RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Protein engineering for encapsulation and intracellular transport' (PROTENGENCTRANS), addressing dissemination and exploitation.

assistant: **Impact**

The main goal of this project is to develop a system for effective encapsulation and transport of negatively charged guests into living cells using an enginnered protein capsid. The research in prof. Hilvert's group demonstrated that it is possible to engineer the inner surface of a capsid formed by lumazine synthase from Aquifex aeolicus (AaLS) to accept positively charged guests while retaining the icosahedral structure. In my project I will be addressing the following issues: - Engineering the inner surface of the AaLS to express positively charged aminoacid residues maintaining the ability of the mutant to form an icosahedral capsid - Investigating stability and potential selectivity of guest encapsulation by the modified capsid - Attaching a delivery tag to the outer surface of the capsid in order to make it cell-permeable - Enabling efficient release of the cargo after cellular uptake, by attaching a degradation tag. The proposed project will provide us with a complete system for coating, intracellular transport and release of negatively charged biomolecules. It will be used to internalize membrane-impermeable molecules like siRNA, negatively charged GFP, and in perspective other proteins or oligonucleotide-based molecules. Based on our results, novel systems for regulating gene expression and investigating mechanisms of RNA interference may be developed. The use of a protein as the encapsulating agent will help to overcome shortages of existing systems for gene therapy using viral vectors, like mutagenesis or immune response. It raises hope for future medical applications of our results.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Sixth Framework proposal on 'Ultra portable augmented reality for industrial maintenance applications'.

assistant: **Concept**

Augmented Reality is an ideal technology for industrial service and maintenance applications. Computer-generated information are blended in the field of view of the technician, so that they appear overlaid to the real scene and demonstrate step by step complex reparation tasks. Nevertheless existing solutions require bulky hardware, severely limiting their usability.The objective of this project is to develop an ultra portable" system by applying augmented reality techniques to Pocket-PCs. This will offer a comfortable and unobtrusive solution, integrating augmented-reality functionalities with near-the-eye display, wireless connection, and remote support over integrated mobile phone. The development does not suffer from the development of specific and expensive wearable computers, but relies on the solid market of mobile handheld-devices.The challenge consists in developing a high-performance run-time system, including all the excepted augmented reality functionalities on a small device with very limited capacity, and in the same time, in providing all the necessary tools for the creation and management of the content. The result of the project will be an ultra-light and compact system with appropriate software for authoring, workflow editor/engine, context management, tele-consultation and augmented reality. It will enable an efficient production of electronic augmented reality manuals, thanks the authoring-system and the workflow editor, and the on-site support of the mobile workers.The required information will be presented in a small monocular eye-display as text, animation, and 3d-graphics correctly registered on images of the real scene, which will be taken by the user when required. The interactions will be achieved over pen on the PocketPC-display, for example
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Bringing AI Planning to the European AI On-Demand Platform' under Horizon 2020.

assistant: **Concept**

Automated Planning and Scheduling is a central research area in AI that has been studied since the inception of the field and where European research has been making strong contributions over decades. Planning is a decision-making technology that consists in reasoning on a predictive model of a system being controlled and deciding how and when to act in order to achieve a desired objective.  It is a relevant technology for many application areas that need quick, automated and optimal decisions, like agile manufacturing, agrifood or logistics. Although there is a wealth of techniques that are mature in terms of science and systems, several obstacles hinder their adoption, thus preventing them from making the footprint on European industry that they should make. For example, it is hard for practitioners to find the right techniques for a given planning problem, there are no shared standards to use them, and there is no easy access to expertise on how to encode domain knowledge into a planner. The AIPlan4EU project will bring AI planning as a first-class citizen in the European AI On-Demand (AI4EU) Platform by developing a uniform, user-centered framework to access the existing planning technology and by devising concrete guidelines for innovators and practitioners on how to use this technology. To do so, we will consider use-cases from diverse application areas that will drive the design and the development of the framework, and include  several available planning systems as engines that can be selected to solve practical problems. We  will develop a general and planner-agnostic API that will both be served by the AI4EU platform and be available as a resource to be integrated into  the users' systems. The framework will be validated on use-cases both from within the conso
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Human element in man/machine interface and interaction to improve safety and effectiveness transport for the European fleet', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

