RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Contained Molecular Farming – Controllable Contained Systems for High Yield and Consistency', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

The CoMoFarm project will establish high-yielding production systems for pharmaceutical and industrial proteins based on plants, plant tissue and plant cells. The aim is to develop systems in which both the production host and the product itself show consistent yield and quality. The project will include a comparison of four alternative systems – hydroponic plants, root cultures, moss and suspension cells, and will involve the evaluation of different species, strain and process optimization, scale-up, downstream processing, protein characterization and process evaluation in terms of regulatory compliance. As well as furthering the development of an emerging production technology, the project will incorporate numerous innovative elements such as in-process monitoring and automation of environmental parameters to maintain a consistent environment and optimize protein yield and homogeneity, novel downstream processing technologies and innovative bioreactor and hydroponic designs to maintain plant health and ensure production according to good manufacturing practice. This project will have an immense impact on the biopharmaceuticals industry, by allowing SMEs interested in molecular farming to develop plant-made pharmaceuticals without worrying about regulatory constraints or poor investment prospects. This will go a long way to establishing molecular farming as a feasible industry within Europe, and will open new revenue streams for companies currently not interested in (or aware of) molecular farming, e.g. horticulture companies and nurseries. The cost of drugs will also begin to fall, which will positively re-enforce the benefits of plants and lead to greater growth in the market.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Genomics of Luminescence in Mycena Mushrooms' (GLiMMer).

assistant: **Concept**

Sailors called it burning of the sea, Shakespeare described it as pale fire and Aristotle named it cold light. The glimmer they witnessed was light emitted by living organisms or bioluminescence. While it represents one of the most striking examples of convergent evolution across the tree of life, in Fungi it has a single origin in the Agaricales order, Basidiomycota. In particular, Mycena, a large genus of mushroom-forming fungi, includes most of known bioluminescent species together with hundreds of species that lost the ability to emit light. In GLiMMer, I will study the evolution of fungal bioluminescence and test the hypothesis that multiple, lineage-specific mechanisms led to the convergent loss of this trait, providing clues for its ecological relevance. To date, Mycena lacks a robust phylogenetic framework and is heavily under sampled. Fungarium collections, such as the one at Naturalis, preserved thousands of Mycena specimens over the past centuries. Thanks to new high-throughput sequencing methods these collections are being transformed in genomics resources, bridging taxonomy and evolution. In GLiMMer, my expertise in fungal genomics will serve to develop a genome-based classification of Mycena, that combines contemporary and museum specimens. I will generate assemblies of 100 representative species using short-read sequencing. Next, I will extract phylogenetically informative loci to design a target sequence capture method for recalcitrant museum specimens for the first time in mushrooms. Then, I will use the new classification to select reference species and obtain chromosomal-level assemblies using long-read sequencing. Finally, with genome-wide synteny analyses I will investigate the evolutionary circumstances that led to the birth and death of biolumines
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Epigenetic mechanisms controlling hypoxia and pathogen Stress responses in plants'.

assistant: **Innovation**

Climate change is a global problem that is drastically changing our planet. Increased precipitation in Northern Europe has caused major crop losses, in part due to the oxygen deprivation experienced by the waterlogged roots. In mammals, epigenetic mechanisms (histone demethylation) have recently been identified that play a major role in the response to low oxygen levels (hypoxia), and response to infection. There are striking similarities between the mammalian and plant responses to hypoxia and infection. My preliminary analyses suggest that the epigenetic mechanisms that control these responses in mammals may be conserved in plants. EpiStress aims to determine if major changes to the epigenetic landscape underlie (i) gene expression changes in response to hypoxia and/or immune response in plants; (ii) the trade-off between the hypoxia and immune programs. These aims will be achieved through three objectives; (i) determining if histone demethylases are novel players in the regulation of hypoxia response in the model plant Arabidopsis thaliana; (ii) testing if histone methylation or acetylation changes underlie the trade-off between hypoxia response and immunity; (iii) describing the epigenetic changes that occur in response to hypoxia in barley (Hordeum vulgare) and if these changes can explain corresponding gene expression changes. Fundamental mechanisms will first be established at Maynooth University, Ireland under the supervision of Dr. Emmanuelle Graciet. The potential for crop adaptation to climate change will be explored during a secondment at the state agency Teagasc, Ireland under the supervision of Dr. Ewen Mullins, using barley, Ireland’s most widely grown tillage crop. A combination of genetics, hypoxia and pathogen treatments, chromatin immunoprecipitation
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'PRODUCT DATA TRACEABILITY FROM CRADLE TO CRADLE BY BLOCKCHAINS INTEROPERABILITY AND SUSTAINABILITY SERVICE MARKETPLACE' in the context of a Horizon 2020 call.

