RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Enhancing the Performance of Cellulose based Insole Boards' will create measurable scientific, societal and economic impact aligned with Fourth Framework.

assistant: **Impact**

Development of improved characterisation and service prediction techniquesOver 40 test methods for cellulose insole boards, addressing 26 properties, have been reviewed. Key needs identified were procedures for measuring lateral water transmission, improved reliability of tests for biodeterioration resistance and improved procedures for determining binder content. A wicking test using a material strip has proved able to distinguish between materials, but a new procedure in which water is introduced to one surface and wicks from a circular zone more closely simulates wetting in wear. A moisture transfer test that has the advantage of wetting only from one surface has also been developed. The soil burial test for biodeterioration has been speeded up by using a standard compost of controlled moisture content, and a means of exposing materials on one side, as in the shoe, has been developed and found to correlate with service performance. A technique for binder content based on acid digestion of cellulose has been speeded up by increasing the temperature, and validated using raw materials and blends.Identification of the key factors for improved resistance to microbial deterioration and enhanced comfortA range of boards for various footwear applications, including examples with and without biocide, has been tested before and after soil burial. The results showed a marked variation in properties, and some boards were seriously weakened by soil burial with flexing and scuff resistance especially sensitive to change. Biocides were found to be beneficial. Electron microscopy and tensile tests have shown fibre-binder interactions to be important. Ageing tests have ruled out cellulose hydrolysis as a deterioration mechanism. The acid digestion technique for binder content has bee
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Enhancing cognitive flexibility in autism' (ENHANCINGFLEXIBILITY) targeting Seventh Framework.

assistant: **Abstract**

The proposed project seeks to apply theoretical knowledge and insights from the research field on cognitive training and develop interventions that target flexible behaviour in autism. While empirical evidence for success of cognitive training is provided by improvement of skills within a certain task context, this project aims to determine which training regimens would target underlying mechanisms and enable the transfer of trained skills to other tasks, as well as to everyday behaviour. The proposed project builds upon my previous research on autism as well as the novel methodological approach I used by including game-like elements in my experiments. Neuroimaging techniques in the proposed project will complement my existing skills with new imaging methods (EEG). They will also provide further insight into the brain regions and attentional processes involved in cognitive flexibility, illustrating a multidisciplinary character of the proposal. Acquiring my own distinctive research niche will significantly enhance my prospects of gaining professional employment. Combined with my professional experience, this new theoretical and applied knowledge will provide me with a diverse skill set and make me an attractive candidate for future academic positions.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'IL-7/IL-7R signaling networks in health and malignancy' (IL7sigNETure), addressing dissemination and exploitation.

assistant: **Impact**

Deregulation of signal transduction is a feature of tumor cells and signaling therapies are gaining importance in the growing arsenal against cancer. However, their full potential can only be achieved once we overcome the limited knowledge on how signaling networks are wired in cancer cells. Interleukin 7 (IL7) and its receptor (IL7R) are essential for normal T-cell development and function. However, they can also promote autoimmunity, chronic inflammation and cancer. We showed that patients with T-cell acute lymphoblastic leukemia (T-ALL), an aggressive hematological cancer, can display IL7R gain-of-function mutations leading to downstream signaling activation and cell transformation. Despite the biological relevance of IL7 and IL7R, the characterization of their signaling effectors remains limited. Here, we propose to move from the single molecule/pathway-centered analysis that has characterized the research on IL7/IL7R signaling, into a ‘holistic’ view of the IL7/IL7R signaling landscape. To do so, we will employ a multidisciplinary strategy, in which data from complementary high throughput analyses, informing on different levels of regulation of the IL7/IL7R signaling network, will be integrated via a systems biology approach, and complemented by cell and molecular biology experimentation and state-of-the-art in vivo models. The knowledge we will generate should have a profound impact on the understanding of the fundamental mechanisms by which IL7/IL7R signaling promotes leukemia and reveal novel targets for fine-tuned therapeutic intervention in T-ALL. Moreover, the scope of insights gained should extend beyond leukemia. Our in-depth, systems-level characterization of IL7/IL7R signaling will constitute a platform with extraordinary potential to illuminate the molec
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Widening gene pool of bread wheat by hybridization with Aegilops biuncialis supported by advanced genetic and chromosome genomic approaches', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

