RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Deciphering molecular pathways of circadian clock communication', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

The overarching objective of this interdisciplinary project is to elucidate mechanisms through which billions of individual clocks in the body communicate with each other and tick in harmony. The mammalian circadian timing system consists of a master clock in the brain and subsidiary oscillators in almost every cell of the body. Since these clocks anticipate environmental changes and function together to orchestrate daily physiology and behavior their temporal synchronization is critical. Our recent finding that oxygen serves as a resetting cue for circadian clocks points towards the unprecedented involvement of blood gases as time signals. We will apply cutting edge continuous physiological measurements in freely moving animals, alongside biochemical/molecular biology approaches and advanced cell culture setup to determine the molecular role of oxygen, carbon dioxide and pH in circadian clock communication and function.The intricate nature of the mammalian circadian system demands the presence of communication mechanisms between clocks throughout the body at multiple levels. While previous studies primarily addressed the role of the master clock in resetting peripheral clocks, our knowledge regarding the communication among clocks between and within peripheral organs is rudimentary. We will reconstruct the mammalian circadian system from the bottom up, sequentially restoring clocks in peripheral tissues of a non-rhythmic animal to (i) obtain a system-view of the peripheral circadian communication network; and (ii) study novel tissue-derived circadian communication mechanisms.This integrative proposal addresses fundamental aspects of circadian biology. It is expected to unravel the circadian communication network and shed light on how billions of clocks in the body func
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Urban Knowledge Network Asia'.

assistant: **Innovation**

Asia’s mounting global importance includes a remarkable growth is urbanisation. Over 60 percent of the estimated 3.5 billion Asian population are now living in cities. A city’s most important asset is indeed its inhabitants (ADB 2008, Managing Asian Cities). If we are to address such unparalleled growth of Asian megacities, effective urban management must be informed by qualitative analytical knowledge and framed within a global, pluri-disciplinary experience that a transcontinental mobility programme such as the International Research Staff Exchange Scheme (IRSES) can provide. The challenge is for urban scholars and practitioners – policy makers or community leaders – to create a balance between the benefits and costs of urbanisation with a view of improving the quality of life of millions. The objective is to nurture more contextualised and policy-relevant knowledge on Asian cities, through exchanges and targeted case-study-based research among participants from the 11 partner institutions, with the European institutions playing a key role.Inspired by the new qualitative emphasis commanding European urban policy, the Urban Knowledge Network Asia intends to address critical urban development issues in Asia, taking into account the challenges of the diversity of urban societies, with their heterogeneous populations. The Urban Knowledge Network Asia aims, therefore, to study how Asian cities, taken as organic socio-spatial entities, manage their space and improve human liveability. To this end, the network put together by the International Institute for Asian Studies (IIAS) aims to host a variety of research projects covering three key areas of society in relation to the planning, management and governance of the urban environment: 1) shelter/housing (the house and the n
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Universities, Knowledge and Development for the next decade' to be submitted under Seventh Framework.

assistant: **Abstract**

The Spanish Presidency will organise a conference in the context of the the need to further develop links and synergies between the European Higher Education Area (EHEA) and the European Research Area (ERA) in the shift towards a knowledge-based economy with a new model of sustainable economic growth.The next decade is going to be important to shape the Europeans models of higher education and research based on the results of the Bologna and Lisbon 2010 processes and on the aspiration to develop a European Knowledge Area (EKA), as the conceptual framework facilitating the achievement of economic and social objectives of growth, jobs and social cohesion.The objectives of the conference will be:•Explore the interfaces between the EHEA and the ERA.•Reform of doctoral programmes•Modernisation Agenda for Universities:oConnections between higher education and innovation.oUniversity contribution to socio-economic development in the knowledge societyThe conference is aimed to promote a strengthened dialogue between policy makers and representatives of the university world together with other knowledge-related stakeholders such as research institutions, civil society organisations and businesses.A maximum of 200 participants is foreseen.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Multifunctional forest management-evaluation of policy and silvicultural means for mountainous regions' under Fourth Framework.

assistant: **Concept**

Management priorities in mountainous forests changed drastically during the last decade, as the importance of timber production decreased continuously whereas other functions partially new ones - became dominant. But, as many silvicultural measures do not cover their costs many forest owners give up management of their forests or prolong necessary treatments. As a consequence alpine countries are faced with the problem of how to ensure adequate management of mountain forests necessary to maintain their protective effects for settlement, infrastructures, and landscape. In the recent decade countries have developed their own policy measures to cope with these challenges. However, existing silvicultural and policy instruments are not well adapted to the new situation. Therefore, all existing concepts have to be evaluated before the background of these socio-economic changes as well as of progress in technology. The objective of the Concerted Action proposed is to assess existing national policy programmes and silvicultural techniques in six countries with regard to conception, practice, effectiveness and efficiency. Existing EU programmes will be assessed in the context of national experiences and needs.Core of the Concerted Action are three workshops each focussing on two participating countries, where national silvicultural and policy means will be analysed regarding: 1. Silvicultural management - Techniques applied or tested - Ecological/socioeconomic/technical contraints and requirements - Indicators for need/or mission of intervention - Key-criteria to evaluate success and efficiency of measures applied 2. National forest policy measures - Analysis of the policy process (background, objectives, etc.) - Link with other (e.g. EU) programmes - Organization, control of ou
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'How to break Mendel’s laws? The role of sexual conflict in the evolution of unusual transmission genetics' (PGErepro) targeting Horizon 2020.

