RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Temporal Dynamics of Transient Attention' in the context of a Horizon 2020 call.

assistant: **Objectives**

To identify a target in a dynamic environment, attention must be allocated to the target’s at the right time. Temporally selective attention allows us to discriminate a briefly presented target from temporally adjacent distractors. However, when a target is closely followed by a distractor that shares the target’s response category, participants often erroneously report the identity of the distractor (distractor intrusions). Previous studies showed that such distractor intrusion effects are mediated by attentional processes, but the exact underlying mechanism remains a matter of debate. The proposed study is designed to fill this gap, using behavioural and electrophysiological measures.  We will test a new account of temporal attention and distractor intrusions. To do so, we will develop a novel paradigm that will allow us to track electrophysiological biomarkers (N2pc component) of attentional processes, separately for trials where participants correctly identified the target and intrusion trials. Prof. Eimer is one of the leading researchers in the field of cognitive electrophysiology. Under his supervision, I will train in state-of-the-art EEG and eye-tracking methods, and learn the skills required to become a PI. The studies are expected to have a substantial impact to several theoretical debates. Thus, the success of the action and its dissemination promises to turn me into a strong player in the field. From that standpoint, I will be able to find fruitful collaborations, especially by capitalizing on Prof. Eimer’s network of collaborators. As advancements are introduced to the field of cognitive psychology, researchers are rightfully expected to be apt in interdisciplinary methodologies, and especially in neuroimaging techniques. Training in these methods and achi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Single European employment market-place' (SEEMP) targeting Sixth Framework.

assistant: **Abstract**

Public Employment Services (PES) are becoming more and more important for Public Administrations where their social implications on sustainability, workforce mobility and equal opportunities play a fundamental, strategic importance for any central or local Government. EURES is the most integrated" system for building a single pan-European e-Employment market, but its underlying present and envisaged architecture seems not fully respondent to EIF recommendations namely on organisational, semantic and technical perspectives.The mission of the present SEEMP (Single European Employment Market-Place) proposal is to design and implement in a prototypal way an interoperability architecture for public e-Employment services which encompasses cross-governmental business and decisional processes, interoperability and reconciliation of local professional profiles and taxonomies, semantically enabled web services for distributed knowledge access and sharing.The SEEMP project will develop an EIF-compliant federated architecture and interoperability middleware as well as applicative plug-in services to allow existing National/Local job market places and data warehouses to be interoperable at pan-European level by overcoming state-of-the-art limitations. On top of this ICT interoperability infrastructure, SEEMP will develop knowledge discovery-mining services for cross-governmental (CG) decision and policy making support (CG-DS).The verification and validation for the SEEMP approach will be performed on an existing PES integration test case led by Agenzia Regionale per il Lavoro Regione Lombardia in Italy and FOREM in Belgium Wallonia, integrated by an additional scenario for EURES interoperability. Specific requirements, generalisations and assessment activities will be performed for
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project '2 for 1: Quantum Dynamics of Singlet Fission' (2for1-SingletFission).

assistant: **Concept**

The generation of renewable energy is of paramount importance as we move toward a low carbon economy. Solar cells represent a partial solution to this problem, and there has already been significant uptake of these technologies globally. In the proposed project we will study a quantum mechanical process which occurs in organic semiconductors called singlet fission (SF). Put simply this process involves a molecule absorbing a photon, and the resulting electron-hole pair ‘sharing’ its energy with a neighbouring molecule, to produce two electron-hole pairs. As such, SF has the potential to double the electrical current generated by these molecules from sunlight. While it has been studied since the 1960s, new experimental techniques developed in the host laboratory have recently lead to breakthroughs in our understanding of SF. The aim is of this project is to understand the intricacies of SF so that it can be exploited to achieve dramatic increases in device efficiencies. This will be achieved using a two-pronged approach to the problem. The first is the use of newly developed ultrafast spectroscopic techniques to understand the fundamental aspects of SF. The host group is world-renowned for using spectroscopy to produce breakthroughs in our understanding of organic electronics and quantum chemistry. The second will leverage the applicant’s background in physical chemistry to engineer SF systems with control on a molecular length scale. By combining these two innovations the project is expected to produce important results for the research community. These results will enhance our understanding of SF, with a view to exploit the process in real-world devices. We will elucidate the vibronic nature of intermolecular electronic processes with an unprecedented level of sensitiv
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Quantum mechanics according to a pragmatist transcendental approach: study of the universal or relative nature of the means of knowledge in microphysics' will create measurable scientific, societal and economic impact aligned with Sixth Framework.

