RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Recycling pilot plant facilities for advanced deinking, recycling and chemical treatments of recovered papers' in the context of a Fifth Framework call.

assistant: **Objectives**

CTP Recycling Pilot Plant simulates, with a strict control of the recovered papers used, the main treatments implemented in deinking and recycling plants, separately in successive sequences, or in continuous operating conditions and with a closed water system. The pilot is a very flexible tool. Its configuration is easily adapted to each type of trial by only changing the connection between the different devices. The range of equipment available allows processing all grades of recovered papers, to apply physical and chemical treatments in conventional or unconventional conditions and always in a full safety environment. The main devices that can be interconnected are the following: low and medium consistency pulper, coarse and fine screening, cleaning, flotation, oxidative and reductive bleaching, low and high-speed hot dispersion. Such equipment allows for example to perform two deinking loops with water recirculation. The heterogeneity of raw materials, processed in deinking plants, is a well-known source of quality variation of the produced pulp. On the pilot plant, the purposely selected low production capacity offers the advantage to process raw materials well defined. As well, for some studies, it offers also the possibility to process industrial recovered raw materials after their sorting (household or office collected papers). These conditions allow high accuracy results. For any additional information and (or) for access to this research infrastructures, please contact Benjamin Fabry (Benjamin.Fabry@ctp.inpg.fr)Application:People interested in participating in this programme should contact Dr. Benjamin Fabry (e_mail: Benjamin.Fabry@ctp.inpg.fr, Tel: +33-4-76154088, mail address: Centre Technique du Papier, BP 251, 38044 Grenoble Cedex 9 - France) to get the app
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'SMART-AML: Shaping Marrow Adiposity to Redefine Treatment in Acute Myeloid Leukemia' to be submitted under Horizon Europe.

assistant: **Abstract**

Acute Myeloid Leukemia (AML) is an aggressive hematologic malignancy characterized by the uncontrolled proliferation of myeloid cells, which hijack the bone marrow (BM) and compromise its physiological functions. AML prognosis remains poor, with <10% of patients above 60 years old surviving after 5-years. Recent discoveries have revealed the key role of BM microenvironment in harboring and protecting leukemic stem cells from chemotherapy, contributing to AML relapse. Therefore, targeting the hijacked BM niche and transforming it into a “tumor-inhospitable” microenvironment represents a promising therapeutic strategy. In adults, bone marrow adipose tissue (BMAT) is the predominant component of the BM microenvironment, making it an appealing target. However, the role of BMAT in AML development, drug resistance and survival is still controversial.With SMART-AML, I aim at identifying AML cells-related changes within the BMAT/BM microenvironment, to introduce BMAT manipulation as therapeutic strategy to sensitize leukemic cells to chemotherapy. To achieve this goal, I will exploit state-of-the-art bioprinting technologies to engineer a perfusable, humanized bone/BMAT 3D biomimetic microenvironment. Patient-derived AML cells will be cultured within the engineered platform to characterize the AML-induced BMAT changes in a controlled environment, with limited variables. Finally, BMAT will be manipulated (i.e. expanded or reduced), to determine the potential of this therapeutic approach on enhancing the efficacy of chemotherapy on leukemic stem cells and reducing the chance of relapse. This project will prepare me to become a tenured scholar, strengthening my academic profile and enabling me to establish myself as an independent principal investigator with a research line on adv
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'MEIOtic inSIGHT: Deciphering the engine of heredity' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Meiosis is an essential stage in the life cycle of sexually-reproducing organisms. Indeed, meiosis is the specialized cell division that reduces the number of chromosomes from two sets in the parent to one set in gametes, while fertilization restores the original chromosome number. Meiosis is also the stage of development when genetic recombination occurs, thus being the heart of Mendelian heredity. Increasing our knowledge on meiotic mechanisms, in addition to its intrinsic interest, may have also important implications for agriculture and medicine.In the last decade Arabidopsis emerged as one of the prominent models in the field of meiosis. Indeed, the meiotic field benefits greatly from a multi-model approach with several kingdoms represented, highlighting both conserved mechanisms and variation around the theme. Arabidopsis did not emerge only as a representative of its phylum, but is also a very good model to study meiosis in general, notably because of the possibility of large scale genetic studies and the availability of large mutant collections and wide range of molecular and cytological tools. In this project we aim to use original approaches to decipher much further meiotic mechanisms, by isolating a large number of novel genes and characterizing their functions in an integrated manner. To identify new meiotic functions, we will use innovative genetic approaches. The first work package is based on a new suppressor screen strategy, taking advantage of a unique and favourable situation in Arabidopsis. The second is an unprecedented screen that exploits the fact that we can now synthesize haploids in a higher eukaryote. The third work package aims to fully exploit the available transcriptome data. In the fourth work package we will use these new genes to deeply d
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Challenging The Limits Of Molecular Quantum Interference Effects' to be submitted under Horizon 2020.

