RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Human interactions with the mountain birch forest ecosystem: implications for sustainable development' goes beyond current state-of-the-art under Fifth Framework.

assistant: **Innovation**

In the worldwide attempt to reduce dietary saturated fat intake, carbohydrates may provide a suitable alternative. The aims of this project are to characterise the metabolic quality" of various carbohydrates, with the main focus on starch and lactose. With 13C stable isotope techniques, 13C-glucose response to various carbohydrate sources will be studied, including parameters that could modulate this response such as gastric emptying/ intestinal transit and digestion rates. A variety of products (including breakfast food and baby food will be developed and evaluated. Use of animal models will produce additional parameters to define starch-containing products, suitable for diabetics or for people at risk to diabetes and obesity. These products will be then tested in relevant target populations. Fermentation of carbohydrates (13C starch and 13C lactose) in man will be characterised to develop low fat dairy products for lactose intolerant persons."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Vascular Control of NASH Progression' in the context of a Horizon Europe call.

assistant: **Objectives**

Non-alcoholic steato-hepatitis (NASH) is a major risk factor for hepatocellular carcinoma (HCC), the 6th most common cause of cancer-related death worldwide. The transition among different NASH stages to HCC stems from the complex interaction of multiple factors, including gut-liver axis modifications and a progressive dis-architecture of the liver parenchyma.The central role of endothelial cells in regulating the metabolic crosstalk along the gut-liver axis and in shaping the spatial organization of the liver parenchyma suggests a potential vascular control of NASH progression. However, the possibility to precisely define the endothelial contribution is restrained by the limited ability to correlate gene expression profiling and functional readout, such as protein phosphorylation, with the complex morphological modifications occurring during NASH.To overcome these limitations, we combined innovative “spatial sorting” strategies with transcriptomics and quantitative phosphoproteomics, providing the first draft of the anatomical organization of proteins signaling in the liver vasculature. Moreover, we unambiguously identified tyrosine phosphorylation – the main target of the anti-angiogenic therapy (ATT) – as one of the most spatially regulated signaling event.Building on this expertise, we will combine spatial sorting strategies in gut and liver with mouse models of NASH progression and advanced imaging modalities to pursue the following aims:1. Provide a spatiotemporal characterization of the gut and liver vasculature undergoing NASH development.2. Dissect the vascular determinants of NASH progression.3. Identify the molecular mechanisms underlying the synergistic effect between AAT and immune checkpoint    inhibition.Together, our results will lay the foundation for u
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'The effects of spatial attention on stimulus encoding in rat barrel cortex and on relationships between barrel cortex and locus coeruleus norepinephrine neuron spiking' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

Norepinephrine (NE) medications affect attention and the ability to ignore distracting stimuli. Current theories focus on prefrontal cortex (PFC) as the site of NE-induced modulation. Sensory cortex neurons are also affected by NE. We propose testing the hypothesis that NE may actually affect attention via direct action in sensory cortex. To test this hypothesis, we will develop a rat spatial attention task that is analogous to those used in the nonhuman primate. Head-fixed rats will be presented with a train of whisker deflection stimuli on both sides of the face and will have to report detection of the reward-predicting stimulus in a train of distractors via operant response. On alternating trial blocks, cues will direct spatial attention to a whisker on one or the other side of the face. We will then perform concurrent extracellular recordings from barrel cortex neurons, which respond selectively to whisker deflections on one side of the face, but not the other. We will test the hypothesis that stimulus encoding will be modulated when attention is directed in the receptive field of the neurons. Such modulations have been shown to originate in the PFC, which targets layer 6 of sensory cortices. We will record all cortical layers simultaneously to test the hypotheses that modulation occurs in layer 6 first and is then transmitted to other layers. Finally, we will test the novel theory that NE may modulate attention by acting directly in sensory cortex. To this aim, we will conduct simultaneous barrel cortex and locus coeruleus recordings and examine the relationship of their stimulus-evoked responses (micro- and mesoscopic signals) during attention. We have been developing a novel animal model of attention that is amicable to genetics and physiology methods which are m
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'From Mother to Infant: Unveiling the Metabolic Transfer of Plant Bioactives During Pregnancy and Lactation' to be submitted under Horizon Europe.

