RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'In vivo molecular imaging with adjustable oligonucleotide ligands' goes beyond current state-of-the-art under Fifth Framework.

assistant: **Innovation**

Our aim is to link non-invasive imaging and nucleic acid biotechnology to create new in vivo imaging methods. Oligonucleotide ligands termed aptamers bind with high affinity biological targets and can be obtained from large combinatorial libraries. Modified aptamers engineered to resist degradation and target molecular markers of disease are thus promising candidates both as diagnostic tools and as therapeutic agents. Using non-invasive imaging procedures (PET) , we will evaluate in animal models of disease the potential of stable aptamers for diagnostic and therapy. This project merges 6 groups specialized in the following fields:i) biologically-stable aptamer production (including a leading biotech company);ii) study of biomarkers in animal disease models, andiii) in vivo imaging methods. The major spin-off expected is the creation of generic methods for diagnosis and evaluation of new therapies.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'International competition and the internal organisation of firms'.

assistant: **Objectives**

It has been claimed that one important source of the economic gains from the Common Market is the increased internal efficiency of firms due to higher competition on the integrated market. Even though intuitive, theoretical work in the 90s has failed to give clear support for this view. The direct link between the internal structure of the firm and trade has not been addressed. My project aims to fill some of this gap. It will apply recent advances in the areas of contract theory and the economics of information as well as evolutionary game theory to international trade models. Using a detailed institutional theory of the firm allows to study the impact of different trade policies like import tariff reduction, export subsidies and non-participation in trade liberalisation by trading partners on internal efficiency. Empirical work at a later stage intends to test the implications of the theoretical models.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'A Novel Double Wheel Rake Machine to provide high quality fodder and high operational speed', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Dirty fodder is directly responsible of many serious problems in EU agriculture sector: the 2.5 % of cattle dye by Clostridia and the milk production chain is reduced of almost 5% due to the presence of dust and stones (technically ash content) into the fodder. In addition, dirty triggers fermentation processes which destroy the fodder itself. In 2016 just in Hungary 1,000 tonnes of fodder have been lost for this reason. Farmers are demanding high quality forage which can ensure maximising diary production. Current windrowing machines share serious limitations in terms of productivity and quality of forage: to date it does not exists a universal solution able to provide good quality forage at a reasonable working speed and with a low initial investment. At the time of making good fodder quality, raking is a key element because during this process the fodder is always in contact with the ground and it could be lifted and mixed with dust and stones. Our company has more than 100 year of history in the agricultural market with a high specialisation in hay making sector. We gained a strong reputation through the fodder cleanliness (which distinguishes our company policy) and the high quality that always has characterized our products. With RA-RAKE we will provide a windrowing machine that will be far better than the best-selling windrower (rotary rakes): it will be able to provide cleaner forage (1.8% ash content vs 7.5%) at a higher speed (≥20 km/h vs 12 km/h) and with a lower initial investment (reduced 35%). This will have a disruptive impact at many levels: a) for our company, permitting a 750% increase of our revenue and + 31 new employees; b) for the end user, as RA-RAKE will permit to save more than 43,000 € per year and c) for EU as it will permit to save more than
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Predicting and managing plant population responses in human altered ecosystems' (POP-CHANGE), addressing dissemination and exploitation.

assistant: **Impact**

Humans are rapidly changing the environments that plant and animal populations exist in. In order to make predictions about which populations will persist, which we are likely to lose and where to best place our management efforts for biodiversity conservation and ecosystem services we need a fundamental understanding of how the environment affects population growth and decline in human altered ecosystems. The proposed research seeks to leverage existing data-sets on plant population dynamics and spatial locations to gain insight into how abiotic conditions affect the growth, survival and reproduction of 162 species of plants worldwide. New data will be collected to extensively sample the population dynamics of a widespread plant species to develop novel models of habitat suitability for population growth at the global scale. Statistical models will be developed from existing data on 86 plant species at >40 sites worldwide to determine whether plant population responses to nutrient addition can be predicted using known demographic attributes, these models will be tested using new data from approx. 30 sites worldwide. Ultimately we need to use our knowledge of ecology together with the efficacy and costs of management to determine cost effective interventions to achieve environmental or societal goals. I will use demographic data on >20 plant species together with new management data to develop comparative models of cost effective management strategies for problematic invasive plants. I will use these interlinked objectives to develop predictive models of plant population dynamics under altered environmental conditions, predictions of population response to nutrient addition and general guidelines on how best to manage damaging pest species. The CIG will enable this rese
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'The transcriptional network of the zinc-finger factor ZEB1 and its function in the embryonic nervous system and glioma development' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

