RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Streamlining Clinical Applicability of Ultrasound Localization Microscopy via Advanced Reconstruction Models' under Horizon Europe.

assistant: **Concept**

The ULMARM, or Ultrasound Localization Microscopy with Advanced Reconstruction Models, seeks to improve ultrasound imaging by addressing key challenges in Ultrasound Localization Microscopy (ULM). Traditional ULM methods require long acquisition times and ultra high frame rates to track microbubbles (MBs) accurately, stretching the capabilities of current clinical ultrasound systems. ULMARM aims to solve these challenges by developing advanced reconstruction techniques and integrating deep learning (DL) models. The goal is to relax frame rate demands while maintaining high-quality super-resolved imaging and accurate motion tracking, making ULM more feasible for clinical applications. In ULMARM, I propose recasting ULM as a mathematical inverse problem to achieve super-resolution in both space and time jointly. By treating the relationship between MB movement and ultrasound frames as a generative forward model, I will infer the most probable MB trajectories from observations using a Bayesian posterior maximization approach. To tackle inherent challenges, I will utilize advanced deep generative models and strong data-driven priors to streamline the inference process. The ULMARM project is organized into six work packages (WPs). WP1 focuses on new sparse coding methods to relax frame rate while preserving image quality. WP2 develops mathematical models for direct reconstruction, including motion compensation for improved accuracy. WP3 uses DL to reconstruct missing data, improving both spatial and temporal resolution. WP4 extends these methods to 3D ULM, tackling challenges like high volume rates and out-of-plane motion. WP5 focuses on evaluating these techniques with experimental and clinical datasets. WP6 handles project management and training. The MSCA Fellowship will
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'INTEGRATION OF DEDICATED FOR ADVANCED TRAINING LINKED TO SMALL AND MEDIUM ENTERPRISES AND INSTITUTES OF HIGHER EDUCATION', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

IDEALS will develop a modular training system which will make flexible distance learning packages available on demand for small and medium-sized enterprises (SMEs) and universities. Telematics-based modular courses, co-authored for cost effectiveness, will be delivered across Europe via interconnected local training centres serving both groups. Courses for in-company training, to be tested initially by some 20 SMEs, will be adapted to their individual needs and real-life problems. Testing in universities will involve students in computer labs or at home, with possibilities for remote tutoring and group learning.The IDEALS project aims at installing and positioning flexible, on-demand, telematics based distance learning and training services in the market. A Modular Training System (IDEALS-MTS) will be developed and a European-wide network of Local Training Centres (LTCs) will be established. The Modular Training System will allow cost-effective co-authoring of courses and flexible, cost-effective learning for users. The IDEALS project will enhance the results of the DEDICATED project (3rd Framework Programme) and transform them into marketable products.In IDEALS, the Modular Training System will be enhanced to support multiple users at the same time. Courseware will be stored in a distributed database, can be enriched by using real-time simulations (microworlds). Support will be provided for course authoring, learning, and tutoring.The Local Training Centres are interconnected to provide a uniform courseware domain with European-wide access. Different forms of networking will be tested like modems, ISDN, Internet, and satellite links.IDEALS will be demonstrated and evaluated in pilots for Institutes of Higher Education and SMEs.In the Institutes of Higher Education Pilo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'European Leadership in Space Astrometry' (ELSA) under Sixth Framework.

