RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Chemical building blocks from versatile MSW biorefinery' (PERCAL).

assistant: **Innovation**

PERCAL will exploit Municipal Solid Waste (MSW) as feedstock to develop intermediate chemical products at high yield and low impurity level with huge industrial interest. These will be complementary to the bioethanol (current PERSEO technology), to achieve a cascade valorisation of the MSW components, i.e.:• Lactic acid (LA) to produce: 1) Eco-friendly ethyl lactate solvents by reactive distillation from lactic acid & bio-ethanol to be used in cleaning products and inks and 2) hot-melt adhesives for cardboard and other non-food applications in combination with maleic anhydride by reactive extrusion.• Succinic acid (SA) as an intermediate building blocks to production of polyols for the polyurethane industry.• Biosurfactants by chemical and/or microbiological modification of protein and lipid fraction from remaining fraction of MSW fermentation.IIn order to minimize the MSW heterogeneous composition (due to seasonal and origin variability driven by local economic, social and climate conditions) limitations as a fermentation feedstock, four main innovations will be proposed: i) New enzymatic cocktails to maximize hydrolysis of fermentable organic matter with low inhibitors production, ii) the use of high yield, specific and robust strains for each selected acid, iii) the extraction of fermentation by-products acting as inhibitors to succinic acid production via novel membrane electrolysis employing an integrated continuous fermentation coupled with simultaneous organic acid removal in comparison with SA sequential fermentation followed by its separation using an electrodialysis-based and iv) optimize simultaneous saccharification and fermentation for lactic acid production followed by a downstream separation process based on membrane electrodialysis. To maximize the yield
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'European Space Robot Control Operating System'.

assistant: **Concept**

The ESROCOS activity is devoted to the design of a Robot Control Operating Software (RCOS) that can provide adequate features and performance with space-grade Reliability, Availability, Maintainability and Safety (RAMS) properties. The goal of the ESROCOS proposal is to provide an open source framework which can assist in the generation of flight software for space robots. By providing an open standard which can be used by research labs and industry, it is expected that the elevation of TRL levels can be made more efficient, and vendor lock-in through proprietary environments can be reduced. Current state-of-the-art robotic frameworks are already addressing some of these key aspects, but mostly fail to deliver the degree of quality expected in the space environment. Terrestrial RCOS developed by industrial robot companies (e.g. VxWorks, PikeOS) are not usable for space robotics because their Intellectual Property Rights (IPR) enforce the vendor’s dependency on space development. Other open-source frameworks do not have sufficient RAMS properties for its use in space missions. The ESROCOS objectives are to: 1. Develop a Space-oriented RCOS including space-grade RAMS attributes, formal verification and qualification of industrial drivers.2. Integrate advanced modelling technologies, separating the model from the platform3. Focus on the space robotics community, with requirements coming from actors leading robotics missions 4. Allow integration of complex robotics applications by including the Time and Space partitioning approach5. Avoid vendor-lock in situations by delivering an open-source solution 6. Leverage on existing assets, such as already existing frameworks properly extended, mature toolsets  and libraries)7. Ease the development of robotics systems by providing
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'A Clostridal Biology Network to Facilitate European-wide Medical Countermeasures and Commercial Exploitation' (CLOSTNET) under Seventh Framework.

assistant: **Objectives**

There is an urgent need to better understand the basic biology of Clostridium as a prerequisite for both countering the diseases they cause (C.difficile, C.perfringens and C.botulinum), and exploiting their beneficial properties in industry (biofuels by C.acetobutylicum) and medicine (cancer therapy by C.sporogenes). Attainment of this goal is being impeded because: (i) European research efforts are fragmented; (ii) there is no coherence between researchers working on pathogenic species and industrially important strains; (iii) there is a demonstrable (SCF-CT-2005-029958) lack of trained young clostridial researchers; (iv) there is inadequate networking between industry and academia, and; (v) effective exploitation of the amassed clostridial genome data has been precluded by a woeful inadequacy in procedures for gene inactivation. Removal of these impediments cannot be achieved at a national level, but requires the creation of a transnational network of multi-disciplinary experts,active in different scientific sectors. The technical hurdle to progress has now been solved by partner 1, who has developed a highly effective andreproducible gene knock-out system. The remaining hurdles will be overcome by bringing together a multidisciplinary team of research expertise from 7 different EU states drawn from Academia (5), Government (3) and different sectors of Industry (3). A principal focus will be to address the deficiency in critical mass by providing young researchers with world class, state-of-the-art, multidisciplinary training in leading scientific and biotechnological skills that have relevance to medical countermeasures against pathogens and the exploitation of non-pathogens in industrial processes and disease intervention. These measures will establish Europe as a ‘
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'European System For Local Authorities networking Domains' goes beyond current state-of-the-art under Fifth Framework.

