RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'RESERVOIR QUALITY MAPPING THROUGH NUMERICAL PREDICTION OF MINERAL DIAGENESIS'.

assistant: **Concept**

The project aims at predicting porosity evolution in the deep-seated North Sea reservoir units of the Brent Group sandstones, in the HILD Field through application of new numerical tools designed to compute the porosity volume changes produced by mineral diagenesis and their impact on reservoir quality.The purpose of the project is to demonstrate that the integrated use of advanced software can be flexible, efficient, and reliable enough to be routinely" applicable by an oil company at the exploration, appraisal, and development stages.It will demonstrate that the correct knowledge of diagenetic effects on reservoir leads to an accurate determination of the spatial distribution of reservoir properties.In production, this new technology will increase the accuracy of the reservoir model and will have a significant impact upon the economics of marginal hydrocarbon accumulations.Improvements in oil recovery understanding could be expected.Phase 1 : finishedPhase 2 : in progress, but slightly delayed.Phase 3 : Even though sampling and sedimentological studies presented no problems, the project is running late with respect to the proposed schedule. This is due to long turn-around times at each steps of the data acquisition process. According to this, the diagenetic sequence, discussed early 1998, was only confirmed in June. Even though code tests were possible, using an estimated diagenetic sequence, code processing faces several problems of adjustments (realistic mineral data set, unexpected code problems). However, the work is new well advanced. The six-month contract extension accepted by EC will allow to meet the final objective in due time (June 1999) whilst the geochemical modelling is progressing according to the new schedule.The Brent sandstone porosity evolution with
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Market-Based Initiatives as Solutions to Techno-Scientific Problems' in the context of a Seventh Framework call.

assistant: **Objectives**

MISTS engages with market based initiatives employed as potential solutions to techno-scientific problems. MISTS will draw together two strands of STS research: the turn to research on markets and STS literature on science problems (and solutions). These two areas will be drawn on in exploring four sub-projects which feature market based initiatives as solutions to problems: an attempt to build a market for privacy; an initiative to incentivise vaccine research; a scheme through which trading of evidence in electronic waste could take place; and a national system to render STS research competitive.Objectives:To enhance our understanding of the ways in which market based initiatives are increasingly being harnessed to address techno-scientific problemsTo understand the genesis, development, experience and consequence of utilising markets as solutions to problemsTo analyse in-depth the recursive nature of problem-solution relationshipsTo draw together hitherto often separate strands of STS researchTo develop and consolidate a research programme focused on techno-scientific markets, problems and solutionsMarket based initiatives are pervasive as apparent solutions to techno-scientific problems. From the management of waste, to attempts to invigorate competition in (social) scientific research, markets are heralded as a means to redistribute economic and moral value, reorient priorities and stimulate action. However, market based initiatives are also frequently critiqued for their apparent failure, for shaping the actions of those subject to them and for a broad variety of other unexpected and unintended consequences. The four sub-projects, addressing key areas of contemporary concern – privacy, health, environment and the future of academia – will form a research programme
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'RObust simulation Systems exploiting AI based turbulence models and hight-fidelity algorithmS'.

assistant: **Concept**

To meet global EU objectives related to aeronautical industry competitiveness and climate-neutrality, highly advanced design technologies are needed to allow fast and reliable evaluations of innovative configurations. ROSAS  aims at exploiting Artificial Intelligence (AI)/Machine Learning (ML), coupled with recent advances in Computational Fluid Dynamics (CFD) technology and the underlying turbulence modelling to reduce expensive and time-consuming physical testing and drastically accelerate the whole design optimization process.Partners will build a methodology based on defining test cases, targeting the key flow problems encountered in industrial applications and reproducing them precisely in a controlled environment via Hi-Fi simulations or experiments. The results will be gathered in a database which will serve the development and testing of novel data-driven methodologies (AI-ML) and mesh generation algorithms. Improved turbulence models, including multi-fidelity surrogate models with advanced verification and validation process, will be created with modifications based on new theoretical considerations and AI-ML-based modifications, resulting in hybridization of specific turbulence models. In addition, Application Challenge test cases will be defined in relation to Clean Aviation applications to match closely industrial configurations of interest, to assess and demonstrate the new methodologies developed in the project.ROSAS brings together 14 partners from 8 EU countries and 1 from UK. The consortium comprises 4 leading research organizations, 5 leading university groups, a Super-Computing Centre, and 3 major aeronautical industries. All partners will bring their innovativeness, infrastructures, and long experience in design and aerodynamics modelling, ensuring i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Epigenetic Deregulation of Apoptotic Gene Expression in Hepatocellular Carcinoma (HCC)' (HCC) targeting Seventh Framework.

