RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Aggregate and Idiosyncratic Risk in Macroeconomics' (AIRMAC).

assistant: **Concept**

Since the Great Recession of 08/09, two interrelated economic phenomena challenge politics and research alike. First, the return of aggregate volatility marking the end of the Great Moderation. Second, the rise in inequality to levels last seen during the Gilded Age. A new literature has responded to this challenge by adding heterogeneity to business cycle models (HANK). This is a major step, but the focus on certainty-equivalent solutions in aggregates restricts the interaction of both phenomena. My research agenda aims to make ground-breaking progress by developing a new computational toolbox that allows to study the relative strength of aggregate and idiosyncratic risks and their interaction in inequality, asset returns, and business cycles.Part I develops a sparse higher-order perturbation solution for HANK models. Smart use of the modularity of idiosyncratic and aggregate model components makes estimation feasible, which is key for quantification.Part II measures heterogeneity in the exposure to aggregate risk and quantifies its contribution inequality. The volatility of wages, portfolio returns, and tax rates differs across the distribution, and this affects inequality via household portfolio decisions. Part III decomposes the capital premium into the parts coming from idiosyncratic and aggregate risk. Large parts of the capital stock feature trading costs that can explain part of the equity premium, which makes the equity premium puzzle less severe.Part IV examines the cost of business cycles and novel benefits of stabilization policies. By reducing aggregate risk, policy allows households to hold less liquid portfolios and increase investment into capital.Part II-IV contribute to fundamental questions in macroeconomics: the welfare costs of business cycles, the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Improving indoor environments and health using cold negative air ionisation' under Fifth Framework.

assistant: **Concept**

The project will investigate cold negative air ionisation technology to improve an indoor environment in terms of particulates and volatile organic compounds. The novel technology has the potential to significantly reduce the numbers of coarse (non reparable) and fine (reparable) particulates, hence reducing the exposure of humans to these potential hazards to health. The problem with particulates isn't so much their physical size but the compounds absorbed onto their surfaces. Many of the compounds associated with reparable particulate matter are potentially hazardous to health. In terms of volatile organic compounds, the technology has the potential to change the chemistry of these, especially via oxidation. In contrast with conventional ionisers, no ozone is produced by the technology. The proposed research will involve controlled studies of a number of indoor environments with respect to the analysis of the environment as well as the health of its occupants.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Modulation of juvenile hormone signaling by receptor phosphorylation' (JHSIGNAL) under Horizon 2020.

assistant: **Objectives**

Juvenile hormones (JHs) are lipophilic signals of vital importance to insects and related arthropods, representing the most successful group of animals on our planet. Among species relying on regulation by JH are beneficial pollinators and crustaceans, as well as agricultural pests and disease vectors. Manipulation of JH signaling is a good target for insecticide control. Therefore, knowledge of JH signaling is important both for fundamental science and for practical use. The intracellular JH receptor has been identified, largely through work in the host laboratory, but its action is still poorly understood. Current evidence suggests that activity of this JH receptor is modulated by JH-induced phosphorylation. The objective of this proposal is to identify the phosphorylation target sites and to determine their significance for the JH receptor function. To achieve this goal, the status of amino acid residues potentially phosphorylated in response to JH will be determined using mass spectrometry of the JH receptor protein expressed in insect cell lines. The key residues will be mutated either to prevent phosphorylation or to mimic a constitutively phosphorylated state, and the mutant receptors will be examined for capacity to bind JH, induce JH-response genes, and sustain normal insect development in vivo. The approach thus ranges from protein biochemistry through cell-based assays to developmental genetics employing the Drosophila model. The goals are achievable through the combined expertise of the Applicant, extensively trained in protein chemistry and molecular biology at the top-ranking US universities, and the host laboratory of Dr. Marek Jindra, who is among the leaders in insect developmental endocrinology and JH research in particular. This project will enable th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Deusto International Research School' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

With a proven track in PhD training (more than 1000 PhD in 50 years, 58 in 2013) the Deusto International Research School (DIRS) aims at attracting qualified international Early Stage Researchers for high quality PhD training that enhance research, complementary and transferable skills.DIRS aims are grounded in a solid structure generated around a robust and dynamic ecosystem that encourages and enables cooperation, co-creation and collegiality among 7 doctoral programmes and 24 research groups around four research foci centred on challenges identified in the EU and the Basque Smart Specialisation Strategies: i) Health and Wellbeing, ii) Human Rights, Peace and Conflict Resolution, iii) Sustainable Development and Innovation and iv) Lifelong Learning. UDEUSTO has actively and creatively procured conditions conducive to frequent dialogues between economic, cultural and social actors whose cooperation and exchanges help realise DIRS aims. These dialogues will ensure international and intersectoral mobility, including placements/internships to broaden ESR career employability tracks; cross-fertilisation of ideas and ideation of solutions to societal challenges fuelled by shared concerns and funding. 40 partners formally back DIRS project.16 MSC PhD candidates will be selected via an open, transparent, merit-based, impartial, equitable and internationally advertised process that will take special care to avoid any form of discrimination. Upon acceptance, PhD candidates will sign an employment contract and will be hosted in an attractive environment to benefit from a shared supervision and mentoring process formally inscribed in the Doctoral Agreement and the individualized research/training development plan (Personal Career Development Plan). Full internationalisation is an
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Sniff-Controlled Devices' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