assistant: **Abstract**

METABOFLOW aims to unravel the metabolic transfer of plant-derived bioactive compounds from mother to infant during pregnancy and lactation. Fruits and vegetables, the main dietary sources of phenolics, carotenoids, and alkaloids, provide compounds with antioxidant, anti-inflammatory, neuroprotective, and antimicrobial properties. These bioactives are increasingly recognized for their potential role in fetal growth, neurodevelopment, immune competence, and long-term health. However, more than 85% of pregnant and lactating women fail to reach the WHO-recommended intake of 400 g/day of fruits and vegetables, limiting neonatal exposure to these compounds and exacerbating health inequalities. Despite their relevance, there is a striking lack of quantitative evidence on maternal–fetal transfer during gestation and on maternal–neonatal transfer through breastfeeding, particularly beyond phenolic compounds.This fellowship will address these critical gaps by combining advanced mass spectrometry, nutrition, microbiomics, and statistical modelling to trace and quantify the flow of plant bioactives in the mother–infant dyad. Biological samples from two established European cohorts (MAMI and MILCH) will be analysed, including placenta, amniotic fluid, breast milk, meconium, urine, and faeces, allowing the identification of metabolites absorbed from the maternal diet and transferred to the infant. The project will characterise inter-individual variability linked to maternal diet, gut microbiota, and genetics, and define metabotypes associated with different neonatal exposures.By integrating multi-omics data, METABOFLOW will generate the first comprehensive map of bioactive compound transfer and its relation to early gut microbiota development. Outcomes will provide evidence-based kn
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Minimal solutions to nonlinear systems of PDEs' (MinSol-PDEs) under Horizon 2020.

assistant: **Objectives**

The aim of this proposal is to provide a systematic study of minimal solutions for a large class of nonlinear systems of PDE. Namely we will construct minimal solutions with predefined characteristics and investigate their qualitative properties, addressing the fundamental challenges that appear in the case of systems and which cannot be tackled with tools from the scalar case.The first part focuses on phase transition problems described by the Allen-Cahn system. This is a hot and difficult topic linking PDE with the theory of minimal surfaces. The main idea is to reduce the Allen-Cahn system to a Hamiltonian system in order to construct new classes of minimal solutions, and understand the conditions implying the reduction of variables (vector analog of the celebrated De Giorgi conjecture).   In the second part, our focus is on the Painlevé equation which plays a crucial role in areas as diverse as random matrices, integrable systems, and superconductivity. The objective is to classify and investigate the minimal solutions of  Painlevé-type systems in low dimensions. These have direct applications in the study of vortices in liquid crystals and Bose-Einstein condensates. The proposed approach connects the Painlevé equation with a singular problem, easier to study. The fellow has a strong research record on the Allen-Cahn system (a book + 6 papers), and has also worked on the Ginzburg-Landau model of liquid crystals. On the one hand, he will develop his own innovative approaches to the proposed problems, and transfer his expertise to the host. On the other hand, at BCAM and through a secondment, he will link his previous research on liquid crystals to other alternative models (for which the supervisor is a world-leading expert), and to the theory of Bose-Einstein condens
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'A global approach for recovery of arable land through improved phytoremediation coupled with advanced liquid biofuel production and climate friendly copper smelting process' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Phy2Climate will validate 5 phytoremediation pilots in Spain (South Europe), Serbia (Balkan region), Lithuania (Baltic region), Argentina (South America) and India (South Asia) at TRL-5. The selected contaminated sites represent the most common soil contaminants worldwide. The phytoremediation pilots will produce energy crops with none indirect Land Use Change (iLUC) issues. The energy crops will feed a pilot biorefinery in Germany that combines cutting edge biomass processing technologies to produce 4 types of clean drop-in biofuels for the road and shipping transport sectors at TRL-5: EN 14214 biodiesel, ISO 8217 marine fuels, EN 590 diesel and EN 228 gasoline. Additionally, bio-coke will be also produced as substitution of petroleum coke in the metallurgical industry. A significant cost reduction in factor >5 for phytoremediation compared with common remediation techniques is target together with conversion costs of drop-in biofuel production <0,45 €/l. The global biofuel production potential of the Phy2Climate approach is estimated up to 137 million m3 per year. Furthermore, estimated specific Greenhouse Gas (GHG) mitigation of the produced drop-in biofuels is 149% compared with the fossil equivalents, resulting in a total saving potential of 500 Mega-tones CO2eq per year. The work programme is divided in 7 work packages that are specifically designed to achieve the objectives of the project as well as to contribute to the Mission Innovation Challenge 4 and to 16 UN Sustainable Development Goals. The Phy2Climate consortium unites 17 partners from 10 different countries with strong interdisciplinary expertise in the fields of project management, soil remediation & phytoremediation, advanced biofuel technologies, environmental and social sustainability, legal analysis
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'The Kaehler-Ricci flow and Singular Calabi-Yau manifolds' (KRF-CY) targeting Horizon 2020.

