RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'European Senior Watch Observatory and Inventory - A market study about the specific IST needs of older and disabled people to guide industry, RTD and policy' will create measurable scientific, societal and economic impact aligned with Fifth Framework.

assistant: **Impact**

The European society is ageing. SeniorWatch addresses the need to better understand and monitor market dynamics of IST applications targeted towards older citizens (including older disabled persons). It provides a unique European and global source of reliable empirical information on market potential. Information gathered through an innovative approach includes Europe-wide representative surveys (approx. 10,000 older citizens, and 500 decision makers from organisations providing home care. Based on country reports (all Member States, USA, Japan, Norway), and industry-lead technology analyses. Its synthesis will contribute to key European Union (EU) industrial and social policies. Dissemination will support industry, users, Fifth Framework Programme (FP5)/policies to rapidly develop and exploit this fast growing market segment. The experienced consortium brings together key centres of excellence to provide the complementary skills and perspectives needed, including experts from key European umbrella associations from industry and user groups.DESCRIPTION OF WORKWork starts with the refinement of a common framework to guide method selection, instrument development and results presentation. A unique approach integrates in an innovative manner empirical methods to establish a globally recognised observatory and key benchmarking resource for EU, industry, users and FP5 policy. First comes the design and execution of representative surveys of older and disabled people as well as of decision makers from organisations providing home care. Based on extensive experience from comparable surveys, the fieldwork will be commissioned from European market research organisations with an international reputation. In parallel, an Industry Expert Technology Watch Group starts its work by fo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'On-chip metasurface-based neuroimaging platform toward high-throughput drug screening in freely behaving animal' (FLAMMES).

assistant: **Concept**

A central goal of modern neuroscience is to correlate neurological conditions, external stimuli and behavior with the activity and location of individual neuron within a large brain volume. Thus, simultaneous recording of brain activity and organism behavior are fundamental to characterize circuit alterations underlying neurological disorders and to assess potential attenuation strategies. Thanks to the high degree of morphological, genetic and behavioral resemblance with humans, zebrafish is becoming a prominent model for studying neurological disorders and screening of neurospecific compounds. Owing to reduced light scattering, small size and 3R-principle compatibility of the zebrafish larvae, parallel whole-brain neuroimaging of multiple zebrafish might pave the way of in vivo drug discovery.  Recent studies report technological breakthroughs that enable monitoring of zebrafish whole brain activity with cellular resolution. Although widely used for functional imaging, larval zebrafish remains limited to manual, extremely challenging and low-throughput screening.Here, I propose to integrate my solid background in biophysics and micro-nano optics engineering with new skills I will build at the Host Institution and Secondment for the project success. Goal of this project is to enable optical whole-brain imaging of multiple zebrafish larvae (Danio Rerio) freely behaving. First, I will demonstrate zebrafish larva neuroimaging with a novel metasurface-based optical sectioning illumination (Aim 1). Second, I will demonstrate selective plane on-chip detection synchronized with the excitation plane (Aim 2). Finally, I will prove potential parallel larvae on-chip microscopy (Aim 3). The proposed neuroimaging concept is a flexible approach to perform high-throughput drug screen
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'O&M tools integrating accurate structural health in offshore energy' (WATEREYE) targeting Horizon 2020.

