RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Molecular mechanisms of germ cell migration across the mammalian blood-testis barrier' under Seventh Framework.

assistant: **Concept**

During spermatogenesis, germ cells located in the basal compartment of the seminiferous epithelium of the testis migrate across the blood-testis barrier (BTB) to continue differentiation on the luminal side. This trans-epithelial migration (TEM) requires regular restructuring of junctions present in the BTB. How germ cells pass the BTB, which harbours one of the tightest junctions present in the body, without compromising the integrity of the BTB is poorly understood. Several hypotheses have been put forward, but the mechanism remains unknown. We have recently published evidence for the existence of an intermediate compartment harbouring germ cells in transit across the BTB. This compartment is composed of the tight junction proteins occludin, claudin-3 and CAR. Claudin-3 and CAR appear to be unique to the intermediate compartment since these proteins are not general components of the BTB, and could therefore be used as biological markers. This application is based on these findings. We plan to use several different innovative approaches to uncover mechanisms for TEM and the role of the intermediate compartment in this process. 3D reconstructions of germ cells during TEM will be produced using several imaging techniques including the novel and powerful method of Dual Beam Microscopy. Integrity across the BTB will be analyzed by using tracers of defined size, protein composition of the intermediate compartment will be analyzed using a combination of imaging and gene expression tools and an in vitro model system will be set up using primary cells isolated from testis. Finally, the role of CAR in TEM will be analysed using a conditional CAR knockout mouse that was recently constructed in our laboratory. We expect that results will lead to new insights into mechanisms gover
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Smart Cloud Integrated Development Environment supporting the full-stack implementation, composition and deployment of data-centered services and applications in the cloud'.

assistant: **Objectives**

The main objective of SmartCLIDE is to propose a radically new smart cloud-native development environment, based on the coding-by-demonstration principle, that will support creators of cloud services in the discovery, creation, composition, testing and deployment of full-stack data-centred services and applications in the cloud. SmartCLIDE will provide high levels of abstraction at all stages (development, testing, deployment and run-time) as well as self-discovery of IaaS and SaaS Services. SmartCLIDE will provide several categories of abstractions: at development stage, SmartCLIDE will provide abstractions on data transformations or processing; at testing stage, mechanisms to visualize flow and status or artefacts to automatically test the expected behaviour; at deployment stage, abstractions of physical and virtual resources; or at run-time, mechanisms to monitor the performance and operation of the service.The cloud nature of the environment will enable collaboration between different stakeholders, and the self-discovery of IaaS and SaaS services and the high levels of abstraction will facilitate the composition and deployment of new services to non-technical staff (with no previous experience on programming or on the administration of systems and infrastructure). Equally, hiding the complexity of the infrastructure, and adding intelligence to this layer, will allow to select the most adequate infrastructure services in each moment.SmartCLIDE will allow SMEs and Public Administration to boost the adoption of Cloud and Big Data solutions, being validated at one solution oriented to Public Administration (Social Security System) and three different IoT and Big Data products of software development SMEs within the consortium.


**Keywords:** Cloud Services, Service Ori
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Rural survival strategies in central-eastern europe as a design base for sustainable agriculture' demonstrating excellence, impact and implementation quality for a Fifth Framework call.

assistant: **Abstract**

Survival strategies play an important role in the rural economies of Central and Eastern European countries. They involve informal market circuits, social networks and a specific use of local natural and agricultural resources. They may constitute up to 60% of regional gross production. There is growing worldwide scientific attention for survival strategies, but their socio-economics and agro-ecological potential remains however hardly understood, especially in CEE countries. The identification and strengthening of these survival strategies may provide however important starting points for the design of viable, economically diversified and environmentally sustainable alternatives for rural and agrarian development. This project proposes to bring together qualified research bodies from The Netherlands, United Kingdom, Greece, Romania, Bulgaria and Hungary. The aim of this Accompanying Measure is to organise a workshop to jointly design a larger action-research proposal for submission to a shared cost programme under thematic priority 5.5, Theme 1 (QOL) of the Fifth Framework Programme.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Holographic 3D Display for visualising volumetric images from medical scanners' (HoloMedical3D) under Horizon 2020.

assistant: **Objectives**

Medical imaging technology has been improving at a rapid pace over the past decades with Ultrasound, CT, PET and MRI scanners increasing in performance. This is driven by the need to deliver faster, high quality, efficient and cost-effective healthcare. These machines generate 3D volumetric imagery as a series of 2D slices scanned through the body using radiation (ionising & non-ionising) or ultrasound. These data are presented directly to viewer(s) as full 3D images via the holographic volumetric display. The display essentially performs the inverse operation and converts the radiation into a photonic representation, showing the 2D slices as a series of “light sheets” suspended in free space.Holoxica has pioneered a series of motion holographic video displays over the past few years. The award-winning technology produces excellent results with large, bright images floating in mid-air without the need for cumbersome glasses. The display system comprises state of the art optical components (patented Holographic Optical Element, lasers, high speed projection), embedded electronics and image processing with software. The basic principles have been proven (TRL4/5) in a series of national projects and successful completion of the project will result in a TRL7 prototype validated within realistic medical scenarios.The benefits of the holographic volumetric display include quicker interpretation of 3D scan images, faster surgery and better quality surgical procedures. The breakthrough innovation will meet an urgent demand from medical professionals for a 3D visualisation solution that can match the performance of scanning devices. Applications include teaching/training, diagnostics/planning and live surgery.Medical Imaging 3D Displays is a global $4.3B market by 2020, growing
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Small Signalling Peptides for Stimulating Root Growth - a Novel Approach to Improve Nutrient Use Efficiency' to be submitted under Horizon 2020.

