RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Determining the role of gamete small RNAs in propagating the trans-generational epigenetic silencing of transposable elements' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

A great portion of organism genomes are composed of “junk” DNA that their cells must stop from transcribing. This “junk” DNA is composed of transposable elements (TEs), which will generate mutations if allowed to express. However, each cell does not need to determine de novo what regions of the genome are TEs, rather this information is passed down from a progenitor cell in a process termed epigenetic inheritance. In both plants and animals, epigenetic inheritance occurs across mitotic cell divisions and, at least in plants, it also occurs across meiotic divisions and fertilization. Plant gametophytes and embryo are the battleground for the evolutionary arms race between TE activity and host-cell suppression of TEs. The protection of the germ cells and the very young embryo of the progeny are key steps of genome integrity that require trans-generational epigenetic suppression of TEs. The conceptual base of this project is that TE derived siRNAs accumulating in the pollen sperm cells (SCs) are part of a trans-generational genome safeguard mechanism that protects TE expression and transposition in the SCs and after fertilization in the embryo. This project will specifically investigate:Aim 1)The movement of pollen TE easiRNAs to the SCs, embryo and the endosperm.Aim 2)The role of TE easiRNAs in initiation of a siRNA amplification step in the embryo.Aim 3)The role of TE easiRNAs in the protection of the embryo’s genome from the transposition of female active TEs in the endosperm or/and the embryo.Aim 4)The role of TE SC siRNAs in imprinted embryo gene regulation.In order to achieve these aims, this project will make use of several molecular and cellular biology techniques. This will enhance the knowledge of the transgenerational epigenetic regulation of plant genomes, and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Magnesium and Aluminium Gas Injection Technology for High Pressure Die Casting' in the context of a Horizon 2020 call.

assistant: **Objectives**

TiK – Technologie in Kunststoff GmbH (TiK) was founded in 2004. The company is Europe-wide and especially in the automotive sector known as specialist for plastic injection moulding and the use of gas injection technology. In recent years, the company developed to one of the most innovative companies in product and process development for plastic components.The European automotive industry is faced with wide-ranging challenges in the common years. Especially electric mobility, lightweight design and intelligent use of materials is essential for current and future car development. In modern cars, many components are already produced in die casting, which is the most promising technology regarding cost-effective large-scale production. To extend the application possibilities of this technology, TiK developed a new and disrupting process, which enables the use of gas injection in aluminium or magnesium high pressure die casting and the production of components with hollow structures. Through this, significant cost savings can be achieved by the elimination of upstream and downstream manufacturing processes and weight can be reduced drastically by using lighter materials, but also new constructional possibilities for complex, hollow and thin-walled components with a load-adjusted design. By MAGIT, fluid-transporting components can be realized. These can be used for cooling of power electronics or temperature controlling of vehicle batteries.The new technology primarily addresses the European die casting industry for non-ferrous metals, which is a continuously growing market with an expect CAGR of 3.8% in the common years. Besides the gas injection system, which will be direct sold by TiK, further system- and customer-specific services will be offered by the company. By the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'New technologies and strategies for fuel cells and hydrogen technologies in the phase of recycling and dismantling' (HYTECHCYCLING).