assistant: **Objectives**

ELSA brings together world-leading expertise in space astrometry - the use of space platforms for mapping the three-dimensional structure of our Galaxy - with specialists on numerical algorithms and software engineering for the double purpose of (1) preparing for the scientific exploitation of data from the European Space Agency's astrometric mission Gaia, scheduled for launch in 2011, and (2) training the next generation of researchers in this uniquely European specialty to maintain and extend European leadership in space astrometry.Gaia will perform a stereoscopic census of our Galaxy by measuring accurate distances, motions and astrophysical data for a billion stars. The results will greatly affect nearly all areas of astrophysical research. The scientific management of the mission, including the complex data analysis, requires a mix of specialist skills in space astrometry, software engineering, numerical methods and instrument modelling. This combination is rarely found at a single institute and never in current PhD programmes. It exists however on the European level thanks to the ongoing preparation effort for Gaia and past experience from Hipparcos (launched by ESA, 1989).The RTN will enhance collaboration between key institutes in the field and transmit the expertise acquired to the next generation of researchers. The research programme has challenging but tangible goals whose outcome will be a key contribution to the Gaia preparations. The data analysis problem is penetrated through novel research, numerical simulations, and GRID computing, leading to new and improved methods for its solution.The appointment of ESRs and ERs is used to achieve a balanced mix of competence, e.g. between astronomy and software engineering, and to ensure a lively exchange of result
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'The SESAR Knowledge Transfer Network' (Engage), addressing dissemination and exploitation.

assistant: **Impact**

Engage is a KTN proposed for European air traffic management, building on the solid foundation of previous actions, and introducing novel features and actions. Previous attempts to involve industry in the earlier maturity phases of ATM research have only partly been successful. We recognise that additional actions and incentives are necessary. With a balanced consortium, permeating all features of our proposal is the pronounced and active engagement of industry partners. At the core of the network are thematic challenges, supported by dedicated workshops. Catalyst funding will support focused projects, thus stimulating the transfer of exploratory research results towards ATM application-oriented research. This approach is enabled by the budget released through our lean management and compact consortium team. The network will establish a knowledge hub, in which members across the research community are continuously involved. This will include an observatory and undertake the role of devising and maintaining the long-term roadmap development of innovative and interdisciplinary ATM concepts beyond SESAR 2020. The knowledge hub will be the one-stop, go-to source for information in Europe. Our vision of the network is that of an enduring partnership between academic, operational and industrial partners exchanging needs, ideas and information to ensure the relevance and applicability of research and uptake of new concepts and methods.


**Keywords:** Knowledge transfer network, air traffic management, SESAR 2020, thematic challenges, knowledge hub, repository, development roadmap
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Social Sciences and Humanities for Climate, Energy aNd Transport Research Excellence' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

The Social Sciences & Humanities for Climate, Energy aNd Transport Research Excellence (SSH CENTRE) project brings together 13 leading organisations from across the EU, including: 3 universities, 4 research institutions, 2 stakeholder network organisations, and 4 R&I and communications SMEs. Our partners bring world-leading expertise across SSH and STEM disciplines applied to climate, energy and mobility, covering neutrality, community-led initiatives, heating and cooling, circular economy and sufficiency, and digital technologies. Partners will reach 228,880+ stakeholders by leveraging their significant experience in transdisciplinarity and citizen engagement, and networks that span academia, policymakers at various levels, the private sector, civil society and citizens. Our objectives directly address the call challenge with an aim to support cross-sectoral collaborations and empowerment of citizens and networks towards the development of socially innovative solutions for the EU’s climate transition. Issues related to Open Science, inclusivity and diversity – especially with regards Southern and Eastern Europe and different career stages – are at the heart of the project. SSH CENTRE will meet its objectives through a set of 7 carefully-designed Work Packages. Key activities involve: development of novel SSH-STEM collaborations to facilitate the delivery of the EU Green Deal; SSH knowledge brokerage to support regions in transition; and the effective design of strategies for citizen engagement in EU R&I activities. Outputs include action-led agendas and building stakeholder synergies through regular Policy Insight events. The high-profile virtual SSH CENTRE, and its 660+ members, will thus represent a ‘go-to' gateway for Cluster 5 SSH research excellence, delivering in
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on '“Yeast” genetics in mammalian cells to identify fundamental mechanisms of physiology and pathophysiology'.