In our ERC project (OdorSpace), we uncovered the speed, accuracy, and robustness of human sniffing behavior. This led us to hypothesize that we could use sniffs as control-signals. We built a sniff-sensor, and used signals generated by sniffs to power external devices. We call this the sniff-controller. We found that healthy individuals could use the sniff-controller to actuate a computer with speed and accuracy similar to those of a mouse or joystick, and that completely paralyzed individuals could use the sniff-controller to communicate text, and even to drive an electric wheelchair. The sniff-controller has dramatically improved the lives of a small number of individuals who participated in our studies. These individuals, who previously had no means of communication, now surf the web and send us emails using the sniff-controller. That said, the current results were in the context of a scientific experiment where we have demonstrated that if highly qualified individuals spend significant time with a patient, they can implement the sniff-controller. But would a naïve user be able to use the device if they purchased it by mail? Can the device transform to be a “product”? Moreover, can the sniff-controller serve markets other than the disabled? These critical questions are first on the mind of anybody who would consider commercializing this invention. To answer these critical questions, the current proposal’s goals are: 1. To optimize the device. 2. To conduct a proof of concept pilot, consisting of a platform that allows individuals to order the device off the web, use it, and provide feedback on its use. Such a platform will provide a backbone for a company, which can either spin-off as a start-up, or be bought by an existing company. This project may transform the liv
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'In Vitro Reconstitution of the Minimal Eukaryotic Cell Cycle Oscillator' to be submitted under Horizon Europe.

assistant: **Abstract**

Cell growth and division are the basis of all forms of life. In eukaryotes, the clock-like cycles of genome duplication and cell division are orchestrated by a complex set of biochemical reactions. Theory suggests that a negative feedback loop regulating the cyclin-dependent kinase 1 generates the cell cycle oscillations; however, because the putative cell cycle ‘clock’ is tightly interlinked with numerous other biological networks, experimental validation has proven to be a challenge. To date, several questions key to understanding how cell cycle oscillations arise remain unanswered: Do the identified core components indeed give rise to oscillations? Which components are necessary and sufficient? And what makes the cell cycle clock oscillate with varying frequency? To unravel what makes the cell cycle ‘tick’, we will reconstitute the core cell cycle oscillator in vitro. Specifically, combining state-of-the-art biochemistry, including the powerful frog egg extract system, with synthetic and computational biology, we will (1) develop fluorescent-based sensors to monitor key enzymatic activities of the cell cycle oscillator,  (2) use computational models to identify operational conditions for the reconstitution of the oscillator, (3) reconstitute and analyse the individual reactions of the predicted negative feedback loop, and  (4) assemble the complete cell cycle oscillator in vitro and establish its capacity to oscillate, the set of necessary components, and which elements of the oscillator define its frequency. Using in vitro reconstitution as a radically new approach to interrogating the cell cycle, CellCycleInVitro will answer longstanding questions about the cell cycle clock. But more than this, in developing a novel in vitro experimental platform and biosensors for
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Migrants and Minorities in European Cities: The Interaction of Economic, Spatial and Social Factors in Generating Pathways to Social Exclusion' will create measurable scientific, societal and economic impact aligned with Fourth Framework.

assistant: **Impact**

This Thematic Network involves research teams from eight states of the European Union (five from Northem Europe, three from Southern Europe) in order to help testing a theoritical model fo the explanation of social exclusion as it affects some of the most vulnerable groups in European member states.The model proposes that social exclusion is a function of the interaction between: * The match between skills and opportunities for employment. * The physical access to those opportunities. * The social barriers to entry into employment. The argument is that social exclusion can be viewed as a product of what jobs are available, where they are located and how they are filled. These are considered as independent processes, but ones which interact in generating the balance of constraint and opportunity on which social exclusion ultimately depends. The thematic network aims at: * Idendifying forms of social exclusion and the pathways through which they are generated for migrants and minorities in different types of cities. * Assessing the effects of economic changes and national and city-level on generating pathways to social exclusion. * Considering the reasons for variation in the employment fortunes of different groups of migrants and ethnnic minorities when compared with the indigenous population. * Analysing the neighbourhood effects on social exclusion in different urban contexts when compared with household and individual sectors to build a repertoire of social indicators for both forms of social exclusion and for the pathways through which they are reached. Five state-of-the-art" meetings will be organised and will generate a comparative volume related to eight states of the European Union (five from Northern Europe, three from Southern Europe), on the following thems: 1
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Multimode scratch testing: Extension of operation modes and update of instruments' (1994-1998), addressing dissemination and exploitation.

