RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Enantioselective C-H Oxidation Guided by Rational Catalyst Design' (ECHO-GRACADE).

assistant: **Innovation**

Chemo- and enantioselective oxidation of aliphatic C-H bonds is a cornerstone reaction in metabolism. The ubiquitous presence of multiple and diverse C-H bonds in organic molecules is used by oxidative enzymes to deliver functionality and chirality to metabolite precursors, rapidly creating product diversity. Despite its huge potential in organic synthesis, non-enzymatic enantioselective C-H oxidation of aliphatic sites remains inaccessible and has never been incorporated in synthesis. Harnessing the power of this reaction will open straightforward, yet currently inaccessible, paths in synthetic planning. However, realization of this goal requires conceptual breakthroughs in order to chemo-, regio- and stereo-selectively create a C-O bond from a non-activated alkyl C-H bond, even in the presence of a priori more reactive groups. In this project, chemo-, and site-selective asymmetric aliphatic oxidation is targeted by taking advantage of; a) stereoretentive enzyme-like metal-based C-H oxidations performed by small molecule manganese catalysts, devised as minimalistic hydroxylases, and b) polarity reversal exerted by fluorinated alcohol solvents in electron-rich functional groups, which enable chemoselective C-H hydroxylation of densely functionalized molecules. Desymmetrization via enantioselective C-H oxidation is devised as a powerful type of reaction that will create multiple chiral centers in a single step. Building on the rich chemical diversity and modular architecture of aminopyridine manganese complexes, rapid elaboration of libraries of catalysts is targeted. Rational manipulation of steric, electronic, directing effects and supramolecular substrate recognition factors guided by multiple parametrization analyses will be employed for directing evolution in cataly
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'STable perovskite solar cells via interfacial engineering of 2D/3D mixed-dimensional Absorbers and Robust dopant-free hole transporting materialS' (STARS).

assistant: **Innovation**

The growth of perovskite in the photovoltaic field is unprecedented. In only a very few years, the power conversion efficiency (PCE) raised from 3.8% (in 2009) to 23.3% (in 2018). However, before bringing PSCs to an industrial scale-up process, major issues need to be addressed, among one of the most concerns the lack of stability against IEC61646 accelerated aging protocol. Improving stability is at the heart of the STARS project. To achieve such an important goal, STARS combines two main approaches: (i) Development of 2D/3D mixed-dimensional perovskites via interfacial engineering and (ii) development of robust dopant-free hole transporting materials (HTM). Fellow’s knowledge of HTM synthesis and device processing will be highly beneficial for Prof. Hagfeldt (host) research activities which are mainly focused on the development of new materials and molecular engineering of interfaces to achieve stability. STARS is designed to expand/broaden fellow’s knowledge towards device aging, crystallography, and photophysics. STARS will add several new dimensions to fellow’s skill set and instill leadership qualities and management skills that will be extremely beneficial for his future career.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Model-based Design of Secure Cyber-Physical Systems' (MODESEC), addressing dissemination and exploitation.

assistant: **Impact**

The objective of MODESEC is to develop a design methodology that integrates security in the model-based design (MBD) process of cyber-physical systems (CPS). The research is based on the insight that security engineering is a vital part of the system development process and cannot be treated incidental. The model-based design flow is a computer-aided design method that extensively uses models to analyse and determine functional and non-functional properties of the desired artefact during its design phase. The proposed methodology will extend current MBD approaches for security. A peculiarity is that the methodology will make use of the application-specific information contained in the functional models to implement a custom security architecture for the desired system functions of the CPS. For this purpose, relevant information is extracted from the models representing the CPS. This information is then used to configure and to adapt security mechanisms aimed at the prevention as well as the detection of attacks. The security mechanisms are installed together with the application’s system functions on an appropriate computing platform. The developed secure MBD methodology will be implemented within the scope of a state-of-the-art MBD tool chain. It will be evaluated by conducting a case study within a System-of-Systems (SoS) context (e.g., the Smart Power Grid), because this research field combines security and dependability requirements in a new, unique, and challenging way. The secure design methodology developed within MODESEC will support MBD practitioners to improve the security of their products.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Dynamics and stability of reed-dominated ecosystems in relation to major environmental factors that are subject to global and regional anthropogenically induced changes.' will create measurable scientific, societal and economic impact aligned with Fourth Framework.

