RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'a user-friendly procedure that analyses genomic, clinical and demographic data to generate a personalized report with statistical analysis on the efficacy of antidepressants and their side effects' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

The World Health Organization recognizes mental disorders as one of the most significant public health challenges worldwide as measured by prevalence, burden of disease and disability , and depression as the world’s leading cause of disability. In EC  and WHO  action plans it is clearly requested that mental health services can be accessed without unfair financial barriers and that treatments are made available on criteria of both efficiency and financial fairness. In this framework personalised medicine is the fastest, most economic and optimized solution to the depression treatment problem. Indeed, the current push for a cost effective personalised medicine based on IT solution will also help with the commercialisation of our Predictix platform. The platform will allow medical practitioners to have up-to-date and accurate knowledge on each case and improve the care that patient receives, with an economic revenue too. Our solution allows for better delivery of available treatments – noted as a vital factor for increasing remission.  TALIAZ was founded in 2012 by Dr. Dekel Taliaz and Oren Taliaz. Our mission is to set a new standard in personalized medicine improving quality of life for patients suffering from depression. Taliaz takes advantage of in-house expertise in genetics, data science and central nervous system related disease with the advancements in genetic sequencing and machine learning technologies, to develop leading personal medicine proprietary IP solutions for depression. Our future vision is to use Predictix™ also as a decision support tool for common health concerns such as ADHD and Anxiety. The SME Instrument project now perfectly fits our strategy and vision by enabling a fast finalisation of the platform development and by providing us the resources
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Low cost pre-impregnated composite materials to achieve lower cost large structures such as wind turbine blades', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

The scientific and technical objectives of this research proposal concern the identification of suitable materials, formulations and processing techniques to reduce the cost of using prepregs. Research is required to formulate resins and develop fabrics with a view to achieving a lower cost and low toxicity hot melt impregnation process which has low scrap yield but minimises cure times, consumable usage and labour for the end user.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Atomic-Level Physics of Advanced Materials' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

Most of the technological materials have been developed by very expensive and cumbersome trial and error methods. On the other hand, computer based theoretical design of advanced materials is an area where rapid and extensive developments are taking place. Within my group new theoretical tools have now been established which are extremely well suited to the study of complex materials. In this approach basic quantum mechanical theories are used to describe fundamental properties of alloys and compounds. The utilization of such calculations to investigate possible optimizations of certain key properties represents a major departure from the traditional design philosophy. The purpose of my project is to build up a new competence in the field of computer-aided simulations of advanced materials. The main goal will be to achieve a deep understanding of the behaviour of complex metallic systems under equilibrium and non-equilibrium conditions at the atomic level by studying their electronic, magnetic and atomic structure using the most modern and advanced computational methods. This will enable us to establish a set of materials parameters and composition-structure-property relations that are needed for materials optimization. The research will be focused on fundamental technological properties related to defects in advanced metallic alloys (high-performance steels, superalloys, and refractory, energy related and geochemical materials) and alloy phases (solid solutions, intermetallic compounds), which will be studied by means of parameter free atomistic simulations combined with continuum modelling. As a first example, we will study the Fe-Cr system, which is of great interest to industry as well as in connection to nuclear waste. The Fe-Cr-Ni system will form another large gr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Deterministic processes, community organisation and ecosystem function' (FUNCTION), addressing dissemination and exploitation.

assistant: **Impact**

The impact of global change on biodiversity loss has major implications for ecosystem functioning and human well-being.  Ecosystem functions such as decomposition of plant litter are emergent properties of the plant litter faunal community. Research into the relationship between the attributes of a community (e.g. diversity) and the emergent functions of that community (e.g. decomposition), otherwise known as the diversity-function relationship, has predominately used manipulative or reductionist experiments to identify mechanisms that drive function. In order to manage natural resources for ecosystem service delivery however, we need to understand the diversity-function relationship in natural ecosystems. This project will use community phylogenetic structure to explore deterministic processes driving plant-litter arthropod community organization, and examine the influence of community organisation on plant-litter decomposition and nutrient flux using stable isotopes to characterize resource use. Both will be achieved using a unique and highly resolved natural experimental system on Little Barrier island, New Zealand.The project Dr Griffiths proposes will benefit from training she will receive in (a) bioinformatics and phylogenetics, (b) stable isotope approaches to quantifying cryptic food webs, and (c) plant nutrient composition. The value of these multiple disciplines will be advanced through integration into an ecosystem functioning framework using Dr Griffiths’s established expertise. This mutually beneficial project will promote long-term collaborations. The training will add considerable value to the future research areas Dr Griffiths intends to address; enhancing ecosystem functioning and services in managed and natural ecosystems. The European Research Area wi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Landscape development, biodiversity and co-operative livestock systems in europe' (LACOPE).

