RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Sixth Framework proposal on 'HTLV protease: synthesis and inhibition'.

assistant: **Concept**

Human T-cell leukemia virus type 1 (HTLV-I), the first human retrovirus to be discovered, has been shown to be clinically associated with adult T-cell leukemia/lymphoma and tropical spastic paresis/HTLV-I-associated myelopathy. Currently, it is estimated that 15 million to 20 million individuals worldwide are infected with HTLV-I, for which there is no effective treatment, as is the case for adult T-cell leukemia. For the virus to mature and assemble infectious particles, the polyproteins must be processed by retroviral protease. HTLV aspartic protease is thus considered an attractive target for the development of inhibitors to treat HTLV-I infections.However, to date only very few peptide-based inhibitors against HTLV-I protease have been reported. The development of effective inhibitors against HTLV-I protease is thus the major goal of this proposal. The first step will be to synthesize by means of native chemical ligation (NCL)" HTLV-I protease, which is a small dimmer comprising two identical subunits, each containing 125 amino acids. NCL is particularly suitable for the synthesis of large quantities of proteins for biological studies. There will thus be sufficient quantities of material available for the screening process to discover HTLV-I protease inhibitors.The NCL strategy will also be used to prepare proteases with unnatural modifications, which will be used for inhibition studies. New ligation chemistries will also be explored for the synthesis of polypeptides from free cysteine peptides. It is believed that the proposed study will lead to the development of novel inhibitors against HTLV protease, which will, in turn, inspire the synthesis of similar inhibitors against other aspartic proteases involved in a variety of diseases. It is hoped that the tools deve
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Advanced glasses, Composites And Ceramics for High growth Industries' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

The aim of CoACH (Advanced glasses, Composites And Ceramics for High growth Industries) is to offer a multidisciplinary training in the field of high-tech GLASSES, CERAMICS and COMPOSITES based on effective and proven industry-academia cooperation. Our scientific goals are to develop advanced knowledge on glass and ceramic based materials and to develop innovative, cost-competitive, and environmentally acceptable materials and processing technologies. The inter/multi-disciplinary and -sectorial characteristic is guaranteed by the presence of 5 academic partners and 10 companies having top class expertise in glass, ceramic and composite science and technology, modelling, design, characterization and commercialization. Advanced materials fall within the KEY ENABLING TECHNOLOGIES (KETs) and are themselves an emerging supra-disciplinary field; expertise on these new materials brings competitiveness in the strategic thematic areas of: HEALTH-innovative glass and composite for biomedical applications, ENERGY-innovative glass, ceramic and composite materials for energy harvesting/scavenging, solid oxide electrolysis cells and oil, gas and petrochemical industries, ICT-new glass fibre sensors embedded in smart coatings for harsh environment, ENVIRONMENT-new and low cost glass, ceramic and composite materials from waste.The originality of the research programme is to be seen in the supra-disciplinary approach to new glass- and ceramic- based materials and their applications: recruited researchers will benefit from a complete set of equipment and expertise  enabling them to develop advanced knowledge in KETs and strategic thematic areas for the EU and to convert it into products for economic and social benefit. The effective research methodology used by the partners and the mutua
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'NEXT generation civil Tilt Rotor Interactional aerodynamic tail oPtimisation'.

assistant: **Concept**

The aerodynamic configuration definition of the NGCTR needs to be confirmed by a large scale powered wind tunnel experiment, with the aim to verify and confirm the key choices of the configuration and to provide guidelines and proposals for potential additional improvement to be implemented. Within the EU 6th framework programme NICETRIP a 1/5th scale full-span, powered wind tunnel model has been designed and manufactured by NLR and tested in DNW-LLF and ONERA S1, with support of DLR. In order to fully exploit the FP6 research program, NEXTTRIP is a 30 month- 2.77 MEuro valued project based on re-using the existing NICETRIP powered model and key-partners responsible for the successfulexecution of the NICETRIP low speed test.The NEXTTRIP partners, NLR, DNW, DLR, Hit09 & Fokker will work together to modify the NICETRIP model, perform the wind tunnel test in DNW-LLF and define an optimal Empennage configuration based on the wind tunnel test results and given boundaries. NLR will coordinate the NEXTTRIP project and will perform wind tunnel model design and manufacture, test preparations (including GVT), advanced flow visualisation during wind tunnel test and wind tunnel data analysis. DNW will support test preparation and perform the wind tunnel test. DLR will support test preparation and perform data-acquisition and piloting. Multi-objective aerodynamic empennage optimisation will be performed by Hit09 after wind tunnel dataanalysis. Fokker will, together with NLR, perform a verification of compliance with feasibility and industrial constraints during the empennage optimisation process. For all three empennage configurations, both powered and unpowered test will be performed and for a selected configuration advance flow visualisation will be performed for a better understa
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Higgs and Beyond the Standard Model Effective Field Theory, systematic developments.' (HIGGS-BSM-EFT) under Horizon 2020.

