RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Looking to a positive future - quality of life of older people with intellectual disabilities (MERCURIUS)' (MERCURIUS).

assistant: **Concept**

Why? What problem it is solving? Objectives? How will they be achieved? What results are expected? Due to the continuous improvement in healthcare the average life expectancy of people with intellectual disabilities is steadily rising. This creates new needs in relation to training of personnel, housing facilities and the role and needs of caregivers. In order to anticipate on these needs comprehensive research has to be undertaken. To enhance the efficiency of such research all stakeholders can best define the topics? It is therefore proposed to organise a EU-wide conference in which experts participate representing research institutions, the care sector and people with disabilities. The major outcome will be developed relevant research topics. A comprehensive overview will be made of the new demands that care systems in the EU will have to face. This overview will be of use for future policy for older people with intellectual disabilities.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Unification of physical and clinical requirements for medical x-ray imaging and its relevance to European industrial and socio-economic development' (1998-2002).

assistant: **Innovation**

The proposal aims to develop the scientific underpinning of diagnostic radiology which is one of the most widely employed diagnostic techniques in health care. It would help to enable European manufacturers, who compete worldwide, to understand more fully the end users requirements. Similarly the European medical community and population at large would benefit from the use of x-ray imaging systems which would meet requirements included in the EC Medical Exposure Directive 97/43/EURATOM.The project tackles a pressing problem in the field of medical x-ray imaging, namely how to unify physical and clinical assessments of image quality so that the medical users and commercial manufacturers could more effectively define and implement future technological developments. This problem is now more relevant since new totally digital x-ray imaging systems are being developed for diagnostic radiography which at present accounts for some 70-80% of all diagnostic x- ray procedures. Unlike film, which is presently employed, these systems will not impose any inherent limitation on patient exposure since electronic amplification of signals will ensure that images can be displayed adequately for a very wide range of x-ray exposure. Based upon past experience end users will naturally request the highest quality image which can be produced by employing a higher level of exposure
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Research on Really Reliable and Secure Systems Software'.

assistant: **Innovation**

Current operating systems have poor reliability and security. Computers crash regularly whereas other electronic devices such as televisions and mobile phones never crash. Furthermore, practically every week one reads about another security hole in Windows. As computers become more essential for all aspects of society this situation is unacceptable. The goal of my proposed research is to conceive, design, implement, and test an operating system that is as reliable and secure as is humanly possible. The job will be finished when the average user has never experienced a crash in his lifetime and RESET buttons on computers have passed into history, like 5¼ -inch floppy disks.       The basic concept I want to use to achieve a reliable, secure operating system is the POLA The Principle of Least Authority. The operating system will be moved out the kernel (where it has unrestricted access to all of memory, critical machine instructions the I/O devices) into a set of multiple, tightly constrained user processes. Each process (e.g., a file server) will be given exactly the authority it needs to do its job and no more. This mechanism ensures that problems in one process cannot spill over into other ones. While this goal has floated around for years, no one really knows how to do it, so research is needed. Furthermore, I also want to make the system fault tolerant and self healing so it can continue to run even in the presence of hardware and software errors. Recovery should be done automatically without affecting running programs.      Designing and building a new operating system that runs counter to 50 years of experience is extremely ground-breaking and ambitious. But the current road we are on with millions of lines of code in the kernel and growing all the time cannot be s
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Trans-Spin NanoArchitectures: from birth to functionalities in magnetic field' in the context of a Horizon 2020 call.

assistant: **Objectives**

Control over electrons in molecules and periodic solids can be reached via manipulation of their internal quantum degrees of freedom. The most prominent and exploited case is the electronic spin accommodated in standalone spin units composed of 1 – 10^5 of spins. A challenging alternative to the spin is the binary quantum degree of freedom, termed pseudospin existing e.g. in two-dimensional semiconductors. The aim of the proposed research is to build prototypes of trans-spin nano-architectures composed of at least two divergent spin entities, the TSuNAMIes. The spin entities of interest correspond to single atomic spin embedded in spin crossover complexes (SCO), molecular spin of molecular magnets (SMM), superspins of single-domain magnetic nanoparticles (SuperS) and pseudospins in two-dimensional transition metal dichalcogenides (PseudoS). Ultimate goal of the project is to identify a profit from trans-spin cooperation between the different spin entities coexisting in a single TSuNAMI. Influence of external static and alternating magnetic fields on the elementary spin state, unit cell magnetic structure, long-range magnetic order, mesoscopic spin order, spin relaxations and pseudospin state mirrored in essential fingerprints of the spin units and their ensembles will be explored using macroscopic and microscopic in situ and ex situ probes, including Raman and Mössbauer spectroscopies in magnetic field.  Within the proposed high-risk/high-gain trans-spin strategy, we thus expect: 1. Enhancement of magnetic anisotropy in SMM-SuperS with enormous impact on cancer therapy using magnetic fluid hyperthermia, 2. Control over SCO via coupling to giant classical spin giving rise to miniature ‘on-particle’ sensors, 3. Mutual visualization of electronic states in SCO-PseudoS push
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Ser-Col; from finger to laboratory; personalized and automated serum collection for laboratory diagnostics' under Horizon 2020.

