RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Switchable magneto-plasmonic contrast agents and molecular imaging technologies'.

assistant: **Innovation**

SWIMMOT will establish the scientific and technological basis for a radically new technique for in vivo molecular imaging based on a switchable contrast agent (CA) and corresponding optical imaging technology. Our CA will be based on novel magnetic core / plasmonic gold shell nanorods with specifically engineered biofunctional shells. We will develop a new magneto-plasmonic imaging technique based on magnetic excitation and plasmonic signal generation to realise multimodal optical coherence tomography / photoacoustic imaging modes. The magneto-plasmonic imaging technique will turn our CA on and off, which will allow complete removal of the imaging background. This discrimination of the background from the CA signal will yield ultra-high contrast molecular imaging. In addition, SWIMMOT, for the first time, will enable in vivo quantification of soluble biomarker concentrations and visualisation down to cellular resolution, which holds the potential to revolutionise molecular imaging and to surpass all current technological paradigms.These science and technology breakthroughs will enable detection of previously inaccessible in vivo physiology and molecular events, and elucidation of until now poorly understood biological mechanisms through studies in model organisms. This will in turn contribute to a better understanding of normal processes and disease pathogenesis. Thus, SWIMMOT will ultimately lead to earlier disease diagnostics for humans and to the development of new therapy concepts (including drugs). We will apply the SWIMMOT technology for diabetes research and will demonstrate its breakthrough potential for uncovering new biomolecular mechanisms in zebrafish model organisms.


**Keywords:** Optical imaging, contrast agent, magnetic, plasmonic, nanoparticle, biofunc
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Sixth Framework proposal on 'The evolution of cerebral asymmetry in Homo Sapiens'.

assistant: **Concept**

The essence of being human is the ability to communicate with language. This project addresses the questions what is the neural correlate of the capacity for language and what was the genetic nature of the transitions from a great ape-hominid precursor to modern H sapiens' Paul Broca's hypothesis that asymmetry (the torque") is the feature that defines the human brain will be investigated in skull and brain structure will be addressed. The project is informed by the hypothesis that a genetic determinant is located in a region of X-Y homology subject to change in the hominid lineage and that a series of changes in the Xq21.3/Yp sapiens-specific region of homology that includes the ProtocadherinX and ProtocadherinY gene pair influenced the timing and form of brain development. The project investigates these hypotheses through great ape-human comparisons of- skull and brain structure including asymmetries,- asymmetries of cellular structure of association cortex,- of the structure and organization of inter-hemispheric connexions."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'ClouT: Cloud of Things for empowering the citizen clout in smart cities' (ClouT) targeting Seventh Framework.

assistant: **Abstract**

ClouT's overall concept is leveraging the Cloud Computing as an enabler to bridge the Internet of Things with Internet of People via Internet of Services, to establish an efficient communication and collaboration platform exploiting all possible information sources to make the cities smarter and to help them facing the emerging challenges such as efficient energy management, economic growth and development. ClouT will provide infrastructures, services, tools and applications that will be reused by different city stakeholders such as municipalities, citizens, service developers and application integrators, in order to create, deploy and manage user-centric applications taking benefit of the latest advances in internet of things and cloud domains. ClouT with its user-centric approach, will also offer to end-users the possibility of creating their own Cloud services and share them with other citizens.<br/>ClouT will have the following major outputs: i) a smart city infrastructure with a near to infinity processing and storage capacity of data from trillions of things and people that are integrated via virtual services in the Cloud while keeping their universal interoperability; ii) a set of platform level tools and services aiming at facilitating IoT application development, deployment and supervision iii) secure data access and processing mechanisms that can handle big data acquired from the heterogeneous sources in quasi real-time;  iv) innovative city applications and field trials in four pilot cities: Santander and Genova in Europe, Mitaka and Fujisawa in Japan.<br/>ClouT will reduce costs and time to develop and deploy new applications by using new flavours of public-private partnerships inspired by the Cloud models, supporting win-win strategies for all stakeholders.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Innovative AI-based Ophthalmologic Diagnosis'.

assistant: **Innovation**

AiVision is a unique telemedicine cloud platform powered by deep learning AI that supports the diagnosis of sight related diseases. It is created with the objective of optimizing the detection and treatment of a highly probable cause of blindness in diabetic patients, known as diabetic retinopathy. Diabetic Retinopathy is the leading cause of blindness affecting the population that is less than 65 years old. After 15 years of significant improvements treating diabetes, 95% of type one diabetic patients and 60% of type 2 diabetic patients suffer from at least a mild and in some cases from severe diabetic retinopathy. In 2015, 415m people suffered from diabetes and this figure will grow up to 640m in 2040. There are 4,2M diabetics in the US, and around 24,000 new cases per year of advanced retinopathy due to diabetes.  AiVision intends to solve this health problem through an improved eye screening medical examination process facilitated by a telemedicine platform and automated algorithms that support diagnosis decision making.   We have gathered a database of more than 107,000 categorized eye fundus screenings which we have use in our algorithms, we have a partnership with the French Orthoptists Syndicate (with 1,000 professionals, it represents 90% of the sector) and are running our first paid pilots in France on 90 hospitals and health centres and working with the WHO in 4 African pilots.There is a clear willingness to pay from the market actors: orthoptist and ophthalmologists consider that the increase in screened patients will vastly contribute to early detection of signs of retinopathy, allowing for better treatment.AiVision is the core project of AiScreenings, a start-up founded in 2017 by partners with management, research, medical sciences and IT backgrounds. The
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'A European AI On Demand Platform and Ecosystem' (AI4EU), addressing dissemination and exploitation.

