RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'MidFrontal Cortex Theta Oscillations: Causes and Consequences' (2014-2020) targeting Horizon 2020.

assistant: **Abstract**

While reading this text, pat your head and rub your stomach (if someone sees you, tell them it's OK; you're doing science). Right now you are engaging in an action that must be actively monitored and quickly adjusted to avoid making mistakes. Over the past five years, my collaborators and I discovered that there is a specific pattern of brain electrical activity that occurs during response conflict—competition between multiple conflicting actions when a mistake could be made. This brain activity is observed over the midfrontal cortex (MFC) and is characterized by oscillations at around 6 cycles per second (the theta band). MFC theta is a highly statistically robust marker of the neural networks involved in action monitoring and behavior adjustments, correlates with single-trial reaction time, and predicts how well people learn from mistakes. Despite these robust findings linking MFC theta to action monitoring, the significance of MFC theta for how neural microcircuits actually implement action monitoring and adjustments is unknown. In the ERC research we will use computer simulations and rodent models to understand how different types of neurons in different cortical layers might use action potentials and oscillations to implement action monitoring. The results will help us understand how the brain monitors behavior and avoids mistakes, and will also give insight into neural microcircuit organization as it relates to higher cognitive function. While developing these computer simulations and rodent models, we will also take our human research to the next level by asking: If action monitoring in the MFC is supported by theta oscillations, does this mean that our actions, and our ability to monitor and adjust them, occur with theta rhythmicity? To answer this question, we
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'THERMAL TRANSPORT IN CORRELATED MATERIALS' in the context of a Sixth Framework call.

assistant: **Objectives**

The goal is the physics of strongly correlated systems (SCES) using the heavy fermion matter. New materials in the last decade appear with unexpected properties. They were an important boost in the development of theoretical concepts. As excellent crystals can be grown, they are particularly suitable for the studies of low temperature properties. The simplicity in the complexity is that they are governed by their heavy fermion quasiparticles. Fine continuous pressure or magnetic field tunings open the possibility to explore different ground states as the cascade from antiferromagnetism (or ferromagnetism) to paramagnetism with often interplay with superconductivity or metal insulator transition.   Our main purpose is to perform a new generation of transport measurements (electric and thermal) to give a sound basis on the role in instabilities of magnetism (spin and orbital ordering or dynamics) and charge localisation (Fermi surface) The programme involves a new instrumentation:  - thermal transport under pressure (P) using the pressure expertise of CEA/SPSMS laboratory  - very low temperature thermal conductivity down to 10mK with the very low temperature knowledge of CNRS/CRTBT.  It will extend the potentiality of high pressure techniques. The P studies will focus on quantum magnetic and superconducting instabilities on cerium, ytterbium, samarium and uranium compounds. The thermal conductivity experiment will concentrate on the determination of new superconductors (order parameter, successive phases).The complementary between Tokyo and Grenoble will favour also to explore new problems of low dimensional magnetism. Our results will lead to develop high pressure techniques, to precise the link between sensitive transport probes and microscope one and to new information
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Multipotential and monopotential stem cells as vector for somatic gene therapy of human diseases' demonstrating excellence, impact and implementation quality for a Fourth Framework call.

assistant: **Abstract**

Despite the enormous progress achieved in the development of gene transfer technology over the last 10 years, the widespread application of somatic cell gene therapy for genetic and acquired diseases is still limited by the kinds and numbers of available target cells. That is, the difficulty of isolating and expanding lineage and tissue-specific stem cells is now the single most important limiting factor in gene therapy. Our goal is to obtain such specific stem cells by selecting and expanding in-vitro stem cells of mouse and human origin -- the former being essential for laboratory investigation, the latter for therapeutic application. Specifically, we propose the following lines of research: 1. The feasiblity of deriving various types of lineage-committed stem cells fro mouse embryonic stem (ES) cells will be investigated. 2. From specific human and mouse tissues and organs, we will isolate stem cells committed to the lymphopoietic, megakaryopoietic, myogenic, lungepithelial, keratinocytic, and neural (mouse only!) lineages. 3. Using appropriate markers and animal models in which to evaluate survival, expansion, and differentiation potential in-vivo, we will assess the possibility of utilising such lineage- committed stem cells as vehicles for somatic gene therapy. We wish to make it clear that we will not produce and/or utilise human ES cells. Apart from the controversial nature of any such undertaking, we believe that it will never be ethically acceptable. Actually, even the mouse ES cell system will only be used in this project for the production of committed lineage-specific stem cells. The pivotal technology in the entire project is based on the possibility of conditionally immortalising stem cells of different tissues and organs. For this purpose, we will utilis
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Accelerated design and discovery of novel molecular materials via global lattice energy minimisation' (ANGLE) under Seventh Framework.

