RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Lasercom-on-chip for next generation, high-speed satellite constelation interconnectivity' under Horizon 2020.

assistant: **Concept**

The satellite market experiences a paradigm shift with the rise of satellite constellations that are changing the satellite volume launched from now on. Under increasing capacity requirements, primes admit that lasercom is required to connect their constellations at high speeds not possible with RF equipment. This is shaping a unique opportunity for the penetration of optical inter-satellite links (OISLs) into a market that will only grow. The deal for OISLs is clear; low cost, size, weight and power consumption (C-SWAP), but the current tools and methods used to make OISL systems are fundamentally incompatible with this requirement and the jump to satellite lasercom is a jump to higher complexity. ORIONAS aims to provide the technology that will disrupt the way lasercom systems are designed, built and tested and hit the right C-SWAP targets. ORIONAS invests in monolithic integration within European BICMOS and InP foundries for cost-effective access to high performance technologies. Using its photonics BICMOS integration platform, ORIONAS will squeeze lasercom transceivers into a few mm^2 demonstrating modulator/driver electronic-photonic IC (ePIC) being >2 orders of magnitude smaller than state-of-the-art space (SOTA) qualified modulators and receiver ePICs being 3 orders of magnitude smaller than conventional free space optics receivers used in current lasercom modems. ORIONAS will develop a Hi-rel packaging technology to deliver all-laser weldable, hermetic transceivers that will be 20 times faster and 16x times smaller than current SOTA lasercom systems and with power dissipation in the order of a few pJ/bit. Using InP integration ORIONAS will fabricate SOAs being 2 orders of magnitude smaller than current space qualified high power fiber amplifiers and >10x times m
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Wellbeing and Employability for Youths with Psychosocial Disabilities through Digital Technologies', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Psychosocial disability (PD) refers to ‘disabilities that arise from barriers to social participation experienced by people who have or who are perceived to have mental conditions or problems’ According to the World Health Organization, mental, neurological and substance use disorders (MNS) account for more than 10% of the global disease burden of disease and are responsible for 1 in 5 years lived with disability. The global loss of productivity on account of depression and anxiety is estimated to cost the global economy US$1 trillion each year. In low- and middle- income countries, more than 75% of people with MNS receive no treatment at all for their disorder. In Kenya, unmet need for mental health services (MHS) is worse in young persons compared to adults. Further, poverty and adversities are causes and consequences of poor mental health and persons with PD experience discrimination in mental health service, employment, and social life that affect wellbeing and life expectancy. Mental health services in Kenya are sparse and elude most persons with PD. Access to available MHS is limited by lack of information about where and how to access it, and discriminatory delivery of services. In recognition of the dire need for inclusive mental health services, a recent interagency Government of Kenya Taskforce on Mental Health in 2021  declared  mental ill-health in Kenyan society as a national public health emergency. Also, strengthening the Mental Health system is the fourth strategic objective of the Kenya Mental Health Action plan 2021-2025.   This project responds to this need (identified by GOK taskforce) and aligns with the WHO’s vision of a world where ‘all people achieve the highest standard of mental health and well-being’. The overall aim of this project is to deve
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Designing the Irresistible Circular Society' to be submitted under Horizon Europe.

assistant: **Abstract**

Designing an Irresistible Circular Society (DESIRE) aims to create an alternative way forward for the built environment supporting the EU mission of ‘100 climate-neutral and smart cities’. Against seemingly insurmountable challenges of climate change, biodiversity loss, and resource depletion we need to rethink our approach to finding solutions. Departing from architecture, design and art we will create an open learning environment with principles, methods and guidelines to support us in designing an irresistible circular society. We will present a DESIRE lighthouse demonstrator, built on insights and learnings from on-site demonstration activities taking place on sites in Denmark, Italy, Latvia, Slovenia, and The Netherlands, encompassing various themes and scales. By this, we will set the foundation for a school of thought and practice, and establish a scaling framework for widespread learning across the EU utilizing digital infrastructure, stakeholder involvement and empowerment across a partner community of European cities, youth organisations, NGOs, academia etc.   Our territorial sites form the core of DESIRE. Three themes have informed our choice of sites and partners. ‘Creating social and inclusive housing’ addresses the need for inclusive processes, ‘the power of we’, in circular transformation of social housing. ‘Reconciling cities with nature’ is about designing livable habitats and functional ecosystems from a multispecies perspective while rebalancing ‘land use’ to accommodate resource generation and biodiversity. ‘Transforming through symbiotic relationships’ focuses on how to optimize use of materials flow when rethinking urban landscapes in cities. In depts on-site demonstration activities will unfold in three Danish sites (an old asphalt factory in Herl
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'proactive monitoring of cancer as an alternative to surgery' to be submitted under Horizon 2020.

