RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Cooling, AGN Feedback and Evolution in Groups'.

assistant: **Innovation**

This proposal aims to facilitate close collaboration between researchers in the UK, Italy, USA and India to study the nature and consequences of the energy transferred from supermassive black holes at the centres of galaxies to the surrounding intergalactic medium (IGM) in groups of galaxies. The research combines data from opposite ends of the electromagnetic spectrum: low-frequency radio observations track the history of outbursts from the black holes, while X-ray data allow us to determine their effects on the ten-million-Kelvin gas of the IGM. The partner institutions have long records of internationally-recognised research in these areas. The University of Birmingham is one of the top few teams worldwide in the study of groups with a solid track record in X-ray astronomy (particularly using ESA's XMM-Newton X-ray observatory), while the  INAF-Istituto di Radioastronomia provide access to some of Europe's best experts in the low-frequency radio regime. The Smithsonian Astrophysical Observatory (US) is the home of NASA's Chandra X-ray observatory, and has a strong claim as the preeminent X-ray astronomy institution worldwide, while the National Centre for Radio Astrophysics (India) operates the Giant Meterwave Radio Telescope (GMRT), the first and currently the only radio observatory to achieve high spatial resolution and sensitivity at low frequencies. The collaboration will bring together experts with diverse skills to study closely one of the outstanding puzzles of modern astrophysics, providing direct benefits to the European institutions involved, the wider scientific community, and to the European Research Area as a whole, through increased scientific returns from current European facilities, increased access to international resources, and the scientific and t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'All-inorganic nano-rod based thin-film solarcells on glass'.

assistant: **Innovation**

Thin film solar cells, based on non-toxic, abundant and air-stable silicon (Si) will probably, based on forecasts, dominate the photovoltaic market in the future and thus replace bulk Si from its leading position. This prognosis is fostered by the strong cost reduction potential due to highly effective materials utilization at low energy consumption. However, thin film Si suffers from inherently small grains, which limits efficiencies to ~10% due to carrier recombination at grain boundaries. A radical innovation of the Si thin film materials synthesis route is needed to circumvent this problem. ROD_SOL aims at the synthesis of Si nano-rods, densely packed at sufficiently large diameters (few 100 nm's) and lengths (>1µm for sufficient carrier absorption in indirect semiconductors) directly on cheap substrates like glass or flexible metal foils. The idea is to grow Si nano-rods from the gas phase that are inherently defect free, with a wrapped around pn-junction that bares the potential to decouple absorption of light from charge transport by allowing lateral diffusion of minority carriers to the pn-junction, which is at most a few hundred nm away, rather than a few µm as in conventional thin film solar cells. That way, efficiencies as in bulk Si are expectable, however, with the advantage that the 'nano-rod carpet' layer, is at most a few µm thick. A 'nano-rod carpet' that thin shows a strongly increased optical absorption. Thus, the 'nano-rod carpet' is not only the active solar cell element but at the same time its own light trapping structure. For synthesis of the nano-rods, development of suitable contact materials and characterization of physical and structural properties four experienced research institutes have joined forces. Despite the fundamental materials rese
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Distinguishing genetic overlap and causal relationship among attention deficit-hyperactivity disorder and substance use disorders' (ATTENTIVE), addressing dissemination and exploitation.

assistant: **Impact**

The ATTENTIVE project will deliver a comprehensive training-through-research to a talented postdoctoral fellow in two leading multi-disciplinary research groups. I will bring clinical, molecular biology and genetic skills and I will receive extensive training in state-of-the-art genomic data science and cell biology, creating a two-way transfer. The proposed work will expand my experience, research competencies and professional networks, leading to the possibility to become an independent researcher. The research part of the proposal is focused on understanding the biological basis of the comorbidity observed between Attention Deficit-Hyperactivity Disorder (ADHD) and Substance Use Disorders (SUDs), as it is unclear which the underlying mechanisms are. Using large-scale genome-wide association study (GWAS) datasets , we will test whether this epidemiological and genetic correlation is due to shared risk alleles acting independently on both disorders or to causal effects between the disorders. We will combine different analytical methods, leveraging genome-wide data and brain-specific information related to additional omics domains. We will derive information regarding transcriptomic and epigenomic changes in brain tissues and cells. GWASs can identify a large number of genetic variants with potential disease association, but functional analysis remains a challenge. Therefore, we will validate the results through induced pluripotent stem cells (iPSCs) to study cellular pathophysiology. The iPSCs carrying the variants significant from the GWAS will be differentiated to neural cells and neural mRNA will be analyzed by RNA-Seq. The expected results will provide novel information regarding the molecular mechanisms at the basis of this pathogenic association, also providing i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'New Concept of Metal-Air Battery for Automotive Application based on Advanced Nanomaterials' under Seventh Framework.