assistant: **Objectives**

The goal of crystal engineering is the design of functional crystalline materials in which the arrangement of basic structural building blocks imparts desired properties. The engineering of organic molecular crystals has, to date, relied largely on empirical rules governing the intermolecular association of functional groups in the solid state. However, many materials properties depend intricately on the complete crystal structure, i.e. the unit cell, space group and atomic positions, which cannot be predicted solely using such rules. Therefore, the development of computational methods for crystal structure prediction (CSP) from first principles has been a goal of computational chemistry that could significantly accelerate the design of new materials. It is only recently that the necessary advances in the modelling of intermolecular interactions and developments in algorithms for identifying all relevant crystal structures have come together to provide predictive methods that are becoming reliable and affordable on a timescale that could usefully complement an experimental research programme. The principle aim of the proposed work is to establish the use of state-of-the-art crystal structure prediction methods as a means of guiding the discovery and design of novel molecular materials.This research proposal both continues the development of the computational methods for CSP and, by developing a computational framework for screening of potential molecules, develops the application of these methods for materials design. The areas on which we will focus are organic molecular semiconductors with high charge carrier mobilities and, building on our recently published results in Nature [1], the development of porous organic molecular materials. The project will both deliver no
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Restriction endonucleases and DNA methyltransferases: structures, interactions with DNA and engineering of novel functions' (1994-1998), addressing dissemination and exploitation.

assistant: **Impact**

We have chosen to study type II restriction endonucleases and DNA methyltransferases because they provide a rich source of information about protein-DNA interactions and because they have gained an enormous importance in Molecular Biology due to their applications in recombinant DNA technologies, genome mapping, manipulation of chromosomes and health care. Recent crystallographic studies have revealed novel DNA-binding motifs and new modes of DNA recognition. To understand the precise mechanisms underlying sequence specific DNA recognition, these studies are extended in the present proposal to the development of novel specificities and include structural and biochemical work with mutated proteins complexed with DNA, along with a systematic examination of the roles of individual residues and bases implicated in specific DNA binding. Moreover, biochemical and biophysical methods are employed to understand the thermodynamics and kinetics of DNA binding, and computational techniques are used for modelling protein-DNA interactions. It will be attempted to apply the experience gained from these experiments to the engineering of modified enzymes with altered specificities, focusing on the commercially interesting restriction endonucleases with 8-base pair recognition sequences. The project uses the EcoRV restriction endonuclease and the DNA methyltransferases EcoRV and dam as model systems with the prime objective to explore the possibility of altering their specificities, as this is considered the most informative approach for understanding interactions with DNA and fruitful in terms of potential applications. To this end, the project: a) uses crystallographic studies of the above enzymes or of their variants complexed with DNA b) employs mutagenesis and advanced selection te
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'MAterials for Smarter AUTonomous sensOrs' (MASAUTO) targeting Horizon Europe.

assistant: **Abstract**

MASAUTO is a research and training program for 10 early stage researchers (ESRs), focusing on developing a new generation ofmaterials that will overcome the current bottlenecks in the capability and capacity of autonomous sensors. The design of materials forremote sensing applications, such as real-time information on climate changes or for intelligent transportation systems, stillrepresents an enormous challenge. The ongoing exponential growth of the internet of things (IoT) ecosystem - which could reach atrillion devices in the near future - poses a serious challenge in terms of powering and interconnecting the underlying devices. The fullpotential of the IoT will only be achievable if devices i) have a reliable and sustainable autonomous power supply, and ii) are capableof processing information with reduced power requirements. A promising approach to address the first challenge is the use of anenergy harvester-supercapacitor combination, while for the second challenge a promising strategy is the use of non-volatile randomaccess memories. It's, therefore, crucial to develop materials for energy harvesting and storage, as well as low loss electronics.Through MASAUTO, we will create a highly trained cohort of scientists and technologists, enabling rapid and broadcommercialization and implementation of technology in public and private research centers and in industrial institutions. The ESRswill acquire a solid multidisciplinary scientific training, from basic science to industrial applications, which will enable them togenerate new scientific knowledge of the highest impact. MASAUTO will also deliver practical training on transferable skills in order toincrease employability prospects and to provide the researchers with access to highly skilled employment opportunities
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Innovative Hydrometallurgical Processes to recover Metals from WEEE including lamps and batteries' under Seventh Framework.

