RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Food Loss in History. Insights into the food produced but never consumed' (FoodLoss) under Horizon 2020.

assistant: **Objectives**

This project outlines a study on food losses in Modern Times which explores reasons,magnitude and features of food wastage in the past. The research will focus on northern Italy, although, whenever allowed, a comparative perspective will be adopted, providing insights into the European scenario. By ‘food loss’ literature refers to the food produced and yet turned inedible for a number of reasons: nowadays, as well as in the past, food loss accounts for a significant part of the overarching term ‘food wastage’. Essentially food loss remains distinct from ‘food waste’, since the former takes place at production, post-harvest and processing stages, whilst the latter, much more widely debated, occurs only at the end of the food chain. Focusing on well-documented and highly representative case-studies,this research will investigate the incidence of grain losses as a whole, its core features and its main consequences against the backdrop of pre-industrial Europe. Accounting records combined with relevant scientific literature of the time will cast a light on grain losses occurring at  storage and processing stages. By bringing new data on cereal preservation in a chemical-free setting, this study will provide an original contribution to the current food wastage debate.Unlike food waste, commonly treated as a cultural phenomenon, food loss tends to be accounted as a mere technical issue, therefore disengaging humanities and social sciences specialists as a whole. This study will highlight to what extent cultural aspects, such as scientific knowledge, belief system and local policy would play a role in this process. As a matter of fact, food loss is still nowadays considered as a prominent issue even in areas endowed with adequate facilities and avant-garde technologies, pointi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Label-free multimodal real-time imaging of phage-induced bacterial lysis' (COBLIM).

assistant: **Innovation**

The fast-growing number of multidrug-resistant bacterial strains is one of the biggest threats to public health. 5 million deaths and billions of euros are associated with drug-resistant bacterial infections per year. Lately, bacteriophages have become an alternative way to increasingly failing traditional direct-acting small antibiotic molecules. However, a deep and detailed understanding of the processes connected to bacteriophage-induced bacterial lysis is still missing. This project aims to develop a unique optical-based multimodal imaging technique for high-speed real-time imaging of phage-induced lysis of bacteria. The suggested tailored combination of coherent brightfield microscopy allowing for fast, label-free, and long-term single bioparticle imaging with advanced electro-optic fluorescence lifetime imaging allowing for dynamic molecular proximity sensing will be a worldwide unique prototype. For the first time, the technique will allow for direct label-free tracking of bacteriophages and simultaneous detection of changes in the inner bacterial environment (e.g., change in pH) and bacterial metabolism during all stages of infection. This will provide a great pool of information currently lacking, that will facilitate and accelerate phage and antimicrobial research. The method can be easily adapted for other bacterial or mammalian cells and single-bioparticle and particle studies, finding its place in drug delivery, cell interaction studies, or tracking particles in cells. Due to the uniqueness of the set of information that currently cannot be gained (under the same conditions) with any other technique, we expect the technology to become standard in future life science imaging.


**Keywords:** Real-time single bioparticle imaging, Bacteriophage induced bacteri
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'The end-Cretaceous extinction and Paleogene recovery of mammals: evolution during a period of intense environmental change' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

How do organisms respond to environmental change? Answering this question is an essential challenge in contemporary scientific research, as it will help us understand—and better prepare for—the rapid pace of current climate change. A striking example of major environmental change in the geological record is the ~30 million years bracketing the Cretaceous-Paleogene boundary (66 million years ago), a time that witnessed a sudden mass extinction that killed off the dinosaurs and an ensuing recovery that vaulted mammals into a dominant role in terrestrial ecosystems during a time of fluctuating climates. This project aims to better understand the end-Cretaceous extinction and Paleogene recovery of mammals by integrating information from a wealth of new fossils, phylogenetic analyses that put these fossils into genealogical context, and cutting-edge quantitative and evolutionary modelling techniques that establish major trends in mammalian evolution and test how these trends were related to environmental change. We will focus on three major mammal groups as exemplars: Metatheria, Taeniodonta, and Pantodonta. We will comprehensively describe the anatomy of five critical species of Paleogene mammals from these groups, which will provide data for genealogical analysis. Next, we will conduct genealogical analyses showing the within-group relationships of these three exemplar groups, and place them on the broader family tree of mammals. Third, we will use these genealogies to quantify rates of species evolution, body size evolution, and anatomical character change in these mammals during the Cretaceous-Paleogene. Fourth, we will evaluate the relationship between Cretaceous-Paleogene mammal diversity and evolutionary rates with changing climates. Taken together, these analyses wil
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'A low cost Mosquito Contamination Device for sustainable malaria mosquito control' (MCD), addressing dissemination and exploitation.

