RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Role and control of starter lysis in cheese production and ripening' demonstrating excellence, impact and implementation quality for a Fourth Framework call.

assistant: **Abstract**

Starter cultures play a crucial role in the fermentation of food products. Not only do they efficiently convert fermentable sugars in food materials, but in the same time they are responsible for a rapid decrease of the ambient ph. Both activities result in efficient protection against growth of undesirable microorganisms in the fermented product. An additional function of the starter organisms is generation of flavour compounds. These are produced, either as by-products during the sugar fermentation (i.e. Diacetyl, acetaldehyde) or as a result of the more gradual protein breakdown. This last process involves a variety of starter enzymes that are located almost exclusively in the cytoplasm of the starter bacteria. Since the activity of these enzymes is generally low, the whole proteolytic breakdown leading to flavour production is a very time-consuming operation. During this time, the starter bacteria will quickly exhaust their energy reserves and the precursors for flavour, peptides and amino acids, are not actively accumulated by the cells anymore. Flavour development can, theoretically, only proceed if the precursors can diffuse into the cells or, by far more likely, when the intracellular enzymes are released by Iysis of the starter bacteria. So, actual flavour development during ripening in fermented dairy products such as cheese can only occur as a result of lysis of the lactic acid bacteria. This project will determine the exact incidence and role of starter Iysis in several popular European cheese production processes. Furthermore, by increasing the incidence of starter lysis, accelerated ripening and improved flavour development will be two of the major achievements of this project.  This project aims to get complete control of the starter Iysis process by obta
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Understanding seabird distribution patterns to design marine Important Bird Areas (IBAs)' (IBAs).

assistant: **Innovation**

Marine Protected Areas (MPAs) are considered as a promising management tool under an Ecosystem-Based Management (EBM) approach. However, less than 1% of the oceans' surface is currently protected, and most MPAs are small and restricted to coastal areas, thus overlooking wide-ranging marine organisms which are key components of marine trophic webs (top predators) and useful monitoring tools of the anthropogenic impacts on the marine environment. Among these organisms, seabirds are conspicuous and provide an opportunity to study the influence of diverse variables (oceanographic, topographical, anthropogenic) to ultimately build predictive models helping to design and managing pelagic MPAs.MARIBA will run in coordination with a LIFE project directed to design Important Bird Areas at sea (marine IBAs) in Spain, a first interdisciplinary step to create MPAs accounting for wide-ranging marine organisms. Within the study area, highly threatened seabirds such as the critically endangered Balearic shearwater Puffinus mauretanicus require fast conservation action to understand and reduce their threats at sea, and this project is addressed in this way. MARIBA will take advantage of the data available from this LIFE project (remote sensing, surveys at sea) to ascertain which are the main factors influencing seabird distribution, and ultimately to develop predictive models to properly design the marine IBAs.A novel semi-experimental part of the project will compare seabird distribution between two fishing regimes (trawling moratoria vs. trawlers operating), to ascertain how trawling fisheries influence seabird distribution and, thus, how these activities should be regulated within the IBAs. Also novel for the region will be the consideration of food-availability descriptors at diffe
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Identification of Sclerotinia sclerotiorum Effector Proteins mediating virulence on Arabidopsis thaliana ecotypes' (SEPARATE) targeting Seventh Framework.

assistant: **Abstract**

Sclerotinia sclerotiorum is a necrotrophic fungus notorious for its broad host range, including notably oilseed rape, sunflower, lettuce, carrot, onion and potato. In most cases there is no variety with significant resistance or tolerance known to date. Small secreted proteins and low molecular weight metabolites have been reported in several necrotrophic fungi as critical for virulence. However, the role of these effector proteins in S. sclerotiorum virulence is largely unknown, and the molecular mechanisms by which S. sclerotiorum promotes host susceptibility remain poorly understood. We recently discovered that susceptibility to S. sclerotiorum is highly variable among A. thaliana accessions and our preliminary analyses on S. sclerotiorum genome sequence identified promising effector candidates. The objective of this proposal is to validate the function of S. sclerotiorum effector candidates in altering plant cells to promote susceptibility. We will (i) document the diversity of S. sclerotiorum effector protein candidates; (ii) identify effector candidates that promote susceptibility to S. sclerotiorum and (iii) identify effector candidates required for S. sclerotiorum virulence. This project will have a significant impact on our understanding of plant-microbe interactions by providing insights into key molecular processes regulating susceptibility to a necrotrophic pathogen. Besides, it will open new perspectives toward the development of tolerant crop varieties.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fifth Framework proposal on 'European Chronicles on-Line'.