assistant: **Impact**

Artificial Intelligence is a disruptive technology of our times with expected impacts rivalling those of electricity or printing. Resources for innovation are currently dominated by giant tech companies in North America and China. To ensure European independence and leadership, we must invest wisely by bundling, connecting and opening our AI resources. AI4EU will efficiently build a comprehensive European AI-on-demand platform to lower barriers to innovation, to boost technology transfer and catalyse the growth of start-ups and SMEs in all sectors through Open calls and other actions. The platform will act as a broker, developer and one-stop shop providing and showcasing services, expertise, algorithms, software frameworks, development tools, components, modules, data, computing resources, prototyping functions and access to funding. Training will enable different user communities (engineers, civic leaders, etc.) to obtain skills and certifications. The AI4EU Platform will establish a world reference, built upon and interoperable with existing AI and data components (e.g. the Acumos open-source framework, QWT search engine..) and platforms. It will mobilize the whole European AI ecosystem and already unites 80 partners in 21 countries including researchers, innovators and related talents. Eight industry-driven AI pilots will demonstrate the value of the platform as an innovation tool. In order to enhance the platform, research on five key interconnected AI scientific areas will be carried out using platform technologies and results will be implemented. The pilots and research will showcase how AI4EU can stimulate scientific discovery and technological innovation. The AI4EU Ethical Observatory will be established to ensure the respect of human centred AI values and Europ
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Dynamics on homogeneous spaces, spectra and arithmetic', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

We consider the dynamics of actions on homogeneous spaces of algebraic groups,We propose to tackle the central open problems in the area, including understanding actions of diagonal groups on homogeneous spaces without an entropy assumption, a related conjecture of Furstenberg about measures on R / Z invariant under multiplication by 2 and 3, and obtaining a quantitative understanding of equidistribution properties of unipotent flows and groups generated by unipotents.This has applications in arithmetic, Diophantine approximations, the spectral theory of homogeneous spaces, mathematical physics, and other fields. Connections to arithmetic combinatorics will be pursued.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'STORAGE OF HYDROGEN: ALTERNATIVE PRESSURE ENCLOSURE DEVELOPMENT' (SH2APED) under Horizon 2020.

assistant: **Objectives**

The goal of the SH2APED project is to develop and test at TRL4 a conformable and cost-effective hydrogen 70 MPa storage system with increased efficiency and unprecedented safety performance. The innovative storage system is composed of the assembly of 9 tubular vessels fitting into a design space of 1800x1300x140 mm used for the battery pack. Fire resistance and mechanical robustness are drastically improved while the cost is decreased by 20% compared to the state-of-the-art Type IV tanks. This architecture allows a modular system configuration fitting into the flat space of light-duty car underbodies. All the vessel and the system elements are being manufactured using know-hows and high-throughput processes. Performance parameters and KPIs are monitoring in compliance with the current regulations, codes and standards (RCS) aiming the update of RCS by new knowledge and technological breakthroughs and simplification of certification. Economic assessment for industrial mass manufacturing is in line with the expectations of the automotive industry.The SH2APED consortium is a strong partnership of two industrials, one federal institute and one university. Optimum CPV - Plastic Omnium is the leader in hydrogen vessels fabrication for the automotive industry. Misal Srl is the highly skilled on mechanical components machining. BAM is the expert on safety and reliability of high-pressure composite cylinders. Ulster University is one of key providers of hydrogen safety research globally. In addition, a vital contribution to the project is expected from the Advisory Board comprising vehicle manufacturers including Daimler, Toyota, Audi, Geely, FIA, GreenGT. They will advise the project on the SH2APED system integration in light-duty fuel cell vehicles and validate the project res
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Exploring bacterial Quorum Sensing Infochemicals and hydrolytic Proteins linked to marine Particle degradation'.

