RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Sixth Framework proposal for the project 'Evolutionary reproductive ecology of caecilian amphibians'.

assistant: **Objectives**

Caecilian amphibians are burrowing predators of tropical soil ecosystems. They have exceptionally diverse reproductive modes (e.g. oviparity, viviparity). The project is an integrative analysis of the evolution of this reproductive diversity. We hypothesise a linear sequence of evolutionary changes between reproductive modes, the extent and form of investment in propagule size and quality, and regimes of parental care. We will test the hypothesised evolutionary changes by integrating data on different modes in a comparative phylogenetic context. We also aim to test the 'skin feeding hypothesis for the function of the enigmatic 'foetal' teeth' recently discovered in oviparous caecilians. A broad range of classical and modern methods will be used in an innovative combination of detailed laboratory and field study designed to directly test explicit hypotheses. Morphological data on foetal teeth will be generated with SEM (Scanning Electron Microscopy), histology and cleared and stained specimens. At field sites in Tanzania and French Guyana direct observations of parental-offspring interactions will be made. Morphometric data will be recorded in the field and also from preserved material. Molecular systematics will be applied to place new species studied in this research intophylogenetic context and further to check the association of different life history stages. Multivariate statistical analysis is used to test the predicted correlations of maternal traits. The main outcome will be an understanding of the pattern of evolution of reproductive modes with implications for the use of caecilians as a model system for studying the evolution of tetrapodterrestriality and the origin of amniotes. Additional major outcomes include, provision of baseline data on the life historie
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Challenging the Liberal World Order from Within: The Invisible History of the United Nations and the Global South' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Of the 193 member states of the United Nations (UN), over half belong to the grouping known as the Global South (also called the Developing World or Third World). Since its creation in 1945, Global South actors have sought to redefine political dynamics and change normative practices through the UN. Yet, histories of the organization are predominantly from the Western perspective. Challenging this view, this research will make a ground-breaking contribution to the field, providing a new genealogy of the UN within the contextual frame of global history in order to investigate how Global South actors shaped global order. It will bring together different perspectives of the UN from archives across the Global South, revealing currently invisible histories of the organization by examining how it was developed by Global South actors between 1945-1981. The project has 3 closely related objectives: 1. To examine how actors from the Global South changed the UN by developing its functions in the areas of decolonization, economic development and human rights; 2. To trace the ways in which Global South actors challenged the liberal world order as they pursued these rights; 3. To analyze why Global South agency at the UN led to the promotion of some issues and actors and excluded others and ask what the consequences were for order within the Global South. The projects innovative contribution is in explaining the ways in which the UN has changed over time by placing an emphasis on the dynamic role of Global South actors. The research will elucidate histories of the ordering role of institutions at a moment when global governance is in crisis and the liberal world order appears to be fragmenting. Its primary impact will be in decolonizing the historiography by highlighting the histori
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Spatio-temporal regulation of viral-induced innate immune response in intestinal epithelial cells'.

assistant: **Concept**

Intestinal epithelial cells (IECs) constitute the primary barrier that enteric pathogens have to face. The mechanism by which innate immunity is regulated in IECs remains unclear. However, it is known that a delicate balance is required to efficiently recognize pathogens and at the same time to not illicit an immune response against the commensal microbial flora. Inappropriate immune response to the commensal flora is suspected to be responsible for inflammatory bowel diseases.We found that IECs could generate a different innate immune response upon viral infection, depending on where the infection originates from (apical vs. basolateral). Moreover, infection of the cells from the apical plasma membrane (gut lumen) renders IECs less responsive to subsequent viral infection. This down-regulation of innate immune response could represent a mechanism developed by IECs to avoid recognition of the commensal flora thereby preventing constant inflammation of the bowel.The objective of this project is to discover the means by which antiviral innate immunity is achieved and regulated in IECs. We will use a multidisciplinary approach, combining live-cell microscopy, single particle/molecule tracking, biochemistry, and genomics. The specific aims are:1) Determine the importance of RLR and TLR in generating an innate immune response in IECsWe will characterize the signaling pathways triggered upon viral infection of IECs from the apical and basolateral sides. We will characterize the mechanism by which apical infection downregulates the innate immune response of subsequent infection.2) Spatio-temporal aspect of viral RNA recognition in IECsWe will develop new tools to study, within a living cell, the spatio-temporal aspect of virus detection by the cellular sensors RLR and TLR. We
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Spatial Integration in Cell Cytoskeleton' in the context of a Seventh Framework call.

