RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Improved Novel Eco-Friendly Bleaching System for Cotton Using Enzyme and Ultrasound Processes' under Seventh Framework.

assistant: **Concept**

Cotton textiles --the main natural-fibre textile used worldwide-- undergo a toxic and costly bleaching process that weighs heavily on the quality, cost and environmental impact of textile manufacture. CottonBleach proposes the development of an improved cotton bleaching technology, more respectful with the textiles and the environment, to improve the competitive edge of European textile SMEs. Current bleaching methods use hydrogen peroxide (H2O2) and sodium hypochlorite (NaClO, aka bleach), resulting in fabric damage, formation of toxic by-products and large amounts of water and energy to remove these chemicals. The proposed CottonBleach technology offers a non-toxic Totally Chlorine Free (TCF) bleaching technology using a combination of sequential enzymatic techniques enhanced through the use of ultrasound technology. This innovative technology will maintain the natural strength of the cotton fibre, providing significantly improved bleaching effectiveness with minimal fibre damage. The scientific objective of CottonBleach is to further investigate the use of ultrasound-enhanced enzymatic bleaching on an industrial scale of development, as manifested by recently published economic analysis which consider the use of enzymes as “cost effective for textile mills to adopt”. This proposal also fulfils the objectives of FP7 collective research in that it will expand the knowledge base of large communities of SMEs and develop innovative technology that has potential applications in the broader bleaching industry.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Functional food ingredients against colorectal cancer - development of a genomics and proteomics based screening assay' (FFACC), addressing dissemination and exploitation.

assistant: **Impact**

More than half of the gastrointestinal tract cancers may be related to the diet. Research to identify active components in the diet reducing the cancer risk, to understand the mechanism of cancer prevention and (the last few years) to design functional foods with the specific goal to reduce the incidence of cancers has made considerable progress. However, a systematic search for effective (combinations of) food compounds or ingredients has not been performed, primarily due to lack of good methodology. An (in vitro) bioassay will be developed, based on genomic and proteomic changes in colorectal cells, to assess the efficacy of (functional) food ingredients in prevention or inhibition of the development of early stages of colorectal cancer. The genomic and proteomic changes in colorectal cells will be powerful biomarkers of colon carcinogenesis as a large portfolio of genes and proteins are tested simultaneously and the assays are easy to perform.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'DNA-based tests for commercial medicinal plant authentication', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

The unambiguous identification of plant raw material is a crucial step in the quality control of medicinal plants in order to guarantee the identity and a constant and reliable quality of the starting material. Apart from the classical pharmacognostic methods, phytochemical methods (often based on chromatography) are used for this purpose. However, these methods often fail to provide secure results, especially when only single plant parts are available, and therefore, there is a need for novel and more reliable methods. DNA-based identification methods are becoming increasingly relevant in this respect and have much potential to be powerful additions to the classical techniques.Using the medicinal plant Rhodiola rosea as an example, this project has the following objectives:a. To develop a sensitive, quantitative DNA-based test to distinguish Rhodiola rosea  plant material from related plant species, and to detect low level contamination by these potential adulterantsb. To introduce the DNA test for Rhodiola authentication into the QC procedures of the commercial partnerc. To develop phytochemical and pharmacognostic methods to detect low level contamination of Rhodiola rosea plant material by potential adulterant plant speciesd. To determine the feasibility of incorporating DNA-based tests for a range of plants into the industrial partner’s quality control procedures.e. To identify the most appropriate strategy and technology platform for DNA-based tests for recommendation as an industry standard for regulation and quality assurance.These objectives will be acheived by a synergistic partnership between a university molecular biologicial research group and a phytopharmaceutical company, designed to fully exploit the opportunities for secondment and training provided by
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Aerospace Composites digitally sensorised from manufacturing to end-of-life' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

INFINITE aims to develop sensors and analyser based on the usage of ferromagnetic microwires to be embedded in aerospace composite structural parts, in order to monitor manufacturing and structural health throughout the whole life cycle of the component. The wireless monitoring system will permit producing digital signals and vast sets of data linked with the specimen to create an as-built digital twin of the structure that will also account for the whole history since it was manufactured through all maintenance operations performed, until being optimally recycled. INFINITE intends to deliver improvements in composite manufacturing and structural health monitoring (SHM) by the development of functional sensorised Non-Crimp fabrics (NCF). These fabrics will provide an efficient real-time monitoring system through a self-sensing fibre by wireless monitoring of the fibre position, orientation, strain-stress and temperature. This will be achieved by applying a safe magnetic signal, providing a volumetric information during the manufacture process (temperature and fibre control) but also during the life of the component. In service, the new SHM system will provide information about component integrity, performance and safety; therefore informing and improving maintenance operations. The new sensorised NCF will also enable a new repair capability for complex parts. Integration of microwires in the fabric opens new possibilities in the design of future functional composites using existing sensoring technologies. This advanced quality monitoring has the potential to deliver a significant impact on cost and safety reliability of composite components, providing a competitive advantage of European manufactures and MROs. INFINITE also aims to assess the effect of sensoring hardware
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Establishing in-depth services enhancing the innovation management capacity of South West of France SMEs in 2019' (2014-2020), addressing dissemination and exploitation.

