RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Efficient Co-Electrolyser for Efficient Renewable Energy Storage - ECo' to be submitted under Horizon 2020.

assistant: **Abstract**

The overall goal of ECo is to develop and validate a highly efficient co-electrolysis process for conversion of excess renewable electricity into distributable and storable hydrocarbons via simultaneous electrolysis of steam and CO2 through SOEC (Solid Oxide Electrolysis Cells) thus moving the technology from technology readiness level (TRL) 3 to 5.In relation to the work program, ECo will specifically:• Develop and prove improved solid oxide cells (SOEC) based on novel cell structure including electrode backbone structures and infiltration and design of electrolyte/electrode interfaces to achieve high performances and high efficiencies at ~100 oC lower operating temperatures than state-of-the-art in order to reduce thermally activated degradation processes, to improve integration with hydrocarbon production, and to reduce overall costs.• Investigate durability under realistic co-electrolysis operating conditions that include dynamic electricity input from fluctuating sources with the aim to achieve degradation rates below 1%/1000 h at stack level under relevant operating conditions.• Design a plant to integrate the co-electrolysis with fluctuating electricity input and catalytic processes for hydrocarbon production, with special emphasis on methanation (considering both external and internal) and perform selected validation tests under the thus needed operating conditions.• Test a co-electrolysis system under realistic conditions for final validation of the obtained results at larger scale.• Demonstrate economic viability for overall process efficiencies exceeding 60% using results obtained in the project for the case of storage media such as methane and compare to traditional technologies with the aim to identify critical performance parameters that have to be improve
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Autonomous Robots with Common Sense'.

assistant: **Concept**

Autonomous robots such as autonomous vehicles cars and drones have the potential to revolutionize the way we work and live. Unfortunately, current autonomous robots do not have common sense and may enter a catastrophic condition called loss-of-control after failures. The ultimate goal of this research is to enable a new generation of autonomous robots that are aware of their physical capabilities and limitations, allowing them to act with common sense after failures. To achieve this I propose a new paradigm in autonomous robot control: Artificial Physical Awareness (APA). APA requires accurate real-time knowledge of the time-varying stochastic safe envelope which is a subset of the state-space inside which safe operations of the autonomous robot can be guaranteed. The safe envelope is stochastic and time-varying; it contains uncertainties and will shrink after failures, reflecting the reduced post-failure performance of the autonomous robot.Obtaining and utilizing the time-varying stochastic safe envelope in real-time represents a currently unsolved scientific challenge for the following reasons: 1) the safe envelope cannot be measured directly; 2) current safe envelope computation methods are real-time intractable and/or do not take into account uncertainties; and 3) no control methodology exists that allows for time-varying safe-envelope informed balancing of safety and performance.This multidisciplinary research combines new insights in time-varying stochastic state reachability analysis, tipping-point forecasting, bio-inspired envelope sensing and recovery, and nonlinear fault-tolerant control to develop the new APA-autopilot system, which is the main output of this research. This research project has the potential to lead to a revolution in autonomous robot design,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Control of Heterogeneous Automation Systems:\nTechnologies for scalability, reconfigurability and security' (CHAT).

assistant: **Innovation**

Scalability, reconfigurability, and security are three aspects of paramount importance in developing efficient, predictable and safe control architectures for large-scale networked industrial automation.  <br/><br/>CHAT is about developing core components (algorithms, protocols and procedures) of the next-generation of distributed control systems, able to tackle the supervision and control of larger and more complex plants while drastically reducing infrastructure, maintenance and reconfiguration costs. The concept at the core of CHAT is that of an embedded control design space, where fundamental research questions on the performance achievable by a certain subsystem with a given quality of networked control, can be formalized and investigated.  The general goal is to encapsulate subsystems in automation components integrating seamlessly into more abstract levels of the Distributed Control architecture: the challenge is to evaluate what is the exact amount of decentralized control capabilities to be embedded in the component, which makes modularization and abstraction possible.<br/><br/>The daring ambition of the methodology to be developed in CHAT is to provide a unified approach to a variety of problems arising in industrial automation and beyond, ranging from process control to manufacturing supervision. However, the project is grounded in a very concrete setting and centred on the industrial case of paper factories, where large-scale networked automation is integrated from the initial continuous process control stage through the end-of-line manufacturing and warehousing of consumer products.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'The brucella 28kda protein of the cytosoluble protein extract as diagnostic antigen for the differentiation between infected and vaccinated animals' (1994-1998).

