RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Exploiting Modular Biochar and board production plants to locally transform waste from traditional agrifood, feed and forestry industries into bio-materials with rEgional DEmanD.' (EMBEDED) targeting Horizon Europe.

assistant: **Abstract**

The EMBEDED project aims to demonstrate alternative business models in 36 months by transforming waste from Europe traditional agrifood industries into biochar and construction boards, with a long-term carbon sink effect and short resilient value chains. The validation of the km.0 application of biochar on primary producer plantations and the regional market characterization will be conducted. Valorisation streams aim to combine marginal revenues from mainstream residues (olive pomace, olive stones, grape mark) with overlooked or underutilised ones (cork bark left on field, press-cake from fresh grass, grape stems), with five demonstration pilots planned in Portugal, Ireland, Spain, and Czech Republic. Four of the pilots will have pyrolysis for the manufacture of biochar, using a modular method that fits pre- and post-conditioning phases into a single-maned portable unit. In two of the pilots, extractive methods aimed at bio-active chemicals will be evaluated to determine the added benefit of a cascade valorisation. Using a modular but stationary pilot, the Board production plant will capitalize on the cork outputs geographical. The consortium comprises 14 participants, comprising 5 SMEs and 1 LE that includes 2 technological developers and many influential figures in the agri-food industry of each designated region. In order to implement technology replications and technical transfer using the multi-actor strategy, the EMBEDED project will use 15% of the requested grant (750 k€) as financial support.


**Keywords:** Biochar, pyrolysis plant, fertilizer, feed ingredient, cork waste, bioactive compounds
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Council of Coaches'.

assistant: **Innovation**

Despite the proliferation of ICT solutions for personalized healthcare, there is still no easy way to provide older adults with integrated coaching services. Council of Coaches (COUCH) introduces a radically new virtual coaching concept based on multiple autonomous, embodied virtual coaches, which form together a personal council that fulfills the needs of older adults in an integrated way. Each Coach has his own expertise, personality and style of coaching; they might not always agree with each other, but they all share a single goal: to support you across every aspect of well-being, including physical, social, cognitive and mental support. The Council members listen to you, inform you, help you to set personal goals and inspire you to take control of your health. Give the council your thoughts, or listen and observe how the individual Coaches exchange their views on numerous issues. Apply your new skills in daily life and if the need arises, contact any of the coaches anytime, anywhere.COUCH will be empowered by a novel Open Agent Platform, providing core functionalities for the development and deployment of Coaches, including technologies for non-obtrusive interactions between the user and the Coaches. To this end, leading edge spoken dialogue interaction technologies will be provided as embodied conversational agents that will join in conversations with the user. The platform will not be confined to a constrained number of Coaches – rather it will enable developers and innovators to introduce new Coaches that provide additional knowhow and services. Hence, COUCH will enable a new virtual coaching ecosystem, bringing together healthcare services providers with innovators to implement novel ideas. Plans for the sustainability and wider use of its paradigm will be base
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'The evolutionary history of oncogenic and non-oncogenic papillomaviruses' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Certain papillomaviruses (PVs) are a major public health concern as in humans they are responsible for virtually all cases of cervical and anal cancer, and for a fraction of cancers on the penis, vagina, vulva and oropharynx. But oncogenic PVs are actually an unfortunate exception, as most PVs cause asymptomatic infections, and a few cause benign, wart-like lesions. Despite the efforts directed towards the understanding of the different clinical manifestations of infection, our knowledge on PV evolution remains fragmentary.Oncogenic human PVs arose recently, after acquiring the E5, E6 and E7 genes. The integration of the E5 proto-oncogene in the ancestral AlphaPV genome allowed viruses to evade host immune response. Thereafter E6 and E7 acquired the ability to target essential tumor suppressor proteins, paving the way for carcinogenesis. Tracking the evolutionary history of the E5, E6 and E7 oncogenes will thus help understand the emergence of oncogenic human PVs. Regarding the deep roots of PVs, small DNA viruses may share a common ancestor as they encode proteins sharing similar functions and domains, but their evolutionary origin is still an enigma.Here I propose to apply an evolutionary medicine approach, combining in silico and wet-lab approaches, to study key events that occurred during PV genome evolution. We will go back into history and study how and when certain PVs became oncogenic. We will resurrect the ancestral oncogenes, and experimentally test hypotheses about the function of the resurrected proteins in different environmental contexts. We will then generate a comprehensive scenario modelling the appearance of the modern PV genome and the emergence of the oncogenic phenotype of certain PVs. Finally we will explore the relationships between small DNA viru
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'The Value of Information and Choice to Improve Control.' (VINCI).

