RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'ENhanced PhD Fellowship Programme in the Sciences of LIGHT'.

assistant: **Innovation**

ENLIGHTEN is a 65-month MCSA COFUND doctoral fellowship programme that aims at recruiting outstanding  early stage researchers (ESRs) to carry out ambitious PhD-projects at ICFO in a wide range of topics at the forefront of the photonic sciences. It will offer 20 highly competitive fellowships of 36 months duration, through 4 calls, to outstanding international candidates, and equip them unique capabilities to become future leaders in the academic and industrial worlds.The objective of ENLIGHTEN is to establish a top-level European PhD program at ICFO-Barcelona, competitive with the best PhD programs in Photonic Sciences worldwide. The support provided by ENLIGHTEN will enable ICFO to continue to enhance the quality and impact of our PhD program with respect to recruitment, training, mentoring and career development. The project aims to:- Provide exceptional training to outstanding international Early-Stage Researchers in the Photonic Sciences- Embed a commitment to Open Science, Scientific Ethics, and the principles of Responsible Research and Innovation- Establish an international benchmark in supervision, mentoring and career development of ESRs- Ensure equal opportunity in the recruitment and training of ESRs from under-represented and diverse international backgrounds, with particular attention paid to women in science.ENLIGHTEN will accelerate the career development of its Fellows, and enhance the European talent base and competitiveness in R&I, strengthen research output and impact in photonic scinece, and enhance key regional and international networks of academic and industrial collaborators. ENLIGHTEN will forge a new generation of leaders with outstanding research skills, a deep commitment the highest professional and scientific standards, and a life-long con
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'A simple, repeatable way to completely remove a clot from the brain in one pass'.

assistant: **Concept**

Stroke is the third most common cause of death globally and is the leading cause of adult physical disability. Globally, seventeen million people had a stroke in 20152. Of these, 33% died and 33% were permanently disabled. A stroke occurs when a blood vessel in the brain is blocked by a clot, preventing blood flow, and causing brain damage. Stroke is a devastating disease.Perfuze has developed aspiration catheter technology intended to ingest the clot in a single attempt. No accessory devices or sophisticated techniques are required, meaning the procedure can be performed by a single operator. This maximises the chance of complete clot ingestion within the occluded vessel, complete flow restoration and improved patient outcomes. Multiple iterations have been required to reach the existing Millipede design. Pilot manufacturing lines utilising customised coiling andwire forming equipment have been built. Component and assembly drawings and specifications have been defined. Six preclinical animal studies have been performed to compliment proof-of-concept bench testing.The potential market opportunity is huge. In the US and EU alone, it is valued at $2.5bn in 2018. The Perfuze platform is uniquely positioned to exploit the recent, dramatic clinical shift away from medical therapy to endovascular device treatment of ischemic stroke.This SME Instrument Phase 2 will enable company scale up and creation of 52 jobs by 2024 and will generate over €17m in turnover.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Responsible Link-Recommendations in Dynamic Environments'.

assistant: **Innovation**

This proposal aims to develop, for the first time, new computational models to systematically evaluate 1) the long-term societal impacts of link-recommendation algorithms in online social networks and 2) design a new paradigm of link-recommenders that incentivize cooperation, collective action, and misinformation control.It is urgent to understand how algorithms used in online social media impact human behavioural dynamics given the widespread use of social media platforms and the evidence that they contribute to exacerbate radicalization, misinformation, and incite hate. This is a challenging endeavour. Online platforms are nowadays complex ecosystems where millions of humans influence each other while co-existing with AI algorithms. In this context, link-recommendation algorithms, used to recommend new connections to users, are ubiquitous. Such algorithms fundamentally affect how new connections are formed and the information users are exposed to. Governing online social networks requires understanding the impact of link-recommenders and how to adapt them to ensure long-term benefits.With RE-LINK, I aim to develop a new class of models to understand the impact of link-recommendations on social dynamics and, in turn, design a new paradigm of algorithms that balance short-term performance and long-term societal benefits. This will be achieved by developing agent-based models where the evolution of behaviours occurs over adaptive networks whose growth, in turn, follows the heuristics used by link-recommenders. I will resort to evolutionary game theory and stochastic population dynamics to formally study the stability of behaviours in this setting. I will use the modelling results to design new link-recommenders that contribute to stabilize positive social behaviours such
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Scalable Hybrid Variability for Distributed Evolving Software Systems' (HyVar) under Horizon 2020.