assistant: **Abstract**

Over the last ten years, there has been a growing interest in quantum interference effects observed in molecules. Remarkably, given their fragility in mesoscopic physics, molecular quantum interference effects can be readily observed at room temperature in solution. This robustness comes from the extremely small size of the molecular components (1-2nm) and thereby the small dimensions over which phase coherence is required.   The aim of this project is to challenge the limits of molecular quantum interference effects delivering clear predictions of how to realise these effects in three challenge areas.  1. Beyond single molecules: intermolecular interference effects. This work package will investigate interference effects between molecules and in monolayers to find systems where intermolecular interference effects emerge with a long-term view to materials.  2. Beyond classical electronics: Quantum gates  Given that interference effects are an indication of phase coherence being maintained across the molecule, we should be able to exploit the quantum nature of the system for more than simply suppressing current. Proposals exist in the literature for realising a quantum computer through scattering, so this work package will investigate use the interference effects in molecules to suggest candidate systems for this type of quantum computer. 3. Beyond electron transport: Controlling vibrational energy redistribution  This work package will focus on how to use interference effects to control vibrational energy redistribution within single molecules with an aim of using this to modulate product ratios in organic reactions.  This project takes ideas that have come out of molecular electronics and tests the scope of their application in three neighbouring areas: supramolecular
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Supporting Teams in Mass Casualty Incident Management:  Empirical and Analytic Research for Optimizing Augmentative Technology - Design Methodologies and Tools' (2007-2013), addressing dissemination and exploitation.

assistant: **Impact**

There is an increase in mass casualty incidents and disasters resulting from nature disasters (e.g., super-storms, forest fires, earth-quacks and tsunamis, floods, etc.), accidents (oil spills, industry-related explosions, or train derailments, etc.), or terror attacks (e.g., 9-11, the London and Madrid bombing, etc.). Managing such incidents requires the well-coordinated rapid response of multi-agency and multi-professional teams (e.g., police, fire-fighters, emergency medical services, hazardous materials professionals, etc., from various local, national, and international agencies). The command and control (C2) of such incidents requires tight coordination among all involved agencies and teams such that each does their job and all together resolve the situation with minimal damage to lives and property.  Effective C2 requires all to have timely and reliable information to be aware of the situation at all times and understand it. However, adequate information flow can breakdown during information gathering and transfer within and across teams and agencies. This can in turn degrade situational awareness and coordination, and result in poorer incident management. There is a need to understand better the factors influencing information flow and situational awareness within and across teams in mass casualty incident management in order to develop and assess solutions that can facilitate the incident management. The goal of this proposed project is to understand and improve teamwork, in general, and information flow and shared situational awareness, in particular, in mass casualty incident management.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Aiding Antibiotic Development with Deep Analysis of Resistance Evolution' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

The inappropriate use of antibiotics has rapidly accelerated antibiotic resistance evolution in pathogens, rendering several existing antibiotics ineffective. However, many pharmaceutical companies have discontinued their antibiotic research programs. This is foremost due to the rapid spread of multi-drug resistant bacteria, which makes the commercial success of new antimicrobial drugs unpredictable. Antibiotic developers do not have a toolset to appropriately test antibiotic candidates for resistance evolution. Specifically, in the early phase of drug development, researchers typically identify numerous lead molecules with antimicrobial activities. It would be imperative to estimate the rate of resistance evolution at this early stage of development to all lead candidates in order to choose those that are the least prone to resistance evolution. The applicant and his team developed a technology, they term DIvERGE. It enables the exploration of resistance in a manner that is more comprehensive and effective than any other currently used approach. In a nutshell, DIvERGE finds resistance mutations in antibiotic resistance genes at an unprecedentedly comprehensive manner . DIvERGE offers a unique opportunity for pharmaceutical companies to identify antimicrobial agents with potentially longer clinical efficacy at an early stage of drug development. Thus, the goal is simple and bold – to identify antibiotics that are less prone to resistance development. Here the team aims to commercialise the technology.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Quasigroups, loops and related binary systems on algebraic manifolds' (2002-2006) under Sixth Framework.

assistant: **Objectives**

The concept of quasigroups is the non- associative generalization of the concept of groups. Since the 1930's, different categories (finite, topological, analytic) of quasigroups were intensively studied. In this project, we intend to investigate algebraic quasigroups and related geometric and group theoretical structures. The adjective algebraic is meant in the sense of algebraic geometry, that is, we assume that the underlying set Q of the quasigroup is an algebraic variety and the multiplication and its in verses are regular morphisms for Q×Q to Q.In our investigations, we will concentrate on the following problems: Factors of algebraic quasigroups; algebraic quasigroups and algebraic transformation groups; non regular algebraic quasigroups; the geometry of algebraic quasigroups. Our main tool is to collect information on the transformation groups generated by left and right multiplications of the quasigroup or special symmetries of the associated 3-net.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Aircraft 3rd Generation MDO for Innovative Collaboration of Heterogeneous Teams of Experts'.