assistant: **Innovation**

Local and Regional governments can be a powerful booster of the Information Society. But they lack consistency to apply ICT, in particular because they are too much on their own and do not perceive sufficiently the benefits of acting as part of a system. This situation can change by launching mainstream ICT-driven projects as catalysts for innovation and for reengineering of their working methods.Such projects must solve a key issue: provide solutions that allow data retrieval and information exchange between Local and Regional governments without forcing radical changes to their actual information systems, or requiring complex organisational models, or costly investments in externally driven systems. EUSlanD addresses all these problems by providing a creative model, through co-operation between civil servants and experts from Local and Regional governments, aiming at a web information retrieval and networking system to be used by thematic networks. The searching system is based on information abstracts leading to the relevant data stored in the databases managed by EUSlanD providers, complemented by telematic/multimedia service packages to gradually increase the exchange of knowledge between these civil servants and experts, in a European environment.Objectives:EUSlanD will create a flexible and open system for the use of Local and Regional governments, based on a shared knowledge management model. The research system will enable deployment and integration of existing information at local and regional government level, through intelligent supports favouring their provision, semantic classification and exchange.To demonstrate and prepare the exploitation of the system, making use of actual transnational experiences in need of ICT tools to increment the number and range
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'DDD60 - High Quality VR for FilmTV industry professionals' (DDD60).

assistant: **Innovation**

DDD60High-Quality VR for Film & TV industry professionalsDDD60 will introduce cutting edge video compression and delivery technology to deliver high-quality VR content to Film and TV professionals. DDD60 will show immersive content in some of the leading Film & TV markets worldwide.Driven by the games industry, VR devices are currently flooding the market. Film and TV are picking up VR as well: Content is produced in all areas of film, led by documentaries and journalism, VR is revolutionizing the industry. At a much slower pace, the creators of fictional content are experimenting with the new technology as well.While the creatives are developing the craft of creating VR films, one major obstacle for the distribution of VR content remains: The files are huge. And since the internet infrastructure does not grow as quickly as the size of VR files, content distributors, in an effort to minimize file size, have to greatly reduce the quality of the content they show online – if they can show it at all. In addition, storing big files is expensive, especially for the budget of creative industry SMEs.DDD60 will greatly enhance the quality of VR content delivering online: By improving compression technology and transcoding mechanisms, the size of the files and the amount of information to be delivered through the internet will be reduced greatly, giving distributors the chance to deliver higher quality. And by improving storage and delivery workflows the efficiency and the cost for delivery will be reduced to an extent that will make the online screenings of VR content a viable business for European SMEs.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'AGLARIS: The First Fully-automated Bioreactor for Large Scale Human Stem Cell Production through an Iterative Process.' in the context of a Horizon 2020 call.

assistant: **Objectives**

In order to meet the expanding market for human stem cells (HSCs) in cell therapy, automated, cost-effective, large-scale manufacturing processes are required. AGLARIS Project is centered in the market launch of the patented AGLARIS BIOREACTOR for large-scale HSCs production, which perfectly meets the requirements for cell-based therapeutic products. Current bioreactors for HSCs producers consist in attempts to adapt bioreactors derived from traditional bioprocesses, but its use has not been widespread as they are not optimized for HSCs production. The automation level of bioreactors is limited to an initial quantity of 20M cells. As the cell sample from biopsies contains 0.5-1M cells, a previous manual cultivation is always required to reach the minimum quantity. This step affects cell quality. AGLARIS operates with the quantity of cells coming directly from biopsy, completely eliminating the manual pre-cultivation requirement. Moreover, current Bioreactors are limited to 300M cells per cell batch. The common are based on hollow-fibers as the substrate in which cells are anchored for growing. Once they reach its maximum capacity, cells need to be detached by using chemical and enzymatic reagents. AGLARIS operates in an iterative manner reaching 5000M cells without dividing the cultivation process in several batches. It is based on microcarriers which allows cell detachment by a simply small variation of temperature, avoiding adverse side effects. Additionally, for a complete disease management, the production of 600M cells on average is required. When produced manually, the cultivation of 600M cells can reach 9.347€, and by using hollow-fiber Bioreactors 15.643€. AGLARIS optimized culture process produces cell yields with the correct quality while using minimal amounts
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Exploring the outer solar system beyond Neptune using stellar occultations'.

