RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Intelligent Multi-modal Transfer Flow Management system' (2014-2020) under Horizon 2020.

assistant: **Objectives**

In sustainable transport systems, the role of multi-modal trips is increasingly important. Access, egress, and transferring within or between modes is an important source of trip disutility. The transfer experience needs to be substantially improved for multi-modal trips to be able to compete with car travel.  This proposal focusses on making transfers at multi-modal transfer hubs as efficient, reliable and safe for the traveller as possible within existing transfer hubs using advanced sensing and actuation technology, state-of-the-art control strategies and our knowledge of passenger behaviour. We valorise technical and scientific results of the ALLEGRO project and apply it to design and test a pedestrian traffic management system for multi-modal transfer hubs.  At the basis of the system is a state-of-the-art real-time monitoring system, that will collect and combine data from different types of sensors to estimate, predict and diagnose the flows inside the hub. The state-of-the-art sensors provide data with different semantic properties, ensuring that a comprehensive estimate of the current situation can be provided. One of the unique elements is the integration of sentiment information, stemming from social data analytics developed in ALLEGRO. Using a multi-faceted diagnoses system allows identification of problems in terms of traveller comfort, efficiency, and safety.  The models developed in ALLEGRO are used to provide short-term predictions based on real-time sensor data, which prevents myopic decision making based on the current situation in the transfer hub only. Off-line pilots have shown the feasibility of using predictive approaches to provide decision-makers with advice on which actions to take. We will further develop and validate these approaches by testi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Investigation and Control of Hydrogen flames Across the Scales' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

ICHAruS is a Doctoral Network aimed to train early-stage researchers, able to face current and future challenges in the field of innovative, edge-cutting technologies based on electro-magnetic assist to achieve full control of the hydrogen flames. ICHAruS has been built to provide doctoral training in a collaborative partnership between academic and industry partners who are major European gas turbine manufacturers. The aim of this partnership is thus to understand the physical processes that govern the interaction between hydrogen combustion and electro-magnetic fields at all flow scales to achieve such control and identify the key parameters that would allow for the design of an innovative, ultra-low NOx and flashback-proof combustion device. The behavior of hydrogen flames under plasma discharge and electromagnetic conditioning offer the opportunity to strongly accelerate the path towards zero-carbon energy and transport sectors. Three specific research objectives will be pursued:  1) Investigation and modelling of electromagnetic field effects on the species transport and chemical kinetics to unveil the effect of external electromagnetic fields on the reaction chemistry of hydrogen in both pure oxygen and air, and also determine any effects on the formation of pollutants. The effect of differential diffusion on the flame structure as opposed to electromagnetic drift will be also investigated. 2) Develop turbulence combustion models for low- and high-energy electromagnetic assisted combustion. The competing effects between electromagnetic drift and turbulence transport will be investigated and sub-grid scale closures for large-eddy simulations that consider the effect of electromagnetic fields and plasma will be developed. 3) Experimental and numerical investigation
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Engineering of new-generation protein secretion systems' (ProteinFactory) targeting Horizon 2020.

assistant: **Abstract**

The market for recombinant proteins, including biopharmaceuticals, industrial enzymes and membrane proteins, is estimated to be about 78 billion Euro and rising. A high proportion of the target proteins are produced in bacteria, where secretion out of the cytoplasm is a favoured strategy. However, current production platforms have severe limitations and cannot handle many secreted enzymes and membrane proteins. There is an overwhelming need for new production systems that can deliver these products in greater yields, with higher quality and at lower costs. The 'ProteinFactory' ETN will meet these challenges through the provision of a suite of super-secreting strains with unique capabilities. These strains will be engineered to bypass major production bottlenecks such as secretion stress, and will be capable of secreting an unprecedented range of target molecules. Equally important will be the training of a new generation of researchers, versed in Systems and Synthetic Biology approaches. The ProteinFactory project will involve extensive collaboration between 6 academic Institutes, who provide world-leading expertise in synthetic biology and protein secretion, and 5 non-academic partners who include some of the world's premier biotechnology companies. Training will be inter-sectoral from the outset, with every ESR undertaking extensive secondments within the non-academic partners in order to encourage an entrepreneurial mind-set. The project is furthermore explicitly multi-disciplinary in scope, with two of the five research work packages dominated by theoretical approaches. Based on a responsible innovation approach and with a clear focus on inter-sectoral collaboration, ProteinFactory will deliver a cohort of superbly-trained scientists, put the industrial and SME part
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Integrating Adaptive Learning in Maritime Simulator-Based Education and Training with Intelligent Learning System' (2021-2027), addressing dissemination and exploitation.

