RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Autoantigen-specific adoptive regulatory T cell therapy against type 1 diabetes (ARTiDe)' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

Type 1 diabetes (T1D) is an incurable disease, often starting in childhood, with a risk of devastating complications, premature mortality, and high social burden. It is caused by the autoimmune destruction of insulin-producing beta cells, yet the standard of care is insulin replacement, acting only at the symptom level. Thus, T1D is a disease with a high unmet need for innovative therapy. Ideally, such therapy shall suppress selectively the immune cells driving T1D without impairing protective immunity. Regulatory T cells (Tregs) are the guardians of human immune tolerance, and genetic defects in Tregs are associated with T1D. Tregs additionally possess tissue regenerative capacity, making them ideal to treat T1D in cell therapy. However, such therapy, performed with polyclonally expanded patient Tregs, showed limited efficacy in T1D. These expanded Tregs are however poor in relevant autoreactive Tregs to save insulin-producing cells. In fact, the identification and manufacturing of autoreactive Tregs remain fundamental technical challenges to successfully apply these cells in the clinic. ARTiDe aims at a breakthrough in antigen-specific Treg therapy in T1D by establishing the production of human Tregs genetically engineered to express an autoreactive T cell antigen receptor (TCR) ready for clinical use. To achieve this ambitious goal, ARTiDe combines the complementary expertise of 8 partners providing novel technologies for the systematic identification of autoantigen-specific Tregs in humans, the selection of optimal TCR to produce protective Tregs, and innovative humanized T1D pre-clinical models to test their efficacy and safety, as well as Treg supporting strategies, in vivo. World-leading biotechs for adoptive T cell therapy will establish novel GMP-compatible man
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'An Interregional PhD Programme for Advancing Sustainability and Climate Resilience in Occitania, Balearic Islands, and Catalonia'.

assistant: **Objectives**

TERRA-MED is a joint interregional initiative led by the Euroregion Pyrenees Mediterranean (Euroregio), a grouping of three EU regions of the south of EU : Occitania Region in France, Catalonia and Balearic Islands governments in Spain. Altogether, Euroregion's territory forms a cutting-edge research and innovative ecosystem with many research and academic institutions in the world's top ranking.  The 3 cross border territories are particularly affected by the compounded impacts of climate change, which are disrupting resources and systems. To respond to the vulnerability of these territories to climate change, EUROREGIO actors are joining forces in this doctoral program focusing on the WATER – LAND – ENERGY nexus.  TERRA-MED's Interregional doctoral program will train 33 promising researchers to face these challenges and pave the way for sustainability and resource efficiency in Mediterranean regions. This multidisciplinary doctoral program aims to train the next generation of research talents that will tackle the pressing challenges in our climate change affected regions. Recruited fellows will benefit from the Euroregio research and innovation ecosystem and will work interregionaly: all PhDs fellows will be jointly supervised by academics and non-academics, with mandatory cross border or international secondments. TERRA-MED will strongly promote co-thesis arrangements. A specific training program jointly designed and implemented by the 12 Implementing Partners and 22 Associated Partners will build the basis of the future careers of the fellows with transversal and socials skills as well as a highly specialised research training.


**Keywords:** Mediterranean Interregional PhD Programme, Climate change , WATER – LAND – ENERGY nexus, Cross-border Cooperation
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'DEVELOP-MENTALITIES – Islamic and Islamist Views of State, Society, and Economics in Yemen' under Horizon Europe.

assistant: **Concept**

How applicable are economic development models, approaches, and policies of the EU to the ideational, political, and structural conditions of Middle Eastern societies? This project provides answers to this question by examining Islamic and Islamist views on state, society, and economics in Yemen  the poorest country in the MENA region. The project contrasts divergent ideas of development among Yemens Islamists-in-exile, focusing on the Houthis, the Salafis, and members of al-Islah living in Turkey, Saudi Arabia, the United Arab Emirates 8UA), and Oman, comparing local ""develop-mentalities"" with those prevailing among Western donors. It leverages the momentum of the slowdown of hostilities enabled by the recent Iran-Saudi deal, and the ongoing Saudi-Houthi negotiations, through an innovative methodology that combines concepts and approaches from Oral History, ethnography, economics, and politics. Academically, the project breaks new ground in the field of Islamic and Islamist economics by enriching our understanding of how political actors in the Global South think about state, modernity, globalization, and capitalism. It thereby contributes to Yemens history since 2011 while enriching our understanding of MENA geopolitics with new subaltern perspectives of the southern Arabian Peninsula. It further sheds light on the intersectionality between the epistemic universes of Western development theory and practice, and its applicability and receptivity in a complex, war-torn society that is dominated by tribalism and power politics. The secondary objective is to make a tangible contribution to the EUs current efforts to transition beyond humanitarian, and towards economic, forms of development policy. By creating an unofficial line of communication between Yemen's Islamists
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Innovative IT tools for a circular textile economy: driving sustainability and resource efficiency.' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

