RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Translational Regulation of Gene Expression by the Nascent Polypeptide Chain' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

Following initiation of protein synthesis, the nascent polypeptide must journey through the exit tunnel of the ribosome. Although this has typically been deemed a passive process, it is established that certain peptide sequences interact with rRNA components and ribosomal proteins lining the walls of the tunnel to bring protein synthesis to a complete halt. In many cases, translational arrest is dependent upon the presence of a small cofactor – such as an amino acid or an antibiotic – acting in concert with the specific peptide being synthesized.In order to gain a deeper insight into the process of nascent chain-mediated translational arrest, I propose to focus on two complementary objectives:First, I will obtain high-resolution structures of ribosome nascent chain (RNC) complexes by X-ray crystallography in order to understand the mechanistic aspects of this process. Current strategies for preparing RNC complexes rely on cell-free expression systems and produce samples of varying quality and unknown stoichiometry. Here, I propose to prepare peptidyl-tRNAs by attaching chemically synthesized peptides onto tRNAs expressed in vivo, using small RNA enzymes known as a flexizymes. Peptidyl-tRNAs obtained in this manner will be added to the ribosome in trans to obtain RNC complexes, thereby sidestepping some of the problems that result from ribosomal peptide synthesis in cis.Second I will explore the functional diversity of nascent chain-mediated arrest by developing an in vitro selection/evolution method that will enable the identification of cis-regulatory nascent peptides capable of inhibiting the ribosome with the help of small molecules. By integrating the structure and sequence data obtained from our studies, we will develop a predictive algorithm for identifying regula
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'SMART MOBILITY IN SMART CITY', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Urban transport is responsible for about a quarter of CO2 emissions from transport. The gradual phasing out of 'conventionally-fuelled' vehicles from the urban environment is a major contribution to significant reduction of oil dependence, greenhouse gas emissions and local air and noise pollution. Fully Electric Vehicles (FEV), for public and private transport, can contribute significantly to the lowering of the current pollution levels. However, the FEV use is currently facing several weaknesses which are delaying its wider deployment, mainly related to overall limited efficiency and limited driving range.With this regard, MOBINCITY aims at the optimization of FEV autonomy range and the increase in energy efficiency thanks to the development of a complete ICT-based integrated system able to interact between driver, vehicle and transport and energy infrastructures, taking advantage of the information provided from these sources in order to optimise both energy charging and discharging processes (trip planning and routing).Main specific objectives are: To develop a system to be installed within the vehicle able to receive information from the surrounding environment, which can have influence in the vehicle performance (traffic information, weather and road conditions and energy grid). To optimise the trip planning and routing of FEV using information from these external sources including alternatives from other transport modes adapted to user's needs. To define efficient and optimum charging strategies (including routing) adapted to user and FEV needs and grid conditions. To implement additional energy saving methods (as driving modes and In-Car Energy Management Services) within the FEV interaction with the driver.In order to reach its objectives, MOBINCITY joins toget
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Real Organ Generation' (ROG) under Horizon 2020.

assistant: **Objectives**

MTM S.r.l has developed a game-changing platform comprising 1) an algorithm able capture 2D images and convert them into 3D geometries ( we have already validated our solution on Cardiac Imaging), in order to generate hyper realistic ( more than 10X resolution respect of the best 3D medical imaging today present in the market) models/mockups, ready to be used in VR and 3D printing allowing an unprecedent medical training approach, as well as a simulation of real patients’ condition on which perform pre-operative simulation in healthcare environment; 2) a sophisticated software able to manage multiple actions: such as loading 2D image parts produced by medical scanning devices (organs and tissues), generating 3D models from 2D images elaborated by our algorithm, enable the user (thanks to our intuitive GUI – Graphical User Interface) to visualise the 3D model, (choosing from different views, differentiate surfaces, anatomical sections, layers, regions of interests), recognising anomalies, tagging the mutations and the morphology aberrations, supporting and collecting extensive libraries of 2D images and 3D models, enabling an unprecedent new way to train students and surgeons during critical preparation to surgery.ROG’s business model. We already mapped our value chain and plan each phase of our path to exploitation. Our revenue model will be a combination based on: ROG software platform licensing and sales from personalized processing of 3D image services (The specialized paid services will instead involve the personalized processing of 3D images, the tagging performed by semi-automated expert systems and the possibility of having training sessions on the platform).  As a result of the maturation strategy and the higher potential value of our system, we will see growth
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Strengthening Translational Research for Improved Metabolic Health' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

