RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'sErvitization of Industry X.0 Assets powered by secure, Resilient and immersive digital twin teCHnologies' (EXARCH), addressing dissemination and exploitation.

assistant: **Impact**

Recent EU decisions highlight the need to further invest and innovate in the field of Digital Twin (DT) technologies, targeting at unrestricted monitoring, visualization, simulation and optimization of critical infrastructures, processes, subsystems and industrial processes in a manner that is economically and environmentally sustainable, efficient and flexible. Digital Twins (DTs) constitute the new field of convergence of the biological, physical and digital worlds and form the basis of the twin transition by 2030; yet, their development requires an interdisciplinary view of the main processes that govern the operation of enterprises, to effectively develop and/or embrace new products. Fully-fledged digitization of physical assets in the production field through DTs (i.e., workers, mobile/fixed robots, stock, fleet), constitutes the main vehicle towards the adoption of innovative and emerging business models that distinct the ownership of assets from their daily usage and management, a.k.a. servitization. The EXARCH programme sets the ambitious aim to design, implement and experimentally demonstrate the performance of a fully modularized end-to-end digital twin platform, along with the necessary algorithmic innovations, to support of the emerging Asset-as-a-Service (AaaS) paradigm. The EXARCH DT-enabled platform brings forth the design of cloud-native AaaS microservices that fully leverage the exciting new capabilities offered by 6G mobile data networks as well as state-of-the-art advances in semantics-aware computer vision, aiming to create a resilient and immersive biological, digital and physical Industry X.0 continuum. EXARCH targets to the development of an immersive user-centric service suite designed to automate AaaS management, addressing unique cybersecurity
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Carboxylic acids as REAcTIVE refrigerants to make heat pumps efficient' under Horizon Europe.

assistant: **Concept**

Aiming to contribute to a substantial increase in the sustainability of thermal power plants, heat pumps, and climatization systems, the ERC-StG-REACHER is introducing new working fluids for the thermodynamic cycle underlying these systems. These new fluids are mixtures of dimers “A2” and monomers “A” undergoing a reversible dimerization reaction, A2 ⇄ 2 A, evolving instantaneously and spontaneously in the unit operations of the machine. REACHER has introduced about 200 of these reactive fluids. Among them, the family of carboxylic acids (e.g., formic, acetic, propionic acid) seems very promising as working fluids for residential heat pumps: other than owing excellent environmental properties, their use promises an outstanding 17-43% relative efficiency improvement compared to state-of-the-art heat pumps. In this context, the main objective of the ERC-PoC-CREATIVE is to perform the first step towards the realisation of a residential heat pump prototype operating with formic acid, enabling the validation of the -theoretically observed- positive chemical reaction effects. This step consists of preliminary verifying the feasible compression of formic acid with a finely controlled series of available compression technologies, using air as working fluid in the sub-atmospheric pressure conditions characterising operation with formic acid. Within CREATIVE, these results will further allow the design of a pilot operating with formic acid to test, in a future PoC, the compressors preliminarily selected and pre-tested with air, in CREATIVE. The realisation and design of the experimental setups for the formic acid compression feasibility assessment are supported by thermodynamic calculations carried out in CREATIVE, using tools developed in REACHER. This PoC is supported by the ex
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Sixth Framework proposal on 'Entrainment of the circadian clock'.

assistant: **Innovation**

The circadian clock is a basic biological process that enables organisms to anticipate daily environmental changes by adjusting behavior, physiology and gene regulation. It impacts health and quality of life in regulating sleep and well-being, in the consequences of shift-work, in medical diagnosis/therapy, and in age-related changes.A critical feature of the clock is its synchronization to the external day (entrainment). Entrainment is the key to understanding the circadian clock and its control mechanisms. In EUCLOCK, highly competitive European researchers join forces to investigate the circadian clock under entrainment using the most advanced methods of functional genomics and phenomics comparing powerful genetic model organisms (humans, mice, flies, and yeast).Its four major innovations will shape the future of circadian research:- To compare genomic and phenomic aspects of the clock, SOPs will be developed for the first time that mimic aspects of the natural day (dawn/dusk, day-lengths, etc).- Protocols, devices and algorithms will be developed, enabling for the first time large-scale, non-invasive research on human entrainment in the field.- Developing the first animal models for shift-work, making animals 'work' and feed out of phase with their natural rhythms. The ensuing dys-entrainment" will be investigated at all levels, aiming to provide the insights needed to treat the symptoms and consequences of human shift-work.- Building on genome sequences, new genetic components and interactions will be identified that control the circadian clock and its entrainment.For the first time the experimental advantages of yeast will be extensively used. The tractability of yeast permits integration and reconstruction of elements and interactions gleaned from other systems.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'The motor hypothesis for self-monitoring: A new framework to understand and treat metacognitive failures'.

