RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Scanning Policy Scenarios for the Transition to Sustainable Economic Structures' (2002-2006), addressing dissemination and exploitation.

assistant: **Impact**

The focus of this research project will be to scan a wide range of policy scenarios as to their relevance for the European Sustainable Development Strategy in view of Extended Impact Assessment. Embedded in the TranSust network of researchers, with its expertise in modelling the transition to sustainable economic structures, the project will link and expand an extensive set of available models. Using a scenario approach in cooperation with stakeholders, these models will address the strategic policy options.In a first step, existing models will be extended to reflect the multi-functionality aspect of sustainability policies and their trade-offs with other policies. In addition to the traditional economic, environmental and social issues, the expanded models will address the new policy agenda as put forward by the Lisbon Strategy of the European Union and the World Summit for Economic Development. The models will therefore be able to deal with competitiveness, economic development, security, the preparations for Beyond-Kyoto policies, and interaction between technological change and the use of natural resources.In a second step, this enhanced set of models will be used for a comprehensive analysis of a wide range of policy scenarios. In designing the scenarios, a participatory approach will emphasise close cooperation with stakeholders, Commission services, and international organisations. By back-casting the path dependency and by simulating the range of assumptions, the scenario analysis will reveal the sensitivity of forecasts.The methodology and databases will be made available to institutions involved in policy decision-making. TranSust.Scan aims to enhance European competence and expertise for dealing with the emerging extended facets of sustainability and their im
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Mobilising the World: A New History of Inter-Allied Cooperation in the Second World War, 1939-1945'.

assistant: **Objectives**

In the Second World War, the Allies waged war on a truly global scale for the first and, one hopes, last time in history. Victory required themobilisation and transportation of wo/men and materiel on all continents and across four out of the Earth’s five oceans. Success would have been impossible without extensive inter-Allied coordination, organisation and planning. Starting in 1939, a system of inter-Allied organs was set up by Britain and France, whose mission it was to coordinate the supply of the Allied war effort from a common pool. It survived France’s fall in 1940 and, upon US entry in 1941, was revived. By 1942, it had evolved into a global network of military, production and logistics experts from India to Canada and South Africa to Norway, organised into a series of so-called Combined Boards and dedicated to the nuts and bolts of worldwide coalition warfare. Yet we lack a history of this extraordinary organisation. Despite the Second World War’s self-evidently global nature, the tendency to frame it in national, comparative and Eurocentric terms is very deeply entrenched. INTERALLIED, by contrast, seeks to highlight the global, transnational and interdependent character of the Allied war effort. The project asks: how did the Allies seek to couple, then uncouple their war economies, and mobilise (then demobilise) global markets for war, between 1939 and 1945? It seeks (1) to provide an account of the political economy of global Allied warfare, and thus to reach for a history of the global economy at war, which has yet to be written; (2) to advance a recent 'global turn' in Second World War studies, and thus to resist nationalistic and Eurocentric readings of the conflict, frequently deployed politically today; and (3) to produce new, practical knowledge about
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Cannabinoid receptors CB1 in schizophrenia: role of brain mitochondrial activity and astroglial signalling' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Schizophrenia is a severe psychiatric disorder characterized by a series of ""positive"" and ""negative"" symptoms, which eventually lead to strong sufferance, social isolation and occupational impairment. Via activation of type-1 cannabinoid receptors (CB1), cannabinoids are known to induce schizophrenic-like symptoms, which are major caveats in the possible therapeutic use of these compounds. On the other hand, mitochondria-dependent regulation of brain bioenergetics is emerging as a promising novel research path in the field of psychopathology of schizophrenia. Previous results suggest the implication of mitochondrial (mtCB1) and astrocytic-CB1 receptors in psychotic-like conditions. However the precise molecular and cellular links between ECS activity and schizophrenia are not known. The aim of this study is to test whether mithocondrial and/or astrocytic CB1 receptors represent a functional link between endocannabinoid signalling in the brain and psychotic-like behaviours. (1) Firstly, the project will be dedicated to the generation of specific genetic tools to clearly discriminate mtCB1 from other CB1 receptor locations in the cell. (2) Then, these specific tools and specific transgenic mice will be used to investigate the role of mtCB1 and astrocytic-CB1 receptor in ""psychosis-like"" effects of cannabinoid drugs, and (3) to study the role of these receptors in a schizophrenia-like mouse model. This project will improve our understanding of the pathophysiology of psychotic-like disorders and might pave the way to novel therapeutic opportunities to improve the life of patients.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Engineering and control of biological systems: a new way to tackle complex diseases and biotechnological innovation' (COBIOS), addressing dissemination and exploitation.