Curbing obesity-related diseases is one of key priorities of the Horizon Europe 2023-2024 work programme. Although metabolic dysfunction-associated steatotic liver disease (MASLD) is the most common chronic liver disease and prominent manifestation of metabolic syndrome, its real socioeconomic burden is likely underestimated. Serbia is affected both socially and economically by the increasing incidence of MASLD, with a prevalence of 45%. Therefore, the establishment of a center for metabolic disease research in this region is an important priority. The STRIMHealth project aims to develop a joint research strategy of Institute for Biological Research Sinia Stankovi (IBISS) with three leading European institutions, in order to step-up and promote scientific excellence and innovation capacity of IBISS, and to establish the Metabolic Disease Research Unit as European Knowledge Hub. The project partners have multidisciplinary skills and complementary knowledge that will significantly enhance the research and management capacity of IBISS and increase its visibility, attractiveness and networking.The objectives of the STRIMHealth project are: 1) to enhance IBISS scientific excellence by creating an impactful research framework with leading EU research institutions; 2) to strengthen IBISS research capacity for forefront translational research; 3) to sustain IBISS' growth by improving its research management and administrative capabilities; 4) to strengthen and expand IBISS' networking with both academia and industry. These aims will be achieved through a series of research partnerships, workshops, trainings, knowledge exchanges and staff visits, and transfer of experience between partners. STRIMHealth project will increase IBISS research capacity in the field of metabolic disea
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Video Livestreaming Has Never Been Easier And Can Help Us Stay Connected During COVID-19' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Livestreaming offers many opportunities for marketing and information but its uptake is limited due to time-consuming and expensive systems. Video streaming is the fastest growing way that audiences are consuming content. Challenges associated with video live streaming include bandwidth issues. The global video streaming software market is expected to rocket to over €9 billion by 2023.  Contentflow provides a complete livestreaming platform ranging from a single hub for Contentflow is already in the process of assisting in the critical situation with COVID-19. For instance, just in March 14th 2020,  Contentflow has helped the Bavarian City Championships to be held virtually instead. Contentflow is the only technology that offers flexibility for different formats, a cloud-based engine that allows exporting and live-clipping of live streams, automated subtitles in all major languages, white label solutions, parallel live-streaming, player functionality, live stream editing, streaming in Full-HD and restreaming to all major social platforms (e.g. Facebook, Twitter, YouTube) and advanced analytics. Contentflow’s advanced analytics allows its users to get access to the vital information on their audience so that they can provide optimum content. Contentflow is helping companies to be able to continue sharing information via live streaming and putting events online during the Corona Virus outbreak.   We have received a €2 million seed round investment from Speedinvest, VC Fonds Technologie Berlin, Betaworks, and Japanese Akatsuki Entertainment Technology Fund as well as other angel investors. Our clients will help us make revenues of €694,000 in 2020.  Contentflow will help democratize information in Europe by providing a reliable video streaming service that can reach anyone
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fifth Framework proposal on 'Adaptive Hypermedia'.

assistant: **Innovation**

This conference is intended as an inter-disciplinary exploration into adaptive hypertext and other kinds of flexible hypermedia systems (including but not limiting to Web-based systems). It aimed to draw together a number of research groups taking different approaches to adaptive and flexible hypertext systems, in order to promote the cross-fertilization of the ideas and highlight the prospects for future collaboration. The proposed conference builds upon and extends the scope of previous successful workshops held in conjunction with major international conferences. Time is coming now to bring together researchers on various aspects of adaptive system research in an event especially devoted to this topic. The conference will compass 3 main tracks, each on focussing on a particular topic in the field, and a parallel demo session.Moreover, a special session will be devoted to short papers presented by young researchers where they could benefit from interaction, comments and discussion about their papers in a workshop-like environment with the leading scientists. Another special session will be organized as a panel with the keynote speakers of the conference and some leading persons from industry. The aim of this session is to let researchers understand the actual industry needs as well as to let CEOs understand the great impact that these technologies may have in their business.ftp://ftp.cordis.lu/pub/improving/docs/HPCF-1999-00204-1.pdf
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'The use of Digital Embedded Systems In Robotics Engineering' (DESIRE).

assistant: **Concept**

The aim of this proposal is to assist the reintegration of the applicant into her new career environment, by implementing a research project which will span over a period of 12 months. The proposal aims to further exploit previous research carried out during a 3-year Marie Curie Industry Host Fellowship in Italy. One of the main focal points of the research project is to promote the use of embedded vision systems and neural architectures to develop intelligent control systems that are typical of robotic applications. This project, however, will extend these principles to a broader prospect, by promoting the use of embedded circuits to build miniaturised robotic systems characterised by their power efficiency, small size, low cost and high performance, thus increasing their suitability for autonomous use in applications where battery life, mobility and overall performance are crucial requirements. The project therefore investigates design paradigms that may be applied to constructing cost-effective robotic machines that can be used in environmentally hazardous conditions to perform tasks such as unmanned industrial applications, the search for survivors in emergency services, landmine detection, and aerospace applications. The research project will be carried out in three phases. During the first phase laboratory facilities will be established. During the second phase, the researcher and her students will familiarise themselves with the engineering of robots through laboratory experimentation. This will be combined with academic teaching of robotics courses to undergraduate students. Finally, during the third phase, five engineering students will be recruited to develop prototypes of autonomous robotic systems that employ embedded systems techniques for realising control
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'The role of apc tumor suppressor gene in development and tumorigenesis of the central nervous system - the conditional gene inactivation approach' demonstrating excellence, impact and implementation quality for a Fourth Framework call.

