RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Agricultural Productivity and Technology Adoption in Sub-Saharan Africa' (ADAPT).

assistant: **Concept**

Agricultural productivity is strikingly low in much of Sub-Saharan Africa, exposing the large fraction of the population who lives from agriculture to low incomes and periods of hunger. Despite high returns to modern agricultural inputs elsewhere, their adoption in the region has been persistently low over the past decades. In the absence of adaptation, climate change is expected to severely impact the agricultural productivity of Sub-Saharan Africa. I propose three projects which will significantly improve our ability to understand the effect of modern agricultural inputs for agricultural productivity, and encourage their efficient adoption. First, existing methods for measuring the outcome of interest are notoriously imprecise, or costly, which is a fundamental limitation for research on agricultural productivity in developing countries. I will develop and evaluate an approach to substantially improve the precision with which researchers can measure agricultural output, at low costs. Second, existing approaches to encourage the adoption of modern agricultural inputs have had muted success. I will test a potentially highly impactful, novel approach: teaching farmers how to assess the returns to agricultural inputs on their own plots. In light of heterogeneous returns to input adoption across plots, this promises to encourage the right farmers to adopt the right inputs for their plots. And third, existing approaches to assess the degree of misallocation of inputs and associated output losses rely on strong functional form assumptions. I will leverage the plot-level estimates of returns generated in the second project as well as the knowledge embedded in bio-physical models of plant growth to quantify the extent of misallocation of inputs in agriculture. This radically n
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Social Innovations Promoting Active and Healthy Ageing'.

assistant: **Objectives**

INNOVAGE is an ambitious project is dedicated to developing and testing, as well as surveying and cataloguing, social innovations that will have a solid impact on improving the quality of life and well-being of older people.  In particular the project aims to make a major contribution to the EU goal of extending healthy life years.  It has four clear and achievable objectives that are intended to create a new paradigm in this field.  These objectives directly address the present major barriers to innovation and to the achievement of the extension of healthy life years across the EU.  The expert multi-disciplinary team is based on a highly successful existing collaboration, which will enable fast take-off and the guarantee of excellent team work.  The work packages are designed to achieve impact in the public, private and third sectors.  The project is built on the closest possible partnership with end users (or stakeholders) including older people themselves.  It will deliver not only four new major social innovations in different EU countries (services models and products) but also a new European platform to promote knowledge exchange about and the sustainable implementation of social innovations to promote well-being in later life.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'New Technology for Multi-Axial, Slim and High Performance Timber Structures' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Buildings are responsible for 36% of total EU emissions of carbon dioxide (CO2). Concrete has been an excellent choice in the buildings construction, nevertheless is responsible for emitting 500 kg of CO2 per 1m3 of concrete used. Triggered by these facts EU has already set binding targets for CO2 reduction for which alternative safe techniques to build buildings in a carbon neutral manner will be crucial. Timber is a structural solution that has a much lighter carbon footprint than functionally equivalent concrete systems since it absorbs and stores 1 ton of CO2 per 1 m3 of timber. Nevertheless, all known timber building systems allow only slabs with a uniaxial load bearing action. Thereby, in comparison to normal reinforced concrete slabs, timber slabs are often thick, expensive and complicated to build, since there is no efficient connection technology to rigidly connect timber slab elements to each other. TS3.0 technology represents the next generation of timber constructions aiming to realise typical skeleton buildings using only timber. We offer the possibility to build beams and slabs in any length and size and our proprietary butt-joint bonding technology allows the bonding of timber parallel to the grain. Therefore, timber beams by almost any length or plates of almost any dimension can be produced (i.e. rigid walls, floors or shells of any shape). Through the project we expect to reach €26.7 million revenues five years after its commercialization.  Phase 2 will require an investment of close to €2 million, which will present a Cumulative Return of Investment of 5.9.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Structural and functional characterization of proteins partners of vavprotooncogene' under Fourth Framework.

assistant: **Concept**

Research objectives and content The objective of my proposal is to characterize new partners of the proto-oncogene Vav, in order to learn more of its role in signalling pathways. vav is expressed mainly in cells of hematopoietic origin and displays a complex array of structural motifs that implicated Vav as an adaptor linking cell surface receptor to downstream signalling cascade. Although the analysis of mice deficient in vav expression (vav-/- ) has shown the essential role of this proto-oncogene in T and B cell proliferation, the downstream signalling molecules associated to Vav are mostly unknown. To identify new transducing molecules interacting with Vav I used the SH3-SH2-SH3 domains of Vav to screen a lymphoid cell cDNA library by the yeast two-hybrid system and I isolated humSiah2, a new human homolog of the Drosophila Seven in Absentia gene (Sina). Sina encodes a ringfinger-containing nuclear protein reqtured for the correct integration of signal transduction downstream of the tyrosine kinase receptor sevenless during R7 photoreceptor development. At the moment the role of Sina/humSiah2 proteins is unknown. Further characterization of the signalling pathways in which they participate are also required. I will start by characterizing Vav/humsiah2 interaction in an in vivo context by coimmunoprecipitation and coimmunolocalization experiments. In the same time I will develop studies aimed at understanding the functional role of humSiah2 in order to clarify the biological significance of humSiah2/Vav interaction and to precise the pathways in which both proteins are involved. For this purpose I propose to investigate: a) the modulation of humSiah2 expression and localization in resting and activated hematopoietic cells; b) the effect of the overexpression of exogen
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Versatile targets for the interaction with a laser' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

