RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Biomechanics of the dromaeosauridae' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

Research objectives and content The Dromaeosauridae, known largely from North America and Mongolia, were small- and medium-sized dinosaurs, characterised by slender long limbs, elongate stiffened tail, and a substantial slashing claw. Birds probably arose from Dromaeosauridae, but their relationships to other dinosaurs are disputed. In addition, modes of life are debated: scenarios include active pack hunting and balancing on one leg while slashing with the other. This project will focus on anatomical and biomechanical aspects of dromaeosaurids. We have access to a superb new dromaeosaurid specimen from Italy, nearly complete and including preserved soft parts. We have also negotiated access to North American and Mongolian specimens. The project will involve innovative techniques of anatomical analysis, biological and chemical study of soft parts, computerised phylogenetic analysis, and simple biomechanical modelling, to test dromaeosaurid skeletons for bone strength, running speeds and styles, balance and slashing, and other aspects of locomotion. Training content (objective, benefit and expected impact) The project will extend my knowledge of dinosaur anatomy, systematics and biomechanics. New computing skills will be acquired. This will provide a training for a variety of research and applied scientific careers in systematic biology, palaeobiology, or computing. Links with industry / industrial relevance (22) The computer work in systematics and biomechanics may lead to software developments of interest to other researchers in academia and in industry.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'A Collaborative platform for EU-US NGI experiments' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

NGIAtlantic.eu, in its 38 months rigorous workplan, has a central goal to provide the organisational and financial framework that will drive the cascade funding of the EU-based research and innovators in carrying out Next Generation Internet (NGI) related experiments built on top of EU – US experimental platforms. NGIAtlantic.eu develops, manages and publicises to targeted user communities an organisational and financial funding platform to stimulate and support an efficient process for regular research cycles of cascade funded projects engagements between EU and US innovators related to common priority topics derived from the EU’s NGI related Experimental Platforms, including NGI Experimentation (NGI-EXP), FIRE, 5G-PPP, and the US’s relevant Internet programmes, including the NSF’s wired funded programs, ENTeR / GENI and Future Cloud Platform, and Platforms for Advanced Wireless Research (PAWR) program and dedicated US-EU program entitled Internet Core & Edge Technologies, ICE-T. The funded projects will emerge from clearly established selection criteria, through a transparent and efficient process of 50+ External Pool of Evaluators.The Partners from both EU & US, have been selected to bring the necessary competences in all crucial areas required by the call, from technical knowledge, direct experience in EU-US collaborations, cascading grant management expertise, to NGI policy understanding and experience in experimental platforms in EU and US, and with experience in mobilising the expected communities of users to make trans-Atlantic collaboration a success from all viewpoints. The Consortium is supported by an Expert Advisory Group (EAG). Main Project outputs: 1 platform & open call processes, Twinning lab, 30+ EU-US NGI experiments, 50+ EU & US organisations receivi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Shaping Innovative Designs for Sustainable Tissue Engineering Products', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Shaping Innovative Products for Sustainable Tissue Engineering Strategies - SHIFT is the follow up of MSCA-RISE REMIX (GA 778078). While REMIX researched and confirmed the potential of natural origin material such as silk proteins, collagen, keratin and marine organism-derived polymers for use in Tissue Engineering and Regenerative Medicine, SHIFT aims to take the research a step forward and design innovative natural-based, scalable constructs that enhance angiogenesis for the treatment of widespread chronic pathologies, such as large defect in bone and cartilage and the treatment of chronic wounds (ex. diabetic ulcer). Prototypes will be fabricated considering scalability, costs, regulatory issues.Multiple strategies will be used to achieve this aim:- pre-assessment of the regulative framework for TERM products and close collaboration with the industry; - fabrication in accordance with current GMP and ISO quality management Systems-requirements- standardization of  the protocols for  purification of raw materials from the waste of textile and food industry for the production of these prototypes, using medical-grade, commercially-available raw materials as benchmark. This may lead to the opening of a new opportunity for re-using industrial waste which is currently disposed of.- application of the principles of Green Chemistry to reduce the environmental impact of the research and production of the prototypes. An extensive training program will be offered to ESRs to set the best conditions for successful performance. The program will be offered through summer schools and online seminars and will cover a variety of topics related to TERM, technologies, regulations for product development. A special highlight will be devoted to product-development, spin-off, venture capita
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'What are the origins of empathy? A comparative developmental investigation' (EMPORIGIN), addressing dissemination and exploitation.