assistant: **Objectives**

In EU a garment is worn an average of 3 times in its life, with €400 Bln lost a year discarding clothes which can still be worn and 92 Mln tons of waste, 87% of clothes ending up in landfills. But due to growing awareness on ethical and environmental impacts, 66% of consumers are ready to pay more for sustainable products . TRICK will provide a complete, SME affordable and standardised platform to support the adoption of sustainable and circular approaches: it will enable enterprises to collect product data and to access to the necessary services on a dedicated marketplace, open to third party solutions. TRICK demo will be run in 2 highly complex and polluting domains: textile-clothing as main pilot and perishable food for replication. EC estimates that up to 10% of the 88 million tons of food waste generated annually in the EU are linked to date marking, with associated costs estimated at €143 billion. Secured traceability will rely on the data needed for the preferential certification of origin (PCO), used for duty calculation. It will be certified by Customs as member of the consortium, representing anti fraud public forces. The data extracted by the fiscal documents for the PCO will be integrated with the bill of materials, saved in the Blockchains (BC) per each lot of production to grant traceability continuity, and with the additional ones to enable the six services provided by TRICK: traceability, circular assessment, PEF, health and social assessment, A.I. for anti counterfeting. BC will secure information through the whole process, ending to consumers for informed purchasing. Data confidentiality and privacy will be granted by the exploitation of Blockchains smart contracts while the adoption of different technologies will be solved by the development of Blockc
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'An innovative intruder detection hidden technology based on Controlled Magnetic Fields able to detect threats before happening' (2014-2020).

assistant: **Concept**

The current perimeter protection systems for critical infrastructure market is valued at €4.12 billion market growing at a CAGR of 7.1%. Rise in government investments in the critical infrastructure sector, need for reduction in manpower cost, and increasing need for security against terrorist attacks are among the main factors responsible for the growth of the perimeter intrusion detection systems market across the globe.Systems such as fiber optic or microwave sensing technologies available in the market suffer from drawbacks associated with false alarms (40% false alarms on average) since they are unable to differentiate between humans, objects and animals. Moreover, existing products are not efficient in operation because both sensors and cameras need to be always operational to be prepared in case of intrusion (contributing to 60%-80% energy inefficiency).WARDIAM PERIMETER system is Ontech’s new product for industrial security specifically targeting critical infrastructures. It is able to do surveillance of large areas close to a building or walls. The sensors monitor the environment continuously and trigger an event when it detects a person in the surrounding (preventive alarm together with video capture) and followed by another trigger in the case there is an intrusion (intrusion alarm). Main advantages are: Preventive detection (threats are detected even before they have been carried out), discriminative (CMF technology is able to distinguish if intrusion is provoked by a human, an animal or an object), hidden system (technology can be installed inside the fence), differentiating between distinct alarm levels (grade of threat can be measured distinguishing between loitering, touching or climbing the fence), tracking and identification of the intruders (collabora
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Development of ceramic and multi material components by additive manufacturing methods for personalized medical products' (CerAMfacturing).

assistant: **Concept**

The cerAMfacturing project will develop a completely new approach for ceramic multi material additive manufacturing which will allow series production of customised and multifunctional components for manifold applications for obtaining property combinations, like electrical conductive/electrical insulating, dense/porous or two-colored components. In five case studies demonstrators for personalized medical products – micro surgical tools, implants, and remedies – such as consumer products will be manufactured starting with the patient specific physical dimensions and ending with components validated under practically relevant conditions.  For achieving these goals manifold tasks will be solved starting with method and device development. Especially suspension based additive manufacturing methods will be developed and qualified in cerAMfacturing, because this route promises a much better component performance in comparison to powder based methods. Multi material applications play a dominant role in the project. Beside ceramic/ceramic also ceramic/metal material combinations will be developed. For that purpose either additive manufacturing methods will be qualified or AM methods will be combined with conventional shaping routes like tape casting or ceramic injection moulding. The last mentioned combination of technologies will allow the individualisation of large series production components. Appropriate control methodologies to guarantee a high quality level of the custom made products will be implemented. The cerAMfacturing project will provide the technical equipment for combining AM steps with conventional ceramic shaping routes.


**Keywords:** additive manufacturing of ceramic components for medical applications,  multimaterial approach
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Coating studies for microstrip gas chambers' (1994-1998) under Fourth Framework.

assistant: **Objectives**

Research objectives and content Gas Microstrip Dectectors (MSGC) are devices which allow to measure with high precision the trajectory of a charged particle. The ionisation signal which is produced in the gas volume of the MSGC is amplified and collected by very fine metal strips placed on a thin glass substrate. At the Large Hadron Collider which is in construction at the European Center of Particle Physics, CERN, a large scale application of these detectors is foreseen because conventional wire chambers can not function in the very high radiation environment of the accelerator. To avoid that MSGC also suffer from radiation damage and electrical instabilities, the glass surface is coated with a thin conducting skin such as diamond-like materials, and the strip are made from gold. The research project proposed here will deal with the behavior of such substrates using varying surface compositions to find the optimum solution for the planned detectors. The research shall be carried out dominantly at the Institut fuer Experimentelle Kernphysik, Karlsruhe University, which offers appropriate laboratory equipment and an excellent means Of diagnosis (X-Ray and neutron beams). Training content (objective, benefit and expected impact) Even though this research is primarly oriented towards elementary particle physics, we will investigate the possibility of applications in industry and medecine. This will be facilitated by the fact that the institute is located inside a large research center (Forschungszentrum Karlsruhe) and by ist good connection to the Frauenhofer-Gesellchaft in Braunschweig. Iks with industry / industrial relevance (22)
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'FREVUEVALIDATING FREIGHT ELECTRIC VEHICLES IN URBAN EUROPE' (FREVUE).

