RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Species-specific aspects in eukaryotic mRNA translation modulation and their implications in diseases', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

mRNA translation is a universally conserved process consisting on translating the genetic code into proteins, the primary building blocks of all living organisms. Translation is mainly operated by the ribosome, a hybrid molecule made of RNAs and proteins. In most eukaryotes, at least two types of mRNA translation coexist in nearly all cells. Indeed, although the quasi totality of the proteins is translated in the cytosol by the cytosolic ribosome, a small yet essential fraction of mRNA translation can take place in the mitochondria, the cell’s power plant. While mitochondrial translation process has proven to be substantially species-specific, numerous species-specific structural and regulatory differences also exist in the cytosolic translation process in spite of their relative conservation among eukaryotic species and are yet to be elucidated. We will use various structural and molecular biology methods to investigate, from a disease-related perspective, several species-specific aspects of mRNA translation modulation in mammals and in pathogenic parasites from the family of kinetoplastids. Namely, 1- we will investigate the molecular roles of several kinetoplastid-specific proteins involved in translation and evaluate their validity as pharmacophores. 2- We will study mitochondrial translation in kinetoplastids and focus on its variable regulation in different forms of the parasites during their life-cycle (blood vs. insect stages). 3- We will study cytosolic mRNA scanning for the start-codon during translation initiation to i) understand its molecular basis in different types of mRNAs (native and modified mRNAs, natural or artificial), ii) and investigate its alteration in colorectal cancer caused by the absence of a ribosomal RNA modification. Results will advance
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'European crayfish as keystone species-linking science, management and economics with sustainable environmental quality' (CRAYNET), addressing dissemination and exploitation.

assistant: **Impact**

Monitoring European native crayfish populations as indicators of biodiversity is an important tool in environmental management. The proposed network would emphasise knowledge-based management strategies and a common European approach to management techniques; it would also develop the links between researchers, managers and sustainable policies for development through rural agencies and regional programmes such as Interreg, Leader...As the programme is based on fundamental scientific knowledge it would be also have relevance to theme area2.2.3 Assessing and Conserving Biodiversity. The programme structure comprises two successive phases:(1) the link from science to management, as initiated during a congress in Poitiers (September 2001) and(2) further links to economic development.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Crop Monitoring as an E-agriculture tool in developing countries' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

This proposal is introduced to address the Target Outcome B" stated in the Objective ICT-2009.1, namely the support to the uptake of European ICT research results in developing economies. The objective can be realized by setting up an advanced European E-agriculture service in two developing economies, Morocco and China, by means of crop monitoring. The activities of capacity building will be carried out in the third developing country, Kenya, to raise the interest of local stakeholders on European E-agricultural practices and to pave the way for an eventual technological transfer in the future.<br/>The European research institutions including VITO, Alterra, JRC and University of Milan, have developed series of agricultural monitoring approaches to support European Common Agriculture Policy (CAP). These approaches are based on the European Information and Communication technologies including space-based Earth Observation (EO), geographical information systems and agro-meteorological modelling. The transfer, adaptation and local application of these E-agriculture practices will assist the policy makers of developing countries in their challenge to sustain agriculture's productivity growth. It helps to achieve the food security, increase farmer incomes and protect local farmer interest, in the context of agricultural liberalization, which is a fiercely disputed issue in the forums of the World Trade Organization.<br/>On the other hand, the feedback from this proposed action will enhance the applicability of European crop production forecasting technology on a global scale, thus ultimately strengthen its capacity in global monitoring of food security."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Operators training distributed real-time simulations' (OPERA) targeting Fourth Framework.

assistant: **Abstract**

The global objective of the project is to specify, develop and qualify a cost-effective simulator prototype for training of operators in the field of chemical and plastics processes.From the end-users point of view, major expected impacts of the technology shall be :the improvements of the learning process efficiency, and demonstration of cuts in training time and costs, the increase of operators productivity, the improved manufacturing performance, the enhanced safety of operations and the exhibition of the consecutive return-on-investmentsThe technology providers objectives are mainly :to address new markets, to extend current product design based on cost-effective technologies and open architecture toward distributed computing technolgoy to address performance requirements as regards to real-time requirements for training applications, and with new models and possibly new services (like openess to Internet/Intranet technologies and to supply customers with a complete set of software tools in the field of chemical process and control systems simulations.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'EMBnet ca - Europe's bioinformatics infrastructure network' (1994-1998).

