RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Nanostructured van der Waals materials for enhanced light emission' in the context of a Horizon 2020 call.

assistant: **Objectives**

This research proposal aims at exploring the potential of atomically-thin van der Waals (vdW) materials as highly efficient single-photon and nonlinear light sources towards their implementation in optical devices. In the context of nano-optics, an important element towards the development of practical photonic-based technologies is the achievement of bright and stable light sources as well as a precise control over quantum emitters. So far, the development of photonic devices is limited by a number of issues which can be addressed by the use of two-dimensional (2D) vdW materials. They present interesting excitonic properties  such as strain-induced localization of emitters and inherent optical nonlinearities but the low quantum yield hinders their use in optical devices. Therefore, there is a real need to enhance the photoluminescence of vdW materials. One way to address the low quantum yield is by utilizing nanostructures to increase their emission rate. This project will be carried out with Dr Sapienza at the Imperial College London in collaboration with a secondment host, Prof. Tartakovskii at the University of Sheffield. My experience with nanoscale hotspot manipulation for fluorescence enhancement and the activity of the hosts with quantum emitters and vdW materials will permit a collaborative and interdisciplinary research programme at the interface between 2D materials and nano-optics. If successful, this proposal will allow me to advance my career in the field of nanophotonics and participate in diversifying the achievements of the host groups in nonlinear optics and plasmonics. Furthermore, the potential outcomes will provide a major step towards the implementation of vdW materials in photonic devices, thus establishing European leadership worldwide in the sch
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Canine genomics and the evolution of phenotypic diversity' (2002-2006).

assistant: **Concept**

Rapid generation of morphological change has long puzzled biologists, as it is difficult to reconcile with the low frequency at which point mutations occur. In general, the mechanisms that underline the genesis of extreme diversity are unknown, but they ma y be relevant to many situations in the natural world (i.e. adaptive radiations). Here I propose the dog as a model for the study of such mechanisms: they have an extreme morphological diversity; their ancestor, the wolf, is still extant and available for comparison; and the genome has been recently sequenced and a large number of markers are available. I plan on studying two of the mechanisms that can contribute to the generation of diversity in dogs. Also, I would like to apply current knowledge on the do g genome to understand processes and forces acting on natural populations of wolves. Some studies have shown that recombination rates increase with stress level. I hypothesize that the change in life style in dogs compared to wolves may have resulted in higher recombination rates. As a consequence, new allele combinations have arisen providing the raw material for artificial selection to act upon. I will test this hypothesis by typing microsatellite markers with known locations in the sperm of dogs and wolves. Also, SINEs and tandem repeats can have effects on gene expression. I will study variability in SINEs and tandem repeats associated to genes with known function in dogs and wolves and try to correlate their diversity with phenotypic diversity in both species. In North American and European wolves I will compare coat colour gene sequences. Moving to a European Host Institution in accordance with my professional needs will contribute to the diversification of my competences and to my development as an independe
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Implementing access control mechanisms using rewriting techniques' demonstrating excellence, impact and implementation quality for a Sixth Framework call.

assistant: **Abstract**

Static behavioural analysis of mobile computer programs is an active area of research, many fundamental behavioural properties and security issues for mobile computing have to be established. We believe that rewriting can provide a formal basis for the study of a broad range of security issues, ranging from the specification, implementation, and validation of security policies, to the analysis of logs and the development of tools for intrusion detection.In this project we will focus mainly on access control within distributed and mobile applications. Special language primitives and reasoning tools are needed to specify access control policies and to prove their properties. The purpose of this project is to tackle this problem by using a well-known tool: rewriting theory, possibly combined with type systems. We plan to develop an implementation of the existing access control mechanisms, supported by centralised or distributed systems, using a term rewriting framework.We will extend the usual notion of rewriting to accommodate distributed code and investigate a theory of access control described in terms of a set of rewrite rules and their reductions. The rewrite system thus obtained will be used as a basis for the design of a distributed, mobile language where programs are defined as collections of rewrite rules with built-in mobility and access control mechanisms. The obtained rewrite-based language will be applicable in mobile distributed environments, in particular the Semantic Web environment.An advantage of the rewriting framework over a more traditional logic-programming framework is its expressivity: rewriting encompasses several computation paradigms, including functional, logic, imperative and concurrent ones. Another advantage is that we can profit from the rap
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Promoting sustainable agriculture for pollinators'.

