RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Probing the Structure and Dynamics of Water in its Various States'.

assistant: **Objectives**

We propose to address some of the most important outstanding questions for a microscopic understanding of water: What is the structure and dynamics of the hydrogen-bonding network that give rise to all the unique properties of water? How is the structure and dynamics affected by temperature, pressure and by perturbation through interaction with solutes and interfaces? Here we point to the opportunity to exploit the completely new avenues that the novel x-ray free-electron lasers open up for probing both structure and dynamics of water from hot temperatures down to the deeply supercooled regime where the anomalous properties become extreme. We plan to further develop fast cooling and ultrafast x-ray probing allowing access to below the homogeneous ice nucleation limit, to probe equilibrium dynamics through probe-probe techniques based on x-ray correlation spectroscopy, to access low-energy vibrational mode dynamics through THz pump and x-ray scattering probe and to transfer x-ray spectroscopies into the time domain.We will address one of the currently most debated issues related to a potential liquid-liquid transition and 2nd critical point in liquid water. The goal is to determine experimentally if water, as hypothesized in certain models, can really exist as two liquids, if there is reversible phase transition between the hypothesized liquids, evaluate if these hypothesized liquids can equilibrate on a time scale faster then the rate of ice nucleation and if there exists a critical point that can explain the fluctuations related to the diverging response functions. We will continue to critically investigate our proposed hypothesis that water at ambient temperature encompasses fluctuations around two local structures and that the dominating structure is a strongly disto
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'The computer-supported design of artefacts and spaces' will create measurable scientific, societal and economic impact aligned with Fourth Framework.

assistant: **Impact**

The overall objectives of both phases of this project are therefore:- to develop a computer-based environment integrating the design tools which already exist - such as CAD systems, graphics tools, hypermedia, simulation and rendering tools, etc., - into a collaborative environment, supporting the flexible informal practices of designers and the distributed physical spaces in which they work;- to develop a computer-based system supporting the interaction of designers with developers (marketing professionals, production engineers, etc.) and/or with users (fabricators, clients, etc.).Our approach to the research is an interdisciplinary one with two linked components. One concerns the analysis of the co-operative work involved in the design of artefacts and spaces. The other concerns the development of technical means for appropriately engaging and connecting this co-operative work. The principal methods to be used for the work analysis and the development of computer support will be ethnographic studies of work in context and participatory design. We will a) look at design practices in a variety of work settings, b) explore the technical and organisational possibilities for creating integrated electronic work environments, c) look at the potential of such an integrated environment for supporting a meshing of design practices with modern industrial paradigms, d) create a variety of 'product-oriented' technical ideas and test them in co-operation with end-users.We will use the first phase for:- conducting a series of pilot studies for assessing the feasibility of the overall project;- developing a shared understanding and conceptual framework;- developing co-operative relationships with end-users - practitioners of design, software companies who specialise in multi-media en
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Sixth Framework proposal on 'Human behavior through dynamics of complex social networks: an interdisciplinary approach'.

assistant: **Concept**

This project aims to further develop the basic science of complex social networks in a quantitative way, and apply our findings to the dynamics of human behavior. We intend to generalize and apply our results to a wider range of networks, including economi c, traffic, and environmental networks, thus establishing an interdisciplinary program of research based in complex social networks. Thus, the methods and techniques to be developed, based on Statistical Physics concepts, will be of further use in a variet y of other fields. To date, the application of complexity to the topology and emergent dynamic behavior in social networks has been mostly limited, qualitative, and rather empirical. We propose to use quantitative characterization of complex social network s by analyzing a number of real-world phenomena, including: crowd behavior, search strategies, traffic flow, dynamics of human relationship networks, spread of epidemics, as well as dynamic patterns in other disciplines, such as Economics and Finance, and Environmental networks. A principal goal is to characterize, optimize and control the structure, dynamics and flow in complex social networks, aiming to uncover the organizing principles that limit and influence the emergence of collective behavior in such systems. This work will also test the hypothesis that the dynamics of certain collective human behavior is governed by an underlying drive to optimize certain aspects of the underlying network on which this behavior takes place. Our studies will use exten sive real-world data of social nature, which will be collected in the frame of the project. The consortium will bring together scientists of various disciplines working in the emerging field of complex networks, in order to study topology and dynamics of s oci
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'GENetics and the Electrocardiogram for predicting Scd rISk' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Sudden cardiac death (SCD), a main consequence of malignant ventricular arrhythmias, is a leading cause of cardiovascular mortality in the general population. The early identification of individuals at risk is important. The spatio-temporal dispersion of ventricular repolarization is recognized as one of the major factors modulating the vulnerability to malignant arrhythmias and SCD. The morphology of the T-wave has been proposed to specifically reflect dispersion of ventricular repolarization. As part of my Ph.D, I developed a signal processing method to quantify the single-lead T-wave morphology restitution (TMR) index and I have shown that is strongly associated with SCD risk, but its relationship with intracardiac indices of dispersion of repolarization has never been evaluated. In addition, genome-wide association studies have been successful in identifying genetic variants for ECG indices in the general population, but  no previous publications have reported SNPs significantly associated with the T-wave morphology. The main objective of this project is to establish and test a novel effective approach to prevent SCD based on the combination of information derived from cardiac electrophysiological indices and genetic predisposition.The project has three parts: 1) To develop a novel ECG risk marker based on the adaptation of 3D T-wave morphological variations to heart rate changes with strong SCD predictive value. 2) To assess the interaction of non-invasive ECG indices with intra-cardiac electrophysiological indices simultaneously measured during invasive electrophysiological studies. 3) To generate personalized risk scores combining genetics, ECG indices and clinical variables to optimize SCD prediction. This project has the ambition of establishing a new approach
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Pathways to Alzheimer's disease' under Horizon 2020.

