RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Design of Fiscal and Monetary Policies: Central Bank Objectives and Public Debt Management' (MONFISCPOL).

assistant: **Innovation**

The goal of the project is to develop economic models for the design of fiscal and monetary policies to tackle the current economic crisis – the primary objective of the European Commission Work programme for 2013. The first part of the project will develop a framework to determine what should be the primary objectives of central banks. The main goal is to understand if central banks should only focus on maintaining price stability – the conventional wisdom in among academics and practitioners–  or  should instead devote more and more attention to other objectives, like reducing unemployment and stabilizing the financial markets. The results will be particularly relevant for current debates at the European Level about the goals of the European Central Bank. The second part of the project develops a framework for the management of the debt maturity structure to explain the existing relationship between debt holdings and interest rates paid by governments. The successful completion of the project will contribute to the current debate about the potential benefits from the adequate management of public debt, in terms of reduction of the costs of financing, that will ultimately translate into higher social welfare.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'BEyond Willpower: InterTemporal CHoice Improved through NudginG' (BEWITCHING).

assistant: **Innovation**

Many decisions involve intertemporal choice: a choice between options whose consequences occur at different points in time. For example, choosing whether or not to eat cake when you also want to lose weight this month. Remarkably, we often choose small immediate rewards (e.g. eat cake) over large future benefits (e.g. lose weight), despite different intentions. How can we become better at resisting temptations and align our behavior with our long-term intentions? ‘Nudging’, a concept from behavioral economics, appears a promising strategy: by designing choice contexts that exploit our cognitive biases, it gently guides us into making choices that are better for ourselves and society. One way to nudge intertemporal choice is by ‘framing’ the timing of the choice outcome in a certain way: e.g. we make more patient choices when future outcomes are described in terms of calendar dates (‘on May 1’) than in terms of corresponding delays (‘in 30 days’). However, two problems hamper the use of time framing in practice: we do not know how time framing works nor who is susceptible to it. If we do not address these problems, we will not understand our seemingly irrational choices and we will not be able to develop framing interventions that change behavior. To solve these problems, I will determine the mechanisms and individual determinants of time framing in intertemporal choice, using new computational models, functional MRI, and an online experiment. My working hypothesis is that time framing changes how we perceive time and that individual differences in time perception determine whether or not time framing changes behavior. The proposed research will provide scientists, policymakers, clinicians, and businesses with a deep understanding of how framing influences our choices. T
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'RAILWAY OPEN SYSTEM INTERCONNECTION NETWORK' demonstrating excellence, impact and implementation quality for a Fourth Framework call.

assistant: **Abstract**

ROSIN seeks to develop interconnection between equipment located inside a single railway vehicle or in different train vehicles, by means of a standard digital communication network. An important application will be inter-operation of coaches from different countries in cross-border international trains. Another will be inter-operation within vehicles to enable devices to be easily interchanged. It will also be possible to link on-board systems with ground control and signalling mechanisms via the network. All aspects of on-board networking are covered by this project geared to substantial improvement in rail performance and competitiveness.The ROSIN project addresses the problem of interconnection between equipment located inside a railway vehicle or in different vehicles of a train, by means of a standard digital communication network, so as to achieve the following main objectives:- interoperability at the train level, to allow inter-operation of coaches from different countries, especially for international trains performing cross border service- interoperability at the vehicle level, to allow easy interchangeability of devices- support to commissioning and maintenance phases and a general reduction in products life cycle cost- openness toward external systems, to link on board systems with ground control and signalling systems- performance improvement and introduction of new servicesThe ROSIN project aims at the validation of a complete open platform, that will be the base of a new generation of vehicles, consisting of an on-board network that is able to interconnect all various on-board systems and subsystems.Taking advantage of a 5 years effort to specify a standard train communication network (TCN), being carried out within the International Electrotechnical Com
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Dissemination of european strong motion data' under Fourth Framework.

assistant: **Concept**

There is a continual growing demand for safer equipment, buildings and systems under earthquake loading. However, at the same time financial constraints place emphasis on finding cost-effective ways to enhance earthquake safety and reduce liability. A basic problem in earthquake resistant design is the selection of ground motions generated by the design" earthquake. Near-source (strong) ground motions determine the forces endangering engineering structure. They also provide detailed information concerning the source mechanism and the propagation path of the seismic waves generated by the earthquake. Strong ground-motion records are therefore of major interest to both earth scientists and engineers, and an indispensable tool for establishing EUROCODE-8. There is then a clear need to present to the European community a dataset of wholly European high quality strong-motion data for use both in research and industry. This requires actual strong-motion time-histories and resulting response spectra and, equally importantly, reliable measurement (seismological) parameters. The proposed programme is aimed at collecting, processing, storing and making available via CD-ROM and the Internet a database and a databank concerning parameters of European shallow and intermediate depth earthquakes. This will include associated triaxial strong-motion acceleration records (more than 1000), both in uncorrected and corrected form, and corresponding response spectra. Database parameters will include event date, location, depth and size whilst information concerning individual records will include station location distance, peak accelerations, instrument type and location, and foundation (soil) type. In addition appropriate software will be provided allowing the user to search the database an
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Next Generation Gene Therapy for the Treatment of Chronic Myocardial Ischemia and Heart Failure' (HeartGenes).