assistant: **Innovation**

The ECHO participating Institutions have unique collections of documentary films dating from the beginning of the century until the sixties. These collections are very precious since they document different aspects (social, cultural, political, economic) of life in four European countries during this period of time. The aim of the project is to develop a long-term reusable software infrastructure providing Web-based access to its film collection, and to set up and run an ECHO digital library service. The project will integrate state-of-the-art existing technologies, such as the informedia technology (developed by Carnegie Mellon University) and the media-archive technology (developed by Tecmath), and will extend them to support new advanced services (semi-automatic metadata extraction and acquisition, integration of non-English speech recognizers for the purpose of indexing, searching and retrieval, cross-language retrieval capabilities, automatic film summary creation, privacy and billing systems). The ECHO participating Institutions have unique collections of documentary films dating from the beginning of the century until the sixties. These collections are very precious since they document different aspects (social, cultural, political, economic) of life in four European countries during this period of time. The aim of the project is to develop a long-term reusable software infrastructure providing Web-based access to its film collection, and to set up and run an ECHO digital library service. The project will integrate state-of-the-art existing technologies, such as the informedia technology (developed by Carnegie Mellon University) and the media-archive technology (developed by Tecmath), and will extend them to support new advanced services (semi-automatic metadata
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Highly innovative push-pull handbike for boosting wheelchair mobility' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

According to the United Nations Convention on the Rights of Persons with Disabilities (UNCRPD) to ensure effective personal mobility, wheelchair users need a wheelchair which fits them correctly and meets their specific needs. This requires an approach that is responsive to individual needs. However, statistics show that less than 5% of those in need have access to a properly fitted wheelchair. As the ‘traditional’ wheelchairs usually offer only a limited mobility and/or less healthy movements for their users, different connectable bicycles have been invented, but mainly with the traditional chain drive that can be operated by hand pedalling movements. We find the chain drive an outdated solution and the pedalling motion less healthy than the rowing moves, therefore we created a push-pull handbike with our highly innovative string drive technology, which can better meet the above cited requirements concerning wheelchair users’ mobility. With our future developments we aim to adjust our push-pull handbike to all segments of wheelchair users including women, children, the elderly and those who can use only one arm. After fully meeting all users’ needs, we plan to bring the handbike into serial production. For resultful developments - to be done preferably in a Phase 2 project - and a successful commercialisation, we would like to carry out the proposed Phase 1 project.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Microbiological fluorescence observatory for antibiotic resistance tracking'.

assistant: **Objectives**

The accurate quantification of microbial populations is critical for understanding how microbes evolve and adapt to stressful environments. This, in turn, can help improve rationales for drug deployment aimed at minimising the evolution of antibiotic resistance. Working on ERC-funded research into how microbial communities optimise their virulence traits and mediate drug-resistance, our team identified a need for a low cost photometry device capable of high-throughput quantification of microbial phenotypes such as microbial growth rates and metabolic efficiencies; microbial dose responses and susceptibility to antibiotics; antibiotic interactions datasets; microbial individuality and heterogeneity data and population mean gene expression profiles for fluorescently labeled genes. There are multiple positive consequences of having these capabilities at low cost: we can create high-throughput data pipelines for microbiology research, particularly for evolutionary studies or phenotypic screens; we can improve the dissemination of high-quality phenotypic data analysis algorithms (such as synergy tests for antibiotics) and so provide standardisation for those phenotypic assays; schools can benefit from the low-costs laboratory hardware and bring data analysis for microbiology into their mathematics, biology or computer science teaching; our lightweight devices with small footprints can be used to access geographically hard-to-reach areas where drug resistance phenotyping could be conducted using either battery or solar power. We are, therefore, now in the process of creating two prototypes that can perform these functions and we are seeking funding to finalise their design and field test the devices in three different settings: a partner research laboratory studying microbial
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'NutrImmune: Nutrient-controlled molecular pathways instructing development and function of mucosa-associated innate lymphocytes' to be submitted under Seventh Framework.

assistant: **Abstract**

The last decade has witnessed an explosion of research into the molecular networks ensuring maintenance of a mutualistic relationship between microbes and host cell networks at mucosal surfaces. Failure of such homeostatic or adaptive programs lead to susceptibility to intestinal infections or to chronic inflammation causing debilitating human diseases such as inflammatory bowel diseases or inflammation-induced intestinal cancer. In contrast to the role of the microbiota and its composition, the role of nutrients for development and function of the intestinal immune system has been a matter of speculation owing to the fact that molecular sensors of dietary molecules were widely unknown. Given the broad impact of nutrients on metabolic diseases and human health, research into the question of how the power of nutrients can be harnessed for improving human health and for the prevention of disease is much warranted. We have recently found that the aryl hydrocarbon receptor (AhR) is required for the development and function of an innate lymphocyte subset (RORγt+ ILC) that protects against intestinal infections and inflammatory bowel disease (Kiss, Science 2011). AhR serves as a ligand-inducible transcription factor sensing plant-derived phytochemicals and directly controls expression of genes required for the maintenance of RORγt+ ILC. The data established the first molecular link between diets and the development of immune system components. Here, we will test our central hypotheses that (1) diets adapt the function of the intestinal immune system by controlling the pool size of innate lymphocytes, and that (2) RORγt+ ILC directly control epithelial homeostasis and adaptation by regulating niche programs that control intestinal stem cell population dynamics. These aims link
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Improving the services of the NMP NCP Network through Trans-national Activities 2'.

