RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Sixth Framework proposal for the project 'Investigation of the role of activin in mesoderm induction in Xenopus'.

assistant: **Objectives**

The mesoderm of the amphibian embryo is induced by signals derived from the vegetal hemisphere of the embryo, which act on overlying equatorial cells. This proposal investigates the role and mode olfaction of the mesoderm-inducing factor active; recent experiments using antisepses morpholinooligonucleotides have shown that active is required, in a dose-dependent fashion, for normal mesoderm formation. We shall first use DNA microarray to identify genes that are down regulated in embryos in whichactivin signalling is reduced or abolished. The expression patterns of genes identified in this way will be investigated by in site hybridisation and their responses to different levels of active signalling will be studied. The 5' regulatory regions of active target genes will be analysed to ask if they share common motifs or transcription factor binding sites. The second series of experiments investigates the range of active signalling; experiments in whichactivin is miss-expressed in ectodermic tissue indicate that active can exert its effects over many cell diameters. However, it is important to know the range of endogenous active signalling in the intact embryo and whether this varies in different regions of the embryo. This will be studied by making clones of cells in which active translation is inhibited and asking to what extent neighbouring cells can rescue' target gene expression in those cells. The third question concerns post-transcriptional regulation of active; the effects of active are exerted predominantly in the vegetal hemisphere and marginal zone of the embryo, but active B mRNA is expressed in the animal hemisphere as well as in vegetal cells.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Advanced BIObased polyurethanes and fibres for the autoMOTIVE industry with increased environmental sustainability' (BIOMOTIVE).

assistant: **Concept**

Vehicles are composed by different materials and a noticeable and fundamental fraction of them (20% w/w) is constituted by plastic material, among which polyurethanes. PU is fundamental since, thanks to its properties, it enables to reduce the overall weight of the car, resulting also in a lower fuel consumption. More and more vehicles’ manufacturers and suppliers are betting on biobased alternatives derived from renewable raw materials, but a biobased plastic able to mimic technical properties of PUs as well as to provide the required aesthetics and haptics has not been developed yet. The BIOMOTIVE project will pave the ground towards the production and subsequent market penetration of biobased automotive interior parts with enhanced technical performance, improved environmental profile and economic competitiveness, with the aim of replacing the fossil-based, non-biodegradable counterparts. Within the project, innovative and advanced biobased materials with an increased biobased content (60-80%), i.e. thermoplastic polyurethanes, 2-components thermoset polyurethane foams and regenerated natural fibres, will be produced starting from renewable biomass feedstock not in competition with food and feed, leveraging innovative production techniques. Such materials will be validated into cars’ interior parts (door handles and automotive seats) demonstrating advanced properties in terms of resistance to fire, mechanical strength and flexibility as well as improved recyclability of the end-of-life products. The project will also aim at demonstrating an innovative process for the production of up to 80% biobased NIPUs, with moisture-repellant properties. The involvement of external industrial players thorough targeted dissemination events will pave the ground to the widening of t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for '“Social Studies Teachers’ Understanding and EthicalDiscussion of Political Violence and Nonviolence”' under Seventh Framework.

assistant: **Concept**

This research project proposes to investigate how social studies teachers understand the use of violence and non-violence as social and political tools to meet personal of group needs, and to manage the conflicts that may arise.More specifically, it proposes to examine the social discourses communicated through history textbooks, and the critical thinking and discursive processes that teachers display, when reflecting or participating in controversial conversations about the uses of violence and non-violence in the history of their countries, and in their current societies. The study examines too how teachers view the teaching of these topics to youth.The study is situated in the intersection of three scholarship fields: Peace and Conflict studies, peace education, and history education. The research project is conceived as a comparative qualitative study, conducting research in three different countries (Spain, Colombia, United States) that have particular histories and experiences of social and political violence and non-violence, current and historically. The comparative study is supported by collaboration with colleagues in these countries included.Investigating this problem will afford insight into key psychological and cultural elements that sustain violence or non-violence. With this furthered understanding, better educational resources and interventions will be developed.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Respiratory Epithelial Memory: Uncovering the role of trained immunity in the respiratory epithelium' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

Immunological memory, once thought to be exclusive to the adaptive immune system, is now increasingly recognized as a feature of innate immunity. This phenomenon, known as trained immunity, enables innate immune cells to undergo lasting functional changes after an initial infection, improving their response to future immune challenges. While trained immunity is well characterized in some cell types, its role in non-immune cells such as epithelium remains understudied. Respiratory epithelium is a major site of pathogen exposure, and recent studies hint at the ability for respiratory epithelial cells to undergo trained immunity. This project will provide a comprehensive analysis of trained immunity in the respiratory epithelium using a physiologically relevant in vitro model of human airway epithelium. An interdisciplinary approach will be used to characterize metabolic, epigenomic, transcriptomic, and proteomic changes associated with the trained phenotype. Functional relevance will be assessed through viral challenge experiments, and findings will be validated using clinical respiratory cell samples collected after viral infection. Altogether, this work will expand the understanding of trained immunity in barrier tissues and may reveal novel therapeutic targets for preventing and treating respiratory infections.


