RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Recessions, labour-market uncertainty and health' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

My postdoctoral project for the Marie-Sklodowska-Curie fellowship deals with recessions and health. The aim of the proposal is to provide a comprehensive analysis of how individual health is affected (both in the short and in the long-run) when recessions cause uncertainty on the labour-market. To achieve this aim, I will exploit two major recessions – the 2008 Great Recession and the 1990s Swedish recession – as well as particularly rich administrative data to answer two well-posed and policy-relevant questions: (1) Do individuals who experience major labour-market uncertainty during by recessions suffer from health disorders in the short-run? (2) Do recessions at career entry negatively affect health over the life-course – and in particular in the long-run? To adress these questions, the proposal will tackle two related and complementary specific objectives:(1) Analyse the short-term consequences of the drastic cuts in art subsidies in the Netherlands in the wake of the 2008 Great Recession – which triggered major labour market uncertainty in the art sector – on health outcomes for individuals in the art sector.(2) Investigate the long-run health effects of graduating in the 1990s Swedish Great recession using an innovative life-course perspective.Both the framework and the methodology used in these two projects are challenging and new. First, I exploit natural experiments as exogenous shocks on labour-market conditions, which allows deriving causal estimates. Second, I use particularly rich linked administrative data over long periods of time, which enables me to take a life-course perspective. I strongly believe that this unprecedented combination of the original concepts, the methodology, that is completely new to the field, and my particularly large and rich datas
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Biodiversity and Security: understanding environmental crime, illegal wildlife trade and threat finance.' to be submitted under Horizon 2020.

assistant: **Abstract**

The core intellectual aim of BIOSEC is to explore whether concerns about biodiversity protection and global security are becoming integrated, and if so, in what ways.  It will do so via building new theoretical approaches for political ecology. Achim Steiner, UN Under-Secretary General and Executive Director of UNEP recently stated ‘the scale and role of wildlife and forest crime in threat finance calls for much wider policy attention’. The argument that wildlife trafficking constitutes a significant source of ‘threat finance’ takes two forms: first as a lucrative business for organised crime networks in Europe and Asia, and second as a source of finance for militias and terrorist networks, most notably Al Shabaab, Lord’s Resistance Army and Janjaweed.   BIOSEC is a four year project designed to lead debates on these emerging challenges. It will build pioneering theoretical approaches and generate new empirical data. BIOSEC takes a fully integrated approach: it will produce a better conceptual understanding of the role of illegal wildlife trade in generating threat finance; it will examine the links between source and end user countries for wildlife products; and it will investigate and analyse the emerging responses of NGOs, government agencies and international organisations to these challenges. BIOSEC goes beyond the ‘state-of-the art’ because biodiversity protection and global security currently inhabit distinctive intellectual ‘silos’; however, they need to be analysed via an interdisciplinary research agenda that cuts across human geography, politics and international relations, criminology and conservation biology.  This research is timely because in the last two years, the idea that the illegal wildlife trade constitutes a major security threat has become more p
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Direct Current – Power flOws in megawatt-scale Energy gRids' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

The current electric energy distribution grid—based mainly on alternating current (AC)—has servedus for over a century. Transporting energy generated at large power stations over long distances to a distributed network of consumers. It is starting to show its shortcomings due to a rise in localgeneration with renewable energy sources and the essentially direct current (DC) nature of manymodern electric loads.Modern grids need to deal with two-way energy flows, local intermittent generation fromrenewables and local energy storage in stationary batteries. Medium voltage distribution microgridsusing DC instead of AC hold the promise to address the shortcomings of the AC main grid.There are several initiatives in low voltage secondary distribution grids, and DC-POWER is expandingtheir concepts into the medium voltage range. We propose the D3Bus, a bipolar DC bus operating at ±1.5 kV. Compared to standard 3-phase 400V AC distribution the D3Bus can reduce distributionenergy losses by over 90%, reduce downtime, equipment cost, and space requirements whileincreasing sustainability.DC-POWER demonstrates, tests and validates the D3 Bus concept in two operational pilots: Onepowering an industrial-scale hydrogen electrolyser stack at 2 MW power, and one powering a newdata centre with up to 500 kW installed IT power. Both pilots include sizeable solar PV arrays (200kW), while the data centre also includes a directly coupled DC UPS solution.In order to realise these pilots, DC-POWER develops several DC-DC converters, an AC activefrontend, as well as system protection components and a power/energy management system.The D3Bus is intended as a first stepping-stone towards standardization of MVDC distributionmicrogrids. It is such industry-wide standards that will enable and accelerate t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Exploring Novel Drivers of Anti-Microbial Resistance' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

