RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Advanced Sample Preparation by Electrowetting Technology for MALDI Mass Spectrometry'.

assistant: **Innovation**

Matrix-Assisted Laser Desorption Ionization Mass Specrometry (MALDI-MS) is a leading analytical technology in detecting pathogens and biological molecules as DNA. It is also widely used for other applications as environmental, food safety or petrochemistry analysis, since it is an easy-to-use and easy-to-parallelize sample preparation. Despite all its advantages, the end-users demand for higher sensitivity, shorter operation times and more reproducible results. In order to overcome these drawbacks, we have developed a sample preparation device that can be integrated in every MALDI-MS instrument without extra modifications. In contrast to current passive technologies, eMALDI is based on a target plate with integrated electrodes that ensures homogeneous resides upon evaporation by electrowetting, resulting in intensified signals (100-fold boost), lower operation time (1-2s) and more reproducible results (30-60%). Its use can reduce a 57% the costs of the analytical centres. eMALDI BV was founded in 2012 and the technology has been internationally protected by patent. It has invested € 0.2 Mill so far, and has reached several agreements with venture capital firms. To successfully get eMALDI to the market we need to optimize the electrodes geometries and the plates´ coating, reduce the production costs, obtain the needed certifications and validate by the end-users. Also, we need to plan a set of activities devoted to dissemination and exploitation as trade fairs. The global market for eMALDI was € 0.4 billion in 2012. We plan to start our sales in Europe, so that by 2024 our turnover will reach € 12.5 Mill and a staff of 25 people.Therefore, we have decided to continue with ASAP-MALDI-MS project for what we need an additional investment of € 1.6 Mill, that considering a 5-
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Development of nano-spheres and quantum dots for electrochemiluminescent (ECL) biomedical diagnostic sensor technologies', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

This programme addresses how single molecules such as quantum dots or metal centres within nano-structured polyelectrolytes can be used to create efficient electrochemiluminescent (ECL) sensors multi-analyte detection, specifically for biomedical sensors with ultra-high sensitivities and selectivity’s. The unique capabilities of these novel nano-materials will arise from the coupling of photonic, chemical, optical and fouling resistant properties of each component to create a sensitive and selective detection system while allowing for applications in point of care devices.A combination of spectroscopic and electrochemical techniques will be utilised to elucidate the electron and/or energy transfer mechanisms, which will allow optimisation of device performance to be performed. The spectroscopic and electrochemical techniques highlight the redox reactions influencing the ECL production. Tailoring of surface properties and modification of polyelectrolytes will involve the use of several analytical techniques, including atomic force microscopy and electrochemical quartz crystal microbalance analysis. These studies focus on the binding of the polyelectrolyte, which will impart desirable surface chemistries at the material-solution interface to optimise the fouling resistant properties while retaining the sensitivity and selectivity of its ECL production for applications in imaging technologies.These materials will feed into product development which will incorporate sensor design, novel detection platforms and easy to use devices. The development of novel 2nd and 3rd generation materials will focus on the detection of cardiac Troponin I (TNI). The properties of these materials will uniquely enable the development of advanced diagnostic devices based on the luminescent detec
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Synchro-modal Supply Chain Eco-Net' (SYNCHRO-NET).

assistant: **Innovation**

SYNCHRO-NET will demonstrate how a powerful and innovative SYNCHRO-modal supply chain eco-NET can catalyse the uptake of the slow steaming concept and synchro-modality, guaranteeing cost-effective robust solutions that de-stress the supply chain to reduce emissions and costs for logistics operations while simultaneously increasing reliability and service levels for logistics users.The core of the SYNCHRO-NET solution will be an integrated optimisation and simulation eco-net, incorporating: real-time synchro-modal logistics optimisation (e-Freight-enabled);  slow steaming ship simulation & control systems; synchro-modal risk/benefit analysis statistical modelling; dynamic stakeholder impact assessment solution;  and a synchro-operability communications and governance architecture.Perhaps the most important output of SYNCHRO-NET will be the demonstration that slow steaming, coupled with synchro-modal logistics optimisation delivers amazing benefits to all stakeholders in the supply chain: massive reduction in emissions for shipping and land-based transport due to modal shift to greener modes AND optimised planning processes leading to reduced empty kms for trucks and fewer wasted repositioning movements.This will lead to lower costs for ALL stakeholders – shipping companies and logistics operators will benefit from massive reduction in fuel usage, faster turnaround times in ports & terminals and increased resource utilisation/efficiency. Customers and end users will have greater control of their supply chain, leading to more reliable replenishment activity and therefore reduced safety stocks and expensive warehousing. Authorities and governmental organisations will benefit from a smoother, more controlled flow of goods through busy terminals, and reduction of congestion o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Women travelling to seek abortion care in Europe: the impact of barriers to legal abortion on women living in countries with ostensibly liberal abortion laws' to be submitted under Horizon 2020.