assistant: **Innovation**

AR 28 klDa protein of Brucella has been shown to induce antibody response in infected sheep not detected in vaccinated animals. This makes this protein an interesting candidate for a brucellosis diagnostic test ailowing the differentiation between infected and vaccinated animals something difficult with the current serological tests usually detecting anti-LPS antibodies that are generated in both infected and vaccinated animals. These antibodies are also responsible for cross-reactions with other microorganisms . The objectives are: - To evaluate the interest of the recombinant protein for the specific diagnosis of brucellosis and serological differentiation between infection and vaccination in sheep and cow. - Construction of vaccinal mutant strains not expressing the protein. Vaccination with these mutants would improve the test effectiveness avoiding the detection of possible positive reactions among vaccinated animals. - To analyze, using the mouse model, the role of the protein in the protective activity and virulence of the vaccinal strains.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Replacement of hydrazine for orbital and launcher propulsion systems' (Rheform).

assistant: **Concept**

The project deals with the replacement of hydrazine within space propulsion systems. It improves significantly the ADN-based propellants currently existing and enables the replacement of hydrazine within the whole operational area of currently used hydrazine propulsion systems. The objectives of the project are:1.) Replacing hydrazine by adapting the propellant to currently existing materials available in Europe2.) Development of a cold-start capable ignition system to replace hydrazine in the whole operational area3.) Verification of the technology within battleship unit(s) to reach a Technology Readiness Level of 5 4.) Adapted numerical models to describe the processes within such propulsion systems. To reach these objectives, the following development will be done within the projectA) Propellant development in order to obtain maximal temperatures within the combustion chamber that can be withstand with currently available materials in Europe. Additionally, the propellant will have increased specific impulses in relation to hydrazine.B) Development of catalytic ignition systems to withstand the thermal and mechanical shocks while having cold-start capabilityC) Design and testing of the corresponding battleship units within the project to verify the achievement of the project experimentally (reach TRL of 5)D) Generating validation results for future purposes to adapt the technology to future purposes. Therefore, the relation to the work programme ""Alternative to hydrazine in Europe"" is achieved by a replacement of the currently hydrazine based propulsion system with a green propellant system with higher specific impulse.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Chronotype, health and family: The role of biology, socio- and natural environment and their interaction' (CHRONO).

assistant: **Concept**

The widespread use of electronic devices, artificial light and rise of the 24-hour economy means that more individuals experience disruption of their chronotype, which is the natural circadian rhythm that regulates sleep and activity levels. The natural and medical sciences focus on the natural environment (e.g., light exposure), genetics, biology and health consequences, whereas the social sciences have largely explored the socio-environment (e.g., working regulations) and psychological and familial consequences of nonstandard work schedules. For the first time CHRONO bridges these disparate disciplines to ask: What is the role of biology, the natural and socio-environment and their interaction on predicting and understanding resilience to chronotype disruption and how does this in turn impact an individual’s health (sleep, cancer, obesity, digestive problems) and family (partnership, children) outcomes? I propose to: (1) develop a multifactor interdisciplinary theoretical model; (2) disrupt data collection by crowdsourcing a sociogenomic dataset with novel measures; (3) discover and validate with informed machine learning innovative measures of chronotype (molecular genetic, accelerometer, microbiome, patient-record, self-reported) and the natural and socio-environment; (4) ask fundamentally new substantive questions to determine how chronotype disruption influences health and family outcomes and, via Biology x Environment interaction (BxE), whether this is moderated by the natural or socio-environment; and, (5) develop new statistical models and methods to cope with contentious issues, answer longitudinal questions and engage in novel quasi-experiments (e.g., policy and life course changes) to transcend description to identify endogenous factors and causal mechanisms
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'New methodologies to synthetise unnatural nucleosides, known and putative antiproliferative agents' will create measurable scientific, societal and economic impact aligned with Sixth Framework.

assistant: **Impact**

Dr Migaud and colleagues, all academic medicinal synthetic chemists at Queen's University Belfast (Northern Ireland, academic partner), in collaboration with GlaxoSmithKline (Stevenage, UK, Industrial partner via Dr McDonald) seek financial support to host an Early Stage Research Training programme for four post-graduate researchers (36 months each) who would pursue a PhD training programme in Organic and Medicinal Chemistry at QUB/GSK and for the equivalent of four visiting EST fellows (12 months each) enrolled in a PhD programme in another EU or affiliated state university.The principal objective of the proposed activities is to develop a unique environment for innovative training of chemists in order to facilitate their integration to the ever-evolving world of interdisciplinary research at the Pharmaceutics and Life Science interface.To achieve excellence in interdisciplinary research of this type, hands-on and taught training activities will maximise acquisition of expertise in the fields of organic synthesis, medicinal chemistry, enzymology, biology and biotechnology, to help the fellows attain fundamental understanding in:- Design of inhibitors and/or ligands based on structural knowledge - Development of organic synthetic methodologies- Analysis of biological results and iterative design of new compounds- Prediction of biological activities based on structural data- Design of antiproliferative agents based on pharmacodynamics, pharmacokinetics and toxicological results.The collaboration between QUB and GSK achieved through this programme will also maximise the transfer of research competencies between the academically-based medicinal chemistry research laboratories where synthetic methodologies are devised and the pharmaceutical industry where high through-put a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Evaluating the performance of local climate policies in Mexico (2009-2018)' (2009-2018).