assistant: **Abstract**

Smoothing properties of the Kaehler-Ricci flow have been known and used for a long time. Attempt to run the Kaehler-Ricci flow from a degenerate initial data has been of great interest in the last decades. The bet result so far was recently obtained by Guedj and Zeriahi that were able to define the maximal flow for any initial current with zero Lelong number. This initial current will be smoothed out immediately. One example was also given showing that there might be no regularity at all in the case of Fano manifolds when starting from a current with positive Lelong number. However it is expected that the regularizing effect happens outside analytic sets. The first goal of this proposal is to prove such a regularity result.  In the last few years, Eyssidieux, Guedj and Zeriahi have shown that every Calabi-Yau variety admits a unique singular Kaehler-Ricci flat metric. Their work establishes the existence of such singular Kaehler-Ricci flat metric but it does not establish the expected asymptotic behavior near the singular points. The main goal of my proposal is to study the asymptotic behavior and the regularity properties of these metrics/potentials near singularities. More generally, given a Kaehler-Einstein metric on a singular variety, it would be interesting to understand how we can relate the asymptotic behavior of  such a metric near to the singularities of the variety.  Such a result would be of great interest also in theoretical physics. Indeed, since the seminal paper of Candelas and de la Ossa in the 90's, physicists have guessed that Calabi-Yau 3-folds with the simplest isolated singularities should admit incomplete Kaehler-Ricci flat metrics which near each singularitiy look like the conifold metric. A related goal would be to go after the  analogies by the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Advancing Circular Economy Adoption in EU's PAs: A Realist Evaluation and Evidence-Informed Approach' (CircTourEU) under Horizon Europe.

assistant: **Objectives**

The CircTourEU project addresses pressing environmental challenges in the protected areas (PAs) in EU by applying Circular Economy(CE) principles to tourism. CE promotes resource reuse and sustainability, vital for combatting overtourism, greenhouse gas emissions,and biodiversity decline. Rural regions heavily dependent on tourism face these challenges and require innovative resourcemanagement and governance. The Southern Mediterranean hosts many European PAs, facing tourism surges. To protect thesehabitats, a systematic shift to CE involving small and medium enterprises (SMEs) is crucial. Yet, SMEs in EU tourism lack research andinnovation focus, necessitating rural research and innovation pilots.Led by Dr Ante Mandić, supervised by Prof Xavier Font and Dr James Kennell, the CircTourEU project evaluates CE transition projectsfor tourism SMEs in the EU. It tests innovative methods in pilot PAs in Spain, Italy, Croatia, and Greece to promote evidence-based CEpractices in the tourism industry. CircTourEU's innovation lies in using complexity science-based realist evaluation to understandbarriers to innovation and knowledge integration in PAs. This approach offers nuanced insights into intervention effectiveness. Theproject recognises the importance of macro-level sustainability transitions and empowering rural SMEs with innovative CE businessmodels. It considers context-dependent barriers and tailors strategies to unique PA governance and management contexts.CircTourEU aims to empower PA authorities for evidence-based CE transitions and disseminate knowledge for widespreadimplementation. Following the EU's ""evaluation first"" principle contributes to evidence-based decision-making, aligning with theEuropean Green Deal and Circular Economy Action Plan. The project provide
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Electronic active power meter for networks with non-rigid frequencies' will create measurable scientific, societal and economic impact aligned with Fourth Framework.