assistant: **Impact**

Empathy – sharing and understanding others’ emotions and thoughts – is a defining feature of what it means to be human. However, we lack knowledge about the origins of empathy and to what extent its sub-components reflect species and cultural universals. Studying infants and great apes enables us to identify the developmental and evolutionary origins of empathy and the extent of its human uniqueness. Until now, it has largely been assumed that infants and great apes lack the capacity for empathy. However, this claim may reflect a lack of adequate methodologies and research attention, leaving infant and great ape empathy underestimated. Now, combining novel techniques to investigate empathy comparatively (thermal-imaging, pupillometry and eye-tracking) with longitudinal observations and innovative experiments, EMPORIGIN will overcome this issue to provide the first comparative investigation of empathy development in humans and bonobos, our closest living relatives. Rich datasets on bonobo (wild and semi-captive) infant development and caregiver interactions will be compared to those from human infants in two small-scale, traditional societies – Vanuatu and Samoa. Both societies show distributed-caregiving but vary in societal structure and emotional expressivity. Using a cross-species and cross-cultural approach, EMPORIGIN will deliver step-change insights into empathy development that go far beyond the State-of-the-Art. We will test the hypothesis that humans and bonobos share a core capacity for empathy, but humans diverge in a greater motivation to ameliorate others’ emotional states and a capacity for reciprocal emotional exchange. These capacities could lead to a cascade of human-unique forms of sharing and co-operation. Combining approaches across biology, psycholo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fourth Framework proposal on 'The role of HLA genes in the development of chronic immunological disorders such as coeliac disease'.

assistant: **Innovation**

Objectives: Aims of the project: To use coeliac disease as a model for understanding the molecular basis of HLA association in disease. The main objectives are a) to elucidate, at a molecular level, the link between the HLA-DQ2 association and the immunopathological response to gliadin and b) to use this knowledge to investigate new treatment strategiesBackground: HLA molecules are central to the function of the immune system. By presenting fragments of foreign and selfproteins to T cells, they regulate the immune responses of the body. The pivotal role of HLA in biomedical research has been underscored by the awarding of two separate Nobel prizes for research on HLA. The development of several chronic immunological disorders including insulin dependent diabetes mellitus, rheumatoid arthritis and coeliac disease depends both upon environmental and genetic factors. In these so-called HLA associated diseases, HLA genes are major genetic components. The rational design of effective prevention and therapy of HLA associated diseases requires a molecular understanding of how HLA molecules are involved in their pathogenesis. For many diseases this understanding is hampered by poorly defined HLA associations and unknown disease eliciting antigens. In this respect coeliac disease, an inflammatory mucosal disease, is an extraordinary exception. The HLA association (HLA-DQ2) is well defined and the disease eliciting antigen (wheat gliadin and related cereal proteins) has been identified.In addition, HLA-DQ2 restricted, gliadin specific T cells have been isolated from the disease lesion of the gut, suggesting that these T cells playa role in the development of the disease. The actual gliadin derived peptides recognised by these T cells, however, still remain to be identified. Aims
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'International scientific conference on research on patient safety' demonstrating excellence, impact and implementation quality for a Sixth Framework call.