assistant: **Concept**

The ocean is by far the largest reservoir for carbon dioxide (CO2) on Earth and represents a driving force for climate mitigation. Through photosynthesis, active marine microorganisms (e.g. phytoplankton) convert atmospheric CO2 into biomass, where the majority of it is cycled in the surface waters by diverse processes including bacterial respiration and hydrolysis. Some of this biomass is exported as particulate organic carbon (POC) into the deep ocean, where bacterial cells play a critical role in regulating the efficiency of carbon export because they colonize and enzymatically hydrolyze POC as it sinks . A recent study  suggested that signaling mechanisms within particle-associated bacterial communities enhance the activity of hydrolytic proteins involved in POC degradation. This overlooked process, known as quorum sensing, might impact the amount of carbon sequestered in the marine environment and ultimately affect the rate that CO2 is removed from the atmosphere.Quorum sensing (QS) involves the excretion and reception of distinct signaling molecules, but the biogeochemical implications of these bacterial “conversations” are poorly understood. To date, only a few culture-independent studies on QS in the marine environment have been carried out. This project will elucidate the role of QS systems among marine bacteria in triggering the synthesis of specific infochemicals and hydrolytic proteins, as well as its impact on shaping particles and particle-associated bacterial communities. Proposed methods include mass spectrometry, proteomics, three-dimensional particle imaging, molecular assessment of bacterial assemblages, and in situ localization of bacteria on intact particles. The outcome of the project will provide critical information on the importance of QS in reg
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Optimal design of frustrated self assembly building blocks' under Horizon 2020.

assistant: **Concept**

Nature's ability to organize building blocks into large structures of finite size has inspired many researchers to attempt similar constructs with synthetic subunits. DNA origami triangles are such synthetically built subunits capable to self assemble to shells of various shapes. Subunits and their interactions are typically designed so that they match the target shell geometry as much as possible. Such designs, however, require an increasing number of subunit types as the target shell complexity increases. Instead, we propose a computational scheme aimed to reduce the required subunit specificity in such assemblies, by relaxing the exact geometrical constraints on the target surface and exploiting subunit deformability. Two example structures will be considered, in both of which subunits are triangular and the assembly is stress mediated. The first one is an icosahedral structure of either of two sizes, both in a mechanically stressed state. Our aim is to find the appropriate subunit design which assembles both sizes with prescribed yields, from a single type of subunits, by adjusting the subunit's mechanical properties. The second structure is an ellipsoidal shell, which, again, we aim to assemble from a single species of subunits. Finite compliance allows subunits to adapt to the local geometry and coordination, however, the associated frustration raises the problem of controling long range elastic interactions and rules out naive subunit designs. As a solution, we propose an optimization approach to efficiently adjust the subunits' mechanical properties until a target free energy minimum is reached at the required sizes and shapes. We use a coarse grained triangle model with a grand canonical Monte Carlo scheme for equilibrium and dynamical simulations. Progressing
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Accelerated myocardial perfusion, metabolic and contractile cardiovascular magnetic resonance imaging' under Seventh Framework.

assistant: **Concept**

Cardiovascular disease (CVD) remains the leading cause of death worldwide and the costs due to CVD are increasing. Early detection and correct treatment of CVD is therefore important and research on cardiovascular magnetic resonance (CMR) for imaging of myocardial viability, perfusion and contractility has been intensified. While these methods are already well developed and in use in clinical research and practice, data on metabolic changes associated with CVD are difficult to obtain in-vivo due to the low inherent sensitivity of CMR. With the advent of hyperpolarization methods, an opportunity for probing metabolism in the in-vivo heart with high resolution has emerged. The hyperpolarization is short-lived, however, and requires imaging with high scan efficiency during a short time window.The objective of this research proposal is to develop in-vivo metabolic imaging by exploiting and furthering latest technology developed for CMR scan acceleration and carbon hyperpolarization at the University and ETH Zurich. Joint assessment of the interrelation of perfusion, metabolism and contractile function of the heart will be used to study occlusion and reperfusion in an animal model, triggered by the ongoing debate about the cause of reperfusion injury during treatment of CVD.The applicant already has expertise in accelerated imaging for human applications based on research projects he carried out in Sweden and Japan. He is now seeking to add experience in animal imaging and metabolic spectroscopic imaging methods to his repertoire. By joining one of the world-leading institutions in CMR research he will efficiently contribute and profit from a cutting-edge research endeavor aimed at extending the diagnostic capabilities of CMR. Upon completion of the project the fellow is exp
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'RESEARCHERS' NIGHT IN REPUBLIC OF MACEDONIA 2009' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

Project's general objective consists of developing and maintaining positive public relations among the research community and the wider population. Public perception of the researchers is the focal point of the event and it contributes towards its shaping in a positive way. The programme of activities will be varied and address to all age categories and groups of the population, regardless of their level of socio-economic background. Prior to the event itself, guided tours and promotional events will be held, while shows, exhibitions, hands on experiments, demonstrations and other activities for promotion of the researchers in three cities will be offered during the night itself. A European corner will emphasize the European dimension of the event, and winners of the Poster Competition will be rewarded. The event will be organised by the AEC with its three organizational units in Skopje, Bitola and Stip, In order to reach the general objective there are also several specific objectives related to implementation of this event: • To establishing a clear picture of the current state of affairs related to the public perception of the researchers in Macedonia; • To utilize the researchers’ experience for improvement of the aspect of public perception of their profession; • To diversify the focus groups, disciplines and scope of participants and to assure a massive public response. In order to reach these objectives the following actions will be undertaken during the implementation of the Researchers’ night project in 2009: • Effective awareness campaign; • Attractive activities during the night, and; • Measurable Impact assessment.