assistant: **Impact**

This research project aims at clarifying the origins, the statute and the role of the means of knowledge used in the research activity of microphysics: the instrumental means (i.e. the measurement apparatus), the sensorial and conceptual means enabling us to perceive the measurement outcomes and to refer to them, and the mathematical means corresponding to the formalism of quantum mechanics, which enables us to predict (statistically) and interpret the measurement outcomes.The objective is to determine, for each of these means of knowledge, if it is universal (i.e. valid and relevant in the context of every possible research activity) or relative to a specific research activity (the one of microphysics). This research will contribute to improve our understanding of the physicists activity (pragmatist dimension) and to identify the a priori elements the physicist introduce in their knowledge of the world (transcendental dimension).For conceptual clarity, a distinction will be made between the experimental event (e.g. the shift of the pointer on the apparatus) and the physical event, which corresponds to an interpretation of the experimental event (e.g. a physical quantity having a definite value at a given time).In order to structure this research, the following questions will be examined one by one:- Do all the possible measurement apparatus, in principle, produce a well-defined outcome?- Is the Kantian transcendental aesthetic locally valid in the case of the perception of an experimental event?- In which respect can a physical event, occurring at the end of a measurement process, be called a classical event? And- For each component of the formalism of quantum mechanics (i.e. the vector spaces, the complex numbers, Schrodingers equation, etc.), is it possible to reform
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'DNA-protein crosslinks: endogenous origins and cellular responses.' (DNAProteinCrosslinks) targeting Horizon 2020.

assistant: **Abstract**

This project aims to address the most pressing questions in the emerging field of research on DNA-protein crosslinks (DPCs) and their repair. Covalent DPCs are highly toxic DNA lesions that block virtually all chromatin processes. DPCs are induced by various exogenous and endogenous agents, but dedicated repair mechanisms were unknown. It was previously assumed that DPCs are repaired by canonical DNA repair pathways. This has changed with my recent discovery of a specific and conserved DPC repair mechanism. I established that proteases of the SPRTN family degrade the protein components of DPCs, which maintains genome stability and ensures tumour suppression. Strikingly, DPC repair by SPRTN is essential for cellular viability, which suggests that cells are constantly challenged with substantial amounts of endogenous DPCs.I hypothesize there is an entire unexplored pathway regulating protease-based DPC repair and that DPCs are key drivers of endogenous genome instability. I will employ genetic screening approaches and develop novel functional assays to systematically define the components and working principles of this novel DNA repair pathway in mammalian cells. I will determine how DPCs are detected in a chromatin context, how different repair activities are coordinated and connected to cellular processes such as replication or transcription. Moreover, I will identify the currently elusive origins of endogenous DPCs, by investigating the essential role of the SPRTN protease.My results will not only provide insights into an essential cellular quality-control mechanism but also unravel processes causing genomic instability in human cells. Importantly, many chemotherapeutics used in the clinic exert their cytotoxicity by inducing DPCs. My results will thus have imminent im
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'The in vivo roles of tRNA modification' under Seventh Framework.

assistant: **Concept**

tRNA molecules are key in translating the genetic information into a protein sequence and critical for all aspects of cellular metabolism. Interestingly, tRNAs carry a plethora of chemical modifications, thought to regulate their function. Many of these modifications are evolutionarily highly conserved, and some linked to human degenerative diseases and cancer. However, we know little about their in vivo function and the mechanisms of how aberrations in tRNA modification lead to cellular phenotypes.Thus, my proposal aims at gaining mechanistic insights into the in vivo function of tRNA modifications by performing a comprehensive systems analysis of tRNA modification pathways in yeast: First, I will identify transcripts, which are abnormally translated in tRNA modification mutants, thus causing the observed phenotypes. Importantly, I will define the codon signatures that are the underlying cause. Second, I will develop a mass spectrometric LC-MS/MS-based workflow, allowing for a quantitative and sequence specific analysis of RNA modifications, which is currently not done in Europe. Third, by combining population analyses and long-term evolution experiments, I will address how tRNA modifications constrain the evolution of genomes and modulate cellular stress responses.To achieve my goals, I will combine novel technologies and genetics in an unprecedented manner to push the limits of our understanding. I will employ ribosome profiling, a novel method, that provides high-resolution snapshots of the translatome. I will use quantitative RNA mass spectrometry to establish the link between tRNA modification and changes in translation. Finally, I will use quantitative protein mass spectrometry to verify the translation effects of tRNA hypomodification at the proteome level.Taken
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'STATIONARY APPLICATION OF A PEM FUEL CELL FED WITH WASTE HYDROGEN' (1994-1998).

