RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Clinical validation of an antibiotic-resistant bacteria global vaccine platform through the first vaccine against Klebsiella pneumoniae'.

assistant: **Innovation**

VAXDYN, a Spanish biotech startup, is leading innovation with a novel vaccine platform targeting antimicrobial-resistant (AMR) infections, a critical global health threat. With projections indicating a potential cost of USD 100 trillion and over 10 million deaths by 2050 due to AMR, VAXDYN's work is of paramount importance. Their patented technology focuses on the most dangerous AMR bacteria, developing vaccines for four out of the six most urgent bacterial pathogens, which are responsible for 73% of AMR-related deaths worldwide.VAXDYN's vaccine platform stands out for its utilization of full Outer-Membrane Protein bacterial antigens with a safe carrier cell to stimulate immunity. This unique strategy has earned approval from European regulators and prestigious backers such as the CARB-X accelerator, funded by entities including the Bill and Melinda Gates Foundation and the Wellcome Trust.The company's lead vaccine, K-VAX, targets Klebsiella pneumoniae, the third leading cause of AMR deaths, claiming 700,000 lives annually. There are no current vaccines against this pathogen, which has a mortality rate exceeding 50%. VAXDYN's K-VAX aims to serve both the global elderly population and prevent neonatal sepsis in low-and middle-income countries, addressing a potential $6 billion market by 2035.VAXDYN is advancing K-VAX through Phase 1A trials, supported by CARB-X and private investors. The next steps involve Phase 1B and Phase 2 trials to determine the final formulation and efficacy, for which EIC funds are crucial. Post-trials, VAXDYN plans to license K-VAX, continuing the development of its second vaccine, P-VAX, for Pseudomonas aeruginosa infections in patients with chronic respiratory conditions. This strategic move underscores VAXDYN's commitment to addressing urgent
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Multilingual sentence processing in real-time' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

The project INSPIRE (multilINgual Sentence Processing In Real-timE) will investigate two potential factors that influence multilingual sentence processing, cross-linguistic influence and language dominance, to shed light on the ongoing debate about how the language systems in a multilingual speaker's mind/brain interact. We will employ two time-sensitive methods, eye-tracking and mouse-tracking, to investigate how German native speakers living in Norway and non-native speakers of German whose native language is Norwegian process German case marking in different sentence structures (transitive structures, ditransitive structures); the findings will be compared to those obtained from a group of German native speakers in Germany. The language combination was chosen because it enables us to test whether the groups differ in how they use morphological case and word order to identify who did what to whom in a sentence. Unlike German, Norwegian has no morphological case on full noun phrases, but mostly relies on word order for sentence interpretation. Our experimental design not only enables us to investigate whether non-native speakers are affected by cross-linguistic influence from theirfirst language (Norwegian) when processing German (and rely more on word order than case), but also how a change in language dominance affects sentence processing in German native speakers, i.e., whether they show a processing pattern that is more similar to that of the non-native group after longer exposure to and usage of Norwegian. Thus, unlike previous studies, INSPIRE will reveal whether cross-linguistic influence is bidirectional. The project will fill a gap in current research on language attrition by investigating real-time processing and will inform us how the lack of input and use c
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'FS-UNIT: Light-weight, portable medical Field Suction Unit to disrupt the pre-hospital market' (FS-UNIT), addressing dissemination and exploitation.

assistant: **Impact**

Excitus is an award-winning high-tech health start-up set to disrupt the pre-hospital emergency care market by providing a lightweight, easy-to-use, instantly functioning portable medical suction device. Sudden out-of-hospital cardiac arrests remain are highly lethal, with 9 out of 10 of the 350,000 EU cases ending in death. When a person’s heart stops, fast response is needed. Many times, fluid such as vomit clog up a person’s airway during a cardiac arrest, and so it is standard practice for ambulances to carry suction devices to clear airways. Prompt airway clearing can increase survivability in trauma cases by as much as 10%, yet current portable suction devices are not designed with a paramedic-centric view. Instead, they are heavy, bulky, difficult and time consuming to use, requiring both hands for operation and extensive cleaning afterwards. Resultantly, paramedics do not carry them to the scene at first response, thereby compromising the patients’ lives. Having worked for the world’s largest supplier of emergency care pre-hospital medical devices for decades, we were disappointed by the lack of innovation and user-centric design. We imagined a scenario were paramedics would enjoy using portable suction devices. After widely consulting with paramedics, physicians and Emergency Services operators, we created a completely new handheld design applying advanced mechatronics to deliver a suction device that is 85% lighter than current products whilst achieving the required life-saving performance. We have received the support of the largest private ambulance providers in Europe and the US and are currently creating a global distribution network. The market for medical suction devices is growing to just under €1bn by 2024 with one of the key drivers being the demand f
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Conquering New Frontiers in Conceptual Density Functional Theory: Going Beyond the Single Slater Determinant.' to be submitted under Horizon 2020.

