RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Inter- and Intra-Individual Differences in Knowledge-Based Inference Generation During Reading Comprehension: The Role of Working Memory Capacity and Utilization'.

assistant: **Concept**

Reading comprehension is a high-order complex process that depends on the operation of various cognitive mechanisms. The present research aims to explore the interaction of three central mechanisms: knowledge-based inferences, working memory (WM), and motivation. Specifically, the proposed research was designed to study the involvement of the different functions of working memory—storage, processing, and control—in inference generation via different forms of text processing (text maintenance, text reactivation, and text suppression, respectively). A comprehensive interdisciplinary approach is adopted to explore the extent to which these comprehension processes underlie inter-individual and intra-individual differences. Specifically, by using cognitive-behavioral techniques (e.g., probing procedures), eye-tracking methodology, and computational modeling, I intend to study the extent that each of the target processes (a) explains different types of reading disabilities, (b) typically develops with age, and (c) is modulated by reading comprehension motivation. The theoretical contribution of the present investigations to the cognitive models of reading comprehension and the practical implications on the development of comprehension strategies and remedial programs are stressed throughout the proposal.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Development of innovative lightweight and highly insulating energy efficient components and associated enabling materials for cost-effective retrofitting and new construction of curtain wall facades' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

We will validate an affordable (28% reduction of total costs) and lightweight (35% weight reduction) solution for envelope insulation to bring existing curtain wall buildings to “nearly zero energy” standards while complying with the structural limits of the original building structure and national building codes. Two key commercial insulating products:• Highly insulating mono-component and environmentally friendly spray foam, EENSULATE foam, for the cost-effective automated manufacturing and insulation of the opaque components of curtain walls as well as for the significant reduction of thermal bridges during installation (SELENA and EVONIK in cooperation with ULSTER);• Lightweight and thin double pane vacuum glass, EENSULATE glass, for the insulation of the transparent component of curtain walls, manufactured through an innovative low temperature process using polymeric flexible adhesives and distributed getter technology, thus allowing to use both annealed and tempered glass as well as low emissivity coatings (AGC, SAES and TVITEC in cooperation with ULSTER and UNIVPM ). A multi-functional thermo-tunable coating will allow for dynamic solar gain control as well as anti-fogging and self-cleaning properties (AGC in cooperation with UCL).They will enable insulating solutions that Focchi, DAPP and Unstudio will promote with two different levels of performance:• EENSULATE Basic curtain wall modules where the thermal and acoustic insulation will be provided by the novel EENSULATE glass and EENSULATE foam in the spandrel combined with state of the art low-e coated glass;• EENSULATE Premium modules integrating the thermo-chromic coated glass with additional self-cleaning and anti-fogging functionalities. BGTEC will exploit the limited thickness and high insulating properties
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Active controlled transdermal drug delivery systems' under Fifth Framework.

assistant: **Concept**

The proposal aims to develop functional materials and systems to fulfill the need for safe, actively controlled transdermal drug delivery. The effective combination of the partner's skills and resources will develop drug delivery systems to meet several patient centred objectives: e.g.wider use of self administered drugs , at home with a wearable system, more accurate matching of drug dose to drug need, avoiding side effects and long-term complications in chronic diseases (e.g. diabetes and osteoporosis) and improve patient compliance by replacing self injection. This project seeks to extend the scale and range of drugs currently administered non-invasively-e.g. beyond small scale anesthetics and pain killers. The economic impact is to reduce hospitalization, reduce use of PVC consumables and develop a new sector of European health industry .
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'An abstraction architecture for cognitive agents' in the context of a Sixth Framework call.

assistant: **Objectives**

The project will develop and validate a conceptual architecture for Cognitive Agents. The architecture will integrate the cycle of perception-knowledge acquisition-abstraction-reasoning-action generation. Special focus will be given in the abstraction architecture. The concept system is the representation of the knowledge that the agent possesses for its environment and itself. Objects, relations, goals, context information, and solution strategies are considered as knowledge about a situation. The abstraction mechanism is responsible for creating and organising a hierarchy of concepts while the reasoning process operates on the concept system in order to make inferences for virtual actions and select the one that will realise.The architecture will include attention control as a means of handling complexity, prioritising responses, detecting novelty and creating new goals. Both sensory and motor attention will exist. A goals-oriented computational model will fuse together user tasks with tasks originated from the agent. A goals generation system will enable the agent to produce its own goals. Reinforcement learning will provide the means by which the agent learns solution strategies for the satisfaction of a goal. The loop closes by having new actions modifying the current knowledge through perception. The architecture will be implemented in a robotics application, namely of robot navigation in an arbitrary outdoors environment but it will be in no way specific to this domain.Major requirements include survival, fast response and user-goal satisfaction. The robotic agent will learn about its own environment before becoming able to satisfy successfully any user goal. The process of retraining prior to becoming service-able will be re-iterated in any new environment. A nu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'SAFESEAT: the next generation, Smart Child Restraint Seat', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

