RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'AdviSor neTwork foR OptimAl ferTilisers Use' to be submitted under Horizon Europe.

assistant: **Abstract**

STRATUS, extending over 60 months, aims to connect advisors across Europe for accelerating knowledge creation and sharing on Integrated Fertilization Management, supporting farmers to bring this knowledge into practice to achieve the ambition of the Farm to Fork and Biodiversity Strategies, thus reducing nutrient losses to the environment while maintaining soil fertility. For this, STRATUS will create an EU-wide advisory network through the creation of three transnational sub-networks (Fertilization Innovation Networks - FIN) on Precision farming, Bio-based fertilisers and Soil quality (SQ) in which trained advisors will collect a total of 104 Good Practices (GPs) and Research Innovations (RIs) on optimal fertiliser use and will identify at least 48 Best Practices (BPs) as the result of the systemic feasibility assessment of the GPs and RIs . In addition,  STRATUS will also ensure the integration of the advisors in the MS AKIS as well as the adaptation of the project work to the local conditions through the creation of 10 Communities of Practices (CoPs), in 10 partners countries, established with local AKIS actors, following the MA approach. Based on these BPs, STRATUS will develop 60 demonstrations and training material that will facilitate advisors to exchange knowledge, experiences and key challenges for advisory practice through Cross Visits in all MS and CoPs. All the knowledge generated in the project will become available through an inventory hosted in the digital platform of the STRATUS project. STRATUS will determine the model for the exploitation model of the platform besides the self-sustainability of the EU-wide advisory network .STRATUS will cover all EU27 MS, eleven (11) MS are covered directly by project partners, while the other are covered through being
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Bioartificial liver in vivo' under Fourth Framework.

assistant: **Concept**

Research objectives The development of a liver support system for the treatment of patients with fulminant hepatic failure and as a bridge to liver transplantation is a major challenge. Many early attempts focussed on broad detoxification based on the assumption that liver failure could be reversed if the associated toxins were removed from the circulation of the patient. Although improvement of the neurologic status of the patients has been reported, none achieved long term survival. It was therefore concluded that an effective liver support system should be able to perform the liver's multiple synthetic and metabolic functions including detoxification and excretion . The most logical approach to this problem is the introduction of active functioning hepatocytes. Different bioreactor systems are currently under investigation. However, an ideal BAL system has not yet been invented. We deviced a novel bioreactor (patent pending) which allows individual perfusion of high density cultured hepatocytes with low diffusional gradients, thereby more closely resembling the conditions in the intact liver lobuli. The bioreactor consists of a spirally wound nonwoven polyester matrix, i.e. a sheet-shaped threedimensional framework for hepatocyte immobilization and aggregation, and of integrated hydrophobic hollow-fibre membranes for oxygen supply and CO2 removal. The bioreactor is seeded with 220.106 freshly isolated porcine hepatocytes cultured at 20.106 viable cells/ml. Medium (plasma in vivo) is perfused through the extrafibre space and therefore in direct hepatocyte contact. In vitro evaluation of the BAL showed that hepatocytes contained cytoarchitectural characteristics as found in vivo and an even distribution of small hepatocyte aggregates ( < 75 fm) throughout the three-dim
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Cultural Heritage Outreach in RomAnce Languages' (CHORAL) targeting Horizon Europe.

assistant: **Abstract**

The Cultural Heritage Outreach in RomAnce Languages programme (CHORAL) is naturally linked to the enlarged European Alliance University UNITA, that brings together the universities of Turin and Brescia (Italy), Savoie Mont Blanc and Pau et Pays de l’Adour (France), Beira Interior (Portugal), Timisoara and Transilvania Brasov (Romania), Navarra and Zaragoza (Spain). These universities i have a strong track record of participating in international networks, joint research programs, educational and innovation projects. They also share a strong common heritage linked to Romance languages speaking populations (French, Italian, Portuguese, Romanian, and Spanish). In this context, a dedicated Cultural Heritage Hub (CHH) has been created to establish a research network within the Alliance structuring its research ecosystem facing cultural related challenges. This Alliance aims to become a key player in the construction of the European Higher Education and Research Area by developing an integrated European University that combines education, research, and innovation, with a focus on research areas that are strategic for the economic development of their territories. The CHH hopes to raise awareness and find solutions to societal challenges that the European Union is currently facing in order to strengthen rural territories, empower cross-border mountain communities, and reduce inequalities between the core and its peripheries. In a context of current crisis, and as natural borders have always been used to unite or divide communities, the challenges facing European Cultural Heritage are numerous so that a common training has become crucial. CHORAL doctoral programme will allow to progress in building a real community and sharing knowledge within UNITA CHH. This will be achieved b
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Screening and Functional Analyses of Photoreceptors in Extremophilic Microbial Communities'.