assistant: **Abstract**

Although it is much newer than orbital-based approaches, conceptual density functional theory (CDFT) has established itself as an important tool for understanding the properties and chemical reactivity of molecules and materials. Until now, CDFT has been mainly applied using single Slater determinant (single-reference) quantum chemistry methods, chiefly Kohn-Sham density functional theory. In contrast to orbital-based interpretive tools, however, this is not an intrinsic limitation of CDFT: the response functions that are used to clarify chemical phenomena in CDFT are equally applicable to accurate multireference methods like traditional complete active space self-consistent field (CASSCF) approaches and new, more efficient, approaches based on the density matrix renormalization group (DMRG) or geminal-product wavefunctions. This research proposal combines recent progress in these two fields: new methods will be developed for computing CDFT’s response functions using accurate multireference wavefunction methods. This development will allow the well-known and widely-used reactivity descriptors like the Fukui function and the linear response to be applied to systems—like (bi)-radicals, transition metal-, lanthanide-, and actinide-complexes—where traditional orbital-based methods and previous computational approaches to CDFT based on a single Slater determinant are inapplicable. This will provide chemical insights into the reactivity of new classes of molecules. In addition, by using the linear response function to evaluate alchemical changes in molecular decomposition, the inverse design problem (designing molecules with specified properties) will be addressed. This establishes a new research niche at the nexus between modern interpretative tools, the latest developments
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Study of local environment and microscopic motion of protons in yttrium doped barium cerate by neutron diffraction, neutron scattering and microscopic simulation' (PROCOMAL).

assistant: **Concept**

Alarming environmental concerns and the decline of supply of relatively cheap crude oil in the next decade signal an end to the era of fossil fuel utilisation for energy production and call urgently for revolutionary advances in alternative energy sources . Among other possibilities hydrogen is the ideal fuel and fuel cells are one of the most attractive energy conversion devices. The major research and development obstacles are the high cost in catalyst loading, corrosion and poisoning of electrodes and components and severe demands on electrolyte properties. Our proposal focuses on a neutron-scattering study joint to atomistic modelling of the proton dynamics in yttrium-doped barium cerate (BCY), a solid electrolyte. Further step is the interaction with a team of fuel-cell prototyping and testing. BCY is known for its high protonic and low electronic conductivity at ~800°C, a temperature acceptable for industrial power generation to onboard vehicle applications and suitable for fuel-cell operation without noble metal catalysts. Our experimental approach builds on the exceptional sensitivity of neutrons to hydrogen (via incoherent scattering) for proton-diffusion study and the high contrasts among the elements in BCY (via coherent scattering) for structural characterization of the system. We propose to use 1) the QENS spectrometer (IPNS-ANL) for its unique capability of concurrent data collection of diffraction and quasi-elastic to elastic scattering, 2) the pulsed-source chopper spectrometer HRMECS (IPNS-ANL) for access to the high energy transfer range to probe the phonon and local modes involving hydrogen and 3) MIBEMOL multi-chopper spectrometer (LLB) for its high energy-resolution and neutron flux for detailed quasi-elastic scattering. The proposed wor k aims at t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Analysis of regulatory T cell proliferation and apoptosis in vivo at the cellular and molecular level'.

assistant: **Concept**

Foxp3+ regulatory T cells are critical for controlling the degree of immune activation during infection, autoimmunity and allergy. Despite the importance of this cell lineage to human health, relatively little is known about the molecular and cellular control of their differentiation and homeostasis. In order to rectify this deficit we propose to investigate the properties of proliferation and apoptosis during expansion, contraction and homeostatic stages, using sophisticated genetic models. We will also investigate the role of Bcl-2 family member genes and the IL2 / Pdl1 axis in the molecular control over these cellular properties. By dissecting the factors controlling regulatory T cell numbers we ultimately seek routes to make this process amenable to therapeutic manipulation.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'a.r.t.e.s. EUmanities - European Graduate School for the Humanities Cologne'.

