RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'The strong interaction at neutron-rich extremes'.

assistant: **Objectives**

"The strong interaction at neutron-rich extremes"" (STRONGINT) will investigate the structure of matter at the neutron-rich frontier in the laboratory and in the cosmos based on chiral effective field theory (EFT) interactions. Chiral EFT opens up a systematic path to investigate many-body forces and provides unique constraints for three-neutron and four-neutron interactions. We will for the first time explore the predicted many-body forces in neutron matter and neutron-rich matter. One milestone will be set by the development of a systematic power counting for neutron-rich matter. This will enable us to carry out diagrammatic approaches, and to develop ground-breaking nonperturbative Monte-Carlo calculations. Our results will strongly constrain the nuclear equation of state at the extremes reached in core-collapse supernovae and neutron stars. Based on the developments for neutron-rich matter, we will investigate spin correlations and develop a systematic description of neutrino-matter interactions, which can set the new standard for supernova simulations. Our pioneering studies have revealed new facets of three-body forces in neutron-rich nuclei, such as their role in determining the location of the neutron dripline in oxygen and in elucidating the doubly-magic nature of calcium-48. We will investigate the impact of chiral three-nucleon forces on key regions in the r-process path and develop a chiral EFT for valence-shell interactions. This will open new horizons for understanding the shell structure of nuclei. Another milestone will be set by the first calculation of neutrino-less double-beta decay based on chiral EFT interactions and consistent electroweak currents. The proposed interdisciplinary problems are essential for a successful and quantitative understanding
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'The cosmic evolution of massive black holes' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

Massive black holes populate the centers of today's galaxies, including the Milky Way, and shone as quasars in the past; the massive black holes that we detect now in nearby bulges are the  remnants of this fiery past. The masses of black holes in local galaxies also define clear correlations with the properties of their hosts, showing that the growth of black holes is intimately linked to the one of their hosts, however, little is known about how they form and interact with their hosts in different environments, especially in at early cosmic epochs. We propose to undertake  a theoretical investigation on the formation of massive black holes and their growth inside galaxies using cosmological hydrodynamical simulations and semi analytical models. Using numerical simulations we can explore out-of-equilibrium conditions that cannot be studied analytically, while at the same time analytical models guide the simulations we run. We will use semi-analytical models to create statistical samples in an inexpensive way. The  simulations will  follow the evolution of the galaxy+black hole system from the epoch of black hole formation to today, in different types of galaxies. We will also explore the  evolution of massive black holes during galaxy mergers, which in Cold Dark Matter cosmologies are an integral part of galaxy evolution. The simulations provide information on the evolution of MBHs, that we will parameterize into our semi-analytical models to calculate properties of quasars at different redshifts and wavebands that can be directly compared to observational samples. Observational predictions, such as luminosity functions, redshift distributions, mass functions, and merger rates will be assessed by taking into consideration both currently available facilities and planned
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Greek fantastic literature: a case of censorship in a European literary canon' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Rarely have Modern Greek Studies taken into consideration any other than “serious” or mainstream works in order to establish a national “canon” and to analyze trends, worldviews or discursive strategies in Greek literature. Although disregarded by scholars and critique, there are some specific genres at the margins of official Greek literature that can reveal many things about national literature and related discursive strategies. The purpose of this project is to research one of the mentioned genres: Greek fantastic literature, which not only will demonstrate to be important by itself, but also to constitute an efficient departure for studying the processes of canon formation and literary censorship that exist within the institution of Greek literature and, at some extent, construct it. The project implies, first of all, a search for a corpus of fantastic works in Greek in the last two centuries. These works will need subsequently to be analyzed according to rigorous methodological tools (comparative literature, poststructuralist approaches, cultural studies). We will focus on some questions inherent in the existence of a Greek fantastic genre: the limits of national literature, the struggle between hegemonic and counterhegemonic discourses (in a historical, political, ontological or sexual sense), and the images of Greece and the Greeks supplied by these works. More specifically, the main goal of the project is to find out which are the strategies implied in the apparent censorship suffered by fantastic literature in the Greek canon, and their relationship with, on the one hand, the nationalist discourses that have often dominated and even determined Modern Greek culture, and, on the other, the role of literature as one of the most important institutions for the const
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'European Network for interactive and innovative knowledge exchange on animal health and nutrition between the sheep industry actors and stakeholders' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