assistant: **Concept**

The aim of NECOBAUT Project is to develop a new concept of battery for automotive based on a new metal/air technology that overcomes the energy density limitation of the Li-ion battery used at present for Electrical Vehicles. Some metal/air cells were developed in the past, but did not give the demanded requirements for commercial use. Two decades of improvements in materials for electrodes, electrolytes and batteries and mainly in nanomaterials have helped for developing a battery that should fulfil the requirements of the car industry. The technology that is developed in the project addresses mainly the design and manufacturing of both electrodes of the battery: the negative electrode composed by the selected metal, and the air cathode with the catalyst supported on a carbonaceous material. Air is necessary for running the battery and allows having a very light battery, which is essential for the automotive industry. Another important advantage is the low cost of the materials used for manufacturing the battery: the selected metal, carbon support electrode and potassium hydroxide as electrolyte. All these materials are recyclable.The consortium is composed of 8 partners (3 IND, 2 Universities and 3 RTD) covering the complete value chain: battery manufacturer, nanomaterials development (i.e.; nanocatalys, additives and support materials such us carbon), modelling and simulation for cells and batteries design, scaling-up, safety and risks studies for batteries.A proof-of-concept metal/air cell is manufactured and tested in the project. In addition, the battery concept is validated for automotive application. Although the main market for the battery developed by NECOBAUT is the car industry, it could be also used for stationary electricity storage (photovoltaic and wind
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Exotic bees and introduced plants: The role of pollinator limitation in the establishment and spread of alien weed species' (POLLIM), addressing dissemination and exploitation.

assistant: **Impact**

The introduction of non-native organisms to new ecosystems is one of the most pressing environmental problems of the present time. Despite many costly attempts to control alien weeds, new introductions still pose a significant threat to many regions; a problem exacerbated by climate change and increased human travel.In order to successfully control introduced plants, biologists need to understand more fully ways in which they are able to spread into new areas. One aspect of weed biology that is poorly understood is their interaction with pollinators, in particular non-native insects such as bees. This project aims to determine whether pollination by European honey- and bumblebees aids the spread of invasive weeds in one of the worst affected regions, Australia.Many plant introductions in Australia do not yet pose a significant problem. However, the plan to introduce bumblebees to mainland Australia could precipitate the spread of so-called 'sleeper weeds', plants whose populations may be limited by the lack of effective pollinators. In this project I will examine weed populations in mainland Australia and Tasmania, where bumblebees are already present, to compare the reproductive success of weeds with and without their main pollinators.I will also develop a model based on current Tasmanian bumblebee distributions and habitat use, to predict bumblebee spread should they be introduced onto the mainland. Using a novel combination of state-of-the-art molecular and GIS techniques, the project will provide excellent training that will aid the career development of the applicant, and increase the skill base within the EUÂ's scientific community.In addition to forging collaborative links between two of the leading Universities in Australia and the EU, the project will provide i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'The world’s most sensitive absorption microscope' to be submitted under Horizon Europe.

assistant: **Abstract**

QlibriNANO is the worlds most sensitive absorption microscope (1,000 times more sensitive than state-of-the-art), enabling the detection, imaging, characterization, understanding and development of nanoscale matter on a new level by its unique combination of fast and ultrasensitive hyperspectral imaging. QlibriNANO gives access to a so-far inaccessible area of information relevant for research fields like nanoparticles, optical coatings, thin films, among others, making the invisible visible for the first time. Our innovation rests on the usage of an optical microresonator instead of a conventional objective. We have untapped this possibility, since Qlibri has developed a breakthrough fabrication method of micromirrors based on a semiconductor quantum cascade laser system. This proprietary method has allowed Qlibri to become the first company in the world to commercialize micromirrors, a key component for our first-of-its-kind resonator microscope. Qlibris unique blend of expertise, combining a profound know-how in microresonators and deep understanding of microscopy, particularly raster scanning techniques, has made it possible to make a technology transfer from Quantum optics to optical microscopy to develop QlibriNANO. The great market potential of our disruptive resonator microscope has been confirmed by more than 20 prospective customers. This EIC Transition project has the objective of validating the product-market fit for the nanotechnology and optical coatings markets, improving the technical requirements (mostly fast spectroscopy) of our system as well as the usability, and validating these technological improvements with end users in these sectors (TRL 6). Moreover, we aim to improve the manufacturability of QlibriNANO, and ensure a cost-efficient, scalable an
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Fast Molecular WOCs' (2007-2013) under Seventh Framework.

