RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Chemical Recycling for the New Plastic Economy' under Horizon 2020.

assistant: **Concept**

Global production for plastic has grown to over 300Mt/year and rising. However, only 14% of plastic packaging is collected for recycling, and plastic packaging with an economic value of €70-110 billion is lost annually to the economy after just a short use. The vast majority of plastic is still disposed of by incineration or landfill, with in excess of 8Mt leaking into the oceans each year. It is estimated that by 2050 there will be more plastic than fish in the ocean. Recycling Technologies Ltd. has developed a process that recycles end-of-life mixed plastic waste [MPW] into a commercially valuable hydrocarbon called Plaxx. The technology is capable of processing varied types of MPW. Plaxx produced by the process can be used as a substitute for Heavy Fuel Oil but with the advantage of being very low sulphur.However, rigid food containers and items such as drinks cartons etc., use laminates of differing polymers. The widespread use of dyes, fillers and other additives, alongside contamination from the contents of the original packaging, presents challenges for our process. Currently, our process is designed to process MPW with low levels of contamination. Capability to process a higher level of contamination through our process opens up markets 2-3 times bigger than at present. Therefore the aim of this project is to further develop the gas filtration system of the technology, and the recruitment of an Associate with the level of expertise to realise this innovation opportunity is therefore essential. During the project, the Associate will research on widely used gas filtration technologies and recommend the ones which are suitable and scalable for our process.The success of this project underpins RT’s vision - to establish a commercially attractive process that will ul
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Evolutionary Cellular Computing for Environmental Synthetic Biology'.

assistant: **Objectives**

This project will build living evolutionary cellular computers, and showcase them as intelligent bioremediation agents. Current synthetic genetic networks that perform human-defined computations must remain unchanged—as initially designed—in order to perform well. This is a problem, since biological substrate adapts and evolves, compromising durability, robustness, and computing power. We will exploit the intrinsic dynamic features of living systems. ECCO’s biocomputers will be able self-adapt and reconfigure at run-time. They will show unprecedented levels of robustness and efficiency—far beyond current technological limits. To this end, we will tackle intra-cellular evolvability and multi-cellular reconfigurability. At the intra-cellular level, we will upgrade current genetic circuitry with pre-defined mutation, evaluation and selection dynamics. Circuits will optimise themselves. At the multi-cellular level, we will design cellular consortia able to reconfigure its structure—therefore changing its functionality—according to environmental needs, thus adaptive. The ECCO project will integrate theoretical developments with in-vivo experimentation. The soil bacteria Pseudomonas putida will be used as a host to illustrate the capabilities of evolutionary genetic circuits. To demonstrate long-run efficiency, bacteria will be used to colonize the root of the plant Arabidopsis thaliana—a much more complex environment than the pristine laboratory conditions where circuits are often characterized. Reconfigurability will be achieved by building a multicellular computer able to switch between metal and aromatic removal circuits—two important pollutants. Evolution, adaptation and reconfigurability are elusive to conventional computers; conveniently, these are intrinsic properties
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'The carbon and nitrogen isotopic composition of organic matter in tropical lake as a record of environmental change' to be submitted under Fourth Framework.