assistant: **Innovation**

BACKGROUND: Therapeutic angiogenesis has great potential for the treatment of severe heart diseases. However, this requires novel approaches and development of new technology.ADVANCING STATE-OF-THE-ART: We will develop novel VEGF-B and VEGF-C-based gene therapy to treat refractory angina and heart failure (HF). VEGF-B and VEGF-C lead factors were selected from extensive pig studies where they showed the best benefits among all VEGFs, such as relative cardiac specificity, potent angiogenic and metabolic effects (VEGF-B) and lymphangiogenic activity (VEGF-C). Exogenous gene transfer and new endogenous gene activation technology will be developed.Key new technologies are riboswitch-regulated-AAV8 vectors, Super-Enhancer driven cell-type targeted gene expression, VEGF-B and VEGF-C designer mutants for better efficacy and activation of natural endogenous VEGF-B and VEGF-C expression with promoter binding shRNAs, circRNAs, CRISPR/mutantCas9-VP64-SAM gene activation technology and using a novel concept of the release of promoter pausing. Immunological concerns of AAV8 and usefulness of new synthetic dendrimer carriers will be addressed. HeartGenes utilizes optimized percutaneous intramyocardial and retrograde venous gene delivery in pig chronic ischemia and HF models, clinically relevant pig exercise test, and 15O-H2O and 18F-FDG PET/MRI imaging to detect treatment effects. Simultaneously, HeartGenes will take a realistic approach to clinical translation and starts intramyocardial vs retrograde venous riboswitch-AAV8-VEGF-B186 phase I trial in refractory angina as the first step to bring the best novel constructs and the most advanced functional and imaging endpoints developed in HeartGenes to clinical testing at the end of the project.SIGNIFICANCE: If successful, this approac
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Participatory Approaches to a New Ethical and Legal Framework for ICT' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Changes in the regulation of ICT research and innovation are opening up a new scenario. It is expected that stakeholders, policy makers, and end users adapt to them as soon as possible. This, however, might be hard, especially for SMEs. PANELFIT is firmly committed to facilitating this adaptation process by producing a set of editable, open access Guidelines, validated by two data protection agencies. Once produced, they will serve as operational standards able to reduce the ethical and legal issues posed by ICT technologies while promoting innovation and market growth, enabling high-quality job creation and ensuring an adequate level of privacy and security/cybersecurity. Furthermore, we will produce a complementary set of six outcomes to 1) suggest possible concrete improvements to the current regulatory and governance framework, both at the EU and the national level, 2) create mutual learning and support tools and to promote networking among stakeholders and policy makers and 3) increase the quantity and quality of the information available to policy makers, professionals, researchers, journalists and the public. All these outcomes will be produced by a co-creation process involving policy makers, stakeholders, and end-users. They will all participate in the creation of the main outcomes of the project through a range of engagement activities that includes workshops, public consultations, encounters, surveys, etc. This will be combined with a strong communication and dissemination strategy that includes numerous activities, such as webinars, MOOC courses, public debates, a constant use of a web site and social networks and the creation of a Platform for Mutual Learning, which is meant to become the reference forum for the discussion of the issues at stake even after
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'MINING THE GENOME OF P. FLUORESCENS F113 TO IMPROVE AGRICULTURAL AND BIOREMEDIATION APPLICATIONS. In silico genomics and functional genomics approaches to exploit Pseudomonas in biotechnology' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

Microorganisms from the fluorescent pseudomonads group are valuable in agriculture for plant-growth promotion and biocontrol of fungal pathogens and have environmental applications in soil decontamination or bioremediation. Previously, a European-funded project successfully improved decontamination capabilities of Pseudomonas fluorescens F113. More recently, sequencing of F113 genome has revealed regions encoding putative insecticidal proteins which could expand its biotechnological uses. The overall aim of this project is to gain a deeper understanding of the properties of P. fluorescens F113 and enhance its biotechnological potential. Functional genomics and bioinformatics approaches combined with traditional molecular microbiology techniques will be used to achieve the following objectives: • To understand F113 genomic characteristics through a bioinformatics genomic analysis and to identify genes to improve and expand its biotechnological applications. • To study the properties conferring ecological fitness by the analysis of the virulence factors that F113 possesses against invertebrate predators, in particular insects. • To study gene expression and regulation in order to devise in the future engineering of a strain better adapted to the environment and better suited for agricultural and environmental uses. This project fits within the thematic area of “Food, Agriculture and Fisheries, and Biotechnology” and will impart significant economic and social impact by developing key knowledge and tools towards sustainable agricultural practices and a cleaner environment. This proposal also fulfils the objectives of mobilization of technology, knowledge and researchers across the EU and will establish new collaborations between British and Spanish Universities.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Sixth Framework proposal for the project 'The role of the pH inside the Salmonella-containing vacuole on type-III secretion triggering and on bacterial intracellular multiplication'.

