RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Ultrafast All-Electron Microscopy' (ULMI), addressing dissemination and exploitation.

assistant: **Impact**

Atoms and electrons are the central building blocks of almost all materials around us. Whenever there is a process or change, the atoms and the electrons have to move from initial to final configurations. These movements are very fast and very small: nanometers to picometers in space and femtoseconds to attoseconds in time. Ultrafast electron microscopy can provide a movie-like access, but we can only see processes that are excited by special laser light, although many reaction phenomena in nature proceed with a much less specific stimulus. This project has two major aims. (a) We will use sequences of ultrashort electron pulses to develop novel ways to understand ultrasmall and ultrafast material dynamics with nanometer/atomic control. (b) We will advance ultrafast spectroscopy and imaging towards a statistical investigation of reaction dynamics as they occur in unspecific ways. We will become capable of understanding reaction dynamics on atomic scales and obtain first-ever insight into femtosecond processes in so far unobservable regimes. Based on these new capabilities, we will investigate a broad range of questions in materials science, nanophotonics, electronic circuitry, magnetism, chemistry and atomic physics, in order to better understand and optimize the functionality of advanced materials for technology and life.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Sixth Framework proposal on 'COMPANIONS: persistent multi-modal interfaces to the Internet'.

assistant: **Innovation**

The COMPANIONS vision is that of a personalized, conversational interface to the Internet, one that knows its owner, on a range of platforms, indoor and nomadic, based on integrated high-quality research in multimodal human-computer interfaces, intelligent agents, and human language technology. This is a research agenda bound by a metaphor, that of the COMPANION, an artefact for the large groups of EU citizens whom the Internet simply does not serve as well as it does the academics who invented it. Among those groups are those who live alone: up to 40% of the population of advanced societies will live alone within 20 years, only half of them old. They will be in need of interactive company, conversation and diversion, over and above their need to use the Internet to get information or use chatrooms, or, increasingly, to make sense of their own digital repositories (texts, videos, images) as well as information held about themselves. These needs have not been well met by current interfaces based on browsing, profiling and adaptation, and there is good evidence that a more directly personal language-using persistent interface will be more acceptable. Our case in this proposal is that the technical basis for a Companion agent to the Internet is now in view: and what is needed is a fresh research effort to bring stronger methods of machine learning to bear on these three modalities and their integration. Within 4 years a new integration of existing and novel techniques can be achieved that will together provide a striking advance over anything currently demonstrable, and that enough can be shown after an eighteen month effort to attract the attention of major industrial players. The Consortium contains centres with outstanding world expertise in the application of Machine L
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Sixth Framework proposal on 'Aircraft external noise research Network and co-ordination'.

assistant: **Concept**

The X3-NOISE Coordination Action, through its network structure and comprehensive workplan involving experts groups, scientific workshops, stakeholders seminars and a common information system, will address the aircraft noise challenges set by the ACARE 20 20 Vision.To this end, it will more specifically:- Evaluate EC-funded projects results and assess their contribution to the state-of-the-art.- Formulate, through development of common strategies and complementarity with national activities, priorities and key topics for future projects aimed at noise reduction at source as well as improved understanding of the impact of aircraft noise in the community.- Identify potential reinforcement of future projects partnership through expertise mapping, to foster new collaborations and promote novel ideas.- Ensure dissemination and exploitation of anticipated technology breakthroughs and scientific developments, including technical information aimed at Regulatory Bodies and Policymaking Agencies to inform on progress made in aircraft noise research.- Contribute to an improved integration of the European Aircraft Noise Research Community through a network of National Focal Points, including the development of local networks in new EU member states to foster participation in future projects.The project scope is fully consistent with the FP6 workprogramme on Aeronautics and Space, significantly contributing to the objectives of reducing aircraft external noise by 4-5 dB and by 10 dB per operation in the short and long-term respectively. Over 4 years, the project will involve 28 partners from 17 countries (FR,UK,ES,NL,BE,DE,SE,IT,PL,HE,HU, CZ,LT,IE,PT,RO,CH). A genuine transnational approach has been elaborated to deal with Aircraft Noise Research issues, combining the complementary
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'MULTIPLATFORM FIELD SURVEILLANCE FOR INTEGRAL CROP HEALTH, EARLY DETECTION AND ACTUATION' (CERBERUS) under Horizon Europe.

