RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'High-Performance Millimeter-Wave and Terahertz Components Based on Spoof Surface Plasmon Polaritons for Next-Generation Communications' under Horizon Europe.

assistant: **Concept**

The millimeter-wave (mmWave) and THz frequency bands hold immense potential for enabling ultra-fast data transmission and unlocking unprecedented bandwidth capabilities, but the RF components and circuits at these high frequencies suffer from relatively-large insertion losses and manufacturing difficulty/inaccuracy. Therefore, this entails researching into a fully-new type of transmission lines able to mitigate the high insertion losses and alleviate fabrication-tolerance issues of RF components. This MITCOM project aims to explore and develop new spoof surface plasmon polariton (SSPP) transmission lines for the design of mmWave and THz components with low insertion losses and their applications in next-generation wireless communications. Specifically, the overarching aim is to obtain SSPP-based mmWave and THz bandpass filters and multiplexers with low losses, low interference, high fabrication tolerance, ease of manufacturing and integration. Firstly, a new type of planar half-spaced SSPP transmission lines for waveguide and on-chip application scenarios will be proposed, and their design methodology will be developed to balance loss, ease of manufacturing and crosstalk issues, serving for E-plane waveguide and on-chip filter design. Then, the strategy for different filter specifications and tolerance levels will be analyzed in the steps of modeling and implementation through particular manufacturing technologies. Based on the design methodology and strategy, a series of E-plane waveguide and on-chip filters will be manufactured for validation and industry applications. Finally, based on the newly-conceived planar half-spaced SSPPs, diplexers and triplexers will be also designed, characterized and fabricated. The outcomes of the MITCOM project will contribute to the re
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Investigation of the functional propreties of NMDA receptors containing more than one type of NR2 subunit and the functional stoichiometry of the high-affinity Zn² binding site.' (2002-2006).

assistant: **Concept**

NMDA receptors (Nadirs) are implicated in many neuropsychological and neuropath logical processes including schema, epilepsy and schizophrenia. They are heteromeric gated-gated ion channels likely composed of two NR1 and two NR2 subunits. Extra cellular agents including Zn. Co-released at some synapses with glutamate modulate nadirs, Zn is a potentially important physiological regulator of Malfunction. The NR2 subunit subtype, NR2A being the most sensitive, determines Zn affinity for Nadirs. InNR2A the high-affinity Zn binding site maps to the N-terminal domain, whilst in NR2B the homologous domain binds the neuroprotectant ifenprodil, a non-competitive antagonist specific for NR2B-containing NMDARs. Demodulator N-terminal domains therefore present potentially interesting pharmaceutical targets. To date, functional studies on recombinant Nadirs have centred on receptors containing only one NR2 subunit subtype, however, biochemical evidence suggests that many native Nadirs contain two subtypes of NR2.Using mutated receptors we will isolate populations of recombinant triplet" receptors containing two different subtypes of NR2. Their function will be assessed using electrophysiological techniques, allowing us to answer several key questions. Firstly, "triplets" containing a wild-type NR2A subunit and a NR2A subunit lacking the functional high-affinity Zn binding site will be used to determine the functional stoichiometry of the Zn inhibition. Secondly, using "triplets" containing both a NR2A and a NR2B, NR2C or NR2D subunit, we will assess the functional properties of recombinant Nadirs containing two types of NR2 subunit. Of particular interest is the interaction in NR2A/NR2B "triplets" between Zn and ifenprodil. Finally, to assess the physiological relevance of triplet"
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'FLexible Architecture for \nVirtualizable wireless future Internet Access' (FLAVIA) under Seventh Framework.

