RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'The premium green multi-cloud management and optimization tool' in the context of a Horizon 2020 call.

assistant: **Objectives**

Feasibility study - NUVEA is carried out by the SME New Generation SR, an innovative start-up active in the field of digital technologies and infrastructures. The objective of the overall project is to bring to customers an on-line platform that allows them to take over, manage, benchmark and optimize permanently their distributed IT infrastructure (at the web- and entreprise-grade), independently from the underlying cloud resource provider(s), in a highly flexible and real-time manner.NUVEA targets cloud computing stakeholders: data center managers, cloud suppliers, big companies with significant in-house IT infrastructures willing to optimize their energy consumption and average server load;  public institutions wanting to have fully sovereign or close-to-territory IT infrastructure; and companies having a part of their core competencies cloud-hosted, or significant IT expenditures.A first version of the algorithm and interface was developed and successfully tested in a laboratory environment. The present feasibility study aims at assessing technical and economical characterics of NUVEA’s value proposition through alpha tests on early adopters and in depth market study. This work will enable: - The release of the first commercial version of NUVEA software (validated on “early adopters”),- The definition of technical specifications required for the  further development of NUVEA on-line platform (NUVEA platform)  - The elaboration of a detailed business-plan based on operational experience,- The identification of the preferred stakeholders for european deployment of the solution,- An updated project executive summary ready for the search of new equity.Phase 1 will help to finance scientific support and marketing expert required for the feasibility study Later on, Phase
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Assembly and host interactions of influenza virus polymerase in the living cell' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

Currently circulating highly pathogenic avian influenza virus strains (H5N1) could cause a devastating pandemic if they became transmissible between humans. Thus understanding of the mechanisms whereby influenza virus adapts from avian to mammalian hosts is of great significance. Recent studies have highlighted the importance for transmissibility of mutations in the viral polymerase - a trimeric complex possessing activities essential for transcription and replication of the viral RNA. The mechanism of polymerase assembly and the host factors involved are not clear yet, nor are the molecular functions affected by the mutations related to avian-to-mammal transmission. To clarify these and to complement the extensive studies of atomic resolution structure of the polymerase and its host-specific variants performed in the Host laboratory, we propose to investigate in living cells the intracellular trafficking, assembly and interactions with host cell factors of the human and avian variants of the polymerase subunits. State-of-the-art two-colour fluorescence cross-correlation spectroscopy (FCCS) and confocal microscopy techniques will be used to monitor these phenomena in a non-invasive way. The project is inter-disciplinary as it combines advanced cell biophysics with structural and molecular biology in order to address a very topical issue in virology. The results will contribute to understanding of the relationships between the atomic structure of influenza virus polymerase and its function in the infected cell. New insight into adaptation of the influenza virus replication machinery to mammalian hosts can be used to elaborate new strategies for development of anti-viral compounds targeting polymerase or its interactions with host cell factors. Pursuing this multidiscipli
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'A Genealogy of Corruption. Administrative Malpractice and Political Modernization in Eighteenth Century Wallachia' in the context of a Horizon 2020 call.

assistant: **Objectives**

The transition from the Old Regime to modern European states in the 18th and 19th centuries entailed a transformation in the meaning of “corruption”. While seen as a moral failure from Antiquity to the Early Modern period, with the separation of the public and private domains in the 18th and 19th centuries, corruption came to be strictly defined as the abuse of public office. Until now, this particular transition has been studied only in Western and Northern Europe and in North America, where the reduced level of administrative corruption came to be seen as part and parcel of successful state-building. Although corruption in Southeastern Europe has received ample attention, it has been mostly treated as a quasi-natural characteristic of the region, and completely ignored as a problem of governance. My project addresses this problem by scrutinizing the emergence of the problem of administrative malpractice in the long 18th century Wallachia. Based on archival and published sources (judicial decisions, regulations, chronicles, travelogues etc.), the project offers the first systematic study of the practices which can be called corrupt, of the discourses about corruption and of the reaction of contemporaries to this phenomenon. The importance of the project lies in throwing light on processes of modernization in Southeastern Europe prior to the adoption of the Western cultural and political model during the 19th century.


