RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'A molecular atlas of Actin filament IDentities in the cell motility machinery' (ActinID), addressing dissemination and exploitation.

assistant: **Impact**

The actin cytoskeleton is essential to cellular function and hence to life. It is regulated not only via a complex synergistic and competitive interplay between actin-binding proteins (ABP), but also by filament biochemistry and filament geometry. Both the biochemical identity of an actin filament as well as the geometrical identity of actin networks are defined by ABP activity, while biochemistry and geometry also regulate ABP recruitment. However, it is still unknown how actin filament biochemistry, geometry and ABP activity jointly define actin cytoskeleton remodelling in a dynamic system such as cell migration. Resolving this critical relationship would enable a better understanding of the multitude of cellular processes that ultimately depend on actin.ActinID will tackle this question by advancing in situ structural biology to generate a molecular atlas of the actin cytoskeleton proteome in migratory cell protrusions. Our overarching aims are to:1) Develop: cryo-electron tomography workflows to achieve 3D imaging of entire actin networks in cellular protrusions at single-filament resolution, combined with detailed quantitative analysis. This will provide the ground truth on how dynamic filament geometries steer directional cell movement.2) Solve: high-resolution in situ structures of ABPs and F-actin and describe ABP quantity, ABP distribution and spatial correlation with their potential partners. This visual proteome will reveal how actin filament identities are regulated in an entire system.3) Study: the reciprocal regulation of ABP activity, filament geometry and biochemistry via (genetic) manipulation of ABPs using integrative cell and structural biology experiments, and relate this to cell migration characteristics.ActinID will be transformative for our unders
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Autonomous robotics and digital TWIN to improve water network performances' in the context of a Horizon Europe call.

assistant: **Objectives**

Our project aims to revolutionize the water industry through the development and commercialization of an innovative robotic inspection system. Our robotic inspection system offers a comprehensive set of functionalities that enable water utilities to gain deep insights into the condition of their water pipelines. With the ability to autonomously navigate inside the pipeline, our system conducts detailed assessments of the structural integrity, identifies leaks, and analyses the quality of the drinking water. By developing the Digital Twin of the water networks, our technology empowers water utilities to make informed decisions and take proactive measures to ensure the reliability, efficiency, and safety of their water networks.At the core of our business model is Robotics as a Service (RaaS), which offers a flexible and cost-effective solution for water utilities. Instead of incurring substantial upfront costs, water utilities can access our cutting-edge technology on a subscription basis. This model eliminates the financial barriers to entry and allows utilities to benefit from the latest advancements in robotic inspection without compromising their budgetary constraints. With a strong focus on sustainability, our robotic inspection system aligns with several Sustainable Development Goals (SDGs), including SDG 6 (Clean Water and Sanitation) and SDG 9 (Industry, Innovation, and Infrastructure). During 2025-2029, our robotic inspection system will preserve 143 million cubic metres of drinking water; these savings correspond to the annual consumption of 2.6 million EU citizens. This greatly aligns with global efforts for sustainable water management and environmental preservation.


**Keywords:** Water pipeline inspection, digital twin, Non Destructive Testing, in-line rob
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Fully Recyclable A-PET (FRA-PET): a sustainable and cost-effective oxygen barrier food packaging' (FRA-PET) targeting Horizon 2020.

assistant: **Abstract**

Each year, over 381 million tonnes of plastic waste are produced worldwide - equivalent to the mass of two-thirds of the world population. Around 13 million tonnes of this plastics end up in the oceans, causing serious threat to the environment and global health, and an economic burden of €7 billion per year globally. This global emergency calls for new solutions to increase plastic recycling rate. About 14% of the global plastic waste is represented by food packaging. PolyEthylene Terephthalate (PET) is the most common plastic resin used in the food packaging industry. To increase food shelf life, PET is commonly combined with other chemicals, such as EVOH, to create multilayer PET/EVOH plastic sheets that offer an efficient barrier to oxygen penetration to the plastic food tray. While representing a need for food quality preservation, the presence of an EVOH layer makes food plastic trays not recyclable. Unfortunately, since PET/EVOH trays cannot be sorted from fully recyclable PET trays (i.e., those not containing EVOH), they cause all the food trays to be discarded rather than recycled – accounting for 1.1 million of  tonnes of PET trays either incinerated or landfilled each year only in Europe. Point Plastic offers FRA-PET, a game-changing additive to produce fully recyclable PET barrier package for food preservation. Thanks to additive proprietary chemical formulation, FRA-PET food trays provide the highest efficiency oxygen barrier and best performance in food quality preservation without requiring EVOH use. FRA-PET enables to increase the current recycling of plastic barrier food trays from 0% to 100%, sustaining the circular economy of plastic.  FRA-PET has the potential to become the new gold standard for PET packaging.The key objectives of the project are to
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Non-Classical Correlations and Entanglement in Twin-Atom Beams' (CORENT).