assistant: **Objectives**

This proposal focuses on a cutting-edge approach to the development of the next generation of molecular water oxidation catalysts (WOCs). Artificial water splitting is as an essential technology because it allows for the conversion of abundant solar energy and H2O to the carbon-neutral fuels O2 and H2. However, artificial water splitting technologies have been impeded by slow WOCs. To date, an unsystematic approach to designing WOCs has been taken. No attention has been directed towards how the intrinsic properties of the catalyst, such as oxidation state, spin state, d-electron count, and ligand field affect the catalytic activity. Additionally, the factors that affect O-O bond formation, the most demanding step in water oxidation catalysis, are poorly understood. Our key goals are to utilise a first principles, bottom-up approach to water oxidation catalyst design to develop the next generation of fast molecular WOCs. Specifically, we propose:1) To develop a family of ML complexes (M = Mn, Fe, Co, Ru) utilising ligands (L) that enforce octahedral, trigonal bipyramidal, and tetrahedral ligand fields; 2) To apply the family of ML complexes as WOCs in order to gauge how oxidation state, spin state, d-electron count, and ligand field, affect the catalytic activity; 3) To carry out detailed mechanistic investigations into O-O bond formation using the ML complexes.The CIG grant will play a major role for the applicant in his transition from an early career researcher to an independent, established European scientist with a higher research profile.The CIG will be the principle source of funding for lab supplies, equipment and travel for the researcher's new group, and salary for the applicant, and two young researchers. The CIG will allow the applicant to more quickly attrac
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Acces aux installations de neutrons du laboratoire Leon Brillouin' to be submitted under Fourth Framework.

assistant: **Abstract**

The Laboratoire Leon Brillouin (LLB), french laboratory, carries out fundamental research in the field of condensed matter using 24 spectrometers installed on the neutron beams of the reactor Orphie. LLB proposes to put at the disposal of European Community researchers 10% of its total experiment time (which is typically 4600 days per year). Orphie is a modern reactor, equipped to produce altogether thermal, 'cold' and 'hot' neutrons. So, european researchers, in particular those coming from countries which do not have a reactor, find at LLB very performant equipments: diffractometers for structure determination on powders or single crystals, diffuse and small angle scattering, reflectometers, and spectrometers for inelastic scattering study of dynamics and excitations. LLB is an excellent place for training of young researchers, because they meet many colleagues of various origins, and also because the management of beam time allows deeper reflexion and more discussions. This opening of LLB to european researchers, which requires a large effort of its scientific staff, will be very beneficial in terms of increased scientific collaboration. Apart from the travel and subsistence fees, a financial contribution of the European Community to the corresponding running costs, is essential for a correct operation of the project.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Systems Biology of T-cell Activation in Health and Disease', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

T-cell activation, whether induced by pathogens or auto-antigens, is a complex process relying on multiple layers of tightly controlled intracellular signalling modules that form an intricate network. Defects in this network can cause severe and chronic disorders such as autoimmune diseases. Although 5% of the population suffer from these diseases, only a few therapeutic treatments are available. To a large extent this is attributed to the lack of systems-level insights, which would provide concepts of how to modulate T-cell activation. The SYBILLA project groups 14 partners from 9 different EU countries, including 3 SMEs. Through a multidisciplinary effort it aims to understand at the systems’ level, how T-cells discriminate foreign from auto-antigens. Towards this goal, a transgenic mouse system will be used as a tractable physiological model. Data will be validated in human T-cells and a humanised mouse model for multiple sclerosis. SYBILLA will develop technological and mathematical tools to generate and integrate high-density quantitative data describing T-cell activation. Proteomics, transcriptomics, metabolomics, imaging and multiplexed biochemical techniques will be applied to obtain holistic maps of T-cell signalling networks and to achieve a quantitative understanding of the network and its regulation in response to different inputs. Building upon our existing network model, constant iterations will be used to develop more robust dynamic models to describe the network’s response to perturbations. This will culminate in the generation of a Virtual T-Cell, allowing computer simulation to refine the predictability of physiological and pathophysiological reactions.  SYBILLA’s impact on EU biopharmaceutical competitiveness will be enormous through identification of
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Identification and therapeutic targeting of common arrhythmia trigger mechanisms' (EUTRIGTREAT).

assistant: **Concept**

Arrhythmias are common manifestations of heart disease which frequently cause sudden cardiac death (SCD) or other devastating health problems. In Europe, prevention of SCD by device and drug therapy is expensive and increasingly strains public health resources due to a growing population at risk. However, identification of patients at increased risk for SCD is ineffective, and SCD prevention strategies are not directed at the underlying risk mechanisms. To address this challenging situation, new insights into genetic and environmental modulators of SCD risk, arrhythmia initiating mechanisms (Triggers) and therapeutic strategies (Treatments) are urgently needed. The EUTrigTreat consortium proposes a translational project strategy based on interactive objectives (modules). Module 1 investigates novel genetic arrhythmia mechanisms in patients and is supported by Module 2 which investigates genetic and environmental SCD risk modulators in animals with arrhythmias. Module 3 elucidates common environmental arrhythmia risk mediators including obesity and diabetes. Module 4 applies molecular and biophysical imaging techniques to identify novel risk biomarkers. Module 5 translates experimental data through computer modeling and prediction analysis. Modules 6 develops new SCD risk identification strategies through combined patient and experimental studies. Module 7 develops and validates novel therapeutic drug compounds and a new form of anti-arrhythmic device therapy. The pre-clinical and clinical activities will potentially result in patents of diagnostic and therapeutic applications, licensing strategies, early clinical trials and a spin-off company. Module 8 manages, advises and reviews the project progress of EUTrigTreat. Ultimately, we aim to better understand and educate a