RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'A-l-fucosidase and its use to modify the xyloglucan-cellulose network of plant cell walls'.

assistant: **Concept**

Research objectives and content The texture (and hence quality) of vegetables and fruits is influenced strongly by the mechanical properties of the plant cell wall. Although there is considerable knowledge of the structures of cell wall polymers and of the mechanical properties of cell walls and tissues, a major and persistent problem is a lack of knowledge of how altered molecular structures within cell walls translate into changes in mechanical properties. My doctoral work in Spain has focused on the role of the cell wall associated peroxidases in the stiffening of the cell wall during growth. It would greatly enhance my future research potential if I were to gain experience in the major polysaccharide networks of cell walls, and at the same time acquire experience in molecular biology. I would therefore like to join of Professor J S Grant Reid's laboratory to participate in an investigation of the effect of xyloglucan structure modification on the properties of xyloglucan-cellulose networks. The objectives of the work I propose in Professor Reid's laboratory are (1) to purify a xyloglucan-active a-L-fucosidase from germinated nasturtium seeds in quantities sufficient to allow its use to modify xyloglucan structure in vitro on a hundreds-of milligrams scale (2) to prepare fucose-modified xyloglucans to be assessed, in collaboration with Industry, in novel cell wall like in vitro-assembled cellulose-xyloglucan networks and (3) to obtain a cDNA clone of the fucosidase with a view to future overexpression of the enzyme. Training content (objective, benefit and expected impact) Professor Reid's laboratory at U Stirling enjoys world status in the isolation and molecular characterization of natural plan enzymes capable of modifying the important cellulose-xyloglucan network
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Multi-disciplinary biodosimetric tools to manage high scale radiological casualties'.

assistant: **Innovation**

In the event of a large scale radiological emergency biological dosimetry is an essential tool that can provide timely assessment of radiation exposure to the general population and enable the identification of those exposed people, who should receive medical treatment. A number of biodosimetric tools are potentially available, but they must be adapted and tested for a large-scale emergency scenario. These methods differ in their specificity and sensitivity to radiation, the stability of signal and speed of performance. A large scale radiological emergency can take different forms. Based on the emergency scenario different biodosimetric tools should be applied so that the dosimetric information can be made available with optimal speed and precision. The aim of this multi-disciplinary collaborative project is to analyse a variety of biodosimetric tools and adapt them to different mass casualty scenarios. The following biodosimetric tools will be validated and established: the dicentric assay, the micronucleus assay, the gamma-H2AX assay, the skin speckle assay, the blood serum protein expression assay and EPR/OSL dosimetry in components of pocket electronic devises. The assays were chosen because they complement each other with respect to sensitivity, specificity to radiation and the exposure scenario as well as speed of performance. The project will involve the key European players with extensive experience in biological dosimetry. Training will be carried out and automation and commercialisation pursued. An operational guide will be developed and disseminated among emergency preparedness and radiation protection organisations. The final deliverable of this project will be establishment of a biodosimetric network that is fully functional and ready to respond in case of
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Vision optics with Integrated VCSELs and Autofocal Lenses'.

assistant: **Innovation**

Intelligent devices like smartphones, PCs, smart watches, cars and machines require active visual attention and manual interaction of the user for operation and control, such as by touch screens. This is not convenient for many applications and also causes user distraction, which may be not acceptable for safety critical situations that require full visual attention, e.g. driving, health applications or control of machines. Eye-tracking (ET) systems integrated into smart glasses can use parameters like gaze direction or motion of the eye and the eyelid to control the device. ET can therefore pave the way for completely new hands-free human machine interfaces (HMIs) suitable not only for critical applications but also in general for a more comfortable user interaction, e.g. for consumer devices, industrials applications or education. However, conventional camera-based ET systems suffer from high costs, complexity, high weights and dimensions as well as sensitiveness regarding ambient conditions. Therefore, ET is currently applied for some specific use cases but has yet not reached broad market acceptance.The VIVA project will develop the technologies to enable a new class of eye-tracking systems, which will be light-weight, small, power efficient, fast, reliable and highly accurate under nearly all ambient conditions. The project will integrate and further develop novel sensors based on Laser Feedback Interferometry, small and light meta-optics as well as AI methods and hardware for signal processing and feature detection. The overall eye-tracking system will be verified and demonstrated by typical use cases. Along with these developments, the new ET technology will be analyzed regarding privacy, data security, safety and CE conformity. All in all, the outcome of VIVA wi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Versatile and Innovative Detector for Electron Optics' to be submitted under Horizon 2020.

