RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Risk Based Technology for Blade Structural Assessment' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Wind energy is one of the fastest growing sectors in the world's energy markets. According to the EWEA, the European wind market it is expected to grow consistently at a compound annual growth rate of 9.8%. As annual blade failures are estimated at around 3,800 with poor maintenance the most common cause of accidents, ensuring the integrity of blades is a key issue with respect to the business, safety and the environment. The overall problem envisaged is the lack of effective condition monitoring systems for the blades, representing a business opportunity for the project’s partners Hence, the Project aims to commercialize a novel solution, BladeSave, marketed as a fusion between a Fibre Optic Structural Health Monitoring System providing multi-sensing capability and a management software incorporating risk based inspection data analysis and offering a comprehensive solution for blade monitoring, repair and management. Based on existing technologies developed by the partners at TRL6, BladeSave will assist WFOs in satisfying newly imposed regulations by the European Agency for Safety and Health at Work (amendments to EN 50308) and benefit European ISPs in the CM services market, giving them a competitive edge over global rivals. Our product market target consists predominantly of the WTFs installed before 2011 (currently around 71,620 in Europe) as old wind turbines have an average annual maintenance cost larger than newer models, are not covered by warranties and offer a bigger risk of catastrophic failures. The project brings together five experienced companies with a unique set of skills and expertise in the wind industry. BladeSave will have an impact on both European and foreign markets, and over the five year sales projection, we forecast a total cumulative gross pr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'InJection Networking actors in the medical device sector' (INJECTION).

assistant: **Concept**

The overall objective is to improve growth and innovation of European active medical device SMEs by identifying and assisting in removing the barriers to their innovation and growth, and then by providing relevant tools, services and networks. An important element is the dissemination of knowledge on the requirements of investors, so business development can be focused on communicating compelling and relevant investment opportunities, and accelerating the transition from research to revenue.In the first stage, existing areas of business innovation and financing will be identified and categorized, including an evaluation of growth potential, and requirement for tools, guidelines, services and types of adequate financing. Areas of potential innovation will be analysed and correlated to types of investment and growth barriers. Lessons learned will be discussed at Round Table meetings, and policy recommendations presented at a final public event. The partners in the consortium have been carefully selected to represent a broad spectrum of professional knowledge relevant to this particular sector. They provide a rich resource of contacts and networks in the medical devices field. They are knowledgeable about each other's core competencies and areas of excellence, through working on national projects and/or from the PAXIS and the Gate2Growth initiative.The partners, with geographic locations ranging from Scandinavia to Greece and from France to the Baltic, are skilled in delivering high impact, high response solutions based on in-depth knowledge of R&D activity and the challenging situations of many SMEs in the medical devices area. A full range of dissemination techniques, tested in many initiatives, both public and private, will be deployed to assure maximum awareness, use a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Cost effective, reliable and innovative stand alone photovoltaic system' to be submitted under Fourth Framework.

assistant: **Abstract**

PROJECT OBJECTIVES The CRISTAL-PV project objective is the development of a low cost and small complete PhotoVoltaic system. This system is dedicated to remote areas in Europe, to provide houses and small devices with a cheap yet reliable maintenance free PV system. In developing countries, this installation will provide a reliable low cost equipment. Since every part is designed for the application, a real warrantee will be considered. The CRISTAL-PV system aims at very low production cost (20% less than the present offer) implemented through an innovative design allowing reduction of the cost of all the parts of the installation, without sacrificing the reliability. The main R&D objectives are: - the development of innovative technical solutions concerning the PV generator, the charge control unit and the battery; - the optimisation of the overall performance of the complete system, by finding the best fit between the PV module and battery characteristics; - the standardisation of components and the preparation of moss production of PV systems, in order to achieve low costs. TECHNICAL APPROACH The CRISTAL-PV system will be composed of a 12V PV panel with an integrated regulator and a 12V/l00Ah new innovative maintenance free lead acid battery generation. The technical innovations are focused on the following aspects: - an energy storage battery able to be produced at low cost around 40 ECU per kWh) but this battery will be adapted to specific PV requirements: maintenance free, improvement of the cycling service life trio acid stratification), integrated protection against abusive discharges. - a low cost frameless solar module with simplified supporting devices having reduced number of modules thanks to higher efficiency. Furthermore, a new integrated regulation syste
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Thermally-Activated Delayed Fluorescence Nanoparticle Assemblies for Photodynamic Therapy' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

