RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Analysis and assessment of the new European Agri-food Law in the contexts of food safety, sustainable development and international trade' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

In Europe, agri-food legislation has been substantially transformed between 2002 and 2007. The result is metamorphosed law that must take place at the same time in a global free market economy, in European policies of public health and sustainable development, and in the legal regulation of global trade. This metamorphosis rendered inevitable in order to respond to three essential concerns: Developing the economic sector based on a high level of food safety; Putting food law and the European strategy of sustainable development in phase; Transcribing into the new agri-food law the environmental, cultural or social values Europe wishes to defend within the international trade.   This new law is extremely fragmented and disparate, a fact that might hamper its understanding. This is why there is need to make it formally and substantially homogeneous in order to study it afterwards, to develop its study at universities, to make it more easily accessible to economic operators and to diffuse its contents to non European countries wishing to have their food products accepted in Europe.   This radical change in agri-food law has a particular importance since this law must take the perspective of sustainable development into account. So, it is necessary to determine the content of the sustainable development concept in relation to food legislation.   Such a determination will contribute to put in light the shared and non market-oriented values for which agri-food law is or should be a key contributor. Some of them have roots which may likely go back as far as when agriculture began. Others come from our social history, Human rights, actuality& Beyond the search for these values of our origins, past or present, the effort is to envisage concretely how the cultural relations of man
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Molybdenum, rhenium and osmium isotopes in banded iron formations as paleo-redox indicators for the ocean oxidation state in early proterozoic time.' in the context of a Fifth Framework call.

assistant: **Objectives**

Between 2300 to 1800 million years ago the Earth's oceans became toxic. Potential paleo-redox indicators will be identified in Proterozoic marine sediments, in order to study this important change that influenced climate and development of life on Earth.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Sustainable road arisings project', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

This proposal describes a novel technology for conversion of sub soil construction waste, and pulverised fuel ash (pea) into a non-plastic construction material. The reprocessed material will reduce the requirement for landfill dumping of both waste products and produce an alternative aggregate for use in road construction The recycling of these waste products will have a positive effect on the environment by removing the need for extra landfill sites, reducing the heavy freight traffic that is currently used to import and export the material and reduce the need for new aggregate quarry sources.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'HARMONISED APPROACH TO EARLY FEASIBILITY STUDIES FOR MEDICAL DEVICES IN THE EUROPEAN UNION' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

EU Regulations on medical devices (MDs), in-vitro diagnostics, and Health Technology Assessment envisage a harmonised lifecycle approach for clinical evidence generation of MDs. To be effective this approach requires evidence generation plan to be developed since early stages of product development, by engaging all relevant stakeholders.At present, in the EU there are no standardized procedural frameworks/guidelines/common reference standards for Early Feasibility Studies (EFS), clinical investigations allowed by ISO 14155:2020 conducted early in the development aiming to inform the product development.The ambition of the HEU-EFS project is to develop a harmonised framework for the EU EFS Program, as one integrated step of evidence generation cycle. Project objectives include: (1) conducting research/analysis on state of play (i.e., characteristics, challenges, impacts) of pre-market programs for MDs, including EFS; (2) building a sustainable network of stakeholders at EU/national level to promote/support EFS implementation; (3) developing a sound, widely applicable, harmonised EU methodology and formulating recommendations to uptake EFS; (4) undertaking pilots to test the proposed framework; (5) developing instruments to monitor the EFS performance; and (6) implementing a dedicated, sustainable, open access online portal dedicated to EFS methodological framework, best practices and network.To achieve these goals, the HEU-EFS consortium has been designed including a wide range of relevant stakeholders: research organisations, HTA bodies, patient organizations, healthcare providers, SMEs (including health technology developers, legal experts, and a CRO), and 6 major private companies that are part of a pre-identified industry consortium. An Advisory Board made of compete
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Data for Development: the implications of new types of digital data for international development'.

assistant: **Objectives**

The current exponential increase in the use of digital communication technologies in low and middle income countries has the potential to make their citizens a rich mine of information about health interventions, human mobility, conflict and violence, technology adoption, communication dynamics and financial behaviour. However, the default mode is currently for this to happen without their informed consent or involvement, and without ethical and normative frameworks to ensure data protection or to weigh the risks against the benefits. This proposed research will explore the implications of ‘data for development' – the use of new types of digital data, for example from mobile phone traces or social media activity, to shape  development interventions by governments and international institutions. The research is specifically concerned with how the availability of such data is drawing new actors and institutions into the field of international development; how development organisations are dealing with the ethics of privacy and data protection in this context, and how the potential benefits of knowing more about developing-country populations are being weighed against the risks of being able to track and identify individuals and groups. The research will take an ethnographic perspective focusing on three groups: the individuals producing the data, the organisations and institutions using it, and the policymakers and technology firms dealing with the technical and regulatory aspects of data production and storage. Through three case studies it will look at such issues as the framing of privacy in a developing-country context; models for participatory consent on the part of users; location-specific aspects of technology design and architectures, and the theoretical debates e
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Life is Science in a Digital World' (LiS-Dig) under Horizon Europe.

