RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Advanced structure prediction methods' demonstrating excellence, impact and implementation quality for a Sixth Framework call.

assistant: **Abstract**

Cancer cells are induced to develop by pathological disfunction of signalling pathways. These are mediated by interactions between proteins in signalling cascades. As these processes are potentially specific for cancer cells, they offer the unprecedented opportunity to selectively intervene against tumour cells, without causing harm to normal cells. As signalling pathways are mediated by interactions between diverse signalling proteins, a straightforward possibility is to selectively inhibit specific signals is to block specific protein-protein interactions.However, the contact areas between these proteins are often large, and most conventional drugs are too small to modulate these interactions effectively. Diverse chemical-, peptide- or whole-protein-based structures can be utilized as highly specific drugs. These are expected to modulate specific signalling pathways effectively, and to have much milder side effects on the patient. This approach is critically dependent on knowing the structures of the targeted proteins. However, in many cases the structures of the proteins concerned defy experimental determination, so we are critically dependent on prediction methods. These are not yet sufficiently accurate, so we are proposing to make a serious attempt a t improving them.Three experienced researchers, with complementary expertise at protein structure prediction methods; bioinformatics, structure analysis and experimental validation will be employed. Interaction with wet-lab researchers and previous experience in multidisciplinary environments will critically help the exchange of knowledge, results and experimental approaches. Important results in key areas of both basic science and application to cancer therapy are expected from the implementation of these strategies.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Protected starter cultures for the dairy industry' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Milk and its fermentation derivatives, yogurt and cheese, are globally consumed at rates of >750 million tonnes annually, and are responsible for ~10% of the protein consumption worldwide. In the process of yogurt and cheese production, starter cultures of lactic acid bacteria (LAB) are added to milk, leading to fermentative production of the end product. Optimal growth of the lactic acid bacteria within the milk is critical for high-quality fermentation in the manufacturing of such dairy products.During fermentation, growth of starter culture bacteria is frequently impaired by viruses (phages) that infect these bacteria. Phage infection of lactic acid bacteria fermentative cultures is the main cause for incomplete or delayed fermentation processes in the dairy industry, and it is estimated that 10% of dairy fermentation processes fail due to culture infection by phage. This puts an extensive financial burden on the yogurt and cheese industries, a market estimated at >$80B annually. There is therefore a strong need for tools that would protect lactic acid bacteria from phage infection during the fermentation process.In our ERC-funded project we discovered novel defense systems that confer strong resistance against multiple types of phages. We showed that our systems do not impair normal growth of bacteria, and provide efficient phage-resistance features, conferring protection against a broad range of phages. Within the current PoC project we will harness our discoveries to develop non-GMO prototype lactic acid bacteria that are strongly protected against phage infection. This prototype is expected to demonstrate highly resilient, enhanced starter culture bacteria that will have superior durability and resistance over currently available starter culture bacteria used in
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Carbon Reduction by Auxiliary Firing TEchniques for glass Melter' (CRAFTEM).

assistant: **Innovation**

Each year, the EU’s Primary glass melters producing container and flat glass consume some 150 PJ of energy and emit some 10 Gigatonnes of fuel related CO2. Most of the EU’s large glass melting furnaces already employ reversing regenerators to achieve a thermal efficiency of 50% or more, a very good figure for a process operating at about 1600˚C. The industry is facing conflicting challenges to reduce its carbon emissions while respecting ever tighter limits on nitrogen oxide emissions since increasing heat recovery from the exhaust gases through the use of more regeneration would result in an increase in NOx emissions. Responding to this challenge, three of the partners in the present proposal have developed and patented a new combustion strategy for glass melters (Auxiliary Firing). Auxiliary Firing has been shown on a glass furnace simulator to offer up to 5% direct energy savings. It also reduces NOx emissions to meet the 2009 EU limits offering further indirect energy savings by avoiding the energy currently consumed by some exhaust gas NOx clean-up processes (a further 5 to 10% of furnace fuel in some NOx reduction processes).The CRAFTEM proposal brings together the Auxiliary Firing developers and two major Glass Makers with the objective of demonstrating the new combustion process on two full scale glass melters. The demonstration furnaces will represent the two major firing configurations (cross-fired and end-fired) currently used on the majority of the EU’s glass melters. The aim of the demonstrations will be to show that Auxiliary Firing will yield the expected Carbon Savings while maintaining glass output and quality, and reducing NOx emissions to the 2009 EU limits. A successful demonstration will allow immediate replication of the new firing technique within
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Climate change impacts in a karst landscape of the Austrian Alps: effects on the soil resources', explaining its relevance to EU policy priorities under Sixth Framework.