Photodynamic Therapy (PDT) is a non-invasive cancer treatment that uses light-activated, photosensitising dyes to generate highly reactive oxygen species (ROS) within a localised biological environment, leading to the destruction of cancer cells, while sparing surrounding healthy tissue. The PDT process comprises two stages: administration of a dye, followed by irradiation with light. Since ROS is only generated at the light-activated sites, tissue destruction is highly localised and side effects are significantly reduced. The potential for PDT is clear. However, for all this potential, widespread adoption has stagnated: only three dyes have been approved for cancer treatment globally, while the dye most commonly studied in clinical trials - Photofrin - is a statistical mixture of oligomeric porphyrins. Dye design for many years has focussed on porphyrins derived from Photofrin, and more recently phosphorescent ruthenium(II) polypyridyl complexes. However, in this proposal, a new design strategy is proposed: thermally-activated delayed fluorescence (TADF) dyes are the targets of interest. These are all-organic compounds that have small singlet-triplet energy gaps, which causes them to undergo rapid intersystem crossing and reverse intersystem crossing between the singlet and triplet states. By accessing the triplet state, they can readily generate singlet oxygen, which is one form of ROS, marking their potential for PDT. These compounds have been widely used organic device applications, but their uses in biological applications such as imaging and particularly PDT are much less. This proposal addresses this gap, using novel, cationic, near-IR emitting, TADF dyes. Their delivery to cells will be achieved using biocompatible, Extracellular Vesicles (EVs), which have been
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'NLR-proteins in Immunity and Inflammation' (2002-2006).

assistant: **Concept**

A growing number of acute and chronic inflammatory disorders including Crohn's and Inflammatory Bowels's disease have recently been linked to mutations in a new family of immune receptors, termed NLRs (Nucleotide Oligomerization Domain and Leucine Rich Rep eat containing Receptors) (Martinon, Trends Immunol 2005). NLRs recognize pathogens inside the cell and initiate, much like Toll like receptors, a series of signalling processes that stimulate and orchestrate the innate and adaptive immune responses.Despite their importance, the ligands, specificity and mechanisms of most NLRs are unknown. In order to identify their physiology and respective roles in human infections and inflammatory diseases, we will characterize the function of NLRs by biochemical and structural means. Functional analysis is the key to understanding the molecular mechanisms of disease and represents the new front-line and limiting factor for realizing potential benefits of genome-based science and stem cell research. Using an integrative and parallelized approach, Robert Schwarzenbacher and his colleagues contributed functional studies in the fields of immunity (EMBO J 1999), apoptosis (Cell 2000), enzymology (PNAS 2004), as well as drug discovery (Nat. Struct. Mol. Biol. 2004).Moreover, they recently unravelled the structure and function of the apoptotic protease activating factor 1 (Apaf-1) (Nature 2005), the first prototype of huge signalling platforms and a close relative of NLRs. Prof. Schwarzenbacher will bring his unique expertise in functional characterization and high throughput methodology gained at the Joint Centre for Structural Genomics back to Salzburg to create a new European centre of excellence. A primary goal of his team is to generate a platform for the development and application
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'NHM Researchers Night' to be submitted under Horizon 2020.

assistant: **Abstract**

Building on our experience in delivering successful European Researchers Nights, the NHM led partnership aims to deliver 12 inspirational events at 6 locations involving 6 partners (3 new to ERN).  The collaboration will deliver an extensive impact-rich awareness campaign, which over two years will  make over 10 million aware of ERN and its objectives. NHM and 5 subcontractors’ objectives beautifully align with ERN’s:•Increase awareness of the importance of research and innovation to society and our lives now and in the future •Directly engage public audiences with researchers, specifically targeting 18 – 35 yrs•Inspire school students to aspire to a career in science through engagement with researchers demonstrating the variety of exciting careers in science, targeting 11 – 18 yrs•Challenge the perceived stereotype of scientists and their work through awareness •Demonstrate the value of the EU and EU funding structures for collaborative research projects bringing benefit to society  •Demonstrate science is an integral part of our culture and heritage An inspirational schools programme, with direct engagement with scientists, targeting those students least likely to engage will open eyes to career opportunities in science. Events will entertain, astound and challenge the 18,000 attending, and will range from dialogue to didactic catering to learning preferences and motivations to attend. Each event will include an EU Corner with assured representation of Horizon 2020 Framework projects and MSCA researchers. Researchers’ will have clear messages to communicate to the audience. They will all receive remote training which will cater for the 500 plus researchers that will be involved in activities, 50 % of which will be female at NHM. In 2018 the museum hosts will connect w
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Female Flourishing and the Economic Frontier'.

assistant: **Innovation**

Women’s economic flourishing is not only an equity concern: growing evidence shows significant efficiency gains from women entering male-dominated fields and collaborating with male colleagues. However, there is little work on the process through which these gains towards the efficient frontier can be realized, and how the benefits can be shared by all. This proposal, comprised of 7 projects, will shed light on how to spur inter-gender collaboration and trust, through 3 distinct channels: 1) Interpersonal skills, 2) Community-based career paths and role models and 3) Institutional support and protection. On interpersonal skills, I will study the long-term effects of negotiation skills training on professional and educational outcomes for women in Zambia, as well as partner with the Italian Ministry of Education to research how these skills enable collaboration in middle school coding clubs. On community career paths, I will collaborate with the Zambian Ministries of Education and Health to investigate whether professionalized community health workers inspire girls in rural areas to pursue further education and enter male dominated fields. On institutional support, I will work with the Small Claims Court in Zambia to research whether contract-enforcing institutions spur collaboration between male and female entrepreneurs and improve business outcomes. This proposal makes four novel contributions to the literature. First, it focuses on how to resolve frictions in inter-gender collaboration beyond the household, to create economic gains while protecting the more vulnerable partner. Second, it exploits novel panel data and RCT interventions to study long-term impacts of empowerment interventions. Third, it looks at how interventions affect welfare outcomes and expand the ec
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Cross-species Transmission History and Evolution in the LIneage of Gammaretroviruses and related Endogenous Retroviruses'.