assistant: **Objectives**

The solar system beyond Neptune’s contains largely unaltered material from the primordial circum-solar disk. It also kept the memory of the early planetary migrations, and thus contains essential information on the origin and evolution of our planetary system.Here I propose to study the Trans-Neptunian Objects (TNOs) using the stellar occultation technique. It consists in observing the passage of remote TNOs in front of those “Lucky Stars”, that reveal shapes, atmosphere and rings of bodies from sub-km to thousand-km in size. Very few teams in the world master this method. The European-led network that I coordinate is now leader in predictions, instrumentation, observations and analysis related to stellar occultations, with innovative approaches and unprecedented results.In the last decade, our group led the field by discovering rings around the asteroid-like object Chariklo, detecting sub-km TNOs and drastic variations of Pluto’s atmospheric pressure. Based on those noteworthy discoveries and unique skills of ours, I will coordinate the following work packages:(1) Rings around small bodies - Understand the newly found Chariklo’s rings, tackle the theory of rings’ origins and evolutions around small bodies, discover new ring systems around other bodies. (2) Very small, sub-km TNOs and Oort Cloud objects - Constrain the collisional history of our early outer solar system, and possibly detect Oort Cloud objects.(3) Pluto’s atmosphere – Explore Pluto’s atmosphere and its atypical seasonal cycle, search for atmospheres around other TNOs.(4) Explore specific, large TNOs – Provide their sizes, shapes, albedos and densities.These programs are timely in view of NASA/New Horizons Pluto flyby in July 2015, and the ESA/GAIA mission expected to provide a greatly improved astrometri
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Complex Patterns for Strongly Interacting Dynamical Systems' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

This project focuses on nontrivial solutions of systems of differential equations characterized by strongly nonlinear interactions. We are interested in the effect of the nonlinearities on the emergence of non trivial self-organized structures. Such patterns correspond to selected solutions of the differential system possessing special symmetries or shadowing particular shapes. We want to understand, from themathematical point of view, what are the main mechanisms involved in the aggregation process in terms of the global variational structure of the problem. Following this common thread, we deal with both with the classical N-body problem of Celestial Mechanics, where interactions feature attractive singularities, and competition-diffusion systems, where pattern formation is driven by strongly repulsive forces. Moreprecisely, we are interested in periodic and bounded solutions, parabolic trajectories with the final intent to build complex motions and possibly obtain the symbolic dynamics for the general N–body problem. On the other hand, we deal with elliptic, parabolic and hyperbolic systems of differential equations with strongly competing interaction terms, modeling both the dynamics of competing populations (Lotka-Volterra systems) and other interesting physical phenomena, among which the phase segregation of solitary waves of Gross-Pitaevskii systems arising in the study of multicomponent Bose-Einstein condensates. In particular, we will study existence, multiplicity and asymptotic expansions of solutions when the competition parameter tends to infinity. We shall be concerned with optimal partition problemsrelated to linear and nonlinear eigenvalues
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Regulation of hox genes in vertebrate development and evolution', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

The principal aim of this project is to determine factors that regulate the establishment of the spatially restricted pattern of expression of Hox genes in the developing vertebrate nervous system. Hox genes are true homologues of the homeotic genes first identified in Drosophila and have a central role in axial patterning in all metazoans. Spatial enhancers will be characterised in transgenic mice using a lacZ reporter gene. Deletion and sequence analysis will determine the minimal elements required for the spatial expression of the gene under study, and this will allow us to search for candidate factors that are upstream in the regulatory cascade that leads to pattern formation in the brain. Comparison of the enhancer with similar elements from other Hox genes expressed in overlapping patterns (paralogues) and with homologous genes from other vertebrates (chick and puffer-fish) will help to determine how far these upstream regulatory networks have been conserved in evolution.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Thermal-hydraulics of Innovative Nuclear Systems', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

For the long-term development of nuclear power, innovative nuclear systems such as Gen-IV reactors and transmutation systems need to be developed for meeting future energy challenges. Thermal-hydraulics is recognized as a key scientific subject in the development of innovative reactor systems. This project is devoted to important crosscutting thermal-hydraulic issues encountered in various innovative nuclear systems, such as advanced reactor core thermal-hydraulics, single phase mixed convection and turbulence, specific multiphase flow, and code coupling and qualification. The main objectives of the project are: • Generation of a data base for the development and validation of new models and codes describing the selected crosscutting thermal-hydraulic phenomena. This data base contains both experimental data and data from direct numerical simulations (DNS). • Development of new physical models and modeling approaches for more accurate description of the crosscutting thermal-hydraulic phenomena such as heat transfer and flow mixing, turbulent flow modeling for a wide range of Prandtl numbers, and modeling of flows under strong influence of buoyancy. • Improvement of the numerical engineering tools and establishment of a numerical platform for the design analysis of the innovative nuclear systems. This platform contains numerical codes of various classes of spatial scales, i.e. system analysis, sub-channel analysis and CFD codes, their coupling and the guidelines for their applications. The project will achieve optimum usage of available European resources in experimental facilities, numerical tools and expertise. It will establish a new common platform of research results and research infrastructure. The main outcomes of the project will be a synergized infrastructure fo