RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Anode-Free Li-ion Batteries (AF-LIBs): Investigating Electrochemical Performance and Scalability for Next-Generation Energy Storage' (AF-LIBs), addressing dissemination and exploitation.

assistant: **Impact**

Anode-free lithium batteries (AF-LIBs) have emerged as a promising alternative to conventional lithium-metal batteries due to their potential for higher energy densities, improved safety, and simplified manufacturing processes. However, their rapid development is hindered by poor charge/discharge cycles. This is due to the side reactions of the conventional battery electrolytes to form dead/inactive lithium, thereby leading to dendritic Li plating. I propose to investigate the use of High Concentrated Electrolytes (HCEs) and Multi-salt Electrolytes (MSEs) as novel approaches to achieve a robust and efficient plating and stripping of Li in AF-LIBs. The high concentration and/or presence of additives in these proposed electrolytes can regulate the thermodynamics and kinetics of the Li deposition/striping process, thereby overcoming dendritic Li growth. To achieve this objective, I will prepare novel HCEs, and MSEs and use various in-situ and operando structural and spectroscopic techniques to gain insights into the effects of the electrolyte types (different types of anion and cation) and composition on the lithium deposition and formation of SEI in AF-LIBs. These fundamental insights will facilitate the development of AF-LIBs, which are among the next-generation advanced energy storage technologies that are pivotal to the realization of energy and environmental sustainability.


**Keywords:** Anode-free batteries,  Interphase engineering,  High concentrated electrolytes,  Electrolyte additives,   Artificial interphase engineering,  Lithiophilic host
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Trans-national co-operation among National Contact Points for Marie Curie Actions (People NCP’s)' (PEOPLENETWORK) targeting Seventh Framework.

assistant: **Abstract**

National Contact Points (NCPs) play a crucial role in the Framework Programme as providers of information and assistance to potential participants (applicants) of new projects and contractors in on-going projects. They reach out to the European research community in order to inform and raise awareness about the funding opportunities of the Framework Programme, to advise and assist potential applicants in the preparation, submission and follow-up of grant applications, and to offer support during the execution of projects – especially with respect to the management and administrative aspects of projects. Moreover, due to its closeness to the European research community, the European Commission perceives the NCP Network as an important instrument for gathering feedback on possible problems and difficulties in the implementation of the Framework Programme. One of the great strengths of the NCP system is its national orientation and ability to provide support to applicants in their own native language. This is carried out by experts that are not only well versed in the modalities of the Framework Programme, but, as a rule, also possess keen knowledge of the national research landscape in their respective fields. On the other hand, however, this national orientation poses certain problems. The decentralised system – organised and financed nationally – has led to the development of a collection of heterogeneous structures.  In an effort to address the weaknesses described above, the project proposal PeopleNetwork aims at the development and implementation of a coordination mechanism for stimulating closer cooperation among National Contact Points for the PEOPLE programme in the Seventh Framework Programme. PeopleNetwork will facilitate the improvement of the overall quality o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'Sigma 204 force fill assessment for 0.5 microns contact/via al(0.5 %cu) plug technology in high volume production environment'.

assistant: **Objectives**

- To evaluate performance and cost benefits of the new metalisation technology over the tungsten plug/ aluminium process.- To evaluate the sputter etch - Ti/TiN processes which precede the aluminium deposition and the FORCEFILL process.- To assess and improve the overall equipment performance in a high volume 0.5 micron BICMOS production lineThe performance of the Electrotech SIGMA 204 FORCEFILL cluster tool is to be assessed for 0.5 micron contact/via plug technology (Al/0.5%Cu) in the high volume production environment of Texas Instruments, Freising Germany. The advantages of this aluminium FORCEFILL technology over the presently employed tungsten plug and aluminium process has to be demonstrated under manufacturing conditions. The complete metalisation process sequence is: Sputter etch - Ti/TiN - Al/0.5%Cu - FORCEFILL.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'miRNASTRESS: structural and functional study of the RBM38-controlled mechanism of mRNA stabilization.' (MIRNASTRESS) under Seventh Framework.