The widening of gene pool of bread wheat (Triticum aestivum) by employing its wild relatives as donors of new alleles and genes will ensure the ability of wheat to sustain yield quality and quantity under adverse environmental conditions. Species from genus Aegilops represent a rich source of agronomically important traits, such as leaf rust resistance, grain nutritional quality and abiotic stress tolerance. To date, the utilization of wild genetic diversity has been hampered by low throughput of methods used to select introgression lines and the lack of knowledge on the genomes of wild relatives. The multidisciplinary AEGILWHEAT project integrates the applicant’s expertise in interspecific hybridization and cytomolecular genome analysis of Aegilops species with the state of art expertise in flow-cytometric sorting and genomic analysis of plant mitotic chromosomes in the Centre of Plant structural and Functional genomics (IEB, Olomouc, CZ). The aims of this project are to (1) isolate individual U and M chromosomes from Aegilops biuncialis and (2) identify their gene content and produce polymorphic markers (SNPs, INDELs) by next-generation sequencing and bioinformatic analyses. The genes and new markers will be integrated into (3) a new high resolution genetic linkage map of Ae. biuncialis. The marker-assisted selection system based on the ordered markers will be used for the (4) high throughput selection of wheat-Ae. biuncialis introgression lines. The training through the research will extend the expertise of the applicant by new skills in molecular genetics, genomics and bioinformatics so that he can apply innovative genomics approaches to speed up his wheat pre-breeding programmes in Hungary. The project will deliver valuable information to geneticists and breeders o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'REGIME: Transmission Regimes of Climate-Sensitive Infectious Diseases in Latin America' (REGIME).

assistant: **Concept**

Extreme climatic events, environmental degradation and socio-economic inequalities exacerbate the risk of mosquito-borne disease (MBD) epidemics and modulate the transmission regimes of these diseases. Most MBDs can coexist and share patterns, which are sensitive to biodiversity loss, land use and land cover change, as well as climate, and socioeconomic and demographic factors. Determining the spatial and temporal scales at which these complex factors interact and modulate disease transmission can help to target effective control and prevention strategies. This research goes beyond the state-of-the-art by developing an innovative modelling tool called REGIME to assess the relative impact of multiple determinants on MBD emergence, spread and co-circulation in Latin America. Models will be formulated using data for Brazil over the past 20 years at the municipality level (5,570 municipalities). Multivariate cluster analysis will be performed to propose a transmission regime classification (e.g. endemic, epidemic, episodic) using disease case time series for each municipality each year to identify temporal changes in the transmission regimes. A model based on the transmission regimes will be designed to disentangle the role of different disease drivers, using multi-source data and random effects, which account for additional layers of uncertainty and help identify unknown spatial patterns, inter-annual signatures and similarities or differences between the drivers for each disease. The knowledge gained from Brazil will be applicable in a broader context in Latin America, by validating the model framework in the context of disease risk scenarios shared by those countries. REGIME will facilitate the generation of actionable knowledge to inform local risk mapping and build rob
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Auctions for Renewable Energy Support II' (2014-2020), addressing dissemination and exploitation.

assistant: **Impact**

Building on the insights of the recently finalized AURES project, AURES II investigates auction design options in more detail to determine their policy performance depending on different of policy objectives and give recommendations on their use. We apply a multi-methodological approach, including literature review, theoretical analysis, case studies, surveys, and empirical and quantitative methods such as econometric analysis and model simulations. The project expands the empirical base created in AURES in several directions. It continues the monitoring of ongoing and planned auction schemes. Case studies will now be complemented by a comprehensive online auction database, and quantitative analysis of how auction design features affect auction performance. The effects of auctions are further explored in two directions: (i) Developments in RES sector value chains and innovation processes in reaction to auctions, and (ii) Changes in financing patterns of RES projects in reaction to certain auction design specifications.  AURES II will inform currently ongoing auction-related policy debates: (i) Challenges of cross-border openings of auctions; (ii) the question of technology-neutrality, i.e. of combining two or more RES-E technologies in one auction; and (iii) future challenges, including the necessity for and requirements towards auctions due to changing electricity markets, generation patterns, and other framework conditions such as actor diversity.  The multi-methodological approach is accompanied by a strong involvement of relevant stakeholders including policy makers and industry representatives. The project builds upon and expands the strong network from AURES, allowing policy makers and industry to exchange expectations, experiences and ideas. This active dialogue
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'BIKE - Biofuels production at low - Iluc risK for European sustainable bioeconomy' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

The EU ILUC directive in 2015 introduced in the legislative framework a new concept for transport biofuels, the indirect land-use change (“ILUC”). Following, the recently issued red ii Directive introduces an exemption for biofuels, bioliquids and biomass fuels certified as low ILUC-risk toward the phasing out requirement for high-iluc risk feedstocks. The respective delegate act defines as low ILUC risk: ‘fuels produced in a way that mitigates ILUC emissions, either because they result from productivity increases or they come from crops grown on abandoned or severely degraded land’. The aim of the proposed project is to support the EC in the foreseen revisions of REDII by providing evidence, measuring and widely disseminating the market potential of low ILUC risk value chains for biomass, biofuels and bioliquids in Europe. The work will focus on three specific pathways to achieve low ILUC-risk, sustainable value-chains for advanced biofuel production, distinguished among the type of biomass, the cultivation and production mode. The project will map and evaluate both possible productivity increase for crops grown on abandoned or severely degraded land, and the feasibility of a new biogas-to-liquid production route. The core activity of BIKE project will be to investigate on the reliability of identified low-ILUC risk biofuels production routes, assessing the environmental, social and economic sustainability of proposed solutions.  A detailed assessment of existing policy and legal framework, influencing the deployment of low ILUC risk value chains will also be performed to inform future policy and decision making in this area.


