RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Developing an Oil Free Polypropyelene Diaphragm Pump for Agricultural Application', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Diaphragm pumps are used in the agricultural industry to drive boom sprayers used to disseminate agrochemicals. Diaphragm pumps use oil for lubrication and hydraulic moment. These pumps however have a short life span (≤1000 hours) making them unreliable. Furthermore, because the pumps use oil, once the diaphragm has ruptured the oil contaminates the boom sprayer causing an environmental hazard as oil is sprayed onto the soil, affecting moisture absorption and soil fertility. There is a need for a reliable pumping solution which eliminates this environmental hazard, allowing farmers to conform with sustainable agriculture legislation. Idromeccanica Bertolini Spa is a company founded in 1918 which delivers pump solutions. With over 100 years of experience the company is well poised to deliver the next stage in agricultural innovation. Bertolini has created the B90 oil free polypropylene diaphragm pump to address the challenges faced in the industry. The pump eliminates the environmental hazard of oil contamination as it doesn’t use oil. Furthermore, the pump is the first of its kind made of the highly resilient polypropylene, which makes it 100% compatible with the host of over 3000 agrochemicals currently on the market. In addition, the design of the diaphragm unit incorporates a membrane support system which extends the life of the diaphragm to 3000 hours making it more durable than the current pumps while employing additional anti-leakage double manifold system. The target users of the pump are commercial farmers and our product will be sold directly to spray manufacturers. Through the completion of the project we aim to replace our current oil using pumps with the B90 series providing farmers with a 300% increase in life span and 0% chance of contamination. This allow
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'A Modular Earth System Model Emulator for Regional eXtremes' under Horizon 2020.

assistant: **Concept**

Climate extremes count among the most impactful consequences of climate change, also under low-emissions scenarios consistent with the aims of the Paris agreement. However, they are not factored in the derivation of emissions scenarios informing international policy options in reports from the Intergovernmental Panel on Climate Change (IPCC). Indeed, the Integrated Assessment Models (IAMs) underlying the development of these emissions scenarios only consider changes in mean climate when evaluating options for e.g. changes in agricultural production, biofuel production, afforestation or other land use changes.                                                                                                                              In the MESMER-X project, we will address this shortcoming by developing an operational Earth System Model (ESM) emulator providing climate extremes projections under different emissions and land use scenarios at negligible computational cost. This will allow for the first time a full interactive coupling between IAMs and climate scenarios. The MESMER-X emulator will be made open source and broadly available to scientists, policy-makers and society. The MESMER-X project will provide a disruptive innovation enabling the identification of realistic and resilient options for regional land use development consistent with a net-zero CO2 emissions future, with a focus on the European continent. The results of the MESMER-X project will be of high societal benefit for informing policy development consistent with the Paris agreement on European and global scale, including the European Green Deal


**Keywords:** Climate extremes, climate change, Earth System Models, emulators, droughts, heatwaves, mitigation scenarios, impacts
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Discovery of a new class of bioactive compounds:bacterial conjugation inhibitors', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

Combating bacteria with antibiotics directly cannot be effective in the long run because bacteria acquire antibiotic resistance (AR) genes easily from surrounding pools of resistant bacteria. Thus, an appropriate long-term public health objective would be to fight bacteria AND the mechanisms of AR acquisition with coordinated strategy. Acquisition of AR genes occurs primarily by the mechanism of bacterial conjugation. Preventing conjugation should markedly limit the dissemination of AR. This project's primary aim is to devise the most effective strategy to inhibit conjugation in or around the bacterial targets where AR is undesirable. For this purpose, we will isolate and characterize broad range conjugation inhibitors, test them in four model environments, and improve them by rational design. Administration of an antibiotic together with, or preceded by, administration of a conjugation inhibitor should prevent AR acquisition
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Molecular basis of histone acetyltransferase-mediated transcriptional activation' in the context of a Fourth Framework call.

assistant: **Objectives**

Research objectives and content The in vivo compaction of eukaryotic DNA with histones is a formidable barrier to chromatin transcription. Increased histone acetylation is linked to chromatin-associated gene activation, but the molecular mechanism underlying this relationship is still largely unknown. The important discovery that CBP protein has histone acetyltransferase activity which contributes to acetylation, offers new approaches to this question. CBP acts as a co-activator of the E2F1 transcription factor. My project aims at investigating the relevance of the CBP acetylase activity for E2F1-mediated transcriptional activation as well as the mechanism involved in this process. This study should help to understand the molecular basis of how histone acetylation is linked to transcription and should factor significantly into understanding of gene expression from natural chromatin templates. Training content (objective. benefit and expected impact) A main objective of the requested training is to greatly improve my scientific knowledge and technical skill in my own research field. Concretely, I expect to learn a novel technique developed and currently only mastered by the host laboratory. I also expect to benefit from the high-profile research of the host group which contributes regularly to important new findings and is at the forefront of my own scientific area.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Model Invariants in Algebraic Statistics', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

