RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'New chitosan formulations for the prevention and treatment of diseases and dysfunctions of the digestive tract (Hypercholesterolemia, overweight, ulcerative colitis and celiac disease (CHITOSANPEROS)' (CHITOSANPEROS).

assistant: **Concept**

At present, chitosan tablets are commercially available as over-the-counter dietary supplements for hypercholesterolemia and overweight Nevertheless, their formulation is primitive because the chitosan used is not in the most suitable physical and biochemi cal form. Thus the consumers are forced to take large daily doses, and face exceedingly high costs and poor results. Moreover for celiac disease, no dietary food incorporating chitosan exists. This kind of patients have to use expensive gluten-free dietary foods instead of bread and pasta, with economical, nutritional and psychological distress: all these inconveniences could be removed by a proper incorporation of chitosan. Finally it is likely (but not yet investigated) that colitis patients might have be nefits from chitosan intake, should chitosan be developed into a carrier for colitis-specific drugs. This proposal intends to develop new chitosan physical forms and formulations useful for the prevention and treatment of said widely occurring diseases an d dysfunctions of the digestive system, that eventually develop into serious chronic diseases (hart diseases, obesity, diabetes, malabsorption, Crohn disease) that constitute heavy social burdens. The rationale is that chitosan has to be put into amorphous form, increasing its surface area, porosity, solubility and compressibility: in this way tabletting becomes feasible without the use of binders and higher efficacy is obtained; moreover, the total weight of a tablet is much lower. This will be achieved by spray-drying, freeze-drying and other techniques available in the food industry, involving most recent advances in the chemistry of alkaline chitosan solutions. Assessments will include instrumental analytical chemistry, biochemistry, microbiology and org anole
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Reduced GREENhouse gas emissions and sustainable wastewater treatment by integrated Control and Operational STrategies' (GREENCOST) under Seventh Framework.

assistant: **Objectives**

In order to ensure the supply of quality water for human consumption, irrigation and industrial operations, the number of wastewater treatment plants (WWTP) is expected to increase, simultaneously becoming ever more complex. One of the negative impacts that would involve the proliferation of WWTP is the emission of greenhouse gases, responsible for global warming. The main scientific objective of this project is to produce a generic methodology to design a control structure intended to reduce the emissions of greenhouse gases from wastewater treatment.  To demonstrate the methodology, an advanced control system aimed at low greenhouse gases emission will be instrumented in a novel and complex WWTP pilot plant at the hosting group featuring an anaerobic stage, an aerobic/anoxic stage and a filtration stage. To achieve the reduction of greenhouse gas emissions and the control of the plant, the use of incomplete knowledge and models will be considered in the control system. The success of the methodology and control system will be evaluated on the operation of the pilot plant.The reduction of greenhouse gas emissions will be also tackled with an operational approach as a secondary objective.  Guidelines and alternatives to run anaerobic-aerobic systems will be explored, in order to improve their efficiency and reducing GHG emissions.This project has also been planned with objectives to enhance the applicant’s career integration. It will serve to complete his training on process control with the practical set-up of a control system and to specialise in an important field as the control and modelling of bioreactors/WWTP. Transversal skills will also be cultivated with responsibility on student supervision, project management and cooperation with the industrial sector helping
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Unmasking cellular and molecular networks encoding risk and resilience in Alzheimer’s disease' to be submitted under Horizon 2020.

assistant: **Abstract**

AlzheimerAlzheimer’s disease (AD) is a crucial problem in our society, raising the need for new therapeutic targets. Evidence suggests multiple non-neuronal cells are implicated in the systemic deficits of AD, but the complex cellular diversity in the brain hampers the investigation of specific cells and their interactions. Moreover, the course of the disease is highly variable, due to multiple risk factors, including aging and gender, which have overlapping molecular signatures with AD that might be further masking disease mechanisms.I propose to expand the resolution from tissues to cellular environments, and to untangle overlapping molecular signatures of gender and aging, in order to unmask molecular mechanism of AD. Technological advances in genomics and imaging, including the single nucleus RNA-sequencing methods developed by me, as well as my expertise in computational analysis and CRIPSR perturbations, provide a unique opportunity to address this challenge. I obtained preliminary results strongly suggesting that multiple cell types are indeed altered in AD brains of mice and humans, and that gender, aging, and AD have overlapping molecular features. I hypothesize that age-dependent cellular/molecular alterations are key drivers of cognitive decline, and that the dynamics of these alterations determine risk and resilience levels in individuals.   We will test this hypothesis by: 1) Charting the cellular microenvironments and tissue topology of the human AD brain, to reveal cells, pathways, and cellular interactions driving AD; 2) Mapping the dynamic cellular/molecular trajectories in aging and AD in w.t. and AD mice, to untangle AD, aging, and gender dimorphism; and 3) Identifying regulators of cognitive resilience and decline in AD and aging, and connecting gene
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Store Logistics and Payment with NFC' (StoLPaN) targeting Sixth Framework.

