RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Reverberating abrasive single use piezo electric driven device' (RASPED) under Sixth Framework.

assistant: **Objectives**

Hip prosthesis implantation is one of the most common operations carried out in the EC today (approx. 700,000 across Europe per year). The technique for hip implantation requires the use of a surgical mallet impacted against a smooth tap or broach to open and expose the intramedullary canal in the top of the femur, this opening is the insertion site for the hip prosthesis. This impact based process causes high stress in the femoral component; infra-operative femoral fractures occur in approx. 17% of cases resulting in over 115,000 surgical and post-operative complications per year. We aim to develop a surgical rasp (high carbon steel surface with pressed and ground teeth) and piezo ceramic drive system to actively remove the trabecular bone, spongiform and bone marrow from the intramedullary canal (femur).The more effective cutting and removal process of our rasp and drive mechanism will negate the need for impact based surgical methods and reduce the occurrence of femoral fractures. This new surgical tooling will simplify hip surgery, reduce the rate of femoral fractures. It will improve the competitiveness and productivity of the communities of small firms providing surgical equipment and the community ofsmall, medium and large organisations, the end users and distribution population. After the project, the base technology will find applications in other surgical prosthesis implantation, dental and mining industry, consequently these developments will benefit a wider community of small enterprises servicing these sectors. Our aim is to provide a surgical tool to reduce the risk of femural fractures during prosthetic hip implantation, based on the RASPED tooling being used in 10% of all European hip implantations by 2012 and that we estimate that we will reduce the fem
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Future energy technologies for enlarged European Union' goes beyond current state-of-the-art under Sixth Framework.

assistant: **Innovation**

The overall objective of the project is to facilitate the participation of the Associated Candidate Countries (ACC) in Priority 6.1 of the 6th Framework Programme and a good start in the 7th Framework Programme. This will be done by: 1. conducting a detai led mapping exercise of the research groups in the ACC and Member States (MS) working on future energy technologies and creation of detailed databases of researchers and research organisations in ACC which contain information that would facilitat e partner searching for the creation of consortia. 2. establishing international experts groups, 3. building awareness of the opportunities presented by the Framework Programme and facilitating interactions between the scientific communities in the AC C and MS by organizing series of regional info-days joined with brokerage events 4. promotion and other activities supporting the Framework Programme 5. elaborating strategies for integration of research and technology development groups from enlarged EU  in the area of new energy technologies.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Imaging of multiple mRNA targets using SERS nanoparticle labels and in situ hybridization in human cancer tissue sections' in the context of a Horizon 2020 call.

assistant: **Objectives**

Early cancer diagnosis greatly increases the chances for successful treatment and personalised therapy. RNA molecules have emerged as new candidate biomarkers for detecting a wide variety of cancers, due to their critical role in cell growth and development. In situ hybridization techniques for mRNA detection provide detailed spatial and temporal information on RNA expression with single-molecule sensitivity, however the traditional techniques that utilise fluorescence probes and quantum dots lack of high multiplexing capabilities. RISH seeks to develop a methodology that allows sensitive multiplex detection, quantification and distribution of cellular mRNA biomarkers utilising surface-enhanced Raman spectroscopy (SERS) nanoparticle (NP) labels. SERS NP-labels consist of metal nanoparticles modified with a self-assembled monolayer of Raman reporters and are sensitive and robust labels that offer great multiplexing capacity. Molecular beacon hybridization probes specific to mRNA targets will be conjugated to SERS NP-labels to allow optical detection utilising Raman microscopy in human cancer tissue sections. The mRNA expression levels will be correlated with those from fluorescence in situ hybridization and the respective protein expression levels after immunohistochemistry. The research proposal is highly multidisciplinary and includes aspects of spectroscopy, optics, biochemistry, nanotechnology and pathology. The research fellow plans to work closely with experts from both the hospital and the industry to apply this methodology in the diagnosis of initially breast cancer and of different types of cancer at a later stage.


**Keywords:** Surface-Enhanced Raman Spectroscopy, Raman, Tissue, RNA, mRNA, Nanoparticles, Cancer, Imaging, In situ hybridization,  Fluorescence,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Dynamic Effects in Thin Liquid Films' (DETLIF) targeting Seventh Framework.

assistant: **Abstract**

The proposal “Dynamic effects in thin liquid films” is devoted to studying the DLVO surface forces in dynamic conditions. During the film drainage a number of complementary phenomena on the film surfaces occur, which affect the total interaction between them. For example, the surfactant adsorption and the distribution of the surface charges upon the film surfaces are affected by the process of film thinning. Therefore the electrostatic and the van der Waals forces are not homogeneously distributed upon the film surfaces  and the total surface charge density varies with the film thickness. The pressure tensor in the draining liquid films is asymmetrical. These effects are generally avoided in the current hydrodynamic theory of thin liquid films. The utilization of such theory in studying non-DLVO surface forces can create a certain misleading and wrong interpretation of the experimental results.    The present proposal  contains  a concise theory (set of equations) accounting for the dynamic effects on the DLVO forces in thin liquid films. The set of equations will be solved numerically. The theory will validated by experiment.  The outcome of this proposal is “purified” from the basic approximations regarding the surface forces hydrodynamic theory of thin liquid films. This theory can be trusted for studying non-DLVO forces in dynamic liquid films.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Direct determinations of polar stratospheric cloud composition', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

