RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Sixth Framework proposal for the project 'Psychological network support to violence traumatized children: disasters, conflicts'.

assistant: **Objectives**

The objectives of the project are to conceive, to carry out and to have the experience of a euro Mediterranean network for the consultation and help when intervening to give medico psychological help to children traumatized by violence during disasters or wars. In each country there already exists specialised teams for the early intervention and for the follow up of traumatized children. But in this area which is still underdeveloped, scientific knowledge and action doctrines are only at their beginnings. T he knowledge and experience acquired by the best experts in each country are not sufficiently made known outside the boarders. Also, the inside teams cannot respond to urgent needs when a major catastrophe occurs. The idea is to create a euro Mediterranean network linking the specialized teams of each nation in order to confront the knowledge and the experience to improve scientific knowledge about psycho-traumatology of the child, "harmonised action doctrines in the fields in the three phases : immediate post immediate and the consequences "elaborate a common handbook for teaching and practice of medico-psychological support to traumatised children, "start up a country by country help system whereby in case of a major catastrophe, help can be requested fro m other countries to evaluate needs and to send reinforcement teams, "taking in account the differential cultural values, and emphasise gender and ethical issue. On a practical level, each of the nine countries within the network will have on a national sc ale a first network linking several intervention and child psycho-traumatology consultation centres. If possible, standardized computer technology will allow communication between several country simultaneously. Meetings and workshops will be organised wit hin t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Climate Information Platform for Copernicus (CLIPC)' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

CLIPC will provide access to climate information of direct relevance to a wide variety of users, from scientists to policy makers and private sector decision makers. Information will include data from satellite and in-situ observations, climate models and re-analyses, transformed data products to enable impacts assessments and climate change impact indicators. The platform will complement existing Copernicus pre-operational components, but will focus on datasets which provide information on climate variability on decadal to centennial time scales from observed and projected climate change impacts in Europe, and will provide a toolbox to generate, compare and rank key indicators. Expanding climate data volumes will be supported with a distributed, scalable system, based on international standards. Guidance information on the quality and limitations of all data products will be provided. An on-going user consultation process will feed back into all the products developed within the project. The “one-stop-shop” platform will allow users to find answers to their questions related to climate and climate impacts data, and to ensure that the providence of science and policy relevant data products is thoroughly documented. Clarity of provenance will be supported by providing access to intermediate data products. Documentation will include information on the technical quality of data, on metrics related to scientific quality, and on uncertainties in and limitations of the data. A climate impacts toolkit will provide documentation on methods and data sources used to generate climate impact indicators. The toolkit will be made available for integration with Climate-ADAPT. The CLIPC consortium brings together the key institutions in Europe working on developing and making available
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'GIs and ‘Segnorine’: an Entangled History of Post-war Sex Work (1943-1954)', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

This project is the first attempt to carry out a systematic investigation of illegal sex work in a European country during the Allied occupation, from a perspective of cultural and transnational history. Focusing on the relations between American soldiers (GIs) and Italian prostitutes (the so-called ‘segnorine’) in 1943-1954, up to the settlement of the Trieste question, the research intends to analyze these women’s experience as the image of the cultural encounters and interconnections between US and Italian societies during the post-WWII transition.In Italy, the Allies forbade any relationship between ‘foreign’ GIs and local prostitutes. The growth of an illegal sex market was one of the consequences of this decision. What emerges is that the ‘segnorine’ were treated as a great danger and were often victims of violence especially because of their sexual relations with African Americans. I argue that they played a key-role in the process of national re-building, a role that has not been thoroughly investigated by scholars.The project addresses three core issues:(1) The intertwining of genderization and racialization in the years of post-fascist democracy;(2) The transcontinental circulation of ideas and models, with particular attention to the inter-crossing of sexist and racist discrimination (e.g., postcolonial and segregationist stereotypes);(3) Imaginary frontiers and collective identities. How did Americans look at Italians, and Italian women? How did Italians look at their ‘conquerors’?I will carry out an extensive review of archival and press sources, also pertaining to pop culture. I will conduct personal interviews too. UNIPI and Fordham University are a perfect match for my project, that will result in three journal articles, a book, and a number of training
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Conflict, Competition, Cooperation and Complexity: Using Evolutionary Game Theory to model realistic populations' (FourCmodelling), addressing dissemination and exploitation.

