RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'A Single Cell AnaLysis and Sorting Platform based on Lensfree digital imaging techniques applied to Rapid Detection of Cancer' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Metastasis is responsible for > 90% of cancer-related deaths. Billions of dollars have been spent trying to cure primary tumors but very little was spent in trying to detect or kill the highly aggressive tumor cells that cause disease spreading.  One of the reasons is that single cell studies of rare cells in blood still present a large challenge.  Single cell analysis remains tedious with many different instruments and protocols, typically taking a few days of hands-on work.  This slows down research, but also hinders the translation to application in future clinical practice.  In SCALPEL, we envisage a high-content, high-throughput cell imaging and sorting platform, more compact and easier to use than any existing single cell analyzer.   The high content results from lensfree digital imaging of single cells on a high speed CMOS active optical pixel matrix to analyze the morphology of cells.  The high throughput results from a highly parallelized fluidic matrix that steers cells at high speed over the CMOS imaging blocks.  Lensfree cell sorters can be realized in a cheap and compact platform, as all optomechanical components (lenses, detectors, nozzles,...) are replaced by nanoelectronics, advanced imaging and signal processing technology.SCALPEL aims to perform a full feasibility study of this concept and will require to investigate the ultimate limits in:  1) maximizing image resolution and sensitivity to single cell morphological features obtained via lensfree holographic imaging; 2) maximizing cell manipulation speed in microfluidic systems via a high degree of parallelization; and 3) digital image signal processing with extremely low latency at reasonable power consumption. If this multidisciplinary complexity can be understood, we will have built the components f
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Training Network for Self-Healing Materials: from Concepts to Market'.

assistant: **Objectives**

The aim of the present Marie Curie project proposal is the development of self-healing materials, the market implementation for the most promising material concepts and developments as well as the training of young scientists and their knowledge transfer in mutual interaction programs due to the distinct interdisciplinary shape of the project.The partners intend to address both actual fundamental research in material development as well as the complementary aspects of conceptual process chain analysis from a more industrial perspective. We have chosen to restrict our research to self healing material concepts with an existing sizeable academic development base and a sufficient number of positive findings to ensure a significant possibility of successful conversion to industrial application. If we succeed in bridging the gaps in knowledge and understanding for these promising materials, industrial development of these concepts and technologies is to be expected. This can only be achieved if specific interdisciplinary training is provided to young researchers, to master the concepts, know how to quantify healing, and how to position these materials in the application fields. Finally, it should be made clear that, notwithstanding the industrial oriented approach in this proposal, the work to be undertaken will always be of the highest scientific/academic character and aims to set a new standard in the development of novel material concepts.The objects of the proposal are-training and education for junior researchers and a strong support for the interdisciplinarity of the project to ensure technology transfer from laboratory research to industrial application-promote actual self-healing strategies an concepts that address current materials or engineering limitations to appl
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Multi-channel biometrics combining acoustic and machine vision analysis of speech, lip movement and face' (SpeechXRays) targeting Horizon 2020.

assistant: **Abstract**

The SpeechXRays project will develop and test in real-life environments a user recognition platform based on voice acoustics analysis and audio-visual identity verification. SpeechXRays will outperform state-of-the-art solutions in the following areas:· Security: high accuracy solution (cross over accuracy of 1/100 i.e. twice the commercial voice/face solutions) · Privacy: biometric data stored in the device (or in a private cloud under the responsibility of the data subject)· Usability: text-independent speaker identification (no pass phrase), low sensitivity to surrounding noise· Cost-efficiency: use of standard embedded microphone and cameras (smartphones, laptops).The project will combine and pilot two proven techniques: acoustic driven voice recognition (using acoustic rather than statistical only models) and multi-channel biometrics incorporating dynamic face recognition (machine vision analysis of speech, lip movement and face). The vision of the SpeechXRays project is to provide a solution combining the convenience and cost-effectiveness of voice biometrics, achieving better accuracies by combining it with video, and bringing superior anti-spoofing capabilities. The technology will be deployed on 2000 users in 3 pilots: a workforce use case, an eHealth use case and a consumer use case. The project lasts 36 months and is coordinated by world leader in digital security solutions for the mobility space.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Environment Friendly & Hardness Enhanced Pvd CrN/TaN Superlattice C oating Technique as a Novel Alternative to Plated Hard Chromium' to be submitted under Fourth Framework.

