RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Two Isotopes for Neutrinoless double beta decaY search' (TINY).

assistant: **Innovation**

The TINY experiment will focus on the investigation of neutrinoless double beta decay (0n2b) with 96Zr and 150Nd isotopes. The search for 0n2b is a hot topic in particle physics, as the discovery of this rare nuclear process would establish the Majorana nature of neutrino, fix the neutrino mass scale, and prove lepton number non-conservation, setting the grounds for new physics beyond the Standard Model. The current and near-future large-scale searches for 0n2b do not include the nuclei chosen for the TINY project, due to the unavailability of an appropriate scalable detector technology for these candidates. Both 96Zr and 150Nd have the crucial advantage of very high transition energy for the 0n2b process, which would allow obtaining a higher sensitivity to the effective Majorana mass compared to other isotope candidates. Bolometric detectors with high energy resolution and active particle identification will be developed during the project execution. 96Zr will be embedded into ZrO2 crystals, measured with thermal sensors and coupled to auxiliary light detectors for active alpha particles rejection. 150Nd will be studied with magnetic NdGaO3 absorbers and athermal phonon sensors. Particle identification will be achieved via pulse shape discrimination. The first ever efficient measurement of a magnetic compound as a bolometer will open the way to new opportunities in low-temperature particle detection. The TINY pilot experiment, consisting of a-few-kg scale underground demonstrator, will be able to set the best limits worldwide on the 0n2b half-lives for both 96Zr and 150Nd isotopes. Very low background in the region of interest will be obtained thanks to high transition energy and alpha rejection.  Not only will this project be competitive in the international context o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Hybrid dry–hot Extremes prediction and AdapTation' under Horizon Europe.

assistant: **Concept**

Half a million people die due to heat stress every year. These numbers keep rising as climate continues to change. Heatwaves are becoming more frequent and severe, and disproportionally synchronised with droughts. Droughts reduce the ability of the land surface to cool down via evaporation, further enhancing heatwave temperatures. Nonetheless, how these compound drought–heatwave events spatially propagate, and their future lethality, remains unclear. Counterintuitive findings now indicate that drought can even dampen heatwave deadliness by reducing air humidity.Consequently, our ability to forecast dry–hot events and their impacts on human health remains limited. Subseasonal timescales, between two weeks and two months, have traditionally been a blind spot: conventional weather forecast models are not tailored to these scales. However, the adoption of Artificial Intelligence (AI) may hold the key to fill this gap and reliably predict the upcoming occurrence of heat stress episodes weeks in advance. This would bring enormous societal benefits by enabling emergency planning. In this project, we will explore an innovative way to generate subseasonal forecasts of droughts and heatwaves, and their consequent human heat stress episodes. A 'hybrid' approach will be embraced, i.e., an approach based on physics-based models combined with AI algorithms. Building upon this approach, we will deepen our understanding of the climatic drivers of human heat stress, and explore the future benefits of land-based adaptation practices designed to attenuate these events, including afforestation, crop selection, and large-scale irrigation. Altogether, HEAT will foster our preparedness and resilience to future heat stress episodes – by improving their prediction, investigating the mechanisms
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Japan and Europe Network for Neutrino and Intensity Frontier Experimental Research 3' (JENNIFER3) targeting Horizon Europe.

assistant: **Abstract**

JENNIFER3 aims to continue, further develop and finalize the research and communication activities started in 2015 within the JENNIFER project and currently being carried on by the JENNIFER2 MSCA-RISE project, which will conclude in may 2025. The community forming the JENNIFER3 consortium is putting together three research programs at experimental facilities located in Japan where very rare processes can be observed:  accelerator produced neutrinos (T2K and HyperK collaborations), cosmic neutrinos detection (HyperK collaboration) and a high luminosity electron-positron collider (Belle II experiment at SUPERKEKB). Such programs use different approaches, are sensitive to different “messengers” of the new physics world and are essential to complement the so called “energy frontier” investigation which is carried on at the LHC. Sinergy and knowledge sharing among them is the drive force of the JENNIFER3 project, which on one hand fosters the collaboration of European scientists with the Japanese research community, while on the other hand promotes close collaboration among different European research groups around key technologies, such as cloud computing and data network developments, machine learning applications for data filtering and reconstruction, photon detection, solid state detectors, particle beam monitors. Collaboration with private sector technology providers is also essential to reach the scientific objectives of the project. All project members are also committed to disseminate and communicate their work to the scientific community and to the European society through various initiatives aiming to different targets.Cross fertilization between different research communities and approaches is the real added value to boost the project  impact, both in terms of sci
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Mechanochemistry: a unique opportunity for oxygen isotopic labelling and NMR spectroscopy' (MISOTOP) targeting Horizon 2020.

