RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Systematic mapping of the complexity landscape of hard algorithmic graph problems' (SYSTEMATICGRAPH) under Horizon 2020.

assistant: **Objectives**

Graph-theoretical models are natural tools for the description of road networks, circuits, communication networks, and abstract relations between objects, hence algorithmic graph problems appear in a wide range of computer science applications. As most of these problems are computationally hard in their full generality, research in graph algorithms, approximability, and parameterized complexity usually aims at identifying restricted variants and special cases, which are at the same time sufficiently general to be of practical relevance and sufficiently restricted to admit efficient algorithmic solutions. The goal of the project is to put the search for tractable algorithmic graph problems into a systematic and methodological framework: instead of focusing on specific sporadic problems, we intend to obtain a unified algorithmic understanding by mapping the entire complexity landscape of a particular problem domain.Completely classifying the complexity of each and every algorithmic problem appearing in a given formal framework would necessarily reveal every possible algorithmic insight relevant to the formal setting, with the potential of discovering novel algorithmic techniques of practical interest. This approach has been enormously successful in the complexity classifications of Constraint Satisfaction Problems (CSPs), but comparatively very little work has been done in the context of graphs. The systematic investigation of hard algorithmic graph problems deserves the same level of attention as the dichotomy program of CSPs, and graph problems have similarly rich complexity landscapes and unification results waiting to be discovered. The project will demonstrate that such a complete classification is feasible for a wide range of graph problems coming from areas such as
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Wood shield-an environmentally friendly non-toxic preservation methodology for fast grown stika spruce' demonstrating excellence, impact and implementation quality for a Fourth Framework call.

assistant: **Abstract**

The utilisation of renewable resource materials in the construction, animal husbandry and food packaging sectors is of increasing importance, particularly in Ireland where the current non renewable resources currently utilised are either non existing or in very short supply Sitka Spruce is an increasing natural, renewable resource which has significant application potential within the construction industry (beams, timber houses, etc.) animal husbandry (gates, fences) and food packaging (meat, vegetables & fruit etc.) if structural strength and resistance to humidity induced deterioration can be increased in a non-toxic and environmentally friendly method. A new methodology for seasoning the timber, which includes heat treatment and the application of super heated gas technology has been initially researched at the Institute for Environmental Technology (YTI) in Mikkeli Finland. If this methodology can be refined and proven in the instance of Sitka Spruce, it provides an opportunity to utilise the timber in glue laminated configurations for the construction, joinery and furniture sectors. It also has applications in fencing for animal husbandry and food packaging where currently it cannot be used currently as it is treated with CCA (Copper Chrome Arsenic), a highly toxic compound which renders it unusable. It further has the advantage that by substituting a non-toxic product, it eliminates the need for CCA dipping plants which, in themselves are highly dangerous and environmentally unfriendly
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Interconnection of the high speed rail network with other transport modes: Connection in metropolitan areas of HSR terminals' (HSR-COMET) under Fourth Framework.

assistant: **Objectives**

1- Carry out a comprehensive analysis of High Speed Rail (HSR) demand, identifying and describing HSR users, relevant/specific demand features and users' demand for urban intermodal connections.2- Determine which urban transport modes/options best meet users' requirements for interconnection with HSR terminals.3- Define priorities for the development of these interconnection options, based on an impact assessment analysis (social, economic and environment).4- Define general policy guidelines for developping and supporting the prioritary interconnection options, addressing economic, land use, financing, tariffs, interconnection services and legal/institutional issues. %5- Identification of 'demand segments' within the whole body of HSR users and individuation of corresponding transport demand features.6- Development of a cost-benefit multicriteria analysis model, calibrated in Rome, Paris and Frankfurt.7- Recommendations for the cities of Rome, Paris and Frankfurt.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Molecular Mechanisms of Natural Killer cell Cytotoxicity' (MOLMECHSNKTOX), addressing dissemination and exploitation.

