RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Representational Mechanisms of Neural Location Encoding of Real-life Sounds in Normal and Hearing Impaired Listeners.' (SOLOC), addressing dissemination and exploitation.

assistant: **Impact**

With the rise of urbanization, silence has become a rarity. Sound is all around us, and our hearing skills are essential in everyday life. Spatial hearing is one of these skills: We use sound localization to determine where something is happening in our surroundings, or to ‘zoom in’ on a friend’s voice and filter out the noise background in the bar. But how does the brain compute the location of real-life, complex sounds such as a voice? Knowledge of these neural computational mechanisms is crucial to develop remedies for when spatial hearing fails, such as in hearing loss (>34 million EU citizens). Hearing impaired (HI) listeners experience great difficulties with understanding speech in everyday, noisy environments despite the use of an assistive hearing device like a cochlear implant (CI). Their difficulties are partially caused by reduced spatial hearing, which hampers filtering out a specific sound such as a voice based on its position. The resulting communication problems impact personal wellbeing as well as the economy (e.g. higher unemployment rates). In SOLOC, I use an innovative, intersectional approach combining cutting-edge computational modelling (deep neural networks) with state-of-the-art neuroscience and clinical audiology to gain insight into the brain mechanisms underpinning sound localization. Using this knowledge, I explore signal processing strategies for CIs that boost spatial encoding in the brain to improve speech-in-noise understanding. Through this Global Fellowship, I connect the unique computational expertise of Prof. Mesgarani (Columbia University) and his experience with translating computational neuroscience into clinical applications, to the exceptional medical expertise on hearing loss and CIs of Prof. Kremer (Maastricht University). Hen
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'CHALLENGES AND INNOVATIVE CHANGES IN RESEARCH ETHICS REVIEWS' (CHANGER), addressing dissemination and exploitation.

assistant: **Impact**

Trust in science and technology as well as the utility and acceptability of their innovative outcomes is crucially dependent on the ethical qualities of the research. This is the reason why research projects are submitted to an ethical review. Although the existing ethics review infrastructure includes experienced members with expertise in traditional research, this is not the case for new technologies and transformative research that result in new human rights, such as digital rights. Thus, there is a clear need for ethics committees to evolve in order to cover this gap and to be able to support innovation while embedding new human rights. CHANGER aims to promote changes in research ethics reviews that strengthen the capacities of researchers to incorporate ethical judgements in the project design and implementation, and to support ethics committees to address new challenges posed by new technologies and new research practices. CHANGER will review current practices and ethics criteria, will identify and discuss new challenges emerging from new technologies and from new research practices, which are not sufficiently covered in the current review process, will provide innovative training to ethics review experts and researchers, and propose innovative approaches and tools to ethics review reform and new understandings to practice ethics by design, supported by guidelines and a policy roadmap. The CHANGER interdisciplinary consortium has extensive and long-standing experience-based expertise in research ethics reviews, integrity oversight and human rights and is capable of providing novel solutions to the needs in ethics reviews.


**Keywords:** ethics, ethics review, research ethics committees, ethics by design, new technologies, AI, gene editing, organoids, electronic c
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'European network of DNA, cell and tissue banks on rare diseases' will create measurable scientific, societal and economic impact aligned with Fifth Framework.

assistant: **Impact**

Eurobiobank will set up the first operating network of rare diseases biological resources centres in Europe, gathering and facilitating the access to nearly 150.000 existing human biological samples of DNA, tissues and cell cultures. The network gathers 16 partners from 8 countries and is open to new memberships. It will optimise the exploitation of biological collections of human material. It will help reaching a critical mass of collections indispensable for research on rare diseases. Activities will focus on: development of a dedicated website interconnecting and facilitating access to collections; definition of high quality criteria and Standard Operating Procedures; mapping of relevant practical ethical issues; dissemination of SOP and know-how to the whole European scientific community, particularly through a training programme and information activities.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Symmetry of the superconducting order parameter in tetragonal, single layer high tc compounds - growth of single crystals and angularly resolved tunneling studies' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

Recent evidence was found for d-wave symmetry of the superconducting order parame- ter in YBC0. This sets serious theoretical constraints in understanding high Tc superconductivity. A basic question is whether d-wave symmetry is induced from the double CuO2 layer structure of YBC0. Investigation of the superconducting symmetry in other compounds containing a single layer of CuO2 is thus crucial. We propose angularly resolved tunneling studies in single crystals of Hg-1201, Bi-2201 and Tl-1201. All these compounds have a single CuO2 layer and moreover their structure is tetragonal, as opposed to the orthorhombic structure of YBC0. This simplifies much the interpretation of the data. We propose several routes for the growth of single crystals. Tunneling measurements will be done in the Centre de Recherches sur les Trhs Basses Tempiratures in the CNRS in Grenoble. Structural studies will be pursued in collaboration with the Laboratoire de Cristallographie in Grenoble, using conventional and synchrotron X-ray diffraction as well as neutron diffraction.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Sixth Framework proposal on 'Combined study of nanostructured magnetic materials'.

