RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Platform for envIRonmentallY Sustainable Textile processing, to be replicated worldwide in the fashion industry Feasibility Study' in the context of a Horizon 2020 call.

assistant: **Objectives**

Textile finishing, imparting specific effects on the garments, is currently relying on practices considered as borderline or phased out by the environmental regulations and REACH restrictions. Fashion big names are leading the development of a greener chemistry, not compromising on the final aesthetics.SPYRIT project is aimed to apply Nearchimica skills to develop knowledge – intensive solutions to textile finishing, combining in innovative way laser, ozone, chemical, resins and enzymes processing, into targeted recipes. The results demonstrate the achievement of final effects on garments, granting at the same time lower environmental impact, energy and time expenditure.  The added value is the long-standing expertise of Nearchimica, and the availability of a complete set of technologies, unlocking green growth potential, at the same performances level of the current processing. SPYRIT aims to cut environmental footprint more than 50%, in terms of LCA, providing to Nearchimica primary role in the supply of fine chemicals and in process consultancy to textile industry.Technological Feasibility Assessment, LCA verification of the effective sustainability, and the Business Models project objectives permit to unlock a real blue ocean of new opportunities in the sector.Nearchimica is an Italian company, dealing with the formulation, production and commercialization of chemicals for the textile industry, which mission is to provide customers with products responding to their needs under different aspects: performance, regulatory, ecological, cost effectiveness. In the latest 10 years, Nearchimica launched lines tailored to a reduced environmental footprint, sustainability, responding in advance to the REACH and safety issues.Nearchimica Business Model is fully aligned with th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Exploring Gender in Children's Literature from Cognitive Corpus Stylistic Perspective' in the context of a Horizon 2020 call.

assistant: **Objectives**

Gender equality remains a critical societal challenge. But how does one ‘learn’ gender? Children’s literature presents one early source of cultural norms, values and assumptions about gender. Language use in these texts is a crucial means by which children learn about gendered concepts and behaviours. To understand this formative influence more deeply, the innovative GLARE project will examine the discursive construction of gender in corpora of English children’s literature drawing on a novel cognitive corpus stylistic approach to characterization to conceptualise the notion of gender. GLARE will further take a diachronic perspective to the development of gender representation over time. The ‘cognitive corpus stylistics’ links together corpus linguistics (CL) and Cognitive Poetics (CP). CL methods combine qualitative and quantitative approaches to text analysis while CP offers a theoretical framework to account for the creation of meaning in the mind of the reader. The approach adopted by GLARE stresses that the representation of real and fictional people is related – in terms of the background knowledge that readers bring to texts and in terms of the patterns used in a text. Hence, relationships between the representation of fictional characters and real people are to some extent a reflection of links between patterns in fictional and non-fictional texts. To investigate this relationship, the project draws on complementary data from the Times Digital Archive. Through the description and analysis of linguistic patterns GLARE will provide novel insights into the way in which children’s literature can influence the creation of gendered concepts and behaviours. GLARE will be situated at the University of Birmingham and supervised by Prof. Michaela Mahlberg, a world-leading
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Wheat and barley Legacy for Breeding Improvement'.

assistant: **Objectives**

WHEALBI will combine genomics, genetics and agronomy to improve European wheat and barley production in competitive and sustainable cropping systems. Germplasm representing the species diversity will be selected and characterised in unprecedented detail by next-generation-sequencing. Life history and adaptive traits will be evaluated in both transnational field experiments and a state-of-the-art precision phenotyping platform. Germplasm will be stored in a specialised and accessible bio-repository and associated data in knowledge bases that will represent a valuable legacy to the community. Whole genome association scans will be conducted for several traits, signatures of adaptive selection will be explored, and allele mining of candidate genes will reveal new variation associated with specific phenotypes. Pre-breeding tools and pipelines will be developed to optimize the efficiency of allele transfer from unadapted germplasm into elite breeding lines. New methodologies will explore how to optimally exploit the large amount of new genotypic and phenotypic data available. They will focus on the design of ideotypes with improved yield stability and tolerance to biotic and climatic stresses and provide proof of concept of the efficiency of genome and phenome assisted selection. Ideotypes and reference varieties will be evaluated in innovative cropping systems, particularly organic farming and no-till agriculture, and an economic evaluation of these approaches will be conducted. The results will be disseminated to a broad user community, highlighting the benefits and issues associated with the adoption of what is considered sustainable and environmentally friendly wheat and barley crop production in a European context. WHEALBI aims to help the EU remain a major actor in wor
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Next Generation Machine Intelligence for Medical Image Representation and Analysis' (MIRA), addressing dissemination and exploitation.