assistant: **Abstract**

In many European countries with ostensibly liberal abortion laws, women face legal restrictions to abortion beyond the first trimester of pregnancy, as well as other barriers to legal abortion, in particular shortages of providers willing and able to offer abortion due to poor training and to conscientious objection among physicians. The Council of Europe has recognized that conscientious objection can make access to safe abortion more difficult or impossible, particularly in rural areas and for low income women, who are forced to travel far to seek abortion care, including abroad. The WHO also highlights that delaying abortion care increases risks for women’s reproductive health. Despite the relevance of this topic from a public health and human rights perspective, the impact of procedural and social barriers to legal abortion on women in countries with ostensibly liberal abortion laws has not been studied by social scientists in Europe. This five-year research project is envisaged as a ground-breaking multi-disciplinary, mixed-methods investigation that will fill this gap, by capitalizing on previous, pioneer anthropological research of the PI on abortion and conscientious objection. It will contribute to the anthropology of reproduction in Europe, and particularly to the existing literature on abortion, conscientious objection and the medicalization of reproduction, and to the international debate on gender inequalities and citizenship, by exploring how barriers to legal abortion are constructed and how women embody and challenge them in different countries, by travelling or seeking illegal abortion, as well as their conceptualizations of abortion and their self perception as moral/political subjects. The project will be carried out in France, Italy and Spain, where
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Case-based decision making - theory and applications' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

Research objectives and content The objective of the research project is two-fold. Principally, the recent idea of case-based decision making which combines case-based reasoning and decision theory should be developed further from a theoretical point of view. Moreover, the usefulness of this approach as a problem solving technique in artificial intelligence should be investigated. Particularly, the theoretical results obtained in the first part of the project should be used as a basis for the design of control structures for autonomous agents. Indeed, case-based decision making may provide a useful alternative theory of rationality and resource-bounded reasoning for (time/knowledge) limited agents. Training content (objective, benefit and expected impact) Within this research project I intend to specialize in the field of ,,uncertain reasoning and decision making' and to qualify further by doing the basic research for the so-called ,,Habilitation.' Particularly, I would like to learn about methods for utilizing case-based reasoning for decision making and about using fuzzy logic and decision theory as foundations of case-based reasoning. These questions concerning the relation of case-based reasoning, fuzzy logic, and decision theory are current research topics of the host group. Moreover, doing research in some different (especially foreign) scientific environment will contribute exceptionally to my experience and my future career. Links with industry / industrial relevance (22) The applicational part of the project will be worked on in cooperation with C-LAB (Cooperative Computing & Communication Laboratory), which is the joint R & D institute of the University of Paderborn and the Siemens Nixdorf Informationssysteme AG.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fifth Framework proposal on 'Statistical and regional dynamical downscaling of extremes for european regions'.

assistant: **Innovation**

For many EU countries, climatic change from whatever cause is most evident, part-circularly to the public & media, through changing frequencies of extremes. While there is a clear need for scenarios of extremes, such scenarios are not readily available at present, mainly because a systematic framework for identifying & evaluating suitable construction methods is lacking. STARDEX will provide such a framework through the rigorous & systematic inter-comparison & evaluation of statistical, dynamical & statistical-dynamical downscaling methods for the recon-striation of observed extremes & the construction of scenarios of extremes for European case-study regions. The more robust techniques will be identified & used to produce reliable & plausible future scenarios of extremes for the case- study regions for the end of the 21st century. These scenarios will help to address the vital question as to whether extremes will occur more frequently in the future.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Translational quantitative systems toxicology to improve the understanding of the safety of medicines - Sofia: 116030' (TransQST), addressing dissemination and exploitation.

assistant: **Impact**

TransQST will develop a Quantitative Systems Toxicology (QST) approach, employing pre-existing data where possible, in order to yield new mechanistic insight into drug-induced toxicity. A central tenet of our programme will be to ensure the human physiological and pharmacological relevance of any test system that has been (or will be) used for generating the input data for modelling. By adopting this approach, we will be able to accurately interpret what happens when test systems are perturbed by drug exposure, and ensure translatability of modelling tools. Mechanistic translational biomarkers are a core aspect of our approach and will be applied in parallel with evidence for understanding how to develop, model and apply such biomarkers in a QST setting. The project is structured in 8 work packages to provide the following outcomes: curate the best available experimental data suitable for modelling adverse drug reactions; provide fit-for-purpose QST models that will address key toxicity measures for liver, kidney, heart and GI-tract; provide quantitative risk assessment for off-target toxicity in man based on in vitro and in vivo models; provide a quantitative mechanistic read-across from species (in vivo and in vitro) currently used for the toxicological evaluation of a new drug; provide definition and applicability of the human physiological relevance of preclinical test systems; provide a battery of translational biomarkers that can be used for quantitative read-across from in vitro systems to man and which relate to intracellular pathways (and systems) relevant to drug toxicity. Led by the University of Liverpool, TransQST brings together 14 partners, characterized by their scientific rigour and proven track record. Collectively they will enable achievement of the g
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Software process improvement by model reuse' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