The VERTICAL (Versatile targets for the interaction with a laser) proof of concept project will exploit the innovation potential of laser-driven gamma ray radiography. This initiative ambitions to deliver transportable and reliable high repetition rate gamma-sources to answer to identified industrial probing needs of rapidity, compactness and safety.The ERC Proof-of-Concept 2011 call represents an opportunity to address, from 2012, the economic and technical parts of the VERTICAL project.The economic part consists in the achievement of a sound international market study to unveil the full commercial potentialities of our proof-of-concept, the creation of a venture (called SourceLAB) dedicated to the development and to the commercialization of innovative compact X- and gamma-sources, and the registration of patents and handling of Intellectual Properties Rights (IPR). The technical part consists in the development of innovative target prototypes for X-and gamma-tomography at high repetition rate, the development of precision targetry for shaping an intense laser pulse at high repetition rate, and the development of a high added value kit « laser + target », in partnership with the laser technology industry, for broader applications (secondary sources of particles and radiations) in the field of laser-plasma interaction.The possible success of the innovative VERTICAL project is regarded as a significant breakthrough for societal applications in dense matter probing (cargo scanning, facility safety, component defect detection) of the research about LPA, underlied by the ERC PARIS project, with also very positive impact for the academic and industrial activities in laser-plasma interaction and eventually, a promising dispersion in the society of safe laser-driven sources of
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'DYNamic Management of Aircraft Configuration and Route Structures' (DYN-MARS) targeting Horizon Europe.

assistant: **Abstract**

The DYN-MARS project aims to minimise the environmental footprint of flights during climb, descent and approach through novel avionic functions and improved arrival routes and procedures. It enables, for the first time, a complete holistic solution that combines airborne with Air Traffic Management (ATM) improvements connected by enhanced communication capabilities.DYN-MARS builds on previous SESAR work through the development of the permanent resume trajectory function, the concept of dynamic deployment of arrival route structures, the DYNCAT projects Flight Management System (FMS) energy management function and new airground data exchanges in order to enable the visibility of the flight plan at both ends.The DYN-MARS solution will consist of both an enhanced FMS for aircraft and new airspace management techniques for Air Traffic Control (ATC). This solution opens the path for more environmentally friendly routing of aircraft in the terminal manoeuvring area whilst maintaining todays safety level.Based on the uplink of dynamically assigned routes and other information, DYN-MARS aims to allow pilots to better plan their optimum vertical and speed profile in descent and approach while maintaining the required runway throughput. Downlink of the FMS computed trajectory allows for further improvement in the trajectory optimisation process between the aircraft and ATC. Increased flexibility in ATM will make it possible accommodate these optimised flight profiles. DYN-MARS will conduct 5 different exercises to validate its solution from both avionics and ATM points of view with related human performance aspects.DYN-MARS includes relevant aspects of air traffic management with new aircraft flight procedures to sustainably reduce the environmental impact of aviation (CO2, fuel
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Minority Languages, Major Opportunities. Collaborative Research, Community Engagement and Innovative Educational Tools' (COLING) under Horizon 2020.

assistant: **Objectives**

The linguistic and cultural diversity of Europe is crucial to the capacity for problem solving and creative thinking upon which our general wellbeing and economic prosperity depend in an increasingly global and technological society. However, language diversity and immigration are often seen as threats and are challenged by discriminatory attitudes and state policies. COLING will provide justification for the strengthening and revitalization of minority languages, as well as guidelines to implement concrete programs for this purpose. The project’s objectives focus on developing and sharing expert knowledge on language revitalization programs that combine community-driven and top-down approaches; promoting engaged collaboration among academic, nonprofit and community-based institutions; developing efficient teaching methodologies, teacher training, and curricula for minority languages; establishing a new international academic program in minority studies at the partner institutions, in which the new methodologies and curricula will be employed. To this end, COLING affiliated researchers will work together to a) document and archive linguistic-cultural diversity and language practices of indigenous communities and migrants; b) explore the Trans-Atlantic perspectives and historical ties between the Americas and Europe that demonstrate the cultural resilience of indigenous peoples and the evolution of heritage cultures in mixed societies; c) develop innovative teaching methodologies through content modules in textual and digital formats and d) investigate the causative and correlative relationships between language identities, linguistic and cultural discrimination, self-confidence, trauma and well-being, and social cohesion in multilingual and multicultural contexts. COLIN
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Molecularly Imprinted Nanofibres for Tissue Engineering, Affinity Depletion and Biosensor Applications' (MIFS4BIOMED), addressing dissemination and exploitation.