assistant: **Objectives**

Type-III secretion (T3S) systems allow Gram-negative pathogenic bacteria to reprogram eukaryotic host cells by injecting effector proteins through a eukaryotic membrane into their cytosol. Salmonella enterica are facultative intracellular enteropathogens t hat infect humans and animals, causing a wide range of diseases.Salmonella reside and replicate inside host cells in a membrane-bound compartments called Salmonella-containing vacuoles (SCVs), which use a unique trafficking pathway. The Salmonella pathogenicity island-2 (SPI-2) T3S system is required for intracellular bacterial replication. This indicates that SPI-2 effectors, delivered through the vacuolar membrane, act on intracellular trafficking to mediate the creation of a niche permissive for bacteri al multiplication.The SCVs acidifies to between pH 4.0-5.0, and in vitro SPI-2-mediated T3S is triggered by this pH range. This suggests that acidic pH might be the physiological stimulus for SPI-2-mediated T3S inside the SCV. In this project, we aim to characterize SPI-2 T3S triggering, understand its role in Salmonella pathogenesis, and gain deeper insights on the mechanisms employed by pathogens to modulate intracellular trafficking.We propose to screen and characterize the gene(s) required for in vitro SPI-2 T3S triggering; investigate the mode of action of the affected protein(s); determine if acidification triggers T3S inside the SCV; and study the influence of vacuolar pH on Salmonella intracellular trafficking and multiplication. We will use a wide genome screening method to study the mechanisms of virulence of a very important human and animal pathogen.The full understanding of the SPI-2 T3S triggering will open the possibility of developing specific drugs to combat Salmonella infections. Thus, this project
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'NGI Research Goes To Standardisation' in the context of a Horizon 2020 call.

assistant: **Objectives**

NGI vision is to re-imagine the Internet for the third millennium, which has to be an Internet of Human Values, resilient, trustworthy and sustainable. Blockchain and DLTs are promising technologies with enormous potential to develop a more human internet based on NGI Values, but these technologies face numerous challenges that could affect its full adoption.NGI-GO2S contributes to this vision by reinforcing the European Blockchain ecosystem and excellence in research by supporting 76 to 112 promising Bottom-up Projects [BuPs] able to develop and roll-out Advanced Blockchain Technologies [ABTs] aimed to close the scalability, interoperability and sustainability challenges.In order to get it, NGI-GO2S will leverage on Big Data Analytics technology -provided by INNEN, company specialised on advanced IT search solutions- to scout 1.000+ outstanding ‘Blockchain Talents’ and in FBC -the company specialised in building communities around innovative technologies- to attract and integrate outstanding researchers in the European Blockchain Ecosystem.An agile, transparent and flexible continuous 2-Stages Open Call scheme will select the best BuPs. We build on the experience that FBA -European leader in Financial Support to Third Parties- has on this field to make it simple and user-friendly, to allow committed ‘Blockchain Talents’ to focus on delivering solutions to important problems.Finally, NGI-GO2S will deliver a one-in-all Support Program for Standardization of ABTs that will increase the capability of BuPs by complementing their knowledge and skills with world class domain experts in fields, such as security and privacy, DLT technologies, standardisation or open commons business models. NLnet, the entity of reference in Internet domain at EU Level, will provide guidance and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Research and development of a personal flying system the fanman""' goes beyond current state-of-the-art under Fifth Framework.

assistant: **Innovation**

The Fanman is a new concept of machine, allowing the displacement of men in the air easily and at a reasonable cost. This new machine will be used at first by civil security companies which will be able to survey forest fires, manifestations, by private people for air leisure and in a mid term period as a private vehicle allowing people easy displacements in the air. The Fanman general specifications are the lifting of 100 kg, an autonomy of 1 hour, a consumption of generic fuel and a very reduced working noise. The aim of the research is to- increase the performance of the turbine by 15%,- increase an engine specific power by 30 %- study the transmission and vibrations- develop a new electronic control device. This project will be carried out by a consortium of 5 SMEs which will conduce the project with research centers and make the exploitation of the results by themselves.