RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Biopharmaceuticals purification by continuous membrane-assisted crystallization achieving lower cost and intensified processes' (BIOPURE).

assistant: **Innovation**

With the growing global demand for biological medicines to address new therapeutic areas, the BIOPURE project will deliver a step change in monoclonal antibodies (mAbs) purification through the implementation of radically new and disruptive technology to recover mAbs-products in the solid-state directly from cell-free culture fluids. BIOPURE promises to lower manufacturing and purchase of equipment costs with a smaller footprint. It simplifies logistic chains and enhances environmental sustainability by avoiding extensive use of chemicals, compared to the standard chromatography-based platforms. It opens the doors to new possibilities and biomedicines so far too challenging economically or technologically. As end result, the citizens will have access to a more affordable and diverse selection of new generation biomedicines. The proposed membrane-based technology has already been proved at the laboratory scale (TRL4) as a cheaper and easily scalable alternative to protein A chromatography for mAb purification. The next step is to demonstrate the generalized efficiency of the technology and scale it up to TRL6 through the design of a fully automatized prototype that will be operated continuously and capable of compliance with quality and regulations for biopharmaceutical productions. In addition to technological development, the new BIOPURE technology will be validated with real market players, leading to verifying the planned business model, the IPR management plan, and the associated financial planning included in the go-to-market strategy. By achieving the main objectives of BIOPURE, it is expected that the adoption of membrane-assisted method for mAb-products purification will provide a breakthrough advancement in terms of productivity efficiency via continuous manufa
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Unleashing the potential of narrow leaf lupin as locally grown protein crop' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Europe is in great need of a locally produced protein crop as it imports 70% of its protein requirements. Narrow-leafed lupin (Lupinus angustifolius, NLL) represents an excellent candidate. It is native to Europe, able to fix atmospheric nitrogen and produces high-protein grain (up to 40%). However, toxic alkaloids in the grain (quinolizidine alkaloids, QAs) prevent its widespread cultivation. Cultivars with low QA levels in all tissues are available; however, these are susceptible to herbivores, and grain QA content often surpasses safety thresholds. Interestingly, QAs are not produced in the grain, but are transported to the grain from vegetative tissues. Thus, I propose to specifically eliminate QAs from grain using a transport engineering approach without compromising defenses in vegetative tissues. In this UnleashLupin project I will discover and characterise the unknown transport proteins involved in translocating QAs to the grain. For this, I will combine my background in NLL genetics and genomics with the expertise of the Nour‒Eldin laboratory, which is world-leading in the field of plant specialised metabolite transport. Candidate genes will be selected from recently generated resources, and they will be tested for transport activity (e.g. in Xenopus oocytes) and cellular/sub-cellular localization. Techniques for in planta characterization (e.g. virus-induced gene silencing) will be provided by the Geu-Flores laboratory, which is currently investigating QA biosynthesis in NLL. The outcome will significantly advance the emerging field of long-distance transport of plant specialised metabolites. It will also be instrumental in the development of a locally grown high-value, herbivore-resistant NLL crop that accumulates little or no QAs in the grain but retains QAs
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'First responder Advanced technologies for Safe and efficienT Emergency Response'.

