RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Flexible and scalable digital-twin platform for enhanced production efficiency and yield in battery cell production lines' (BATTwin).

assistant: **Innovation**

Li-ion batteries are fundamental components for the energy transition of the European eco-system. Currently Europe lags behind Asia in terms of Li-ion battery cell manufacturing and more than 90% of the world's production takes place in China, Korea and Japan. To overcome this situation, there is an ambitious ramp-up plan of 25 new gigafactories in Europe with an expected value of €35 billion by 2030. However, in the ramp-up phase of these Gigafactories, a massive production of defects is expected, between 15% - 30%.  The new European Gigafactories will also bring demand for €150 bn of battery manufacturing equipment. To support this demand, the EU production equipment industry needs to fill the current knowledge gap and gain competitiveness towards Asian providers, grounding on its world-wide leadership in high-tech, green technologies, enhanced by industry 4.0 digital solutions, exploiting the European Zero-Defect Manufacturing paradigm. The objective of BATTwin is to support this scenario by developing a novel Multi-level Digital Twin platform towards Zero-Defect Manufacturing in battery production, that will reduce defect rates in battery production lines. The solution integrates four pillars, namely (i) a multi-sensor data acquisition and management layer, supported by data semantics through a Digital Battery Passport data model, (ii) process-level digital twins, modeling the critical stages of electrode manufacturing, cell assembly and conditioning through multi-physics, data-driven and hybrid approaches, (iii) system-level digital twins, based on simulation and analytical modeling, (iv) user-centric, goal-driven digital twin workflows, increasing the explainability of digital twins and driving the user in system design and control. The approach will be tested in
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Job Evaluation made easy for European SMEs. Unique innovative solution to perform digital job evaluation, compensation analytics and management in an easy, transparent and cost-effective way.'.

assistant: **Concept**

Problem: In Europe, only 49% of the organisations in the private sector use formal Job Evaluation schemes, with SMEs less than 3%. Lack of effective Job Evaluation procedures often results in unstructured wage payment practices and missed opportunities for requirements-based career and skill development of employees and costly litigations.Value proposition: 222.000 EU SMEs with 50-250 employees could benefit from gradar® platform. At only 5% take-up of the new SaaS by all concerned SMEs this could lead to around €1.1 billion savings and over 2000 new jobs across the SME sector.Solution: gradar® is a highly innovative, web-based single resource for SMEs for managing every aspect of the job evaluation process in an easy-to-use and cost-efficient way. Now, we are the only company worldwide that offers job evaluation together with a default model of relevant job specific competencies as a Software as a Service (SaaS) based product. nThe company’s algorithms are proactively audited for demographic (gender) bias.Product and technology: We are on the market with a first version of the product and already demonstrating over €90,000 (15-21% of total costs) per year savings from more efficient people utilisation and payment practices. This project will improve functionality and usability by enhancing the Competency module and implementing Compensation Analytics, Benchmarking and Management modulesCompetition: HR consulting firms like AON/Hewitt, Deloitte, KornFerryHay, hkp group, Kienbaum, Lurse, Mercer, PWC, Willis Towers Watson and a variety of micro players.Go-to-market: Target customers SMEs with 50-250 headcount from core markets Germany, Netherlands, Belgium, Italy, UK and Spain. Implementation partnership agreements in target areas to be finalized mid-2020. We have introdu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Epigenetic Disruption of Non-Coding RNAs in Human Cancer', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

