RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'DEVELOPMENT AND EVOLUTION OF TISSUE COMPLEXITY IN PLANTS: THE BRASSICACEAE STEM CELL DEVELOPMENT', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

The formation of the plant body requires the assembly of different tissue systems in an organized pattern to make organs. The aim of this project is to understand how the formation of complex tissue systems is genetically regulated and how has been acquired during plant evolution. A preliminary analysis of the variation in ground tissue anatomies in different species across the Brassicaceae has showed a remarkable diversity of ground tissue phenotypes in this family. We intend to use this diversity to investigate the developmental and evolutionary mechanisms underlying tissue complexity in plants. We will compare the ground tissue organization of A. thaliana with two other Brassicaceae species, Cardamine hirsuta and Thellungiella halophila. The double layered cortex of these species gives us the opportunity of studying the developmental basis of the formation of a multi-layered cortex. T. halophila is one of the few examples of plants that form a double endodermis. This project will try to uncover the molecular mechanism underlying this almost unique ground tissue organization. Our hypothesis is that similar key regulatory genes will regulate the formation of complex and simple ground tissue systems in this family and that changes in their patterns of expression are responsible for the differences that arise between species. To check this hypothesis we will analyse the expression, function and molecular differences of the orthologous genes of three ground tissue A. thaliana transcription factors, SCHIZORIZA, SHORTROOT and SCARECROW. To identify new genetic components of this process we will generate mutagenized populations and search for mutants with defective ground tissue phenotypes and will compare transcriptional profiles between species. Finally, the analysis of th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Assessment and development of new concepts for management structures of shipowners and ship operatores' under Fourth Framework.

assistant: **Concept**

The MASSOP project aims to create workable new organisational forms for the shipping industry. It is based upon the idea that the traditional rigid command and control" hierarchy, both at sea and ashore, may not be the best solution for today's shipping world.MASSOP aims to evaluate the global state-of-the-art of present management structures in the shipping industry. The rapidly changing political, economic, social and technical aspects will be studied, and MASSOP aims to provide cost-effective management concepts, in conjunction with studies of other industries and case studies, to improve the performance of shipowners and operators both at sea and ashore.MASSOP also aims to realistically analyse the likely obstacles to growth for the European maritime industry and highlight the strengths and weaknesses. This will be seen through the framework of deregulation which is occurring, but balanced with the increased quality standards which are being introduced.The project will also provide the syllabus for a course in the change of management in the shipping industry. This course is envisaged to be specifically for the senior management of shipping companies. %"
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'In-toto imaging of C. elegans larval development using adaptive optics light-sheet microscopy' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Our project aims to combine concepts and methodologies from biology, physics and engineering to address a fundamental question in neuroscience: how is the nervous system rewired during development transitions. The nematode C. elegans is one of the most important model organisms in neuroscience due to its relatively simple stereotypical anatomy, well-studied genetics and behavior, translucent body and nervous system, ideally suited for in-toto (in its entirety) imaging. Yet most of the knowledge available refers to adult animals, and little is known about neuronal plasticity and mechanisms of behavioral changes during development. One of the technical reasons for this gap is the lack of high-resolution fast-scanning optical microscopes compatible with microfluidic devices that are routinely used in nematode larva studies. To address this limitation, we propose to build a light-sheet microscope for imaging C. elegans larvae in conventional microfluidic chips with high spatio-temporal resolution, and minimize the optical aberrations caused by chamber material using adaptive optics. The microscope will allow parallel imaging of larvae while exiting dauer diapause (an alternative larval stage geared for survival). We will use the imaging data together with available (yet unpublished) electron microscopy reconstructions of C. elegans dauer larva to study nervous system rewiring during this critical period of animal development, and which neurons are active during developmental changes. This information will pave the way for optical manipulations of candidate neurons by laser ablations and optogenetic activation, to probe their causal roles in developmental transformations.Due to its versatile design, our microscopy technique may be further applied in other studies where high-
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Morphing tubular structures for adaptive biomedical devices' (Stripe-o-Morph) targeting Horizon Europe.

assistant: **Abstract**

Morphing tubular structures are extensively used in interventional medical devices (e.g., stents). Current solutions lack adaptability to complex geometries and to patient-specific needs. Stripe-oMorph proposes the use of devices with superior morphing capabilities, bio-inspired by motile microorganisms, previously investigated in the ERC AdG MicroMotility, and based on the concept of morphingby-sliding of parallel strips.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Innovative production of nanosized powders' (1998-2002) under Fifth Framework.

