RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'New siRNA Nanotherapy for Inflammatory Bowel Diseases, targeting Janus kinases'.

assistant: **Objectives**

Inflammatory bowel diseases (IBD) are the second most common immune-mediated disorders in Europe, affecting more particularly young people. The current therapies, including antibodies, show three main drawbacks: efficacy, tolerability and convenience. NEW DEAL solution will offer radical therapeutic progress for all IBD patients, thanks to the improved efficacy and increased safety of the specific JAK3 inhibition, which has been proven in clinics to be a target of great interest, the better tolerability of siRNA in term of immunogenicity and the good convenience with oral administration. To achieve this challenge, we will address three objectives: i) Specifically inhibit JAK 3 in a highly selective and safer manner by the mean of siRNA carefully designed and validated, ii) Deliver the siRNA therapeutic locally to the inflamed gut, by combining innovative nanostructured lipid carriers enabling their transport across the mucus, the intestinal barrier and the plasma membrane of the target cells, with polymeric capsules for protecting siRNA nanotherapeutics during their transit along the GI tract, thus allowing an oral administration, and iii) Promote the clinical translation and the future industrial transfer of this new clinical product, by addressing manufacturing, safety and efficacy evaluation at the late preclinical stage, to generate a Regulatory Submission Package and a Clinical Development Plan. The NEW DEAL project brings together clinical experts on IBD, leading scientists in nanomedicine, RNAi biology and immunology, innovative SMEs with a strong background in nanosafety, design of capsules and regulatory issues and an established pharma company with historic expertise on gastroenterology medicinal products. If successful, NEW DEAL will open new avenues for siRN
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Quantum-chemical modelling of paramagnetic defects at oxide surfaces' (1994-1998) targeting Fourth Framework.

assistant: **Abstract**

The proposed project concerns theoretical modelling using ab initio quantum-chemical methods of defects at oxide surfaces. Different types of defects will be modelled, for example point defects like interstitial atoms, vacancies or substitutions, and topological defects like kinks, steps and edges. Especially will F-centres be studied. In these, an electron is trapped and localized at the site of an anion vacancy, and due to the unpaired spin the defect is paramagnetic. The oxide systems to be studied are MgO, a-A1203 and different forms of silica, such as quartz. The computational methods will be periodic HartreeFock calculations, which makes ab initio calculations at 3-dimensional crystals or 2-dimensional surfaces possible, and perturbed-cluster computations, which is designed for calculations of local perturbations in a crystalline environment. Both methods have been developed largely at TODipIFM. The structures, formation energies, distributions and chemical activities of the various defects will be investigated and characterized by these methods. Spin densities will be calculated and comparisons will be made with experimental electron paramagnetic resonance (EPR) spectra. Training content (objective, benefit and expected impact) The group of Prof. Pisani is one the leading groups in the area of theoretical solid-state chemistry. Both the periodic HartreeFock and the perturbed-cluster" methods are state-of-the-art in the field. Important contributions have been given by this group for example in the understanding of the chemical and physical properties of semiconductors and mixed ionic-molecular crystals, and lately also in the elucidation of reaction mechanisms in solids and at surfaces. It is likely that the applicant will much benefit from working with Prof. Pis
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'fAcilitating Public & Private secuRity operAtors to mitigate terrorIsm Scenarios against soft targEts' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Ensuring public spaces safety while preserving the freedom of citizens represents a challenge for European societies. Soft targets like malls, stadiums or big events continue to face a variety of evolving cyber and physical threats. To secure public spaces and other soft targets requires an integral security approach and new concepts involving all the security actors along with private operators.APPRAISE aims to build on the latest advances in big data analysis, artificial intelligence, and advanced visualisation to create an integral security framework that will improve both the cyber/physical security and safety of public spaces by enabling a proactive, integrated, risk-based, and resilience-oriented approach. This framework will be designed to support the secured private-public collaboration and optimise the coordination of operations involving private security staff, private operators, and law enforcement agencies.APPRAISE will offer unprecedented capabilities to predict and identify criminal and terrorist acts and enhance the operational collaboration of security actors before, during, and after an incident occurs. Social, Ethical, Legal, and Privacy observatories bringing together LEAs, private operators, technology experts, psychologists, sociologists, and society representatives will ensure full conformity of the developed tools with current EU legislation and citizens acceptance, preparing the ground for successful exploitation. The consortium consists of world-class research centres, industries, SMEs, LEAs of different types (national police, municipal police, elite tactical unit) as well as private security practitioners and operators, coordinated by a large industrial company with a leading position in the security market. APPRAISE will demonstrate its solut
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'AUX-Variation - a corpus based study of AUX-Variation in Danish' under Seventh Framework.