assistant: **Impact**

While all educational sectors have been affected by the COVID-19 pandemic, the vocational-oriented academic training components in higher education sectors have been more severely affected than others. For undergraduate and graduate students studying for a career at sea, the pandemic has led to suspension to their simulator training sessions, vocational learning opportunities and future careers. The simulator-based education and training domain, which forms the platform of skilled manpower supply for the maritime industry, faced unprecedented challenge to ensure the continuity of the educational activities and to cope with the constraints imposed by the pandemic. High-quality vocational education is the cornerstone of effective youth transitions into the labour market for the European society. The disruption of simulator-based training and tutoring sessions has led to concerns regarding whether the higher and vocational educational institutes can produce a sufficient and competent workforce who could adequately carry out on-board navigation functions safely and efficiently in the near future. By accounting for the needs, knowledge gaps and challenges faced by today’s maritime education and training sector, the i-MASTER project aims to integrate emerging technologies in vocational education and training to develop an innovative Intelligent Learning System (ILS) with maritime learning analytics and adaptive learning function to facilitate both remote and on-site maritime simulator-based education and training. The i-MASTER solution will significantly enhance the effectiveness and accessibility of simulator-based education in the European society and further improve safety, security and performance of maritime operations of the future.


**Keywords:** Vocational education
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how '2PS - Prevent & Protect Through Support' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

The European Commission’s latest strategy for fighting child sexual abuse highlights a harsh reality that, globally, we are ‘losing the battle’ against online child sexual abuse and exploitation (OCSEA). Various projects funded through the EU are working diligently to identify the source of CSAM on both the Clearnet and Darknet and are establishing stronger awareness of the needs and requirements of LEAs to fight the overloading volume of images, text, media files, etc. However, the IOCTA 2021 report also brings a chilling honesty that the prevalence of materials shows no sign of slowing or stabilising. The adage that prevention is better than the cure never seemed more fitting. The 2PS project condemns all forms of sexual abuse and exploitation – and there are no excuses that justify behaviours and actions that harm or victimise children. However, to reduce the number of abused children and those at risk of exploitation, we need to address various challenges. Several of those relate to people with a sexual interest in children and their needs to divert them from abusing. 2PS, which stands for Prevent & Protect Through Support is a highly innovative action offering a paradigm shift in the approach to tackling child sexual abuse and exploitation (CSAE) across Europe. The highly qualified and diverse consortium – together with leading global actors – are committed to laying the foundations for new coherent modus operandi that complement the reactive approaches currently favoured. This is achieved by addressing the support needs of people with a sexual interest in children and people who feel they might offend. We will share the best practices for guidance, therapy and treatment methods – combined with new training and awareness for frontline support workers and LEAs. We a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'SPECIFICALLY INTERACTING POLYMERS– From Selective Adhesion toward Specific Recognition' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

The ability to control interactions in synthetic polymers as precisely as in proteins will have a significant impact on polymer and material sciences. The present proposal explores broadly applicable routes toward synthetic polymers having the capability of specifically interacting with distinct targets such as small molecules, surfaces, or material interfaces.Novel design strategies for peptide-polymer conjugates will be established, which broadly exploit combinatorial methods for the selection of suitable peptide segments. Understanding the requirements for specific interactions will ultimately enable the synthesis of non-peptidic block copolymers that can mimic specific peptide interactions.The striking opportunities that arise from the newly established platform of “specifically interacting polymers” will be demonstrated in three case-based studies on: (1) Specific solubilizers & transporters, which specifically host, transport and actively liberate problematic high-potential drugs. (2) Specific surface recognizers, which enable material-specific adhesion to generate, with office laser printers, penta-functional paper surfaces or 3D-channels. (3) Specific compatibilizers, which allow tailoring of internal material interfaces to fine-tune sustainable composites via specific interface design.This project will encourage the synthesis of next-generation functional polymers that offer exciting new possibilities for specific materials sciences.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Multi monitoring medical chip for homecare applications (M3-C)' under Sixth Framework.

assistant: **Concept**

M3-C is a CRAFT project which aims to provide a group of SMEs from Germany, Sweden, Spain and Poland, whose business interests include medical equipment development and distribution, systems integration and healthcare information management systems, with access to advanced system-on-achip (SoC) technology to enable them to expand from their existing business positions into the emerging homecare and ambulant medical devices markets. The project will enable these SMEs to contribute effectively to the goals of eHealth. Three RTD performers will apply state-of-the-art techniques such as the application of multiplexed analogue components within sigma-delta modulators to the SoC design. Higher performance smallarea digital cells and multi-channel digital filters will help reduce the chip area and power dissipation. Auto-calibration concepts will overcome the effects of non-ideal behaviour of analogue parts. Built-in self test (BIST) schemes will be implemented in order to increase the reliability of medical devices. A digital signal processor (DSP) core will be integrated, making on-chip data compression and signal feature extraction possible. Compression algorithms will be defined to run on the DSP-based platform, which minimise the requirements for data storage/transmission. The proposed developments include implementation of BlueTooth TM Wireless Technology for wireless communication. It is envisaged that the results will permit multi-functional bio-signal processing devices (e.g. for EEG, ECG) to be developed which are 50% smaller and can be operated at approximately half of today's power consumption, providing the SMEs with opportunities for developing new generation wearable and possibly even implantable biosensors. The next two decades will see dramatic changes in the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Development & characterisation of a pre-vascularised tubular scaffold for tracheal regeneration that supports the formation of an iPSC-derived epithelium'.

