RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Revolutionary opto-biological methodology for aggressive HER2 cancer'.

assistant: **Concept**

According to World Health Organization, cancer is one of the leading causes of morbidity and mortality worldwide, with approximately 14 million new cases per year. Breast cancer is the most common cancer among women, and is considered the second most common cancer overall. Each year about 1.7 million new cases are diagnosed worldwide and over 500,000 women die from the disease.  Current diagnosis methods of cancers fail to deliver objective results. Diagnosis require extracting tissue samples via invasive and expensive biopsy, followed by laboratory analysis, which are subject to significant levels of discordance. SDS Optic presents a revolutionary opto-biological methodology that allows for instant cellular processes studies including in-vivo cancer diagnosis with single-cell resolution. SDS-OmiProbe detects presence and measures concentration levels of the HER2+ cancer cells in breast tumours. It is a breakthrough device that carries the potential to address the challenges of SoA cancer markers diagnosis and biopsies. In essence, it is a laboratory test at the tip of a probe, but with greater accuracy, efficacy and quantitative results. SDS-OmiProbe may also be used as a companion diagnostic tool for targeted therapy and targeted therapy drugs. There is compelling evidence that our novel SDS-OmiProbe is addressing a rapid growth trend in a high volume market. Based on Transparency Market Research Report the OmiProbe target market of HER2- biomarker tests is projected to be worth $4.6 billion, with 7.5 million HER2 marker tests performed annually worldwide.In order to close the striking gap in the landscape of currently available cancer diagnostic and targeted therapy tools, and to realize the significant global business opportunity the objective of this project is opt
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Relaxation dynamics in closed quantum systems'.

assistant: **Innovation**

Statistical mechanics, a century-old theory, is probably one of the most powerful constructions of physics. It predicts that the equilibrium properties of any system composed of a large number of particles depend only on a handful of macroscopic parameters, no matter how the particles interact with each other. But the question of how many-body systems relax towards such equilibrium states remains largely unsolved. This problem is especially acute for quantum systems, which evolve in a much larger mathematical space than the classical space-time and obey non-local equations of motion. Despite the formidable complexity of quantum dynamics, recent theoretical advances have put forward a very simple picture: the dynamics of closed quantum many-body systems would be essentially local, meaning that it would take a finite time for correlations between two distant regions of space to reach their equilibrium value. This locality would be an emergent collective property, similar to spontaneous symmetry breaking, and have its origin in the propagation of quasiparticle excitations. The fact is, however, that only few observations directly confirm this scenario. In particular, the role played by the dimensionality and the interaction range is largely unknown. The concept of this project is to take advantage of the great versatility offered by ultracold atom systems to investigate experimentally the relaxation dynamics in regimes well beyond the boundaries of our current knowledge. We will focus our attention on two-dimensional systems with both short- and long-range interactions, when all previous experiments were bound to one-dimensional systems. The realisation of the project will hinge on the construction on a new-generation quantum gas microscope experiment for strontium gases.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Identification of molecular mechanisms involved in temperature perception and signalling in Brachypodium' (BRACHYTEM).

assistant: **Concept**

Being sessile and unable to regulate their internal temperature, plants are exposed to large variations in ambient temperature during day-night cycles and seasonal changes. It is clear that plant development and growth are closely related to thermal conditions, but the molecular mechanisms involved in temperature sensing are not understood. Plant responses to changing ambient temperature are becoming increasingly important from an applied perspective, due to the projected 2.0-5.4°C global warming by the end of this century. To understand plant responses to temperature, we need to resolve the molecular components involved in temperature perception and signalling. I will use a multidisciplinary approach combining molecular genetics and growth and developmental analysis to understand temperature perception and responses in the emerging model monocot system Brachypodium distachyon. The results will be highly relevant for other temperate grasses and cereals, due to their close phylogenetic relationship. First, the temperature effect on Brachypodium leaf meristem functioning will be quantified using kinematic methods, making use of new reporter lines for meristematic activity. Second, the genetic network involved in correct ambient temperature sensing and signalling will be identified by extensive forward genetic screening based on LUC reporters and fast neutron deletion mutant populations. The gene mapping will be strongly enhanced using whole genome tiling arrays. The GA/DELLA pathway has been shown to restrain growth in adverse conditions in Arabidopsis. The third objective of this proposal is to identify components of the GA/DELLA pathway in Brachypodium in a reverse genetic approach by screening the genomic DNA bank of fast neutron deletion lines for the predicted DELLA
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'A cost effective and efficient approach for a new generation of solar dish-Stirling plants based on storage and hybridization'.

