RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Membrane activity of amyloid fibrils: unravelling cell killing mechanism' (AMYLOID) under Seventh Framework.

assistant: **Objectives**

Numerous pathological conditions, designated as misfolding diseases, involve conversion of specific proteins from their native, soluble state to highly ordered filamentous polymers. For many years these amyloid fibrils were considered to be inert end-products of the aggregation pathway, while the toxic properties were mainly attributed to soluble oligomeric intermediates. A recent study demonstrated that fully assembled amyloid fibrils induce cell death, and the observed toxic effects are inversely correlated with fibril length (Xue at al. J. Biol. Chem. 2009, 284, 34272-34282). The findings pointed out that membrane damage may be involved in the cell injury, however the detailed mechanism by which fibrils kill cells remains to be resolved.The proposed research is one of the first studies aiming to shed light on this important question through systematic investigation of fibril-membrane interactions. Specifically, screening distinct lipid components will be performed in order to allocate membrane binding to specific cellular targets. The impact of fibrillar dimensions on the membrane activity of the aggregates and their interactions with specific lipid components will be evaluated. Additional factors, such as pH and protein charge, will be investigated. The study will include several amyloidogenic proteins in order to assess the generic nature of the killing mechanism.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Nanotechnology-enabled deep profiling of the blood and brain proteome at the intersection of neurodegeneration and neurooncology' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

NanoNeuroOmics ambition is to bring together nanotechnology, proteomics and blood biomarker discovery at the emerging intersection of neurodegeneration and neurooncology. NanoNeuroOmics proposes a nanotechnology-based innovative solution for the integrative profiling of the blood and brain tissue proteomes to address two interconnected challenges: i) The unmet clinical need for early diagnostic and disease-monitoring blood biomarkers for two of the most challenging Central Nervous System disorders, namely Alzheimer’s disease (AD) and Glioblastoma (GBM); and ii) The AD-GBM ‘inverse comorbidity’ knowledge gap and intriguing molecular interrelation. NanoNeuroOmics presents a novel approach, in which nanoparticles are employed as scavenging agents to uncover brain disease-specific protein markers in blood, otherwise buried under the overwhelming signal of highly abundant molecules. NanoNeuroOmics aims to tackle the technological challenge of discovering highly specific blood biomarkers, by longitudinally tracking blood and brain proteomic signals at different stages of disease progression. To leverage its full potential, the proposed research programme combines longitudinal preclinical studies with human patient clinical validation studies. Such multi-dimensional proteomic approaches are expected to pioneer new blood biomarker discoveries and to provide mechanistic insight into the comorbidity of neurological diseases. NanoNeuroOmics attempts to discover a distinct set of dysregulated proteins for each of AD and GBM independently and to unveil overlapping molecular pathways to explain the AD-GBM inverse comorbidity. In a broader context, NanoNeuroOmics aspires to bridge the gap between brain pathophysiology and molecular alterations in the blood, across the biological conti
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Dance Heterotopias: (un)making race and gender boundaries through social dances in Cape Town' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

DanceTopias proposes to analyse the production and transformation of identity boundaries which occur through social dances in African globalized cities, through an analysis of the case of Cape Town. In this city, as in others, social and popular dances create spaces where citizens can assert, transform, and play with identity categories and social norms related to race, class, and gender. In that sense, they represent what Michel Foucault called “heterotopias”, i.e. spaces that disrupt ordinary time. Through a qualitative methodology and an interdisciplinary analysis connecting anthropology, history and geography, DanceTopias will analyse the transformation of spaces and identities through social dances, with a focus on race and gender. This project is structured around three main objectives and methodological entries:1. To trace the history of social dances in Cape Town;2. To provide an ethnography of identity boundaries created through dance;3. To map the global dance networks connecting Cape Town to the world.My research will be conducted through a 21-month outgoing phase at the University of Cape Town, a 3-months secondment at UCL (London), and a 12-month return phase at the University of Geneva. The combination of the anthropology of globalization, the approach on identity boundaries, and the geography of dance spaces will offer an original perspective on the understanding of African urban societies. DanceTopias will also reveal a rarely discussed aspect of contemporary South Africa: it will focus on certain areas of subversion of racial and gender boundaries, where we observe dialogues between social groups and categories that were previously divided by Apartheid. Beyond South-Africa, this analysis on transgressive dance spaces will provide insightful theoretical
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Resource Preservation by Application of BIOefFECTORs in European Crop Production'.