assistant: **Objectives**

The functional coherence in multicellular arrangements depends on each cell’s ability to adapt its internal organisation to the spatial configuration of their microenvironment. The asymmetric distributions of cell compartments and peripheral domains define the cell polarity. In multicellular animals, the establishment of cell polarity is mainly regulated by the cell’s adhesions to its neighbours and to the surrounding extracellular matrix (ECM). How cells integrate all these cues in space and time to determine the orientation of their polarity is a fundamental but unresolved problem.I hypothesize that the centrosome, which regulates the radial organisation of microtubules throughout the cell, plays a major role in the spatial integration of peripheral adhesive cues. Each type of adhesion induces the assembly of actin filaments into defined dynamic architectures. These architectures produce specific mechanical forces on microtubules. The net force displaces the centrosome-microtubule network and thereby repositions cell compartments and orients cell polarity.I propose to develop a new experimental strategy to manipulate cell adhesions in space and time. Using surface micropatterning and a new laser activation method, the spatial organisation of cell-cell and cell-ECM adhesions in complex multicellular context will be manipulated in real-time. We will quantify the dynamic rearrangements of actin and microtubule networks and measure intracellular forces. These results will allow us to develop a new physical model describing the stability of cell polarisation states. Finally, in the context of this model, we will explore the contribution of polarity reversal to critical morphogenetic events.This work will demonstrate that cell polarisation is a dynamic and mechanical event
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Changing maize grain development to provide lines better adapted to the european agricultural and commercial environment' (MAZE), addressing dissemination and exploitation.

assistant: **Impact**

The predominance of American companies in corn breeding/biotechnology means that current maize lines are frequently ill adapted to the needs of European agriculture and industry. Further, European companies are badly positioned to generate and exploit know-how and intellectual property relating to this important world crop. In a radically different approach to cereal improvement, 6 world-class research groups have combined with a major industrial player to develop and exploit a range of novel technologies aimed at modifying the functional domains of the maize grain. Cellular, molecular and genetic strategies will be combined with new technologies (e.g. imprinting screens, in vitrofertilization) to reveal the molecular mechanisms controlling development of grain components responsible for the translocation, storage and processing of the major seed reserves. The industrial partner will use these data to reconstruct' the maize seed to provide new lines with improved quality and yield, better suited to the European agricultural and commercial environment. The intellectual property and know-how generated by this work, which will be applicable to all grain cereals, will do much to improve the competitive position of European breeding/biotech companies."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'New product design and engineering technologies based on next generation computed tomography' goes beyond current state-of-the-art under Sixth Framework.

assistant: **Innovation**

In a knowledge-based and customer-driven economy, it becomes increasingly important to integrate high-technology into complex goods and services which are geared towards individual user requirements. In future, the competitiveness depends on how fast and how flexible new products can be launched onto the market. Therefore new, efficient, user- and eco-friendly product design and engineering technologies are urgently required. The new approach is to base the necessary virtual models on volumetric Compute rised Tomography (3D-CT) data. The availability of 3D-CT data at different steps of the product development process allows not only high quality surface modelling or geometrical inspection but also the analysis of flaws, material inhomogeneity or material structures and helps to optimise the manufacturing parameters especially for new materials. The main project objectives are to develop new basic hardware components and algorithms for fast and accurate 3D-CT scanning for parts of any complexity and lar ge dimensions, new algorithms for automated CT image processing, fast surface and solid modelling as well as methodologies for the integration of the new technologies into the rapid product development and manufacturing process. A next generation CT prot otype will be set up for validation and testing. A particular attention will also be given to make these new technologies well known to the European key industries. Whereas the state-of-the-art CT technique is mainly originated in the U.S. the consortium has the potential to launch a breakthrough on volumetric high energy CT. The involved software companies are key players for CT image processing and metrology. The end users ensure that the new technologies meet the needs of the industry.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Development of procedures for overall performance evaluation of hybrid photovoltaic building components' demonstrating excellence, impact and implementation quality for a Fourth Framework call.

assistant: **Abstract**

Objectives Hybrid Photovoltaic components are building elements in which the PV elements produce electricity and the heating of the elements is used for other purposes. The key objective of this project is to develop a standard scheme for the performance evaluation of hybrid PV building components. Emphasis will be given to the assessment of thermal and electrical performance of these elements; other aspects, such as maintenance, durability, air and water tightness, ventilation, daylighting, will also be covered. Technical Approach The project is organised through 4 Task Areas: Task 1: Development of a performance evaluation scheme for hybrid PV components, in collaboration with industry Task 2: Further refinement of electrical performance evaluation procedures of hybrid PV components Task 3: Development of standardised test procedures for thermal performance evaluation of hybrid PV components Task 4: Modelling: Development of concept for scaling and replication of results on hybrid PV components For the experimental work, a reference component will be developed. The reference component will be subject to intensive and parallel testing at various test sites spread over Europe to assess the repeatability of the performance and the climate dependency. The test results will calibrate a simulation model. Close collaboration with industry will be set up to shape the procedures to the needs of the market. This will be organised through a seminars and the publication of a quarterly newsletter. Expected Achievements and Exploitation The output of the project includes the following deliverables: Well documented protocols for the global performance evaluation of hybrid PV components as well as their application in a certain building for a given climate.  A protocol for the assess
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Self-Configurable Cognitive Video Supervision' (SCOVIS), addressing dissemination and exploitation.

