RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fifth Framework proposal on 'European research programme for improved vaccine safety surveillance'.

assistant: **Innovation**

The overall objective is to provide a scientific basis for improved vaccine safety surveillance. Problems in current passive reporting systems will be explored; Further objectives include development of case definitions for Adverse Events Following Immunization (AEFI); production of guidelines for data collection; development of a vaccine register model; comparisons of active and passive surveillance; and production of training materials. Work plan: A systematic review of Aegis after MMR will be performed. Problems in the current passive reporting systems will be analysed utilizing recently compiled European database. Expert groups will develop case definitions for significant AEFI, and the definitions will be validated. Essential properties of vaccine registers will be analysed. The conclusions from these achievements will be used in a prospective study of active and passive reporting systems. All results will be combined in an analytic overview, and also used for electronic training materials directed to professionals in vaccine-vigilance.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fifth Framework proposal for the project 'Molecular mechanisms controlling pancreas organogenesis and differentiation of pancreatic cell types'.

assistant: **Objectives**

The major goal of this proposal is to identify genes witch play an important role in pancreas development and to elaborate a model describing pancreas organogenesis. This will be achieved in four stages :i) cloning of novel putative regulatory genes from pancreatic cells,ii) analysis of the expression pattern of these novel genesiii) determination of the function of the new genesiv) study of the regulatory circuits existing between these factors. These tasks will be performed by taking advantage of three complementary biological models :i)mammalian pancreatic cell lines,ii) zebrafish andiii) mouse. Also, we will determine whether differentiation of mouse embryonic stem cells into pancreatic beta cell type can be achieved through the controlled expression of key pancreatic factors identified during this project . This proposal is likely to have profound impacts for the development of new diagnostics tools or of new therapies for diabetes.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Integrated decision support tool for retrofit and renewal towards sustainable districts' (ECODISTR-ICT).

assistant: **Concept**

The ECODISTR-ICT project aims at developing an integrated decision support tool that facilitates decision making on the retrofitting and renewal of existing districts and its composing buildings. It connects the main decision makers in urban district transformation programs, acting from different perspectives, with different time scales, to reach a coordinated approach that joins building retrofitting with district renovation. This coordinated approach adds the benefits of the economies of scale on a district level and allows for optimization and prioritization of decision-making. The tool provides trustworthy insights on retrofitting and renewal projects, the associated costs and benefits during the life cycle of the buildings and the impacts of these on resource efficiency, social aspects, indoor and outdoor quality of buildings and districts, and environmental concerns.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'HUMAN TRANSITIONAL PATHWAYS TOWARDS FOOD PRODUCTION IN NORTH AFRICA: TECHNOLOGICAL AND ENVIRONMENTAL SIGNATURES' (AGRINA).

assistant: **Concept**

The origin of food production is a key theme in North African pre-/protohistory. In recent years the orthodox model, that domestic plants and animals were introduced by maritime Neolithic colonists from the Near East, has been challenged, and a component of autonomous development independent of the Near East acknowledged. However, there remains considerable uncertainty about the nature and extent of, and interplay between, internal and external dynamics in the beginnings of food production across North Africa.Although it is commonly accepted that domestic plants and animals from the Near East (wheat, barley, cattle, sheep/goats) were introduced into North Africa in the Early and Middle Holocene (c.9000-4000 cal. BC), a period of profound climate change, when and how these migrations occurred remain extremely uncertain. The aim of the proposed project is to a make a significant contribution to resolving this uncertainty through innovative methodologies in artefact analysis.The project will focus on three case study areas, to investigate and compare forager-farmer interactions and processes of Neolithization in contrasting ecosystems: Mediterranean (Gebel Akhdar), arid (Egyptian Western Desert) and lacustrine (Fayum). It will take advantage of current fieldwork programmes by European teams collecting high quality palaeoclimatic and palaeoenvironmental data essential for understanding human group activities in this period of significant climate change. It will investigate the chronology and location of the first appearance of the Levantine domesticates in North Africa, their subsequent spread and the cultural interactions involved in these processes, through a multidisciplinary approach based on Accelerator Mass Spectrometry dating of domesticated botanical and zoological
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Education through Characters with emotional-Intelligence and Role-playing Capabilities that Understand Social interaction' goes beyond current state-of-the-art under Sixth Framework.