assistant: **Impact**

Machines capable of analysing and interpreting medical scans with super-human performance would transform healthcare as much as medical imaging itself did over the last century. With an increasing complexity and volume of data the interpretation of images and extraction of clinically useful information push human abilities to the limit. There is high risk that critical patterns of disease go undetected. We require powerful and trustworthy computational tools based on machine intelligence to support experts and go beyond human performance to tackle the major challenges in clinical practice. Two key ingredients are currently missing: 1) interpretable statistical representations that capture important information while reducing complexity; 2) intelligent algorithms that leverage knowledge across multiple tasks to solve the most challenging problems such as early detection of pathology.This project is devoted to redefine the state-of-the-art in medical image analysis by developing a new generation of machine intelligence using powerful techniques of representation learning. Key to the project is its unique access to some of the largest and most comprehensive imaging databases combined with world-leading expertise in machine learning and medical imaging. An overarching objective is to harvest information from population data to construct what will be the most advanced statistical models of anatomy. In contrast to previous attempts that focus primarily on specific organs or pathology, here shared representations are learned from highly complex data by jointly solving multiple tasks. Linking the representations with demographics, lifestyle, genetics and disease allows probing of genetic and environmental determinants related to specific anatomical and pathological phenotypes a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'CONCERTED ACTION SUPPORTING THE TRANSPOSITION AND IMPLEMENTATION OF DIRECTIVE 2018/2001/EC ON THE PROMOTION OF THE USE OF ENERGY FROM RENEWABLE SOURCES (RECAST)' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

The Concerted Action supports the implementation of the RES directive. In particular, the Concerted Action facilitates sharing experience and good practice of implementation, finding common approaches as well as cross-learning and cooperation. The work carried out within the CA-RES is designed to meet the needs of RES Directive implementing organisations. The action will provide added value compared with measures taken by each MS acting on its own. The Concerted Action will help make knowledge available to all participants through access to a network of national experts engaged in implementation of the Directive. The CA-RES4 will do this through a structured framework that will facilitate the exchange of information and experience through a series of meetings and other communication tools. It will provide participants with an opportunity to learn from others implementation process and policy approaches and build national policy capacity, but also to explore opportunities for bi-lateral or multi-lateral cooperation and identify areas for possible future convergence and harmonised approaches amongst participating countries.  The CA-RES4 builds upon the success and structures of the previous phases of the CA. The CA-RES community has developed during the course of the previous phases into a unique network of experts and will be strengthened. The objective is to provide participating countries with the most pertinent information that may lead them on the most efficient path towards an effective implementation of the RES Directive 2018/2001/EC in the EU. The expected impact of the Action consists of a more harmonized approach and improved implementation of the RED II in participating countries, a strengthened network of experts as well as the transfer of good practices betwe
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Exploring Functional and Developmental Osteoclast Heterogeneity in Health and Disease' (EUROCLAST).

assistant: **Concept**

Euroclast proposes a research training program on osteoclast biology in the context of osteoclast-driven diseases. Osteoclasts are the complex, multinuclear cells responsible for bone breakdown. Many diseases of osteoclast malfunctioning manifest in bone loss, for example, osteoporosis, cancer-induced bone disease, periodontitis, or rheumatoid arthritis, all conditions set to increase in an ageing EU population. The Euroclast consortium (7 academic, 2 private and 1 ass. partner) focuses on osteoclast heterogeneity, a recent insight that poses new fundamental questions best tackled by a multi-partner consortium capable of assembling the sophisticated molecular, genetic and imaging tools required. We will analyze changes in gene and protein expression during osteoclast (trans)differentiation from different precursor cell pools and in various bone sites and relate this to osteoclast activity and sensitivity to therapeutics. The osteoclast resorptiveapparatus will be studied using in depth and will define the key enzymatic and molecular machinery to be translated into novel site-specific drug targets or biomarkers. High throughput screening assays for therapeutics and ELISAs for biomarkers will be developed with our private partners. Our multidisciplinary and cross-sectorial approach will improve understanding and treatment of common disorders associated with osteoclast malfunction and train 11 early stage researchers (ESRs) in modern cell and bone biology. We will provide extensive training in generic skills and all ESRs will spend time with our private partners and be seconded to other academic partners to ensure they are well equipped for employment in research and industrial settings. Euroclast will produce an on-line repository for osteoclast protocols, make methodolog
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'CCL18 - a susceptibility gene for atopic eczema regulated by host-microbe interactions?' will create measurable scientific, societal and economic impact aligned with Sixth Framework.

assistant: **Impact**

Atopic disorders are a group of increasingly common multifactorial chronic diseases, which cause inflammatory and degenerative changes in the skin and mucosal surfaces. Among those diseases, atopic eczema represents the most prevalent condition affecting u p to 22% of the paediatric and 1-3% of adult population.The aetiology of atopic eczema involves environmental, genetic and immunological factors. For the prevention and treatment of this disease, advances are needed in the identification of susceptibility factors, disease markers and therapeutic targets. The skin-specific trafficking of inflammatory cells during atopic eczema is regulated by chemokines. CCL18 is the most highly and specifically expressed chemokine in atopic eczema.We will analyze the role of single nucleotide polymorphisms in the CCL18 gene in the susceptibility for atopic eczema using an exceptional size of DNA sample collection (n = 3111) obtained from atopic and non-atopic individuals. Furthermore, we will analyze the methylation status of CCL18 gene in atopic eczema patients in comparison to healthy controls.Additionally, we will examine whether the serum level of CCL18 correlates with disease severity, therapeutic treatments and trigger factors, using large number of well-characterize d samples obtained from atopic eczema patients and healthy individuals. The host's previous work demonstrated an important role for the opportunistic yeast Malassezia in triggering the IgE- and T cell-mediated inflammation in atopic eczema patients.Hence, we will investigate whether Malassezia allergens can be responsible for the elevated level of CCL18 in atopic lesional skin by examining CCL18 expression in all relevant structural cells of the skin as well as in dendritic cells and mast cells.This project aims to
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'EOPEN: opEn interOperable Platform for unified access and analysis of Earth observatioN data' (EOPEN) targeting Horizon 2020.