There are 1.3 million children involved in motor vehicle crashes (MVC) each year. MVCs are a leading cause of death and injury among children <1 year of age. In Europe, each year 700 children are killed on roads and 80,000 are injured, representing an unacceptably high burden on Europe’s society and economy. Despite many initiatives being taken, progress made in child restraint systems (CRS) in the last decade is small compared to the advancements made in adult occupant protection in that same period.SAFESEAT is a new generation smart CRS based on breakthrough multiple-patented technology which sets a new level of safety to reduce child casualties and injuries in traffic collisions. By overcoming the limitations observed in the CRS state of the art seats, Mobius increases safety by a factor of 4 compared to statutory requirements, by a factor of 2 compared to the safest products on the market, and is far superior in terms of usability. The current project builds on the results of Mobius Phase 1 feasibility study; after validating user requirements, system performance, manufacturing viability and further, by establishing a clear route to market through a partnership with a major brand and distribution company for child safety seats products, giving SAFESEAT access to 24 distribution partners in 48 countries worldwide.Mobius applies to the SME Instrument Phase II to finalise and certify its final product according to the European homologation process. At the same time, Mobius will finalise the brand identity and the supply chain to be able to launch production at the end of the project and start entering all countries adhering the European Certification standards.


**Keywords:** Child Restraint Systems, Child Safety
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'AUdio models for RespiratOry and  cardiac diagnostics and clinical tRAining'.

assistant: **Innovation**

Human sounds, both bodily sounds (e.g., heart sounds) or voice, have been used by doctors for centuries as diagnostic signals for health and disease progression. However, while stethoscopes and microphones are very affordable, diagnosing through sound is a challenging task for medical professionals and requires years of training. The clinical training is generally based on shadowing experienced clinicians and repeating auscultation: this has scalability limits and imposes a considerable burden onto the health system.Machine learning for human sounds has beHuman sounds, being them bodily sounds (e.g., heart sounds) or voice, have been used by doctors for centuries as diagnostics signals for health and disease progression. However, while stethoscopes and microphones are very affordable, diagnosing through sound is a challenging task for medical professionals and requires years of training. The clinical training is generally based on shadowing experienced clinicians and repeating auscultation: this has scalability limits and imposes a considerable burden onto the health system.Machine learning for human sounds has been explored by the research community and is showing promise. In project ERC EAR we have advanced the state of the art in this respect for cardiac and respiratory health tasks. We showed that models could complement the skills of clinicians when diagnosing and constructed powerful and pioneering open pretrained models able to generalize to unseen cardiac and respiratory tasks with very good performance and limited labelled data for those tasks.In project AURORA, we will leverage the research results and develop a software framework that aids clinical training on respiratory and cardiac sounds and acts as a support tool for diagnostics. This will unlock the pote
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'A cost efficient, transparent and affordable digital procurement marketplace that allows MedTech industry and Hospitals to accelerate everyday processes'.

assistant: **Innovation**

Across Europe and the globe, there is unprecedented financial pressure on healthcare players and providers, which, in turn, makes the European MedTech landscape increasingly challenging. As public procurement becomes more sophisticated, price transparency is growing, and demand for integrated solutions is driving changes in product offers, requiring new sales channels and tactics. The procurement of medical products, equipment and technologies in the health system is complicated by suboptimal, duplicated or repetitive processes which increase costs and delays for all stakeholders. hystrix medical AG was founded in August 2017 and their mission is to drastically accelerate everyday processes in the healthcare sector and to realise substantial efficiencies for healthcare providers and MedTech suppliers alike, so that they can focus on what really matters, patient outcome. The hystrix medical marketplace is the first digital marketplace for medical products in Switzerland and Europe that extends beyond pure tendering support to provide Healthcare providers (HCPs) and MedTech suppliers with an accelerated procurement experience, access to transact at market prices, smart contracting between counterparties, automated approval processing, and the opportunity to significantly redeploy FTE time and cost to more value additive tasks. The hystrix marketplace provides top performance while reducing the procurement process from months to minutes and reducing costs by 40 to 50% on commodity product procurement. The estimated savings in the Swiss hospital sector alone from the introduction the hystrix marketplace is €324m (CHF365M i.e. CHF1.3 M per hospital on average across the 283 hospitals). The time and relative cost savings estimated for Switzerland are foreseen within the EU ma
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Catalytic Atroposelective Synthesis for Revealing Elusive Bioactive Conformations and Shapes' (AtropShape).