assistant: **Objectives**

Wireless networks importance for the Future Internet is raising at a fast pace as mobile devices increasingly become its entry point. However, today's wireless networks are unable to rapidly adapt to evolving contexts and service needs due to their rigid architectural design.We believe that the wireless Internet's inability to keep up with innovation directly stems from its reliance on the traditional layer-based Internet abstraction. Especially, the Link Layer interface appears way too abstracted from the actual wireless access and coordination needs. FLAVIA fosters a paradigm shift towards the Future Wireless Internet: from pre-designed link services to programmable link processors. The key concept is to expose flexible programmable interfaces enabling service customization and performance optimization through software-based exploitation of low-level operations and control primitives, e.g., transmission timing, frame customization and processing, spectrum and channel management, power control, etc.FLAVIA's approach is based on three main pillars: i) lower the interface between hardware-dependent layers and upper layers, ii) apply a hierarchical decomposition of the MAC/PHY layer functionalities, and iii) open programmable interfaces at different abstraction levels. To prove the viability of this new architectural vision, FLAVIA will prototype its concept on two wireless technologies currently available, 802.11 and 802.16, representing today's two main radio resource allocation philosophies: contention-based and scheduled. Moreover, FLAVIA will assess the applicability of the proposed architecture concepts to the emerging 3GPP standards.FLAVIA's concept will allow boosting innovation and reducing the cost of network upgrades. Operators, manufacturers, network designers
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Ultracold YbF molecules to measure the electron's electric dipole moment.' (UCEEDM).

assistant: **Concept**

The project aims to show that the electron's electric dipole moment (eEDM) could be measured with an unprecedented precision of 10^{-31} e cm by using ultracold polar molecules. Such a measurement would be a demanding test of theories beyond the Standard Model of particle physics, and a search for the undiscovered forces responsible for the observed asymmetry between matter and anti-matter in the Universe. The key advance that will unlock this extraordinary sensitivity is interferometry with molecules cooled to ultracold temperature. I will make an intense, slow-moving beam of YbF molecules, which are known to be exceptionally sensitive to the eEDM. I will then apply laser cooling in both transverse directions to bring the temperature below 50 microkelvin, yielding a highly-collimated molecular beam. Next, I will build a spin interferometer using these ultracold molecules. Finally, by paying careful attention to noise sources, especially magnetic field noise, I will show that the interferometer can reach the sensitivity set by the quantum projection noise. Laser cooling of molecules is a new technique, and I will be the first to use it to enhance the sensitivity of a measurement that tests fundamental physics.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Forest research environment in umea' (FORE) targeting Fifth Framework.

assistant: **Abstract**

Fore is a joint facility provided by the two universities in Umeaa, which are located on the same campus and has well-established and extensive research links. FORE will provide basis for research in forestry and forestry-related research: plant physiology, forest biotechnology, molecular biology and genetics, wood and fibre research, plant pathogen interaction, plant animal interaction, ecophysiology, forest management, remote sensing for forestry and impacts on forest ecosystems of climate change. The FORE infrastructure provides a unique combination of well-equipped laboratory facilities, experimental forests, a variety of experimental plots, biological archives, and extensive databases from long-term inventories. FORE is a unique cluster of leading edge expertise and offers 36 IHP visitors 739 days access over two years to laboratories and experimental facilities equipped to high state-of-the art" standards for research in forestry and forestry related fields.Application:Applications can be submitted twice a year by e-mail, fax or mail. The application form and the procedure for applying are described on the FORE Home Page http://www.fore.se.Project Manager:Anders Ericsson, SLU, Institutionen for Skoglig Genetik och Växtfysiologi (Dept of Forest Genetics & Plant Physiology), SE-901 83 Umea, SwedenTel: 090-7865730 (int. +46-90-786 5730)Fax: +46-90-7865901E-mail: Anders.Ericsson@genfys.slu.se"
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Sixth Framework proposal on 'INNO-views - innovation policy workshops'.