assistant: **Abstract**

Earth Observation data access through the Copernicus data distributor systems has paved the way to monitor changes on Earth, using Sentinel data. One of the main objectives of EOPEN is to fuse Sentinel data with multiple, heterogeneous and big data sources, to improve the monitoring capabilities of the future EO downstream sector. Additionally, the involvement of mature ICT solutions in the Earth Observation sector shall address major challenges in effectively handling and disseminating Copernicus-related information to the wider user community, beyond the EU borders. To achieve the aforementioned goals, EOPEN will fuse Copernicus big data content with other observations from non-EO data, such as weather, environmental and social media information, aiming at interactive, real-time and user-friendly visualisations and decisions from early warning notifications. The fusion is also done at the semantic level, to provide reasoning mechanisms and interoperable solutions, through the semantic linking of information. Processing of large streams of data is based on open-source and scalable algorithms in change detection, event detection, data clustering, which are built on High Performance Computing infrastructures. Alongside this enhanced data fusion, a new innovative, overarching Joint Decision & Information Governance architecture will be combined with the technical solution to assist decision making and visual analytics in EOPEN. Apart from EO product-oriented data management activities, EOPEN also exploits user-oriented feedback, tagging, tracking of interactions with other EOPEN users. EOPEN will be demonstrated in real use case scenarios in flood risk monitoring, food security and climate change monitoring.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Understanding the Gene Regulatory Network involved inner ear Hair Cell differentiation' (GRNHairCell) targeting Horizon 2020.

assistant: **Abstract**

What is the molecular basis for transcription factor (TF) specificity in different developmental contexts? This question is central to our understanding of development, and key to the development of effective regenerative therapies. My model system is the inner ear hair cell (HC), essential to hearing and balance. Very little is known about the genetic networks regulating HC development. To gain new insights, I developed during my PhD a new transcriptional programming strategy to promote in vitro HC differentiation, starting from pluripotent stem cells. In vivo Atoh1 is the only TF known to be necessary and sufficient for HC differentiation, but in vitro its overexpression induces neuronal rather than HC differentiation., I discovered that Atoh1 expression combined with two other TFs (Pou4f3, Gfi1) resulted in efficient HC generation. This work offers a new paradigm to understand the molecular mechanisms governing TF specificity in an important biomedical context. For example, how do Pou4f3/Gfi1 modulate Atoh1 activity to orchestrate a HC differentiation program? To address this question, I will exploit multiple approaches, such as genome-wide studies (RNA-seq and ChIP-Seq), bioinformatics analysis, in vitro stem cell differentiation systems and in vivo mouse models. The knowledge gained will help us to discover the causes behind the lack of HC regeneration in mammals, will inform therapeutic strategies to protect or replace HCs, and will uncover general principles by which the same TF can direct distinct cell fates.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'To-Euro-5G:  Supporting the European 5G Initiative' to be submitted under Horizon 2020.

assistant: **Abstract**

The To-Euro-5G project has a clear objective to support the activities of the European 5G Initiative as outlined in the 5G contractual Public Private Partnership (cPPP) during the second phase of the 5G-PPP from June 2017 to June 2019, with the intention of maximising the return on this investment for Europe..    The objectives of To-Euro-5G include: •Progressing the 5G-PPP high level goal of maintaining and enhancing the competitiveness of the European ICT industry, and seeking European leadership in the 5G domain. •Supporting activities where the 5G-PPP can contribute to the implementation of the European 5G Action Plan . •Assembling an overview of the 5G-PPP projects trial/demo/showcase potential and encouraging any organisation performing such an activity to identify the “European 5G” basis of their public showcases.•Responsibility for orchestrating the cross project activities of the 5G-PPP projects selected for Phase 2 of the 5G-PPP, as foreseen by Article 41.4 of their respective grant agreements, for example, in the areas of Standards, Spectrum, Architecture, management, Security and a number of other key strategic aspects of 5G. •Developing and implementing a strategic communications plan, including technical and social media channels, to ensure the best possible impact is achieved with the results of the 5G-PPP projects and the horizontal activities of the 5G-PPP programme. •Stimulating, organising and hosting strategic events and workshops where the European 5G achievements will be promoted on a global level.•Orchestrating an open, transparent and flexible 5G-PPP programme governance structure that facilitates good co-operation between the projects, the commission and the 5G Infrastructure Association..The To-Euro-5G project also has the underlying ambition t