RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Development and characterisation of new semi-conducting polymers soluble in environmental-friendly solvents for self-assembled nanostructures and application in advanced electronic devices' (BIOPOLTRONIC) under Sixth Framework.

assistant: **Objectives**

Recent developments of chemical and biological sensors require semi-conducting (conjugated) polymers preferably processible from environmental-friendly solvents like alcohols and with an affinity towards the physiological medium of the analyte (water). The objective of the project is to develop at IMEC, through transfer of knowledge, competences and know-how in the synthesis of ionic conjugated polymers (ICPs): amphiphilic and polyelectrolytes. ICPs feature ionic or polar side groups, which render the mater ials soluble in water and/or alcohols, and possess an intrinsic tendency to organize into supramolecular architectures in solution and in solid state, which make them promising candidates as a platform for the development of chemo- and biosensors. The new semi-conducting polymers will be designed in order to achieve a control of the nanoscale morphology and will be based on poly(p-phenylene vinylene) derivatives (PPVs) substituted with ionic or polar side chains.They will be synthesised using the precursor sulphinyl route" developed at IMEC for the synthesis of "classical" PPVs. Monomer synthesis and polymerisation methods will be developed and optimised for environmental-friendly solvents. These new materials will be evaluated in various device structures as Light Emitting Devices (PLED), organic transistors, organic photovoltaics and in chemical and biological sensors. This will result in a thorough characterisation of the electrical properties of the ICPs under study. To reach that goal two types of exper tises will be required over two years: 36 person-months of organic and polymer chemists preferably with a background in conjugated polyelectrolytes and/or amphiphilic polymers, and 18 person-months of an electronic engineer or material physicist with aback ground
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'A Computational Distributed System to Support \nthe Treatment of Patients with Major Depression' in the context of a Seventh Framework call.

assistant: **Objectives**

Depression is one of the most common causes of short and long term disability in Europe. It accounts for substantial costs both directly to health services and indirectly through lost productivity and the burden of caring. Most patients with Major Depression (MD) recover with treatment, which may be with antidepressant drugs, psychological therapy or, in severe cases, hospitalisation. However for many, that recovery is either slow or incomplete. Research shows that psychological therapies can be delivered effectively without face to face contact: computerised cognitive behavioural therapy (CCBT) is suitable for self-guided treatment in the individual's own home. However, its value for patients is limited by the difficulty of staying engaged, and there are professional concerns that important changes in mood may be missed. Help4Mood proposes to significantly advance the state-of-the-art in computerized support for people with MD by monitoring mood, thoughts, physical activity and voice characteristics, prompting adherence to CCBT, and promoting behaviours in response to monitored inputs. These advances will be delivered through a Virtual Agent (VA) which can interact with the patient through a combination of enriched prompts, dialogue, body movements and facial expressions. Monitoring will combine existing (movement sensor, psychological ratings) and novel (voice analysis) technologies, as inputs to a pattern recognition based decision support system for treatment management. The advances in Help4Mood will provide a closed loop approach to treatment support for MD patients. Outputs include: a validated personal monitoring system; a personal interaction system embodied in a VA and a clinical decision support module. By identifying and supporting patients with delayed reco
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Policies for Smart Specialisation'.

assistant: **Objectives**

Smart Specialisation is a successful innovation policy concept which has become a cornerstone of the European cohesion policy and also addresses several of the Sustainable Development Goals. However, the early implementation of SmartSpec policies has raised concerns among scholars and policy makers, who have pointed to a number of gaps in its conceptualisation, design and implementation. POLISS (“Policies for Smart Specialisation”) will tackle these gaps with the aim of making the design, implementation and evaluation of Smart Spec policies more effective in Europe. POLISS is a joint collaboration of 8 leading European academic institutions and 14 partners spanning local governments, development agencies, international organizations, research institutes and private companies. POLISS brings together a diverse set of actors from all the fields contributing to SmartSpec; therefore it adopts a multidisciplinary approach by integrating their insights and knowledge. Building on their expertise and everyday engagement with SmartSpec policies, POLISS aims at: a) providing new systematic evidence and methodological tools to scholars, policy makers and local practitioners for designing and assessing SmartSpec actions in EU regions and beyond; b) building a PhD programme where a new generation of experts in regional development and innovation policy will be trained and once graduated will be possibly employed in regional, national and European private or public organisations that work on regional development and innovation; c) providing a forum for coordinating the vast community of researchers and practitioners working on local development and innovation, which is often sparse and fragmented.


