RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Bringing innovation forward to fuel powered engines by disrupting Total Combustion Technology to drastically reduce the emissions of motorcycles and Small Off-Road Engines (SORE)' (SORE), addressing dissemination and exploitation.

assistant: **Impact**

Over 70 million motorcycles and 100 million Small Off-Road engines (SORE) are produced annually worldwide, and market prospects for both markets are splendid: Global demand for motorcycles is projected to climb 3.8% per year through 2020 to 113 million units, valued at $120 billion and the SORE market has a value of $17.7 billion with constant growth. However, pollutant emissions from combustion engines in these devices significantly contribute to air pollution. Therefore, emissions regulations are being released (such as Euro 5 standards for motorcycles, and EU’s Stage V Regulation 2016/1628 for SORE) which can hinder the growth of these markets, as current carburettors (responsible for engines’ emissions) cannot comply with these increasingly stricter regulations. At Fjölblendir ehf we have developed a disruptive fuel injection system, TCT, which will not only allow small motorcycle or off-road engines (250cc) to abide to the stringent emissions regulations, but also perform extraordinarily, guaranteeing a complete combustion as well as increasing fuel efficiency (up to 25% of fuel reduction), torque (25% more) and power at a competitive price. We have already established an agreement with Tillotson (a carburettor manufacturer, OEM for small engines and expert in innovative fuel systems and high performance small engine operation with 73 dealers in 20 countries) to produce the mechanical versions of TCT, and at this point we are focused on developing the new electronic versions of TCT carburettors, which will enhance engines’ performance even more. The overall objective of this TCT project is to achieve the industrialisation of TCT electronic carburettors, and in this way contribute to reducing the environmental impact of both motorcycles and SORE.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Development of a parabolic Trough concentrator system for Molten Salt Application'.

assistant: **Concept**

Within the MSA-Trough project a fix-focus parabolic trough is developed by an international consortium of 7 partners. The novelty of the new collector is the complete independence (detachment) between the concentrator and the fixed absorber tube, so that the absorber tube string is not moved by the concentrator and can be designed in a continuous line up to a length of more than 0,8km. Due to the new design not only the collector connection piping becomes obsolete but also all flexible connections in the solar field are omitted, leading to a significant reduction in investment costs as well as in pressure drop and heat losses. Because of its horizontal “storm-position” wind loads are reduced by 75%, thus steel structure, pylons and foundations can be designed very light and cost-saving. In addition, biodegradable and very stable thin-glass sandwich mirrors will be developed, which increase the optical efficiency by 2% due to better reflectivity. A further important project highlight is the development of an automatic mirror washing device, which will recycle about 90% of washing water and increase the solar field performance by 4% because of daily washing. The new MSA-Trough design will be especially suitable for dispatchable power generation at very high temperature (555°C) using directly molten salt as heat transfer fluid and storage medium, thus reaching a very high cycle efficiency and an excellent volumetric storage capacity. A 350m-collector (aperture 6,7m) will be erected and tested with molten salt at the EMSP. Optical, mechanical and thermal tests will be carried out in order to verify the collector quality and efficiency. In order to eliminate heat losses during nights the “overnight drainage strategy” will be tested and optimized. Compared to current paraboli
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Fulfilling Paul Ehrlich’s Dream: therapeutics with activity on demand' (ZAUBERKUGEL), addressing dissemination and exploitation.

assistant: **Impact**

Paul Ehrlich was the first scientist to postulate that if a compound could be made that selectively targeted disease-causing cells, then this agent could be used for the delivery of a toxin, which would enable a pharmacotherapy of unprecedented potency and selectivity. With this procedure, a ""magic bullet"" (Zauberkugel, his term for an ideal therapeutic agent) would be created, that killed diseased cells while sparing normal tissues.The concept of a ""magic bullet"" was to some extent realized by the invention of monoclonal antibodies, as these molecules provide a very specific binding affinity to their cognate target. However, monoclonal antibodies used as single agents are typically not able to induce cures for cancer or chronic inflammatory diseases. More recently, intense academic and industrial research activities have aimed at “arming” monoclonal antibodies with drugs or cytokines, in order to preferentially deliver these therapeutic payloads to the site of disease. Unfortunately, in most cases, ""armed"" antibody products still cause unacceptable toxicities, which prevent escalation to potentially curative dose regimens.In this Project, I outline a therapeutic strategy, which relies on the use of extremely specific tumor targeting agents, for the selective delivery of payloads, which can be conditionally activated at the site of disease. Methodologies for the conditional generation of active payloads include the stepwise non-covalent assembly of cytokines and the controlled release of cytotoxic drugs at suitable time points after injection, when the concentration of therapeutic agent in normal organs is acceptably low. Response to therapy will be profiled using innovative proteomic methodologies, based on HLA-peptidome analysis.Pharmaceutical agents with “activ
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Methodology for efficient segmenting innovating SMEs based on lifecycles, represented sectors and regional characteristics', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