assistant: **Objectives**

CERBERUS will capitalize on early detection to reduce pesticide use and on intelligent spray applications to sustainably eradicate pests at their early stages, when damage is reduced and the impact of treatments is high even with low spray rates. The project will combine large-scale crop observation models enhanced by the high revisiting time and diversity of bands offered by Copernicus, with the high reliability of proximal sensing granted by IoT insect traps reporting at a daily basis, robot-based monitoring at less than 1 m from the crops, and the granularity resulting from citizen data using dedicated apps. Data coming from multiple sources will be merged through a cloud platform, which will produce risk maps and spraying recommendations for users by applying AI algorithms. CERBERUS will be the outcome of a multi-actor approach by co-creating and sharing knowledge with all the different type of actors along the whole project. Cerberus will be validated for three quarantine pests (F. dorée, X. fastidiosa, B. dorsalis) and three commonly managed pests (L. botrana, B. oleae, C. capitata), and for the three most important specialty crops in the Mediterranean basin: wine-production vineyards, olive oil producing orchards, and citrus plantations. The multi-actor approach will be strengthened by the complementarity of the consortium: three academic partners, three technology companies, one citizen science specialist, a government agency involved in crop protection, and five end-users from Italy, Cyprus and Spain, providing two pilot plots per country and target crop. The proposed concept and methodology of CERBERUS has the potential to deploy an innovative crop surveillance system, enhanced by early detection in high-value crops to firmly step ahead in the effective applic
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Integrated Control, Process and Green Solvent Design for Biorefinery Process' (GreenSolProCon), addressing dissemination and exploitation.

assistant: **Impact**

This project proposes a comprehensive approach to design future biorefinery and biobased chemical plants by integrating green solvent, process, and control design. Green solvents, such as Ionic Liquids (ILs), Deep Eutectic Solvents (DESs), and biobased solvents, offer a sustainable alternative to conventional toxic solvents. Despite their potential, their application in chemical process plant design remains underexplored. This project aims to develop a holistic framework that addresses the unique properties of green solvents, focusing on mathematical modeling, solvent regeneration design, dynamic process analysis, control system design, and experimental validation. By advancing green chemistry practices, the project aspires to pave the way for sustainable, commercial-scale biorefinery plants, aligning with the goals of a circular economy and contributing to a green transformation of the chemical industry. The project will model solvent properties, optimize process efficiency, and ensure safe and sustainable chemical processes, ultimately setting a new standard for the biobased industry.


**Keywords:** Green solvents, Integrated design, Solvent regeneration, Biobased economy, Green chemistry, Sustainability
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Breeding for coffee and cocoa root resilience in low input farming systems based on improved rootstocks' (BOLERO).

assistant: **Innovation**

Fruit tree crops (FTC), represented by more than 50 species grown on over 100 M Ha, are strongly affected by climate change (CC). Thanks to grafting, rootstocks can confer enhanced tolerance to abiotic and biotic stresses, providing a valuable solution to expand food production. BOLERO aims to i) develop phenotyping tools, ii) employ them to score root system architecture (RSA) traits of coffee/cocoa, including grafted plants, under controlled and on-field conditions, iii) decode the microbiome of coffee/cocoa plants and the interface with the root exudates with large-scale metabolic modelling, and iv) use these resources to build predictive models of RSA traits in terms of genotypic data and microbiome composition and abundance to accelerate coffee/cocoa breeding. This data compendium will be used in combination with a data hub to survey the genetic diversity in FTCs and use it to dissect the genetic basis of RSA traits and their plasticity. BOLERO will propose fast and low-cost breeding strategies to create rootstocks, which will be tested in low-input coffee/cocoa farming systems. The agronomic performances and profitability of grafted plants will be assessed in Vietnam. BOLERO will rely on the knowledge of the large scientific community in Europe, the support of national institutes in tropical countries, and the expertise of industries to lead a multidisciplinary study for rootstocks selection with Coffee as a model, Cocoa as proof of concept, and propose tools and techniques transferable easily to all FTCs. BOLERO will develop and demonstrate for the first time at a large scale the open-source seeds initiative. BOLERO will therefore contribute to the Biodiversity and Farm to Fork Strategies, through significant impacts on the way FTCs are bred and on the use of ben
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Standards and Regulations for the Bio-based Industry' in the context of a Horizon 2020 call.

assistant: **Objectives**

This project will contribute at establishing a coherent, well-coordinated and favourable regulatory / standardization framework for supporting the development of a cutting edge bio-economy for Europe. More specifically, support to the standardization process for the concrete development of new value chains based on lignocellulosic feedstocks and biomass from forests, from agriculture and from organic waste will be provided. The main objective of the STAR4BBI project is promoting a level playing field for bio-based products. The focus of the project will be on finding practical ways to modify regulations in such a way that alternative wording, product specifications, and/or measuring methods will eliminate hurdles without compromising the initial objectives of the standard or regulation.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Studying Morphogenesis by building reaction-diffusion networks in gel bead arrays', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Living matter is characterized as operating far out of equilibrium, and most of the cellular non-equilibrium processes are organized in extremely complex networks. A visible demonstration of some networks is morphogenesis, which is the driving force for the formation of patterns in tissue. In this project I aim to systematically study the underlying physical and chemical components of morphogenesis in an artificial system. The main characteristics are coupling of chemical reaction and diffusion times, spatial inhomogeneities and positive or negative feedback loops. To achieve this goal, I will assemble an array of prototype ‘cells’ consisting of monodisperse microscopic gel beads produced using microfluidic devices. Within these gel beads, enzymatic reactions will take place to mimic intracellular signaling processes, while the product of the enzymatic reactions can diffuse from one bead to another, thereby resembling cell-cell communication. The enzymatic reactions chosen for my project are self-catalyzed proteolysis and kinase self-phosphorylation, both of which will generate positive feedback. A negative feedback loop will be introduced by using the peptidase cascade by hydrolysis of a pre-inhibitor, releasing a free inhibitor after cleavage.An analysis of the reaction diffusion profile is a novel method for measuring enzyme kinetics. As a spin-off from this project, I am interested to use a reaction-diffusion between two drops for the study of interaction of enzyme with inhibitors, in order to miniaturize and accelerate an inhibitor screening.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Harnessing an energy-expending, appetite-suppressing fat-brain axis to unlock novel pharmacotherapies' (HEAT-UP).

