RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Use of adenoviral vectors as an investigative tool in the study of human primary monocytes/macrophages' to be submitted under Fourth Framework.

assistant: **Abstract**

Research objectives and content Tumour necrosis factor (TNF) is a key factor in the pathogenesis of rheumatoid arthritis (RA) and other autoimmune conditions (reviewed in (1)). The major source of this cytokine is the monocyte/macrophage pool. The importance of TNF to RA has led to much interest in the intracellular molecular signaling mechanisms controlling its production, as this may give insights into the cause of its over-expression and identification of a means of correction. The majority of this research has involved murine cell lines. However, it would be more appropriate if this research was carried out in primary human monocytes and disease tissue. Unfortunately, it has not been possible to genetically manipulated these cells by transfection. The aim of this application is to develop, for the first time, human peripheral blood monocytes/macrophages as a system for studying the intracellular mechanisms controlling the production of TNF. To do this I wish to utilise of adenovirus transfection systems being developed at the Kennedy Institute to allow the easy genetic manipulation of human primary monocytes and to facilitate study of process controlling TNF expression in the most appropriate system for human disease. It will allow us to understand the mechanism controlling TNF production and identify molecular factors involved in the elevated levels observed in RA. Training content (objective, benefit and expected impact) - This training would teach us more about signalling in monocytes/macrophages and have amajor impact on our understanding of disease processes. - The knowledge already acquired in adenoviral transfection system at the Kennedy Insitute (KI)will enable me to rapidly use this advanced technique and the associated molecular biology skillsrequired. The
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Firm Dynamic Investments in Research and Development and Skills in Service Industries.' (INVPROD).

assistant: **Innovation**

Productivity growth is key to wealth and high living standards. For many years, Europe’s productivity growth has been declining and since 2005, falls below 1 percent. A possible way to raise productivity is to increase investments in intangible (knowledge based) assets such as workforce skills and Research and Development (R&D). To design policy measures that will effectively facilitate these investments and boost productivity growth, it is essential to understand the firms’ decision-making process in R&D and worker skills investments. In this project, I address the questions(1) What are the incentives each firm faces when making investment decisions in R&D and worker skills improvement? (2) What is the optimal level of investment for each firm? Moreover, what are the implications of these investments for the firms' longrun productivity development? I propose to develop and estimate a dynamic model of firm investment decision in R&D and worker skills improvement in the service industries. The estimation results will shed lights on firms’ investment incentives by quantifying the firm-specific longrun returns and costs to these investments. The estimated model predicts firm-specific responses to changes in their economic environment, therefore allows for ex-ante policy evaluation that aims at fostering productivity growth. In answering the questions raised, the project contributes to the knowledge on productivity and firm investments by providing insights on the (i) multidimensional productivity development in the service industries,  (ii) complementarity between different intangible assets such as R&D and worker skills, and (iii) firm decision-making process.


**Keywords:** Dynamic Investment, R&D, Employee Training, Service, Productivity
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Where are the Humanities in the Medical Humanities? How Comics Can Improve Healthcare Training, Practice, and Dissemination' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

The last decade has seen a steady increase in the number of medical schools offering courses in the Medical Humanities, an interdisciplinary field that promotes the study of the Humanities in healthcare education as engendering greater awareness in practitioners in training and thereby better healthcare practice and dissemination. While research in the field is rapidly developing, it problematically remains largely theoretical, based on a single case study, and/or presents Humanities scholarship as merely additive to rather than integrated in education. It is therefore crucial to comprehensively examine how the Medical Humanities works—and can work—in and through practice. This project will critically elaborate the benefits of further integrating the Humanities in the Medical Humanities by examining and expanding the discourse on Graphic Medicine. A flourishing field attentive to the study and production of comics about health and healthcare, Graphic Medicine utilizes theoretical and artistic research practice in productive reciprocal exchange. As such, it is well suited to evaluate and develop the aims, current applications, and potential of the Medical Humanities to positively affect not only healthcare scholars and practitioners, but also comics artists, patients, their families, carers, and the public. Through cross-national, cross-cultural, and cross-linguistic analyses of Graphic Medicine, from healthcare education to online information, and from individual artistic practices to collaborations between comics artists and healthcare institutions, this project’s five work packages will offer unprecedented comparisons and unprecedented reach to multiple stakeholders who can use the project’s findings for future research. In an era of global pandemic and rampant disinf
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fourth Framework proposal on 'Immunocytochemical and biochemical characterization of fmrp in neurons'.