assistant: **Innovation**

Quantum atom optics aims at performing with atoms similar experiments to that performed in quantum optics with photons. The motivation for doing so is twofold. From a fundamental point of view, we wish to demonstrate that non-classical correlations and entanglement exist also for massive particles and behave as predicted by quantum theory. From a more practical point of view, such properties also represent the central resource for quantum computing and a tool to increase the sensitivity of atom interferometers. Yet atoms are much more difficult to manipulate than photons because of their coupling to the environment and there is a long way to go until quantum atom optics catches up with quantum optics.This proposal investigates a new route towards this goal as it focuses on pairs of atoms with an entangled momentum state, in sharp contrast with the vast majority of quantum atom optics experiments so far, which relied on the internal degrees of freedom. More precisely, the research project proposes to generate two atomic beams in a two-mode squeezed state and to probe the entanglement by means of a Mach–Zehnder-like interferometric measurement. In this setup, the spatially separated twin-atom beams will be recombined onto a beam splitter and the two output ports will be monitored by a single-atom detector. The analysis of correlations between the atom number at each port will allow us demonstrating the presence of entanglement. Using mechanical degrees of freedom, we will closely follow the reasoning put forward by Einstein, Podolsky and Rosen, and we be able to demonstrate entanglement in the most “classical” situation.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'The sources of historical signal in the genomes of birds' in the context of a Horizon 2020 call.

assistant: **Objectives**

Genome-scale sequence data play an important role across the biological, medical, and agricultural sciences for extracting the signatures of divergence among species and populations. Multiple basic biological forces influence the evolutionary information content of genomes, leading to substantial variation across genomic loci and lineages. Models of molecular evolution for phylogenomics are routinely used for extracting information about evolutionary history, and ultimately for making inferences of the relationships and amount of evolutionary change among taxa. However, existing phylogenomic methods are not amenable for identifying the impact of specific drivers of historical information across whole genomes. The present action will develop tests in the framework of model adequacy for assessing the impact of the primary evolutionary forces on the genome. Assessment of model adequacy proceeds by comparing simulated data under a given evolutionary model with empirical data. The novel framework will be tailored at whole-genome analysis. It will allow a comprehensive examination of the sources information signal left by basic evolutionary forces, such as speciation, mutation, selection, recombination, and drift. The new methods will be disseminated through an intuitive software package that will be openly available for researchers across biological sciences. Examining the sources of evolutionary information will allow improved phylogenetic inferences and guide model improvement. An unparalleled genomic resource of the genomes of every avian family, soon to be released by the host, will be examined in detail with the methods developed. This will provide insights into genome evolution in birds and inferences of their evolutionary history with unprecedented confidence.


**Key
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Deprotonation of organic molecules in solution by ab-initio MD and rare events simulation techniques' (SIMDEPRO) under Seventh Framework.

assistant: **Objectives**

Deprotonation of organic molecules are key processes involved in the rate limiting step of many chemical and biological processes. Their reaction mechanism depends on several factors such as the nature of the acid functional group (carboxyl, hydroxyl, etc.), the substituents of the molecule, and the type of solvent. However, despite their importance, the mechanism of these processes remain not well understood.In this project we shall study the mechanism of deprotonation of different classes of organic molecules in different solvents by ab-initio simulations, elucidating also the role of the solvent and molecular substituents. Standard atomistic simulations techniques, such as molecular dynamics (MD), cannot be used for simulating these processes by brute-force because of the time scale involved:  deprotonation is a rare event. This problem will be overcame using modern 'sampling' techniques, such as Temperature Accelerated Molecular Dynamics, the String Method, and  Milestoning, adapting them to the study of deprotonation process and, more generally, to chemical reactions. These techniques allow to compute the reaction rate, characterize its mechanism(s), and calculate its free energy along the reaction path (i.e. free energy barrier) of chemical reactions in realistic  conditions (i.e. in solution).The present project will require expertise in both electronic structure calculations  in condensed phase, of which the proposer is an expert, and statistical mechanics in which the scientist in charge (Prof. Ciccotti) is a well-known expert. This will allow the proposer to complement his competences by learning about modern concepts and simulation methods in the statistical mechanics theory of reactive events.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Services Platforms and Applications for Transparent Information management in an in-hOme Network', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

The characteristics of PCs, huge storage capacity, tremendous processing power, and high flexibility are becoming available for consumer devices like set-top boxes, TVs, and VCRs. Interconnection of these devices and wireless communication with various portable devices will create a complex home system with the capacity to store many types of data and offer new ways of interacting with it. To offer the user high flexibility and ease of use, new solutions are required. Advanced retrieval methods are needed to support accessing data stored anywhere in the home system from any device. Meta-data obtained through analysis, services, and logging user behaviour is needed to support these functions. Transfer of data must be easy, and transfer and adaptation of accompanying meta-data must be transparent to the user. The combination of broadcast, storage, and Internet will open the way to new types of applications and interactions with the home system.Objectives:A large distributed storage space will be available in future home networks consisting of CE equipment, PCs and handheld devices. The objective of this project is to find innovative solutions for the movement, organisation and retrieval of information in such a heterogeneous home system.Three major technical issues are to be solved:1) New Meta-data computing methods are needed to support advanced retrieval methods. This means, we need to solve how to generate meta-data by analysing the content, how to combine meta-data from various sources and how to transform meta-data for use by different devices.2) We will realise new services providing meta-data, applications and UIs to make retrieval of information easier for non-IT-expert users.3) Standards for inter-storage communication need to be extended in the area of handheld
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Multisensory Navigation: Harnessing the Power of Multisensory Processing  Optogenetic Stimulation to Aid The Blind'.