Antibiotic resistance (AMR) is a major public health issue, with 5 million deaths in 2019 linked to AMR worldwide. These numbers are comparable to the toll of the SARS-CoV-2 pandemic. Without new solutions, AMR is projected to soon become one of the leading causes of death in the EU. Addressing this challenge requires the development of new, effective antibiotics, but this alone is not sufficient due to the rapid evolution of bacteria. Understanding the drivers and mechanisms of AMR is vital to delay or reverse resistance in both existing and new antibiotics, especially since no new broad-spectrum antibiotics have been developed since the 1990s and their development is a lengthy process with high attrition rates.The ENDAMR doctoral network aims to better equip researchers in Europe to understand and develop new strategies to tackle AMR. WP1 focuses on how AMR affects the fitness of pathogenic bacteria in the gut microbiome, aiming to identify microbiome characteristics that predispose to AMR infections and to explore microbiome-based interventions. WP2 examines AMR acquisition via horizontal gene transfer, investigating evolutionary pathways, host genetics, environmental factors, dissemination, and AMR reservoirs. WP3 is dedicated to understanding the frequency, mechanisms, and clinical implications of antibiotic resistance, with a particular focus on the less studied aspects of heteroresistance and tolerance, and to developing diagnostic tools and predictive models. WP4 explores the combination of antibiotics to enhance treatment outcomes and potentially prevent or reverse AMR, based on understanding the interplay of resistance mechanisms.ENDAMR will also prepare doctoral candidates for various career paths beyond academia, including teaching, science communication, an
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'ENABLING THE PREVENTION OF REBOUND EFFECTS OF SUSTAINABILITY-ORIENTED POLICIES'.

assistant: **Objectives**

Never before has there been a stronger global focus on the development of sustainability-oriented policies. Nevertheless, ca. 47% of their potential sustainability gains are never achieved due to rebound effects, negative consequences of sustainability-oriented interventions due to behavioural and systemic changes.REBOUNDLESS POLICIES aims to develop, test and demonstrate a comprehensive toolbox for the identification, simulation, and prevention of potential rebound effects of sustainability-oriented policies. The toolbox will consist of an expert system of rebound mechanisms, a configurator for the ex-ante simulation of rebound effects magnitude, and a catalogue of reboundless policy measures. The toolbox is targeted at sustainability-oriented policy advisors supporting evidence-based public policy making at the local, national and regional levels, incl. parties’ advisors and lobbyists, research agencies, non-governmental organisations, think-tanks, consultancies, and academic institutions.The project draws from the ERC-funded project REBOUNDLESS, which is enabling a paradigm shift for preventing rebound effects by design, with a focus on the design of products, product/service-systems and socio-technical systems. REBOUNDLESS POLICIES departs from the current recognition of the urgency in addressing rebound effects within policymaking to the demonstration of the REBOUNDLESS POLICIES toolbox potential, in close collaboration with policy advisors.Ultimately, the REBOUNDLESS POLICIES toolbox will enable policymakers to effectively simulate and prevent potential rebound effects of policies, enabling the achievement of intended sustainability gains.


**Keywords:** rebound effects, policy-making, sustainability
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Future Service Oriented Networks' in the context of a Seventh Framework call.

assistant: **Objectives**

The Future Service Oriented Networks (FUSION) project will develop a new networking architecture designed to natively support efficient provisioning, discovery and execution of service components distributed over the network. Today's cloud computing architectures are centralised and network-agnostic. This makes them unfit for geographically distributed services with tight QoS-constraints and high bandwidth and computation demands. FUSION will develop an architecture allowing combined service instantiation and network routing at a fine granularity. Dynamic instantiation of services close to the consumers will naturally adapt to variations in demand. The project tackles the problem by integrating service provisioning and service-centric networking. An important dimension will be to define lightweight interactions between the two layers for efficient cooperation without overburdening the network layer with service-specific logic.<br/>The service instance placement problem can be formalised as provisioning service component instantiation points, given the location and capabilities of infrastructure, varying demand patterns and the QoS requirements of the service. Moreover, when service components are replicated, native network support will facilitate the creation of new instances associated with a given user or session. The key challenge of service-aware networking is the routing and load-balancing of service requests to the best instances with minimal impact on the routing information tables, given the existence of many different potential service instantiation points in the network. To support dynamic service instantiation, the project will also design lightweight component-based virtualisation technology with reliable isolation properties, as well as service description
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Single-cell spatiotemporal analysis of Mycobacterium tuberculosis responses to antibiotics within host microenvironments', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), is an intracellular pathogen that killed 1.6 million people in 2017. Despite its enormous relevance for TB treatment, how intracellular environments affect the response of Mtb to antibiotics remain poorly characterised. This gap in knowledge is mainly due to the lack of appropriate technologies that have precluded comprehensive understanding of the response of intracellular pathogens to antibiotics, critical to design rational interventions. Here, I propose to use cutting-edge imaging approaches to define: (i) Mtb responses towards specific host-subcellular microenvironments by single-cell live long-term imaging in infected human stem cell-derived macrophages (iPSDM); (ii) the dynamics of antibiotic-mediated killing mechanisms using mycobacterial fluorescent reporters and high resolution correlative microscopy and (iii) the spatial and metabolic features of the Mtb response to antibiotics in vivo using a TB mouse model.For this, I will capitalise on technologies developed in the host group to quantify Mtb localisation and replication at the single-cell level combined with correlative electron microscopy (CLEM and CLEIM) approaches. This project will challenge the current limits of high content imaging by combining iPSDM with micro-patterning technologies for single-cell analysis. This will allow the identification of Mtb responses to antibiotics in host cells and how different intracellular microenvironments impact this process in cellulo and in vivo. Together, this proposal has the potential to uncover novel mechanisms of action of antibiotics in human macrophages, opening new avenues for a deeper understanding of human TB treatment and facilitate the discovery of new antibiotics.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'PHYSICAL BREAST ANTHROPOMORPHIC MODELS AND TECHNOLOGY FOR THEIR PRODUCTION' (PHENOMENO) targeting Horizon 2020.