assistant: **Concept**

The High-Altitude Andean Lakes (HAAL) in the South American Puna-High Andes” are an almost unexplored ecosystem of shallow lakes at altitudes from 3,000 to 6,000 m above sea level. Although exposed to a broad range of extreme conditions they harbour an abundant microbial biodiversity that thrive in environmental conditions of high resemblance to those present in Earth`s early atmosphere. As part of our team in Argentina I have investigated this wide-ranging diversity by culturable and non-culturable methods:  so far we have assembled a collection of 200 extremophilic strains from shallow waters, sediments, flamingo faeces and even stromatolites (the only modern stromatolite-ecosystem on Earth recorded at such hostile environments!).The HAAL are clearly conditioned by the high intensity of UV irradiation - in addition to further extreme conditions (e.g. hypersalinity, drastic temperature changes, desiccation, high pH). The rich microbial diversity found in these lakes points to the presence of outstandingly active DNA repair systems - topics of  high interest for colleagues worldwide investigating biomass for energy research.  Unfortunately our scientific methods are limited - and thus I would like to use the expertise and excellent equipment at the host institute to investigate extensively the strain resistance mechanisms towards UV. These studies on indigenous extremophiles will provide important information about early life – but clearly are of biotechnological and astrobiology interest too.The research will focus on screening and molecular analyses of blue-light driven enzymatic activities such as photolyases involved in DNA-repairing systems - and in particular from the HAAL stromatolite-ecosystems. Their further overexpression and functional study will lead to thei
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'next Generation AutomotIve membrane electrode Assemblies'.

assistant: **Objectives**

GAIA has the overall aim of developing high power and high current density automotive MEAs well beyond the current state of the art up to TRL5. This project, encompassing OEMs, leading industrial and academic/research organisation/research institute partners with long expertise in fuel cell science and technology, and building on best developments from the FCHJU, will not only provide significantly higher performance MEAs but will also ensure the designs satisfy the cost, durability and operational targets set by the call.Accordingly, the specific objectives of the project are to:- Develop world-leading components (electrocatalysts, membranes, gas diffusion and microporous layers) and improve the interfaces between them to minimise resistances;- Realise the potential of these components in next generation MEAs showing a step-change in performance that will largely surpass the state of the art by delivering a beginning of life power density of 1.8 W/cm2 at 0.6 V;- Validate the MEA performance and durability in full size cell short stacks, with durability tests of 1000 h with extrapolation to 6,000 h;- Provide a cost assessment study that demonstrates that the MEAs can achieve the cost target of 6 €/kW for an annual production rate of 1 million square metres.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Foundation of Nonrelativistic String Theory and Its Applications to Holography' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

One of the most profound problems in modern theoretical physics concerns the formulation of quantum gravity. A predominating paradigm for addressing questions in quantum gravity is string theory. One important lesson from string theory is that different string theories must be unified in a nonperturbative theory called M-theory, to probe which corners of string theory with significant simplifications are valuable to consider. Notable examples of such corners are AdS/CFT duality and Matrix theory, with numerous applications to the information paradox in black hole physics, heavy-ion collisions in nuclear physics, superconductors in condensed matter, etc. The project focuses on a self-contained corner in string theory that treats space and time differently and has a nonrelativistic (NR) spectrum. This corner is called NR string theory. I will study the foundation of NR string theory and its relation to nonperturbative methods in string/M-theory. I will also explore applications to NR field theories, with impacts on condensed matter theories of ferromagnetism and 2D systems of electrons. During my PhD at UC Berkeley (US) and postdoc at Perimeter Institute (Canada), I  collaborated with some of the world experts in the field and sophisticated my expertise for this project. The host institution, Nordita, hosted by Stockholm University and KTH, provides an excellent environment for cutting-edge research on fundamental physics. The expertise among faculty members and postdocs, and the stimulating and extensive international visitor program at Nordita make it an ideal place to conduct this project and to sharpen my interdisciplinary skills in condensed matter and pure mathematics. In addition to my North American background, I also have long-term collaborations with research gr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Roles of non-coding RNAs in translational regulation during root developmental adaptation to phosphate starvation'.