assistant: **Objectives**

The objective of this project is to develop and construct a new type of pulse combustion system for the production of nanosized powders. The pulse combustion technology would enable a faster production of high quality powders for use, in for instance, the ceramic industry at lower costs, at lower energy consumption and with a significant reduction of the environmental contamination. A reduced production costs would enable more markets to profit from the use of these nanosized powders, which, moreover, have a higher quality. At this moment the production costs of these nanosized powders in general is extremely high, which limits the application fields. The objectives would be met by the innovative production of nanosized powders via a pulse combustion system.Nanosized powders have emerged as an important product for high performance components whose worldwide markets are expected to reach Euro 5 billion by the year 2001. With the new high quality nanopowders the life span of its end-products is expected to increase with 20 %.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Hydrogen from renewable energy for commercial building heating – a full supply chain demonstration' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

The overall aim of the H2Heat project is to demonstrate the full value chain for green hydrogen (H2) heating for commercial building heating. 40% of total energy consumed and 36% of greenhouse gas emissions in EU correspond to buildings, with 79% of that energy used for heating of water and air conditioning. H2HEAT, in exciting alliance with the Canary Health Service (SCS), wish to create a full demonstration of Green H2 for heating (and later energy). This will serve as the replicable model to be rolled out across the SCS hospitals enabling the SCS fulfil its ambitious ‘Health Zer0 net Emissions Strategy’ delivering deep decarbonization.H2HEAT will use offshore wind renewable energy (RE) to produce H2, from  Esteyco 6MW EU funded WHEEL project. The centralised onshore H2 facility, will produce H2 initially with a 1MW electrolyser, to be used to substitute conventional fuel by the large end-user hospital CHUIMI with substantial heating requirements (>0.5MW), using a novel combination of an advanced combustion technology burner specifically designed for H2 operation H2-CHP, and a heat pump. The H2-CHP will produce heat and energy and the energy will power the heat pump for substantial heat provision to the hospital with no waste. Full end-to-end infrastructure for H2 transport and use will be planned, installed and commissioned.  Comprehensive and complementary mixture of expertise and know-how provided by the consortium partners will ensure an efficient realization of the technical objectives of the project, reduce total cost of ownership (TCO) of H2 fuel for consumers, and develop replicable business models for wide-scale commercial usage of H2 as a direct heating alternative across Gran Canaria. H2Heat will contribute to enabling Gran Canaria become part of the H2 val
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Prevention of Hospital Infections by Intervention and Training' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

The aim of PROHIBIT is to understand existing guidelines and practices to prevent healthcare associated infections (HAI) in European hospitals, identify factors that enable and prevent compliance with best practices, and test the effectiveness of interventions of known efficacy. The project will employ a mixed-methods approach combining the strengths of qualitative research, survey methods, observational and experimental designs. First, we will systematically review current guidelines on prevention of the most common HAIs within the EU, as well as schemes for surveillance and public reporting. Next, we will conduct a large-scale survey of what is actually being done in European hospitals, determining factors, and how these relate to bloodstream infection rates. The project will then focus on catheter-related bloodstream infection (CRBSI), a highly transmissible and reliably measured HAI, in a selected sample of European hospitals. In-depth interviews of healthcare staff and direct observation will be used to measure compliance with key prevention practices. A randomized effectiveness trial using a stepped wedge design will be conducted in intensive care units to determine the uptake and impact of 2 interventions (WHO hand hygiene protocol and so-called catheter bundle) on CRBSI as well as clinical and utilization outcomes. The information will be synthesized to develop recommendations for the EU, policy makers, managers and medical professionals to prevent HAI. Dissemination will include instructional workshops and on-line training materials.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'siRNA-based therapy for cerebral tauopathies' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Neurodegenerative disorders are an increasing healthcare problem. Many of these diseases are characterized by aggregation of proteins, which leads to neuronal dysregulation and cell death. Neurofibrillary tangles, pathological aggregates of tau protein, are the characteristic neuropathological stigmata defining a group of disorders termed Tauopathies. In Frontotemporal Dementias with Parkinsonism linked to Chromosome 17 (FTDP-17), mutations in the tau gene have been identified as cause of the disease. Mice expressing FTDP-17-mutant tau protein develop age-related accumulations of neurofibrillary tangles, behavioural impairments and neuronal cell loss, similar to patients with FTDP-17. When the expression of such mutant tau protein was suppressed by means of a tetracycline-controlled expression system in mice with advanced pathology, cognitive deficits were reversed and neuronal loss was prevented. We therefore propose to study if the small inference RNA (siRNA) technique can be instrumentalized in transgenic mice overexpressing human wild-type or mutant tau (R406/P301S) to suppress tau-gene expression, neuronal cell loss and behavioural deficits. To achieve widespread distribution of siRNA in the brain, a polyethyleneimine delivery system with intracerebroventricular administration will be used, which technique has a good chance to qualify for clinical application. We believe that this project will significantly advance the research in tau-related pathologies.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Intervention Research On Health Literacy among  Ageing population' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

