RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Deciphering the interplay between stem cell differentiation and stem cell dynamics in branching morphogenesis' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

Tissue development requires the orchestration of stem cell differentiation and morphogenesis, a process that is conspicuously observed in mammary gland (MG) branching. The MG develops from an embryonic bud of mammary stem cells (MaSCs). Although these stem cells are initially bipotent, giving rise to the outer (basal) and inner (luminal) layers of the adult gland, they become lineage restricted very early in embryogenesis, at around the time of the onset of branching morphogenesis. The timing of lineage restriction coincides with the differential expression of cell polarity and cell adhesion transcripts. Branching morphogenesis then relies on differential cell division, as well as cell rearrangements and migration, but the mechanisms regulating this process in the embryo remain poorly understood. Based on these observations, we postulate that basal-biased and luminal-biased MaSCs have distinct molecular features during branching morphogenesis. We therefore propose to functionally link the signaling pathways involved in restriction of stem cell potency to the cellular dynamics that ensure branching. To this end, we will characterize the dynamic behaviour of individually labeled MaSCs during the growth of embryonic MG explants and assess their fate, creating a complete fate-behavior map of MG development. Through genetic manipulation, we will probe how cell adhesion, migration, and division impact on lineage specification and tissue growth. Simultaneously, we will skew stem cell differentiation trajectories and assess their influence on cell behavior and organ shape. The outcomes of this project will provide novel insights into the coordinated developmental programs governing stem cell fate and morphogenetic events, both essential to tissue formation. Moreover, they might
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Linking Epidemiology and Laboratory Research on Transboundary Animal Diseases and zoonoses in China and EU'.

assistant: **Concept**

The continuous growth of the world population translates into a demand of animal protein that can only be achieved through technological advances in farming,  intensification, and expansion of farmed land. These pressures, combined with the increasing international trade of animals and their products, will lead to the rapid spread of animal diseases across borders and the emergence of new pathogens. This can have a huge impact on trade, livelihoods and public health. China is no exception and is in fact the world’s largest livestock producer and consumer, with pig and poultry meat being the most consumed meats.Research has many of the answers to prevent and control animal diseases, either through the understanding of their spread (epidemiology) or through better diagnostics for disease detection and surveillance. Both the European Union (EU) and China are two major worldwide players in animal health research. With dozens of institutions working on livestock health, the cross-border coordination and networking of research becomes a top priority to avoid duplication, while maximizing efforts by bringing together new ideas, expertise, technologies and funds.LinkTADs brings together world-class research institutes and experts in cross-border cooperation with the aim to coordinate research between the EU and China, thus improving scientific excellence in animal health (epidemiology and laboratory). Main objectives:• identify the priority areas, where joint actions are needed• link the research activities carried out on by European and Chinese research programmes• ensure a wide-range networking of scientific communities and stakeholders• provide a long term vision and achieve coordinated planning on future common research• contribute to the international policies of the EU• i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'The Patterns of Conflict Emergence: Developing an Automated Pattern Recognition System for Conflict' to be submitted under Horizon 2020.

assistant: **Abstract**

Are there recurring patterns in the escalation and emergence of wars? The idea that history may repeat itself is old. Butrecent advances overcoming methodological and data barriers present an opportunity to identify these recurrencesempirically and to examine whether these patterns can be classified to improve forecasts and inform theories of conflict. Ipropose to combine new methods—using the shape of the sequence of events rather than its raw values—and novel dataon conflict from finance, diplomatic cables, and newspapers, to extract typical pre-war motifs. Just as DNA sequencing hasbeen critical to medical diagnoses, PaCE aims to diagnose international politics by uncovering the relevant patterns in thearea of conflict. Our goals are to:(i) Identify patterns in the pre-conflict actions using data on conflict events—from the onset of WWI to Hamas’s rocketlaunches—and in their perceptions using data from financial markets (the “crowd’s” perception), news articles (the “experts”),and diplomatic documents (the policy-makers). This will allow us to evaluate the patterns of escalation over differenttimescales—from the decade to the minute. The similarity between temporal sequences will be measured using algorithmswhich allow for flexible matching, such as Dynamic Time Warping.(ii) Evaluate the utility of these patterns to improve forecasts of conflict with both historical and live out-of-samplepredictions. Our results, using shape-based classification methods, will be made public and evaluated in real time. Moreover,using new measures of complexity to distinguish regular, chaotic, and random behavior, I will measure possible fundamentallimits to the predictability of conflict events.(iii) Summarize the core features of dangerous patterns into motifs—recurring patterns—that
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'NANOSCIENCES, NANOTECHNOLOGIES, MATERIALS AND NEW PRODUCTION TECHNOLOGIES DEPLOYMENT IN LATIN AMERICAN COUNTRIES' in the context of a Seventh Framework call.

