RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Inequalities on Function Spaces and Properties of Integral Operators with Applications' (IFIOP).

assistant: **Innovation**

Our investigation is in the area of functional analysis and concerns boundedness and compactness properties of mappings between function spaces, estimates and asymptotic behaviour of characteristic numbers of integral operators and also embeddings between function spaces. The expected results may be useful for solutions of a number of actual problems in neighbouring mathematical areas such as the theory of differential and integral equations, interpolation theory, harmonic analysis, probability theory, etc.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fifth Framework proposal for the project 'European sea floor observatory network'.

assistant: **Objectives**

The aim is a network of sea floor observatories around the European Ocean Margin from the Arctic Ocean to the Black Sea for strategic long term monitoring as part of a GMES with capability in geophysics, geotechnics, chemistry, biochemistry oceanography, biology and fisheries. Long-term data collection & alarm capability in the event of hazards (eg earthquakes) will be considered. An Atlas of European Margin assets & hazards, model products from existing observatories & a list of potential participants will be produced as a basis for forward planning. Data requirements will be reviewed together with existing capability. Future observatory designs and data management networks including data acquisition, via telemetry, scientific cables and oil industry cables will be considered in a series of workshops. The project outcome will be costed proposals for phased implementation of a sea floor GMES system in key regions around Europe.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Positioning and Characterization of Ligand Stabilized Metal Clusters on Surfaces and In Confinements' (1994-1998) targeting Fourth Framework.

assistant: **Abstract**

The goal of this project is to synthesize ligand stabilized metal clusters of quantum dot size and position such dots on surfaces, and in confined spaces in a regularly spaced manner. Nano-sized metal clusters can be made of any metals and the thickness of the protecting layer of ligand can be tailored by choosing suitable ligands. This forms the base for the ordered positioning of the clusters in one, two and or dimensions. By the right spacer and size of the quantum dots, single electron tunnelling can be achieved on surfaces, in channels and cavities. This can lead to true future nano electronics. The task of the applying teams is to combine expertise in inorganic chemistry, structural chemistry, solution chemistry, electron microscopy and solid state physics. This will permit a concerted approach to understanding and developing of new material. Large groups and institutes in Japan and the US are presently devoting their efforts towards new nanoelectronics, but the suggested constellation of research groups constitutes and solid state physics. This will permit a concerted approach to understanding and developing of new materials. Large groups and institutes in Japan and the US are presently devoting their efforts towards new nano electronics, but the suggested constellation of research groups constitutes a unique new combinations of ideas for synthesis, positioning and characterization of structure and properties. The scientific research in this project involves six academic institutions from four countries and all are selected for their complementary expertise" in chemistry or physics. The project has been designed to open the doors between physics and chemistry, thereby exchanging ideas, scientist and skills. There will be at least one post doc associate working on
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'SUper-Resolution Photonics for Advanced Storage Systems' (SURPASS) targeting Seventh Framework.

assistant: **Abstract**

The purpose of the restructured SURPASS project is to develop key technologies to achieve super-resolution beyond the diffraction limit in air at visible wavelength. The application fields covered by the project are optical data storage, wafer inspection, maskless optical lithography and confocal microscopy.The first super-resolution technology is based on so-called super-RENS materials (Super-Resolution Enhanced Near-Field Systems). These materials, such as the semiconductor InSb, undergo a local modification of their refractive index properties above a certain power threshold of a focused laser spot. As a consequence they produce a reduction of the effective size of the laser spot. Super-RENS materials are developed mainly for optical ROM discs to allow the readout of recorded marks smaller than the resolution limit of the optical readout system. The maximum capacity of single-level Super-RENS discs will be studied theoretically and experimentally. In parallel, semi-transparent Super-RENS levels will be developed and the industrial potential of this technology for multi-level discs will be evaluated. The purpose is to propose a technological solution for the extension of the Blu-Ray format from 25 GB to 75-100 GB for high-definition video content distribution.The second super-resolution technology is based on micro-solid immersion lenses (µ-SILs) which enable to reduce a focused laser spot by a factor equal to the refractive index of the µ-SIL. A low-cost manufacturing process will be developed on 200 mm silicon wafers. The resolution of µ-SIL should be further enhanced by using engineered polarization, high index material, plasmonic nanostructures at focus or functionalization with a Super-RENS layer. The performances of high-resolution optical heads including a µ-SI
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Biomedical Image Quantification by a Scalable and Open Cloud Solution' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