The main objective of MASIS II series of four packages can be stated as follows:To improve human behaviour on board ships with special attention to emergency situations, by providing practical tools and solutions which can be readily implemented in order to enhanceon-board and on-shore management and improve the working condition of shipboard personnel.This would involve devising appropriate tools and procedures for effective man/machine interface so as to reduce the impact of human element in marine incidents.These objectives will include also the proper ISM code manual as well as the new STCW impact evaluation and will be pursued through the development of several co-ordinate and linked work task, which comply with the terms of reference of the EU work programme.Further objectives are:a) Assess the remedial measures for enhanced efficiency and safety in emergency situations;b) Define the specific operational requirements for multi-cultural crewsc) Develop new employment/organisational models to enhance the attractiveness of working at sead) Introduce new concepts of management structures for shipowners and ship operatorse) Identify ship design requirements under ergonomic aspects for a reduction of operator workload and increase his comfort and alertness.f) Give imput to new educational and training programmes. %
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Spectrum Aggregation and Multi-User MIMO: Real-world Impact' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

Next generation cellular wireless systems will require data rates which are one order of magnitude higher than the ones provided by current systems.<br/>One way to improve the rates is to increase the bandwidth. Unfortunately, spectrum is a fragmented resource and large bands of frequencies are unavailable to one single operator. Therefore, Spectrum Aggregation (SA) represents an opportunity to overcome this limitation, putting together several non-contiguous frequency channels to benefit from a larger bandwidth in a single communication link. Conceptually simple, this idea brings significant technical challenges in developing system and user equipments.<br/>Data rates can also be increased by improving the spectral efficiency. It can be achieved using MIMO (Multiple-Input-Multiple-Output) systems. Single-User MIMO (SU-MIMO) systems have proved their potential and are already included in several standards, such as WiFi, WiMAX and 3GPP LTE. Multi-User MIMO (MU-MIMO) has been introduced in order to exploit the same benefits also at system level in multiple access systems. Although much research has been done, practical implementations are still unavailable.<br/>The goal of the SAMURAI project is to demonstrate the benefits of MU-MIMO and SA in real-world scenarios and at the system level. To achieve these targets, real-time testbeds will be set up for both schemes. In addition, the benefits of combining the two techniques will be investigated. Practical challenges like user scheduling, imperfect channel state information, and hardware/software implementation issues will be addressed.<br/>SAMURAI will push the state-of-the-art in wireless cellular communications. Proof-of-concepts and system simulations will provide recommendations for technical choices in standardization
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Iii-v antimony-based strained-layer quantum structures for mid-infrared injection lasers' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

The purpose of this project is to make headway in the field of mid-infrared semiconductor laser diodes (LD) and light-emitting diodes (LEDs) in the 2-3.5µm wavelength range.This challenging objective will be accomplished by a collaborative research effort of new Antimony-based heterostructures. These narrow-bandgap quantum-well structures are good candidates for roomtemperature (temperature-stabilised) mid-infrared laser operation in the 2-3.5µm range which this project aims to demonstrate by researching the radiative optical transitions and Auger losses in these uncharted heterostructures.The consortium is formed by three research laboratories working in the area of Antimony-based 2-5µm optoelectronic devices and one manufacturer, who will use combined expertise in III-V Antimonide semiconductor growth, materials analysis, laser processing and system design to target specifically the field of III-V antimonide infrared lasers as an important and useful class of sensing devices. To convincingly prove one of the major industrial applications, a sensing tool for specific trace gas detection (by means of tunable diode-laser absorption spectroscopy TDLAS) and for hazardous gas monitoring (HGM) will be demonstrated.A fundamental materials study consisting of epitaxial growth, physical analysis and theoretical modelling will be performed which is absolutely indispensable to improve the quality of these materials and interfaces. A theoretical study of Sb-based heterostructures including band structure and Auger recombination calculations will also be performed since it is the detrimental factor in narrow-bandgap emitters and a comprehensive theoretical understanding is lacking.The importance of strain, quantization and spatially-indirect transitions for strongly reducing Auger
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'External and Internal Human Exposure in Urban EXposome' in the context of a Horizon 2020 call.

assistant: **Objectives**

More than half of the world population lives in urbanized areas, and the size of the urban population is continuously increasing. Urban populations are exposed to a large number of environmental influences that can negatively affect human health. In response to the urgent need to understand the impact of the urban environment on human health the new concept of the “urban exposome” has emerged. The aim of this project is to develop a strategic partnership of the RECETOX Centre in the Czech Republic, one of the Widening countries, with two leading international counterparts at the EU level (UCL in the UK, ISGlobal in Spain and UU in the Netherlands) to establish scientific collaboration and networking activities among these institutions to increase European research excellence in the area of the urban exposome. RECETOX has access to large longitudinal datasets of air monitoring, census, epidemiological and biomonitoring studies in urban areas but there is a relative lack of expertise at RECETOX to exploit these datasets’ full potential. Therefore, there is a need to establish a strategic partnership with experienced international partners and global leaders in exposome studies. ISGlobal, UCL and UU will provide and transfer their expertise in investigating the urban exposome. The proposed research will link data on environmental exposures and health outcomes and use advanced statistical and machine learning methods to investigate the impact of the urban exposome on the health of urban populations. Through this strategic partnership, RECETOX expertise will be expended to the areas of environmental health and environmental epidemiology by the combination of collaborative research, education and training activities, junior researcher mobility and support for early stage rese
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Mastering Data-Intensive Collaboration and Decision Making', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