assistant: **Abstract**

The Luxembourg and UK Council of Ministers Presidencies in 2005 created a consensus for action in Europe on patient safety. National ministries of health are engaged through the European Commission-coordinated High Level Group on Health Services and Medic al Care. The World Alliance for Patient Safety, established by the World Health Organisation, brings together a wide range of stakeholders, including patient organisations, professionals and industry as well as public bodies. We propose a conference, PATIENT SAFETY: Research into Practice, to be a focal point for promoting and disseminating research and international action, strengthening broad-based initiatives and proposing evidence-based standards for practice. The conference will be led by the UK Faculty of Public Health and University College London, working with the World Alliance for Patient Safety.In the setting-up period, the conference parameters, its timing and place, expected numbers and broad themes, will be confirmed. There will be a Call for Papers, to be presented in parallel sessions, a high-quality plenary programme and an active communications strategy to international media. Outputs will include discussion of new measurement methods, instruments and research designs, and exchange of experience on patient safety research between international organisations and dissemination of new approaches. Furthermore, the conference will provide a unique opportunity to build upon the current work of the WHO in setting global research priorities, with the adaptation of research priorities to the European context.PATIENT SAFETY: Research in to Practice will serve the international agenda of the World Alliance, the agenda of EU member and associated states, and the interests of OECD and the Council of Europe. The co
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Settlement and Landscape Organisation of the Persepolis Region' (SELOPerse).

assistant: **Innovation**

The SELOPerse project aims to study the ancient Achaemenid occupation in the vicinity of the prestigious Unesco’s classified site of Persepolis (Iran, Fars province), one of the sumptuous royal residences built by King Darius I (520-486 BC). The project based on a new vision of the site organisation scheme as a kind of “garden city”. It means widespread settlement blocks ensuring the administrative and economic functions of what it was a provincial capital and sheltering the numerous inhabitants. The buildings blocks were probably located within a landscaped area of gardens, parks, fields and orchards. Farther in the wide and fertile Persepolis plain the exploitation of the natural resources and cultivation were managed by a network of local administrative centre and farms.Due to the present day human pressure and intensive cultivation the remains of the Achaemenid landscape disappear gradually. Traces of ancient settlements or infrastructures are difficult to find. The only way to study the still preserved remains is to carry out large scale studies by combining multiple survey methods (field walking and geophysical surveys) and excavations on selected points. The multidisciplinary and multiscale approaches will allow to rescue the archaeological information and to demonstrate our renewed hypothesis.The SELOPerse project will be host by the Ravenna department of heritage studies of the University of Bologna (Italy), centre of excellence in archaeology. It will be supervised by Prf. P. Callieri, the Italian co-director of the Iranian Italian excavation and restoration project in Persepolis carried out by a collaborative team. Involved in this multidisciplinary team, I will manage and carry the surveys. As underline by this existed project of the University of Bologna, a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Determinants of Alternative Food Networks and Exchanges' (DAFNE) targeting Seventh Framework.

assistant: **Abstract**

Changing consumers' and producers habits and preferences in favor of more sustainable-oriented foods can be (socially and privately) complex and costly. New institutional economics explain these dynamics by analyzing the choice of the “most cost-economizing” governance structure to carry out a transaction where credence attributes are involved. Consumption habits and/or production techniques for credence foods are adopted (as any other investment decisions) when a governance structure can ensure the minimization of the (production and transaction) costs associated with this change. The way different institutional settings or governance structures can influence the change of consumers and producers perceptions and preferences for credence foods is completely neglected. On the other hand behavioral economics underlines the role of  status quo bias and framing in this type of decision making process. We use new institutional and behavioural economics arguments to conceptualize the emerging of a new governance structure in the domain of credence food transactions which we defined as food community network (FCN) .
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Cytochrome c biogenesis in higher plant mitochondria' demonstrating excellence, impact and implementation quality for a Sixth Framework call.

