RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Continuous monitoring systems for the SAFE storage, distribution and usage of Hydrogen POWER for transport' (2007-2013) under Seventh Framework.

assistant: **Objectives**

The limited supplies of traditional fossil fuels and environmental damage caused by their CO2 emissions have caused a growing interest in the exploitation of renewable energy sources. By far the most promising replacement fuel for road transport is hydrogen because of its abundance, efficiency, low footprint for carbon and the absence of other harmful emissions. In 2015 it is expected that the number of hydrogen fuel installations will exceed a hundred thousand units.Because hydrogen can react explosively with air there is inevitably public apprehension about using hydrogen as a mass market fuel that can inhibit wider commercialisation. Technical issues regarding hydrogen storage leakage are (i) the small size of the H molecule which causes it to diffuse through relatively open structured materials such as composites, and (ii) the phenomenon of Hydrogen Embrittlement (HE) which seriously reduces the strength of metals in extended contact with hydrogen. In order to greatly improve public confidence in the safety of hydrogen fuel, to address the technical issues, and thus facilitate the rapid commercialisation of hydrogen powered road transport, this project will develop a technology that will detect leaks and structural weakening of containment vessels caused by HE. This will prevent catastrophic failure of vessels which can actually occur before even small leaks arise. Particularly, the project goal is to develop novel tangential neutron radiography and acoustic emission (AE) techniques in combination for the reliable and cost effective continuous monitoring of the integrity of hydrogen storage tanks at central depots, service stations and on vehicles i.e. at every point of hydrogen storage along the supply chain from the production plant to the fuel tank on a hydrogen
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Soft Robotic Human-Machine Interfaces for Rehabilitation' to be submitted under Horizon 2020.

assistant: **Abstract**

Soft Robotics is an emerging technology that bridges the gap between humans and potentially harmful robots by developing devices, which are intrinsically safe to interact with. Former studies on Soft Pneumatic actuators (SPAs) show that they can be used for fine manipulation of fragile environments including interaction with living beings for rehabilitation purposes or as wearable devices for humans. The modeling and control challenges involving early designs of SPAs remain unanswered and hinder the application spectrum of such potentially disruptive innovation. Given the flexibility and scalability of SPAs, they can be also used as haptic devices in distributed surfaces.  The development of these technologies has been limited to testbench prototypes and their integration into a single platform for sensing and actuating at different scales has not been successfully implemented yet. To address this need, we propose the design and control of Soft fluidic actuated interfaces for Human-Machine interaction for rehabilitation devices. The development of scalable interfaces require a novel approach of actuation and sensing co-design for variable impedance devices in contact with humans. Besides representing a step forward in the applicability of the Soft Robotics concept, the devices can also provide an intrinsically safe solution for rehabilitative robotics to address the challenge of physical interaction. Through this project, the ER will reach a level of maturity on technological aspects in this rapidly growing research field. The proprietary microfluidic control developments at Elvesys will be feeding directly the advancement of this research. Also, the ER will benefit from entrepreneurship skills specific to SME environments, including market research, product valorizatio
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Intelligent in-vehicle terminal for multimodal flexible collective transport services' (INVETE).

assistant: **Concept**

In previous international R&D projects on flexible collective transport services, like SAMPO and SAMPLUS, the need for an intelligent In-Vehicle Terminal (IVT) for these services was identified. The INVETE project will specify, develop and validate a modular multi-application intelligent IVT, which responds to the user needs of the driver and the operational requirements of bus and taxi companies. By integrating new and existing on-board communication and location devices with the control centre, the IVT will allow the improvement of the quality and the reliability of the transport services provided to citizens. The provision of an affordable IVT with open software interfaces will allow market opportunities to be maximised. The IVT will be demonstrated and validated in the INVETE Demonstration Project (IST-1999-70311).Objectives:The aim of INVETE is to specify, develop and validate a modular intelligent in-vehicle terminal (IVT). The IVT can be used for different transport services i.e., regular and flexible collective transport and in different transport modes e.g., bus and taxi. The IVT is designed to operate in different communications environments like GSM and private radio network (PRN). The multi-application IVT is based on identified needs from users, the ITS environment, and the different transport services and operators. The IVT is inter-operable with other on-board devices. The provision of an affordable IVT with open software interfaces will allow extended market opportunities for suppliers and transport operators. There will be 30 IVTs designed and prototyped. Communication protocols and software for flexible collective transport services will be developed to support the full utilisation of the IVT.The IVT and the IVT services will be validated in real opera
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Chip-based nanoscopy: an affordable, multi-modal and high-throughput super-resolution imaging platform' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

