RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Identifying Constraints: Ancient protein characterisation to Reveal past Human Subsistence adaptations to climate change' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

Facing the constraints imposed due to climate change is a challenge past human societies had to take into consideration, similar to how current societies are facing global changes in resource availability and climate change. By looking into the past and how ancient societies adapted to temperature increase and water availability decrease could help us to innovatively deal with the current climate crisis. In the Levant, where cattle, pigs, sheep and goat have been domesticated, ecological constraints are one of the major reasons for observed changes in subsistence strategies. Traditionally, comparative anatomy of fauna remains is the methodology of choice when aiming to reconstruct past subsistence strategies. But in arid environments, archaeological bones and teeth degrades rapidly, leading to highly fragmented and poorly preserved remains, thus largely restricting faunal spectra reconstruction. This project offers a glimpse at past Levantine societies adaptation to climatic pressures by using the new and exciting field of palaeoproteomics. The fellowship will concentrate on three defined scientific objectives: 1. enhance the available protein reference sequences, crucially lacking Near-Eastern wild ungulates species; 2. identify subsistence strategy shifts along four Jordanian archaeological sites, each containing well-established stratigraphies, using ancient proteins based species identification; and 3. recover information regarding sex-driven husbandry practices in caprine herds using the new method of enamel proteome sexing. The combination of archaeology and biological sciences within the frame of ICARHUS will give the opportunity to get a glimpse into past human societies agro-cultural behaviour using methodological developments of use beyond the field of bio-arc
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Oil spill detection and monitoring in the European Union Mediterranean and South West Atlantic coastal areas' (1994-1998).

assistant: **Innovation**

General Information:  The 5th Environmental Action Plan targets prevention of pollution in marine waters, emphasising prevention at source. Specific actions related to this aim focus on environmental damage from shipping and surveillance of high-risk areas with appropriate monitoring techniques. In the context of the pilot areas of this project being sensitive, and in view of the lack of existing effective monitoring, the aims and objectives of this proposal, which match those of the CEO in general, are highly relevant in pursuit of the Plan.  The main aim of this project, therefore, is to process, disseminate and archive in a specifically designed database, near real-time information detailing specific oil pollution derived from satellite-based radar imagery for 4 high-risk pilot areas in the Western Mediterranean/Eastern Atlantic.  In addition a parallel activity will collate historical 95-96 oil pollution event information into the database to provide a valuable source of information to policy makers.  The project has been deliberately sized at the Western European level, however the approach now proven is directly transferable to the Eastern Mediterranean region and indeed to other seas.  A balanced project team was co-ordinated by CETEMAR (ES) and provided a dynamic mix of commercial and research organisations to undertake the pilot-project activity.  A team from Spain, Portugal, France, and Italy has been brought together to provide both direct and indirect access to end users.  EOS (GB) have previously been involved in similar activities in Northern Europe and provide an essential technology transfer component to the project.  An important aspect is the fact that the proposed pre-operational methodology has been based on an assessment of user requirements gathere
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Gene expression dosage as a driver of cellular and physiological traits' (DOSAGE2FUNC), addressing dissemination and exploitation.

assistant: **Impact**

The expression dosage of a gene is a fundamental determinant of its downstream function at the cellular and organismal level, and its genetic or environmental perturbations are a driving force of most common and rare disease in humans. However, we have limited understanding of the specific shape of dosage-to function-curves for human genes, what factors and mechanisms drive their variation across genes, phenotypes and cellular contexts, and how this contributes to functional architecture of human traits. This project addresses these questions using large human genetic data sets and cutting-edge experimental approaches. Using blood cell traits as our study system, we will characterize the relationship between gene dosage and cellular and physiological function in in unprecedented scale and depth. This addresses fundamental questions in systems biology and produces insights that can also benefit genomic medicine and drug development.   The Work Packages of this study will: 1) Establish the dosage-to-function relationship for hundreds of human genes, associating genetically driven gene dosage to blood cell traits in large human genetic data, and by an innovative CRISPR-based experimental approach that maps gene dosage changes to multiple cellular phenotypes; 2) Elucidate how cellular the dosage-to-cellular-function relationships differ between cellular states, and use single-cell RNA sequencing to analyze how regulatory networks mediate context-specific dosage-to-function effects; 3) Characterize upstream genomic and environmental regulators of gene dosage.   This project will build the first comprehensive, generalizable picture of gene dosage-to-function relationships in humans. Our analysis will link these insights to functional architecture of human traits, providing un
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Bio-Inspired Self-Assembled Supramolecular Organic Nanostructures' (BISON).