assistant: **Abstract**

Research objectives and content The project will examine the stable carbon and nitrogen isotopic composition of sedimentary organic matter from two African rift valley lakes: Lake Edward, Uganda, and Lake Bogoria, Kenya. Material for analysis will come from surface grab samples and sediment cores. The work outlined in this proposal will be integrated with two larger studies of the Edward and Bogoria basins, the former under the auspices of the IDEAL project, the latter in a multidisciplinary study of sedimentation and tectonics in the Bogoria-Baringo segment of the eastern rift. The principal aims of the project are: (i)improved understanding of the primary controls on the isotopic composition of lacustrine o.m., (ii) the production of high resolution palaeoenvironmental records for the studied lakes, (iii) the identification of possible anthropogenically induced changes to the waterbodies. It is anticipated that results from the proposed research will provide specific information upon the influence of different carbon metabolic pathways and nitrogen cycling on the isotopic composition of phytoplankton organic matter, exceptionally high resolution records of change in the Edward and Bogoria waterbodies over at least the last 20 ka, and provide a historical perspective on the influence of land-use practices and other anthropogenic effects upon sedimentation in these lakes. Training content (objective, benefit and expected impact) In my Ph.D. study, I used stable isotopic analyses of inorganic and biogenic carbonates to reconstruct the post-glacial history of a variety of Swiss lakes. This work led to some important new insights into the Late Glacial and Holocene enviromnental history of western Switzerland. I wish now to extend my expertise in the application of stable i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'An expected multi-causal nature of spontaneous animal and human nephropathy in Bulgaria and South Africa' (2002-2006) targeting Sixth Framework.

assistant: **Abstract**

The proposal has addressed porcine/chicken nephropathies in Bulgaria which are morphologically different in detail and much more prevalent than those seen in Denmark, where their first classical description was made. The same nephropathies can only partly be attributed to ochratoxin A (OTA) as their incidence in Bulgaria is higher, possibly by one to two orders of magnitude, than it was in Danish pigs in the 1960s and 70s, but the average concentrations of OTA in Bulgarian feeds for pigs/chickens (100-200 p pb) were substantially lower than the 1-2 ppm required to reproduce the classical Danish porcine/chicken nephropathy of a similar severity. It seems, therefore, that Bulgarian nephropathy may have a multitoxic aetiology because it cannot be explained by th e concentration of OTA alone. Hence a possible synergistic effect between OTA and other mycotoxins is anticipated.This assumption is supported by our recent experiments, which revealed the strong synergistic effect between OTA and penicillic acid (PA), my cotoxins produced by the same fungi. The situation requires study to explain the aetiology of natural renal disease in Bulgaria and to compare with another similar nephropathy as in South Africa, which has not been studied in depth. This comparison will be made by means of toxicological and pathomorphological investigations of some tissue/serum samples taken at slaughter time from animals with marbled appearance of kidneys (Bulgaria) and biopsy material from humans (South Africa), where the mycotoxin fumoni sin B1 is thought to play a role, both originating from affected areas with known prevalence of porcine/human nephropathy.Training activities and transfer of knowledge in the field of mycotoxicological analysis (mainly for OTA, PA, citrinin, Fusarium toxi ns, e
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Toopi Regen: Unleash the power of urine to finally scale a real closed loop and regenerative farming system' (Toopi-Regen).

assistant: **Concept**

How can we revolutionize our food system while preserving a vital resource?18 million tons of mineral fertilizers are used every year in the EU. This massive use threatens our food security, health and environment, but remains essential for feeding humankind. Farmers have no viable alternatives. At the same time, human urine - rich in essential nutrients, N, P, K - is not only considered as a waste, but keep threatening our water sources when flushed in drinking water (6,000B L per year in the EU).At Toopi Organics, we aim to implement a sustainable and profitable agricultural model based on up-cycling human urine. Our unique and patented fermentation process produces microbial biostimulants using urine as a growth medium for microorganisms of agricultural interest as alternative to crop fertilization. Our urine-based products are approved across Europe, safe, easy-to-use, effective (proven in many field trials) and economically viable. They are fully adapted to scale regenerative agriculture by enhancing nutrients use efficiency, increasing soil microbiome biodiversity and avoiding the huge fertilisers greenhouse gas emissions. Our closed-loop solution is implemented at a local scale and is highly replicable: urine collection (in urban areas) and urine transformation in fermentation facilities are localized close to farmers needs.With the EIC support, we will deploy our model in Europe and promote a significant paradigm shift in the fertilisation market. The global biostimulants market is worth 3.4B (CAGR of 11%). It remains a niche market - with products dedicated mainly to value added crops and not really affordable for field crop growers. Our ambition is to become a leader of the biostimulant market category dedicated to substitute a significant proportion of minera
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Green Advanced Space Propulsion' (GRASP) under Seventh Framework.