assistant: **Abstract**

Oxygen is an element of major importance, due to its presence in the vast majority of molecules and materials. Over the years, much effort has been put into the development of analytical techniques allowing the study of oxygen environments, in view of elucidating key questions about the structure and reactivity of a variety of systems. In this context, Nuclear Magnetic Resonance (NMR) spectroscopy has been the focus of much attention, because it has progressively emerged as a technique capable of providing deep insight into the local structure around this atom. However, NMR spectroscopy is highly challenging for oxygen, mainly because the NMR-active isotope, oxygen-17, has a very low natural abundance (0.04%), and hence a very poor sensitivity. Because of this, the majority of 17O NMR studies require enriching the molecules and materials of interest in 17O. Unfortunately, 17O-labelling is simply unaffordable at the moment for most research groups, meaning that 17O NMR spectroscopy is inaccessible to the broad community, and still considered as an “exotic” tool of analysis.            In this ERC project, the goal is to develop new rapid, user-friendly, and low-cost protocols for enriching a wide variety of organic and inorganic compounds in 17O by using mechanosynthesis. This original approach will then be taken as a unique opportunity (i) to push the current boundaries of 17O solid state NMR spectroscopy (by developing new tools for studying the structure of complex molecular and materials systems), and (ii) to elucidate major questions which could not be addressed so far, especially concerning reaction mechanisms between solids and the structure of interfaces of biological relevance.            In doing so, the overall idea is to make 17O NMR spectroscopy become a mor
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Single cell tracking of malignant transformation in GATA2 deficiency' (2014-2020) targeting Horizon 2020.

assistant: **Abstract**

Precision medicine has improved overall survival of cancer patients; unfortunately, not all diseases can benefit from this practice due to a scarce understanding of their molecular mechanisms. This is the case of GATA2 deficiency, a complex multi-system disorder characterized by bone marrow failure, immunodeficiency and high risk to develop myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). Chemotherapy and allogenic hematopoietic stem cell (HSC) transplantation are the only available treatments, underlining the lack of predictive tools as a clear medical need.Penetrance and expressivity within GATA2 families is often variable, suggesting that cooperating somatic mutations and epigenetic events are required to trigger the disease. Here I propose to unravel the molecular mechanisms of malignant progression of GATA2 deficiency by combining single cell multi-OMICs approaches with groundbreaking functional assays in human induced pluripotent stem cells (hiPSCs). First, to identify pathogenic single nucleotide variations and small insertion-deletions, I will perform an integrative analysis combining whole exome sequencing with whole-genome bisulfite sequencing to analyze the methylation status genome wide on 15 well-annotated GATA2 carriers. Then, I will model the stepwise progression of normal cells to MDS through the sequential introduction of recurrent GATA2 mutations and known second driver mutations in hiPSCs by CRISPR/Cas9 genome editing. The hiPSC-derived hematopoietic progenitors will be used for simultaneous profiling of transcriptome and chromatin accessibility at single cell resolution to decipher the underlying gene regulatory networks among the different genetic backgrounds.A thorough understanding of the genetic and epigenetic features of GATA2 ca
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Public Protection and Disaster Relief – Transformation Center' (PPDR-TC), addressing dissemination and exploitation.

assistant: **Impact**

A significant amount of network capacity needs to be available throughout the disaster and affected areas to support effective Public Protection and Disaster Relief (PPDR) communications where mobility is the main requirement.  At the very early response stages voice communications are critical, after which non-voice communications are an important requirement dependent on the nature of the disaster.As most mobile telecommunications networks located in a disaster area are designed to support normal traffic loads, they will not have the capacity to provide effective PPDR communications. As disasters require effective co-ordination, support and communication between all agencies involved, it would be ideal if one communication solution could be provided to meet all needs.  Radio communications networks used by public safety and the emergency services will normally be used to provide Public Protection.  Most public safety organisations have the capability to rapidly deploy mobile communications network elements to provide additional capacity and/or maintain communications if the main network fails. As the trend in parts of Europe is to allow non-public safety organisations that could be involved in major emergencies and disasters to operate on the same networks as used by public safety organisations, it is reasonable that provision could be made on these networks to Disaster Relief (DR) agencies.The goal of PPDR-TC is to specify an interoperable, secure and resilient voice and data communications architecture, tailored specifically for the needs of the PPDR community. It will provide the foundation for the evolution of mission critical communications. PPDR-TC will address both mission critical and non-mission critical situations in an integrated and uniform way. Enable ubi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Molecular biology of cell wall regeneration in L-form bacteria' (Regenerate) targeting Seventh Framework.

assistant: **Abstract**

Cell wall deficient (L-form) bacteria are thought to be important in various resistant, persistent or chronic infections. L-form cells are highly abnormal in size and shape and are sensitive to osmotic shock but highly resistant to antibiotics that work on the cell wall (e.g. penicillins and cephalosporins). How these unusual cells arise and how they proliferate in the absence of a wall, is poorly understood. The Errington lab recently developed a model system for studying this long standing problem in the tractable model bacterium Bacillus subtilis. A key element of L-form biology that awaits further investigation lies in how these cells revert to the walled state. This reversion or regeneration requires the resumption of cell wall synthesis and the reacquisition of the normal regular rod cell shape. Regeneration is presumably important for the resumption of disease in patients with persistent or recurrent infections. Therefore, blocking regeneration might offer a way of dealing with problem infections. A better understanding of the mechanisms of regeneration might also be important for various biotechnological applications. The aims of this proposal are as follows. First, to use state of the art imaging methods to characterise the poorly understood regeneration process. Second, to attempt to identify mutations that prevent or enhance the rate of regeneration, and characterise the genes affected, so as to understand the process better. The genes identified might provide novel targets for drugs to target persistence. Finally to explore the extent to which regeneration of L-forms can be exploited as a novel vehicle for efficient transformation or genome transplantation processes.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'VINEyardROBOT' (VINEROBOT).

