RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Development of new sanswich materials to improve the acousticl isolation of indoor faces' (1994-1998) under Fourth Framework.

assistant: **Objectives**

Acoustic isolation requirements from the Administrative Departments, try to preserve people health and protect them from troubles caused by the great number of noises which can introduce at people's home; but, many times, these requirements do not operate as a guarantee for people who must live in buildings which acoustic characteristics are not necessarily subjected to the Standards of each country. In fact. there are several kind of deficiencies which, due to different reasons, can not be covered by today's regulations; because of this, a great number of constructions and buildings are out of the Standards application range. Moreover, they can be found several new buildings which do not fulfill the minimun requirements stablished by the Standards. Due to these troubles, the goals of this project can be summarized as follows: to develop new Sandwich panels (faces or compund materials) of high acoustic features and small thickness so that they will be used as: a) coverings for walls and internal partitions which have not the enough isolation level (applicable when partitions do not reach required isolation levels or when they reach but are not enough to satisfy users privacy and requirements) and b) constructive elements for fixed and removable partition walls of high acoustic features.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Selective Electrochemical Reduction of CO2 to High Value Chemicals' to be submitted under Horizon 2020.

assistant: **Abstract**

This proposal will develop enhanced electrolysis devices enabling CO2 to be converted into high value chemicals.  Specifically this project will improve selectivity, efficiency and durability of electrochemical CO2 conversion into either carbon monoxide, ethanol or ethylene. The immediate focus will be on the highly economically attractive chemicals industry, with the long term goal of using this as a stepping stone towards the fuels industry. New catalysts, gas diffusion layers, and membranes will all be developed to improve performance in commercially scalable type devices.  Single site catalyst will be used to create high selectivity towards carbon monoxide production, whereas a dual catalyst approach will be used to produce ethanol.  Variations in morphology and surface structuring will be the key to eliminating side reaction in ethylene production The greatest novelty of this project will be to use modifications in the reaction environment to effect reaction selectivity. The hydrophobicity and pore size will be varied in the gas diffusion layer and anion exchange membranes and ionomers will be developed to improve performance.  The entire device will be comprehensively modeled from the quantum regime all the way to the complete device to relate macroscopic changes with catalytic improvements. Developments in both improved catalysts as well as optimization of reaction environment will allow for high CO2 conversion selectivity, (CO 90%, ethanol 80%, ethylene 90%) at high energy efficiencies (> 40%) and at high rates (> 200 mA/cm2).  A life cycle analysis will focus on electrical power and CO2 inputs as well as the specific products to discover the most effective market opportunities for this technology moving forward. In addition social acceptance issues will be inve
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Neuronal Alternative Splicing'.

assistant: **Concept**

Alternative splicing is the process by which multiple mRNA isoforms can be generated from one gene by differential usage of alternative exons in the mature mRNA.  It is a major mechanism by which higher vertebrates generate functional complexity of their proteome.  Approximately 95% of human genes are alternatively spliced and this process is especially abundant in the nervous system and crucial for proper regulation of neuronal gene expression.  Evidence comes from identification of mutations disrupting pre-mRNA sequences, required for alternative splicing, but not for protein coding that cause neurological disease in humans.  Moreover, mutations of some RNA binding proteins, with roles in alternative mRNA processing, also result in neuro-developmental disorders and widespread misregulation of alternative splicing.  With advancements of high throughput sequencing techniques our knowledge about the kinds of alternative mRNA isoforms and their abundance in different kinds of tissue is rapidly increasing.  However, our understanding of the functional consequences of neuron-specific alternative splicing is still very limited.  During my postdoctoral studies I have discovered that Hu RNA binding proteins are required for alternative splicing of pre-mRNA targets with important roles in neuronal development and function.  I propose to investigate the functions of individual protein isoforms that are translated from Hu-dependent alternative mRNA isoforms.  Initially I will focus on studying the functions of the isoforms of the Kif2a gene, which encodes a kinesin motor protein involved in neuronal cytoskeleton dynamics and intracellular cargo transport.  I will especially focus on understanding how Kif2a isoforms regulate development of axons and also the transport of cargo to
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'LysoIP based-lysosomal signatures in Parkinson's Disease'.

assistant: **Objectives**

Parkinson's disease (PD) is a progressive neurodegenerative disorder affecting 10 million people worldwide. No curative treatments are currently available, but only symptomatic ones. Emerging evidence highlights lysosomal dysfunction as a key mechanism in PD pathogenesis, with associated mutations in the LRRK2 and SNCA genes, both linked to lysosomal pathways. This proposal aims to identify common lysosomal biomarkers associated with PD progression. By employing the innovative LysoIP method, which enables precise lysosome isolation, we will analyse lysosomal profiles in two PD mouse models of LRRK2 and alpha-synuclein across different ages. Our objectives include (1) setting up and validating the LysoIP method in wild-type mice, (2) identifying potential lysobiomarkers in PD mouse models, and (3) validating these biomarkers in cellular models of PD. This project directly aligns with the EU Work Programme under Horizon Europe, which focuses on advancing our understanding of neurodegenerative diseases and accelerating the discovery of disease-modifying therapies. Identifying lysosomal biomarkers will not only improve our understanding of PD mechanisms but also support the development of novel therapeutic approaches targeting lysosomal dysfunction.


