RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Genetic Networks: Emergence and complexity' goes beyond current state-of-the-art under Sixth Framework.

assistant: **Innovation**

To understand the properties of complex systems, we currently lack a theoretical framework for the analysis of aggregate behaviour in multi-scale, multi-objective systems. GENNETEC gathers a consortium of computer scientists, physicists, biologists and bioinformaticists. It takes inspiration from a biological case (transcriptional interaction networks) that exemplifies many challenges in complex systems research, including elemental heterogeneity, interconnected scales in time and space, emergence of higher level behaviour, and hierarchies.GENNETEC will exploit its case study to build a theoretical framework for modelling/simulating complex systems and for the analysis of their emergent properties. This development will make use of methods from formal software engineering and from qualitative approaches in statistical physics. It will deal with the two-way information flow between two or more successive levels of model description, with particular attention on consequences for aggregate behaviour. To tackle complex systems with more modelling levels, hierarchies of descriptions will be studied.Winthin this theoretical framework we will develop bottom-up multi-scale methodologies to analyse global aggregation behaviours. Design of multi-stable systems will be handled using multi-objective optimization algorithms, borrowing from evolutionary computation and from message-passing techniques. These studies will be extended and generalized across other, non-biological applications to understand and design complex systems with desired aggregate behaviour, having both stability and versatility / adaptativity.The biological outcome of these studies will be transferred into a scalable sofware tool to achieve a breakthrough in the bioinformatics domain of inference in transcriptio
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Performance Untapped Modulation for Power and Heat via Energy Accumulation Technologies'.

assistant: **Objectives**

Natural gas fired Combined Cycle (CC) power plants are currently the backbone of EU electrical grid, providing most of regulation services necessary to increase the share of non-programmable renewable sources into the electrical grid. As a consequence, Original Equipment Manufacturers (OEMs) and Utilities are investigating new strategies and technologies for power flexibility. On the other hand, existing cogenerative CCs are usually constrained by thermal user demand, hence can provide limited services to the grid. At the same time, CHP plants are highly promoted for their high rate of energy efficiency (> 90%) and combined with district heating network are a pillar of the EU energy strategy.To un-tap such unexploited reserve of flexibility, and to further enhance turn-down ratio and power ramp capabilities of power oriented CCs, this project proposes the demonstration of an innovative concept based on the coupling of a fast-cycling highly efficient heat pump (HP) with CCs. The integrated system features thermal storage and advanced control concept for smart scheduling. The HP will include an innovative expander to increase the overall efficiency of the HP. In such an integrated concept, the following advantages are obtained: - the HP is controlled to modulate power in order to cope with the CC primary reserve market constraints;- the high temperature heat can be exploited in the district heating network, when available; low temperature cooling power can be used for gas turbine inlet cooling or for steam condenser cooling, thus reducing the water consumption;- in both options, the original CC operational envelope is significantly expanded and additional power flexibility is achieved.In general, the CC integration with a HP and a cold/hot thermal storage brings to a redu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Design, Synthesis and Characterization of ‘Responsive’ MR Contrast Agents Sensitive to Glutamate' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

Functional Magnetic Resonance Imaging (fMRI) based on Blood-Oxygen-Level-Dependent (BOLD) contrast is currently the mainstay of neuroimaging, whose ever growing applications provide a wealth of information regarding the human brain. The chief advantage of BOLD-fMRI is its non-invasive nature and excellent coverage, but it is limited by poor temporal and spatial resolution, and its surrogate nature. In fact, BOLD imaging, as well as other fMRI methods, are insufficient for a detailed study of the neural networks that underly human or animal cognition. We propose to develop a new approach. The aim is to study exogenous MR contrast agents that are ‘responsive’ biochemical functional markers, capable of detecting neuronal activity in real time and translating it into changes of MR contrast. Our objective is to develop glutamate responsive contrast agents to image changes in different parts of the brain upon neural activation. We also aim to improve the sensitivity of these bio-responsive agents by introducing additional modality for Positron Emission Tomography (PET) in the molecules. Initially, novel selective classes of specific, efficacious and optimized Glutamate receptors antagonists along with contrast enhancing macrocyclic lanthanide-chelates, will be developed. The initiatives in chemistry include both tailored organic synthesis and complexation of non-toxic metallo-pharmaceuticals, whose ligand design is dictated by the desired structure-activity relationship. Glutamate receptor sensitive specific extracellular responsive contrast agents will be considered. Every agent will be characterized by different chemical methods and finally evaluated by means of in vitro MR/PET measurements in simulated physiological conditions.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Transport of Reaction Intermediates in the Stepwise Assembly of Fatty Acids' under Horizon Europe.