assistant: **Objectives**

HyVar proposes a development framework for continuous and individualized evolution of distributed software applications running on remote devices in heterogeneous environments. The framework will combine variability modeling from software product lines with formal methods and software upgrades, and be integrated in existing software development processes. HyVar's objectives are (O1) to develop a Domain Specific Variability Language (DSVL) and tool chain to support software variability for such applications; (O2) to develop a cloud infrastructure that exploits software variability as described in the DSVL to track the software configurations deployed on remote devices and to enable (i) the collection of data from the devices to monitor their behavior; and (ii) secure and efficient customized updates; (O3) to develop a technology for over-the-air updates of distributed applications which enables continuous software evolution after deployment on complex remote devices that incorporate a system of systems; and (O4) to test HyVar's approach as described in the above objectives in an industry-led demonstrator to assess in quantifiable ways its benefits. HyVar goes beyond the state-of-the-art by proposing hybrid variability;  i.e., the automatic generation and deployment of software updates combines the variability model  describing  possible software configurations  with sensor data collected from the device. HyVar's scalable cloud infrastructure will elastically support monitoring and customization for numerous application instances. Software analysis will exploit the structure of the variability models. Upgrades will be seamless and sufficiently nonintrusive to enhance the user quality experience, without compromising the robustness, reliability and resilience of the distri
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Adaptive and Trusted Ambient Ecologies'.

assistant: **Innovation**

ATRACO considers ambient ecologies consisting of people, context-aware artefacts and digital commodities (e.g., services and content). Members of the ecology are able to adapt to each other and form trusted ad hoc collaborations to achieve specific goals resulting from the need to serve specific human activities. The aim of this proposal is to research the factors and develop the technologies that will lead to the realisation of such ecologies (ATRACOs), following an interdisciplinary effort which involves Computer Science, HCI, AI, Control Theory and Sociology. Key factors of the ATRACO problem space that will be examined include adaptation, interoperability, context awareness, user interaction and dynamicity of trust. We will focus our efforts on seeking abstractions and mechanisms to mark the digital boundaries of ATRACOs for establishing trust relationships between its members, based on the concepts of digital territory and bubble, and to devise adaptation mechanisms based on supervisory control theory of discrete event systems and type-2 fuzzy logic. The project objectives are:<br/>.To understand the structure, principles and dynamics of the ATRACO problem space and to develop a conceptual framework consisting of a set of concepts implemented as an ontology, a novel interaction metaphor, implemented as a language and a layered architecture implemented with a set of components.<br/>. To research and implement the adaptation mechanisms and privacy policies, as part of the component platform. Adaptation will be provided in terms of artefact operation, ecology composition, network selection and man-machine interaction with respect to user context and behaviour.<br/>. To validate the results of our research by developing an integrated application testbed. We will experi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Heterologous immunity to Epstein-Barr virus: dissecting the role of cross-reactive CD8 T cells in mediating disease outcome in children, young adults and the elderly'.

assistant: **Objectives**

Viral infections, and the associated tumors and disease that they cause, are a major source of economic and social burden in Europe. There is an urgent need to understand the basic mechanisms behind their pathogenesis to accelerate the rational design of vaccines and therapeutics. The training of highly skilled immunologists is vital to support this process. Epstein-Barr virus (EBV) is a medically important infection, responsible for a diverse range of severe pathologies, including acute infectious mononucleosis (AIM), head and neck cancers and immuno-proliferative disorders. Cross-reactive memory T cells have recently been found to play a role in mediating EBV-induced AIM. This proposal aims to systematically dissect the mechanisms of CD8 T cell cross-reactivity in children, young adults and the elderly using EBV as an example of viral infection in humans. Using a combination of novel and sophisticated molecular and cellular techniques, these studies will 1) examine the role of T cell cross-reactivity in the development of clonal dominance patterns, 2) identify novel cross-reactive ligands, 3) characterize the functional and phenotypic characteristics of cross-reactive CD8 T cells, and 4) determine the binding kinetics of cross-reactive T cells with various ligands. It is highly likely that these cross reactive T cell responses to EBV only begin to scratch the surface of the prevalence and potential impact of heterologous immunity on vaccines and immunopathology. This training will be carried out in the Selin laboratory that has pioneered the field of heterologous immunity, and in the Price laboratory that has developed unique tools to probe the molecular mechanisms behind these phenomena. This training will provide a solid foundation for the long-term career developme
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fifth Framework proposal on 'The role of rak kinases in malignant transformation in vivo and in vitro.'.

assistant: **Concept**

Ample evidence suggests that the cryptozoic kinesis Raff-1 and B-Raff are key players in regulated and deregulated proliferation. I plan to use conventional and conditional gene ablation to study the role(s) of these molecules in established transformation models in vivo and in vitro.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fifth Framework proposal for the project 'Studies on superplastic forming technology of aluminum alloys and its automotive application'.

assistant: **Objectives**

The main objective is to gain access to know- how and expertise in super plastic forming (SPF) technology developed by Beijing Research Institute of Mechanical and Electrical Technologies (BRIMET). This technology could be of great importance for EU industries in the coming years. In the field of super plastic forming, the research in EU countries is particularly weak. This is because that although some EU institutes dedicated substantial efforts in the 1970s and 1980s, the research activities were gradually reduced due to lack of interests of industries. The most recent advances achieved in us and China makes commercial application of SPF technology promising. The expected final result is introduction of SPF of A1 alloys to automotive industry for building light car body with lower costs and shorter Time-To-Market.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'The History Play and the British Enlightenment, 1750-1815' to be submitted under Horizon 2020.

