RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Model-Based Construction And Optimisation Of Versatile Chassis Yeast Strains For Production Of Valuable Lipid And Aromatic Compounds'.

assistant: **Objectives**

CHASSY will unlock the full potential of the yeasts Saccharomyces cerevisiae, Yarrowia lipolytica and Kluyveromyces marxianus as cell factories for production of high value compounds which have applications in the cosmetic, nutraceutical and white biotechnology sectors. Current cell factory strains for these classes of product are restricted to proof-of-principle levels because of limited precursor supply, poor product tolerance and lack of versatility. CHASSY addresses these challenges by redesigning metabolic circuits and expanding the host range to include the oleaginous yeast, Y. lipolytica and the thermotolerant yeast, K. marxianus. The systems biology approach will integrate model-based design, construction and analysis of yeast strains, resulting in reconfigured metabolic networks optimised for the production of lipid and aromatic molecules. Construction of the chassis strains, using new and existing synthetic biology tools, will be directed by knowledge derived from a thorough systems biology comparison of the three yeast species, conducted using integrative data analysis and genome scale metabolic models. The chassis strains will be used to build cell factories to produce three specific high value products: the oleochemicals, Docosanol and Octanoic acid; and the aromatic molecule, Amorfrutin 1. These new cell factory strains will be evaluated under industrial conditions to produce data that will further improve the chassis platforms. The major outcomes of this project will be (1) a new set of chassis yeast strains that are widely applicable for development of industrial cell factories; (2) the knowledge and technology to readily build and evaluate new chassis tailored to specific applications; (3) prototype cell factory strains producing three high value metabo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Evaluation of FRACMAT test for specifications' (1994-1998), addressing dissemination and exploitation.

assistant: **Impact**

The Objectives To improve upon their competitive position in the world market, it is essential that European spring manufacturers make products that are dimensionally consistent and accurate. One of the major sources of variability in spring manufacture arises from the wire used as the raw material, but none of the national or international specifications for spring wire contain an effective test method for evaluation of wire variability. Joint work by SRAMA and the University of Warwick Mathematics Institute has produced the FRACMAT test machine, which quantifies the sequential elastic/frictional wire variability by computerised Statistical and Chaos Theoretic analysis techniques. This project is designed to confirm that the FRACMAT test is a fast, inexpensive, robust and reliable method for evaluating wire variability over a wide range of spring wire sizes and qualities, and to generate a high level of confidence in the test among leading European spring wire producers and SME spring manufacturers. Benefits Incorporating the FRACMAT test into wire specifications will provide the following important benefits: For wire producers * An increased level of confidence that wires of high consistent quality can be reliably supplied to customers. * Identification of wire process routes for the most consistent product. thereby producing wires 'right first time' at lowest cost. * Ability to distinguish between wire induced coiling problems and those created by user. For Springmakers * Shorter set-up times and reduced scrap by elimination of inconsistent wire. * A genuine Just-In-Time production capability reducing inventory levels and enhancing customer service. * Improved ability to specify consistent wire for critical orders. The Projcet The intended research will generate/anal
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Conserved Environmental Programs of Streptophyte Cells' in the context of a Horizon Europe call.

assistant: **Objectives**

A single monophylum accounts for our entire macroflora: the embryophytes, thus referred to as land plants. Emerging from streptophyte algae, the embryophyte lineage successfully established itself and massively radiated on land. What allowed for this singular success story? One of the features strictly required and particularly prominent in land plants is the ability to adjust their growth and physiology according to environmental cues specifically encountered in terrestrial habitats. Land plant physiology is plastic. This plasticity hinges on a flow of information from sensing cues to adjusting internal programs. Here, my team and I will study the evolution of this flow of information to establish what defines this program. In the last decade, research into early plant evolution has moved from a clarification of who the closest relatives of land plants are to an understanding of which genes are shared across 600 million years of streptophyte evolution. Key genes for stress response previously thought specific to land plants are in fact active in their algal relatives. Now, with first genetic tools for these algae at hand we can establish how evolution has assembled these ancient genes into functional molecular programs that underpin decisive traits inherent to streptophyte cells. These traits concertedly act in a single cell. Sub-functionalization of these genes has yielded a flow of form and function in land plants, obscuring their core functions. We will combine genetics and high-throughput assessment of a unicellular alga and cell suspension cultures in land plants to study the core gene network hierarchy for acclimation to environmental perturbation. Using network analyses for data integration that build on genetic manipulation, time-course phopshpoproteomics and t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'OPerational Trustworthiness Enabling Technologies' in the context of a Seventh Framework call.