assistant: **Impact**

The impacts of climatic changes can significantly alter a soil's inherent quality. Soil organic matter deserves special attention in this context because of its key role in many important soil processes, its rapid response to environmental changes, and its feedbacks to the atmospheric climate system.The overall objective of the proposed research is to enhance the understanding of climate change impacts on the soil resources of Alpine ecosystems, with particular emphasis on soil organic matter dynamics.The project will capitalize on the researcher's extensive experience in studying soil development along climatic gradients in the Andes. The study area of the proposed project is located on the Hochschwabkarst massif, from where drinking water is supplied to Austria's biggest cities, Vienna and Graz.Four methodological approaches will be combined to investigate climate effects on soil processes:- the empirical study of soils along climatic gradients (i.e. altitudinal climosequences);- manipulation experiments (i.e. translocation of soil cores to climatically different areas);- in-situ decomposition experiments in different elevation zones; and- simulation modelling.Proposed analytical methods include isotope dilution techniques and Fourier-transform infrared spectroscopy. With the experimental data collected in this project, existing carbon and nitrogen cycling models will be adapted and validated for the studied Alpine environment.The validated models will be used to assess the impacts of projected future climate change on the soil resources and associated environmental consequences.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Development of single and multi-analyte affinity sensors for rapid detection of androgen residues in live and post-mortem animals' demonstrating excellence, impact and implementation quality for a Fifth Framework call.

assistant: **Abstract**

This is an ambitious project that aims to develop new technologies in the field of biosensors. Specifically it will develop electrochemical affinity biosensors for inexpensive detection of residues of anabolic ally active residues in meat producing animals and in carcasses following slaughter . This is an innovative approach to developing sensitive, effective, fast and easy to use biosensors. The proposed sensors would allow widespread screening of animals and animal products before entry into the human food chain thus facilitating the implementation of EU directives on consumer protection.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Cost-effective PROton Exchange MEmbrane WaTer Electrolyser for Efficient and Sustainable Power-to-H2 Technology' to be submitted under Horizon 2020.

assistant: **Abstract**

The need for de-carbonization of our society is a pressing issue raising the attention at social and political levels. The production of high value chemicals and fuels such as methanol requires hydrogen derived at the moment from hydrocarbons and resulting in large emissions of CO2. Green Hydrogen produced by water electrolysis coupled to renewable sources could be the ultimate solution to this problem. Proton exchange membrane water electrolysis (PEMWE) is the most suitable technology for this process due to its compactness and flexibility. However, the dependence on precious metal catalysts and expensive components manufactured in titanium poses a serious threat for the scale up and market penetration of this technology. PROMET-H2 project aims to develop a pressurized PEMWE with the lowest capital cost ever achieved (500-750 €/kW) without compromising performance and durability. The stack, based on hydraulic compression technology, will contain improved membranes and electrodes with reduced or even free of precious metal contents and with coated stainless steel bipolar plates (BPP) and porous transport layers (PTL). The materials and components that will make this possible have already been demonstrated in laboratory and in PROMET-H2 these innovations will be implemented in a 25 kW PEMWE system. Such electrolyser will be coupled with a methanol production pilot plant from CO2. Materials recycling strategies will be developed and a deep LCA and cost evaluation will be realised to ensure that the new PEMWE can be scaled-up to meet the demands of large methanol industrial plants. A well-balanced consortium of 12 industry and academic partners will address these challenges in three years with the aim of achieving renewable methanol production. At the end of the project, t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'high-performance BIOPLAStic PROducts for new markets and applications' (BIOPLAS-PRO) targeting Horizon 2020.