assistant: **Concept**

European biodiversity significantly depends on livestock systems. 15 to 28% of endangered species are living mainly in grazed steppe-, tundra-, heath, dry grassland and marsh habitats. In most countries grazing is/was organised in permanent or seasonal co-operations (land-owner/land-user agents). A process of dissolving of co-operation forms affects marginal regions, remote from market places or disadvantaged according to productivity. The commitment of biodiversity conservation of the EU-member states embraces to a large extent thecae of landscape and regional development (e.g. AGENDA 2000, NATURA 2000).Effects of market policies, eastern enlargement of the EU, CAP-reform etc. are often mismatched with conservation goals. The main objective of the proposed research project is the improvement of the ecological and economic effectiveness of co-operative livestock systems which contribute to biodiversity conservation.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Global Justice and the Remittances Challenge: Confronting the €1 trillion “gap” in the literature' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Remittances are the single most important source of global relief for the world’s poor, exceeding €1 trillion annually. Remittances outstrip Official Development Assistance by a factor of four and, in 2018, surpassed Foreign Direct Investment for the first time. 1 billion people are directly involved in the remittances economy, including 200 million senders and 800 million receivers. The benefits of remittances for receivers and their communities are broad and deep. Remittances support basic nutritional needs, housing, healthcare, and other critical daily expenses. Often these subsidies are lifelines without which receivers would be destitute. Remittances also improve childhood educational attainment levels, support local and state development and democracy, and serve as insurance against natural and political disasters. One would expect that GJ theory would be analytically able to incorporate remittances and normatively keen to explore the vast potentials for real-world injustice alleviation inherent to them. However, that is not the case. Just the opposite. Liberal GJ theory usually ignores remittances or frames them as harmful, and denies—sometimes denigrates—the agency of remitters. To sloganize: 1 billion people and €1 trillion are missing from the GJ debates. Worse, liberal GJ theorists endorse policies that could reduce remittances and increase harm. What is called GJ is often experienced by the world’s poorest as manifest injustice. JUSTREMIT investigates the paradigmatic constraints which make this injustice inevitable and invisible to liberal GJ theory. Then, using both theoretical and ethnographic studies, it constructs an alternative paradigm that rectifies that injustice by putting remittances and the agency of the global poor at the centre of the new parad
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'Action of hypothalamic nEuropeptides on anteriorpituitary folliculostellate cell function in acute pituitary slices'.

assistant: **Objectives**

Research objectives and content The anterior pituitary gland has been referred to as the ' master' gland in that it secretes hormones in response to the input of l hypothalamic clocks which in turn control the physiology of a wide variety of organs. Dr. Mollard's group recently has shown l that the pituitary is partitioned into distinct assemblies of endocrine cells that pace synchronously their cytosolic calcium transients, key elements of the stimulus-secretion coupling. The working hypothesis is now that other cells (e.g. the network of: gap junctional coupled folliculostellate cells) might pace collective rhythms within the anterior gland despite the apparent wide' range of distances between the active endocrine cell domains. I propose to use the acute slice preparation applied to bothnormal and generated knock-out mice in combination with 3D real-time confocal calcium imaging and immunofluorescent stainings to investigate whether the stimulation of FS cells with PACAP, a hypothalamic neuropeptide, would trigger waves in cytosolic calcium that would spread, not only into the FS cell network, but also to distinct endocrine cell domains. Extensive analysis of this putative mode of cell-to-cell communication would be of particular interest, insofar that long-distance I synchrony may be an important determinant for shaping the patterns of hormone release.  Training content (objective, benefit and expected impact)  The work will be carried out at the INSERM unit 469 (Director: Dr. C. Barberis, Supervisor of the applicant: Dr. P. Mollard) | which is a department of the CNRS-INSERM Centre of Pharmacology-Endocrinology (Director: J. Bockaert), a leading I research center in the field in Europe. I should benefit from the suggested proposal in a number of ways. It will allow
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Lightning inhibition for protection of urban soft targets and critical infrastructure against lightning strikes.' (LightningPro), addressing dissemination and exploitation.