assistant: **Concept**

Fatty acids are essential metabolites used in biological cell wall formation, energy storage, and signal transduction. Fatty acid synthesis is carried out in an iterative sequence of reactions, conserved across all species. Yet different organisms have developed different solutions, the most impressive is the fungal fatty acid synthase (FAS). The 2.6 MDa molecular complex integrates all enzymatic functions required for the stepwise assembly of fatty acids. Its architecture is reminiscent of a chemical nanofactory: The enzymatic domains face the lumen of the barrel-shaped complex, where nascent fatty acids are transferred between active sites by an integral acyl carrier protein (ACP). The function of the fungal FAS has long been in focus of research, not only due to its elaborate architecture but also because it is ideally suited as a platform for synthetic biology. Fatty acid derivatives are ideal precursors to produce biofuels or fine chemicals; and fungi are well adapted for industrial applications.Advances in experimental structural biology have established a framework for the progression of the synthesis cycle. However, the driving element is the transport of reaction intermediates by the ACP which is inherently dynamics. Thus, structures alone are insufficient for a mechanistic understanding of the fungal FAS function. TRISAFA aims to close this knowledge gap by integrating advances in structural biology with molecular dynamics simulations to resolve the pace and regulation of the transport process in atomistic detail. This approach will address three hitherto unanswered questions: First, how are the transport dynamics coupled to the conformational dynamics of the FAS? Second, how is the pace of the transport regulated? And finally, what factors determine terminati
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Development of bio-impregnated lime for agriculture practice, agro-lime improvement with beneficial, nitrogen-fixing bacteria' (1998-2002) under Fifth Framework.

assistant: **Objectives**

The object is: development of a new lime-based soil-activator and bio-fertilizer by lime-treatment with selected beneficial, nitrogen-fixing bacteria in specialised units. The offered product and process can locally adapt, helping the general usage to improve the fertility of soils. The limited factors of this development were biological and economic problems. The biological problems can be overstepped by using wide range of specially selected tolerant strains of bacteria. The economic problems can exceed by developing locally adaptable treating process, and multiplication methods by using the targeted Demo Units. The targeted Units can set up at SME lime producers or distributors for low cost production. The expected result is: the multiplication of bacterial bio-fertilizer usage; the improvement of beneficial effects of the used lime; reducing chemical fertilization in farming systems and decreasing the fertilizer-based environment hazards; improvement of soil fertility and plant health.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'The Evolution and Development of Complex Morphologies' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Plant and animal organs display a remarkable diversity of shapes.  A major challenge in developmental and evolutionary biology is to understand how this diversity of forms is generated.  Recent advances in imaging, computational modelling and genomics now make it possible to address this challenge effectively for the first time.  Leaf development is a particularly tractable system because of its accessibility to imaging and preservation of connectivity during growth.  Leaves also display remarkable diversity in shape and form, with perhaps the most complex form being the pitcher-shaped (epiascidiate) leaves of carnivorous plants.  This form has evolved four times independently, raising the question of whether its seeming complexity may have arisen through simple modulations in underlying morphogenetic mechanisms.  To test this hypothesis, I aim to develop a model system for carnivorous plants based on Utricularia gibba (humped bladderwort), which has the advantage of having one of the smallest genomes known in plants (~2/3 the size of the Arabidopsis genome) and small transparent pitcher-shaped leaves amenable to imaging.  I will use this system to define the morphogenetic events underlying the formation of pitcher-shaped leaves and their molecular genetic control.  I will also develop and apply computational modelling to explore hypotheses that may account for the development of U. gibba bladders and further test these hypotheses experimentally.  In addition, I will investigate the relationship between U. gibba bladder development and species with simpler leaf shapes, such as Arabidopsis, or species where the epiascidiate form has evolved independently.  Taken together, these studies should show how developmental rules elucidated in current model systems might be exten
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Active Learning with Large Language Models for Cross-lingual Pseudo-labeling in Computational Social Science'.

assistant: **Objectives**

Large Language Models (LLMs) have become ubiquitous in the area of Natural Language Processing (NLP).   This project aims to advance the applications of LLMs in the multidisciplinary field of Computational Social Science (CSS). Specifically, LLMs are often used to pseud-label (at scale) variables in data that are of interest to social scientists (e.g., a psychologist would look for emotion markers, an economist for statements about money, a human rights researcher for toxic language etc.) I will develop and test novel tooling for applying LLMs to efficiently pseudo-label CSS data in a cross-lingual setting.  The project will proceed in three phases. First, a dataset and methodology for evaluating the language robustness of LLMs (isolated from all other confounding factors) will be developed. Second, using this methodology a set of general best practices will be determined for the scenario of applying LLMs to cross-lingual pseudo-labeling for CSS. Finally, both existing and novel active learning approaches will be investigated to minimize the manual annotation effort required to oversee the pseudo-labeling process. Using insights from this project a user-friendly freely publicly available tool for pseudo-labeling using LLMs will be published. The methods will be tested on two example tasks: toxicity detection and disinformation detection. Overall, the project results will make the work of CSS researchers more efficient in terms of both time and financial resources. Moreover, the cross-lingual nature of the tool will make it applicable to languages other than English, including small and low-resourced languages. Consequently, this project will contribute to make tooling accessible to a wide and diverse set of CSS researchers, increasing the outreach and inclusivity of CSS
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'COGNitive Industries for smart MANufacturing (COGNIMAN)' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