assistant: **Concept**

The aim of the proposal is to maintain and further develop the European Molecular Biology Network (EMBnet), a group formed by 26 specialist centres in biotechnology. These are mandated by national science agencies to carry out the service and research oriented duties described in the statutes of the EMBnet foundation (annex 1). This concerted action project will provide coordinating activities, as well as technical, educational and promotional support for EMBnet. EMBnet primarily distributes data and offers computational access and user training on molecular databases used in biotechnology. The EMBnet nodes primary goals are to provide support at national level, distribution of databases and programs and organise training at both beginner as well as advance levels. EMBnet represents a wide European user group and works closely together with the database producers such as EMBL's European Bioinformatics Institute (EBI), The University of Geneva (Swiss-Prot), the Martinsried Institut fuer Proteinsequenzen (MIPS), in order to provide a uniform coverage of services throughout Europe. EMBnet is registered in the Netherlands as a public foundation (Stichting). Within the European Union EMBnet has 20 member institutions which are associated partners in this proposal. (All EU countries, except Luxembourg, have at least one EMBnet node). - Coordination and organization: EMBnet is governed by the Annual EMBnet Meeting (AGM), and is coordinated by an Executive Board that oversees the activities of three project committees: Education and Training E&T), Promotion and Public relations (P&R), Research and Development (R&D). - The technical support is in the form of a user help-desk and the Technical Manager project that provides assistance and practical help to the participating nodes
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Load-bearing capacity of continuous lightweight sandwich panels' will create measurable scientific, societal and economic impact aligned with Fourth Framework.

assistant: **Impact**

Research objectives and content The main objective of this research work is to develop methods of modelling the structural behaviour of continuous lightweight sandwich panels using Finite Element Method (FEM). The objective is one of the current interests of manufacturers and designers of structural sandwich panels because the design principles of continuous panels are under construction in Europe. Numerical methods are very seldom utilized in the analysis of sandwich panels in civil engineering. The computations will be used to study the influence of material properties and variations in the geometry of sandwich panel on the performance of a continuous panel. Verification of the Finite Element models will be done by comparison of the computed results with experimental results obtained in the previous research carried out in 1993-1997 in the Laboratory of Structural Mechanics at Helsinki University of Technology. Numerical results are also used to validate the analytical calculation models developed in the previous research project. The research work will be carried out 1.1.1998 - 31.12.1998 in the Institute of Lightweight Structures and Aerospace Engineering (ILFB) at Vienna University of Technology. The research infrastructure and the research focuses of the ILFB agree extremely well with this research. The ILFB has world-renowned expertise in the development and application of the numerical methods, specially the FEM, for the analysis and design of lightweight structures. The know-how and sophisticated computational techniques, which cannot be found in commercial programs, offer an unique approach to the analysis of sandwich panels used in civil engineering applications. Training content (objective, benefit and expected impact) My research work benefits strongly the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Phototransformation and photonitration processes of aromatic compounds in surface waters: environmental significance and impacts on living organisms'.

assistant: **Concept**

The Rhône river delta region and its lagoon system are located in the southern part of France, and it is a zone of great environmental importance as one of the main wintering sites for water birds in the Mediterranean area. It is also subject to a good level of environmental stress because of agricultural activities. The region is polluted by high usage of pesticides and herbicides, resulting in high concentration of aromatic and nitro-aromatic compounds (NACs). The latter are formed by photochemical reactions, are chemically stable, phytotoxic and genotoxic. Due to the significance of the Rhône delta region, it is very important to study the various photochemical pathways that are leading to the occurrence of the different pollutants in surface waters. The present study will be based, as starting point, upon the field monitoring carried out at the University of Marseille (with which the host institution is presently collaborating) on the surface water of the Rhône delta. From the time evolution data of the source compounds and their derivatives, combined with laboratory simulations of the processes involved, it will be possible to gain information concerning the relevant transformation pathways. Additionally, mutagenicity tests concerning the compounds under study will be carried out on inland water crustaceans such as the Artemia shrimps, which reproduce by parthenogenesis and, being monoclonal as a consequence, are particularly suitable for gene mapping and mutagenicity assessment. With the knowledge and experience gained during the fellowship, a similar study will be carried out within the framework of the Kolleru Lake of Andhrapradesh, India, contaminated by pesticides from the surrounding agricultural activities. The applicant will carry out this research work wit
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Electrical tomography for phase change monitoring'.