assistant: **Concept**

AGILE targets multidisciplinary optimization using distributed analysis frameworks. The involvement of many disciplinary analyses ranging up to high levels of fidelity and agile workflow management are considered to be state-of-the-art and starting point for AGILE. Advanced optimization techniques and strategies will be developed in order to exploit available computing systems and to gain faster convergence to optimal solutions. Surrogates, decomposition, robust design and uncertainties, global-local optimization, mixed fidelity optimization and system-of-system optimization are central fields of research.Operating the coupled numerical system and interpreting the high fidelity results requires collaboration of heterogeneous specialists. Techniques for collaboration are the second scientific objective of AGILE using the research on optimization techniques as use case. The interactions between humans and the interactions of the design team with the numerical system both are investigated.Knowledge-enabled information technologies will be developed in order to support the collaboration process constituting the third, outer-most layer of the nested research concept. Novel technologies are iteratively implemented, tested and enhanced. Use cases are realistic overall aircraft design tasks for conventional, strut-braced, box-wing and BWB configurations.The project is set up to proof a speed up of 40% for solving realistic MDO problems compared to today’s state-of-the-art.The resulting technologies will be made available; amongst others via an Open MDO Test Suite.Reduced development costs and reduced time to market will enable a more agile way of collaboration and joint development and experimenting on innovative products. AGILE pronounces the collaboration of SME, RES and HES
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Hunger Bonds: Food Banks, Families and the Feeding of Poverty' (HUNG), addressing dissemination and exploitation.

assistant: **Impact**

In the United Kingdom food banks are increasingly required to alleviate hunger and food insecurity. In Greater Manchester (GM) alone, the GM Poverty Alliance mapped 171 emergency food providers. While the renewed interest of social scientists in the topic has produced an abundance of scientific literature, there remains a lack of knowledge on the webs of influence, support, conflict and interdependence between families experiencing food poverty and the emergency food providers. Project HUNG, by embracing a relational approach, focuses on the space of relations occupied by actors and institutions engaged with one another. Thereby, it proposes a relational object of analysis: not food poverty or food banks per se, but rather the interactions and transactions involved in the process of charitable supply and food demand.The project, based on the GM metropolitan county, makes use of quantitative analysis and ethnography of the everyday life to throw light on the ""hunger bonds"" connecting emergency providers and their users. On the one side, by gathering original survey data on food banks and their users, it provides a descriptive analysis on the determinants of food bank use through a dataset suitable for multilevel modelling (individuals nested in food banks). On the other side, it offers an in-depth ethnography of the daily life of a small sample of families that frequently rely on food banks by shadowing their meal choices for a prolonged period of time. By doing so, HUNG creates twofold added-value for the research community and for policy makers. Scholars interested in food inequalities will have access to a methodological toolkit, that could be used to extend research in other metropolitan domains. Simultaneously, by describing in detail the determinants of food bank
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Holistic Platform Design for Smart Buildings of the Future Internet', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

The main objective of HOBNET is to ease and maximize the use of FIRE platforms by multidisciplinary developers of Future Internet applications focused on automation and energy efficiency for smart/green buildings.<br/>The proposed research addresses algorithmic, networking and application development aspects of Future Internet systems of tiny embedded devices: a) an all IPv6/6LoWPAN infrastructure of buildings and how IPv6 can integrate heterogeneous technology (sensors, actuators, mobile devices etc) b) 6lowApp and its standardization towards a new embedded application protocol for building automation c) novel algorithmic models and scalable solutions for energy efficiency and radiation-awareness, data dissemination, localization  and mobility d) rapid development and integration of building management applications e) support for the deployment and monitoring of resulting applications on FIRE test beds.<br/>Key research innovations will be experimentally validated at an integrated platform of a large scale smart building proof of concept application, in two buildings of a UN related foundation in Geneva and two existing FIRE test-beds. The buildings will act as source of research challenges for smart services like energy optimization, control access, safety, audio/video provision and automatic control. Developed algorithms and technology solutions will be tested via deploying large numbers of diverse smart devices at the buildings and FIRE test-beds. These tests will also provide real data traces towards accurate models. A repository of implemented algorithms and a multipurpose building automation demonstration for connecting with external activities will be provided.<br/>We take a holistic approach addressing critical aspects at different layers (networks, algorithms,