assistant: **Objectives**

For the third and fourth edition of “Life is Science” the Austrian Centre of Industrial Biotechnology plans to extend its thematic focus on life sciences to the topic of digitization and has initiated a cooperation with St. Pölten University of Applied Sciences. Together, an open event for the general public in the frame of the European Researchers’ Night is planned in Austria: Life is Science in a Digital World (LiS-Dig). Visitors will gain insights into the every-day work of researchers in the disciplines of life sciences and digitization and their impacts on our daily life. The event offers the participants to discover scientific contents along the following dedicated story lines: Health & Food, Climate & Environment, Culture & Community and Digital Transformation. Visiting laboratories and organizations, putting hands on, discussing with scientists, contributing to open innovation and citizen science and watching demonstrations, the participants will dive into recent scientific discoveries. The ""Researchers at School"" activities (workshops in school classes) will provide an increased flexibility for schools to attend the event independently from the main events in 2022 and 2023.The envisaged activities aim to allow visitors to identify the connection between research and our daily life. To drive participants’ motivation to be active at LiS-Dig, they will have the possibility to win some gifts (hotel vouchers, book vouchers, experimental kits etc). In this way, some may discover their passion for science and their preference for a research career.""


**Keywords:** Life sciences, open event, science communication, digitization
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Epigenetics and DNA repair. Is a chromatin remodeling process involved in the higher UV sensitivity of nucleotide excision repair defective cells?' (EPINER2007).

assistant: **Innovation**

The knowledge on regulatory roles of epigenetic mechanisms (heritable changes in the genome function without a change in the DNA sequence) has grown very fast during the last decade since they can be the target for treating several pathologies related to cancer and neurodegeneration. In the base of these diseases have also been found deficiencies in DNA repair mechanisms. In this respect, two human syndromes (Xeroderma Pigmentosum and Cockayne’s Syndrome) affecting one of the major DNA repair systems in human cells called nucleotide excision repair, characterized by sensitivity to UV irradiation, become an interesting model to contribute to unravel the link between chromatin remodeling processes and DNA repair. Expected results on the possible influence of chromatin remodeling processes to the higher sensitivity to UV radiation of Cockayne’s Syndrome cells will lead to perform further investigations to understand how these mechanisms are involved in the development of cancer and/or neurodegeneration found in these patients. Since the proposed investigation require a multidisciplinary study (cytogenetics, molecular biology and immunocytochemestry), it will become of the utmost importance not only for the research activity planned to carry out at the Laboratory of Prof. Palitti, since this line of research fits very well with the purposes already established by the Network of Excellence (NoE – Epigenetic Network created by several laboratories from Europe) supported by the FP6 program from the European Community; but also for having the possibility to incorporate new methodologies and strategies to continue with the study of possible links between epigenetic and DNA repair in our laboratory in Uruguay with the aim to initiate studies on epigenetic therapy mainly applied t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'Development of an innovative power network balancing concept for safe reliable and cost effective distribution of electricity'.

assistant: **Objectives**

The needs of electrical energy increase continually in Europe that's why we observe today the development of interconnection and energy exchanges between European networks. This trend leads energy providers to a uniformisation of voltage levels and to require a better quality of supply energy. They nowadays face problems dealing with voltage imbalances and more especially in low voltage distribution networks. Moreover, European Community aims at deregulating energy market. Thus energy quality will be more and more difficult to control. Therefore on 5 th July 1994, the European standard EN 60 150, Specifications for voltages supplied by public distribution networks, was adopted in all Europe. But today energy providers are not able to strictly apply the electricity quality standard and above all EN 60 150 standard. Networks remain unbalanced, they still affect customers' and industrial plants' appliances. In addition deregulation could increase the phenomenon and bring hazardous effects. The aim of this project is therefore to design and develop a safe, reliable and cost effective balancing system. Power electronics and artificial intelligency combination will allow to regulate unbalanced power. The concept is: 1. to identify unbalanced network 2. to catch under used energy from a line and bring it to overused other. 3. to maintain balanced network in normal working conditions. The system will address both energy providers and industries. This system will allow energy providers to make networks conform to the European standard EN 60 150 and so to supply better quality of electricity. With the balancing system, customers will use the complete power supply for which they pay and appliances will no more be damaged by unbalanced networks. The balancing system concerns also a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Community programme of research on environmental hormones and endocrine dirupters' (1994-1998), addressing dissemination and exploitation.

