RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Density assemblages: intensity and the city in a global urban age' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

DenCity offers a new approach for understanding density and its relationship to the city. Density is a defining feature of the city and urban life. Across the world, density is now at the centre of policy and planning agendas to build cities that are environmentally, economically, socially and politically ‘sustainable’. While there is a lively tradition of research on density in the city, we lack an understanding of the different ways in which high densities are lived and perceived by residents. Existing research provides rich resources for how we might define and represent density, how we might arrive at optimum numbers of people in a given area, and how capitalism builds or reduces densities within and between places globally. However, we lack an understanding of how high density – what I call intensity – is understood and experienced by different urban inhabitants, and the implications for how we understand the contemporary city. Developing a ‘density assemblage’ approach, I propose to examine the ways in which residents differently know and relate to intensity, including how it comes to matter, for good or ill. I do so by examining different cases of intensity in the Asian city, from travel and transport hubs, and slums to rooftops. While the 20th century witnessed a general global decrease of urban density in favour of urban sprawl, many Asian cities continue to densify. Asia is the densest and most urbanized part of the planet, and the trend is predicted to continue. I will examine some of the highest densities in the world, including in Hong Kong, Mumbai, Manila, Dhaka, and Tokyo. The different ways in which intensity becomes known and comes to matter for residents will be a vital challenge for understanding life in the urban 21st century, and for how we understa
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Evaluation of lentivirus dna vaccination strategies in sheep' will create measurable scientific, societal and economic impact aligned with Fifth Framework.

assistant: **Impact**

Lentivirus vaccines have proven difficult to develop to date. The reasons for this include a lack of information on target antigens, protective immune responses, and effective vaccine strategies. We propose to evaluate DNA vaccination strategies in sheep challenged with maedi visna virus (MVV). Sheep will be immunised with MVV core or envelope genes or a combination of these via the skin (by gene gun) or mucosal tissues (using Salmonella vehicles). The effects of including genes encoding IFNg or IL4 during priming will also be investigated. Animals will be boosted with recombinant Adenovirus encoding the MVV genes. Immunological variables as well as virus load and disease will be determined before and after challenge. The project will help to identify protective virus antigens, provide useful information on immune correlates of protection, and indicate whether mucosal or cutaneous immunisation correlates with protection.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Discrete Multi-physics modeling of hydrate blockage in pipelines' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Gas hydrates are crystalline compounds where a cage-like water structure surrounds an organic molecule such as methane. They often form in oil and gas pipelines, where they stick to the inner walls clogging the flow. When this happens, the blocked section of pipe needs to be cut out and replaced, resulting in long shutdowns of production. The oil and gas industry spends more than 200 million euros per year to prevent such blockages and industry sources estimate the total costs for prevention and lost production due to hydrates in the order of billions. Available commercial software packages generally only focus on the thermodynamics of hydrate formation, but recent scientific literature emphasizes the interconnected role of thermodynamics with heat transfer and hydrodynamics. To better understand this phenomenon and to devise techniques to control/minimize its effects, we aim to adapt a novel multi-physics methodology called Discrete Multi-physics and derive from it computational tools to study and predict hydrate blockage. Based on Discrete Multi-physics, we will set up a mathematical model that links thermodynamics, heat transfer and hydrodynamics and generate an Open Source software freely available to other academics and practitioners.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Nanoscale Phenomena and Structures in Bulk and Surface Phases' (NANOPHEN) under Sixth Framework.

assistant: **Objectives**

The basic objective of the project is to improve and reinforce the research capacity of the Institute of Physical Chemistry at the Bulgarian Academy of Sciences in the field of nanoscale phenomena in bulk and surface phases so as to foster the impact of nanotechnologies on national scientific and economic development. The project aims at: -enhanced collaboration with similar MS institutions and formation of stable networks -improving the participation in ERA and particularly in FP6 initiatives -formati on of a critical mass of highly qualified young researchers with multidisciplinary scientific skills -improving the technical level of key scientific equipment in IPC-BAS and thus enlarging the scope and efficiency of  experimental techniques, which are w idely used incl. for collaborative research with MS partner laboratories.  The objectives will be achieved by: -enhanced exchange of scientists and expertise -organizing on-line acting Virtual international research group -initiating new networks -organ izing exploratory workshops on basic thematic priorities of the project -creating new job opportunities and better working conditions -intensive practical (experimental and computer) training for young researchers -increasing expertise by advanced study, c o-tuition by MS experts -upgrade of key scientific equipment in IPC-BAS. Addressing the priorities of the Specific Call, the proposed support actions will result in: -increasing the quality and scope of IPC-BAS research activities in the field of NMP -a dding new value to the national scientific potential in the thematic priority of the NANOPHEN project -opposing the negative trend of age-misbalance in science and ?brain-drain? of Bulgarian young researchers -elaborating a new concept for coupling multidi sciplinary pra
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Deformation control on flow and transport in soft porous media' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Fluid flows through soft porous media are ubiquitous across nature and industry, from methane bubbles rising through lakebed and seabed sediments to nutrient transport in living cells and tissues to the manufacturing of paper products and many composites. Despite their ubiquity, flow and transport in these systems remain at the frontier of our ability to measure and model. A defining feature of soft porous media is that they can experience deformations that transform the pore structure. This has profound implications for the transport and mixing of solutes and the simultaneous flow of multiple fluid phases, both of which are strongly coupled to the pore structure. The goal of this project is to shed new light on flow and transport in soft porous media by studying a series of three canonical flow problems (tracer transport, miscible viscous fingering, and two-phase flow) across soft adaptations of three classical model systems (a soft-walled Hele Shaw cell, a quasi-2D packing of soft beads, and a cylindrical 3D “core” of soft beads). These flow problems and model systems have been thoroughly studied in the context of stiff porous media, allowing us to leverage decades of previous work and focus exclusively on the new behaviour introduced by “softness”. We will collect an extensive set of new, high-resolution experimental observations in each of these model systems, and we will reconcile these observations with mathematical models based on the traditional approach of upscaled constitutive functions. By updating this traditional approach to account for deformation, we will provide a new, pragmatic class of continuum models that capture the leading-order features of flow and transport in soft porous media. Our results will jumpstart the field of flow and transport in soft p
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'NAPES - Next Generation Analytical Platforms for Environmental Sensing'.