Glass fibre production, precision machining of large parts (e.g. wind turbines), additive manufacturing of medical implants and high-temperature metal production are manufacturing examples with processes that are difficult to automate. The main reasons for the actual labour intensive efforts in these scenarios are lack of full understanding and control over the individual manufacturing steps and the high complexity of the tasks. This has severe impacts on sustainable growth, manufacturing productivity, efficiency and flexibility due to the large amount of unpredictive waste in production and processing time. COGNIMAN is devoted to improving these situations by developing and demonstrating a novel concept of ?digital cognitive smart manufacturing? that will shift the future design of manufacturing processes towards autonomous and predictive manufacturing with improved flexibility, safety and efficiency. This initiative will provide the means to facilitate flexible, resilient, reconfigurable, safe, sustainable, and efficient smart manufacturing by integrating key technologies. They include simulations, digital twins, advanced sensors, machine learning toolbox and cognitive robotics integrated in human-centric modular toolboxes that can be easily adapted to substitute varying manual manufacturing processes. By tackling significant challCOGNIMAN will provide the means to facilitate flexible, resilient, reconfigurable, safe, sustainable, and efficient smart manufacturing by integrating simulation, models, digital twins, sensors, Artificial Intelligence (Machine Learning), data processing and analytics, robotics, and autonomous systems in a human-centric modular toolbox that can be easily adapted to new manufacturing processes and environments with the ultimate objective of b
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Cognitive Radio Oriented Wireless Networks' (CROWN), addressing dissemination and exploitation.

assistant: **Impact**

Europe is in the midst of a communications revolution facilitated, in part, by advances in wireless communications, such as wireless internet and leading to the next generation of systems. Both power and spectrally efficient techniques are major design objectives for next generation wireless networks. Recent studies have indicated that many licensed frequency bands remain unused 90% of the time. In order to address this inefficiency, spectrum regulatory authorities have introduced a secondary market initiative to better utilize the licensed spectrum by removing the regulatory barriers. This introduces the concept of dynamic spectrum licensing rendered possible by a set of techniques branded in short as Cognitive Radio" (CR). While appealing as a theoretical concept, CR still faces a number of serious challenges that prevent it from wide commercial adoption. The main core challenges that we plan to tackle are 1) the problem of distributed interference awareness and 2) the problem of communicating over as many as possible concurrent channels in the same communication spectrum with minimal mutual interference, enabled by smart antenna systems. These have been major showstoppers for CR, resulting in a low confidence that such unlicensed systems can indeed operate in a transparent way avoiding interference with each other as well as licensed systems. We plan to address these problems by a combination of distributed intelligence (via a powerful MAC protocol) and advanced signal processing, including intelligent interference detection and smart antenna processing, tailored to the network architecture at hand. In order to validate the developed techniques, we will 1) derive (information theoretic) benchmarks for the maximum spectrum efficiency bounds and 2) develop an experimen
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'New trends or old habits? Stability and changes of political styles since 1960' in the context of a Horizon Europe call.

assistant: **Objectives**

Hardly a week goes by without reports of elected officials – often pictured as ‘populists’ – having used vitriolic language and attacked the personal traits of their opponents. In a context of ‘restyling of politics’, the style of political actors is presented as increasingly emotive, personalised, and confrontational. In the absence of systematic comparative study, such claims remain however trivial intuitions and anecdotes that are as old as politics. This raises critical questions: are modern political styles new trends or old habits? What are the institutional and political factors that constrain or favour the rise of certain styles?The POLSTYLE project provides a groundbreaking empirical and theoretical contribution by analysing the evolutions of political styles in four European democracies since 1960. It posits that configurational evolutions shape the stability and changes of political styles over time: it depends upon the varying responses of the types of actors, arenas and political systems vis-à-vis abrupt exogenous shocks and endogenous incremental changes.For these empirical and theoretical goals, the project builds a unique dataset of actors’ political styles performing in various arenas (TV, print press, parliaments, and Twitter). Different indicators will trace evolutions of political styles in terms of contents, nature of interactions and forms of expressions. Finally, the project develops a theory that explains how and why patterns of styles unfold according to configurational evolutions. Overall, the POLSTYLE project decisively contribute to ongoing theoretical debates about the nature of political representation in modern democracies, and how democratic linkages with voters are built on a daily basis. While some scholars and political observers sugge