assistant: **Abstract**

Fine scaled multilayer and superlattice structured TiN and TiAIN based PVD hard coatings have shown increasingly high potential to enhance hardness considerably. Hardness values up to HK 5200 have been reported. In the Exploratory Award project BRST CT95 0119 the feasibility of CrN based superlattice structures has been evaluated successfully with TaN, NbN and TiAIN as partner materials. Hardness values between HK 3500 to 4000, with critical load values of Lc 2 40N at a deposition temperature of 200 C have been found. The introduction of Ta and Nb was intended to improve the chemical and corrosion properties in comparison to CrN whereas the combination with TiAIN should sustain the high oxidation resistance of CrN at temperatures up to 700 C . In the industrial research project NEWCHROME it is planned to explore this promising coating system using the environmentally friendly combined arc/unbalanced magnetron PVD technique. Fundamental research will be combined with broad industrial development activities by suppliers and end users. Diversification into combination coatings:  NEWCHROME Al2 03;  NEWCHROME a Carbon  NEWCHROME MoS2, as well as the investigation of conventional arc technology as superlattice deposition method will be considered. Comparison with existing techniques such as sputtered CrN and CrC, Plasma CVD a Carbon as well as electroplated hard chrome will be ensured. The geographical location of the partners guarantees a broad penetration into the European automotive, paper, textile, cutlery and engineering components manufacturing industry.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Interventions to Promote Healthy Eating Habits: Evaluation and Recommendations' (EATWELL).

assistant: **Concept**

Obesity has been estimated to cost the EU some €70 annually through health care costs and lost productivity, and additionally over-consumption of salt, sugar and saturated fats and under-consumption of fruit and vegetables cause almost 70,000 premature deaths annually in the UK alone.  Member States have initiated a variety of policy interventions to encourage healthy eating including prohibitions on advertising certain foods to children, promotion of fruit and vegetable consumption, nutrition labelling, dialogue with food industry to improve food product composition and regulation of school meals and public sector canteens to ensure healthy food offerings.  Rarely have these been evaluated in a systematic manner.  The EATWELL project will gather benchmark data on healthy eating interventions in Member States and review existing evaluations of the effectiveness of interventions using a 3 stage procedure: 1. The impact of the intervention on consumer attitudes, consumer behaviour and diets;  2. The impact of the change in diets on obesity and health;  3. The value attached by society to these changes, measured in life years gained, cost savings and QALYs.  Where evaluations have been inadequate EATWELL will gather secondary data and analyse them using models mainly from the psychology and economics disciplines.  Particular attention will be paid to lessons that can be learned from the private sector that are transferable to the healthy eating campaigns in the public sector.  Through consumer surveys and workshops with other stakeholders, EATWELL will assess the acceptability of the range of potential interventions.  Armed with scientific quantitative evaluations of policy interventions and their acceptability to stakeholders, EATWELL will recommend most appropriate inter
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Wanted: Micronutrients! Phytosiderophore-mediated acquisition strategies in grass crops' under Horizon 2020.

assistant: **Concept**

Understanding how plants respond to micronutrient deficiency and which biogeochemical processes are induced at the root-soil interface, i.e. the rhizosphere, is crucial to improve crop yield and micronutrient grain content for high quality food and feed. Iron nutrition by grass species relies on the release and re-uptake of phytosiderophores, which are root exudates that form stable complexes with Fe but also other trace metals such as Zn and Cu. However, neither the importance of phytosiderophores under Zn and Cu deficient conditions nor the interplay of plant responses and rhizosphere processes are well understood as the majority of studies in the past was carried out under ‘soil-free’ hydroponic conditions. In this project, I aim to elucidate the mechanisms controlling phytosiderophore-mediated micronutrient acquisition of barley (Hordeum vulgare) under Zn, Cu, and as reference, Fe deficient conditions, with particular emphasis on soil environments. Barley is the fifth most produced crop worldwide and of great importance in regions that are characterized by harsh living conditions. In a holistic approach, my team and I will apply innovative soil-based and traditional hydroponic root exudation sampling approaches in combination with advanced plant molecular techniques to study the phytosiderophore release and uptake system under different experimental conditions. The chemical synthesis of otherwise commercially unavailable phytosiderophores in their natural and 13C-labelled form will allow us to trace their decomposition and metal solubilizing efficiency in the plant-microbe-soil system to uncover the interplay of plant genetic responses and rhizosphere processes affecting the time-window of PS-mediated MN acquisition. Moving beyond ‘soil-free’ experimental designs of
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Success dissemination and promotion in the mobile domain' (ASAPACTS), addressing dissemination and exploitation.

assistant: **Impact**

Main Objective The main objectives of this project are the dissemination of the results of the ACTS Mobile Domain, and the promotion of the benefits of research into advanced communications. Technical Approach This is to be achieved by the production and promotion of a two-volume book set with companion CD-ROMs covering the whole scope of the ACTS Mobile Domain activities. A variety of supporting dissemination and marketing material will also be produced targeting broader constituencies (e.g., public at large, politicians, governments, parliamentarians). The outputs of this project, because of their varied forms of media, will enable them to be used in conjunction with and in support of special actions for dissemination and exploitation of results. Such actions may include, but are not necessarily limited to, workshops, international conferences, public demonstrations and exhibitions. The combination of books and CD-ROMS, which enable the results to be enhanced with video/audio footage and animations, will be supported with a WWW site dedicated to the promotion of the ACTS Mobile Domain results and achievements. The WWW site will enable access by a broader international audience and will certainly contribute to the promotion of the books. It will also constitute a permanent" repository of the knowledge generated by the Programme. Planned Publications The books, each volume consisting of 500-600 pages, will contain project overviews and summaries of their most important research contributions, edited into a coherent and impressive survey. The companion CD-ROMs will contain more complete repositories of the research results (including detailed results of demonstrations/trials). The first volume will be published end 1999/early 2000, the second end 2000/early 2001, coverin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'DNA nanohydrogel loaded Liposomal formulations for high loading efficiency of antimicrobial drugs against intracellular bacterial and topical biofilm infections'.

