RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'The Climates and Habitability of Small Exoplanets Around Red Stars', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

The detection of life beyond our Solar System is possible only via the remote sensing of the atmospheres of exoplanets.  The recent discovery that small exoplanets are common around cool, red stars offers an exciting opportunity to study the atmospheres of Earth-like worlds.  Motivated by this revelation, the EXOKLEIN project proposes to construct a holistic climate framework to understand astronomical observations in the context of the atmosphere, geochemistry and biosignatures of the exoplanet.  The proposed research is divided into three major themes.  Research Theme 1 aims to construct a virtual laboratory of an atmosphere that considers atmospheric dynamics, chemistry and radiation, as well as how they interact.  This virtual laboratory enables us to understand the physical and chemical mechanisms involved, as well as predict the observed properties of an exoplanet.  Research Theme 2 aims to generalize the carbonate-silicate cycle (also known as the long-term carbon cycle) by considering variations in rock composition, water acidity and atmospheric conditions.  The carbonate-silicate cycle is important because it regulates the long-term presence of carbon dioxide (a vital greenhouse gas) in atmospheres.  We also aim to investigate the role of the cycle in determining the fates of ocean-dominated exoplanets called “water worlds”.  Research Theme 3 aims to investigate the long-term stability of biosignature gases in the context of the climate.  Whether a gas uniquely indicates the presence of biology on an exoplanet depends on the atmospheric properties and ultraviolet radiation environment.  We investigate three prime candidates for biosignature gases: methyl chloride, dimethylsulfide and ammonia.  Overall, the EXOKLEIN project will significantly advance our underst
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Decolonising madness? Transcultural psychiatry, international order and the birth of a global psyche in the aftermath of the Second World War'.

assistant: **Concept**

This project will provide crucial insights into the debate on the universality and cross-cultural applications of the notions of mental health and illness by offering the first and inter-disciplinary account of the historical origins and development of the concept of ‘global psyche’ and transcultural psychiatry. It will offer the first historical analysis of the colonial and post-colonial roots of the current global mental health movement, and the first systematic account of the decolonisation of psychiatry and mental health sciences. It will argue that the concept of universal, global psyche emerged in the aftermath of WWII and during decolonisation, when Western psychiatry strove to leave behind its colonial legacies, and lay the foundation for a more inclusive conversation between Western and non-Western mental health communities. In this period, leading psychiatrists across the globe set about identifying and defining the universal psychological mechanisms supposedly shared among all cultures (and 'civilisations'). I will explore this far-reaching psychiatric, social and cultural search for a new definition of 'common humanity', which developed in an increasingly inter-connected and culturally diverse global context, and examine the historical forces that drove it. I will also examine how the profession negotiated the tensions between researching cultural particularities and developing new, cross-cultural models of the mind. The project will answer some of the core questions related to this transformative period: How did psychiatrists and anthropologists from all over the world re-define the relationship between culture, race and individual psyche following the end of the Second World War and colonialism, what was the role of experts from the Global South and Easter
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Settling of a hollow precast concrete product aimed at the carrying out of reservoir structure bottoms' (1994-1998) targeting Fourth Framework.

assistant: **Abstract**

The principal centres of research and development in storm water management highlight the ever growing problems caused by rainy events. The proposal intends to design and develop a precast concrete product for improving performance in urban flood control, pollution minimization and stormwater harvestings in urbanized areas. The basis of the approach is, firstly, systematic technical review of existing realisations concerning the Reservoir Structures, followed by integration of the needs and requirements into the development of a new solution using precast-concrete elements. The project aims at the settling of a precast-concrete product that would have a vacuurn ratio about equal to 60, (that means 600 liters of water stored inside 1 m3 of pavement), and that would not be too expensive, in order to reach the largest market. The project will result in the testing on-site of the solution developed by the partners.The innovation of the project consists in the use of the precast-concrete material. It enables to overcome the limits and to improve the performances of the classical used materials (rough gravel and honeycomb structure in plastic material) as described in the State of the Art and Degree of Innovation ( 1.2 of the proposal). This project is very important for SMEs in the southern part of Europe and hundreds of SMEs of those countries could be interested in the results of this project. The SMEs, from the precast concrete industry, are manufacturer of precast-concrete products, then they will be able to manufacture the new product to be developed after a two year period of further development needed after the end of the project. They will also be able to carry-out the new structure, targeting then a new opening market
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'CNC dynamic mold for producing freely curved glass panels' to be submitted under Horizon 2020.