The future of the sheep farming industry, in Europe and other associated countries, will be heavily influenced by its capacity to respond to several challenges including sustainability and profitability;  environmental (in part due to climate change); and new societal expectations. To address these challenges, animal health and nutrition management are key levers which can be used by farmers EuroSheep will focus on those 2 topics.The overall objective of the EuroSheep project is to create a self-sustainable EU/international Thematic Network on “sheep profitability through health and nutrition” designed to stimulate knowledge exchange and cross-fertilisation among a wide range of actors & stakeholders in the sheep sector in order to widely disseminate relevant and ready to use best practices and innovations, and to value the grassroots input and knowledge exchange from farmers to farmers. EuroSheep gathers experts for a transdisciplinary approach to “sheep production” (animal health, animal nutrition, grassland management, precision livestock farming, breeding and genetics, as well as sociology, economics), which will allow undertaking a multifactorial approach of practical solutions and capturing innovations on sheep farms.EuroSheep multi-actor approach engages farmers, farmers’ organizations, scientists, trainers, veterinaries and staff from advisory services involved in the sheep value chain. EuroSheep will promote a crowd-innovation approach, through networking workshops, which will stimulate wider opportunities for the collection and exchange of the existing knowledge, as well as the cooperation and dissemination of information and best practices. EuroSheep strengthens links between the EU and Turkey, with partners located in the main sheep producing countries. It c
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Targeting treatment-induced neuroendocrine prostate cancer' (TARNEPC).

assistant: **Concept**

Current treatment options for prostate cancer include use of androgen deprivation therapies to block tumor growth but often the tumors become castration-resistant. Even the second generation antiandrogens that do have significant effect on castration-resistant tumor growth in patients are not curative. Approximately 25% of prostate cancer patients with castration-resistant disease treated with antiandrogens develop a form of prostate cancer that is completely independent of androgen receptor signaling that fuels the tumor growth. Analyses of the pathology and genomics of these patient tumors has identified that the tumor cells adapt cancer stem cell and neuronal cell characteristics. Currently, there are no treatment options for this patient group. Thus, development of novel strategies including selection of drugs that could be used to reduce the tumor growth and metastases in this patient group are desperately needed. This project aims at characterizing a novel therapeutic target against aggressive, the treatment resistant neuroendocrine prostate cancer. The success of this project may significantly benefit prostate cancer patients and provide cost-effective therapy options to be utilized in health service.


**Keywords:** cancer, prostate, neuroendocrine, treatment-resistance, neuroplasticity
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Assessing and improving access to health and social care SErvices for children RENdered vulnerable by Abuse' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

SERENA will accelerate efforts to improve access to health and social care (HSC) for child victims of maltreatment (physical, sexual, psychological abuse and neglect) throughout Europe. The major ambition of SERENA is to identify and promote the means of improving the detection of child maltreatment (CM), of limiting its consequences (recurrence, severe conditions), and reducing the induced burden for victims, families, and society.This ambition will be supported by assessments of current care pathways (HSC services), the barriers and inequalities when accessing these services (before and after the recognition of CM, including children's physical and mental health conditions), as well as the financial burden on a societal level. Our assessments will rely on a mixed-method approach combining qualitative analyses in 3 EU countries (interviews with adult survivors of CM (ASCM) and HSC professionals) and quantitative analyses (longitudinal cohort study based on HSC administrative data in 7 countries, but also aggregated CPS data in 26 countries). An interdisciplinary participatory synthesis of the findings (with stakeholders and ASCM) will deliver a co-constructed assessment of the situation and the definition of priority actions. Finally, we will design and promote, through the consortium's extensive network, operationally and economically viable recommendations with potential for transposability across the EU for policy makers and HSC services.The SERENA recommendations will encourage changes in policies in all EU member states so that HSC daily practice can i) be assessed in terms of validity and availability of the services in all areas, ii) identify necessary evolutions to be encouraged through legislative measures (data collection and exchange between HSC services), a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Towards Autonomous Large Area Mass Production Sputtering Plants' under Horizon 2020.

assistant: **Concept**

Problem: Although manufacturing is moving towards full automation, some industries, such as thin film manufacturing industry, are still heavily reliant on inefficient human labor. There are no commercially available solutions on the market enabling full automation of thin film production plants. That explains low production rates, waste of materials & energy, high operating costs, and increased overall inefficiency of thin film industry, which also has a direct negative impact on other industries dependent on using thin film components for goods they produce, such as smartphones, tablets, computers, cameras, watches, jewellery, various medical instruments, and many more.Solution: Nova Fabrica has already successfully developed and tested a prototype of a plant-wide intelligent Supervisory Process Control System (iSPCS) – the only holistic control system, enabling real-time production/process monitoring for thin film plants, thus fully automating the process side of thin film manufacturing. Initial investigations performed by the biggest thin film plant in the Baltics “Groglass” estimated that the iSPCS at its current state could provide their plant a 30% increase in thin film production volumes and up to 10% decrease in electricity consumption (by 1 GWh) leading to an increase in net profits by 54%. In conclusion, if iSPCS was adopted by thin film manufacturers it would produce a profound impact on many industries reliant on thin films on a European and global level.Next steps: Thorough market analysis and an elaboration of a business plan is needed in order to define strategic commercialization. This feasability study will be a crucial step towards commercialisation of iSPCS and needs to be completed urgently due to current conditions of Nova Fabrica being the first co
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Printed SELF-power platform for gas SENSing monitoring' to be submitted under Horizon 2020.