The goal of the Dicode project is to facilitate and augment collaboration and decision making in data-intensive and cognitively-complex settings. To do so, it will exploit and build on the most prominent high-performance computing paradigms and large data processing technologies - such as cloud computing, MapReduce, Hadoop, Mahout, and column databases – to meaningfully search, analyze and aggregate data existing in diverse, extremely large, and rapidly evolving sources.Building on current advancements, the solution foreseen in the Dicode project will bring together the reasoning capabilities of both the machine and the humans. It can be viewed as an innovative workbench incorporating and orchestrating a set of interoperable services that reduce the data-intensiveness and complexity overload at critical decision points to a manageable level, thus permitting stakeholders to be more productive and concentrate on creative activities. Services to be developed are: (i) scalable data mining services (including services for text mining and opinion mining), (ii) collaboration support services, and (iii) decision making support services.The achievement of the Dicode project's goal will be validated through three use cases addressing clearly established problems. These cases were chosen to test the transferability of Dicode solution in different collaboration and decision making settings, associated with diverse types of data and data sources, thus covering the full range of the foreseen solution's features and functionalities. They concern: (i) scientific collaboration supported by integrated large-scale knowledge discovery in clinico-genomic research, (ii) delivering pertinent information from heterogeneous data to communities of doctors and patients in medical treatment decisi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Epithelial cell sheets as engineering materials: mechanics, resilience and malleability', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

The epithelium is a cohesive two-dimensional layer of cells attached to a fluid-filled  fibrous matrix, which lines most free surfaces and cavities of the body. It serves as a protective barrier with tunable permeability, which must retain integrity in a mechanically active environment. Paradoxically, it must also be malleable enough to self-heal and remodel into functional 3D structures such as villi in our guts or tubular networks. Intrigued by these conflicting material properties, the main idea of this proposal is to view epithelial monolayers as living engineering materials. Unlike lipid bilayers or hydrogels, widely used in biotechnology, cultured epithelia are only starting to be integrated in organ-on-chip microdevices. As for any complex inert material, this program requires a fundamental understanding of the structure-property relationships. (1) Regarding their effective in-plane rheology, at short time-scales epithelia exhibit solid-like behavior while at longer times they flow as a consequence of the only qualitatively understood dynamics of the cell-cell junctional network. (2) As for material failure, excessive tension can lead to epithelial fracture, but as we have recently shown, matrix poroelasticity can also cause hydraulic fracture under stretch. However, it is largely unknown how adhesion molecules, membrane, cytoskeleton and matrix interact to give epithelia their robust and flaw-tolerant resilience. (3) Regarding shaping 3D epithelial structures, besides the classical view of chemical patterning, mechanical buckling is emerging as a major morphogenetic driving force, suggesting that it may be possible design 3D epithelial structures in vitro by mechanical self-assembly. Towards understanding (1,2,3), we will combine a broad range of theoretical, co
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Microeconomic Analysis of Prices, Food and Nutrition' (MAPFAN).

assistant: **Concept**

Diet-related chronic diseases are a major public health concern.  Addressing this concern is a key government policy objectives. Poor diet is one important cause, and a number of policies are aimed at improving diet. The impact of these policies on diet, and thus on health outcomes, will depend crucially on how consumers adapt their food purchasing behaviour in response to the policy, and on how firms in turn respond in terms of the prices they set and the foods they offer.  This proposal sets out an ambitious programme of research that aims to provide a deeper understanding of consumer food purchasing behaviour and firm food pricing behaviour, and their impact on nutrition, taking account of the fact that these markets are typified by oligopolistic competition. This research agenda is made possible by rich new household level data on prices and nutrients.  The research will comprise five inter-related projects. The first two projects will develop a set of models and econometric tools which will produce interesting results in their own right, but will also provide key inputs into the other three projects. Each project seeks to make fundamental advances on the existing literature, and addresses an important policy question. The projects are linked since they will utilise related modelling tools, econometric methods and data. Together these projects will provide a more comprehensive analysis of policy options in the area of food and nutrition than would be possible with independent projects. The projects are: estimating demand for food, store choice and nutritional outcomes; estimating income effects; ex ante evaluation of tax policies; ex post evaluation of information campaigns; and innovation, nutrition and the introduction of new products in the food industry.