RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Quantifying urban mines in Europe and related implications for the metal-energy-climate change nexus' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Securing access to raw materials is of particular concern for countries highly dependent on imports. This is the case of many EU States. Because of issues related to decreasing ore grades and scarcity of supply of primary metal forms, recycling of above-ground deposits of metal-bearing waste (or “in-use stock”) will become an increasingly important means of securing resources to provide essential building blocks to the European industry. Recycling of metal in-use stock has the further potential of avoiding consuming the large amounts of energy required in primary metal production, and of reducing related greenhouse gas emissions. Currently, however, because of metal losses during and after use, end-of-life recycling rates for many metals are often very low, so the potential for improving those recycling efficiencies is an important consideration for the achievement of a more resource efficient economy and sustainable development in Europe. This project proposes a comprehensive, exemplary research line that merges complementary drivers in the assessment of the metal-energy-climate change nexus for (i) estimating the size of current urban mines for selected, critical metals; (ii) assessing future opportunities and barriers to their recycling, and (iii) related potentials for carbon emissions reduction. The results of this project are expected to reach a wide impact in the research community and will timely inform an evidence base for future decision-making, and for enhancing the growth of European economy improving resource efficiency and recycling. While pursuing the objectives of this high-quality research proposal, the candidate will acquire new, desirable knowledge and competences that will open to him the best opportunities for achieving a leading position in researc
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Privacy Matters'.

assistant: **Innovation**

With the rapid increase in technological means for personal information capture and surveillance and the use of Artificial Intelligence, there is growing challenge to establishing and maintaining individual privacy. One important factor contributing to the erosion of privacy is the growth in biometric person recognition technologies. Another is the increasing possibility for extensive data mining, allowing for the aggregation, linkage and inference of personal information of individuals active on the internet. With the ubiquity of sensors (in mobile devices, CCTV cameras, etc.) and processing power, there is a real possibility that privacy may become an unattainable goal unless technological and societal steps are taken to allow the citizens to regain control of their personal information and activities.   The ITN PriMa aims at training the next generation of researchers and technologists who have an all-round understanding of the multidisciplinary nature of the issues involved and who can contribute to the development of solutions that address this important societal challenge. PriMa will bring together Europe-wide complementary academic and industrial expertise to investigate these issues and provide a structure and environment to effectively facilitate training.  The proposed ITN will cover the technological issues regarding privacy protection for biometric technologies as well as the related ethical, legal and psychological issues.   The ITN will comprise academic and industrial partners, as well as an external advisory board. The academic partners from different European states will each run inter-related PhD programs requiring their ITN Early-Stage Researchers (ESR) to visit and work on their project at other partner universities, as well as at industrial partners
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Preclinical Protocols For Image-Guided Surgery' (2007-2013) under Seventh Framework.

assistant: **Objectives**

This project aims to build upon current developments in molecular imaging by developing a camera system and a tumour margin marker to be used in a first-in-human-trail. Molecular in vivo imaging is a fertile area which harbours a mix of expertise, state-of-art equipment and many different disciplines and inter-sector work environments. It is hoped that in the future it will be implemented as the fourth clinical modality in conjunction with the three already established clinical imaging techniques of magnetic resonance imaging (MRI), x-ray computed tomography (CT) and positron emission tomography (PET). The proposed project seeks to demonstrate that ZW800-1 (a novel zwitterionic Near Infra-Red Fluorescence (NIRF) dye), when conjugated onto a cRGD peptide, can be used to identify a minimum tumour margin distance during intra-operative image-guided surgery. These will be optimized to be used with clinical hand-held camera systems ArtemisTM, mini-FLARETM and MSOTTM . The overall aim is to aid the surgeon to visibly demarcate tumour from healthy tissue so that a complete image-guided surgical solution to cancer can be of benefit to patients and the healthcare system.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Advanced Cryptography for the Quantum Age' (ACQUA) targeting Horizon Europe.

assistant: **Abstract**

Project ACQUA brings together two of the most important trends in modern cryptographic study, with the aim of maximizing their combined benefit. One is the emergence of quantum computing as a realistic computational model, andthe other is the accelerated development of advanced cryptographic tools for the remote processing and control of private data.As we aspire to a world where quantum computing is prevalent, it is necessary to prepare the proper cryptographic tools for users to utilize their data in such a world. This includes protection against quantum attackers (known as post-quantum security), ways for classical users to securely maintain and process data stored on a remote quantum device, and methods to utilize quantum powers to exceed classically achievable capabilities. Recent developments in quantum cryptographic research gave us a glimpse of the possibilities that such a world holds, but they are still few and far between. We are still far from understanding even the theoretical possibilities and limitations. Project ACQUA is a concentrated effort, drawing from the theory of quantum computing and from the theory of cryptography, towards establishing advanced cryptography in a quantum world as a viable construct and unleashing its full potential.The project objectives consist of studying the effect of quantum computing on the foundations of cryptography, constructing relevant classical building blocks, and developing new quantum-cryptographic tools that are needed for an advanced quantum-cryptographic future.