In recent years, my laboratory, as well as others, have established the observation that epigenetic disruption, particularly in the DNA methylation and histone modification patterns, contributes to the initiation and progression of human tumors (Esteller, Nat Rev Genet 2007; Esteller, N Engl J Med 2008; Esteller, Nat Rev Biotech, In Press, 2010). Even more recently, it has been recognized that microRNAs, small non-coding RNAs that are thought to regulate gene expression by sequence-specific base pairing in mRNA targets, also play a key role in the biology of the cell, and that they can also have an impact in the development of many diseases, including cancer (le Sage and Agami, 2006; Blenkiron and Miska, 2007). However, there is little understanding about epigenetic modifications that might regulate the activity of microRNAs and other non-coding RNAs (ncRNAs), such as long non-coding RNAs (lncRNAs), Piwi-interacting RNAs (piRNAs), small-interfering RNAs (siRNAs), transcribed ultraconserved regions (T-UCRs), small nuclear RNAs (snRNAs), small nucleolar RNAs (snoRNAs), long interspersed ncRNAs (lincRNAs), promoter-associated RNAs (PASRs and PALRs) and terminator-associated sRNAs (TASRs) (Calin et al., 2007; Mercer, et al., 2009; Ghildiyal & Zamore, 2009; Jacquier, 2009). Our ignorance in this respect is even more significant if we consider these questions in the domain of cancer. Making best use of our expertise in several of these fields, my group will tackle the study of the epigenetic modifications that regulate ncRNA expression and how the DNA methylation and histone modifications profiles of these loci might become distorted in human cancer.  These findings could have profound consequences not only in the understading of tumor biology, but in the design of better mol
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Sense, Science and the Magic of Food'.

assistant: **Innovation**

The purpose of the SESAM - Sense, Science and the Magic of Food  is to create interest among young people at school and among citizens about the role of science in society by using the call for food systems transformation that is created by the climate crisis as the science case. The SESAM is bringing school youth, citizens and scientists involved in the bioeconomy and in curricular studies together around one open and public event in September 2-4 2020. The SESAM aims to demonstrate how young people and citizens by working together with academia and science can contribute to solving some of the urgent and complex sustainability challenges across global to local scales and multiple domains facing societies. The SESAM will be built around the idea of live Young Minds Food Lab that will form the physical frame for the events. The Young Minds Food Lab has been tested in several contexts at science and food festival as a way to highlight the commitment and importance of young peoples solutions to societal challenges. It builds on the idea of creating 21st century skills in learning workshops where pupil are challenged to address some of most important food and bio-economy relevant SDG´’s. The YouMiLa functions at the same time as a catchy and attention creating backdrop for the activities at the SESAM. The YouMiLa acts as a temporary science centre and includes a number of specific learning stations all manned by groups of 2.4 pupils all coached by a science teacher. All learning stations are involves one or more specific science principles from biology, chemistry and/or physics as well as one or more digital principles such as Artificial Intelligence, Virtual and Augmented Reality, Robotics, Biometrics, Coding and Data Science.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Making it happen - Scalable biphasic reactions using a nebulizer-driven continuous flow reactor' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

