RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'From Timbre Perception to the Creative Exploration of Musical Instrument Sound Morphing' (MORPH), addressing dissemination and exploitation.

assistant: **Impact**

Sound morphing has the potential to provide critical new insight into our understanding of timbre perception, and to deliver innovative virtual hybrid musical instruments for the creative exploration of the sonic gap which exists between traditional musical instrument sounds. Timbre, a highly complex perceptual phenomenon traditionally associated with musical instruments, is considered one of the last frontiers of auditory science. Sound morphing holds enormous promise for the investigation of timbre perception because it can gradually blur the categorical distinction between sounds by blending their sensory attributes. In this groundbreaking multidisciplinary project that fuses signal processing, experimental psychology, and music technology, I propose to use sound morphing to create continuous timbre spaces by filling the gaps between traditional musical instruments and therefore breaking the categorical perception of musical instrument timbre by the auditory illusion of hybrid musical instruments. This radically novel approach will integrate a touch user interface to enable the creative exploration of sound morphing with original virtual hybrid musical instruments that push the creative boundaries of musical expression by moving beyond the physical limitations of acoustic musical instruments and the traditional digital musical instruments that rely on them. The impact of this project will be felt across three prominent, complementary research domains, namely: signal processing; timbre perception; and musical interaction. First, this project will advance music signal processing by developing new modeling techniques specifically tailored for musical instrument sounds. Second, it will provide powerful analysis tools to further our understanding of musical timbre percept
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Spectrum Sharing Systems for Improving Spectral Efficiency' (S3ISE).

assistant: **Innovation**

In this project an analytical cross layer framework is developed for optimal radio resource modelling and allocation for multi secondary user spectrum sharing systems. The proposed analytical framework is able to model the impact of the system and service parameters in their corresponding time scales and level of accuracies on the system performance. In particular, one of the objectives of this project an objective is to integrate spectrum sensing into other upper layer functionalities such as power and rate control, and resource scheduling. This improves the spectrum sharing system performance through exploiting inherent dynamics in a spectrum sharing environment in their corresponding time scales. Fundamental system scalability aspects are also investigated in this project through considering multi-user secondary network. Based on the developed analytical framework, the next step is to develop efficient schemes and implement such optimal radio resource allocations considering practical concerns. Practical concerns include minimizing the level of inter and intra system signalling, signalling overhead and robustness to imperfect inputs. The key objectives of the proposed project which are distinguished comparing to the state-of-the-art and contribute into the field of interest are: i) obtaining fundamental performance limits and scalability characteristics for multiuser secondary system, ii) integrating sensing into the radio resource allocation which enables adaptive sensing, iii) developing low overhead resource allocation algorithms with robustness against uncertain inputs e.g., cross channel CSI, and iv) proposing efficient network architectures based on the vision the proposed framework provides on the trade-offs among different system parameters and practical cons
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Individualised medicine in chronic inflammatory skin diseases' in the context of a Horizon 2020 call.

assistant: **Objectives**

More than 100 million EU citizens suffer from chronic inflammatory skin diseases such as psoriasis and atopic eczema (AE). The diseases imply a devastating life quality similar to that of cancer, and cause direct socio-economic costs in the magnitude of 100 billion Euro each year in the EU. Despite all efforts, psoriasis and AE remain undertreated and the concept of individualised (also called precision) medicine could not be established in the field. Consequently, intensified research is demanded by organisations such as the WHO. Unmet medical needs are 1) a diagnostic gap, 2) lack of prediction possibilities to define the optimal therapy for an individual patient, and 3) a substantial number of non-responders to therapies. Reasons for these shortcomings are the heterogeneity of both psoriasis and AE and insufficient collaboration of clinical specialists, basic researchers, and bio-informaticians. This proposal aims at improving health care of inflammatory skin diseases by implying the concept of individualised medicine. The crucial step towards this goal is the ground-breaking idea to link deep clinical phenotyping to molecular signatures in lesional skin. Deep phenotyping means each patient is characterised by 86 clinical, histological, and laboratory attributes rather than the imprecise state-of-the art approach of rough diagnosing. Each attribute gets assigned to molecular events in lesional skin. Gene regions as well as key pathogenic molecules are identified in a novel gene network of inflamed skin, referred to as BRAIN (biological relevance assigned intelligent network). Candidate targets get validated using state-of-the-art cell culture systems and full skin models. This innovative and ambitious approach will substantially improve our knowledge of the pathogene
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Topological Polaritonics' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Due to their great versatility, photonic systems have been proven to be very powerful platforms for exploring topological physics and for engineering optical devices that are robust against fabrication defects and local perturbations. Right now, the most important challenges that faces this emerging field of topological photonics are (i) to break time-reversal symmetry (TRS) at optical frequencies, and (ii) to implement nonlinearities in topological modes. On the one hand, breaking TRS would allow implementing compact optical isolators and unidirectional waveguides in the edge states of topological lattices; on the other hand, nonlinearities would give rise to exotic effects emerging from the interplay of interactions and topology (e.g. fractional quantum Hall effect, topological solitons, multistability) and allow engineering active optical devices with topological robustness (e.g. topological lasers, diodes, switches...). Based on a multi-disciplinary approach, the objective of this proposal is to tackle both challenges using lattices of cavity polaritons, a half-light/half-exciton quasiparticle well-known for its nonlinear properties. In the first part of this project, we will take profit of the strong expertise of the host group in terms of microcavity etching to investigate nonlinear effects (polariton lasing, soliton formation and instabilities) emerging in the topological edge states of honeycomb polariton lattices. To do this, we will use a lattice with relevant edge terminations and appropriate exciton-photon detuning, and optically pump high polariton densities in the topologicale edge modes. Then, we will demonstrate TRS-breaking, either by using the magnetic moment of polaritons in an external magnetic field or by optically polarizing the exciton reservoir.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'RNA Origami Technology in Cell Systems' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