assistant: **Abstract**

Research objectives and content Germline mutations of the Apc tumor suppressor gene cause FAP (Familial Adenomatous Polyposis), a rare hereditary colorectal cancer syndrome and somatic mutations of Apc occur in the great majority of sporadic colorectal tumors. Recent studies have demonstrated that the Apc protein is expressed in most tissues during the mouse development and in adult animals. As an example, Apc is highly expressed in post mitotic neurons in specific brain areas, such as the cerebellum during development. An interesting correspondence to these findings is that a considerable percentage of patients with FAP develop also medulloblastomas, a highly malignant embryonic tumor of the cerebellum. The role played by Apc in this different context is still unclear. To date, the available mouse models, such as the Apc Min mouse and the conventional knock out are not suitable to address these questions. In both cases the heterozygous die in the first months of life as a consequence of the intestinal tumors and the homozygous mutants are embryonic lethal. In order to study the effects of selective inactivation of Apc in vivo we are generating conditional Apc mouse mutants using the Cre/LoxP site specific DNA recombination system. LoxP sites are being introduced in intron 1 and 2 kb downstream to the polyA tail of the Apc gene via homologous recombination in ES cells. ES cell clones with the targeted Apc lox alleles will be used to generate conditional mouse mutants. These mice will be crossed with transgenic mouse strains expressing the Cre recombinase in a tissue specific fashion. Training content (objective, benefit and expected impact) The potential of transgenic technologies for the advancement of medical science is playing a crucial role in narrowing the gap betw
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Living Lab research concept in Rural Areas' to be submitted under Horizon 2020.

assistant: **Abstract**

LIVERUR aims at expanding an extremely innovative business model called Living Labs among the rural regions. Living labs are user-centred, open-innovation ecosystems often operating in a territorial context, integrating concurrent research and innovation process within a public-private partnership. The basis for the strategic development of a rural Living Lab is in establishing a sustainable stakeholder partnership; users, policy-makers, companies, researchers enter into agreements on the basis of which they may engage in longer term collaboration. However, a successful Living lab business design can be expected to be highly affected by the specific context of the Living Lab rural environment and by its specific objectives and ambitions. LIVERUR project identifies Living Labs as innovative business models that are currently developing in rural areas, and it will undertake socio-economic analysis to identify, describe and benchmark differences between the new Living Lab approach and more entrepreneurial traditional approaches (mass production, development of prices, optimising the cost structures with the enterprises, rationalisation). LIVERUR project pays particular attention to Living Labs, since they foster a more sustainable mobilisation of resources, improved cooperation between operators along the value chain and lead to new services. Living Lab utilizes the open innovation concept in a wider sense, with success/failure rate determined by empirically based research key factors. Since there is still a lack of empirically grounded studies, the short term objective of LIVERUR is to improve knowledge of business models growing in rural areas, including a through understanding of their potential. In the long term the project will increase the potential for rural economi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project '5mw wind energy converter for off-shore application' (5MW-OFFSHORE-WEC).

assistant: **Concept**

Wind energy technology has rapidly emerged into a viable, reliable and competitive energy technology of a major strategic importance. The machines of current class, that is 1.5MW to 2.5MW, will be succeeded by the Multi MW class of approximate 5MW rated power. The objective is to develop a 5MW off-shore wind generator for pilot operation.This project proposal is focused on the prototype for off-shore applications, which will differ considerably from land-based concepts. Within this project, the goal is to develop the actual hardware, and to install and operate the prototype for off-shore applications. We will also verify the generator performance in an extended pilot operation with the aim to prepare basic development which will then be used for further industrial exploration.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Equidae Hindgut Anaerobic Fungi: A key unexplored taxa of central importance to dietary fibre degradation' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

EQUIANFUN is a strategic research and training alliance I have assembled to catalyse the development of my new career path in comparative herbivore gut microbiology, and addresses a major nutritional challenge facing the equine community. The hindgut microbiota of equines enables forage utilisation; however, the limited efficiency of this process currently requires that the diets of many equines are supplemented with energy-dense concentrates in order to meet their dietary energy requirements. This practice can disturb the equine hindgut microbiota, resulting in the development of gut-mediated diseases which are a major health and welfare issue and economic cost to the equine community. Despite the fact that anaerobic fungi (AF) are the most effective of the fibre-degrading gut microbes, they have been largely overlooked in equine gut microbiology studies to date. Therefore research into this under-explored area will significantly advance the ability to increase the efficiency of forage utilisation in equines, minimising the need for concentrate supplements. Drawing on my core skills base, and utilising internationally leading expertise and facilities in gut microbiomics and animal nutrition at Wageningen University, EQUIANFUN establishes new baseline knowledge of the phylogeny, community structure, physiology and nutritional impact of equine hindgut AF. In addition to generating top quality research findings of applied impact, EQUIANFUN deepens my skills and competencies whilst broadening my research expertise and network beyond its current rumen focus. Furthermore the integrated role of the two partner organisations, Utrecht University and the Donkey Sanctuary, widens the scope of EQUIANFUN to also include the health and welfare of all domesticated equids. In summary,