assistant: **Innovation**

In the context of the Energy SET-Plan of the European Commission relevant research and developments channelled to increase the percentage of renewable energy sources. It is crucial the collaboration of the Industry, SME’s and research institutions to bring together the step forward to finally integrate renewable energies as the main source of electricity.Renewable energies represent a wide field upon which international research needs to be focused. The necessity has been envisaged by the BIOSTIRLING consortium and it has been supported by the synergies found with the large-scale international project SKA. The SKA antennas and reception centres, constitute a continental scale sensor network. Aligned with the trend of renewable resources, the overall objective of the project is to implement a cost effective and efficient new generation of solar dish-Stirling plant based on hybridization and efficient storage at the industrial scale.In order to achieve successfully the ambitious objective, the collaboration performed by the consortium will take the advantage of the expertise of the members in the developing of a Solar Dish/Stirling system, which besides being more operative in terms of construction, transportation and commissioning, it will be more efficient than actual systems because an innovative storage device and a bio-hybrid energy collector will be developed to guarantee the electricity supply independently on time and weather conditions. Increased modularity of the system will enable the Solar Dish/Stirling system to act as an energy supplier not only to the grid but also in specific uses as supplying energy to the SKA project, which sets the most challenging power requirements of any Large Research Facility.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'The Dynamic Representational Nature of Working Memory' (DeepStore) targeting Horizon 2020.

assistant: **Abstract**

Working memory excels in keeping ready the momentary contents of all of human higher cognition despite being strictly limited in storage capacity. How the brain accomplishes this feat, beyond the temporary maintenance of just experienced information, is hardly understood. An emerging view suggests that working memory storage is topographically distributed according to the informations endogenous level of abstraction. However, very little is known about how such distributed storage is orchestrated spatiotemporally, that is, how representations at different levels of abstraction are structured dynamically in time to suit current demands. In DeepStore, we use tailored experimental designs and newly developed multivariate analysis techniques to explore for the first time directly the depth-dimension of working memory, in terms of dynamic levels of abstraction. Combining functional imaging, magneto-/electroencephalography, and invasive neural recordings will make it possible to track levels of abstraction spatiotemporally, with millisecond precision.In three ambitious experimental series, DeepStore will shed new light on long-standing open questions about working memory storage, including how it is modulated by attention, inattention, and distraction, and how multiple contents are stored simultaneously. The work will shape a new theory of the neurocognitive capacity limit in working memory. We will further test novel hypotheses about how working memory interfaces with long-term memory, and how it develops over the lifespan. Finally, we will combine our innovative human neuroimaging approach with direct electrophysiological recordings in non-human primates during the same task, to disclose the fine-grained neural mechanisms of dynamic abstraction down to the single-cell level
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Human on Chip : Microsensor unit and control algorithm integration for brain on a chip drug testing applications and development' (BrainChip), addressing dissemination and exploitation.