assistant: **Abstract**

Under Mendelian inheritance, individuals receive one set of chromosomes from each of their parents, and transmit one set of these chromosomes at random to their offspring. Yet, in thousands of animals Mendel's laws are broken and the transmission of maternal and paternal alleles lose their symmetry. A large body of theory suggests that these asymmetries might arise because of maternal–paternal genetic conflict, but empirical tests are sorely needed to test whether the plausible is actual.This proposal aims to understand why, when and how the transmission of genes from one generation to the next deviates from Mendel’s laws. We ask how different types of sexual conflict -- both directly between parents (interlocus sexual conflict), indirectly between the parent’s genes within their offspring (intragenomic sexual conflict), and between genes expressed in males and females (intralocus sexual conflict) -- can affect the evolution of non-Mendelian reproduction. We focus on species with extreme reproductive asymmetry known as Paternal Genome Elimination (PGE). PGE males systematically transmit only those chromosomes that they inherited from their mother. This unusual reproductive strategy is thought to originate from a clash of interests between the sexes, where mothers have “won” by monopolizing the parentage of their sons. Although PGE is rarely studied, its repeated evolution and experimental tractability make it an ideal test case for understanding the role of sexual conflict in the evolution of genetic systems.


**Keywords:** sexual conflict,  transmission genetics,  sex determination,  entomology,  genomic imprinting, reproduction,  meiotic drive
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Astrocytes in Reward and their Bidirectional Relationship with the Dopaminergic System' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

Astrocytes are currently investigated in a range of questions extending far beyond their traditional 'housekeeping' functions. We have contributed to expanding the horizon of functions attributable to astrocytes, and have recently identified a novel and unexpected role for hippocampal astrocytes in signaling the location of reward. This pioneering ERC project, will drive considerable progress in an important and completely unknown facet of reward-related information processing: the roles of hippocampal astrocytes in signaling reward, and their interaction with dopamine, the main player in the reward system. In Aim 1 we will define the role of hippocampal astrocytes in the perception of reward. We will test whether astrocytes can encode the presences of reward irrespective of its location, based on non-spatial (auditory) cues. By simultaneously imaging both astrocytes and neurons, we will delineate the spatio-temporal interplay between them in reward representation, and examine the projection-specific effect of astrocytes in rewarded behavior. Work on Aim 2 will delineate the effects of the dopaminergic system on astrocytes. We will comprehensively analyse the distribution of dopamine receptors on astrocytes and the astrocytic response to tonic vs. phasic dopaminergic signals. We will also perform simultaneous imaging of dopamine levels and astrocyte Ca2+ dynamics in different behavioral states. Aim 3 will determine how astrocytes mediate the effects of the dopaminergic system. We will do that by manipulating astrocytic activity measure pre-synaptic dopamine axonal release in the hippocampus and its influence on the poorly understood phenomenon of over-representation of reward locations by neuronal place cells.Our published work and our new (unpublished) results generate
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Integrated Enabling Technologies for Efficient Electrical Personal Mobility' to be submitted under Seventh Framework.

assistant: **Abstract**

The P-MOB project is aiming at breaking the link between the growth in transport capacity and increased fatalities, congestion and pollution. Transport is responsible for 73% of total oil consumption in EU, it is a major source of pollution and greenhouse gas emissions and the chief sector driving future growth in world oil demand. Most continents have an increasing dependence from primary energy. The demand on increased safety, reduced noxious and green house emissions has the following expectations: less than 30.000 fatalities in EU in the 2010, radical reduction of both CO2 and NOx aiming at zero local emissions. Transport will be faced to the followings: People and good will increase their need of mobility some 35% per decade for at least 3-4 decades - The number of megalopolis is increasing and most of the traffic will be urban - Urban centers are more and more congested and closed to traffic; 1% of our GDP is wasted in congestion - Mobility is related to invariants such as: people move 1 hour a day - The average speed, since it has measured the first time in 1923, is stable in the range 35-40km/h - people tend to relate mobility to a mental freedom and as many as 90% of km are run with a single occupant - In EU 1 more million cars are on the road every 50 days and globally the number of vehicles is projected to 2200 millions in the 2050. The emerging markets require at most low cost and environment compatible vehicles. P-MOB addresses the above challenges proposing: a novel concept of fully electrical personal mobility, reduction of system complexity concentrating on the essentials, advanced systems integration including solar cells, e-motor and magnetic torque control of the wheel, power-energy management, distributed pack of accumulators, technologies to sell-bu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Effect of nano-patterned substrate properties on cell attachment and endocytosis' (2007-2013), addressing dissemination and exploitation.

