RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'HEAT PIPE TECHNOLOGY FOR THERMAL ENERGY RECOVERY IN INDUSTRIAL APPLICATIONS' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Energy-Intensive Industries (EII) in Europe are characterized by very high energy production costs as well as by an important level of CO2 emissions. Energy production costs account for up to 40% of total production costs in some EII, while EII emissions represent a quarter of total EU CO2 emissions. EII are therefore directly concerned by the EU 2014 Energy/Climate Package, which sets a global objective of 40% reduction of GHG emissions and 27% increase of energy efficiency by 2030.The report on energy prices and costs for some energy-intensive sectors published by the European Commission showed for example that natural gas prices for European ceramic companies increased by around 30% between 2010 and 2012 and they were four times higher than in Russia and more than three times higher than in the USA. Similarly, electricity costs were two times higher in the EU than in the USA and Russia. Such figures clearly confirm that energy is a crucial element for the competitiveness of our industry.Therefore, an integrated approach to process innovation is proposed within ETEKINA project covering design, simulation, operating conditions and process management together with breakthrough technology for waste heat recovery.The overall objective of ETEKINA project is to improve the energy performance of industrial processes. For this to be possible, the valorisation of waste heat by a turnkey modular  Heat Pipe Based Heat Exchanger (HPHE)  technology adaptable to different industry sectors will be addressed within the project and demonstrated in three industrial processes from the non-ferrous, steel and ceramic sectors in order to demonstrate:(i)the economic feasibility of the solution, and therefore(ii)its market potential.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'In planta jet injection: Efficient genetic engineering of resilient crops'.

assistant: **Innovation**

Feeding 11 billion people by 2100 in a changing climate is a global challenge. Without further innovation, predicted crop yield will decrease due to climate change effects. Moreover, the number of biotic threats is increasing with pathogen pressure and infection risk showing temperature-dependency as well. Thus, crop breeding must be invigorated to generate plants with higher yield, and climate change resilience needs to be urgently met. Genome editing has the potential to assist classical breeding. Breeding based on gene editing enables faster production of crops with improved traits such as drought tolerance, disease resistance, and increased yield. Established delivery methods for in planta crop transformation are labor-intensive, cannot be applied to any crop species and have low transformation efficiencies, often below 1%.Delivering genome-editing cargo efficiently and cost-competitive in vivo, through the hard plant cell wall, is an unmet challenge. With our approach we aim to generate affordable, high-throughput devices that enable fast and efficient transformation of crops. Thus, our scalable approach is compatible with mass production. This, in turn, will open the market for transgenic plants for newcomers leading to more innovation and competition that will drive food costs for the consumers and varied products.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Pathogenesis of autoimmune neurodegeneration: What causes the immune system to destroy healthy neurons?' (POAN), addressing dissemination and exploitation.

assistant: **Impact**

The goal of this research is to determine under which conditions an autoimmune attack on neurons can occur. There is a growing interest in neuroimmunology, and data suggests that disorders such as Parkinson’s disease and schizophrenia have an autoimmune component. The ideal disease for studying this phenomenon is, however, the sleep disorder narcolepsy with cataplexy (NC), where the hypocretin (hcrt) producing neurons in hypothalamus are lost. Genetic and epidemiological evidence suggest that the specific hcrt cell loss is caused by an autoimmune attack, but the trigger of this is unknown. As post doctoral fellow at Stanford Center for Sleep Sciences Dr. Birgitte R. Kornum has been involved in the discovery of two genetic associations in NC. This has implicated the P2Y11 receptor and DNA methyltransferase 1 (DNMT1) in the pathogenesis of NC and warrants further studies of these two proteins and their functions in the immune system and the brain. The overarching aim of the research proposed here is to study autoimmune destruction of neurons, and how P2Y11 and DNMT1 contribute to the pathological process. Autoimmune destruction of neurons is prevented by several mechanisms. Negative selection of autoreactive T cells occurs during T cell maturation in the thymus. This process is, however, far from perfect and T cells with reactivity towards neuronal targets are instead controlled by other less well-understood mechanisms. These include inhibition of T cell activity by regulatory T cells, suppression of MHC expression in mature neurons, and a higher resistance in neurons to apoptotic signals from T cells. The experiments proposed here studies P2Y11 and DNMT1 in these processes using in vitro and in vivo models. Studies of patient samples from the Danish Center for Sleep Medi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Mechanism for photochemical energy storage and conversion in extended systems' under Fourth Framework.