**Keywords:** regional development, European cohesion policy, innovation policy, entre
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'MobIle Laboratory Capacity for the Rapid Assessment of CBRN Threats Located within and outside the EU'.

assistant: **Concept**

Background: In case of major intentional, accidental or natural CBRN incident, fast in field identification of agents is crucial for optimal risk assessment, risk management, and counter measures. A determining factor is to bring a rapidly CRBN deployable diagnostic and forensic capacity as close as possible to the crisis area.Objective: To harmonize the definition of a CBRN mobile laboratory and to identify the needs and solutions for deployment in- and outside the EU.Methods: An evidence-based multidimensional matrix (type of threats, magnitude, location, societal impact) will be used to define the scenarios and missions justifying the use of CBRN deployable capacities. A state of the art of existing capacities within the EU and gap analysis will be carried out to identify actions for improvements and to assess the best possible organizational and operational architectures enabling sustainability at optimal costs for the society. The role of national or international regulatory authorities and agencies will be reviewed to assess which should be stakeholders of CBRN mobile capacities and how to coordinate the activities these EU mechanism of CBRN crisis management. A straightforward interface with existing EU capabilities and expertise will be delineated. A strong emphasis will also be put on other synergistic EU and non-EU projects. Practicalities (i.e., structures, equipments and functions including operational procedures, communication, logistics, forensics and related legal issues) will be assessed with technological suppliers and end-users. Building partnerships and cooperation with interested stakeholders (e.g., EU key actors, nations within and outside the EU in strong demand for this type of capacity) will be a specific task dedicated to the dissemination of th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'INNOVATIVE ENGINEERING OF GROUND VEHICLES WITH INTEGRATED ACTIVE CHASSIS SYSTEMS'.

assistant: **Objectives**

Innovation technologies in ground vehicle engineering require strong interdisciplinary and intersectoral investigations with an international dimension. In this context the project EVE proposes sustainable approach based on intensive staff exchange that leads to collaborative research and training between universities and industrial organizations from Germany, Belgium, Spain, Sweden, The Netherlands, South Africa, and the USA. The project includes basic and applied research, development design, experimentations, networking, and dissemination and exploitation activities. The research objectives are focused on the development of (i) experimental tyre database that can be used in the design of new chassis control systems and subjected to inclusion into Horizon 2020 pilot on Open Research Data, (ii) advanced models of ground vehicles and automotive subsystems for real-time applications, and (iii) novel integrated chassis control methods. It will lead to development and improvement of innovative vehicle components such as (i) an integrated chassis controller targeting simultaneous improvements in safety, energy efficiency and driving comfort, (ii) new hardware subsystems for brakes, active suspension and tyre pressure control for on-road and off-road mobility, and (iii) remote network-distributed vehicle testing technology for integrated chassis systems. The project targets will be achieved with intensive networking measures covering (i) knowledge transfer and experience sharing between participants from academic and non-academic sectors and (ii) professional advancement of the consortium members through intersectoral and international collaboration and secondments. The project EVE is fully consistent with the targets of H2020-MSCA-RISE programme and will provide excellent o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Dissecting the role of thymic epithelial cells in T lymphocytes maturation  during human foetal development', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

The thymus plays an essential role in the establishment of adaptive immunity and central tolerance as it provides a nurturing environment for the differentiation of T cells, a process orchestrated by their interaction with multiple cell types. Despite advances in the knowledge of human thymus, how it functionally develops during foetal life remains elusive. This project aims at dissecting molecular mechanisms responsible for functional maturation of T cells by recapitulating human foetal development within a novel in vitro 3D system. Stromal and T cell compartments will be isolated and characterised at relevant developmental stages before and after mature T cells appear to underpin when thymic stroma acquires competence to sustain T cell development. Stromal populations from relevant developmental stages will be expanded in vitro to be cocultured with T progenitors within a unique 3D thymic natural matrix developed by the host lab. Repopulated 3D scaffold is sliced according to clinical grade protocols and cultured, allowing to set up multiple coculture conditions with the same stroma and compare the output on T cell maturation. In parallel, foetal thymic epithelial cells will be genetically modified to determine the role of specific transcription factors important for T cells onset during development. Recently developed microfluidic devices will provide an additional layer of information regarding molecular mechanisms regulating the crosstalk between stromal and immunological compartments. I anticipate to recapitulate human T cell development within a novel, whole human 3D in vitro culture system, to tackle fundamental immunological questions regarding human thymus development including maturation of tolerogenic T cells and regulation of central tolerance.  Last, new k
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Cell type-Specific Disease Resistance Against Vascular Xanthomonas Plant Pathogens' to be submitted under Horizon Europe.

assistant: **Abstract**

Plants restrict entry of pathogens through physical barriers, and via Plants restrict the entry of pathogens through physical barriers and an innate immune system that recognizes pathogenic activity and initiates immune responses to halt the infection. As pathogens employ distinct infection strategies to invade plant tissues, immune responses are not uniform but rather specific for different cell and tissue types. This highlights the need to challenge the current concept of plant immunity and expand it towards a tissue-specific perspective. Vascular pathogens belonging to the bacterial genera Xanthomonas and Clavibacter exploit hydathodes –small multicellular organs at the leaf margin, which extrude xylem sap and are directly connected to the vasculature– as entry point into the plant. Currently, we have little understanding of the immune mechanisms in hydathodes. To address this knowledge gap and overcome technical challenges of studying molecular processes in localized and low abundant hydathode tissue, I propose an ambitious and timely project using state-of-the-art approaches: 1) My goal is to identify elicitors, which are perceived by receptors in hydathodes, triggering immunity by using activity-guided screening of pathogen extracts and mass spectrometry. 2) I aim to isolate and characterise hydathode-inhabiting commensal microbes that play a role in plant protection by, amongst others, laser-microdissection of hydathode tissue and (spatial) microbiota profiling. 3) To dissect cell-specific responses towards pathogens and commensals and to identify hydathode-specific immune pathways, recently available single nucleus RNA sequencing combined with live-cell imaging of fluorescent reporters will be applied. Overall, hydathodes are a unique system to study both tissue
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'interSectIonal iNClusion in delibeRation and participatiON with Youth' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

