RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Convergence Science Network of Biomimetics and NeuroTechnology' (CSNII), addressing dissemination and exploitation.

assistant: **Impact**

Despite tremendous progress in neuroscience, ICT and related fields we are still unable to build perceptive, emotive and cognitive systems that are comparable with even simple insect brains with respect to function, energy sufficiency or computational power. One promising approach to answer this challenge is to translate principles underlying the abilities of natural systems into new technologies. Such an advance would entail major societal and economical impacts, particularly in the areas of information and communication technologies, robotics, brain-machine interfacing, quality of life and health and nanotechnology applied to life sciences. In parallel this paradigm would boost our fundamental understanding of mind and brain: ourselves. Currently the fields of research in Neuro- and Bio-inspired Systems (NBIS) on which these developments depend are critically fragmented, lacking common objectives, methods, critical mass and penetration of the academic curricula with associated obstacles for growth and consolidation. The Coordination Action Convergent Science Network for Biomimetics and Neurotechnology (CSNII) will directly address these challenges. CSNII will advance the definition, visibility, federation and consolidation of research in the Future and Emerging Technology area of NBIS with specific emphasis on Biomimetics and Neurotechnology. CSNII will achieve these objectives by advancing and developing strategic roadmaps, supporting workshops, the annual conference Living Machines" and realizing global cooperation and alliances in particular through collaborations with similar and well established activities in the USA and Japan. At the end of this 3 year project we expect a measurable impact on the level of collaboration and the quality of research in Biomimetics
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'European Plant Phenotyping Network'.

assistant: **Innovation**

The ability to quantitatively analyze plant phenotypic traits (from single cells to plant and stand level) and their dynamic responses to the environment is an essential requirement for genetic and physiological research, and the cornerstone for enabling applications of scientific findings to bioeconomy. Whereas molecular profiling technologies allow today the generation of a large amount of data with decreasing costs largely due to automation and robotics, the understanding of the link between genotype and phenotype has progressed more slowly. Insufficient technical and conceptual capacity of the plant scientific community to probe existing genetic resources and unravel environmental effects limits faster progress in this field. The development of robust and standardized phenotyping applications depends on the availability of specialised infrastructure, technologies and protocols. Europe has become a key driver in defining innovative solutions in academic and industrial settings. However, the existing initiatives at the local or member-state level represent a fragmented research landscape with similar goals. The aim of this project is to create synergies between the leading plant phenotyping institutions in Europe as a nucleus for the development of a strong European Plant Phenotyping Network (EPPN). The project fosters the development of an effective European infrastructure including human resources, expertise and communication needed to support transnational access to user communities. Joint research activities will adapt and develop novel sensors and methods for application in plant phenotyping. Innovative phenotyping concepts integrating mechanistic, medium- and high throughput as well as field phenotyping will be developed and made available to the community.  Thi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'APCOCOS: Appearance Prediction of Colour Coatings based on under-surface Scattering and optical measurements of bi-directional reflection distribution function' to be submitted under Sixth Framework.

assistant: **Abstract**

The main objective of the project is to render paints with the focus on high quality output so that the final rendering will highly correspond to the human perception of the real paints. The problem of appearance prediction of paint from direct measurements of Bi-directional Reflection Distribution Function (BRDF) is solved here.We will focus mostly on modeling metallic and pearlescent paints. Rendering of coloured, metallic and pearlescent paints will be performed from BRDF data or eventually from Bi-directional Texture Function (BTF) data. We will consider both possibilities and choose the one, after considering benefits of each representation and additional statistical information about structure of metallic and pearlescent layer.The goal of rendering is not to perform visualization in real time with large number of frames per second; how ever-endering software will try to take advantage of programmability, high performance and parallelism of modern graphics cards in processing of data to achieve interactive or eventually nearly interactive results.We will propose a solution consisting of data acquisition from paint samples; new mathematical model based on multiple pigment layers; and new methods for storage and fast calculations on modern graphics processors (GP U).We will study the undiscovered optical processes within the paints; we will formulate the relation between paint composition and final appearance, based on which the paint composition (pigments) will be determined.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Uncovering Protein Mechanics in Physiology and Disease' (ProtMechanics-Live).

assistant: **Innovation**

Protein mechanics is a key contributor to the form and function of biological systems by mechanisms that are just starting to be unraveled. An ensuing hypothesis is that alteration of protein mechanics can trigger disease, particularly in mechanical conditions such as cardiomyopathies in which primordial underlying molecular mechanisms remain elusive. Although tempting, this possibility has not been tested due to the absence of methods that can modulate the mechanics of proteins in vivo. My proposal aims to overcome technical barriers to scientific progress by establishing manipulation of protein mechanics in living cells and animals as a new research field. In aim 1, we will address current technological limitations through the generation of genetic, protein-engineering-based mechanical loss- and gain-of-function models to interfere acutely and reversibly with protein mechanics in living systems (mLOF and mGOF, respectively). We will apply these first-of-their-kind tools to the giant protein titin, a major contributor to the force-generating and sensing properties of cardiomyocytes with strong links with heart disease, and a workhorse protein that has been instrumental in the past to understand the biophysics of polypeptides under force. In aim 2, we will exploit cellular mLOF and mGOF to define how perturbations of titin mechanics result in altered cardiomyocyte force generation, mechanosensing, mechanotransduction, differentiation and proliferation. Leveraging on our cell studies, in aim 3 we will use murine mLOF and mGOF to shed light into the contribution of titin mechanics to the onset and progression of genetic and acquired cardiomyopathy. ProtMechanics-Live builds on our unique expertise in protein mechanics and engineering, biophysics, biochemistry and cardiova
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Ecology and evolution of ant communities in tropical ecosystems' (2007-2013) under Seventh Framework.