assistant: **Concept**

The Laboratory of Magnetism from University of BiaBlystok (Poland) has started to change its scientific program from investigation of thin films (mainly garnets) to study of magnetic nanostructures - a highly innovative research filed with high potential f or future expansion in science and technology.NANOMAG-LAB-supported transformation of our research program will be focused on the development of experimental techniques connected with:- magnetooptical both milimagnetometry and micromagnetometry (based on optical microscopy) for wide range of magnetic field pulse amplitude, orientation, and duration; temperature, light wavelength, light path configuration (enabling magnetization vector position analysis),...- scanning probe microscopy, mainly AFM, MFM and STM. New theoretical approaches, supported by numerical simulations and verified by experiment, will be developed for deeper understanding of structural, magnetic (statics and dynamics of magnetization distribution), optical and magneto-optical properties of ultra-thin systems.Correlation between these properties and the structure of those nanosized objects on the level of atomic scale will be analysed. Digital image processing techniques will be developed for both magnetic and structural images. Planned ex-situ research will correlate to sample preparation and in-situ characterization.Nanostructured ferromagnets (mainly) with artificial three-dimensional patterning will be prepared in collaboration with different laboratories from Polish Network - Magnetism in low dimensional structures- and from NANOMAG-LAB partners.Transfer of knowledge of experimental techniques, which are not expected to be developed in BiaBlystok in the nearest future, is intended, especially related to sample growth and complex characterization
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'European bioinformatics early-stage training in advanced research' (BIOSTAR), addressing dissemination and exploitation.

assistant: **Impact**

The publication of the human genome sequence, along with that of other organisms, has created an unprecedented demand for bioinformatics tools to allow researchers to mine and analyse the explosion of data, which continues to emerge. More sophisticated too ls also require more sophisticated skills from the people who use them, and the shortage of skilled bioinformaticians needs to be addressed for Europe to remain competitive in the field. The European Bioinformatics Institute (EBI) will make its resources a nd expertise available to provide this training. The EBI hosts five core European molecular biology databases and over 160 other tools and resources, providing state-of-the-art services to allow biologists to analyse large data sets, as well as a thriving and diverse research base. Training is already a major activity at the EBI, but as the demand for training in bioinformatics far exceeds the supply, the training of European early-stage researchers will be expanded through the current EST Training Site gra nt.The training fellowships are intended to give PhD students (or equivalent) from all over Europe the opportunity to gain skills in bioinformatics through short (3 ¿ 6 months) fellowships at the EBI. The students will work as part of one of the research and development teams at EBI, and the main part of the training will be in the form of a research project, closely supervised by the group leader. The training courses, workshops and seminars on offer, both at the EBI and the other institutes at the Wellc ome Trust Genome Campus, will form part of the training. The training will be open to students in any relevant field and participants will include both trainee bioinformaticians, who will receive more specialised training, and, for example, biologists and bioche
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Bringing a modular technology for fresh water sea-transportation to full scale', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

XXL-REFRESH is built upon the results obtained by the REFRESH project (GA 262494), in which the project team demonstrated the feasibility of transportation of large quantities of fresh water by the sea using modular flexible barges. The key innovation introduced by REFRESH is the use of open modular textile containers connected by extra-strong watertight zips and the use of an online monitoring system for the control of the container deformations during service using wireless communication system.REFRESH culminated at the beginning of November 2012 with the successful transportation trial of 200 cubic metres freshwater payload with a 16 nautical miles sea voyage in the gulf of Souda, Crete. The next steps required to bring the innovation into the market comprise the manufacturing of a full-scale waterbag with a payload of 2.000 cubic metres and the conduction of demonstration voyages at different locations within Europe and outside. Technical activities covered by XXL-REFRESH include the design optimisation of the full-scale waterbag, implementing what learned during the trials in Crete, and the scaling up of the manufacturing processes for the manufacturing of one full-scale waterbag. Demonstration trials are included in the programme at two different locations in the Mediterranean Sea and outside, since the need for cost efficient and reliable technologies for fresh water transportation is global. Dissemination and exploitation activities are also included.The consortium includes five partners from the former REFRESH project complemented by two new partners in charge of confectioning the full-scale waterbag and performing the water transport service.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Molecular characterisation of a clinical model of estrogen receptor-positive breast cancer dormancy'.