**Keywords:** Trained immunity;  Respiratory epithelium;  Innate immune memory; Airway infection;  Epigenomic reprograming
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fifth Framework proposal on 'Mathematics and scientific computing for technology and research'.

assistant: **Innovation**

The Eindhoven Centre for Computational Engineering (ECCE) of the Eindhoven University of Technology invites graduate students from member states or associated states of the European Union to participate in a Marie Curie training programme on Mathematics And Scientific computing for Technology and Research (MASTER). In ECCE experts in applied analysis, scientific computing and mathematical engineering are co-operating in research and education. During a six-month stay the trainee will have the opportunity to do research on one or more parts of the chain: modeling of problems from engineering, their mathematical analysis, numerical simulation and design. Besides, there will be possibilities to follow advanced courses by internationally renowned teachers. Industry needs well-trained mathematicians, who can understand and translate the problems from engineering into mathematically relevant terms, assess their complexity and know to find ways to tackle the problems. This requires a solid mathematical knowledge, an ability to understand the physics and to communicate with the engineering community. There is also a need for engineers trained in using mathematical tools and thus the tailor-made training programme will also be open to mathematically interested engineers. Fellowships are available in the following areas : mathematics of materials, combustion, porous mediaeletrical circuits, dynamics and control. The fellows will be embedded in a multidisciplinary environment, with daily contact to mathematicians, engineers and people from industry. The Eindhoven University of Technology offers excellent housing facilities for temporary guests. Ph D students who are interested to learn more about the specific subjects may consult the web (www.ecce.tue.nl/) for further details of p
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Optimizing Passenger Experience in Public Transport' (OptiPEx).

assistant: **Innovation**

The current global climate crisis and ongoing shift towards autonomous transport necessitate sustainable and passenger-centric public transport solutions. The goal of OptiPEx is to enhance of sense of comfort and safety of the passengers as well as the security and ease of travelling by co-creating ethical and passenger-aware public transport services together with specific target user groups, such as wheelchair users, passengers with large objects, fragile passengers with limited mobility, tourists and students. To achieve this, OptiPex is built on three fundamental development pillars: measurement, analytics and interaction. OptiPEx partners will develop perception technologies to measure passenger behaviour and situations. Trustworthy analytics is essential in recognising real-time passenger experiences and situations, enabling interaction with services and vehicles. Moreover, OptiPEx partners will develop adaptive and interactive vehicle technologies and digital services in collaboration with target groups and suitable for various public transport modes. These services will optimise the onboard experience, promoting safety, inclusiveness and trust. Ultimately improved passenger satisfaction will drive the adoption of automated public transport technologies and improve the sustainability of mobility services via contribution to the modal shift.A consortium consisting of 3 research organisations, 6 industry members and 2 SMEs will validate the developed solutions together with target groups and other stakeholders in three living labs. The consortium has leading expertise in human behaviour, user-centric design, vehicle technologies, modelling and data analysis, and adaptive and interactive services. The successful adoption of OptiPEx results will be facilitated by eff
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Sixth Framework proposal on 'Novel strategies for the total synthesis of bioactive macrocyclic natural products'.

assistant: **Innovation**

The synthesis of natural compounds with biological activity is one of the most important areas in organic chemistry, and also for the agrochemical and pharmaceutical industry.Polyketides are the most abundant medicinal agents among natural products. Structural diversity and wide scope of bioactivities are typical of the group. This proposal is focused upon the synthesis of resorcylate bio-active natural products and the underlying synthetic methodology.The objective of this research project is the total synthesis of two resorcylate natural products with potential bio-activity, the important anabolic, estrogenic and antibacterial macrolide zearalenone and the potent antifungal agent 15G256b (previously not synthesized), through concise and simplified bio mimetic-like routes.The methodology that will be used for the development of the synthetic route will be based on lactone macrocyclisation using enyne metathesis reaction and calcium (II) catalytic transesterification as key steps, also studying the scope o f these reactions in the synthesis of polyfunctionalised targets.The development of the project will contribute positively to my career development as a scientist, offering me the key experiences to mature and enhance my career in the future as an independent researcher.It will be beneficial for the objectives of the European Research Area because it will qualify me to develop my future career inside the European Community completing my scientist training with trans-national mobility, a strategic goal for the European Policy training objectives.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Control of fluorescence energy transfer in near-field optics', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

