RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'PortPath: A Portable Device for Detecting Pathogens' under Horizon 2020.

assistant: **Concept**

Many of today’s water resources are contaminated by pathogenic bacteria, which cause serious diseases, especially in low-income countries. One particularly grave concern is Vibrio cholerae, the disease-causing agent of cholera, with an estimated 1.3 to 4.0 million cases worldwide every year and an estimated annual mortality rate of up to 143,000 people. The current state-of-the-art detection methods for this pathogen have high demands on the equipment and on the expertise of the investigating person. In addition, a positive detection generally takes several hours and is very expensive. PortPath presents a completely new approach for the detection of pathogens (with emphasis on the cholera pathogen), which is based on automated analysis of water samples contaminated with pathogens. PortPath is not only much faster and cheaper than previous detection methods but can also be used by non-medical laypersons. An easy-to-use software together with low-cost hardware shows whether pathogens are present in a water sample. The software uses the recent developments in computer technology, especially in machine learning strategies. Significant components of PortPath have already been developed. The two objectives during the Proof of Concept phase are (1) the technical validation with a first prototype of PortPath, and (2) the development of a business plan for PortPath.


**Keywords:** pathogen, detection, tracking, motility, microbe, water, app, smartphone, magnification, algorithm, health, machine learning
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Intergenerational Reproduction and Solidarity in an Era of Family Complexity' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

One of the important consequences of the Second Demographic Transition has been the increasing complexity of families. The aim of this project is to study how rising family complexity has affected two fundamental aspects of intergenerational relationships: reproduction and solidarity. Theoretically, family complexity is distinguished into four dimensions: (a) the length, timing and nature of exposure to the child, (c) biological relatedness to the child, and (c) characteristics of parent-parent ties (triadic effects), (d) characteristics of the wider family network. Using insights from several disciplines, I develop a common theoretical framework for understanding intergenerational reproduction and solidarity. To test the theory, an innovative multiactor survey is developed with an oversampling strategy in which for each adult child, information is collected on all parent figures, and for each parent, information on all adult children. In addition, register data are used to analyze one aspect of reproduction in a dynamic fashion (educational reproduction) and vignette data are used to analyze one aspect of solidarity in more depth (norms prescribing solidarity). By studying reproduction and solidarity as outcomes, I shift the traditional focus from examining how the SDT has affected individual well-being, to the question of how the SDT has affected relationships. In doing so, I analyze a new problem in demography and sociology and contribute to classic debates about population ageing and social inequality. Theoretically, the study of family complexity yields unique opportunities to test ideas about the nature of intergenerational relationships and will shed new light on the traditional dichotomy of social vis-à-vis biological bases of intergenerational relationships. Me
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Next Generation Wireless Broadband Access Systems and Advanced Coding Techniques'.

assistant: **Objectives**

The scientific and technological objectives of this SME-driven industry-academia multi-disciplinary proposal for Intra-European Fellowship (termed Wi-CODING) are to provide the means for transfer of knowledge from the Host organisation to the Fellow with the aim of “strengthening a leading independent position in education or enterprise” in the future endeavors of the Fellow. The project aims to implement this plan within the context of R&D efforts aimed at making significant advances in key technology areas relating to the next generation broadband wireless access (BWA) systems and linked to the specific end-user requirements as specified in the emerging IEEE 802.16m (WiMAX) standard. Wi-CODING plan is consistent with the professional expertise and future plans of the Fellow. From Fellow’s point of view, it is expected that practical knowledge gained during the Project will provide him with ammunition for taking leading roles in projects of similar nature and complexity after returning to the home country. This will create a unique opportunity for professional career development and widening Fellow’s activities into the area of practical implementation of BWA systems. From the Host Organisation’s point of view, a near-term impact of Wi-CODING will be the incorporation of the project research results into BWA products currently being developed by the Company. In a broader context, the solutions will help to cement Company’s leading role as a provider of BWA solutions, enhance IPR portfolio and create a foundation for future growth and expansion. As the implementation plan for the project is based upon the next generation of the WiMAX system, Wi-CODING envisages close interaction with IEEE802.16m standardisation activities, aiming to influence the emerging standard. The
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Advanced study course water resources management in arid and semiarid regions using advance earth observation and gis techniques""' to be submitted under Fifth Framework.

assistant: **Abstract**

Many R&D projects are being carried out worldwide and within the European Union on the long-term stability of vitrified nuclear waste.The objectives of this topical workshop are to(1) discuss the actual status of the understanding of the behaviour of nuclear waste glasses in their anticipated disposal environment,(2) reach a consensus on the issues proposed in the workshop, and(3) improve the focus of the future projects on nuclear waste glass. A topical workshop bringing together the international experts is an excellent approach for achieving these objectives. The results of the workshop should be an enhanced consensus, a better focus in future programmes, and Proceedings with all oral papers and poster presentations.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Multi-Potent Polymer Precursor approach for novel conjugated polymers'.

