RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Quantification of the effect of human-induced environmental change on geomorphic activity' (1998-2002).

assistant: **Concept**

The project aims to quantify the human impact on geomorphic activity on a larger spatial and temporal scale. A new measurement technique based on cosmogony 10Be in river deposits will be tested and its application in mountain areas will be evaluated.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fifth Framework proposal on 'Smoke aerosols, clouds, rainfall and climate : aerosols from biomass burning perturb global and regional climate'.

assistant: **Innovation**

SMOCC's goal is to investigate a novel mechanism, by which atmospheric aerosols may affect climate. Anthropogenic aerosols, especially from biomass burning, increase the numbers of cloud condensation nuclei over the tropics. This reduces cloud droplet size, which prevents raindrop formation at shallower levels in the atmosphere and forces precipitation to farm at much higher elevations through ice processes. This modifies rainfall location and intensity, but also leads to large-scale changes in atmospheric dynamics, which impact climate world-wide, including Europe. Integrating atmospheric chemistry and meteorology, we will characterize the aerosol chemically and physically; identify properties responsible for cloud droplet activation; model the effects of cloud microphysics, and test the models by satellite remote sensing; and model the effects on climate dynamics to predict the impact of the proposed mechanism on climate and hydrology.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Sustainable Seafood Production' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

Bluegrove Welfare Shield tackles an unresolved major issue in aquaculture: fish welfare; by introducing the most advanced salmon welfare monitoring and prediction solution. The system monitors fish behaviour 24/7 gathering data, which are combined with environmental models (e.g. water temp., oxygen & current speed, sunlight effects, weather conditions) and farming data (e.g. fish size & count, feeding area) to detect significant patterns that correlate with welfare issues.Obtained data is presented in a user-friendly dashboard (accessed both locally and remotely) providing live analysis of fish behaviour and appetite, fish welfare tracking, and alerts of potential conditions that could lead to welfare issues. Early detection of welfare issues enables farmers to take preventive actions to avoid an outbreak, and thus reducing mortality rates by 25% and improving fish growth up to 15%. It also provides advice on best practices, and benchmarking against the most productive fish cages.


**Keywords:** Aquaculture,fish welfare,fish behaviour,Hydroacoustic,Artificial Intelligence, Salmon aquaculture
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Does exposure to artificial light at night impacts immunity and microbiome in natural populations of an amphibian?' in the context of a Horizon Europe call.

assistant: **Objectives**

The constant increase of urbanization and human activities worldwide is exposing animals and human to a multitude of stressful stimuli that disrupt physiological functions in organisms. A major source of pollution nowadays, that affect 99% of the european territory and thus almost every organism in Europe, is light pollution (or ALAN, Artificial Light at Night). Recent studies suggest that the immune function could be strongly disrupted by exposure to ALAN, but these results mostly comes from experimental studies conducted in laboratory conditions, and thus not realistic of real conditions of exposure to the light pollution. Considering the current major biodiversity loss crisis, especially in amphibian taxa, it is crucial to know if the ability of wild organisms to mount appropriated immune respones and control infections is affected by this anthropic source of pollution. Within an eco-immunological and One Health framework, this project has thus been designed to characterize for the first time, and totally in natura, the effects of ALAN on immunity, microbiome composition and infectious phenotype of a common nocturnal Vertebrate, the common toad (Bufo bufo). Using 30 wild populations of common toads living on a natural gradient of exposure to ALAN in a french region, this project will characterize:(i) How exposure to ALAN impact toads immune phenotype, using multiple measures to precisely characterize the different immune components that may be differently affected. (ii) How exposure to ALAN impacts toads microbiome composition at the two main interfaces of skin and intestinal mucosa, characterizing bacterial and eukaryotic communities. (iii) If toads infectious phenotype is dependent of ALAN exposure, immune responses and microbiome composition - focussing on pathoge
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Tailoring lattice oxygen and photo-induced polarons to control reaction mechanisms and boost catalytic activity'.

assistant: **Objectives**

Photoelectrochemistry can revolutionise our way of life by harnessing sunlight to produce renewable fuels and chemicals and by helping us preserve the planet for future generations. However, enhancing the efficiency and selectivity of photoelectrochemical (PEC) reactions remains a challenge, especially for the photo-transformation of organic compounds required in industry. The problem stems from the difficulty of characterising the catalytic interface of heterogenous systems under working conditions. This prevents us from elucidating the reaction mechanisms and, so far, has dramatically limited our ability to control reactivity in a similar way to what can be achieved with homogeneous molecular catalysis. A particular challenge of solids is that they are prone to form defects during catalysis. However, how defects and lattice distortions impact the steps of the catalytic cycle remains unknown. Such mechanistic understanding is critical to redesign new materials and boost catalytic efficiencies.PhotoDefect will address this gap in our understanding by applying new methodologies to the study of oxidation reactions at metal oxide photoelectrodes. Our approach is to combine operando mass spectrometry and electrochemistry with optical and X-ray lasers to provide unprecedented insights into the polarised interface. Our strategy is to detect, in situ, the formation of reactive intermediates, defects and catalytic products in order to map out reaction mechanisms and establish ways to control them on demand.We will use cutting-edge methodologies to establish whether defects and photoinduced structural distortions or polarons participate in the steps of the catalytic mechanisms. Most importantly, if successful, our results will reveal new ways to tune the yield and selectivity of
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Multi-wavelength searches of the elusive population of obscured AGN' (MSEPOA) targeting Sixth Framework.

