RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Protect and promote Crop Wild Relatives'.

assistant: **Objectives**

Crop wild relatives (CWR) are wild plant species genetically related to cultivated crops. Their untapped diversity can enhance resilience to biotic and abiotic stress and the nutritional quality of modern crops. Wheat, sugar beet, and oilseed rape were selected by Pro-wild because of their importance to food security and EU farmers and because some of their wild relatives are endemic to Europe. Moreover, these CWRs constitute a rich and under-exploited resource needed to face challenges linked to climate change and the transition to low-input agriculture. The genetic diversity and vulnerability of these CWRs must be better characterized to optimize their conservation and utilization. The objectives of Pro-Wild are to identify priorities for in-situ conservation of the selected CWR gene pools, to survey and complement CWR genebanks collections, and to increase the use of CWRs in crop improvement. Pro-Wild associates 18 partners from 11 EU and associated countries with expertise in ecology, conservation, genomics, pathology, microbiology, plant breeding, agriculture, and sociology. Pro-Wild will compile and analyse CWR occurrence maps and perform new in-situ collections. It will predict the vulnerability of several CWR species and populations to ongoing climate changes. Ex-situ collections will be complemented with endangered CWRs accessions. Pro-Wild will investigate the resilience of CWR collections for relevant biotic and abiotic stresses. The identification of CWR-derived desired traits and their transfer into elite backgrounds will be done to promote CWR use. Overall, Pro-Wild specific goals will be coordinated with input from breeders, farmers, and consumers. Pro-Wild outcomes will contribute to European Green Deal initiatives through research, education, and traini
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Optimisation of cogeneration systems in a competitive market environment (OSCOGEN)', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

The efficient operative cogeneration system supports the energy and environmental policy objectives of the EU. Additionally this helps to increase the competitiveness of CHP systems and hence the share of environmentally sound combined heat and Power production. In view of this background the aim of the project is to develop an optimisation tool for the cost and resource efficient operation of CHP systems and to apply it within a case study in cooperation with a utility. This tool will be based on stochastic optimisation and genetic algorithms.Compared to existing approaches this new approach promises to find faster more accurate solutions for the operation of CHP systems in a competitive energy market given the fact that uncertainties are adequately taken into consideration.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'COMMANDEER: Disrupting microbial resistance using rationally designed signalling molecules' (COMMANDEER).

assistant: **Innovation**

Cystic Fibrosis (CF) is an inherited disease which affects 100,000 people worldwide and is prevalent in European populations. CF causes the body to produce an abnormally sticky mucus in the lungs making patients susceptible to serious bacterial infection. By age 8, 50% of CF patients are infected with Pseudomonas aeruginosa increasing to 80% by 20 years of age. Eventually, the infecting strains of bacteria become resistant to antibiotics and remain a chronic inhabitant of the lungs of CF patients until they succumb to respiratory failure, usually by the young age of 30-35. Approximately 60% of CF patients are co-infected with Burkholderia cenocepacia that settle into the thick mucus of the airways. These bacteria have evolved a special type of defence mechanism to antibiotics whereby they excrete a chemical messenger on treatment. This chemical messenger -Diffusible Signal Factor or DSF - activates bacterial biofilm formation. Previous work has shown that DSF effectively behaves as an ‘emergency flare’ to other bacteria, which produce a biofilm in response. This biofilm acts as a shield which protects the bacteria from the effects of antibiotics.As a key fits in a lock, DSF fits into bacterial receptors and “switches on” biofilm formation. In this COMMANDEER project, we will synthesise molecules which mimic DSF and fit into the same biological receptors. However, due to subtle changes in their design, our molecules will “switch off” biofilm formation. Using this novel strategy of effectively commandeering the bacteria’s signalling system, we will disable biofilm formation, making the bacteria susceptible to antibiotics once again. We will adopt a multidisciplinary and collaborative approach combining the talents of chemists in Ireland and microbiologists in the UK. This
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Euroscience Open Forum 2012' (ESOF2012) under Seventh Framework.

assistant: **Objectives**

ESOF is an interdisciplinary, pan-European meeting, held under the auspices of Euroscience, which aims to:Showcase the latest advances in science and technologyPromote a dialogue on the role of science and technology in society and public policyStimulate and provoke public interest, excitement and debate about science and technologyWe will achieve this by bringing together 5,000 scientists, business leaders, government officials and international media to discuss the best European science and address all of the major global issues, including energy, climate change, food and health.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Validation and Comparitive Multi-Omics Benchmarking of Fluid-Derived Volatilomics Biomarkers for the Prevention and Early detection of Schizophrenia'.