assistant: **Concept**

artes EUmanities offers a doctoral programme (DP) with a mandatory mobility phase, as part of the established artes Graduate School for the Humanities Cologne (AGSHC). Designed around the needs of each individual Early Stage Researcher (ESR) in the Humanities, it will provide places for up to 10 ESRs every year for 3 years.EUmanities relies on a structured but flexible bottom-up approach, providing an interdisciplinary DP for the entire Humanities that supports ESRs to design their own individual research and career development. Thanks to a wide-spread network of regional, European and global networks of excellent research, academic and intersectoral partner organisations, they will learn to work discerningly and decisively, think and engage beyond disciplinary, national and sectoral boundaries.artes EUmanities will be implemented in accordance with the targets of the Horizon 2020 objectives regarding excellent research, stable working conditions and the implementation of the triple “i” dimension through:1) two international mobility options (a global outgoing phase of 18 months – artes global, or an inner-European outgoing phase of at least 12 months - artes EU);2) extensive guidance by an interdisciplinary and international team of 3 supervisors and within multidisciplinary Graduate Classes;3) support for a prompt transition into subsequent career stages thanks to the career development programme and a close cooperation with various intersectoral partners.artes EUmanities will guarantee a sustainable impact on the whole institutional structure of the ASGHC, transforming it into an excellent European graduate school with a strong international outreach and a distinctive interdisciplinary approach. It will offer Europe a leading model for innovative DPs and research tra
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Promoting Friulian within Multilingual Education: A cross-country, cross-stage, cross-level comparison of Friulian and Basque teachers’ language attitudes and motivation in search of best practices' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

This project focusses on the issue of teachers’ language attitudes, motivation and practices by targeting the promotion of the Friulian minority language in education in multilingual Friuli Venezia Giulia (FVG). Although figures for speakers vary between 35% and 49% of the total population of FVG, Friulian is classified as “definitely endangered”; however, despite legislative attempts, it has still not been fully integrated in school programmes. The picture emerging from a recent survey on speakers’ habits and opinions towards Friulian is not negative, but it does not explore the school situation, i.e. how Friulian is perceived by teachers, crucial actors as far as language promotion is concerned. Addressing the issues dealt with in the two European Parliament Resolutions on multilingualism and on endangered European languages, this mixed-methods research will allow a comparison of prospective and in-service teachers’ attitudes with respect to teaching (through) minority languages, by comparing FVG and the Basque Autonomous Community in Spain, a well-known context for the success of the revitalisation of the minority language within a multilingual educational system. The research also aims at identifying examples of best practices of multilingual education to disseminate in the Friulian-speaking area. Such comparison is original and innovative as it parallels two contexts with a minority language which harbour a desire to internationalise their educational systems: it will allow to better frame and understand the weaknesses of the FVG system and identify possible steps that should be taken to promote the Friulian language, tackle the challenges of globalisation, while boosting knowledge of foreign languages and multilingualism. This fellowship will enable the ER, who sp
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Transfer of multivirus-specific T-cells following transplantation' (TRACE), addressing dissemination and exploitation.

assistant: **Impact**

Allogeneic stem cell transplantation (HSCT) is a curative treatment for a variety of diseases. Viral infections such as Cytomegalovirus (CMV), Epstein-Barr-virus (EBV) and Adenovirus (AdV) are major unsolved problems for patients receiving allogeneic HSCT. Refractory viral infections post-HSCT are rare, life-threatening conditions due to the deficient T-cell response post-SCT and lacking effective treatment options. Protective T-cell immunity could be restored by means of a procedure known as adoptive T-cell transfer. Although cellular immunotherapy is considered a major recent breakthrough in medicine, none of the cellular treatment approaches has yet become a standard treatment. The reason for this limited translation into daily clinical practice is the lack of controlled, prospective clinical trials investigating efficacy of immunotherapy. The objective of TRACE is to bring adoptive T-cell transfer into clinical routine as a life-saving, curative and safe treatment for refractory viral infection post-HSCT. TRACE is a multi-national clinical trial to prove efficacy and safety of adoptive T-cell transfer in immune-compromized individuals. For the first time, this trial will show that a unique individualized immunotherapy could be included into evidence based clinical routine in rare diseases. Regulatory and structural hurdles will be overcome by standardized GMP-procedures. It will be a major milestone in the development of medicine and health economics to bring such a unique personalized treatment approach into a clinical efficacy trial. The consortium provide excellence in immunotherapy through partners from basic, clinical and industrial research and GMP facilities, with proven qualification and expertise in the field of HSCT, GMP manufacturing and adoptive T-cell t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Quantum Measurements with Bose-Einstein condensates strongly coupled to nanophotonic structures' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Most of the technologies at the heart of our information society, including the semiconductor and the laser, are based on the laws of quantum mechanics. Yet, there is still a lot to gain in harnessing quantum physics at the elementary level, for example to overcome the sensitivity limits in various kinds of measurements in the quantum regime. In this project, we plan to explore an emerging field of quantum technologies at the boundary between atomic physics and nanoscience, by studying the properties of Bose-Einstein condensates coupled to the evanescent field of nanophotonic structures. We will use this new light-matter interface to build a hybrid quantum gyroscope where the optical Sagnac effect in a photonic integrated circuit is enhanced by slow light in a Bose-Einstein condensate strongly coupled to it. The optical structures will be integrated on atom chips, for improved stability and scalability. Beyond the gyroscope itself, this work will create new prospects for combining the technological opportunities of nanophotonics with the very fruitful field of atomic physics, opening new avenues in quantum technologies, which are expected to become in the near future a key driver for the European competitiveness in information technology.