assistant: **Objectives**

Space activities and applications play an important role in strengthening the competitiveness of Europe by scientific progress in the knowledge-based society, and by providing strategic influence and security. Major successful space missions under European leadership have placed ESA and its Member States, the European science community at the forefront. To continue this path Europe must have independent and competitive access to space. With the ITAR (International Traffic in Arms Regulations) continuing to impede the acquisition of US components, Europe thus needs to develop an assured independent source of propulsion components.  Today space craft propulsion relies heavily on toxic and carcinogenic hydrazines as propellants. Hydrazine itself is widely used as monopropellant and MMH and UDMH is used as bipropellant fuel. These propellants are a threat to people and the environment, and handling these toxic propellants impedes costly safety measurers.   As new ideas and new technologies emerged in the last years, and as the concerns about both the environment and the handling of carcinogenic propellants significantly increase, the so-called Green Propellants show potential improvements with respect to performance and cost. The goal of this project is thus to select the most promising green liquid propellant candidate/s and to push the propulsion technology to the level needed to prove that Green Propellant technology is feasible and competitive. Research and development on Green Propellants and adjacent propulsion technology in Europe is geographically fragmented and insufficiently funded. With the present consortium, some of the key-players in Europe will harmonize their capabilities to meet this demanding goal.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Development of a connexon-proteoliposome delivery system to ameliorate inflammatory and mechanical stress responses in the regeneration of osteoarthritic cartilage'.

assistant: **Innovation**

Regenerative medicine strategies using engineered scaffolds have shown promise to regenerate cartilage in degenerative conditions (e.g. osteoarthritis, OA). However, it is clear further cues are required to control repair in situ.  Small interfering (si)RNA can control protein expression but current cell delivery methods require endosome escape, limiting efficacy. Cell delivery of small molecules through connexons (Cx) bypasses the endosome and can be achieved by gap junction formation between cells and engineered Cx-containing proteoliposomes (Cx-PL). The most abundant connexin (Cx43) in cartilage cells (chondrocytes) is also a promising OA therapeutic target. It is highly upregulated in OA and is linked to inflammation, senescence, metabolic shifts and gene regulation. However, many questions remain on its mechanistic role in the disease. This project focuses on Cx43 as a therapeutic target and a delivery mechanism and aims to i) Investigate Cx43 roles in response to OA-associated proinflammatory and mechanical stimuli ii) Develop a Cx-PL delivery platform to knockdown Cx43 and restore healthy metabolism in OA. To study this I will assess chondrocyte responses to proinflammatory and mechanical signalling while controlling Cx43 expression and activity in culture. Using untargeted metabolomics, I will identify key responsive metabolic pathways and perform in vitro screens of the effects of supplementing these to promote healthy phenotypes. Finally, I will encapsulate Cx43-siRNA and a selected bioactive metabolite in Cx43-PLs, incorporate these into a collagen I-hyaluronic acid scaffold and test this delivery platform in vitro. This fellowship conducted with Prof. O’Brien at the Royal College of Surgeons in Ireland will enable me to build on my existing skills in two eme
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Marine chemical glycobiology: a molecular understanding of the carbon cycle and bioactive sulfated marine glycans' to be submitted under Horizon 2020.