assistant: **Innovation**

In this proposal, I introduce a new approach for the synthesis of conjugated polymers comprising anthraquinone and anthracene units in the molecular backbone and their use in ultra-thin film organic electronics. The preparation of these materials is possible via a common multi-potent precursor polymer obtained easily from anthraquinone via nucleophilic attack of an acetylide on the 9,10 position (yielding in a propargyl alcohol fragment) and subsequent polymerization via classic aromatic polymerization routes. Such precursor – whose chemical and processability properties can be tuned by modification of the propargyl alcohol moiety – yields both the final fully-conjugated anthraquinone and anthracene polymers by loss of acetylene or reduction respectively. In this way it is possible to overcome the limitation often fund in the synthesis of high-molecular weight fully-conjugated polymers. Moreover, one can introduce responsive functionalities to trigger the last step using diverse chemical, thermal, and photo stimuli, therefore allowing the realization of fine patterns and architectures via ink-printing, laser writing, and lithographic approaches. I propose to apply this methodology for the realization of ultra-thin inherently-conformable organic electronics devices that can find use in sensing, healthcare, and as electrode materials. Thanks to the orthogonality of the transformations introduced above, the approach described herein allows the preparation of up to three different phases from a single processable material, thus increasing the level of complexity achievable in thin-layer devices.


**Keywords:** Conjugated polymers, Precursor chemistry, Organic electronics, Organic semiconductors, Thin-layer devices,  Responsive materials, Anthraquinone, Acenes
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Strengthen IUNG’s proficiency on “Managing the Production of Food and feedstuff, their safety and quality under global Climatic Change”' (PROFICIENCY).

assistant: **Innovation**

The Institute of Soil Science and Plant Cultivation (IUNG) is a brilliant Polish Research Institute. ProFiCiency aims at strengthening IUNG’s excellence, through technological, human and partnership capacities fostering, and most of all through a complete reshaping of its internal organisation. IUNG ambitions to adopt a totally integrated interdisciplinary approach around four interdisciplinary priority research areas (Soil Quality; Land Use; Production Systems and Techniques; and Plant Products Quality and Safety) to converge towards excellence on a crucial topic: “Managing the Production of Food and feedstuff, their safety and quality under global Climatic Change”. This ambition is the red line of the whole Action Plan, derived from the SWOT analysis. Measurables objectives are the acquisition of 17 pieces of equipment; the reorganisation of laboratories, a new HR policy, the hiring of 5 experienced researchers, intense mobility trainings (56 outgoing, 30 incoming), a sustainable agriculture platform, 2 international conferences, 8 workshops, 3 trainings, 1 open day and 2 farmers days, 1 website, 8 newsletters. The ProFiCienCy project will rely on 16 partners all across the EU. It has raised wide support reactions from official bodies (Polish Ministry of Agriculture, Agricultural Chamber of Lublin, Foundation for Polish Science, Regional Agrochemical Stations, Association of Tobacco Growers, National Council of Individual Farmers Union “Solidarity”). The main expected project outcomes are a better penetration within the ERA and IUNG’s recognition as the most promising research centre in Poland on the interaction between climate changes and the production of food and feedstuff of quality and high safety. ProFiCienCy also corresponds to a complementary funding of IUNG f
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Optogenetic investigation of GABAergic interneurons in the limbic system during reward and addiction', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Many psychiatric disorders involve dysfunction of the limbic system that is manifested in a reduced ability to experience pleasure and learning and memory impairment.Dopamine is important in the limbic system, which includes structures such as the nucleus accumbens, ventral tegmental area and prefrontal cortex. Drugs such as opiates and cocaine, but also antidepressant agents, and deep brain stimulation can possibly recruit certain types of interneurons, whose function is to regulate the firing and integration of information in local circuits. Functional study of local inhibitory interneurons of two classes, parvalbumin and somatostatin interneurons, using optogenetics and mouse genetics are the main focus of this proposal. It is of great interest to better understand the function of distinct neuronal classes during reward-related behaviors, and to identify how dopamine neurtransmission in specific neuronal classes regulate behavior. I propose to apply optogenetics to study the functional impact of GABAergic interneurons during reward-related behaviors.  Functional studies of the limbic system have previously been limited to pharmacological approaches or lesion studies that provide poor cell-type specificity and low temporal resolution. Expression and control of light-activated channels using genetic methods in mice allows us to dissect the function of each neuronal class during awake behavior with millisecond resolution. The proposed research can provide important information on the function of discrete neuronal classes and their specific receptors, thereby providing the foundation for rational design of novel therapeutics targeting the limbic system.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Functional in vivo analysis of cholangiocarcinoma development, progression and metastasis.' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Genetic heterogeneity and complexity are hallmarks of metastatic solid tumors and therapy resistance inevitably develops upon treatment with cytotoxic drugs or molecular targeted therapies. Cholangiocarcinoma (CCC, or bile duct cancer) represents the second most frequent primary liver tumor and has emerged as a health problem with sharply increasing incidence rates, in particular of intrahepatic CCC (ICC). The reason for increased CCC incidence remains unclear, but influences of western lifestyle and a resulting altered hepatic metabolism have been discussed. Surgical resection represents the only curative option for the treatment of CCC, however, many tumors are irresectable at the time of diagnosis. CCC represents a highly aggressive and metastatic tumor type and currently no effective systemic therapy regimen exists. The overall molecular mechanisms driving CCC formation and progression remain poorly characterized and it thus becomes clear that a detailed molecular characterization of cholangiocarcinogenesis and the identification of robust therapeutic targets for CCC treatment are urgently needed. Taking advantage of our strong expertises in chimaeric (mosaic) liver cancer mouse models and stable in vivo shRNA technology, we here propose a comprehensive and innovative approach to i) dissect molecular mechanisms of cholangiocarcinogenesis, with a particular emphasis on Kras driven ICC development from adult hepatocytes and oncogenomic profiling of ICC metastasis, ii) to employ direct in vivo shRNA screening to functionally identify new therapeutic targets for CCC treatment and iii) to characterize the role of the gut microbiome for CCC progression and metastasis. We envision this ERC-funded project will yield important new insights into the molecular mechanisms of CC
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'European Management Platform for Emerging and Re-emerging Infectious disease Entities' (EMPERIE).