SMEthod is a research project aimed at delivering an improved methodology of identifying SME’s pathways to innovation and of segmenting innovating SMEs in order to determine optimal targeting and timing of support measures allocated by innovation agencies and other institutions. A complementary goal is to create a decision support tool (DST) ) which will be devolved in cooperation with the relevant stakeholders who implement innovation policies and by compiling the complex SME innovativeness determinants will offer them a flexible evaluation tool. Broad dissemination activities are also planned to reach innovation stakeholders, innovation and regional development agencies, ministries, etc.The SMEthod methodology will consider important factors that are likely to influence companies and the societal impact they create. In particular, enterprise lifecycle, industrial sectors, regional characteristics, and innovation cycles will be scrutinized. New segmenting criteria for innovation support policies will be prepared and specific variables will be determined and weighted in order to assure usability of the methodology. The holistic character of the project will be assured by proposing a more efficient allocation of appropriate pro-innovation measures.Most common and relevant methodologies of segmenting SMEs for the purpose of innovation support will be evaluated as well. Furthermore, efficiency of selected methods and techniques will be assessed. Conclusions from the research will be merged to deliver a final product of the project – a holistic methodology and the DST based on it.The project’s impact will be a better understanding of innovation dynamics and potentials in SMEs and of their efficient segmentation. New knowledge will be created on the effectiveness of innovati
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Microfoundations of Collective Defence' (MICROCODE) under Horizon Europe.

assistant: **Objectives**

Does the success of military alliances ultimately hang on the whims of public opinion? The historical record shows that allied states often do not honour their collective defence commitments, but existing scholarship has not yet explained the role of public views in these high-stakes decisions. The MICROCODE project aims to initiate a new research agenda on the microfoundations of collective defence that puts public opinion in allied countries at the centre of inquiry. Building on cutting-edge approaches in experimental political science, international relations, and political psychology, I aim to conduct an extensive, cross-national investigation in the key NATO member states, with the views of individuals as the principal unit of analysis. I introduce a complex theoretical model to explain (1) how individuals form attitudes towards allied assistance in different collective defence scenarios; (2) how these individual attitudes aggregate to form public opinion shaped by societal cues; and (3) how, in turn, public opinion shapes the views of decision-makers in allied states. My main set of hypotheses concerns the critical impact of the strategic context on the formation of public opinion and its relevance for policy-making: I propose that whereas conventional scenarios of direct armed aggression leave a limited role for public opinion, the more ambiguous “grey zone” conflicts potentially open a wide “contestation space” where public views become more polarised, elastic, and simultaneously more relevant for decision-makers. As a methodological innovation, I will use novel immersive mixed-media experiments to create an interactive, engaging, and realistic experience for the participants and examine how their attitudes towards defending allies change under different conditi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Characterization of polynomial filters for image enhancement and the extraction of invariant image features' demonstrating excellence, impact and implementation quality for a Fourth Framework call.

assistant: **Abstract**

Research objectives and content The objective of the proposed research project is the inclusion of methods for image enhancement using polynomial filters in an already developed nonlinear adaptive system for invariant pattern recognition. The link between low and high level image processing consists in the similar structure of the polynomial filter kernels used for image enhancement and for the invariant feature extraction method. To achieve an effective combination the focus of the project will be on the derivation of a systematic characterization of polynomial filter kernels suitable for certain tasks by including a priori knowledge about the patterns in a given application. Together with the adaptivity of the pattern recognition system the proper choice of the filter kernels will lead to a substantial increase in robustness and separation ability, and a reduction of computational costs compared to general purpose image processing systems. Training content (objective, benefit and expected impact) The design of the polynomial filters for image enhancement is based on Volterra theory whereas the filters used for the invariant feature extraction method are based on invariant theory. From a combination of these two approaches synergy effects are expected for the construction of a fast adaptive invariant image processing system as well as for the fields of image enhancement and invariant pattern recognitio individually.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Evaluation of Plant Signaling Networks in Natural Environments' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

A critical characteristic of plant development is the strong influence of environmental factors as modulators of developmental programs. Among those factors, light, temperature and nutrient availability dominate developmental decisions, and can dramatically alter plant shape, biomass production and fruit set –all of them important agronomic traits. Research during the past thirty years has defined different molecular mechanisms by which plants perceive environmental signals and transduce this information into changes in gene expression and other cellular processes, ultimately triggering the appropriate adaptive responses. However, current knowledge has at least two important weaknesses: (i) it is based on mostly on the analysis under conditions where only one environmental factor is changed, while natural environments are more complex; and (ii) most studies have been performed at the seedling stage, while the influence of the environment becomes even more relevant at later stages from an agronomical perspective. This project addresses the evaluation plant performance under complex combinations of light, temperature and nutrient conditions, using the previous knowledge generated by the participants and other laboratories, and analyzing three key stages of a plant’s life: seedling establishment, vegetative growth (biomass production), and reproductive development (flowering and fruit set). The international consortium is formed by researchers from five countries, with strong complementary technical and scientific expertises spanning light and temperature signaling, hormone action, natural genetic variation, large-scale phenotyping of adult plants, nutrient assimilation and systems biology integration.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'SUstainable federatioN of Research Infrastructures for Scaling-up Experimentation in 6G' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

