RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'A Reference System Architecture and Technology Platform for the Shipping Sector' (ARETOPS).

assistant: **Innovation**

The aim of the ARETOPS project is to create a shipping sector specific reference architecture and to use it for the development of an open technology platform supporting the integration of key IST services/applications for the shipping industry. A strong user group will guide the proposed research and development work programme and results will be deployed and evaluated in six pilots. The outcome will be shared in the public interest and policy recommendations will be made.Objectives:ARETOPS aims to facilitate e-business solutions in the shipping sector. It will form the basis for an automated system linking information providers for navigational use and ship management, and data from ship controls systems to the integrated ship-office computer. The project will develop a Reference System Architecture and an Integration Platform. The Reference System Architecture will be broad enough to support strategic tactical and operational shipping processes. It will cover all the shipboard systems including integrated navigation and engine monitoring and control and it is flexible to accommodate future business requirements. The Integration Platform will consist of a core integration component and three standard interfaces, i.e., the Shipping Applications Interface, the Ship Sensors Interface and the Shipping Information services Interface.Work description:The project will start by reviewing the requirements for quality and efficiency in shipping processes and consequently the integration/ interoperability requirements for shipping IT systems. A Shipping Reference Architecture will be designed to meet these requirements. The project will prototype an integration platform to realise the reference architecture and demonstrate the integration of selected applications (both shipboard
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Streamlining Geo mapping and Early Monitoring with an All-in-One Data Collection System for power line and mining industries' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

Power line and mining industries face challenges related to vegetation encroachmentand infrastructure monitoring. The inefficient monitoring of vegetation growth near power lines increases the risk of wildfires, while inadequate monitoring of mining infrastructure can lead to safety hazards and operational inefficiencies. The current solutions are often inefficient due to their high operational costs, time-consumption and low-quality output, since most of them are custom built for the specific application of end user.Therefore, by combining advanced sensor fusion technology and real-time monitoring AISPECO innovation IMC Aerie, offers a comprehensive and cost-efficient solution. The system's controller allows integration of various sensors, creating a live Digital Twin enabling efficient vegetation management and infrastructure integrity eliminating wildfire and slopes sliding risks offering safety improved operational efficiency. It follows principles of digitalization and implements Industry 5.0 standards, European Green Deal- reducing GHG & black carbon emissions, and contributes to SDGs.


**Keywords:** Sensor-fusion, Digital Twin, Real-time Inspection, LiDAR, Hyperspectral Imaging Edge-computing, Power lines management, Rail infrastructure, Network infrastructures, Energy Efficiency, Forestry, Envir
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'IMaging Pancreatic Alpha-cells Calcium Tied with HEterogeneous Analysis of Labeled Transcription factors with in situ Hybridization'.

assistant: **Concept**

Excess of plasma glucagon is frequently reported in diabetic patients, a misregulation that exacerbates hyperglycemia, a major complication of diabetes. This has spurred research into alpha-cell function and glucagon regulation, to find potential treatments, independent from insulin, for diabetes. To normalize glucagon secretion as a therapeutic strategy, it is crucial to have a better understanding of its regulatory mechanisms and the expression of specific genes regulating those mechanisms. Unfortunately, there is no consensus model explaining the regulation of glucagon secretion from pancreatic alpha-cells. However, calcium is known to be required for glucagon secretion, but its role is not completely understood.  We propose to evaluate the role of free calcium activity across islet α-cells in the regulation of glucagon secretion from mice, using a custom built light-sheet fluorescence microscope, allowing fast three-dimensional imaging for an extended amount of time.  The interest will be focused on the heterogeneity of the response, which forms subpopulations of α-cells. After, the attention will be addressed in discovering cellular expression patterns of transcription factors known to be relevant in alpha-cells through immunofluorescence, and to determine how these regulate their target genes using single molecule Fluorescence In Situ Hybridization (smFISH). Particular attention will be focused on correlating the heterogeneities of calcium activity in subpopulations of alpha-cells with their differential gene expression.By finding this differential expression, it will be possible to target specific genes in order to trigger various single-cells behaviors and discover novel therapeutic targets.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'The Role of the RPL11/p53 Checkpoint in the Development and Treatment of DBA', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Extensive studies have demonstrated that the underlying cause of Diamond Blackfan anemia (DBA) is hypomorphic mutations in ribosomal protein (rp) genes. Patients with this disease present with an erythroid anemia, which has the propensity to progress to a wide range of cancers, particularly acute myeloid leukemia and osteosarcomas. Recently our laboratory has provided a model to explain the anemia, and, potentially the cancer. We first showed that after disruption of either 40S, or 60S ribosome biogenesis, p53 levels increase due to the binding of rpL11, a 60Srp, to HDm2, leading to a G1cell cycle arrest. However, in the case of 40S, but not 60S ribosome biogenesis, this response requires the translational upregulation of rpL11, to generate sufficient protein to bind to HDm2, in the face of continued 60S ribosome biogenesis. In parallel, it is known that rp genes, including rpL11, are direct transcriptional targets of c-Myc, a master regulator of cell proliferation and differentiation, and that rpL11 acts in a negative feedback loop to block c-Myc target genes. In preliminary studies we find that rpL11 controls c-Myc transcription. These studies have led us to hypothesize that a complex containing rpL11, is upregulated in response to disruption of 40S ribosome biogenesis, to induce p53 cell cycle arrest and suppress c-Myc expression, preventing tumor progression. Likewise loss of this checkpoint could explain the propensity of DBA patients to progress to cancer. To address the first part of this hypothesis, the role of rpL11 in anemia, we have designed three aims (1) To identify the signaling components involved in the upregulation of rpL11 (2) To determine the mechanism of rpL11 induced inhibition of HDm2 in response to disruption of ribosome biogenesis and (3) Develop
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Obtainment of panels and other wooden and plastic accessoires from recycled paper and cardboards through a semi-dry process' to be submitted under Fifth Framework.