assistant: **Impact**

The objective of the RTD-project is in the research of the thechnological basis of wattmeter measuring systems for variable frequences in the range of 2 to 2.000 Hz in feed back to frequency regulated speed control of electric motion. This wattmeter-system referred to the output of the frequency regulator causes a tremendous effect in saving electric energy. The principal of operation is a non-selective frequency circuit by using optocouplers.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Processes Influencing Democratic Ownership and Participation' in the context of a Seventh Framework call.

assistant: **Objectives**

This project will examine the processes which influence democratic ownership and participation in eight European states. It will draw on the disciplines of Politics, Sociology, Social Policy, Psychology and Education to examine macro-level contextual factors (including historical, political, electoral, economic and policy factors), proximal social factors (including familial, educational and media factors) and psychological factors (including motivational, cognitive, attitudinal and identity factors) which facilitate and/or inhibit civic and political engagement and participation. The research will be ground-breaking in incorporating the psychology of the individual citizen within its scope, and it will be distinctive in addressing the psychological processes through which political, societal and social factors have their effects upon citizens’ civic and political engagement and participation. Young people, women, minorities and migrants will be examined as four specific groups at risk of political disengagement. The research will focus on the differences, as well as the overlap, between civic and political engagement, and on both direct and representative participation. An innovative multi-level process model of civic and political engagement and participation will be constructed, which will explain how and why different forms and interpretations of democratic ownership and participation develop or are hampered amongst citizens living in different European countries and contexts, with particular attention being paid to the relevant phenomena at regional, national and EU levels. Appropriate stakeholders at regional, national and EU levels will be involved in all stages of the work, to ensure that the research addresses issues of direct concern to these stakeholders, and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'One device to measure the most important air pollutants and greenhouse gases at once'.

assistant: **Objectives**

EU air monitoring authorities, industries and research centers struggle to acquire pollution data to develop concrete emission reduction strategies. To monitor each individual polluting gas, it is necessary to perform analyses in separate, bulky and expensive instruments, placed in fixed monitoring stations. These instruments face financial, logistical and data limitations, because they are expensive, not portable and require regular calibration and continuous operation by expert technical staff. At MIRO Analytical Technologies we have developed EnviroLAS, the first all-in-one instrument for advanced pollution monitoring, allowing the measurement of 6 different pollutants (CO, O3, SO2, NO, NO2, NH3) and 4 greenhouse gases (H2O, CO2, CH4 and N2O) continuously, simultaneously and precisely through a light and easily transportable device based on direct laser absorption spectroscopy. Our feasibility plan was developed under a Ph1 grant and now we seek an Accelerator grant to launch EnviroLAS into the market. During the project we plan to add key components to EnviroLAS hardware and upgrade our software and user interface. We will refine the present manufacturing process and define the industrial scale-up process, after performing external testing of EnviroLAS with early adopters. We will certify EnviroLAS in EU and US, and consolidate our exploitation plan, targeting all Europe by 2024 and expanding to US by 2026. EnviroLAS will have 75% less operational costs, 40% lower startup costs, and reduced dimensions (60x50x15cm) and weight (25kg) compared to existing devices. It will address the urgent demand to monitor main air pollutants and greenhouse gases in-situ in a more cost-effective and dynamic way. The EC contribution is fundamental to scale-up our business and create 2