assistant: **Abstract**

Abstract: The research program aims at studying a mechanism specific of land plant mitochondria: the biogenesis of c type cytochromes. This mechanism taking place in the mitochondria inter membrane space is performed by a multi-submits protein complex composed of subunits encoded in both the nuclear and the mitochondria genome. The first goal of the research will be to purify this complex and to characterise its subunits. This project also fits in the wider problematic of gene expression coordination between the nucleus and mitochondria. This study was initiated during the post-doctoral training course financed by a Marie Curie fellowship. The particular case of the cytochrome assembly complex and its relation with the rest of the plant cell will preferentially be used as a model during this study. The study of cytochrome c biogenesis is also very interesting in the context of the recent discovery of the involvement of cytochrome c in the triggering of programmed cell death (PCD). It is possible that this metabolism could act as a regulator in some PCD mechanisms involving cytochrome c. DNAmicroarray technology will be used to investigate the expression regulations of cytochrome c biogenesis genes and the relations of this mechanism with other mechanisms in the plant cell, particularly PCD. This research project, with its purpose of answering precise biological questions, will use biochemicals well as genetic techniques. It will also allow the implementation and adaptation of advanced technologies in the laboratory of origin, in particular polemics and DNA micro arrays, to the research field of plant mitochondria.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Nitrous acid and its influence on the oxidation capacity of the atmosphere' (NITROCAT) targeting Fifth Framework.

assistant: **Abstract**

Problems to be solved:It is presently accepted that nitrous acid (HONO) plays an important role for the oxidation capacity of the atmosphere. In addition, HONO is an important indoor pollutant, which can react with amines leading to carcinogenic nitrosamines. However, many questions concerning the formation and degradation of this trace gas in the atmosphere are still poorly understood. Problems to be solved by the consortium address the following questions:1. What are the weights of the various HONO formation pathways in urban, rural and polar regions of the troposphere;2. In particular, is the aerosol surface (soot, secondary organic, aqueous aerosol, cloud droplets) an important HONO source or is HONO formed only on the ground;3. What is the quantitative relevance of HONO photolysis to the OH budget and consequently to the oxidation capacity of the atmosphere?Scientific objectives and approach:Significant progress towards answering these questions can only result from an integrated research project which combines field, laboratory and modelling studies. The field studies primarily focus on the formation of HONO in urban areas and take into account transport phenomena. HONO daytime formation rates are determined to clarify the importance of HONO photolysis to the oxidation capacity of the atmosphere not only at sunrise but also at noon. In addition, the vertical gradient of HONO is measured to differentiate between HONO formation on aerosols and on the ground. Finally, HONO is also measured in polar regions to provide a database, which can be used to validate the assumption that the oxidation capacity in the polar region is controlled by HONO photolysis. In the laboratory studies kinetic and mechanistic investigations of the relevant heterogeneous reactions leading to
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'A Novel Biomimetic Bone-like Material' (BONEMIM) under Seventh Framework.

assistant: **Objectives**

Conventional orthopedic implants and dental filling approaches are only partly successful in preventing load-bearing failures and long-term durability, respectively. The problem in the current materials for bone repair and regeneration is that none of them has the hierarchical structure of natural bone that incorporates inorganic crystals with organic molecules. Any long-lasting biomimetic bone-like material should be designed from a well-dispersed inorganic nanoparticle phase in an organic matrix. This work is going to accomplish the following objectives: 1) Development of organic/apatite hybrid biomaterials based on apatite nanoparticles dispersed in a polymer gel. 2) Determination of physicochemical factors affecting the self-assembly of the hybrid material. 3) Characterization of micro- and nano-structure of the hybrid material. 4) Evaluation of mechanical strength and interfacial characteristics of the self-assembled biomaterial.  Micro-/nano-structural characterization of this new biohybrid material will be done by using several techniques to investigate material composition and morphology. The mechanical properties of the designed biomaterial will be tested. The outcomes of this research will provide a novel approach for bone regeneration and will serve as a basis for future in-vivo experiments with the long-term goal of repairing bone defects.