assistant: **Impact**

Reeds are dying back at a fast rate in sizable areas of Europe, with significant impacts on important wetland functions (biodiversity, stability of river and lake margins, water quality) and local economies. EUREED II is a three-year strategic fundamental research initiative that aims at analyzing the mechanisms which control the growth dynamics and stability of reed-dominated ecosystems, at modelling and predicting how the ecosystem is disturbed by human activity and climate change, and at developing remedial management options. Expected achievements include (i)assessment of the functional role of reed-dominated ecotones as nutrient accumulators and transformers and as sources for atmospheric greenhouse gases, (ii) an ecosystem model capable of predicting future changes in ecosystem functioning in relation to climatic conditions, trophic status and water table management, (iii) assessment of genetic diversity of reed populations and its relation to die-back, and (iv) development of management tools, including preventative and restQrative measures in relation to die-back. The scientific approach of the workprogramme is multi-disciplinary and co-operative, and comprises observational field studies, field experiments, controlled greenhouse and laboratory experiments, data collation and treatment, and mathematical modelling. A significant part of the studies is carried out during multi-disciplinary workshops. The project is carried out by research groups with complementary skills and expertise from nine European countries. A reference site is selected in each country as the basis for the field studies. The reference sites cover boreal-mediterranean and oceanic-continental climatic gradients, and the observational and experimental studies at these sites permit interpolation
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'SweNet Innovation Specialist and Key Account Manager Service' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

The Swedish consortium working with Enterprise Europe Network will deliver services within the action ”Establishing services enhancing the innovation management capacity of SME’ in the Enterprise Europe Network” during 2014 and onwards. This proposal only covers services to be delivered during 2014 even though services to involved SMEs will proceed in 2015 to 2020. The project will involve six partners where The Swedish Agency for Economic and Regional  Growth will be the coordinator. Swerea, Acreo and Centek will be the partners delivering services, both as Key Account Manager and as Innovation Specialists. Partners ALMI Mitt, SIK and Uminova will be involved in a reference group together with the NCP for SMEs. This application consists of four work packages: WP0 Integrate the KAM and EEN Innovation specialist services with the national supporting system for innovation and H2020WP1 Provide Key account management (KAM) services for the beneficiaries of the SME InstrumentWP2 Provide Innovation specialist services for selected SMEs to enhance their innovation management capacity.WP3 Manage the WP processes, tool development and training In total there will be six employees from Swerea, Acreo and Centek that will be delivering the services in WP 1 and 2 during 2014. The estimated number of SMEs participating in 2014 are 50 were 10 is coming from the SME Instrument and 40 will be selected for innovation management services. The selection will be made by a reference group in consensus to ensure that  selected companies have a high growth potential. We will take into account both branch experience and geographic closeness to be able to signpost clients to the most appropriate partner.The tool to be used for enhancing innovation management capacity will be IMP3rove. The tool t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Facilitating Innovations for Resilient Livestock Farming Systems' under Horizon Europe.

assistant: **Concept**

The overall objective of Re-Livestock is to evaluate and mobilize the adoption of innovative practices applied cross-scale (animal, herd, farm, sector and region) to reduce GHG emissions from livestock farming systems and increase their capacity to dealing with potential climate change impacts. To reach our aim, Re-Livestock have brought together the excellence scientific expertise in Europe and Australia and across disciplines, including co-innovation, animal feeding, breeding, welfare, farm management, environmental and socio-economic assessment and policy analysis, to develop novel and scientifically supported integrated approaches specific for different dairy, beef and pig systems and geographic regions in the context of climate change. Strong collaboration with industry stakeholders to identify the innovations and to co-design the validation will ensure relevance and maximise the adoption of best practices. National groups of farmers (case studies) and ‘stakeholder forums’ together with a ‘European multi-actor platform’ will allow for an engaged co-design of transition pathways whilst ‘learning from innovation networks’ will allow for the testing and sharing of latest innovative solutions. A ‘community of practice’ will extend the multi-actor approach to a broad range of stakeholders.


**Keywords:** Livestock, Mitigation, Adaptation, Climate change, Co-innovation, Adoption, Farming systems, Resilience, Circularity
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Novel bio-inspired energy harvesting and storage all-in-one platform for implantable devices based on peptide nanotechnology' (PepZoPower) under Horizon Europe.

assistant: **Objectives**

Over the past decades, implantable biomedical systems have greatly advanced, offering previously unavailable therapeutic options for millions of patients worldwide. Such applications most commonly utilize conventional lithium-ion batteries as the energy source. However, while readily providing adequate energetic performance, lithium-ion batteries are inflexible, rigid, may contain toxic substances, and require periodic replacement surgeries due to their limited capacity, posing both health risks and an economical burden. Here, aiming to address these issues, we will develop PepZoPower, a biocompatible energy harvesting, and storage device designed for biomedical applications. Energy harvesting will be facilitated by highly-efficient piezoelectric peptide-based assemblies allowing to harvest mechanical energy from the human body and convert it into electric energy. The harvested mechanical energy will be stored by a biocompatible peptide-based supercapacitor, thus giving rise to an autonomous, miniaturized, controllable, and biocompatible power device with adequate performance and mechanical properties. This ambitious goal will be achieved by utilizing our patent-protected piezoelectric and energy storage peptide-based supramolecular structures, to be incorporated into an integrated device. The performance of each layer will be optimized and the integrated PepZoPower device will be validated to verify efficient incorporation of the two components. We envision the breakthrough PepZoPower technology to serve as the basis for the next leap toward biocompatible, soft, miniaturized, light-weight and morphologically-controllable implantable devices. This will pave the way towards post-project commercial exploitation of the PepZoPower system, which will be further developed by
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Clinical research for the validation of a non-invasive medical imaging device for dermatological diagnoses' (DERMAE).