assistant: **Innovation**

The INNO-Views module is a follow up of the TrendChart workshops contract managed by Technopolis BV, which will end in February 2007. DG Enterprise and Industry now aims at further development of the existing tools and their integration in a consistent strategy, in accordance with the new Integrated Action Plan on Innovation and Research launched at the end of 2005.In the framework of Europe INNOVA and PRO INNO Europe, the overall role of the present INNO-Views project in this regard will be to bridge the gaps between innovation policy analysis, policy learning and dissemination and transfer of good practices in innovation policy, following the lines of the Open Method of Coordination". It is the objective of this INNO-Views project to continue the process of the TrendChart Workshops with the organisation of four workshops per year to explore new and emerging innovation themes.In view of the role within the PRO INNO Europe initiative, the project will, however, adopt a more forthcoming approach, and will notably contribute to the identification of promising innovation policies to be further discussed and disseminated under the INNO-Learning Platform module."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Clinical validation and commercialization of innovative immunostimulating Interstitial Laser Thermotherapy' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

The INTHER project will bring the groundbreaking immunostimulating Interstitial Laser Thermotherapy (imILTCLS) to the market and clinical practice. This minimally invasive therapy is designed to achieve local tumour destruction and stimulate specific antitumour immunity in a patient’s body. In recent years, anti-cancer therapies based on activation of the immune system have grown in significance and popularity. This approach is especially viable for patients who previously had very few treatment options. However, only approx. 20 % of all patients respond to drug-based immunotherapies of today. The key need of medical oncologists is to increase those response rates and thus decrease cancer-related suffering, increase life expectancy and survival rates for the patients. The project will meet those needs by delivering a novel device-based cancer immunotherapy method that destroys the tumour locally and induces long-lasting, vaccination-like, systemic immunity against the treated form of cancer. As the world’s first device-based laser immunotherapy, imILTCLS will curve its own market niche on the fast growing Cancer Immunotherapy Market and therefore have a significant disruptive effect on this market. The studies performed to date have confirmed the therapeutic capability of the new method. In the project, the method will be further validated for the two chosen solid tumour types: pancreatic cancer and breast cancer. This will enable CLS to shorten the time to full commercialisation, obtain the clinical acceptance and fully exploit the commercial potential of the new treatment method. The clinical uptake of imILTCLS in Europe will lead to reduction of costs associated with the treatment of solid tumours, especially surgeries, and reduction of costs related to the activatio
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Local vs Global Properties of Large Discrete Structures' (LocalGlobal) targeting Horizon 2020.

assistant: **Abstract**

The PI proposes to study a variety of open problems in extremal combinatorics, an area that deals with the asymptotic relations between various parameters of large discrete structures. This area has grown tremendously in the past few decades, in depth and in breadth, and supplied many spectacular results that affected various other areas of mathematics, such as number theory, group theory, probability theory, information theory and theoretical computer science.A common theme in many of the problems the PI will investigate is the relation between local and global properties of various discrete structures. For example, suppose a graph contains few copies of some fixed graph; what can one infer from this simple local restriction about other more global properties of this object? Perhaps surprisingly, many of the outstanding open problems in extremal combinatorics can be cast in this manner. One such problem is the celebrated hypergraph removal lemma. An important goal of this project is to obtain the first primitive recursive bounds for this fundamental problem. Another family of such problems are motivated by questions in theoretical computer science and ask to develop fast algorithms for deciding if a discrete structure satisfies some predetermined property. The PI will develop a unifying theory for such problems using various combinatorial tools introduced in the past few years. Another set of problems ask to establish that hypergraphs excluding certain types of sub-structures, possess surprisingly good Ramsey-type properties.The common thread going through the above problems is Szemeredi's regularity lemma, which is one of the most powerful tools in extremal combinatorics. An important goal of this project is to find new applications of the graph and hypergraph version
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Assembly Lines In CIrculAtion – smart digital tools for the sustainable, human-centric and resilient use of production resources' (ALICIA) targeting Horizon Europe.