BiQ-Cloud (Biomedical Image Quantification Cloud) is a groundbreaking cloud-based platform designed to revolutionize biomedical research by providing scalable, cost-effective, and cutting-edge image analysis tools. Current solutions are often either costly and outdated or require specialized IT skills, thereby limiting access for many users, including researchers, small and mid-sized companies, as well as large-scale organizations. BiQ-Cloud overcomes these barriers by offering a flexible platform that allows users to access the latest image analysis algorithms without purchasing expensive licenses or hardware. By leveraging cloud computing, our system provides on-demand access to powerful processing capabilities and state-of-the-art tools on a pay-per-use basis. Clients can securely upload data, which is processed by dynamically deployed Docker containers, ensuring continually up-to-date analysis capabilities with no complex installations. Our platform supports the rapid integration of new algorithms through an open API, thus fostering continuous innovation. It also leverages client-provided data to train AI models, further enhancing speed and accuracy over time. By democratizing access to advanced biomedical image analysis, BiQ-Cloud accelerates discoveries and improves drug development reliability.The ERC PoC grant will enable us to advance BiQ-Cloud from a functional prototype into a market-ready product, unlocking its potential to transform biomedical research and become the leading platform for researchers and industry professionals worldwide.


**Keywords:** Cloud computing, Bioimaging, Pay-per-use
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'ODYSSEUS' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

The aim of the Odysseus project is to develop an Open Dynamic System (ODYS) enabling the 'holistic energy management' of the dynamics of energy supply, demand and storage in urban areas, on top of an open integration platform supporting the integration scenario's for designated urban areas exemplified in the cities of Rome and Manchester. While in Manchester project results will be validated on a mature energy efficiency environment, on Rome it is in the early stages of dealing with energy efficiency in public building. So comparisons among each scenario will enrich conclusions on project results.The concept of holistic energy management covers the monitoring of energy operation in a certain area according to 1) dynamic energy profile information for all relevant 'energy nodes' and 2) the actual conditions and behaviour of all these nodes. Based on integral monitoring of planning and actual information problems can be spot (like deviations) and recommendations for resolution and in general optimization including commercial negotiation processes between the stakeholders (long term decision support). The later especially for real-time but also more tactical or even strategic adaptations (adding or changing nodes, changing connection, profiles, ...).The Open Integration Platform will capture all energy node information required in a dynamic Energy Profile Card" structured according to a proposed full taxonomy of energy node types and their associated properties and interrelationships. All instance data according to these information structures and these information structures themselves will be stored in an open standards-based and open source-based spatial database accessible via standard interfaces to keep the system flexible, interoperable, adaptable and extensible.Odys
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Development of high-field DNP-enhanced MAS NMR techniques for structure determination of viral capsids'.

assistant: **Innovation**

The atomic-level characterization of large viral particles is one of the greatest challenges of modern structural biology, as well as a fundamental step for the design of effective antiviral treatments. In viruses, the viral genome (double- or single-stranded RNA or DNA) is associated to multiple copies of a capsid protein, forming predominantly icosahedral or helical architectures. These complex superstructures are often studied by X-ray crystallography and electron microscopy (EM). However, only information at low resolution is usually available from EM, and extended and flexible architectures do not provide single crystals amenable to diffraction studies. Over the last years, solid-state NMR (ssNMR) has developed into a powerful structural tool for studying structure and dynamics of solid biological samples at atomic resolution and is now uniquely positioned to complement diffraction-based techniques for the characterization of large functional assemblies. However, proteins of large size or that are available in limited amounts are still inaccessible to site-specific NMR studies. Exploiting a unique equipment available in the host institution, the project aims to remove the current bottlenecks and develop improved dynamic nuclear polarization (DNP)-enhanced ssNMR methodology to push forward the limits of applicability of this technique to macromolecular assemblies, opening new avenues to ssNMR in structural biology. Innovative experimental approaches will be developed to overcome the resolution barriers that currently limit the application of high-field DNP, and new spectroscopic tools will be introduced to allow the structure determination of biomolecules under DNP conditions. The effectiveness and versatility of the newly developed methods will be tested on two vir
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Tissue regeneration and aging: the decisive quiescent stem-cell state' (STEM-AGING).

assistant: **Concept**

The basic mechanisms of stem cell malfunction during aging are poorly understood even though they underlie the regenerative decline of most organs and tissues as we age. Based on our recent contributions (Nature 2014, Nature 2016), the fields of tissue regeneration and aging converge on the key role of the quiescent state, the preferred state of stem cells in low turnover tissues such as skeletal muscle. Our unifying hypothesis is that stem-cell quiescence maintenance, which requires active proteostasis (protein homeostasis), lies at the basis of stemness, and that its substitution by a senescence state in aging impairs regeneration. How these variables connect to drive stem cell aging is not known. Crucial experimental systems in this proposal are sensitive reporter mice for proteostasis, senescence and quiescence/fate in aging muscle stem cells. The project is divided as follows: Objective 1. Proteostasis and stem cell quiescence maintenance: tracing proteostasis in quiescent stem cells from autophagy and chaperone-mediated autophagy (CMA) reporter mice during aging / impact of autophagy/CMA loss on quiescence and regeneration / molecular regulators of proteostasis. Objective 2. Proteostasis and quiescent stem cell heterogeneity and fate: asymmetric segregation of proteotoxic waste as an instructor of stem cell heterogeneity and regenerative fate. Objective 3. The quiescence-to-senescence-switch in aging muscle stem cells: tracing and isolating senescent stem cells in senescence-cell reporter mice during aging / impact of senescent cell ablation on regenerating aged muscle. Objective 4. Circadian regulation in the quiescent stem-cell state: impact of aging on circadian rhythms and consequences for quiescence maintenance and regeneration. We expect that completion of t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Organometallic Reactions in Carbohydrate Chemistry' (2007-2013).