assistant: **Impact**

The study of immunodeficiency syndromes such as familial hemophagocytic lymphohistiocytosis (FHL) and Griscelli Syndrome type 2 (GS2) has revealed a crucial role for Munc13-4, Stx11, Munc18-2 and Rab27a – members of protein families that regulate vesicle trafficking and membrane fusion – in cytotoxic granule exocytosis. Loss-of-function mutations in these proteins result in loss of target cell killing by NK cells and CD8+ T cells, resulting in a life-threatening sepsis-like condition. The precise molecular role of these proteins in granule release remains, however, incompletely understood.The objective of this project is to elucidate presynaptic signaling cascades leading to NK cell exocytosis, and thus obtain a detailed map of the sub-cellular events leading to granule release. The project is divided into three specific aims. Post-translational modifications of the known regulators of exocytosis will be studied. In a second line of investigation, other, as yet unknown, proteins that might be involved in this process, like priming factors, and scaffold and adaptor proteins will be explored. This work will be facilitated by insights from the fields of neuroscience and hormone release; the mechanisms of which also share an exocytic pathway, and for which molecules important for this process have already been discovered. Additionally, to obtain a complete picture of the signaling pathways involved, spatiotemporal patterns of second messenger dynamics during granule release will be assessed. Importantly, primary, human NK cells will be employed throughout this study.In conclusion, this project aims to increase the understanding of the complex molecular mechanisms involved in NK cell cytotoxicity, thus broadening the spectrum of immunodeficiency syndromes and improving the c
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'A networked training initiative for embedded systems design', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

The objective of the project is to address the shortage of highly skilled personnel in designing and manufacturing embedded systems. The consortium is composed by four European technical universities (Politecnico of Milan; Alari Institute in Lugano; EPF Lausanne; Universitat Politecnica de Catalunya) and by a group of microelectronics and related companies (ST Microelectronics, Mentor Italia and TXT in Italy; INTEL in Ireland; IMEC in Belgium; INTRACOM in Greece; Infineon in Germany). The project provides for a number of training initiatives, built around the Master course in embedded systems held at Alari.They are: grants for students from candidate countries; support to joint master projects with industry ; dissemination of course contents through summer schools and in-house courses at industry's premises; set-up of a mobility scheme for students (ECTS) and of a support infrastructure for remote learning and tutoring.OBJECTIVESThe main objective of the project is to address the shortage of highly skilled personnel for the European industrial segment involved in design or manufacturing of embedded systems. More precisely ANTITESYS aims:1) at preparing researchers/designers oriented to industrial needs, endowed with a cross-disciplinary education as well as with basic soft skills:2) at providing reskilling for employed personnel in companies, supporting life-long learning and;3) at creating a strong collaboration between Academia and Industry not only in research, but also in designing and organising a training initiative. At the organisational level, ANTITESYS aims at establishing a training network in microelectronics which allows for high flexibility of training and for mobility of trainees between training institutions and between industry and academia.DESCRIPTION O
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Highly Competent and Safe Titanium(IV) Therapeutic Frameworks that are Cancer Targeted based on Complex 1, 2, and 3D Chemical Architectures' (IV) under Horizon 2020.