assistant: **Abstract**

Although the development of computing tools has been quite successful, the development of cost-effective, high speed and sustainable production processes for complex curved glass panels lags behind. In this integral innovation project, Free-D Geometries B.V. (Free-D) will bridge this gap by developing a highly advanced CNC dynamic mold prototype for production of curved glass panels: the Dynamic Glass Mold. This active pinbed with embedded transforming technology enables manufacturers to add freely doublecurved panels (3DC panels) to their product range, while highly optimizing the existing single curved panel production and logistics.Free-D will partner with a glass manufacturer for developing the mold technology. Selling or licensing the technology to firms working in other regions will subsequently be considered. Secondly, Free-D will intensify its collaboration with SMEs in specialized markets. The modular, cost-effective, easy-to-maintain, high resolution production system with multi-actuator units can also be applied for many other materials. The glass manufacturing sector will be engaged with highest priority. The production technology of Free-D will enable computer-controlled mass production of uniquely formed 3DC glass panels. Curved glass panels will find many uses: from yachts to entire building envelopes. This technique will be a game-changer, pushing innovation in a wide range of sectors. Spill-over effects to other sectors of industry will be achieved, for example where transforming requires very high-resolution bending under high-temperature production environments. The key aim of this feasibility study is to establish:1)a partnership with a glass manufacturer for prototype demonstration.2)a business plan.3)feasibility of the production of the advanced CN
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Concerted Action for Research into Myopathies due to Enzyme Deficiencies' (CARMEN).

assistant: **Innovation**

- To collate information on the rare metabolic myopathies- To establish an Internet presence for ready access to this data- To provide a forum for exchange of ideas and methodologies- To provide access to DNA probes and primers for study of these conditionsCARMEN will direct attention to a group of rare muscle diseases that arise from defects in the enzymes of muscle energy metabolism. The common feature of these diseases is that disruption of the mechanisms that deliver energy to the contractile apparatus leads to an exercise intolerance and rhabdomyolysis. The similarities in clinical presentation can cause complications in diagnosis, but implies that there may be some common strategies for treatment or therapy. CARMEN will gather information on these patients through a novel database, maintained on a central server and accessed through the Internet by any member of the CARMEN (http://carmen.bi.umist.ac.uk). The database will also be used to disseminate new technologies and inform about developments. In addition, workshops and short-term study exchanges will be used to develop methodological capabilities and act as a focus for new pan-European collaborations on these conditions. The pooled patient information, coupled with shared capabilities and skills, will accelerate and give added dimensions to research in this group of myopathies. Access to diagnostic probes, antibodies and primers will facilitate molecular diagnosis. Studies arising from CARMEN will benefit from the critical mass of subjects that is sufficiently large to be informative but which in addition, may identify additional factors that contribute to clinical heterogeneity. The CARMEN partners are recognised as centres of excellence with considerable experience in these myopathies. However, CARMEN is str
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Non-Food Crops-to-Industry schemes in EU27'.

assistant: **Objectives**

The ultimate objective is to explore the potential of non-food crops, which can be domestically grown in EU27 context, for selected industrial applications, namely oils, fibers, resins, pharmaceuticals and other specialty products and outline and prioritise crops-to-products schemes, suitable for the different Member States, which will support sustainable, economic viable and competitive European bio-based industry and agriculture.  The proposed project will be carried in 8WPs.  WP1 will report on non-food crops for selected industrial applications. Information will refer to main physical traits, cultivation areas, inputs, supply and logistics, yields, quality issues. WP2 will identify current molecular genetics technologies and suggest their potential applications in a crop-specific manner to address a wide range of breeding constraints. Improvement of non-food crops will entail breeding for agronomically important traits i.e yield and tolerance to abiotic and biotic conditions.  WP3 will explore the potential and feasibility of the European industry to make high-value biobased products from non-food crosp and biotechnological routes. WP4 will perform supply chain cost analysis, identify best business opportunities, and assess the socio-economic impacts of selected crop-to-product schemes at EU-27, regional and country levels. WP5 will assess selected production and environmental impacts and identify a ‘core’ list of standards and criteria for the environmental and socio-economic sustainability of selected crops-to-product schemes in a global and country-specific perspective. WP6 will perform an integrated technical, environmental, and economic assessment to help selecting and prioritising non-food crops. WP7 will address dissemination issues.  The expected output is t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Modeling, Simulation and Control of Multi-Physics Systems' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

This proposal is aimed at developing and analyzing a fundamentally new interdisciplinary approach for the modeling, simulation, control and optimization of multi-physics, multi-scale dynamical systems. The new innovative feature is to generate models via a network of modularized uni-physics components, where each component incorporates a mathematical model for the dynamical behavior as well as a model for the uncertainties, e.g. due to modeling, discretization or finite precision computation errors. Based on this new modeling concept also new numerical simulation, control, and optimization techniques will be developed and incorporated, that allow a systematic adaptive error control (including the appropriate treatment of different scales,and the uncertainties) for the components as well as for the whole multi-physics model. In order to cope with the  differential-algebraic and multi-scale character of the systems we will develop and analyze remodeling techniques for the components as well as for the whole network including the uncertainties and special structures. The new remodeled systems will be designed such that they allow an efficient and accurate  dynamical simulation with high order numerical integration techniques as well as efficient methods for model reduction and open and closed loop control.In an interdisciplinary corporation with colleagues from computer science and engineering we will extend the modeling language MODELICA to be able to incorporate the new features (in particular the uncertainties and modeling errors) and we also plan to implement the complete approach as a new software platform.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Superior Semiconductor mid-infrared Lasers' under Fifth Framework.