assistant: **Concept**

Endocrine therapy has clearly improved outcomes for estrogen receptor alpha positive (ER+) breast cancer patients, however the cumulative incidence of recurrence and death continues at a steady rate . The majority of ER+ breast tumours treated with neoadjuvant letrozole in respond quickly and are generally excised after three months. A minority of tumours maintain a stable size by becoming dormant, these tumours continue to receive extended letrozole treatment and therefore represent the best currently available clinical model to investigate dormancy. We have previously performed a number of dynamic molecular studies of cancer treatment by taking pre- and post-treatment tumour biopsies utilising the ""window of opportunity"". In this study, for the first time, the dormant cancer cells from breast tumour biopsies that have received extended (1-3 years) neoadjuvant endocrine therapy will be studied. This study aims to characterise the ER+ breast cancer dormancy and letrozole resistance using expression profiling technologies of this unique series of breast tumour biopsies. The genome- and proteome-wide expression data will be analysed and compared with data for the same patients at diagnosis, at two weeks and at three months following treatment and with the clinical outcomes. Our study will be the first to characterise extended growth suppression in letrozole-treated dormant-state breast cancer. This knowledge will be very valuable to extend ER+ breast cancer patients' survival and quality of life by preventing metastasis and also contribute to the economy and society by introducing a individualized therapy that is tailored in accordance with cancer patients’ expression profiles. This multidisciplinary project combines both clinical and academic aspects along with exposur
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Mechanical ignition hazards in potentially explosive gas and dust atmospheres' goes beyond current state-of-the-art under Fifth Framework.

assistant: **Innovation**

Mechanical ignition sources are important under the ATEX Directive, but little is known of the risk associated with them. Characteristics of sparks and hot spots produced by impact, friction and grinding are to be measured. Simulated ignition sources with the same characteristics will be used to measure the sensitivity of explosive environments to ignition and this sensitivity will be characterized in relation to standard measurements of the ignitability of the explosive substances. The results of the two parts of the experimental programme will be combined to categorize equipment intended for use in potentially explosive environments on the basis of the type of mechanical ignition sources likely to arise from a specific design and method of operation and the environments likely to be ignited by these sources. A proposal for a methodology for inclusion in European Standards on preparing Ignition Hazard Assessments will be produced.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'The moral foundations of activism' (TMFOA).

assistant: **Concept**

The proposed project will address the role of moral conviction in collective action: i.e. cooperative effort toward social change such as the Occupy movement and the Arab spring. Existing theory and research indicates that strong, long term commitment to social change results from a politicization process wherein individuals come to identify with a social movement and internalize its norms and values, resulting in action on its behalf. We argue that this politicization process results in the formation of a moral conviction about the goal of collective action, and 1) that this moral conviction is responsible for the effects of politicization on collective action readiness, but also that it has the potential 2) to sour the relation between activists and non-activists and to lower activists’ ability to attract followers, and 3) to lead to the dehumanization of political opponents and to justify the use of aggressive forms of collective action. Building on his established expertise, the Fellowship enables Dr. Zaal to provide a novel perspective on engagement in collective action, and to offer new insights in the mobilization and radicalization processes that are vital to understanding social change but have received little attention in the collective action literature. The proposed project provides the ideal opportunity for Dr. Zaal to achieve these research objectives and to develop a position of professional maturity. During the project, Dr. Zaal will benefit greatly from regular face-to-face meetings with Professor Barreto, an internationally renowned expert on social change, and from the training he will receive from her on social identity, social influence, morality and dehumanization. In addition, Dr. Zaal will benefit from being embedded in the Social, Environmental
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Collaborative Virtual ENvironments' in the context of a Fourth Framework call.

assistant: **Objectives**

COVEN aims at developing a computational service for teleworking and virtual presence. The overall objective of the project is to provide the facilities needed to support future cooperative teleworking systems and to demonstrate the added value of networked VR for both professional users and home users.COVEN is developing a general platform for Collaborative Virtual Environments (CVEs), providing the application-level services needed to support the implementation of these CVEs. The development of the COVEN platform is driven by the needs of two CVE applications addressing professional and home users.The general result of the project will be a comprehensive understanding of the different issues and requirements in the design and realisation of shared virtual environments, at the different network, distribution, runtime services and application levels, in both professional and citizen contexts. Foreseen achievements specifically include:A set of runtime services supporting the realisation of CVE applications, integrated within a networked VR platform; a set of techniques specifically addressing scalability at services as well as distribution architecture levels.Two CVE application demonstrators, in both home user and professional contexts.A model of network traffic requirements for these kinds of applications.A human factors evaluation of the usability and added value of this technology.Active contributions to the DIS, VRML and MPEG4-SNHC standardisation processes.A first cycle of development was recently completed, with first versions of the COVEN applications, services and platform now available, together with first results regarding networking requirements; this work is disseminated through a set of papers, public reports and video (check our web site, http://chinon.th