assistant: **Abstract**

The aim of the project is to study and to realise a process to transform paper and the discarded paper of the industries into panels, plastic and other material for furniture or other industries. With this project, a no-water recycling system will be made whose output will be some material for the furniture or plastic industries, ready to be used for furnishing with no need for other processing. The project answer to the requirements of a new European set of rules about sustainable growth. These rules concern mainly with defence and reformation of environmental goods: water is one of the most precious and important natural resource. The project reduces the use of wood and plastic for the furniture industry and increases the use of recycled paper. This is an important aspect, indeed all the European countries have a lot of difficulties in the recycle of paper, because recycling is difficult, expensive and needs a lot of water.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Just and effective governance for accelerating wind energy' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

JustWind4All aims to support the acceleration of on- and offshore wind energy through just and effective governance, i.e., the creation of synergies among people and organisations to coordinate and participate in actions around wind energy strategies and deployment. To this end, JustWind4All develops knowledge, practical guidelines, instruments, strategies, and trainings for just and effective decision-making in on- and offshore wind energy governance. This move towards more effective and just decision-making processes and structures is crucial in the context of ambitious EU renewable energy targets, which require installing more and larger on- and offshore wind farms, speeding up the planning and deployment processes whilst ensuring no one is left behind. JustWind4All makes use of a rigorous trans- and interdisciplinary multi-method research design. It combines holistic impact assessment based on a social-ecological approach with techno-economic modelling to assess a variety of social, environmental, technical, and economic impacts and/or benefits to improve decision-making. Qualitative and quantitative methodologies (e.g., case studies, multicriteria mapping) help to investigate ways to foster wind energy citizenship with a particular focus on participation, energy justice and social innovation. Through transdisciplinary knowledge co-production in Wind Labs, JustWind4All makes the most out of novel resources i.e., practices (repowering), technologies (airborne, floating) and regions (e.g., Bulgaria) and engages in knowledge co-production with wind energy governance actors for fit-for-purpose outcomes. A cutting-edge Wind Forum network enables knowledge exchange and dialogue between multiple stakeholders across policy, community, market and third sector – it ensures th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Development of a metacarpo-phalangeal joint prosthesis' (1994-1998).

assistant: **Concept**

Rheumatic alterations of the joints in the hand is one of the main reasons for limited mobility and functional loss of the joints in the hand. The affected joints lead to serious disability throughout Europe. Surgical replacement of the affected jont by a prosthetic joint can restore its natural function and mobility. Up to the present there is no adequeatly fucntioning metacarpo-phalangeal joint prosthesis available to the medical community to remedy this problem. The objective of this project is to develop a metacarpo-phalangeal joint prosthesis that allows a natural mobility and fuction of the hand and has a lifetime of at least ten years. To optimize durability and fuction of the prosthesis recent scientific results for adequete fixation of the prosthesis and newly developed techniques to reduce wear of the artificial joint sufaces will be applied
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Design Driven Innovation For SMEs' (DesignShots) under Horizon 2020.

assistant: **Objectives**

Design is a key driver in creating new products and services that are attractive to customers, and can make a business stand out among the competition. However, the lack of design management skills is a significant barrier to the wider adoption and integration of design into Europe’s businesses. As stated in the Innovation Union Flagship Initiative, although some European countries are world leaders in design, others lack a robust design infrastructure and design capability. This systemic gap has largely gone unnoticed but must now be tackled. Innovation agencies should tackle this gap by supporting and promoting design driven innovation programmes and services. The overall aim of Design Shots project is to  use the experience, the tools, the capacity and the partners’ knowledge in order to address a common innovation support challenge namely to promote the integration of design driven innovation to smes through the creation of tailor made “design driven innovation support programmes” for private sector. The Peer learning activity will serve to learn from the best and to share good and bad practices in design driven innovation support services for smes. The realized Design Options Paper will serve as a “guide” or a “handbook” to other agencies and business support centres to provide similar and/or more focused services/support/ programmes on design driven innovation.