assistant: **Concept**

Predictions and control about impending action and rewards or punishments require accumulating information about our environment and ultimately choosing the action that will maximize reward. Therefore, contexts containing a large amount of information about the environment and with several available options to gather reward or avoid punishment are generally preferred by agents. Because information intake and choice seeking are so important for survival and well-being, they can be considered as cognitive rewards, i.e. a higher order form of reward not directly related to immediate satisfaction like food or water. This proposal seeks to understand the neural mechanisms involved in the encoding of these cognitive rewards. How cognitive rewards like information and choice availability are encoded and manipulated in the brain remains a major unanswered question. Evidence suggests that cognitive rewards may be encoded by the dopaminergic system in a way similar to basic rewards like food or water.  In contexts where the amount of basic reward will be equal, I will train monkeys to perform a task where they will get either more choice or more available information related to the type of upcoming basic reward. I hypothesize that monkeys will prefer conditions where more choice or more information are available compared to condition where these variables are lacking. Using simultaneous high-density electrophysiological recordings, we predict that midbrain dopaminergic neurons will reflect these preferences. By using fiber photometry targeting specifically dopaminergic neurons, we will also investigate how the neural signal related to cognitive reward are transmitted from midbrain dopaminergic neurons to the dorsolateral prefrontal cortex and the striatum, two structures receivin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Assembly Tooling for the Fast Rotorcraft Project', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

The objective of the project is to get a complete set of assembly and maintenance tooling, including auxiliary tooling. Due to the tight tolerances required in aeronautical industry, Some assembly jigs will be equipped with an optical structured light measure system that will allow the set up of the tooling and the position verification of the parts during assembly with tolerances equal or under 0.1 mm. The use of this kind of systems are spearhead in the field of precision measurement and the advantages against currently measurement systems, as laser tracker, will be shown in following paragraphs. In addition, optical systems are becoming the preferred measurement systems in automatized assembly jigs which will be the step forward in the aeronautical assembly lines.


**Keywords:** assembly tooling, Maintenance Tooling, Structured Light
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Do AI generated outputs have contents?'.

assistant: **Concept**

This project asks: do the outputs of machine learning neural net AI systems (henceforth, ‘AI systems’) have contents i.e., do they have meanings, express propositions, or represent objects of the world? It approaches this larger question by dividing it up into three smaller, closely aligned questions: (a) Are mental capacities necessary for producing outputs with content? (b) What does it take for an entity to have those capacities? and, (c) Do AI systems have those capacities? These foundational questions underpin and support several further investigations concerning the potential and threats of AI systems, including their role in spreading propaganda, disinformation, and fake news, and the question of whether AI systems can develop their own language. The project’s main innovation is its humanistic approach — its investigations are guided by the hypothesis that any philosophically interesting notion of ‘content’ must be comprehensible, and apply to human speech, images, and artefacts. The project combines the expertise of the Experienced Researcher (ER) on the semantics of natural language expressions with the current research of the supervisor (Matti Eklund) on ‘alien’ languages (i.e., languages semantically and structurally different from human languages). The project will greatly enhance the ER’s career prospects because of the training and mentorship that the ER will receive as part of the project, and because of the close synergy between the ER’s research focus, the supervisor’s internationally renowned expertise on semantics and metaphysics, and the host organisation’s (Uppsala University) strengths in pragmatics, artificial intelligence, and computational linguistics. Conversely, the ER’s research will enrich and generate substantial added value for the host in
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Cytonuclear coevolution and speciation genomics in natural populations' in the context of a Seventh Framework call.

assistant: **Objectives**

My project will investigate the interactions between the mitochondrial and nuclear genomes. Proteins encoded by both genomes are required for cell respiration, the main source of energy production in eukaryotes. Selection is strong for optimal function of cell respiration, leading to coadaptation of mitochondrial and nuclear genes (“cytonuclear coevolution”). Experiments have show that the breakup of such coadapted gene complexes can lead to hybrid breakdown, which may reduce gene flow between populations and generate reproductive isolation. Hence, cytonuclear coevolution can be important in generating intraspecific genetic diversity. I will use a threefold approach to evaluate the importance of cytonuclear coevolution in natural populations, using a hybrid zone in the black-tailed brush lizard as a model system. Firstly, I will investigate cytonuclear coadaptation at the nucleotide level by studying sequence variation in interacting genes within and between hybridizing populations. Secondly, I will study the fitness consequences of cytonuclear coevolution by comparing enzyme activity of coadapted versus maladaptive gene products. Finally, I will evaluate the potential for cytonuclear coevolution to generate reproductive isolation by using single nucleotide polymorphisms (SNPs) and nuclear intron sequences to evaluate nuclear genomic divergence. This research will provide a fundamental contribution to understanding reproductive isolation and genetic diversity in natural populations.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'BE a citizEn Scientist'.

assistant: **Innovation**

"Be a citizen scientist""will be the slogan of European Researchers' Night organized by Frascati Scienza in 36 Italian cities.59 partners - research centres, educational institutes, universities, cultural and scientific centres and associations of science communication -  will work together with citizens to increase the spread and relevance of the message that science and the researchers' work have to be actively participated by the society. Besides the hundreds science communication activities organized and promoted by Frascati Scienza in the previous 12 European Researchers' Night, some events will be designed to specifically involve the public, and in particular young people, to be co-protagonist of the manifestation. This will be the power of the Frascati Scienza' European Researchers' Night, that want to involve citizens not only in the debate about science but thrilling them in directly experience the discovery of science.Citizens will participate in mini citizen science projects, aiming to valorize the Italian cultural and scientific heritage, working together with researchers and in strong connection with the cities involved, enhancing the role of the researchers for the society and the relationship with policy makers and stakeholders.""