assistant: **Objectives**

GOALS:The current state-of-the-art for autonomous environmental instruments monitoring the chemical and biological status of our water is based on flow systems that employ conventional approaches to sample/liquid handling, which makes them prohibitively expensive (often >€20K per unit) in terms of up-scaling deployments. This project will investigate ways to deliver revolutionary advances in liquid/sample handling combined with new approaches to performing sensitive in-situ analytical measurements.  Our goal is to drive down the unit cost of these instruments by orders of magnitude to levels that can create a tipping point, at which the technology becomes ubiquitous.OUTCOMES:•Novel technologies that will contribute significantly to the realization of next generation autonomous analytical instruments for distributed environmental monitoring.•New services based on the information generated by these instruments in real deployment scenarios.•Photoactuated polymer valve structures fully integrated within microfluidic channels•Highly sensitive detector integrated with microfluidics sample preparation•Photocontrolled functions such as filtering, preconcentration, uptake and release, surface activation/passivationPrototype components will be integrated with existing autonomous sensing devices, and after lab based trials deployed at wastewater treatment plants and in the general environment. This strategy will enable risk to be managed by testing the novel biomimetic fluid handling components with existing detectors (e.g. colorimetric methods for nutrients). In a similar manner, a novel E coli sensor will be assessed using validated fluid handling technologies in the existing devices.  This strategy will allow the biomimetic fluid handling and advanced detector elements of the r
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Biogenic Organotropic Wetsuits'.

assistant: **Innovation**

Extracellular vesicle (EVs) nanoparticles are the universal agents of intercellular and inter-organismal communication “made by cells for cells” to shuttle lipids, proteins and nucleic acids, EVs mediate physiological processes and help to spread various diseases, including cancer and infections. Their innate navigation performances take origin in the unique structure and composition of their membrane (which is to date inaccessible to synthetic mimics). The main goal of the BOW project is to explore and consolidate the technology able to impart biological surface precision, circulation and targeting abilities of EVs to superparamagnetic nanodevices (Magnetic Bead Devices, MBDs) by “dressing” them with a single- or multi-layer “wetsuit” of EV membrane “fabric”. This will proof and set a general, viable paradigm to recapitulate key biomimetic functions – including camouflage to the immune system and organ site/tumor targeting – to any synthetic nanodevice, while being disruptive as a first example of biogenic nanotechnology. If successful, such a non-incremental technology will promote the progress of implantable nanodevices and nanomaterials towards sustainable production and clinical translation, contributing to strengthen and keep in the lead position European biotechnology and impacting life quality for people. Major objectives include: (i) production high-grade EVs with biomimetic and organotropic functions, (ii) synthesis and functionalization of MBDs, (iii) engineering a microfluidic device for streamlined fabrication of EV membrane coated MBDs (evMBDs) (iv) evaluation of evMBD biological performances and nanotoxiciy in-vitro, ex-vivo and in-vivo. BOW will be made possible thanks to a balanced ecology-biology-biophysics-chemistry-engineering matrix, of well-establi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Genome organization and transcription at the beginning of development', explaining its relevance to EU policy priorities under Sixth Framework.

assistant: **Impact**

We want to address the question of how DNA replication and transcription are coordinated in the early stages developing sea urchin embryo. In this system, even though the embryonic cells are involved in fast-paced cell division transcription begins very early in development. We think that this is possible because the early-stage transcripts constitute a group of GC rich sequences, in the otherwise generally GC-poor and (by vertebrate standard) homogeneous sea urchin genome. This GC richness may be responsible for a positional distribution of these sequences in regions of the genome more readily accessible to the transcriptional apparatus even during fast cycles of chromosomal duplication-condensation.The sea urchin embryo is a system of choice to test this hypothesis because:1) the genome information necessary for the study is (soon to be) available;2) a comprehensive picture of the early development, described in its detailed regulatory gene network circuitries, is being built over the recent years;3) this model system offers great experimental manipulability.The study proposed offers us the opportunity of linking genome organization with transcriptional activity and understanding what the functional relevance of this is in development. The system c hosen provides the ideal portal to understand how the evolutionary process has shaped the genome to make it transcriptionally efficient from the early stages of embryonic life.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'affecTive basEd iNtegrateD carE for betteR Quality of Life' (TeNDER) targeting Horizon 2020.