assistant: **Abstract**

The VIDEO project will professionalize and integrate software and develop open standard file formats for electron microscopy based on results from the ERC Advanced Grant project IMAGINE, supplemented with results and support from other research groups and hardware vendors. Our goal is to combine these separate activities into an open software platform and to develop open standards, which will enable vendors and users to develop interoperable solutions in this area, and to explore business and sustainability models.Over the last 20 years, electron microscopy has developed from a technique that provides magnified images to become a complex ultra-high resolution analytical tool. Data sets are no longer single qualitative images, but collections of quantitative multi-channel signals. This new approach to using an electron microscope makes developing software to control the experiments and to process the resulting data an integral part of creating and improving electron microscopy techniques. Recently, pixelated detectors have been developed for scanning transmission electron microscopy. For the first time, they allow efficient capture of complete frames of scattered intensity for each scanned pixel. We have been using such novel pixelated detectors to measure nanoscale electromagnetic fields as part of the underlying ERC Advanced Grant IMAGINE. However, software support for these detectors is still in its infancy, with image capture and very basic analysis capabilities provided by the detector vendors and experimental one-off data analysis scripts developed by users.The goal of the VIDEO project is to combine these efforts by creating full software support for pixelated STEM and finding a business model to sustain this open platform as a powerful starting point for an open,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Sound to sense' (S2S), addressing dissemination and exploitation.

assistant: **Impact**

The aim of this RTN is to elucidate the interaction of knowledge and sensation in speech perception, by developing a psychological/computational model of speech recognition that reflects the flexible response to the availability of information in the sign al that is comparable to that of humans listening to their native language (L1). A central focus is to track how phonetic information, especially fine phonetic detail that varies systematically with linguistic/interactional structure and function, is used under different circumstances: when the listener has appropriate linguistic-phonetic knowledge (listening to L1), possibly inappropriate or inadequate knowledge (listening to a foreign language (L2)), and inadequate access to the signal (listening in adverse conditions). A related focus is to elucidate how phonetic information contributes to understanding: modelling will reflect known attributes of auditory processing, and linguistic and statistical properties of language units. The ultimate aim is to provide models of speech perception that closely reflect the flexibility and robustness of human speech recognition, that pave the way for the next generation of robust automatic speech recognition and text-to-speech machines, and promise to offer a new theoretical basis for L2 teaching and for diagnosis and treatment of speech disorders. Cross-disciplinary training is essential to achieve these aims: no single discipline or pair of disciplines currently teaches all the information and skills required to achieve them, many work independently of the others, and some assume old models that have been superseded in other disciplines. By nurturing a sufficiently large group of scientists who will lead a sustained, cross-disciplinary effort to understand human speech processin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Timing of Holocene volcanic eruptions and their radiative aerosol forcing' in the context of a Horizon 2020 call.

assistant: **Objectives**

Volcanic eruptions play a dominant role in driving climate, in ways beyond the established short-term influence on surface air temperatures. In order to mitigate and adapt to the climate effects of future large volcanic eruptions we need to better quantify the risk of these eruptions including 1) the probability of their occurrence and 2) their expected climatic impact. The observational record of the timing of volcanic eruptions, their locations, magnitudes of sulphate aerosol injection is incomplete which limits our understanding of the sensitivity of the Earth system to volcanism and the vulnerability of social and economic systems to the climate impact of past and future eruptions. The primary goal of this proposal is to extract data on the timing, magnitudes and source locations of all major volcanic eruptions occurring during the Holocene (i.e., the past 12,000 years) to answer the questions: What is the likelihood of a stratospheric sulfur injection as large as that from the colossal eruption of Tambora in 1815 to occur somewhere on the globe within the next 100 years? What is the role of effusive eruptions on past, present and future climate? This will be achieved by employing novel, precisely dated, high-time resolution aerosol measurements from bipolar ice-core arrays. New tools will be used to constrain source parameters of the eruptions (location, plume injection height) that control their effects on climate. THERA will constrain recurrence rates for one of the largest global-scale natural hazards, while also assessing linkages between volcanic perturbations and key components of the climate systems (e.g., atmospheric circulation, droughts, ice-sheets and sea-level) through interdisciplinary case studies. As a final goal, THERA will generate global-scale, sp
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Privacy for Smart Speech Technology' (PSST), addressing dissemination and exploitation.

assistant: **Impact**

The unabated rise of smart speech technology, much of which is operated by entities outside of the European Union, has revolutionised consumer access to information and applications using the most convenient interface of all - the human voice. Recently, however, we have come to understand that smart speakers, smartwatches and other voice-operated devices may expose their users to privacy risks. Service operators and hackers alike can access not only spoken words but may also exploit sensitive non-lexical information contained within speech signals (such as health status) for nefarious purposes without the users’ knowledge or consent.However, innovative privacy-preserving smart speech technologies may mitigate these risks and help to create sustainable business models that are well aligned with EU regulations such as the GDPR and the forthcoming EU Artificial Intelligence (AI) Act. Therefore, the PSST joint doctoral training network will train a new cohort of researchers to develop these urgently-needed technologies using cutting-edge deep learning methods. PSST will focus on the suppression of speaker traits in speech signals, on enhancing usability in interactions between smart devices and cloud services, and on novel evaluation schemes that consider the most relevant threats. The PSST consortium is composed of world-leading research labs in speech processing, privacy and usability, and a larger number of innovative industrial partners. The joint academic-industrial partnership will establish a high-impact training programme that provides doctoral researchers with expertise in speech processing, machine learning and comprehensive knowledge of privacy threats and privacy-enhancing technologies.PSST partners and researchers will jointly create not only a unique, user-cen
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'G-quadruplexes in the HIV-1 genome: novel targets for the development of selective antiviral drugs' (2007-2013), addressing dissemination and exploitation.