assistant: **Objectives**

The focus of this proposal is to systematically develop the Standard Model effective field theory and to use this formalism to study the Higgs boson. The need to engage in this effort is clearly well motivated considering current Large Hadron Collider (LHC) results. Developing the general effective field theory framework to include quantum mechanical corrections is essential if future deviations in Higgs properties are to be systematically studied at high precision in a model independent manner. Higgs properties are currently only roughly known, with large errors. The upcoming data set from LHC will be at least five times as large as the data set gathered in the initial run. Further, the LHC will now be operating at twice the collision energy compared to the initial run. Using this rich data set, Higgs properties will be determined with about an order of magnitude improvement in experimental precision. Resolving more precisely the properties of the Higgs is expected to give evidence for the effects of fundamentally new particles and interactions, involved in stabilizing the Higgs mass against quantum corrections. Utilizing the resources of this grant, calculations of the most important quantum corrections to Higgs production and decay processes in the general effective field theory of the SM will be undertaken. This work builds upon past contributions in this area by the experienced researcher. Phenomenological analyses to refine our knowledge of the Higgs Boson will also be further developed. The final goal that this proposal advances towards is nothing less than to decode, and discover, a more fundamental theory of nature from a pattern of precious clues embedded in future LHC data.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Cell-like Autonomy: An Autonomous Artificial Cell with Self-regulated Oscillation' in the context of a Horizon Europe call.

assistant: **Objectives**

The living cell is an active system that can display autonomy by implementation of dissipative out-of-equilibrium and self-regulated oscillatory behaviours. Manifestation of these dynamic traits into artificial microcompartments (termed artificial cell or protocell) will advance the construction of “smart” artificial cells and the development of synthetic protobiology. Even though numerous reports have illustrated the feasibility of fuel-depleted out-of-equilibrium reactions/behaviors in artificial cells, implementation of more advanced self-regulated artificial cells capable of sustained cell-like dynamics and homeostasis is still very challenging due to the lacks of apparatus and strategy. The overall aim of this proposal is therefore to construct an autonomous artificial cell capable of self-regulated oscillation, which can be coupled to sustained out-of-equilibrium behaviors and environmental homeostasis by chemo-chemical/chemo-mechanical transition modes. Implementation of this proposed work will advance development of synthetic protobiology by producing “smart” protocells with cell-like autonomy. Coupling the self-regulated oscillations to other forms of out-of-equilibrium behaviors by chemo-chemical/chemo-mechanical transitions will further extend the significance of this work by offering a strategy to construct smart and adaptive materials (e.g., autonomous soft robotics) for engineering applications.


**Keywords:** artificial cell, cell-like autonomy, self-regulated oscillation, homeostasis, chemo-chemical, chemo-mechanical signal transition, soft micro-robiotics
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Innovative Microturbine Technology For Delocalised, Off-Grid Electricity Generation' in the context of a Horizon 2020 call.

assistant: **Objectives**

Advanced Microturbines and FAST’s AirWatt project is a Phase 1 winning project from the Horizon 2020 SME Instrument call of June 2014. The project is based on the industrialisation and commercialisation of a patented, miniaturised, integrated turbine and electrical generator, designed to be introduced into the gas supply pipelines, taking advantage of existing pressure drops and gas flow in the system to generate electricity that can be used to power apparatus for the monitoring and control of the pipeline. Our plan is to use our microturbine to power locally smart gas grid solutions, such as monitoring and control remote terminal units (RTUs).Founded in 2013 in Genoa, Italy, as a spin-off of the Italian Institute of Technology, Advanced Microturbines Srl, is a technology-driven micro-enterprise and inventor of the integrated, miniaturised turbine-generator that is the basis for AirWatt. In our mission to develop our innovative idea and bring to the market novel solutions for energy storage and supply system for off-grid applications, we encountered the company FAST SpA, a manufacturer of automation and process control systems based in Reggio Emilia, Italy.With more than 30 years of experience, FAST is one of the leaders in control and supervision systems,  recognised for their state-of-the-art solutions.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fifth Framework proposal for the project 'Localized orbitals for the treatment of dynamical and non-dynamical correlation'.

assistant: **Objectives**

This project covers two principal points. The first point is about a variational method for obtaining localized orbitals. This approach has been recently proposed and implemented in a preliminary way in the Laboratoire de Physique Quantique (LPQ) of Toulouse University. Working with local orbitals induces a hierarchy in the importance of the Slater determinants in a large CI basis. This makes possible to eliminate those determinants whose weight in the CAS wave function is negligible, and to replace therefore the CAS expansion by a (usually much shorter) MR expansion. Part of the work will be to replace the variational approach with a perturbative one, the implementation of a reduced transformation of the two-electron molecular integrals and the possibility of neglecting the interaction between distant regions of the system. A second point is the application of this technique in the calculation of realistic systems covering different fields. In some electronic spectroscopy problem a local approach can produce important results. For example, in excitation processes of a cromophore group in a large molecule with a MR description of the orbitals located in the cromophore region, or in large delocalized biological systems ( e.g., the pi/pi* excitation in retinal). It is crucial to test the sensitivity of local approaches to far substituents shifts. In the study of the mixed-valence and magnetic systems the local descriptions are easier to interpret in accord to magnetic hamiltonians so that both the exchange and Coulomb parameters will be easier to get.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Halophyte Biorefinery Process for Sustainable Production of Textiles, Composites, and High-Value Biochemicals' (HALO-TEX), addressing dissemination and exploitation.