assistant: **Concept**

Some organisms such as yeast or social insects are haploid, i.e. they carry a single set of chromosomes. Organisms with a single copy of their genome provide a basis for genetic analyses where any recessive mutation of essential genes will show a clear phenotype due to the absence of a second gene copy. Recessive genetic screens have markedly contributed to our understanding of normal development, basic physiology, and disease. However, all somatic mammalian cells carry two copies of chromosomes (diploidy) that obscure mutational screens. Although deemed impossible, we were able to develop generate mammalian haploid embryonic stem cells, thereby breaking a paradigm of biology.Our novel stem opens the possibility of combining the power of a haploid genome with pluripotency of embryonic stem cells to uncover fundamental biological processes in defined cell types at a genomic scale. The following projects are proposed:1. Towards“yeast” genetics in mammalian stem cells. Development of optimized technologies for rapid, genome-wide screens via repairable mutagenesis. Mutational bar-coding to introduce quantitative genomics to mammalian biology.2. Forward genetic screens to uncover essential stem cell genes, identify novel stemness factors, develop improved systems for iPS cell derivation, and to perform synthetic lethal screens for anti-cancer drugs.3. Reverse genetics using to identify and validate genes involved in cardiovascular physiology, brown and white fat cell development, and pain sensing.4. Hit validation – exemplified by resistance to the bioweapon ricin.Haploid embryonic stem cells carry the promise to revolutionize functional genetics and allow rapid, near whole genome-wide mutational forward genetics analysis and reverse genetics in defined cell types. Our syste
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Basin scale measurements of microplankton p/r balances in the euphotic zone - relationship wirh midwater respiration' (1994-1998), addressing dissemination and exploitation.

assistant: **Impact**

Research objectives and content 1.- To provide a better understanding of the range, variability and environmental control of net microplankton community production in the euphotic zone of the ocean. This variable (defined as the difference of gross primary production minus total community respiration) corresponds to the potentially exportable production of organic C to ocean depths. In order to fulfil this aim, the large-scale latitudinal (AMT-6 cruise from Cape Town to UK) distribution of community production will be determined in the euphotic zone alongside hydrographic features and microplankton community structure. Estimates of P/R balances are very scarce, especially in oligotrophic regions. Hence, specific attention will be given to this areas where, moreover, recycling of C within the euphotic zone is assumed to play an especial: important role in ecosystem dynamics and C budget. A process oriented cruise to the oligotrophic Atlantic will be done the year 2. 2.- To study the relationship between euphotic zone P/R balance and midwater remineralisation. Alongside euphotic zone net community production measurements, euphotic zone respiration and midwater remineralisation measurements will be made by means of a novel and sensitive method of measuring respiration. This will enable estimates of the balance between production and consumption of organic matter to be extended to greater depths than currently routinely measured. The large range of hydrodynamic/trophic conditions which are intended to be covered may provide insight into the range that balance and the environmental forcing over that relationship. Training content (objective, benefit and expected impact) The cooperation in the validation of the CTC technique for measuring deep respiration is an excellent oppo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Small carrier peptides as a new tool for selective drug delivery (PEPTIDES IN DRUG DELIVERY)' in the context of a Fifth Framework call.

assistant: **Objectives**

The goal of the proposed project is the development of novel types of membrane translocation peptides acting as shuttles for a controlled cellular delivery of ant microbial and antiviral drugs, which otherwise do not cross the membrane barrier. Starting point of this proposal are carrier peptides. The outlined experiments shall establish a basic knowledge of the essential requirements for the internalisation of such compounds and lead to model systems in which are effects of systematic variations of known carrier peptide sequences on translocation of drug cargoes across the cell membrane and their biological effects can be explored. In a second step, we will apply our results to develop a new rationale for the selective delivery of ant microbial and antiviral cargoes. Because of they're hydrophobic and polarity the intra- and Tran cellular transport of such therapeutics is particularly challenging. In a third approach, novel antiviral drugs will be developed and new therapeutic concepts will be established. The evaluation of these concepts implicates the application of the translocation carriers.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'ONCOlogic patient profiling and personalized treatment through SMART bedside diagnostics' (ONCOSMART).