assistant: **Abstract**

Plants in the legume (Fabaceae) family are able to fix atmospheric N2 under N-limiting conditions, thereby diminishing the need for N-fertilization. N2-fixation has a high requirement for photosynthates and ATP, and is thus tightly controlled by both the N-availability in the soil and P-level in the plant. Increasing the P-uptake through formation of branched root system and abundant root hairs will increase the N2-fixing capacity and thereby improve the overall nutrient use efficiency (NUE). Small signalling peptides are a largely un-characterized group of regulatory molecules in plants that induce signal transduction pathways upon binding to their complementary receptor signalling modules. Even in the most studied model plant Arabidopsis thaliana only a few of the more than one thousand putative SSPs have been characterized. Very recent work has revealed unique roles of SSPs in alteration of the root system architecture in response to nutrient availability, including the formation of root hairs under P-limiting conditions. Hence, a deeper understanding of the functional roles of SSPs appears to be of key importance for improving NUE.  This project aims at advancing our knowledge of SSPs involved in the adaptation to nutrient limiting conditions in legumes beyond current state-of-the-art. This will be achieved using a novel bottom-up bioinformatic approach and unique mutant populations. The scientific objectives are (i) to identify the receptor signalling module and the down-stream target genes in the signal transduction pathway of a newly discovered P-responsive SSP essential for root hair formation, and (ii) to discover unknown N- and P-responsive SSPs in the roots and nodules of the legume model species Medicago truncatula with the aim of (iii) investigating the eff
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Smart-grid optimisation using rate of change of frequency (RoCoF) to rapidly balance power grid network frequency - enabling more widespread use of unpredictable renewables and minimising blackouts' (RoCoF).

assistant: **Concept**

Endeco Technologies Ltd is a pioneering, award winning company recognised as the technology leader in smart grid energy aggregation. Our vision is to become the world’s largest fast acting electricity load aggregator, controlling over 350 MW of load and creating Europe’s largest ‘virtual power plant’. This will allow us to grow our company from our current aggregated load of 50 MW, and our turnover of €4.5 million to €43 million per year by 2022.Electricity systems in EU countries are facing significant challenges as penetration of renewable energy (in particular wind) continues to increase to meet ambitious carbon reduction targets. Due to the intermittent and inflexible nature of renewable energy sources, efficient real-time frequency balancing of grids will become a major challenge for grid operators. A deviation of only 1 Hz from the standard grid frequency (50 Hz) can cause blackouts and power outages as the grid loses inertia, requiring grid operators to quickly add/remove load from the grid to restore balance. Following our success with our current smart grid optimisation system we have seen an opportunity to introduce a disruptive new system, OptiGrid, which will use Rate of Change of Frequency (RoCoF) to allow potentially problematic changes in grid frequency to be detected and acted upon within 0.4 seconds, rather than the 10-second state of the art. As well as providing grid security, this will also allow a greater quantity of renewable energy sources to be integrated into the grid as we will be able to effectively and rapidly deliver the required frequency response performance to grid operators.   With the frequency response market expected to see imminent high growth, our technology is well placed to take a significant proportion of this target sector. In t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Development and plasticity of multisensory functions to study the principles of age dependent learning plasticity in humans' (CRITICALBRAINCHANGES), addressing dissemination and exploitation.

assistant: **Impact**

Proposal summary: The present project will investigate the main principles of development and neuroplasticity in humans in the domain of multisensory processes (the interplay between sensory systems). It will be tested how learning plasticity of the human brain changes from childhood to adulthood and how early experience constraints neuroplasticity at later developmental stages as well as in adults. The project is based upon animal findings in sensory development and plasticity. Both a prospective (studies in children) and a retrospective (studies in people with a history of visual or auditory deprivation) approach are employed. Behavioural paradigms from experimental psychology addressing multisensory processes are combined with electroencephalographic recordings (EEG). First, we investigate the functional principles and neural correlates of multisensory development. Second, we investigate multisensory processes in people who suffered from a transient phase of sensory deprivation after birth: (a) in people who were born with bilateral dense cataracts that were removed later, and (b) in congenitally deaf individuals, who were equipped with a cochlear implant to restore hearing. This line of research will reveal the critical contribution of single sensory systems as well as the synchronized input across modalities with regard to the emergence of successful multisensory binding. Third, we will investigate whether it is possible to alleviate neural changes demarcating the end of sensitive phases or critical periods by implementing an incremental training procedure. Last, we will look at whether experimentally induced transient sensory deprivation increases neuroplasticity loss during a sensitive phase or critical period. We are convinced that basic research, such as the pr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Development of highly-efficient low-emission log wood-fired closed fireplace INSERts thanks to an automated elecTRONIC control system' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