There are three primary objectives with this instrument development project: - to improve the design of an existing Lyman-` hygrometer to give the instrument increased sensitivity and a lower detection limit for water vapor such that it can be used in conjunction with the CVI to measure the condensed water content of PSCs and upper-tropospheric cirrus clouds. - to adapt a laser-diode spectrometer system used to measure HNO3 for use in stratospheric conditions and incorporate it into the CVI sampling system. This instrument would then be used to measure the nitric acid content of polar stratospheric cloud elements. - to prepare an instrument payload which can be used to directly and in real time measure the composition of the condensed phase in PSCs with quantitative determination of H2O and HNO3 contents. Together with simultaneous measurements of the cloud element number concentration (COPAS project) the goal of the experiment is a comprehensive in situ analysis of the condensed phase in polar stratospheric clouds.The project involves developing two new instruments for measuring H2O and HNO3, incorporating the  instruments into a common payload for deployment on the M-55 Geophysica aircraft, and interfacing the  combined instrument payload with the Counterflow Virtual Impactor (CVI) probe developed as part of the  COPAS project.  a) H2O Instrument  The new H2O instrument design will be based on current Lymanhygrometers presently in use on various  aircraft payloads. A new instrument based upon these hygrometers which will be optimised for use in the  stratosphere will be constructed. The largest challenge will be to increase the sensitivity of the new hygrometer  by a factor of 100 relative to the instruments now in use. There are several ways to achieve this decrease
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'International Network on Ionic Liquid Deep Eutectic Solvent Based Metal Organic Frameworks Mixed Matrix Membranes.'.

assistant: **Objectives**

The main objective of INDESMOF Marie Curie RISE action is to establish a new and lasting research consortium to improve and exchange interdisciplinary and intersectoral knowledge on the design, synthesis, and characterization of advanced composite adsorbents for environmental remediation of heavy metal polluted water sources, able to provide high capacity and high selectivity filters for the industry. The main research core of INDESMOF is based on the nano-encapsulation of Deep Eutectic Solvents (DES) within the ordered porous structures of Metal Organic Frameworks (MOF), in order to obtain a highly porous MOF material, combined with the metal chelation and solvation specificity of DES. Incorporation of high-capacity high-selectivity adsorbent materials within polymeric support is a crucial challenge faces in INDESMOF towards the real application of the MOF@DES materials in water filtering systems, indispensable for mining and industrial water environmental remediation technologies. Development and improvement of advanced filtering technologies requires the joint effort of a multidisciplinary researcher collective, involving the expertise of participants on different disciplines including physics, chemistry, environmental chemistry, materials and polymer science and engineering. Background knowledge and knowhow of INDEMOF´s partners combine the complementarities and synergies needed to undertake an integrative and concerted effort through innovation and breakthrough actions towards the fabrication of advanced and specific filters for polluted water remediation. Results will be widely disseminated through publications, workshops, post-graduate courses to train new researchers, a dedicated webpage, and visits to companies working in the area. In that way, we will perform
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Microbial Degradation of Jellyfish-Derived Substrates'.

assistant: **Concept**

The complex pool of dissolved organic matter (DOM) in the oceans is almost exclusively accessible to diverse members of microbial community carrying out different types of metabolism thereby, affecting biogeochemical state of the ocean. To predict the response of the marine ecosystem to natural and anthropogenic perturbations, a mechanistic understanding on the relation between the organic matter (OM) field and the metabolic network operated by the microbial community needs to be refined. One largely overlooked, but significant source of DOM are jellyfish. Regardless the debate over the accuracy of their reported global increase and on the true cause of the observed jellyfish fluctuations, the increase in their population size can have serious ecological and socio-economic consequences. As jellyfish blooms decay, sinking carcasses represent large quantities of detrital OM (jelly-OM), rich in proteins and hence, a high quality substrate for the ambient bacterial community. However, the exact processes and mechanisms of bacterial jelly-OM degradation remain unknown. In the MIDAS project, an integrated interdisciplinary approach will be applied to characterize the composition of jelly-OM at the molecular level and the metabolic network operated by jelly-OM degrading bacterial communities using state-of-the-art analytical tools (ultra-high resolution mass spectrometry) and cutting edge –omics techniques combining emerging fields of marine metaproteomics and exoproteomics. This knowledge will enable us understanding the implications of jellyfish blooms on biogeochemical cycles in coastal seas.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Self installing platform' will create measurable scientific, societal and economic impact aligned with Fifth Framework.