assistant: **Impact**

The aim of this proposal is to engineer a synthetic biological network for in vivo regular therapeutic delivery of insulin in a rhythm corresponding to normal nutrient uptake. To this end, we will engineer stable synthetic oscillator networks in yeast and mammalian systems able to express mRNA/protein levels with a pre-determined frequency and amplitude.The synthetic oscillator network has to guarantee stable and synchronized oscillation in the cell population. The yeast system will be used as a test-bed for the synthetic biology design strategies developed in this project. In the context of the mammalian tissue, individual cellular oscillators have to be synchronized in order to fulfill the macroscopic function of an insulin delivery device. Hence, the engineering of the synthetic network involves additional inputs and outputs that enable resetting of the oscillators.In view of therapeutic application, the desirable system would reset insulin oscillations synchronously with the circadian rhythm. Specifically, the synthetic oscillator in the mammalian system will be connected to circadian signals like PER1 and CRY. To achieve this aim, COBIOS brings together scientists from yeast and mammalian molecular biology, computer science, engineering and control theory. We will employ methods from systems dynamics and control theory to develop and implement modular control networks that enable oscillations in the networks they will be connected to.In particular, we will address the problems of- robustness of controller dynamics,- suitable interfaces to the controlled networks, and- mechanisms for regulation of the controller's dynamic characteristics (e.g. period and amplitude) through external signals that can be exogeneous (yeast system) or outputs of cellular signal processin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Next-generation Detection of Antigen Responsive T-cells' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Our current ability to map T-cell reactivity to certain molecular patterns poorly matches the huge diversity of T-cell recognition in humans. Our immune system holds approximately 107 different T-cell populations patrolling our body to fight intruding pathogens. Current state-of-the-art T-cell detection enables the detection of 45 different T-cell specificities in a given sample. Therefore comprehensive analysis of T-cell recognition against intruding pathogens, auto-immune attacked tissues or cancer is virtually impossible. To gain insight into immune recognition and allow careful target selection for disease intervention, also on a personalized basis, we need technologies that allow detection of vast numbers of different T-cell specificities with high sensitivity in small biological samples.I propose here a new technology based on multimerised peptide-major histocompatibility complex I (MHC I) reagents that allow detection of >1000 different T-cell specificities with high sensitivity in small biological samples. I will use this new technology to gain insight into the T-cell recognition of cancer cells and specifically assess the impact of mutation-derived neo-epitopes on T cell-mediated cancer cell recognition. A major advantage of this new technology relates to the ability of coupling the antigen specificity to the T-cell receptor sequence. This will enable us to retrieve information about T-cell receptor sequences coupled with their molecular recognition pattern, and develop a predictor of binding between T-cell receptors and specific epitopes. It will ultimately enable us to predict immune recognition based on T-cell receptor sequences, and has the potential to truly transform our understanding of T cell immunology. Advances in our understanding of T cell immunolog
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Automated Assessment and Certification Compliance of Organisations, Systems, Data and AI Operations in a Human Understandable Context' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

ACCOMPLISH aims at increasing the readiness of enterprises of any size to face an era of unprecedented regulatory scrutiny by simplifying, integrating and automating compliance in their data/AI operations, their data/AI assets, their solutions and eventually their overall organisations. ACCOMPLISH will deliver a novel AI-based compliance and certification framework cross-cutting the regulatory/legal, environmental, cybersecurity and business/industry-specific compliance perspectives to modernise, automate and trace the compliance and certification processes with the help of open-source, well-defined and extensible compliance policy models while always ensuring a human-in-the-loop (HITL) approach explaining the compliance requirements and results, as well as proactively alerting about any potential risks/violations. Through the ACCOMPLISH Compliance Digital Passport, the previously “static” compliance and certification assessments will be transformed into up-to-date compliance proof that effectively promotes transparency and accountability for any interested stakeholder. ACCOMPLISH shall also deliver inherently-compliant data economy enablers for Data/AI operations, as reliable mechanisms to design, execute, and trace/observe the data and AI/ML pipelines, as well as to monitor/control their outputs (in terms of datasets, ML/DL models, analytics results). In order to demonstrate the actual innovation and added value that can be derived through the ACCOMPLISH advancements, the ACCOMPLISH results will be validated: I. Through their actual application to address real-life problems in four representative industries that are characterised by a varying maturity level of data/AI operations and compliance: (a) Energy, (b) Automotive, (c) Robotics & Manufacturing, and (d) Aviation
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fifth Framework proposal on 'Quality improvements in moulded footwear'.