Experimentation and simulation of single molecule fluorescence triggered in near-field optics. A SNOM tip is used to excite a molecule in the very near-field and simulations involve a precise evaluation of both electric field and fluorescence lifetime.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'University-school partnerships for the design and implementation of research-based ICT-enhanced modules on Material properties' goes beyond current state-of-the-art under Sixth Framework.

assistant: **Innovation**

The project aims to create a mechanism for integrating the results of science education research in school teaching practice for 10-15 year olds in the domain of Properties of Materials. We propose to set up local working groups consisting of researchers and experienced science teachers with the remit to design, implement and evaluate teaching modules in the following areas: materials around us: everyday applications of metals, ceramics, plastics and composite materials; mechanical properties of composite materials; thermal insulators and their properties; electro-luminescent materials; electromagnetic properties of materials; optical properties of materials and their application in telecommunications; chemical properties of materials.The modules will utilize existing modelling and simulation tools (such as, Insight, ThermoLab, Stagecast Creator, Coach, Modelus, Virtual Laboratories) in order to achieve teaching approaches that adhere to the principles of inquiry based science, active student engagement and collaborative learning. The modules will include activity sequences and specific instruments and procedures for the evaluation of learning outcomes. Student assessment will place emphasis on the transfer of acquired knowledge and skills in contexts that were previously unfamiliar to the students.An international steering committee of experts will monitor the process and will create generic guidelines for the design and evaluation of the modules. These generic guidelines will also serve as a useful template f or exchanging examples of successful practice and transferring expertise from one educational system to another.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Neural stem cells - from basis science to cns repair' (NEUROPAIR) targeting Fifth Framework.

assistant: **Abstract**

Neurons are lost from the brain in neurodegenerative diseases like Alzheimer's and Parkinson's disease. The use of Neural Stem Cells (NSC) to replace the lost cells in the damaged brain is an exciting possibility, but our poor understanding of Sociology holds the development of Ness as potential therapeutic agents back. Here, we address crucial questions that need to be answered if stem cell therapy is to succeed. We have identified genes important for NSCs and defined stem cell populations that differ in their capacity to repair. The skills in abroad range of experimental techniques are well developed in the seven participating laboratories. Our approach is to apply this interdisciplinary expertise to clarify the significance of these genes and cell populations in Scraper. We expect to have established some of the basic parameters that determine the success of NSC transplantation as a therapy for neurodegenerative disease.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'LIdar Knowledge Europe' (LIKE), addressing dissemination and exploitation.

assistant: **Impact**

LIdar Knowledge Europe (LIKE) fosters training and education of young researchers on emerging laser-based wind measurement technologies and its translation into industrial applications. Doppler Lidars (light detection and ranging) that measured the wind in the atmosphere remotely have reduced in price and increased reliability over the last decade mainly driven by European universities and companies serving the growing wind energy industry. This opens the possibility for new applications in many areas. LIKE improves, tests and refines the technology thus expanding these areas of application. LIKE promotes wind energy applications such as wind resource mapping using scanning lidars and control of individual wind turbines or entire wind farms in order to increase energy production and reduce mechanical loads. LIKE maps unusual atmospheric flow patterns over airports in real-time and thus improves the safety of landing aircrafts. LIKE explores wind and turbulence under extreme conditions at the sites of future European bridges paving the road for optimal bridge design. LIKE trains 15 ESRs to an outstanding level at world-leading European academic institutions and industrial companies, thus forming strong interdisciplinary relations between industry and technical sciences. These relations are implemented through employment of the ESRs at academia as well as industry, and through inter-sectoral secondments. Finally, translation of technology into specific applications is emphasised through the implementation of an entrepreneurship training course involving all ESRs and LIKE partners, particularly industry.


**Keywords:** Wind energy, Atmospheric turbulence, Scanner lidar, Remote Sening
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Concerted Action Multigeneration Energy systems with Locally Integrated Applications' (CAMELIA) targeting Sixth Framework.

assistant: **Abstract**

The Coordination Action aims at leading a general survey and analysis of the various possibilities of producing electricity together with other energy (heating, cooling) from waste, biomass and other RES in a view to apply it for buildings energy supply in an autonomous way so as to reduce drastically the CO2 emissions due to energy consumption from the building sector.In this CA, we want to get an inventory of the state of the art, explore various promising cost-effective systems and analyse future implementation taking into account:- impact of innovative technologies (heat driven devices and possibly CO2 capture and storage) to reduce CO2 emissions;- people response to new systems (regarding habits, constraints and costs) environmental impact (in particular overall GHG -greenhouse gas- emission decrease) versus techno-économie aspects;- energy storage and integration of electricity surplus to the network.