**Keywords:** corruption, patronage, modernization, state, administration, Wallachia
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Nanostructure formation during food protein digestion and influence on intestinal transport'.

assistant: **Objectives**

The global food system is currently facing great challenges, which are mainly motivated by environmental and health-related concerns: (i) The existing food resources are not efficiently utilized; while some of them are overexploited, causing water/soil shortage, biodiversity losses, etc., others are not properly valorized (e.g. seaweeds). (ii) Moreover, the unhealthy dietary habits of modern societies are leading to a dramatic increase in the incidence of diet-related chronic diseases (e.g. obesity, diabetes, etc.). In this context, the food industry is actively looking for ‘novel’ food sources with added health benefits. However, to design strategies for a sustainable production of nutritious food products from alternative sources and to predict their potential metabolic responses (e.g. satiety, allergenicity, etc.), it is essential to understand how food structure, digestibility and bioavailability are correlated.PRODIGEST seeks to investigate this topic from a novel perspective, focusing on the mechanistic and structural aspects of the gastrointestinal digestion of food proteins and studying their implications on bioavailability. The type of structures formed by the assembly of the digestion products through intermolecular associations or by interactions with physiological medium components, as well as the effect of dietary fibres (which are abundant in alternative protein sources) will be studied and linked to their intestinal transport and susceptibility to trigger metabolic responses. To address this challenge, a set of advanced structural characterization tools (including X-ray and neutron scattering techniques, peptidomic analyses and rheology), as well as intestinal transport studies, will be combined through a multi-disciplinary approach, interconnecting struc
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Nano- and microtechnology -based analytical devices for online measurements of bioprocesses' to be submitted under Seventh Framework.

assistant: **Abstract**

There is a growing need for effective monitoring of the micro-organisms and bioprocesses used in the sustainable production of fuels, chemicals and pharmaceuticals. The NANOBE -consortium will develop a compact, flexible analysis tool for reaction monitoring applications in the industrial biotechnology industry.    The result of the NANOBE –project will be an integrated measurement platform for real-time monitoring of industrial bioprocesses. This versatile platform will enable simultaneous analysis of dozens of analytes, including individual cells, product profiles and intracellular biomarkers.  The platform will be composed of multiple 'lab-on-chip ' modules. Together, these modules will measure a broad range of analyte types, including small molecules, proteins, enzymes, metabolites, specific mRNAs and entire cells.    The measurement platform will be a significant improvement in terms of automation, analysis time, identification and sensitivity. The analysis platform will permit real-time feedback control of large-scale production processes, screening of production organisms and optimisation of reaction conditions. The tool will improve process productivity, product quality and accelerate development of production organisms for applications in industrial biotechnology.  The platform is designed to be flexible so that it can be applied either as a multiplex platform system to monitoring multiple analytes, or as individual device components for analysis of specific compounds. The versatile measurement tool will require only a change in method (e.g. a change of reagents or analysis conditions) to enable the measurement of a new analyte.  The NANOBE consortium combines world-class expertise in microfluidics, nano- and microfabrication techniques, photonics, electronics,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Clearview Trade - Cloud based collaborative custom system' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Solutions to facilitate international transport and trade are growing in parallel with global BNP growth. The recent digitalization of customs is creating opportunities in this market. ClearView Trade’s cloud based collaborative solution and business model is positioned to disrupt and exploit the opportunities in the SME market and dedicated to open standards. Importers and exporters rely on manual or semi-manual processes to facilitate cross-border transactions, such processes are both inefficient and error-prone, and as a result, 40-50% of all customs declarations are incorrect. We are the first company to introduce a collaborative platform that supports the process from export to import end-to-end. Export and import declarations are based on the same data, and by enabling exporters and importers to share and re-use these data in a mutual system, we create substantial savings, especially for the SME segment. Based on our current experience, we reduce the exporters’ time consumption by 50-80%, this amount to € 2,5 to 10 pr. Shipment. Enables users to comply with the relevant standardsIntroducing cost savingsIncreases accuracy of trade, transport and customs dataEnhances supplier relations and offers real-time visibilityReduces delays of shipments and increases supply chain efficiencyIncreases supply chain predictability, accountability and securitySimple online interfaceAffordable solution – price model targeting SMEsTruly collaborative system where information are shared between all relevant shareholders.Besides the ability to reuse data globally, for less errors and faster transactions, exporters benefit from improving the level of service, customer satisfaction and delayed shipments, whilst reducing the number of incoming calls and emails asking about shipment, as p
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Personal Decision Support System For Heart Failure Management' under Horizon 2020.

assistant: **Concept**

1–2% of the developed world suffers from congestive heart failure (CHF), which is the most frequent cause of hospitalization in people aged over 65. CHF management involves medications, monitoring of fluid intake and weight, exercise and lifestyle modifications. Since most patients are elderly and suffer from co-morbidities, they have difficulty adhering to the management guidelines, which often leads to poor outcomes.The HeartMan project will develop a personal health system to help CHF patients manage their disease. Its core will be a decision support system that will provide personalised advice to the patients. Its first key feature will be evidence-based predictive models: a short-term model developed in the European project Chiron, and long-term models adapted to focus on modifiable parameters that can improve the patients' predicted outcomes. Its second key feature will be the delivery of the advice through a cognitive behavioural therapy based on cognitive dissonance. This is a proven approach that exploits the dissonance between healthy attitudes and unhealthy behaviours to improve the behaviours. It will be augmented by mindfulness exercises, which are expected to make the patients more receptive to the HeartMan's advice. The system will also feature advanced health devices and monitoring methods to understand the patients' physical and psychological state, and standard-based data management for wide interoperability.In developing the HeartMan system, a human-centred approach will be used. The resulting system will be validated in two trials, which will test its medical effectiveness and usability. The project will also have strong dissemination and exploitation. To ensure industry-standard robustness, the industrial partners will have key role in developing th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'AI and machine learning assisted development of greener formulations and pharmaceutical processes based on amorphous solid dispersions'.