assistant: **Innovation**

The aim of this project is to apply some state of the art transition metal catalysed reactions to carbohydrate systems. We plan to investigate the possibilities of using transition metals to catalyse C-C fond forming cyclisations and C-N bond forming cyclisation and cross-coupling reactions. In carbocyclisation reactions, we will be focussing on ene-yne systems, which will be synthesised from carbohydrate starting materials. Electrophilic transition metal complexes such as gold complexes can induce cyclisation of an alkene onto an activated alkyne. Alternatively, debenzylative etherification may be favoured. Ruthenium complexes can carry out one-pot oxidation-reductive-amination to form secondary amines from primary amines and alcohols. We plan to apply this reaction to the synthesis of amine-linked disaccharides, and also to cyclisation reactions where a carbohydrate-derived diol can cyclise with a primary amine, giving an N-substituted iminosugar or azasugar. A combination approach where alkene and alkyne functionalities are introduced to a molecule by the amine coupling reaction followed by a carbocyclisation will be investigated. The polyhydroxylated products of these reactions will be new or known glycomimetics. The new compounds will be tested for their biological activity by our collaborators.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Novel assessment of bridge retrofitting measures through Interface Efficiency Indices (InterFeis) using a Guided Wave-based monitoring method'.

assistant: **Objectives**

Modernisation of our deficient transportation networks and in particular bridges is a pressing requirement imposed by the growing EU economy, vital to societal coherence and safety. Frequent retrofitting solutions include the use of versatile Fiber Reinforced Polymers systems (FRPs), which have been proven to enhance the capacity and deflections of bridges. Nevertheless, it is surprising that only a few, if any, research results are available with regard to the efficiency and appropriateness of FRP systems used on bridge retrofitting schemes, whilst international design guidelines neglect the level of integration of the measures with the existing bridge components. In practice, and especially in bridge decks were deterioration is expected, there is a number of limitations that reduce the level of integration of the FRP system with the bridge. This gave the BriFace project a strong motivation to utilise Structural Health Monitoring (SHM) techniques to assess the efficiency of the strengthening measure and quantify those, for the first time in the international literature, with the Interface Efficiency Indices (InterFeis), by measuring reliably the interface deflections and strains and by taking into account the failure modes and the limit stress states of bridge components. The novel objectives of BriFace are: 1) To define the Interface Efficiency Indices, 2) To utilize an expedient, long-distant inspection method of guided waves for the first time in bridge inspection, 3) To increase the interface efficiency by chemical means potentially by using nanoparticles and 4) To use InterFeis as a reliable indicator toward the quantification of the redundancy of the retrofitted bridge, as a means to assess its capacity and thus its resilience. The research outcomes will also ben
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Multi-Use in European Seas' under Horizon 2020.

assistant: **Concept**

The Multi-Use in European Seas (MUSES) project will review existing planning and consenting processes against international quality standards for MSP and compliance with EU Directives used to facilitate marine and coastal development in the EU marine area to ensure that they are robust, efficient and facilitate sustainable multi use of marine resources. The project will build knowledge of the appropriate techniques to minimize barriers, impacts and risks, whilst maximising local benefits, reducing gaps in knowledge to deliver efficiencies through integrated planning, consenting processes and other techniques.  MUSES Project - 3 main pillars: 1. Regional overviews which take into account EU sea basins (Baltic Sea, North Sea, Mediterranean Sea, Black Sea and Eastern Atlantic) will be based on an analytical framework to facilitate adoption of a common approach across the sea basins.  The progress in implementation of the concept of Multi-Uses in European Sea Basins will be assessed and key obstacles and drivers identified.2. A comprehensive set of case studies of real and/or potential multi-use will be conducted and analysed to provide a complete spectrum of advantages in combining different uses of the sea. The case studies will create local stakeholder platforms to identify multi-use potentiality, opportunities and limitations. 3. Development of an Action Plan to address the challenges and opportunities for the development of Multi-Uses of oceans identified in the regional overviews and case studies. Provide recommendations for future action, taking into account national, regional and sea basin dimensions.The project will build on work undertaken in other studies including Mermaid, TROPOS, H2Ocean and SUBMARINER.  MUSES project partners have direct links with related for