**Keywords:** Theoretical Cryptography, Quantum Computing, Foundations of Cryptography
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Network Multiple-Input Multiple-Output for Advanced Wireless Systems' (NETMIMO).

assistant: **Concept**

Over the last two decades, the progressive introduction of advanced techniques (forward error correction, power control, link adaptation, incremental redundancy, etc) and the massive increases in processing power have taken wireless cellular systems to the point where links are operating close to their capacity and frequency reuse patterns are becoming universal. At this juncture, cellular systems have become limited, first and foremost, by their own interference. It is becoming increasingly clear that major new improvements in spectral efficiency will have to entail addressing such intercell interference. Traditionally, a user is assigned to a cell and it then communicates with that cell site while causing interference to all other sites in the system. The premise of NetMIMO is that, in the uplink specifically, intercell interference is merely a superposition of signals that were intended for other cell sites, i.e., signals that happen to have been collected at the wrong place. If these signals could be properly classified and routed, they would in fact cease to be interference and become useful in the detection of the information they bear. (A dual observation can be made about the downlink.) This insight naturally leads to the conclusion that, ultimately, the goal should be to serve all users through all the sites within their range of influence. While challenging, this is theoretically possible by virtue of the fact that the cell sites are connected by a powerful backbone network. This ambitious idea leverages the almost unlimited bandwidth available in optical wireline networks to transcend the burden of wireless intercell interference. In the NetMIMO framework then, the notion of a cell gets blurred once users are no longer assigned to specific sites. Ultimately,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Plasticity and formation of lasting memories in health and disease. Genetic modeling of key regulators in adult and aging mammals and in neurodegenerative disease' under Seventh Framework.

assistant: **Concept**

When an adult mammal acquires new skills and new knowledge, the degree to which transition will occur from temporary to permanent memories of such events is governed by factors such as emotional weight and importance of the experiences for survival. To execute the necessary structural synaptic reorganisations needed to permanently embed novel memories in the brain, a complex and precisely orchestrated molecular machinery is activated. We have found that rapid down-regulation of Nogo receptor 1 (NgR1) is one key element needed to allow permanent memories to form. Thus, our MemoFlex mice, with inducible overexpression of NgR1 in forebrain neurons, are severely impaired with respect to the ability to form lasting memories. When transgenic NgR1 is turned off in these mice, the ability to form lasting memories is restored. Several other genes are also involved in the process of consolidation of memories, including prompt activity-driven upregulation of BDNF. Very recently, we have discovered that Lotus, a newly identified negative regulator of NgR1, is also upregulated by activity, thus providing additional efficacy to the process of causing nerve endings to become temporarily insensitive to Nogo when plasticity is needed. Based on our experience with neurotrophic factors and the Nogo signaling system, and using additional transgenic mouse models, including the mtDNA Mutator mouse with premature, yet typical aging, NgR1 KO mice and mice modeling neurodegenerative diseases (such as APPSwePSEN mice and our MitoPark mice to model aspects of Alzheimer’s and Parkinson’s disease, respectively) we will examine the formation of lasting normal and pathological (addiction, posttraumatic stress disorder) memories in adult and aging individuals with and without additional neurodegenerat
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Business innovation through qualifying and (re-)employing of deaf people' (2014-2020) targeting Horizon 2020.

assistant: **Abstract**

Created in 2004, the Austrian SME equalizent is presenting the Signs for Europe project to standardize its worldwide unique business model which deals with job-related education and (re-) employment of deaf people and to export it via Franchise to European SMEs.  Integration of disable people is a challenge for today's society. The EU has committed to address the integration of deaf people (as per the European Disability Strategy 2010-2020). However, education offers for deaf people in Europe are rare, focused on school and apprenticeships and often only of limited use. This generates social inequalities and poverty for people with disabilities, as well as social exclusion and isolation.  equalizent has developed Signs for Europe to address the above challenges. This social innovation project aims to standardize our worldwide unique business model, which include a deaf people-centred training approach that uses sign language to teach deaf basic skills as well as professional training. The result is that 70%+ of all course attendees found a long-term job.There are around 1 million deaf people in Europe . It is our goal to provide trainings for 6,5 % of all deaf people regardless of where they are located. A mix of ex-cathedra teaching and a special Webinar-Technology, developed by equalizent for the target group, can be used. Target users are to be 16+ students as well as adults, exploiting the lifelong training approach.Taking into account the figures above, Signs for Europe is intended to generate a turnover of 19,35M€ just for equalizent (774M€ turnover for all franchises), by the end of a 4-year period (2018-2021). The needed investment to unlock this opportunity is estimated at 2M€, generating a ROI of 3,35% and creating 10 new jobs within the company (while more th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Oral delivery of encapsulated RNA nanotherapeutics for targeted treatment of ileal Crohn's disease' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

