RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Early-Stage Organocatalysis' (ESO) targeting Horizon Europe.

assistant: **Abstract**

Organocatalysis has drastically advanced stereoselective chemical synthesis. From an underdeveloped niche area, it has become the most frequently applied approach to asymmetric synthesis. Organocatalysis is also developing into a technology, which can be used to make pharmaceuticals, scents, and other fine chemicals. However, the early stages of industrial chemistry, the upgrading of hydrocarbon-based alkenes, arenes, and alkanes, are still largely dominated by heterogeneous and transition metal catalysts. Here we will address the question if a selective, Early-Stage Organocatalysis (ESO) can be developed that directly delivers high-value substances from abundantly available hydrocarbon feedstock chemicals, while significantly saving energy and other resources. During the last few years, we have developed confined organic acids as a new catalyst class that features enzyme and zeolite-inspired active sites with well-defined pockets for selective substrate recognition and catalysis. These catalysts offer a widely tunable reactivity range, reaching extreme levels with turnover numbers exceeding 106 in challenging asymmetric carbon-carbon bond forming reactions, and approaching “magic acid” reactivity toward the activation of olefins. We now aim to take confined acid catalysis to another level by designing new, even more reactive acids that enable the utilization and valorization of steam-cracker-based hydrocarbons in selective organocatalysis. Specifically, we propose three aims: (1) Developing asymmetric olefin hydrofunctionalizations including hydrations and hydroarylations; (2) An early stage functionalization of simple arenes such as benzene and toluene via highly stereoselective and regioselective electrophilic aromatic substitution reactions; and, as the ultimate tes
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Investigation and Monitoring of Time-varying Environments on Macro and Nano Scales' (2014-2020), addressing dissemination and exploitation.

assistant: **Impact**

The ultimate goal of my research is to develop novel approaches to detect dynamical changes in cluttered time-dependent electromagnetic environments. Theoretical and experimental methods will be applied on a range of highly important problems, including radar tracking and optical imaging of complex processes on micro and nano scales. Nowadays demands, set by increasing complexity of systems under study, challenges applicability of existent solutions, opening a room of opportunities for multidisciplinary rewarding research. Scalability of Maxell’s equations with respect to frequency and classical-quantum correspondence principles suggest developing a broad range of dynamical phenomena by applying multidisciplinary concepts, as my team has recently demonstrated. Radio detection of macroscopic objects (e.g. airborne targets) and optical imaging of conformational changes in colloids (e.g. bio-chemical activities), being representative examples on a very diverse size scales, share similar underlining physics and engineering principles for their analysis. This multidisciplinary research considers the phenomena on macro, micro and nano scales, utilizing classical and quantum properties of electromagnetic radiation and light for achieving superior performances in detection beyond existing capabilities. Radio detection will be performed via mapping internal mechanical properties of a target, enabling attributing a unique signature in a clutter. The novel concept of ‘swimming antennas’, driven by holographic optical tweezers, will be developed for optical mapping of micro and nano scale motion. Slow decaying luminescent tags, conjugated with antennas, will allow monitoring a motion beyond the diffraction limit by considering quantum properties of light. Fundamental study and expl
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Algorithms, Security and Complexity for Quantum Computers' (ASC-Q), addressing dissemination and exploitation.

assistant: **Impact**

As progress is made in implementing quantum computers, the question is looming: What will we do with them?This proposal is concerned with the theoretical computer science aspects of this question. Part of this question is concerned with quantum algorithms (WP1). We know of several examples of quantum algorithms with large speedups over the best known classical algorithms, such as Shor's poly-time integer factorization algorithm. While this is evidence that quantum computers will be useful once built, it does not tell us what quantum computers will be used for in practice (probably not much factoring). To ensure that quantum computer users are best able to make use of them, we will focus on developing general techniques for the design of quantum algorithms that can be easily applied by subject-matter experts in different fields to the problems that interest them.We will also consider the constraints of early quantum computers in our algorithm design. First, we would like to understand how the limited memory of early quantum computers will impact what they can do. Some of the most important techniques for designing quantum algorithms are already well-suited to the study of space-bounded computation, and we will generalize and improve these in WP1. To complement this, we will study lower bounds and complexity (WP2), focusing on space-bounded complexity classes, which have many relationships with other complexity classes. Second, since most early users will have to delegate their quantum computations, we would like to understand which quantum algorithms can still be used in various delegated or multiparty settings where some type of security is a consideration. We take the novel approach of using a quantum algorithmic model called span programs to design secure quantum comp
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Removal of Legacy Substances from polyvinylchloride (PVC) via a continuous and sustainable extrusion process'.