Current interest in neural stem cells derives from the prospect of using them in brain repair strategies, but also to understand neurodevelopmental pathologies.  This will require, however, a significant improvement of our understanding of the gene expression programs associated with their maintenance and differentiation, and how these are regulated.  Recently, several lines of evidence suggest a regulatory function for the zinc-finger transcription factor ZEB1, both in embryonic neural stem/progenitor cells, and in human tumours of neural origin.  Here we propose to use a multidisciplinary approach, combining mouse genetics and genomics, to characterize the function of ZEB1 in neural development.  A thorough phenotypic analysis of ZEB1 loss-of-function mouse models will be performed, with a special focus on its role in neural progenitors.  This will be complemented with the genome-wide characterization of its transcriptional network, using a combination of genomic location analysis with expression profiling.  Moreover, a detailed comparison of the ZEB1 transcriptional programs in human foetal- and glioma-derived stem cells will be carried out, providing important insights into ZEB1 function in tumour initiation and development.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'tRNA homeostasis and gene regulation' (2007-2013), addressing dissemination and exploitation.

assistant: **Impact**

Regulation of gene expression is a fundamental process in all cellular systems. While the major steps in gene regulation such as transcription and translation are well understood, the role of tRNA availability (e.g. abundance, half-life) in regulating translation is largely unknown. The ultimate objective of this proposal is to investigate how tRNA availability within a cell can influence which mRNA molecules are actively translated by the ribosome. More specifically, it aims to address (i) whether mechanisms such as transcription, nucleo-cytoplasmic transport and degradation vary for individual tRNAs coding for different amino acids and (ii) how altered tRNA dynamics can affect protein abundance, and hence fitness, in different cellular conditions.To address these questions, I propose systematically charting the tRNA abundance landscape using yeast as a model organism.  I will quantitatively investigate the processes of tRNA production, transport and degradation, in order to determine which steps in tRNA homeostasis are altered under diverse stress conditions, compared to optimal growth conditions. I will then investigate the impact of tRNA dynamics in cell fitness through competitive growth experiments. In this manner, I propose to construct the first dynamic map of tRNA abundance, which holds the potential to help understand the process of gene expression regulation in fine detail.In the long-term, the goals described in this proposal will not only provide new insights into regulatory mechanisms of protein translation but will also help to achieve a better understanding of factors that influence fitness and cell survival. With recent discoveries relating changes in tRNA abundance to apoptosis and gene misregulation in tumorigenic cells, future research on understandi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'An evolutionary approach to automated norm synthesis for multi agent systems' (EVNSMAS) targeting Horizon 2020.

assistant: **Abstract**

The field of multi-agent systems (MAS) is concerned with the theory, design, and implementation of systems of semi-autonomous software agents that operate in an environment, and typically have conflicting goals. A key issue in such domains is that of coordination: how to design agents to minimise any potential negative aspects of their interactions, and to maximise any potential positive aspects. A key approach to coordination is that of normative systems. A normative system defines constraints on the behaviour of agents to coordinate their interactions. This research programme is at the intersection of normative systems design and evolutionary game theory (EGT). EGT studies how evolutionary forces can lead populations to game theoretic solutions, and has been useful in understanding, for example the distributions of populations of species in habitats. The hypotheses of this project are that (1) EGT can provide a useful mathematical framework to model and understand normative systems in MAS; and (2) EGT techniques can provide a powerful framework to engineer normative systems for MAS. Thus, norm synthesis will consist of an evolutionary process in which most successful norms will prosper, while unsuccessful norms will be naturally discarded. The tools used to understand such norms will be solution concepts from EGT - notably the concept of an evolutionarily stable strategy. In this project we will develop both frameworks for understanding EGT for normative systems design and to synthesise normative systems for MAS, and we will empirically investigate our techniques in the context of two application domains. To carry out this project the fellow will be trained in classical game theory and EGT. To this aim he will benefit from supervision of Prof Michael Wooldridge, and c
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Migration Waves and their Contributions to Economic and Political Institutions in Origin Countries'.