The AIdesignTEX project aims to enhance the research profile of  Łódź University of Technology (TUL) FMTTD in sustainable textile production by leveraging artificial intelligence and machine learning tools to develop easily recyclable or biodegradable textiles. Through networking and partnership activities with EU counterparts, such as Stavanger University (UiS), Ghent University (GU), and the Catholic University of Avila (UCAV), TUL researchers seek to expand their knowledge of the circular economy principles and their application to textile production. The project aligns with the goals of the European Green Deal, which aims to promote a circular economy and reduce waste. The textile industry is a major contributor to environmental pollution, with large amounts of water consumption, CO2 emissions, and waste production. By implementing AI and ML tools, the project seeks to help textile producers adopt sustainable practices, save resources, and minimize environmental impact. During long-term visits and complementary activities with the advanced partners, TUL researchers will acquire expertise in sustainable technology, eco-design awareness, and administrative skills. Upon completion of the visits, TUL researchers will conduct training sessions for businesses and stakeholders in the Łódź region to share their newly acquired knowledge and skills. This knowledge dissemination will foster interest in cooperation and joint development of a Future Plan for sustainable textile production. Coordination and support activities will include lectures, workshops, and training sessions for experienced TUL researchers and ESRs to disseminate the gained knowledge and skills within the institution and beyond (Polish textile companies and interested entities from Asian countries).


**Key
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Comprehensive code for stellar dating, and analysis of exoplanetary systems observed by direct imaging' in the context of a Horizon 2020 call.

assistant: **Objectives**

THOT is an ambitious project for delivering estimated ages for large numbers of stars in the Galaxy. The main aims of THOT are: 1) To gather all the techniques for stellar dating, 2) to update those having the most potential for application to data from new and upcoming missions, 3) to develop a code to automate stellar dating and, 4) to apply this code to study exoplanetary systems observed by direct imaging. This ambitious programme will be delivered at the University of Birmingham (UoB) by Dr. Moya, supervised by Prof. William Chaplin in close collaboration with Drs. A. Miglio and G. Davies. A two-year plan including working packages, deliverables, milestones, and training objectives is presented, showing the feasibility and innovation of the project. THOT has three secondments planned at different academic institutes: 1) CAB – INTA/CSIC, Spain, Dr. David Barrado, 2) IA, Portugal, Dr. Elisa Delgado, and 3) UNED, Spain, Dr. Luis Manuel Sarro. These secondments complement the needed skills for the project and open key collaboration lines for THOT and for the long-term project for which THOT is the first step: an EU collaboration network for stellar dating and the development of a “map of ages” to understand how the region of the Galaxy around our Sun evolves. Because of his career, Dr. Moya will be able to make the most of this fellowship opportunity. The Solar and Stellar group, led by Prof. Chaplin at UoB, is the best option for him to deliver success. The proven leadership and independent thinking of Dr. Moya, together with the new opportunities and skills that the UoB research group offers, will provide a major boost to Dr. Moya’s scientific career. A complete plan for dissemination, exploitation and communication of the results is also presented. The UoB is commit
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Development and testing of membranes for biohybrid systems' (1994-1998), addressing dissemination and exploitation.

assistant: **Impact**

The main outcome of the project is documented in three patent applications. The first patent already granted in Germany (Verfahren zur Erzeugung, zum Transport und zur Eliminierung von biochemischen Stoffen mittels aktiver biologischer Zellen. DE 199 43 205.8-41, European patent application EP 1090 984 A2) describes a method and device for production, transport and elimination of substances with the help of living cells in a so-called fibre-in-fibre bioreactor where tissue- and blood-compatible membranes can be combined. This bioreactor was successfully applied for kidney epithelial cells with the hollow fibre membranes described in the second patent. An up-scaling of the initial bioreactor prototype having only 4 fibre-in-fibre pairs was done with a bioreactor containing 16 units that was tested with hepatoblastoma cells. A more up-scaled fibre-in-fibre device was developed based on the Fresenius standard modules which has a great capacity to be used in biomedical applications. A project for the development of a biohybrid kidney based on this bioreactor type is under preparation. Experiments at GKSS and FU-IP are under work to investigate the application of the bioreactor for the production of monoclonal antibodies by hybridoma cells.In a second patent (Membranes made from P(AN/NVP)-copolymers with both haemo- and tissue-compatibility and their application in medical field. German patent application DE 100 30 307.2, European patent application 01115145.3-2113) a bulk polymer composition is described that possesses both blood- and tissue-compatibility. Membranes made of theses polymers can be used in BHOs with fibre-in-fibre design, especially for kidney assist or replacement.The third patent submitted deals with a new group of acrylonitrile copolymers that possess high
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'COMPUTATIONAL TECHNIQUES FOR ECONOMIC GROWTH AND MANAGEMENT PROBLEMS' (2002-2006).