assistant: **Concept**

95% of blood collected via venipuncture is not used for diagnostic measurements, and needs to be disposed as biohazardous waste by incineration, which is incredibly wasteful and taxing on our environment. In Europe, there is an urgent need for innovative approaches that engage vulnerable groups and increase access to infectious disease testing by breaking-down social and logistic barriers to healthcare. The decentralization of healthcare have created a need for a simple, safe, standardized and painless collection of serum specimens. The Ser-Col® is a novel serum separation device that simplifies and combines both blood collection and serum separation.  With a few drops of blood from a finger stick, serum can be collected which is stable for several months prior to analysis of clinically relevant serum parameters, and thereby reducing biohazardous waste production by 50%. Ser-Col simplifies and reduces the cost of serum sampling by replacing the blood tube, trained personnel, cold storage, and centrifuge with a reliable and easy to use device that links target population to centralized diagnostics laboratories, ultimately leading to the long-term reduction of the burden of infectious diseases. The SCAUT consortium will scale up manufacturing to deliver a market ready version of the Ser-Col and validate its clinical performance against existing standards. To ensure market uptake the consortium will develop an automated serum processing platform for optimal compatibility with exciting laboratory diagnostic equipment and facilitate adoption of Ser-Col by healthcare professionals. This will accelerate commercialization, attract investors and to establish industry partnerships required to realize the full potential of the technology. The SCAUT project seeks to obtain €3 milli
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Lead free soldering also for sme's' (1998-2002).

assistant: **Concept**

Like Multinationals, SME's in the electronic (assembling) industry are forced to release lead free soldering processes due to international competition (Asia/Japan), demands from customers and EU-regulation: directive on Waste in Electronics and Electrical Equipment and on Reduction Of use of certain Hazardous Substances. SME companies, however, are not able to realise free soldering for their specific SME-production processes (batch and manual soldering for small series). The objective of the project is to realise lead free soldering also for SME's by: developing cost efficient methods, tolls and equipment for batch and manual soldering processes for small series production typical for SME's to:- Realize and facilitate the transition to lead free processes (on a European scale a decrease of yearly lead-consumption by SME's from 75 to 80 ton to zero is foreseen);- Assure and improve quality (yield) and quantity (output) production (a production costs reduction of 5%; on European scale this will result in a production cost reduction and/or increase of turnover equivalent to 40 mil  per year;- Assure and improve reliability of assembled products (reliability target: 99,9%).
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Pre-doctoral research and early stage training in plant sciences and microbiology' demonstrating excellence, impact and implementation quality for a Sixth Framework call.

assistant: **Abstract**

The programme offers 492 months of multidisciplinary research training in plant science and microbiology, structured around seven research themes: biological chemistry; computational biology, crop genetics; plant cell and developmental biology; disease and stress biology; metabolic biology; and molecular microbiology. The Contract will run from April 2006 to March 2010, with recruitment of Fellows from October 2006.There will be three sub-programmes offering different formats for research training:(1) A Three-Year PhD Programme (252 months) with seven Fellows (one for each of the scientific themes) each undertaking a 3-year PhD studentship as part of an interactive training programme;(2) A Four-Year Rotation PhD Programme (144 months) with six Fellows (each sponsored for 2 years from EU and for 2 years from a second sponsor) undertaking three short research rotations in the first year, followed by a 3-year research project leading to a PhD degree;(3) A Short-term Fellowship Programme (96 months) with 8-16 Fellows each undertaking research projects of 6-12 months' duration leading in some cases to a 1-year Masters (MSc) degree.The interdisciplinary research objectives are:- to discover basic biological processes in plants and microorganisms;- to develop and apply the platform technologies that underpin modern molecular biology, and- to create plants and bacteria of enhanced value.Each Fellow will be guided by an individual research supervisor, and advised by a supervisory committee that meets regularly to discuss research progress, plans and further training and career objectives. Fellows will benefit from an outstanding environment for early stage research training in a single large multidisciplinary host institution with an outstanding record of publication in top-rank
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Approaching an answer to the complex question ‘how do childhood anxiety disorders develop?’ by merging attachment and social learning theory and their methodologies', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

