RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'An integrated strategy for the conservation and use of underutilized Latin American agrobiodiversity'.

assistant: **Innovation**

LATINCROP objectives are to reinforce agrobiodiversity conservation in the Andean region; to identify promising underutilized species for commercial initiatives and improved food security; and to integrate activities into a strong network between relevant stakeholders in Latin America and the EU. The project will identify attractive species for marginal lands involving novel crop combinations thus establishing robust cropping systems. The underutilized species of the Andes are regarded as extremely nutritious and stress tolerant, hence significant components of human culture at present and in the future, with a vital role in the upkeep of sustainable livelihoods and ecosystem stability. Yet, the loss of species, cultivars and wild relatives, and associated traditional knowledge at the farm level, has a noticeable impact on food security of small hold farming communities and their ability to cope with adverse climates. LATINCROP will address the following themes: (A) Environmental - Conservation of agro-biodiversity, (B) Economic - Sustainable development of bio-economy, (C) Social - Improved food security, and (D) Network - Supporting existing activities into network. The project duration is 48 months to be implemented by a team from Bolivia, Peru, Ecuador, Denmark, UK and Spain. The project takes stock of related past and on-going projects and will complement them in an integrative approach to obtain long-term results leading to increased food security, on the selected crops among seed, roots and tubers. The principal expected outcome is the strengthening of the conservation of the Andean agrobiodiversity for food security and global bioeconomy. We will improve sustainable use of agrobiodiversity by developing underutilized crops, supporting economic development in Lat
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Identifying best practices for care-dependent elderly by Benchmarking Costs and outcomes of community care' under Seventh Framework.

assistant: **Concept**

Problem:The need for cost effective health systems in Europe is imperative in the context of an increasing demand for health care by growing numbers of elderly people and a shrinking working force. Many health care systems are changing and looking for mechanisms to ensure, measure and improve the quality of care. On the other hand it is unclear which models of care delivery are the most cost-effective. To enable lower public spending and advance the economic efficiency of community care organisations policymakers need information on which type of community care delivery provides best outcomes against reasonable costs.Aim:To identify best practices in community care delivery for dependent elderly, by benchmarking the cost-effectiveness of health care systems, taking into account costs of care, quality of care and organisation of European community care organisations.(Expected) results:IBenC capitalises on a standardised instrument, the Resident Assessment Instrument for Home Care (interRAI-HC), which is used in routine care provisioning to assess patient outcomes, care use and quality of care. Building on existing data from the former FP5 project AdHOC (n=4010) and new data collection (n≥2750) a novel method to benchmark community care organisations will be developed: quality and cost of community care will be compared into one measure. Based on the interRAI-HC a summary measure for organisation performance, based on quality indicators, will be developed and the interRAI-HC will be validated for costs of care assessments from a societal perspective. To enable an in-depth interpretation of best performing practices, the contexts and characteristics of community care organisations will be studied rigorously.IBenC will actively contribute to public health by enabling longer
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Helicopter Deploy GNSS in Europe – NEXT'.

assistant: **Objectives**

HEDGE Next is framed as follow up of activities initiated under previous HEDGE activity. This new project phase aims at completing the operational implementation of EGNOS operations into the rotorcraft domain, by supporting the certification of vehicles and validation of EGNOS enhanced operations from different operators spread over Europe.HEDGE Next in addition includes an important part on R&D, towards the full exploitation of EGNOS services into the rotorcraft sector. Those initiatives are either identified and recommended to pursue during the first phase of the activity, or upcoming from parallel activities participated by the Consortia leader under Clean Sky framework, and as such endorsed by Eurocopter and Augusta Westland R&D strategy.More precisely HEDGE Next will target the following objectives:§   To operationally implement Rotorcraft EGNOS APV (Approach with Vertical Guidance) in the selected sites in Spain, Poland and Switzerland.§   To achieve the certification of different helicopters models based on the abovementioned sites (potential users of instrument flight procedures based on GNSS).§   To create low-level RNAV routes that intercept the SOAP (SBAS Offshore Approach Procedure) procedure in the North Sea§   To move forward on the development, test and validation of curved approaches for rotorcraft helicopters using GPS and SBAS as sensor: PinS RNP-AR concept§   To develop a “e-VFR” navigation module in order to enhance the navigation of helicopters in marginal VFR conditionsThe proposed activities are well endorsed and aligned with the main European rotorcraft manufacturers and operators strategies, towards the full implementation of GNSS based operations, and in particular enhanced by EGNOS. The work performed on HEDGE Next shall contribute to the futu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Antiviral activity of hsv-1 glyooproteins synthetic peptides' will create measurable scientific, societal and economic impact aligned with Fifth Framework.

