RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Risk and Opportunity management of huge-scale BUSiness communiTy cooperation'.

assistant: **Objectives**

Online communities generate major economic value and form pivotal parts of corporate expertise management, marketing, product support, CRM, product innovation and advertising. Communities can exceed millions of users and infrastructures must support hundreds of millions discussion threads that link together billions of posts. Current solutions fail to meet current challenges of scale and growth, let alone support for understanding and managing the business, social and economic objectives of the users, providers and hosts involved. Extensive research into novel solutions is required to deal with both the large-scale data management and analysis tasks as well as to understand and manage complex user behaviors and ecosystems in online business communities.ROBUST will create models and methods for describing, understanding and managing the users, groups, behaviours and needs of online communities. A highly scalable cloud and stream-based data management infrastructure will handle the real time analysis of large volumes of community data. Simulation and visualisation services will support detailed understanding, prediction and exploration of possible actions. A risk management framework will combine these tools within a methodology for the detection, tracking and management of both opportunities and threats to online community prosperity.Live industrial testbeds from SAP and IBM provide practical grounding and serve to assess project success. Applications include online communities in internet, extranet and intranet settings addressing customer support, knowledge sharing, and hosting services. The variety of testbeds will ensure generality of our approach as well as place stringent requirements on data volumes, scalability and real-time analysis. A virtual centre of excellen
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Questions relating to rectifiability and singular integrals, and packing measures' (1994-1998), addressing dissemination and exploitation.

assistant: **Impact**

A major objective of the proposed research is to extend the applicant's fields of expertise, by allowing her the opportunity to collaborate with one of the most active senior mathematicians working in her area. It is proposed to consider some of the open questions in the areas of Rectifiability and Singular Integrals, and Packing measures. The applicant's work to date has centred on the latter topic, in particular on the question of subsets of positive finite packing measure. The proposed work would thus continue this earlier work in a logical and satisfying fashion, and also extend into related areas which are currently very active. Some of the specific questions we would wish to consider are: 1. The characterization of removable sets of positive length for bounded analytic functions. 2. The curvature characterization of rectifiability and pure unrectifiability. 3. Results concerning the packing dimension of intersections of sets in n-dimensional Euclidean space.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'BiPhySO: Combatting critical uncertainties in biological vs. physical drivers of future oxygen budgets in the Southern Ocean'.

assistant: **Innovation**

The Southern Ocean is one of the most biogeochemically-important regions on Earth, representing a critical region for inorganic and organic carbon sinks. However, regional differences and logistical challenges, make general statements about Southern Ocean processes difficult and inaccurate. To get a more accurate understanding of the Southern Ocean and globe, direct comparisons of key processes between regions are needed. Here I will use sensor-based measurements of dissolved oxygen and particulate backscatter to calculate these key biogeochemical rate measurements during the December-January productive season using the novel but already-proven equations. I propose to leverage pre-existing glider and other autonomous asset datasets from three major research programs to the Ross, Amundsen, and Weddell Seas in a novel manner to generate estimates of net community production (NCP) and carbon export that are of higher spatiotemporal resolution and more consistently-produced than ever before. In this two year project, entitled BiPhySO, I will parameterize the key biological and physical processes individually, enabling me to assess their importance in NCP calculations and export through time and in each Antarctic sea, individually. I will apply these findings to earth system models in order to forecast future Southern Ocean production-export dynamics under climate change. BiPhySO will be conducted with Professor Karen Heywood at the University of East Anglia (UEA) with secondments at the Instituto Nazionale di Oceanografia e di Geofisica Sperimentale (Italy) with Dr. Gorgio Dall’Olmo and at the National Oceanography Centre (UK) with Professor Stephanie Hension. BiPhySO will expand my current skillset to better include glider and profiling float experience and make my current
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'ONLINE MULTIMEDIA INFORMATION FOR MAINTENANCE AND OPERATION'.

assistant: **Concept**

OMIMO will prepare the specification and design aspects a demonstrator of a maintenance documentation system for a commercial turbo-fan aircraft engine. The system will provide on-site delivery to maintenance operations of documentation for the maintenance of the engine, integrated with telematic functions such as queries and videoconferencing with support organizations. In demonstrating applications, the database will be self-contained while enabling development within the constraints of the project. Improvements in aircraft maintenance resulting from OMIMO will reduce costs, enhance safety, and lead to increased efficiency for the aircraft and airline industries.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Efficient deduction in first order logic with equality by combining semantictableaux and integer programming' under Fourth Framework.