RIKA, as one of the European market leaders regarding log wood and pellet stoves, aims at a significant extension of its product portfolio by the development and market introduction of a new closed fireplace insert technology, the INSERTRONIC. With this technology which shall distinguish itself from competing products by significantly reduced emissions, increased efficiency as well as increased user comfort, RIKA will become a complete supplier for wood based room heaters. Thereby, RIKA aims at strengthening its position as European technology leader as well as to double its turnover until 2022. A technical concept of the INSERTRONIC, which builds on RIKA’s innovative log wood stove technology, has already been defined. Within the project the new technology shall be developed, tested and optimised in order to pass type testing at project end. A number of innovations (world-wide novelties for fireplace inserts) shall be implemented, of which the most important are (i) the utilisation of novel insulation materials as well as materials with catalytic coatings for emission reduction, (ii) the application of modern computational fluid dynamics (CFD) simulation tools for process design and optimisation, (iii) the implementation of an automated control and ignition system as well as (iv) the development of a flexible insertion frame and modular panelling system which provide a high flexibility regarding installation and outer appearance. Techno-economic analyses in order to keep the final product costs at a competitive level as well as dissemination, communication and commercialisation measures shall ensure a quick market introduction after project end.Since the European closed fireplace insert market amounts to about 850,000 units/year, the new technology will have asignifica
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Discrete Volume Assembly at Nano-Scale' (DIVAN) targeting Seventh Framework.

assistant: **Abstract**

The objective of DIVAN is to develop a robust, potentially industrially viable process for the discrete assembly of individual Carbon Nano Tubes (CNTs). This competence allows realising devices and applications in which individual CNTs are integrated with micro-scale structures, to provide unique performance or new functions. Applications can be found in sensors, scientific instruments, and a wide variety of nanoelectronic devices like switches. A CNT is a cylindrically shaped nanostructure composed of carbon hexagons. CNTs are grown on a substrate in large numbers using a chemical process. Currently there is no viable method to volume assembly of discrete CNTs. DIVAN aims to rationalise the nano-scale assembly process by developing a set of linkable basic assembly operations. Basic operations include sorting, characterisation, handling and placement of CNTs. The basic assembly operations can be linked together to form complete assembly process chains for bringing CNTs from their fabricated state to their assembled and interconnected state. An essential contribution of the project to the field is the development of an assembly theory for nano-scale assembly. This assembly theory defines the boundary conditions for the assembly operations to be developed, and provides the backbone for structured design and evaluation of nano-scale assembly processes for specific cases. In this way, a systematic engineering and production perspective is added to the predominantly fundamental research oriented field of nanotechnology. Innovative principles for implementing the basic operations will be investigated, including the use of micro-fluidic devices to dispense CNTs, and the use of micro-scale handling structures. A benchmark device, a NEMS accelerometer, will be realised to evalua
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'The World's First Large Scale Cis Based Photovoltaic Installation at the New Museum of Fine Arts in the City of Leipzig' goes beyond current state-of-the-art under Fifth Framework.

assistant: **Innovation**

The City of Leipzig, one of the most famous cities in Saxonia in Germany and internationally well known from its fair, plans the erection of a new building for the museum of fine arts Leipzig directly in the historical centre. The location will be one of the most exposed place in the historical city and will connect the traditional old Leipzig with the city's approach of being the modern, future oriented business city of Saxonia. The innovative building, screened by the Berlin architects Hufnagel, Pütz and Rafaelian shows a South- North orientation and will be equipped with shed roofs which are planed to be covered with app. 50 kW peak FV modules in southern orientation. For the first time worldwide it is planned to install thin film modules based on CuInSe2 (CIS).
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'The evolution of mechanisms that control behaviour' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

The approach to animal behaviour adopted by behavioural ecology is based on the investigation of the adaptive function of behaviour. A common assumption is that the action of natural selection on behaviour can be predicted without reference to processes inside the organism. I believe that it is time to combine an analysis based on evolution with one based on mechanisms, where a mechanism might be psychological, physiological or a combination of both. Animals have mechanisms that need to perform well in changing and dangerous environments. In order to understand the evolution of mechanisms, we need a fundamental change in the sort of models that are analysed. Instead of building complex models of optimal behaviour in simple environments, we need to evolve simple mechanisms that perform well in complex environments. This approach can provide a novel and unified perspective on a range of issues involving decisions by animals, including humans. The main objective of the project is to provide a comprehensive view of behaviour that can account for both adaptive and non-adaptive actions. This involves developing a novel theoretical framework based on an understanding of the underlying information-processing rules, combined with an evolutionary perspective that explains how any such rule came into existence in the first place. The theme of coping with uncertain and dangerous environments is used to investigate various features of behaviour such as rationality and self-control. These topics lead to the broader issues of the organisation of thought and emotions. The project also explores the consequences of the evolved behaviour and the implications for conservation and animal welfare.