RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Adaptable Multiflow Diagnostic Platform to Genetically Identify Drug Resistant Infection' (2014-2020), addressing dissemination and exploitation.

assistant: **Impact**

Tuberculosis (TB) killed 33 million people worldwide in 2000-2015 and infects an estimated ¼ of the world population. Drug-resistant forms of TB are flourishing at an alarming rate due to faulty diagnosis and widespread prescription of incorrect antibiotics. Rapid and accurate detection of multi-drug resistant (MDR) strains is urgently needed to effectively treat patients and prevent spreading of untreatable TB forms. Simple, low cost diagnostic tools are needed to enable point-of-care testing in low- and mid-income countries.  mfloDx is a low-cost, simple diagnostic platform that can identify close to 100% of drug resistant TB cases. Pilot tests of the first product, miniMDR-TB, showed the efficiency and specificity to be 92-96% in agreement with that of another molecular test recommended by the World Health Organization. Our next-generation mfloDx products, MDR-TB and MDR-TBplus, are expected to have close to 100% MDR-TB identification power. The low cost of mfloDx tests will enable market uptake in highly afflicted developing countries, and thereby help to stop the loss of life, the spread of antibiotic-resistant infections, and prevent unnecessary costs.   Projected global expenditure on diagnosis and treatment of TB will reach €983 billion between 2015-2030. The addressable market for TB diagnostics is projected to grow to €3.1 billion by 2024. Available commercial diagnostics for MDR-TB often deliver incomplete diagnoses and require long lag times, costly equipment (€15-32K), and highly trained personnel to recommend prescriptions. As a result, less than one-third of new TB patients undergo testing to determine appropriate antibiotic treatments. Our estimates suggest that mfloDx would reduce the treatment costs per MDR-TB patient by tens of thousands of euros and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Colloidal Quantum Dot Molecules for Display Applications' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

Displays are all around us. They are in smartphones, laptops, TVs, and cars and have become entwined in our everyday life with new features being added, such as the Augmented Reality technology. The market strives for constant improvement in display technology performance, with better colors, thinner formats, and new functionalities. The market share of Quantum Dot (QD) displays is constantly growing because of the pure colors emitted from colloidal semiconductor nanocrystals which enable a more vibrant and colorful viewing experience. Yet, the current QD displays are inefficient, not bright enough, consume relatively high energy, and have limited pixel resolution. In the ERC grant we have developed a generic method of binding and fusing two QDs into a new class of CQDM (Coupled QD Molecules). This opened the path for the synthesis of novel CQDMs with varying semiconductor nanocrystal monomers (e.g. size, shape, and composition). Herein, we propose to develop this concept towards the commercialization of CQDMs as unique and novel materials for innovative high quality displays. Such CQDMs, with two different cores each tuned to a different color, have the ability of dual-color emission, red and green, which can be controlled electrically. A pixeled layer of these novel materials can be inserted as the emissive layer in any of the present- and future-day display technologies, providing brighter and more stable and efficient displays alongside a much simpler production process compared to patterned separate red-green QD pixels. Preliminary discussions with leading companies and investors have highlighted this potential signifying that the development of this technology can be of significant industrial value. We plan to pursue this within the ERC-PoC grant by two main work
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Perspective and the Self in Natural Language'.

assistant: **Concept**

This project investigates the encoding of perspective in natural language, with particular emphasis on the semantics of attitude reports. Data from linguistic fieldwork and psycholinguistics are employed. The topic is closely connected to attitudes de se - thoughts, expectations, hopes and the like that are inherently first personal, as with 'John claims to be a good semanticist'. The hypothesis to be investigated is that linguistic reports of attitudes de se are a special case of perspectival language. We investigate to what extent the formal tools that have been developed for the analysis of attitudes de se can be applied to other perspectival phenomena. Our expectation is that some perspectival language will be shown to call for a distinct analysis from those currently available for attitudes de se. The challenge would then be to develop novel formal tools with which to model these expressions. The results are expected to have consequences for not only theoretical linguistics, but also philosophy of language and cognitive science.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Foresight for regional development network' (FOREN).