assistant: **Impact**

The research proposal foresees the development of new molecular entities based on synthetic peptides and peptidomimetics able to target with high affinity and selectivity receptor and functional sites in the Herpes simplex virus type 1 (HSV-1) lipoproteins, to be used as antiviral compounds in treatment of HSV-1 infections and as tolls to understand the molecular mechanisms of HSV-1 entry. In particular the novel molecules will be developed to target lipoprotein H (go), B (gab), D (god)and L (gel) functional domains of the HSV-1 in order to reduce or abolish virus infectivity. The research goal will be reached through design, synthesis and in vitro and vivo testing of the new molecules.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Impact of gut microbiota targeted dietary intervention  on obesity: A precision medicine approach'.

assistant: **Concept**

The main objective is to analyze the impact of dietary hypocaloric interventions based on their capacity to generate ketone bodies in different degrees of intensity: using Intermittent fasting, KetoDiet in comparison with the classical MedDiet, in individuals with obesity, and their influences on the gut microbiota, resistome, host metabolism, and the possible genetic and epigenetics links. We aim to contribute with the advance in the development of a precision medicine approach in obesity to decrease the prevalence of obesity and its associated comorbidities, and to evaluate the impact of dietary interventions as an alternative approach to antimicrobial resistance.To achieve our goal, we will study in a randomized cross-over group of individuals with obesity: A) Analyse the effect of dietary interventions (MedDiet, intermittent fasting (IF) and KetoDiet) on the gut microbiota composition and the relationship with anthropometrics, metabolic, inflammatory and epigenetics driven factors at short term (1 month) B) Analyse the effect of dietary interventions (MedDiet, IF, KetoDiet) on the gut microbiota composition and the relationship with epigenetics factors at medium-term(3 months) C) Evaluate the impact of the gut microbiota targeted dietary interventions (MedDiet, IF and KetoDiet) at short- and medium-term on the gut resistome and relate it with the inflammatory milieu of the host.Our results will help to improve the treatment of metabolic diseases associated to obesity using a precision medicine approach based on the influence of diet interventions on the gut microbiota, gut resistome, host response and environmental factors. The outcome of this project will have an impact in the health sector by improving mental health and physical health of all overweight and obese
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Mechanism and functional consequences of Streptococcus pneumoniae chromatin remodeling of epithelial tissue' to be submitted under Horizon Europe.

assistant: **Abstract**

Streptococcus pneumoniae is a pathobiont that is a top 10 WHO priority pathogen. Whilst it is commonly carried in the nasal cavity of healthy populations, it also causes invasive disease in vulnerable populations causing pneumoniae, meningitis, and septicaemia. However, the host factors involved in maintaining colonisation or triggering an immune response are currently unknown, and my research project aims to address this knowledge gap. In line with the expertise of the Hamon lab, the project will focus on bacteria-induced histone modifications which corelate with altered host gene expression. Following on the discovery that a colonising and asymptomatic strain of S. pneumoniae activates the histone demethylase KDM6B for immune homeostasis, the project will characterise the KDM6B-mediated response at the molecular level in a physiological model of nasal epithelium. Specifically, the research objectives are to:1) Identify KDM6B binding partners during S. pneumoniae challenge2) Define the nasal tissue response to S. pneumoniae3) Characterize the KDM6B-mediated nasal tissue response to the bacteriaThe host laboratory has a powerful model of reconstituted nasal epithelium model in which responses to a colonising or an invasive strain of S. pneumoniae can be evaluated. I will use and gain expertise in cutting edge techniques such as mass spectrometry to determine KDM6B binding partners and single-cell RNA sequencing along with spatial transcriptomic technology (MERFISH) to analyse host cell responses at the single cell level. The field of bacteria mediated histone modifications is in its infancy and offers a large margin of discovery. Altogether this project will advance our understanding of the signals and pathways that regulate the balance between homeostasis and infection
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Computer-Aided Design Of Revolutionary Superalloys' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Metallic alloys are used in many industrial applications, needing the constant development of new materials with tailored properties. However, the relations between composition, processing and properties are so complex that alloy development cannot be made anymore by a traditional trial-and-test procedure, and there is a growing need for models able to predict the behaviour of alloys as a function of composition, and for computer-aided optimisation tools for alloy design. The aim of the project is to develop new predictive models, and to include them in computing tools for the design of new nickel-base superalloys for aeronautical, energy and chemical engineering applications, through an automatic optimisation of composition by multi-objective genetic algorithms. Alloy design tools already exist and rely on a number of predictive models; we intend to extend the range of predictive tools by developing, in the case of multi-phase Ni alloys, on the one hand a model for dynamic recrystallisation (DRX) and on the other hand a model for the resistance to hydrogen embrittlement (RHE). First, computational thermodynamics will allow calculating the compositional dependence of microstructure, through the prediction of the nature and fractions of secondary phases, as well as of the driving force for nucleation, which will be used to evaluate the precipitate size and density. Then, the new models will describe the roles of precipitates on DRX (by acting as nucleation sites for the formation of new grains, or at the opposite by acting as pinning centres for grain boundaries, limiting their mobility and hence retarding or inhibiting DRX), and on RHE (by influencing, among others, the distribution of hydrogen between the matrix, the precipitates, the grain boundaries and the precipita
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Economic Nationalism and the European Union: The case of the automobile industry' (ECONAT) targeting Seventh Framework.

