RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Advanced methods for the removal and monitoring of polar organic contaminants' (PolarClean) targeting Seventh Framework.

assistant: **Abstract**

The aim of the project is to develop advanced methdologies for the decontamination and monitoring of emerging polar contaminants in wastewaters and drinking waters.There are no known technologies for cleaning e.g. endocrine disruptors, molluscicides, acrylamide, which are major problems affecting the quality of drinking water world-wide and can degrade aquatic ecosystems. Methods based on micro- and nano-composite materials and heterogeneous catalysis with superior cleaning properties will be developed and applied to achieve efficient and environmentally friendly remediation technologies. The decontamination strategy will be further developed as a new high throughput analytical tool for monitoring trace amounts of pollutants in water.The project will tailor the structure of micro and nano-size carbon beads; nanotubes and graphene oxides to trap highly polar contaminants from water whose removal is not feasible today; embed the most effective structures in a polymeric matrix; and develop a process to decontaminate the material by means of heterogeneous catalysis where the adsorbent will act as catalyst in the degradation reaction. The carbon-based composites developed for water remediation will be optimised for use in analytical processes.The outputs of the research will contribute to the betterment of ecosystems and human health through the improvement of water treatment technologies, and science with new methodologies to trap, degrade and monitor highly polar contaminants from water. Removal and monitoring highly polar small-size molecules from water is a significant challenge and an urgent need of today.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Urban europe, between identity and change' goes beyond current state-of-the-art under Fifth Framework.

assistant: **Innovation**

In order to adequately address its research and training topic, the Urb EUROPE network has the ambition to develop a meta-project, aimed at linking the outputs of recent and/or ongoing research in different disciplines involving the urban dimension of Europe. The flourishing of research projects and networks carrying out empirical fieldwork in European cities signals the recognition of the crucial character of this dimension, even though, little effort has been devoted in building up a solid interdisciplinary knowledge basis integrated with a highly structured training programme. Filling this gap is our main objective. The establishment of this link will be organized around three main areas of analysis :1. The analysis of how global changes and local impacts are conceptualized in theories and through which methods they are investigated;2. The analysis of how changes impacted on the built environment (gentrification, sub-urbanization and segregation);3. The analysis of how the changes impacted on the role of local social policies and governance. The investigation of these three areas - highly interrelated one another - has the main goal of attaining a better understanding of the tension between identity and change in European Cities (the local-global link), of the existing differences and of the directions of change (the convergence-divergence hypothesis). Each area of investigation, however, has specific objectives, which are outlined in detail in this proposal. T o these objectives we have to add an additional and very innovative objective: we aim also at providing the visual support to the issues tackled in the different thematic areas. To give an example: when we will address issues of gentrification we will provide images from neighborhoods of different European cit
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Medical Phase Contrast X-ray Imaging with Laser Plasma Accelerator'.

assistant: **Concept**

Cancer detection at an early stage is crucial for subsequent therapy success. To achieve this goal, an effective screening should rely on a specific tool that should be not only non-invasive but also adaptable to patients and their diseases. Widely used nowadays, X-Ray imaging (RX) is a well-established cancer screening technique. However, it poses major problems of (i) detection of tumours at early stages when they are small and of low contrast, (ii) dose deposition in a body, especially for frequent and long term monitoring and (iii) energy tunability of the X-ray source to optimize the imaging. The project XMED aims at tackling simultaneously these three strong limitations, and to come out within 18 months with a demonstrator. For this purpose the most advanced electron beams produced by laser plasma accelerators will be use to radiate a bright, tunable X ray beam using the recent all optical Compton scheme.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Travels, transmissions and transformations in the 3rd and 2nd millennium BC in northern Europe: the rise ofBronze Age societies' to be submitted under Seventh Framework.

assistant: **Abstract**

Research problem: The 3rd and 2nd millennium was a period that saw major social and cultural transformations in Europe, from migrations and the introduction of metal (the Bronze Age) to new cultural identities and languages. As these two millennia were formative for Europe’s later history, these are hotly debated issues. However, they can now be resolved, at least in part, by the application of new science-based methodologies and the development of new interpretative frameworks.Aims and methodologies: The project does so by adopting an interdisciplinary methodological approach that combines science and culture. Isotope tracing in combination with recent advances in ancient DNA is employed to test human origins and movements during the two millennia, as well as the origin of wool and textiles. Lead isotope is adopted to trace the origin of copper. Based on this the project will document and explain the forging of new identities and new types of interaction during the 3rd and 2nd millennium BC in temperate northern Europe, but with implications for western Eurasia.Progress and originality: Accomplishment of front-line research results by combining archaeology with new developments in the natural sciences to produce new knowledge about the mobility of people, animals, things, ideas and technologies. This will allow a critical comparison of different types of evidence on mobility from DNA to strontium isotope analyses, and will lead to improved knowledge about the ways in which European regional cultures and identities were formed in the Bronze Age through interaction. Finally, the project will potentially change our understanding and thinking about human mobility as a key factor in cultural and social change.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Clinical Validation of In Vivo Imaging for Detecting Immune Dynamics' (VIVID).