assistant: **Impact**

Cell-substrate interactions have a pronounced effect on cell attachment, growth and proliferation in healthy tissues and disease. The complexity of the in vivo setting has fueled in vitro studies on different aspects of cell behavior in response to different material properties. The proposed research project aims at establishing links between substrate properties and the fundamental process of endocytosis, on which limited knowledge currently exists. The use of mechanically and chemically defined, nano-patterned surfaces to probe the cellular mechanisms of regulation of different internalization pathways will be achieved through use of specialized cargoes, fluorescent labeling and imaging techniques. Strong emphasis will be placed on cancer cells, where both derailed endocytosis and abnormal extracellular matrix contribute to the disease. The combination of the researcher’s strong background on endocytosis of nano structures and the host laboratory’s expertise on surface fabrication and cell-surface interactions guarantee implementation of the project. The anticipated results will have a pronounced impact on our understanding of this fundamental cell process and are likely to be of technological interest in the fields of drug delivery and tissue engineering in the near future.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Advanced manufacturing solutions tightly aligned with business needs' (AVANGARD), addressing dissemination and exploitation.

assistant: **Impact**

The AVANGARD project addresses the integration of three novel processing units into an existing Microfactory test bed conceived to produce urban electric vehicles. The units are state of-the-art multipurpose and multifunctional demonstrators on their own, specifically:Robotized integration of laser cutting-shaping-welding for 3D components Supersonic deposition of metallic powders for high speed 3D printing Large volume and high-speed 3D polymeric printingThe operation of the AVANGARD pilot will be demonstrated manufacturing I-Bikes, I-CARS and innovative battery packs.The proposed innovations target urban mobility where we are entering an era of rapid transformation and disruption which are also challenging traditional paradigms on manufacturing and business models characterized by an unprecedented speed, scale and scope of technological change.The project will prepare the environment for novel forms of collaborative distributed manufacturing amongst different EU regions. Innovative value chains will be pursued to overcome the scale (giga) and speed being established in planned economies (China) with market development controlled by the governments attitudes, targets and policy tools.To manage the IPRs and the supply chain, AVANGARD will implement a hybrid public-private Blockchain  platform where the public chain increases security through distributed consensus and validation and the private sidechain increases speed while keeping sensible data stored in the facilities of partners. The platform will allow auditability of sources, traceability, verification of sources, still with private control of documentation and compliance to data retention policies. The theme of Blockchain-powered manufacturing is relatively new. AVANGARD will address it with Ideas Forward PC, an
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Sixth Framework proposal on 'European Network of Funding Agencies - Coordination of National Complexity Research and Training Activities'.

assistant: **Innovation**

Complexity and complex systems is an emergent and rapidly growing research field with a large technological potential, in which Europe has fostered scientific excellence with extensive collaborations across Europe and abroad. Based on the need to put stronger focus on this field and to further its high growth potential, nine European Research Councils and Ministries initiated a consortium, in the form of a Specific Support Action, aiming to establish the necessary environment for coordinating nationally strategically planned research activities. The consortium has identified national research and training programmes which target or overlap on Complexity issues and established contacts with major Complexity research groups funded by the programmes and EU networks. The SSA has identified a significant need for better coordination of European activities in Complexity and Complex Systems and has demonstrated that good opportunities exist for exploiting the great growth potential there is for Complexity research. Our ambition is the formation of a nationally coordinated European setting on Complexity with the aim of further common use of experimental facilities, enhanced international training and mobility, supporting international scientific communications, promoting public dialogue and awareness, and catalysing innovation. The coordinated action proposed here is the work needed to establish this setting. The consortium will continue their collection and exchange of information and analyse and discuss the material to a level where a joint action plan can be formulated and agreed upon. The consortium also plans to expand its activities by inviting other countries, which were not part of the original SSA, to join in this proposal, thus broadening further Europes potential to
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Interfacial Electrochemistry of Carbon-based Interlayer in Lithium-metal Solid-state Batteries' (IECILSB) targeting Horizon Europe.

assistant: **Abstract**

Lithium-metal solid-state batteries (LMSSBs) are regarded as highly promising Post-Lithium-Ion Technology due to their high energy density and exceptional safety. However, their practical application remains challenging because of the interfacial issues at the metallic lithium|solid-state electrolyte interface (e.g., contact resistance and dendrite formation). In this regard, interlayer engineering based on carbon materials with different dimensions and fluorination degrees has been proposed to effectively address interfacial issues. Specifically, carbon quantum dots (0D), nanostripes (1D), and nanosheets (2D) will be used to clarify the influence of the geometric structure of carbon on the plating/stripping performance of lithium ions. Also, the fluorination degrees of carbon nanostructures will be precisely regulated to quantitively understand the fluorine chemistry-electrochemical performance relationships. Ultimately, this project will fill the knowledge gap in geometric design and chemical modification of carbon-based interlayer materials for developing safety LMSSBs with energy density > 500 Wh kg-1 and cycling life > 2000 times.


**Keywords:** Interface, Carbon interlayer,  Dendrite,  Lithium-metal,  Sold-state Batteries