assistant: **Concept**

Research objectives and content In nature, the conversion of light into chemical energy involves extended conjugated molecules and the abilitiy of these chromophores to undergo cis-trans isomerization and to transfer energy on short timescale takes a prominent part in photochemical activity. The proposed project is to understand the energy redistribution in extended conjugated compounds, particularly by studying cis-trans isomerization i extended molecules and energy transfer in bichromophoric systems. By performing accurate calculations on smaller molecules and on models for real systems, we propose to explore the mechanism of energy transfer from excited state to ground state. The results of this work are expected to improve our understanding of photochemical reaction mechanism and give new insights into photobiological processes. There will be of fundamental importance in photochemistry and photobiology. Training content (objective, benefit and expected impact) This work programme will enable me to enlarge my knowledge in theoretical chemistry, particularly, by building up new expertise in Multi-Configurationnal methods and in hybrid quantum mechanic molecular mechanics. This work will also exploit and further develop my abilities in chemical reactivity studies that were gain during my Ph.D. work. Links with industry / industrial relevance (22)
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Development of a new rapid method for determination of microbial contamination using luminescence imagery' in the context of a Fourth Framework call.

assistant: **Objectives**

As far as health is concerned, consumers microbial infection can cause serious problems and sometime even death. For this reason a microbial control is a major stage during the production and before the delivery of liquid food products and consumer medical products to guarantee their sterility.The method used at the present time for the determination of microbial contamination are based on culturing petri dish which involved a necessary long time to obtain the results of the microbial analysis (1 day to 21 day). This fact had some incidence on the quality of the controlled product, production costs and economic values of perishable goods.The objective of the present research is to develop a set of apparatus and reagents which will allow microbial contamination control in less than few hours and which will detect rapidly a very low number of micro-organisms using new rapid method involving a low cost equipment for microbiology testing. It will meet the requirements of the industrial partners.A preliminary work has been done in order to define specification of the samples. A knowledge of the sample characteristics is necessary to define the first step of the project (task 1) to eliminate every particle that will prevent the filtration or some chemical components that will be inhibitors for luminescence reaction. SMEs partners brought samples that will be analysed by classical microbiological controls (cfu) and classical physico-chemical controls.The project is based on microscopic imaging of the intracellular ATP of different micro-organisms (such bacteria, yeast's or mycelium) fixed on a filter membrane.A bioluminescence reaction is used to visualise the ATP and the observation is carried out through a low noise integrating camera. The sensibility of the detection is hig
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Structural Studies on Influenzavirus Fusion' in the context of a Seventh Framework call.

assistant: **Objectives**

The fusion of biological membranes underlies basic cellular processes of vesicle transport as well as the infectivity of enveloped viruses. The haemagglutinin (HA) glycoprotein of influenza viruses mediates fusion between viral and cellular membranes at the pH of the endosome to deliver the viral genome into the cytosol. Despite its high surface variability, its fusion machinery is conserved among HA subtypes and is a prime target for broadly neutralizing antibodies. HA consists of the receptor-binding HA1 and the fusion-mediating HA2, which has two membrane-interacting elements: the N-terminal fusion peptide and a C-terminal transmembrane anchor. At low pH, HA2 undergoes a series of conformational changes that project the fusion peptide out of a protein pocket towards the target membrane, and subsequently bring fusion peptide and transmembrane anchor, and likely the two membranes, into close proximity. The conformational changes are defined by crystal structures at neutral and low pH, but the membrane-associated parts of the protein were absent from the crystallization constructs. To define their roles and interactions, I propose to solve the full-length structures of HA at neutral pH and of HA2 at low pH by x-ray crystallography using state-of-the art crystallisation methods. High amounts of detergent solubilized membrane protein can already be purified from virus. The crystallization process will be aided by biophysical protein characterization and electron microscopy. The structures will impact our understanding of the mechanism of membrane fusion and help develop broadly neutralizing antibodies as influenza therapeutics. The project will complement my previous training in the structural biology of soluble proteins to membrane protein specific methods, electron micr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Electric Field Assisted Dynamic MOF alignment and Crystal Assembly'.

assistant: **Concept**

Despite the staggering number of reports on Metal-Organic Frameworks (MOFs), we are still greatly limited in our ability to manipulate colloidal MOF particles and control MOF orientation. Reliable control of MOF crystal orientation is extremely important as the properties and functionality of most MOFs are highly dependent upon crystallographic direction due to lattice anisotropy. However, the effective exploitation of such functionality remains frustratingly out of reach.   Based on the novel concept of exploiting MOF anisotropic ion mobility and polarizability, DYNAMOF aims to establish a flexible toolbox of methods for both dynamic and static control over the orientation, alignment and deposition of MOF crystals, which can be integrated into other processing techniques, thus paving the way for major advancements in the performance of MOF materials, composites and devices.  The mechanisms of E-field alignment of MOF particles as well as colloidal interactions governing MOF plastic or liquid crystal assembly, non-classical crystal growth and oriented film formation will be studied to develop a comprehensive and revolutionary platform for orientational control of free-standing and supported MOF crystals. As a proof-of-concept, the implications of MOF alignment on the proton conduction of MOF composites will be tested to pave the way towards next-generation MOF proton exchange membranes.   This ambitious project, which straddles the disciplines of materials science, chemistry and physics, is expected to break new ground by removing a key barrier in our ability to manipulate MOF particles. The wider goal of DYNAMOF is to establish the principles and working methods for colloidal manipulation across a wide materials spectrum, by using MOFs as a versatile platform for expan
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Independent test of the battery health in electric vehicles' in the context of a Horizon 2020 call.

