RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Correlative Super Resolution and Real-Time Imaging of Herpes Virus Infection', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Fluorescence imaging is a powerful technique that has transformed our understanding of biology. Recently, a number of techniques have been developed that overcome one of the fundamental limitations of fluorescence imaging, namely the diffraction limit.  With these techniques, it is now possible to resolve sub-cellular architecture in multiple colors and 3D with unprecedented detail. However, the main limitation of these techniques has been the slow acquisition times making it difficult to study dynamic processes. Since biological samples are inherently highly dynamic, this limitation is a major hurdle that needs to be overcome. I will develop a correlative fluorescence imaging technique that combines the capabilities of super resolution and real-time imaging.  With this correlative technique it will be possible to observe the dynamics of a biological sample in real-time and subsequently “freeze” the dynamics (by fixation or low temperature) at a time of interest to obtain a super resolution image. The dynamics can therefore be correlated with ultrastructural information, combining the capabilities of real-time and super resolution imaging.  I will apply this correlative imaging technique to study infection mechanism of Herpes Simplex Virus (HSV). HSV is a medically important virus that infects neurons and epithelial cells. Besides the health hazards that it poses, HSV also has important implications in gene therapy. However, the details of HSV infection mechanism remain poorly understood. Since HSV infection involves dynamic interactions between virus particles and sub-cellular components, both of which are tens of nanometers in length scale, this is an ideal model system in which the correlative super resolution and real-time imaging technique will lead to important in
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Compact, light, efficient and reliable turbo compressor for fuel cell vehicles' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

The stronger regulation of carbon dioxide emissions, rising consumer awareness towards eco-friendly energy sources, and the need to minimize our dependency on fossil fuels are boosting the fuel cell electric vehicle (FCEV) market. Fuel cells need to be fed with a constant supply of oxygen, usually from air provided by a compressor. While much attention has been put on the fuel cell itself and the hydrogen storage, the oxygen supply has not been yet optimized. Currently, air management for fuel cell systems remains a challenge because today’s compressor technologies are not optimized for fuel cell applications.  We are CELEROTON, a Swiss high-tech business at the forefront of high-speed turbo compressor technology. We are able to achieve speeds up to 280,000 rpm, which allows our product to be 20 times lighter and smaller than state-of-the-art compressors, while achieving the highest efficiency of all commercial compressors. Moreover, our compressor is 100% oil-free which results in the highest air purity, crucial to increase the fuel cell lifetime. Since our foundation in 2008, we have invested over 1.6M€ to develop our compressor technology up to near-commercial stage. Now, with project TURBO-FUELCELL, we aim to take the last technical and commercial steps to introduce our unique turbo compressor as the key technology for oxygen supply in the fuel cell vehicle market. This market with such growth potential (predicted to increase at 22.1% CAGR up to 2024 reaching 1.2 B€), could greatly benefit from the compactness and lightness of our product.  Our vision is contributing to the deployment of fuel cell vehicles in Europe, increasing their efficiency and decreasing their cost thanks to our compact, lightweight, quiet and reliable air compressor. We aim to achieve sales of
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'European fisheries ecosystem plan' goes beyond current state-of-the-art under Fifth Framework.

assistant: **Innovation**

The ultimate aim of this work is to develop a framework for the implementation of 'Fisheries Ecosystem Plans' in Europe. This will be achieved through the involvement of marine scientists, social scientists, economists and the stakeholders (fishers and fisheries managers). We take the North Sea as a case study but also specifically include a consideration of the additional issues/regional differences that would influence development of such plans for the northern/sub-Arctic and Atlantic margin fisheries. The US National Marine Fisheries Service (NMFS, 1999) in a report to congress developed the concept of Fisheries Ecosystem Plans (FEP's).The actions to be taken in developing an FEP are designed to incorporate the principles and policies of ecosystem conservation into fisheries management. Specifically FEP's provide a description and understanding of the basic environmental and human context in which a fishery is managed, they direct the use of that information for fisheries management and define strategies.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Dietary lipids as risk factors in development. mechanistic issues.' (DLARFID) targeting Fifth Framework.