assistant: **Impact**

The project involves 3 partners of the Enterprise Europe Network South West France consortium which covers the region Nouvelle-Aquitaine and the Midi-Pyrénées territory. The general objective is to contribute to raise the competitiveness of SMEs from this area by offering support services in the area of innovation management. The project will also contribute to develop more efficient and more effective innovation processes and higher quality innovation management capacity assessment and support services. The support will be delivered as service packages to 2 groups of SMEs: a) Beneficiaries of the Horizon 2020 SME Instrument, Fast Track to Innovation and Future Emerging Technologies Open: to enhance the probability of a successful exploitation of the innovation project results and lead to the sustainable growth of the beneficiary beyond the participation in Horizon 2020. The support service will pinpoint weaknesses in the innovation capacities of the beneficiary, select suitable coaches to address the identified weaknesses and monitor the coach-client relationship and to accompany the beneficiary through the SME instrument project b) SMEs with significant innovation activities and a high potential for internationalisation: to enhance their innovation management capacities to be able to gain new international markets and leaderships. The support service will consist in an in-depth innovation assessment in order to develop and implement a tailored action plan to improve the SMEs capacity to manage innovation processes. The partners will use dedicated assessment tools: IMP3rove, Check’Innov and Innovation Way. The project will last 12 months and will provide 63 support service packages.


**Keywords:** SME, Innovation management, SME instrument, SME support, funding, Europ
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Fostering local energy investments in the Province of Matera' (FESTA).

assistant: **Innovation**

FESTA has the overall objective to foster local energy investments on public buildings (primarily in schools, a significant target in Italy for energy efficiency) and to spread the PPP approach also through the innovative, for the context, Energy Performance Contracts (EPC) in convergence regions. The main specific objectives of the proposed action are:1. to define technical, financial, legal and administrative specifications of a package of investments that are economically sustainable and attractive for private investors;2. to assess a PPP scheme and to define an EPC model for the energy efficiency of public buildings, also to create better condition to renewal this aged (> 30 years) buildings;3. to publish the call for tender and to procure the bundled investments through EPC and sign the investment contracts;4. to become a best practice for the mobilisation of local energy investments of the area where municipalities are preparing the SEAPs (Province of Matera – leader of this project – is the coordinator);5. to share all this advances with local actors and other MLEI European partners.  Specifically, the project (regarding a complex of schools in Matera and in Policoro with the neighboring hospital) aims to experiment, with technological and method approaches, the achievement of the objective that all schools in the area become “climate neutral” by 2020.The project also aim to generate capacity building in the field of renewable energy and energy saving through:• the inter-institutional collaboration between different public authorities to increase the interventions scale (that is very important considering both the small average size of the local administrations and the low population density);• the development of approaches that pay special attention to the poten
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Skin Tissue INTegrity under Shear' to be submitted under Horizon 2020.

assistant: **Abstract**

The mechanical, chemical and biological properties of human skin may be challenged when in contact with another surface e.g. immobilized persons supported on a bed or in a wheelchair, amputees wearing a prosthesis, and individuals with orthoses or functional medical devices attached to the skin. This can result pressure ulcers, particularly in the elderly and those with comorbidities such as diabetes. Skin condition is also critical during interactions with personal care products such as creams, shavers, grooming devices, therapeutic lamps or massage equipment, which can result in various forms of irritation. The main scientific aim of STINTS is to understand the complex biomechanical and biochemical pathways leading to loss of skin integrity, following the exposure of the skin to prolonged pressure and shear forces that ultimately result in damage at the cellular level. The objective is to reduce the huge societal and financial costs of pressure ulcers by improving (a) the design of more effective preventative aids (mattresses, shoe insoles, incontinence products etc.), (b) early stage diagnosis (non-invasive biomarkers and sensors, and smart materials) and (c) ultrasound therapy. The new understanding of skin behaviour will also be exploited by application to personal care products (razors that cause minimal skin irritation and skin creams with more efficacious skin hydration and barrier properties). These objectives will be achieved by the deployment of experts in multi-scale computer simulation, experimental cellular and tissue biomechanics, biophysical monitoring, sensor design, medical devices and materials, and clinical studies. STINTS will create an ambitious environment of supradisciplinary inter-sectoral research training for early stage researchers that combi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'World-wide E-infrastructure for structural biology'.