assistant: **Innovation**

Research objectives and content The fragile X syndrome is the most common form of inherited mental retardation in man and is caused by a dynamic mutation in the FMR-1 gene, that it is located in Xq27.3. The mutational basis of the syndrome is an expansion of a trinucleotide repeat (CGG) just upstream of coding region. As a result, transcription suppression through hypermethylation of the promoter region occurs. Lack of the expression of the gene product, FMRP, is responsible for the pathogenesis of the fragile X syndrome. Thus far the physiological funcion of FMRP is unknown. An understanding of the function of FMRP would provide insight into the molecular basis of the fragile X syndrome.The goal of this study is further characterization of FMRP in neurons using different experimental approaches. Training content (objective, benefit and expected impact) Using biotinylated antibodies against FMRP I will study the expression pattern of FMRP in normal and transgenic mice, with special emphasis to the central nervous system. At the subcellular level I will study the routing of FMRP, using cultured neurons which are transfected with a plasmid containing either wildtype or mutant forms of FMRP.In addition, biochemical studies will be performed to characterize tne different molecular forms and possible interaction(s) of FMRP with other proteins or RNA's. Links with industry / industrial relevance (22)
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'The evolution of suprasegmental morphology in West Nilotic' (2021-2027) under Horizon Europe.

assistant: **Objectives**

NILOMORPH sets out to explain how linguistic evolution took a highly unexpected turn in one family of languages spoken in East Africa. They have evolved a morphological system where multiple grammatical categories are expressed simultaneously within a single syllable, through subtle modulations of its phonological properties. For example, in the Dinka language the word tèm, meaning ‘to cut’, can be made to mean ‘she cuts it for someone’ by lengthening the vowel, changing the low tone to high, and pronouncing it with breathy voice quality: té̤ːm, and more than dozen other contrasts can be generated by similar means. A sin-gle monosyllabic word in language like Dinka attains a degree of information density unparalleled else-where in the languages of the world. Surprisingly, comparative evidence suggests that the West Nilotic lan-guages were once much more conventional, using suffixes to mark grammatical categories. As has hap-pened in many other languages, such as English, these suffixes were lost over time. But rather than simply disappearing, they were transformed into suprasegmental phonological properties pronounced concurrently with the word stem. The aim of NILOMORPH is to reconstruct this evolution. But because of the extreme rarity of this morphological type, we need to explain not just how it happened here, we also have to explain why it did not happen in other language families. It is therefore not enough just to retrace the history of linguistic forms. NILOMORPH proposes a transformative step in historical linguistics: the reconstruction not just of external features, but of the cognitive motivation behind them. This will be achieved through the synergy of three teams, DESCRIPTION, MORPHOLOGY and RECONSTRUCTION, employing a combination of field linguistics, aco
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Tumor Regulation Assisted by Immunity and Nanotechnology' (TRAIN) under Horizon Europe.

assistant: **Objectives**

Cancer is the number one cause of death among Europeans under 65, being estimated that half of Europeans will develop cancer at some time in their lives. Despite the significant progress made in the prevention and treatment of cancer in recent years, this disease continues to claim lives and straining the European health and social systems and economies. In addition, cancer incidence and mortality are predicted to raise as consequence of the COVID-19 pandemic. To reduce these dramatic repercussions, innovative therapies, more effective and accessible to a wider population, are needed to treat patients with advanced cancer.The overarching aim of the TRAIN project is to leverage the enzyme activities in the tumor microenvironment to boost the efficacy of cancer immunotherapies via molecularly engineered peptide nanomaterials capable of metabolic modulation of tumors and release of chemotherapeutic drugs. TRAIN is focused on pancreatic adenocarcinoma (PAAD) and will develop biomimetic 3D PAAD models to test the proposed combined chemo- and immuno-therapy. The feasibility of this major goal will be achieved through a multidisciplinary approach that will employ concepts from peptide nanotechnology, enzymology, immunology and cancer biology, together with cutting-edge materials science, proteomics and cell biology methods.TRAIN is in line with “The Europe’s Beating Cancer Plan”, aimed at reducing the negative impact of cancer for patients, their families and healthcare systems, and addressing cancer-associated disparities across countries, while providing training and career development opportunities for a young and creative researcher at the intersection of peptide nanotechnology and cancer immunology.