assistant: **Innovation**

e-CIRCUS aims to develop novel conceptual models and innovative technology to support learning through role-play and affective engagement for Personal and Social Education (PSE) involving complex social situations. It has the following objectives:<br/>1. To develop models of narrative engagement and empathy for social and emotional learning processes through role-play. 2. To support affective engagement in social and emotional learning through new methods of interaction supporting both spectator and actor roles.3. To create an innovative architecture to enable educational role-play for social and emotional learning in virtual environments populated by synthetic characters with autobiographical memory, individual personalities and attributes.4. To create a VLE for emotional and social learning through developing showcases for educational role-play: one on anti-bullying education and one on intercultural empathy.5. To optimize user involvement in design and development through a classroom-based, curriculum-focused participatory design approach. 6. To carry out a comprehensive evaluation framework including a longitudinal study to assess impact and effectiveness.  7. To disseminate widely the results of the project and seek opportunities for exploiting the results of the project.<br/>By delivering technology that integrates affect with cogniton, it will meet the action line objective To contribute to new understandings of the learning processes by exploring links between human learning, cognition and technologies.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Security of software services of mobile systems' to be submitted under Sixth Framework.

assistant: **Abstract**

The objective of S3MS is to create a framework and technological solution for trusted deployment and execution of communicating mobile applications in heterogeneous environments. S3MS would enable the opening of the software market of nomadic devices (from smart phones to PDA) to trusted third party applications beyond the sandbox model, without the burden of roaming trust infrastructure but without compromising security and privacy requirements.A contract-based security mechanism will lie at the core of the framework. A contract is a claim by a mobile application on the interaction with relevant security and privacy features of a mobile platform. This contract should be published by applications, understood by devices and all stakeholders (users, mobile operators, developers, platform developers, etc.). The contract should be negotiated, and enforced during development, at time of delivery and loading, and during execution of the application by the mobile platform.The new paradigm will not replace, but enhance today's security mechanism, and will provide a flexible, simple and scalable security and privacy protection mechanism for future mobile systems. It will allow a network operator and a user to decide what an application is allowed to do, prevent bad code from running, and allow good code to be easily designed and deployed.The new paradigm of security-by-contract affects the entire life cycle of mobile applications and services: Contracts must be accommodated in high level design of security and privacy requirements of applications and mobile platforms, programming languages for the formulation of contracts must be developed, compilers must be modified to produce executable contracts for a piece of software, loaders must be aware of the static contract information
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Degoo backup – the first back-up service based on dynamic routing of transfer data to data centres', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

This innovation project will create Degoo Backup, a novel cloud backup service that will redefine the established business model on the international cloud backup market. The idea is to create the service that breaks the monopolized position of the multinational players, such as Google, Amazon, Microsoft or Apple, by changing their status from the players that control the market for cloud infrastructure as a service (IaaS) and thus dictate cloud backup prices to providers of storage space that have to compete with smaller and national players.  This will be enabled though a novel functionality for dynamic, rule-based distribution of data to the data centres where the data is stored.The key targeted users for the service with the new data routing functionality are private individuals who need a low-cost, fast-uploading, secure and reliable service for cloud backup of digital content. Users seek a solution for the problem of dynamically expanding size of their digital data and growing need for large storage capacity. The commercial potential of Degoo Backup lies in the opportunity to accelerate the growth of the international backup market with the needs of the end-uses as the major flywheel.The Phase 1 feasibility assessment will develop a business plan that will guide the upcoming technological efforts and commercialisation/exploitation efforts. The implementation, demonstration and testing of this new functionality will take place in the Phase 2 project. The EU aims at regulating this market through its data protection directive and the data protection regulation. The project supports those efforts by delivering the first cloud backup service that truly enables the European citizens to store their data in Europe, in full compliance with the applicable rules and regulat
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Conjugation of NAD-capped RNAs to proteins by ADP-ribosyltransferases to generate RNA therapeutics' in the context of a Horizon Europe call.

assistant: **Objectives**

Background: We discovered that NAD-capped RNAs can be covalently attached to specific target proteins by the phage T4 ADP-ribosyltransferase (ART) ModB, which we term RNAylation.Scientific problem: RNA therapy has almost limitless yet unexplored potential. Its translation into the clinics, however, requires optimal RNA delivery with high RNA stability, efficient cellular internalisation and precise target affinity. Hypothesis: Protein-RNA interactions are ubiquitous and central in biological control. I hypothesise that conjugating a NAD-capped nucleic acid to a protein catalysed by an ART generates a novel biomolecule – the RNAylated protein – with unique functionalities. The covalently linked protein or nucleic acid can trigger a directed intracellular delivery, where both, the protein and the nucleic acid, can become functionally active. This allows targeted modulation of translation or transcription, or editing. RNAylated proteins may provide a platform to engineer the cell and represent a starting point for the creation of next generation RNA therapeutics.Objectives:This project aims to establish RNAylated proteins as a fundamentally novel tool to regulate cellular processes. In objective 1, we will define the design principles for RNAylated proteins, allowing to control cellular processes. In objective 2, we will develop delivery strategies to transfer RNAylated proteins in specific cell types and allow for precise cellular localisation. In objective 3, we will combine the design and delivery principles for RNAylated proteins and apply them to target the tumour suppressor protein p53 by regulating translation, transcription or by editing.Impact: This project will develop RNAylated proteins as next generation RNA therapeutics and deepen our understanding of how a fu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Assembly guided by particle position and shape' to be submitted under Horizon 2020.