assistant: **Objectives**

This project proposes a comprehensive study of the ecology and evolution of tropical ants at the community, species and population levels. It will be based on unique data set of 11000 samples collected from 17 sites in New Guinea and northern Australia. This study will be the first to examine species distributional data combined with their population and species phylogenetic relationships across a large regional spatial scale. The multidisciplinary methodology will permit the novel analysis of the environmental, evolutionary and geological factors influencing the diversity and distribution of ants in lowland tropical ecosystems. This project will use state of the art techniques in phylogeography and community ecology to address important questions of wide relevance about the evolution of insect communities, and will provide important knowledge relevant to conservation of tropical rainforest and savanna ecosystems. The proposed research will be combined with high quality training in phylogenetic and population genetic methodology, provided by world leading experts in this area.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Smart Autonomous Multi Modal Sensors for Vital Signs Monitoring' in the context of a Horizon 2020 call.

assistant: **Objectives**

Cardiovascular diseases (CVD) remain the leading cause of mortality and a major cause of morbidity in Europe. Every year there are more than 6 million new cases of CVD in the EU and more than 11 million in Europe as a whole. With almost 49 million people living with the disease in the EU, the cost to the EU economies is €210 billion a year. There is a growing demand for a reliable cardiac monitoring system to catch the intermittent abnormalities and detect critical cardiac behaviours which, in extreme cases, can lead to sudden death. The objective of the Smart Autonomous Multi Modal Sensors for Vital Signs Monitoring (SmartVista) project is to develop and demonstrate a next generation, cost-effective, smart multimodal sensing platform to reduce incidences of sudden death caused by CVD. The key innovation in SmartVista is to integrate 1D/2D nanomaterials based sensors to monitor the heart, thermoelectric energy harvesters to extract energy from the body to power the system and printable battery systems to store this energy. Together these will result in a self-powered device that will autonomously monitor the electrocardiograph, respiratory flow, oxygen flow and temperature of the patient. This information will then be transmitted wirelessly for online health processing. This real-time self-powered monitoring of a patient’s health in this manner is not currently available so the technology that will be developed in SmartVista will position us at the forefront of digital health and wearable biosensor technology for wireless monitoring in hospitals and of remote patients, both of which are necessary in this era of an aging population. The SmartVista platform enables wireless, real-time, continuous patient monitoring and delivers a seamless feed of patient data and will con
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Blood Biomarker Array Technology' (LIBERATE).

assistant: **Innovation**

Treatment of patients occurs principally in two places: the primary setting with a physician and the secondary setting in hospital. The remote setting of a care home, the patient’s home or remote isolated communities is by comparison under exploited. Projection of real diagnostic power derived from blood biomarker biochemistry into these remote communities is possible using a small volume multi-biomarker array technology that can deliver all of the tests of a clinical biochemistry laboratory in a small-form disposable format performed by the patient. A telemedicine solution brings the data back to the clinician for expert analysis and diagnosis. Our blood biomarker array technology will provide healthcare for an aging population keeping them in their homes for longer and provide timely personalised interventions for the management of chronic conditions. “Knowing your numbers” means a patient will understand their own acute phase response to infection or inflammation not requiring the comparison against normal ranges for diagnosis. Preliminary studies indicate 6 assays will be important: CRP and White Blood Cells, markers of the acute phase response; D-dimer the a blood clot biomarker; Troponin I/T/C the heart attack biomarker; and C3 and C4 Complement proteins for differential diagnosis of bacterial infection. The project will look at these and other assays to form a General Diagnostic Array for management of healthcare in remote communities, in health disease and during recovery.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Catalytic Foldamers: Engineering a Second CoordinationSphere Around a Hydrogenase Mimic' under Seventh Framework.