assistant: **Concept**

The basis of the proposed project is an Automated Reasoning system developed at the University of Karlsruhe, that makes use of the idea of combining semantic tableaux and integer programming (IP): A formula (propositional or first-order) is transformed into an IP problem, and then IP methods are used to check whether the formula is satisfiable. The objective of this project is to extend the existing implementatio] (available when the project starts) and to unveil strongholds and problems of the method. Strategies and heuristics will be developed to utilize advantages, overcome problems and, thus, improve the method. This is an important and critical phase in the development of an Automated Reasoning system - even more in this case, since a calculus is implemented that has not been used before. In addition, a method will be developed for extending the combination of semantic tableaux and IP to handle first-order logic with equality.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Stretching soft matter performance: From conformable electronics and soft machines to renewable energy' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

This project aims at exploring the unique properties of soft matter, inimitable with conventional solid materials, to extend basic knowledge and to trigger novel applications. Three core objectives going far beyond the state of the art are tackled: in conformable electronics stretchable ferroelectrets and rechargeable batteries promise novel electronic items. The groundbreaking approach of this proposal is the development of stand-alone stretchable electronic items including sensing capabilities for touch and other environmental stimuli, information distribution, as well as power generation and distribution. Such devices can be used in soft robots, artificial limbs and morph designs. The second objective on soft machines addresses electromechanical instabilities in soft transducers, leading to giant stroke actuators, enabling programmable Braille readers and tactile feedback in consumer electronics. Stretchable nonlinear optical materials allow for efficient phase-matched operation, opening new research fronts in adaptive photonics. The third objective on renewable energy concerns mechanical energy scavenging from environmental sources. We focus on water as electrode in deformable capacitors and as gap filling dielectric in variable capacitors. Efficient operation cycles maximizing energy of conversion are developed. The wide range of objectives, but also the possible applications require expertise in thermodynamics of soft matter, in electrical and mechanical engineering and in device implementation. The challenge of the overall approach is to base research on materials from renewable sources. We expand knowledge in applying soft materials in conformable electronics, soft machines and energy harvesting and contribute to general challenges in sustainability and energy s
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Immune-Me-on-a-Chip: A Personalized-Immunized-Human In Vitro Platform for Studying Human Physiology and Biological Threats' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

Understanding how the adaptive immune system works is of monumental scientific importance. It is remarkable, then, that despite the sophisticated modeling technologies available today, there are no human-relevant in vitro platforms mimicking the adaptive immune system in a physiological environment. Rather, state-of-the art models involve animals or in vitro systems that capture isolated elements of the immune response (e.g., activation by tumor cells). The challenge in developing immunized in vitro models is that adaptive immune cells cannot be co-cultured with non-autologous tissue, as they become activated and destroy it. We propose a groundbreaking paradigm that tackles this challenge, while advancing the greater ideal of personalized medicine. The approach builds on my expertise with the Organ-on-a-Chip: a microfluidic platform comprising human tissue that closely mimics organ functionality. I will create a novel platform integrating six vascularized Organ-Chips, all originating from iPSCs derived from a specific individual, which have been differentiated into specific tissue types. This fully isogenic platform will accommodate the donors adaptive immune cells: Because they originate from the same source, they will not be activated. Indeed, preliminary results support this hypothesis. The resultant system, Immune-Me-on-a-Chip, will constitute a first-of-its kind personalized-immunized-human platform for studying human physiology and biological threats. I will use the system to explore fundamental biological questions: (i) understanding how different isogenic and non-isogenic tissues interact with the immune system, e.g., in organ transplantation; and (ii) identifying how pathogens (antibiotic-resistant E. coli), as well as antibiotic treatment, affect human physiol
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Web Services - DIAgnosability, MONitoring and Diagnosis' (WS-DIAMOND), addressing dissemination and exploitation.

assistant: **Impact**

Self-healing software is one of the challenges for IST research. This project aims to take a step in this direction by developing a framework for self-healing Web Services.The project will produce:-an operational framework for self-healing service execution of conversationally complex Web Services, where monitoring, detection and diagnosis of anomalous situations, due to functional or non-functional errors (e.g., Quality of Service) is carried on and repair/reconfiguration is performed, thus guaranteeing reliability and availability of Web Services;-a methodology and tools for service design that guarantee effective and efficient diagnosability/repairability during execution;-demonstration of these results on real applications.The research is risk-bearing. It builds upon results in different areas such as model-based diagnosis, semantic Web Services, cooperative information systems, and Web Service composition. It goes beyond a number of current projects in the area of Service Oriented Computing and Semantic Web Services, which do not consider the monitoring, diagnosing and repairing of Web Services.The research is timely because the progress in model-based diagnosis and the emergency of Web Services standards that occurred in the last decade has reached sufficient foundational advances to make the proposed research feasible.The research is important because the Web Services technology has a tremendous potential for the creation of complex services to support e-commerce and human activities, creating networks of co-operating e-services. These networks are open and may accommodate dynamically the addition and removal of new services and the disappearance of other ones. Such networks are, however, hindered by the inherent complexity and difficulty in controlling such comp
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Coordinated activity of midbrain dopaminergic neurons during cognition and in rodent models of schizophrenia' (2002-2006), addressing dissemination and exploitation.

