RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'New techniques to avoid expansion due to air moisture in building ceramic materials' (1994-1998) targeting Fourth Framework.

assistant: **Abstract**

The expansion due to air moisture is a phenomenon produced in manufactured baked clay pieces. The cited phenomenon lies in the environmental moisture absorption by the materials that constitute the ceramics pieces. This absorption causes a slight dimensional increase of a ceramics piece that it could generate several pathologies in the buildings. Moisture expansion effects (e.g. crackings, fissures, etc) appear especially in the hollow clay blocks for floor and in the bricks for façades . The mechanism by which ceramic materials expand when absorbing moisture is not perfectly known yet. It is supposed that porosity and proportion between amorphous and crystalline phases of the ceramic piece are the most important variables involved. The goals of research are the study of inclusion of special additives, in order to modify the internal structure of ceramics piece and the influence of baking parameters.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Microscopy of living cancer cells at physiological oxygen levels: the MICROX platform' under Horizon 2020.

assistant: **Concept**

Functional evaluation of bioactive compounds using cell-based assays is key in discovering new and improved drugs to address our societies growing medical needs. In a large number of academic and private R&D facilities around the world, hi-content microscopy screening is used to complement and often outperform the conventional luminescence and fluorescence plate-reader assays. The combination of fluorescent-probe technology, modern optical microscopes and innovative functional assays allows monitoring highly dynamic events in living cells with exquisite temporal and spatial resolution.Remarkably, drug candidates and treatment regimens are commonly tested on living cells maintained at atmospheric oxygenation levels (i.e., at 21% O2) while in reality, cells in our bodies never experience such high oxygen levels. Rather, most cells experience 2-5% of O2 and cancer cells in solid tumours are generally hypoxic, i.e., they function at < 1% of O2. It has become evident that oxygenation of the preparation dramatically affects efficacy of our drugs, in particular of cancer treatments. Thus, there is an urgent need to establish functional microscopy assays for (cancer)drug efficacy at hypoxic conditions. However, it is not trivial to enclose the necessary high-end microscopes in O2-tight incubators while maintaining good access to the cells. In this project, experienced biochemist and pharmacologist dr. Olga Mazina aims to team up with the advanced microscopy group of prof. Kees Jalink to establish an innovative MICROX microscopy platform with fully adjustable atmospheric conditions, along with a panel of biosensors optimized for use at hypoxia. MICROX will be developed in close collaboration with leading European manufacturers and validated in studies addressing cancer cell sign
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Software Workbench for Interactive, Time Critical and Highly self-adaptive cloud applications' (SWITCH).

assistant: **Concept**

The SWITCH project (Software Workbench for Interactive, Time Critical and Highly self-adaptive Cloud applications) addresses the urgent industrial need for developing and executing time critical applications in Clouds. Time critical applications such as disaster early warning, collaborative communication and live event broadcasting can only realise their expected business value when they meet critical requirements for performance and user experience. The very high requirements on network and computing services, particularly for well-tuned software architecture with sophisticated data communication optimisation, mean that development of such time critical applications is often customised to dedicated infrastructure, and system performance is difficult to maintain when infrastructure changes. This fatal weakness in the existing architecture and software tools yields very high development cost, and makes it difficult fully to utilize the virtualised, programmable services provided by networked Clouds to improve system productivity. SWITCH aims at improving the existing development and execution model of time critical applications by introducing a novel conceptual model (application-infrastructure co-programming and control model), in which application QoS/QoE, together with the programmability and controllability of the Cloud environments, can all be included in the complete lifecycle of applications. Based on this conceptual model, SWITCH provides an interactive environment for developing applications and controlling their execution, a real-time infrastructure planner for deploying applications in Clouds, and an autonomous system adaptation platform for monitoring and adapting system behaviour. The SWITCH consortium has well-balanced partners with complementary expertise
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Molecular genetics of stress response and meat quality in pigs' under Fifth Framework.

assistant: **Concept**

Comparison of biological stress responses in the five main breeds used in European pig production, as related to meat quality. Investigation of the molecular mechanisms explaining the genetic variation in stress hormone secretion and carcass composition.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'The germline mutational landscape of chronic lymphocytic leukemia' to be submitted under Seventh Framework.