assistant: **Abstract**

A large part of production assets such as robotic arms, conveyor belts do not reach their maximal lifetime and become prematurely obsolescent. Anecdotal evidence from the automotive industry suggests that 60% to 70% of production resources is prematurely taken out of operation, scrapped, or at best sold for spare parts.The aim of ALICIA is to create and demonstrate a Circular Manufacturing Ecosystem (CME) for production resources, such as robotic arms or conveyor belts. The underlaying vision is that within five to ten years, production resources will be traded and reused to their maximum utility in-between factories in Europe, ultimately contributing to “closing the loop” of production assets as circular economy subjects.The project aim will be achieved by integrating and demonstrating in two real industrial environments (at Continental and Comau) a combination of innovative and symbiotic digital tools as key enabling technologies behind the ALICIA CME, ultimately enabling to design, deploy, run, decommission and re-circulate second-hand production lines 40% faster, reduce material consumption by up to 80% and reuse up to 100% of the assets. The innovations behind ALICIA include a machine-readable ontology for mapping factory owner requirements, an AI-matchmaking engine for combining incumbent factory assets with second-hand assets coming from the ALICIA online marketplace, a Plug & Produce middleware for seamlessly connecting the production assets and a Digital Shadow/Digital Twin to ramp-up and operate the ALICIA second-hand line. Novel Circularity-as-a-Service business models will be evaluated.ALICIA addresses the EU “machinery and equipment” as well as “machinery repair service” market segments, which together contributed 288 Billion EUR in value added to the EU ec
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Sixth Framework proposal for the project 'Structured illumination in optical Tomography'.

assistant: **Objectives**

Optical imaging techniques and probe development have boosted knowledge on genomics and proteomics. High quality imaging techniques and novel sources of contrast are being developed, however 3D information and more importantly quantification is still lacking especially at a resolution higher than that provided by confocal microscopy. It is now high time to develop more elaborate approaches that will improve resolution, sensitivity and specificity of real-time in-vivo imaging of gene expression and biological processes in 3D.We propose to develop a novel microscopy technique based on tomographic approaches for 3D in-vivo imaging of biological processes. Optical tomography provides isotropic optical resolution in all three dimensions of space; this resolution is however limited by diffraction to about 250nm for visible light. To overcome this impasse, structured illumination will be implemented, thus improving the resolution drastically compared to conventional microscopy techniques. By making use of saturate d patterned fluorescence excitation, the resolution barrier can be overcome altogether.This technique will be applied to imaging structure and dynamics at the cell nuclear level. Subsequently its potential has to be tested in the analysis of complex systems such as the drosophila melanogaster. To that end, a custom-made microscope will be extended for structured and saturated fluorescence excitation, and corresponding inverse mapping algorithms will be developed to reconstruct the objects or the fluorescence dye distribution respectively from the 3D images. This new optical imaging device will then be used to quantitatively study nuclear and sub-cellular structure, organisation and dynamics in 3D.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'An Integrated Heart Model for the simulation of the cardiac function' in the context of a Horizon 2020 call.

assistant: **Objectives**

The goal of this project is to construct, mathematically analyze, numerically approximate, computationally solve, and validate on clinically relevant cases a mathematically-based integrated heart model (IHM) for the human cardiac function. The IHM comprises several core cardiac models – electrophysiology, solid and fluid mechanics, microscopic cellular force generation, and valve dynamics – which are then coupled and finally embedded into the systemic and pulmonary blood circulations. It is a multiscale system of Partial Differential Equations (PDEs) and Ordinary Differential Equations (ODEs) featuring multiphysics interactions among the core models.The physical and mathematical properties of each core model and those of the even more complex integrated heart model (IHM) will be analyzed. The numerical approximation of IHM develops along several steps: introduce new high order methods for the core models, carry out their stability and convergence analysis, devise new paradigms for their numerical coupling, and construct optimal, scalable, and adaptive preconditioners for the efficient solution of the resulting large-scale discrete problems. To address data variability in clinically relevant cases, new reduced order models and efficient computational techniques will be developed also for forward and inverse uncertainty quantification problems. Two software libraries, LifeHEART and RedHEART, will be built and made available to the scientific community.The project is original, very ambitious, mathematically inspired and rigorous, tremendously challenging, and groundbreaking. If successful, it will provide researchers from applied mathematics and life sciences, cardiologists, and cardiac surgeons with a powerful tool for both the qualitative and quantitative study of cardia