assistant: **Objectives**

The OPTET project plans through a multi-disciplinary and integrated approach to identify and address the drivers of trust and confidence also fight against its erosion (especially true on the Internet or Cloud). Focus of this project is on socio-technical systems connected to the Internet. The resulting technologies enabling trustworthiness would be verified on two distinct existing execution platforms to demonstrate genericity of OPTET outcomes.  Potential of OPTET results will be demonstrated and evaluated in the context of two operational use cases one in the domain of Ambient Assisted Living (AAL) and second Cyber Crisis Management. Overall, the OPTET project will significantly increase  the trustworthiness of IT and Services and thus strengthen the competitiveness of the European software and service industry. In doing so OPTET will provide a powerful foundation for designing and developing trustworthy system/services/apps stakeholders can trust (since provable also guaranteed) for the future internet realizing its promises.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Mechanisms of stem cell population dynamics and reprogramming' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

How complex but stereotyped tissues are formed, maintained and regenerated through local growth, differentiation and remodeling is a fundamental open question in biology. Understanding how single cell behaviors are coordinated on the population level and how population-level dynamics is coupled to tissue architecture is required to resolve this question as well as to develop stem cell (SC) therapies and effective treatments against cancers.As a self-renewing organ maintained by multiple distinct SC populations, the epidermis represents an outstanding, clinically highly relevant research paradigm to address this question. A key epidermal SC population are the hair follicle stem cells (HFSCs) that fuel hair follicle regeneration, repair epidermal injuries and, when deregulated, initiate carcinogenesis. The major obstacle in mechanistic understanding of HFSC regulation has been the lack of an in vitro culture system enabling their precise monitoring and manipulation. We have overcome this barrier by developing a method for long-term maintenance of multipotent HFSCs that recapitulates the complexity of HFSC fate decisions and dynamic crosstalk between HFSCs and their progeny.This breakthrough invention puts me in the unique position to investigate how HFSCs self-organize into a network of SCs and progenitors through population-level signaling crosstalk and phenotypic plasticity. This project will uncover the spatiotemporal dynamics of HFSCs fate decisions and establish the role of the niche in this process (Aim1), decipher key gene-regulatory networks and epigenetic barriers that control phenotypic plasticity (Aim2), and discover druggable signaling networks that drive bi-directional reprogramming of HFSCs and their progeny (Aim3). By deconstructing complex tissue-level beh
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'Broadband optical network using atm pon access facilities in realistic telecommunications environments'.

assistant: **Concept**

The main objectives of the project are to demonstrate:that a broadband ATM PON is flexible, reliable and cost-effectivethat applications and services using ATM make efficient use of available resources and bandwidththat such applications and services fulfil real user needsthat system management issues for shared access can be resolvedinteroperability between ATM IBC islands through the Pan European ATM Network.Results are expected on two levels:network level: assessment of the performance of a broadband ATM PON under real life conditions, with real users and real traffic, reliability of the system, robustness and fault toleranceservice/application level: assessment of performance and suitability of ATM for broadband applications and services for small businesses by analysis of user feedback and evaluation of sites.Expected ImpactTo stimulate the deployment of ATM in the access area for both small business and residential usersTo trigger the commercial exploitation of multimedia broadband applications in the sectors of tele-medicine and tele-teaching.Main contributions to the programme objectives:Main deliverablesEnhancement of the ATM PON BAF prototype system.Contribution to the programmeSignificant contributions to ETSI on the standardisation of the VB5 interface and support for the world wide FSAN (Full Service Access Network) initiative, which resulted in the rapid approval of the ITU-T G.983 recommendation on ATM-PON systems.Technical ApproachFour user trials, in four different countries, will be defined and the users provided with applications, in the area of tele-medicine and tele-teaching, according to real user needs. In two trial sites an enhanced release of the broadband access system developed by the RACE II project R2024 BAF will be deployed. The trial sites
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Generation of mumps virus vaccine vectors for heterologous antigens.' (1998-2002), addressing dissemination and exploitation.

assistant: **Impact**

Generation from cDNA of recombinant Mumps viruses capable of expressing one or more metrologies antigens; molecular, biochemical and immunologist characterisation of rescued viruses; determination of the vaccine potential of the recombinant Mumps virus vectors.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'OPEN and co-created ViRtual worldS for Europe' under Horizon Europe.

assistant: **Concept**

Europe calls for the emergence of virtual worlds that characterises themselves for being open, transparent, inclusive, ethically and environmentally responsible, but also capable of restoring the technological sovereignty of EU industry in the global scenario of competition. Such European virtual worlds would foster the following benefits: a) Higher accessibility, greater freedom and control, lower barriers to entry and more equitable distribution of resources; b) Interoperability, privacy and security as well as data ownership: open human-centric virtual worlds would be able tointeroperate with each other; c) More innovation, creativity, and social benefits: open human-centric virtual worlds would foster a collaborative environment where developers and users could work together to create new experiences and features. In that regards, the overarching aim of OPENVERSE is to contribute to laying the foundations of such European virtual worlds by establishing a knowledge base on it, setting up and animating a community of stakeholders, testing a methodology that combines user co-creation and XR in real world cases of industrial and societal relevance, exploring relevant ethical, legal, IPR and single market challenges, and producing industry standards as well as a technology andpolicy roadmap and recommendations to guide the future establishment of the Open virtual worlds concept in Europe and worldwide.