assistant: **Impact**

Our consortium will focus on the integration of four novel control components in a low-tech (no power source, no need for CO2) and cheap mosquito contamination device (MCD) that will a) lure malaria mosquitoes to an attractive point source, b) infect them there with a fungus as a slow-killing agent, and c) expose them to a juvenile hormone analogue with which they will contaminate their breeding sites and kill mosquito larvae. This is unique because it will be the first vector control tool that targets both adult and larval mosquito stages simultaneously with environment-friendly control agents. We foresee the use of MCDs mostly in the outdoor environment where they will lure, infect, and contaminate host-seeking and resting females. Together with the excito-repellent properties of insecticides used for indoor spraying and bednet impregnation, and possibly spatial repellents, MCDs will serve within a push-pull framework. We aim to develop a low-cost MCD that operates uninterrupted and without maintenance for prolonged periods of. MCDs will be highly useful in areas where insecticide-resistance is hampering the effectiveness of current vector control tools and where behavioural adaptation of mosquito populations has shifted towards outdoor resting and biting. Our goal is to have several prototypes of MCDs in an advanced stage of development and ready for industrial production at the end of this 3-year project. By then, extensive (semi-)field testing in Tanzania and various other countries will have been completed. This proposal brings together a unique mix of business-oriented and academic/institutional partners with a broad range of expertises in fungus and mosquito biology, mosquito behaviour, trapping technology, materials sciences and entrepreneurial interests. We wi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'UNVEILING THE ROLE OF SUMOYLATION AS NOVEL MOLECULAR PATHWAY IN MYELIN BIOLOGY;  IMPLICATION IN NEURODEVELOPMENT AND DEMYELINATING PATHOPHYSIOLOGY.' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

SUMOMyePath:  a New Pathway to Wrestle Demyelinating diseases.(Re)myelination is the process by which Oligodendrocyte Precursor Cells (OPCs) migrate and differentiate and mature into myelin generating Oligodendrocytes (OLs). Understanding this process is key to cure demyelinating disorders of which, Multiple Sclerosis (MS), is the most prevalent, affecting 2.8 million individuals worldwide and specially women (69%).  SUMOylation is a post-translational modification mainly studied in neurons within the central nervous system, however its pathway’s role in oligodendroglia and its relation with myelin (patho)physiology remains to be investigated. Thus, it is an exciting field to explore and SUMOMyePath will address this challenge by synergizing the applicant’s experience in SUMOylation and myelin biology and the expertise of 1) the host group´s (UniTo) in OPCs biology and 2) the secondment group´s (Ubx) in state-of-art live-imaging of OL lineage cells, opening novel avenues of research and, as consequence, new diagnostic and therapeutic strategies.


