RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Fish Flow Innovations Tidal Turbine' under Horizon 2020.

assistant: **Concept**

Fish Flow Innovations (FFI) wants to commercialize a fish friendly tidal stream turbine that converts ocean currents into electricity. The turbine can be fixed mounted on a seabed,  tethered/moored to a seabed and/or buoyant, or float on the water surface or in mid water. The turbine is designed and constructed to survive in the harsh conditions offshore, and able to efficiently produce electricity in water flows between 3 and 15 m/s without the need for pitch adjustable blades for bi-directional functionality. The turbine has an integrated gravity based support structure, avoiding the need for expensive underwater support structures. The turbine can be deployed in all planned tidal locations worldwide. The main objective of the innovation project is to demonstrate and reach market readiness (TRL 9). At the end of the project (January 2019) through certification and an output performance warranty, a commercially viable levelized Cost of Energy of 10 c€/kWh will have been demonstrated in real-sea conditions (provided in the Tidal Technology Center Grevelingendam  in The Netherlands).
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Trust and Contract Management framework enabling secure collaborative business processing in on-demand created, self-managed, scalable, and highly dynamic Virtual Organisations' in the context of a Sixth Framework call.

assistant: **Objectives**

TrustCoM will develop a framework for trust, security and contract management in dynamically-evolving virtual organisations. The framework will enable secure collaborative business processing within on-demand created and self-managed, dynamic collaborative networks of businesses and governments built on top of the emerging convergence of Web Services, agent and Grid technologies.Recent years have seen an unprecedented acceleration in the evolution of the Internet as the technological vehicle underpinning the expansion of service provision and inter-/intra- enterprise integration in all market sectors. This brings about the prospect of ad hoc integration of systems across organisational boundaries to support collaborations that may last for a single transaction or evolve dynamically over many years.  This sets new requirements for scalability, responsiveness and adaptability that necessitate the on-demand creation and self-management of dynamically evolving virtual organisations (VO) spanning national and enterprise borders, where the participating entities (enterprises or individuals) pool resources, information and knowledge in order to achieve common objectives.The mission of the TrustCoM integrated project is to provide a trust and contract management framework enabling the definition and secure enactment of collaborative business processes within Virtual Organisations that are formed on-demand, are self-managed and evolve dynamically, sharing computation, data, information and knowledge across enterprise boundaries, in order to tackle collaborative projects that their participants could not undertake individually or to collectively offer services to customers that could not be provided by the individual enterprises.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fourth Framework proposal on 'Client-server rule induction technology for industrial knowledge acquisition from large databases'.

assistant: **Innovation**

The basic premise for the project is the real business need for tools to enable in situ data mining against large databases in a client-server environment. The technological basis for the work of the project is Attar Software's mature, widely proven XpertRule induction technology and its newly released XpertRule Profiler client-server induction technology which is aimed specifically at the data warehousing marketplace.The objectives of the project are to:demonstrate the potential for adding value to the info assets of organisations in different sectors through effective client-server induction from large corporate data warehouses;develop and demonstrate an advanced client-server induction system capable of supporting efficient, effective data mining of large databases in business environments;generate prototypes of a series of enhancements to Attar Software's XpertRule Profiler product which are enabled by HPC technology and which are commercially exploitable during the lifetime of the project;generate a body of large-scale data mining experiences, from both the financial and pharmaceutical wholesale sectors, which will form the basis for generic dissemination and specific marketing activities.Product technology based on the results of the project will be rapidly exploited by Attar Software both during and after the timeframe of the project. Products based on the software developed in the project will have the potential to make a significant impact on a huge worldwide marketplace which is eager to invest in demonstrable capabilities. The end-users will provide advice and guidance to Attar Software to assist the exploitation process.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'ESO Fellowship Programme for ALMA' (ESO-FEL-ALMA08), addressing dissemination and exploitation.

assistant: **Impact**

The Atacama Large Millimetre/submillimetre Array (ALMA) is the major global project for ground-based astrophysics currently under construction. Europe, through the European  Organization for Astronomical Research in the Southern Hemisphere (ESO), is one of the three major partners of this project.  ALMA will start Early Science operations in 2010 and Full Science operations in 2012. When completed, ALMA will allow astronomers worldwide to carry out transformational science and it will be the leading facility of its type in the foreseeable future. To exploit the full scientific potential of this revolutionary instrument, Europe has to train and develop a new generation of young researchers and strengthen the connections between the various institutes throughout Europe where there are already strong groups of millimetre/submillimetre astronomers. We believe that the best way of achieving this goal is to promote the scientific development and mobility of young researchers through a fellowship programme. ESO has been running a highly successful Fellowship Programme for the last three decades. In the framework of this programme fellows come to the ESO premises to carry out top class scientific projects of their choice and to learn and develop additional skills related to the various aspects of of the organization (from science operations to instrument development and public outreach). We propose to extend our existing Fellowship Programme in Garching and offer the possibility to Fellows to carry out the research programme of their choice either at the ESO headquarters or in any of the European institutes that are participating in the European ALMA Regional Center. The proposed extension of the ESO Fellowship Programme will enhance the transnational mobility and transfer of k
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Ecological and Economic Valuation of Ecosystem Services - An Integrated Approach' (2002-2006).