assistant: **Innovation**

Humans can monitor their own mental lives and build representations that contain knowledge about themselves. This capacity to introspect and report one’s own mental states, or in other words “knowing how much one knows”, is termed metacognition. Although metacognition is crucial to behave adequately in a complex environment, metacognitive judgments are often suboptimal. Specifically for neurological and psychiatric diseases, metacognitive failures are highly prevalent, with severe consequences in terms of quality of life. This project proposes a new hypothesis to explain the determining factors of metacognitive failures: namely, that metacognition does not operate in a vacuum but relies on the monitoring of signals from the body, and more specifically, on motor signals involved during action execution. We suggest several experiments to test the motor hypothesis for self-monitoring, and propose a new remediation procedure to resolve metacognitive failures resulting from deficient action monitoring. We will start by assessing the contribution of motor signals to metacognition by identifying the behavioral and neural correlates for detecting self-committed vs. observed errors (WP1), and by using virtual reality and robotics to probe metacognition in a vacuum, operating in the complete absence of voluntary actions (WP2). Finally, we will use these results to develop and evaluate a method to train metacognition in healthy volunteers and individuals with schizophrenia in a bottom-up manner, using online feedback based on motor signals (WP3). This new metacognitive remediation procedure will be performed both in a clinical context and on mobile devices. The goal of this ambitious project is therefore twofold, theoretical in shedding new light on a cognitive process central to
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'GrowSmarter' (GrowSmarter).

assistant: **Innovation**

GrowSmarter aims to:• Improve the quality of life for European citizens by better  mobility, housing and the quality of urban infrastructure while improving the citizens economy by lower energy costs and creating as much as 1500 new jobs (on the demonstration level).• Reduce the environmental impact by lower energy needs by 60 % and increased use of renewable energy thus reducing GHG emissions even more.• Create sustainable economic development by demonstrating and preparing a wider rollout of smart solutions.GrowSmarter will demonstrate at 3 lighthouse cities 12 smart, integrated solutions as a way of preparing for a wider market rollout. These solutions are integrated in specially chosen sites making demonstration easy to reach and take part of for the 5 follower cities and other European and international study groups. All the smart solutions are fit into the Lighthouse-cities strategic development plans and the follower cities replication plans. The solutions solve common urban challenges such as:• Renewal of existing buildings. GrowSmarter demonstrates  the cost efficient renewal of  100.000 square meters of Nearly Zero or low energy districts reducing energy demand by 70-90%, • Integrated infrastructures for ICT, street lighting, smart grids district heating and smarter waste handling• Sustainable urban mobility for both passenger and gods integrated in smart grids, biofuels from household waste thus reducing local air quality emissions by 60%.The integration of Cities, strong group of industrial partners together and quality research organisations guarantee that the solutions will be both validated by independent research organisations and transformed into Smart Business Solutions by industry for the wider rollout to Europe. Growsmarter builds on integrated, clos
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Coherent control of spin chains in graphene nanostructures' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

Elementary nuclear and electronic spins are called to be key components in the second quantum revolution. Their atomic-scale integration into scalable platforms with tunable interactions is a demand that I will address in CONSPIRA by synthetizing graphene architectures with interacting spin chains, using customized on-surface reactions of organic precursors, and by controlling their quantum state through microwave spectroscopies.                 I envision the formation of collective magnetic states through the assembly of interacting electronic and nuclear spins in periodic arrays with atomically precise spacings. Through rational design and synthesis strategies, we will tune spin interactions via the graphene host and hyperfine coupling, with the goal of bringing the quantum state of the arrays into different regimes of energy, coherence, and topology.   To access the broad energy range of such multiscale interacting system and to probe its quantum dynamics, we will combine two antagonist experimental techniques like Scanning Tunnelling Microscopy (STM) and Cavity Quantum Electrodynamics (QED). This will be realized by incorporating superconducting coplanar waveguide resonators (CWRs) as substrate of a low temperature STM. We will use QED techniques to couple the resonant states of spin chains with microwave photons of the resonator, while the STM tip acts as a local gate. The MHz and picometer resolution of this new type of spectrometer will enable us to study the quantum coherence of the spin arrays and undertake the coherent control of distant nuclear states entangled through the electronic spin system, a potential system for QED-based quantum computation. CONSPIRA will provide a new platform for quantum spins, and methods to address and manipulate their coherent s
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Rapid absorption denaturalized collagen dressings' (NATURALSKIN), addressing dissemination and exploitation.

assistant: **Impact**

The World Health Organization and United Nations issued a warning statement on the world’s health in September 2011 on hard to heal wounds as 2-3% of world population is expected to suffer severe wound in life. Estimated cost of treating chronic wounds is between 2-3% of annual healthcare budgets (treatments and hospitalization). Essential part of the wound care treatment (after removal of devitalized tissue) is the use of dressings to promote autolysis and reduce microbial presence. EKOLBER has developed a rapid absorption linear (denaturalized) collagen made wound dressing (called NaturalSkin). This solution allows to improve dressings healing characteristics (due to rapid and complete absorption of the matrix) and reduction of dressing application times with a remarkable low price. Those improvements will contribute to reduce hospitals wound care costs and effectivity considerably.The advanced wound dressing market is an enormous and growing market because the number of patients suffering from hard to deal and chronic wounds. Main factors driving the appearance of this kind of wounds are the diabetes, cardiovascular diseases and the aging. Taking into account Natural Skins benefits, market needs and enormous existing market, a clear business opportunity for EKOLBER is outlined.In this Phase 1 project, a feasibility study will be held to analyse the viability of the whole project, analysing market, product, business and financial features in order to guarantee the profitability of the investment in the identified markets and future scenarios.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'New technologies for weight reductions of utility vehicles' in the context of a Fourth Framework call.