assistant: **Abstract**

Environmental awareness, limited oil reserves and EU legislations are driving the need for eco-friendly alternatives to synthetic plastics. In this context, we present BIOPLAS-PRO, project aiming at developing and commercializing high-performance and cost-effective bioplastic products for the civil and advanced composite industry that contain more than 95% of starch-based biopolymers, are 100% eco-friendly, recyclable and O-degradable. Envisioned products include BIO-MAT and BIO-DRAIN, 3D structured mats for soil stabilization, erosion control and water drainage control, and BIO-CORE, a 2D/3D structured spacer and resin flow media used in composite products. Our products are produced by our unique isotropic extrusion-moulding process ensuring the best biopolymer processing conditions and highest quality products. We are the first company in the world to have successfully adapted this extrusion-moulding process to bioplastics. The Phase I feasibility study is required to set-up detailed product and production scale-up requirements and ensure the overall commercial viability of the project. The end users of our products are construction companies and enterprises manufacturing composite products. Their needs are high quality products and low environmental impacts. Our products provide similar or better performance to existing synthetic and/or natural solutions, are made 100% from renewable resources and have controlled biodegradability (100% degradation in 1-5 years). Within the first 5 years, we estimate to sell 13 kton of products, which will generate €30 million of accumulated revenues while reducing plastic waste by 10 kton and CO2 emission by 32 kton. This is perfectly in-line with EU strategies on reducing the use of harmful materials and improving waste management.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Multiscale reinforcement of semi-crystalline thermoplastic sheets and honeycombs' (M-RECT).

assistant: **Innovation**

The M-RECT project aims to create multiscale-reinforced semi-crystalline thermoplastics (PEEK and PPS), which will outperform all reinforced polymers in terms of strength, stiffness, creep and mainly damping by upscaling and further developing state of the art production methods, within cost-efficient manufacturing routes. The envisaged multiscale reinforcement will comprise of dispersed straightened and aligned to polymer molecules multi-walled carbon nanotubes (CNTs) and also fully impregnated, long carbon fibres (CF). In order to achieve this objective a number of novel technological achievements including CNT functionalization techniques, fluid-assisted CNT alignment, microwave and induction heating of composites, out of autoclave manufacturing including bagging techniques, DIRIS sandwich panel production, fluoropolymer radiation-absorbing coatings and polymer optical fibre technology will be further developed and used. The CNT or multi-scale reinforced PEEK or PPS sheets and the resulting sandwich panels will be used as raw material for manufacturing laminated complex prototypes covering a wide range of industrial applications such as automotive, railroad, aeronautical, space, civil engineering and biomedical. Optimized design of these structures will be based on suitably developed numerical modelling and optimization tools within the proposed project and which will be validated through extensive testing at nano, meso and macro-scale. The anticipated impacts of the development of the envisaged top-performance lightweight thermoplastic composites and their manufacturing routes will extend to an international level by decreasing energy and fuel consumption, decreasing waste production and improving recyclability, creating profitable spin-off activities, promoting saf
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Activist Techtopias: Crafting Alternate Infrastructures of Resistance in Asia' to be submitted under Horizon Europe.

