological recordings and morphological reconstruction will allow me to characterize the cells involved in this microcircuit. I will characterize the plasticity forms which can occur between different connected cells using STDP protocols. The induced plasticity will be correlated with the nature and morphology of the considered connected cells to characterize the cellspecificity of the plasticity in a cortical microcircuit and to describe for the first time the rules of plasticity of cortical microcircu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'The times of their lives: towards precise narratives of change in the European Neolithic through formal chronological modelling' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

This proposal offers ground-breaking progress towards the construction of much more precise chronologies for the Neolithic period in Europe, through the complementary expertise of the P-I and Co-I in Neolithic archaeology and Bayesian statistical analysis respectively. The proposed project would provide much more precise timings of key features and trends in the European Neolithic sequence than are currently available, and much more precise estimates of the duration of events and phenomena, principally through the application of formal chronological modelling in a Bayesian statistical framework. From these it would open up fundamental new insights into the tempo of change through the detailed study of selected sites and situations across the span of the European Neolithic, especially in the sixth, fifth and fourth millennia cal BC. At stake is our ability to study the lives of Neolithic people everywhere at the scale of generations and even decades, as opposed to the more usual scale of centuries. The proposed project would develop the types of application of Bayesian chronological modelling currently undertaken and would offer the beginnings of a new kind of European prehistory, and the opportunity to rethink wider archaeological approaches to the study of time.The legacy of the project would be a series of case studies published in papers in leading journals, two books, and a series of seminars and conference presentations and sessions designed to reinforce best practice for the future.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'SOFTWARE PACKAGE IMPLEMENTING NOVEL OPTIMIZATION STRATEGIES APPLIED TO HIGH TECH PRODUCTS' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

Every aspect of the product life, from manufacturing to integration, can be investigated thanks to purpose-built simulators. By using a simulator, or a sequence of simulators it is quite easy to investigate a given design, but what happens if you want to investigate hundreds of alternatives and use the simulator as a decision tool to identify the best concept? The project SPINOSA intended to transfer simulation technology from electronic to acoustic and mechanical design. The output of this project was directed at solutions for noise and vibration reductions which, in addition to commercial benefits also have social and environmental impacts. Spinosa was concerned with the development and adaptation of software methods and products to provide computer models and simulations of prototypes - the particular application is for prototype domestic appliances (e.g. dishwashers) with reduced noise levels.The project was based on the capability of IMEC, a leading research institute in the field of electronic component design. IMEC had created a computer tool named NORMAN/DEBORA to assist the engineer in the design task. Basically, NORMAN defines a population of concepts (thicker, thinner, longer, shorter, in Aluminium or Steel, using this or that technology) and automatically runs all required simulators before gathering the important results and displaying in a meaningful way. DEBORA, NORMAN's sister program, is then used to identify the best mix of parameters leading to the optimal concept.NIT(also part of the LMS group) is the world leader in acoustic and vibration simulation tools and is a prime supplier of simulation tools for the transportation and appliances market. NIT has worked with IMEC to develop a product to help prototype a car or washing machine design that optimi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Energy Activated Citizens and Data-Driven Energy-Secure Communities for a Consumer-Centric Energy System' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

ENPOWER will design, develop and demonstrate SSH-driven methodologies, interactive and closed-loop tools, and data-driven services for energy-activated citizens and energy-secure cross-sector communities towards a citizen-centric energy system. We combine leading-edge ICTs with social/behavioural dimensions and with sharing economy and value stacking business models to deploy: 1) a Social Science Framework for energy citizens activation and innovative multi-dimensional incentives for citizens’ participation in energy markets; 2) AI-based consumers clustering and segmentation algorithms; 3) interactive tools and facilitation services for energy community planning; 4) Energy Data Space adaptation to support community-level data-driven activation and interoperable automated privacy and sovereignty-preserving Demand Response (DR); 5) P2P DLT/Blockchain digital marketplace for tokenized energy and non-energy assets reciprocal compensation; 6) data-driven services and apps for energy efficiency and activation performance management; 7) ICT services and Digital Twins for community-level energy optimization and aggregated flexibility management to trade off local self-consumption against grid service provisioning, while boosting a beyond-energy community social welfare; 8) Edge monitoring hubs for automated DR; 9) Business Sandbox for novel sharing economy and social innovation-based business models; 10) methodologies for evaluating different energy community setups, upscaling and replication. ENPOWER framework will be validated along 4 Front Runners energy communities pilots and further replicated in 2 Early Adopters, covering different levels of maturity of communities, to demonstrate increased RES local self-consumption and consumers participation to the energy markets, whil
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'BlueBio4Future – Blue Biotechnology and Bioengineering for the Current and Future Development of a Blue Bioeconomy in Portugal' (BlueBio4Future), addressing dissemination and exploitation.