assistant: **Impact**

Real animals and human populations are complex, involving structural relationships depending upon space and time and varied interactions between potentially many individuals. Human societies feature family units, communities, companies and nations. Some animal also have complex societies, such as primate groups and social insect colonies. Single organisms themselves can be thought of as complex ecosystems, host to many interacting life forms. Models of populations are necessarily idealised, and most involve either simple pairwise interactions or ""well-mixed"" structureless populations, or both. In this project we shall develop game-theoretical models, both general and focused on specific real population scenarios, which incorporate population structure and within population interactions which are both complex in character. We will focus on the themes of Conflict, Competition, Cooperation and Complexity inherent in the majority of real populations. There will be four complementary subprojects within the overall project. The first will focus on developing a general theory of modelling multiplayer evolutionary games in structured populations, and will feed into each of the other three subprojects. The second will consider complex foraging games, in particular games under time constraints and involving sequential decisions relating to patch choice. The third will involve developing computational models of spatio-temporal dynamics for the modelling of pandemics. The final subproject will model cancer as a complex adaptive system, where a population of tumour, normal and immune cells evolve within a human ecosystem.The four subprojects will be developed in parallel fostered by frequent research visits and interactions, each involving a team comprising of EU and North America
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Water and glycerol channels of the MIP family: structure, function, regulation and exploitation' (1994-1998) targeting Fourth Framework.

assistant: **Abstract**

Recently a family of presently more than 100 membrane channel proteins has been described: the Major Intrinsic Protein or MIP family. MIP channels are crucial for water and/or solute transport across biological membranes in humans, animals, plants, fungi and bacteria. Water channels of the MIP family - termed aquaporins - are essential for the regulation of human water balance. Dysregulation or dysfunction of aquaporins is associated with kidney, eye, heart, and liver diseases, and aquaporins are potentially important targets for pharmacological and cosmeceutical application. In plants more than 20 aquaporins have been identified in a single species. They are believed to be crucial for plant water homeostasis and hence are potential targets for the genetic engineering of crop tolerance to limited water availability. Most microbial MIP channels transport small polyols in nutrition and osmoregulation and they constitute a major potential for the engineering of metabolism towards the production of useful chemicals from renewable resources. European laboratories, incorporated in this application, have contributed to pioneering research into MIP channel proteins. In this programme we bring together leading European research and industrial laboratories, to work towards the understanding of the structure-function relationship and the physiological role of MIP channels in humans, animals, plants and micro-organisms. The objective is to establish the scientific basis to unlock the full exploitation potential of this unique protein family. To achieve this we will: - Develop and optimise techniques for the production, purification and structure-function analysis of membrane proteins, especially MIP channels. - Determine the molecular structure of six MIP channels in order to defin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on '2D Material-based Non Volatile-PHotOnic Synapsis for ultra-low Energy Neural networks'.

assistant: **Concept**

Neuromorphic computing is expected to have a transformative impact by exploiting the brain like computations. During the last two decades, Neuromorphic computing has been implemented on electronics, with the most important circuit element capable of best mimicking neurons and synapses that is the memristor. Yet, constructing a highly interconnected networks of memristors to resemble biological architecture requires metal wires with extremely scaled area that results in an immense heat generation and power consumption, hindering the neuromorphic electronics development. Recently the new field of neuromorphic photonics has attracted a lot of interest as a valid alternative. In neuromorphic photonics the network connections are made of optical waveguide that provides inherent parallelism, ultra low latency, and almost zero power dissipation. However neuromorphic photonic will only meet its expectation as a groundbreaking technology when an Ideal photonic memristor is available. The ideal photonic memristor (currently missing) should adjust the amplitude of transmitted light in a non-volatile and analog manner, not via light absorption but through light phase change, to minimize the synapsis insertion losses. In this project I will demonstrate the low loss photonic memristor by innovative exploitation of energy band alignment and refractive index modulation of 2-Dimensional (2D) material heterostructures. I will embed the 2D heterostructure within a photonic integrated Mach- Zehnder Interferometer to showcase the non-volatile optical phase shifting with 1-10 fJ energy consumption per bit. This project will conduct interdisciplinary research across light-matter interaction, that requires contributions from materials science, physics, photonics and electronics. Positive outco
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Dark-Soliton Engineering in Microresonator Frequency Combs' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

The continuing increase in Internet data traffic is pushing the capacity of single-mode fiber to its fundamental limits. Space division multiplexing (SDM) offers the only remaining physical degree of freedom – the space dimension in the transmission channel – to substantially increase the capacity in lightwave communication systems.The microresonator comb is an emerging technology platform that enables the generation of an optical frequency comb in a micrometer-scale cavity. Its compact size and compatibility with established semiconductor fabrication techniques promises to revolutionize the fields of frequency synthesis and metrology, and create new mass-market applications.I envision significant scaling advantages in future fiber-optic communications by merging SDM with microresonator frequency combs. One major obstacle to overcome here is the poor conversion efficiency that can be fundamentally obtained using the most stable and broadest combs generated in microresonators today. I propose to look into the generation of dark, as opposed to bright, temporal solitons in linearly coupled microresonators. The goal is to achieve reliable microresonator combs with exceptionally high power conversion efficiency, resulting in optimal characteristics for SDM applications. The scientific and technological possibilities of this achievement promise significant impact beyond the realm of fiber-optic communications.My broad international experience, unique background in fiber communications, photonic waveguides and ultrafast photonics, the preliminary results of my group and the available infrastructure at my university place me in an outstanding position to pioneer this new direction of research.