The introduction of information systems is carried out based on different phases. EBIT develops and introduces information systems for the power supplying industry. These systems are based on geographical information systems. There is an introduction process reaching from problem definition, situation analysis over business process modelling, software requirements analysis, selection of software, development and testing up to reorganisation and system operation. All steps are supported by well-known CASE-Tools. This software engineering practice shows one deficiency: Lack of reuse. Even though many of the projects are similar to previous ones, the steps are always carried out as for the first time. Therefore EBIT's current practice comprises potential for improvement in many factors such as costs and effort as well as quality. It's the objective of the experiment to improve the current practice, i.e. to reduce costs and effort and to improve quality. There are methods and tools on the market that could support model reuse. The quality will be improved by use of a standardised model, which will be applicable to customers with similar situation. Using reference models, developed with well-known methods and tools, will reduce costs and effort for the software engineering process. The objective is to reduce the costs for the introduction of net information systems especially for very small and small power supplying companies in Europe.THE EXPERIMENTThe requirements, methods and tools supporting model reuse should fulfil, will be analysed and defined. Information about methods and tools (e.g. the ARIS toolset of IDS Prof. Scheer GmbH) on the market that likely meet the requirements for the purpose of creating reference models will be collected. The methods will be evaluated
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Towards EXaflop applicaTions'.

assistant: **Objectives**

With top systems reaching the PFlop barrier, the next challenge is to understand how applications have to be implemented and be prepared for the ExaFlop target. Multicore chips are already here but will grow in the next decade to several hundreds of cores. Hundreds of thousands of nodes based on them will constitute the future exascale systems.<br/>TEXT is centered on the vision that the key component to support high productivity and efficient use of a system is the programming model, and we defend that MPI/SMPSs is a hybrid approach that can today be demonstrated and show the way to follow on the path to exascale. The SMPSs model provides the necessary support for asynchrony and heterogeneity as well as enabling incremental parallelization, modularity and portability of applications. By integrating it within MPI we can propagate its characteristics to the global application level. This is also a way to leverage and provide a smooth migration path for the huge number of applications today written in MPI.<br/>The focus of the TEXT project is to install the MPI/SMPSs environment at several HPC facilities of partners and demonstrate how seven real and relevant applications/libraries can be improved using it. The codes fall in the areas of basic linear algebra libraries, geophysics, plasma physics, engineering and molecular dynamics. They have been selected considering  the impact in their respective scientific communities.<br/>We will actually validate our claim by evaluating the ported applications with different end users and collect their feedback to further improve the technology. We will also promote the use of the model to other application developers beyond what is feasible to integrate as committed project partners.<br/>In order to exploit the opportunity window an
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Models, Assessment, and Policies for Sustainability'.

assistant: **Innovation**

MAPS aims to broaden the range of policies, models, and assessments to help achieve sustainability, equity, and human well-being.The lack of evidence for sufficient absolute decoupling between economic growth and environmental pressures suggests that future trajectories built on economic growth may not be possible. There is an urgent need for a new paradigm that reconciles human well-being with environmental sustainability -- one based on a “post-growth” approach. The idea is that high-income countries should move beyond the pursuit of GDP growth as a policy goal, and instead pursue policies that improve human well-being while reducing resource use.Despite increasing interest in this idea, the main integrated assessment models (IAMs) used in climate mitigation modelling do not consider post-growth policies or scenarios. MAPS has the ambition to expand the range of policy options available to policymakers and incorporate post-growth scenarios into the major scientific assessments of the IPCC and IPBES. Our goal is to provide new approaches to help steer Europe and the world back within planetary boundaries without compromising on valuable social welfare goals.To this end, MAPS will use participatory processes to develop new policy packages and scenarios, and then assess these policies using a state-of-the-art simulation model. In particular, it will estimate the resource use requirements of a good life, design social welfare systems that are growth-resilient, incorporate a broader range of environmental and social indicators into assessment models, and explore how alternative policies could be implemented in practice.MAPS will provide knowledge about policies that reduce resource use to be within planetary boundaries while maintaining or improving social outcomes. In so