assistant: **Abstract**

Heated debates about ‘Buy American’ clauses and ‘British jobs for British workers’ have demonstrated the continued salience of economic nationalism as a public policy issue today. Among scholars, too, there has been a growing interest in the theme in recent years, which has gone hand in hand with a shifting understanding of economic nationalism away from a mere focus on state policies, and towards broader notions of collective identity. Building on this work the project sets out to analyse the relationship between economic nationalism and the process of European integration since the launch of the Single European Market in the mid1980s. Situated at the intersection between European studies and International Political Economy literatures the project will conceptualize this relationship in a twofold way, on the one hand, adopting the broader ‘Europeanisation’ framework, in terms of the EU impact on economic nationalism in selected member states, on the other hand with regard to possible trends of ‘supranationalisation’ of economic nationalism. The automobile industry will be chosen as a case study for the analysis. The project will result in the publication of a monograph, and will thus crucially help to advance the career of the applicant.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'International experiences of digital empowerment in a climate justice frame' to be submitted under Horizon 2020.

assistant: **Abstract**

This project aims to explore whether and (if so) how individuals affected by climate change experience and perceive empowerment through digital crowdsourcing campaigns provided by organisational actors. Unequal inclusion in climate change debates and decision-making processes remains a significanThis project aims to explore whether and (if so) how individuals affected by climate change experience and perceive empowerment through digital crowdsourcing campaigns provided by organisational actors. Unequal inclusion in climate change debates and decision-making processes remains a significant global problem, perpetuating local and global structural inequalities in experiencing and addressing climate change . In response to this issue, various international non-governmental civil society (INGO) and governmental organisations (IGO) have initiated crowdsourcing campaigns to involve citizens around the globe. Such campaigns provide open calls through digital platforms with varying aims around participation, ranging from individual submissions of climate change data (e.g. photo evidence or disaster tracking) to group submissions of innovative solutions to specific environmental problems. As such, these campaigns aim to provide more participatory processes. They should therefore, in theory, empower individuals through more participatory digitally-enabled processes (= digital empowerment), a notion and hypothesis this project aims to test through the lens of climate justice. It will do so through qualitative research including short-term ethnographic fieldwork with the WWF & UNFCCC; long-term digital observation (and where possible participation, e.g. in group tasks or data submission) in crowdsourcing initiatives by the UNFCCC (= 3 initiatives, drawn from COP27 crowdsourcing acti
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Molecular control of human adipose tissue hormone sensitive lipase - hsl - relation with in vivo" lipolytic activity"' (1994-1998) targeting Fourth Framework.

assistant: **Abstract**

The general aim of the project is to study the cellular and molecular regulation of human adipose tissue HSL in physiology and pathology (obesity, metabolic syndrome), in relationship with the in vivo" control of lipolysis. This will be achieved using "in vivo" and "in vitro" approaches. In the first part, lipolysis (in the basal state and its response to insulin catecholamines) and therefore HSL activity will be studied by microdialysis of abdominal and gluteal sub-cutaneous adipose tissue. For "in vitro" studies, isolated adipocytes will be obtained from biopsies of sub-cutaneous human adipose tissue from patients and control subjects. HSL response to insulin and A or B adrenergic agents will be measured and the expression of HSL will be determined. Moreover, we shall analyze sequences coding for HSL structure and study the regulation of its expression, looking for point mutations which could explain the effects in HSL function. "
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Sixth Framework proposal on 'To spread bioinformatic knowledge applied to functional genomic'.

assistant: **Concept**

Genomic research promises important advancement in disease classification and treatment as well as in developing new drug therapies. In the 6FP, the EU identified the genomic research as strategic field in Life Sciences and one of the priorities to improve human health. Bioinformatics is intrinsically linked to the development of advanced genomic. In the 6FP the bioinformatic is also indicated as a strategicarea of development for the EU. Unfortunately, bioinformatic skills are not sufficiently diffused in EU. The objective of this project is to train an experienced researcher of the Host Organization staff with strong molecular biology and genetic background to develop bioinformatic skills in functional genomic areas. The researcher will spent 12 months at the Partner Institution that has an international reputationand solid experience in bioinformatic and functional genomic fields. This researcher will be, then, reintegrated in the Host Organization. Simultaneously, following an international call of vacan cy, an experienced computer scientist will be hired by the Host Organization for 18 months. These two researchers will transfer knowledge to the Host Organization to extend its potential in functional genomic research. The major objective of this project i s to let the Host Organization to acquire strong bioinformatic skills so that a fully functioning Core Facility" for gene-array and functional genomic can be established. Through the activities of the "Core Facility" all the know-how developed in bioinfor matics and functional genomic will be transfer to other researchers of the team directly involved in this project aswell as to other research groups of the Host Institution. Moreover, being the Host Institution a University, the know-how will be also trans ferred