assistant: **Concept**

The objectives of this project is to demonstrate the feasibility of a PEM Fuel Cell for generating electricity from waste gases from an industrial process. The power unit is targeting to produce a 200kW net power and is based upon a 240 kW PEM stacks. The consumption of auxiliaries for operating the power unit have an estimated power of 40 kW. Reliability, safety and economics of the system and more peculiarly of the air compression system and hydrogen feeder are emphasised in order to provide the complete system with low maintenance operation and costs.The industrial process is the AIR LIQUIDE liquefied hydrogen production plant located in Wazier, North of France, which, in normal operation is venting some gaseous hydrogen to the atmosphere without recovery. The idea is to fed the PEMFC with some of this wasted hydrogen. The D.C. current is converted to standard A.C.current (250KVA, 50Hz, 400 Volts Tri.) used to supply some equipment of the plant.Technical results :- achievement of a european technology prototype of a 200 kW stationary power plant using PEM fuel cell, connected to an industrial process- use of waste hydrogen as the fuel for a PEMFC- use of a high efficiency (50% converter (fuel cell) incorporated in a maintenance free system (maintenance lower than 1 day/year)Commercial and markets results :-Diffusion of the results to the first market : chlore alcali industry (which produce waste hydrogen at a energy level of 13 Nm, corresponding to a potential production of 13000 MW of electric power) after that first step, we will target the second market : Petroleum refineries, ammonia plants, hydrotreaters and hydrocrackers,...The innovating aspects are :- implementing of an european PEM fuel cell at a power level of 200kW for a stationary application - use of tha
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Optimization of noninvasive assessment of the substrate for atrial fibrillation', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Due to population aging , the incidence of atrial fibrillation (AF) increases tremendously. Although not lethal, AF reduces exercise capacity and strongly increases the risk of stroke. Despite significant progress in understanding the pathophysiology of AF, its treatment is still far from satisfactory. AF is a progressive disease. With time, paroxysmal AF becomes persistent, and the success rate of therapies declines. The progression of AF is related to a slow but steady process of remodeling in the atria, characterized by hypertrophy, replacement of muscle cells by connective tissue, and changes in gap junctions. The complexity of the propagating activation wavefront in the atria is a good measure of the disease stage. Current methods try to infer this complexity from frequency analysis. A truly spatio-temporal quantification of wavefront complexity requires invasive electrophysiological investigation. For broad-scale clinical practice, a noninvasive assessment from surface electrocardiograms (ECG) is needed. Our group is running an ambitious clinical study in which high-resolution ECGs are compared with invasive electrical data in the same patient. We propose to augment this study with computer modeling to provide insights in the relationship between disease states and ECG parameters. State-of-the-art methods will be used to compute propagating activation in 3-D models of the atria in different stages of disease. Using a realistic torso model, surface ECGs will be computed from the propagating activation, and the relation between wavefront complexity in the atria and spatial complexity of the ECG will be investigated. The model will be validated with our clinical and experimental data. As a result of this work, we expect to optimize diagnostic methods and choice of tr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Ovid as Historian. The reception of classical mythology in medieval France and Spain', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Ovid –the classical Roman poet of love and mythology– became an immensely influential literary figure in Western Europeduring the 12th and 13th centuries. Due to his versatility, ambiguity and multi-generic poetic creativity his readership onlykept growing towards the Renaissance, although this demanded a number of different reading strategies (or excuses), bestknown through the French adaptation of the Metamorphoses, Ovide moralisé (14th century). But allegory and moralizingwere not the only medieval appropriations of Ovid's myths.The present project aims to bring the historical and literate reception of the Metamorphoses and the Heroides into thediscussion. Reading Ovid’s classical mythology ‘at face value’ or as a part of history was, in fact, a substantial part of themedieval engagement with the Roman poet. Two major works of vernacular historical writing actually use Ovid’s texts in thismanner: the Castilian General estoria (compiled 1270-84), and the French narrative of the ancient world, the Histoireancienne jusqu'à César (14th cent. version). The three vernacular texts and their similar appropriation of Ovid need to be studied together. This comparative, multilingualand transnational approach is another innovative aspect of the proposal. Breaking out of nationally defined researchtraditions requires a new intellectual framework which will be provided by the Danish-English Centre of Excellence, theCentre for Medieval Literature (Odense and York). The project fits perfectly into the European agenda of CML which dividesits research into three main strands: fictionality, languages, and canon. The present proposal will draw on, and contribute to,CML in all three areas: studying literature that crosses languages (Latin, French, Castilian), theorizing both the medieval
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Isobone: a tissue engineered living bone equivalent' (ISOBONE).

assistant: **Concept**

Objectives and content:The aim of the project is to develop living tissue-engineered bone substitute materials that can replace load-bearing and non load-bearing bone. The proposed material comprises autologous human tissue that is cultured in a three-dimensional biodegradable polymer scaffold, based on starch blends in the case of load-bearing bone, and on PEO/PBT copolymers in the case of non-load-bearing bone. In this project, a hybrid technology will be developed through a combination of biotechnology (development and characterisation of bone cell culture systems) and material technology (development of three-dimensional biodegradable polymeric matrices that facilitate bone cell growth and have similar mechanical properties to either load-bearing or non load-bearing bone). This hybrid technology will allow the production of a laboratory made tissue-engineered living bone equivalent that will exhibit similar mechanical, chemical and biological properties to normal human bone tissue. This novel technology is therefore expected to diminish the shortcomings of all current artificial bone replacement materials.The consortium is composed of 7 partners that are specialised in, respectively, cell culture techniques (ISOTIS B.V.), starch-based polymers (Novamont SpA), PEO/PBT copolymers (Twente University), non-conventional processing techniques for polymers materials (Cinpres Ltd.), designing techniques in polymeric matrices (Brunel University), material characterisation techniques and polymer bioactivity enhancement (INEB), and compounding and processing techniques of bioactive polymer composites (University of Minho).BE97-4612