RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Methodological Excellence in Data-Driven Approaches to Linguistics'.

assistant: **Objectives**

The MEDAL consortium project has the ambition to reduce the recognised gap in access to expertise, training and research funding in Linguistics across Europe through a horizontal, network approach to engaging a new generation of researchers in empirically grounded, up-to-the-minute methodology. The consortium, comprising four highly acclaimed research organisations (Widening country member and coordinator, the University of Tartu, Estonia; Max Planck Institute for Psycholinguistics in Nijmegen & Donders Institute at Radboud University, both in the Netherlands; University of Birmingham, UK) who will jointly lead a concerted move to increase the global competitiveness of Linguistics in Europe by bringing together world-class pioneers and early-career researchers, developing excellence in methodological training, and formulating a model of international collaboration on cross-linguistic, cross-modal, cross-disciplinary research. The project focusses on three clusters of empirically grounded methods which inform state-of-the-art language research: corpus studies, experimental methods, and computational modelling. The consortium will launch a multi-pronged effort to build better methodological expertise and awareness among the next generation of researchers, offer high-level training schools in the methods included in the project, and engage in the project’s collaborative Gold MEDAL Research project, in which early career researchers gain first-hand experience in conceptualising and designing a multi-method research programme, implementing it across a range of languages and modalities, and disseminating the results, leading to increased visibility for all partners. By 2025, the MEDAL consortium will have developed internal expertise, established a sustainable joint training
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Improved bio-traceability of unintended microorganisms and their substances in food and feed chains', explaining its relevance to EU policy priorities under Sixth Framework.

assistant: **Impact**

Food Safety policy within the EU is governed by the White Paper on Food Safety (Comm 199, 719 Final) which calls for a comprehensive integrated approach to ensure a high level of human health and consumer protection. This policy has been enacted into legislation by The General Food Law of Jan 1st 2006 (178/2002). This legislation places responsibility for traceability on the food/feed producer (Section 4, Articles 18-20). The strategic objective of BIOTRACER IP is to improve traceability of microorganisms ( biotraceability) contaminating the food/feed chain (including bottled water), whether accidental or deliberate. Using a total food chain approach, we will develop recommendations to control any risk through integration of novel genomic and metabolimic data resulting in a better understanding of the physiology of the microorganisms, combining these with advances in predictive food-based microbiological models.The BIOTRACER IP Consortium consists of 47 partners, including Europe's largest food/feed industries, several SMEs, relevant INCO countries and networks. The consortium includes experts in predictive microbiology, database developers, software companies, risk assessors, risk managers, system biologists, food and molecular microbiologists, legislative of ficers, standardization and validation members and food retailers. The work is planned for 4 years and is organised in 5 Research Areas, including 10 projects. The practical work is organized in 20 cross-disciplinary workpackages, covering tracing and tracking of contamination in feed, meat and dairy chains, in addition to accidental and deliberate contamination of bottled water. The results of the project will ensure a more reliable and rapid response to a contamination event.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'WATER RESOURCES VULNERABILITY TO CLIMATE AND ANTHROPOGENIC LANDSCAPE CHANGES'.

assistant: **Innovation**

Climate projections and trend analysis of historical data suggest that precipitation and temperature changes can dramatically alter the supply of and the demand for water in the human- and eco-systems. Moreover, anthropogenic landscape changes are occurring at unprecedented scales and rates given the societal needs for various (and often competing) ecosystem goods and services (food, energy, and water).  How stable or resilient are the human- and eco- systems to climatic and anthropogenic perturbations remain a major societal concern. Of these concerns, hydrologic cycle changes, water resources availability and related management rank among the highest because of their importance in regulating human and ecological sustainability and climate feedbacks. A number of recent studies suggest that continental runoff increased throughout the 20th century despite a rapid increase in water consumption by humans and their activities. Scope of the project: The goal of this research program is on the overall impact of such changes on rainfall (the source of water) and concomitant replenishment of usable water supplies (e.g. ground- and stream- water) given their high priority to any future water resource planning.  Even within this restricted scope, the barriers to scientific progress are numerous necessitating an inter-disciplinary approach that combines principles from eco-hydrology, hydraulics and fluid mechanics, soil physics, plant physiology, stochastic processes, dynamical systems theory, and water resources management. This project aims to build a network of researchers with complementary talents to begin progress on these fronts. Moreover, this network of researchers will be actively engaged in preparing the next generation of international scientists (via graduate student
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'RNA functions in parasite-host communication in the gut' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Cross-species communication is required for proper functioning of the mammalian gut, where different organisms share resources, coordinate digestion and maintain homeostasis. In many animals, parasitic worms (helminths) are part of this ecosystem, where they communicate through the release of bio-active molecules that promote immunological tolerance and modulate gut functions. Mechanisms of cross-species communication are still not well understood and my lab discovered that ribonucleic acids (RNA) are one of the products helminths release to directly influence host cells. The overall goal of RNACOM is to determine how gastrointestinal parasites use this novel form of RNA communication to regulate the gut epithelium and to develop strategies to block the communication mechanism during infection.  We have recently discovered a specific Argonaute protein that gastrointestinal nematodes use to transmit parasite RNAs to mouse cells. We will target this protein to identify parasite-host RNA-RNA interactions that occur during chronic infection (Aim 1). We will then determine the specificity and function of parasite RNA transmission to mouse cells in the epithelium using model organoids and in vivo imaging (Aim 2) and will determine the mechanism of action of parasite RNAs in host gene suppression using synthetic and recombinant strategies (Aim 3). Finally we use genetic tools in the mouse model to determine the function of cross-species RNA-RNA interactions during infection, while testing new strategies to block RNA transmission by the parasite (Aim 4).   RNACOM will bring key quantitative and molecular understanding to the processes by which RNA from one species can influence another, advancing a frontier area in RNA biology while testing new strategies of parasite control. I
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Bottom-Up Nanomachines' under Fifth Framework.