assistant: **Abstract**

Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide and thus constitutes a major health problem involving more than half a million new cases every year. During its promotion stage, HCC has been associated with defective apoptosis and increased cell proliferation. Only recently, gene expression has been shown to be regulated by epigenetics (reversible heritable changes in gene regulation that occur without a change in DNA sequence) involving changes in DNA methylation patterns as well as specific histone modifications. Throughout our proposal, we speculate that alterations in DNA methylation patterns trigger specific histone modifications resulting in apoptotic gene silencing during HCC. Thus, we propose to test the hypothesis that epigenetically-induced deregulation of the apoptotic pathway promotes transformation to malignancy. To conclude, although the deregulation of the apoptotic machinery in carcinogenesis is well established, there is a gap in our understanding as to how apoptotic genes are involved and how is their expression regulated in malignancy. Our proposal fills in the gaps in linking the epigenetically-induced alterations in apoptotic gene expression to the defective apoptotic phenotype characteristic of HCC. Furthermore, our proposal elucidates the molecular mechanisms by which specific histone modifications converse with the DNA methylation machinery in order to silence specific apoptotic genes. Finally, determining the molecular identity of these epigenetic modifications is of paramount importance because such information can be utilized in designing more efficient cancer therapeutic strategies based on the concept of selective apoptotic activation in malignant cells thus making such strategies more efficient and less cytotoxic.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Advanced catalyst electrodes from Ionic liquid modified PtNi nanowire arrays for PEFCs' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Recent developments in PEFC research have seen a significant enhancement of catalyst activities and a reduction of cost at a reduced loading of precious metals by employing novel Pt-based extended surface area nanostructures alloyed with transitional metals, but the low stability caused by the easy dissolution of transitional metals in acidic PEFC environment, and the large difficulty to be integrated into devices due to the unconventional morphology of extended surface area nanostructures as Pt/C nanoparticle catalysts limit them mainly to pure material research, resulting in an increasing gap with real high performance devices. IonPEFC will bring together the chemistry of nanostructure and ionic liquid (IL) synthesis with the engineering of fuel cells to develop PEFC electrodes with thin film catalyst nonstructures from PtNi nanowire arrays modified by protic ILs, targeting an improved understanding of structure-property relationships of electrodes to build high performance and robust PEFC devices. This will involve 4 research objectives:1. To develop electrodes with thin film catalyst nanostructures from PtNi nanowire arrays based on the in-situ growing approach and to study the effect of post acid washing and annealing on the surface properties of PtNi nanowires.2. To synthesize super hydrophobic, electrochemical and thermal stable ILs with high proton conductivity, oxygen solubility and diffusivity. The as-prepared ILs will be used to modify PtNi nanowire electrodes obtained to protect catalyst surface from Ni leaching in fuel cell operation. 3. To test in single cells the as-prepared and IL modified PtNi nanowire electrodes, and compare with conventional Pt/C electrodes.4. To evaluate the long-term durability of the electrodes under real life-context at different
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Improving health systems towards equality-based control of cervical cancer in latin america. comparing pap smear cytology, aided visual inspection, cervicography and human papillomavirus testing as optional screening tools in brazil and arg' demonstrating excellence, impact and implementation quality for a Fifth Framework call.

assistant: **Abstract**

The objective of the present proposal is to elaborate the research data needed to design a cost-effective strategy for cervical cancer screening in Brazil and Argentina, by using a combined cross-sectional (n=26.000) and cohort (n=1.250) study of women examined in four different clinics for the prevalence, pathogenesis and natural history of CIN and HPV (human papillomavirus) infections. The performance of the traditional diagnostic tools (cytology, colposcopy) is compared with the HPV detection methods (Hybrid Capture II and PCR) and suggested screening tools for low-resource-settings (aided visual inspection, cervicography and self-sampling for HPV) in detecting significant cervical pathology. Based on these data, health care systems in these two countries can be improved by designing the cost-effective strategy for cervical cancer control, with particular focus in increasing the coverage of the vulnerable groups.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'European Climate and Energy Modelling Forum'.

assistant: **Innovation**

The aim of ECEMF is to provide the knowledge to inform the development of future energy and climate policies at national and European levels. In support of this aim, ECEMF proposes a range of activities to achieve five objectives and meet the four challenges set out in the call text.ECEMF’s programme of events and novel IT-based communications channel will enable researchers to identify and co-develop the most pressing policy-relevant research questions with a range of stakeholders to meet ambitious European energy and climate policy goals, in particular the European Green Deal and the transformation to a climate neutral society.Answers will be provided by the first inclusive and open full-scale model comparison exercise on achieving climate neutrality in Europe, including from the outset over 20 models and 15 top research groups, to produce a coherent and relevant evidence-base for energy and climate policy impact assessment.ECEMF’s evidence-base will support the development of policy-relevant insights which will be communicated to and discussed with the key decision makers via a range of novel methods, including interactive embeddable visualisation blocks, policy briefs, workshops and high-profile events.This loop of knowledge co-production stands on two pillars.First, ECEMF will advance the state-of-the-art of energy and climate modelling by enabling sharing of: input data using open standards, methods for model comparison building on the vast experience of the consortium, scientific software tools such as the IIASA scenario explorer and hands-on training for researchers.Second, ECEMF will be established as a long-term, open and welcoming European focal-point for researchers and policy makers with unparalleled international connections to the EMF, JMIP, IAMC and IPCC
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Atomistic to Molecular to Bulk Turbulence' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