assistant: **Impact**

Since 1752, when Benjamin Franklin carried out his famous experiment with a kite, science has not gone much further in protection agains. Lightning strikes. Lightning Rod manufacturers have centered attention in obtaining maximum benefit from the so named Franklin–Rod, developing devices with greater lightning attraction to try to maximize the probability that the lightning will strike on it. Prototal has gone one step forward, developing the Inhibitor Lightning Rod to provide infrastructure and urban areas protection against lightning strikes, by means of a primary protection element, which impedes the creation of the conditions that produce a lightning strike, within the protected area. The Inhibitor Lightning Rod deionizes the environment, so the beam is not repelled elsewhere, but it simply doesn’t get formed; the beam formation is inhibited. Our company, has been working in the sector of lightning protection since 1993. We have installed more than one thousand Inhibitor Lightning Rods with the 100% of success rate against lightning strikes. Currently, we want to develop a second generation of our product, having a bigger coverage area, a better design, reducing the cost of manufacturer process and including technical tests that confirm our technical specifications and clients’ requirements.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'The Environmental Exposome And Health' (ENVESOME).

assistant: **Innovation**

ENVESOME aims to elucidate mechanistically the role of air, noise, light, and hazardous waste pollution in non-communicable disease development. The project addresses the need to strengthen the knowledge available to policymakers regarding pollution-disease associations and causal mechanisms at different phases throughout the human lifecycle. ENVESOME proposes to develop an exposome and citizen-science-based framework for assessing the risks of emerging environmental health stressors. This will be achieved by fusing environmental monitoring and personal exposure data and models through AI tools. Human and cell biology knowledge, human biomonitoring, and in vitro data will be used to determine adverse outcome pathways and networks associated with environmental stressors. Particular focus will be paid to intersecting pathways relevant to cardiorespiratory disease; metabolic syndrome; neurotoxicity; immunotoxicity; sleep, and mental health disorders. We aim to elucidate the main sources of environmental exposure and drivers of the adverse outcomes above. This will allow for the articulation of cost-effective mitigation strategies that will be applied in select case studies. Their efficacy will be evaluated using environmental and exposure indicators together with early effect biomarkers (EEB). Methodological and technical innovations and the respective scientific evidence regarding the causal links between emerging environmental stressors and human health will be translated into policy proposals supporting the articulation of strategies for country- or city-specific, targeted and cost-effective interventions, thus promoting effective public health protection, as well as guidelines and updated limit values as needed. Environmental management for public health protection wil
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Sixth Framework proposal for the project 'Regulation of gene expression during liver development'.

assistant: **Objectives**

The main goal of this proposal is to understand the epigenetic mechanisms involved in the establishment and propagation of active chromatin states of genes during embryonic and postnatal liver development. The proposal is focused on a novel concept, put forward by the host group's previous studies, which suggest the generation of a poised, or committed state of active chromatin early during hepatocyte differentiation.The research plan includes genome-wide gene expression analysis and biochemical approaches for chromatin structure and function studies in conjunction with DNA and RNA fluorescence in situ hybridization (FISH) assays. Besides wild type animals we also plan to study specific KO mice. While the host group has strong expertise in chromatin analysis using biochemical approaches it lacks the required experience in embryology, gene disruption and molecular imaging technologies. We seek to gain these latter expertise through the transfer of knowledge from recruited experienced researchers.The host group will provide state of the art facilities and training in the field of gene expression and chromatin research. The project is expected to provide new insights into the poorly understood mechanisms involved in epigenetic regulation of active chromatin states. It will also have a great impact to the host in terms of enhanced competitiveness in the field of epigenetic research, technological competence and increased cohesion with European research.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Functional differentiation in response to environmental variability in two contrasting shrub line species of high-altitude Himalaya' in the context of a Horizon 2020 call.

assistant: **Objectives**

The major aim of the proposal is to obtain novel insights into the ability of plant species to adapt to changing climatic conditions by exploring their functional differentiation along natural gradients. Specifically, I propose to elucidate adaptive strategies of long-lived shrub-line forming species with contrasting strategies to changing climatic conditions (in natural experimental settings). The study will allow disentangling the independent and combined effects of temperature and water availability on functional traits (morphological and biochemical) without confounding effects of other factors. The study will also enable to analyse the direction and magnitude of shift in trait values (as per trait driver theory) along climatic gradients and elucidate the relative role of various factors (e.g. climatic, spatial, organisational) causing functional trait variability (e.g. intra-individual to inter-population). We will get insights into specific traits that are favoured at particular climate (e.g. at colder and drier, colder and wet etc.). Further, combination gradients and virtual transplant experiment will allow to verify the direct link between species traits and climatic conditions, at short and long temporal scales, respectively. In addition, the project will allow to test if the functional responses of single species to climatic variability can be generalized to whole communities.This fellowship will be a perfect stepping stone in achieving my career goal to become a researcher at the top of the interdisciplinary field of population and community ecology in climatically heterogenous and diverse high elevation ecosystems. My quality as a researcher will be improved by the new skills and deepened knowledge that I will acquire at the Institute of Botany of the Czech