assistant: **Abstract**

The StoLPaN project intends to turn NFC enabled mobile handsets into multifunction terminals with bi-directional interaction between the NFC chip and wireless communication channels and to demonstrate the use of this generally applicable new technology in mobile micro payment transactions and in the retail logistical value chain.A general host environment will be developed that will enable NFC enabled mobile handsets to run various business applications making use of the NFC interface. Smart tag technology will be used to let the EPC tags be captured with NFC enabled, networked devices, where NFC will form a secure bi-directional bridge between the local networks and the mobile communication channels. Secure management of the NFC chip is realized by the extension of existing and development of new APIs, standards. The new technical architecture will be deployed into devices like smart shopping carts, smart security gates and payment terminals.The new developments will be used to provide a secure, transparent environment in NFC enabled mobile handsets, where the handset's resources will be used for managing the various functions of the NFC chip, enabling it for operating as a secure payment purse and host of multiple business instruments. Through the new technology secure, operator independent remote management of the NFC chip will be possible over wireless channels. The described technology developments will be demonstrated in a retail environment, where customers will be able to make purchases, pay and check-out using the NFC enabled smart devices without any check-out counters, greatly reducing shopping time and increasing store capacity. Besides technical research and development the project work includes research activity related to security, legal, privacy and cons
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Enabling Robot and assisted living environment for Independent Care and Health Monitoring of the Elderly'.

assistant: **Concept**

ENRICHME tackles the progressive decline of cognitive capacity in the ageing population proposing an integrated platform for Ambient Assisted Living (AAL) with a mobile service robot for long-term human monitoring and interaction, which helps the elderly to remain independent and active for longer. The system will contribute and build on recent advances in mobile service robotics and AAL, exploiting new non-invasive techniques for physiological and activity monitoring, as well as adaptive Human-Robot Interaction (HRI), to provide services in support to mental fitness and social inclusion. The system will enable caregivers and medical staff to identify evolving trends of cognitive impairments and to detect immediate emergencies. ENRICHME will use new qualitative models for rich yet compact representations of daily life activities. It will also identify humans in order to provide personalized services for elderly living with other persons. Novel context-aware HRI will provide tools for cognitive stimulation and social inclusion, which improve over time by learning from and adapting to the state of the user. A professional infrastructure of networked care will widen the social sphere of intervention in support of elderly and caregivers. ENRICHME includes multi-disciplinary research in geriatrics, gerontology and gero-technology, enabling further studies in social sciences and neuropsychology. Thanks to a modular implementation, which limits costs and allows for maximal flexibility, the system will be tested in 2 separate AAL labs and validated for 1 year in 3 different elderly housing facilities across Europe. Significant impact is expected by prolonging the independent living at home of elderly who need constant monitoring. Their quality of life will be improved by dedica
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Greening the Poles: Science, the Environment, and the Creation of the Modern Arctic and Antarctic' (GRETPOL).

assistant: **Innovation**

This project investigates how and why environmental concerns have become so important to our conceptions of the polar regions today. Through a historical study of both the Arctic and Antarctic from 1945 to the turn of the past century, the project explores the connections between how environments are described - particularly through the natural sciences and economics - and the judgments made about how those environments should be administered. The key hypothesis of this project is that the process of describing an environment cannot be separated from the process of controlling and managing it. Changing perceptions of concepts such as  development, ecological fragility, and wilderness have provided frames for describing and understanding the polar regions. Why has natural resource extraction been deemed appropriate (or even necessary) in some contexts, and wholly forbidden in others? Why did the concept of sustainable development become important during the 1980s? Can we think of scientific research programs as instruments of colonialism? And why did national parks and conservation agreements become politically useful? GRETPOL will produce a new understanding of how far from being the passive frames for human action, environments (in the polar regions but indeed also beyond) are constructed by human agency. As anthropogenic climate change reduces polar ice extent and threatens the entire globe, the question has never been timelier.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'The origin of mitochondria and the root of the eukaryotic tree' (MITEUKROOT).

assistant: **Concept**

The origins of eukaryotes and mitochondria are among the most fundamental questions in biology and are central to understanding eukaryotic genomic and cellular evolution. It is now accepted that the mitochondrion was ancestrally present in all eukaryotic groups and that it derives from an alpha-proteobacterium, although the precise identity of the original endosymbiont is unknown. In this project the candidate will use sophisticated computational analyses to investigate current hypotheses for the origin of eukaryotes, to identify the closest alpha-proteobacterial relatives of mitochondria, and to determine the root of the eukaryotic tree. Genome-wide computational analysis tools developed by the host lab will be used to identify genes transferred from the mitochondrial endosymbiont to the eukaryotic host nuclear genome during the evolution of the mitochondrion. The cohort of transferred genes will then be used to (i) determine the position of mitochondria among contemporary alpha-proteobacteria and (ii) root the eukaryotic tree.  To do this, the candidate will be trained in the most sophisticated probabilistic methods for modeling sequence evolution and for inferring evolutionary relationships.  The project is multidisciplinary and will enhance the candidate's analytical, mathematical and computational skills on a series of tightly focused biological problems for which the host laboratory has a strong international reputation.  These new skills, and her already extensive international experience and contacts, will provide her with the competencies to develop a leading role as a European evolutionary biologist and bioinformatician. The project will also provide her with generic analytical skills relevant to the FP7 Health theme, ""Multidisciplinary fundamental genomics a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Control of Campylobacter infection in broiler flocks through two-steps strategy: nutrition and vaccination' under Seventh Framework.