assistant: **Concept**

Critical to our understanding of Alzheimer’s disease (AD) and also to finding therapies is determining how key pathological factors interact and relate to neuronal toxicity, symptoms and disease progression. My research has focussed on amyloid beta (Aβ) moities and demonstrated that cerebrospinal fluid (CSF) Aβ42 correlates with cerebral Aβ pathology; that Aβ accumulates in the brain 10-20 years prior to onset of symptoms; and that CSF Aβ abnormalities precede CSF tau changes. However, it is increasingly clear that a simple linear model of AD aetiology and progression is inadequate. This proposal aims at developing and validating new diagnostic and prognostic biomarker tools to examine the AD pathogenesis in humans taking a broad view of AD’s multiple pathophysiological features and their putative biomarkers. The major questions, all relevant to therapeutic research, that will be addressed in my proposal include: (i) how are different forms of Aβ produced and modified; (ii) what is the toxicity of these different forms; (iii) how is this toxicity mediated; and iv) what other pathologies may contribute to or modify AD-like phenotypes? We and others have shown that Aβ monomers are relatively non-toxic. We will address the hypothesis that Aβ starts to accumulate in the brains of certain individuals due to defective clearance of the peptide. Once aggregated, Aβ acquires chemical modifications during brain incubation over years. These modified Aβ forms then induce tau hyperphosphorylation and concomitantly over-activate the immune system, resulting in neurotoxicity. Other pathologies, including α-synuclein and TDP-43, may contribute in this process. In PATHAD, we will develop and validate new diagnostic and prognostic tools using a combination of groundbreaking technologies
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Advanced optical materials and devices -3' under Fifth Framework.

assistant: **Concept**

AOMD-3 will continue the series of regular Baltic AOMD conferences ; the previous two were successfully held in Riga and Vilnius . This conference will pursue the tradition of exchange of ideas and cooperation between the East and West in the field of optical technologies , so enhancing integration of Newly Associated Baltic states into the European research activities. The main sessions will be on new inorganic and organic optical materials, semiconductors, smart materials and Nan technology, as well as on radiation effects and development of advanced optical devices (including new health care techniques and equipment) . The AOMD-3 topics are in accordance with the 5th Framework programme - key actions 1.1.2-4.8.4 (advanced opt-electronics and microelectronics), 1.1.2-6 (future and emerging technologies) and 1.1.3.-5 (RTD activities of a generic nature) .
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Mechanical torsional oscillations driven by the angular momentum of light' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

The ability of light to carry angular momentum has been the subject of an active scientific research since the beginning of 20th century, and yet the knowledge in this area still has many gaps and overlooked possibilities for technological innovation. In particular, a non-dissipative technology enabling an optomechanical transduction of the angular momentum irrespective of its spin or orbital nature is yet to be achieved. The project “OSCILLIGHT” offers an original solution to this problem by exploiting the inherent vector nature of angular momentum. During the two-year fellowship at University of Bordeaux (France), Dr. Georgiy Tkachenko (Researcher) guided by Dr. Etienne Brasselet (Supervisor) will realize proof-of-concept experimental demonstrations of the universal transfer of angular momentum that will lead to the implementation of a mechanical oscillator, whose size will eventually make it compatible with on-chip photonic systems. This work will therefore answer the key strategic orientation of the European Commission towards the development of digital, enabling and emerging technologies for micro/nanoelectronics and photonics.The proposed research is timely, as the scientific literature over the last 5 years has seen the increasing emergence of studies on integrated optomechanical devices, including those driven by angular momentum of light. After the last few years of the relevant preparatory work done by the Supervisor, his students and collaborators, the stage is now set for an effective implementation of this proposal, and the Researcher is the perfect candidate for the leading role to be played under the Supervisor’s guidance. Most importantly, the successful realization of this project will be beneficial to both the host university and the Researcher’s caree
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Cross-sector dialogue for Wildfire Risk Management' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