assistant: **Objectives**

This proposal aims to develop custom designed anticancer therapeutic frameworks that are effective, stable, safe, and tumor targeted, based on the biocompatible TiIV metal. The Tshuva group has established that water stable phenolato TiIV complexes are especially effective as anticancer agents both in vitro and in vivo, with markedly reduced side effects. Optimal derivatives will be developed to combine activity, stability, and biological accessibility, by maintaining small steric bulk while incorporating strong binding donors and hydrophilicity. The mechanism of action will be investigated by chemical and biological methods, including analyzing bio-distribution, cellular pathways and targets, and interaction with bio-molecules. Specifically, the active metal centers will be linked to bioactive moieties through redox-sensitive S–S bonds to enable tumor targeting. Cell penetrating peptides will facilitate cellular penetration for redox-dependent release of the active species selectively in cancer cells; steroid moieties will direct selectivity to hormone-dependent cancer cell types. Since the combination of TiIV- with Pt-based drugs has shown synergistic effects, multi-active entities will include two or more metal centers, possibly also linked to a transport unit. In addition to linear conjugates, polymeric and dendritic assemblies, exploiting the enhanced permeability of cancer cells, will be constructed with theoretically unlimited options for targeted delivery of multiple active sites. Most importantly, flexible well-defined redox-sensitive cages, as well as rigid pH sensitive complex cages, constructed with customized 3D geometries, will enable specific targeting of any active compound or conjugate and selective dissociation only where desired. This study should yie
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'The Role of Arl Proteins in Retinal and other Ciliary Diseases' to be submitted under Seventh Framework.

assistant: **Abstract**

Arl (Arf-like) proteins, GTP-binding proteins of the Ras superfamily, are molecular switches that cycle between a GDP-bound inactive and GTP-bound active state. There are 16 members of the Arl subfamily in the human genome whose basic mechanistic function is unknown. The interactome of Arl2/3 includes proteins involved in retinopathies and other ciliary diseases such as Leber¿s Congenital Amaurosis (LCA) and kidney diseases such as nephronophthisis. Arl6 has been found mutated in Bardet Biedl Syndrome, another pleiotropic ciliary disease. In the proposed interdisciplinary project I want to explore the function of the protein network of Arl2/3 and Arl6 by a combination of biochemical, biophysical and structural methods and use the knowledge obtained to probe their function in live cells. As with other subfamily proteins of the Ras superfamily which have been found to mediate similar biological functions I want to derive a basic understanding of the function of Arl proteins and how it relates to the development and function of the ciliary organelle and how they contribute to ciliary diseases. The molecules in the focus of the project are: the GTP-binding proteins Arl2, 3, 6; RP2, an Arl3GAP mutated in Retinitis pigmentosa; Regulators of Arl2 and 3; PDE¿ and HRG4, effectors of Arl2/3, which bind lipidated proteins; RPGR, mutated in Retinitis pigmentosa, an interactor of PDE¿; RPGRIP and RPGRIPL, interactors of RPGR mutated in LCA and other ciliopathies; Nephrocystin, mutated in nephronophthisis, an interactor of RPGRIP and Arl6, mutated in Bardet Biedl Syndrome, and the BBS complex. The working hypothesis is that Arl protein network(s) mediate ciliary transport processes and that the GTP switch cycle of Arl proteins is an important element of regulation of these processes.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Ecmtb2002' in the context of a Fifth Framework call.

assistant: **Objectives**

Mathematical and theoretical biology and medicine is a diverse field in which interdisciplinary collaboration is essential for progress. The field ranges from experimental research linked to mathematical modelling to the development of more abstract mathematical frameworks in which observations about the real world can be interpreted and with which new hypotheses for testing can be generated. The medical, industrial and social interests in the development of this research field are undisputable. Insights and predictions from mathematical modelling are used increasingly in decision support in medicine (e.g. immunology and spread of infectious diseases, cancer research, cardio-vascular research, neurological research, optimisation of medical treatments, imaging), and environmental nature management, climate problems, agriculture and management of natural resources.Fast developments in areas such as biotechnology (e.g. genome projects, genetic modification) continue to add new focal points of activity to the field. The European Conference on Modelling and Computing in Biology and Medicine has as its goal to foster interdisciplinary collaboration between mathematicians and bio-scientists and to act as the main forum for the exchange of recent research results and new research directions to the widest possible community in theoretical biology and medicine.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Trials on Distributed speech recognition for mobile network embedded voice-controlled services' in the context of a Fifth Framework call.