assistant: **Concept**

Campylobacteriosis is the most frequently reported zoonotic illness at the EU in 2011, with 9 million human cases, and a total annual cost of 2.4 billion € per year in the EU27. Poultry meat is the major single source of human infection. Recent studies have shown that European broiler flocks have a high prevalence of Campylobacter colonization with an average of 71%. However, there is still no effective, reliable and practical strategy available to prevent or to reduce Campylobacter colonization in broilers. The objective of the present project is to develop a two-steps strategy in order to fight against Campylobacter in primary poultry production: first step nutritional approach, through the use of a synergic combination of different products such as plant extracts (PE), organic acids (OA), prebiotics (PRE), probiotics (PRO), and feed presentation (FP) through 4 work packages (WPs) in which trials with infected broilers and in experimental and real conditions will be done. In a second step, vaccination approach based on a novel development of a Campylobacter vaccine through the use of reverse vaccinology. The expected results of the project will be a short term strategy through new nutritional strategies based on a synergic combination of feed products and feed presentation and a medium term strategy through a novel vaccine to reduce the prevalence of Campylobacter in broiler flocks.The consortium is formed by five National poultry producers SME-AGs (PROPOLLO, FIA, CIDEF, NEPLUVI and BTT), two RTD (ANSES, and IMASDE) and three SMEs (MIKROLAB, REDONDO, and CZV).
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Erwin Schroedinger Fellowships', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

With this proposal the FWF applies for COFUND of the Erwin Schrödinger Programm the largest Outgoing-Program in Austria for basic research at postdoc level open to all disciplines and destinations.  According to the objectives of the COFUND-action the programm aims to support researchers to work abroad at leading research institutions and on leading research programmes to open up new areas of knowledge, new scientific approaches, methods and techniques. In this way it helps the fellows broadening and deepening their competence and establishing long lasting international cooperations. The very high impact on career development of the Schrödinger fellows has been shown in the program evaluation. By improving the program with the possibilty to apply also for a reintegration-phase, the FWF wants to facilitate the critical return phase for the fellows and on a long turn counter the brain drain from Austria and consequently from the ERA.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Economic and Technological Intelligence for SMEs in Non-Nuclear Energy sector' under Fifth Framework.

assistant: **Concept**

The main objective of the ETINNE project is to support the development of competitiveness and innovation potential of small and medium sized enterprises in the field of non-nuclear energy. A wide range of activities will follow this objective for SMEs implemented by 8 partners from Austria, Cyprus, Czech Republic, Denmark, Great Britain, Hungary, Latvia and Slovak Republic. Within the ETINNE project the SMEs suitable for technological co-operation and collaborative or co-operative projects will be identified, analysed, trained and assisted. Furthermore special activities focused on innovation promotion and building of project consortia will be introduced.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Triggering Mechanisms of Snow Slab Avalanches'.

assistant: **Concept**

Snow avalanche is the most frequent type of slope failure in mountainous areas of the world. In total, approximately 15% of Europe’s and 6% of Earth’s land may be considered as avalanche prone-areas. Avalanches claim hundreds of lives annually worldwide and there have been historical cases with death tolls between hundreds and thousands of people during one event or winter season.One of the main goals of snow avalanche research is to forecast natural or induced mechanical failure of a sloping layered snowpack in order to estimate potential damage to human activities in mountain regions and to be able to conduct risk-oriented planning. The deadliest type of snow avalanches are slab avalanches, which start from a failure of a cohesive horizon of snow, or “slab”, underlaid by a so called “weak layer”. The nature of weak layer deformation is considered the crux of slab stability. At present, the origin of initial failure and the failure process in the weak layer remain poorly understood.In order to contribute to development of a mechanical model of snow fracture, and to provide tools to estimate initial conditions for avalanche dynamic models for hazard mapping and risk management, we propose to investigate the mechanical behavior of weak layers and their relationship to slope-scale instability.Key objectives of the study are: 1) To design instrumental apparatus for both cold laboratory and in situ field work to study the mechanical behavior of snow weak layers. 2) To obtain, through experiment, fully operational mechanical laws of different types of alpine snow weak layers. 3) To critically review existing modeling approaches for weak layer and slab in order to couple best existing practices with experimentally obtained results. 4) To relate the micro and meso-scale weak l