assistant: **Impact**

This project will use state-of-the-art electrophysiology in freely-behaving rats to record simultaneously from networks of multiple single neurons in the ventral tegmental area (VTA) of the midbrain during maze-based cognitive tasks. Hippocampal (HPC) and prefrontal cortical (PFC) activities are coupled in the 4-12 Hz theta frequency range.When selectively enhanced, this coupling allows the PFC to direct behaviour appropriately by integrating spatial information from the HPC into a broader, decision-making network. Thus coordination of theta rhythms constitutes a mechanism through which the relative timing of disparate neural activities can be synchronized.This project's central hypothesis is that dopaminergic projections from VTA to both HPC and PFC mediate or modulate this rhythmic coordination according to reward-related parameters encoded in the VTA during cognition. Dysfunctional dopaminergic neurotransmission, neural synchrony and working memory are all implicated in schizophrenia. Recordings will therefore be used to detail the nature of VTA activity in rat models of schizophrenia.Future work will combine simultaneous recordings from VTA, HPC and PFC with pharmacological and genetic manipulations made using lentiviral vectors, addressing both fundamental mechanisms of brain function and the neural basis of psychiatric disorders. Through this work, Dr. Matthew Jones will continue to establish his independent research program in the EU, having learned and applied the latest tetrode recording techniques and analyses in the US.His neuro-scientific interests and experience, research environment at the University of Bristol and growing network of UK, EU and US collaborators are all absolutely aligned with the FP6 bid to study 'Cortical information processing' and 'Schi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Long-term effects of damage in persons exposed to a radioactively contaminated environment' (ENVRAD).

assistant: **Concept**

The aim of the proposed multidisciplinary research project is to identify long-term effects of radiation to persons acutely and chronically exposed to a radioactive environment. New fast, sensitive and reliable high-throughput methods (microplateassays) will be introduced and evaluated for the surveillance of people living in territories severely contaminated with radioactive material (due to accidents involving large-scale release of radio-activity; Chernobyl disaster). In addition, the long-term effects of exposure to radio nuclides on the immune system and on the incidence of congenital malformations will be studied.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Exploration of genomic and metabolite diversity of a novel group of abundant soil bacteria', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

This proposal aims to initiate the exploitation of novel predominant soil bacteria and to reveal their evolution. Recently discovered Gram-positives represented 20%of all soil bacteria in a Dutch grassland area and are at least in partculturable. Their high competitiveness among other bacteria may suggestantimicrobial activity. Thus, our SME partner who provides straightforward exploitation of active compounds will screen them for health-related secondary metabolites. Their evolution, as visible in their micro diversity, will be investigated by genome analysis. With DNA/reran based techniques we will follow their dissemination through the Netherlands and beyond. Different populations will be located and compared for evolutionary relationships. We will describe the most important soil bacteria hitherto cultured and track their adaptation to different niches and their dissemination through European landscapes.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'Transcriptional control of the human leucocyte common antigen'.

assistant: **Objectives**

The project aims to identify transcriptional control elements of the human leucocyte common (CD45) antigen. Because of the large size of the human CD45 gene, we shall take advantage of the much smaller genome size of the Japanese puffer fish, Fugu rubripes. We shall clone the Fugu CD45 homologue by low stringency hybridisation screening of a splenic cDNA library or amplification of leucocyte cDNA using degenerate oligos. The Fugu CD45 cDNA will be used to probe a cosmid genomic library and the gene will be cloned and sequenced. Likely transcriptional control sequences will be identified by sequence analysis, subcloned into CAT vectors and tested for promoter and enhancer activity by transfection into Iymphoid and nonIymphoid lines. The human homologues of transcriptional control regions will be identified, cloned and tested by similar methods. Human tissue specific elements will also be tested in vivo by construction of transgenic mice. Training content (objective, benefit and expected impact) The proposed project will provide training in a range of molecular biology methods and in the analysis of gene expression using transient transfection assays and transgenic mice. It will provide information on the control of expression of an important gene product of leucocytes, perhaps Ieading to new insights into how differentiation of leucocytes is regulated. Links with industry / industrial relevance (22) The Edward Jenner Institute for Vaccine Research will discuss with Glaxo Wellcome the commercial exploitation of any patentable discoveries arising from this project.