assistant: **Concept**

The protein environment that surrounds metalloenzyme active sites imparts a wide range of effects that facilitate catalysis. Supramolecular supports for homogenous catalysis may model a number of these effects. However, the use of dendrimers or polymers to provide directed second coordination sphere effects is limited by their unpredictable/unstable structures. Foldamers, based on aromatic amide units, have structures that are both highly stable and predictable in a wide range of solvents. These qualities and the modular approach to their synthesis allows for engineering of cavities of defined size with an organized array of functional groups. This project plans to explore the application of foldamers as supramolecular supports for small molecule mimics of metalloenzyme active sites, specifically [FeFe]-hydrogenase, and in doing so develop a new generation of hydrogenase models with a well defined and tunable second coordination sphere. The research involves the in silico design, and chemical synthesis of foldamers that incorporate small molecule models of [FeFe]-hydrogenase. Through electrochemical and variable temperature NMR studies, the effect of the support on the fluxional and electrocatalytic properties of the model complex will be studied. The applicant has experience in the synthesis and characterization of biomimetics of [FeFe]-hydrogenase and the use of supramolecular supports (cyclodextrins) for their encapsulation. Through joining a host lab in France that specializes in the synthesis and structural characterization of aromatic amide foldamers, this expertise in bioinspired catalysts will be transferred via the proposed cooperative work. Additionally the applicant would act as an envoy between the host lab and a group in Germany, with whom the host lab has
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'COmputing with Mesoscopic Photonic and Atomic States' (COMPAS) targeting Seventh Framework.

assistant: **Abstract**

In the recent years, continuous variables (CV) have emerged as a viable and very promising alternative to the traditional quantum bit-based approaches to quantum information processing. Encoding CV information onto mesoscopic carriers such as the quadratures of light modes or the collective spin of atoms offers several distinct advantages, such as the deterministic generation and manipulation of entangled states of light and atomic ensembles, or the interface between light and atoms allowing the implementation of a quantum memory. This toolbox of available operations has recently been significantly extended by conditional photon subtraction, which allows the generation of highly nonclassical states with negative Wigner functions. This opens access to the realm of non-Gaussian operations, which are essential to several critical applications such as CV entanglement distillation or CV quantum computing.<br/>By building on these recent spectacular achievements, the present project aims at carrying out exploratory research on mesoscopic CV quantum information systems, with the ambitious ultimate objective of designing the first small-scale quantum processor using this CV toolbox. In an interplay between theory and experimental research, the consortium will investigate the hitherto unexplored potential of CV quantum computing and will address all necessary steps on the way to mesoscopic CV processors. This includes the engineering of non-Gaussian operations on photonic and atomic states exploiting the measurement-induced or actual nonlinearities between light and atoms, CV quantum computing with cat states or cluster states, CV entanglement distillation, error correction, and quantum repeaters. It is anticipated that the present project will have a strong impact on the future
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'The Theatrical Landscape of Bohemia and Moravia as a Space of Negotiating Cultural Identities'.

assistant: **Innovation**

TheatLandIdent aims at analysing the negotiation of cultural identities in a multiethnic and multilingual sphere. It identifies theatre as a major scene of this negotiation in relation to local, regional and national frames of reference, thus questioning the colonial logic of centre and periphery.In the Austro-Hungarian Monarchy during the 19th Century, a German-speaking municipal theatre became a city’s most important institution for proving its contribution to high culture, its modernity and its inclusion in the field of German culture. My main thesis is that the process of modernisation was not a simple cultural transfer from the centre to the so-called periphery. Instead, the Monarchy’s multiethnic regions had their own logic of circulation, thereby maintaining a reciprocally interdependent relationship with the centre. In this relationship, the region of Bohemia and Moravia was ‘inventing’ itself as a theatrical landscape in which the theatres functioned as stepping stones for artists who later became famous in Vienna or Berlin.My project takes a close look at the ways in which the cities and theatres construed this theatrical landscape. It analyses both the cultural and social practices performed in and between the theatres and the narratives of this landscape. The temporal outline stretches from the Austro-Prussian war in 1866 to the outbreak of World War I in 1914. For the Habsburg Monarchy, these two dates mark decisive points for the understanding of German identity which became a concept under negotiation. Nationalism’s pursuit of hegemony downgraded the productive liminal sphere of the multiethnic periphery into a border or frontier region. The historical example of this theatrical landscape helps to better understand how identities are formed through cultur
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Bioprocesses for metabolite production from marine invertebrate cell lines' (BLUES), addressing dissemination and exploitation.

assistant: **Impact**

The objective of BLUES is to expand the potential to produce valuable and unique bioactive compounds from marine invertebrates by developing novel cultivation systems of cell lines from 4 phyla of marine invertebrates (Porifera, Cnidaria, Echinodermata, Chordata) and optimizing production yield as an alternative to wild harvesting. For many years, research has been done to derive continuous cell lines from invertebrates. Only recently, BLUES partners reached a breakthrough and created the first continuous marine sponge cell line. Results demonstrated that sponge cells of several species can divide extremely rapidly.The ambition is to design the pathway towards industrial bioprocesses using marine invertebrate cell lines of different phyla as a chassis towards the production of unique high-value marine bio-based compounds, an environmentally sustainable alternative to wild harvesting. The novel bioprocesses that will be developed are not only an alternative for wild harvesting, solving the stock production bottleneck for increased availability of the bioactive compounds, but also for a higher level of sustainable alternative, contributing to the development of circular processing and circular economy.The technology that will be developed in BLUES will make it possible that valuable marine-natural products are produced in bioprocesses and with that contribute to the Blue Bioeconomy.


**Keywords:** Sponges, Ascidians, Corals, Sea Cucumber, Green solvents, Cell culture