assistant: **Concept**

Starting from the electronic and mechanical properties of single molecules on surfaces, we will design, synthesise and test molecular devices like molecular wires, molecular 3-terminal gates and intramolecular circuits. Nano-technology and chemistry are both developed to fabricate the interconnection nano-circuit with a fault tolerant specific architecture, the molecular interconnects and the cantilevers for a parallel assembly of those devices on the circuit. 7 groups from 6 different countries are participating to this project, 4 in UHV-STM and/or UHV-STM-AFM, 1 in theory and chemistry, 1 in nano-fabrication and one in circuit and processor architecture.OBJECTIVESBUN will design, synthesise, interconnect, assemble and test molecular devices (with critical dimension well below 1 nm) and circuits to build an information processing machine in a bottom up approach. Tunnelling electrons are used as information carriers guided by atomic and atomic wires through molecular circuits associated to form a real space fault tolerant architecture as opposed to quantum computer state space" concepts. Molecular 3-terminal gates will be designed, tested and integrated along those circuits. BUN will provide the fabrication processes for the metallic and dielectric interconnections, for the parallel deposition and positioning techniques of the molecular devices or the elementary molecular processor on the circuit interconnection network.DESCRIPTION OF WORKTo gain a fine knowledge on the inter and intramolecular electronics and mechanical behaviours of single molecules on surfaces, intensive UHV-STM and UHV-STM-AFM studied are carried out using all the I-Z, I-V, I-X, F-X and F-Z spectroscopy accessible on a single molecule with those techniques. This is re-enforced by a unique STM and AF
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Coupling biogeochemical analysis, environmental DNA and ecological network analysis of sediment cores to reconstruct environmental history and ecosystem changes in Posidonia oceanica meadows.' under Horizon Europe.

assistant: **Concept**

POSIDONIArXiv combines multiple disciplines to reconstruct ecosystem processes, dynamics and change through time in Posidonia oceanica meadows in Spain. P. oceanica is an iconic seagrass in the Mediterranean Basin, forming extensive meadows and dense mats which work to stabilise sediments and form a millenary sedimentary archive while providing habitat for an abundance of marine life. P. oceanica meadows contribute to global change mitigation and adaptation by sequestering pollutants including CO2, and reducing coastal erosion, while enhancing biodiversity by providing habitat and breeding areas for marine life including commercial species. However, seagrasses in general and P. oceanica in particular, are in decline due to anthropogenic disturbances such as climate change, pollution and land-use change. These meadows sustain the livelihoods of coastal populations and are located in coastal areas throughout the Mediterranean. In particular, P. oceanica inhabits sheltered embayments that also constitute key areas of settlement by ancient civilisations until present. POSIDONIArXiv combines environmental DNA, biogeochemical analysis and ecological network analysis to understand the historical changes in P.oceanica meadows. Firstly, sediment cores will collected at sites of high and low anthropogenic disturbance and biogeochemical analysis will be conducted to determine key periods of human or natural disturbance. This will inform sampling and eDNA analysis to reconstructed historical changes in biodiversity at these sites. Furthermore, the eDNA data will be used for ecological network analysis over millennia timescales to understand biodiversity change and identify mechanisms of resilience in this environment. Overall, POSIDONIArXiv will strengthen management and restoratio
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Mechanistic insights into protein degradation by Lon, a AAA+ protease' under Seventh Framework.

assistant: **Concept**

Background: AAA+ proteases are ubiquitous molecular machines that execute regulated protein degradation in cells. Their activity is necessary for regulation of many cellular processes, as well as to clear the cell of misfolded, potentially harmful proteins. Failure to combat protein unfolding in unicellular organisms often leads to reduced viability, and in humans, accumulation of misfolded proteins may result in prion diseases, cancer and neurodegenerative disorders. Conserved in bacteria and eukaryotic organelles, the major enzyme responsible for degrading damaged proteins is a hexameric AAA+ protease known as Lon. Despite its central role in most living organisms, the mechanism of substrate degradation by this protease is poorly understood. Objectives & Work Plan: To reveal the detailed molecular mechanism of protein degradation by Lon and related AAA+ proteases by studying the Lon protease of Escherichia coli as a model system. The research will exploit the fact that Lon is the only AAA+ protease for which a natural protein inhibitor – PinA, a T4-bacteriophage protein – is known. Genetic screens will be conducted for the isolation of Lon mutants with improved mechanistic properties that result in faster substrate processing, and for active mutants that are resistant to PinA inhibition (aim 1). To obtain insight into the mechanistic properties of the mutants, biochemical characterization will be carried out using native and unfolded protein substrates, a wide variety of peptide substrates, and sensitive assays for the detection of binding and degradation (aim 2). To solve the 3D structure of Lon, primary crystallization screens will be set-up to optimize the crystallization conditions so as to obtain crystals that diffract at high resolution (aim 3). Relevance to Wor
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'BiG DAta for SmarT SociEty'.