assistant: **Impact**

Cherry Biotech is an innovative French company which develops and commercializes microfluidic instruments for life sciences and healthcare. We position ourselves on a  biological research market in which we are developing a range of tools dedicated to high resolution imaging. Other cellular environment control systems are also in test or development to support business growth. This technical base and the transversal skills held by the team has ideally positioned Cherry Biotech to carry out ambitious projects in the growing market  of the Organs on a chip.The design, development and implementation of microfluidic devices called ""Organ-on-a-Chip"" require the understanding and the integration of numerous components (technical, biological issues and constraints ...).The candidate will take over from its genesis to the development of proof of concept the development of a microfluidic instrumentation platform to test therapeutic molecules on artificial organs (Brain) integrated within microfluidic chips. His challenge will be to integrate a complex technical environment (instrumentation, sensors, microfluidics) with important biological constraints.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Novel Blueprints for the Visible-Light-Mediated Assembly of C–N Bonds via Nitrogen Radicals' in the context of a Horizon 2020 call.

assistant: **Objectives**

Nitrogen-containing compounds underpin every aspect of our daily life as they form the structural basis of almost all pharmaceuticals, agrochemicals, food additives and materials. The invention of methods for the formation of bonds between C and N atoms is of strategic importance for the discovery and evolution of molecules with direct implications on the quality of our lives. Despite this fundamental relevance, forming C–N bonds is still a very challenging task.This proposal aims to deliver transformative advances for the development of new efficient and selective strategies for the synthesis of N-containing molecules by harnessing visible-light as inexpensive and sustainable source of energy. I aim to challenge preconceptions about the field of organic chemistry and to develop innovative methods to control, modulate and transform the reactivity of nitrogen-centered radicals (NCRs), an entire class of reactive intermediates for which there are only limited applications in modern organic chemistry. My research group has developed two novel visible-light-mediated ways of generating NCRs, and I aim to: (1) Harness and explore the unique features of visible-light-mediated transformations to provide novel multicomponent reactions of NCRs. (2) Establish NCRs as viable partners in asymmetric photoredox catalysis and use them for the easy construction of complex molecules with defined 3D shapes. (3) Merge the visible-light generation of NCRs with organocatalysis to enable novel dual catalytic asymmetric protocols. (4) Combine the NCRs with transition metal catalysis and discover unprecedented transformations that go beyond photoredox catalysis and transition metal catalysis alone.     This cohesive and innovative approach will develop new tools essential for the assembly of co
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Phd training in the research of international monetary economics' to be submitted under Fifth Framework.

assistant: **Abstract**

The Center for Economic Studies (CES) of the K.U.Leuven (Belgium) has recently been awarded the status of Marie Curie Training Site, in the field of international monetary economics. Therefore, the CES has a number of vacancies for fellows who are pursuing a PhD in economics, with a specialization in international economics for a period of minimum 3 months and maximum 1 year. The training that the CES offers is focused on the study of monetary integration and exchange rate economics. In addition, the CES organizes specialized seminars and courses in the area of international economics on a regular basis. The fellow will receive a monthly allowance according to the standard community contribution. The CES is an equal opportunity employer. Applications from women are warmly welcomed. Interested applicants should send their CV and 2 reference letters to : Prof. P. De Grauwe, K.U.Leuven, Center for Economic Studies, Naamsestraat 69, 3000 Leuven, Belgium.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'On the maximum energy of particles accelerated in astrophysical jets' (EMAXSHOCK), addressing dissemination and exploitation.

