RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Slow relaxation phenomena in nonlinear systems with breathers' demonstrating excellence, impact and implementation quality for a Fourth Framework call.

assistant: **Abstract**

Research objectives and content The slow relaxation phenomena observed in glasses are usually interpreted by the existence of many metastable states. George Tsironis and I have recently shown that nonlinear systems without metastable states, may also exhibit similar behaviours. We have also shown that this unexpected feature is essentially a consequence of the property that these systems can sustain long life time breathers (Nonlinear Localized Excitations) which play a role similar to those of metastable states. On the base of the new developments of the theory of breathers to which I participated actively, I propose to collaborate with the group of George Tsironis in Heraklion for performing a detailed analysis of the phenomena in 1 and 2 dimensional models. We shall analyse its consequences on the thermal transport and the dynamical response function of these systems. We shall also study the possibility of defining extended diffusion equations (similar to those used for porous media) which could describe these phenomena. The connection with the famous FPU (Fermi-Pasta-Ulam) numerical experiments showing a poor thermalisation in some anharmonic systems, shall be also investigated. We shall also study the possibility of realizing real experiments exhibiting such slow thermal relaxation for example by probing as a function of time, the relaxation of a thermal grid in appropriate anharmonic materials created by the interference of two short laser pulses. Training content (objective, benefit and expected impact) I have been recently involved in the recent breakthrough on the theory of breathers (existence proof in large classes of anharmonic models and other rigorous results). I collaborated recently with George Tsironis for the initial stage of this program. The purpose
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Epigenetic, neural and cognitive memories of traumatic stress and violence'.

assistant: **Concept**

MemoTV investigates the mechanisms through which stressful experiences shape memories in humans on epigenetic, neural and behavioural/cognitive levels. We will explore how these memories interact with cultural settings in ways that result in malfunctioning and mental suffering. Frequent exposure to the severe stressors associated with domestic and organised violence leads to the detrimental conditions associated with extreme and traumatic stress. Such exposure reorganises the functioning of the brain and mind in a lasting, self-perpetuating manner so that even very subtle cues, sometimes merely arising from imaginative processes alone, can continuously activate a corresponding stage of the defence cascade.We will investigate survivors of organised and domestic violence in different cultural settings: the German trauma clinic, Rio de Janeiro’s favelas, the townships of South Africa and a Burundian peace corps. Specifically, with regard to violence and trauma, MemoTV's ultimate goal is to identify the psycho-physiological mechanisms that lastingly alter the functional organisation of brain and mind. As means for suggesting methods to prevent and potentially reverse the consequences of maladaptive plasticity, MemoTV focuses on the exposure to and exertion of violence: (1) These extreme and intense stressors are thought to produce lasting changes. Reversing clinical symptoms and improving psychological functioning through treatment provides the detection of causal mechanisms. (2) The applicant’s group has demonstrated international leadership and expertise in field work in war-torn crisis regions. (3) The detection and influence of the mechanisms that govern the cycle of violence and adversity is a highly relevant societal topic.With its bold attempt to redefine the mind an
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'A large-area detector for precision time-of-flight measurements' (TORCH).

assistant: **Concept**

We propose to construct and prototype an innovative high-precision time-of-flight system suitable for large areas, up to tens of square metres. The TORCH (Time Of internally Reflected CHerenkov light) detector provides a time-of-flight measurement from the imaging of photons emitted in a 1 cm thick quartz radiator, based on the Cherenkov principle. The photons propagate by total internal reflection to the edge of the quartz plane and are then focused onto an array of Micro-Channel Plate (MCP) photon detectors at the periphery of the detector. A timing resolution of 15 ps per particle can be achieved over a flight distance of 10 m. This will allow particle identification in the challenging intermediate momentum region, up to 20 GeV/c. The TORCH detector is highly compact, and the technique will have wide-ranging use in particle and nuclear physics experiments, and especially those where space is at a premium.The work involves a number of ground-breaking and challenging techniques. We will develop ultra-fast Micro-Channel Plate (MCP) photon detectors that can survive for several years in high radiation environments. The MCPs will be procured in industry to our specification with customized active area and granularity. We will also develop state-of-the-art electronics to read out the MCPs with picosecond precision. Photon imaging will be achieved with milliradian resolution over the large optical volume of the TORCH.Whilst the TORCH detector has its primary application in the field of particle physics, the MCP and optical developments will also have applications in space physics, nuclear physics, as well as medical imaging.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Molecular machines with mechanically-controlled magnetic properties' (2002-2006).