assistant: **Innovation**

Endogenous retroviruses (ERVs) are DNA fragments found dispersed in a wide range of genomes, from invertebrates to mammals, that resemble members of the Retroviridae viral family (termed here exogenous retroviruses or XRVs). Because XRV replication involves integration into the host chromosome, it is generally assumed that ERVs are the result of ancient XRV infections, which have passed into the germ-line of the host and expanded within it. ERVs are classified into three classes, while XRVs are classified into subfamilies and genera. Class-I ERVs and Gammaretroviruses are phylogenetically close. Therefore, Class-I ERVs are suggested to be the million-years archive of the Gammaretrovirus infections. I propose to study the viral and host factors that have affected the cross-species transmission history of Gammaretroviruses by studying the relationships between Gammaretroviruses and Class-I ERVs. I will use a bioinformatics’ approach to mine all the available mammalian genomes and extract all the Class-I ERVs. Then, I will build a phylogenetic tree containing all the available Gammaretroviruses and Class-I ERVs to clarify their relationships. I will use the tree to discriminate between shared invasions  and cross-species transmission (CST) events. I will implement statistical and phylogenetic methods to clarify if recombination or integrity of the env gene has enhanced or suppressed CST, respectively. I will also look at the protein receptors known to be used by some Gammaretroviruses and correlate their presence and phylogeny in the hosts with the CST events. Moreover, I will look the development of innate antiretroviral resistance mechanisms in the phylogeny of hosts and correlate this with the presence of Class-I ERVs or Gammaretroviruses. Finally, I will study the adap
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'AUTOMATED CODE INSPECTION FOR QUALITY IMPROVEMENT' (ACIQIM).

assistant: **Innovation**

Since the cost of repairing faults in software is considerably higher later in the development process, it is essential to obtain as small as possible fault tolerance throughout the complete development cycle. Denkart's objective is to reduce the workload by automating and streamlining the code inspection process. Our goal is to build an automated frame-work which can be used in any software development cycle.THE EXPERIMENTTo achieve the above mentioned objective, we will design and build an automated system which gives the biggest benefit, meaning reduced workload and smallest fault tolerance. During the baseline project we will concurrently do manual code reviews and run static and dynamic code analysis tools to determining the software quality factor. The results of the reviews and the resulting metrics will be combined to find a correlation. Out of this correlation report we will be able to make an automated selection of sources which have to be manually reviewed. By using the metric tools we will already exclude part of the faults while the automatic selection system will make sure the critical sources get reviewed. Though the framework must be applicable to any software development project we will use one of Denkart's typical legacy business application migration projects as baseline project.Denkart employs 35 people of which 7 will be involved in the ACIQIM PIE.EXPECTED IMPACT AND EXPERIENCEBy setting up the automated framework for code reviewing and selection Denkart will not only have build a mechanism useful for every development process, but we will also gain understanding in metrics (automatically and manually collected) and their relation towards software quality. Furthermore it will raise the quality issue to the level of developers and management which is
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Development of an in-vitro model of human blood-brain barrier for screening of CNS drug candidates' goes beyond current state-of-the-art under Fourth Framework.

assistant: **Innovation**

The blood-brain barrier, separating brain from blood, strictly controls the brain micro-environment, necessary for complex neuronal signalling. To assess the potential toxicity or bioavailability of new drugs in development, pharmaceutical companies would benefit from an in-vitro model of BBB, based on brain endothelial cells in culture. Today, only preliminary models have been described, derived from primary culture of non-human brain endothelial cells. Neurotech has produced recently several immortalized human brain endothelial cell lines, the phenotype of which will be fully characterized in-vitro. Using the most differentiated cell line, representative of brain endothelium, cell culture conditions on microporous filters will be optimized to allow minimal permeability to standard molecules and maximal transendothelial electrical resistance. Cerebrus will validate this in-vitro model using a wide range of drug development candidates for the treatment of various CNS disorders: potential toxicity to and permeability through endothelial cell monolayers will be assessed and the results will be compared with those obtained in animal studies. The availability of this in-vitro model of human blood-brain barrier will constitute a valuable alternative to the use of large numbers of animals in drug screening, will significantly accelerate the CNS-oriented drug discovery and development processes, and will ultimately decrease R&D costs.