assistant: **Objectives**

The focus of structural biology is shifting from single macromolecules produced by simpler prokaryotic organisms, to the macromolecular machinery of higher organisms, including systems of central relevance for human health. Structural biologists are expert in one or more techniques. They now often need to use complementary techniques in which they are less expert. Instruct supports them in using multiple experimental techniques, and visiting multiple experimental facilities, within a single project.The Protein Data Bank is a public repository for the final structure. Journals require deposition as a precondition of publication. However, metadata is often incomplete.This project will pilot an infrastructure for storing and processing data that supports the growing use of combined techniques. There are some technique-specific pipelines for data analysis and structure determination. Little is available in terms of automated pipelines to handle integrated datasets. Integrated management of structural biology data from different techniques is lacking altogether.The proposed activity will integrate the data management facilities that already exist, and enable the provision of new ones. The resulting integration will provide users with an overview of the experiments performed at the different research infrastructures visited, and links to the different data stores. It will extend existing facilities for processing this data. As processing is performed, it will automatically capture metadata reflecting the history of the project. The effort will use existing metadata standards, and integrate with them new domain-specific metadata terms.This proposal will develop application level service specific to uses cases in structural biology, enabling structural biologists to get the ben
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Improvement of Ni-free White Gold Alloys' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

The experimental research work basically consisted in alloy development and required a well-defined frame, which based on literature data and data/experience available from the partners. In a first experimental phase, a screening testing programme was carried out on very small test pieces. This was aimed at a first overview on the most significant properties of the alloys, i.e. regarding colour, deformability, hardness and microstructure in various states. In the following phase which proceeded until the end of the first project year, more detailed investigations into the material/manufacturing properties of some selected alloys have been carried out at the laboratories of the R&D performers using larger quantities of material and larger sample sizes. From these investigations, the alloys with the most promising properties were recommended for application testing by the industrial partners, namely Mn- and Cr-based alloys (Pd-free and alloys with reduced Pd-content), as well as conventional Pd-based alloys containing grain refiners.During industrial testing the different steps/methods of jewellery production were followed at the SMEs using the new materials: production of semi-finished products, investment casting, mechanical fabrication of rings/chains, joining and refining/recycling. Grain refinement by Ir-additions proved to be highly beneficial for improving ductility, polishing and surface properties of jewellery products. Most important, however, it turned out that the newly developed Cr-alloy systems despite of several problems related with reactivity of the alloys with air and graphite, is highly interesting and would mean a lot of advantages in comparison with the developed Mn-alloys or other existing alternatives. In particular, the Cr-alloys possess excellent
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fifth Framework proposal for the project 'Methodological and experimental research centre and infrastructure for studies of global climate change impacts on forests'.

assistant: **Objectives**

The goal of the proposed project is to make an access of the Methodological and Experimental Research Centre and Infrastructure (MERCI) for community of EU researchers interested in the forest stand ecophysiology and impact of Global Climate Changes. The MERCI is constructed as a cluster of special tools used for the long-term research on the level of a forest stand. The capacity (up to 20%) of MERCI can be used for users from EU countries for their research. The users will be selected on the annual basis upon submitting project proposals evaluated by an Int. Sci. Committee. Because of the unique equipment of MERCI and a participation in EU R&TD programmes, international cooperation is expected.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'The Role of RANK and RANKL in breast cancer and metastasis generation of new mouse model for breast cancer research' goes beyond current state-of-the-art under Sixth Framework.

assistant: **Innovation**

Breast cancer is the second leading cause of cancer death in women after lung cancer. Breast cancers are frequently associated with bone metastasis resulting in severe disease burden pain, and death. Josef Penninger was the first to show that the Receptor-activator of NF-kB(RANK) and its ligand (RANKL) are essential for osteoclast differentiation, activation and survival, as well as for mammary gland development. In addition, expression of RANK was detected in various breast cancer cell lines. Stimulation of RAN KL via RANK directly triggers chemotactic migration of epithelial breast cancer, prostate cancer, and melanoma cellsRANKL further causes chemotaxis of primary mammary epithelial cells and osteoclasts.Our hypothesis is therefore that, RANK/RANKL play an important role in breast cancer and the inhibition of RANK/RANKL might be useful to abrogate metastasis of epithelial tumours to the bones. To better understand the molecular and cellular aspects of mammary tumours and metastasis as well as to test and develop new therapies we will analyse the complex role ofRANK/RANKL in breast cancer formation by crossing our existing RANK and RANKL knock-out mice into various transgenic mouse lines that develop breast cancers. A cell culture system will be established to study the molecular signalling cascades of RANK and RANKL, involved in cell migration and metastasis. Additionally, using a new tetraploid-G4 mouse ES celsystem we will set up a platform for the rapid generation of novel mouse models for breast cancer studies. The long-term goal is to contribute to the finding of additional methods and drugs to cure breast cancer.