assistant: **Impact**

Marine Biotechnology (MB) was identified by the EU Blue Growth Strategy (2012) as an enabling activity of high potential for the bioeconomy of Europe. Many products from marine biotechnology are already used in global markets for food and feed, cosmetics, aquaculture, agriculture, chemistry and pharmacology. Nevertheless, the potential for new products development is huge since marine biodiversity and in special, the marine microbiome, is far from being known and exploited. For that purpose, the aspects of Bioengineering - bioprocesses, synthetic biology, green chemistry and bioinformatics - are fundamental. BlueBio4Future aims to enhance CIIMAR research excellence in MB area, in special Bioengineering, contributing to increase attractiveness for outstanding researchers and to establish a long-term impact at regional, national and European levels. The ERA Chair holder will establish a high-performing team in MB at CIIMAR, contributing to increase the knowledge and competitiveness of CIIMAR in the area of MB. This will be done by attracting funds at national and international level, by the supervision of MSc and PhD students, producing high-ranked research outputs, protecting intellectual property and transferring knowledge to stakeholders and contributing to increase literacy in MB. In order to produce structural changes at CIIMAR in the area of MB, there is a need to attract outstanding researchers in the field of Bioengineering that could implement the framework for strengthening a long-term research and innovation enabling environment in the area of MB. The establishment of the ERA CHAIR BlueBio4Future will increase the levels of the research activity in the area of bioengineering in CIIMAR, enhance the capability of the CIIMAR to succeed in competitive research fund
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Laser induced nanojet functionalization of two-dimensional materials for sensing and energy harvesting applications'.

assistant: **Objectives**

The project will make an impact in important societal needs in the fields of energy harvesting and sensing for environmental, safety, and medical applications, which are relevant to the entire global population. The development of any of these high-tech areas is associated with the use of new materials. The scope of this proposal is to advance 2D materials by adding to them novel functionalities for improved energy-harvesting and sensing applications. Such 2D materials as graphene and transition metal dichalcogenides were selected for functionalization. The creation of nanopores or the attachment of chemically active compounds will significantly expand the capabilities of such materials, for example, it will enable the development of universal chemical sensors for the detection of volatile organic compounds. The project proposes to solve an important problem of functionalization, localized on nanoscale, which will allow minimizing the proposed devices.The disruptive technique to be used in this proposal for nanometer-precision patterning of 2D materials is based on one of the latest nanophotonics advancements, the photonic nanojets. It is possible to functionalize 2D materials by laser with spatial resolutions significantly lower than the diffraction limit, as light in a photonic nanojet can be concentrated into a volume that is one order of magnitude smaller. The project provides for a fairly simple and scalable technology. The low technological hazard of the method and invariance for materials are the basis for economic feasibility. New materials and devices arising from this project will be exploited by the industry, strengthening the EU economy and technological excellence in the fields of energy, electronic technology, health industry, security, environmental and i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Identification of novel regulators of translesion DNA synthesis in human cells'.

assistant: **Innovation**

Here, I propose to unravel the molecular mechanisms that regulate TLS during DNA damage bypass through advanced complementary approaches.Thousands of DNA damaging insults are inflicted daily upon the genomes of all living cells. If left unrepaired, these lesions can be life-threatening for organisms as they alter the content and organization of the genetic material. To overcome this constant challenge, cells are equipped with a global DNA damage response that impacts on diverse cellular processes to facilitate reestablishment of genome integrity. The genome is particularly vulnerable to DNA damage during DNA replication, where DNA is precisely duplicated as part of the cell division process. Translesion DNA synthesis (TLS), mediated by specialized low-fidelity DNA polymerases, is an important cellular mechanism for preventing gross chromosomal instability following DNA damage encountered during DNA replication. However, our understanding of how this is achieved at the molecular level remains surprisingly limited.First, in combination with state-of-the-art mass spectrometry facilities present at the CPR, I will set up a newly established screening method, termed BioID, for efficient, unbiased identification of novel proteins that specifically act at replication forks during TLS. Second, I will mine proteomic screens for DNA damage-regulated ubiquitylation for novel TLS-regulating factors. From these screens I will select the most promising candidate proteins for further validation and characterization of their potential roles in TLS regulation. I will study how these proteins impact on TLS by establishing cell lines capable of overexpressing or knocking down each factor, and employ these in a panel of biochemical and cell-based methods established in the host lab.This pr