assistant: **Concept**

The recycling business is traditionally dominated by SMEs. In the last 2-3 years a general trend in the electronics recycling sector to bigger companies is very visible. Multinational, multisector companies are buying several smaller recyclers every year.  This trend is caused by 2 factors: • Many countries transposed the WEEE- and Battery Directives in a way relying heavily on collective systems.  • Also the big secondary raw material processors are more interested in few big contracts instead of a lot of small contracts as this brings down their administrative costs. Therefore it is close to impossible to sell materials with a high metal concentration for SMEs at the moment.  Therefore the HydroWEEE project deals with the recovery of base and precious metals from WEEE including lamps and spent batteries by hydrometallurgical processes. The idea is to develop a mobile plant using hydrometallurgical processes to extract metals like Copper (Cu), Manganese (Mn), Zinc (Zn), Yttrium (Y), Indium (In), … in a high purity (above 95%). By making this plant mobile (in a container) several SMEs can benefit from the same plant at different times and therefore limit the necessary quantities of waste as well as investments. In addition this new HydroWEEE process will produce pure enough materials that they can be directly used by end-users for electroplating. Because of this 2 levels of intermediaries from today (bigger recyclers and secondary material processors) will be bypassed. This will make the SMEs much more competitive than today and reverse the general trend to bigger companies.  The HydroWEEE consortium has 9 partners from 4 countries - 3 EU Member States (Austria, Romania, Italy) and a Western Balkan Country (Serbia).  All in all it has been calculated that HydroWEEE gene
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Harmonised and standardised procedures for evaluation of plant protection products, fertilizers and soil conditioners for use in organic agriculture' in the context of a Fifth Framework call.

assistant: **Objectives**

The objective of this Concerted Action is to develop recommendations for harmonized and standardised procedures for evaluation of Plant Protection Products (PPP) and Fertilizers and Soil Conditioners (F&SC) authorised for use in organic agriculture according to EEC 2092/91, Annex II to harmonise and improve the quality of organic products and to give organic farmers in Europe more equal. Competitive conditions. The project consists of 6 work packages (Was) with 5 workshops. WP1 is for coordination and project management. Inventories on implementation of Annex II and evaluation procedures in the participating countries representing North, West, South and Central Europe will be elaborated in WP2 (PPP) and WP3 (F&SC). Standardised procedures for evaluation of PPP and F&SC will be elaborated in WP4 & WP5. Recommendations on evaluation procedures for FPP and F&SC plus research needs and dissemination will be discussed in WP6.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Motor simulation: Evaluating the role of mirror neurons in humans through ECOG and Lesion Studies' to be submitted under Horizon 2020.

assistant: **Abstract**

One of the most intriguing, yet controversial findings in neuroscience in the past two decades is the discovery of the mirror neuron system (MNS). These visuo-motor neurons discharge both when a monkey does a particular goal-directed action and also when it observes another individual doing a similar action. The result of this mechanism is thought to be the capacity to recognize that an individual is performing an action, to differentiate this action from others analogous to it, and to use this information in order to act appropriately. This mechanism has been proposed as the basis for social cognition, and deficits in social understanding, such as those seen in autism spectrum disorder, have been linked to deficits in the MNS. Here I propose to use 2 novel approaches to address the neurobiological and behavioral significance of the human mirror neuron system (hMNS). (a) I will use Electrocorticography (ECoG) in neurosurgical patients to assess where, when, and how neurons in the prefrontal, parietal and sensorimotor regions are involved in action recognition. (b) I will employ scalp EEG and behavioral measures in a unique cohort of patients with damage centered in the Inferior Frontal Gyrus (IFG) or the Inferior Parietal Lobule (IPL). If the IFG and IPL are the core regions of the hMNS, patients with lesions to these regions should show deficits in understanding others’ actions, intentions and emotions (when these are expressed by body motion). This research will further our knowledge on the neural underpinnings of social understanding, and on the consequences of deficits in these neural networks.


**Keywords:** mirror neurons, motor simulation, understanding others, embodied cognition, EEG, lesion patients, ECoG
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Microscopic transformations in arable land and shell midden habitation in coastal Northern Europe during the 4th and 3rd Millennium BC'.

assistant: **Innovation**

The later fourth and third millennium BC in Northwest and Northeast Europe are a period characterised by important social changes, such as the migration of peoples, the emergence of new hierarchies, new ways of treating the dead, and intensifying exchange networks. At the same time this period often represents the final stage of a long-term economical process, the transition from a hunting, gathering and fishing economy to a primarily agricultural way of life. Several recent findings however show that this is not a one-way process, and especially in coastal regions a much more complex picture must be envisaged, even for this final stage of the Neolithic. Two kinds of archaeological phenomena, both often overlooked in scholarly debates, characterise this complexity: the (shell)midden and the arable field. Within MicroTRASH, these two phenomena are studied from a microscopic and a biochemical perspective. The scientific methods of micromorphology and lipid biomarkers enable a detailed disentangling of midden accumulation, shellfish consumption and arable land management (including manuring and irrigation practices) during this period. Additional use of absolute dating techniques and statistical modelling generate an increased temporal framework. This allows for a better understanding of subsistence practices, their temporality and the interplay between agriculture and shellfish gathering. In doing so, MicroTRASH is providing a better picture of coastal communities and their particular ways of life in Northwest and Northeast Europe amidst of the large-scale social and cultural transformations.


**Keywords:** Coastal archaeology, archaeological science, Neolithic, archaeological soil micromorphology, prehistoric subsistence