assistant: **Concept**

In Europe 30M people are visually impaired (VI), 2.5M of which are entirely blind. Despite many efforts on the societal level, VIs are still ‘left in the dark’, when it comes to independent navigation. Neuroscience has the long-term potential to provide brain-prostheses, which circumvent damaged parts of the visual system. In the present project, we will investigate how spatial information can assist VIs during navigation by non-invasive and invasive information delivery.We will make use of multisensory integration and optogenetic stimulation to investigate these questions in an animal model of navigation in the dark. Mice use their sensory hairs (‘whiskers’) analogous to how VIs use their cane for exploring their local surroundings. During this tactile navigation VIs also utilize the sound generated by their cane to provide both spatial and material information about their surroundings, evidence for a multisensory strategy.Specifically we will first investigate the effect of multisensory information on the neural representation of tactile information during natural exploratory behaviour. For this purpose we will provide sounds rapidly (<1ms) in sync with each surface contact of the whisker. These sounds are modulated by the animal’s distance to the object or will provide contextually relevant spatial information (e.g. distant targets). We predict that even soft auditory information will boost the usefulness of tactile information (‘inverse effectiveness’) and allow faster behavioural judgments in a spatial task. Next, we will provide spatial information directly to the tactile cortex using optogenetic stimulation, emulating the functioning of future, spatial brain prostheses. We predict that animals will learn to integrate this additional information to optimize their
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'New-to-nature biosurfactants by metabolic engineering: production and application' (BIOSURFING) targeting Seventh Framework.

assistant: **Abstract**

This project aims to create new-to-nature and tailor-made biosurfactants through metabolic engineering of the unconventional yeast Candida bombicola. Biosurfactants produced by fermentation offer a worthy alternative to traditional surfactants, which are typically derived from non-renewable petrochemical resources and may cause environmental problems due to their ecotoxicity and poor biodegradability. Despite the clear advantages of biosurfactants, their overall use is hampered by the lack of structural variation. This is in sharp contrast to chemically produced surfactants where one can introduce variation by simply changing the building blocks. Structural variation is essential as (bio)surfactants find application in a very broad range of sectors. This project aims to alleviate this fundamental limitation by developing a generic biotechnological production technology for glycolipid biosurfactants. This will in turn significantly broaden the range of commercial biosurfactants, satisfying the need for structural diversity in the market. It is expected that this technology will result in a breakthrough penetration of glycolipid biosurfactants in the overall surfactant market, in this way helping to build the bio-based economy.Indeed, biosurfactants are a promising target for the biobased economy as the world surfactant production exceeds 13 Mton/year and is meanly based on petrochemical raw materials.The very efficient biosurfactant producing yeast C. bombicola will be metabolically engineered such that all structural parts of the glycolipid biosurfactant molecule can be controlled: fatty acid tail, sugar moiety, acetylation and lactonization. New technology for metabolic engineering of unconventional organisms such as the use of meganucleases will be developed and strai
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'CRYSTALLINE ROCK RETENTION PROCESSES' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

The EURATOM FP7 Collaborative Project “Crystalline Rock Retention Processes” (CP CROCK) is established with the overall objective to develop a methodology for decreasing the uncertainty in the long-term prediction of the radionuclide migration in the crystalline rock far-field. The project is launched in response to the need identified in conjunction with selection of retention data for the forthcoming crystalline host-rock HLW disposal Safety Case. The process of selecting a set of data for this purpose showed that the spread in data is broad and that this spread in data cannot presently be related to material properties or processes. Consequently, very conservative numbers need to be used in order to be defendable within the Safety Case. This does not lead to unacceptable dose predictions, but remains highly unsatisfactorily.The project makes use of the broad set of existing analytical approaches, methodologies, and general knowledge from decades of past investigations. It builds on the output and main conclusions of the 6th FP IP FUNMIG project and the Swedish site selection program. The experimental program reaches from the nano-resolution to the PA relevant real site scale, delineating physical and chemical retention processes. Existing and new analytical information provided within the project is used to set up step-wise methodologies for up-scaling of processes from the nano-scale through to the PA relevant km-scale. Modeling includes testing up-scaling process and parameters for the application to PA and in particular, the reduction of uncertainty.The 21/2 years project is implemented by a consortium with 10 Beneficiaries consisting of large European Research Institutions, Universities and SME’s and from countries with dedicated crystalline host-rock disposal pr