assistant: **Impact**

To demonstrate to the oil and gas industry the viability of the Self Installing Platform for marginal oil and gas fields in order to give the industry the confidence to use the concept in the development of small fields which were thus far not economically exploitable.Its key features are:- The advantages of using suction pile technology for the platform foundation avoiding heavy lift crane barges or heavy duty piling equipment- The vertical float out method for the complete platform including topsides of up to 500 tons- The potential to remove the platform and to re-use it for another application- To provide a low cost alternative for the development of small fields- To establish the capability of the consortium and the EU to bring this SIP to the market
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'GLOBAL excursion - Extended Curriculum for Science Infrastructure Online' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

GLOBAL excursion will introduce e infrastructures to educators and pupils. It provides scientists, policy makers, pupils and their teachers a package of activities, materials and tools for enabling the integration of e infrastructures into school curricula. Main access point is the GLOBAL Virtual Science Hub – ViSH". It contains a selection of e Infrastructures, and a social network where scientists, teachers and pupils will be able to exchange and establish collaborations, and a virtual excursion room, where pupils will be able to experience real e-science applications in areas of high relevance for the future, such as nano- and biotechnologies.The technological basis of the Virtual Science Hub is the VCC, a communication platform developed in the GLOBAL project, which has already proven to successfully link distant researchers and to integrate remote regions.To allow for closer links between stakeholder communities, the hub will include a pedagogical framework that tailors science content to the needs of schools preconditions. With this aim, teachers and scientists will be involved in a user-centred design process and collaboratively elaborate generic tools and methods, offering joyful formats attractive to young people. With the ViSH portal as a hub, virtual excursions are possible through existing e-infrastructures and together with pedagogical concepts, a more efficient use of e infrastructures will be ensured. Teachers will have access to guided and compact materials, easy to implement and adapt in their teaching activities.<br/>Together with end-users, GLOBAL excursion will develop a common understanding, teaching use cases, as well as pedagogical and technical artefacts. The aim of this project proposal is to provide young citizens and their educators (teachers,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Simultaneous Elemental and Molecular Imaging of Biological Targets – A New Paradigm for the Study of Disease and its Treatment'.

assistant: **Objectives**

This project proposes the development of a technology capable of delivering, high speed, simultaneous elemental and molecular maps of biological targets. Specifically these targets will include plaques associated with age-related macular degeneration (AMD), tumours treated with Pt-based chemotherapy drugs, and cell populations derived from the FP7 project, the ONE Study.  The dual-mode imaging system will enable the analysis of metallo-proteins and their binding sites, or where there is no native metal tag or its abundance is too small to detect, anti-body or specific reactive chemistry metal or nano-particle tags will be added to the target molecules. For the ONE Study, one of the key project aims is to develop cell labelling strategies that will enable therapeutically administered cells to be tracked at low abundance in the host cell populations without toxic impact on either the therapeutic cells or host organism.The technology will be based on employing a common pulsed laser platform for laser ablation, desorption, or matrix assisted sampling of the target material simultaneously coupled with inductively-coupled plasma elemental mass spectrometry (ICP-MS) and ion trap organic mass spectrometry. In the case of the molecular mass spectrometry, electro-spray or matrix assisted charging will be used. The sampling will employ a technology developed in the host laboratory that enables targets to be sampled at atmospheric pressure whilst excluding atmosphere from the sampling point. The technology will be optimised for high speed and high efficiency to enable rapid mapping of targets at very high sensitivity. This will require development of a new high efficiency torch design for ICP-MS and the novel use of micro-jet pumps to deliver samples to the mass spectrometers.The p
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'reduce - recycle - reuse eMobility - retrofitting-kits for busses' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

The overall objective of the envisaged project is to establish a production system for refurbishing and retrofitting the bodies of diesel-driven-busses after their service life. These bodies are usually still in a very good condition and have a high potential for being refurbished and retrofitted with electric powered drive systems. In Germany the public transport sector is about 39.600 busses  strong (2013). Only 46,6% of these buses have EURO-IV and higher, 20,4% EURI-III, 23,5% EURO-II and 9,5% are much older. European wide (EU27) there are about 8.200.000 busses and coaches ! Like in Germany (39.600 of 79.200) around 50% of this are busses in public transport – around 400.000 busses. This shows the high potential of this market in whole Europe like this map  is also showing. Retrofitting is not only a sustainable way to use resources , but it is also economic feasible for the customer, because the body and many of the components are reused and have a remaining value about 100 – 200 T€!Furthermore, the ecologic impact plays a more and more important role. First cities decided to close their inner cities up to 2020 for diesel-vehicles (for example Paris ) or for vehicles with CO2-emissions (for example London) or Copenhagen as carbonneutral city up to 2025  . We can be sure, that other regions and cities will follow. E-mobility is the key to success and needs further funding for development.The objective of this project is to demonstrate, that rebuilding  busses with electric powered drive systems will have a significant market in Europe and a large and sustainable benefit for the public transport sector:•economic wise, because the operational costs are about 50% cheaper than diesel-driven busses (assembly, operation, maintenance)•innovation wise, because these vehicl