ATM2BT will combine pioneering methods to investigate the invariable different stages and bifurcating sequences of the onset of turbulent hydrodynamics at scales just above the Kolmogorov scale, applied to a variety of geometric configurations for a three-front approach in simulating, probing and understanding the structure of turbulence: turbulence, with its effects in our daily lives at the macro-cosmos captured from its fingerprints at the nano-scale. By bringing together the atomistic fluid and plastic flow at nano/micro-scale and their instabilities we will extend acquired knowledge through new innovative technologies to bulk fluid dynamics at the macro scale, in order to better understand fundamental aspects of turbulent flow and, through its plastics pathway, apply it to better engineering solutions. We are bringing together a diverse world leading multidisciplinary team comprising of Japanese, USA and EU (AST, Queen Mary College, Aristotelio) Institutions in order to create a comprehensive, accurate and reliable predictive modelling framework to probe the inner secrets of turbulence.  The different and diverse expertise available will not just enable, but actively encourage interaction and knowledge sharing to improve current understanding and enable new technology creation. The teams will address the challenges associated with the effect of the dominant nano/microstructure and its role in upscaling stochasticity to the macro scale, in order to create a fully deterministic, holistic, innovative multiscale framework, which will be tested and validated at a range of scales as part of the project delivery.  Our final goal will be to bring this framework of theoretical discoveries, represented in the form of a Unified nano-macro fluid flow accumulating state-of-the-
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Speckle Technology and Digital Biomarkers of Microvascular Function for Monitoring  Cardiovascular Diseases' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

Over 60 million people in the EU live with cardiovascular diseases (CVDs), at an annual economic cost of +210B€. Despite being largely preventable, CVDs cause more than 18.5 million deaths every year. To combat this, we develop new instruments for assessing adverse changes in microcirculatory status linked to hypertension, chronic kidney disease (CKD) and heart failure (HF), leading to earlier detection of CVDs. The instruments are developed and validated in clinical trials. We integrate two state-of-the-art technologies leading to a novel innovation, 3D speckle tissue monitoring. In addition, we demonstrate a direct use-case for unobtrusive monitoring in a smart-toilet application.  Global remote patient monitoring (RPM) systems market is expected to surpass 5 B$ by 2030 with CAGR of 20%. The demand for the RPM systems is rapidly growing among the old age population. Monitoring innovations targeting this group can reduce hospitalization and costly chronic conditions. Furthermore, the technology is closely linked to wearable remote monitoring. The global wearable technology market is expected to grow to 392 B$ by 2030 with CAGR of 13.9%. The opportunity is significant as the number of wearable users currently exceeds 1 billion globally and the developed technology targets similar markets.  We currently estimate that with the new instrument and digital biomarkers we can reduce the healthcare burden by over 30% by preventing CVDs. Additionally, we are aiming to identify citizens at risk of developing hypertension, CKD and/or HF and by timely intervention, we expect to reduce indirect healthcare costs by over 20%.  In conclusion, our solution will integrate two existing state-of-the-art methods and provide clearly new monitoring techniques to assess the microcirculatory st
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Development of hybrid modelling tools (knowledge driven and data driven) for simulation and optimisation of chemical processes', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

Reactor technology is a key technology, not only for the chemical and pharmaceutical industry, but also for the society as a whole. Reactor technology concerns the design of reactors. The choice of reactor, i.e. type and operation conditions, determines the effectiveness of the overall production process. A good reactor design offers high yield and selectivity and optimal performance with respect to environment and safety. E.g. raw material and energy consumption and waste production are effected by a proper reactor design. To satisfy the increasing demand for improved performance (higher throughput, higher selectivity, higher product quality, reduction of impurities, etc.) of existing (and new) processes, new powerful simulation tools have to be developed.The research within the training program aims at developing reactor models that are based on:1. Knowledge based models', i.e. based on accepted mathematical descriptions of the 'laws of nature' such as conservation of mass, thermodynamics, kinetics, chemical physical properties of the involved compounds and so on;2. Data driven models', i.e. based on Artificial Neural Networks, Fuzzy Logic and Genetic Algorithms, which define input-output relations on measured data only. The expectation is that the predictive power of the to be developed hybrid models will be higher than state-of the-art models resulting in better process control and improved performance at lower costs.The research work comprises1 ) the building of descriptive models,2) the collection of chemical physical data as well as of3) the collection of real process data in order to4) validate and improve the developed model.A team of experts from different areas including as process engineers. Mathematical experts and modeling specialists will guide the fellow