assistant: **Concept**

The NMP TeAm 2 project aims at assisting the NMP NCP Network to provide good quality and high standard services to the proposers and therefore helping simplify access to FP7 calls, lowering the entry barriers for newcomers, and raising the average quality of submitted proposals. To this effect the four main objectives of this project are to optimise the tools at hand to the benefit of the networks clients, such as the partner search system developed in NMP TeAm, the use and further development of the NMP NCP Network website and other communication tools, to maximise the impact and add value to organised European wide events by organising parallel partnership building events, joint NMP NCP stands and joint awareness campaigns, to standardise the Network skills and provided services through the creation of documentation to aid the work of the NCPs and the actualization of the charter of services, staff exchanges, twinnings and targeted trainings and to forge and utilize the links with NMP related Networks, Technology platforms, the Enterprise Europe Network and the International collaboration programme.This project builds on the results and the achievements of the FP7 NMP NCP Network project NMP TeAm funded under NMP-2008-4.0-11 - NCP trans-national activities in April 2009 including the further improvement of the partner search tool and the interactive website, the training activities, the partnership building and other networking events and the cooperation with the NMP related Networks. New modules for training activities will be introduced to assist NCPs target specific sub-groups of the NMP clientele, namely SMEs, RTOs as well as international partners. Importance will be based on strengthening the ties within the Network, an essential ingredient for stronger and more
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Geologically Enhanced NaturE-based Solutions for climate change resiliency of critical water InfraStructure', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Groundwater represents the largest (and often the only practical) freshwater resource on oceanic islands. Due to the small area of many islands the amount of freshwater is limited, and it is particularly influenced by dynamic processes, including climate change. In the islands of Macaronesia any changes in climate conditions can have more severe negative effects on the available freshwater volume than in a continental environment, therefore, the protection of critical water infrastructure is of the highest priorities. The primary objective of GENESIS is to demonstrate that innovative, nature-based intelligent solutions for enhancing the climate resilience of critical water infrastructure can lead to more reliable and consistent/predictable water management practice by effectively protecting groundwater, by drastically improve the efficiency of water use and reuse, thus sustain social and economic activities while mitigating the potentially severe effects of climate change on local communities. The general concept of GENESIS is testing and showcasing local and regional NbS and delivering a deep demonstrator in the Macaronesian biogeographical area with the long term objective to provide climate-proof critical water infrastructure replicable for other islands and vulnerable zones of the EU mainland. The methodology is designed to provide the full workflow for implementing and demonstrating in operational environments how to capture, storage and protect water in an effective-strategic way (from diverse sources including storm runoff, treated wastewater and irrigation return flows) to mitigate the impacts of extreme events (droughts, floods, wildfires) and how to create climate resilient areas/islands. The development and implementation of systemic nature-based solutions fo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Revolutionizing Indoor Energy: The Emergence of Low-Cost Eco-Friendly, High-Efficiency Kesterite Solar Cells' in the context of a Horizon Europe call.

assistant: **Objectives**

Indoor Indoor photovoltaic (IPV) cells have the potential to power distributed and remote sensors, actuators, and communication devices enabling the widespread implementation of Internet of Things. Commercial (CIGS, CdTe) and emerging (Perovskite, organic solar cells) photovoltaic technologies face several challenges for indoor applications including cost, toxicity, and stability. In contrast, kesterite materials are composed of earth-abundant, non-toxic elements and show excellent stability. This technology has recently achieved efficiencies of 14.9% under AM1.5G, demonstrating its high efficiency potential. However, its current deployment for IPV is limited by low efficiency due to the spectral mismatch with the indoor spectrum, consequence of its low bandgap (1.1 eV).This proposal aims to develop efficient kesterite solar cells with a higher bandgap tailored for IPV applications. This project will combine advanced numerical simulations with an eco-friendly DMSO process and innovative precursor ink design, novel thermal annealing, and tailored electron selective contacts which will lead to significant improvements in the device performance.  The main objectives include: 1) To develop an advanced numerical model for kesterite solar cells, laying the theoretical foundation for device architecture design; 2) To design a compositionally flexible precursor ink that leads to sustainable and cost-efficient kesterite absorbers with flexible Eg (from 1.4 to 1.7 eV); 3) To synthesize high-quality kesterite films with using high-pressure thermal annealing; and 4) To deposit band-aligned electron selective contact materials for the various Eg kesterite. The project will lead to an impressive 25% efficiency for indoor kesterite solar cells and demonstrate efficient mini-modules. T