“Everybody is afraid of something, but I outgrew my childhood fears. Just give your child some time, and I am sure she will grow out of it too.” Words like these are frequently reported by parents who bring their child to treatment of anxiety disorders. Although the statement is partially true - anxiety is a normal part of life, and some children outgrow their fears - it also shows that knowledge about anxiety and its detrimental effect on the child, family and society is lacking. Anxiety disorders are among the most common psychiatric disturbances in childhood with clinical levels of anxiety between 6-10%. Left untreated it increases the risk of academic and social failure as well as psychopathology in adulthood. The societal costs are significant. The development and maintenance of anxiety disorders involves a complex interplay among risk and protective factors in the child, parents and society. Different research traditions have focused on different factors in this complex equation. Attachment theory has provided insights into the impact of parent-child interactions on the child’s psychic development in longitudinal normal samples. Social learning theory and the associated treatment, cognitive behaviour therapy, has focused on e.g. emotional and cognitive factors in clinically anxious children and their parents. Unfortunately knowledge regarding the connections among child, parent, family and societal factors is sparse and research has yet to explain who will develop anxiety and why. The purpose of the present proposal is to take the field a step further, by merging theoretical perspectives and applying gold-standard methodologies, developed on both sides of the Atlantic, from both perspectives. The proposed work addresses the interrelation between anxiety disorders,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Microbiota mediating Vagal communication in Obesity'.

assistant: **Innovation**

Obesity and its comorbidities currently represent major societal and health challenges worldwide. Its prevalence has reached epidemic proportions and trends continue to rise. This situation highlights the need for more effective preventive measures. The realization that the gut microbiota could play a central role in human energy metabolism has constituted an unprecedented shift in the way we envision obesity management. Nonetheless, we still lack understanding of which the key gut microbiota players are and how they communicate with the host, thus hindering further advances in the design and clinical applicability of microbiome-based strategies to combat obesity. Preclinical studies indicate that gut microbiota impact on energy homeostasis by modulating gastrointestinal innervation function, including vagal afferent fibres, which are involved in regulating the gut-brain-periphery axis. Scientific evidence suggests that vagal afferent function may be directly affected by gut microbiota or indirectly by the enteroendocrine system, also modulated by gut microbiota. The aim of the miVaO (microbiota mediating Vagal communication in Obesity) proposal is to a gain greater understanding of how gut microbiota influences the gut-brain axis by modulating gut vagal innervations and the subsequent impact on energy homeostasis and, in particular, on white adipose tissue. To achieve this general aim, we propose using the intestinal human bacteria biobank created in the context of the EUproject MyNewGut  by the host institution to: 1) identify bacterial strains with potential neuroactive properties; 2) discern between direct and indirect-enteroendocrine-mediated bacterial effects on vagal afferents and 3) identify the best candidate strain able to prevent or attenuate obesity by modul
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Multiscale Materials Modelling on High Performance Computer Architectures' (2007-2013) under Seventh Framework.

assistant: **Objectives**

With the accelerating materials development cycles, the development of simulation approaches for predictive, de-novo characterization and optimization of materials and device properties emerges as a grand challenge to European R&D. A unified multi-disciplinary approach towards the deployment of models, tools, algorithms and simulation and visualization techniques is required to transform isolated solutions for specific problems into comprehensive, industry-ready platforms, which are capable of predicting the properties of complex materials on the basis of their constitutive elements.  While many techniques exist to address the specific questions, a lack of integration of the existing methods into readily available multi-scale modelling platforms has to date limited the impact of materials-modelling techniques in materials design. In this project we will develop an integrated e-infrastructure for multi-scale materials modelling (MMM@HPC), where expert groups unite with computational resource providers to deliver an integrated infrastructure for multi-scale materials modelling. MMM@HPC will be an open platform to integrate of existing software modules into customizable, high performance protocols and workflows. We will provide the European research community with a leading edge software infrastructure to exploit the highest quality software and computational  resources; enabling Europe to address the emerging grand challenges in materials science and engineering. MMM@HPC will strengthen Europe's international role as software provider and nucleate  a unified community of computational scientists to address emerging computing needs of the research community with a very efficient, evolving research tool.  The project will demonstrate a direct impact towards solving visible
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Genetic conflict and the evolution of alternative reproductive systems'.

assistant: **Innovation**

During sexual reproduction, two unrelated individuals cooperate to achieve a common goal: pass on their genes to the next generation. This cooperation is however not without conflict, parents can fight over who raises the kids, females can cheat and mate with other males. But at least in most animals genes of the mother and father are equally represented in the offspring. This is not always the case. In my research I study a group of insects who’s reproduction is incredibly variable and where evolutionary innovations appear to have reduced the importance of males in reproduction. For example in the citrus mealybug, males are still needed to fertilize females, but the female can eliminate his genes from her son. In the cottony cushion scale, evolution appears to have driven the male to become a parasite living in the body of the female, producing sperm and fertilizing her from within. My research aims to study how conflict between the sexes, both directly and indirectly (conflict between mothers and fathers genes within an offspring) can have lead to the evolution of these strange reproductive behaviours and might help to explain the large diversity of reproductive systems among animals.