Biomolecular nanotechnology aims at using the self-assembly principles of nature to create nanostructures and nanomachines for applications in biotechnology, medicine, and materials science. Advanced nanodevices, that sense inputs, do basic computations, and actuate functionality or movement within their nanoscale environment, are referred to as “nanorobots”. With advances in methods for prediction and design of RNA and protein structure, there is now a big opportunity to create complex biomolecular nanorobots. However, it is not clear how to combine multiple functional motifs and how to design the dynamical energy landscapes of molecular machines. In the RIBOTICS research proposal, I will address this challenge by the construction of RNA origami robots that sense, compute, and actuate in cellular environments with the goal of providing components for RNA-based synthetic regulation of living cells. To achieve this goal, we will: (1) Establish a platform for design and characterization of RNA origami robots by developing computer-aided design software and using advanced cryo-electron microscopy and tomography methods, (2) Develop genetically encoded RNA origami robots for control of gene expression and spatial organization of enzymes for metabolic engineering, (3) Develop xenonucleic acid (XNA) origami robots by studying the effects of chemical modifications on structure and function of RNA motifs for applications in controlled gene delivery and biosensing, (4) Develop RNA circuits for control of RNA origami robot systems in cells to develop RNA-based signal transduction pathways for control of metabolism and biosynthesis in S. cerevisiae yeast. If successful, this project will provide a better understanding of the design principles for biomolecular function and provide
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Radiation Innovations for Therapy and Education' (RADIATE), addressing dissemination and exploitation.

assistant: **Impact**

Approximately 45-60% of all cancer patients are treated with radiotherapy. Some of these patients have a good outcome, but in other cases their illness fails to be cured. This may result from distant metastases or from regrowth of the primary tumor. This training network is built on the premise that considerable advances in understanding radiobiology will open novel routes for effective therapeutic intervention with biological targets to improve the outcome of cancer treatment; this progress requires a European-wide effort. This network of radiobiologists, clinicians and scientists with complementary expertise will stimulate outstanding science, meeting the high demand for excellent young academics enhancing Europe´s competitive capability in this highly relevant but underrepresented and fragmented research area. We will strengthen collaborations and technological platforms to develop effective therapeutic strategies for cancer. The failure to eliminate the primary cancer can be placed into 2 categories: the radioresistance of the tumor and the sensitivity of surrounding normal tissue; and the effects of the tumor microenvironment leading to greater overall resistance and altering the immune response to the tumor. This will be combined with translational work designed to identify and implement new therapeutic strategies for use in radiotherapy. Students will benefit from the expertise of the whole, both academic and industrial including unique research technologies that will now be available throughout the network, including a variety of screening platforms, methodology for preclinical cancer therapy and novel radiation and imaging technologies. The European community will benefit from the pursuit of innovative hypotheses, training of new researchers, and dissemination
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'CAPACITY BUILDING NEXUS FOR MONITORING WATER QUALITY IN MULTI-STRESSOR AREAS: PILOT STUDY AT THE HELLENIC VOLCANIC ARC' to be submitted under Horizon Europe.

assistant: **Abstract**

The NEXUS-MONARC project proposes a set of capacity building actions targeting to advance the profile of staff at the department of geology and geoenvironment and collaborating groups at the National and Kapodistrian University of Athens. Through these actions, a holistic approach to environmental monitoring will be developed for the marine environment of the Hellenic Volcanic Arc in the Mediterranean Sea, an environment that is influenced by multiple stressors of anthropogenic and natural origin, such as maritime transport, fisheries, industrial tourism, volcanic activity, hydrothermal venting, and others. The project objectives will be achieved through transferring knowledge and best practices based on the extensive expertise of partner institutions and by orchestrating citizen science activities. Short scientific missions synchronized to citizen science activities will lead to the development of novel collaborative research projects for the coordinating and partner institutions. Furthermore, twinning activities will incite local and international stakeholders from public, policy, and industry to participate and contribute to educational and scientific actions, thus actively improving the marine environment and protecting its inhabitants. Owing to training and collaborative actions, the improved administrative and management practices of the NEXUS-MONARC will be readily applicable to other multi-stressor marine environments in the world.