assistant: **Objectives**

The aim of the research activities detailed in this proposal is to understand how the RNA-binding protein RBM38 mediates the cellular stress response —the series of cellular events triggered by diverse harmful factors to restore cellular homeostasis— by modulating the activity of microRNAs  on specific targets. Our objective is to determine the molecular mechanism by which RBM38 interferes with the binding of miRNAs on a selection of messenger RNAs that are targets of the tumor suppressor p53, a protein which guards the genomic integrity and regulates the stress response. The normal cellular stress response is crucial to restore or reprogram various gene-expression patterns that maintain homeostasis. Failure in this response can lead to severe pathological conditions, such as cancer. Understanding the mechanisms that mediate the stress response at the molecular level is thus one of the most important open questions in cell biology today and has a clear impact in molecular medicine and in the pharmaceutical industry.We will use state-of-the-art biophysical techniques to identify the molecular and biophysical basis of RNA recognition by RBM38. We will propose a mechanism to explain how RBM38 controls post-translational gene expression through the inhibition of miRNA activity. Our research will provide the molecular rationale for a key mechanism of cell regulation and will advance our knowledge of the biology involved in the development of cancer. miRNASTRESS will address a gene-regulation mechanism based on the interference of miRNA activity and will provide the necessary structural information to tune the activity of RBM38. Building on our study and on the know-how accumulated on RNA recognition motif-RNA interactions, we aim to use the RBM38 high-resolution structure as
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Informal Media Economies' (IME).

assistant: **Innovation**

The aim of this proposal is to study the conflicts between different stakeholders about the future of intellectual property regulation. At the moment there seems to be an irreconcilable difference between bottom-up social norms governing informal media economies (copynorms) and top-down copyright regimes. This project plans to map the values, norms and self-regulatory approaches of individuals and online communities participating in exchanges in informal media networks to guide and inform policy formulation and possible shift in the formal regulatory frameworks. A better understanding of the bottom-up means of creating, protecting, using of intellectual properties may help to close the aforementioned gap and result in a more egalitarian, commonly accepted and up to date system of copyright regulation.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Development of simple to use point of care tests for zoonotic pathogens and their validation for use in clinical research setting' (ZOONOMARKS) under Horizon 2020.

assistant: **Objectives**

Our major goal is development of simple to use point of care tests for zoonotic pathogens and viral hemorrhagic fevers (VHF), and their validation for use in clinical research setting. Zoonosis is any process whereby an infectious disease is transmitted between different species of animals. The term zoonosis is here used specifically to refer to diseases that originate in other species of animal, but that get transmitted to humans. Zoonoses in which humans are infected may originate in either domestic animals or wildlife, such as insects, mammals, reptiles, bats, or birds. This application contains a draft business plan with feasibility study that verifies the technical and economic viability of the new diagnostics in the proposed clinical validation.In phase 1 a comprehensive business plan will be produced aiming in phase 2 to develop a comprehensive rapid response diagnostic system for zoonotic pathogens and hemorrhagic fever viruses, with implications for surveillance of all emerging pathogens. Furthermore, in phase 2 the developed tests will be evaluated by end users of the tests – by several research and clinical diagnostic laboratories.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Transplantation of magnetic-labelled vascular cells and cardiomyocytes isolated from human embryonic stem cells in a bioactive injectable gel for myocardium regeneration after infarct' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

Cardiovascular diseases remain the number one cause of death in the western world. Human embryonic stem cells (hESCs) represent a promising source of cells for the treatment of cardiovascular diseases because of their unlimited cell propagation and ability to give rise to different cell types, including cardiomyocytes, endothelial and smooth muscle cells. Cardiomyocytes isolated from hESCs have been shown to form new myocardium after infarct; however, the functional recovery of the myocardium was low and the functional coupling was inexistent since the cardiomyocytes were observed within the scar and not in direct contact with host cardiomyocytes (Laflamme et al., Nat Biotechnol 2007). So far, no studies have reported the benefits of prevascularizing cardiomyocyte cell constructs to enhance in vivo cell viability, grafting and functional coupling. Additionally, we anticipate that the transplantation of these cells using an injectable bioactive gel will enhance cell retention and viability at the injection site. This projects aims at evaluating the neovascularization and myocardium functional recovery after transplanting hESC-derived cardiomyocytes and vascular cells into a myocardial infarction animal model. Recently, we isolated endothelial and smooth muscle cells from hESCs that form microvessels when injected subcutaneously in nude mice and thus might be an important cell source for the vascularization of the myocardium. In addition, this projects aims at developing a bioactive injectable gel to function as a temporary three-dimensional scaffold and a protocol to monitor non-invasively in vivo cell grafting.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Universal Gasification Process Analyser for Bio Mass and Organic Waste Treatment' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