assistant: **Innovation**

The proposal concerns the construction of ' molecular-based machinery' wherein mechanical movement within the molecule may control intermolecular magnetic interactions promoted by external stimuli. The molecular entities will be of the  rotaxanes" family which are molecules where a macro cycle is locked onto a linear " thread" by bulky " stoppers" at either end of the thread. Two types of rotaxane systems are proposed. The first involves a rotaxane where the stoppers are paramagnetic metal centers and the ring may either contain a stable organic radical or not. In this system, the thread portion will only have one position that the ring may occupy, and will be able to undergo photo-induced cis/trans isomerism. In the trans form there should be no interaction between the metal centers, whereas in the cis form they will be brought into close proximity with one another and will magnetically interact. If the ring does not contain a radical then the system will be a "light induced on/off magnetic switch", however, if there is a radical on the ring then there is a third state attainable by a second stimulus, namely a switch between a three-spin system to a two spin system. All these species will be identifiable by EPR. The second type of rotaxane system proposed will have a thread with two "docking sites" for a radical containing ring and heterometallic stoppers. An external stimulus will control whether the ring is sitting at one end of the rotaxane or the other. The magnetic interaction, and therefore the magnetic properties, will be different in either situation and may also be detected and studied by EPR. Therefore this system will be a case of a "two-state" switch promoted by external stimuli. The main outcome of this proposal will be innovation in the development of ' m
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'The effects of radiation on biomolecular clusters: fragmentation and reactions incited by proton impact at velocities close to the Bragg peak' (2002-2006) targeting Sixth Framework.

assistant: **Abstract**

The effects of ionising radiation on biological material have been studied on the tissue scale for many years. However, research to understand the processes at a molecular level has begun only recently. Relatively few experiments have been carried out on t he effects of ionising rays on key biological molecules (biomolecules) such as DNA and its constituent bases. Cross-sectional results for these interactions are highly relevant to the use of radiation in medicine.Today, it is possible to isolate biomolecul es including uracil, thymine, and adenine (bases of RNA and DNA) in the gas phase. Further techniques have recently been pioneered at the Institut Galilee, Paris to produce and characterise clusters of these molecules. The IPM group are currently developin g an experiment comprising an original double mass spectrometer and a cluster source which incorporates these new techniques. This project will initially focus upon the completion of the experimental system.The apparatus will be used to study the consequen ces of high energy proton impact on a biomolecule surrounded by a fixed number of water molecules. The experiment thus represents a novel perspective spanning two traditionally independent research areas: radiobiology and the study of gas phase molecules. Biomolecule - water reactions initiated by the impact of high-velocity ions will be observed for the first time, providing important new quantitative data. Experiments will be carried out for proton impact velocities of the order of the Bragg peak (c/137). A number of cancer therapy techniques are based upon the observation that such incident radiation can dramatically degrade the reparability of DNA.The project will be carried out within the EU COST P9 network Radiation Damage in Biomolecular Systems appro ved
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Reducing climate based health risks in blue environments: Adapting to the climate change impacts on coastal pathogens' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

BlueAdapt brings together an interdisciplinary team of biologists, climate scientists, economists, epidemiologists and public health experts to investigate and quantify the future health risks associated with selected coastal pathogens. BlueAdapt will provide tools to assess the impacts of policy responses and communicate the results to a wide audience, including both policymakers and the public. A conceptual framework will be developed around existing models of One Health and Ecological Public Health, to help wider engagement with the complex nature of the issue. Horizons scanning and downscaled climate modelling will feed into lab based experiments and the development of simulations around how changes in climate variables, interacting with other environmental change, may influence the state of selected microbial pathogens of public health concern in coastal waters. Case studies will illustrate how One Health and Ecological Public Health concepts can be used to generate action and identify potential barriers to adaptation. Health impact assessment and cost-benefit analysis will inform appropriate action. BlueAdapt Innovation Slams and policy workshops will help deliver wider impact from the project including new-to-firm and new-to-market products and services.


**Keywords:** Climate change adaptation, cost-benefit analysis, decision support tools
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'New Paradigms for MEMS & NEMS Integration' to be submitted under Seventh Framework.

assistant: **Abstract**

Micro- and nanoelectromechanical system (MEMS and NEMS) components are vital for many industrial and consumer products such as airbag systems in cars and motion controls in mobile phones, and many of these MEMS and NEMS enabled applications have a large impact on European industry and society. However, the potential of MEMS and NEMS is being critically hampered by their dependence on integrated circuit (IC) manufacturing technologies. Most micro- and nano-manufacturing methods have been developed by the IC industry and are characterized by highly standardized manufacturing processes that are adapted for extremely large production volumes of more than 10.000 wafers per month. In contrast, the vast majority of MEMS and NEMS applications only demands production volumes of less than 100 wafers per month in combination with different non-standardized manufacturing and integration processes for each product. If a much wider variety of diverse and even low-volume MEMS and NEMS products shall be exploited, the semiconductor manufacturing paradigm has to be broken. In this project, we therefore will focus on frontier research on new paradigms for flexible and cost-efficient manufacturing and integration of MEMS and NEMS within three related research areas:(1)Wafer-Level Heterogeneous Integration for MEMS and NEMS, where we explore new and improved wafer-level heterogeneous integration technologies for MEMS and NEMS devices;(2) Integration of Materials into MEMS Using High-Speed Wire Bonding Tools, where we explore new ways of integrating various types of wire materials into MEMS devices;(3) Free-Form 3D Printing of Mono-Crystalline Silicon Micro- and Nanostructures, where we explore entirely novel ways of implementing mono-crystalline silicon MEMS and NEMS structures that can be
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'The modulation of vestibular reflexes during self-generated head-neck movements'.