assistant: **Concept**

Schizophrenia (SZ) impacts around 1% of the global population, posing diagnostic challenges that lead to a misdiagnosis rate of 23-40%. The need for reliable biomarkers is crucial to improve early detection and treatment outcomes. VOLABIOS aims to revolutionize SZ management by harnessing innovative real-time and portable spectrograph technology to validate volatile organic compounds (VOCs) as non-invasive and cost-effective biomarkers detectable during the early stages of the disease. This entails extensive data analysis, prospective clinical studies involving 3,692 subjects across six centres, and a blind validation study with 1,000 subjects, focusing on longitudinal monitoring of at-risk individuals to identify early SZ transition. To further substantiate the efficacy of VOCs and gain profound insights, VOLABIOS will integrate VOC analysis with genomics, proteomics, and transcriptomics. This integration will be supported by a biobank comprising approximately 4,000 samples and a dataset consisting of 9 million records. By considering external and personal risk factors as well as biological responses, VOLABIOS aims to unravel intricate correlations that contribute to SZ development. This comprehensive approach will enhance prediction accuracy, facilitate early detection, and improve management strategies. Furthermore, VOLABIOS plans to explore the real-time effects of validated VOCs through controlled in-vivo experiments using animal models, providing valuable information about associated cellular and molecular pathways. VOLABIOS's endeavours to validate and establish EU-wide SZ diagnosis protocols are set to significantly enhance patient care and healthcare efficiency, marking a substantial step forward in addressing the complexities surrounding SZ.


**Keywords:** Sc
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Magneto eTrieve thrombectomy system EIC funding application' (MGN-2024-10).

assistant: **Concept**

In the fields of stroke and PE care, current thrombectomy tools rely on outward radial forces against the vessel wall to disrupt and retrieve clots limiting treatment of distal occlusions and potentially leaving clot fragments behind.Generating an attachment force that is attractive by nature with the eTrieve™ system developed by Magneto allows to attract clot with minimal interaction with the vessel wall, enabling access to distal locations and minimizing fragmentation. The eTrieve™ system developed by Magneto is the first and only system that utilizes the electric properties of blood clots in order to facilitate their removal.The urgent need to invest in modern technologies for European healthcare systems is underscored by the pressing issues of stroke and pulmonary embolism, major causes of death and disability worldwide. With aging being a primary risk factor for stroke and Europe's population aging rapidly, the incidence of these conditions is poised to skyrocket.We founded Magneto in 2016, and target a total addressable market across both PE and stroke indications of €5B (EU+US markets), with a SAM totaling at €1B with device pricing aligned with reimbursement: $3-5k for stroke devices and $10k per procedure for PE.Our team includes experienced MedTech industry veterans, with specific and extensive knowledge in the cardiovascular space, and a talented and creative R&D team constantly driving the company innovation forward.At Magneto, our vision is not just about developing a device; it's about revolutionizing patient care for stroke and PE. Our ambitious goals encompass innovation, patient well-being, accessibility, clinical excellence, sustainability, and collaboration. Through our relentless pursuit of these ambitions, we are poised to leave an indelible mark on
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Variable Impedance Actuation Systems Embodying Advanced\nInteraction Behaviours'.

assistant: **Innovation**

Most of today's robots have rigid structures and actuators which require complex software control algorithms and sophisticated sensor systems in order to behave adaptable, compliant, and safe in contact with unknown environments or with humans. Moreover, in terms of energy efficiency, peak force and speed, these robots are still considerably weaker than their biological archetypes. An alternative design approach is to build actuators with physically adjustable compliance and damping, which are able to store and release mechanical energy, react softly when touching the environment, and provide an intrinsic degree of safety, just like muscles do. The ability to vary the impedance (i.e., stiffness and damping) is crucial in order to optimally adapt to a large variety of situations. However, the technological realisation of such systems is very challenging, having many open problems in terms of materials, design, actuation, and control concepts. VIACTORS addresses the development and use of safe, energy-efficient, and highly dynamic variable-impedance actuation systems which will permit the embodiment of natural characteristics, found in biological systems, into a new generation of mechatronic systems. Target outcome of the project is that of obtaining the intended physical interaction and motion behaviours of the robotic system intrinsically by its physical structures to the maximum extent possible. This will not only save computational and communication costs for controlling the robot motion; it will also allow us to match the task requirements in a natural and highly dynamic way as it can be observed in biology. And, perhaps most important, to provide a powerful, human-like physical interface which can be accessed by higher (cognitive) intelligence levels without having
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fifth Framework proposal on 'Towards a vaccine against helicobacter pylori'.