One of the most promising “green processes” for power and combined heat generation is the production of hydrogen and biogas by gasification of biomass or organic waste. Especially if the tremendous amount of existing organic waste can be used for gasification, these processes become both, ecologically and economically extremely interesting. Gasification processes are performed under elevated or high temperatures and ambient or elevated pressures. A special gasification and evolved gas refinery treatment becomes indispensable if different kind of organic waste will be used. Therefore many new processing treatments have to be developed which will constitute a rising demand for laboratory scale gasification process analyzers as well as in Situ high temperature concentration sensors. The goal of this project is a new laboratory gasification process analyzer including several new in Situ high temperature concentration sensors for process application in a broad temperature and pressure range. The analyzer consists of a gravimetric pyrolyzer to determine the time dependent reaction rates of gasification processes under industry-oriented conditions and a following catalyser unit for gas refinery treatment investigation. For high temperature concentration sensors different optical methods like UV/VIS, NIR, Raman and FTIR spectroscopy will be applied and several electro ceramic and piezo electric sensors for impedance, thermal conductivity, heat capacity, VOS and calorific value will be developed. This project will educe an universal gasification processes analyser allowing an experimental simulation of industrial gasification processes in laboratory scale and providing various kind of high temperature sensors for process use at all scales. It will be an essential step to optimis
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'A portable MicroNanoBioSystem and Instrument for ultra-fast analysis of pathogens in food: Innovation from LOVE-FOOD lab prototype to a pre-commercial instrument'.

assistant: **Objectives**

The development of new methodologies advancing the state of the art in foodborne pathogen detection is a challenge for scientists and technologists as well as food industry and consumers. This project aims to meet the challenge by providing a reliable and versatile solution thanks to the convergence of micro-nano-bio systems. The work capitalizes on several innovative concepts which have already been proven to meet the required criteria for fast, low cost and highly sensitive analysis of pathogens in food samples in a previous research project entitled LoveFood.These concepts are gathered on a credit-card size Lab-on-Chip platform, where all necessary steps for bacteria detection are performed on several chips. Specifically, bacteria capture and lysis (one chip), DNA extraction (second chip) and amplification (third chip) and finally pathogenic-DNA detection (fourth chip) can be performed in less than 8 hours and without the need for skilled personnel or large, lab-based dedicated equipment. To proceed for a higher Technology Readiness Level towards the successful commercialization of the current prototype and produce a portable, and rapid platform (targeting total pathogen analysis time 4 hours including a 3 hour pre-enrichment step), we propose to further develop it by integrating the bacteria lysis, DNA purification and amplification modules, as well as the biochip detection platform on a single cartridge, able to perform multi-pathogen analysis (i.e. Salmonella, Listeria, Escherichia coli and Bacillus cereus) in multiple samples. The system will be developed for dairy products and meat analysis, with a strong commitment to produce a pre-industrial prototype by the end of the project.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'The P2X7 receptor as treatment target for traumatic brain injury-induced epilepsy' in the context of a Horizon Europe call.

assistant: **Objectives**

Post-traumatic epilepsy (PTE) is one of the most common, devastating complications following traumatic brain injury (TBI), and is particularly prone to drug-refractoriness. Critically, current anti-seizure medication remains ineffective in over 30% of patients, with no impact on disease progression and frequent adverse side effects. Increasing evidence suggests inflammation as one of the main contributors to the development of PTE. ATP, released during pathological processes in the brain, functions as an important extracellular signalling molecule driving inflammatory processes via the activation of the ATP-gated ionotropic P2X7 receptor (P2X7R). Increasing evidence suggests that targeting of the P2X7R provides potent anticonvulsive effects and, possibly, disease-modification during epilepsy. Whether P2X7R antagonism prevents the development of PTE has not been investigated to date. My planned research will 1) investigate the disease-modifying potential of targeting the ATP-gated P2X7R on TBI-induced epilepsy and associated comorbidities, thereby sparing patients from life-long drug dependency, and 2) evaluate the potential of P2X7R-based PET imaging as novel patient stratification tools to identify patients at risk of developing PTE for an earlier and more effective treatment start. EpiPrevent brings together a team of experts in purinergic signalling, industrial partners developing novel P2X7R antagonists and clinicians specialised in epilepsy. This highly interdisciplinary and intersectoral approach will add a significant contribution to the understanding of purinergic signalling during TBI, providing novel diagnostic and therapeutic approaches. The skills acquired during the research project, the excellent training record of the supervisor and host institution and t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Energy savings from advances emergency lighting powered by cadmium free cells', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

The project will develop environmentally friendly emergency lighting systems, incorporating a low energy light source based on light emitting diodes or light emitting polymers. It will also utilise a rechargeable cell to replace the nickel cadmium cells commonly used in exit signs. These two innovations will improve the environmental performance of this large sector of the lighting market, leading to reductions in greenhouse gas emissions and the elimination of cadmium, a toxic pollutant. Other benefits for the user will arise from the longer operational life of the solid-state light source. Prime propose Orbit Electronics Ltd is a UK SME specialising in electronic drive gear for fluorescent and emergency lighting fittings.