**Keywords:** Sustainable value chains, Low-ILUC feedstock, Renewable Energy Directive
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Ultra-sensitive Field-resolved Infrared Spectroscopy for Early Disease Detection' (UFRISED).

assistant: **Innovation**

Early detection is one of the most effective ways to improve the survival rate for diseases like cancer. However, current diagnoses often rely on invasive procedures and specialized tests, posing challenges for regular monitoring.Field-resolved infrared spectroscopy, which probes the ""molecular fingerprint"" of human blood, has achieved remarkable detection sensitivity by combining ultrafast laser technology with electric-field infrared detection. Despite its potential, the technique has yet to meet the stringent requirements of early screening, including single nanogram per millilitre sensitivity, 10^12 dynamic range, and long-term stability.The proposed project — 'Ultra-sensitive field-resolved infrared spectroscopy for early disease detection' aims to overcome these challenges by developing a ground-breaking instrument for field-resolved infrared fingerprinting of human blood plasma samples and demonstrate its performance for health monitoring. In particular, the researcher intends to develop: (i) a multi-kHz delay scanning system based on two Cr:ZnS lasers, synchronized down to single-femtosecond timing precision which aims to record measurements faster than most laser noise contributions, (ii) super-octave-spanning field-resolved infrared detection with a dynamic range exceeding 10^12, and (iii) an ultra-rapid referencing scheme that simultaneously records reference infrared electric fields with the measurement to realize standardization of the infrared molecular fingerprints and the long-term reproducibility.By addressing these limitations, the project will achieve unprecedented levels of sensitivity, dynamic range and stability. It provides an avenue for analyzing serum and plasma samples across a wide range of individuals and time frames, potentially uncovering
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Relational Symmetry in the Baboon: towards symbols and language'.

assistant: **Objectives**

Language and the symbolic use of labels underpin human cognition.  As these features imply back and forths between label and labelled object, they require relational symmetry: the capacity to reverse a learned relation A->B into B->A. In non-human animals, such flexible encoding of bidirectional relations has been difficult to obtain experimentally, mostly due to their failure to reverse stimulus relations. This apparent absence of symmetry suggests an evolutionary gap at the origin of human language. Yet, a number of procedural biases, inlcuding perceptual ones, may account for this failure to demonstrate symmetry. Moreover, all studies have relied on specific motor outputs to reveal symmetry, whereas symmetric relations may simply not be learned in such an explicit form.  Using the baboon as model primate species, and a worldwide unique, automatized, high-throughput behavioral platform as experimental system, we will conduct new experiments to re-assess this question. We will implement relational learning procedures which correct for all biases identified in past experiments, and rely on implicit rather than explicit measurements to test for the emergence of symmetry. Furthermore, we will study the effects of symmetry on stimulus networks, to assess the baboons’ abilities for flexible relational encoding when more stimuli are involved. A crucial feature of natural intelligence such as relational symnetry ought to be also considered in Artificial Intelligence (AI) systems, as their relational learning abilities are still limited. We will thus investigate the capacity of existing connectionnist models (e.g. Recurrent Neural Networks) to learn symmetrical associations of stimuli, and will explore new architectures able to implement symmetry. Both symmetry or its absence
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Fault Activation and Earthquake Rupture' under Horizon 2020.

assistant: **Concept**

Earthquakes are one the most significant hazards for human society, and at the same time, they remain the most elusive. Advancing our ability to understand their occurrence and intensity is of paramount importance for efforts to make society more resilient to the risk posed by catastrophic earthquakes. Progress in further understanding of earthquake physics is hindered by the lack of appropriate experimental facilities for observing the earthquake process at close distance and further advances will depend on the possibility to perform controlled experiments of fault stimulation and earthquake initiation at relevant depths and pressures. A new deep underground experimental facility is being constructed in the Bedretto tunnel in the Swiss Alps, offering a unique opportunity to perform fault stimulation and earthquake nucleation experiments on a scale and depth not available until now. FEAR will conduct the first-ever program to: (i) perform controlled 50-100 m scale fault stimulation experiments in basement rock at over 1'000m depth, (ii) pre-condition the stress distribution on the fault to perform real-time tests of different physical source and forecasting hypotheses, (iii) deploy data-driven approaches and real-time modelling to conduct structured prospective forecasting experiments, (iv) integrate and validate results from deep-underground experiments, experimental rock-deformation laboratories, numerical physics and dynamic modeling, and observations from natural earthquakes. The ERC Synergy framework enables to bring together the key complementary competences in Europe and to integrate them into a coherent program.


**Keywords:** Earthquake nucleation, Fault stimulation, Underground Laboratory, Experimental Rock Deformation Laboratory, Earthquake source physics