RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Themistius, Heavens and Elements. Interpretations of Aristotle’s Cosmology Across the Ages' under Horizon 2020.

assistant: **Concept**

THEIA is the resubmission of the project “Themistius, Heavens and Elements. Interpretations of Aristotle’s Cosmology Across the Ages” that has received the Seal of Excellence 2019. THEIA is a project on the paraphrase of Aristotle’s De Caelo by the 4th century rhetor and philosopher Themistius. It aims to shed light on Themistius’ presentation of the Aristotelian cosmos, that is contained chiefly in this paraphrase. Its importance in the history of Aristotelianism is beyond doubt, as it is the first complete exegesis of the De Caelo that has come down to us, but adequate study of it has been hampered by the fact that the original Greek is lost: only a medieval Hebrew version of the lost Arabic version, and in a Hebrew-into-Latin version survive. Both are edited, but the Latin is derivative, and the Hebrew text requires a new critical edition. THEIA will edit, translate into English, and comment upon the Hebrew text. Once the task accomplished, this will allow the scholars in the field to get a more complete picture of 4th century Aristotelianism. To the importance of THEIA for the history of philosophy another reason of interest should be added, that concerns the text of Aristotle. The Hebrew version allows the scholar who is conversant with Themistius’ exegetical habits to reconstruct some passages in the Greek original, and to single out the Aristotelian lemmata of the De Caelo interspersed in Themistius’ wording. The retroversion of these lemmata into Greek will provide the philologists with an extremely important piece of documentation: parts of the text of Aristotle’s De Caelo as it was read in the 4th century, i.e. five centuries before the most ancient ms of it. In this sense, THEIA can be considered an interdisciplinary project that, through the reconstruction a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Nephrin in proteinuric diseases development of diagnostics, prognostic and treatement modalities' will create measurable scientific, societal and economic impact aligned with Fifth Framework.

assistant: **Impact**

In spite of its extensive medico economic impact, proteinuria remains a poorly understood symptom of the kidneyglomerular filtration barrier dysfunction. At the same time the incidence of end-stage renal disease is increasing in all European counties with only expensive and untargeted treatments available. Here we will use the most up-to-date findings and techniques of molecular biology combined with the extensively shown expertise at the area proposed, to bridge the findings of basic molecular research to direct patient treatment. The goal is to develop markers suitable for early diagnostics, prevention, progression and prognosis for patients with protenuric diseases. The functional genomics of a key molecule for proteinuria, nephrin, as recently identified, will thus be thoroughly studied and the same potential of the emerging binding proteins evaluated. Devices for early diagnostics and patient segmentation wilI be worked out, devices for cDNA array chips for complete kidney glomerular gene expression developed, the intellectual property rights appropriately protected and connections to diagnostics industry developed.All the main objectives of the project were achieved to a great extent. During the project the original technical annex was modified in the middle of the project. The main reasons for this were that some techniques described in the original technical annex were no longer relevant. In addition, due to some new results obtained in the progress of the project, some research subjects were extended in the project. However, the total workload and focus remained grossly the same although some experimental approaches were left out.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Role of Third Pary Logistics Service Providers and their Impact on Transport' (PROTRANS) under Fifth Framework.

assistant: **Objectives**

Currently the supply chains are being restructured from being national to becoming pan-European and even global. However, this development is partly hampered by the limited ability of the present 3PLs to accommodate the shippers demands with respect to e.g. geographical scope and the scope of services, including intermodal transport. Therefore, the PROTRANS proposal will investigate the role of 3PL providers and their impact on transport. In order to achieve the objectives of this task, the PROTRANS consortium will conduct the following research activities: - map and analyse (SWOT-analysis) the European 3PLs market - detail the most important challenges and determine barriers, success and failure factors - assess the future importance of intermodal transport for the strategies of 3PLs, a.o. based on an intermodal perception index.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Rare Earth  Metal-Organic Frameworks and their Application in Crystal Engineering' (RECRYSTENG).

assistant: **Concept**

Rare earth complexes are involved in a new scientific approach in crystal engineering. The synthesis will include organic, inorganic, and materials chemistry techniques using lanthanide salts and organic linkers as building blocks for the formation of crystalline molecular 3D networks.  Green chemistry methods applying solvent-free solid-solid and solid-gas preparation techniques will be developed for a high-yield low energy production of new crystalline rare earth materials.  Analysis of the new compounds will not only be based on advanced X-ray structure determination using single-crystals and crystalline powders but also on microscopy, thermoanalytical, and spectroscopical analysis of the expected luminescent crystals.  Training and collaborations of the researcher in an industrial company and university working and learning new aspects in the field of polymorph screening will guarantee a deeper insight into the optical and solid-state properties of the produced solids as well as their formation of polymorphs. The combination of the analytical and scientific expertise between the University of Bristol and the collaborators create a unique environment for a new rare earth based research in the field of crystal engineering.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Female Cross-Dressing in Early Modern and Modern Japan, 1750's-1940's' (FCDEMMJ).