assistant: **Objectives**

The project deals with new technologies for weight reductions of utility vehicles. The RTD goals of the project are: * new forming technologies * optimised design by load and stress simulations * substitution of conventional materials Important working fields are: * Selection of vehicle components * Load and stress simulations by FEM * Metal forming technologies * Integration of functional features into structural parts * New steel semi products and structural shapes * Aluminium components * Polyner material and composites
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Low-toxicity copper chalcogenide semiconductor nanocrystals' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

The objective of the present project is a development of approaches for facile colloidal synthesis of Cu-containing semiconductor nanocrystals, characterized by low production cost, high stability, high photoluminescence efficiency and low toxicity. The materials that will be synthesized will undergo comprehensive physico-chemical characterization including a deep assessment of their toxicity and will be evaluated as light absorbing components for fabrication of excitonic solar cells.Copper chalcogenides represented by binary, ternary and quaternary compounds, like CuS(Se,Te), CuIn(Ga)S(Se,Te), CuZnSnS(Se,Te) are one of the most attractive series of low-toxic semiconductor materials, which are truly alternative to the widely studied cadmium, mercury and lead chalcogenides. This new generation of semiconductor nanocrystals is now being in the focus of a great scientific interest. These nanocrystals are characterized by tunable visible and near infrared emission and absorption properties and high extinction coefficients and therefore hold great promise in bio applications, in light emitting diodes fabrication, photovoltaics and optoelectronics.This project will provide new knowledge into the mechanisms governing the reactions involving the various precursors during the stages of nanoparticle nucleation. This new knowledge will then allow for a proper control of nanoparticles crystal structure, composition, size, shape, and consequently of their optoelectronic and photovoltaic properties. The synthesized and fully characterized copper chalcogenide nanoparticles will be used for fabrication of solar cells. Combination and adaptation of state-of-the-art approaches as well as creation of novel synthetic methods will result in innovative investigation covering wide range of ta
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Towards a mechanistic understanding of mRNA localization' under Seventh Framework.

assistant: **Concept**

The localization of mRNAs has been increasingly recognized as a prominent mode of regulation of gene expression in eukaryotes. Localized RNAs can have crucial roles during animal development, in the maintenance of cell polarity and in nervous system function. Studies of RNA localization in model organisms have revealed many components of the process, some of which are conserved across eukaryotes. The correct cytoplasmic localization of mRNAs and their transport and silencing in messenger ribonucleoprotein particles (mRNPs), is dependent on the earliest steps of mRNA processing in the nucleus. The core nuclear mRNP particles associate with further components in the cytoplasm, forming large and dynamic multimolecular assemblies, underlying the various steps or mRNA maturation, transport, silencing and eventual localized translation. Even though many components of these large mRNP particles are known, their detailed molecular organization and regulation is poorly understood. Our aim is to gather structural information of mRNP complexes involved in RNA localization in the fruit fly Drosophila, currently the best-studied model system. We will use a multidisciplinary approach, combining biochemistry, protein crystallography and fly genetics, to tackle the complex structure-function relationships regulating mRNA localization. Our work will elucidate the structural details and molecular mechanisms of how mRNP complexes regulate mRNA localization during development. Given that mRNA localization is a conserved process, our results are expected to elucidate the mechanistic and structural details of a conserved regulatory pathway with fundamental and often medically relevant roles in the cell.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fifth Framework proposal on 'Reaction dynamics: experimental and theoretical studies on the dynamics of reactions of atoms and radicals of fundamental and pratical importance'.

assistant: **Innovation**

One of the main future strengths of Chemistry lays its application to biology, and it is essential for Europe to be able to call on a strong nucleus of trained personnel capable of operating comfortably in this interdisciplinary area. The Network will operate in precisely this area. ENDEVAN will bring together leading groups in the several central relevant areas to train young scientists to think and work across the boundaries of conventional disciplines. Industry has a special need for researchers witch receive will be the acquisition of new skills by working in the laboratories of Network members. The amin formal Training Programmes will be based on regular Network Meetings and the specialised workshops, which will offer lecture presentations and practical training in specialist areas of Network activity. Young researchers will be expected to present their own work regularly in an informal but professional way, thus acquiring this essential skill as an integral part of a their training. A third activity, which will be made available to all young researchers appointed within the Network, is an exchange period spent working on Network research in the laboratory of another member. This is one of the most efficient and natural ways of inculcating new skills."