assistant: **Innovation**

Tracheal damage is often life-threatening, and its incidence has increased due to invasive mechanical intubation of COVID-19 patients. Short defects undergo a surgical procedure (anastomosis), but this is not feasible for extensive defects. While bioengineered approaches for such defects have been investigated, there has been little translation into the clinic as implants weaken over time and fail to support the formation of neotracheal tissues. I aim to solve this problem by developing and characterising 3D printed tubular scaffolds for use as medical devices for tracheal restoration via a Global Fellowship involving Royal College of Surgeons in Ireland and Boston University, followed by a non-academic placement in CellInk. Scaffolds will be designed to mimic tracheal biomechanics and will be extensively characterised. Induced pluripotent stem cells (iPSCs) will be used to develop a pre-vascularised mature respiratory epithelium on disc scaffolds in combination with endothelial progenitors and human mesenchymal stem cells (hMSCs). The tri-culture will then be moved into the tubular design and the pre-vascularised mucosal substitute will be grown and assessed in vitro as an approach for ex vivo seeding of tracheal grafts prior to implantation. The ability of the tubular scaffold to support the growth of cartilage tissues will be assessed using a combination of bioprinting and differentiation of hMSCs. iTRACH will provide me with crucial training in advanced research skills (iPSCs, stem cell biology, biomaterials & 3D printing) and transferrable skills (Intellectual Property, Project Management, Entrepreneurship, Professional Enhancement and Science Communication). This fellowship will provide me with the required technical and complementary skills to enhance my employab
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'DOMESTIC HOT WATER SMART MANAGEMENT' (NESS-SW), addressing dissemination and exploitation.

assistant: **Impact**

Domestic Hot Water (DHW), defined as human water needs (such as personal hygiene, toilet flushing, laundry, cooking and cleaning) is the dominating use of water in buildings and occurs in both residential (households) and non-residential (commercial, public and industrial) facilities. The residential water use represents 72% of the total water use in buildings, and 28% for non-residential buildings.It is in this framework where METRICA6 finds its Business Opportunity within two different markets which account for i) around 81 million households with 3 or more inhabitants, and ii) more than 180.000 SME hotels in Europe.The project objective is to introduce into the global market an INNOVATIVE SMART MANAGEMENT SYSTEM for DOMESTIC HOT WATER CONSUMPTION that brings the hot-water to the point of consumption, maintaining the taps closed and without wasting a drop. The system aims to allow control, program and register the DHW consumption in households and other kind of facilities with similar consumption patterns like hotels, improving the first NESS-basic product available in market since the second half of 2015.The NESS-SW system will constitute an integrated solution to recirculate all the water in non-proper temperature using the elements of the conventional plumbing installation, warning the user when the hot water is ready. In addition, the DHW Management System will allow the user to remotely control water consumption parameters. The successful introduction into the market of NESS-SW will enable to reduce water loses in the domestic sector as one of the most immediate measures to decrease consumption by the individual user.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'MacroAutophagy and Necrotic Neurodegeneration in Ageing'.

assistant: **Concept**

Necrosis contributes critically in devastating human pathologies such as stroke, ischemia, and age-associated neurodegenerative disorders. Ageing increases susceptibility to neurodegeneration, in diverse species ranging from the lowly nematode Caenorhabditis elegans to humans. The mechanisms that govern necrotic neurodegeneration and its modulation by ageing are poorly understood. Autophagy has been implicated in necrosis and neurodegeneration, both with pro-survival and a pro-death roles. Autophagic flux declines with age, while induction of autophagy enhances longevity under conditions such as low insulin/IGF1 signalling and dietary restriction, which extend lifespan across diverse taxa. Our recent findings indicate that organelle-specific autophagy, including mitophagy, pexophagy and nucleophagy, is an important, evolutionarily conserved, determinant of longevity. We propose to dissect the molecular underpinnings of neuron vulnerability to necrosis during ageing, focusing on cargo-specific macroautophagy. To this end, we will implement a multifaceted approach that combines the power and versatility of C. elegans genetics with advanced, in vivo neuronal imaging and microfluidics technology. Our objectives are fourfold. First, we will monitor autophagic flux of organellar cargo, during neurodegeneration, under conditions that alter lifespan and identify mediators of organelle-specific autophagy in neurons. Second, we will conduct genome-wide screens for modifiers of age-inflicted neurodegeneration. Third, we will interrogate nematode models of human neurodegenerative disorders for organelle-specific autophagy and susceptibility to necrosis, upon manipulations that alter lifespan. Fourth, we will investigate the functional conservation of key mechanisms in mammalian mod