assistant: **Innovation**

The aim of this project is the design, development, and deployment of a novel use-case agricultural robot under the scope of Unmanned Ground Vehicles (UGV), and equipped with several non-invasive sensing technologies to monitor: 1) of grape yield, 2) vegetative growth, 3) Water stress and 4) Grape composition in order to optimize the vineyard management and improve grape composition and wine quality.<br/>The use of UGVs to monitor vineyard physiological parameters and grape composition has several advantages over simple hand-held devices for manual sampling and over UAV.<br/>UGVs may provide key information regarding vineyard physiology and water stress, grape composition, and pests and diseases' incidence much faster than manual solutions and at higher resolution, in a more flexible way, and lower cost than aerial scouting carried out by drones or planes.<br/>The scope covers the integral monitoring of vineyards, over the entire season, by placing a ground robot along the vineyards (endowed with artificial intelligence and machine learning techniques).The final users will receive updated in mobile application (app).<br/>The proposed use-case agricultural robots (where key proximal sensing technologies will be implemented) will allow revolutionary and conclusive decision making to optimize vineyard management and to drive agronomical fundamental decisions according to grape yield estimation, plant growth monitoring, water status, and berry composition assessment. UGV proposed will incorporate an integrated system that includes machine vision, thermography and fluorescence-based sensors. Canopy images and data acquisition processes will be executed in real time through customized algorithms to compose specific production maps.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'From Black Soldier Fly to Green Chitin and Bioplastics: A novel value chain within insect-based circular economy', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Commercial insect production for food and feed is a fast-growing industry. Among different insect species, Black Soldier Flies (BSF) show promising potential due to their efficient bioresource recycling capability and high nutritional values for animal feed applications. In addition, they are an important source of chitin, the second most abundant polymer after cellulose in the world, with diverse industrial applications. The current insect production sector has primarily overlooked the application of chitin, mainly focusing on products associated with nutritional values. However, in the future commercial insect sector will generate a lot of wastes, including dead fly and pupae exuviae. This project aims to provide industrial value to the dead fly and pupae exuviae of BSF industry into chitin and bioplastics, developing and exploiting novel, efficient, and environment-friendly approaches. This is because, from 1950-2015, the world has already generated 6.3 billion MT of plastic, and an estimated 12 billion MT of plastic is predicted to reach landfills by 2050. These plastics slowly disintegrate to generate Micro-Plastics harming life underwater and above land. Thus, we must develop bio-based plastics to replace the heavy use of harmful plastics. This project will extract the chitin from insect by-products and develop it into bioplastics. The current chitin extraction involves the usage of harsh chemicals leading to severe environmental pollution. Therefore, green techniques are needed to extract chitin from these insects. This study will refine and employ cutting edge techniques to extract chitin from BSF. The chitin produced will be suitable for developing bioplastics since the biomass used to make bioplastic will be biodegradable and is not food product. This would be
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Delivering Agile Research Excellence on European e-Infrastructures' in the context of a Horizon 2020 call.

assistant: **Objectives**

DARE (Delivering Agile Research Excellence on European e-Infrastructures) aims to provide scientific communities with a unifying hyper-platform and development context to allow for user-friendly and reproducible carrying out of huge data-driven experiments, and rapid prototyping. DARE specifically addresses the requirements of innovating teams of research developers and scientists, who work on the intersection of software engineering and scientific domains, and on data, complexity and computing extremes.The size and complexity of scientific data, as well as the difficulty in formulating domain-specific solutions in reproducible and reusable ways, may often lead to throw-away, unsustainable end-user products, or long release cycles. This complexity increases exponentially with the size and diversity of input and produced data. Furthermore, widely used big-data technologies and analytics, while they are known to lead to increased productivity in commercial settings, they are often not taken advantage of in scientific. The requirement to deal with diverse exascale data resources dictates the need to ensure and increase productivity through the controlled disruption of the current modus operandi of European RIs. DARE aims to be the technological pivot for this transition, while providing transparent, traceable and developer-friendly bridges over existing infrastructures and services.Building on extensive experience in research e-infrastructures, semantification and the handling of metadata, and on big-data technologies and domain applications, DARE will equip teams of innovators with meaningful abstractions and tools allowing for rapid prototyping of reproducible and efficient research solutions. DARE will improve further and integrate tried and tested programmatic dataflow