assistant: **Innovation**

The FCDEMMJ project aims at investigating the urban culture of female cross-dressing, i.e. the social movement that revolved around the custom for women to wear the clothes and use the body language and the linguistic characteristics the contemporaneous culture reserved to men, that existed in Japan from the 1750's to the 1940's and of the control strategies Japanese governments and police promoted from the 1830's to the 1940's to forbid the practice.The project is interesting as it proposes the first systematical gender historiographical study of the urban culture of female cross-dressing and the opposing control strategies. The project fills an important gap in the state of the art as the available scientific researches have analysed the phenomenon's gender dimension only in in relation to a very restricted number of highly contextualised case studies, thus producing results whose validity is limited to said case studies. The project aims at filling this gap by exploring the gender dimension of the phenomenon in its entirety.The project has a strong expected scientific impact as it will allow to open a new line of research dedicated to the study of the gender dimension of cross-dressing in Japanese history. The project has also a strong expected societal impact as L.G.T.B. rights organisations will be able to use the research results as an historical analogy to criticise and oppose current policies which restrict the gender expression of women and gender non-conforming individuals. Furthermore, the project will produce a great benefit for my career development as it will help me obtain a tenure-track position and create a chair in Japanese Sexuality and Gender History.


**Keywords:** Gender History, Japanese Studies, Cultural History, Social History, Cross-Dressing
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Impacts of Changing Climate on Arctic Shelf Hydrogeology', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Rapidly thawing Arctic permafrost is an important, but poorly constrained, contributor to global carbon budgets and an unknown in the climate change equation. Arctic shelves are critical regions in terms of fluid dynamics due to high organic matter and groundwater fluxes, thin permafrost, and shallow gas hydrate stability zones. Predictive modelling of the Arctic subsurface is challenging due to highly transient multi-physics processes and data-acquisition constraints (related to harsh climate and remote terrains), which lead to critical data sparsity and high uncertainties. Using advanced computational methods, we aim to develop a systematic 'process-level' understanding of how climate-change related warming along Arctic shelves impacts permafrost integrity, ice-layer distribution, sub-permafrost groundwater, and gas and gas hydrate dynamics. We also aim to understand how these processes influence seafloor morphologies (e.g. pingos, pockmarks), which can provide useful proxies for linking (easier to access) seafloor observations with underlying (data-sparse) sub-seafloor processes. Our models and methods will be developed in a highly generalized framework which, within this project, will be specifically applied to study climate change impacts on the fjords of Svalbard in the high Arctic. Beneficiary of this funding will be University of Malta, where the applicant (a mathematician) will receive training in seafloor data acquisition, processing and interpretation, and practical aspects of continental shelf geomorphology and hydrogeology, which will empower her to make meaningful and judicial use of data in her modelling studies. The project goals align with UN Sustainable Development Goal on Climate Action, and our findings will have high scientific and socio-economic im
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Kinases and phosphatases that regulate the activation of mpf during xenopus oocyte maturation' (1994-1998), addressing dissemination and exploitation.

assistant: **Impact**

The maturation-promoting factor (MPF) is a regulatory factor that initiates mitosis by phosphorylating a wide variety of structural and regulatory proteins. MPF consists of a regulatory component, cyclin B, and a catalytic component, the protein kinase p34cdc2 and its activation requires phosphorylation of p34cdc2 on Thr161, and dephosphorylation on Tyr15 and possibly also Thr14. In Xenopus oocytes there is a stock of inactive cyclin B/p34cdc2 complexes (pre-MPF) in which p34cdc2 is phosphorylated on Thr161, Tyr15 and Thr14. The activation of pre-MPF requires dephosphorylation of Tyr15 and probably also Thr14, and these dephosphorylations are thought to be instrumental in the activation of MPF during oocyte maturation . The direct upstream regulators of MPF are the kinase weel and the phosphatase cdc25. The aim of this project is to identify and characterise the protein kinases and phosphatases involved in the activation of MPF during Xenopus oocyte maturation, studying kinases and phosphatases implicated in the regulation of weel and cdc25, as well as the role(s) of cyclic AMP-dependent protein kinase (PKA) in the maturation. The activities that regulate cdc25 and weel in Xenopus oocytes are likely to be widely conserved in other species, and may also have a more general role in the regulation of mitosis in somatic cells. Experimentally, Xenopus oocytes and eggs are an excellent system for the biochemical characterisation and purification of kinases and phosphatases.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Making Sense of the Air in China’s Socialist Industrialisation: producing and communicating airborne hazards, 1949–1976' (SENSEAIR) under Horizon Europe.