The invention of optical nanoscopy is about to revolutionize several disciplines and it was awarded with a Nobel Prize in Chemistry in 2014. It is widely believed that a majority of existing optical microscopes will be replaced by an optical nanoscope. Unfortunately, the potential of the such a revolution and its widespread adoption are severely obstructed due to limitations of present day nanoscopy solution, i.e. system complexity, high cost and low throughput. In my ERC project, I have developed compact photonic chip-based optical nanoscopy, that can increase the throughput of convention optical nanoscopy by a factor of 100 times. The sample is placed on top of a photonic chip, capable of both holding and illuminating the sample, enabling to acquire super-resolved images. Photonic-chips can be retrofitted to an existing standard optical microscope converting it to high-resolution nanoscope. By way of analogy, moving from current super-resolution microscopy to chip-based nanoscopy will be as transformational as the move from main-frame computers to mobile phones. This is indeed a disruptive technology enabling widespread penetration of affordable chip-based optical nanoscopes. In ChipNano, the overall aim here is to bring the technology closer to the market by making the invention more commercially viable by a) co-operating and possibly setting-up business contract with the industrial partners on chip-production b) obtaining user feedback from key opinion leaders in Europe; c) consolidating business case to attract long-term venture funding in close cooperation with a university spin-off.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'DC for European Union'.

assistant: **Objectives**

Climate neutrality requires the cost-effective and reliable integration of large amounts of renewable energy sources in the power system, leading to the need of wheeling large amounts of power over long distances. HVDC and DC technologies are the most suitable choice to flexibly integrate remote energy sources in a reliable and cost-effective manner. To boost the development of DC technologies, the SET Plan Implementation Working Group on HVDC and DC technologies (DC IWG) has been established, with the goal of delineating a roadmap for the growth and deployment of HVDC and DC technologies over the coming years, through identifying the research and innovation priorities and enhancing the cooperation, collaboration, and coordination between the SET Plan countries. The current organisational support to the DC IWG is based on voluntary work from the members. DC4EU coordination and support action is designed to facilitate the work of the DC IWG and achieve its outcomes and to ensure the information exchange with the SET Plan. To accomplish this, DC4EU will provide organizational and administrative support to the DC IWG, as well as coordinate and communicate with relevant parties, stakeholders, and initiatives. Moreover, DC4EU aims to disseminate and exploit the outcomes of the DC IWG for wider adoption of the IWG outcomes. Additionally, the project seeks to initiate societal engagement to raise the awareness about the significance of DC technologies. By doing so, DC4EU will results in: (1) updating the implementation plan for HVDC and DC technologies to meet the future requirements/needs, (2) enhancing coordination between DC IWG members and between the DC IWG and the SET Plan office, (3) learning from first movers, which refers to the ability of gaining insights and knowled
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'Improving software products quality through the use of metrics'.

assistant: **Concept**

Quality requirements of industrial software are very high and the correctness of the source code is of great importance for this purpose. Traditionally, the correctness of a program has been checked through an exhaustive set of test cases that usually consider the program as a black box. It is well known that it is impossible to check the whole behaviour of the program through exhaustive tests, so an static analysis of the source code at an early stage can be of great help in order to pay special attention to those parts of the source code that are specially complex or not well written. The objective of QUALIMET is to improve this software development process, introducing a set of style norms to be used when coding in C++, and a set of metrics to be used on the source code in order to check its quality.THE EXPERIMENTThe QUALIMET experiment will consist on the introduction of a methodology for analysing the correctness of the source code. This experiment will be carried out in the context of the development of a small distributed control system based on a PC network for process monitoring and control. The development in C++ of this small tool, following an object oriented methodology, will be the baseline project. The different aspects of the methodology that will be covered under the experiment are the following:Definition of a set of style norms to be used when coding in C++.Selection of software quality measurement tools suitable for their use in C++ source code.Selection of a set of metrics to be applied on the C++ source code.Usage of the selected style norms and metrics for C++ in the baseline project's source code.The conclusions obtained through the experiment will allow to refine its results in order to be used in future applications.ROBOTIKER employs 99 people,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Innovative Flavonoid-based Nanoparticles (Flav-NPs) to Fight Against Colorectal Cancer (FLAVCAN)' (Flav-NPs).

assistant: **Innovation**

Colorectal cancer is among the most lethal and prevalent malignancies in the world. Current treatment has limitations, such as adverse effects, drug resistance, metastasis, and recidivism. Flavonoids such as Apigenin, Epigallocatechin-3-gallate, and Quercetin have demonstrated anticancer effects and alternatives for new treatments. Flavonoids can suppress tumor growth, induce apoptosis, inhibit angiogenesis, and modulate cellular signaling pathways in development and progression. Multiple flavonoids administrated simultaneously potentially enhance their biological activities, improving the local effect and instigating a synergistic inhibitory effect on cancer cell viability, increasing apoptosis, decreasing proliferation, and causing the arrest of the chemoresistant cells. Flavonoids are challenging to use orally for therapeutic purposes due to their molecular instability and insufficient delivery to the distal portions of the intestine. This project uses a microfluidic platform to identify a potent flavonoid combinatory nanoformulation-based polysaccharide (cellulose derivates) for oral administration. Flav-NPs can enhance chemical stability, accurately control the release of flavonoids, and potentially overcome digestion factors. Flav-NPs can impact multidimensional mechanisms of anticancer action to more effective therapeutic, reduced cellular proliferation, and invasiveness at different cancer stages. Pre-clinical methodologies will be applied to characterize, and stability in vitro digestion will be evaluated. Spheroid and organoid models will determine cell viability and anticancer efficacy. A gut-on-a-chip model will also be developed to observe the effects of Flav-NPs in a simulated intestinal microenvironment tumor. The simplicity of manufacturing and the feasi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'FUNCTIONAL BIOLOGY AND ECOLOGY OF PLANKTONIC MARINE FUNGI – Revealing the mechanistic basis of the roles of mycoplankton in the marine carbon cycle' in the context of a Horizon 2020 call.