assistant: **Abstract**

With an increasingly growing population in Europe, cognitive impairments as well as heart diseases are a major social and health issue. 1.2 million people in Europe are affected by Parkinson's disease (PD) while  Alzheimer’s disease remains one of the biggest global public health challenges our generation is facing, while Cardiovascular disease represented the 31% of all global deaths in 2016.Based on these facts, the affecTive basEd iNtegrateD carE for betteR Quality of Life TeNDER project will create an integrated care ecosystem for assisting people with chronic diseases of Alzheimer’s (AD), Parkinson’s (PD) and comorbidity with Cardiovascular Diseases (CVD) through the use of affect based micro tools. These microservices will recognise the mood of a person and thus adapt the system’s probes to the person’s needs via a multi-sensorial system, even in the most severe cases, and match with clinical (from Electronic Health Records EHRs) and clerical patient information, while preserving privacy, monitoring the ethical principles, providing data protection and security, with the result of an increased Quality of Life (QoL). In addition, interactive communication and social services will strength the elderly support, extending their autonomy and care supply chain.TeNDER will perform 5 large scale pilots, involving 5 user partners and 1500+ TeNDER final users in 4 different European regions, with at least 735 patients (+40% in the patients control group, making a total of 1030 patients), 85 health professionals (physicians mainly), 30 social workers, 570 caregivers (professional and relatives) and 60 other staff (clerks, Hospital IT support, etc.), to provide tailor suited integrated care services to promote wellbeing and health recovery.TeNDER will provide 4 different scen
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Detecting slow deformation signals preceding dynamic failure: A new strategy for the mitigation of natural hazards' (SAFER) targeting Seventh Framework.

assistant: **Abstract**

We propose a new strategy based on an interdisciplinary unitary and integrated approach aimed to monitor and detect small signals of impending failures and mitigate natural hazards, by:1) quantify of critical damage thresholds triggering dynamic failure, throughout the ‘In situ’ identification of characteristic slow deformation signals and accelerating patterns before impending ‘large scale’ failure events;2) set up of early warning models for forecasting the time of rupture with application to natural hazards;3) transfer of knowledge between multiscale signs of slow deformation before dynamic failure from the laboratory to field.In detail, we propose to develop innovative strategies for forecasting dynamic ruptures by monitoring an unstable patch of the Gollone landslide on the Italian Western Alps, prone to the development of rock falls and repeated failure episodes, preceded by neat and long lasting episodes of slow deformation. In order to do so, we aim to identify the characteristic signs of impending failure, by installing a “site specific” microseismic monitoring (1-200kHz) system for acoustic emission/microseismic (AE/MS), integrated with a conventional monitoring for seismic detection (1-10Hz) and ground deformation monitoring (strainmeters, geophones and accelerometers).The installation of the monitoring network will be accompanied by a detailed geophysical characterization of the test site in order to establish the best nodes position and internal characteristics of the monitored landslide. Rock physical and mechanical characterization along with rock deformation laboratory experiments during which the evolution of related physical parameters under simulated conditions of stress and fluid content will be studied and theoretical modelling will allow to come up
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'A probabilistic framework for assessing polar wander – Constraining paleolongitude in deep time' (TANGO) targeting Horizon 2020.

assistant: **Abstract**

The quantification of past plate motions is of paramount importance to advancing our understanding of Earth’s evolution. Plate motions of the last ~130 Ma are well-resolved from magnetic isochrons and hotspot tracks, but as those records are progressively destroyed by subduction, they cannot be used in deeper time. Before 130 Ma, plate motions can only be quantified through the study of paleomagnetism, but analytical limitations have so-far prevented us from using this tool to its full potential. For example, owing to the axial symmetry of the Earth’s magnetic field, the determination of paleolongitude from paleomagnetic data –although theoretically possible– has long been considered an intractable problem. TANGO will capitalize on this untapped potential through an innovative and cross-disciplinary approach integrating modern data-science techniques into paleomagnetic research, thereby opening a new research frontier.Aiming to contribute towards the neglected issue of paleomagnetic precision, I will focus on state-of-the-art computer-intensive statistical methods to provide the conceptual basis for a much needed probabilistic framework for paleomagnetic research. These efforts will allow me to provide paleogeographic reconstructions with uncertainty estimates for the first time. With that framework, through application of unsupervised learning methods, I will also be able to tackle the outstanding problem of paleolongitude determination in deep geologic time, which remains one of the most important challenges in modern geophysics. Such novel and quantitative methods development is strongly complementary to the core research efforts at CEED (University of Oslo) to explore the missing links between plate tectonics and mantle evolution. In this pursuit, TANGO will reinfor