**Keywords:** Design, Innovation, Support
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'PORTable Innovation Open Network for Efficiency and Emissions Reduction Solutions' in the context of a Horizon 2020 call.

assistant: **Objectives**

PIONEERS brings together four ports with different characteristics, but shared commitments towards meeting the Green Deal goals and Blue Growth socio-economic aims, in order to address the challenge for European ports of reducing GHG emissions while remaining competitive. In order to achieve these ambitions, the Ports of Antwerp-Bruges, Barcelona, Venlo and Constanta will implement green port innovation demonstrations across four main pillars: clean energy production and supply, sustainable port design, modal shift and flows optimization, and digital transformation. Actions include: renewable energy generation and deployment of electric, hydrogen and methanol vehicles; building and heating networks retrofit for energy efficiency and implementation of circular economy approaches in infrastructure works; together with deployment of digital platforms (utilising AI and 5G technologies) to promote modal shift of passengers and freight, ensure optimised vehicle, vessel and container movements and allocations, and facilitate vehicle automation. These demonstrations form integrated packages aligned with other linked activities of the ports and their neighbouring city communities. Forming an Open Innovation Network for exchange, the ports, technology and support partners will progress through project phases of innovation demonstration, scale-up and co-transferability. Rigorous innovation and transfer processes will address technology evaluation and business case development for exploitation, as well as creating the institutional, regulatory and financial frameworks for green ports to flourish from technical innovation pilots to widespread solutions. These processes will inform and be undertaken in parallel with masterplan development and refinement, providing a Master Plan and r
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Play to learn: ludic video games and interactive experiences to improve critical and computational thinking skills' to be submitted under Horizon Europe.

assistant: **Abstract**

This project investigates the use of primarily ludic video games and interactive experiences aimed at transferring skills within the Critical and Computational Thinking skill sets – e.g., literacy, numeracy – using gameplay as opposed to presentation. This niche of products is under-researched, compressed between serious games and purely ludic games, and suffers from a lack of systematic design and evaluation guidelines. The main objective is to define a framework of design and evaluation principles for the development of video games and interactive experiences with education and skill transfer in mind, and to explore the role of ludic technologies in education. I will design, develop, and experimentally evaluate a series of video games and interactive experiences based on specific skills drawn from the Critical and Computation Thinking skill sets. I will engage with domain experts in the chosen skills to identify the best ways of transferring these skills through gameplay. The design process and evaluation methodologies will contribute to the the definition of a framework of design and evaluation principles (main objective) which I will publish at the end of the project. Throughout the project, I will publish results from the individual design and experimental phases. I will create a network of industrial partners – i.e., video game developers, museums and cultural institutions – for commercial exploitation and potential future collaboration. This project is relevant because it addresses the social problem of improving numeracy and literacy skills through the frameworks of Critical and Computational Thinking, which is part of the EU’s policy in the field of adult learning. The use of ludic video games and interactive experiences broadens the target audience to include
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Design of Novel Portable-Sensors Based on Suspension Arrays Composed of Monoclonal Antibody andBacteriophage Carrying Magnetically Loaded Nanoparticles and Surface Enhanced Raman Spectroscopy' (NanoBacterphageSERS) targeting Seventh Framework.

assistant: **Abstract**

In this project, we aim to develop nanotechnology-based systems for detection of pathogenic bacteria in several aqueous media mainly in environmental water based on suspension arrays together with a portable custom-designed detection system. The six objectives (six work packages) are as follows: (i) Nanostructured sensors surfaces, in which electron-beam, photo-, soft and dip-pen lithographies will be applied in the fabrication of functionalized low-cost (disposable) SERS substrates, specially designed for simultaneus Raman and Fluorescence enhancement; (ii) nanosorbents and their mixtures as suspension arrays against the target bacteria for capturing units in which firstly magnetically loaded nanoparticles will be produced and labelled/barcoaded with fluorosence dies and/or quantum dots and then bacteriophages, monoclonal antibodies, and/or aptamers will be immobilized onto these nanoparticles as bioligands to recognize and capture the target bacteria specifically; their mixtures will form the suspension arrays; (iii) target bacteria and bacteriophages; the target bacteria (as water pollutants), are Escherichia coli, Enterococcus species and Bacteroides ovatus; bacteriophages which will recognize these bacteria will be selected/produced as bioligands;  (iv) aptamers; they will be selected/modified/produced; (v) sensors/array systems; a portable “Raman Spectrometer/Fluorescence Detector System” will be designed/produced that will be used together with the nanostructured sensors platforms, and finally (vi) validation; the materials and systems developed will be validated. This is a multidisciplinary and technological project and therefore brings together experts from different disciplines both from academia and industry. Basicly, the knowledge that will be developed/ acc