assistant: **Concept**

Climate policy has been under negotiation at international level for more than twenty years. During this period, mitigation efforts and studies on implementation and governance of climate policy have focused on industrialised countries, paying little focus to emerging economies. Recently domestic laws have started to be enacted worldwide stemming from this international debate. In this context, efforts to mitigate climate change require ambitious long-term policies and commitments; however domestic public agendas are prone to modifications by changes in public administration after every election, thus creating the risk of ineffective implementation. The study of the socio-economical and political dynamics affecting the design and paths followed by climate policy fit the Horizon 2020 programme on Societal Challenges. The objective of the project “Evaluating the performance of local climate policies in Mexico (2009-2018)” (e-Lection) is to assess what are the determinants of the diffusion and successful implementation of climate policy at local jurisdictions. This research takes an in-depth look into climate governance and policy implementation in Mexico as an example of an emerging and democratic major economy actively involved in climate policy. It offers an excellent example for this purpose since it has stated publicly its climate policy goals since 2008. Mexico with its 32 federal entities and around 2470 municipalities offers a vast laboratory for studying the different factors that determine continued implementation of domestic climate policy over the last decade. The contrasting contexts in which implementation takes place in Mexico offer a comprehensive view that will provide valuable information to policy-makers locally and globally. The U.K has a long-standing
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Super-resolution visualisation and manipulation of metaphase chromosomes' (CHROMAVISION).

assistant: **Innovation**

CHROMAVISION aims to develop a pioneering chromosome imaging and manipulation platform that will fuel the next decades of structural chromosome research. Chromosomal abnormalities are characteristic of many disorders such as cancer, impaired fertility due to maternal aging, and neurological disorders such as fragile X syndrome. If humanity is to fully understand the wide range of diseases that are associated to errors in cell division, we must be able to further 'zoom in' on healthy and diseased chromosomes in all their complexity. The CHROMAVISION platform will allow molecular biologists to automatically isolate individual chromosomes from small tissue or cell samples and have these delivered to a super-resolution microscope. Chromosome isolation and delivery is achieved by an opto-fluidic chip that is able to trap, visualise and lyse individual cells and separate metaphase chromosomes from cell lysate. Single chromosomes can be “hand-selected” and brought into focus of the Super-Resolution Correlative Tweezers Fluorescence Microscope (CTFM-SR3D) that is developed in CHROMAVISION. This instrument will for the first time enable 3D, super-resolution, real-time metaphase chromosome observation and manipulation studies under near-physiological conditions. The technique will push the boundaries of what is currently possible in microfluidics and super-resolution microscopy and combine these into a single powerful approach for chromosome studies. Furthermore, the platform will be applied in CHROMAVISION to address key challenges in clinical and fundamental chromosome research, potentially resulting in breakthrough discoveries. Better imaging and understanding of the chromosomal mechanisms will contribute to our knowledge of the etiology of human diseases and aid drug discover
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'Environmental and climatic records from high elevation'.

assistant: **Concept**

The general objective of this proposal - Environmental and Climate records from High Elevation Alpine Glaciers (ALPCLIM) - embraces the aquisition, evaluation and validation of climatic relevant ice core records from cold Alpine glaciers along with the prospecting of the potential of these unique archives for climatic studies. This includes the recovering of representative high resolution ice core records from several drill sites in the. Monte Rosa and Mont Blanc summit region, partly entering far into the pre-industrial era and generally refering to the following ice core signals: - isotope-temperature changes - aerosol related species (sulphate, nitrate, ammonium, mineral dust) as well as - long lived trace gases (methane, carbon monoxide) and combustion aerosol components (black carbon, DOC) not investigated yet in Alpine ice cores The evaluation of these records is focussed on the assessment of their significance in reflecting net atmospheric changes against the respective variability during the pre-industrial era. This challenge dictates a thorough investigation of glaciological aspects of cold Alpine glaciers in view of their sampling characteristics and climatic evidence for the englacial temperature distribution which is performed by field observation and modelling. Constraining the climatic significance of the climatic ice core proxy records is attempted by decoding the englacial borehole temperature as well as by assimilating long term precipitation and temperature records from relevant instrumental archives. The project is based on teams specialized in glacio-chemistry, environmental isotopes, Alpine glaciology as well as Alpine climatology. The proposed ice core activities are mainly based on recently drilled deep ice cores.