assistant: **Abstract**

Chronic lymphocytic leukemia (CLL) is a cancer of B-lymphocytes, which expands in the bone marrow, lymph nodes, spleen and blood. While many genes have been implicated in CLL development through sequencing the genome of tumor cells, they do not completely explain the pathogenesis of the disease, nor define the early events that lead the B-cells to proliferate and become cancerous, accumulating the different types of somatic mutations of CLL. Most sequencing studies have focused only on discovery of somatic mutations without investigating germline risk variants. The aim of this project is to identify the landscape of germline risk factors that can predispose an individual to CLL. We will utilize whole-genome and exome-sequencing data on 100 and 500 CLL cases (normal and tumor samples) respectively, from the Spanish CLL consortium (International Cancer Genome Consortium). We will identify recurrent predicted damaging germline mutations. The results from relevant genes will be replicated in a larger cohort of cases and controls. The 20 most important genes accumulating damaging germline mutations in CLL patients (preliminary results involve cell-cycle, DNA damage checkpoint, double-strand break repair genes) will be tested at the functional level to evaluate the nature of the biological processes that are enriched in CLL. We will either use Saccharomyces cerevisiae or cell lines as model systems for functional analyses of the selected genes. We will also then implement other systems, such as Caenorhabditis elegans or Danio rerio models, for which convergent data on mutations in the altered pathways have been obtained. We expect to identify the complete spectrum of susceptibility genes involved in the early stage of development of this type of leukemia and advance the under
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Inter-cluster initiative to target the future challenges for the European polymer converting industry' in the context of a Seventh Framework call.

assistant: **Objectives**

In order to set-up and implement coherent economical development strategies, it is essential for the European Polymer Converting Industry to structure and support its economical development on the basis of its local/regional clusters. CLUSTERPLAST will aim to achieve such a goal through the setting-up of a Joint Action Plan dedicated to support actions common to 6 European regions. The project will make profit from the experience of 4 existing research-driven clusters. These clusters all comprise the triangle research – business – local/regional authority acting as motor of the cluster activities. CLUSTERPLAST will make profit from the experience of these 4 existing clusters by promoting the creation of 3 new clusters.A review on the main actors in the Business, Research and Regional/Local authorities, on R&D financial instruments, Technology Roadmaps, Projects and Initiatives will support an increased awareness, the furthering of networking of dissemination activities, the technology transfer between regional entities and clusters, and the launch of joint initiatives and projects. This review will further enable the benchmarking and the identification of best practices and its dissemination between clusters. The increased awareness will also support the identification of further opportunities, cross actions and a further interaction between the entities of the Innovation system, providing for: (1) a proficient use of the available capacities, competencies and knowledge at European scale; (2) an efficient selection and resort to funding instruments; (3) the further valorization of R&D results. In this framework, the development of a Joint Action Plan will constitute the major deliverable towards this end. In last analysis, these initiatives will address to the furtherin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Micro Market Experience'.

assistant: **Innovation**

The retail world is going through a period of strong evolution, accelerated by the ongoing COVID-19 pandemic. E-commerce has been shown to be a pillar of society and through necessity it outperformed physical shop retail in many product sectors, e.g. electronics, books. To cope with new social distancing measures being enforced by nearly all countries, in the near future traditional bricks-and-mortar retailers must introduce innovations that can help them to maintain their profit margins and support customers’ choice, access and most importantly their employees’ safety. Shoppers are demanding reduced waiting times, the possibility of buying a greater variety of products when they want them, i.e. 24-hour opening hours, and to feel safe when shopping. The solution we have developed in MiMEX, using intelligent shelves, and connected smart spaces targets these problems and opportunities. We propose to automate social distancing checks and adhere to regional safety protocols (such as wearing gloves and masks). We will exploit deep-learning algorithms and low-cost sensors to answer product choice and availability needs. We will create a complete hardware & software micro-market solution that can monitor shoppers’ safety and simultaneously track products/goods collected by customers in real-time inside a store, facilitating smart and safe checkout with bespoke payment systems. A complete monitoring system will make it possible to offer high-value services such as exhausted product alarms, attempted thefts or display-shelf tidying requests to retailers.


**Keywords:** Micro market,  object detection,  people tracking system
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Decrypting the role of bacterial signals in microbial interactions to enhance  Lysobacter establishment in the rhizosphere' to be submitted under Horizon 2020.

assistant: **Abstract**

Bacterial biocontrol agents (BCAs) are a promising alternative to chemical pesticides in sustainable agriculture. However, their use is often inconsistent in field, mainly due to the difficulty of BCAs to effectively colonize the rhizosphere and integrate in resident microbial communities. As invaders, BCAs have to face indigenous microbiota once arrived on the rhizosphere, and the establishment of interspecific interactions based on quorum sensing (QS) signals may enhance or hinder their establishment in the rhizosphere. With the objective to solve the problem of BCA inconsistency in field, our research is aimed at unveiling the response of a model BCA to main QS signals released by rhizosphere-living bacteria. To do that, we designed a straightforward working plan based on the combination of microbiology, transcriptomics and formulation technologies. We will use Lysobacter capsici AZ78 (AZ78) as model BCA and QS signals already characterized in rhizosphere-living bacteria. Firstly, we will identify main QS signaling systems included in AZ78 genome through genome mining and we will dissect the AZ78 transcriptional response to QS signals through RNA-Seq. Concurrently, we will identify bacterial strains living on tomato rhizosphere able to boost the AZ78 capacity to release antibiotics and resist UV-light, thanks to positive interactions. Finally, we will develop novel formulations of bacterial consortia (AZ78 with helper bacterial strains) incorporating also positive QS signals. The outcome of this project will be a milestone in the development of next generation BCAs relying on the interspecific interactions to favor BCA establishment in the rhizosphere. The achievement of the results will allow me to create a research group focusing on the ecology and formulations of
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Agricultural Revolution in Southern Europe?' (ARISE) targeting Seventh Framework.