assistant: **Innovation**

VIVID is a project on the Clinical Validation of In Vivo Imaging for Detecting Immune Dynamics. Optimising cancer treatment is a challenge, especially with combination therapies and patient variability. The ability to study cell migration in a quantitative and non-invasive manner in vivo, of endogenous cancer-fighting immune cells and administered therapeutic cells is essential for biomarker-driven and personalised clinical trials. Our imaging agent, BEACONs, allow for multimodal, quantitative imaging of cell populations; here with quantitative 19F MRI and fluorescence. This project will demonstrate and validate the feasibility of cell tracking using multimodal imaging and increase the maturity of BEACONs (to TRL 5-6) through a first-in-man clinical trial in current cancer standard of care.Our specific objectives are to 1) Set up a clinical trial of interest to large pharma, here the imaging of labelled immune cells in a neoadjuvant setting; 2) Build a business plan and create a spin-off; 3) Ensure that any new IP is protected; 4) Perform outreach towards patients and end-users.The potential societal impact of using BEACONs includes being able to assess and adapt complex therapies in major diseases such as cancer organ transplants, allowing a more targeted treatment and reducing patient burden such as negative side effects of ineffective treatment. The economic benefit of using BEACONs is large, while also reducing animal use, and enabling early assessment of cell therapies and cancer therapies.VIVID allows the application of our technology in a new field -that of personalisation of cancer therapy- aside from cell therapies, increasing our potential customer base (oncology drug market expected $285B in 2023).


**Keywords:** Imaging agent,  non-invasive cell tracking,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'TELEMATIC MANAGEMENT OF INSULIN DEPENDENT DIABETES MELLITUS' under Fourth Framework.

assistant: **Concept**

Diabetes affects some 30 million citizens in the EU, accounting for an estimated 7% of its health budget. T-IDDM will cut costs and time devoted to insulin therapy, by using telematics management to monitor patients and facilitate their access to treatment. In a proposed two-part service, one unit is to assist patients with local consultation procedures and similar support, while a workstation helps the doctor deal with long-term patient management. These modules intercommunicate, so that therapeutic strategies can be prescribed to the patient, who then transmits relevant data back.Diabetes causes metabolic alterations and long term invalidating complications related to renal, neurological, cerebrovascular, cardiovascular and peripheral vascular diseases. In Europe about 30 million people suffer from diabetes; 20% of them require exogenous insulin administration to survive (insulin-dependent patients). Recent medical evidences show that a better metabolic control achieved through Intensive Insulin Therapy can delay or prevent the development of long-term complications It requires frequent insulin injections, accurate blood glucose monitoring and strict surveillance by health care professionals. This patient management procedure is expensive and time-consuming. It is calculated that 7% of the total European health care expenditures is absorbed by diabetes care and the major part of this budget results from the management of the above mentioned complications. The administration of an appropriate therapy and the reduction of chronic complications are expected to produce economical benefits for patients, their families, and the community. A considerable saving of money could be obtained through the use of telecommunication services for the active monitoring of the patients.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Frontier applications of cryogenic detectors to astroparticle physics, material sciences, semiconductor industries, x-ray fluorescence analysis, macromolecule mass spectroscopy, nuclear-subnuclear physics' in the context of a Fifth Framework call.

assistant: **Objectives**

The activity of the network is characterized by a unique multidisciplinarity, from solid state to nuclear and sub nuclear physics, from cryogenics to astroparticle physics together with the related techniques. All teams are universally known for their competence in one or more of these subjects and the network, as an ensemble, in all of them. This multisciplinarity has an obvious training content bringing together young physicists. Their exchange among the groups will lead to a much wider and extended knowledge also on technical subjects. These have an obvious impact in the European Industry, with which the teams of the network are in close contact and collaboration. Subjects like development of low noise electronics, study of the properties of materials at low temperature, crystal growing, measurements of low environmental radioactivity at an unique international level have an obvious training content even from the technical point of view.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fifth Framework proposal for the project 'Institute of aquaculture'.