assistant: **Concept**

BIOFECTOR is an integrated project that develops alternative fertilisation strategies by the use of various bio-effectors (BEs, plant growth promoting microorganisms and natural extraction products). BEs stimulate root growth, solubilise and mineralise sparingly available nutrients, or protect plants from abiotic and biotic stresses. Novel BEs will be isolated, characterized and applied in strategic combination with alternative fertilisation strategies that include organic and low-input farming, use of waste recycling fertilizers, and fertiliser-placement technologies.Bio-effectors addressed comprise fungal strains of Trichoderma, Penicillium and Sebacinales, as well as bacterial strains of Bacillus and Pseudomonades with well-characterized root growth promoting and nutrient solubilising potential. Natural extraction products of seaweed, compost and plant extracts, as well as their purified active compounds are also tested in various combinations. Maize, wheat and tomato are chosen as representative crops. Laboratory and European-wide field experiments assure product adaptation to divers geo-climatic conditions. Viable alternatives to the conventional practice of mineral fertilisation are developed, towards environmental friendly agricultural practice with reduced agrochemical input.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Fighting with a Smile: Satirical and Humourist Voices of Resilience from Hindi Speaking Subaltern Subjects and Communities' under Horizon Europe.

assistant: **Concept**

The project aims to be the first attempt at investigating the forms, uses and functions of Hindi contemporary humour (hasya) and satire (vyangya). By moving towards this direction, it will focus especially on the connection of Hindi satire with the claims by the subaltern and marginalized subjects and communities of Hindi contemporary public sphere. It must be outlined that the terms subaltern and marginalized will refer not only to the Adivasi - framed by Indian constitution as the 'tribals' of India - and to the Dalit - better known as the 'outcaste'people - but also to the LGBTQIA+ and to the discriminated women in India. In the light of the above, the main objective of theresearch is to shed light on the narratives of dissent pursued by these subjects and communities. It will also analyse the contributionof Hindi satirists and humourists to specific socio-cultural and political claims and initiatives. Finally, it will investigate the use of satire and humour as a personal and collective forms of resilience. To achieve these set goals, the project surveys in a interdisciplinary way many fields in which satire can be detected. Primarily, it focuses on the use of satire in Hindi contemporary literature. In this field the research highlights the contribution of Surya Bala, usually deemed as the first Hindi woman literary satirist. Other less famous marginalized literary contemporary satirists will be equally taken into consideration. Moreover, it must be stressed that, apart from the literary side of satire, the project will investigate also the 'life' beyond literature of satire. In this field, it will focus primarily on the performative uses of satire and humour during the Hasya kavi sammelan (Meeting of humorist poets) which are usually held in many parts of North-In
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Researchers Night 2006 in Gliwice Re-search IT in your life!""', explaining its relevance to EU policy priorities under Sixth Framework.

assistant: **Impact**

Learning is also fun, and scientists love playing and know how to play. These will be the two main theses of the Friday Researchers Night??? on 22 September 2006 in Gliwice. While organizing the event, we have assumed that IT technologies, being the object of research carried out by scientists from our Department, are omnipresent.At the same time, we find it necessary to popularize knowledge related thereto among persons who are not connected with science, including especially the youth. We will prove that issues accompanying technical thoughts of the contemporary world may be pleasant and not that complicated. We will present microprocessors in an exciting and amusing manner based on subjects relating to: molecular biology, medicine, criminology, art, mass media, sport and space travels.Program is rich in scientific contests for the general public, interesting lectures, sports competitions, multimedia presentations, interactive games, concerts, etc. since it was prepared on the basis of young people's ideas. Participants of particular exercises will demonstrate their knowledge, intelligence, physical fitness, and creativity. We will establish an opportunity for presenting various skills, ensuring a high level of emotions at the same time.The superior goal of the event will be, however, the meeting of the public with researchers, who will turn their attention to the attractiveness of scientific career in a colourful and legible for everyone manner. "Stepping down the chair", they will discuss their non-scientific passions. We believe that this will be an inspiration for young people trying to find their place in the present world.The professional organization of the event is guaranteed by world-known scientists. Innovativeness of the Gliwice Researchers Nigh t will enco
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Optimizing dna based vaccination against fmdv in sheep and pigs' (FMDNAVACC).