assistant: **Concept**

The term first responders usually refers to law enforcement, fire, and emergency medical personnel. These responders, however, are not the only assets that may be required in the aftermath of a strike on the homeland. In contrast, the more appropriate term, emergency responders, comprises all personnel within a community that might be needed in the event of a natural or technological (man-made) disaster or terrorist incident. These responders might include hazardous materials response teams, urban search and rescue assets, community emergency response teams, anti-terrorism units, special weapons and tactics teams, bomb squads, emergency management officials, municipal agencies, and private organizations responsible for transportation, communications, medical services, public health, disaster assistance, public works, and construction. In addition, professional responders and volunteers, private nonprofit, nongovernmental groups (NGOs), such as the Red Cross, can also play an important role in emergency response. As a result, the tasks that a national emergency response system would be required to perform are more complex than simply aiding victims at the scene of a disaster, carried out by several kinds of professional users with different roles and expertise. Moreover, emergency preparedness and response lifecycle is a complex process that consists of the preparation, response, and recovery from a disaster, including planning, logistical support, maintenance and diagnostics, training, and management as well as supporting the actual activities at a disaster site and post-recovery after the incident.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Ion-Molecule Processes for Analytical Chemical Technologies' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Soft chemical-ionization mass-spectrometry (SCIMS) is an exquisitely sensitive analytical technique with applications to health, the environment and security that are vital to the EU. However, the recent, rapid and widespread adoption of this technique has caught Europe unprepared. The resultant shortage in analytical chemical expertise has created an urgent need for highly skilled young researchers to be trained in the wide variety of SCIMS methods. IMPACT addresses this skills’ shortage by establishing an intersectoral and multidisciplinary SCIMS training network. IMPACT also brings cohesion to the fragmented SCIMS research and development activities within the EU. To date, most SCIMS developments have been driven not by users but by manufacturers, whose main focus has been on increased sensitivity. However, just as crucial is improved selectivity. Indeed, many users consider improved selectivity to be the key to taking SCIMS technology to a whole new level. Instead of private and public sectors working independently, we need a fresh, intersectoral approach. IMPACT will achieve this through intersectoral work packages and multidisciplinary research projects. In place of major and costly changes in instrumental design, IMPACT’s projects will focus on developing new methods for improved chemical specificity by manipulating ion chemistry. Hence, IMPACT’s fresh approach will produce a step change in SCIMS instrumentation to deliver both economic and societal benefit to the EU. Specifically, IMPACT will train 10 ESRs within an integrated partnership of commercial, governmental and academic organisations, with planned secondments, 5 Advanced Training Courses, 7 interactive Complementary Skills Workshops, and 4 ESR Centred Research Meetings. IMPACT will therefore provide Eur
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Determination of the three-dimensional structure in solution of the complex between single-stranded dna binding protein of phage 029 and dna' (1994-1998) under Fourth Framework.

assistant: **Objectives**

CONTENT OF THE PROJECT 029 SSB binds to single-stranded DNA (ssDNA) stimulating viral DNA replication. This project is aimend to yield a three-dimensional structure of the ssDNA-029 SSB complex by NMR. OBJECTIVES I-Determination of the three-dimensional structure in solution of 029 SSB.  The size of 029 SSB in solution makes it a suitable system to be analyz by NMR. We propose to determine the three-dimensional structure of the complex by isotopic labeling with either 15N or 13C (Folkers et al., 1994). II-Identificatiora of amino acids involved in binding to ssDNA.  Spin-labeled oligonucleotides (Folkers et al., 1993) and lanthanide-chelate complexes (van Duynhoven et al., 1993) should allow to obtain information about those protein regions and residues involved in binding to single-stranded DNA. III-Determirnation of the three-dimensional structure in solution of the ssDNA-029 SSB complex.  To determine the three-dimensional structure of the ssDNA-029 SSB complex, the protein will be labeled with 15N or 13C, leaving unlabeled the ligand (i.e., at natural isotopic abundance).
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Microbiota modulation through horizontal gene transfer.'.