assistant: **Concept**

The project deals with the AUX-variation in Danish using the LANCHART corpus of spoken language. The four empirical studies take a more holistic approach to the study of language use and variation by combining corpus linguistic and variationist sociolinguistic approaches with quantitative statistical methods. Using multifactorial statistical methods, it is possible simultaneously to investigate the impact of various intra-linguistic and extra-linguistic factors as well as possible interactions between these. The project will contribute to my scholarly development: (I) by improving my methodological competences, (II) by enhancing my research profile, and (III) by extending my professional network and thereby opening up for long-terms research cooperation.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Microcontact. Language variation and change from the Italian heritage perspective.' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

This project aims to add an important block to syntactic theory, by developing new theoretical tools to account for microvariation and change. The central idea is that change and microvariation are necessary parts of grammar, and that they are in fact constrained by Universal Grammar (Chomsky 1957 ff.); in order to understand them we need not focus on the starting point and endpoint of change only, but also on the process itself. Observing change in progress can offer insights into its causes and the mechanisms underlying it. We aim at getting snapshots of change in progress by examining endogenous, diachronic change and change in contact for a number of genetically and typologically related varieties. Between the end of the 19th c. and the 1920s, many Italians migrated to the Americas. After World War II, a third wave of migration took place: around 400.000 people left Italy between 1950-1960. Interestingly, most of these Italians did not speak Italian as their native language: they all spoke some “dialect”. With this term we traditionally refer to those Romance languages spoken in Italy that evolved from Latin, and are sister languages to standard Italian. When these immigrants moved across the Atlantic, their languages entered in contact with other Romance varieties, like Argentinian Spanish, Brazilian Portuguese, or Québécois French, as well as with English. The languages spoken by these 1st generation immigrants, who are now very old, are extremely important, as they potentially give a unique window into the mechanisms of language change in general, and of syntactic change in particular.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Surfing radio Waves to detect  liquId water in the solar systeM', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

In the near future a number of space missions will aim to study the icy Galilean satellites of Jupiter to detect subglacial liquid water, using radar sounders. To properly interpret the radar data, it is necessary to understand the dielectric properties of the icy shells of these bodies, as they control radar signal penetration and anomaly (i.e., water) detection. The current knowledge of these properties for the types of water ices believed to be present is limited, which would potentially produce incorrect interpretations of the radar data, thus risking the scientific goals of these missions. Based on extensive experience in characterizing the dielectric properties of planetary analogues, which led me and my group to discover the first extraterrestrial subglacial stable body of liquid water on Mars, we intend to develop new methodologies and protocols to create a groundbreaking knowledgebase that fills this critical gap. We will apply the first of its kind methodology for conducting dielectric measurements across a wide range of frequencies (including the challenging interval used by these radar systems) and temperatures representative of the different ice-forming environments, produce groundbreaking studies on the structural and chemical behavior of different ice types using CT microtomography and molecular dynamic modelling, and will create a wide-ranging dataset of the dielectric properties of non-terrestrial ices. Such pioneering and high gain research will allow to obtain the maximum benefit from missions such as JUICE and Europa CLIPPER. By the end of the project significant and fundamental progress will be made to properly perform dielectric measurements on icy planetary analogues, in the comprehension of the physics behind the dielectric behavior of water ice
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'Quality monitoring and quality assurance of freshwater and seawater aquaculture fish (Cyprinus carpio, Hypophtalmichthys molitrix, Clarias gariepinus, Dicentrarchus labrax, Sparus aurata)'.

assistant: **Objectives**

Foreseen ResultsThe outcome of this project will provide sufficient data for characterisation of nutritional value nad organoleptic characteristics of tested fish and would therefore give information for establishing reliable quality standards.Quality and quality standards in an area of primary importance for the European Community since there is a general effort of standardising the quality of every product that is being used within the European countries and / or traded among them. For this reason quality is a new important aspect in the international trade.The main objectives of the proposed work are :- Compare the biochemical composition of wild and cultured species and identify differences in compounds which may affect their nutritional value and / or organoleptic characteristics.- Study seasonal changes in composition in relation to dietary history and area of collection of fish.- Couple chemical analyses and instrumental texture measurements to organoleptic characterisation of the fish by taste panels, and finally study the spoilage patterns of fish under test identifying duration of storage for an acceptable product.The fish which will be tested include two marine species, the sea bass and sea bream, which are the main products of Mediterranean aquaculuture and three freshwater species common carp, which is a product of many European countries, as well as silver carp and African catfish. Fish of commercial size will be used throughout the project will be collected from selected farms.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'Health care system reform policy content and process in the Caribbean'.

assistant: **Concept**

The overall objectives are as follows:* To increase understanding of the impact on efficiency and equity of reform of selected policies relating to the financing, organization and structure of health care systems. * To produce information that will support the process of reform of health care systems in the Caribbean .* To strengthen the capacity of the Faculty of Medical Sciences, St. Augustine, Trinidad and the Faculty of Medical Sciences, Anton de Kom University of Suriname, to do research relevant to health care systems.* To foster closer long-term collaboration in health care system operational research between European health research institutions and the Faculties of Medical Sciences in Trinidad and Suriname.Expected OutcomeIncreased understanding of the impact on efficiency and equity of those policies relating to the financing, organisation and structure of health care systems relative to the contextual development of the system. It is expected that information will be produced to support the process of reform of health care systems in the Caribbean.The capacity of the Faculties of Medical Sciences, St. Augustine, Trinidad and Anton de Kom University of Suriname will be strengthened to do research relevant to health care systems, and long term collaboration in health care operational research between the European research institutions and the Caribbean/South American partners will be established.The project is divided into two phases:Phase 1:This phase involves study of influences on the historical development of health services in order to understand the nature of the health care system inherited at independence (or similar period), subsequent changes, and the current situation. Investigation will focus on demographic, epidemiological, political, social, econo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Semiconducting and Metallic nanosheets: Two dimensional electronic and mechanical materials' (SEMANTICS).

