RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'EUROPEAN NETWORK FOR ALTERNATIVE TESTING STRATEGIES IN ECOTOXICOLOGY' under Seventh Framework.

assistant: **Concept**

EUROECOTOX is a Coordination Action which aims at supporting and accelerating the development and use of alternative ecotoxicology methods and strategies in Europe in order to reduce or replace the use of laboratory animals, particularly those used for regulatory testing. For this, a network will be created (EUROECOTOX network) formed by European R&D groups from universities, public research institutions, animal welfare organizations, specialized ecotoxicological laboratories, industry and other stakeholders, developing alternative test methods.EUROECOTOX network will promote the cooperation between research centres, industry and other stakeholders in Europe devoted to the R&D and application of alternative ecotoxicity methods. It will aim at the integration of efforts and the exchange of knowledge, data and expertise between partners to accelerate the R&D, and validation of new methods. Planned activities includes: Mapping of European research capacities on alternative ecotoxicological test methods, identification of the rate-limiting steps to reduce or replace the use of animals, identification and promotion of new alternative methods, recommendations for future research, promotion of the dialogue with validation agencies and other coordination and networking activities. Elaboration of different documents and publications and launching a dedicated website is also planned. A final Conference open to all the stakeholders, will be organized to disseminate the results. Networking with ongoing activities of other European projects supporting R&D on alternative methods and with other relevant international, European and national R&D and initiatives is also expected.This Coordination Action will be carried out over two years by a consortium composed of eight partners with co
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Bioorthogonal Implantable Iontronic Switch to Temporally Control the Local Release of Chemotherapeutics' (2021-2027).

assistant: **Innovation**

Our vision for a new type of cancer treatment is based on an implantable therapeutic system capable of ‘programmable’ on-demand delivery of drugs directly to the tumor. We conceive an implantable iontronic switch (bioSWITCH) to enable a spatiotemporally controlled administration of highly potent chemotherapeutics, without the need for systemic administration of (pro)drugs or drug conjugates.This radically new technology will be realized by a combination of next-level tools. As a result, bioSWITCH can generate previously unobtainable discrete as well as continuous drug concentration profiles at the tumor site, and thus allows for the use of highly potent drugs that are otherwise not applicable due to high cytotoxicity. The goal is to demonstrate the technology’s potential to effectively interfere with tumor progression using a xenograft pancreas cancer mouse model. Efficiently shrinking tumors in size allows for surgical resection of previously non-operable tumors and dramatically increases survival rates.Our consortium of world leading academics and pioneering SMEs will ensure the translation of this disruptive technology into the market to maximize the socioeconomic impact.


**Keywords:** bioelectronics, drug delivery, pancreatic cancer, bioorthogonal tools, implanted devices, iontronics
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Avant-garde R&D platform and demonstration plant towards efficient industrial biotechnologies' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Within the last years, the consumer’s trends have massively been turning away from artificial and petrochemical additives in favour of natural equivalents considered as healthier and eco-friendlier. In this context, facing traditional methods such as chemical synthesis (requiring toxic products and energy craving) or extraction from natural sources (usually at high cost, with high social/environmental toll), biocatalytic routes are intensively studied as alternative for the synthesis of molecules. Biocatalytic processes, that use natural catalysts such as enzymes or microorganisms, are considered as the most promising way to produce numerous chemicals. Nevertheless, due to several technical and financial intrinsic barriers, biocatalysis struggles to go out from laboratories and conquer the century-old chemical industry outside of the high added-value pharmaceuticals field. Since its creation in 2003, the spirit of NATURAMOLE, technology-driven biotechnology company, has been to address the need for eco-friendly products and processes by the formulation industry. Coupling a R&D platform and a demonstration plant, our project, called the Green Factory, aims at leveraging 15 years of successful R&D on enzymatic esterification and its industrialisation to broaden the scope of application of our novel biotechnologies towards new target markets with higher volumes and lower prices. Through our unique enzymatic technology, we propose to accelerate the industrial transition from polluting chemistry to a more sustainable model conciliating cost-efficiency and environmental performance. Today, NATURAMOLE presents a consolidated commercialisation roadmap to address the needs of the flavours and fragrances industries. With Green Factory, we expect to expand the scope of biocatalyti
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'The impact of early life infections on non-communicable diseases'.

assistant: **Concept**

A number of associations confirm that a broad spectrum of non-communicable diseases (NCDs) can stem from infections, but evidence remains limited. Of particular interest are infections that occur during vulnerable early life stages, as they hold the potential to trigger developmental adaptations of various organ systems with life-long consequences. The ""Early Life Infections and NCDs"" (ELIaD) project aims to elucidate the role of early life infections on NCDs development by bridging existing data on infections with information on NCDs and their intermediate phenotypes in children across Europe. Leveraging the extensive resources of the EU Child Cohort Network, ELIaD will use existing harmonized prospective data on neurodevelopmental, cardiometabolic, and respiratory health outcomes linked to major NCDs. Simultaneously, the project will pioneer with the development of harmonised variables on infections in the child-cohorts that is currently lacking. Detailed prospective information on sociodemographic, lifestyle and environmental characteristics will be integrated to assess confounding, mediation and effect modification of the associations. Analyses will particularly take into account specific age windows of susceptibility. The project will create and disseminate new knowledge on links between early life infections and NCDs in children and will identify vulnerable groups. A key output of ELIaD will be the creation of a large open dataset on infections and NCDs in children, which will allow further investigation of causal links (e.g. with gastrointestinal diseases), in-depth investigations into the underlying mechanisms and the extension of evidence into adulthood. The outcomes of this research will play a vital role in shaping public health policies geared towards the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Towards sustainable global food safety collaboration' under Seventh Framework.