assistant: **Abstract**

Breast cancer is the most common incident form of cancer among women bellow seventy years of age. Early diagnosis is recognized as a critical factor that improves the chance of survival. In this research, anthropomorphic physical three-dimensional models of the breast are necessary, whenever a real tissue background is required to investigate the detectability of lesions, the performance of image processing algorithms, the reconstruction algorithms, the whole imaging chain and to replace real breast in virtual clinical studies. Manufacturing of such phantoms, however, is still not widely accepted due to cost and challenges of current 3D technology, limited number of suitable printing materials and availability of anthropomorphic computational models. This project aims to form an international network of organizations working on a joint research programme on the development of a complete technology for the production of physical models of the breast based on their computational models. The overall goal is to utilize partners’ experience and expertise to improve research, researcher training and skills and increase knowledge transfer from research to practice, which will be achieved through international and intersectoral collaboration and staff exchange. Expected results are related to new methodology for design of anthropomorphic breast phantoms, new methodology for producing materials and a methodology for development of a prototype of complete equipment and relevant technology for the fabrication of realistic breast phantoms, structures or part of them including health and cancerous tissues. An application in x-ray imaging is targeted. The consortium is with an expertise in rapid prototyping technology, modelling, validating and use of anthropomorphic phantoms, softwa
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for '3rd Euroconference on Marine Natural Products' under Fifth Framework.

assistant: **Concept**

Natural Products Research has become a key discipline of the life sciences. The development of new pharmaceuticals and of crop protecting agents heavily relies on the discovery and understanding of novel molecules capable of specifically interacting with living organisms. In the infective disease and cancer areas, the share of natural product-related compounds exceeds 60 % of the newly approved drugs. Science has to answer, e.g., to the upcoming antibiotics crisis exemplified by the resistance of certain tuberculosis-causing bacteria against -lactam antibiotics and even vancomycin. The understanding of the chemical interactions between organisms is mandatory for progress in ecology. The world's oceans compose over 70 % of the earth's surface and 90 % of the volume of its crust. Over the past 30 years, sessile invertebrates, algae, and marine microorganisms have proven to be rich sources of novel, biologically active natural products. Important examples already brought to the market include the anti-inflammatory pseudopterosins and, recently, ecteinascidin 743 as anti-cancer agent.Although European research facilities are excellent, the vast majority of scientific contributions originate from research groups located in the USA and in Japan. The European research activities in Marine Natural Products Chemistry have to be further strengthened. The proposed conference will be characterized by the intense discussion of a large number of young, talented researchers from Europe with experienced, internationally renowned scientists from universities and industry.To ensure the maximum benefit for the younger participants, all of the following, major research topics in the interdisciplinary field of Marine Natural Products Research will be addressed: isolation and structure eluci
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Between evolutionary games and life history theory' (MATHECOEVO), addressing dissemination and exploitation.

assistant: **Impact**

The objective of this project is to develop mathematical structure that will be connection of evolutionary game paradigm with life history theory. In classical life history optimization models there are no interactions among individuals or density dependence: Life history evolution usually ignores density and frequency dependence. The justification is convenience, not logic or realism" (Stearns 1992) On the other hand, in classical game theoretic models there is no age or stage structure. Payoff describes averaged lifetime activity of an individual, which can be found for example in Cressman 1992: "...an individual's strategy is fixed over lifetime or, alternatively, the life history of an individual is its strategy.". Objectives of the project can be divided into three branches: a) Development of method of decomposition of entire population into subgroups (multipopulation replicator dynamics). This generalization of standard replicator dynamics approach will allow to game theoretic modeling of structured populations, divided into subclasses (different species, sexes, age or stage classes). b) Description of the dynamics of turnover of individuals. Explicit consideration of births and deaths instead of fixed Malthusian parameter will allow to include tradeoffs between mortality and fecundity to dynamic game theoretic models c) Derivation of game theoretic payoff functions due to the methods of life history theory. This approach will allow to formulate crossover problems where life history traits and phenotypic may affect interactions among individuals. Classical optimization of life histories approach investigates how ecology affects evolution of life history parameters. New approach will allow to model how life history parameters affect ecology of a population by deter