assistant: **Objectives**

GATE aims to establish a BiG DAta for SmarT SociEty Center of Excellence in Bulgaria, in order to provide focus for increased scientific excellence and sustained Big Data growth, through attractive and stimulating research environment, advanced infrastructure supporting open innovation and vibrant ecosystem to enable responsive research and innovation. GATE Center of Excellence  will be fully autonomous and purpose-built institute, established as a joint initiative between Sofia University - the most prestigious educational and scientific hub in Bulgaria, Chalmers University of Technology, Sweden - outstanding European institution with extensive experience in research, education and innovation in Big Data area and Foundation Chalmers Industrial Technology, Sweden  a leader in innovation management, university-industry collaboration and technology transfer. GATE is a timely initiative that is fully exploiting the opportunities created by the innovation ecosystem boost and the Big Data market pull in Bulgaria, the Artificial Intelligence technological push in Sweden and the EU and global research and development urge for Big Data. The CoE will deliver economic and societal benefits through training data professionals and fostering closer collaboration between academia, government and industry, thus helping Bulgarian organisations and industry in various sectors to become, and remain, competitive. Being the only Big Data CoE to be established in Eastern Europe, GATE will bridge the gap between the 55 centres in Western Europe and Eastern Europe and will play a strategic role for disseminating the best practices and innovative models to the widening countries.


**Keywords:** Big Data, Explainable Artificial Intelligence, Machine Learning, Semantic Technologies, Real-time D
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Memory in Times of Crisis: Argentina, Spain and Greece, 1998 to now'.

assistant: **Concept**

MeTC examines how people in networked societies recall the recent past (ReP) in times of economic recession through the lens of social media (SoM). It explores the connections between crises and memory politics by investigating Facebook, Instagram, and internet forums in Argentina, Spain, and Greece (ASG) – three countries which transitioned to democracy between 1974 and 1982 and experienced optimism and prosperity in the proceeding years before they suffered from economic crises. MeTC is a comparative, interdisciplinary historical and digital-ethnographic project which links two methods of digital ethnography (invisible observation; immersive cohabitation) with oral history and intermedial and multimodal analysis. The project aims to: a) analyse memories of the ReP during crises in SoM in ASG; b) employ its own SoM to trigger discussions on the relationships between the present and the ReP on the basis of stimuli gathered through archival research; c) scrutinise the politics of these SoM-driven mnemonic communities through oral interviews from people engaged in the formation of the politics of digital collective memory in ASG. MeTC provides an adaptable model for how historians and media scholars can turn embarrassment in the face of the SoM-driven explosion of amateur historical storytelling on the web into a source of inspiration and a channel of communication among these two communities of scholars and the public. Drawing on the host’s interdisciplinary capacity and synergies with experts in ASG, MeTC promises to provide a bold academic and social impact in these ways: a) publication in journals, and the delivery of a hybrid workshop and seminars; b) interaction with popular audiences through SoM, a photo exhibition and open public speaking events organised with imm
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'SMART MICROBIOME-BASED PLATFORM FOR THE EARLY DETECTION OF BIOLOGICAL THREATS IN AGRICULTURE', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Biome Makers is an innovative biotech company founded in 2015 by two well-recognized Spanish entrepreneurs, based in both Spain (14 employees) and U.S. (6 employees). We were named one of the Most Innovative Startups at the AgFunder Innovation Awards and Worldwide Agripreneur of 2019 in the future Agro Challenge. By combining DNA Sequencing technologies to profile the whole spectrum of microbes populating in the soils and proprietary Artificial Intelligence, we are using ecological computing algorithms to understand this complex network of microorganisms. The final goal is to provide insights and innovative metrics measuring soil bioactivity to improve agricultural yields and lower its environmental impact. Biome Makers have developed the first patented smart soil microbiome-based platform with a unique database of more than 5,000 soil samples from 20 different countries worldwide. In this context, BeCrop® rises as an innovative product that will provide a detailed snapshot of the health status of crop soils, by giving metrics about crop diseases risks, general biodiversity, an nutritional shortcomings, through the identification of the whole soil microbiome (the known +67K microbial species but also the unknown) with only a soil sample per ha. BeCrop® is the direct evolution of our system WineSeq®, developed by Biome Makers. WineSeq® is the first and the only intelligent platform designed for the wine sector for the characterization and comparison of the microbial communities that influence the quality and the organoleptic properties of wine, through a genomic NGS tool. In this context, the development of BeCrop® relies on the need to develop a complete soil microbiome diagnosis and microbial interactions understanding to identify potential microbial biomarkers to meas