assistant: **Innovation**

Computational economics is an emerging branch of economic theory, which studies how the equilibrium can be efficiently computed. The search of a major realism in growth and business cycle models is pulling macroeconomists to consider more complex dynamic stochastic specifications, which requires the use of efficient numerical optimisation methods. The unifying theme of this proposal is the development of computational approaches for solving dynamic optimisation problems, and their application to general and realistic growth and business cycle models. Similarly to macroeconomic problems, business decision-makers face dynamic stochastic problems. An additional aim of this project is the application of these numerical methods to management decision, focusing on the robustness against unobserved shocks that might affect the decision outcome. This aim extends some previous work of the applicant on management decision in deregulated electricity markets. Furthermore, this proposal is concerned with the design of a robust procedure for calibrating parameters of macroeconomic models when the available empirical information is incomplete. The robustness in the calibration of the model is achieved by a worst-case approach. Worst-case modelling consists of essentially designing the best model that fits as much as possible to the available data in view of the worst-case scenario of unobserved decision variables. This is a key issue in many managerial problems.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Bridging the micro-macro gap in population forecasting' goes beyond current state-of-the-art under Sixth Framework.

assistant: **Innovation**

The provision of high quality and sustainable health care services and pension systems require an instrument to monitor and forecast demographic change. The aim of this proposal is to develop that instrument. The methodology consists of a macro-model MAC that models demographic changes at the population level and a micro-model MIC that models demographic events at the individual level. Mac extends the cohort-component model to a multistate model that considers transitions in life other than birth and death. The transitions determine the distribution of cohort members among functional states. The output of MAC consists of cohort biographies. The aggregate level of Mac is adequate for most regular demographic projections. MIC addresses demographic events and other life transitions at the individual level. It is a micro-simulation model that produces individual biographies. That level is required to project very detailed population categories and to assess the potential impact of policy interventions on the occurrence and timing of demographic events in life. MIC and MAC can work independently but they are more effective if they work as a team. They will be used to address policy questions such as the provision of health care services in an ageing population with morbidity expanding or compressing, or the provision of pensions in an ageing population with age at retirement declining or increasing. Methods are developed for estimating transition rates from census data, vital statistics and survey data. Data shortage will be overcome by parameterised projections using model schedules, i.e. mathematical models of age-specific rates of transition. User-friendly software will be developed, including a library of algorithms (objects) that are applied in the models. Hands-on trai
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'Legal and regulatory measures for sustainable transport in citiesat'.

assistant: **Objectives**

LEDA is a research project to study legal and regulatory measures to promote sustainable transport in cities. The scope is encompassing measures in the transport sector, but also in related sectors influencing transport demand and supply like environment and land-use planning. The focus is on passenger transport.All kinds of legal and regulatory measures concerning urban transport and related areas will be included in an inventory of measures that are currently being used in a selection of 40 European cities. About 20 of the most innovative, effective and less well-known measures will be analysed in depth. Research will include aspects like public responses, enforcement requirements and aspects related to accompanied measures. A temptative framework to analyse the transferability of the measures will be established.Much effort will be laid to derive guidelines addressed to urban authorities on how to implement the most effective measures, and on recommendations addressed to the regional, national and European authorities on the possible changes in the legal frameworks.The instruments planned to support the dissemination of the results are a website, a CD-ROM with the database, brochures, an international conference and round table conferences in each partner country in order to initiate a debate on the appropriateness of changing the legal frameworks. The whole process will be accompanied by four Regional User Groups, which together cover all the Member States and CEEC countries. refoldi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Fertilization effect of Aerosols on earth BIOmass' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Atmospheric aerosols have an important role in the energy balance of earth system, yet not all their interactions have been fully studied, especially the aerosol fertilization effect on the terrestrial and marine ecosystems. This proposal is targeted to quantify the response of natural terrestrial and oceanic productivity to the atmospheric deposition of ammonium aerosol and iron-rich dust particles. It involves the coupling of a global chemistry-aerosol model within an Earth System Model that includes the carbon cycle in the terrestrial and marine reservoirs. In the proposed research, important knowledge will be transferred from the third country (China) to the host institution in France, including a new dataset of gaseous and aerosol species emissions, coupling of aerosol and vegetation models, and simulation of the fertilization effects of aerosols on marine and terrestrial ecosystems. This proposed research is expected to enhance the Earth System Modeling in the host institution and increase European competitiveness in climate change study. This research can lead to potential breakthroughs in our understanding of the influence of nitrogen and iron on carbon storage.