assistant: **Objectives**

A thorough approach to nanotechnology and advance materials development must take into consideration the international dimension, in terms of R&D, access to information and regulation. International cooperation, including collaboration in research but not limited to this, is an integral part of the Commission’s policy in all areas of the Action Plan. However, despite the fact that international collaboration has been made so far; there is still a challenge of filling knowledge gaps with less industrially advanced nations in order to enhance quality of life and industrial competitiveness in those areas where Nanotechnology has the potential.  European industrial players and research organizations seek new collaborative agreements in order to share risks and explore new market opportunities. On the other hand, Latin America has started new nanotechnology development programs in the last ten years. However, according to national agencies, the investment in nanotechnology R+D and the results achieved remains now relatively unpretentious.The main objective of NMP-DeLA project is to develop a series of activities between European and Latin American countries, aiming to strengthening the local research and training potential, as means to achieve the goal of deployment of Nanomaterials technologies on those areas of major social challenge in Latin America: energy, water and Health. This will be achieved through:• Networking, education and training in Advance materials (nanosciences, nanotechnologies, materials and new production techs).• Building new skills, aiming to enhance and strengthening the local knowledge in Latin America about nanomaterial technologies.• Boost synergy with local/regional policy and cooperation programs related to advance materials.• Exchange of best pr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'The next-generation digital inspection platform for fully remote supply chain monitoring' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

The global Testing, Inspection and Certification (TIC) market is expected to reach €250 billion by 2024, driven by international trade, tightening regulations and outsourcing. This market is also changing radically and will experience a complete technological revolution, as traditional TIC services are now in decline in favor of digitalized alternatives. This is particularly relevant for the manufacturing vertical, where manufacturers and retailers still heavily rely on third party quality inspectors to monitor the supply chain. This process is expensive, complex and unreliable, since real-time inspections are not feasible on remote locations. Additionally, current digital alternatives are not fully automated and lack the tools to guarantee a full inspection. Existing partial solutions only provide highly specific tools and do not offer cross-sector factory inspections.Our team of highly experienced experts in the TIC field is developing the CyRaCo Box, a unique and patent-pending tool that provides a reliable, efficient and real-time remote factory inspections. It combines 3D Modelling, Augmented Reality, Cloud technology, analytics and smart sensors to offer completely automated and fail-safe factory inspections. As a result of the improved efficiency and automation, it also reduces traditional inspection costs by 90%. The CyRaCo Box wil democratize supply chain monitoring, promote supplier accountability and pave the way towards real ethical sourcing. Additionally, it will also facilitate international trade for European SMEs, which do not have the necessary resources to develop expensive in-house inspection infrastructure. The unique features of the CyRaCo Box will allow us to grow exponentially and disrupt the inspection market, with a highly scalable and flexible
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'New Routes for the Solution NMR Investigations of Extra Large Biomolecular Assemblies', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

The cell is a collection of dynamic molecular machines. NMR spectroscopy is the method of choice to observe, at atomic resolution, complex conformational changes, transient interactions and dynamics of proteins. Introduction of methyl specific labelling technology has enabled solution NMR studies of protein assemblies of several hundred kDa. However, this strategy is mostly restricted to symmetrical and thermostable protein assemblies, precluding applications to large medically relevant biological complexes. The increases of linewidths and the high number of signal overlaps hamper the NMR spectra analysis of most hetero-oligomeric large assemblies studied at room temperature. In this project, we will develop two complementary concepts to significantly simplify both NMR spectra and corresponding site specific analysis.  We will build a multi-site specific labelling method enabling observation of NMR signals only for the sites of interest in a large protein complex. We will invent a combinatorial strategy to reduce the time required for site-specific identification of each individual NMR signal from a few months to a few hours. New 1H-frequencies edition schemes will be introduced to enhance significantly the NMR spectras resolution of very slow tumbling biological particles. These groundbreaking NMR methods will be validated using therapeutic antibodies (150 kDa), ribosome (2.4 MDa) samples, and will be used directly to capture the mechanisms of ATP-fueled human chaperonin (1 MDa) in complex with the aggregation prone form of Huntingtin. This project will provide new technological breakthroughs to push biological applications of NMR significantly beyond its current boundaries. We anticipate that the simplification of the NMR analysis resulting from the new developed NMR
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'The contribution of thalamocortical projections to high cognitive functions (speech processing, working memory and attention) in sighted and unsighted populations' to be submitted under Horizon Europe.