assistant: **Concept**

The aim of the project is to exploit fully the technological potential of quantum cascade lasers and open the way to entirely new mid-infrared applications, conceivable only if implemented with high performance mid-ir semiconductor sources. Quantum cascade lasers, based on intraband transitions, form a new class of devices, which are revolutionizing the world of mid-infrared sources. To date, QC lasers are already functioning in pulsed operation at room temperature and above, over a very broad spectral range (5-12 µm). Single frequency QC-DFB lasers are available. However, the maximum operating temperature for continuous wave operation is still ~ 150 K, imposing a strong technological limitation for all systems which require high frequency modulation and/or narrow line width. We propose to develop and fabricate QC lasers operating in continuous wave mode on thermoelectric cooling elements, which meet the requirements of compact systems and could become the essential device for a new technology based on mid-infrared radiation. The aim of the project is to exploit fully the technological potential of quantum cascade lasers and open the way to entirely new mid-infrared applications, conceivable only if implemented with high performance mid-ir semiconductor sources. Quantum cascade lasers, based on intraband transitions, form a new class of devices, which are revolutionizing the world of mid-infrared sources. To date, QC lasers are already functioning in pulsed operation at room temperature and above, over a very broad spectral range (5-12 µm). Single frequency QC-DFB lasers are available. However, the maximum operating temperature for continuous wave operation is still ~ 150 K, imposing a strong technological limitation for all systems which require high frequency modulati
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'From symptom relief to disease modifying allergy treatment with Glycan-Allergen Immunotherapy' to be submitted under Horizon 2020.

assistant: **Abstract**

The annual increase in prevalence of allergy related diseases develops at an alarming pace worldwide. Responsible disease mechanisms are characterised by unwanted immune responses to substances which do not harm healthy individuals. The allergy therapeutics market is now dominated by symptom alleviating antihistamines, decongestants and corticosteroids. The main patient need is to get cured with a disease modifying medicine instead of the chronic use of symptom relieving products. Allergen-specific Immunotherapy (AIT) attempts to treat the underlying cause by inducing allergen-specific immune tolerance. However, currently used AIT with high doses of extract is not effective enough (only 20% better than placebo), risks severe side effects and requires 5 years of treatment.DC4U is developing a new generation of disease modifying allergy treatment with the potential to replace symptom relieving products and current AIT. We apply a new and unique technology to present allergens to the immune system as being SELF and SAFE, using glycans as endogenous human protein recognition elements. Our lead product, “sia-GP”, is a grass pollen allergy treatment for life long protection, achieved in a short treatment course. DC4U has shown highly promising in-vivo dose-response efficacy results and will further develop this proprietary product up to and including Phase IIa clinical trials. This will be followed by out-licensing to a pharmaceutical company. Effective curative tolerance inducing therapy will contribute to global medical needs and reduction of healthcare costs.In this SME-1 we will elaborate and refine our clinical plans, IPR strategy, market analysis and profitability analysis. Furthermore, we will initialize discussions and negotiations with several possible investors and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'A EUROPEAN MULTI-DISCIPLINARY CLINICAL PROJECT MEANT TO IMPROVE THE MANAGEMENT OF PATIENTS WITH POOR PROGNOSTIC OVARIAN CANCER AFTER NEOADJUVANT CHEMOTHERAPY: RESTORING HOPE, SALVAGING LIVES', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

The standard medical-and-surgical treatment of ovarian carcinoma patients relies on a systemic chemotherapy (carboplatin-paclitaxel), a tumor debulking surgery meant to be complete (no post-operative residual lesion), and a subsequent maintenance treatment with modern targeted agents. Recent studies identified a patient population (~14,000 patients / year in Europe), whose prognostic is poor (5 year-overall survival (OS) <20%) due to a refractory cancer, characterized by a poor chemosensitivity (assessable online with the numeric CA-125 KELIMTM score <1.0), and by a disease found non-resectable disease after 3-4 cycles of chemotherapy. In these patients, there is a high uncertainty about the best treatment adjustments to apply. SALVOVAR is a European project led by HCL, meant 1) to raise the physician awareness, and propose practical and affordable diagnostic tools for identifying these patients, and 2) to assess the utility (OS benefit), acceptability (quality-of-life; patient perception) and affordability (cost-effectiveness, including country coverage policies) of solutions based on adjustments of their medical-and-surgical treatment. These solutions implementable in routine may improve their prognosis, according to recent literature data. The project will be based on a large pragmatic randomized phase III trial, sponsored by ARCAGY-GINECO group, and activated in 6 countries (ENGOT network; ~100 recruiting centers), with the objective of demonstrating an OS benefit with the chemotherapy densification (weekly carboplatine-paclitaxel dose-dense regimen) compared to the continuation of the standard 3-weekly regimen. Total 685 patients treated with the standard neo-adjuvant chemotherapy will be pre-screened to randomize 240 patients. Dissemination, and communication will