assistant: **Innovation**

Atropisomeric molecules (atropisomers) are separable conformational isomers arising from restricted rotation around a single bond. Atropisomers have revolutionized the treatment of several deadly diseases. The principal goal of AtropShape is to create pharmaceutical leads with unusual conformations and shapes by developing catalytic stereoselective (atroposelective) synthesis methods toward difficult-to-access drug-like atropisomers. Because atropisomers are chiral, they give rise to two or more isomers that have different pharmacological properties. These attributes relate to a crucial, yet minimally investigated and poorly understood fundamental question of how conformational changes, from achiral and relatively planar to chiral and more tridimensional atropisomeric forms, impact a molecule’s ability to interact with biological receptors. But to study such range of atropisomers and related concepts, one must first of all create them. Therefore, I will introduce three new catalytic atroposelective methods. (1) We will develop unprecedented atroposelective amide-bond formations and apply them to synthesis of the first examples of peptidomimetics with an atropisomeric amide moiety. (2) We will efficiently generate, by alkyne cyclization strategies, sphere-shaped atropisomers. This rarely investigated area of molecular shape is much sought-after in drug discovery. (3) We will introduce the first instances of atroposelective decarboxylation of esters. The proposed methods will offer direct access to an assortment of bioactive atropisomers, which will be easily modifiable to generate, by diversity-oriented synthesis approaches, libraries of drug-like molecules which will be tested broadly in medicinal chemistry. Collectively, the resulting knowledge will shed light on key d
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Disentangling the contributions of dopamine and amyloid burden to age-related changes in cognition and brain network connectivity in healthy older adults' (AMYDA), addressing dissemination and exploitation.

assistant: **Impact**

Normal aging is associated with declines in episodic memory and executive functions. Research suggests that around 20-50% of clinically healthy individuals show significant accumulation of amyloid, one of the hallmark biomarkers of Alzheimer’s disease but it has been difficult to establish the functional impact of amyloid burden in healthy older adults. Decreases in dopaminergic functioning in old age have been shown to mediate age-related changes in various cognitive domains. This project uses state-of-the-art positron emission tomography, functional magnetic resonance imaging and sensitive neuropsychological testing to disentangle the functional impact of amyloid pathology from those of dopaminergic effects on cognition in clinically healthy older individuals. It is hypothesized that dopamine and amyloid burden will have dissociable effects on cognition and brain network connectivity. The results of the proposed project will have important implications for characterizing the early preclinical phase of Alzheimer’s disease and aid the development of strategies for early identification of incipient neuropathological processes. The research will take place during the 24-months outgoing phase at Harvard University and Massachusetts General Hospital in Boston, MA, USA, and be followed by a 12-months reintegration phase at the Umeå Center for Functional Brain Imaging in Sweden. This IOF will lead to new insights into the neurobiological processes of cognitive aging and early Alzheimer’s disease, contribute to the accumulation of scientific skills and excellence in Europe, and enhance the career opportunities of a young female researcher in Europe.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Incredible journeys: How do multiple sensory cues allow animal migrants to precisely navigate to a distant goal?' (IncredibleJourneys) under Horizon Europe.

assistant: **Objectives**

Many animals, including birds, sea turtles and insects, perform spectacular long-distance migrations across the Earth. Remarkably, some of these accurately migrate between highly specific places thousands of kilometres apart, a navigational feat that is barely understood. Such precision navigation requires global compass cues to guide their long journey, and local cues at the destination to signal their arrival. I have discovered that the migratory Australian Bogong moth, with a brain size a tenth that of a rice grain, relies on the Earth’s magnetic field and the stars as global compasses, and on an odour signalling the final destination, to precisely navigate to a place it has never been before – a small alpine cave. The moth’s use of stars for long-range navigation is unique in invertebrates. But how is stellar and magnetic information sensed and integrated neurally to create precision navigation? Indeed, how do animals sense the magnetic field at all? This mystery, and its solution, is one of the greatest “holy grails” of modern sensory biology. With its simple and tractable nervous system, the Bogong moth may hold the key to solving these vexing questions. By tethering flying migratory moths in a flight simulator, and by using electrophysiology to record from sensory neurons in the brain, I will capitalise on our discoveries to make pioneering investigations of how magnetic, stellar and olfactory cues are sensed and integrated to create precise navigation. This will include aiming to identify and physiologically characterise the elusive magnetoreceptor. If I succeed, this will be a sensational discovery, opening the floodgates for international research on this little understood sense. Moreover, our recent advances in how the insect brain steers navigation will allo