assistant: **Innovation**

Eight of Europe’s largest cities, will demonstrate that electric vehicles operating “last mile” freight movements in urban centres can offer significant and achievable decarbonisation of the European transport system. Demonstrators will be deployed in Amsterdam, Lisbon, London, Madrid, Milan, Oslo, Rotterdam and Stockholm. The demonstrators have been designed to ensure FREVUE covers the breadth of urban freight applications which occur across Europe.By exposing 127 electric vehicles to the day to day rigours of the urban logistics environment, the project will prove that the current generation of large electric vans and trucks can offer a viable alternative to diesel vehicles - particularly when combined with state of the art urban logistics applications, innovative logistics management software, and with well designed local policy.The project will demonstrate solutions to the barriers currently inhibiting uptake of EVs in the sector and includes leading European researchers who will design and then implement a common pan-European assessment framework to understand the impacts of these solutions. This will ensure that the project creates a valuable European evidence base on the role of EVs in urban logistics. Partners will produce a detailed White Paper on the feasibility of EV rollout in logistics across Europe, with chapters containing best practice advice on EV in logistics for: policy makers, logistics operators, their customers and companies developing technology to support the sector.The final overarching objective is to encourage the exploitation of these best practice results through a targeted dissemination campaign aimed at decision makers in the logistics industry. To complement this, FREVUE will also create a network of “Phase 2” cities to directly share the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Impact of MPXV infection on pregnancy outcome and newborn health'.

assistant: **Concept**

Pregnant women have an increased risk of severe mpox disease, however, the underlying mechanisms remain elusive. To better understand altered transmission pattern of MPXV and its impact on this vulnerable population, PREGMPOX aims to assess the extent of MPXV spreading among pregnant women in South Kivu and neighboring regions through both passive and active surveillance. Passive surveillance will utilize existing health data from local facilities, capturing reported cases, while active surveillance will involve direct community engagement to identify and document unreported cases. In sentinel study sites in hot spot areas, the prevalence of MPXV infection among pregnant women will be investigated and potential transmission routes determined. Moreover, our project aims to document and analyze adverse pregnancy outcomes associated with MPXV infection, such as spontaneous losses, stillbirths, preterm deliveries, and neonatal infection. MPXV+ pregnant women will be asked to participate in a cohort study where they will be followed until delivery to document pregnancy outcomes, maternal immune response, and virus abundance and pathological changes in the placenta. This will help to determine specific risk factors and modes and frequencies of vertical transmission to the unborn, and generate a list of clinical and immunological predictors for adverse outcomes for pregnant women and neonates. As a prerequisite to evaluate the safety of the MVA-BN vaccine and tecovirimat treatment in pregnant women, we will create a comprehensive register of adverse pregnancy outcomes, using a pharmacovigilance model to monitor and analyze adverse events following immunization and treatment. The results of our multidisciplinary studies will be crucial for developing guidelines and recommendati
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Probing stresses at the nanoscale' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Summary:I will exploit novel molecules whose fluorescence properties depend strongly on the environment, notably on their spatial confinement, to study local stresses in complex materials down to the nanometer length scale and with unprecedented temporal resolution. Based on successful preliminary tests, I will develop this innovative methodology to tackle the fundamental scientific challenge of quantifying the long-range and very non-linear elasto-plastic stresses that govern the dynamics of friction, the glass transition and rheology.Friction is an immense global source of energy loss; the glass transition is perhaps the most important unsolved problem in condensed matter physics; and rheology in complex fluids is at the same time ubiquitous and poorly understood. The common denominator of these three open challenges is that in each, the material’s macroscopic mechanical behavior results from a complex interplay between microscopic stresses that remain ill characterized. This presents a scientific bottleneck as well as a major obstacle in the engineering of many important materials and tools such as ball bearings, plastics and foodstuffs.The fluorescent environmentally sensitive probes will allow me to achieve breakthrough results in three areas at once: (1) Locally measuring stresses in a frictional contact; (2) Probing the glass transition by local stress and viscosity measurements; (3) Visualizing and quantifying stress transmission in flowing complex fluids to explain non-Newtonian and non-local viscosity effects microscopically. I have a track record in providing new insights in long-standing problems, spurring renewed scientific interest, and in combining fundamental research with potential for technological innovation. By probing local stresses in much more det