assistant: **Objectives**

Threats to pollinators and pollination services that support agriculture and provide benefits to people are a worldwide problem. AGRI4POL’s ambition is to assist the transition of agriculture from being a pressure on pollinators to becoming a positive force for managing and restoring pollinator biodiversity, crop pollination services, and co-benefits to ecosystems and people. To achieve this transition towards more pollinator friendly farming systems and value chains, AGRI4POL will advance scientific understanding of crop-farming system-pollinator relationships from the crop gene to the agroecosystem. By evaluating the genetic basis of crop floral traits attracting and rewarding crop pollinators, we will identify candidate crop lines suitable for breeding future pollinator-smart varieties. We will study how pollinator-crop relationships are modified in space and time, by the diversity and rotation of crop species and varieties, by ecological infrastructure (EI) comprising landscape features and non-crop habitats, and by future climate or land-use change. Synthesising this information from the gene to agroecosystem scale will allow us to provide integrated recommendations for optimising landscapes for crop pollination, pollinator biodiversity and multiple ecosystem benefits. AGRI4POL research will be framed and supported by early and sustained multi-actor engagement along agri-food chains to assure its relevance and the acceptability of management options to farmers and society. This multi-actor approach will also enable assessments of the socio-economic and policy obstacles and opportunities affecting the feasibility and uptake of pollinator-friendly farming at [sub]national, European and international scales. AGRI4POL will therefore showcase to farmers, agri-food actor
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Engagement Art: Regional Islamic and Global Pragmatist Aesthetics' (ENART).

assistant: **Concept**

ENART is an integrated research and training programme for innovative knowledge transfer and career development. It will be implemented at the Department of Society and Global Studies at Roskilde University, Denmark (Beneficiary, host of the Incoming Phase), the Department of History of Art at the University of Michigan, USA (Partner Organisation hosting the Outgoing Phase), and SALT, research and exhibition centre in Istanbul and Ankara, Turkey (host of the intersectoral Secondment). The interdisciplinary constellation of these organisations and the supervision they provide complements the researcher’s own art-historical formation and endorses her research project in transregional Islamic Art History around which ENART’s comprehensive dissemination and public-engagement activities are built:The research project is entitled “Engagement Art: Regional Islamic and Global Pragmatist Aesthetics”. “Engagement art” is a new concept that this project introduces in order to define a hitherto overlooked approach to art. This approach conceives of art as a practice and medium which is continuous with everyday life. This project asks what ideas informed engagement art and what practical and historical circumstances interfered with its development and actual enactment. To answer these questions the project traces the development of engagement art from its conception in Istanbul in 1909 to its implementation at the Art-Craft Department in Ankara in 1932. Thereby the research centres on the modes of confluence of regional Islamic and global pragmatist aesthetics. Apart from introducing a new concept to Islamic Art History, the project seeks to develop a new method for the study of non-canonical art and strengthen ties between the history of art made in and outside of Europe, as well a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Nose to Brain Delivery of Antibodies via the Olfactory Region for the Treatment of Multiple Sclerosis Using Novel Multi-functional Biomaterials Combined with a Medical Device'.

assistant: **Innovation**

The overall aim of N2B-patch is the development of a new innovative N2B drug delivery technology based on the synthesis of a biomaterial-based innovative galenic formulation that will be applied with the aid of a novel medical device equipped with a container closure system (CCS) as a hydrogel patch to the nasal olfactory region for the chronic treatment of MS. The galenic formulation will consist of drug loaded biodegradable polymer particles (e.g., chitosan, polylactic-co-glycolic acid, PLGA) embedded into a biodegradable hydrogel matrix (e.g., hyaluronic acid (HA)-based) to be deposited as a patch onto the olfactory region. A pH-sensitive, mucoadhesive particle coating (e.g., chitosan, chitosan derivatives) will ensure an environment-specific adhesion to the olfactory epithelium. This novel technology will largely enhance the controlled and sustainable delivery of drugs and increase the drug bioavailabilty to the CNS. NogoA antagonist NG-101 will be used as an active pharmaceutical ingredient (API). Proof of concept studies and initial clinical data have proven the enormous potential of blocking NogoA for spinal cord remyelation and axonal integrity. However, monoclonal antibodies (mAb) like NG-101, do not sufficiently cross the BBB. The sustainable and controlled release of NG-101 to the CNS will be achieved via the transport of embedded polymer particles to the olfactory epithelium, the subsequent release of API and permeation through the olfactory region, the only part of the nasal epithelium which is in direct contact with the brain. The direct transport route from the nasal cavity to the brain, bypassing the BBB, offers an exciting mode of central nervous system (CNS) drug delivery not only for demyelinating disorders but also for other CNS indications, e.g., st
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Toxic pollution detection in ground water : from real time early warning to overall assessment' to be submitted under Fifth Framework.