assistant: **Objectives**

This action will provide the first historical analysis of occupational health work in a Chinese context. It will focus on changing understandings of airborne risk, illustrating how state-led industrialisation efforts introduced new ways of knowing and controlling dangerous particles in the air and how these were communicated amongst experts and to lay publics. It will analyse policy documents, educational propaganda, popular science magazines, and scientific journals related to the field of industrial hygiene to investigate how this field became an important context for reconceptualisations of the air and its relationship to the body. Industrial hygiene grew into a prominent area of public health in the early People's Republic of China, with workplaces like factories and mines designated as sites for managing health-related and environmental concerns. The emergence of industrial hygiene as a scientific regime for organising people, production, and environments in twentieth-century China has not yet been studied by historians. In centring this field, the action will reveal how the control of infectious disease, dust-related occupational disease, and emerging knowledge about pollution developed alongside new understandings of the air as well as of worker productivity. Addressing a major gap in histories of modern China, it will demonstrate the crucial role of the industrial workplace as a site for the production and dissemination of scientific knowledge. By studying conceptualisations of airborne pathology in the unique setting of socialist China, it will offer novel insights into how the communication of knowledge about risk was reconciled with radical political and economic goals. The action will integrate the history of medicine with histories of labour and environment
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Environmental TRANSFORmations in the context of the last hunter-gatherers and first agropastoral groups of the MEDiterranean Alps'.

assistant: **Concept**

The transition period from the last hunter-gatherers to the first agropastoral groups marked a significant turning point in how humans understood the landscape and their relationship with environmental processes. In this context, the Mediterranean Alps played a key role as a natural corridor connecting the Mediterranean to Central Europe, making the region a hotspot for human mobility and cultural exchange. Notably, this area is highly sensitive to climate fluctuations, and some of these environmental changes may have influenced mobility and resource availability, shaping the cultural dynamics of the Mesolithic-Neolithic transition.TRANSFORMED aims to deepen our understanding of human-environment relationships during this period through a high-resolution interdisciplinary approach. By integrating newly generated decadal-scale palaeoecological and hydroclimatic data with existing environmental and archaeological records into a common calibration model, we will precisely assess the timing of natural and cultural events and help bridge regional gaps in the archaeological record.Comparing the timing of environmental and cultural transformations is essential for understanding how past and modern societies have responded to the challenges of climate change. By examining major cultural shifts within the dynamic landscapes of the past, TRANSFORMED will provide valuable long-term perspectives into human adaptations to environmental changes. Insights from this critical period when humans emerged as a powerful force of change within the Earth system are crucial for understanding and mitigating both the environmental and societal effects of climate change.


**Keywords:** Palaeoenvironment, Mesolithic, Neolithic, Mediterranean Alps, Ecological Transformations
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Incorporation of Aquaporins in Membranes for Industrial Applications' (MEMBAQ), addressing dissemination and exploitation.

assistant: **Impact**

In all living cells, channels transporting water - aquaporins - exist. They are proteins, which only transport pure H2O molecules. They have a unique selectivity and are extremely efficient being nature's own membrane systems. The purpose is to investigate whether these unique features can be industrially exploited: Recombinant aquaporin molecules will be embedded into water filtration membranes. Nano-biotechnological research of water transport in various organisms shows that aquaporins have 100% selectivity: Only water molecules pass. They also maintain high water permeation rates. Membrane technology is another rapidly developing technology within filtration and separation. Substantial research is done to enhance efficiency of membranes.The MEMBAQ project combines these two research spearheads. This combination has never been done before. A new filtration membrane with aquaporins is in theory up to 50 times more efficient (energy input reduction). It is truly radical innovation of the water industries, for instance for water purification (billions of EUR is spent every year), salinity gradient energy production (exploitable potential is 2000TWh annually), waste water reclamation (water re-use).The MEMBAQ project will:1) produce recombinant aquaporin,2) design nanotechnological membrane by means of computer simulation,3) incorporate aquaporins into stable membranes,4) engineer membranes based on characterising towards pressure, ph etc.,5) and finally test such membranes in three applications: Water purification, osmotic energy, and waste water reclamation for re-use. US and Japan invest significantly more per capita than EU in nanotechnology.This gap is expected to widen in the next few years. In MEMBAQ, we use real market needs in the water sector as a driver for acc
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Semisynthesis of caged a-Syn' (SEMISYNTHESIS).

assistant: **Innovation**

The overall objective of this proposal is to determine the effect of specific disease associated post-translational modifications, more specifically phosphorylation and nitration, on modulating the structural and biochemical properties of a-synuclein. In detail, we plan to assess the effect of these modifications on i) the structure of monomeric and membrane bound a-synuclein; ii) the oliogmerization and fibrillogenesis of a-syn; iii) subcellular localization and targeting of a-syn to specific cellular compartments. Towards this goal, we plan to use a combination of chemical biology and semisynthetic strategies to 1) synthesize a-syn variants that are modified at specific sites 2) make use of caged amino acids and fluorescent tags to allow temporal and spatial induction and control of post-translational modification in living cells.