The original ERC grant focused on proving the power that oxygen from the air had in synthesis when its light-excited state was exploited. During the ERC program, we were able to show how simple & readily accessible start materials could be transformed into high value-high interest chemicals through straightforward “one pot” operations. We were also able to show that the diversity of structures accessible using this chemistry is remarkable. Furthermore, it is highly sustainable; representing a very efficient, benign & extremely low waste approach to the production of sought-after chemical frameworks. However, one problem prevailed. While it worked exceptionally well on a small research scale, its overall usefulness and its industrial relevance were severely curtailed by scale-up issues, even when the latest continuous flow technologies were applied. The need to achieve good light penetration, combined with the poor solubility of oxygen, seemed to castrate the potential of this chemistry to provide global solutions. A key breakthrough was made towards the end of the ERC program with the realization that creating and projecting a cloud (using a nebulizer to make fine droplets) into a light filled chamber could solve ALL the problems and lead to large scale reactions. With the current proposal, we seek to explore and fully automate this highly innovative nebulizer process in order to develop a robust prototype reactor with excellent prospects for further dimension enlarging (to industrial pilot plant scales & beyond). Furthermore, it is obvious that this “nebulizer fix” may also be superbly suited to other biphasic reactions. Our plan has the support of pharmaceutical giant AstraZeneca in the form of an automation expert who will act as mentor to the program. The PI & the a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Strategies for the protection of shipwrecks in the Baltic Sea against forthcoming attack by wood degrading marine borers. A synthesis and information project based on the effects of climatic changes', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Today the Baltic sea is a brackish marine environment, enclosing a unique well preserved historical collection of wooden shipwrecks and settlements. These objects and constructions are protected from aggressive marine borer due to the low salinity in the waters, and therefore it is one of the few localities in the world where  historical shipwrecks are found so intact and available for historical research. There are however strong indications, showed by the EU- MOSS project, that the marine borer Teredo spp is spreading into this area. If we are not able to protect the cultural heritage, these objects will be lost within a relatively short time due to the aggressiveness of the marine borers.  A strategy to handle this alarming scenario, is to provide the museums and conservators responsible for long term preservation of cultural heritage, with tools for predicting the spread of marine borers, and efficient methods for protection of the wreck, when the degradation is established. The WreckProtect project will therefore develop two guidelines synthesised on currently available information:  1. The prediction of marine borer attack in marine waters 2. The protection of wrecks in situ These guidelines will be applicable to other European marine waters outside the Baltic. The WreckProtect project is consequently a cross-disciplinary coordination action involving partners with expertise within geographical information systems, marine archaeology, marine biology, wood microbiology and conservation. These experts will through meetings and networking exchange knowledge and synthesise it into practical tools and methods in the form of  guidelines that will be  disseminated in a joint action for the European managers of underwater cultural heritage. A seminar, workshop and trainin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'INtegrated TOol chain for model-based design of CPSs' (INTO-CPS), addressing dissemination and exploitation.

assistant: **Impact**

The aim of the INTO-CPS project is to create an integrated tool chain for comprehensive model-based design of Cyber-Physical Systems (CPSs). The tool chain will support the multidisciplinary, collaborative modelling of CPSs from requirements, through design, down to realisation in hardware and software. This will enable traceability at all stages of the development.INTO-CPS will support the holistic modelling of CPSs, allowing system models to be built and analysed that would otherwise not be possible using standalone tools. We will integrate existing industry-strength tools with high Technology Readiness Levels (TRL 6–9) in their application domains. The solution will be based centrally around Functional Mockup Interface (FMI)-compatible co-simulation. The project focuses on the pragmatic integration of these tools, making extensions in areas where a needhas been recognised. The tool chain will be underpinned by a well-founded semantic foundations that ensures the results of analysis can be trusted.The tool chain will provide powerful analysis techniques for CPSs, including connection to SysML; generation and static checking of FMI interfaces; model checking; Hardware-in-the-Loop (HiL) and Software-in-the-Loop (SiL) simulation, supported by code generation. The tool chain will allow for both Test Automation (TA) and Design Space Exploration (DSE) of CPSs. The INTO-CPS technologies will be accompanied by a comprehensive set of method guidelines that describe how to adopt the INTO-CPS approach, lowering entry barriers for CPS development. The tool chain will be tested with case studies in railways, agriculture, building and automotive.The consortium has 4 academic and 7 industrial partners. The industrial partners comprise both tool vendors and case study owners. The INT
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'TUNABLE MATERIALS: PREPARATION, CHARACTERIZATION AND INVESTIGATION OF PHOTOCATALYTIC ACTIVITY OF NEW HIBRID MATERIALS' in the context of a Seventh Framework call.