assistant: **Abstract**

The controlled fabrication of nano/micro metre-scale objects is without doubt one of today’s central goals in science and technology - one essential for the development of nanotechnology and the expansion of microtechnology. Because said objects fall awkwardly between the sizes that can be manipulated by chemistry and those that can be manipulated by conventional manufacturing, the most promising strategy for their fabrication is self-assembly, that is, the autonomous organization of components into structures without human intervention. Indeed, self-assembly promises to revolutionise the way we fabricate industrial and consumer goods, building technologies and optical devices. However, it has limitations: generating complex responsive devices via this method is difficult and hence it is not well suited for producing structures for high-end applications (switchable metamaterials, nano/micro robotics...). Furthermore, the process is inherently inflexible; whilst its components spontaneously assemble, they do so to form only a single set of structures and they must be arduously taylored and selected ad hoc to achieve even this. Recently, I have proved the concept of a new self-assembly method that is not subject to these limitations and therefore has the potential to expand the application base of self assembly into previously untapped areas - such as microrobotics. I have christened this process APPS (assembly guided by particle position and shape). APPS is still in its infancy and this proposal will establish its design rules for the first time and then apply them to make jointed actuators, connected with custom DNA structures, that will have unprecedented and programmable performance on the micron scale.


**Keywords:** Self assembly, magnetic particles, magnetic actua
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Scalable Modelling and Model Management on the Cloud'.

assistant: **Concept**

As Model Driven Engineering (MDE) is increasingly applied to larger and more complex systems, the current generation of modelling and model management technologies are being pushed to their limits in terms of capacity and efficiency, and as such, additional research is imperative in order to enable MDE to remain relevant with industrial practice and continue delivering its widely recognised productivity, quality, and maintainability benefits. The aim of MONDO is to tackle the increasingly important challenge of scalability in MDE in a comprehensive manner.<br/>Achieving scalability in modelling and MDE involves being able to construct large models and domain specific languages in a systematic manner, enabling teams of modellers to construct and refine large models in a collaborative manner, advancing the state-of-the-art in model querying and transformations tools so that they can cope with large models (of the scale of millions of model elements), and providing an infrastructure for efficient storage, indexing and retrieval of large models. To address these challenges, MONDO brings together partners with a long track record in performing internationally-leading research on software modelling and MDE, and delivering research results in the form of robust, widely-used and sustainable open-source software, with industrial partners active in the fields of reverse engineering and systems integration, and a global consortium including more than 400 organisations from all sectors of IT.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'Psychological determinants of household financial decision making'.

assistant: **Concept**

The overall objective of my research is to gain a better understanding of how households view their future and make decisions about saving and borrowing. The objective is motivated by the increasing concern for the standard of living of future generations of elderly and by the so-called debt crisis which appeared in many European countries in the beginning of the nineties, characterised by a large number of households with debt problems. I wish to study the effects of psychological variables on household saving and borrowing behaviour. I will also address methodological challanges related to the studies of household decision making. To achieve this goal, I will use panel data available at CentER (the VSB-data) as well as collecting qualitative and quantitative data myself. All the variables in focus are measured by multiple items, and the hypotheses will be analysed by using structural equations modelling.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Creating links to speed-up innovation in the bio economy' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

BioLinX will bridge research and innovation efforts in the bioeconomy by building three large clusters in Europe and initiating within them a range of powerful linking and innovation acceleration processes.  The BioLinX partners have leading roles in the bioeconomies of South West Netherlands and Flanders, the Nordic Countries and Northern Italy and in the lignocellulose, agro- and agro-waste feedstock sectors.  The partners are all pioneers of systematic innovation management and cluster acceleration practices and between them have leading roles in over 45 current or recent collaborative bioeconomy projects.    From this strong starting point they will select sixty or more FP7 and Horizon 2020 biobased projects from all stages of the value chain, form the BioLinX clusters and develop among them brokerage, collaborative innovation and business acceleration dynamics.  Specific objectives are: 1. Selecting and scouting more than 60 high potential bio-economy projects,2. Developing a network of key regional bioeconomy clusters (i.e. RIS3 regions or equivalent) covering 3 geographical regions (north, central, south)3. Analysing, clustering and focusing selected FP7 and H2020 projects as well as the network of RIS3 bio-economy regions,4. Implementing  the Innovation Linking & Support Programme consisting of activities focusing on Brokerage and Innovation incubation, Business development, finance and funding, Identifying and sharing good practices and Advocacy, communication and dissemination.