**Keywords:** Parkinson's Disease, lysosomes purification, protein trafficking, mouse brain, human iPSCs
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Innovation Activities to mature Turbulence Cancelling Technology for Light and Business Aircraft from TRL 6 to TRL 8 as Key Enabling Technology for the Future of Sustainable Air Mobility' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

Global studies show a rise in severe weather events, particularly storms and turbulence, increasingly impacting air traffic. These adverse conditions lead to fuel-consuming detours, higher maintenance costs, in-flight injuries, and an increased workload for pilots and Air Traffic Management, raising accident risks. Light and Business Aircraft are especially vulnerable due to their lower weight and typical operation in lower atmospheric layers where turbulence is more prevalent. Turbulence Cancelling is a break-through technology that reduces the adverse effects of in-flight turbulence by more than 80%. It mimics birds' natural turbulence mitigation, enabling aircraft to deliver smoother, more stable flights. Turbulence Cancelling has already proven effective in the European Ultralight Aircraft segment, providing credibility for its expansion into more regulated markets like certified Light Aircraft and Business Aircraft. The emerging Advanced Air Mobility (AAM) sector, focusing on electric aircraft for urban transport, will also benefit from TCS, particularly as aircraft operating in urban canyons are susceptible to turbulence. NASA has highlighted the importance of mitigating turbulence to foster public acceptance of AAM technology, making TCS a key enabler for the sector's success.The EIC Accelerator provides important funding for the innovation development in highly complex and regulated markets that cannot be reached otherwise. Our request for 2.1M € grant-only enables us to bring the Light Aircraft and Business Aircraft to TRL 8 and to become the world-leading company for Turbulence Cancelling, making the whole aviation industry turbulence-free and not be limited to only smaller bridgehead markets. Without EIC support, our groundbreaking and patented European Turbu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'A unique mobile optimised site that facilitates the recovery and restoration of deleted smart device files at the point of need, without the need for a desktop computer.', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

People lose data and cannot get it back; people also want to ensure data is deleted permanently (erased). Wehave achieved proof of concept for an innovative solution to recover deleted items from smartphones andtablets. Cloud Recovery is the only customer data restoration solution from Europe; the others are from China, India and theUS, but all of these solutions require a PC. Our project aim is topush the boundaries, and deliver a truly market disruptive SaaS (Software as a Service) data recovery solutionthat is solely cloud-based (where more data is stored), with data recovered and restored within 10 minutes, without the needfor a PC or Mac.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Sixth Framework proposal on 'Technological Results Exchange Network'.

assistant: **Innovation**

Given the recent signing of the Scientific and Technological Cooperation Agreement between Tunisia and the EU in June 2003, the project main aim is fostering the scientific, technological and innovation (STI) cooperation between Tunisia and EU in the Thematic Priority Areas mostly related with science and technology based industrial development, with a set of specific and practical actions in order to:- Improve STI visibility, mutual knowledge and information flow between Tunisia and EU in the fields of research, innovation and technology transfer related to the Thematic Priority Areas;- Contribute to the improvement of researchers and technologists mobility and foster EU-Tunisia STI institution cooperation;- Develop a Tunisian expertise on European Community STI instruments to support local institutions (organisations and enterprises) and act as multiplier for cooperation in R&D programmes and transnational technology transfer. To achieve the above objectives, STREN foresees the following activities:- The creation of a dedicated web site platform including 3 on-line interactive databases on EU and Tunisian STI results, resources and opportunities;- The organisation of 3 STI thematic workshop days dedicated to scientific and technological topics related to the main FP6 thematic area priorities and one large and high level conference dedicated to the STI cooperation topics;- The collection of a set of international best practices in STI initiatives;- The organisation of 3 trainings on STI management subjects and EU FP6 and a further expert exchange programme to complete the mutual knowledge of ERA System;- The establishment of a network of 10 Tunisian experts that can act as support desk for the creation of new STI projects and technology transfer initiatives among EU, T
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Estimation of human IMPACT in the presence of natural fluctuations' to be submitted under Fifth Framework.