assistant: **Innovation**

This proposal is bringing together R&I related staff by a complementary set of participating organisations that will use multidisciplinary technological approaches to provide a proof-of concept framework for designing and introducing greener practices in pharmaceuticals. Knowledge will be transferred around the core technical activity that will be the introduction of HME as a novel production method, based on AI-ML tools and supported by environmental assessment for greener pharmaceuticals.


**Keywords:** AI, machine learning, hot melt extrusion, green processes, sustainability, pharmaceuticals
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'The role of semaphorins and neuropilins in tumour angiogenesis' (SEMASNEUROPILINANGIO) targeting Sixth Framework.

assistant: **Abstract**

Very little is known about receptor family of plexins, neuropilins and their ligands the semaphorins, in cancer progression and neo-angiogenesis. There are over 20 different semaphorins and nine plexins that can interact with each other in various ways. This scenario implicates a complex signalling pattern, the evaluation of which has only begun. It has recently been suggested that semaphorins possess both attractory and repulsory effects, which most likely are mediated by specific adaptor molecules and receptor tyrosine kinases (RTKs). The evaluation of the inhibitory, as well as promoting, function of different semaphorins, neuropilins and plexins is of great importance, and may lay the framework for therapeutic applications of these molecules.This project is aimed at understanding the functional role and mechanisms whereby semaphorin and neuropilin signalling may regulate angiogenesis in pathological conditions, such as cancer progression with a specific focus on the down-steam signalling of the two receptors neuropilin 1 and 2. More specifically, the project will employ the highly effective lentiviral mediated gene transduction, as well as the novel technology based on haematopoietic bone marrow cells (TEMs) (De Palma 2003 and 2005). TEM cells will be transduced with the semaphoring/plexin/neuropilin of interest, which will then be injected into lethally irradiated mice, to allow for full engraftment of transplanted cells.By these means, the aim is to obtain chimeric animals bearing a bone marrow-derived cell population able to selectively target the expression of a tumour-arresting molecule into the tumour vasculature. We will also be able to use semaphoring and neuropilin knock-out mouse models for tumour studies in collaboration with Prof. Christer Betsholtz of t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'The Elementary Theory of Partially Commutative Groups'.

assistant: **Innovation**

The solution of Tarski's problems on the first-order theory of freegroups has uncovered deep connections between Model Theory, Geometryand Group Theory and served as a nexus and  motivation for manyclassical results in Geometric Group Theory and Theoretical ComputerScience.Just as the Tarski problems connected the theory of free groups withthe geometry of trees, our goal is to point at a new direction inGroup Theory and develop appropriate generalisations of the techniquesand results whose nature is based on the geometry of higherdimensional counterparts of trees and interplays with the theory ofpartially commutative groups, notably the theory of groups acting onreal cubings.We then shall apply these tools to approach fundamental questions inthe model theory of partially commutative groups: classify finitelygenerated groups elementarily equivalent to a given partiallycommutative group and prove decidability and stability of theirfirst-order theory.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Expecting Ourselves: Embodied Prediction and the Construction of Conscious Experience'.

assistant: **Concept**

This project (short name, XSPECT) aims to harness the emerging science of the predictive brain to deliver new insights into the nature, scope, mechanisms and (most importantly) the very possibility of conscious experience. The project thus explores and extends the vision of the brain as an inner engine continuously striving to predict the incoming sensory barrage. The key innovation is to consider this increasingly popular vision in the special context of embodied agents able to predict many of their own evolving states and responses – agents able to ‘expect themselves’. These crucial self-expectations span the interoceptive (targeting the internal sensory flows signaling our own physiological states, such as hunger, arousal, itch, and muscular and visceral sensations) and the exteroceptive (targeting the world, and our own behaviors as they might unfold over multiple scales of space and time). XSPECT explores the idea that such interacting states of complex, layered self-prediction hold the key to understanding much that is puzzling about conscious experience.The project is divided into three simultaneously active sub-projects. The first sub-project concerns relations between prediction, motor action, and experience. The second sub-project targets the role of interoceptive prediction in the construction of experience. The third sub-project considers ways in which more reflective forms of conscious experience (involving agency, selfhood, and the introspection of own experiential states) are further enriched by a spiraling array of socially mediated higher-level self-predictions.XSPECT will combine integrative philosophical argument, collaborative experimentation, and leading edge interdisciplinary research and discussion, leveraging two very successful but under-communi