assistant: **Abstract**

Operation & Maintenance (O&M) costs are the main cost driver in offshore energy due to the difficult accessibility to the WTs, but also due to the environmental conditions. O&M costs can account for up to 30% of the levelised cost of energy (LCOE) and sensing & monitoring systems could help attain the expected fall to 70 EUR/MWh by 2030.The highest criticality (in €/kWh) in offshore wind is caused by structural failure, that mainly occurs due to corrosion processes non-adequately neither predicted nor monitored. For that reason, it is crucial to implement new monitoring, diagnosis, prognosis and control tools into the offshore wind farms (WFs) to enable Wind Farm Operators (WFOs) to take predictive smart O&M decisions fully considering structural components real and future status.WATEREYE aims to develop an integral solution that will allow to WFOs a 4% reduction of OPEX, accurately predicting the need for future maintenance strategy and increasing the offshore wind annual energy production. To this end, WATEREYE will:1/ develop a monitoring system capable of remotely estimating the corrosion level in exact WT locations (tower, splash-zone, tower-platform junction) as a supporting tool for predictive maintenance to considerably reduce the O&M costs and reduce the risk for operation failures; New Ultrasound corrosion sensors (ad-hoc, low-cost, high accuracy, fast-response, non-invasive) will be developed, as well as high efficient and robust wireless communications specifically conceived for offshore WTs hard communicating environment. Besides, a novel drone-based mobile platform to move one mobile sensor inside the WT tower will be developed.2/ develop enhanced prediction models by analysing the acquired data in novel ways (semantic models);3/ develop WT & WF control al
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Electricity generated from heat with nonlinear pyroelectric materials', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Electric energy stands for 20% of the total energy consumed in the world, and this share is expected to reach 40% by 2050 as an outcome of the need to decrease our dependence on non-renewable energies. Beyond sunlight and wind, heat is another formidable and poorly exploited source of electrical energy. Indeed, currently 72 % of the energy produced ends up in waste heat - and it has been predicted that up to 13 000 TWh could be recovered each year, which stands for Europe’s yearly total energy needs!In this context, my team recently showed that 40 grams of nonlinear pyroelectric ceramics can generate more than 10 Joules of electric energy from waste heat in one single thermodynamic cycle of 100 degrees. This is one order of magnitude larger than the closest state-of-the-art. We also demonstrated that these materials exhibit an energy efficiency of 40 % with respect to Carnot’s efficiency – which is beyond what photovoltaics and thermoelectrics can provide. Therefore, the scientific question of this project is the following: “Is it possible to generate Watts efficiently with this technology - and not only Joules?”Hence, the objective of this project is to show that energy harvesters made of nonlinear pyroelectric materials can generate 100 W of electric power from heat with 50 % energy efficiency. To do so, I will (1) design and fabricate environmentally friendly nonlinear pyroelectric harvesting modules, (2) analyse the fundamental role played by specific phase transitions on the heat-to-electricity thermodynamic conversion in such materials, (3) elaborate a power generator based on these harvesting modules with enhanced heat exchange capabilities able to generate 100 W of electricity from heat, and (4) prepare another specific heat-to-electricity generator showing that
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Turkic-Mongolian Language Contact: The Case of Kyrgyz'.

assistant: **Objectives**

Kyrgyz is a bridge language in terms of historical-comparative linguistics, the geographical territory of which is located between different groups of Turkic languages on the one side, and Turkic and Mongolian languages on the other. From the perspective of Turkic-Mongolian linguistic contacts, the Kyrgyz language is unique in that it has not only simple vocabulary transfers represented by lexical borrowings which in varying degrees can be seen in other Turkic languages, but it also shows influences from a Mongolian substrate. This substrate influence, usually defined with the terms “interference” or “imposition”, reveals itself not only in the phonological, morphological and syntactic levels of Kyrgyz but also in regional borrowings, something that is rarely the case in other Turkic languages. The question of the influence of Turkic-Mongolian language contacts on the formation of these two language groups has already been discussed in relevant linguistic and historical studies. However, the subject of borrowings and/or Mongolian-based contact-induced change in Kyrgyz has never been studied in detail, even though the existence of large-scale Mongolian influence on Kyrgyz vocabulary has sometimes been commented upon in certain studies. The project aims to determine the degree and depth of influence of the Mongolian languages on the formation of Kyrgyz owing to the age-long, intense linguistic contact among the Turkic- and Mongolian-speaking tribes that eventually formed the basis of Kyrgyz ethnicity. The project seeks to expand our knowledge about the nature, scope, and mechanisms of linguistic contacts in general and of Turkic and Mongolian languages in particular. These aims will be achieved by studying not only borrowings but also those features in Kyrgyz that appeare
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Assessment of soil carbon security using emerging techniques in hyperspectral imaging, X-ray florescence and pedometrics' in the context of a Seventh Framework call.