6G is expected to emerge as key enabler for the intelligent digital society of 2030 and beyond, providing superior performance via groundbreaking access technologies, such as joint communication and sensing, cell-free, Radio Intelligent Surfaces, and ubiquitous wireless intelligence . Most importantly, 6G is expected to trigger a total rethink of network architecture design, which builds on the key idea of new stakeholders entering into the value chain of future networks. The SUNRISE-6G approach is inspired by the “network of networks” concept of 6G Networks, aiming to integrate all private and public infrastructures under a massively scalable internet-like architecture. SUNRISE-6G similarly aspires to create a federation of 6G test infrastructures in a pan-european facility that will support converged Testing as a Service (TaaS) workflows and tools, a unified catalogue of 6G enablers publicly accessible by experimenters, and cross-domain vertical application onboarding. Experimentation and vertical application onboarding are offered via a Tenant Web Portal, that acts as a single-entry point to the facility, serving end users (e.g., experimenters) and tenants (e.g., vertical developers, infrastructure owners, 6G component manufactures). The project execution is based on 4 pillars, delivering: (a) the Implementation of new 6G enablers, complementary to existing ones being developed in SNS Phase 1 projects, (b) A truly scalable and 3GPP compliant Federation solution that provides access to heterogeneous resources and devices from all Europe, (c) A Federated AI plane aligned with AIaaS and MLOPS paradigms, which promotes a collaborative approach to AI research which benefits immensely from scaling-up datasets and models and (d) a commonly adopted Experimentation Plane, whi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Integrated health technology assessment for evaluating complex technologies' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

The rise of complex, chronic diseases in an ageing European population led to the development of increasingly complex technologies. Current HTA is not well equipped to assess complex technologies due to a lack of attention to the diversity in patient characteristics and patient preferences, the limited consideration of context and implementation issues, and missing strategies to integrate all these aspects into a comprehensive assessment.We shall develop concepts and methods for HTA to enable a patient-centered, integrated assessment of the effectiveness, and the economic, social, cultural and ethical issues of complex technologies that takes context and implementation into account. We shall use palliative care for our case study as it is of extremely high relevance and it is an excellent example for a highly complex technology.More specifically, we shall adapt and develop methods and concepts-to assess the effectiveness and economic, social, cultural, and ethical issues of complex technologies,-to elicit patient preferences and patient-specific moderators of treatment-to include context, setting, and implementation-and, finally, to integrate these issues into a patient-centered, comprehensive assessment of complex technologies.Concepts and methods will be tested through assessing the complex technology “Specialist palliative care”. Revised guidance will be issued for comment to all relevant stakeholders.All partners of the consortium have an outstanding track record in the development of HTA methodology and are actively involved in major international initiatives in the field. The project will complement the work of similar initiatives and projects on HTA development, especially EUNetHTA/EUNetHTA JA and inform HTA agencies in all European countries. By focusing on an i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'Mitochondrial deficiency and cardiomyopathy. Role of Reactive Oxygen Species'.

assistant: **Objectives**

Mitochondrial diseases are now considered to be among the most common forms of genetic disorders, with a minimum prevalence of 1 in 5000 individuals. They can be caused by mutations in either the nuclear or the mitochondrial DNA (mtDNA). One of the most well characterized clinical presentations is neuromuscular dysfunction, followed by cardiomyopathy, generally in the form of hypertrophic cardiomyopathy. Nowadays there are several clinical treatments approved for mitochondrial diseases. However true treatment is, with some exception, unavailable due to the complexity of the disease and the side effects observed.Several mutations involving mt-tRNA genes (mainly Leu1, Lys and Ile), mt-encoded protein and nuclear encoded protein genes have been associated with cardiomyopathy. Some of these mutations have been deeply studied in a cybrid cell culture model at the biochemistry level. However, very little is known about the signalling pathways that could lead to the development of cardiomyopathy. Mitochondrial physiology and biogenesis are deeply involved in the initiation and progression of the disease, through reactive oxygen species (ROS) production, energy deficiency and decrease in mitochondrial respirasome formation, as initial steps in the formation of the plaques. Recently, it as been demonstrated the role of some mitochondrial biogenesis-related genes, such as PGC1a, in mitochondrial fusion, pointing to the importance of the balance between mitochondrial fusion-fission in the progression of the disease. Interestingly, some of the mutations described in cardiomyopathy are very ROSgenic, strongly pointing to ROS and mitochondrial deficiency as an initial step in the onset of the cardiomyopathy.The aim of this project is to better understand the involvement of mitochondr