assistant: **Objectives**

Heating/cooling demands represent more than half of energy consumption in households and drive most of energy-related GHG emissions in the residential sector. To achieve decarbonisation goals heating/cooling demands must be supplied with heat pumps driven by renewable electricity. However, the mismatch between energy availability and heating/cooling demand needs to be reconciled with low-cost, efficient and flexible energy storage. Latent thermal energy storage (LTES) with phase change materials (PCMs) is becoming a key enabling technology for low-carbon heating/cooling. However, smart control of LTES systems require monitoring of the liquid fraction, which determines the total stored energy. The present research proposal, ET4PCM, aims to develop a first-of-a-kind, smart, non-invasive, versatile impedance sensor to evaluate in real-time the liquid fraction evolution of PCMs in LTES. The ET4PCM sensor will provide detailed information regarding phase distribution evolution during freezing/melting of PCMs in macrocapsules (spherical or cylindrical shells). The project planning contemplates four key tasks, which correspond to the sub-objectives: SO1) Characterization and enhancement of electrical properties of PCMs, SO2) design of the electrical sensing system, SO3) experimental implementation and validation of the proposed sensing system, and SO4) Validation of ET4PCM technology in a real LTES. The research approach involves experimental, numerical, and theoretical research activities. I, Dr. Carolina Mira-Hernández will develop the ET4PCM project under the supervision of Pr. Simone Mancin at University of Padua (UNIPD), who is renowned expert in LTES. In addition, I will spend 3 months during a secondment at the start-up COWA, where I will deploy the ET4PCM sensor in a r
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'The role of chemokines in the pathogenesis of atopic eczema' will create measurable scientific, societal and economic impact aligned with Fifth Framework.

assistant: **Impact**

Atomic dermatitis (AD) is inflammatory skin disease with a high prevalence and increasing incidence. Cherokees have recently been identified as the key players of tissue-specific immune responses. We propose to apply state of the art knowledge, techniques and a unique murine model of AD to examine the role ofchemokines and their receptors in the pathogenesis of AD. We will:I) characterizechemokines/receptors involved in disease initiation, progress and chronification.II) Functional relevance of chamomiles/receptors will be determined in vivo by means of a murine AD model utilizing neutralizing antibodies and knockout mice. Finally,III) Regulation of chamomile/receptor expression by external and intrinsic factors in AD will be explored. Results of this study will identify novel targets for the development of more selective treatments for AD with putatively less side effects and good patient compliance.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'PV en face ! Low-cost, high-quality concepts for facade integrated PV systems' (1994-1998), addressing dissemination and exploitation.

assistant: **Impact**

Objective PV en face! aims at the development of a number of facade integration design concepts, applying a design strategy with strong emphasis on low-cost, yet high-quality, building integration techniques. Although innovative mounting concepts are currently being developed for PV in tilted and flat roofs, this is not the case for PV facades, despite the good market perspectives for PV integration into facades. At the moment, PV facades still use tailor-made solutions requiring case by case engineering, installation by specialists and custom made modules. These tailor made solutions lead to high-quality, yet high-price solutions. However, high-quality though low-cost concepts are required to achieve a future breakthrough in the market for PV facades, the main reason for initiating PV en face! Approach PV en face! will treat add-on and facade integrated concepts both using different thermal properties and thus ensuring a wide spread applicability throughout the different Northern and Mediterranean European climates. PV en face! utilises an interactive design strategy, divided into four tasks: 1. Facade technology assessment Identify commonly used facade technologies throughout Europe. 2. Pre-designs and prototypes . Develop preliminary designs with emphasis on cost minimisation, standardisation, aesthetics and wide-spread applicability on European level. 3. In- and outdoor testing. Test prototypes, alter preliminary design, repeat test, set pre-design. 4. Pre-design conclusions Evaluate designs, recommend further design actions, real-scale pilot projects, market consortia, commercialisation. PV en face! pre-designs will be ready for benchmarking, commercialisation and subsequent marketing on the European level. Achievements Achievement of PV en face ! objectives will l
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Sixth Framework proposal for the project 'Low-cost 1.3um sources for FAST ACCESS technologies'.

assistant: **Objectives**

The objective of the project is to develop low-cost, 1.3um dilute nitride laser sources for use as directly-modulated transmitters in access applications. These applications require stable and reliable sources, which can be produced at very low cost and operated in an uncooled environment.Dilute nitride lasers are expected to have significant advantages over InP-based devices in terms of both cost and temperature performance. Both edge-emitting lasers (EELs) and vertical cavity surface-emitting lasers (VCSELs) will be investigated for 2.5Gb/s and 10Gb/s applications. The materials development will focus on improving the optical efficiency and stability of the novel dilute nitride materials, exploring the use of growth chemistry and advanced composition-, bandgap- and strain-engineered active regions.The epitaxial growth activities will exploit highly developed growth techniques and sophisticated epi-layer structures to enhance device performances while limiting the cost. The device processing activities will investigate advanced surface microstructures to boost the device performances, reduce the number of optical components and lower the packaging complexity. All device development activities will be supported by device modelling activities. The design activity will aim for suitable thermal, dynamic and modal performances and will examine large-signal modulation effects. Optimised VCSELs and EELs will be packaged and characterised.The cost, performance and reliability of these devices will be compared with that of state-of-the art 1.3um InP-based EELs (optimised for access applications), both for current 1.0-2.5Gb/s applications and for emerging 10Gb/s applications. The direct digital modulation performance of these devices will be evaluated and standard network modell