assistant: **Objectives**

Soil organic carbon is acknowledged as a biosphere sink within article 3.3 and 3.4 of the Kyoto Protocol Framework / Marrakech Accords, provided the sink can be maintained and demonstrated to be human induced.  Knowledge exists on the restorative land use and recommended management practices required to return carbon to depleted soils.   Soil carbon security needs to be addressed before soil carbon sequestration programmes can be advanced and deployed with confidence in schemes to ensure increase in national soil carbon stocks are secure. The scientific objective of this research is to understand the role of small-scale spatial organisation of soil organic carbon within topsoil with respect to the long-term security of the abiotic carbon store.  The project will use a combination of hyperspectral imaging, chemometrics, X-ray fluorescence technology and pedometrics to build a new scientific understanding of soil carbon security.  The training objectives of this research are to develop an advanced understanding of multivariate statistical techniques, developed at the University of Sydney, for spectroscopic analysis, pedotransfer and geospatial analysis that are necessary for data analysis.  It is envisaged that this research work will transfer knowledge of pedometrics to the UCD Bioresources Research Centre, which is a centre of excellence in soil hyperspectral imaging at University College Dublin and will provide a protocol for the assessment of soil carbon security that will have potential for improving national scale carbon reporting and have potential for spin-out for commercial development.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Molecular mechanisms of synapse formation and physiology' to be submitted under Seventh Framework.

assistant: **Abstract**

The present study aims to elucidate how bidirectional signaling systems regulate synapse formation and activity, in vivo. In particular, I will address how repulsive actions of Eph/ephrin signaling during axon pathfinding are overcome and turned into adhesive actions, required for synapse formation and functioning. Therefore, I will study the effects of either stimulation or inhibition of Eph receptor clustering in two different in vivo models and, in an inducible way. Live-imaging of Eph receptors in the zebrafish retinotectal system will enable study of their localization and trafficking, as well as the effect of clustering modulations on the ensuing cellular response. Four different aspects of retinotectal system formation will be evaluated, including topographic mapping and arborization of retinoganglion cells as well as synapse formation and stability. Furthermore, an EphA4 knock-in mouse will be generated to study the effect of clustering during synaptic transmission and on synapse stability in the hippocampus. Therefore morphological, electrophysiological and functional approaches will be used. A final part of this project aims to find downstream signaling effectors that are specifically recruited or activated by lower- or higher order Eph receptor clusters.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Sex-specific and multi-generational effects  of an optimized diet' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

It is a well-accepted concept that organisms aren’t shaped by their genes alone, but respond variedly to different environments. In recent years it has become evident that these responses to environments are in fact heritable and can be transmitted across generations. In rapidly changing environments this may have important consequences for the ability of populations to adapt and avoid extinction. To date, we know very little about the role of non-genetic mechanisms on adaptation and evolutionary processes, a gap that needs to be filled if we want to be able to understand and predict how climate change is going to affect natural populations. Here, I will harness an emerging framework for the study of dietary ecology, in which diets that maximise components of reproduction and longevity can be created, based on the amino acid content of the translated exome (i.e., the DNA sequence of the coding portions of genes) of an organism. This so-called “exome-matched” diet will help to resolve outstanding questions in the rapidly developing field of non-genetic inheritance, principally by uncovering the role of non-genetic effects in evolutionary adaptation. In addition, sex-specific effects may serve to prepare offspring for environmental conditions in a sex-specific way, but despite fundamentally different reproductive strategies the interacting roles of parental and offspring sex is so far under explored.  The project builds upon my expertise with social and diet-induced effects and expands my skills into the fields of optimal nutrition and sexual conflict. Using cutting edge experimental and genomic approaches in collaboration with a major Spanish Research Centre and one of Australia’s top Universities, this project will yield high impact results in evolutionary biology, and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'z-Movi cell screening and sorting platform' under Horizon 2020.