The goal of this research project is to develop new methods for data analysis based on algebraic statistics, demonstrate their effectiveness on real data problems, and make them available to the public as software packages.Three algebraic model invariants are central to this action: the maximum likelihood (ML) degree, the Euclidean distance (ED) degree, and the polar degree. Recently developed in theoretical research, these invariants promise to unlock new algebraic methods for data analysis. This action will realize this vision, expand the underlying theoretical foundations as needed, and produce statistical tools fit for use by practitioners.The expected impact of this research is fourfold. First, the obtained results will ground the latest theoretical advances in real applications, improving the algebraic statistics community's sense of what is possible and directing future research. Second, they will generate new mathematically interesting results tailored to the data applications of the project. Third, they will produce novel insights about complicated data problems with an algebraic structure, strengthening the case for algebra and geometry in data analysis. Fourth, the easily accessible software produced during this action will introduce algebraic techniques to the data analysis toolkits of data practitioners and domain experts.


**Keywords:** algebraic statistics, maximum likelihood degree, Euclidean distance degree, Wasserstein distance, monodromy, polynomial optimization, polynomial neural networks, algebraic statistical models
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Pushing dynamic and ubiquitous interaction between services Leveraged in the Future Internet by ApplYing complex event processing' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

The goal of PLAY is to develop and validate an elastic and reliable federated SOA architecture for dynamic and complex, event-driven interaction in large highly distributed and heterogeneous service systems. Such architecture will enable exchange of contextual information between heterogeneous services, providing the possibilities to optimize/personalize the execution of them, resulting in the so called situational-driven adaptivity.The main outcome will be a FOT (federated – open – trusted) Platform for event-driven interaction between services, that scales at the Internet level based on the proposed architecture and that addresses Quality of Service (QoS) requirements. The platform consists of:- Federated middleware layer: a peer-to-peer overlay network combined with a publish/subscribe mechanism, that has the task to collect events coming from the heterogeneous and distributed services,- Distributed complex event processor: an elastic, distributed computing cloud based engine for complex processing/combining of events coming from different services in order to detect interesting situations a service should react on- Situational-aware business adapter: a recommender engine for proposing adaptation and changes in running business processes and services in a non-predefined (ad-hoc) way, by ensuring the consistency of the whole instanceThe system will be tested in two use cases: crisis management and telecom industry, showing the advantages of such an architecture for Future Internet. Indeed, PLAY aims to revolutionize the Future Internet by making it situational-aware, which leads to the event-aware services that are able to proactively adapt themselves to the changes in the environment.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Standardization of biocompatibility testing of dental materials with emphasis on practical relevance' demonstrating excellence, impact and implementation quality for a Fourth Framework call.

assistant: **Abstract**

Dental materials including amalgams are currently disputed in the EU market because of their possible deleterious effects. Although cytotoxicity and further risks have been identified, current tests for cytotoxicity and biocompatibility have either not been performed or have not demonstrated these deleterious effects or systemic influences. This actual state is mirrored in the standardization of medical devices that are intended to support the directives on Active Implantable Devices and Medical Devices. Standards that cover the whole assessment are on product safety and performance from physical and chemical testing, biological and clinical evaluation to additional standards regarding quality assurance and risk analyses. The standards address both product oriented aspects and aspects such as sterilization, biocompatibility and clinical evaluation. The latter standards have the inherent characteristic of a lack of acceptance criteria. The uncertainty introduced by these standards must be compensated through risk analyses. The standards are based on conformity of data, but their subsequent assessment by notified bodies can not consistently guarantee the products to be safe and performing well. This is caused by the fact that the confirmation testing results of physical and chemical testing as well as the results of the biological and clinical evaluation are not adequate. Integrated requirement profiles and methodologies (model systems) are still absent. The major goal of this project is to offer such an integrated approach based on an assessment of the biocompatibility of available dental materials in contact with body fluids and tissue materials with special regard to their chemical and physical performance and their biological and clinical reliability. This will lead t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Promotional literature for EC funded oil & gas projects' in the context of a Fifth Framework call.

assistant: **Objectives**

The primary aim of the maxibrochures is to disseminate information on European oil and gas projects in a specific technological area, regardless of whether they have been funded by the EC. Three separate brochures will be produced on the following topics: deepwater technologies; exploration and production; and environmental technologies. The aim is twofold. Firstly, to make oil companies aware of new technologies that are approaching market readiness and that could provide solutions to their technological problems. Secondly, to make technology suppliers (particularly SMEs and research establishments) aware of developments that may be appropriate to a product that they are either developing or wish to be involved in.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Surface active sites and emission control catalysis', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