assistant: **Objectives**

Description:The Institute of Aquaculture is one of the largest institutions devoted to aquaculture science in the world. With over 100 staff the Institute has unrivalled expertise and experience in research leading to the development of sustainable aquaculture systems. Major research areas include disease and health management, reproduction and genetics, nutrition and biochemistry, environmental impact, and aquaculture systems and development. There are over 1200 m2 of dedicated and well-equipped laboratory spaces covering virology, microbiology, parasitology, pathology, electron microscopy, biochemistry, nutritional physiology, immunology, reproductive physiology, radio immunoassay, molecular biology, genetics, water chemistry, ecotoxicology, crustacean biology, and geographical information systems. The Institute is unique within Europe in being able to offer within one institution this range of facilities devoted to aquaculture research. In addition, there are 750 m2 of excellent aquarium facilities at Stirling suitable for cold and warm water freshwater species, and for work with infectious diseases. Nearby there are further extensive freshwater facilities and the Institute also has a semi-commercial scale marine facility on the west coast of Scotland.Application:To submit research proposal to use these facilities please contact Dr R Wootten.Project Manager:Rodney Wootten, Institute of Aquaculture, Stirling FRK9 4LA, United KingdomTel: +44-1786-467870Fax: +44-1786-472133E-Mail: rw3@stir.ac.uk
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Sustainable rubber for the environment.' under Horizon Europe.

assistant: **Concept**

Current rubber sources are unsustainable. Existing rubber products are derived from natural rubber from the rubber tree. The problem with the source of this rubber is deforestation of tropical rainforest and competition with food production. Rubber plantations are threatened by climate change and are vulnerable to disease and environmental hazards. Almost the entire global supply of natural rubber  some 11 million tonnes in 2015  comes from Southeast Asia. Scientists at Edinburghs Botanic Gardens estimated that more than 50% of plantations in the region might not be sustainable. The second source of rubber is synthetic fossil-fuel based rubber. It is mixed with strong chemicals during production. NORDIC BIO-RUBBER facilitates the transition of fossil-centered industry of today to a sustainable bio economy, allowing us to build a Europe based supply chain, decreasing dependencies on Asia for the production of consumer goods, which translates to a more robust economy.


**Keywords:** Recyclable rubber,Bio, refinery,Sustainability,Bio-rubber,New Value chain,Environmental engineering
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Direct Pathway Cloning of Neglected Bacteria in the Hunt for Novel (Bio-)Chemistry'.

assistant: **Concept**

To overcome recent global health threats, such as antibiotic resistance, a resurgence in the discovery of new chemical and thus biomedical diversity from microbial sources is needed. Genome mining in combination with heterologous expression is an approach that will overcome these challenges. It involves incorporation of yet uncharacterized natural product genetic loci into a fast growing heterologous host. For this approach, a prolific source of novel natural product gene clusters is vital. Our collaboration with the Zentralinstitut für Ernährungs- und Lebensmittelforschung (ZIEL, Technische Universität München) provides direct access to bacterial isolates completely unexplored in regards to their potential for natural product biosynthesis. Our genome analyses have revealed that many of the ZIEL isolates harbor a large number of uncharacterized natural product gene clusters. Thus, the aim of this proposal is to heterologously express natural product gene clusters from these neglected bacteria to discover novel natural product (bio-)chemistry. Because these organisms are poorly studied, the likelihood of discovering rare or novel biochemistry is immensely increased. Here, we will utilise a novel combination of synthetic biology techniques referred to as Direct Pathway Cloning. This will enable expression vectors to be constructed by large-amplicon PCR (up to 20kb) coupled to Gibson assembly. Development of the methodology is set to revolutionise synthetic biology and metabolic engineering. Downstream outcomes of this proposal will be the identification of novel, potentially bioactive natural products, the characterisation of unusual biochemistry and the addition of enzymes to the ‘biocatalytic toolkit’ for natural product synthesis and structural alteration.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Elliptic Integrable Systems: solutions, deformations and integrability' under Horizon 2020.

assistant: **Concept**

The proposal studies relativistic generalizations of quantum integrable models of Calogero-Moser-Sutherland (CMS) type and their deformations, and the correspondence between the CMS models and the Painlevé hierarchies. It is divided into several parts.  The first part investigates the van Diejen model (which is the most complicated model in the CMS family) and its sophisticated limiting case proposed by Takemura. The aim is to construct exact eigenfunctions of these two models using the kernel function methods. These eigenfunctions belong to an emerging new class in the theory of special functions.  The second part is devoted to the study of integrable deformations of the relativistic CMS model (Ruijsenaars model), going back to the works of Chalykh, Feigin, Veselov and Sergeev. In the trigonometric case, the deformed models are known to be integrable and the eigenfunctions of the principal Hamiltonian are given in terms of super-Macdonald polynomials. Using the kernel function identities, I will prove that all higher Hamiltonians of this model are diagonalized by the super-Macdonald polynomials. This will be used to establish orthogonality of the super-Macdonald polynomials. Extending this, I plan to establish integrability of the elliptic case. Furthermore, by using algebraic tools such as Cherednik operators and double affine Hecke algebras, and building upon a recent work of Chalykh, I will construct quantum Lax matrices for the deformed models in all cases.  Lastly, we aim to find a conceptual link between elliptic Cherednik algebras and higher Painlevé systems. Namely, first we will obtain the classical Inozemtsev system from Cherednik algebra by a Hamiltonian reduction. By relating this to the recent results of Bertolo, Cafasso, and Rubtsov, we will then find an