**Keywords:** Myelin,  SUMOylation,  Oligodendrocites,  OPCs,  Demyelinating diseases,  Multiple Sclerosis,  Remyelination,  SUMO pathway,  Sox10
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Cold Spray  Radical Solutions for Aeronautic Improved Repairs (CORSAIR)'.

assistant: **Concept**

CORSAIR project is a wide investigation concerning the capabilities of Cold Spray Technology for maintenance and repair of aeronautic frames and components. Today, deep and systematic investigation in Cold Spray is required to better understand the capabilities and fully validate the technology in aeronautics. In this scenario, the activities planned in CORSAIR project are (1) Explore the real capabilities of Cold Spray in several practical examples of aeronautic repair applications; real components to be repaired will be selected by aeronautic companies and cold spray repair protocols defined during the project. A condensed list of the parts and repairs considered during the project includes the Repairs of New Parts: castings and machined parts exhibiting different kind of defects; and the Restoration of Serviced Parts and components. The Base and deposition Materials are Light Alloys such as Al, Ti and Mg alloys. Homogeneous Repair (repair where the deposited material is the same of the base material) and Heterogeneous Repair (repair where the deposited material is different with respect to the base material) will be considered. (2) deep investigate the coating and repair characteristics (mechanical, microstructural, thermal and chemical properties) in order to finely tune and define where Cold Spray could be further applied for maintenance and repair in aeronautics. (3) deep investigate the effect and the characteristics of feedstock materials required for deposition (4) to give the required reliability to the coating deposition and repair processes to validate the technology for aeronautic industry. (5) To surpass the actual technological limitations of line-in-sight Cold Spray deposition process developing new nozzles for out-of-view surfaces. (6) To develop a New
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'A gel-network depot for bringing advance strategies for skin cancer' in the context of a Horizon 2020 call.

assistant: **Objectives**

GELNANODEP aims at inserting in the background of the advance drug delivery systems an innovative clinical treatment for skin cancer diseases as melanoma. The main goal of GELNANODEP system is to exploit a synergic therapeutic anticancer approach by using a gel depot loaded natural bacteriophages and a natural bio compound encapsulated with surface engineering nanoparticles. This project intends to propose a novel and alternative approach to avoid the usual severe side-effects affected by the systemic administration of the anticancer pharmaceuticals (e.g., intravenous injections or oral). So, the transdermal drug delivery system is proposed as alternatives that offer promising strategies for the treatment of skin tumours. Melanoma is a skin cancer which can become metastatic, drug-refractory, and lethal if managed late or inappropriately. Besides these already complicated conditions, it is largely known how the depletion of the immunological defence system of the cancer patient can induce infections by opportunist microbial pathogens such as bacteria and fungi. Pathogenic microorganisms with cancers have been reported frequently associated with chronic inflammation in skin malignancies, which can promote skin carcinogenesis inducing the ulceration of cutaneous lesions, and last but not list increasing patient mortality.The GELNANODEP system provides a depot based on a thermosensitive biodegradable and biocompatible triblock copolymer carrying: (I) surface engineered nanoparticles to specific target alpha 2-beta-3 integrin expressed on tumour cells and selective release sulforaphane which is a natural dietary isothiocyanate mostly characterized by its potent anticancer activity, and (II) naturally bacteriophages inducing the death of pathogenic bacteria.This proposal wil
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Extreme Astrophysics: Ultra-compact binaries and gamma-ray bursts' (2007-2013).

assistant: **Innovation**

We propose a research project to work within the field of extreme astrophysics, on ultra-compact binaries and gamma-ray bursts. In particular we wish to understand the role of compact binaries as gamma-ray burst (GRB) progenitors, the formation of compact binaries in the field of our Galaxy and the production of interacting binaries in globular clusters. We will approach these connected problems in four different ways. First, we will predict the galactic offsets of short GRBs, using our detailed binary stellar evolution code to compute the evolution of the binaries most important for their production. Some events in compact binary evolution that proceed on hydrodynamical timescales will be modelled using smoothed particle hydrodynamics (SPH). We shall further use the predictions to model the wind outflows from the binary and single-star progenitors of long gamma-ray bursts to determine if the two can be distinguished. Secondly, we shall use a detailed stellar evolution code to compute the evolution of ultra-compact binaries in the field, to better understand the origins of some of their observed properties. Thirdly, we shall use a code that combines detailed stellar evolution and N-body dynamics to model the evolution of the progenitor binaries of gamma-ray bursts in dense stellar environments. Finally, we shall estimate the production rate of LISA-visible binaries in the field and in globular clusters from the models mentioned above. To achieve this scientific programme we intend to recruit Ross Church as a fellow. Church is an expert in stellar evolution and N-body dynamics, and his computer code that combines the two is a unique research tool for the investigation of stellar evolution in dense stellar systems such as the core of a globular cluster. His recruitment wi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Smart Synchronous inverter for grid’s stability' to be submitted under Horizon 2020.