assistant: **Objectives**

Voice-driven services over the telephone networks in Europe are continuously increasing. Today, in such traditional voice-driven servers, the recogniser is embedded in the telecommunication network and test results show that mobile network low bit rate coding and transmission errors degrade the performance of speech recognition severely. As a solution, the Distributed Speech Recognition architecture (DSR) has been designed by the ETSI-AURORA Group in order to improve robustness of voice-driven servers against these networks effects. Indeed such Services for customers are currently emerging in mobile networks, and, two Operator Partners, Sonofon and Bouygues Telecom, are highly interested in a real context DSR validation, which is the major goal of TriaDis. Three other Partners - BOSCH for the Terminal, L&H and CPK for DSR - are offering their background to implement the DSR terminal-server platform for these Trials.Objectives:The main goal of TriaDis is to validate, through Trials with selected group of end-users, the DSR" improvement in terms of performance and usability on Voice-controlled server embedded in a real Mobile Network (GSM, DCS-1800). DSR concept has been recently introduced, designed and evaluated by the ETSI-AURORA Group with the target to make a standard. Hence TriaDis plans to implement "DSR" on a real server application accessed by any mobile terminal and perform validation trials. Indeed no real-context trials have been done but only tests on simulated environments in the frame of ETSI-AURORA. Moreover, the Consortium possess an important background allowing to get ready in a very short-term a validation platform after adaptation from an existing Terminal prototype platform and speech-controlled dialogue application (L&H, CPK). If successful, high ex
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'ORGANIC FARMING INNOVATIONS NETWORK EUROPE'.

assistant: **Concept**

Oh-FINE´s is a 48-month long project that aim to empower European farmers and smallholders through the definition, enhancement and transfer of competitive and efficient organic farming knowledge and alternatives that address farmer’s capacities, consumer needs and evolving food market changes. To this end Oh-FINE will create pan-European Organic Farming Learning Community (OFC) structured in four main technological pillars: 1) to develop a multidimensional framework on the organic farming knowledge and practices; 2) to establish a multi-agent approach organic farming learning system and validate the  framework in 5 case of studies areas across Europe, 3) to collect distribute and disseminate to farmers and other stakeholders of easily accessible practice-oriented knowledge focusing on organic farming and covering cereals, oilseeds, protein crops, and livestock, and 4) to develop a Decision Support System ICT Tool for farmers.


**Keywords:** Farming Learning Community, conversion; knowledge exchange; thematic network; multi-actor; innovation; AKIS; cooperation; co-creation; cross-fertilisation; dissemination/spreading of organic farming; empowering farmers.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Application Aware, Life-Cycle Oriented  Model-Hardware Co-Design Framework for Sustainable, Energy Efficient ML  Systems' (SustainML) under Horizon Europe.

assistant: **Objectives**

AI is increasingly becoming a significant factor in the CO2 footprint of the European economy.  To avoid a conflict between sustainability and economic competitiveness and to allow the European economy to leverage AI for its leadership in a climate friendly way, new technologies to reduce the energy requirements of all parts of AI system are needed. A key problem is the fact that tools (e.g. PyTorch) and methods that currently drive the rapid spread and democratization of AI prioritize performance and functionality while paying little attention to the CO2 footprint. As a consequence, we see rapid growth in AI applications, but not much so in AI applications that are optimized for low power and sustainability. To change that we aim to develop an interactive design framework and associated models, methods and tools that will foster energy efficiency throughout the whole life-cycle of ML applications: from the design and exploration phase that includes exploratory iterations of training, testing and optimizing different system versions through the final training of the production systems (which often involves huge amounts of data, computation and epochs) and (where appropriate) continuous online re-training during deployment for the inference process. The framework will optimize the ML solutions based on the application tasks, across levels from hardware to model architecture. AI developers from all experience levels will be able to make use of the framework through its emphasis on human-centric interactive transparent design and functional knowledge cores, instead of the common blackbox and fully automated optimization approaches in AutoML.  The framework will be made available on the AI4EU platform and disseminated through close collaboration with initiatives such as the