assistant: **Concept**

Footwear manufacture in the EU faces severe competition from imported products from third world countries and it is thus essential that production efficiency is maximised while production costs are minimised. Shoe manufacture using sophisticated process machinery and small numbers of operatives can be done in a number of ways, but the most technically advanced of these involves moulding the sole directly onto the bottom of the lasted upper in a direct injection process. This requires several open loop processes, which are not sufficiently accurate to meet the dimensional requirements of the moulding process. This results in relatively high levels of finished shoes requiring re-work, scrap or customer-replacement, representing a major manufacturing cost penalty. This project seeks to overcome these manufacturing defects and hence the associated costs, by exploiting recent advances in non-contact sensing and measurement technologies, to incorporate real-time, closed loop process control.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Innovative Solutions across the MEDiterranean for mitigation of Climate change-related heaLth rIsks and enhancing health systeM resilience'.

assistant: **Concept**

ISMED-CLIM aims to engage and mobilise regional stakeholders across the Mediterranean, in implementing a wide array of adaptation solutions to mitigate the health effects of climate change, and provide evidence for their feasibility, user acceptance and efficacy. Specifically, ISMED-CLIM will (i) enhance the understanding of climate change effects on non-communicable diseases (NCDs) and vector-borne infections across representative European countries within the Mediterranean; (ii) quantify, for the first time, how public health interventions integrating state-of-the-art technologies, public and social media, with vulnerable citizens’ participation can reduce personal exposures to heat and air pollution and related health effects; (iii) validate the feasibility and user acceptance among high risk professionals of a regional early warning and risk prediction tool to mitigate the risk posed by exposure to sand flies and related diseases; (iv) employ open, participatory, and co-creative methodologies to locally adapt and refine existing evidence-based practices and prototype tools to increase the preparedness and ability of health systems in the Mediterranean to deliver safe, effective, and efficient care to citizens. We will test the proposed demonstration solutions initially in eight sites and coordinate ten replications in six sites in five European countries (Cyprus, Greece, Italy, Spain, Portugal), in alignment with Climate Change Adaptation Mission objectives. We will integrate the produced knowledge from epidemiology, forecasting, exposure and health data with insights from the demonstration and replication activities into a knowledge portal and policy decision-centric and action-oriented dashboard for policy makers, healthcare administrators, professionals and citiz
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Integrated Approach for NVH Engineering of Low Weight Vehicles Chassis' under Fourth Framework.

assistant: **Concept**

Objectives and content The comfort of the occupants is one of the major objectives of automotive design. Among the various aspects that form the overall perception of comfort in a vehicle the isolation from noise and vibration is particularly important because it affects also the drivers efficiency. Today every car manufacturer has developed and uses methodologies for the NVH (Noise, Vibration, Harshness) analysis and testing that have substantially contributed to the improvement of the NVH performances of the European vehicles in the past years. Many research activities are actually running aiming at further improvements of these methodologies and some of them under E.C. funding. The new scenario of Low Weight Vehicles (in view of the strict emission, fuel consumption and noise constraints arising in Europe, Japan and US) creates the need for a substantial step forward. The long term aim of cutting down the fuel consumptions at one third of the actual values (that means a weight reduction from 20 to 40% according to PNGV in the US or to EUCAR Master Plan in Europe), while meeting the same levels of customer satisfaction pushes towards innovative design solutions and methodologies tackling new challenges such as the following: - elimination of traditional trade-offs between NVH and weight such as structural reinforcements and fittings - isolation of increased levels of road induced vibrations due to low rolling resistant tires - use of innovative materials and technologies for vehicle structures for which there is limited experience, knowledge based design criteria and engineering data bases - reduction of lead time and prototyping constraints. The need for new design approaches for the NVH of the Low Weight vehicles originates then from the impossibility to rely on car
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Taming the Leviathan? Legal and Political Accountability in 'Post-Crisis' EU Economic Governance' to be submitted under Horizon 2020.

assistant: **Abstract**

The Euro Crisis has had a transformative effect on the functional ambitions of the EU. It has, also, however, transformed the ways in which citizens can hold the EU institutions accountable. In the area of economic governance in particular, the post-crisis EU has created a significant new body of fiscal rules, managed largely by executive institutions. The nature of these rules, and the institutions entrusted to manage them, challenges our existing scientific understanding of accountability, creating considerable confusion among citizens as how economic decision-making in an EU context can be properly scrutinized.  This project is devoted to addressing EU economic governance's 'post-crisis' accountability challenge. It will provide the first comprehensive and multi-disciplinary attempt to consider how EU decisions in the economic field can be challenged, either by political institutions or by individuals seeking judicial review. In doing so, it will seek to move beyond the disciplinary segmentation and conceptual limitations of current academic debates about accountability, combining legal analysis of decisions of national and EU Courts in economic governance with qualitative research on the political and functional constraints within which institutions reviewing economic decisions operate.  The project will also carry a crucial normative dimension, using case studies in important fields of economic policy - from banking regulation to the coordination of national budgets - to map emerging accountability relationships and build recommendations on how to approach post-crisis accountability. Given the reach of EU economic governance into almost all domains of national policy, as well as the declining levels of public trust in EU action, identifying how a more accountable s