There is a special need at the European level to promote the training of young researchers in the areas covered by our proposed project. The reasons may be summarized as follows; the YRs will(1) learn about the functionality of modern catalyst materials and gain experience in working with these extremely important materials, and(2) learn about the modern surface analytical techniques (experimental as well as computational/ theoretical) that underpin much of the research and development in today's high technology industries. The training of young European researchers is the major aim of this Network. Each YR will get exposed to several different techniques (experimental and/or theoretical), in a few different laboratories, including at least one industry. The Network will contribute to the training of 18-16 young researchers for a total of 252 months.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Structure determination and redesign of enzymes active in the synthesis and hydrolysis of alpha-glucans for creation of novel specificities' (1994-1998) targeting Fourth Framework.

assistant: **Abstract**

This concerted effort by academic and industrial laboratories aims at improved understanding of structure-function relationships in enzymes synthesizing or degrading commercially valuable alpha-glucans. The goals are to tailor-make specificities i) in glucosyltransferases utilising sucrose for production of new prebiotic oligo- and poly-alpha-glucans to be applied in cosmetics, food, and feeds by BioEurope (Partner and SME expert in enzymic sugar synthesis) and ii) in hydrolases with novel or improved activities specific for alpha-1,4 and 1,6-bonds in starch, and branched, linear or cyclic oligosaccharides, thus addressing a need for multi-specific amylases, an ambitious target crucial in efficient starch utilization. To develop engineered hydrolases we collaborate with Carlsberg Research Laboratory on transgenic plants and Consortortium fur elektrochemische Industrie on enzymic environment- friendly industrial waste cleaning and sugar synthesis. Scientifically, the project is an integrated, multi-disciplinary approach, combining 3D structure determination, design and production of enzyme variants. The target enzymes bacterial glucosyltransferases, barley alpha-amylase and limit dextrinase, and bacterial cyclodextrinase are unified by two properties, i) a common catalytic alpha/beta-barrel domain, which we discovered in glucosyltransferases in a novel circularly permuted form and ii) structurally related substrates and products. We will provide evidence on enzyme-substrate interactions that describe new specificities at the atomic level and enable development of designer molecules by rational protein engineering. The project conforms to the area 6. Structural Biology, 6.1 Structure-function relationship with emphasis an development of biomolecules with desired functions
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'ADVANCED COPPER-BRASS RADIATORS FOR THE CARS AND COMMERCIAL VEHICLES OF TOMORROW' to be submitted under Fourth Framework.

assistant: **Abstract**

The main objective of the project is to adapt the results of recent research on the laser welding of thin-wall brass tubes, the development of a lead-free brazing alloy, and new structural alloys, to produce car and commercial vehicle radiators made of copper and brass. The technologies to be utilized offer both lower manufacturing costs and better in-service performance coupled with environmental benefits through improved recyclability. At least 50 new radiator assemblies will be constructed.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Insight into the Symbiotic Chemical Communication of Algae and Bacteria: Thallusin and Dedicated Analogues' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Thallusin was the first compound identified to induce thallus differentiation in macroalgae. This intriguing chemical mediator is produced by bacteria that socialize with algae in their natural habitat. Thallusin exemplifies a fundamental symbiotic chemical communication between macroalgae and epiphytic bacteria in the marine environment. However, its general impact on the underlying microbial communities and its chemical mode-of-action remains to be clarified. Therefore we propose a multifaceted research program to study the morphogenesis-inducing mechanism of algae by chemical morphogen. The proposed project will focus at four different objectives. 1) methodology development (heteroarylative/cyclization cascade), that allows the efficient and concise synthesis of thallusin. This will be achieved by ligand directed transition metal catalysis based on good literature precedent. The first objective is scheduled to be completed in first six month of the project. 2) development of novel, concise, scalable, and efficient asymmetric synthesis of (‒)-thallusin and its analogues. This will be accomplished by enantioselective polyene cyclization and heteroarylative/cyclization cascade as key steps. The second objective is scheduled to be completed from months 6-12 and 17-20.  3) structure-activity- relationships studies and 4) understanding the mode-of-action of thallusin in algae.  The objective 3 and 4 will be completed in collaborations. The labeled tool compounds and dye conjugates will be synthesized from promising candidates that will allow tracing the metabolism and degradation of thallusin in algae. The 3 and 4 objective is scheduled to be completed from 9-24 months. The results that will be obtained during the course of our research will have the potential capacity to