assistant: **Objectives**

This project aims at developing new materials with tunable properties, conjugating good mechanical properties and photocatalytic activity. New and advanced materials will be synthesized on purpose, characterized and their efficiency as photocatalysts in abating pollutants such as pesticides and emerging pollutants will be evaluated.In the first stage, inorganic materials (TiO2, CNTs, graphene oxide) will be prepared and tested both in dispersed phase or added into a polymeric coating. For such aim, doped semiconductor oxides and carbon nanotubes (alone or combined with oxides) will be synthesized and tested. We also plan to conduct a detailed study of the charge transfer processes in the hetero-junctions to evaluate the factors providing the best performance of the hybrid materials. In addition, the efficiency of surface photochemical processes will be estimated in terms of the quantum yield of surface chemical transformation.In the second stage, preparation and characterization of new UV-cured polymeric materials containing at the same time CNTs or graphene and semiconductor oxides will be carried out, with the aim of exploring the synergistic/antagonist effect of the fillers in the photodegradative process followed by pollutants.For both stages, we plan on investigating the semiconductor properties of the inorganic material and its efficiency in the abatement of pollutants both when the catalyst is dispersed in water or when the target molecule is adsorbed on a polymeric film containing the catalyst dispersed into the network. The polymeric films will be employed for the degradation of pollutants in water or gas phases. In all cases, we will evaluate the initial degradation of the molecule, identify the transformation products and measure the toxicity of the system.Fi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Hide and Seek with Cancer Drugs' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Cancer is one of the most prominent causes for morbidity and mortality in industrialized countries. The key challenge in drug-based anti-cancer therapy is to efficiently kill the cancer cells while minimizing side-effects on healthy parts of the body. The DeShield project will establish the proof of concept for a novel approach to upgrade existing anti-cancer drugs in a way that the anti-cancer effect will be increased while side-effects will simultaneously minimized. DeShield technology will be used to shield approved anti-cancer drugs while circulating in the body in order to minimize side effects. Once the shielded drug accumulated at the cancer site, an external stimulus will be applied to trigger de-shielding. The drug will then locally and specifically be taken up by the cancer cells to exert its therapeutic effect. We have successfully demonstrated the functionality of the DeShield technology using the clinically approved anti-cancer drug Doxil and human cancer cell lines: when the shield is intact, the drug is not taken up by the cells, only upon inducible un-shielding the drug enters and kills the cells. In the DeShield project we aim at establishing the Proof-of-Concept that this approach is functional in cancer animal models, that it increases the therapeutic effect while minimizing side-effects. To this aim we have assembled a team with high expertise in complementary areas covering the technology itself, the conductance of preclinical animal studies up to clinical trials as well as business expertise. The technical advance obtained in this project together with a comprehensive market research and the development of a business strategy will shape a highly attractive commercial proposition for the successful valorization of our ERC-funded research.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Solar Powered Thermochemical Heat Storage System' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

The EU promotes the use of renewable energy for the reduction of CO2 emissions as part of the EU’s effort to protect thenatural environment. It aims to reduce carbon emissions by 60% relative to the 1990 level by 2050 and increase the use ofrenewable energy to 20% by 2020. Buildings account for about 40% energy consumption in the EU and the use ofrenewable energy for heating and cooling of buildings will be important in achieving this goal.Transformation of the EU new-existing building stock towards low/zero energy buildings requires effective integration and fulluse of the potential yield of intermittent renewable energy sources. Thermochemical heat storage (THS) can play a pivotalrole in synchronizing energy demand and supply, on both short and long term basis. The proposed solar poweredthermochemical heat storage (Solar-Store) system will integrate solar collector, evaporative humidifier and heat pipetechnology with a novel THS reactor design for seasonal storage of solar energy. The proposed system will deliver efficient,low-cost THS that can be fitted in the limited space in dwellings. The fellowship aims to benefit from Prof. Yijun Yuan’srecent work in energy storage systems, making use of sorption materials and solar thermal technology. Professor Yuan'sconsiderable industrial and academic experience will make valuable contribution to the EU host organisation in terms oftechnology/knowledge transfer, PhD student/young researcher training and IP/commercialisation of new technologies. Thepartner organisations will also involve to this interaction (secondments) to enhance the effectiveness of the fellowship.Combining the skills and experience of UNOTT, Prof. Yuan and partner organisations and presenting them to the nextgeneration of researchers and professionals in i