**Keywords:** European Researchers' Night, value of research, young people, citizen science, impact assessment
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Novel avenues of action for a hallmark disordered protein of Parkinson's disease' to be submitted under Horizon 2020.

assistant: **Abstract**

Alpha-synuclein (aSN) is an intrinsically disordered protein (IDP) expressed by neurons, and well-known to aggregate in so-called Lewy bodies (LB) that are a hallmark of Parkinson’s disease (PD) and other LB disorders. Despite extensive research, the mechanisms underlying its toxicity in these disorders still remains to be understood. In this project, I will determine whether aSN can interact with other disordered proteins in a novel, mean-field type interaction, focusing on the disordered loop of the neuronal plasma membrane Ca2+ ATPase (PMCA). I will study this using biophysical techniques, in particular NMR, ITC and SAXS/SANS. This project will improve the understanding of aSN and its interactions and has the potential to pave the way for new discoveries, especially in drug design. I will gain important experience in project design and management, a research network in Europe, and take a significant step towards independence. I will undertake this project at the University of Copenhagen in the research group of Professor Birthe B. Kragelund, an expert in the field of IDP research. The Kragelund group has recently joined the BRAINSTRUC Consortium: a group of researchers working on the structural characterization of neuronal proteins. Thus, they required a postdoctoral researcher with a strong background in neuroscience and structural biology. I was uniquely qualified to take this position as I have been working on neurodegenerative proteins for several years and structurally characterized the IDP associated with Huntington’s disease. Professor Kragelund has experience supervising productive postdoctoral researchers, an extensive European network, and has access to the state-of-the-art facilities necessary to complete this project. I have recently acquired preliminary
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'A biomimetic synthesis of Haouamine A and analogues' under Seventh Framework.

assistant: **Concept**

Haouamines A and B were isolated in 2003 by Zubia and co-workers from the Ascidian Aplidium haouarianum, collected off the coast of southern Spain. Haouamine A was found to exhibit selective cytotoxicity against a human colon cancer cell line (HT-29, IC50 = 0.1 µgml-1, 200nM). From a structural standpoint, these novel polycyclic alkaloid metabolites exhibit several fascinating features: both alkaloids feature an indeno tetrahydropyrimidine moiety that contains a diaryl quaternary center and anti-Bredt double bond. The tetrahydropyridine ring is fused to a highly strained 11-membered cyclophane ring system. In addition, NMR studies have shown that they exist in solution as a dynamic 2:1 interconverting mixture of stereoisomers generated either by nitrogen inversion or by atropisomerism of the biaryl unit. Of even greater import, the uniquely strained nature of the 3-aza-[7]-paracyclophane unit has been clearly revealed by X-Ray crystallography and the non-planar south-eastern aromatic ring is in fact so deformed that it exists in a boatlike conformation. The combination of interesting biological activity and novel chemical structure makes the haouamines attractive targets for synthesis.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Cold gases with long-range interactions: Non-equilibrium dynamics and complex simulations' (ColDSIM) under Seventh Framework.

assistant: **Objectives**

Cold gases of electronically excited Rydberg atoms and groundstate polar molecules have generated considerable interest in cold matter physics, by introducing for the first time many-body systems with interactions which are both long-range and tunable with external fields.  The overall objective of this proposal is (i) the development of theoretical ideas and tools for the understanding and control of non-equilibrium dynamics in these diverse systems and in their mixtures, including dissipative effects leading to cooling, and (ii) to analyse emerging fundamental phenomena in the classical and quantum regimes of strong interactions, leading to innovative simulations and experiments of complex classical and quantum systems. The project is divided into three parts, with strong overlap:1)  Rydberg atom dynamics: The study of complex open-system dynamics in gases of laser-driven Rydberg atoms, including the study of the effects and control of dissipation and decoherence from spontaneous emission in strongly interacting gases.2) Cooling of complex molecules in atom-molecule mixtures: The theoretical investigation of novel ways to perform cooling towards quantum degeneracy of generic, comparatively complex molecules, beyond bialkali ones, in mixtures of groundstate molecules and of Rydberg-excited atoms.3) Simulations of strongly interacting many-body systems at the quantum/classical crossover: Atomistic characterization of formation and dynamics of formation of strongly correlated phases with long-range interactions.For each of these subjects, the objectives are at the cutting edge of fundamental atomic and molecular science and technology.