assistant: **Abstract**

From 2016 -2019, the “first” PRISAR consortium implemented the first Dutch RISE project of H2020 to investigate the use of imaging technologies and hybrid fluorescence/radionuclide probes for the surgical intervention of cancer. This PRISAR project provided a career-enabling human resource plethora of inter-disciplinary and inter-sectoral secondments, which resulted in the development, of not only a hybrid probe for image-guided surgery, but also a variety of tools and instruments. We now propose a new project, PRISAR2, to implement the next logical phase of this work, which is to clinically translate new and innovative monitoring technologies from industry. This will provide better patient selection and increase the surveillance window to allow for better treatment options over time and avoid surgery. This will involve developing new ‘watch and wait’ strategies to study the behaviour of the cancer so that any risks can be minimized. This would lead to a better clinical outcome and quality of life (QOL) for the patient and maximize the benefits of an active monitoring policy for both the patient and the healthcare system. When a patient is discovered to have cancer, one of the primary goals is to have the tumour removed by surgery. Here, however, we aim to (a) develop new monitoring technologies from industry so that the surveillance window can be increased to allow for better treatment options over time and to avoid surgery, (b) develop new ‘watch and wait’ strategies in order to study the behaviour of the cancer so that any risks to the patient can be minimised leading to a better clinical outcome and (c) train a new generation of preclinical and clinical scientists to be able to implement this new concept as standard of care and to maximise the benefits of an active
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Hybrid Imaging in the Catheterization Room'.

assistant: **Objectives**

Hybrid Imaging in the Catheterization Room In the previously-completed ERC CoG, we have developed a patented c-arm scanner (called IXSI) which can accomplish real-time hybrid image guidance in dynamic environments such as the intervention and the catheterization room. Thus far, we have evaluated IXSI for oncological purposes. But more recently, we have identified a new potential application in the field of interventional cardiology, in which hybrid imaging may help for determining the culprit vessel during the interventional procedure or directly evaluating the outcome of a treatment. In this ERC Proof of Concept, we will explore whether the new proposed application of IXSI is worth pursuing further. We will perform four tasks: i) we will investigate for which groups of cardiology patients or treatments IXSI may provide the greatest benefit and assess their market share, ii) we will evaluate the performance of IXSI for cardiology by developing custom-made testing devices, iii) we will investigate whether IXSI can be made more cost-effective for cardiology by making hardware modifications, and iv) by combining the information from the previous activities, we will develop a business case of IXSI specifically for cardiac interventions. Should it be demonstrated that IXSI can aid cardiac interventions, then we expect that our developed technology will be much quicker implemented in the clinic seeing that the proposed application field is massive and the incentive for commercialization would be greater (close to 1 million PCI procedures are performed per year in the US alone).
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Resolution Enhanced Microscopy for Medical Diagnostics' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Since the histopathological diagnosis of tumours is based on microscopy, it would be highly desirable to possess a microscopical technique allowing morphological investigation with a wide zoom range, high resolution and the implementation of multiplex staining. Thus, the goal of the REMEDI project is to explore the possibilites of novel light microscopy techniques, which overcome the diffraction limit of visible light and extend the range of observation to the molecular level of proteins in tumour cells and analyze their interaction and spatial distribution. This proposal aims at the use of single-molecule-microscopy of cancer tissue samples with ultra-high sensitivity, simplified handling and increased speed of analysis. This shall be accomplished by the development of a novel resolution-enhanced microscopy platform with an integrated novel CMOS camera and an adequate image acquistion and analysis software. The REMEDI platform will be validated with two relevant applications: diagnostic/experimental pathology of breast cancer and alterations of plasma membrane components of lymphoma cells.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Supramolecular assembly of Janus Carbon Nanotubes into functional 3D microparticles' to be submitted under Horizon 2020.

assistant: **Abstract**

The remarkable mechanical, electrical, thermal and optical properties of carbon nanotubes (CNTs) are only valid for individual particles, and are generally lost when bulk CNT materials are integrated in devices. The controlled manufacturing of macroscopic functional and high-performance CNT-materials, retaining the compelling properties of individual tubes, has hence become of paramount importance to allow their full exploitation within commercial products.With the Supra-CNT project we aim at tackling this compelling issue by performing an unprecedented sequential engineering of the architecture of CNT materials, from the nano-, to the micro- and macroscale level. Specifically, we intend to synthesise Janus amphiphilic CNTs, which will be able to self assemble into well-defined 3D microparticles following the instructions encoded in their pre-organised functionalisation. These structures will then be employed in large area self-assembly to form higher order macro-assemblies (i.e. colloidal crystals), achieving an unprecedented degree of hierarchisation and tailoring of the CNT material.By providing such controlled multiscale engineering, Supra-CNT will shed light on the structure-property relationships characterising CNT bulk materials. This knowledge will allow for the implementation of a property-conservative manufacturing of CNT-based materials, boosting their performance–to–cost ratio, and integration in a vast set of applications with high societal and industrial impact, such as high performance filters, catalysts, and energy storage devices.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'WASTE HEAT RECOVERY FROM POLLUTING FUELS WITH OPTIMIZED SO3 REMOVAL AND PREVENTION OF AEROSOL FORMATION'.