assistant: **Objectives**

Batteries are subject to degradation over time, which results in a decrease in available power and range of electric vehicles (EV).When buying a used electric car, it is therefore of great importance for buyers and sellers to know the exact state-of-health of the battery as this determines its value to a high degree. AVILOO developed the only existing independent, trustworthy and objective battery testing system for electric vehicles. The AVILOO b:check will bring evidence for the quality of batteries in used electric cars. The b:check is a radically new, breakthrough product opening new markets with the potential for rapid growth. AVILOO’s b:check will enable an independent and reliable battery check to receive an exact report on the actual state-of-health of any battery in any electric vehicle. The AVILOO b:check is applied during a simple test drive and therefore provides an exact result of the SOH. Current solutions are either commercially inefficient because extremely expensive, not accurate or not at all independent. The AVILOO b:check project focuses on the further development and market uptake of the AVILOO products and services. The objectives will be reached by continuous developing, optimizing, testing, demonstrating, and validating the AVILOO products and services. AVILOO will contribute to the plans and measures set by the European Union on tackling climate and environmental-related challenges within the Green Deal. AVILOO‘s b:check supports the acceleration of the shift to sustainable and smart mobility and a zero-pollution ambition for a toxic-free environment. AVILOO's b:check paves the way to avoid CO2 emissions by (1) inducing an extension of the lifespan of batteries used in EVs and by (2) allowing a so called second life usage for batteries not suita
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Women's Criminality in the Ottoman Literary World (1860-1922)' (1860-1922).

assistant: **Innovation**

This project sketches a broader framework for the characterization of women offenders, expression of women crime committing, and their involvement as both victims and offenders in criminal cases not only in fictional narrations of Ottoman literature but also in real cases that made news in the Ottoman press. I will critically address male-centric discoursing, repetitive imputations, stereotypical and cliché wordy choices, and reiterative vocabulary for the identification of female criminals by examining Ottoman newspapers, magazines, journals, and books from the late Tanzimat period (the 1860s) up to the demise of the Empire (1922). This work will mainly utilize feminist criminal approaches that follow iconoclastic ways to stand up against the systematic underestimation and negligence of androcentric crime theories and their effects on historical narratives. These all restrict women’s participation and involvement in criminal cases and identify female perpetrators without their criminal agency. As a part of this understanding, their voices as wrongdoers were mostly silenced in the Ottoman press and literary works. In this regard, this study will especially dwell on women offenders who committed offenses contrary to their vulnerable, fragile, and sensitive stereotypical features, all too frequently used as the reasons for the incapability of women to commit serious crimes. Succinctly, the major goals of this project are to analyze the perspective, vocabulary, wording, and conceptualization by the Ottoman press and intellectual productions in the narrations of women’s delinquency and the identification of criminal women’s agency through literary criticism and to raise the voices of Ottoman criminal women in real and fictional crime stories in the light of feminist crimina
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Sixth Framework proposal on 'Kinship and social security'.

assistant: **Innovation**

The state and the family (including the whole network of relatives) are the two greatest providers of social security in modern Europe. Like the state, the family provides care, education, financial support, and help in finding employment. It also influences (and occasionally controls) choices involving career and marriage. However the role of the family is not constant over time and space. We know, from statistical sources and from sociological and ethnographic studies, that it varies greatly between different parts of contemporary Europe. Changing patterns of marriage, cohabitation and divorce, declining fertility and aging populations, also have implications for the family's social security role. Though the role of kinship in social security has important implications for state and EU policy on social security, gender discrimination and social exclusion, it remains relatively little understood - despite challenging contributions in recent decades from anthropology, economics and evolutionary theory. One reason for this is that conventional data sources such as census and surveys do not collect the full range of data needed to evaluate these theoretical developments. The only sort of data that is capable of capturing enough factual detail about kinship networks, while also investigating the way these relationships are actually experienced, is ethnographic fieldwork. One of the central ideas of this proposal is to use ethnographic methods, followed by both interpretative and mathematical analyses of the resulting data to illuminate the questions above. The second central idea is that current trends need to be understood in their historical context. The fieldwork studies will be carried out in eight European countries and will be placed in context by reviews of existing