assistant: **Abstract**

Beta-carotene, the source of the lipid soluble Vita and retinue acid in humans was recommended for the prevention of arteriosclerosis and cancer development. Unexpectedly , the recent three multimembers, randomised human trials revealed the weak protective effect against the increased incidence of myocardial infarction, and morbidity/mortality due to the lung cancer. Since the b-carotene is commonly used as the food colorant , the influence of its metabolites together with fatty acids (FA) derivatives (known regulators of nuclear receptors) will be investigated in the healthy and cancer human and animal cells. The possible involvement of the new classes of proteins and genes (gene clusters) will be followed by the most modern methods to determine the early markers of pathology which would serve as the new diagnostic measure for the cancer hazard determination and understanding of the food and consumer safety.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Tuning the Tracks: Resolving the interplay between microtubule lattice conformation and kinesin-1 selectivity using cryo-EM', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Kinesin-1 transports cellular cargos along microtubules as part of neuronal transport. The localisation of kinesin-1 in neurons is tightly controlled to ensure the coordinated delivery of specific cargoes to the regions where they are required. One mechanism of control is through microtubule regulation, but the details of this are not well understood. It has recently been shown that microtubule lattice spacing influences kinesin-1 localisation in U2OS cells. However, the role lattice spacing plays in neuronal transport is unclear. This project aims to investigate features of kinesin-1 based neuronal transport on multiple scales. First, this project aims to use cryo-electron microscopy (cryo-EM) to elucidate how kinesin-1 binds to specific microtubule subsets. I will resolve the high-resolution cryo-EM structure of a dimeric kinesin-1 construct (stableMARK) bound to microtubules with different lattice states. This will explain its lattice specificity and help uncover the mechanics of kinesin-1 walking. Secondly, I will map microtubule lattice spacing in neurons using in situ cryo-electron tomography to establish the lattice diversity within this complex microtubule network. Thirdly, I will use cryo-correlative light electron microscopy and stableMARK to determine if lattice spacing influences kinesin-1 localisation in neurons. This project will answer key biological questions on cytoskeletal transport, which will be applicable to other microtubule-based motors and microtubule associated proteins. Defects in kinesin-1 based transport have been implicated in multiple neuropathies, such as Alzheimer’s disease, therefore further understanding of how neuronal transport is controlled will help uncover the mechanism of these diseases.


**Keywords:** cytoskeleton, kinesin, micr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'BotsAndUs - First Assistant Robot for Retail, Hospitality, Aiports and Real Estate Buildings'.

assistant: **Innovation**

Bad customer service leads to losses of over £37Bn for companies in the UK and $87Bn in the US alone each year. The companies from retail, hospitality, airports and real estate-buildings, which are our four key business verticals, are facing issues of understaffing, lack of insights and in-store inconsistencies, leading to a high degree of customer unsatisfaction. Therefore, there is an urgent need of introducing new technologies to boost customer service quality and sales. BotsAndUs created Bo, a robot easy-to-use, able to autonomously approach and engage in conversation, reacting to emotions, with the best Human-Robot-Interaction features. This innovative breakthrough technology combines social sciences, human-centred design and cutting-edge engineering. The robot is unique, complex and superior to all other product on the market, leading to a cut of 70% of losses caused by bad customer service, yet at an affordable price. Bo was tested and presented to various international events and companies and there is currently a demand of over 1,000 units to be deployed immediately. Bo has been proven to work in prototype trials (TRL6), raising high interest from customers, receiving orders of about €300K. Our potential clients are from Europe, Middle East and USA. The technology is highly scalable and can be deployed easily within existing distribution systems. During Phase 2, BotsAndUs will develop a fully working demonstrator (WP2), install a production infrastructure (WP3), carry out full-scale trials with pilot partners (WP4) and prepare the business plan and commercialization strategy (WP5). BotsAndUs targets the global serviceable market currently worth about €5Bn annually, which thanks to technological advances is likely to explode. The goal is to reach a turnover of o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Global Optimization of integrated PhotoVoltaics system for low electricity cost' in the context of a Horizon 2020 call.

assistant: **Objectives**

Scenarios have forecasted a long lasting amplification with PV electricity becoming the cheapest electricity source in many regions with costs in the range of 4 to 6 c€/kWh for EU by 2024, while 2.2 c€/kWh has been achieved for a 800 MW PV plant planned in Abu Dhabi for 2019.The PV market will continue to expand in the coming years with more than a doubling in the production capacity expected for 2024. At the same time investment in production capacities is foreseen to keep growing hence maintaining the sector highly competitive. For the European PV industry, which is struggling to survive after years of massive investments in China and south-east Asia, the growth of the market represents a chance to come back as a prime player on high-efficiency premium technologies. This is the positioning of GOPV to develop highly competitive technologies for the PV utility market and strong synergies between European players. The project will accelerate reduction of electricity cost implementing advanced PV features and creating synergies across 5 topic areas: Light Management; Energy Efficiency; Material Efficiency; System Reliability; and System configuration and O&M. Ultimately, it will set up an integrated 250 kW PV system to demonstrate a competitive electricity cost of 0.02 €/kWh for irradiation levels of 1900 kWh/m²/year GHI in Southern Europe. The levelised cost of electricity (LCOE) will hence be reduced by 50% (currently 0,04 €/kWh) and the energy payback time reduced by 40%, both in respect to actual standard solution and to PERC best in class mono-facial solution. GOPV project will deliver a 35 years lifetime for the PV string instead of 25 years standards.Beyond GOPV, the global turnover for the six industrial partners exploiting the results of the project will be close
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Ultra-High Field Magnetic Resonance Imaging'.