assistant: **Impact**

Scratch testing under progressive loading (PLST) is a wide-spread engineering method for mechanical strength asessment (adhesive and cohesive strength!) of coated materials. So far the almost exclusive quality criteria retained are critical loads for cohesive and adhesive coating-failure (LCl, LC2) as directly detected off-line by scratch track inspection under a microscope and frequently on-line, indirectly, by means of abrupt variations in acoustic emission (AE) and/or friction force (FF). For practical friction and wear applications under cyclic (essentially elastic) loading, a major detrimental hard coating failure mechanism is brittleness, with mode I (through thickness) cracks, once generated, likely to propagate in mode II along the substrate/coating interface. For medium to high strength coatings (LCl, LC2 > 40N) quality ranking, based exclusively on critical loads of spalling, is often too severe and sometimes even misleading with respect to tribological field applications" The unambiguous assessment of first cracking failure is thus a key to scientifically backed up laboratory quality ranking with a good predictive potential as to surface mechanical field applications, and thus a prerequisite basis for efficient written standards. For both AE and FF there are sofar no instruments available allowing for online detection of minor cracking events The present work is meant to overcome this shortcoming by introducing high speed AE detection and video monitoring of the ontact zone in the stress applied state (because of closing up after unloading, small cracks will also pass undetected under the microscope). Thus the capabilities of the well known engineering scratch test can be considerably extended and upgraded. The objective of this project is to pave the way for
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Combinatorics, geometry, and computation', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

Marie-Curie-Scholarships for 3 Ph.D. students are available for a 3 to 12 month stay in Berlin. In connection with our European Graduate Program ' 'Combinatorics, Geometry, and Computation' ' we became a Marie Curie Training Site. We can support young researchers pursuing doctoral studies and providing them with the possibility of undertaking part of their doctoral studies in a country other than their own. Applicants must already have an advisor and a dissertation project in mathematics, computer science, or a related area at their home university. The Marie curie Training Site is a joint initiative of the three universities of Berlin - Free University, Technical University, Humboldt-University - and the Konrad-Zuse-Research Center. The amount of the scholarship is 1200,00 Euro per month. The scientific program ranges from theoretical fundamentals to applications. The areas of research are combinatorics, geometry, optimisation, algorithms and computation. During their stay the students are supervised by the professors Aigner, Alt, Rote, Schulz (FU), Möhring, Ziegler (TU), Prömel (HU) and Grötschel (ZIB). Applications with curriculum vitae, copies of certificates, publications, a letter of recommendation of the advisor and a brief description of the status of the dissertation project should be sent to: Prof. Dr. Helmut Alt Institut für Informatik Freie Universität BerlinTakustrasseD-14195 Berlin Further information can be obtained from: Bettina Felsner: phone ++49-30-838 75 104 e-mail: bfelsner@inf.fu-berlin.de
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Ecosystem loss of soil inorganic carbon with agricultural conversion: fate, rate, mechanisms, and pathways' to be submitted under Seventh Framework.

assistant: **Abstract**

The goal of this proposed research is to understand effects of agricultural conversions on soil inorganic carbon (SIC) cycle. Mitigating rising atmospheric CO2 is a top priority for human and environmental health. Despite their prevalence and increasing pressure from land-use changes, effect of SIC on climate regulation is thought to be insignificant in the short-term, leading to focused efforts and research on other means of carbon sequestration. The proposed research builds on the fellow’s previous NSF-funded project, in which large losses of SIC were observed with the land-use changes, and has potential to transform the current understanding of these issues. In this proposal, soil incubations in a factorial design will simulate land use-induced ecosystem changes (soil water flux, acidification, freeze-thaw cycle) to identify mechanisms of SIC transformations. Incubators customized for the field-observed conditions such as drainage, are used to approximate water-carbonate reactions closely, and periodic measurements of inorganic carbon in gas and water fluxes using stable isotopes will determine the potential rates and pathways of fluxes from SIC. Lab and field conditions will be simulated with coupled geochemistry and hydrology codes and the results compared to those from the lab and field to help improve our understanding of SIC processes. The proposal integrates geochemistry and hydrology with original methodologies involving field, lab, and modeled data for predictive understanding of rate, fate, and mechanisms of SIC transformations with land-use changes. The mentor (Dr. S. Trumbore) and the host institute (Max Planck Institute of Biogeochemistry in Jena, Germany) collectively bring expertise in isotopes and biogeochemical modeling, demonstrate excellent research
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Applied venomics of the cone snail species Conus consors for the accelerated, cheaper, safer and more ethical production of innovative biomedical drugs' (CONCO).

assistant: **Concept**

Venomous animals represent a major source of highly selective and efficient bioactive compounds that have already led to the development of several new drugs. The latest FDA approved example is Prialt, a peptide originating from the venom of a cone snail (Conus magus). CONCO is an innovative post-genomic project dedicated to the discovery and development of novel biopharmaceuticals generated by the broad biodiversity of cone snails.The project aims at characterizing from the genomic up to potential therapeutic properties all the putative bioactive compounds that can be synthesised by a cone snail species. The genome and transcriptome of Conus consors will be exhaustively studied. Large amounts of venom will be fractionated and submitted to proteomic studies to generate a biochemically characterized 'natural library' of compounds. Large-scale synthesis of each identified candidate will be achieved to form a synthetic library" of compounds."