assistant: **Abstract**

The integration of Renewable Energy Sources (RES) and Distributed Energy Resources (DERs) plays a fundamental role in the development of Smart Grids. Nowadays, RES (solar, wind, etc.) and DERs (energy storage, EV, etc.) are connected to the grid via DC/AC converters (inverters). Now, these inverters do not provide ancillary services (power-frequency control, voltage control, etc.) like the synchronous generators (generators normally used in conventional power plants) do, which is required to avoid grid voltage and frequency fluctuations and faults. Since the amount of RES and DERs installations are drastically increasing in the world, there is an urgent need to implement smart inverters with these functionalities included. The Synchronverter facilitates the connection of RES and DERs to the grid causing a conventional inverter to mimic a synchronous generator, consequently, these power sources can actively participate in the grid stabilization in harmony with other generators. The Synchronverter has been developed by Synvertec an Israeli company seed-funded by Horizon Green Tech Ventures an investment alliance formed by Alstom S.A, Rotem Industries Ltd (Isralei company specialized in the commercialisation of advanced technologies) and Gefen Investmens ( a business incubator company). Synvertec is also participated by Israel Electric Corporation (IEC - Israeli Grid Operator) and the Office of the CHief Scientist (Israeli goverrmental R&D fostering office). Only the inverter’s market for renewable energy accounts for more than $11 billion in 2014. Synvertec aims to make a gradual approach by initially addressing inverters for PV and DES accounting for more than $7 billion in 2014 (out of which $3 billion in Europe). The benefits that this technology will bring to the mark
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Supporting international mobility and training in Bizkaia', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

The B-MOB project objective is to provide the researchers the opportunity to deepen and widen their skills, by increasing their transnational mobility, adding different and complementary research competences at an advanced level, reinforcing their own professional maturity and experience. The project also wants to pave the way to make the research profession more attractive and interesting for young researchers. The project aims to exploit synergies between Community actions and those at Regional/National level, in order to increase their numerical and qualitative impact (in terms of supported researchers) and in order to combat research fragmentation.Moreover, this project will enable Biscay to reinforce its scientific capacity, by strengthening our networks abroad and reaching an adequate number of researchers, assuring the development of the research activities and of the economic growth of Biscay and of Europe, and thus, contributing actively to the ERA.The programme comprises three complementary actions, which will give researchers the opportunity to develop, while working at high-level research institutions of Biscay and worldwide, a project fitting their individual needs; to benefit from advantageous working conditions and all of the necessary benefits for this new step of their career. These three actions are:-Support the integration of experienced researchers in Biscay-Support to the linking of external collaborators who participate in innovative projects in Biscay-Support for the training of qualified people abroad, with a return phase to BiscayBizkaia:xede presents this project for additional support by the Marie Curie Programme. The association has been created in 2004 with the purpose of developing an integral territorial strategy of talent management and h
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Quantification of the distribution of radiation doses received by humans through the various pathways in a contamined indoor environment' goes beyond current state-of-the-art under Fifth Framework.

assistant: **Innovation**

The influence of range of factors on the potentially highly significant doses received from contaminant deposition to humans is currently not well understood. The objective of the proposed project is to generate extensive and wide-ranging data to address this problem. A collaborative experimental programme involving new techniques is designed, which will be used to achieve this objective. Parameter values will be quantified, which can be used to greatly refine EU standard release models, such as COSYMA, as well as in connection with dose assessment in the workplace. The experimental data will form the necessary foundation for the ultimate project goal: the provision of a holistic model of radiation doses received through the various pathways of gas and particle exposure in a contaminated indoor environment.