assistant: **Concept**

Guaranteeing the long term availability of safe foods is a global concern that has initiated a large number of activities, including research, policy development and implementation, legislation and training. Extensive information is generated about food safety, but it is fragmented, and not internationally disseminated. The Collab4Safety consortium will establish a global network on food safety with the aim of developing a sustainable coordination platform for exchange of food safety information about research findings, capacity building and policies and facilitate the control and mitigation of existing and emerging food risks. Tried and tested methods will be used to identify problems and gaps in knowledge, resulting in generation of outputs valuable to research managers and interested stakeholders globally. Establishing a permanent structure will contribute to the development of trust between key players and institutions, which is needed to create an international forum for exchange of information and opinions on matters pertaining to food safety in the food and feed chain
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Glocal enterprise network focusing on customer-centric collaboration' in the context of a Seventh Framework call.

assistant: **Objectives**

GloNet aims at designing, developing, and deploying an agile virtual enterprise environment for networks of SMEs involved in highly customized and service-enhanced products through end-to-end collaboration with customers and local suppliers (co-creation). GloNet implements the glocal enterprise notion with value creation from global networked operations and invol¬ving global supply chain management, product-service linkage, and management of distributed units.In specific it aims to: (i) develop a novel way to commonly represent/provide information and knowledge (e.g. catalogue of products, brochures, process descriptions, best practices, company profiles, etc.) which needs to be shared/exchanged among different stakeholders in the collaborative environment as dynamic software services that may upgrade in time; (ii) generate user-customized interfaces which is adjustable to different stakeholders, supporting their access and visualization needs; (iii) provide these services through the cloud, to be available to anybody, at any time, from anywhere,  (iv) demonstrate how a broker in very close contact with the customer who gives an order, can iteratively retrieve all needed information to step by step design the customer order and finally presenting the solution that is accepted by the customer, (v) support the negotiation among all involved parties, (vi) generate a workflow from the accepted/negotiated solution, which will then be automatically monitored, while also available for monitoring by the involved stakeholders, during its execution.The guiding use case is focused on the deployment and maintenance and life cycle support of solar parks. GloNet results are expected to bring major improvements in production and product life cycle support processes shortly after the c
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Arctic Tipping Points' under Seventh Framework.

assistant: **Concept**

The broad interdisciplinary consortia assembled in the Arctic Tipping Points (ATP) project will be managed (WP1) to identify the elements of the Arctic marine ecosystem likely to show abrupt changes in response to climate change, and establish the levels of the corresponding climate drivers inducing the regime shift for these tipping elements. ATP will evaluate the consequences of crossing those tipping points, and the associated risks and opportunities for economic activities dependent on the Arctic marine ecosystem. Historical records of Arctic climate change and projections of future changes in Arctic sea climate and ice systems are compiled (WP2), and time series of Arctic ecosystem components analysed using novel statistical tools to detect regime shifts and ecological thresholds and tipping points, and evaluate their sensitivity to climatic forcing (WP3). Experimental manipulations and comparative analyses across broad climatic ranges will be used to detect climatic thresholds and tipping points of Arctic organisms and ecosystems, using genome-wide analyses to develop genomic markers of climate-driven stress useful as early-warning indicators of the proximity of tipping points (WP4). A biological-physical coupled 3 D model will be used to generate future trajectories of Arctic ecosystems under projected climate change scenarios and to identify their consequences for the Arctic ecosystem (WP5). The impacts of abrupt changes in the Arctic ecosystems for activities of strategic importance for the European Arctic and the associated impacts on employment and income will be elucidated, and policies and legislative frameworks to adapt and mitigate these impacts will be analysed (WP 6). The effectiveness of possible alternative, post-Kyoto policies and stabilization targe
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Energy Efficient Tunnel FET Switches and Circuits' in the context of a Seventh Framework call.