SINCRONY aims to ensure the meaningful inclusion of youth who experience social disadvantage and marginalisation in deliberative and participatory processes (DPP). The project will target the factors and processes responsible for reproducing political inequalities in youth engagement in deliberative and participatory processes based on intergenerational and intragenerational power imbalances and youth intersectional positionalities. The goal is to offer policymakers, public servants, researchers, teachers, youth workers, facilitators of deliberative processes, and youth CSOs concrete instruments, guidelines, and solutions to renovate deliberative and participatory practices implemented in public governance and schools. The consortium of nine partners, consisting of seven universities, the ALDA European network of local democracies, and an SME focusing on communication and dissemination, will contribute multidisciplinary and multi-methodological expertise in psychology, education, sociology, political science, gender studies, social research, intersectionality, and media analysis. A Stakeholders’ Collaborative Network, including expert advisors, local municipality representatives, schools, civil society, and youth organisations, will also be engaged throughout the project. Together, they will: (a) enhance the inclusivity of deliberative practices in two local municipalities (in Italy and Finland); (b) design, test, and deliver an innovative, co-constructed intersectional approach called the Intersectional Participatory Action Research-and-Deliberation, piloted in seven local municipalities and four schools (in Italy, Portugal, the UK, and Denmark); (c) design participatory formats; (d) create tools; (e) define ethical guidelines. By improving the democratic quality, incl
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Bioengineering key regulatory structures in insulin-secreting cells for stimulus-secretion studies in experimental diabetes research' (1994-1998) targeting Fourth Framework.

assistant: **Abstract**

Research objectives and content The primary objective of this research is to bioengineer pancreatic beta cells suitable for mechanistic studies of enzyme regulation and later gene therapy of diabetes. At a first step, molecular biology techniques would be used to correct the impaired glucose-sensing apparatus of the popular RINm5F insulin-producing cell line. This would be achieved by overexpression of the two key elements responsible for beta cell glucose-recognition, glucokinase and the GLUT2 glucose transporter. This surrogate beta cell model, would also prove useful for in-depth studies of the regulation of lactate dehydrogenase activity. The overexpression of lactate dehydrogenase should provide a novel means of elucidating its importance in determining the fate of glucose metabolic flux towards mitochondrial oxidation, which is believed to becritical for insulin stimulus-secretion coupling. This innovative research project should yield a number of important new insights into the pancreatic beta cell stimulus-secretion coupling pathway, in addition to generating novel cell lines useful for gene therapy approaches and available for European experimental diabetes research. Training content (objective, benefit and expected impact) The purpose of this training is to gain practical expertise in a spectrum molecular biology techniques to complement biochemistry methods I acquired during my doctoral research. This training would provide me with all the necessary skills for a future career in experimental diabetes research. Links with industry / industrial relevance (22)
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Setting-up a network of Technology Dissemination Centres to optimise SMEs in the olive and olive oil sector' under Sixth Framework.

assistant: **Concept**

Olives and olive oil are known for its beneficial effects on human health, mainly due to its protective action over the skin and cardiovascular and skeletal system. These foods are basic elements in the Mediterranean diet. Countries in this area are not only the main producers but also the ones with most consumers of them. The idea underlying this project is that this source of health should not be restricted to the producers located in the Mediterranean region. In fact, it would be highly recommended that olives and olive oil were part of the regular diet not only in European countries, but also in the whole world. To achieve this goal, the producing companies need to be reinforced, since most of the companies in Spain, Greece, Italy and Portugal are small and medium enterprises (SMEs), mainly family companies. This project stresses the need to reinforce SMEs and is in perfect agreement with the actions reflected in the European Union document Evaluation of the impact of the main market- organization measures in the olive oil sector, (1995-2000), and with the result of the last opinion poll carried out by the European Commission (Innobarometer) to the enterprises managers. The project is based on four pillars: To achieve a modern SME, with qualified staff, that employs the new technologies in order to access information and, in general, to all the technological innovation system; an SME concerned in the optimisation of the product quality and seriously committed in the treatment, recycling and re-use of all the wastes generated in its activity. Finally, partners have been carefully chosen attending to the following criteria: a) Countries with the highest number of SME's belonging to the olive and olive oil sector (Spain, Italy and Greece) b) Countries where the consump