assistant: **Concept**

ONCOSMART is the first In-Vitro Diagnostic (IVD) system that determines the effectiveness of anticancer drugs for a specific patient, testing live cell response to one or multiple cancer drugs. ONCOSMART analyses bone marrow or blood samples from a specific cancer patient, providing the results within 24-48 hours. This “functional profiling” approach has shown superior performance in non-automated systems to current molecular/genomic methods in predicting individual patient’s response to anticancer treatments.ONCOSMART is a fully-automated and standardised functional profiling platform that is made available to doctors and researchers to identify the most suitable cancer therapy for individual patients and also aid patient selection in clinical trials. The innovative platform analyses the interactions between anticancer drugs and live tumor cells contained in 2 mL of blood or bone marrow samples. Cellply has freedom to operate and protected ONCOSMART with 2 patent families issued in EU, US and China, 1 issued in EU, 1 pending PCT application, 2 pending Italian applications. Additional value is captured by 4 patent applications to be submitted in 2018-2019. ONCOSMART can test anticancer drugs including targeted, chemo and immunotherapies alone or in combination. The test results guide the selection of: 1) the appropriate therapy for a specific patient; 2) cancer patients for specific clinical studies; 3) cancer patients for novel therapies in clinical development. The platform has been fully-engineered and tested on leukemia patients (AML), proving its predictive power, and is extended to other hematologic and solid tumors in future developments. Within this project, CellPly has the goal to industrialise the platform, validate its analytical and clinical performance and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Printable functionalities for truly autonomous, intelligent lighting and signalling systems'.

assistant: **Objectives**

PRIAM addresses the development of two new product families:Light emitting autonomous road signsAutonomous car signals and taillightsThe underling technology consists on the integration on a plastic foil of:A solar cellA thin film batterySolid state light sourcesA sensor of ambient lightA Radio Frequency RF communication elementAn energy management processing unit.The developed systems do not need to be connected to an external source of energy, there is no need of expensive cabling or dedicated infrastructures.The new road signs can be easily applied on existing road panels which will then be luminous assuring high visibility in all climate conditions. The average age of car drivers is continuously increasing with associated lower reaction times and lower visual acuity. Benefits are then straightforward in terms of road safety in that a relevant share of car accidents happens at night because of drivers' hesitations due to low visibility of road signs. While the car is approaching the road sign, the RF element communicates with the central processor of the car which can inform the driver by either presenting the information on the display or by a voice synthesizer.The new car signals and taillights are very thin and light; they can be easily integrated into the car body and do not need to be connected to the main battery system. The RF element assures the communication with the central computer and the pedal. The system represents a considerable advantage for conventional cars in terms of the overall lower systems complexity and reduction of fuel consume. However the major advantage is foreseen for the development of efficient electrical vehicle requiring low consume auxiliaries for higher range autonomy.The issue of low cost fabrication is addressed by impleme
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fifth Framework proposal on 'Assimilation and standardisation of environmentally friendly packaging technologies within the food industry'.

assistant: **Innovation**

The primary aim of this network is to disseminate the spread of eco-friendly, recyclable packaging technologies across Europe with the focus of the project directed towards food packaging materials. The network will achieve this through a Concerted Action network to coordinate RTD activities ongoing within member states. The focus of the network will be towards recycling and waste minimisation in food packaging, which will result in lower production costs and more eco-friendly practices. At present, recyclable food packaging is a rapidly developing field which is experiencing continuous technological changes and increases in volume. The project will seek to establish new technologies and practices in the field of recyclable packaging and raise know-how throughout European industry. This will be achieved by combining the ongoing R&D activities with other initiatives that will embrace education, review of legislation and technology transfer.