assistant: **Concept**

Stable head posture is something most people take for granted, and is essential to perform daily activities such as balancing, navigating and moving. Neck muscles generate head motion to establish a stable reference frame for the visual and vestibular (i.e. balance organ) systems, allowing the rest of our body to engage in other motor behaviours. The vestibular system provides information regarding head motion in space, and is particularly important for neck muscle control. However, for people suffering from vestibular and neck movement disorders, even the smallest head movement, whether self-generated or imposed, can induce episodes of dizziness, imbalance and fatigue. This proposal investigates how vestibular information is modulated by the nervous system to facilitate head movements, knowledge which is crucial to understand vestibular and neck movement disorders, and eventually develop therapeutic protocols.Head motion will be manipulated using novel robotic devices to study how vestibular reflexes are modulated in healthy volunteers during externally imposed and self-generated movements. A unique motion coupled electrical vestibular stimulation will provide an artificial sensation of head movement that mimics normal or conflicting relationships with the intended motion. Vestibular reflexes will be quantified using stochastic stimulation of the vestibular organ together with system identification to estimate the sensory modulation process that occurs during head movements. This project takes a multidisciplinary approach, using engineering techniques to address physiological questions, generating knowledge that is applicable to the medical field. The fundamental insight into vestibular control of neck muscles will help understand how humans achieve skilled motor perfo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'The behaviour, fate and ecotoxicological effects of silver nanoparticles in estuarine and coastal waters'.

assistant: **Innovation**

The overall aim of this project is to establish the behaviour, fate and ecotoxicological effects of silver nanoparticles (AgNPs) in estuarine and coastal waters. Silver is a toxic element and increasingly used in NPs added to consumer products. This is resulting in AgNP release to marine waters. There is a lack of knowledge on AgNPs in marine systems, hampering development of legislation. The project has the following specific objectives:1.Manufacture AgNPs with different core sizes and coatings and establish their dissolution, surface properties and behaviour under different environmental conditions: Ag salts will be used to manufacture AgNPs and stable isotope 109AgNPs by chemical reduction using selected chemical agents2.Determine speciation of AgNPs in seawaters: Experiments will be conducted by spiking solutions with manufactured AgNPs of different chemical characteristics to study Ag ion release, kinetics of AgNP dissolution, solubility, shape and size changes of AgNPs. Furthermore, we will determine the concentration of AgNPs present in estuarine and coastal waters3.Study the toxic effects of AgNPs on marine organisms: We will undertake toxicological studies using phytoplankton and oyster embryo larvae. Experiments will be carried out by varying the AgNPs dose, exposure time and toxicological media.4.Establish a model of behaviour and fate of AgNPs in marine environments: The obtained data will be used for the development of mathematical models aimed to model the residence times, dynamic concentration profiles and aggregate size distributions of AgNPs in seawatersThe obtained results will address vital questions: Are AgNPs already present in EU seawaters? Can AgNPs be bioavailable in marine ecosystems? What is their speciation and toxicity in marine waters? Can a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Application of crop genetics to improve Calcium content in millets and other crops for promoting health benefits in the prevention and treatment of osteoporosis' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

With osteoporosis becoming an increasing threat to human health, this project is directed towards finding an inexpensive solution to this problem using crop genetics. Biofortification of human diet with food that are naturally rich in Calcium (Ca) is proposed. Among all cultivated cereals, finger millet (Eleusine coracana), an annual small millet of Africa and Asia, has been found to have the highest concentration of Ca (350mg/100g) in its grains. This proposal aims to investigate the genetic variations of Ca accumulation in finger millet germplasm using chemical phenotyping and genomics, and to use this knowledge in further improving the concentration of this micronutrient in finger millet and other staple crops. Specific objectives of the study are: (1) to explore the extent of genetic diversity for Ca content present in world collection of finger millet germplasms; (2) to identify genomic regions associated with Ca accumulation in finger millet grains using next generation sequencing, chemical phenotyping and GWAS analysis; (3) to identify and validate candidate genes underlying genomic regions found to be associated with Ca accumulation in finger millet; and (4) use comparative genomics to identify similar genes and processes in staple cereals like wheat, rice, barley or oats grown in Europe. The project will identify genes involved in Ca accumulation in crops and the prospects of their breeding into new varieties through plant breeding. Such crop varieties will benefit the smallholder farmers who will grow them (by adding value to their food products) and also provide valuable, superior raw material to industries for developing functional food rich in Calcium. Availabilities of such food and food products will increase Ca consumption and reduce the health and econo