assistant: **Impact**

Molecular imprinted polymers and electrospun nanofibres are both hot topics individually in the biomedical sciences, with applications including tissue engineering, regenerative medicine, drug release, affinity chromatography and biosensors. This proposal combines these two leading-edge approaches to generate entirely novel materials with broad utility in biomedical engineering. Molecular imprinting is a form of template assisted synthesis that facilitates the creation of artificial receptors that can have affinity constants as high as their natural counterparts. Electrospinning (ES) is one of the most broadly used techniques for fabrication of nanostructured materials. ES uses electrical forces to produce continuous fibres having diameters in range of few nanometers to several micrometers. ES offers several technical advantages such as extremely high surface area per unit volume, tunable porosity, flexibility for adapting it to different shapes and sizes, and possibilities for controlling nanofibre composition.In this proposal, we have focused on next generation molecular imprinting using reactive electrospinning to obtain directly imprinted nanofibres. We will demonstrate the utility of this new nanofabrication technology in three key areas: active agent carriers in regenerative medicine, affinity depleting membranes in blood-related proteomics, and biorecognition elements for biosensors. The multidisciplinary nature of the project will make important contributions to the development and validation of new therapies, sustainable and efficient healthcare systems, and strengthening the competitiveness and innovative capacity of European health-related industries. We will be working at the frontiers of two leading research areas having the potential to attract the attenti
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Role of the kinase TAOK2 in the innate immune response to viral infection', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Viral infections are a major threat to public health worldwide. The innate immune response acts as the first line of defense during viral infections by recognizing pathogen-associated molecular patterns such as double-stranded RNA (dsRNA). Impaired innate immune signaling sensitizes patients to viral infections, while aberrant innate immune activation is associated with autoimmune diseases. Recently, the host laboratory identified the protein kinase TAOK2 as a novel co-factor for viral dsRNA sensing. TAOK2 binds and is activated by dsRNA, and its depletion leads to an impaired immune response to viral infection. Notably, a mutation in TAOK2 causes immunodeficiency in human patients. These findings suggest a previously unappreciated role for TAOK2 in innate immunity, but the molecular details remain unclear.I will use synergistic biochemical, systems biology and in vivo approaches to comprehensively define the role of TAOK2 in innate immunity. First, I will use state-of-the-art biochemical and structural approaches to define the mechanism of dsRNA recognition by TAOK2 and discern the molecular basis for the disease-causing point mutation. Second, I will perform a multi-level systems biology analysis to integrate TAOK2 into a dynamic signaling network in response to viral infection. Third, I will assess the consequences of complete loss of TAOK2 and the clinically relevant TAOK2 point mutation in vivo using mouse models. This highly interdisciplinary and collaborative project will combine my existing expertise in biochemistry and in vivo approaches with the systems biology competencies of the host laboratory. Thereby, I will gain novel insight into the signaling network that governs the innate immune responses to viral dsRNA. The training during this project will increase
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'A European Platform for the Communication of European RTD results to Stakeholders in Fisheries and Aquaculture' demonstrating excellence, impact and implementation quality for a Sixth Framework call.

assistant: **Abstract**

PROFET Policy proposes to build a platform for the communication and dissemination of the results of EU-funded research projects, in fisheries and aquaculture, of the 5th and 6th Framework Research Programmes.Use of modern communication tools will be used to facilitate the flow of information of policy-relevant results to a wide-range of stakeholders, using primarily a web-based structure for the publishing of Technical Leaflets.Seminars will be organised on a thematic and regional basis, covering fisheries and aquaculture, which will focus on promoting an exchange of views between aquaculture producers, fishers, scientists, National and European policy-makers and other stakeholders.Core elements of the seminars will be the presentation of results and discussion of the RTD needs of each sector so as to recommend clear guidelines and topics for future European Union Research Programmes. Member Organisations of the representative European Associations will be closely involved in the organisation of the seminars.The PROFET POLICY workshops will also provide a platform for the presentation of ongoing FP6 projects under the area of scientific support to policy, as well as established fisheries and aquaculture organisations and networks that have direct relevance to the individual workshop theme, using posters or presentation stands, thus providing valuable exposure of these projects to policy-oriented stakeholders.PROFET Policy builds on the experience and results of Aquaflow and PROFET, involving partners from these successful projects, with further development of the ICT and management tools developed in addition to the use of well established networks for communication and dissemination. This aspect assures cost-effective and experienced management for the project.