assistant: **Innovation**

The ongoing global migration crisis has emerged as an important development challenge of our time, with millions of individuals crossing borders in search of better economic prospects, political liberties, & social stability. This research project examines how African European immigrants can contribute positively to their home countries' stability and institutional quality. The study highlights a transition from ""brain drain"" to ""institutional gain,"" where the potential benefits a country can derive from the skills & knowledge acquired by individuals who have migrated and gained experience & expertise abroad outweigh the loss of talent & skills shortages due to emigration. This research aims to rigorously explore and critically evaluate the potential impact African immigrants in Europe may have on the economic & political institutions development of their countries of origin. It aims to delve into the intricate dynamics that shape this relationship, focusing on the diaspora’s engagements’ quantitative & qualitative contributions. We seek to provide a comprehensive analysis of the myriad ways these migrants might be contributing to or detracting from the development of their home countries, considering factors including, but not limited to, remittances, knowledge transfer, investment, and influence on governance & institutional quality. We will conduct our research using quantitative & qualitative data collection techniques and diverse methods of empirical analysis. One subproject involves a cross-country study covering several African and European nations. Additionally, we will conduct case studies and comparative analyses focusing on diaspora communities from selected African countries that have demonstrated noticeable influences on their home countries' political
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Arena-Master Mobile Solution for Complete Synthetic Turf Recycling On-site' under Horizon 2020.

assistant: **Concept**

Over 600 000 tonnes of rubber crumb, silica and polymers mixed wastes are generated from used artificial grass fields each year in Europe. Based on the current market trends the total market volume and waste generation will increase more than 5-times by 2022, causing a huge environmental impact.Despite the growing popularity and implementation of artificial grass fields, there are no unified regulations or procedures for its EOL management. Current recycling technologies enable only low-efficiency infill separation from the artificial grass that is also time consuming, expensive and unsustainable. Therefore, most field owners landfill the used turf without any recycling, creating a big environmental impact and increasing the need for raw materials in new installations.ASIE, company with over 20-years of experience in installing artificial grass fields, has developed the first mobile and complete artificial grass recycling line that helps to lower the synthetic turf EOL management costs by up to 40-50% and increase the artificial grass sustainable management recycling rates. Compared to alternative solutions, we ensure:• 2x better infill separation (100%)• 4x faster old turf removal (1 day)• 2x faster field renewal (7 days)• 30-40% cheaper field renewalOur goal is to achieve a zero-waste concept and improve the ecologic and economic sustainability of artificial grass installations. Our unique mobile technology enables to reuse about 95% of the used materials in new artificial grass application or as a raw material in other industries together with:• 100% infill materials and polyethylene reclaim• 4x better turf removal enabling re-installation• 6x reduced transportation needs, leading to 95% less CO2 emissionsOur total addressable market in Europe is €350 million annuall
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Optimisation of typing policies for european marrow donors registries: socio-economic evaluation of molecular techniques and recruitment strategies' goes beyond current state-of-the-art under Fifth Framework.

assistant: **Innovation**

Although 6 million potential donors are registered worldwide, finding a donor compatible for allogeneic stern cell graft is hard because of HLA polymorphism. MADO (Marrow Donors) aims at evaluating optimisation of Registries in Europe by increasing the proportion of donors with rare HLA types to reduce inequality of patients in a cost/effective way. The main concept is an evolving filter to screen potential donors at low cost before full HLA typing for the likely presence of frequent types, using new markers and techniques. Organisational scenarios will then be designed. MADO involves 9 WP over 2 years and 12 partners in EU countries: 4 European Registries, sociologists, economists, public health unit, immunogenetics/molecular laboratories, bioinformatics, industry.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'INtelligent Security and PervasIve tRust for 5G and Beyond' in the context of a Horizon 2020 call.

assistant: **Objectives**

The goal of INSPIRE-5Gplus is to advance security of 5G and Beyond networks via two main approaches: (1) by leveraging/extending existing assets such as Trusted Execution Environments (TEEs), Remote Attestation/Path Proof/RCA (Root Cause Analysis), and end-to-end liability management between parties, and (2) by introducing novel solutions/paradigms exploiting the potential of new trends including AI/ML and Blockchains. Accordingly, the INSPIRE-5Gplus project will address key security challenges against the concrete and efficient realisation of 5G through vertical applications, ranging from autonomous and connected cars to Critical Industry 4.0 (under specific regulation constraints). Grounded in an integrated network management system and relevant frameworks, INSPIRE-5Gplus is entirely devoted to improve security at various dimensions (i.e., overall vision, use cases, architecture, integration to network management, assets, and models). It is also committed to deliver actionable results and enablers for all relevant stakeholders at both Program and Community levels. These outcomes will serve the crucial objectives of intelligent security and pervasive trust for future connected systems where Security will not be software-defined only, but will also be governed by Algorithms (AI, ML, Modeling, Optimization) to realize new concepts such as pro-active security while being trustworthy. Through its objectives, INSPIRE-5Gplus will deliver unique assets to achieve intelligent and trusted multi-tenancy (i.e. confident, evidence-based, and liable) across multi-tenants infrastructure, whilst also improving the control of systems, vulnerabilities and compromises for the infrastructure owners and tenants.


**Keywords:** Smart and Software-defined Security, Trust and Liability, 5G