assistant: **Innovation**

My goal is to determine horizontal gene transfer (HGT) rates of specific functions within the gut microbiome. The microbes on and within our bodies, especially within our gastro-intestinal tract, are intimately connected with our immune system and promote health in myriad ways. Altering our gut microbiota (GM) composition and/or function might thus improve health. My research in the Jeroen Raes lab led to the realization that changing species abundances through dietary or lifestyle modulation may be difficult because of the small effect sizes of the factors influencing GM composition (e.g. diet, medication, or transit time). In addition, host-selection and competition of resident microbes, might limit the strain engraftment necessary for the effect of fecal transfers and probiotic cocktails. Despite initial successes (e.g. C. difficile infection treatment), current modulation strategies might therefore be less successful with other conditions. I contacted Ilana Brito, in order to find out whether HGT - a process in which prokaryotes exchange genetic material - may serve as an alternative way to modulate the residing GM. Little is known about the features that affect HGT rates within natural environments nor the role of selection in that process. If these were well-understood, it would allow to assess the possibilities of extending the gut microbiome with additional functions. During my research stay, I will experimentally determine HGT rates within the animal gut under natural and HGT-enhancing conditions. In addition, I will develop methods to examine HGT in metagenomic datasets and determine the relative importance of the factors influencing HGT (selective pressure, host health and DNA delivery method). The knowledge generated through this MSCA-fellowship will stimula
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Environmental biotechnology research centre' demonstrating excellence, impact and implementation quality for a Fifth Framework call.

assistant: **Abstract**

The main goal of Demeter project is the creation of Environmental Biotechnology Centre with R&D potential adjusted to the high European level and to the economic and social needs of the region of Upper Silesia and being a leading centre in environmental biotechnology in Poland. The Centre will increase its R&D potential by acquiring co-treatment techniques and ecotoxicological risk assessment knowledge within twinning arrangements with 2 European centres, established contacts with other EU and Eastern European partners and Ph.D students exchange. The Centre proposes organising international conference on Soil and Groundwater Bioremediation" as a platform for knowledge and experience exchange among European specialists in environmental biotechnology. The post-graduated studies and workshop in ecotoxicology as well as the different courses on EU law will ensure the Centre position of the leading training centre in the region."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Uncovering Ion-Electron Interactions in Organic Mixed Conductors', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Organic mixed ionic-electronic conductors (OMIECs) have risen as a promising material choice for bioelectronic devices due to their low impedance, soft mechanical properties, and ability to transduce ionic signals to electronic currents. The ion-electron interactions, which are unique to mixed conductors, have been exploited to produce high performance sensors and electrophysiological recording devices. However, the fundamental interactions between ions and electrons that determine the performance of these materials is still poorly understood, impeding their translation from a research setting to commercial use. This proposal aims to address this gap in knowledge using state-of-the-art analysis of the nanoscale electronic and chemical properties to better understand the macroscale materials performance.The proposed project consists of three central goals: (1) direct observation of nanoscale ion-electron interactions in OMIECs, (2) identifying the relationship between these interactions to OMIEC materials properties, and (3) leverage the findings to optimise next-generation bioelectronic devices. Spectroscopic scanning transmission electron microscopy (STEM) techniques will be used to study the spatial distribution and electronic structure of ions in OMIEC films during operation with ultra-high spatial resolution. Optical spectroscopy and electronic characterisation will be used to study the transport properties of ionic and electronic charge carriers in OMIECs. The work will be supervised by Prof. Malliaras, an expert in both fundamental physics of OMIECs and their clinical applications, Prof. Ducati, an expert in advanced multidimensional STEM techniques, and Dr. Rao, an expert in optical characterisation of organic semiconductors. The fundamental insights drawn from i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Identification of legal rules and administrative processes applicable to Fuel Cell and Hydrogen technologies’ deployment, identification of legal barriers and advocacy towards their removal.' to be submitted under Horizon 2020.