assistant: **Innovation**

The final objective of this proposal is to develop optimised strategies of DNA vaccination to foot-and-mouth disease (FMD) in sheep and pigs, for potential use as vaccines including those for  emergency" depending on EU policy of FMDV eradication programmes. One of the major advantages of DNA vaccination over current inactivated vaccines is the avoidance of the costly manipulation of infectious virus in high containment facilities and the risk of infection in the animal due to insufficient inactivation. The ways by which the FMDV DNA vaccine strategy will be optimised will include a comparison of the immunogenicity in sheep and pigs of different FMDV antigens, of a new generation of plasmids, of promising adjuvants for DNA vaccines, of parenteral versus nasal routes of administration and of prime-boost regimens. The protocols giving the best immune responses will be used to evaluate protection to FMDV challenge in sheep and pigs."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'All Solid-State Multi-Photon Generation and Quantum Manipulation at Room Temperature', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Quantum computation promises an exponential acceleration of certain computational tasks, most notably, the factorization of large numbers. One of the main schemes proposed for the realization of a quantum computer is linear optical quantum computation (LOQC). In this scheme, the quantum information carriers are photons, and the computation takes place by their propagation through optical devices that change their respective states, followed by the measurement of their final state.For robust manipulation of the multi-photon states, integrated photonic circuits have been recently introduced. Up till now, however, all experimental demonstrations of multi-photon manipulation with these devices used up to four photons, due to the difficulty to create many identical photons at once.This is since the current single-photons sources are all random, having success probabilities lower than one , and thus the probability of simultaneous emission of N such sources  decays exponentially with N. The exponential speed-up promised by quantum computation algorithms is therefore canceled-out.One way to overcome this could be the use of quantum-optical memories. These devices can store single photons for a pre-determined period of time. N such memories, storing N photons from one single-photon source, and releasing all of them at once, would constitute an N-photon source which rate is just N times slower than that of the single-photon source feeding it. In comparison to the use of N probabilistic single-photon sources in parallel, this constitutes an exponential improvement.Here, we propose the development of a diamond-based, all-solid-state, room-temperature multi-photon source, composed of one single photon source and several single-photon memory units. This source could then feed a phot
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Boosting motor learning through sleep and targeted memory reactivation in ageing and Parkinson’s disease' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Rehabilitation is an important therapeutic strategy for patients with Parkinson’s disease (PD), whereby motor adaptations are learned to maintain daily functioning. However, patients often present difficulty consolidating newly learned skills into long-term memory, which reduces the benefits of training. Interventions that enhance consolidation are therefore projected to diminish the impact of PD. Sleep facilitates motor memory consolidation in healthy adults, especially in combination with targeted memory reactivation (TMR). TMR works by adding associated auditory stimuli during learning, which are replayed during sleep and thus reinforce the recently formed neural connections. Importantly, recent work has suggested that consolidation during sleep may be preserved in PD, but robust findings are lacking and have not involved TMR. This knowledge gap is astonishing given the potential benefits that can be gained by integrating sleep interventions into rehabilitation. My objective is to address this imperative by investigating the effect of sleep on motor memory consolidation by experimentally manipulating exposure to sleep and TMR for the first time. Concretely, I will compare the effect of a 2-hour daytime nap with or without TMR to that of a wake control period in PD and age-matched controls. I will use a validated motor sequence task to test for behavioral markers of motor learning and apply state-of-the-art neuroimaging techniques to study the imprint of neural network changes underlying consolidation. My training objectives include teaching and supervising students in rehabilitation–related neuroscientific topics and research leadership development. I will also implement a rigorous dissemination and communication plan to achieve optimal societal impact of my research
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for '“(De) Securitising Muslims in Cyber space:  Social Media, Civil society and Marginalisation  After Charlie Hebdo and the Islamic State”' under Horizon 2020.

assistant: **Concept**

DSMM proposes a two-year fellowship at the CNRS in Aix-en-Provence, France, with a six month secondment at the School of Oriental and African Studies in London, UK. Europe faces one of the most significant security issues of recent years in the threats posed by Islamist terrorism. Prominent in this, and little researched, is the role of social media in this process. The project aims to fill this gap by applying cutting-edge research in a vital field for the future of Europe in assessing the effect of social media narratives on the (de) securitisation of Muslims in France and the UK. It does this through taking an original and interdisciplinary approach, incorporating quantitative and qualitative methods and concepts from sociology, political science and media studies. The key research objective is to create an analytical account of the means by which social media narratives work to construct and deconstruct Muslims in France and the UK as security threats. This account draws on data from a range of social media platforms, in addition to interviews of key actors in France and the UK. In terms of outputs, the project will generate 3 peer reviewed articles. In addition, the work will be presented at international conferences and will feature in blog posts and policy briefs.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'European Platform and Roadmap for Future Public Safety Communication' (NARTUS) under Sixth Framework.

assistant: **Objectives**

The SSA project proposal NARTUS is focused on creating a European Public Safety Communication Forum which will establish a European platform and roadmap for future public safety communication and will help to facilitate European integration in the area of Public Safety with particular focus on public safety communications and information systems.The European Public Safety Communication Forum will include Conferences and will carry out other activities between the Conferences, designed to be interactive and consultative with public safety users, system providers and operators in as many European nations as possible.Through the Forum Conferences and other consultative mechanisms, NARTUS will not only establish consultation processes and build consensus, it will also disseminate information, best practice and establish protocols through which it will be able to provide advice to policy makers and influence the development of standards for the benefit of public safety in Europe.<br/>Once established, it is anticipated that the Forum will endure after the conclusion of the Project and will continue to build on the work completed during the Project lifetime.