assistant: **Objectives**

E2SWITCH focuses on Tunnel FET (TFETs) as most promising energy efficient device candidates able to reduce the voltage supply of integrated circuits (ICs) below 0.25V and make them significantly more energy efficient by exploiting strained SiGe/Ge and III-V platforms, with CMOS technological compatibility. A full optimization and DC/AC benchmarking for complementary n- and p-type TFETs, integrated on the same fabrication platform, is proposed. Compact models are developed and implemented in Verilog A, for portability, to support the design of low power ICs with CMOS architectural compatibility for: (i) digital and (ii) analog/RF. The device scalability, operational reliability and the operation from room to high temperature, as required by ITRS metrics, are priorities of our investigations. In order to push even more the III-V and SiGe/Ge TFET performance we propose to study, optimize and experimentally validate new device concepts such as a Density-Of-State (DOS) switch exploiting the effect of dimensionality. The DOS switch will deliver deep subthermal switching (subthreshold swing less than 10mV/decade, for at least four decades of current).An advanced TCAD simulation platform is developed for the selected material systems, able to capture quantum effects and to accurately predict the influence of dimensionality. TCAD will also support the optimization of TFETs on the two proposed material platforms, with emphasis on the role of strain and on the alignment between the tunneling path and the electric field.A full set of characterization techniques including DC, AC, low frequency noise, RF measurements (S-parameters) and large range of temperature is foreseen to support the device optimization, parameter extraction and the calibration of the compact models.We will deli
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'Magic development process improvement'.

assistant: **Concept**

This project is designed to improve the software testing methodology of Magic Software Enterprises Ltd. It is part of an overall process to raise the level of development technology from level one on the SEI CMM scale to level two. Magic's business is related to the provision of application development tools supported on a very wide range of platforms, OS and networks and interfacing to many different Data Base Systems. The principal product of the company is the Magic applications development tool which is an interactive, GUI form based system that is sold world wide to a broad range of customers. The effectiveness of the software testing activity is to ensure forward compatibility without regression. The objectives are to increase test coverage by 25%, to improve stability by 25%, to reduce QA (Quality Assurance) cycle time by 15% and improve reliability by 20%.In order to reduce the cost associated with the production and maintenance of each new system version and variant, we need to improve the efficiency and effectiveness of our software process by the use of a automated and comprehensive test environment. The results of an external review of our processes has recommended the adoption of an integrated test management system as an essential step in achieving our quality goals.THE EXPERIMENTThis 12 month PIE will enable us to complete the final selection of a suitable test tool set, its integration into the environment and its trial use of in a typical development project. The baseline project is planned to be part of a release of MAGIC Version 8 that will include expanded capability in handling of Web connectivity. In the PIE, the DB Gateway part of the product will be re-tested using new automatic procedures and compared to the current manual method.In addition to
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Self-sustaining vibration and mechanical resonance effects in stimuli responsive liquid crystal polymer coatings and membranes (Vibrate)' to be submitted under Horizon 2020.

assistant: **Abstract**

The amplification of collective molecular effects to macroscopic deformation is one of the most intriguing challenges  in materials science. Individual molecules can be reversibly activated by various means such as light, chemicals and external electrical or magnetic  fields. They may respond  by changing their orientation, their molecular conformation or by breaking /forming chemical bonds. Bringing these molecules in a matrix of an ordered molecular system, such as a liquid crystal polymer network, introduces molecular cooperativity and directionality. Dimensional changes of the individual molecules add up to large effects such as the formation of deformed surfaces in a coating and the formation of free volume (molecular voids) in membranes. The objective of the present proposal is to bring the molecular action, in conjunction with the macroscopic deformation, out of its equilibrium aiming a self-sustaining oscillation of the macroscopic response to a continuous trigger.  An example that will be investigated is a surface that continuously changes it topography when addressed by its trigger. Another example is a membrane that will oscillate its (localized) free volume thus providing an active transport mechanism for species through the membrane. Alternatively we will investigate the response to an oscillating trigger with a frequency matching the molecular action to find sweet spots for mechanical resonance thus enhancing the macroscopic effect. The research is challenging. Only, with a comprehensive and combined effort, we can expect the required progress needed to close the gap between materials science, optics, electronics and mechanics and to deliver routes to new applications. But when achieved it will undoubtfully lead to new applications in coating and film tech
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Adaptive Risk Cultural Heritage Assessment In Conservation' (ARCHAIC).

assistant: **Concept**

The current project, ARCHAIC (Adaptive Risk Cultural Heritage Assessment In Conservation), aims to provide a new intelligent methodfor the risk management of heritages. In ARCHAIC, I plan to recognize physical deterioration and degradation evolution inmonuments by computer vision methods (using a combination of Neural Radiance Fields (NeRF) and social media imagery) and usethem as inputs to assess the degree of vulnerability via the neuro-fuzzy method. To compare social media photos captured at varioustimes for detecting changes, deterioration, and achieving deterioration growth, I encounter the challenge that the images vary incamera. By reconstructing 3D models of monuments at various times via NeRF and comparing images, we can effectively identifychanges and deterioration over time. Camera pose estimation is performed using Inerf, a deep neural network-based methodspecifically designed for accurate camera pose estimation of social media images. The estimated poses are utilized and given to theNeRF models to generate pair comparison viewpoints for image analysis. Finally, I consider detected deterioration’s type, boundary,amount, and growth for the fuzzy rules. ARCHAIC leads to determining the amount of intervention to manage the risks of a querycase of a monument.


**Keywords:** Cultural heritage, Artificial intelligence, Conservation, Risk assessment