assistant: **Abstract**

The project aims at developing, testing and disseminating generic decision support tools that can match technological advancements in environmental monitoring and facilitate interpretation of time series environmental data. The approach is novel in the sense that mechanistic models based on physical, chemical and biological concepts and theories are fully integrated with statistical methods.Objectives:The objective of the project is to introduce a new set of tools which will bridge the present gap between purely statistical analysis of environmental monitoring data and mechanistic environmental modelling based on biological, chemical and physical concepts and theories. The specific tools objectives are to:Match technological advances in environmental monitoring;Facilitate estimation of environmental impact in the presence of natural fluctuations in the environment;Bridge the gap between statistical data analysis and mechanistic modelling.Moreover these tools also aim to involve the following specific procedures:Time series decomposition methods in which a given series of environmental data is divided into two components respectively representing meteorologically-induced fluctuations and meteorologically normalised estimates of human impact;Significance tests that permit retrospective impact assessment in the presence of co-variates representing natural fluctuations;Model reduction procedures that facilitate merging of statistical and mechanistic approaches.Work description:Tools development facilitating interpretation of time series of environmental data is divided into three types of activities:Development of generic computational procedures that can bridge the gap between statistical analysis of environmental monitoring data and mechanistic modelling based on physical
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'High performance intelligent Bottle Bore Tool for machining of the engine drive shaft' (BBT).

assistant: **Concept**

The development of the new Ultra High Propulsive Efficiency (UHPE) engine architecture includes significant changes in the configuration and functioning scheme compared to current technology for the aircraft engines. A main change is the addition of a gearbox to decouple the fan and the turbine rotation, resulting in new requirements for the main turbine shaft (increased RPM and decreased torque); these aspects involve new size and shape needs for this shaft that challenge the current manufacturing methods to achieve an internal bottle bore geometry with Length to Diameter ratio above 30 and length over 2 meters. At this point, the proposal covers the development of new tooling systems to perform the machining of the shaft with the required precision and quality.The main objective of the BBT project is to develop an intelligent tool concept for the internal profiling of the engine drive shaft integrating different technological subsystems that enable the achievement of large Length to Diameter ratio and meeting the aeronautic requirements related to the machined surface condition.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Light-Responsive Adhesives for Debond-on-Demand Solutions' under Horizon 2020.

assistant: **Concept**

Adhesives that debond-on-demand through application of an external stimulus are highly relevant for manufacturing (semiconductor, automotive, aerospace, construction, packaging, sportswear), healthcare applications (wound dressing, transdermal patches), and numerous other domains, and they can significantly contribute to the sustainable use of materials (repairing, reworking, recycling). In all cases, there is a technological need for effective and environmentally benign solutions that provide secure adhesion during use, while also permitting for a simple and clean separation of bonded parts “on command” without the need for additional complex process steps.The proposed project aims to develop new debond-on-demand adhesives based on the combination of low-molecular weight functional polymers and light-responsive degradable cross-linking agents. The new materials are expected to combine optimal adhesive properties for a wide range of substrates with a new mechanism that enables straightforward and efficient, ultraviolet light-induced debonding at ambient temperature. The debonding mechanism involves two different effects that are combined in a synergistic manner: the controlled degradation of the cross-linker transforms polymer networks into low-molecular weight polymers, and the simultaneous release of nitrogen gas “propels” the bonded parts away from each other. The degraded polymer residues can be easily removed and clean debonded components are furnished. The overarching goals of the proposed project are to bridge the gap between scientific discovery and implementation by (i) providing a better understanding for the mechanism at play; (ii) demonstrating the effect in a variety of adhesive platforms based on polymers that are employed in current adhesive technologies;
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Chemical Structure, Photo Physics and Emission Control of Single-Photon Emitters in Two-Dimensional Materials' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Single-photon sources are the foundation of quantum optical technologies, including quantum communications, computing and metrology. Since the first demonstration of single-photon emission from sodium atoms in a low-density atomic beam in 1977, this nonclassical phenomenon has been observed in various types of solid-state zero-dimensional (0D) and one-dimensional (1D) materials, such as single molecules, quantum dots, nitrogen-vacancy centers in diamond, silicon carbide, and carbon nanotubes.Very recently, a new class of single-photon emitter has emerged based on atomically thin two-dimensional (2D) materials, such as semiconducting transition metal dichalcogenides  and hexagonal boron nitride monolayers. These novel single-photon emitters are due to the generation and recombination of  excitons that are spatially localized by natural defects in 2D materials . Bright and stable light emission from these defect excitons occurs at photon energies below the delocalized exciton emission and thus exhibit ideal nonclassical single photon characteristics. Furthermore, their intrinsic presence within atomically thin 2D materials brings the advantages of the unprecedented materials compatibility and processing flexibility associated with this materials paradigm. In particular, the defects in 2D materials can be located at desired positions with atomic precision suggesting the potential to build extended quantum emitter networks. These promising properties offer a new path to the scalable integration of high-quality quantum emitters in quantum optical technologies. However, the research of 2D quantum emitters (2DQEs) is just at an early stage with many open questions about their fundamental properties, including their chemical and electronic structures and emission control. The a