assistant: **Innovation**

The aim of this proposal for a thematic network is to gather two communities of policy research one in Foresight activities and the other one on in Foresight activities and the other one on Regional Development. The network aims to create a forum where participants can interchange experiences of best-practice approaches" in the two fields, and bridge the existing gap between their respective communities. The final aim is to identify "good practices", which could be used to guide and inform specific Foresight activities at regional level in different parts of Europe. The project is intended to generate knowledge, and to lay foundations for concrete pilot projects, between policy researchers, policy makers and other players (regional)."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Neural Mechanisms and Non-invasive Deep Brain Stimulation of Mood and Well-being', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Our expectations about the world shape our mood and well-being. In extreme contexts, mood can become pathologically depressed as in mood disorders or dementia. Recent studies have begun to suggest a mechanism for how expectations (and their violation) impact human moods. Unfortunately, this mechanism relies on correlational studies since we currently lack tools able to directly manipulate these circuits in healthy humans. UltraDeepMood will combine cutting-edge ultrasound stimulation with imaging and computational modeling to determine the hypothesis that human moods can be changed by modulating expectation signalling in deep brain subcallosal cingulate circuits.UltraDeepMood will overcome the current major limitations hindering our understanding of mood circuits in humans. First, the lack of non-invasive tools to modulate activity deep in the healthy brain: by using focused transcranial ultrasound stimulation (TUS), a technique I have pioneered in deep primate areas, I will non-invasively manipulate human circuits to causally establish their role in mood. Second, by using TUS to modulate dopamine-projecting areas, I will directly modulate learning and decision processes in the striatum and disentangle them from those underlying mood and well-being in subcallosal anterior cingulate cortex.UltraDeepMood has three key aims: (1) dissociate the contribution of gray versus white matter TUS to mood connectivity; (2) combine TUS with fMRI and computational models to determine the role of deep cingulate circuits to mood; (3) directly manipulate related circuits of learning and decision-making.UltraDeepMood will reveal a novel mechanistic insight into the circuits of moods and well-being in the healthy brain. This non-invasive approach will open an unprecedented avenue in shapin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Many-Electron Wigner Molecules: 3-D quantum dots' in the context of a Seventh Framework call.

assistant: **Objectives**

At the outset of the 21st century, and after eighty years of the advent of quantum mechanics, theoretical studies on small species still raise a lot of interest as foundations upon which research on methods for treatment of general systems is based. It is often believed that the gap which separates the exactly treatable models from the experimental results works against multidisciplinary character of research that is sought in modern science. However, in the case of quantum dots this common belief does not reflect reality, as these systems can have their structures theoretically analyzed in an exhaustive way and at the same time they are of great experimental relevance. Harmonium atoms are an especial kind of 3D quantum dots in which the central Coulombic potential of nuclear attraction is replaced by a harmonic one. For a small number of atoms these systems are analytically solvable or quasi-solvable. In the recent years there has been a renewed interest in harmonium atoms, particularly in the so-called Wigner molecules.   In this project we study several harmonically confined clusters, and few-electron harmonium atoms with the aim to understand the electronic structure and the energetics of these species, especially at strong correlation limit (Wigner molecules) in order to provide guidance for future experimental research on quantum dots and assessment of their usefulness as benchmarks for DFT, DMFT and other electronic structure methods.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Harvesting dark plasmons for surface-enhanced Raman scattering' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Metal nanostructures show pronounced electromagnetic resonances that arise from localized surface plasmons. These collective oscillations of free electrons in the metal give rise to confined electromagnetic near fields. Surface-enhanced spectroscopy exploits the near-field intensity to enhance the optical response of nanomaterials by many orders of magnitude. Plasmons are classified as bright and dark depending on their interaction with far-field radiation. Bright modes are dipole-allowed excitations that absorb and scatter light. Dark modes are resonances of the electromagnetic near field only that do not couple to propagating modes. The suppressed photon emission of dark plasmons makes their resonances spectrally narrow and intense, which is highly desirable for enhanced spectroscopy as well as storing and transporting electromagnetic energy in nanostructures. The suppressed absorption, however, prevents us from routinely exploiting dark modes in nanoplasmonic systems.I propose using spatially patterned light beams to excite dark plasmons with far-field radiation. By this I mean a beam profile with varying polarization and intensity that will be matched to the dark electromagnetic eigenmode. My approach activates the excitation of dark modes, while their radiative decay remains suppressed. I will show how to harvest dark modes for surface-enhanced Raman scattering providing superior intensity and an enhancement that is tailored to a specific vibration. Another feature of dark modes is their strong coupling to the vibrations of nanostructures. I will use this to amplify vibrational modes and, ultimately, induce phonon lasing. The proposed research aims at an enabling technology that unlocks a novel range of nanoplasmonic properties. It will put dark plasmons on par wit
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Breaching the protective cancer stroma with radiotherapy-responsive liposomes' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