**Keywords:** multi-stressor, marine, ecosystem, anthropogenic, natural, pollution
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'AFROPEMOTIONS: Rethinking Emotions, Inequality, and Resistance through Afropean Women's Fiction' (AFROPEMOTIONS) targeting Horizon Europe.

assistant: **Abstract**

AFROPEMOTIONS investigates how the emotional entanglements depicted in 21st-century Afropean women’s fiction in English enable discussions of emotional encounter, inequality, and resistance. The project analyses selected novels (2005–2024) set in different European contexts and depicting the experiences of Afro-descendant (im)migrant women exposed to multiple forms of oppression. Emerging studies reveal how prejudices and discriminatory attitudes/practices stem from the proliferation of negative emotions produced by specific habits or patterns of judgment in predominantly white Western/European societies. By combining an affective approach with gender, intersectional and postcolonial critical perspectives and literary and empirical analysis, the project: 1) proposes the first extensive comparative study of 21st-century Afropean women’s fiction in English with a focus on emotions and their socio-cultural and political implications; 2) aims to raise readers’ awareness about the multiple forms of discrimination faced by African (im)migrant women in Europe, in both fictional narratives and real-life contexts; 3) uses Afropean women’s fiction as a critical site to engage in broader conversations about emotions, inequality, and resistance that move beyond mere literary debates.This two-year action will be undertaken under the supervision of Prof. Elisabeth Bekers at Vrije Universiteit Brussel (VUB) and includes two short secondments in Berlin: at Freie Universität (FU), supervised by Prof. Jan Slaby, and at the Leibniz-Zentrum für Literatur-und Kulturforschung (ZfL), supervised by Dr. Gianna Zocco. The project will comprise transversal training, the acquisition of transferable skills, and targeted dissemination and communication activities, including the organisation of focus
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'PAlladium Recovery for CO2 VALorisation' (PARCOVAL), addressing dissemination and exploitation.

assistant: **Impact**

Critical Raw Materials (CRM), incl. Platinum-Group Metals (PGM), are key to enable Europe to meet its 2030 climate and strategic autonomy objectives. Global demand is constantly growing for CRM, the diversification of EU supply is thus imperative to reduce dependencies and improve EU capacity to rely on sustainable value chains. PARCOVAL’s aim is to leverage the recognised catalytic capabilities of radioactive PGM (specifically the palladium -Pd) to demonstrate their potential for use and market. PARCOVAL will create 2 circular loops from 2 wastes: 1) recover Pd from spent nuclear fuel (today vitrified and considered a nuclear waste) and 2) reuse the CO2 produced by an existing industry.Pd will be extracted from streams generated in a spent nuclear fuel recycling plant and valorised as catalyst to perform CO2 electroreduction into CO. Performances achieved into CO conversion will be compared between radioactive Pd and natural Pd catalyst at industrial scale (100cm2 electrodes integrated in electrolyser). Catalytic mechanisms involved will be studied to explain the contribution of radioactive radiation during CO2 reduction. The CO2 will be supplied by industrial production units of anaerobic digestion.Focus will be on the characterisation of the CO generated and the non-radioactive gas contamination to consider a transfer into a non-nuclear environment plant will also be demonstrated. A use case to valorise the CO will be studied to produce succinic anhydride which can be incorporated in polyesters through copolymerisation.PARCOVAL will conduct a Life Cycle Analysis to compare environmental impacts of using radioactive Pd and mining extracted Pd to produce succinic anhydride. Moreover, a preliminary business model will be performed and the market potential of target grou
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'A Novel Antibody-Drug Conjugate for Targeting Tumor-Associated Macrophages in Solid Tumors' (TAM-ADaCT).

assistant: **Innovation**

The project is focused on the development of a groundbreaking Antibody-Drug Conjugate (ADC) specifically designed for macrophage depletion in the Tumor Microenvironment (TME). With a primary focus on breast cancer and solid tumors, this initiative represents a paradigm shift in cancer therapeutics.The presence of Tumor-Associated Macrophages (TAMs) in the TME has been identified as a significant factor in tumor progression and immune evasion. Our proposed ADC will directly target these macrophages, effectively depleting them and thereby creating a more favorable environment for tumor eradication.The primary objectives of this project are as follows:1. To synthesise and optimise ADCs for specific targeting and depletion of TAMs in the TME.2. To demonstrate the efficacy of the ADC in preclinical models, establishing its potential for human application.3. To perform a thorough ""freedom to operate"" analysis, ensuring that the ADC technology does not infringe upon existing intellectual property rights.4. To establish a detailed plan for the commercial development of this ADC, outlining steps for regulatory approval, manufacturing scalability, and market entry.By achieving these objectives, we aim to propel this project from the conceptual stage to a viable, commercialisable medical solution. The successful implementation of this ADC has the potential to revolutionise cancer treatment, offering a targeted approach that could significantly improve patient outcomes. The support of ERC Proof of Concept Grant will be pivotal in transitioning this transformative technology from the laboratory to the marketplace, ultimately changing the landscape of cancer therapeutics.The strategic positioning of Zelula Biopharma (Host Institution) as a spin-off of CIC bioGUNE adds substantial v