assistant: **Impact**

Astrophysical jets moving in an external medium produce shocks where particles can be accelerated via Diffusive Shock Acceleration (DSA). The main uncertainty is the maximum energy that particles can achieve, and this has important implications for different fields in astrophysics. In particular, one of the most exciting problems is  the origin of the Ultra High Energy Cosmic Rays, and jets from Active Galactic Nuclei (AGN) have been proposed as candidates. At lower energies cosmic rays are likely galactic. With that respect, a large fraction of gamma-raysources in the Galaxy remain unidentified, and protostellar jets are among candidates to be the hidden cosmic ray accelerators. It was very recently demonstrated that mildly relativistic shocks in the backflows in the lobes of AGN jets  can accelerate particles  up to the Hillas energy, offering a suitable environment for the acceleration of UHECRs. However, in order to account for the heavy composition of the UHECR spectrum, a jet mass loading mechanism is needed. At lower energies, acceleration of TeV particles in protostellar jets can be quenched by ion-neutral collisions, and therefore kinetic calculations are desirable in order to compute the maximum energy of particles in low velocity shocks and non-completely ionized plasmas.  I will investigate the maximum energy that particles can achieve when they are accelerated via DSA in  mildly-relativistic and low-velocity shocks, in AGN and protostellar jets, respectively. In the former case I will consider the shocks produced by the interaction of powerful stellar winds with the jets, whereas in the latter case we will consider the  jet termination shocks.  By performing unprecedented calculations with the a newly developed hybrid code, I aim to address the maximum ener
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Smart Integration of Waste and Renewable Energy for Sustainable Heat Upgrade in the Industry' (SUSHEAT) targeting Horizon Europe.

assistant: **Abstract**

SUSHEAT develops and validates, up to TRL 5, 3 novel enabling technologies: high-temperature heat pump (HT-HP), Phase Change Material (PCM) bio-inspired Thermal Energy Storage (TES) system, and Control & Integration Twin (CIT) system; for heat upgrade in top-level labs. It will attain an efficient heat upgrade up to 150-250 °C thanks to the use the innovative Stirling-based HT-HP, working with hellium and enlarging the industrial exploitability of heat upgrade systems, reaching a COP up to 2.8 for temperature ratios of 1.2. The integration of innovative TES will ensure a reliable, flexible, and customizable heat delivery with full decoupling from any waste heat recovery and renewables availability. Moreover, its CIT will provide user-friendly tools and a digital twin for the control system and advising industrial stakeholders, based on smart decision-making algorithms.SUSHEAT will bring an effective self-assessment of the most suited heat upgrade system integration including not only its key enabling components but, beyond, also leveraging on off-the-self RES-based units, particularly solar thermal collectors even enlarging the feasibility of Concentrating Solar Power systems that can extend its operation working at low temperature.Two case-studies are replicated for validation at TRL5, and 4 additional cases are analysed in-depth to cover other sectors as Pulp & Paper, Beverages, Petrochemical, Textile & leather and basic metals.By developing industry-focused self-assessment tools, and directly engaging different industrial stakeholders, SUSHEAT will contribute to identify the target industrial processes and sites which would benefit from the concept, rising awareness of various heat upgrade benefits within the industry and providing solutions to maximize the industria
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'VIbro-acoustics of PERiodic media' to be submitted under Horizon 2020.

assistant: **Abstract**

VIPER is a European Joint Doctorate network focused on research in VIbroacoustic of PERiodic media. Structural periodic design is a powerful strategy for lightweight structures achievements while remaining a convenient solution for manufacturing aspects. One of the research targets is the inclusion of vibroacoustic design rules at early stage of products development through the use of periodic media which exhibit proper dynamic filtering effects. In order to understand how periodic concepts can improve the broadband vibroacoustic signatures and performances, the VIPER project will develop and validate tools for the design of global vibroacoustic treatments based on periodic patterns allowing passive control of structural and acoustical paths in layered concepts. Dealing with large scale periodic structural-acoustic concepts involves a multi-scale aspect that needs specific numerical tools. A two scale strategy will be pursued to handle periodicity effects: the meso-scale, related to the cell or the span size, and the macro-scale related to the final structure size. Bridging the cell scale behavior and the vibroacoustic indicators is a challenging issue which will dramatically improve the macro structural design.As the cell topology and constitutive materials are important data, VIPER will consider the combination of different materials and structural arrangements, in which viscoelastic, poroelastic, auxetic materials will play a major role. Finally, this project will also address the lack of perfect periodicity which can be considered both in view of robustness and design analysis of proposed periodicity based concepts. VIPER has a multi-disciplinary character, coupling expertise from material science, vibration and acoustics as well as applied mathematics. It can offer