RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Infant Responses to Maternal Carrying in Human as Early Biomarker and Prognosis Estimator of Child Psychopathology: a Study on Autism Spectrum Disorders and Perinatal Brain Disorders in Early Infancy' in the context of a Seventh Framework call.

assistant: **Objectives**

In this project we aim to understand the psycho-physiological aspects of mother-infant interaction and their paramount influence on typical and atypical development. Mother-infant bonding is the earliest and most critical social relationship of mammalian infants. To promote this bond, infants have innate behaviors to seek maternal proximity and protest upon separation via communication with the mother vocally and through body movement. However, the physiological mechanisms regulating these infant behaviors remain largely undefined. As a model to study very early mother infant interaction we study the maternal and filial contribution during maternal carrying. In a pioneering study (Esposito et al., 2013) we have shown in rodent pups and human infants a specific calming response to maternal carrying. This calming response is a coordinated set of central, motor, and cardiac regulations and is a conserved component of mammalian mother-infant interactions. During the proposed project we aim to test the hypothesis that: (i) the calming response to maternal carrying influence the efficiency of mother-infant interaction; (iia) very early malfunctioning of the infant contribution to maternal carrying may be an early biomarker of child psychopathology (i.e. Autism Spectrum Disorders, ASDs) and (iib) may provide an opportunity for an early estimation of prognosis in infants with Perinatal Brain Disorders (PBDs, i.e. Cerebral Palsy). The study will use physiological and behavioral assessment of infants with typical and atypical development. The present study provides immediate implications for general parenting practices and might provide a tool for the evaluation of the autonomic functions and sensory integrations of neurological disorders in early infancy. Finally, these results
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Piloting cascaded continuous flow synthesis for the pharmaceutical industry' (PICASCO) under Horizon 2020.

assistant: **Objectives**

PICASCO aims to deliver the commercial proof of concept of a novel endto-end flow manufacturing and a novel corresponding compact flow miniplant. This is performed through the first continuous 4-step solvent-freeflow manufacturing of a pharmaceutically relevant API compound at anindustrial scale. Currently applied batch manufacturing techniques leavemuch room for improved quality, efficiency, cost-effectiveness andenvironmental friendliness. Flow multi-step manufacturing can address allthese issues simultaneously, but to date has not been brought to anindustrially useful scale. PICASCO sets out to scale this final barrier.


**Keywords:** Continuous flow synthesis
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Multi-scale analysis of the interplay between cell morphology and cell-cell signaling' (MorphoNotch).

assistant: **Innovation**

Signaling, genetic regulatory circuits, and tissue morphology are inherently coupled to each other during embryonic development. Although changes in cellular and tissue morphology are commonly treated as a downstream consequence of cell fate decision processes, there are multiple examples where morphological changes occur concurrently with the differentiation processes. This suggests that a feedback between cell morphology and regulatory processes can play an important role in coordinating tissue development. Currently, however, we lack the experimental, theoretical, and conceptual tools to understand this interplay between cell morphology, signaling, and regulatory circuits. In particular, we need to understand (1) how intercellular signaling depends on the cellular morphology and on the properties of the boundary between cells, and (2) how intercellular signaling, genetic circuits, and cell morphology integrate to generate robust differentiation patterns. Here, I propose to combine quantitative in-vitro and in-vivo experiments with mathematical modeling to address these questions in the context of Notch signaling and Notch mediated patterning, typically used for coordinating differentiation between neighboring cells during development. We will utilize novel reporters and micropatterning technology to analyze Notch signaling between pairs of cells. We will elucidate how the geometry and the molecular composition of the boundary between cells affect signaling. At the tissue level, we will study how the interplay between cell morphology and Notch signaling gives rise to robust patterning in the mammalian inner ear. We will use cochlear inner ear explant imaging to track the transition from disordered undifferentiated state to ordered pattern of hair and supporting cells
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Denmark and Russia: Why two Arctic empires developed so differently and continue to diverge?”'.

assistant: **Innovation**

At a time when public attention is focused on differences rather than similarities, comparative studies of Russia and Europe open new perspectives beyond the familiar dichotomous discourse. In this spirit, my MCSA project “Denmark and Russia: Why two Arctic empires developed so differently and continue to diverge?” (DEAR) examines Russo-Danish relations in the 18th and the 19th centuries. For the entire 18th century the two states were very close in terms of economic and institutional development, but after the abolition of serfdom in Denmark in 1800 their paths diverged significantly. This was most striking with the gradual collapse of the Danish empire, and the subsequent rapid development of the remaining territory, whereas Russia remains relatively “backward”, but with its territory largely intact. From the 1860s until the 1920s a much-reduced Denmark became a teacher to its larger partner through the transfer of knowledge, expertise, and experts – a process which aided Russian development, and emphasizes the links between the two countries.  The overarching question motivating DEAR is to explore what accounts for the ultimately divergent pathways of the two empires as well as the rapid disintegration of the Danish Empire and the survival of the Russian Empire, given their initial similarities. DEAR combines the expertise of the Historical Economics and Development Group (HEDG) at the University of Southern Denmark (SDU) in Danish economic history and quantitative methods, my research experience in Russian economic history, and the access of both to unique datasets on the preindustrial and early industrial development of these countries.