assistant: **Concept**

Ecosystems provide services, which contribute to the satisfaction of human needs in many ways and deliver irreplaceable life support functions on which human life as a whole rests. Furthermore, ecosystem services exhibit the two characteristic properties of economic commodities:(i) Their consumption increases human utility and(ii) they are scarce as both the natural resources and the funds to preserve them are limited. To treat the trade-off between the economic use of natural resources and further provision of ecosystem services, a valuation of these services is inevitable. There are two distinct approaches to deal with the problem of ecosystem valuation. Among economists economic valuation methods prevail, which focus on the exchange value of ecosystem services. Their common characteristic is that they are finally based on consumer preferences, and do not adequately take account of the internal structure of ecosystems. Ecological valuation methods, mainly advocated by natural scientists and ecologists, derive ecological prices for the ecosystem services by a cost-of- production-approach. They model the complex interrelationship between the different species and the inanimate nature within the ecosystem. Their common characteristic is the neglecting of consumer preferences. As the existing methods for the valuation of ecosystem services emphasise either the economic system (economic valuation method) or the ecosystem (ecological valuation method) the main objective of this project is to provide the theoretical foundations for a new method of valuation of ecosystem services, which deals simultaneously with the economic system and the ecosystem in an equally detailed and balanced way. Therefore, an integrated analytical model will be derived which covers, on the one hand
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Novel integrated high speed fibre production' (1994-1998) under Fourth Framework.

assistant: **Objectives**

Chemical industry and engineering companies have a strong need for proccss innovations aiming at cost reduction and new product development. Cheap products from outside the EU menace employment in several business areas. The sales for textured fibre production alone in the EU is about 1 000 million ECU per year, not including sales for machines and final textile products. The target of this project is a sophisticated new integrated process for a textured, bulky chemical fibre yarn type that will not only reduce manufacturing costs but generate a decisive lead in innovative processing know how and new products. State of the art are two processes, i.e. melt spinning and in a separate step conventional filament texturing to generate the yarn volume. The integration of both production steps gives a leap forward with respect to economy and potential applications. The technological progress will be a substantial advantage for the European industry with regard to its global competitors. The characteristics of the new integrated process and its products are as follows  a cheap bicomponent melt spinning unit combined with  a high speed texturing unit based on the new latent crimp bicomponent yarn  application of Polyester (PET) and new polymer types, e.g. PTT or PBT  production speeds higher than 2000 m/min, preferably up to 4000 m/min (i.e. 2,2 to 4,4 times higher than conventional texturing speeds)  a new interesting yarn characteristic with a crimp level > 10 %  new products with application in technical end uses (e.g. transportation, automotive, etc.) and textile enduses In this project Barmag, Ems Inventa and FEG, i.e. the engineering and machine manufacturing companies, go ahead in order to provide components for the new integrated process. The man made fiber producing com
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Oncolytic adenoviruses expressing monoclonal antibody trastuzumab for treatment of Her-2+ cancer' (TRASTUZUCRAD).

assistant: **Concept**

Metastatic breast, ovarian, gastric and esophageal cancer are currently incurable and therefore require new and innovative treatment approaches. The objective of this project is to construct oncolytic adenoviruses that code for trastuzumab (HerceptinR), a monoclonal antibody against tumor associated receptor Her2. Intravenous trastuzumab is already widely used for treatment of Her2+ breast cancer, and is being actively studied for other tumor types that frequently feature Her2 amplification, including ovarian, gastric and esophageal cancer. We hypothesize that expression of the antibody from a virus will result in production of high, sustained concentrations of functional trastuzumab in situ. In comparison to conventional intravenous delivery, this might results in enhanced anti-tumor activity but reduced systemic exposure and side-effects. Further, a single injection of the virus might result in prolonged production of trastuzumab which might be cost-effective as intravenous trastuzumab is expensive. The viruses will be targeted for effective delivery to tumor cells through viral capsid modifications, and oncolytic cell killing will proceed only in p16/Rb pathway mutant tumor cells. Trastuzumab production will be coupled to virus replication. Further, trastuzumab is secreted into the surrounding tumor tissue for an effective “bystander effect”, ie. killing of neighboring tumor cells. In summary, we hypothesize that this approach will result in tumor cell killing through viral oncolysis, the anti-tumor activity of trastuzumab, and the potential synergy between the approaches. Further, high local concentrations might result in anti-tumor efficacy superior to efficacy seen with intravenous trastuzumab. These developments might eventually result in increased treatment opti
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Pv modules optimised for building integration' (1994-1998).