assistant: **Innovation**

Studies in animal models have demonstrated prophylactic and therapeutic immunization against H. pylori, the causative agent of peptic ulcer and the major risk factor for gastric cancer. Vaccine candidates are in development and clinical trials are planned . The convolution of H. pylori with the human races has resulted in variation in strain genotype, immune response and disease progression which may compromise global vaccine efficacy. Here we address three fundamental questions relevant to a vaccine capable of conferring global protection :1) Can antigens capable of conferring global protection against geographic strain variants be designed,2) Can correlates of protection based on cytokine expression and immune system polarization be defined and3) Will concurrent infection with strongly immune polarizing pathogens compromise vaccine efficacy. Parallel studies in Europe and in China, where over 80% of the population is infected, are planned.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Ground-breaking Research on Employment and Environmental Transitions Ahead' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

This project aims to empower the researcher to develop novel knowledge and research skills to deconstruct the trade-off between labour and environmental sustainability, by analysing the implications of labour law with a critical societal problem: the global environmental crisis. This fellowship will develop a systemic and integrated approach to the legal analysis of forefront drivers of change in society, i.e. climate change and the need to promote a Just Transition to a low-carbon economy. By combining a variety of legal approaches and methods, it will contribute to advance and integrate the existing frontier research on labour and environmental sustainability, as well as to breach silos approaches to sustainable development and the correlated transitionary policies and legislations. This project will be implemented with a mix of traditional and innovative training activities (mostly training-through-research) based on individual and cooperative learning between the researcher and the supervisor. Paolo Tomassetti (the researcher) will carry out his fellowship at the Centre de droit social of Aix-Marseille University (the host institution), under the supervision of professor Alexis Bugada (the supervisor), for sixteen months. To ensure the overall quality of the project, in addition to three scientific publications, international conferences and a MOOC summer school, an Advisory Board will be established as a privileged audience of the project results and a multiplier of its dissemination through the scientific community.


**Keywords:** Labour, jobs, environment, just transition, sustainable development, industrial relations, unions, collective bargaining, green economy
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'New International Monetary and Financial Environment' (NIMFE) targeting Horizon Europe.

assistant: **Abstract**

The structure of the international monetary and financial system has first-order implications for capital flows, financial stability, the value of currencies and the way shocks propagate across countries. The world is changing rapidly: the share of the United States and Europe in international trade has declined, while the share of Asia has increased since the 2000s. International finance is still dominated by the US dollar, but China is emerging. There are wealth transfers due to the restructuring of commodity markets and the green energy transition. These constitute significant transformations of the international monetary and financial environment. This proposal aims to study interlinkages of countries to shed light on global cycles and transmission of shocks and policies of dominant currency powers over time. It has five tightly interconnected parts: (i) construct the trade, financial and commodity networks of countries to understand interdependencies and the role of main Central Banks, in particular the People’s Bank of China (ii) focus on the channels of international transmission of shocks to the real economy at the firm level using rich micro-data sets (iii) study the international finance network at the granular level and provide a brand new empirical and theoretical analysis of determinants of currency values (iv) uncover granular evidence on hedging strategies of economic actors facing those shocks using unexploited data sets (v) analyze changes in the structure of commodities international demand and supply networks (e.g. rare metals) using an original methodology based on textual analysis and track wealth transfers and their implications. These five complementary research streams will together elucidate the anatomy of the changing international financial an
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Exhumation mechanisms of deep crust and formation of metamorphic domes in orogens: a Synergy between naturalistic and numerical approaches' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

This study focuses on the genesis of metamorphic domes and gives fundamental insights on the thermo-mechanical behavior of the deep crust and its relationship with the upper crust. This understanding is essential in order to decipher transfers of mass and heat within the crust and related economic issues and seismic hazards. This project is original as it establishes a strong multidisciplinary synergy between field studies, quantitative petrochronology and numerical modelling. The candidate will spend the outgoing phase at the School of Geosciences in Sydney (Australia) and the return phase at Géosciences Montpellier (GM), University of Montpellier (UM, France). Dr Cenki-Tok is associate professor, well versed into naturalistic approaches. Benefiting from an intensive training in numerical modelling by A/Prof P. Rey at U Sydney will allow her to gather a unique combination of competences both naturalistic and numerical. Sydney is internationally recognised for geodata synthesis assimilating the wealth of geological and geophysical big data into a 4D Earth model. The return phase and knowledge transfer to GM will be supervised by Dr. D. Arcay. The complementary skills acquired during this GF will make her an ideal candidate for a Professorship in Europe. A special attention will be paid to disseminate our results to a large audience, using the various means well established at UM. A scientific workshop will be organised in the Montagne Noire dome (France) in order to bring together a multidisciplinary group of geoscientists. This highlight will significantly contribute to the international recognition of UM. Finally, UM has a long-standing experience in the management of European projects, funded research and training grants. The assistance of the academic, technical and