assistant: **Concept**

Cell immunotherapy is a breakthrough treatment that uses immune cells to directly attack tumours. It is considered the mostexciting development in cancer treatment in years. When it works, patients with life-threatening cancers live far longer ormay even be cured. But so far, immunotherapy only works for few types of cancer and few patients, and finding the mosteffective immune cells is still an immense challenge.LUMICKS is developing z-Movi, the first high-throughput platform that screens and sorts immune cells based on theirfunctionality using non-invasive techniques. z-Movi is a unique and powerful solution that now allows researchers to look atthousands of immune cells and find the right ones within a couple of minutes – a process that would take months withstandard technologies. Therefore, z-Movi is the perfect R&D tool to help and speed up the process of bringing newimmunotherapy treatments to market. z-Movi is expected to disrupt the immunotherapy market, which is mostly driven byinnovation and is expected to reach €100B by 2021.LUMICKS started by teaming-up with immunotherapy leaders such as the Dutch Cancer Institute and Institut Pasteur todevelop z-Movi. The first developed z-Movi was already introduced to early adopters. After completing optimisation, a newgeneration z-Movi will target the immunology research institutes, biotech and pharma markets. Users from those segmentshave already demonstrated concrete interest in our solution, or are in the process of acquisition. The incremental z-Movirevenue stream from this EIC Accelerator project will be around €20M by 2022 and the net profit margin will double.LUMICKS’ post-EIC ultimate goal is to go beyond the


**Keywords:** high-throughput, Screening & sorting, Cancer therapy, Microfluidics, Image analysis
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'FREEWAY : safely and effortless commute in an urban environment' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

It is not a bike, it is not a scooter, it is a lot better, it’s FREEWAY: a new revolutionary means of transportation allowing to safely and effortlessly commute in an urban environment. Protected by a worldwide patent, FREEWAY is a small and clean scooter, on three wheels. FREEWAY is unique since it is very light, 14kg, with 2 front wheels for stability and safety, a back wheel that includes the electric engine, and it is fitted with latest generation batteries. FREEWAY may be folded and unfolded within seconds. When folded, it can be carried along, on its two front wheels like a suitcase. Therefore, FREEWAY may be kept with you at all times and is perfectly suitable for intermodal mobility. FREEWAY is an hybrid type of bike with no equivalent product on the market; nevertheless, its market is already very broad. The most direct competition of FREEWAY comes from electric bikes, with a good market growth rate that should be 9.1% over the 2013-2020 period, to reach a market of 1,9 million in Europe.The main objective of FREEWAY business innovation project is the transfer of a new innovative and competitive solution seizing European transport sector opportunities with the view of providing profitability and growth. The specific objectives will be to provide technological and economic viability of FREEWAY electro mobility concept in order to develop a market strategy ensuring Europe wide market uptake, support growth and self-sufficiency at mid-term and participate to Europe bike industry leadership.In addition, FREEWAY business innovation project will address urban environmental and mobility defies by offering the market with an innovative electric powered vehicle which is more light, more practicable, more safe and secure and more trendy for the users, thus, improving use
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fifth Framework proposal for the project 'Linking hydrographic frontal activity to ecosystem dynamics in the north sea and skagerrak: importance to fish stock recruitment'.

assistant: **Objectives**

OBJECTIVES AND EXPECTED ACHIEVEMENTSOne of the main objectives of the Common fisheries policy as agreed at the intermediate Ministerial Meeting in Bergen in 1997 and subsequently formulated by the General directorate for fisheries (in: The Common Fisheries Policy", Section 8. 1) is to consider environmental issues and interactions between fisheries and the ecosystem in fisheries management decisions.This so called ecosystem approach is based on - the identification of processes in, and influence on, the ecosystems which are critical in maintaining their characteristic structure and functioning, productivity and biological diversity- taking into account the interaction among food-webs of the ecosystem- protecting the chemical, physical and biological environment necessary to the well-being of these ecosystems.The commission highlights the role of research in this context and states that as a first step the knowledge of the ecosystem as a whole will be increased."