RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'EKUPD'.

assistant: **Objectives**

Existing large off-road power train applications are dominated by diesel power train solutions. These applications are large fuel consumers and massive CO2, NOX and particulate emitters. Natural Gas reduces CO2 emissions by 20%, NOx by 90% and particulate emissions are removed. Moreover, Natural Gas prices are consistently at a fraction of diesel (25% in 2015). EKU’s proprietary control methods solve the technical barriers that natural gas engines have (e.g., sluggish performance restricted operation ranges), to replace diesel engines. GYBRID is an intelligent, natural gas-electric hybrid solution to facilitate electrification in off-road industrial applications (e.g., tug-boat, trucks, pressure pumps…). It uses natural gas or biomethane as its primary fuel and is supplemented for higher efficient power performance with a smart high energy dense battery array and sophisticated control technology. EKU GmbH develops hybrid industrial power at the leading edge of clean energy, electric motor technology, industrial battery assembly. EKU’s personnel has a strong track of record in the development and commercialization of new radically new horsepower concepts. GYBRID addresses the most important key buying criteria; reduction of operating costs (50%), reduction of downtime (by 80%) and reduction of emissions. For example, for hydraulic pumping trucks, customers save fuel costs of around €1.2M per unit annually, reducing their production expenditures up to 50 % and additionally increasing four times the lifetime of their power drive equipment. The customers can expect a payback within two years EKU, amongst others, was awarded first place in the 2014 Munich Cleantech Innovation Award which recognizes and rewards the best European clean technology venture. The jury rewarded EKU
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Smart Chemical Gas Sensor System Fabricated in Low Cost CMOS Technology with Integrated Electronics and Hybrid Sensitive Layers', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

The objective of CMOSSens is to develop a completely novel generation of miniaturised hybrid gas sensor systems fabricated in industrial CMOS technology by the consortium. For the first time, driving circuitry, signal- processing electronics as well as a microcontroller will be integrated monolithically with the sensor array on chip. The array will be coated with drop-deposited nanocrystalline metal oxides as sensitive layers. Novel evaluation algorithms for signal processing and new packaging solutions or the sensor system will be implemented. Due to its unique characteristics (small size, low price, smart features, CMOS) the system will open up new markets, not considered for sensors yet.Within CMOSSens, the system will be used in four key-applications: monitoring(1) residual oil in compressed air(2) food quality in refrigerators(3) air quality, workplace safety and(4) application in portable electronic noses.Objectives:CMOSSens objectives:(a) to develop and to transfer to the industrial environment the know-how for production of a versatile, miniaturised, integrated chemical gas sensor system, and(b) to use the sensor system in four defined novel applications of direct industrial interest, thus initiating a generation of innovative products with significant market potential (portable electronic nose, residual oil monitoring, food quality in refrigerators, air quality monitoring).The scientific/technological objectives of CMOSSens include(1) realisation of a micro hot plate array,(2) integration of driving electronics on chip,(3) integration of data preprocessing and A/D conversion units on chip,(4) innovative technology for deposition of sensitive layer,(5) implementation of smart features and on-chip microcontroller,(6) development of novel operation features and ev
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Beyond the chromosome: unravelling the interplay between inter-chromosomal genome architecture and mRNA biogenesis' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