assistant: **Abstract**

We propose to use X-ray data from two pioneering in their kind and complementary multi-wavelength surveys, in order to perform a systematic study of obscured AGN. These leverage substantial investments of space- and ground-based telescope time, yielding a unique dataset to study the obscured Universe. The elusive population of obscured AGN most likely dominates the population of accreting super massive black holes, however, it remains mostly undetected.The impact of multi-wavelength observations for the study of AGN is crucial and the only way to obtain accurate demographics of obscured AGN at high red shift. If our findings will show substantial and widespread obscuration, this will have important implications for the cosmic accretion history of black holes. The pro posed collaboration will promote the professional reintegration of the proposed researcher and will help expanding the activities of the X-ray group of the Institute of Astronomy and Astrophysics of the National Observatory of Athens, by blending the fields of expertise of the researchers involved and by combining the unique datasets to which each party has access.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Maternal Interventions to Reduce Asthma: Targeting Novel Endotypes in Early Life' to be submitted under Horizon Europe.

assistant: **Abstract**

Asthma is a common childhood disorder with a heterogeneous presentation, representing multiple disease endotypes with distinct underlying mechanisms. Understanding these mechanisms in early life can enable personalised asthma prevention, addressing a significant unmet medical need, but no asthma/wheeze endotypes have been identified in young children that can be targeted. My preliminary findings from untargeted plasma metabolomics profiling in the COPSAC2010 and VDAART birth cohorts showed that maternal oxylipins, particularly undetectable 12-HETE, are associated with a distinct asthma endotype. Further, preliminary data showed a primary preventive effect of n-3 long-chain polyunsaturated fatty acid (n-3 LCPUFA) supplementation in pregnancy only among mothers with detectable 12-HETE levels, highlighting a potential for personalised prevention. The MIRA project aims to uncover the mechanisms behind this novel oxylipin-associated childhood asthma endotype and develop tailored prevention strategies. This involves measuring targeted oxylipin profiles and investigating the determinants of maternal oxylipins during pregnancy and their impacts on infant alveolar macrophages (AMs), airway microbiome, longitudinal metabolome and proteome, and asthma outcomes in COPSAC2010 and VDAART. The project will also explore personalised strategies involving prenatal n-3 LCPUFA exposure. Mechanistic studies using wild-type and ALOX15-/- transgenic mice will evaluate the effects and uncover the mechanism. A key innovation of this project is the development of dry blood spot (DBS) screening tool for pregnant women, enabling early risk stratification and personalised intervention. The project will engage in patenting, technology transfer, intellectual property protection, and prototype validat
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Plasmonic nanopore technologies for automatic manipulation and Raman spectroscopic sequencing of single proteins' (RamanProSeq).

assistant: **Innovation**

The human proteome offers unprecedented insights into health, diseases and treatment. The current protein detection techniques are either expensive, insensitive, complex or introduce biases. Meanwhile, no amplification methods for proteins exist, which complicates their detection and leads to a serious lag of proteomics behind genomics and transcriptomics, hampering not only mechanistic studies but also clinical applications. The RamanProSeq project aims to develop a label-free optical single-molecule protein sequencing technology capable of reading protein primary sequence at single-amino-acid resolution with high accuracy (>99.9%). The proposed technology will revolutionise the field of proteomics towards personalized medicine and early diagnosis of diseases. The project will be based on the partners' approaches: ultrafast Raman spectroscopy with 1 microsecond time resolution and plasmonic nanopore-enhanced Raman sensors  that have demonstrated single-molecule identification of 20 proteogenic amino acids, their post-translational modifications and discrimination of single amino acid residues within single peptides. Such achievement has addressed the long-standing challenge of current single-molecule technologies that cannot detect all 20 proteinogenic amino acids. Based on these approaches, the RamanProSeq project will integrate solid-state nanopores with a high-speed Raman detection system, an automated control system, computer simulations, and advanced Raman-based bioinformatics. The output of the project will be a novel nanopore-based device that will be used to sequence individual proteins at low concentrations and with high accuracy. The project will enable low cost, high resolution and high throughput in single-protein sequencing for a broad range of application
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Brain-inspired Computing for Next Generation Generative Artificial Intelligence'.

assistant: **Concept**

As generative AI and large language models drive unprecedented demand for computational resources, traditional GPU-based architectures are reaching their fundamental limits, creating a mounting crisis in energy consumption, cost, and accessibility. Inspired by the human brain's remarkable ability to perform complex computations with minimal energy consumption, we have developed revolutionary AI hardware architecture that redefines the boundaries of computational efficiency. Our SpiNNaker2 chip and SpiNNcloud system translate millions of years of biological evolution into cutting-edge technology, delivering brain-like performance while dramatically reducing energy requirements. Building on our validated SpiNNaker2 technology, we are now introducing SpiNNext—our next-generation chip specifically designed for the emerging demands of modern generative AI. SpiNNext architecture directly addresses the mismatch between increasingly sparse, selective computation patterns in advanced algorithms and traditional dense processing architectures by implementing native hardware support for dynamic sparsity. SpiNNext will enable new possibilities in AI development while maintaining European technological sovereignty. The remarkable energy efficiency of our technology translates directly to significant environmental sustainability through significant reductions in AI-related carbon footprint.