assistant: **Concept**

The aim of this project is the development of new designs of PV modules optimised for their use as building elements, with a common characteristic: the light transmitance through the module structure to allow the natural daylighting of inner rooms and offices. Between the possible applications of this kind of modules, three building integration applications have been selected: glazed facades, windows and grazing atria. Conventional solar cells will be used, considering the three technologies of Silicon cells: mono-, multi-crystalline and amorphous Silicon solar cells. The associated partners will focus their efforts in the optimisation of PV modules for these applications taking into account several inter-related subjects currently not well characterised under the operating conditions of building integration systems: the electro-optical, thermal and luminous (light transmitance) behaviour of modules. These aspects have a relevant impact on the comfort of the indoor environment and the final-user's quality-of-life. The research on these subjects will conduct to an optimisation process of PV module designs, where parameters such as, e.g., the cell size and separation (for c-Si cells), the device thickness/transmission ratio (for a-Si), the electrical interconnection, the module structure based on a double glass configuration, the passive-cooling methods, the support structures and installation methods or the user safety will be especially considered, without neglecting the building aesthetic and a cost-effective design. To analyse these important subjects, two European R&D centres (CIEMAT and ECN) and three PV module manufacturers (ISOFOTON, ASE and PST) will join their experience and facilities in this RTD project. The workprogramme will be developed in four consecutive
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'The dark side of evolution:  the deleterious mutational landscape of RNA viruses' (RNAVirFitness), addressing dissemination and exploitation.

assistant: **Impact**

Mutations are fundamental drivers of evolution. Characterizing how mutations affect fitness is critical across diverse fields: from pathogen biology, to human genetic diseases, and models of population extinction. RNA viruses, notorious for their high mutation rates and rapid generation times, are ideal models for studying the effects of mutations. To date, deleterious mutations (i.e., mutations with a fitness cost) have been understudied as compared to beneficial mutations, mainly since it has been technically unfeasible to sequence each single rare deleterious mutation. Using novel next generation sequencing (NGS) techniques, we and others have recently overcome this gap, and shown that an appreciable proportion of viral genetic diversity is a consequence of a multitude of rare deleterious mutations. Here, we suggest investigating the distribution of fitness effects (DFE) across a diverse array of RNA viruses, spanning representatives of each class of major human pathogens, both in vivo (in patients) and in vitro (in cell culture). Next, we will focus on genetic linkage and context-dependent fitness effects of mutations. We postulate that over- and under-represented sequence contexts may represent signatures of host anti-viral activity. Finally, we will investigate how the DFE changes following an environmental perturbation (physical and metabolic changes, tissue type, and sex of the host). We will explore how the accumulation of deleterious mutations following rapid perturbations may lead to the extinction of the viral population, and how this can be used as a novel strategy to tackle viral epidemics. To this end we will integrate state-of-the-art NGS, population genetics modelling, and reverse genetics validation. Beyond their contribution to evolutionary biology, w
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Unraveling interaction networks of ammonia- and nitrite-oxidizing microorganisms'.

assistant: **Objectives**

Microbial interactions drive global biogeochemical cycles and shape functionality and productivity of ecosystems. Autotrophic nitrification is a prime example for a mutualistic interplay of two functional groups. In fertilized soils, nitrification contributes to emission of the ozone-depleting greenhouse gas nitrous oxide and nitrogen (N) run-off into surface waters, resulting in eutrophication and algal blooms. In contrast, in biological wastewater treatment it initiates the removal of excess N to reduce the N load into the environment. In their cross-feeding interaction, ammonia-oxidizing bacteria (AOB) provide the electron donor for their partner by converting ammonia to nitrite, which is further oxidized to nitrate by nitrite-oxidizing bacteria (NOB). In addition, nitrifiers also interact with heterotrophic bacteria that feed on metabolites released by nitrifiers or attack them in a predator-prey interaction. In this project, I aim to determine factors defining interaction networks of nitrifiers by analyzing the effect of this interplay on the metabolism of the individual allies and by identifying novel interaction partners of nitrifying microbes. I will analyze the metabolic aspects of this interplay in artificially mixed nitrifying assemblages to simplify the complex interaction networks occurring in nature. Using state-of-the-art isolation techniques, I will first isolate novel AOB and NOB cultures from the same environment to obtain true interaction partners. Physiological key features and gene expression patterns of separately grown and mixed cultures of these isolates will be compared to determine the nature and effects of interactions among nitrifiers. In addition, novel interaction partners of uncultured nitrifiers will be identified by analyzing co-occurren
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Uptun: cost-effective, sustainable and innovative upgrading methods for fire safety in existing tunnels', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

The Common Transport Policy is one of the original ingredients of the first European treaty (Treaty of Rome). Tunnels are important in the existing and envisaged transport system. However, the safety of tunnels was put in question after recent fires, which resulted in fatalities, casualties and economic damage. The fires also discouraged tunnel usage in some cases. This adversely affects a sustainable socioeconomic development. The UPTUN project aims at solving these problems.The UPTUN project aims at:1) development and promotion of innovative, sustainable and low-cost measures to limit the probability and consequences of fires in existing tunnels and;2) development and promotion of an integrated evaluating and upgrading procedure, incorporating the innovative measures, for existing tunnels to allow owners, stakeholders, designers and emergency teams to evaluate and upgrade the human and structural safety level.