In TRANS-3 we will develop the theoretical and experimental framework to understand inter-chromosomal genome structure and activity. Despite advances in sequencing chromosomes and mapping their three dimensional (3D) organization, a full picture of 3D genome structure that details how the borders of various chromosome territories functionally interface one another is still missing. As an analogy, our world map does not indicate most natural corridors or manmade infrastructure that connect countries to one another. Worse, we barely understand how such connections function. My recent work has identified one of the few functional inter-chromosomal (trans) DNA interactions known to date: a splicing factory involving over ten chromosomes and orchestrated by the muscle-specific protein RBM20 around its key target, the TTN pre-mRNA. I hypothesize that this exemplifies how mRNA biogenesis instructs the formation of trans-interacting chromatin domains (TIDs) around mRNA factories, nuclear compartments that facilitate gene regulation. We will test this general hypothesis by dissecting the mechanisms and function of a specific, disease-relevant model: the RBM20 mRNA splicing factory. We will then explore the global impact of these regulations. First (WP1) we will mechanistically assess how mRNA factories form and act through live imaging of the nuclear positioning and alternative splicing dynamics of an RBM20-regulated locus. Secondly (WP2) we will examine the physiological role of mRNA factories by studying the effects of disease-associated mutations in RBM20 and the TTN regulator GATA4, and of genetic variability in TTN regulatory regions. Finally (WP3) we will develop and deploy a novel pipeline to identify, validate, and study new TIDs and mRNA factories through the combinatio
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'PROTECTION OF NEONATAL PIGS FROM VIRUS DISEASE : TARGETED INTRACELLULAR IMMUNIZATION WITH DEFECTIVE VIRAL GENOMES' (1994-1998) under Fourth Framework.

assistant: **Objectives**

Gastrointestinal infections are common in new-born animals in intensive animal husbandry, and pose a serious economic threat. While antibacterial agents have been very effective, antivirals have met with ! limited success. This project proposes to use a procedure known as intracellular immunization, in'which neonatal pigs will be inoculated with defective (non-infectious) viral genomes in order to prevent enteric infections. These defective genomes are small (<=10 kb) and have the unique ability of interfering at the molecular level with (i.e. inhibiting) the multiplication of homologous infectious virus, and are known as defective interfering (DI) genomes. In vivo they need be p resent only in a sufficient number of cells to reduce infection and hence allow the host's defence mechanisms to overcome the virus.Intracellular immunization will be specifically tarqeted to tissues normally infected by the viral pathogen, using virus-like particles (VLPS) with envelope proteins that confer the required cell tropism.Benefit will be mediated by two complementary mechanisms: (1) direct interference with virus multiplication in the cell which is effective immediately after administration and (2) induction of a conventional protective immune response which is effective after a few days, in a; manner analogous to human neonates who can be successively immunized by gut infection with oral poliovirus vaccine. Intracellular immunization will be developed for viruses of neonatal pigs . transmissible gast-; enteritis viru- (TGEV) and porcine epidemic diarrhoea virus (PEDV). Inj 1994 these viruses were major contributors to enteric and respiratory ! infections which cost the EU about 766 million ECU, (51,*' of an industry worth 15000 million ECU, and comparable to that of North America).
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Foundations of Perception Engineering' (ILLUSIVE).

assistant: **Innovation**

Virtual reality (VR) technology has enormous potential to transform society, especially as the world faces unprecedented challenges of remote work and social distancing brought on by COVID 19. Through telepresence it uniquely enhanced health care, collaborative design, education, and social interaction, all from a distance. Further benefits arise by incorporating synthetic models, which advance computer interfaces, data visualization, and immersive storytelling.In spite of its potential, the VR industry has struggled through hype cycles as devices built from co-opted component technologies fail to meet the expectations of each generation. As an industry leader in Huawei and early Oculus VR, I concluded that the struggle is largely due to the lack of a rigorous foundation that draws from scientific disciplines of perceptual psychology, neuroscience, and human physiology. I propose to reduce the gap between engineering and these human-centered sciences by developing a new field of perception engineering. In this pioneering view, the object being engineered is the illusion itself, and the physical devices that achieve it are auxiliary.This project focuses on developing mathematical foundations for VR that unify engineering concepts from robotics and control theory with their biological-system counterparts, especially predictive coding and the free energy principle. A cornerstone is von Neumann-Morgenstern information spaces, introduced for games with hidden information, which I have leveraged for fundamental problems in robotics throughout my research career. Our team will include experts from VR, neuroscience, perceptual psychology, robotics, control theory, and pure mathematics. The work will lay a foundation for principled engineering approaches to design, simulation, p
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Large section ceramic injection moulding' to be submitted under Fourth Framework.