assistant: **Innovation**

REMADYL aims at recycling so-called ‘old PVC’, i.e. PVC additivated with hazardous legacy substances (LS) such as low molecular weight phthalate plasticisers (mainly DEHP) and heavy metal based stabilisers (mainly lead). This ‘old PVC’ constitutes most of current hard (e.g. window frames, tubes) and soft (e.g. flooring or cables) PVC post-consumer waste. The presence of LS is a persistent barrier for PVC recycling as there are currently no economically viable solutions for their removal.To tackle this major challenge, REMADYL will develop a breakthrough single step continuous process based on extractive extrusion technology in combination with novel solvents and melt filtration, which has the potential of rejuvenating ‘old PVC’ into REACH compliant high purity PVC tuned towards the demands of various soft and hard PVC products at market competitive cost (ca €570/ton, CAPEX and OPEX included). The process also has potential for other plastics applications, e.g. removal of (halogenated) flame retardants.Using this process, REMADYL will demonstrate the circular use of PVC for window profiles and waterproofing sheets, providing a flagship example for the circular economy. The extracted phthalate plasticizers will be safely disposed (with energy valorisation) and the lead will be re-used in batteries.REMADYL will deliver a breakthrough support to the Circular Economy Package and resource efficiency targets for Europe as recovered PVC will reduce incineration and landfilling. Assuming we recycle 400kton/year of ‘old PVC’ waste within 5 years after REMADYL, this will result in a reduction of ca 800ktons CO2eq and 8ktons lead emissions. This also implies the creation of ca 800 new jobs and a turnover of ca €280million. Safety aspects will be studied, leading to best practices,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'A fresh perspective on the diversity-stability hypothesis: Linking functional composition and population performance to inform assessments of coral reef community resilience' under Horizon Europe.

assistant: **Concept**

Thought to possess a greater trait redundancy across species, more biodiverse systems are considered better able to maintain their stability following disturbances. However, despite ranking amongst the planets most biodiverse ecoregions, tropical rainforests and coral reefs are highly vulnerable to ongoing global change. Meanwhile, the localised arrangement of species assemblages impacts the relative resilience of systems with comparable diversity, such that similar systems exhibit differing responses to the same disturbances. Consequently, predicting the viability of natural systems and implementing effective conservation action, requires a more nuanced understanding of how the local configuration of species traits mediates the effects of diversity on population-, community- and ecosystem-level stability. Through the proposed research project, ReefCoRe, I will evaluate how the spatial arrangement of functional diversity within ecological communities refines population resilience and, therefore, mediates ecosystem stability. I will firstly utilise comparative modelling approaches to explore how the spatial context of trait diversity influences the survival, growth, and recruitment of individuals across the tree of life. Next, I will scale-up these assessments to evaluate how coexistence between functional groups impacts upon measures of population performance and resilience. Finally, I will develop tools aimed at uniting measures of demographic performance and resilience with more established measures of coral reef health, providing a platform for continued research linking the dynamics of coral populations with the wider functioning of their reef environments. By distilling the association between the functional composition of natural communities and measures of popula
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Chromosomes on shuffle:  disentangling the relative contributions of natural selection, sexual selection, and drift on the evolution of a chromosomal inversion.' (2014-2020), addressing dissemination and exploitation.

assistant: **Impact**

Comprehending adaptation is key to understanding our changing world. Despite this, we still know little about the genetic basis of adaptation. The picture becomes even more complex when we move beyond base pairs to large structural variation. Inversions may contain hundreds or thousands of loci but segregate largely as one unit, as they prevent recombination. Nonetheless, these giant genomic units seemingly facilitate rapid adaptation and speciation in a wide variety of taxa. The key objective of this project is to determine how inversions contribute to adaptation and how they evolve by systematically examining and disentangling the forces that govern the evolution of an inversion in a model species, the seaweed fly Coelopa frigida. I will combine interdisciplinary techniques to address crucial and novel aspects of the relationship between inversions and adaptation. I will be based at the Linnaeus Centre for Marine Evolutionary Biology (CeMEB), an interdisciplinary centre of research excellence at the University of Gothenburg (UGOT) in Sweden. Via training-through-research including a secondment to the Instituto Gulbenkian de Ciência in Portugal I will learn new techniques from multiple disciplines, including advanced scripting for analysis of next generation sequencing data, theoretical modelling, and reduced representation library preparation and analysis.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Large-Scale Electrosynthesis of Borylated Azines' to be submitted under Horizon Europe.