assistant: **Abstract**

The final aim of this project is to develop an autonomous gas sensor system capable of discriminating among different vapour species. Looking at the attractive characteristics of reduced graphene oxide, we should look for their functionalization in order to increase their selectivity to a concrete gas while decreasing it to others. Furthermore, the design of sensor arrays together with pattern recognition algorithms will be investigated in order to develop a highly selective sensory device towards different gas molecules. Moreover, the whole manufacturing of these sensors will be done by printing and laser scribing techniques because of the large amount of characteristics that this technology offers to electronics circuits (e.g. large-scale fabrication, lightweight, flexibility). In addition to this, the sensing layer should be recovered in order to have a fast response of the sensor to force the trapped molecules to escape. This issue will be also addressed compromising time response and power demand. In this project, we propose the inclusion of energy harvesting approach together with a storage element in order to reduce this consumption or even to achieve a self-powered sensory system. A key point of this strategy will be to employ the same fabrication processes as the used for the manufacturing of the gas sensors. Finally, the whole system will be to include it in a larger system, adding the required circuitry and communication module with the aim of performing environmental monitoring in different scenarios such as industry or building comfort. For example, the inclusion of a gas sensing platform can control and adjust the proper work environment conditions. This solution can not only enhance the quality of working conditions but also to reduce cost and pollution,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'High-Power Optical Vortices – From Generation to Application'.

assistant: **Objectives**

The use of high-power optical vortex beams has been predicted to provide substantial benefits to many applications ranging from more precise material processing to advanced particles accelerators. However, progress has been hampered by the absence of approaches for their generation while maintaining their unique properties during propagation and/or interaction with matters. The overall aim of HiPOVor is to train 15 ESRs to be the first generation of a workforce skilled in all aspects concerning the generation of optical vortices with high power and high modal purity and its application as a key enabling technology widely in light-matter interaction aspects. Through the completion of interconnected individual projects in topics all together covering the full development chain, ranging from components suitable for their generation and fundamental aspects of their physical properties, to amplification, propagation in different environments and applications, the doctoral candidates will develop expert skills and knowledge to drive forward the field of high-power optical vortices. The HiPOVor network will address gaps both in terms of technology and applications, and in terms of personnel through the innovative research approaches. The interdisciplinary and intersectoral consortium consists of 8 leading academic institutions in the field of structured light and high-power laser development, the world’s most powerful laser infrastructure ELI-NP, as well as 9 industrial partners, highlighting the high potential of and interest in our project for rapid market uptake. The results of our project promise significant impacts in strengthening Europe’s scientific excellence.  It will enable new products and improved processes, e.g. optical components and nanofabrication, and environm
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Lipid asymmetry: a cellular battery?'.

assistant: **Innovation**

It is a basic textbook notion that the plasma membranes of virtually all organisms display an asymmetric lipid distribution between inner and outer leaflets far removed from thermodynamic equilibrium. As a fundamental biological principle, lipid asymmetry has been linked to numerous cellular processes. However, a clear mechanistic justification for the continued existence of lipid asymmetry throughout evolution has yet to be established. We propose here that lipid asymmetry serves as a store of potential energy that is used to fuel energy-intense membrane remodelling and signalling events for instance during membrane fusion and fission. This implies that rapid, local changes of trans-membrane lipid distribution rather than a continuously maintained out-of-equilibrium situation are crucial for cellular function. Consequently, new methods for quantifying the kinetics of lipid trans-bilayer movement are required, as traditional approaches are mostly suited for analysing quasi-steady-state conditions. Addressing this need, we will develop and employ novel photochemical lipid probes and lipid biosensors to quantify localized trans-bilayer lipid movement. We will use these tools for identifying yet unknown protein components of the lipid asymmetry regulating machinery and analyse their function with regard to membrane dynamics and signalling in cell motility. Focussing on cell motility enables targeted chemical and genetic perturbations while monitoring lipid dynamics on timescales and in membrane structures that are well suited for light microscopy. Ultimately, we aim to reconstitute lipid asymmetry as a driving force for membrane remodelling in vitro. We expect that our work will break new ground in explaining one of the least understood features of the plasma membrane and