**Keywords:** Peptides, enzyme-sensitive nanobiomaterials, (immuno)ther
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Take-up activities by universities of specific guidelines and recommendations to implement their modernisation agenda' (EUIMA).

assistant: **Innovation**

The project addresses two main elements of the modernisation agenda for Europe’s universities (i) the sustainability of university funding, financial management and development of full-costing and (ii) the transparency and appropriateness of measurement tools for the assessment of university-based research reflecting the diversity of university missions. A third “transversal” focus running through the project in addressing these two main issues will be to identify requirements for further development of human resources and management in universities to enhance the attractiveness of university careers. It deals directly with the aims of the work programme in providing support for mutual learning, exchange of experiences by universities of guidelines and recommendations from European Commission Expert Groups on the impact of external project-based funding on the financial management of universities, and the assessment of university-based research. The project will draw upon related empirical evidence from several projects conducted by the European University Association with its individual and collective membership and in partnership with other European associations representing the business communities, regional agencies and non-governmental bodies. As a European approach, the “take-up” activities will provide a crucial comparative framework in which to promote the modernisation of universities. The European Research Area requires a globally competitive European university sector as a main stakeholder that needs funding mechanisms which support its sustainability and research assessment indicators that respect the aims and objectives of chosen strategic missions and measures their excellence on these terms. Through a series of workshops and study visits held at different
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Commercial feasibility assessment of the first single-photon detector for CT' (PICOPROP4CT), addressing dissemination and exploitation.

assistant: **Impact**

The reduction of radiation exposure in Computed Tomography (CT) remains a pressing medical need in radiology and a major growth opportunity for the medical imaging industry. As part of our ERC research, we have identified a novel method to produce crystalline, photo-sensitive nanowires. These nanowires show a remarkable sensitivity, nearing single-photon detection; about 100 times better than current detectors. This could cause a seismic shift in medical imaging as it will drastically increase the safety of CT and open up many new applications for CT as a modality.In this project, we will assess the commercial feasibility of this novel detector. As part of this study we will investigate the scalability of our technology and characteristics of the market and will develop and implement a sound business strategy.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'WindScanner.eu - The European WindScanner Facility' (WINDSCANNER) under Seventh Framework.

assistant: **Objectives**

The future high rate of deployment of renewable energy will require a substantial increase in the installed wind power capacity towards 2020 and beyond, in fact this demand corresponds approximately to the installation of one large turbine every hour for the next decade. This is a substantial “grand challenge” as outlined in the Strategic Energy Technology Plan (SET-Plan) from 2009, which is the technology pillar of the EU’s energy and climate policy. The new WINDSCANNER research infrastructure facility has been conceived in the logic of the SET Plan and the vision of the European Innovation Union (Europe 2020 Strategy). The WINDSCANNER aims to enhance the European competitiveness in the wind energy sector and maintain European technological leadership in detailed high-resolution remote sensing measurement methodologies of wind and turbulence for wind energy.This ESFRI WindScanner Preparatory Phase (PP) project develops the governance scheme, legal model, and the final technological design and associated budget and financing models for its construction by 2016. The WINDSCANNER PP project will address coordinated European development of the facility in a joint technological and economically substantial European approach.The operational WINDSCANNER facility will be designed around:A central facility with the functions of handling the data management, hosting servers, hosting of website, administrative office, training of technicians and researchers who will operate the WindScanners, training of users, etc.Anticipated 6 new partner nodes equipped with mobile WindScanners used at existing or planned test facilities all over Europe (in different climate conditions and terrains)This WINDSCANNER facility will underpin the European Energy Research Alliance (EERA) Joint Program
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'First-principles engineering of thermal and electrical transport at the nanoscale'.

assistant: **Objectives**

There is great hope to tackle serious global issues related to energy consumption and waste by developing technologies based on efficient nanoscale materials and devices. For this to happen, we need breakthroughs in our ability to control electrical and thermal transport at the nanoscale. Ab-initio materials modelling will play a central role in this, providing microscopic understanding and the materials parameters needed to bridge the macroscopic performance and the microscopic mechanisms that determine transport properties. In this project I will use ab initio techniques based on density-functional theory to calculate the electronic and vibrational properties of materials as well as the carriers' relaxation times due to carrier-carrier and carrier-defect interactions. These are the key ingredients that will then be used in the Boltzmann transport equation to simulate transport in devices, taking into full account the coupled electron-phonon dynamics in complex geometries, and in the presence of interfaces or defects. The research will proceed in three main directions. First, toward engineering materials and devices for high-performance nanoelectronic applications. Here I will study the detailed mechanisms of carrier-induced heating in silicon- and carbon-based electronic devices: this is a key technological issue that is becoming dominant as we race toward the nanoscale. Second, toward identifying new optimal thermoelectric materials, which are of great relevance to energy conversion or cooling applications. To this end, I will perform a systematic study of the thermoelectric properties of promising materials, starting from ternary and filled CoSb3-based skutterudites. Third, toward characterizing structural and spectroscopic properties of materials and devices. Here