assistant: **Concept**

The sessile lifestyle of plants requires them to adapt their growth and development to environmental variation. This implies a tight spatiotemporal regulation of gene expression to control developmental responses. Translational control, the regulation of the initiation, elongation or termination of ribosomes on an mRNA, provides cells additional mechanisms to rapidly control gene expression in a reversible manner, in response to environmental and developmental cues. It is known that non-coding RNA (ncRNA) can modify spatiotemporal gene expression patterns, and play a key role in developmental plasticity. Their role in the regulation of initiation of mRNA translation have been described in animals and hinted in plants, where mechanistic details are limited. Improving tolerance to nutrient deficiency is a major goal of agricultural research. Improvement of inorganic phosphate (Pi) starvation has been the target of classical breeding and genetic engineering. ncRNAs (i.e. miRNA399) have been shown to regulate root development during Pi starvation in roots of the model plant Arabidopsis thaliana. The three objectives of this project are to (a) analyze the role of translational control at the genomic level in response to Pi starvation using state-of-the-art methods that resolve ribosome activity to the codon level; (b) to assess the role of diverse classes of ncRNA in translational regulation in response to Pi starvation; and (c) to delve into the mechanistic role of selected ncRNAs in translational regulation during Pi starvation Towards these goals, we will isolate ribosomes specifically from root meristem cells and translation will be analyzed using genomic and bioinformatics approaches, The outcome will be identification of mechanisms of translational that control root de
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Selective and clean processes for the side chain oxidation of alkylaromatics by means of heterogeneous catalysts' in the context of a Fourth Framework call.

assistant: **Objectives**

BE95-1169 Selective and Clean Processes for the Side Chain Oxidation of Alkylaromatics The major objective of this project is the development of new processes to achieve the side chain oxidation of alkylaromatic compounds, which may yield different types of oxygenated organic chemicals (alcohols, ketones, aldehydes, carboxylic acids, anhydrides and epoxides) with a large number of industrial applications as intermediates in the manufacture of plastics, fibers, pharmaceuticals, agricultural chemicals, etc. At present, these oxidation reactions are commercially carried out by processes with important objections: formation of effluents causing environment pollution problems, use of corrosive conditions and low to moderate selectivities when synthesizing partially oxygenated chemicals, such as ketones and aldehydes. The key of the new oxidation processes will be based on the use of new heterogeneous catalysts, that will be prepared by supporting and isolating transition-metals on micro- and mesoporous solid matrixes, mainly zeolitic materials, in order to get high catalytic activity and selectivity towards the target products. The processes are also expected to present advantages compared to the conventional ones in terms of raw material utilization, energy consumption and environmental impact. The project will involve both laboratory and bench-scale research phases including economic and environmental evaluation and comparison with conventional oxidation processes. The partners involved include researchers from universities, research institutes and industry. The adequate balance present between academic and industrial partners will lead to a synergic effect to develop the project taking into account complementary points of view.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Directed self-assembly and micro-rheology of  colloidal Janus rods' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

Colloids with shape anisotropy and directional interactions promise to spontaneously assemble into a host of novel materials with unprecedented structures and properties, with bottom up control. Such colloids may display new physics in their crystallization, glass formation and gelation. They may in their self-assembly even show  behavior analogous to (bio)molecules. These new building blocks are therefore increasingly attracting attention from materials science, chemistry, physics and biology. Due to the low yield of most Janus particle syntheses, studies on self-assembly have largely been restricted to single clusters in the dilute limit. This significant hurdle will be overcome by the high yield method we developed recently, and we propose to investigate bulk self-assembly of Janus rods, of which one end is magnetically functionalized . In particular, we will investigate the phase behavior as a function of volume fraction and size ratio of magnetic to inert part using 3D confocal microscopy. Furthermore, we will investigate how these particles respond to external magnetic fields and what novel structures, dynamics, and mechanical properties (probed by optical-tweezers-assisted micro-rheology) may emerge.   This will for the first time extend the research scope of anisotropic Janus particles to topics that have traditionally been explored only for isotropic colloids.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'ImmortaSTEM: Transient Immortalisation for Patient Stem Cell Expansion and Therapeutic Application' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Under an ERC Advanced Grant, and subsequent PoC grant, Professor Shakesheff's team have invented a new intracellular delivery system that overcomes a problem in drug delivery in stem cell culture as well as regenerative medicine and other therapeutic approaches. The system, called GAG-binding enhanced transduction (GET), enables intracellular delivery of proteins, nucleic acids and particles into cells that resist other non-viral strategies. The work under ERC Advanced Grant and PoC funding has allowed exemplification of the delivery of proteins that promote pluripotency or differentiation, and delivery and expression of mRNA This ImmortaSTEM: Proof-of-Concept Application will achieve 7 deliverables that together will generate a robust business plan for commercialisation of a specific application of GET to aid cell therapy attempts. This is a unique approach allowing expansion of a patient’s own cells as a therapy. We will begin by performing a comprehensive market analysis to test our view that GET could be used to expand valuable cells presently defined as challenging or impossible. Next we take account of the market analysis to refine our technical work resulting in a report that provides robust evidence of market required advantages of GET over competitor products for stem cell expansion. This technical work will include a consideration of manufacturing routes and costs of goods. In parallel with the technical work we will commission an independent freedom-to-operate report. Finally, we will initiate confidential discussions with potential partners and customers via face-to-face meetings in Europe and the US.The final business plan will establish the technical and commercial feasibility of our approaches in one or more of our target markets. We envisage that at the