assistant: **Abstract**

The proposed project aims to investigate the contribution of thalamocortical projections to high cognitive functions such as speechprocessing, working memory and attention in sighted and unsighted populations. In the last decades, advances made in magneticresonance imaging (MRI) have shed light on the cortical regions subserving these processes. However, less research has investigatedthe role of thalamocortical pathways in these high cognitive functions. This could be due to the lack of detailed probabilistic atlases ofthe human thalamus or the small size of the thalamic nuclei as compared to regular voxel sizes. Therefore, the recent creation of thefirst probabilistic atlas of the human thalamus (developed by the host group), opens the door to investigate to what extentthalamocortical connections relate to speech processing, working memory and attentional abilities. We will further investigatewhether the involvement of thalamocortical projections in the abovementioned functions differ between sighted and unsightedindividuals, since research conducted in blind population has reported enhanced auditory processing at the thalamic level, alteredthalamocortical connectivity and superior skills in the previous cognitive functions. To address these scientific questions, we will use amultimodal MRI approach that combines functional and structural MRI indexes with behavioral measures. Using regression models,we will assess the degree to which thalamocortical connections help to further explain speech processing, working memory andattentional abilities as opposed to just considering cortical indexes, as it was done in the past. The results of the present researchproject may have important implications as they could open a new avenue at the theoretical level (updating pre-existin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Adaptive Control for Metal Cutting' (ADACOM).

assistant: **Innovation**

The project ADACOM will address main industrial sectors. automotive (DC, LOLA, CRF), electronics (BOSCH) and printing machine sector (HDM). Next to those OEM’s, OEM’s supplier and especially sensor manufacturer suppliers (Kistler) will participate in this project in order to reach the following goals:  Core development will be an Adaptive Machining Systems for metal cutting operations (milling, turning, gun-drilling, grinding), which consists of a sensor and actuator systems for online manufacturing control related to the part quality. The major aim is to achieve an Online Quality Control systems within the mass production of the above mentioned industrial sectors. In ADACOM this aim will be achieved by separating the single components of such an adaptive machining system into a modularised monitoring system. This modularisation will first of all give the possibility to adapt the different modules in this way that a flexible use of the adaptive system for different machining operations is possible. Next goal of the development within this project will be the realisation of one central system for different processes, which incorporates the flexibility towards changing production situations, different machine tools and different work piece materials. This flexibility of the ADACOM-System will be reached by developing a standardisation of the Adaptive System components. Issues like standardised interfaces, which guarantee “Plug and Produce”-production, will be achieved by standard data formats throughout the whole production sequence. This implies a connection of manufacture to design and should give the possibility use the same data in the design, production and quality assurance of a mass product.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Moving Emotions towards confidence in the Transformative Appropriation for a Meaningful Understanding of cultural heritage: a neuroScientific approach to EUropean Museums' in the context of a Horizon Europe call.

assistant: **Objectives**

META-MUSEUM aims to create empathic encounters where citizens can understand the CH transformative nature through active participation, emotional involvement and co-creation; to develop the “TransforMeans theory” and related new professional skills, based on Neuroscience evidence; to provide cultural professionals with principles and tools for designing cultural experiences and to monitoring the effectiveness of communicative/narrative solutions; to reach different segments of citizens, included disaffected public and non-public; to foster empathy, confidence and resilience toward contemporary changes; to validate an appropriate measurement of empathic responses, confidence and resilience in CH users, via Neuroscience’s method.META-MUSEUM adopts a transdisciplinary approach and a strict interrelation between theoretical and experimental work. The first one will explore and develop in-depth the “TransforMeans theory” principles, develop stimuli to make people understand the CH transformative nature and encourage co-creation and personal interpretation. The experimental work will measure the audience's cognitive, psycho and neurophysiological responses to stimuli, and interpret indicators related to confidence and resilience (intended as a capacity to positively react to changes).The “TransforMeans theory” principles will be tested in 3 different settings (pilots): 1) traditional cultural setting: museums; 2) non-cultural setting: hospitals (WITHOUT focusing on “therapy results”, but only on the CH power on people particularly lacking in confidence and positive thinking); 3) hybrid setting (physical and virtual), in urban contexts and via social media.The META-MUSEUM objectives mobilise multidisciplinary expertise, provide evidence-based principles and guidelines; promote
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Photons for Quantum Simulation' (PhoQuS) targeting Horizon 2020.

assistant: **Abstract**

Quantum simulation is an emerging and exciting field for which several systems, such as ultracold-atoms, trapped ions or superconducting circuits are being actively investigated. In this project we aim to develop a novel platform for quantum simulation, based on photonic quantum fluids. Quantum fluids of light can be realised in different photonic systems with suitable nonlinearities, allowing to engineer an effective photon-photon interaction. The photon-photon interaction necessary to form a superfluid is provided by the optical nonlinearity of the medium.  We will first fully characterize the superfluid and quantum turbulent regimes for quantum fluids of light, investigating the propagation in optically controlled landscapes with the demonstration of important milestones such as many-body localization and the superfluid to Mott–insulator transition. Based on these achievements and on the unprecedented flexibility offered by the all- optical control in quantum fluids of light, we will implement quantum simulations and simulate systems of very different nature, ranging from astrophysics to condensed matter. Fundamental open questions such as superconductivity, black hole physics, and quantum gravity will be addressed within the photon fluid platform.


**Keywords:** Quantum Fluids of Light, Quantum Simulation, Photon BEC