**Keywords:** Russian economic history, inequality, Danish Empire, comparative studies
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fifth Framework proposal on 'Advanced three-dimensional two-phase flow simulation tool for application to reactor safety'.

assistant: **Innovation**

The objective of the project is to provide the scientific and technical basis for a new generation of Thermal-Hydraulic (TH) codes aimed at substantially improved prediction capabilities for safety relevant phenomena in present or future innovative Light Water Reactors (LWR). This includes in particular the further development and adaptation of state-of-t he- art numerical techniques for transient two-phase flows allowing a high resolution of complex multi-dimensional flow processes. Specific attention will be given to the incorporation of advanced modelling strategies such as the multi-field representation of two-phase flow, t he transport of interfacial area concentration and handling of turbulent diffusion terms.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'GIESEPP MP - Gridded Ion Engine Standardized Electric Propulsion Platform - Medium Power Solution' in the context of a Horizon 2020 call.

assistant: **Objectives**

The consortium proposes to continue the activity started under COMPET-3-2016-a to develop, build and test to TRL6/7 the first European Plug and Play Gridded Ion Engine Standardised Electric Propul-sion Platform (GIESEPP) to operate ArianeGroup ion engines with option of alternative thrusters, for a medium power application.The consortium’s intention will be •to reach a TRL6/7 of the medium power system with at least partial qualification to allow flight readiness•to improve European competiveness in this field by    + optimising industrialisation both on thruster unit and EPS level   + increasing the GIE systems production capacities   + significantly reducing the recurring costs•and to maintain and secure the European non-dependence on this crucial technological field.The project will significantly advance design and development of this standardised electric propulsion platform for GEO (and MEO) applications:- In order to cope with challenging mission scenarios, dual mode functionality of the thrusters will be realised. This ensures that the beneficial high ISP characteristics of Gridded Ion Engines are maintained, whilst also offering a competitive higher thrust mode- Activities will be covered not only by the competence of expersts in their respective fields but also by the use of advanced Engineering Models (EM), respectively Qualification Models (EQM)- The GIESEPP systems will not be limited to xenon as an operating medium; assessment will be performed to ensure functionality with alternative propellants- The proposal will describe the roadmap to higher TRL beyond 2023/2024, providing a cost competitive EPS that will meet the highest standards for an industrialised, rapid production process- The anticipated business case is targeted for long term exploitation up to
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fifth Framework proposal on 'Bringing research advances in neurobiology to society (BRAINS)'.

assistant: **Concept**

Neck Institute with 148 researchers & 51 PhD students is the largest biological research centre in Poland. Research is mainly focused on neurobiology in interdisciplinary approach from molecular to organism level. It covers problems in brain physiology from petrochemical mechanisms to principles of integration of neuronal networks and foundations of animal and human behaviour. Due to high quality of research and strong international links Neck is recognised as a leader in neuroscience.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'BEES IN EUROPE AND THE DECLINE OF HONEYBEE COLONIES' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

The BEE DOC comprises a network of eleven partners from honeybee pathology, chemistry, genetics and apicultural extension aiming to improve colony helath of honeybees. The BEE DOC will empirically and experimentally fill knowledge gaps in honey bee pest and diseases, including the 'colony collapse disorder' and quantify the impact of ineractions between parasites, pathogens and pesticides on honey bee mortality. Specifically BEE DOC will show for two model parasites (Nosema and Varroa mites), three model viruses (Deformed Wing Virus, Black Queen Cell Virus, Israel Acute Paralysis Virus) and two model pestcides (fipronil, τ-fluvalinate) how interactions affect individual bees and colonies in different European areas. The BEE DOC will use transcriptome anayses to explore host-pathogen-pesticide interaction and identify novel genes for disease resistance. The BEE DOC will specifically address sublethal and chronic exposure to pesticides and screen how apicultural practices affect colony health. The BEE DOC will develop novel diagnostic screening methods and develop sustainable concepts for disease prevention using novel treatments and selection tools for resitant stock. The BEE DOC will be linked to various national and international ongoing European, North-, and Latin-American colony health monitoring and research programs, which will not only ensure a pan European but also a global visibility and the transfer of results to a world wide community of beekeepers.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Time-Resolved Electron Spectroscopy of a Challenging Highly Innovative Collective Excitation Study' (TRES-CHIC-ESt), addressing dissemination and exploitation.