assistant: **Abstract**

Marine microalgae sequester as much CO2 into carbohydrates as terrestrial plants. However, the marine carbon cycle is currently not understood in molecular detail. MARINEGLYCAN seeks to explore the marine biosphere using an approach rooted in chemical biology & automated glycan assembly (AGA) by inventing new tools for deciphering biological information.I will generate an assortment of tools: glycan microarrays, fluorescently labelled polysaccharides (FLAPS), Förster resonance energy transfer (FRET) probes, & activity-based probes (ABP) working at the Max Planck Institute (MPI) of Colloids & Interfaces in collaboration with the MPI for Marine Microbiology to allow the systematic study of the flow of carbon–from the level of individual enzymes to interdependent communities. These tools will be used to discover the bioactive epitopes of sulfated marine glycans–known to have anti-viral, anti-cancer, & neuroprotective properties. A new continuous flow photocatalytic process to access fluorinated glycans will be developed in the context of the project.While gaining a broad range of scientific techniques including AGA & techniques used in marine glycobiology, I will gain & develop my transferable skills & expand my network. All allowing me to have a successful career in both business & academia. These skills will be obtained through workshops provided by the Max-Planck Academy, managing of PhD students & mentoring by Prof. Seeberger. The knowledge & skills I gain working on MARINEGLYCAN will provide me with the skill set to collaborate with Industry–while also carrying out basic scientific research.MARINEGLYCAN seeks to gain a better understanding of the flow of carbon in the marine environment, allowing Europe to advance towards a green circular economy. With the potential t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Revolutionary trustworthy platform for seamless authentication of Internet users' (2014-2020), addressing dissemination and exploitation.

assistant: **Impact**

The trust model on the Internet is broken. Security-wise, today’s password-based authentication system is dead - more than 90% of current passwords are vulnerable to hacking. What’s worse, the user experience today is a really bumpy ride – registrations, logins, CAPTCHAs, and verification emails present significant obstacles for both the users and the service providers, and contribute to very low conversion rates. We at EXC Sp. z.o.o. (https://getexcalibur.com), a team of young enthusiasts are developing a revolutionary platform for secure and seamless authentication of Internet users – Excalibur Cloud Password Manager powered by our proprietary distributed cryptographic scheme. Excalibur utilizes mobile phones or a wearable computer – user’s most personal device – to act as a universal security token for the digital world. Using our unique scheme we create a strongly authenticated state on the phone and project it to any device you want to use so that you don't have to authenticate on that device again. Such as your PC, mobile device, or any other Internet connected device. All that while providing a seamless user experience – making authentication invisible for the user. Although our solution reached the private Beta version stage, our development is not yet completed – we continue its evolution focusing on enhancing its core components such as proximity detection, behaviometrics and browser sandboxing. Excalibur 2.0 is of strategic importance to our company as it helps harden and enhance our existing platform as well as to establish technological leadership. In order to do so, we are applying for SME Instrument Phase 1 funds to: (i) elaborate an exhaustive technical feasibility study focused on scale-up beyond our current Beta version of the platform; (ii) elaborate
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'European Telework Development'.

assistant: **Concept**

ETD's objective is to build Europe's confidence and competence in key aspects of the Information Society:TeleworkTeletradeTelecooperationby providing information on the potential benefits and stimulation of consensus development, so that citizens, enterprises and institutions benefit from today's technology and are better prepared to take advantage of emerging technologies.Understanding and effective use of technologies is essential to effective participation and prosperityA Telework Shop Window"During 1997 ETD seeks to further increase the value and use of the website by those who need to reach and engage with the market:suppliers and buyersexemplars and innovatorstelework associations and other user groupsemployers and unionspolicy makers and citizensand to further strengthen the network with partner sites in all European languages and in key international markets.Getting Europe ConnectedMany individuals who are ready to participate in the Information Society encounter barriers and difficulties. During 1997 ETD seeks to partner with other projects and enterprises to make the first steps easier and more productive for new users.Teletrade EffectivenessUsers complain that many European enterprises (and projects!) waste time and resources on websites that are unattractive or even unusable for the audiences they want to attract. Companies investing in websites too often fail to appreciate and respond to the inherently interactive nature of communications and relationship-building on-line, so that their website becomes a costly overhead instead of a revenue generator. During 1997 ETD seeks to codify this feedback into assessment mechanisms and cost effectiveness guidelines that will improve return on investment in websites, on-line marketing and on-line customer services.Br