assistant: **Innovation**

We will develop simple, scalable methods to exfoliate layered compounds into monolayer nanosheets. These materials have exciting properties. Recently, graphene has taken the nanomaterials community by storm. However graphene is only one branch of a family of two dimensional layered compounds. Other examples include hexagonal BN, metal dichalcoginides such as MoS2 and metal oxides such as MnO2. We propose that all layered compounds can be exfoliated in certain solvents by the addition of ultrasonic energy. Such a method has not been demonstrated because the vast majority of solvents are unsuitable for this. We propose that suitable solvents can be identified by matching their surface energy to that of the nano crystal, rendering the exfoliation process energy neutral. This will open the gate to a wide range of nano-materials science and makes possible experiments that have been impossible using standard techniques. We will pick a set of layered compounds such as the semiconductors; hexagonal BN, MoS2 and TaO3 and the metals TaS2 and MnO2. We will learn to exfoliate these materials, studying the physics and chemistry of the solvent-nanosheet interaction. Once we can generate large volumes of highly exfoliated few-layer nanosheets at high concentration, we will study the physics of these materials. We will prepare free standing films of restacked sheets and polymer-sheet composites for mechanical applications. Thin films can also be studied as transparent conductors and capacitor dielectrics. Hybrid films can be used to devices such as photodetectors. Much more challenging will be the production of large quantities of monolayer nanosheets. We will learn to deposit nanosheets on substrates and measure their thickness and size with AFM. Semiconducting monolayers will be char
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Software-Defined Number Formats: Bridging the Gap between Performance, Accuracy, and Security' (SoftNum), addressing dissemination and exploitation.

assistant: **Impact**

All computing devices implement computer arithmetic as a core functionality. Nearly all computing devices moreover implement the same, standardized number formats in order to aid software portability. However, with Moore’s Law ending, we question whether it remains the best approach to achieve high performance and low energy consumption by applying the same standardized number formats for all applications. Among others, the Internet-of-Things (IoT) presents a proliferation of compute devices with a wide variety of functionality, among others in data sensing, data analytics, and inference of machine-learned models. Additionally, security mechanisms, which are essential for internet-connected devices, are compute-intensive workloads. We posit that each of these workloads will see improved performance and energy-efficiency from distinct, specialized computer arithmetic. The SoftNum Marie Curie Fellowship will explore how to make number formats, generally considered to be hard-wired functionality, software-defined. Software-defined number formats have the advantage of high performance, low energy consumption, and ensure sufficient while not excessive precision.  For instance, with SoftNum it will be possible to design a data sensing device that pre-processes data streams at the minimal precision possible to minimize energy consumption, embeds a watermark to prove ownership and origin of the data, all while achieving the required application-level accuracy. This project, if successful, will have a major impact on how we perceive the design of computing devices. It will create an unprecedented degree of virtualization of the core computing hardware, with an estimated system-level speedup of 50% and reduction of energy consumption by 70%. This novel proposition promises to acc
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Plants as sensors for standardization and calibration of controlled environment chambers' to be submitted under Horizon 2020.

assistant: **Abstract**

Research in plant biology & crop breeding conducted in controlled environment chambers (CECs) require that observed differences in measured plant traits between or within CECs are attributable to the imposed experimental treatment or breeding protocol rather than to heterogeneity and/or poor accuracy in the monitoring of different chamber environmental conditions. To date, no commercial product has been developed which tests standardization of environmental conditions within and between CECs of the same manufacturer or between different manufacturers. The cost per chamber of deploying a full artificial sensor network to test for homogeneity of CEC conditions would be thousands of euros per CEC; a prohibitive cost for users and manufacturers alike. This Proof of Concept grant will develop and commercialize the first plant-based sensor kit for standardization and calibration of CECs used in plant research, commercial horticulture and by the international plant breeding sector (BAYER Crop Science, MONSANTO etc.) at one tenth of the cost of an artificial sensor network and with equal or better environmental sensing capacity. Commercialization of PlantSenseKit will be via a license agreement to a commercial partner and involve comprehensive market research, competitor analysis, and further technological refinement of the PlantSenseKit protocol, prototype testing & development of a business plan. This Proof of Concept grant will have a positive impact on society and economic activities by improving the performance of infrastructure used in food security and climate change research and by providing new jobs for Ireland via commercialization of PlantSenseKit.