assistant: **Abstract**

Research objectives and content The objective is to combine the following areas of expertise in ceramic injection moulding: i) control over the solidification stage to eliminate defects in large sections (Brunel University) ii) catalytic removal of organic vehicle below its melting point (BASF) Put together, these two approaches pave the way for the direct injection moulding of large section ceramic mouldings; an achievement that presently eludes the industry worldwide. The BASF process allows the removal of organic vehicle in the solid state by a shrinking unreacted core mechanism. This will be modelled to deduce reaction rate constants and effective diffusion coefficients which will be compared with theoretical values in order to deduce the gas pressure in a large fine particle assembly during binder removal. The moulding techniques which will be applied allow the solidification process to be controlled so that shrinkage voids and cracks can be prevented. Taken on their own, neither individual approach can arrive at a final sintered large section ceramic moulding but taken together the possibilities are considerable. Training content (objective, benefit and expected impact) This programme involves a very wide experimental and theoretical base incorporating ceramic science, polymer science, injection moulding, heat transfer, characterisation of defects, reaction kinetics and gas transport. It requires the student to be adventurous in the acquisition of wide ranging skills. Links with industry / industrial relevance (22) This project is a collaboration between Brunel University and BASF and the initiative or it came from the industry. It involves very careful experimental design to address the aetiology of defects coupled with the systematic control of intervention to t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'New safe and cost effective techniques against asbestos risk in build and industrial infrastructures' under Fifth Framework.

assistant: **Concept**

Facing the new need of infrastructure upgrading, decommissioning and rehabilitations, many building owners are confronted with the asbestos risk. Current techniques are expensive and not safe enough for workers health and large works.The aim of the project is then to develop safe techniques for asbestos abatement works providing:- a significant decrease of asbestos removing costs (-25%);- a better protection of the employees of this activity;- a better prevention of pollution risk during the works;- a better and safe management of ACM wastes.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Using viral inhibitors to characterise signalling pathways involved in interferon induction' demonstrating excellence, impact and implementation quality for a Sixth Framework call.

assistant: **Abstract**

The innate immune system is the first line of defence against invading pathogens. The immediate response against viruses involves the secretion of interferon-alpha and -beta, which induce an `anti-viral state and apos; in the infected cell and warn neighbo uring cells of the danger. Double-stranded RNA (dsRNA), a hallmark of viral infection, is a potent stimulus of the interferon response, but the molecular mechanisms involved in dsRNA recognition and subsequent signal transduction have only partially been c haracterised. We aim to identify novel components of the signalling pathways involved in interferon induction, by exploiting the fact that many viruses are able to interfere with signalling pathways that regulate the innate immune response. Large DNA virus es possess a particularly ample repertoire of immuno-modulatory genes. We will screen the genome of vaccinia virus for inhibitors of the interferon response, and identify host proteins that interact with the viral inhibitors. The cellular targets of viral inhibition are likely to be key regulators of the anti-viral response, and we will attempt to characterise their function with respect to known signalling pathways. This project, while aimed at elucidating basic cellular signalling mechanisms, may yield re sults of great medical importance. A more detailed understanding of virus-host interactions is crucial at a time when (re-)emerging infectious diseases and the potential threat of biological warfare pose new scientific challenges. Also, the study of immuno -modulatory proteins may result in the identification of novel therapeutic targets for the treatment of chronic and acute inflammatory diseases. The proposed project would allow the candidate to enter a new field of study at the interface of molecular cell bi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Unlocking the hidden information in char to create a new quantitative toolkit for use in forensic fire investigations' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Fire Investigations are undertaken to determine the origin and cause of fires in housing or commercial properties, to identify whether there may be a need for criminal investigation, to provide information on financial loss and in the case of loss of life to design protocols to protect society. Charring is one of the most obvious products of fire and fire investigators have long attempted to utilise patterns of charring to determine fire origin and cause. However, these have often had to rely on qualitative descriptions of charring as there is no quantitative tool that allows them to measure the degree of charring of wood materials. My ERC StG developed a quantitative method that allows the amount of light reflected from charcoals to be measured toward estimating wildfire behaviour. In FORCHAR (forensic char) I aim to adapt this approach and develop it into an essential tool for use in the fire investigator’s forensic toolkit. Its strength is that it allows quantitative measurements of char properties to be used to interpret the origin and source of fires. The FORCHAR tool will be taken through a series of phases of validation testing to that 1) will provide proof of concept that the approach can be transferred from wildfires to fires in the built environment, 2) will allow real-world testing where FORCHAR will be utilised in real fire scene investigations via collaborations with industry partners. The aim being to develop a new tool that can be used to improving fire safety protocols toward preventing the loss of life.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Do early stone tools indicate a hominin ability to accumulate culture?' (STONECULT), addressing dissemination and exploitation.