**Keywords:** Multi-paradigm AI Hardware, Foundational AI Models, Large Language Models (LLMs), Brain-inspired Architecture, Neuromorphic Computing, SpiNNaker Technology
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Convergent and Efficient Synthesis of Novel Heteroaromatics' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

Cycloaddition reactions are extremely potent methods to form complex heterocycles. However, [3+2]-cycloadditions across alkynes are generally ineffective for the formation of 1,3-azoles which are key constituents of natural products, pharmaceuticals and materials. This project aims to establish a convergent and readily applicable gold-catalysed formal [3+2]-cycloaddition strategy to prepare diverse highly-substituted 1,3-azoles and related heteroaromatic structures. Reaction discovery and optimization will be followed by a detailed study of the substrate scope which will include the preparation of bioactive materials to demonstrate the efficacy of the proposed methodology to the synthetic community.The second major strand of the project will exploit the ability of this methodology to provide expedient access to functional materials, in the form of chiral aminooxazoles as the basis of organocatalyst systems. Transfer of the fellow’s prior expertise and knowledge of system design and reaction application in organocatalysis will be central to the development, study and application of this potentially privileged scaffold at the core of a range of organocatalyst families. The modular and convergent method of the oxazole synthesis will facilitate both major and fine tuning of the catalysts function in single point, dual point and triple point activation, across nucleophilic catalysis, H-bond activation, and secondary amine catalysis for iminium and enamine based processes.As well as the research impact and added value to the project from knowledge transfer, outreach activities across several layers of the population will be performed. An accessible resource will be prepared for scientists; general public knowledge and appreciation of chemistry will be enhanced, and the enthus
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Social Capital: Interdisciplinary Perspectives' (1998-2002).

assistant: **Concept**

The recent introduction of the idea of 'social capital ' in the social sciences has had a decisive impact both in the methodology of social research and in important areas of substantive research on the political and economic conditions of modern society, Europe in particular. Its very conceptualisation has stimulated important research projects and has shown the way in which to link different issues and different disciplines. Because of its fortune, however, the idea has perhaps been over-stretched both as a way of explaining complex social macro-processes and as an all-comprehensive concept. There is a growing feeling in the scientific community that some methodological and conceptual rigour is needed to maintain the explanatory potential of 'social capital' research. This implies both looking again at the micro-foundations of the theory of social capital and establishing ways of comparing research done within and across disciplines.The conference is meant to provide a context for these two operations. Its main objectives are: a) encourage conceptual clarification; b) set up exchange between different approaches and disciplinary perspectives; c) verify the extent of the impact of social capital research on important themes in the social sciences.ftp://ftp.cordis.lu/pub/improving/docs/HPCF-2000-00222-1.pdf
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Molecular Networks of Dopaminergic Neurons in Chordates' under Seventh Framework.

assistant: **Concept**

Background. Parkinson Disease is the second most common progressive neurodegenerative disorder. The selective degeneration of subsets of midbrain dopaminergic neurons is believed to be the primary cause for disruption of the ability to control movements. Objective. We propose to apply a highly interdisciplinary approach to construct complex networks consisting of protein coding genes, non-protein-coding genes and cis-regulatory elements within dopaminergic neurons in the brain across three chordate organisms (Mouse, Zebrafish and Ciona) to identify and compare gene regulatory networks in these neurons. This will be achieved by: • Expression profiling of genes on single dopaminergic neurons via laser microdissection and transgenic lines in Mouse, Ciona and Zebrafish • HT-Sequencing of microCAGE assays on dopaminergic neurons, providing TSS usage and transcript discovery • Microscopy HTS of cis-regulatory elements • siRNA and morpholino network perturbation experiments • Innovative systems biology approaches to decipher and define molecular networks Data generated by microCAGE and microarray will define a set of key genes in dopaminergic neurons, in which cis-regulatory elements will be predicted and screened utilizing HTS in zebrafish. The data will aid network reconstruction, which will be validated by perturbation experiments. This project relies also on the availability of data produced through the many existing collaborations among consortium partners such as FP6 funded TRANSCODE project as well as the international Fantom3 consortium. Potential impact: The prevalence of PD in Europe today is ~2 million people. Within the next 50 years, the number is expected to rise to 5 million. Thus, the burden placed by dementia on the working-age population will rise dramaticall