assistant: **Abstract**

'The Nobel prize-winning Suzuki-Miyaura cross-coupling involves the palladium-catalysedcoupling of a borylated molecule with an aryl halide and is the 2nd most used process by thepharmaceutical sector.Azines are small-molecules integral to discover and manufacture pharmaceuticals andagrochemicals. Using azines in Suzuki-Miyaura cross-coupling reactions represents the idealsolution to introduce these important motifs in discovery molecules but here is where theproblems come:1. There is currently very limited way of borylating azines.2. Borylated azines, especially the ones containing a boron vicinal to the N-atom, arehighly unstable.We urgently need chemical methods delivering borylated azines in a fast and cost-effectivemanner and that can then be employed in Suzuki-Miyaura cross-coupling reactions.As part of our ERC-2018-StG NEBULAR, focused on the development of novel photochemicalstrategies in radical chemistry, we recently identified a strategy that generates boryl radicalsand provides far greater capability over any other method to both prepare and utilizeborylated azines in modular fragment synthesis.B-ELECTRO aims to make the synthesis of our borylated azines workable on large scale andthus attractive to pharma and agro industries.This program provides a unique opportunity for the commercialization of our borylatedmaterials and their utilization by end-users, thus providing innovative chemistry solutions andlong-lasting impact to pharmaceutical and agrochemical industry and eventually our society.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fifth Framework proposal on 'Continuity properties in the structure of the enumeration degrees.'.

assistant: **Concept**

To prove continuity results in the enumeration degrees analogous to results in the Turing degrees , and then to answer the long open problem of determining at which point the theory of the local structure of the enumeration degrees becomes undecidable.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Automated super-resolution polarimetric nonlinear microscope 'PolarNon'' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

The analysis of materials is a key requirement for device quality control in medical, electronic and photonic industry. Currently, fluorescence imaging, electron microscopy and photoluminescence are typical tools for quality control in research and industry. However, they suffer from several limitations: complex samples preparation, special environments, destructive and time-consuming measurements. The development of new materials and components needs innovative approaches for fast and non-destructive testing (NDT). We propose to use nonlinear optical responses that are strongly dependent on material properties like crystal structure, defects and roughness for NDT. Despite the high potential of nonlinear optics in material sciences, the existing solutions are not convenient in terms of equipment, measurements methods, sample preparation and human resources costs.We propose the implementation and testing of a fully automated polarimetric nonlinear microscope ‘PolarNon’ as a hardware and software solution for NDT and quality control of materials or optoelectronic components in the semiconductor industry (Market segment I), and metallic or ceramic alloys in the aerospace industry (Market segment II). The PolarNon system overcomes the limitations of current methods: it does not require special sample preparation or measurement conditions, like low temperatures, vacuum or ultrathin substrates, and it can characterize materials already incorporated in a device. The PolarNon includes a method of per-pixel analysis of optical images to reconstruct the material crystalline properties down to the pixel resolution. We already successfully applied this approach to several materials for predicting samples inner structure. This project allows us to build an industrial prototype for f
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Anthropological Materialism: a Neglected European Tradition' (AMEUR).

assistant: **Concept**

The purpose of the project “Anthropological Materialism: a Neglected European Tradition” (AMEUR) is, from the perspective of Walter Benjamin, to circumscribe “anthropological materialism” as a neglected part of European identity, from the 19th to the 21th century. The task is double. On the one hand, it is to build the concept of “anthropological materialism” as a world vision that, explicitly and implicitly, theoretically and concretely, in French and in German cultures, played an essential role in Europe during the 19th Century. On the other hand, the task is to actualize the concept of “anthropological materialism” for political sociology, philosophical anthropology and modern history, i.e., in a multidisciplinary manner, in order to understand Europe in the 20th and 21th centuries. The candidate will work on the manuscripts in the Benjamin Archives, on the sources of German anthropological materialism, and he will compare them to the French counterparts. He will write a synthetic presentation, with representative extracts, from French sources and German sources, in order to present the theoretical movement of anthropological materialism as a European movement in the 19th Century, its influence on the social and political movements in Europe in the 19th century, and its actualization on Europe in the 20th and in the 21th century. The project looks at a hidden tradition of Europe since the origin of its modernity. It opens up a new perspective on Europe, elevating the tradition of anthropological materialism to the level of a methodological paradigm in order to reveal the obscure mechanisms of the construction of Europe. It gives new insights into the others “materialisms”. It also produces relevant knowledge about the construction of European tradition. The quality o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'An investigation of the mechanism of action of growth hormone secretagogues for improving body composition and quality of life in the aged' to be submitted under Fifth Framework.

assistant: **Abstract**

The age-related decline in endocrine function plays an important role in many of the changes in body composition and brain function that form part of the aging process. We propose to carry out studies in animals investigating how synthetic growth hormone secretagogues (GHS) act to improve body composition and brain function. Electrophysiological and neuroanatomical studies will determine how GHS interact with the brain pathways controlling growth hormone secretion, appetite and metabolism. Chronic GHS exposure will result in a new equilibrium of endocrine and CNS activity - we will study the consequences of long-term GHS exposure on hypothalamic gene expression and body composition. Studies of GHS action in animals with deletions in specific genes will identify the key sites of action of these compounds. Studies in obese diabetic animals (i.e. with symptoms of syndrome X) will include effects of GHS agonists and antagonists on the progression of the disease. Finally, since GHS increase circulating levels of insulin-like growth factors, we will determine the effects of GHS in the central IGF system, that has a protective role against neurodegeneration