assistant: **Abstract**

Decades of unregulated disposal of toxic wastes in the NIS countries have created major environmental pollution problems seriously affecting public health. The hereby project proposal involves the collaboration of specialised institutions from Russia, Ukraine, Georgia and Armenia, countries currently facing severe problems of toxic pollution in their ground water. Technical assistance is provided by a European Consortium of highly specialised companies (including three SMEtmS) and a major institution acting as overall coordinator, whose experience in the specific topic can be consider as global. The project will be focused on groundwater pollution monitoring, assessment, environmental management, early warning; training and civil awareness. In conjunction to the above, specially trained local scientific and technical groups will be created, that eventually take over the running of the project, during and after its completion.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Development of New and Novel Quality Control System for the Inspection of Titanium Components in Safety Critical Applications in the Aerospace Industry'.

assistant: **Innovation**

European SMEs in the field of none destructive testing do not have the technological capability to reliably test titanium materials, and as a result risk are losing competitiveness in this €600million global market. Titanium is important material in the manufacture of new components in many important industries, including aerospace.    An automated phased array, ultrasonic NDT method supported with eddy current technology, integrated with the manufacturing process. Currently, beam steering techniques require prior knowledge of the exact geometry and acoustic properties of the material and also require an extremely precise alignment of the probe to the component under test.  The QualiTi Consortium SMEs will develop inspection of titanium at the component manufacturing stage.  The QualiTi work programme is broken down logically into work packages and includes RTD work, management, training, dissemination and knowledge management activities. The QualiTi Consortium are suited and committed to the tasks allocated to them, are able to achieve their S&T objectives and commercialise the deliverables.    The SME proposers consider that the QualiTi system will provide sufficient competitive advantage to enable annual growth rates of at least 20% in SME sales turnover over the four years following project completion. The exploitable prototype systems developed in QualiTi will reduce world spending on inspection in the aerospace market by >10% and thus generate savings of approximately €66m worldwide per annum four year after project end. The corresponding European saving is €19m.  After outsourcing research the QualiTi SMEs will become more competitive.  All the QualiTi deliverables are patentable. The QualiTi project will deliver an integrated inspection solution, to meet the req
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Detecting Polygenic Adaptation Targeting Gene Expression Regulation In Humans Using eQTL Networks.'.

assistant: **Concept**

Polygenic adaptation, in which small changes in allele frequencies co-occur at multiple variants, has been proposed to be a major adaptive mechanism for complex phenotypes. Most approaches to detect polygenic adaptation consist in combining signatures of positive selection across functionally homogenous sets of genes or variants. However, few studies have looked at regulatory variants and none have accounted for the tissue-specificity of gene expression.Here, we propose to combine network biology and population genetics methods in order to detect polygenic adaptation acting on complex phenotypes through gene expression regulation. First, we will identify communities of regulatory variants that coregulate groups of genes, by representing both cis- and trans-expression quantitative trait loci as bipartite graphs. We will then search for communities enriched for signatures of weak positive selection to identify regulatory variants under polygenic adaptation. After evaluating the power of our approach using simulations, we will apply it to data from several tissues from the GTEx project. This will allow us to identify and characterise biological functions evolving under polygenic adaptation, taking into account the tissue-specificity of their expression. We thus hope to better understand the extent to which polygenic adaptation shaped the human genetic diversity and susceptibility to complex diseases.The PATTERNS project will be led by the experienced researcher (ER), who has worked on network biology during her postdoc in the USA. She will collaborate with the supervisor who is an expert in theoretical population genetics, and receive training in teaching, grant writing and management and communication. This will help the ER in her path to independence by strengthening her
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Biowaste and Algae Knowledge for the Production of 2nd Generation Biofuels' (BIOWALK4BIOFUELS).

assistant: **Concept**

The Biowalk4Biofuels Project aims to develop an alternative and innovative system for biowaste energy recovery and use of GHG emissions to produce biofuels, using macroalgae as a catalyser, in a multidisciplinary approach. The objectives of the project are: production of a cost-efficient biogas without using cereal crops; optimise the production of biogas per amount of biowaste and CO2 used, with low land use for plant facilities; and increase and optimize the types of biowastes that can be utilised for biogas production. To achieve the underlined objectives, research activities are to be carried out on the selection of adequate macroalgae species that can reach high output biomass yields and high carbohydrate content. Pre-cultivation of protoplasts  will allow to obtain easily available biomass for feeding the cultivation open floating ponds within shorter periods, thanks to the rapid proliferation of germplasm, diminishing the life-cycle of macroalgae.In addition, the relationship between growth and energy potential of selected species with the amounts/characteristic of GHG emissions and biowaste introduced in the cultivation medium is to be studied. . After fermenting the algal biomass and other biowastes, the cycle is closed by producing biogas to be used for electricity and heat generation and as a transport fuel. A high quality biogas is expected, hence a purification step will proceed the final product. Furthermore, organic residues output from the methanation biodigestor are to be used as fertilizer after solid/liquid separation. The liquid fraction of the digestate will be treated in a biological oxidation system .A portion of the unseparated outlet effluent from the oxidation system (solids + liquid) will be fed to the macroalgae cultivation (instead of the en