assistant: **Abstract**

ARISE will provide a detailed survey of the dietary status of Southern Europe’s prehistoric inhabitants in order to examine key issues relating to the transition to farming in this region. The domestication of plants and animals and the spread of ways of life based on these resources was one of the most important events in human history. In Sothern Europe, there is good archaeological evidence for cereal cultivation and animal husbandry between 9,000 to 7,000 years ago; practices that can be traced to their origin in the Near East over a millennia earlier. However key questions remain unanswered or are keenly disputed: Was it a rapid event or a series of drawn-out processes? Did farming arrive as a complete package or were some elements introduced earlier than others? Was this process driven by the movement of people or of ideas?   Recent methodological advances in molecular biology and mass spectrometry have provided new analytical tools that are now available to address these questions. Stable isotope analysis of human bones and chemical analysis of food remains on archaeological artefacts have provided spectacular insights into changes in human diets and subsistence practices. However, these have only been applied to sites in Northern Europe; the South has been surprisingly neglected. To re-address this balance, ARISE will apply these state-of-the-art methodologies to bones and artefacts from some of the most important early agricultural sites in the Mediterranean in order to produce a new synthesis of the origins of agriculture in this region.  Additionally, ARISE will provide the potential for long-lasting collaboration between the applicant’s new and previous host departments (Universities of York & Rome) and promote his transition to independence as he establishe
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Early life imprinting of B cell memory and its role in adult immunity'.

assistant: **Concept**

This proposal addresses the combined role of early life derived B cells in the adult immune system. Neonatal immune imprinting is now well-established concept. It emphasizes the importance of the early life window to establish host-microbial mutualism and the set-point for immune responsiveness later in life. However, the cellular and molecular mechanisms underlying this immune programming are not well understood. Despite the ability of B cells to integrate and store complex immunological memory for a lifetime, surprisingly little is known about its ability to confer the longitudinal effects of neonatal microbial instruction.By time-stamping B cells that arise early in life, my research team resolved a self-sustaining network of IgM and IgA B and plasma cells that carry memory of neonatal exposure. Such early life origin B (ELO-B) cells are unevenly distributed among immunophenotypically and anatomically defined B cell subsets and make up a substantial portion of the adult B cell pool in unimmunized mice. These findings reveal pervasive neonatal antigenic imprinting of the adult B cell compartment, challenging the assumption that the adaptive immune system is naïve in the absence of deliberate immunization. With this understanding arises an urgent need to dissect the formation and function of ELO-B cell memory and their lasting impact on host protection and long-term homeostasis. To this end, we have built an unprecedented genetic toolkit leveraging the power of our time-stamping approach, to track and manipulate ELO-B cell responses without perturbing adulOverarching hypothesis: ELO-B cells uniquely imprinted by developmental and microbial determinants early in life shape the trajectory of adult immune responses in health and disease.Aim 1. Dissecting the formation of
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'The role of consciousness in adaptive behavior: A combined empirical, computational and robot based approach""'.

assistant: **Concept**

Understanding the nature of consciousness is one of the grand outstanding scientific challenges and two of its features stand out: consciousness is defined as the construction of one coherent scene but this scene is experienced with a delay relative to the action of the agent and not necessarily the cause of actions and thoughts. Did evolution render solutions to the challenge of survival that includes epiphenomenal processes? The Conscious Distributed Adaptive Control (CDAC) project aims at resolving this paradox by using a multi-disciplinary approach to show the functional role of consciousness in adaptive behaviour, to identify its underlying neuronal principles and to construct a neuromorphic robot based real-time conscious architecture. CDAC proposes that the shift from surviving in a physical world to one that is dominated by intentional agents requires radically different control architectures combining parallel and distributed control loops to assure real-time operation together with a second level of control that assures coherence through sequential coherent representation of self and the task domain, i.e. consciousness. This conscious scene is driving dedicated credit assignment and planning beyond the immediately given information. CDAC advances a comprehensive framework progressing beyond the state of the art and will be realized using system level models of a conscious architecture, detailed computational studies of its underlying neuronal substrate focusing, empirical validation with a humanoid robot and stroke patients and the advancement of beyond state of the art tools appropriate to the complexity of its objectives. The CDAC project directly addresses one of the main outstanding questions in science: the function and genesis of consciousness and will a