The IROHLA project aims at innovating the conceptual understanding of health literacy interventions in Europe. Health literacy is one of the social determinants of health and reflects how well persons can understand, digest and critically reflect on information with regard to health and illness. People with sufficient health literacy skills are able to act proactively on health issues, take their own decisions and manage health and illnesses well. Right now in EU countries 10% – 30% of the population has insufficient health literacy skills, which is associated with higher morbidity and mortality, while utilisation of health services is higher and treatment outcomes are poorer than average. Health literacy is a major issue amongst the ageing population in Europe. Tackling health literacy problems in the ageing population leads to social innovation and leads to reduction of costs of healthcare.The IROHLA project will investigate health literacy interventions among the ageing population and will draw lessons from other sectors, e.g. the social sector and the commercial sector.  By involving scientist from medical, paramedical field, social and behavioural sciences, communication sciences and other related fields, the project will be truly multidisciplinary. The project will involve stakeholders from the ageing population and from levels of government.The project will develop a comprehensive approach for health literacy among the ageing population, based on synergetic effects of empowerment and health literacy communication, which countries can apply in prevention, curative services and care services. The project will concentrate on modern media and e-health applications. The final product will be a guideline for policy and practice with (max) 20 high potential intervention
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'The relationship between social inequalities, child mental health and exposure to urban environmental stressors: an epidemiological analysis' to be submitted under Horizon 2020.

assistant: **Abstract**

Mental health disorders are one of the primary sources of ill health for young people, affecting up to 20% of children and adolescents worldwide. Moreover, stark social inequalities in children’s mental health exist, with those from more disadvantaged backgrounds being up to three times more likely to experience mental health problems than those more privileged.Our understanding of the mechanisms through which childhood socio-economic circumstances (SEC) affect children’s mental health is incomplete. With three quarters of EU citizens now living in cities, attention is turning to the effects of environmental stressors such as ambient air pollution, traffic noise, and natural space on children’s development. In many cities, children from lower socio-economic backgrounds are disproportionately exposed to more harmful aspects of the urban environment. However, we do not know to what extent greater exposure or vulnerability to these stressors contributes to social inequalities in child mental health. URBINEX will undertake epidemiological analysis of data from over 200,000 children across 16 EU cities using the recently established EU Child Cohort Network. Cutting-edge methods in causal inference and life course epidemiology will be applied to decompose the relationship between SEC, exposure to environmental stressors and children’s mental health. The key objectives are to (i) use multi-level models to describe inequalities in mental health trajectories across childhood, (ii) use counterfactual mediation to test whether variation in exposure to urban environmental stressors mediates the relationship between SEC and mental health, and (iii) explore whether SEC and environmental stressors interact to confer additional vulnerability to mental health problems.URBINEX has the po
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Developmental and evolutionary origins of the language of thought'.

assistant: **Innovation**

How do human infants and non-human animals think? Fodor famously framed the idea that human minds operate in a language-like format, a language of thought (LoT), where mental representations compose in the manner of formal language symbols, allowing us to build arbitrarily complex mental structures out of a small set of initial primitive operations. Through all areas of cognitive science, there has been rich evidence supporting the idea that a LoT could explain many facets of human cognition. Do infants and animals also have a LoT? While the existence of a LoT in the absence of language has been questioned for centuries by philosophers, psychologists and linguists alike, little direct behavioral evidence has been offered for it and these investigations have mainly been confined to close relatives of humans (i.e., great apes). The overarching goal of this project is to adopt a broad comparative approach to study the developmental and evolutionary origins of the LoT. Our approach is at the intersection of linguistics and psychology: we identify the primitive operations of thought from formal semantic principles and operations realized in language, and empirically test them in human adults and infants, baboons (Papio papio), and honeybees (Apis mellifera). We study the computational architecture of the LoT of infants and animals, starting from their ability to perform simple computations using only a few symbols to the more complex abilities to use functional operators, such as logical connectives, quantifiers and modals and to apply pragmatic operations. The outcome of this project will be an unprecedented cartography of possible LoT primitives, and of where they are found in human ontogeny and animal phylogeny.


**Keywords:** language of thought,  semantic universals,