**Keywords:** Fiber-Optic communications, Optical frequency comb technology,  micro
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Composite mould tool based on 3D printing'.

assistant: **Objectives**

COMBO3D proposes to additively manufacture a short fibre reinforced thermoplastic tool with integrated active temperature control, to shorten the cure cycle time and so to focus on the objectives addressing the limitations and implementing the improvements of the state of the art project. By using a robot guided large scale short fibre reinforced plastics extrusion additive manufacturing process the tool can be produced as a single part, directly integrating the temperature control, shortening the lead-time and enabling simple and fast restoration of the tool surface to compensate for the expected lower lifespan. Using a robot-guided process also allows to print the final demonstrator tool in one piece in curved layers (real 3D printing). To ensure tool stability during the curing cycle, short carbon fibre reinforced semi-crystalline high performance thermoplastic PAEK will be used. Commercially available PAEK have a form stability of over 250°C in unreinforced grades and CF filled grades are available with heat deflection temperatures of 315°C and more.By introducing heating elements in the tool, it can conduct heat to the parts lower surface, in combination with the autoclave or oven, heating it up from both sides. These heating elements can be electrical or fluid channels connected to an external temperature control. Electric heating elements provide higher heat up rates but fluid heating allows to change from heating to cooling mode and hence to also cool the tool. Thereby it is possible to also achieve faster cool down. COMBO3D therefore proposes to use both heating elements in the tool.The whole development of the printed tool is supported by simulation. The design of the tool will be optimized by implementing the heating and cooling system in a thermal simulation
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Leveraging the impact of gut microbes to advance the efficacy of CAR-T cell immunotherapy.' to be submitted under Horizon Europe.

assistant: **Abstract**

T cell therapy with chimeric antigen receptor (CAR)-T cells is a curative-intent, transformative treatment aimed to boost antitumor abilities of host T cells against refractory/relapsed B cell malignancies and, recently, against refractory/relapsed myeloma. Major challenges of current CAR-T cell immunotherapies are the loss of long-term efficacy, the occurrence of toxicities including infections, and a lack of personalized patient strategies including biomarkers for response prediction and interventions to enhance CAR-T cell efficacy. This proposal builds on our first evidence for a major role of the gut microbiome in CAR-T cell therapy, and addresses these challenges by presenting a translational research strategy aimed to dissect and leverage the impact of gut microbes in its antitumor efficacy.In Aim 1, we will investigate the hypothesis that gut and intratumoral microbiome configurations and its metabolites are associated with clinical response of CD19-CAR-T cells in lymphoma, with immunophenotypes of these engineered T cells and the tumor immune microenvironment. We will examine the effects of nutrition and antimicrobial drugs on microbiome features to identify potential mechanisms and therapeutic levers. In Aim 2, we will address the biology of microbiome-CAR-T cell interactions through experimental gut microbiome modulations, and humanizing mice with patient-derived microbial ecologies and individual species and strains in preclinical research models. In Aim 3, we will assess potential therapeutic interventions to increase CAR-T efficacy by investigating the action of microbiome-derived metabolites on CAR-T cells and studying phage- and diet-based interventions to mitigate antibiotic-induced gut microbiome dysbiosis.Characterising the function of the microbiome a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Development and Utilization of a Complete Directional Borehole Radar System with a Maximum Operating Depth of 2500 Meters' in the context of a Fourth Framework call.

assistant: **Objectives**

There is a strong need in all branches of applied earth sciences for an exploration tool able to investigate the structure and characteristics of rockmasses around boreholes within a radius of several hundreds of meters. Directional borehole radar is presently the most promising technique in this field because it gives a true 3D information. Although various instruments have been developed, the RAMAC directional borehole radar system, manufactured by Malaa Geoscience (Sweden) is presently the only equipment available worldwide for general applications. There are however several limitations, inherent to the present design, which result in restricted operating depth (max. 1000-1500 m), slow data acquisition, uncertain directional interpretation in some circumstances, and high operating costs. The main technical objective of the proposed research is to develop a new borehole radar system in order to overcome these limitations. It would consist of a directionalmodule for deep operation (2500 m in this project, expandable to greater depth in a further stage), working on a standard logging cable and of a module for fast data acquisition mainly dedicated to shallow tomographic use. An efficient and environmentally friendly fluid exchange procedure in deep boreholes, necessary in order to carry out radar surveys, will be developed and tested for the exploration of salt deposits around gas storage caverns. Sofware developments, including diffraction tomography, and laboratory measurements of dielectrical characteristics of rock samples will also be carried out in order to improve the quality of the geophysical and geological interpretations. The industrial objective is not only the design of the new intrument, but also the expansion of the application range of the method, thus i