assistant: **Impact**

Plasmons are collective modes of the solid-state electrons representing a characteristic elementary excitation in solids. In theory plasmons are simplified as quasi particles with a well-defined energy and momentum from the instant of their creation to their decay. The dynamics of plasmons and the concomitant liberation of solid-state electrons is not yet fully understood. It is the aim of the present project to unveil the dynamics of this complex many-body process with unprecedented temporal resolution. The fundamentals of plasmonics are at the core of this project, as well as technologies involving secondary and hot electrons. Albeit challenging, the above scientific vision of the applicant is not only innovative, but it is timely and relevant to various scientific and technological fields ranging from space technology, to photovoltaics and semiconductor industry, as well as life sciences and biology. With the advent of modern time-resolved experiments, the objective of the experienced researcher (ER) outlined above has realistically come within reach. The TRES-CHIC-ESt project will be carried out at a host institution which is a pioneer in the field of attophysics under a supervision offering optimal conditions for young researchers to widen their scientific horizon and to boost their careers, thus offering to the applicant the ideal environment to pursue her innermost desire: to become a world-class successful researcher. In exchange, the solid-state Physics background of the ER will enrich the perspectives of the hosting group, who among others will benefit from her prior experiences and collaborations. During her PhD-studies, as a MSCA ITN fellow, the ER has already studied the causal relationship between plasmons and secondary electrons using spectroscopy with co
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'SKILL BILL: Skill to Boost Innovation and professional fulfiLLment in a sustainable economy' (2021-2027) targeting Horizon Europe.

assistant: **Abstract**

SKILLBILL’s overall objective is to develop a large and strong foundation for the growth and acceleration of renewable energy’s deployment, thanks to engaging with stakeholders of the whole chain, diffusing scientific culture and skilling multi-level workers.The basic idea underling the project is that the knowledge should be diffused at several different levels and qualitatively appropriate both to train the adequate number of workers and to increase RES awareness and to reach a more social and inclusive EuropeThe project aims at creating several pathways to induce target groups to get interested or involved in RES besides their initial level of education and their working position: the technological RES potential can be reached by increasing hard and soft skills of potential users and stakeholders, developing interest in the topic and having clear and appropriate approaches, such as tools and learning modules using suitable language. It’s important, beside the creation of instruments for the upskilling and reskilling of workers, technician and designers, to have awareness modules for unspecific public in order to fight against ignorance, fake news, gender gap and the phenomenon of functional illiteracy: it is widely documented that lifelong suitable learning process is the fundamental driver to support the development, maintenance and update of skills. SKILLBILL proposes concrete actions to accelerate the deployment of  renewable energy at different levels:1.Stakeholder community engagement 2.Knowledge sharing and peer learning3.Skilling, upskilling, reskillingSKILLBILL will i) analyse and involve all the interested parts in open discussion using adequate language; ii) create several different pathways to increase skills after having mapped knowledge gap and without g
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Adaptive  plasticity as a key for invasion success in disturbed ecosystems', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Invasive species are a major constituent of global change, threaten local biodiversity, ecosystem services, and cause serious economic damage. Invasion science has tried to discern the factors that determine whether a non-native population will become invasive or not.  Invasive populations are usually depleted in genetic diversity, creating the so-called 'invasion paradox' because traditional perspectives consider high genetic variation to be crucial for rapid adaptation to novel environments. Recent theoretical advances trying to solve this paradox propose that contemporary pre-adaptation to human-altered habitats within the native range or during the transport stage in the introduction can promote invasions. If this is true, introduced populations will exhibit increased adaptive tolerance to a stressor associated with transport, e.g. eutrophication, contributing to their success in the recipient environment. The aim of this project is to understand adaptive mechanisms that promote invasion success in widespread invasive freshwater vertebrate and invertebrate species. I will study the phenotypic differentiation of wild populations of the eastern mosquitofish in an eutrophication gradient, complemented with laboratory ecotoxicology experiments, both in the native (Florida) and invasive (Spain) ranges of the model species. This intraspecific comparison will be supported by the interspecific study of 3 sympatric freshwater amphipod species in Germany to assess potential competitive shifts in the invasive ones stemming from higher tolerances to eutrophication. Including natural populations with such particularly well described invasion histories will show why some populations become invaders and others do not. Current developments in molecular genetics , e.g. ‘-omics’, giv
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Conference for Advanced Inquiry in the Interactive Arts - Science, Technology and Art Research (CAiiA-STAR)', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

CAiiA-STAR 2000 aims to bring together advanced researchers in the fields of science, technology and multimedia art to explore the effects of the new multimedia and networking technologies on consciousness. Existing work undertaken by the CAiiA-STAR Research Centre has demonstrated the ability of young researchers to adapt to the field of consciousness, and work seamlessly between previously separate disciplines. It is anticipated that the development of Information and Communication Technologies will be significantly enhanced by the work of the conference. Innovation and Creativity in state of the art European science will be encouraged by the multidisciplinary nature of the conference.The conference will include exploration of the fields of artificial intelligence, immersive virtual reality environments, robotics, and cognitive science. The use of advanced multimedia techniques on the internet, and the impact of cyberspace on the average citizen will also be explored. The conference aims to provide a unique opportunity for a diverse range of scientific and artistic fields to collaborate. This collaboration will inform the consciousness debate, and enable development of key strategies and awareness of theoretical and practical problems in the development of new multimedia technologies, which are otherwise ignored. The conference will advance European science through the consciousness debate, from which delegates will return to their respective disciplines with an enhanced view of the impact of their work, and potential outlets for scientific research which otherwise might not have been realised.ftp://ftp.cordis.lu/pub/improving/docs/HPCF-2000-00094-1.pdf