assistant: **Abstract**

The fuel cells and hydrogen (FCH) industry has made considerable progress toward market deployment. However existing legal framework and administrative processes (LAPs) – covering areas such as planning, safety, installation and operation – only reflect use of incumbent technologies. The limited awareness of FCH technologies in LAPs, the lack of informed national and local administrations and the uncertainty on the legislation applicable to FCH technologies elicit delays and extra-costs, when they do not deter investors or clients.This project aims at tackling this major barrier to deployment as follows:   • Systematically identifying and describing the LAPs applicable to FCH technologies in 18 national legal systems as well as in the EU proper legal system.   • Assessing and quantifying LAP impacts in time and/or resource terms and identify those LAP constituting a legal barrier to deployment.    • Comparing the 18 countries to identify best and bad practices   • Raising awareness in the countries where a LAP creates a barrier to deployment.    • Advocating targeted improvements in each of 18 countries + EU level   • It will make all this work widely available through: (1) A unique online database allowing easy identification, description and assessment of LAPs by country and FCH application. (2) Policy papers by applications and by country with identification of best practice and recommendations for adapting LAP. (3) A series of national (18) and European (1) workshops with public authorities and investors.HyLAW sets up a National Association Alliance not just for the duration of the project, but for the long term consolidation of the sector under a single unified umbrella. By bringing together these national associations and all of Hydrogen Europe’s members, it’s the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'COGNITIVE PLANTS THROUGH PROACTIVE SELF-LEARNING HYBRID DIGITAL TWINS'.

assistant: **Objectives**

While the concept of digitalisation and Industry 4.0 is making rapid inroads into the European manufacturing sector, there are several aspects that can be still incorporated into the system which can strengthen the goal of optimal process operations. One such aspect to the digitalisation vision is the ""cognitive element"", where the process plants can learn from historical data and adapt to changes in the process while also being able to predict unwanted events in the operation before they happen. Through this project, COGNITWIN (Cognitive digital Twin), we aim to add the cognitive element to the existing process control systems and thus enabling their capability to self-organise and offer solutions to unpredicted behaviours.  To achieve the objectives of the project, we have partnered with six industries and seven research groups from seven European nations, each of whom will bring their expertise in data analytics and pattern recognition which are going to be at the heart of the COGNITWIN solution platform. The set-up of the platform includes a sensor network that will continuously monitor and collect data from various plant processes and assets which will be stored at a database. This data will be used to develop a digital twin of the process and will also be used to develop models with cognitive capability for self-learning and predictive maintenance which will lead towards optimal plant operations.  The project builds on ideas and technologies that have been validated in controlled environments (TRL 5) to arrive at prototype demonstrations in operational environments (TRL 7). The COGNITWIN project results will be implemented to our industrial partner's processes to demonstrate the transition from TRL 5 to TRL 7. TRL – Technology Readiness Level""


**Keywords:** C
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'AUDITORY-MOTOR PATTERNING OF MUSIC PERFORMANCE VIA MULTI-MODAL ANALYSIS OF PLAYING TECHNIQUE' (MUSMAP), addressing dissemination and exploitation.

assistant: **Impact**

MUSMAP develops research on the topic of auditory-motor interaction, using music performance as a case study. The project will address methodological and technological challenges in the development of multi-modal data acquisition and analysis methods for the construction of auditory-motor patterning schemes, with the aim of modelling instrumental playing technique from a computational perspective. Violin performance, which involves time-continuous feedback adaptations through tightly-coupled action-perception interaction, represents a rich and underexplored case study.The research to be pursued in MUSMAP is divided into three main parts:(1)To utilize multi-modal data acquisition and analysis methods to develop and validate auditory-motor pattern representation models by creating and systematically studying an extensive set of violin performance multi-modal recordings of trained musicians.(2)To apply auditory-motor pattern representations to design a system for automatic control of violin sound synthesis presenting a closed-loop, feed-forward architecture by which a motor sequencing component is updated in response to perceptual features of synthesized sound. Beyond its interest as a promising technology for upcoming computer-aided music production frameworks, the system represents an ideal test bed for validating the auditory-motor representation models developed as part of objective (1).(3)To apply auditory-motor pattern representations to develop novel, high-quality sound processing technologies through which meaningful audio perceptual attribute manipulations are driven by motor primitives, enabling auditory-motor remapping of recorded or real-time violin performances. In collaboration with top-class institutions specialized in cognitive neuroscience aspects of senso