**Keywords:** Human-centric metaverse, open metaverse, co-created metaverse, technology foresight, research and policy roadmap, standardization, technology watch, market place, ethics, IPR and governance model
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Tipping Points in Ecological Networks' (TipPEN) targeting Seventh Framework.

assistant: **Abstract**

Ecosystems occasionally respond abruptly to small changes in external conditions. Such abrupt responses can represent critical transitions that occur at tipping points where the ecosystem shifts to an alternative regime. Despite the often profound consequences of tipping events, our ability to predict them is still limited. To meet this challenge, generic early-warning signals for critical transitions have recently been proposed. These signals are generic, because they may in principle work irrespectively of the specific mechanism responsible for the tipping, making their potential field of application very broad. However, they have so-far been mostly analyzed in simple models that neglect the high spatial and structural complexity that characterizes most ecosystems. The proposed project aims to help bridging this gap between complex reality and simple models by 1) analyzing how critical transitions arise in spatially and structurally complex ecological networks, and 2) investigating how this kind of critical transitions might be detected by generic early-warning signals. The anticipated results will be of more than academic interest, as the complex webs of interactions in nature are under increasing pressure and there is an urgent need to understand how we may estimate the risk of systemic collapses.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Deterministic Generation of Polarization Entangled single Photons Cluster States' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Measurement based quantum computing is one of the most fault-tolerant architectures proposed for quantum information processing. It opens the possibility of performing quantum computing tasks using linear optical systems. An efficient route for measurement based quantum computing utilizes highly entangled states of photons, called cluster states. Propagation and processing quantum information is made possible this way using only single qubit measurements. It is highly resilient to qubit losses. In addition, single qubit measurements of polarization qubits is easily performed with high fidelity using standard optical tools. These features make photonic clusters excellent platforms for quantum information processing.Constructing photonic cluster states, however, is a formidable challenge, attracting vast amounts of research efforts. While in principle it is possible to build up cluster states using interferometry, such a method is of a probabilistic nature and entails a large overhead of resources. The use of entangled photon pairs reduces this overhead by a small factor only.We outline a novel route for constructing a deterministic source of photonic cluster states using a device based on semiconductor quantum dot. Our proposal follows a suggestion by Lindner and Rudolph. We use repeated optical excitations of a long lived coherent spin confined in a single semiconductor quantum dot and demonstrate for the first time practical realization of their proposal. Our preliminary demonstration presents a breakthrough in quantum technology since deterministic source of photonic cluster, reduces the resources needed quantum information processing. It may have revolutionary prospects for technological applications as well as to our fundamental understanding of quantum systems.We p
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Lubricated scaffolds for tissue engineering' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

Osteoarthritis (OA) is a painful joint disorder affecting millions of sufferers worldwide, and occurs through formation oflesions followed by degradation of the articular cartilage layer coating the major joints. Repair of such lesions via tissueengineering has been one of the most promising directions for alleviating OA. The rationale behind this is that the cartilage lesions regenerate after implantation of a scaffolding matrix incorporating desired cell types. Limited clinical success partially originated from the lack of suitable interfacial properties of the scaffolds. We have applied recently revealed concepts on hydration interactions (on some of which we hold a patent), which, we believe, will lead to a significant advance inscaffold-based treatment of cartilage lesions. This applies in particular to the development of scaffolds with modified interfacial properties, which are essential for repairs of large lesions. This is realized by fabricating suitable scaffolds with suitable additives, whose properties form an integral part of our associated ERC project. This Proof of Concept project,which thus ties in closely with our ERC project, consists of several workpackages. An integral part of the plan of work will establish proof of the feasibility of the idea through modification, characterization and mechanical fine-tuning of scaffolds for cartilage compatibility. The other workpackages, which are at the heart of this project, will examine the prospects of commercializing such scaffolds for clinical applications, via multifaceted market studies; identification of possible partners;and development of an appropriate business model.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Research project for cockle fishing gear improvement and environmental impact reduction.' (1998-2002).

assistant: **Innovation**

Mechanical cockle fishery makes use of a suction dredging system that has been modified continuously in order to minimize damage to the product and by-catch. Further improvement to reduce sediment disturbance are promising but require a scientifically based technological approach. Improvement of the fishing gear and techniques is focused on the reduction of damage to the benthicenvironment, including sediment, benthos and juvenile cockles and aims for a better product quality (reduction of sand content and damage to the cockleshells). At present the main problem with technical improvement is the adjustment of the water jet in front of the gear and the transport of cockles on-board. The idea is to develop a more gentle flow and still achieve resuspension of cockles meanwhile minimizing resuspension of sediment and biota, to develop a more gentle transport system to minimise sand content and damage to the cockle shells and to evaluate the yield as a function of effort.