assistant: **Abstract**

The aim of this Fellowship is for the researcher, Dr David O’Shaughnessy, to develop the professional prowess, advanced training, high-impact dissemination, and practical experience commensurate with a leading independent researcher in the EU. The researcher will be based for 15 months at the Huntington Library, California (HL) supervised by Professor Kevin Gilmartin and for 12 months at the School of English, Trinity College Dublin (TCD) supervised by Dr Aileen Douglas. Research training will be implemented through an interdisciplinary project investigating the importance of the history play to the discussion and dissemination of Enlightenment ideas in the two main London theatres of the eighteenth century, Covent Garden and Drury Lane, 1750-1815. The key output will be the first monograph to be written on the eighteenth-century history play but the project will also communicate knowledge to a public audience through appropriate activities. On the outgoing phase of the Fellowship, the researcher will access expertise, advanced training, mentoring as well as having access to the Larpent Collection of theatre manuscripts at the HL, the most important archive in the world for the study of eighteenth-century theatre. Due to its unique archive holdings, the HL is the only institution in the world that can host this project; it also has collaborative relationships with Caltech and the University of Southern California (USC) which will benefit the research in significant ways. In TCD the researcher will be given the opportunity to embed his new knowledge through undergraduate and postgraduate teaching, conferences and a symposium, and continued research.  The resources of the host institutions will facilitate development of an interdisciplinary and international academic netw
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Speedmeter: Quantum back-action noise-free interferometry for improving the science capabilities of future gravitational wave observatories'.

assistant: **Innovation**

The discoveries enabled by observations of gravitational waves (GW) from merging black holes and neutron stars provided us with a stunning glimpse of the immense potential of GW multi-messenger astronomy and cosmology. In order to discover new phenomena and better understand the constituents of the Universe and the forces driving it, it is vital to improve the sensitivity of future GW observatories. Indeed, to maximise the observation capacity of future GW observatories such as the Einstein Telescope (ET) it is imperative to go beyond the current quantum noise limit imposed by the uncertainty relation originating from a continuous position measurement of the interferometer mirrors, i.e. [x(t),x(t')]≠0. Quantum mechanics provides speedmeter interferometers (SMI) as a more elegant approach: measuring momentum (speed) of the test masses evades the uncertainty limit, i.e. [p(t),p(t')]=0. However, though SMI have been shown theoretically to offer superior sensitivity compared to currently used Michelson interferometers with squeezed light injection, the SMI concept lags behind in technical readiness and hence is currently not yet considered mature enough to build the baseline for ET.This grant will enable me to change this. In particular I will focus on two novel SMI concepts, we invented and which (in contrast to earlier SMI concepts) are easily implementable into current long-baseline interferometers. The main objectives of this proposal are: 1) development of the required new optical components and quantum noise analysis tools; 2) experimental demonstration, initially in proof-of-concept table-top experiments, followed by implementation in ETpathfinder, a unique cryogenic interferometer test facility; 3) verification of the SMI concept with complementary quantum technolog
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Articular cartilage regeneration through the recruitment of bone marrow derived mesenchymal stem cells into extracelluar matrix derived scaffolds anchored by 3D printed polymeric supports' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Osteoarthritis (OA), the most common form of arthritis, is a serious disease of the joints affecting nearly 10% of the population worldwide. The onset of OA has been associated with defects to articular cartilage that lines the bones of synovial joints. Current strategies to treat articular cartilage defects are ineffective and/or prohibitively expensive. The aim of ANCHOR is to develop and commercialise a new medicinal product for articular cartilage regeneration that recruits endogenous bone marrow derived stem cells into an extracellular matrix derived scaffold anchored to the subchondral bone by 3D printed polymeric supports. By recruiting endogenous cells into a supporting scaffold, ANCHOR will obviate the need for pre-seeding scaffolds with cells prior to implantation into cartilage defects, thereby dramatically reducing the cost and complexity of the repair procedure. It will also overcome the need for suturing of a scaffold into a cartilage defect, which is a very time consuming and technically challenging surgical procedure. Finally, the inherent chondro-inductivity of the cartilage ECM derived scaffolds developed by the applicant will maximise the potential for hyaline cartilage regeneration. The project will leverage the applicants extensive experience in ECM derived biomaterials and 3D printing to develop a new product with significant commercial potential. The impact of ANCHOR will be multi-faceted:  it will transform how damaged joints are treated by orthopaedic surgeons, it will create economic value through the commercialization of IP, and most importantly it will improve patient experience and their long-term health and well-being.