assistant: **Innovation**

High deployment of fuel cells and hydrogen technologies is expected in the near term in the EU to decarbonize energy and transport sectors. The idea is to generate vast amounts of green hydrogen from the expected surplus of renewable energy sources (implemented policies are going towards 65% of electricity from renewable energy sources by 2050) to be used in transport (moving fuel cell electric vehicles), energy (feeding stationary fuel cells for cogeneration, injecting hydrogen into the gas grid) and industries (hydrogen generation for chemical industries).However, the expected commercial FCH technologies (mainly PEM and alkaline electrolysers as well as PEM and Solid Oxide fuel cells) are not prepared for full deployment in what regards to recycling and dismantling stage. The main goal of proposal is to deliver reference documentation and studies about existing and new recycling and dismantling technologies and strategies applied to Fuel Cells and Hydrogen (FCH) technologies, paving the way for future demonstration actions and advances in legislation. To achieve this goal, the following key steps will be followed considering the involvement and validation of relevant FCH value chain actors and the HYTECHCYCLING Advisory Board of manufacturers:1. Pre-study and techno-economic, environmental, RCS assessment related to dismantling & recycling of FCH technologies to detect future needs and challenges 2. Development of new technologies and strategies applied to FCH technologies in the phase of recycling & dismantling and LCA analysis considering critical, expensive and scarce materials inventory3. Proposal of new business model, implementation roadmap and development of reference recommendations and guidelines to focus the sector and pave the way for future demonstrations
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'The NanoLiter Reactor sequencing -- Quick and cost-effective method to develop microbial strains' (FGen) under Horizon 2020.

assistant: **Objectives**

Demand in bioproducts is increasing to answer the food needs required to feed the growing population. The current manufacturing of bioproducts- vitamins, amino acids, industrial enzymes- is heavily relying on the use of fossil fuels, whereas bio-based production can save water, energy all decreasing waste and costs. The use of efficient microbial strains allows bioproduct manufacturers to do so. The optimization process of the microbial strain is going under several cycles during which culture conditions are modified, and strains genetically modified, making the development long and costly. In addition, the scale-up is often complicated. FGen has developed a nano-reactor mimicking large bioreactor conditions allowing a high throughput screening of microbial strains, easing the scale-up and speeding the screening of the family strain respectively, all decreasing time and development costs. This nano-reactor having shown promising results, FGen aims to compile it with an innovative method to genetically modified the strains. The combination of these two methods will grant large chemical companies and biotech to save up to 3 years and around €45 M for the development of an efficient strain that will be used in the manufacturing of bioproducts. The estimated segment market for FGen is of €20 bn. With a time to market estimated at 3 years, FGen aims to act as service provider with external companies to generate revenues and to work on the development of its own strains to license or sold them. FGen estimates to generate a positive EBITDA of €5 M at 7 years (2025), and to grow-up to more than 100 employees.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'SI2-335701- SUSTAINABLE ROAD SURFACES FOR TRAFFIC NOISE CONTROL' (SILVIA) targeting Fifth Framework.

assistant: **Abstract**

The first objective is to develop a classification procedure combined with a conformity-of-production testing method. It will start from existing measurement methods, improve some of them and possibly develop new ones. The second objective is to test and specify road construction and maintenance techniques that would achieve satisfactory durability of the acoustic performances while complying with other requirements of sustainability like safety, pollution and mobility. The third objective is to develop a procedure for cost/benefit analysis of noise abatement measures. The fourth objective is to issue a European Guidance Manual on the Utilisation of Low-Noise Road Surfacing" to help decision-makers to rationally plan noise abating or preventing measures integrating low-noise surfaces with other noise control measures."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Mathematical Insights into Dynamics of Incompressible Turbulence' (MIND) targeting Horizon Europe.

assistant: **Abstract**

The unifying goal of the MIND project is to enhance the mathematical understanding of turbulence in incompressible fluid mechanics. Turbulence represents one of the most profound unsolved problems in classical physics, giving rise to numerous deep mathematical challenges. The research is structured around two major interconnected objectives. The first focuses on linear advection-diffusion equations with singular velocity fields, exploring key quantitative aspects such as mixing, enhanced dissipation, and anomalous dissipation. These mechanisms, often easier to isolate and study in linear systems, are crucial for understanding energy transfer and the development of small-scale structures in turbulent fluids. The second goal addresses nonlinear dynamics in incompressible fluid systems, particularly the Euler, Navier-Stokes equations and the Surface Quasi-Geostrophic (SQG) equation. The main focus will be on the study of weak solutions in relevant function classes and their behavior. We will concentrate on qualitative aspects such as well-posedness and uniqueness, as well as quantitative aspects like gradient growth and anomalous dissipation.