assistant: **Abstract**

AlterTech is an ethnographic study of how democracy and human rights activists in Asia alter existing infrastructures of resistance - that is, the organising structures and organisational resources needed for social movements - in the face of digital repression. It studies how activists experiment with new practices and different uses of technologies that are less vulnerable to repression, envisioning these practices as technological craftsmanship. AlterTech traces how activists recombine digital, analogue, and material technologies to craft alternate, high- and low-tech infrastructures that enable activism under the radar of the state. The convergence of political and technological activism in these practices, AlterTech posits, engenders a novel kind of technopolitics and utopian imaginaries, or techtopias.Using the lens of infrastructure, AlterTech studies how this technopolitics takes shape across activist networks in different settings and at multiple scales. Through multi-modal, multi-sited, and multi-scalar ethnographic research among activists in Indonesia, India, and Thailand, exiles from Hong Kong and mainland China in Europe, and transnational NGOs that distribute knowledge and resources, it asks how local positionalities, transnational communities, and hemispheric politics matter to infrastructures of resistance.AlterTech innovates theoretically through an original framework that highlights the interplay of infrastructure, praxis, and utopianism, introducing original concepts such as crafting and decolonial infrastructural intervention. It breaks new ground methodologically through its co-creative participatory approach, in which researchers simulate the craftsmanship they study, developing inventive modes of knowledge production and dissemination. Thereby, i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Micro Gradient Polyacrylamide Gels for High Throughput Electrophoresis Analysis' (MICROGRADIENTPAGE) targeting Seventh Framework.

assistant: **Abstract**

Polyacrylamide gel electrophoresis (PAGE) is the most widespread tool to separate and detect macromolecules based on their molecular weight. New generation PAGE assays miniaturize the technique to obtain high throughput performance and reduce sample volume, reagents and cost. Here, we present a novel technology that will improve the range, the resolution and the accuracy that these new generation PAGE assays can resolve. On traditional PAGE assays, polyacrylamide gels with an acrylamide gradient are used to significantly improve the separation of macromolecules. However, on new generation PAGE assays the technology to fabricate those gradients at the millimetre scale with micron resolution is missing. The technology presented in this project, developed as a part of the ERC project GenesForceMotion, allows the fabrication of millimetre sized polyacrylamide gels with a well-defined and precise acrylamide microgradient. Moreover, the acrylamide density profile can be precisely controlled along the gel to improve the separation of macromolecules with similar molecular weights. This technology generates a market opportunity to improve the performance of the gel electrophoresis technique widely extended in worldwide life science laboratories. The expected outcome of the project is to test the benefits of our microgradient gel technology to improve the new generation miniaturized PAGE assays and make this technology available to the market
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'LOW ENERGY DRYING IN LEATHER INDUSTRY'.

assistant: **Concept**

Alternative drying of leather. Fratelli Carlessi"-type drying using a hot-air circulation system with steam of 150°C, 290KW, 500kg/Hr has been employed so far. The project is aimed at achieving equal or better quality of drying at a lower temperature using less energy. According to the orderer Wertleder, the highest quality is realized when drying is done in the range of life temperature (30-40°C). The use of energy is to be optimized by heat recovery.Output : 216 hides, 3.5kg water per hide in 6 hours.The leather drying plant is still under construction. Results cannot be given until the start of the test stage.The alternative solution comprises : - Putting the hot air circulation system and the heat exchangers with the medium steam out of operation. - Using a recirculating ventilation system with 15000 m³/hr. An external duct system ensures a turbulent flow through the gaps between the hides stretched over frames. Conditioning of the air is done in a compact air conditioner with the designation HÖLTA 503 which is arranged on the face of the dryer.- Conditioning units : reverse air filter EU 4, countercurrent plate heat exchanger, evaporator, drop collector, condensate trough, radial fan, preheater in the plate heat exchanger, postheater in the condenser and electric start heater. The compact air conditioner has a complete integrated refrigerating plant. Fan and compressor are fixed in a vibration-reduced manner. The condenser output of the refrigerating plant has to be 1.3 times the evaporator output. Therefore, an additional water-cooled plate exchanger is integrated into the compact air conditioner as a second condensation stage. The cooling-water circuit is externally recooled via a water-air cooler. A valve reversing gear is used to heat the hall with the heat rel