assistant: **Impact**

Cultural – not genetic – adaptations have allowed humans to colonise the planet. While discovering the roots of human culture has been described as one of the 125 most pressing scientific questions of our time (Science, 2005), it remains unclear when such forms of culture first arose in our lineage. Previous research has argued that similar social learning mechanisms underlie modern human as well as early hominin technology. But the latter shows periods of stasis – suggesting the underlying mechanisms were different. A better model for early hominins might be living non-human great apes. Instead of copying the behaviour from others with high fidelity (as modern humans do), ape approaches seem to be based on socially mediated individual reinventions (latent solutions; Tennie et al. 2009). Unlike high fidelity copying, latent solutions do not lead to 'cumulative cultural change', in which technological changes accrue over generations. Latent solutions are thus a core candidate to account for early hominin stone tools because, among other things, they provide an explanation for their stasis. Using both a top-down and a bottom-up testing approach, STONECULT will experimentally test whether early stone tools are manifestations of cumulative culture – currently the null hypothesis in the field – or whether they are best accounted for with the latent solutions model. That is, STONECULT will evaluate whether early stone tools were more similar to modern ape or modern human technologies. The outcomes and conclusions of STONECULT will therefore inform several fields at once (e.g. anthropology, archaeology, comparative psychology, ethology and primatology). This proposal is the first to test the new latent solutions account of early stone tools. If its predictions are confirmed, t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Excelling Human-Centric Collaborative Ecosystems for Smart Digital Transformations in CCIs' (EXCENTRIC) targeting Horizon Europe.

assistant: **Abstract**

EXCENTRIC - Excelling Human-Centric Collaborative Ecosystems for Smart Digital Transition in CCSI – supports the digital transition aimed at sustainable and responsible growth in the European Cultural and Creative Sectors and Industries (CCSI). It addresses underutilization of data in the daily operations of specific experience sectors: live music, festivals, theatre, and museums. These sectors are distinguished by their capacity to create value by providing audience-centric intangible cultural experiences. EXCENTRIC develops and implements a Collaborative Data Practice through the execution of four sector-specific and two cross-sectoral pilots under real working conditions. By co-designing, testing, and equipping organizations within experience sectors with operations-centric smart data infrastructure and tools, we can effectively integrate data-driven innovations into their strategic operations in programming, pricing, resource management, and audience engagement. The project applies human-centric principles by actively involving the creative workforce’s needs, skills, and interests of pilot organizations and their extended network in the tools’ development processes. It builds organizational capabilities, data literacy, and skill sets to enable the adoption, diffusion, and customization of digital tools, and supports sustainable innovation beyond the project’s duration. At the policy level, EXCENTRIC will formulate evidence-based recommendations for successful digital transformation by employing innovative practices and identifying relevant metrics based on pilot results. The project’s unique approach pioneers the concept of Collaborative Data Practices in the CCSI, which has proven effectiveness in pharma, energy, and logistics. It aims to break down silos within th