assistant: **Objectives**

Dr. Sybil Obuobi was awarded her PhD in Pharmacy at the National University of Singapore (Singapore) in July 2018 and is very excited to pursue a postdoctoral fellowship at the University of Tromso The Arctic University of Norway (UiT, Norway) under the supervision of Prof. Natasa Skalko-Basnet, a renowned expert in advanced drug delivery. Their project will exploit DNA nanohydrogels, as a novel universal platform to improve the loading efficiency of antimicrobials in mannosylated liposomes against intracellular and topical biofilm infections. This approach fills the current research gap for high drug loading innovative systems in nanomedicine and holds great promise to improve drug efficacy against difficult-to-reach pathogens thus, there is immense potential for new patentable technologies/products. This area of research will advance knowledge in antimicrobial drug delivery and the outcomes will appeal to formulation scientists, R&D scientists and people with persistent skin infections that impose significant economic challenge and contribute to the spread of antimicrobial resistance. With access to state-of-the-art equipment and interdisciplinary environment within the participating organisations (UiT, University of Helsinki and BIOTEC Pharmacon ASA) and administrative support, Dr. Obuobi will acquire new skills in life sciences, expertise in state-of the art biofilm models, hands-on teaching experience, transferrable skills in grant/patent applications and project management alongside new knowledge in product development. Against the backdrop of her notable achievements as a young scientist, she has the capacity to attain research growth through this fellowship and will seize this opportunity to diversify her competency, improve her record of publications, gain inde
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Structural basis of co-transcriptional pre-mRNA 3’-end processing' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

RNAs transcribed by RNA polymerase II (Pol II) undergo numerous modifications before becoming export competent mature mRNA. One key step is the addition of the poly-adenine (poly-A) tail, which involves cleavage of the pre-mRNA from the growing RNA chain and the subsequent polyadenylation by poly-A polymerase. This cascade of events is known collectively as 3’-end processing and is one of the least understood steps of mRNA biogenesis. Pol II plays a vital role in recruiting and assembling the 3’-end processing machinery onto the nascent RNA, but the structural basis of transcription-coupled 3’-RNA processing is yet to be elucidated. This project aims to bring together the fields of transcription and 3’-end processing in order to understand how poly-A tails are added onto pre-mRNA in the context of actively transcribing Pol II. The most advanced methods of protein expression in recombinant systems as well as the extraction of complexes from native source will be coupled with state-of-the-art electron microscopy analysis to determine the structural basis of co-transcriptional 3’-end processing. Complementary biophysical methods will be used to map macromolecular interactions, and biochemical assays will be conducted to measure the impact of mutations introduced to characterize this fundamental biological process. The goal of this work is to provide the mechanistic basis for this essential step in mRNA biogenesis, and to understand human diseases that are resulted from aberrations in RNA production and processing.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Empowering Active Distribution Networks: A Sensor-Aided State Estimation Framework (SaSEF) Integrating Dynamic DER Models for Enhanced Grid Resilience and Flexibility' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

Distribution networks (DNs) are overwhelmed by rapid growth of distributed energy resources (DERs), such as solar power on homes, and high-power loads, such as chargers. Most such systems are not under the control or even monitored by grid operators, and their state estimation (SE) is still too inaccurate due to limited data and unproper model. This project develops a sensor-aided state estimation framework (SaSEF) for DNs. The core innovation lies in sensor design, DER dynamic modelling, and state estimator development.First, a contactless sensing prototype with threshold-free event-triggering will be developed to capture the DERs’ dynamic data while addressing the data scarcity and privacy in dynamic state estimation. Then, we will develop a dynamic model of DERs under different control scheme and control switching. After that, we will design a state estimator to incorporate the sensing data and dynamic DERs model. The SaSEF will demonstrate its performance on a hardware-in-loop platform.This project will support the European Union's goals for grid modernization and digitalization, enabling distribution networks to operate as active, self-aware entities. The expected outcomes will also inspire novel applications in monitoring and protection, enhancing distribution networks resilience and flexibility and guaranteeing the last mile to energy users. Additionally, this research will expand the fellow's expertise in advanced state estimation techniques and complicated networks analysis, while also inspiring innovative applications in distribution network monitoring, fault protection and proactive management.


**Keywords:** State estimation, power distribution network, inverter-based resources, contactless sensing, event-triggered sensing, data privacy, hardware-in-loop te