assistant: **Innovation**

The High field Magnetic Resonance (HiMR) Initial Training Network aims to train the future leaders of academic and industrial research in the fundamental science and novel applications of ultra-high field (UHF) in vivo magnetic resonance (MR), in order to address an increasing and currently unmet demand from academia and industry for such specialists. The highly complex and multi-faceted nature of UHF MR means that excellent training can only be provided by immersing ESRs in an environment that integrates different research areas, sectors and groups. The HiMR ITN is centred on a cutting edge, multidisciplinary research program that exploits the complementarities of the participants. This research programme is organised into four themes each focused on a crucial area of development of UHF. The first focuses on improved structural imaging, advancing our understanding of the origins of contrast in MRI scans and developing non-invasive biomarkers for multiple sclerosis. The second theme is centred upon exploiting UHF to develop ultra-high resolution functional MRI (fMRI) which will be very important in basic neuroscience research. It also aims to make fMRI more quantitative, thus encouraging its uptake in the clinic. The third theme aims to exploit the enhanced sensitivity of MR spectroscopy (MRS) at UHF in developing highly specific biomarkers. The final theme will develop novel hardware for both research and in the clinic, and methods of monitoring and correcting motion which limits in-vivo MR resolution. Finally the HiMR ITN will provide a unique opportunity to measure safety outcomes over a large group of workers. The proposed interdisciplinary and intersectoral training program, embedded in this research program, will provide a platform for training ESRs to become spec
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Energetic strategies of birds during reproduction' will create measurable scientific, societal and economic impact aligned with Fourth Framework.

assistant: **Impact**

Energetic strategies are of adaptative significance to living organisms that allow them to cope with high energetic expenditure. Energetic strategies for reproduction allow birds to optimize both their reproductive success and survival. New information about energetic strategies improves our understanding of the 'life-history strategies' of birds. In recent years, measurement of energy expenditure of free-ranging animals is made possible by using a non-invasive isotopic method. The ecological characteristics of reproduction in the Tengmalm's owl are well known, and this species therefore presents an ideal model for studies of energy expenditure. The major objective of this project is to determine the factors (clutch size, territory quality, food availability) that lead to a high energetic expenditure during the period of reproduction and the energetic strategy used. For this, the daily energetic expenditure and the energetic time-budget during the reproduction period will be evaluated.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Integrated Catalytic Recycling of Plastic Residues Into Added-Value Chemicals' (2014-2020).

assistant: **Concept**

Approximately 70% of European plastic waste (18.5 mt/year) is not being recycled due to technical or economic reasons and are thus sent to landfill (27%) or incinerated (42%). This situation affects negatively the environment in terms of pollution and greenhouse gases emissions, as well as social perception regarding waste management, consumer’s products industry and policy makers.iCAREPLAST addresses the cost and energy-efficient recycling of a large fraction of today’s non-recyclable plastics and composites from urban waste. Heterogeneous plastic mixtures will be converted into valuable chemicals (alkylaromatic) via chemical routes comprising sequential catalytic and separation steps. This multistage process will also yield carbon char and a pure CO2 stream as products, whilst it will present improved economic sustainability, operational flexibility and lower CO2 footprint thanks to (i) the energetic valorisation of gas by-products through innovative oxycombustion units integrated with efficient heat recovery; and (ii) the use of AI predictive control and real time optimisation. iCAREPLAST aims to demonstrate (TRL-7) the whole technology for plastic waste valorisation in a pilot plant able to process >100 kg/h of plastic. Advanced upstream waste sorting, pre-treatment and pyrolysis is strongly backed by previous demonstration activities and knowhow of the consortium, with profound knowledge of waste management and recycling market.iCAREPLAST solution will enforce circular economy by substantially increasing the amount of recycled plastics to produce commodity products that can be used for virgin-quality polymers production or as raw materials for other processes in petrochemicals, fine chemicals, automotive and detergent/surfactants industries. As a result of its init
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Development of a new production process to manufacture ultra-light buildingmaterials' under Fourth Framework.

assistant: **Concept**

The prime proposer is in the process of establishing a completely new to special sofware development. of stone, glue and light (aluminum)structure and are primarily used as facades. Special features are : - very light weight - shockresistent - more efficient use of natural resources - higher isolation values These products decrease the building costs per m2 for facades up to 100%. Not only because of the above mentioned features, but also because of the easy-to-install anchor system. The present goal is the development, introduction and optimisation of an on line computer integrated (CIME) production facility for manufacturing the existing ideas round ultralight systems, but also to introduce very fast all new building systems in the European market that are the result of common R&D-activities of the participants. The most important R&D-issues vary from chemical qualities (glue), knowledge of nature stone, mechanical engineering up to special sofware development.