assistant: **Objectives**

Marine planktonic fungi (mycoplankton) have been largely ignored compared to other plankton groups, such as phytoplankton, especially the roles that they fulfil in marine ecosystems. My research has shown that mycoplankton are a major structural and functional component of coastal ecosystems that have been almost completely overlooked. I have shown that mycoplankton are a substantial proportion of plankton biomass and that saprotrophic mycoplankton are active in coastal ecosystems. Mycoplankton are also a major plankton group in the open ocean and dominate on marine snow particles. These studies demonstrate that fungi have potential roles in the marine carbon cycle including the biological carbon pump. The absence of fungi within a general view of the structure and function of the marine carbon cycle, including a lack of mechanistic understanding of saprotroph functional biology and ecology, represent major knowledge gaps in our understanding of marine ecosystems that must urgently be addressed. MYCO-CARB will address these knowledge gaps through an innovative programme of research. Research cruises at established marine observatories will make an unprecedented assessment of active mycoplankton diversity and abundance across a range of ecosystems; from surface coastal waters to the deep open ocean. Innovative approaches, including molecular ecology tools and ecosystem modelling, will establish the impact of fungal saprotrophs on the marine carbon cycle. A culture collection will be developed, informed by the field-based surveys of natural assemblages to produce ecologically-relevant model fungi. Complementary culture-dependent and -independent systems biology methodologies will determine the underpinning biological machinery of saprotrophic marine mycoplankton. Through
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Trophodynamics of Organic Pollutants Studied by Compound-Specific Isotope Analysis' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Endocrine disrupting chemicals (EDCs) and emerging pollutants are of global concern, yet their potential to become biomagnified in the aquatic food webs has not been determined. ‘TOP’ aims to tackle this question by coupling the analyses of pollutants, lipid content, trophic position, and compound-specific stable isotope analyses (CSIA). The objectives are to develop and validate CSIA methods; to refine and apply sampling, extraction and analytical methods to target pollutants in water, sediment and biological samples; to perform field sampling in the UK and China followed by chemical and isotopic analyses; and to predict the transport and fate of the target compounds in the aquatic systems using a multi-compartment (water-plankton-invertebrates-fish) model. Both the host institute and fellow have a proven track record in pollutant fate studies and isotope analysis. TOP therefore supports the collaboration and development of dynamic world-class human resources in the European research system. This proposal consists of a scientific project and scientific and complimentary training. The fellow will receive scientific training to acquire further skills in environmental investigations and data analyses; to design, conduct and report on cutting edge research on emerging pollutants; and to develop novel CSIA approaches. Complementary training will involve the fellow learning and practising transferable skills, e.g. presentation, project management and grant applications, as part of his career development plan. The objectives will be achieved through careful planning and management of the fellowship. The proposed scientific project is timely and appropriate methodology has been established. Novel and state-of-the-art techniques will be used. The supervisors and the fellow have
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Development and application of transposons and site-specific integration technologies as non-viral gene delivery methods for ex vivo gene-based therapies' will create measurable scientific, societal and economic impact aligned with Sixth Framework.

assistant: **Impact**

Considerable effort has been devoted to the development of gene delivery strategies for the treatment of inherited and aquired disorders in humans. Ex vivo gene therapies are based on removing cells from a patient, introducing a therapeutic gene construct into the cells, and implanting the engineered cells back into the patient. Currently, both viral and non-viral methods are used for gene delivery. Viral vectors are efficient in gene transfer, but their use raises serious safety concerns. Non-viral methods are usually safer but less efficient in providing long-term therapeutic transgene expression. Transposable elements can be considered as natural, non-viral delivery vehicles capable of efficient genomic insertion.In this project, novel gene transfer technologies will be established by developing transposon vectors that mediate efficient and targeted integration of therapeutic genes into the genome. Therapeutic gene constructs will be made in transposon vectors, and delivered into cells ex vivo, using cutting edge non-viral nucleic acid delivery methods. Application of reversible implantation systems (collagen implants, skin biopumps, and encapsulated cells) will be explored. Animal disease models will include copper metabolism diseases, anemia, hypercholesterolemia, bleeding disorders, chronic grnulomatous disease and neurological disorders. Genomic insertion, transgene expression and phenotypic correction will be investigated. Safety issues of transposon vector administration and genomic integration will be addressed. The involvement of three SMEs will mobilise industrial know-how and technology. This project will develop, test and apply new therapeutic tools for somatic gene therapy as an alternative to currently used viral and non-viral technologies, and will have