assistant: **Innovation**

Peptide building blocks serve as very attractive bio-inspired elements in nanotechnology owing to their controlled self-assembly, inherent biocompatibility, chemical versatility, biological recognition abilities and facile synthesis. We have demonstrated the ability of remarkably simple aromatic peptides to form well-ordered nanostructures of exceptional physical properties. By taking inspiration from the minimal recognition modules used by nature to mediate coordinated processes of self-assembly, we have developed building blocks that form well-ordered nanostructures. The compact design of the building blocks, and therefore, the unique structural organization, resulted in metallic-like Young's modulus, blue luminescence due to quantum confinement, and notable piezoelectric properties. The goal of this proposal is to develop two new fronts for bio-inspired building block repertoire along with co-assembly to provide new avenues for organic nanotechnology. This will combine our vast experience in the assembly of aromatic peptides together with additional structural modules from nature. The new entities will be developed by exploiting the design principles of small aromatic building blocks to arrive at the smallest possible module that form super helical assembly based on the coiled coil motifs and establishing peptide nucleic acids based systems to combine the worlds of peptide and DNA nanotechnologies. The proposed research will combine extensive design and synthesis effort to provide a very diverse collection of novel buildings blocks and determination of their self-assembly process, followed by broad chemical, physical, and biological characterization of the nanostructures. Furthermore, effort will be made to establish supramolecular co-polymer systems to extend the mo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Intelligent corrosion management underpinned by advanced engineering science'.

assistant: **Innovation**

Our planet’s population will continue to grow rapidly; between 2010 and 2025 the population will grow by 1.1bn. Urbanisation and growth of the consumer class in developing countries will lead to unprecedented demands on energy. There is arguably no bigger challenge to society than ensuring the security of affordable and environmentally-sustainable energy.  Hydrocarbons will provide a large proportion of the world’s energy for the foreseeable future.  There is no escape from the critically low oil price worldwide. Innovation becomes important in this price environment.  “Easy” oil has already been found; future supply will come from complex reservoirs requiring enhanced oil recovery (EOR).  There is a massive growth in renewables technology; the EU is making steady progress towards its 2020 target. The EU renewables energy share increased from 8% to 15% in the decade to 2013.  Energy supply and consumption brings with it the global issue of climate change as emissions from industry and transport increase.  Inextricably linked to energy is the reduction of the global carbon footprint and Carbon Capture and Storage (CCS) offers the only real technology that can handle the already produced carbon dioxide.Corrosion in energy and environmental control linking to energy supply provide the underpinning rationale for this proposal. Corrosion is one of the major life-limiting factors for energy supply (oil and gas, renewables, EOR) and in environmental pollution control (CCS) and is estimated to cost 3% GDP.  This proposal brings some of the most exciting experimental and modelling engineering science to create a framework for the intelligent management of corrosion. INTELLICORR will use synchrotron techniques, advanced microscopy, numerical methods and environmental/cost analysi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Innovative Digital Preservation using Social Search in Agent Environments' under Seventh Framework.

assistant: **Concept**

Digital preservation (DP) represents the management of digital information over time to guarantee their accessibility and preserved quality. It includes processes and activities that ensure access to information and all types of records, scientific and cultural heritage that is stored in digital formats. Digital preservation offers assurance that digital information can be accessed continuously at any time and across shifts of technical generations that occur approximately every 5 to 15 years.We propose the DURAFILE platform that can be defined as a platform made by intelligent agents that exchanges dynamic knowledge and information among them (as a type of social search) with the goal of finding suitable preservation plans for obsolete multimedia digital objects. This represents a complete solution for multimedia digital preservation, that is extensible and flexible, always up-to-date as the information it contains is alive and real time accessible. DURAFILE can ensure that their information will remain available in the future, no matter how the technology evolves or current data formats become obsolete. The DURAFILE social features represent a unique approach to digital preservation as the knowledge base grows with its usage. .DURAFILE will improve the competitiveness of the European economy in several ways: 1) Tapping into a huge market potential due to the vast potential user list and exponential growth of digital data 2) First-mover advantage in comparison to non-European countries that are not using DURAFILE.DURAFILE will be available as a) web application to scan the files for professional users, including big institutions or SMEs that need to handle a large amount of information that needs to be preserved, b) downloadable client to scan locally as the most commo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Microreactor-assisted Maillard reaction to valorise rapeseed cake protein for the production of plant protein emulsion beverages' (MiMaPro) targeting Horizon Europe.

assistant: **Abstract**

The substantial amount of agro-industrial by-products, such as rapeseed cake, poses an environmental concern in the EU. MiMaPro is a multidisciplinary project that aims to valorise rapeseed cake by modifying the structure of rapeseed cake protein (RCP) and enhancing its value as a plant protein beverage, both in the laboratory and pilot-scales. This strategy aligns with the EU's Circular Economy Action Plan and meets consumer demand for plant-based diets. Novel approaches will address techno-functional challenges, including low solubility and emulsification of RCP:a) Microreactor-Assisted Maillard: MiMaPro's originality lies in improving the techno-functional properties of RCP by employing a microreactor-assisted Maillard reaction to create conjugated RCP. A microreactor will be used to accelerate the reaction while managing the progression to advanced glycation, finally improving solubility and emulsification.b) Spray Drying: MiMaPro will employ optimised spray drying (as a scalable process) to produce Maillard conjugated RCP powders with minimal variation from freeze-dried powder.c) Emulsion Creation: Conjugated RCP will be partially blended with pea protein to create a hybrid protein with a balanced amino acid profile. An emulsion stabilised by this blended conjugated RCP-pea protein will be prepared, followed by kinetic stability determination and bioavailability assessment of emulsion-loaded vitamin D3.d) Upscaling and Prototype Generation: MiMaPro will scale up the microreactor and spray drying based on the knowledge gained from steps a-c to produce a plant protein emulsion beverage prototype.The majority of MiMaPro will be conducted at UL (host). The fellow will participate in a secondment at Ulster University to study vitamin D3 bioavailability and undertake an
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Recycling carbon dioxide in the cement industry to produce added-value additives: a step towards a CO2 circular economy' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