In line with increasing demands for more public participation, transparency and fairness in risk management institutions and procedures, FIRELOGUE aims to coordinate and support the Innovation Actions (IAs) by integrating their findings across stakeholder groups and fire management phases. It therefore builds on different formats to process the existing WFRM knowledge and innovations as developed by the IAs to translate them into the FIRELOGUE platform. The FIRELOGUE platform ? together with Communication Booster services such as brokering expertise ? will disseminate the insights and technologies developed by the IAs and integrated by the FIRELOGUE project. In addition to developing dedicated knowledge sharing formats for the exchange between the IAs, FIRELOGUE also aims to (1) deconstruct conflicting (and synergising) aims, interests, mandates, policies and practices existing in WFRM, (2) identify real or perceived injustices linked to these conflicts, (3) provide a space for deliberating on these conflicts and synergies in a just and inclusive way, in order to (4) co-develop integrated strategies to overcome these conflicts. FIRELOGUE builds on an Integrated Systems Thinking approach to bind the IAs together while comprehensively addressing the different components of wildfire risk (hazard, exposure, vulnerability and capabilities ) as well as the diverse natural and socioeconomic drivers of risk. Building on the concept of Just Transition, different notions of justice (distributive, procedural and restorative justice) will form the basis for structuring the discussions within and across the working groups. Collaborative governance will build the conceptual underpinning for designing the dialogue workshops and to eventually co-develop integrated WFRM strategies.


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system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'The basis of th2 induction by b cells' (1994-1998).

assistant: **Concept**

Research objectives and content It has been observed by Dr. Gray's lab and other laboratories that the type of cell presenting antigen to a T cell can influence the subsequent differentiation of the T cell. Dendritic cells have been shown to give rise to Thl type T cells (characterised by IFNg secretion), probably as a result of IL-12 secretion. B cells have the propensity to cause Th2 differentiation (producers of IL-4). The basis of this influence is not known In this project I will investigate the molecular basis of the very potent activity of B cells in the inducing Th2 cells. This activity is dependent upon expression of CD40 by the B cell. I will investigate, in in-vitro restimulation cultures (with anti-CD3) if the activity is mediated by a soluble or membrane factor and I will try to block the development of Th2 cells in the presence of B cells, with a variety of antibodies. I will carry out a systematic survey (by RT-PCR and bioassay/ELISA) of the cytokines that are produced following activation of B cells via CD40. In addition, I will help in the characterization of genes, isolated by differential display/subtractive PCR, that are newly-expressed following CD40 ligation of B cells. Training content (objective, benefit and expected impact) I will learn much about the late differentiation of B lymphocytes in the immune response and how they interact with T Lymphocytes. Both of these areas are outside my PhD project in which I studied very early B cell differentiation. I will also learn many new cellular and immunological techniques, as well as some new molecular ones (differential display). I will also gain experience working abroad and will have to present my work at conferences. The question of how T cells differentiate into Th1 or Th2 subsets is a very import
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Collaborative & Robust Engineering using Simulation Capability Enabling Next Design Optimisation' in the context of a Seventh Framework call.

assistant: **Objectives**

The IMG4 project CRESCENDO addresses the Vision 2020 objectives for the aeronautical industry by contributing significantly to the fulfilment of three specific targets of the aeronautical industry’s Strategic Research Agenda. CRESCENDO will develop the foundations for the Behavioural Digital Aircraft (BDA), taking experience and results from VIVACE, and integrating these into a federative system and building the BDA on top of them. Main components of the BDA are: the Model Store, the Simulation Factory, the Quality Laboratory, and the Enterprise Collaboration Capabilities. It will be validated through use cases and test cases concerning “Power Plant Integration”, “Energy Aircraft”, “Thermal Aircraft” and “Value Generation” design problems and viewpoints during the preliminary design, detailed design, and test and certification phases of a generic aircraft product life-cycle. The BDA will become the new backbone for the simulation world, just as the Digital Mock-up (DMU) is today for the Product Life-cycle Management (PLM) world. This is considered a challenging area for research and innovation for the next decade. Hence, the CRESCENDO results will provide the aeronautics supply chain with the means to realistically manage and mature the virtual product in the extended/virtual enterprise with all of the requested functionality and components in each phase of the product engineering life cycle. CRESCENDO will make its approach available to the aeronautics supply chain via existing networks, information dissemination, training and technology transfer actions. The project will be organised into six subprojects: four technical and business-oriented subprojects, one “Enabling Capabilities” subproject which will deliver the BDA and a sixth subproject, responsible for consortiu