assistant: **Impact**

G-quadruplexes (G-4) are polymorphic nucleic acid structures identified in gene promoters where they act as transcription regulators. G-4s have been found in eukaryotic and prokaryotic organisms, while very little information is available on viruses. The applicant research group has recently shown that HIV-1, which integrates into the human chromosomes and exploits cellular factors to activate transcription, takes advantage of G-4-mediated transcription regulation. G-4 disruption stimulates promoter activity while G-4 stabilization by small molecules inhibits it, showing a striking parallelism between HIV-1 LTR and eukaryotic promoter G-4s. Preliminary results indicate that similar G-4 structures form also in the viral RNA genome before retrotranscription. Available G-4 ligands, developed as anticancer drugs targeting DNA G-4, recognize both viral and cellular G-4s. Therefore, they cannot be straightforwardly used as anti-HIV compounds. The aim of this project is to develop highly specific anti-HIV-1 drugs targeting LTR DNA and/or RNA G-4s, using both reversible G-4 ligands and G-4-selective alkylating/cleaving agents, triggered by external stimuli. These approaches will be taken: a) to increase selectivity by 1) screening of ligands against LTR G-4s to select the best hits among libraries of G-4 ligands; 2) conjugation of the most promising leads to modified nucleic acids complementing LTR G-4 loop/flanking regions, to deliver the drug to its target; b) to stabilize binding by conjugation of the ligands to 3) an alkylating/cleaving subunit, and 4) an activable moiety (such as quinone methides) that alkylates the target only once the drug has reached it. Physico-chemical, biomolecular, cellular and viral assays will be used to tests the compounds. This approach should d
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'FIRE-IN - Fire and Rescue Innovation Network' in the context of a Horizon 2020 call.

assistant: **Objectives**

FIRE-IN has been designed to raise the security level of EU citizens by improving the national and European Fire & Rescue (F&R) capability development process. FIRE-IN addresses the concern that capability-driven research and innovation in this area needs much stronger guidance from practitioners and better exploitation of the technology potentially available for the discipline. We argue that this is to be achieved by practitioners more effectively coordinating on operational needs, on available research and innovation, on standardisation, and on test & demonstration and training.  Further, we claim the need for the development of a common research culture that is to be achieved by better cooperation between practitioner and research/industry organisations. FIRE-IN addresses these objectives through four main areas of activity: (i) the identification and harmonisation of operational capability gaps based on the contribution provided by a significant and heterogeneous practitioner network, (ii) the identification of promising solutions to address those gaps through monitoring and screening of research outcomes and the continuous involvement of research and industry representatives, (iii) the definition of a F&R Strategic Research and Standardisation Agenda (SRSA) based on the previous  elements as well as (iv) the development of a concept for more efficient use of test & demonstration and training facilities to support innovation and joint skill development. The overarching result of the project will be a proven process for organising F&R capability-driven research based on a wide practitioner and research and innovation network. The network will be linked at cross-domain and cross-border level and will feed harmonised operational requirements (or challenges) into nation
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'Development of field measurement of ventilation, based on tracer gas techniques, using innovative air sampling and tracer gas emission technology'.

assistant: **Objectives**

The indoor climate and the indoor air quality comprises issues of large interest for public health and economy. People spend nearly 90% of their time indoors (dwellings, offices, schools, factories etc.). The levels of air contaminants indoors are also significantly higher indoors than outdoors in all types of environment. An indoor/outdoor factor of 10 is common for most organic compounds. The reason for this is that emissions from indoor contaminant sources accumulates indoors due to limited available ventilation rates. Due to thermal comfort reasons and energy consumption aspects, the ventilation rate of buildings must be limited to reasonable levels, while the public health requires adequate freedom of contaminants. National guidelines and regulations about minimum acceptable ventilation rates in different indoor environments have therefore been established in most countries. An increasing prevalence of allergies, hypersensitivity and diffuse health symptoms (sick-building-syndrome), now approaching an epidemic Ievel, has focused the interest to contaminant sources and adequate ventilation of the indoor environment. The goal of the CRAFT-project is to develop new simple and reliable passive" tracer gas techniques for field measurement of ventilation, to introduce it into new areas of application and to broaden a European and a non-European market for measurement equipment and services. The RTD work will serve three goals: Support technical development of two innovative techniques for measurement of ventilation and air distribution in buildings. The first one is a technique which allows measurement during pre-determined time intervals during an extended period. The second one is a quick, reliable and inexpensive technique for measurement during short periods of time.