assistant: **Impact**

HALO-TEX demonstrates a novel, sustainable, and circular bioproduct manufacturing system based on the biorefinery of salt-tolerant plant biomass. Cellulose-based yarns and fabrics with improved recyclability, bio-based additives, and composites are targeted towards high-pressure textile and biochemical industries. It addresses the European Green Deal objectives, the EU Circular Economy Action Plan, and the EU strategies regarding bioeconomy and circular textiles, amongst other policies and initiatives. HALO-TEX goes beyond the state-of-the-art by using underexploited feedstock in an innovative extraction, pretreatment, and separation process cascade for maximum resource valorization, and sustainable cost-effective manufacturing of multiple products. Consumer acceptance studies and comprehensive product information systems will be developed to overcome the social barriers related to the uptake of bioproducts. The textile industry has a tremendous negative environmental impact regarding primary raw material, freshwater and land use, emissions and pollution, and waste generation. HALO-TEX addresses these issues by using novel, secondary feedstocks grown in marginal land, developing circular biorefinery system with low energy and chemical input, and enhancing the sorting and recycling of materials and bioproducts. It will provide an innovative value chain and a sustainable model for bioproduct manufacturing to advance transitions towards a circular bioeconomy, increase the uptake of novel products, and foster socio-economic opportunities, especially in rural, vulnerable regions. The partners are skilled experts within their respective fields, and the project builds on previous Horizon projects. Located across Europe, the consortium provides a broad perspective on the relate
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Broken symmetries in relativistic quantum chemistry', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

BRUNCH is a fundamental project that will provide an entirely new theoretical framework and develop an ambitious methodological toolbox to tackle the current challenges of molecular magnetism. f-ions-based molecular magnets and subsequent multifunctional materials are on the way to offering the building blocks for tomorrow's technologies, such as quantum computing and spintronics. Most of their appealing features originate from relativistic effects, which are huge in lanthanide and actinide-based complexes. Whilst theoretical chemistry is known to have provided a critical understanding of magnetic phenomena, it faces the reality of increasing complexity in terms of the size and diversity of the physicochemical properties of interest. BRUNCH aims to make density functional theory (DFT) a new standard in molecular magnetism, offering unprecedented access to the computation of magnetic and luminescence properties. Despite its hegemony in chemistry, DFT cannot properly describe magnetic systems, and their study relies on exploiting spin symmetries to bypass the issue. However, in the presence of relativistic effects, the notion of spin and the associated symmetries become irrelevant. The key idea of BRUNCH is to develop a theoretical framework based on symmetries specifically adapted to the relativistic context: time-reversal and symmetries associated with the total angular momentum. This will enable the implementation of a methodological toolbox in relativistic quantum chemistry. It includes novel DFT methodologies able to accurately/quantitatively assess magnetic interactions and luminescence properties. BRUNCH will allow addressing critical issues at the heart of molecular magnetism, e.g. decoherence phenomena or the magneto-electric effect. By doing so, BRUNCH aims to r
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Mapping the NANOtechnology innovation system of RUssia for preparing future Cooperations between the EU and Russia', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

The EU is interested in obtaining a survey of main Russian research infrastructures active in nanotechnology and nano-structured materials as a basis for initiating future cooperations between the EU and Russia. In the NANORUCER activity two leading organization from the EU and Russia in the fields of innovation research and nantoechnology join forces to deliver this aim. Based on a performance analysis using bibliometrics and patent statistics and a careful in depth mapping of nanotechnology and nano-strucutured materials research activities in Russia, a strengths and weaknesses analysis of the Russian nanotechnology innovation system will be made. A systematic comparison with respective EU R&D activities in nanotechnology and nano-structured materials will allow identifying opportunities for future cooperations between the EU and Russia. These will be specified by thematic fields in order to detect areas of common interests with most benefits for cooperating partners. Involving Russian and EU stakeholders during workshops, recommendations for supporting such cooperations between the EU and Russia will be developed, and concrete actions proposed. A particular strength of the proposed support action is that it can build on a broad experience of both participants in analysing nanotechnology innovation systems. In previous projects the Russian partner has already developed databases of R&D organizations providing research on nanoscale and its staffs provided the expertise for the National Program of Infrastructure Development for Nanotechnology. In addition the participants will mobilize the in depth knowledge of their mother organizations, the Fraunhofer Society and in particular the Fraunhofer Alliance Nanotechnology, and the Russian Academy of Sciences, in nantotechnol