CO2 from the flue gases of a rotary kiln in a cement industry (CO2: 25 vol%) will be used for the production of value-added chemicals (acid additives for cement formulations) and materials (CaCO3 nanoparticles to be used as concrete fillers). A circular-economy-approach is enabled: the CO2 produced by cement manufacturing is re-used in a significant part within the plant itself to produce better cement-related products entailing less energy intensity and related CO2 emissions by a quadratic effect.Ionic liquids (bare or amine-functionalised) will be the key technological playground for the efficient and cost-effective (<30 €/ton) purification of CO2 to a purity grade sufficient for the above mentioned utilisation paths. A dedicated pilot plant (flue gas flow rate: 50 Nm3/h) will be developed, based on the knowledge-based selection of the best ionic-liquids composition and operating conditions.Within a final TRL 6 integrated system demo campaign, the thereby derived CO2 will be utilised in parallel to: -) promote the precipitation of nano-CaCO3 powders which act as strength enhancer and accelerator of the hydration rate.-) synthesize through electrocatalytic and catalytic pathways formic acid, oxalic acid and glycine to be used as hardening acceleration promoters, grinding aids or ionic liquids additives, respectively. Distinctive features of the RECODE approach are the high process intensification and scale-up-ability; the use of low-grade heat sources; the meaningful reduction of CO2 emissions (>20% accounting for direct and indirect means) and the good market potential of their products at a mass production scale.The first two years of the project will be focused on the development of key functional materials and process units at TRL 4-5, the third year on the assembl
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'WoodJam—Sediment dynamics of instream wood jams and managed installations' (WoodJam).

assistant: **Innovation**

Natural flood management practices, including engineered logjam installations, can slow floodwaters in upstream catchments, promoting infiltration and reducing flood severity.  In order to reduce flood damages and prepare for an expected increase in severe floods due to climate change, the EU Water Framework Directive encourages the use of engineered logjams and other natural flood management interventions. It is necessary to consider the effects of channel-spanning engineered log jam installations, which are the most common, on stream hydrodynamics and sediment scour and retention in order to guide management interventions and accurately assess the implications of natural flood management projects. The proposed project objectives will fill existing knowledge gaps related to the quantification of logjam-induced sediment storage and flow resistance, in addition to the prediction of the length over which an engineered logjam influences the downstream river channel. WoodJam will experimentally investigate the impact of jam geometry and spacing on sediment storage and develop a method to assess the porosity of a jam without disassembly. Experimental studies conducted in sediment flumes at Cardiff University will be related to observations of existing natural flood management projects in the UK and Germany, with design and management recommendations transferred to environmental resource managers through discussion and policy documents. Hydraulic modelling studies will identify methods to represent common engineered logjam designs in 2D flood modelling tools, validated by experimental results. These methods will enable accurate modelling of natural flood management project effects. The project approach will provide an innovative approach by uniting CU expertise in LW hydrauli
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Rapid determination of organic microcontaminants in the water/sedimentinterface layer using fast extraction procedures with subsequent gc- - tandem-ms analysis' to be submitted under Fourth Framework.

assistant: **Abstract**

Research objectives and content The increasing concern about the environment and its pollution has led to the development of analytical techniques for the determination of organic micropollutants at adequate levels desired by, e. g. EU directives. However, the demand for trace-level analyte determination in the various compartments in the environment, and the growing amount of samples, require a novel strategies such integrated sample handling and chromatographic techniques. The need for unambiguous structural identification request very sophisticated detection. In the study proposed here, analytical systems will be optimized and applied to samples rather from the top layer of river sediments. This part of the aquatic is especially interesting, because (i) the concentration c even polar and good-water soluble analytes are commonly much higher than in the water (which is more frequently analyzed), (ii) it hosts many biota (e.g. worms, plants, fish; but also microorganisms) which makes it a region for bioaccumulation, biodegradation as long as bioavailability is present, and (iii) scientific interest (analyte concentration; distribution between water and solid compartments). The analytical system will be based on the on-line/at-line combination of a sample preparation modules, i.e. solid-phase extraction for water while in-vial extraction and MASE are used for water and solid sample The combination of integrated sample preparation with gas chromatography with sensitive and selective MS, MS/MS and AED detection, will permit a sample reduction from typically 40 g to less than lg. This will require optimization of large-volume techniques. The practicality of the proposed procedures will be demonstrated for different types of real-life sediments. Target analytes are mainly (o