**Keywords:** Flows associated with nonsmooth velocity fields; Convex integration in fluid dynamics
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Solar Magnetic Eruptions: Understanding and Forecasting'.

assistant: **Objectives**

We propose a four-year project aiming to first, understand solar eruptions and second, help build a future capacity to predict them, thus contributing to the forecasting of the ever-changing space weather conditions. Inclement space weather has adverse consequences on exposed humans and technological assets in space and near-space environments, and sometimes even on ground-based facilities. As solar eruptive activity is predominantly magnetic in origin, the targeted research objectives will be achieved via a comprehensive, innovative analysis of solar magnetogram data combined with complementary information from other solar data sets. The proposed research topic presents a milestone for modern solar physics, thus carrying significant intellectual weight, and at the same time it may lead to meaningful practical improvements toward the safety and smooth operation of our manned and unmanned space infrastructure.The proposal coordinator has spent the past nine years in the United States of America, most of them as a Senior Professional Staff Physicist at the Johns Hopkins University Applied Physics Laboratory (JHU/APL) in Laurel, Maryland. As of September 2009 he possesses a tenure-track Assistant Research Professor (Researcher C') position at the Academy of Athens in Athens, Greece. He is also an elected Board Member of the European Solar Physics Division (ESPD; 2008 - 2011). With virtually non-existent institutional funding for travel, publications, and student supervision/mentoring, he applies for Marie Curie IRG funding primarily for these three purposes rather than for salary support. The proposal demonstrates that a Marie Curie IRG Grant will substantially improve his employment conditions and help him solidify his career prospects in Europe at the same time keeping h
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'The role of the non-canonical death receptor signalling in cancer and immune cells'.

assistant: **Innovation**

Immune surveillance refers to the ability of the immune system to efficiently induce cell death (apoptosis) in aberrant cells during the early stages of tumour development. This induction of cell death involves the binding of the death ligand TRAIL (TNF-related apoptosis-inducing ligand) to its death receptors (DRs) DR4 and DR5 on the target cell. However, tumour cells can escape this immune surveillance by switching the signalling downstream of DRs from the canonical pro-apoptotic signal towards a survival signal. Previous work from CHIRON partners highlights that this non-canonical DR-signalling regulates both tumour cell behaviour and immune cell functions, demonstrating its central role in understanding the tumour microenvironment. Yet, many aspects of the DR-signalling pathways remain unresolved, hampering the exploitation for diagnostic and therapeutic purposes. CHIRON will address these gaps via its main scientific aims: (i) to develop novel small molecule inhibitors (SMIs) to inhibit non-canonical DR-signalling (WP1), (ii) to identify new DR4- and DR5-binding partners within tumour and immune cells (WP2), and (iii) to gain a mechanistic understanding of the role of the non-canonical DR-signalling pathway in immune cells and cancer types (WP3). To achieve this, the CHIRON consortium combines the multidisciplinary and complementary expertise and resources of six academic and three private sector partners to (i) generate novel knowledge and innovative tools, (ii) strengthen an efficient network of knowledge exchange for further innovative synergies, and (iii) develop the expertise of early-stage and experienced researchers through excellent training. The outputs of the research will (i) develop novel tools to sensitise tumour cells for TRAIL-induced cell death, (ii
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Portable Luminescent Sensor for Volatile Organic Compounds' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

The LUMIVOCS project will exploit the recently developed luminescent Guest@MOF composite materials, which exhibit unique phototunable properties to engineer a revolutionary sensor device to achieve low concentration ppm-level detection of volatile organic compounds (VOCs). Such a compact VOC sensor could be deployed for toxic VOC detection in industry and sustainability applications, or, for use in diabetes diagnostics in the healthcare and biomedical sectors. Hitherto, none of the commercial VOC sensors in the market can fulfil the requirements of high sensitivity, high selectivity, and low cost all at once. The 18-month LUMIVOCS project will de-risk the proposed technology by delivering proof-of-concept data needed to move forward towards a commercial application. To this end, the major questions that will be addressed will encompass the following areas. (i) Engineering and prototyping of a compact VOC sensor device; (ii) Evaluation of detailed sensor performance; (iii) Assessment of sensor resilience against cross contamination and photobleaching; (iv) Manufacturability, sensor lifetime and mechanical resilience. The work will be conducted in collaboration with two industrial collaborators who will provide important technical input and will lend direction to the project to facilitate commercialisation.