assistant: **Concept**

The EMPERIE (European Management Platform for Emerging and Re-emerging Infectious disease Entities) consortium has its roots in the lessons learned by the majority of the participating centres during the recent SARS and HPAI H5N1 outbreaks. The mission of EMPERIE is “to contribute to effectively countering the potential public health threat caused by new and emerging infectious diseases in Europe by establishing a powerful network capable of structural and systematic prediction, identification, modelling and surveillance of infectious diseases health threats and pathogens”. In pursuit of this mission EMPERIE will establish a network of centres of excellence combining the expertise, techniques and resources necessary for effectively countering (re)-emerging infectious diseases. We will establish common processes, procedures and communication channels in the network linked to relevant stakeholder organisations and local “grass root”” sites to contribute to a structural and systematic prediction, identification, modelling and surveillance of (re-)emerging infectious disease health threats and pathogens. Our focus will be new zoonotic viruses that may cause epidemics and viruses already present – but yet unrecognised- in humans. Within this focus, we will attain proof of principle of the functioning of the network and the techniques, systems, procedures and resources in the following RNA viruses: Flaviviruses (e.g. Dengue, West-Nile virus), Alphaviruses (e.g. Chikungunya), Orthomyxoviruses (e.g. Influenza), Paramyxoviruses (e.g Henipah,) Coronaviruses, Bunyaviruses ( e.g. hantavirus) and Filoviruses
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Sensor-based control of mobile robotic manipulators' (1994-1998) targeting Fourth Framework.

assistant: **Abstract**

Research objectives and content Mobile manipulators are robotic systems where manipulator arms are mounted on mobile robotic platforms, thus increasing the workspace of the arm, while, on the same time, endowing the mobile robot with the ability to interact with its environment by tools or sensors mounted on the arm. Systems of this type, which are subject to nonholonomic motion constraints like the ones occuring in many wheeled mobile robots, are of particular interest for practical applications. The presence of these motion constraints makes some promising sensor-based control schemes, like visual servoing, difficult to apply in systems of this type. However, a nonholonomic visual servoing framework has been recently proposed, the initial development which, is limited to the case of a one degree-of-freedom (d.o.f.) arm and to positioning and stabilization of the system with respect to a static target. We propose to study extensions to multi-d.o.f. arms and to moving targets, as well as related robustness issues, in order to make this method appea- ling to applications in e.g. industrial flexible manufacturing systems. It is expected that the first eight months of the project will be devoted to the theoretical part of this work and to relevant simulation studies, while the last four months will be devoted to its experimental evaluation. Training content (objectie, benefit and expected impact) Training objectives include further familiarization with research on the nonlinear stabilization problem, on homogeneous approximations of nonlinear systems and on robust nonlinear control techniques, with computer vision research related to non-metric and qualitative vision, as well as with tools and techniques relevant to real-time implementations of the above. These skills are
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Development of a mobile laser prototype (based on Raman back scattering technology) to measure precisely on natural sites and in real time, atmospheric pollution to contribute in elaborating tests and procedures for an appliable definition' (1994-1998).

assistant: **Concept**

The main goal of this project is to respond to the need of an efficient mean to measure the real degree of atmospheric pollution with high precision (positioning, date and gas concentration) and directly on site in order to inform and protect populations and to apply and generate applianccs to thc legal European rules. The here after High Tech SMEs are specialised in complementary technologies permitting to develop an ergonomic and efficient prototype of a mobile system to reach this goal. SOPRA is a French SME specialised in laser and QUANTA SYSTEM is an Italian SME specialised in time resolved analyser systems. They have imagine that crossing their know how they could undertake such a project based on a technology using the scientific rules known under the name of RAMAN back scattering". Considering both economical and technological aspects developing such a prototype is too much complicate and risky without the contribution of a major RTD. This searched RTD should have a good background on questions of atmospheric survey and on laser and spectrography technologies, he must be able to contribute in creating specifications and tests of the prototype and will write and discuss the appliable norms, needed in Europe on this matter. "