assistant: **Concept**

In addition to the classic FGD in Power plants, installation of an exchanger designed to condensate (gentle cooling) the vapors and aerosols of SO3 gases after the FGD itself. This improvement allows to reach a 90% rate of removal of SO3 instead of 20 to 30%. Aerosols are very prejudicial to environment. The design of the exchanger must be very special and is the heard of the project.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Bridging the gap: an evolutionary genomics approach to illuminate the prokaryote-to-eukaryote transition.' to be submitted under Horizon 2020.

assistant: **Abstract**

Eukarya – one of the three Domains of Life along with Archaea and Bacteria (i.e. prokaryotes) – include all complex multicellular life forms, as well as a colossal diversity of unicellular microorganisms. At the cellular level, the gap between prokaryotes and eukaryotes is immense, with the latter cell types displaying a large number of complex subcellular organelles and molecular systems. The evolutionary origin of these unique features, and thus of the eukaryotic cell itself, remains one of the most fascinating enigmas in modern biology. Although many eukaryotic-signature proteins (ESPs) are known to trace back to the last eukaryotic common ancestor, their deeper evolutionary origins remain unclear. The major goal of the current proposal is to illuminate the prokaryote to eukaryote transition by elucidating the origin and subsequent evolution of ESPs, as well as their order of emergence. We will focus on the ESPs of archaeal origin with an emphasis on the specific contribution of the newly discovered Lokiarchaeota lineages to the origin of the eukaryotic cell. In addition, we will aim to determine the placement the eukaryote lineage within the tree of Life and infer the age of the “first eukaryote”. Finally, we will use a novel phylogenomic approach to infer the gene content of the archaeal ancestors of eukaryotes by mapping the evolution of ESPs along the tree of Life. For this purpose, we will analyse entirely novel genomic data from several uncultivated Lokiarchaeota lineages, as well as novel sequence data from deep-branching key eukaryotes. This project will integrate approaches from distinct disciplines within life sciences and computational sciences (including molecular evolution, genomics/metagenomics and cell biology), with a strong emphasis on phylogenomics.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Dual-channel paper-based electroanalytical platform for multiple myeloma care'.

assistant: **Concept**

Multiple myeloma (MM) is an aggressive type of cancer of plasma cells where fast diagnosis and treatment monitoring is vital, especially given the overall low survival rate. Proteasome, a multi-catalytic complex essential in damaged protein degradation, has been recently established as a biomarker for MM, in which elevated levels have been observed in blood plasma of unhealthy individuals, as well as its impaired activity has been target for treatment alongside regular chemotherapy. PADMME addresses increasing contributions on proteasome electrochemical recognition and aims to develop novel interdisciplinary technologies translatable into POCT systems for MM care. For this, we propose the development of sensitive and selective dual-channel platforms comprising conductive polymeric fiber biosensors integrated on paper-based microfluidic supports to simultaneously detect quantity and specific activity of proteasome in blood plasma. Paper supports ensure disposability and ease of commercialization, whilst incorporation of microfluidic paths allows low sample volume requirements and in situ pre-treatment steps. Conductive polymeric fiber scaffolds provide increased signal resolution for the construction of biosensors, necessary for the recognition of low concentrations of the biomarker. Then, investigating proteasome at the dual-channel platform in drug-treated and untreated MM cell lines will demonstrate how changes in quantity and specific activity are specifically linked to the disease dynamics. The last step will comprise validation of the technology for analysis in blood plasma, technology able to improve overall monitoring of MM disease progression and therapeutic efficiency, crucial to overcome delays in treatment due to drug resistance complications. Training throug
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'DEVELOPMENT OF NANO-POROUS MATERIALS FOR THE PRODUCTION OF VACUUM INSULATION PANELS (VIPs)'.

assistant: **Objectives**

Vacuum insulation panels (VIPs) offer extremely high thermal resistances properties combined with small thickness that can enhance the energy efficiency of the insulating systems and provide savings in energy consumption. They are generally made with porous core materials wrapped, under vacuum, in airtight films. In the construction of VIP, core materials play a crucial role in thermal performance and mechanical properties of the insulation system. Commonly used core material is fumed silica with nanoporous structure. Core materials with higher porosity and smaller pore size have the greater ability to maintain lower thermal conductivity. However, high product costs are the main obstacle for a broader penetration of the VIPs technology into many applications like cold appliances and building insulations. The main objective of the proposal is to develop cost effective novel nanoporous core materials that can be used as core insulation filler in VIPs, which will help for the widespread usage of this technology for applications in cold appliances and/or building insulations. The nanoporous inorganic materials will be developed using triblock self-assembled polymers (Pluronic® F127) as structure directing compounds. Pluronic forms nano-size micelles and have polar OH end groups that when assembled as a surface can provide slightly negatively charged sites for nucleation of the inorganic phase. After the coating of the nano-size polymeric micelles with the inorganic phase, a porous structure will be obtained when the polymer is removed from the inorganic-polymer composite by calcination. Then, VIP prototypes will be produced with the developed porous core materials and thermal performance at the different vacuum levels will be measured. It is aimed to develop VIP with therma