assistant: **Innovation**

Obesity and cardiometabolic diseases are global crises that threaten to cripple healthcare infrastructures. These disorders originate from an excess calorie burden caused by consuming too much food and expending too little energy. Yet despite recent advances in obesity drugs, weight-lowering pharmacotherapies only reach about half the efficacy of surgical interventions. This difference could be due to existing drugs only acting to reduce food intake and not boost calorie-burning. Therefore, I believe our discovery of a leptin-independent signaling axis between adipose tissue (AT) and the central nervous system (CNS) that both decreases food intake and increases energy expenditure poses a breakthrough in obesity research. We uncovered this axis through receptor profiling and human genetic association studies and engineered a highly selective agonist that significantly decreases bodyweight and improves glucose and lipid homeostasis in obese mice. Our preliminary data have already led to a spinout company. However, the physiological signaling mechanisms of this receptor in AT and the CNS that shape systemic energy balance through peripheral calorie-burning and central control of food intake remain unknown. Thus, in HEAT-UP, we will delineate AT and CNS receptor circuits with single cell resolution and functionally test this signaling in 3D cultures of mouse and human AT. Tissue-specific contributions to whole-body metabolism will be assessed by combining our proprietary, selective agonist with state-of-the-art viral, genetic, and surgical manipulation of the receptor and neuronal wiring in AT and the CNS. Viral and genetic cell-labeling strategies will be used to characterize novel secretory cells that we found in mouse and human AT to contain the ligand for this receptor.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Dissecting the interaction network of the histone demethylase LSD1 in vivo' under Seventh Framework.

assistant: **Concept**

Each cell within an organism contains the same genetic information, however, only a specific subset of genes is transcribed in a given cell at a given time. This cell/stage specific transcription is controlled by the coordinated action of signaling pathways, chromatin associated proteins and transcription factors. Defects in chromatin organization and gene expression due to aberrant activity of chromatin modifying enzymes can contribute to diseases such as cancer. Since its discovery, the histone demethylase LSD1 has emerged as a key chromatin regulator. Several studies have implicated LSD1 in tumorigenesis and there is a growing interest in its use as a drug target. However, we still have a limited knowledge of LSD1 pathway-specific functions and a genome-wide study of its role in a whole organism is lacking.My strategy is to use an animal model system, Drosophila melanogaster, to dissect LSD1 function in vivo. My work has shown that mutation of LSD1 Drosophila ortholog, dLsd1 impacts specific developmental processes. Taking advantage of the tools available in Drosophila, I discovered a surprising antagonism between the histone H3K4 demethylases dLsd1 and Lid at chromatin boundaries and an involvement of dLsd1 in the Notch signaling, which we found to be conserved in mammals. To identify novel pathways involving dLsd1 in vivo, my lab is carrying out a genome-wide RNAi screen in Drosophila. We plan to study how dLsd1 and key candidates discovered in the screen control gene transcription and chromatin homeostasis in specific developmental contexts. We then plan to take a few new key interactions and to test whether this newly acquired information is conserved in mammals and can be exploited to target tumor cells. The goal is to provide insights into the LSD1 network of i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Knowledge and information transfer system' under Fifth Framework.

assistant: **Concept**

The main objective of KITS is to increase the effective use of advanced Ecommerce technologies and methodologies by SMEs involved, at different stages, in value chain relationships. The project will address this through two lines of activity:1. Researching and analysing the current use of Ecommerce technology by SMEs engaged in value chain relationships, their role(s) and economic relationships in extended value chains and between SMEs in dynamic networks;2. Identifying such SMEs and bringing them into a Community of Interest (COI) spanning four regional clusters. The COI will concentrate on benchmarking the SMEs? use of E-commerce technology and developing strategies to enable them to progress to more advanced technology, so that they can reap greater business benefit.OBJECTIVESThe main objective of KITS is to increase the effective use of advanced Ecommerce technologies and methodologies by SMEs involved, at different stages, in value chain relationships It will thus:1) Acquire an understanding of the current economic position of SMEs in value chain relationships, the organisational and technological requirements for SME participation in value chains today, and as new types of value chain evolve;2) Track how this position and these needs change over time as SMEs leverage advanced E-commerce technology;3) Encourage and support SMEs in the uptake of the required technology through a Community of Interest (COI) and to Benchmark the Ecommerce activities of the SMEs of the COI against the research findings of Ecommerce of SMEs in supply chain relationships;4)Publish the results to help SMEs adopt advanced Ecommerce technology.DESCRIPTION OF WORKThe project will achieve its objectives through two lines of activity:1. Researching and analysing the current use of Ecommerce te