Crohn’s disease is a non-communicable, global disease with an accelerating incidence (up to 23 per 100,000 persons/year) and annual health costs in excess of 5 billion euro in Europe. Despite advances in new immune modulators and biological treatment, up to 30% of patients become non-responders, highlighting the pressing need for novel, advanced therapies. GENEGUT will transform treatment of ileal Crohn’s disease (CD) by developing a first-in-class oral RNA-based therapy, tackling inflammation locally in the intestinal tissue, while avoiding systemic side effects. The success of mRNA covid vaccines demonstrated the potential of RNA-based therapies; the challenge is to extend this revolutionary therapeutic modality to non-communicable diseases where RNA delivery has not been achieved, such as ileal CD. Delivery of RNA will be enabled by a combination approach where novel biomaterials, including amphiphilic cyclodextrins and amino polyesters (both patented by partners), designed to overcome the barriers in the gastrointestinal tract will complex the RNA within nanoparticles (NPs). Our industry partner’s novel capsule technology will ensure site-specific release of the encapsulated NPs at the diseased ileum. The RNA-nanotherapeutics (siRNA and mRNA) will modulate gene expression locally in the ileum by targeting the clinically validated (JAK/STAT) pathway and two exploratory targets, Gremlin and Adrenomedullin. Proof-of-efficacy will be demonstrated in vivo and also in a 3D multi-cellular model of ileal CD using primary human cells. GENEGUT brings together 9 partners from 8 European countries covering the lifecycle from bench to bedside, creating a network of renowned researchers, expert clinical scientists, SMEs and larger pharma companies and a patient organisation. GENE
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Structure-function studies of the general transcription factor IIIC (TFIIIC)' (TFIIIC) targeting Horizon 2020.

assistant: **Abstract**

Transfer RNAs (tRNAs) act as adaptor molecules, decoding messenger RNA and delivering the correct amino acid to the growing peptide chain. Being instrumental in the cellular translation machinery, it is important to understand their synthesis mechanism. In eukaryotes, tRNA gene (tDNA) transcription begins with transcription factor IIIC (TFIIIC) bound to 2 gene-internal promoter elements, A- and B-box. This is followed by the recruitment of transcription factor IIIB and RNA polymerase III to form the transcription pre-initiation complex. In ‘TF3C_EM’, I will focus on the mechanism and molecular architecture of the very first step, i.e., TFIIIC binding to tDNA. TFIIIC is composed of two subcomplexes, τA and τB, that bind respectively to the A- and B-box, and are flexibly linked to accommodate varying lengths between their binding sites. Interestingly, TFIIIC has recently been termed as ‘guardian of the genome’ in light of its extra transcriptional roles, such as chromatin remodelling. This further highlights the importance of exploring its underlying structure. Using recombinantly purified TFIIIC, I will characterise the fully assembled TFIIIC complex and TFIIIC-tDNA interactions in vitro. To this end, an inter-disciplinary approach will be used, spanning complementing biophysical and structural techniques of single molecule FRET, cryo electron microscopy and X-ray crystallography.  Thus, in my project ‘TF3C_EM’, I will tackle 3 major objectives: (1) characterisation of the molecular architecture of TFIIIC, (2) understanding the tDNA recognition mechanism by TFIIIC and (3) understanding the dynamics between τA and τB. It will unravel the structure-function correlation of TFIIIC and pave the way for further understanding the transcription initiation by Pol III. At the same
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'GOVERNMENTAL POLICIES and PROGRAMMES for STRENGTHENING THE RELATION SHIP BETWEEN HIGHER EDUCATION INSTITUTIONS and THE NATIONAL ECONOMY' (1994-1998).

assistant: **Innovation**

Governmental policies and programmes for strengthening the relationship between higher education institutions and the economy The central research question is: What are the main factors that have determined the success or failure of recent governmental attempts at the national or supranational level to strengthen the relationship between the higher education institutions and the economy, nationally as well as internationally? The project is aimed at examining at the institutional level the effects of governmental attempts on the relationship between higher education institutions and the economy in eight countries. The theoretical framework to guide the national studies, the institutional case studies and the comparative analysis is based on theories and approaches derived from the neo-institutional, the resource dependence and the innovation literature, as well as the literature on governmental steering models and policy implementation. For examining comparatively the basic conceptualisations included in the framework three analytical categories are distinguished: the intensity of the market orientation of higher education institutions, the relevance of the society orientation of higher education curricula, and the level of the international orientation of the higher education institutions. The basic assumption is that governmental policies and programmes for strengthening the relationship between higher education and economy, in order to be successful should have an effect on higher education institutions in such a way that the market orientation of higher education will increase, the society orientation of curricula will grow, or the international orientation of universities and colleges will be enlarged. In other words, success and failure of governmental policies an