assistant: **Concept**

Diagnosis and study of many diseases in dermatology, including cancers, mainly depend on biopsy and histopathological analysis of tissue at the cellular-level using an optical microscope. This medical procedure implies to perform a biopsy, i.e. to excise a portion of tissue, then to freeze and cut the sample into slices of a few micrometers thickness and use specific dyes. This procedure is painful and potentially dangerous for the patient. Moreover it is time-consuming and may introduce structural deformation or damages.Skin diseases like Melanoma are rapidly growing throughout the world. About 12 millions biopsies are performed each year by dermatologists. As a minor surgical act, the biopsy process involves pain, possible scarring, and stress during the 15 days before reception of analyses results. In 60% of the cases, the skin anomaly is benign and do not necessitate further treatment. However, the patients need to consult another time with the dermatologist for the announcement of the results of the biopsy, which incurs extra medical costs and time. Moreover, as symptoms are detected on a macroscopic-level with surface criteria (color, form and size of the lesion), the dermatologist misses over one third of the pathologies. Finally, as the tissue excision is visually performed, 40% of reoperation is necessary to remove the entire tumor.DERMAE is a highly recognized and awarded innovative project that solves this major healthcare issue by developing an innovative instrument capable of producing in situ images of biological tissues similar to histological sections. This non- invasive imaging technique will be able to image in real time the internal structures (up to 1 mm deep) of biological tissues at the cellular level (about 1 μm resolution). This imaging technolog
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Macromolecular Ion-Solvent Interactions in Charged Droplets' (MISICD) targeting Seventh Framework.

assistant: **Abstract**

We use computational and analytical methods to study the factors that determine charge state of macromolecules in droplet, gaseous and bulk environments and the relation of the charge state to the conformations of the macromolecules. Practical applications of the study are found in electrospray mass spectrometry (ESMS), which is an analytical technique used for the analysis mainly of biological molecules such as proteins, DNA, poly-saccharides. To understand the processes that take place in electrospray ionization, knowledge of the charging and the conformations of a macromolecule is required in bulk, droplet environment and gaseous state.The factors that determine the charge state distribution of the macromolecules in the droplet include the interactions between the analyte and the solvent in the droplet environment, acidity changes in the droplet, evaporation rate of the solvent vs. deprotonation rate of the macroions in the droplet, release mechanisms of macroions from droplets, and details in the operation of the electrospray instrument. We use advanced molecular simulation methods to study rare molecular fluctuations in the solvent and macromolecules that are central in describing quantitatively the above processes. These rare fluctuations are captured by methods for study activated processes in statistical mechanics. The study aims at understanding fundamental processes in the charging of macromolecules and laying the theoretical foundation for processes that give rise to the signals in the ESMS methods. The computational methodology that we develop for the sampling of the conformational changes can be used in a broader class of problems than those we study. Moreover, our studies in the gas-droplet and bulk environment will enhance our knowledge on the interaction
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Engineered Protein Nanosheets at Liquid-Liquid Interfaces for Stem Cell Expansion, Sorting and Tissue Engineering' (ProLiCell).

assistant: **Innovation**

A long standing dogma in the field of cell-based technologies is that bulk mechanical properties of solid substrates are essential to enable cell spreading, proliferation and fate decision. The use of solid materials to culture adherent cells constitutes an important hurdle for the scale up, automation and speed up of cell culture and recovery. Our recent results show that bulk solid substrates are not necessary to promote cell adhesion, growth and fate regulation as adherent stem cells spread and proliferate readily at the surface of ultra-soft materials, even liquids. In such cases, cell adhesion is enabled by the formation of a mechanically strong layer (nanosheet) of proteins at the interface between the oil (liquid substrate) and aqueous medium. This key discovery opens the door to the engineering of protein nanosheets enabling the use of liquid, free-flowing substrates sustaining cell adhesion, expansion, isolation and recovery. ProLiCell will design the biochemical and mechanical properties of extracellular matrix (ECM) protein nanosheets that can sustain the formation of adhesion protein complexes and support cell proliferation and culture on materials with very weak bulk mechanical properties (liquids). The engineered ECM nanosheets will be applied to: 1. the design of 3D bioreactors based on emulsions, for the culture of stem cells; 2. the formation of stem cell sheets at oil-water interfaces for tissue engineering; 3. the isolation and purification of stem cells using emulsions presenting antibody-adsorbed interfaces. ProLiCell will provide fundamental insights into ECM nanosheet design and advance our understanding of the mechanisms via which cells adhering to such interfaces sense and respond to nanoscale cues. Such fundamental understanding will enable liq