assistant: **Impact**

SCOVIS will investigate weakly supervised learning algorithms and self-adaptation strategies for analysis of visually observable procedures. SCOVIS research directly affects ease of deployment and minimises effort of operation of monitoring systems and is unique in the sense that it links object learning using low-level object descriptors and procedure learning with adaptation mechanisms and active camera network coordination. SCOVIS advocates a synergistic approach that combines largely unsupervised learning and model evolution in a bootstrapping process; it involves continuous learning from visual content in order to enrich the models and, inversely, the direct use of these models to enhance the extraction. In the SCOVIS application scenario user interaction will be significantly reduced compared to current methods. The system will be able to calculate the camera spatial relations automatically (self-configuration) for coupled, uncoupled and active cameras. The user will define a set of objects and procedures of interest during a very short supervised learning phase, while the associations with low-level descriptors will be automatically learnt. The resulting models will be significantly enhanced through online data acquisition and unsupervised learning (adaptation). The enhanced models will be able to be verified and potentially adapted through relevance feedback. The main measurable objective of SCOVIS will be to significantly improve the versatility and the performance of current monitoring systems. The resulting technology will enable the easy installation of intelligent supervision systems, which has not been possible so far, due to the prohibitively high manual effort and the inability to model complex visual processes. The produced technology will be evaluated
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Future Circular Collider Innovation Study'.

assistant: **Innovation**

What is the Origin of Everything? The Standard Model of Particle Physics explains everything except for the parts that it does not cover. This limitation calls for a science mission to gain a deeper understanding of matter, energy and the fundamental laws of nature. The first step is to elucidate the mysteries that revolve around the Higgs boson. Is it point like? Does it interact with itself? The best way to answer these such questions is to create a clean experimental environment with a highest luminosity particle collider. The Future Circular Collider Innovation Study (FCCIS) will deliver a conceptual design and an implementation plan for a new research infrastructure, consisting of a 100 km long, circular tunnel and a dozen surface sites. It will initially host an electron-positron particle collider. With an energy frontier hadron collider as a second step, it can serve a world-wide community through the end of the 21st century. This project will validate the key performance enablers at particle accelerators. Extreme luminosities, a factory producing a million Higgs bosons, luminosities up to 100 times the present world record with parts-per-million energy precision will strengthen Europe’s leadership in excellent science for many decades. This project will attract academic and industrial leaders to develop a feasible and affordable project that incorporates ecodesign and resource efficiency from an early stage onwards. The project includes work with the host states France and Switzerland to ensure that the infrastructure blends in with the territorial boundary conditions. A socio-economic impact analysis will reveal the added value that this infrastructure will generate during its first phase and serve as the basis for developing a funding and implementation plan.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'The spatio-temporal representational architecture of memory' (STREAM) under Horizon 2020.

assistant: **Objectives**

Episodic memories are the essential building blocks of our identities. How the brain codes these memories such that we can access them minutes, days or even years later is still unknown. We tend to believe that the memories we bring back to mind are more or less precise ""snapshots"" of a past event. Reflecting this view, current neurocognitive studies focus on isolating static snapshots of past events in an individual's pattern of brain activity. This snapshot approach, however, ignores the reconstructive and dynamic nature of the retrieval process, necessarily limiting our understanding of human memory. The vision behind STREAM is to advance the field beyond its current state of the art by mapping the spatiotemporal dynamics of mnemonic reconstruction in the human brain. The research programme contains three work packages that support this vision at multiple levels of investigation, from combined electrophysiological and hemodynamic activity down to neuronal assembly firing patterns in the human hippocampus. These techniques are used in combination with paradigms that decompose memories into their constituent elements, and track the neural representations of these elements as they unfold in time and space when an event is reconstructed from memory. So far, it has been difficult to integrate information obtained by these various recording techniques. STREAM will use an innovative representational mapping approach that combines spatiotemporal information at the level of an individual's neural representational architecture. This approach enables us to directly map memory patterns emerging at a given time point onto a given brain region. If successful, STREAM will reveal the first comprehensive spatiotemporal map of memory retrieval, with the potential to cause a major sh