Liposomes have been the most successful type of nanomedicine for cancer patients, playing a leading role in improving the tolerability of chemotherapeutics. However, to advance the success of liposomal drug delivery and cancer treatment, new approaches to physically trigger drug release in cancer tissues and increase the permeability of the protective cancer stroma are needed. This project will investigate whether radiocatalytic nanomaterials can be integrated in liposomes for spatiotemporal-controlled drug release, the alleviation of cancer desmoplasia, and improved efficacy of co-encapsulated drugs. Liposomes will be composed of oxidation-susceptible phospholipids that encapsulate hydrophilic drugs in their aqueous core. Radiation-absorbing nanomaterials will be included in the liposomes to produce high levels of reactive oxygen species when activated by X-rays. This will oxidize the liposomes and facilitate the release of the encapsulated drugs. Simultaneously, the cytotoxicity of the oxidants is expected to reduce the high cell densities in the tumor periphery, enabling the therapeutics to deeply permeate the cancer tissues following their release. This customizable strategy will be developed in the context of pancreatic cancer, a chemoresistant form of cancer with poor survival rates. This project develops a multidisciplinary approach to investigate the physicochemical mechanisms of radiotherapy-induced drug release, adaptive optics microscopy to study tissue permeability in 3D cultures of desmoplastic pancreatic cancer, and multimodal in vivo imaging to uncover the therapeutic potential and mechanisms. Radiotherapy-controlled drug release from liposomes is a ground-breaking novel concept, and its capacity to increase cancer tissue permeability has never before bee
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Monitoring shifts in health sector policies in south asia' to be submitted under Fifth Framework.

assistant: **Abstract**

The concerted Action proposes to develop a net-work of South Asian and European scholars that would take up policy issues of common interest for exploration, analysis and exchange of ideas with the purpose of intervening in policy debates and generating public aware-ness regarding health sector reforms as influenced by Structural Adjustment Programmes . This interaction would be around the policies frequently associated with Health Sector Reforms such as cuts in investment in Public Sector etc.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Supercritical CARbon dioxide/Alternative fluids Blends for Efficiency Upgrade of Solar power plants' (SCARABEUS).

assistant: **Innovation**

The main objective of the SCARABEUS project is the reduction of the CAPEX and OPEX in concentrated solar power technologies by about 32% and 40% respectively, leading to a final cost of Electricity below 96 €/MWh (lower than 30% of the actual value) through an innovative power cycle based on CO2 blends. This cost reduction will be able to close the gap between CSP and other renewable technologies. This project fits in the call ""New cycles and innovative power blocks for CSP plants."" as a brand new power cycle concept will be developed. With respect to state-of-the-art sCO2 cycles, the addition of small quantities of selected elements to pure CO2 (i.e. inorganic compounds and fluorocarbons), known as CO2 blending, can increase the CO2 critical point allowing the adoption of condensing cycle even in typical CSP plant locations. Condensing sCO2 cycles have higher thermal-to-electricity conversion efficiency with respect to conventional steam and sCO2 cycles.In addition, higher maximum operating temperature with respect to steam cycles can be adopted with further efficiency increase. The combination of these two aspects enables drastic reductions of the levelised cost of electricity In the project, CO2 blends stable at temperatures up to 700°C (which corresponds to 100°C above current CSP maximum temperatures) and with a pseudocritical temperature of about 50°C will be investigated. A preliminary screen was performed identifying some potential candidates (i.e. TiCl4). Assuming the simple cycle configuration, the TiCl4-blended CO2 outperforms the cycle using pure CO2 by 5% points at 700°C . When using the advanced sCO2 cycle, the efficiency gain is reduced to 2% points, but with significant cost savings. The proposed CO2 blend will be tested in a loop at 300 kWth scale wit
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Distributed Signal Processing Algorithms for Chronic Neuro-Sensor Networks' (2014-2020).

assistant: **Concept**

The possibility to chronically monitor the brain 24/7 in daily-life activities would revolutionize human-machine interactions and health care, e.g., in the context of neuroprostheses, neurological disorders, and brain-computer interfaces (BCI). Such chronic systems must satisfy challenging energy and miniaturization constraints, leading to modular designs in which multiple networked miniature neuro-sensor modules form a ‘neuro-sensor network’ (NSN).However, current multi-channel neural signal processing (NSP) algorithms were designed for traditional neuro-sensor arrays with central access to all channels. These algorithms are not suited for NSNs, as they require unrealistic bandwidth budgets to centralize the data, yet a joint neural data analysis across NSN modules is crucial.The central idea of this project is to remove this algorithm bottleneck by designing novel scalable, distributed NSP algorithms to let the modules of an NSN jointly process the recorded neural data through in-network data fusion and with a minimal exchange of data.To guarantee impact, we mainly focus on establishing a new non-invasive NSN concept based on electroencephalography (EEG). By combining multiple ‘smart’ mini-EEG modules into an ‘EEG sensor network’ (EEG-Net), we compensate for the lack of spatial information captured by current stand-alone mini-EEG devices, without compromising in ‘wearability’. Equipping such EEG-Nets with distributed NSP algorithms will allow to process high-density EEG data at viable energy levels, which is a game changer towards high-performance chronic EEG for, e.g., epilepsy monitoring, neuroprostheses, and BCI.We will validate these claims in an EEG-Net prototype in the above 3 use cases, benefiting from ongoing collaborations with the KUL university hospital. In