assistant: **Impact**

The development by man of an increasing array of new chemicals and their inevitable release into the environment poses a major threat to ecosystem health. This is particularly true of the aquatic environment, which receives direct discharges of industrial and domestic waste waters as part of man's normal waste disposal system. Recent evidence shows that some of these chemical and effluents can affect wildlife at concentrations much lower than their measured acute toxicity range by specifically interfering with the endocrine system. This can occur by a variety of mechanisms which include mimicry of natural hormones (agonism), blocking hormone receptors (antagonism) and interference with hormone synthesis or metabolism. Evidence of effects at the level of individual organism suggest that these phenomena may be widespread in the aquatic environment but demonstrations of impacts at the level of population, community or ecosystem are rare. Thus, our present state of knowledge implies that endocrine disruption of wildlife may be a widespread and potentially serious environmental problem which will require future management but our knowledge of its true extent and severity is very limited. COMPREHEND is a programme of research to assess the extent of the problem on a Europe-wide basis, to identify the principle components of waste water effluents responsible for endocrine disruption, to search for hard evidence of impacts at the population level and to develop new tools for the early warning of endocrine disrupting activity in effluents and chemicals. It concentrates on the impacts on sexual reproduction in aquatic animals (freshwater, estuarine and coastal) with particular, but not exclusive, reference to fish because the consortium of scientists involved believe that this is
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Mutant p53 gain of function activities as determinants for tumor prognosis and therapy' (1998-2002) targeting Fifth Framework.

assistant: **Abstract**

P53 gene mutations are common in cancer. Human tumors accumulate abundant mutant p53 protein. Wild type (wt) p53 is a potent tumor supressor. In addition to loosing the inhibitory functions of wt p53, cancer-associated mutant p53 may gain new oncogenic functions to actively promote cancer. Wt p53 is studied extensively, but little is known about gain of function of mutant p53 and its relevance to cancer. Based on recent findings by the partners, we will explore biological effects of tumor-derived p53 mutants and their biochemical basis. We will use cell-free assays, cultured cells and mouse models. Different mutants will be compared. A special database will address correlations between mutant p53 status and patient outcome. Using a novel assay, chemical libraries will be screened for p53-inhibitory drugs. This should advance understanding of cancer etiology and define new therapy taegets.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'SECURITY HARMONIZED INNOVATION FOR ENHANCED LAW ENFORCEMENT CAPABILITIES IN DYNAMIC CROWD PROTECTION THROUGH PRE-COMMERCIAL PROCUREMENT'.

assistant: **Concept**

The SHIELD PCP initiative aims to drive innovation by empowering buyers to actively influence the development of cost-effective solutions tailored to their unique requirements. The overarching aim is to equip security stakeholders with cutting-edge technology procured through innovative processes, offering solutions that enable seamless coordination and cooperation among all stakeholders, especially law enforcement agencies (LEAs).Building on the achievements of its predecessor, SHIEL4CROWD, the SHIELD PCP project adopts a top-down approach. This method consolidates widely agreed-upon scenarios to address critical security challenges, providing a detailed identification of innovation needs at both the process and technology levels. This top-down approach enabled the alignment of stakeholders, from security forces to public authorities, ensuring innovative solutions meet shared needs for public space protection. SHIELD4CROWD also developed a roadmap of innovations addressing operational and technical challenges while considering regulatory and economic factors. SHIELD PCP continues this work to enhance collaboration and improve public space security.The project follows a phased Pre-Commercial Procurement (PCP) process, which includes: Preparatory Phase: Finalizing the tendering documentation developed during SHIEL4CROWD; Phase 1: Solution Design ;Phase 2: Prototype Development; and Phase 3: Operational Validation, conducted across three pilot sites in France, Spain, and Slovakia.A consortium of 10 partners from 6 EU countries, including 3 Ministries of Interior and 1 public transport operators as Public Buyers and 1 end-user, is collaborating on this project. Many other end-users will also be involved through the User Observatory Group (UOG).


**Keywords:** Coordination