**Keywords:** Luminescence,  Sensor,  Photonics,  Volatile organic compounds (VOC),  Metal-organic framework (MOF)
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'High Temparature concentrated solar thermal power plan with particle receiver and direct thermal storage'.

assistant: **Innovation**

According to the Integrated Roadmap of the Set-plan, and to reach the new EU target of 27% of renewable energies in 2030, there is the need to rapidly expand the use of all renewable energy sources in Europe to accelerate the fight against global climate change. This requires the acceleration of development of new options that are emerging today, particularly, technologies that solve the key issue of energy storage. The next-CSP Project is a response to this need and addresses significant improvements in all three elements targeted by the LCE-07-2016 call related to concentrated solar power: heat transfer fluids, which can be used for direct thermal energy storage; the solar field; and high temperature receivers allowing for new cycles. The proposed fluidized particle-in-tube concept is a breakthrough innovation that opens the route to the development of a new generation of CSP plants allowing high efficiency new cycles (50% and more) and 20% improvement of CSP plant efficiency. The Next-CSP technology that cumulates the know-how acquired during the CSP2 FP7 EU project on the particle-in-tube technology can be rapidly cost-competitive and introduced in the market. A cost reduction by 38% is expected with respect to current CSP electricity cost. The project will demonstrate at industrial pilot scale (TRL5) the validity of the particle-in-tube concept atop the Themis facility solar tower. A 4-MWth tubular solar receiver able to heat particles up to 800°C will be constructed and tested as well as the rest of the loop: a two-tank particle heat storage and a particle-to-pressurized air heat exchanger coupled to a 1.2 MWel gas turbine. A commercial scale power plant (150 MWel) will also be designed on the basis of experimental and simulation results and associated costs asses
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Reading Minds and Machines' (MindReading).

assistant: **Innovation**

Can we decode the training data of a Deep Neural Network (DNN) directly from its parameters?Training data of DNNs are assumed safe. Recent findings by us and by others indicate that this is not the case, with severe implications on Data-Privacy. Yet, such findings shed light on why DNNs perform so well.On a different front: Can we decode what a person saw/heard/thinks directly from their brain activity?This may have huge benefits: communicate with “locked-in” patients, explore dreams, man-machine interfaces, enhance our understanding of the human brain. No risk of violating human privacy here, as thoughts do not “float” in the air and person’s collaboration is required.Each of those 2 questions is intriguing on its own, with far-reaching implications. Despite the inherent differences between Human Brains & DNNs, they also have much in common. Exploring the two in-tandem can lead to significant breakthroughs in both fields. Recent advancements in both areas, with recent incorporation of Deep-Learning (DL) tools to analyze brain activity, opens the door to explore the two jointly. Our expertise in both domains will enable explicit Encoding/Decoding between Brain activity & DNN activations, allowing to directly learn/infer from one about the other. Initial explorations indicate that our proposed goals, although ambitious, are within reach. Our intermediate goals in each domain are worthwhile on their own, forming a strong safety net.Expected outcomes include:•Deep Data-Privacy•Insights on DNNs, their Generalization & Vulnerabilities•Insights on of “what is encoded where” in the brain•New scientific tools for brain-scientists to explore the brain •Allow “locked-in” (ALS) patients to communicate their thoughts/needs•Use Brain scanning to improve DNNs & DNNs to improve Brain