RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Absorption of light, macro-algae and the atmosphere""' (ALMA-MATER).

assistant: **Innovation**

The biogeochemical cycle of iodine is driven by sea-to-air exchange processes that are particularly relevant for the coastal environment, since they strongly influence the atmospheric chemistry in the marine boundary layer. Many aspects concerning the precursors and sources of iodine in coastal areas are still poorly understood. Quantitative data on the magnitude of gas fluxes and the composition of gas mixtures (iodocarbons or molecular iodine) escaping from the sea is essential for models describing aerosol formation and the influence of the corresponding gaseous species on the radiative balance of the Earth and hence on global change. However, data obtained under realistic conditions is sparse due to a lack of technologies that meet the challenges involved in taking meaningful in situ measurements.ALMA-MATER addresses this problem by applying a new optical method based on broadband cavity-enhanced Fourier Transform absorption spectroscopy. This approach is to be developed in order to identify and characterize biogenic emission sources of iodocarbons (e.g. macro-algae). It is planned to study specimen under controlled stress conditions in the laboratory.The proposed research into a long-standing atmospheric problem is inherently linked with plant physiological questions, and tackles this genuine environmental science challenge with the development of new spectroscopic technology in an ultimately multidisciplinary way. The project thus offers a variety of opportunities for the acquisition of new complementary research competencies and professional skills which strongly promote the career prospects of the fellow running the research. Hosting the project in Ireland is highly advantageous due to the nature of the topic. Thus the mobility of the exceptionally promising (In
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'High-throughput and reproducible development of intestinal organoids by microfluidics encapsulation in synthetic niches for intestinal bowel disease research' to be submitted under Horizon 2020.

assistant: **Abstract**

Intestinal bowel disease (IBD) is a chronic immune-mediated disorder characterized by a complex spectrum of multifactorial disorders, which affects 2.5-4 million people in Europe with a total annual healthcare cost of €4.6-5.6 billion. The unknown aetiology of IBD, along with its heterogeneous and multifactorial nature, make essential the development of novel disease model platforms that enable the fundamental understanding of the disorder. My project aims to develop the next generation of human intestinal organoids (HIOs) in reproducible and high-throughput fashion by microfluidics encapsulation in synthetic niches. This scalable technology will provide a well-controlled mass production of HIOs for disease modelling, drug screening of novel therapeutic targets, and regenerative medicine applications, filling the translational gap with organoids research. I will co-culture HIOs with immune cells and microbiota to obtain native physiological similarities and to develop the next generation of HIOs, which can effectively recapitulate the complex multifactorial spectrum of IBD and allow the identification of new insights into the pathophysiology of the disorder. MSCA Fellowship will provide me with a unique opportunity to exploit my diverse skill set and take fully advantage of available facilities and partnerships of Prof. Andrés García and Prof. Abhay Pandit, who are uniquely positioned to maximize the output of this project and benefit my future career. I will be trained in both discipline-specific and complementary technical training and generic and complementary transferable skills training through an inter-sectoral secondment on a CÚRAM’s industrial partnership to translate this innovative therapeutic technology to the clinic. The disruptive technology developed throu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'CHEMiRNA: Chemical-based Platforms for micro-RNA Detection. Towards Novel OncomiR Assays' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

Thos proposal present novel reagents and tools for the detection and quantification of microRNAs (miRNAs) with a particular focus on miRNA species involved in solid tumours and hematologic cancers. The proposed project will thus provide a new chemical toolbox which will allow the rapid detection of miRNAs involved in cancers. This proposal intends to take advantage of the novel dynamic chemistry approach to profile directly nucleic acids and develop based on it novel tools to provide simple, sensitive, rapid, multiplexed assays to profile miRNAs. The longer-term vision is that this dynamic chemistry approach will enable clinicians to be able to rapidly and accurately diagnose and prognosis cancer by combining the precision of the high affinity molecular probes and novel set of biomarkers based on miRNAs. Therefore, the proposed project is positioned at the interface of chemistry, biology and pre-clinical medicine with three main aims
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Farming high value algae with industrial gas emissions' under Horizon 2020.

assistant: **Concept**

"The European Union is one of the most advanced regions regarding environmental regulation, but the rest of the World, in both developed and developing regions, is increasingly adopting similar measures. In addition, the growth of demand of energy and goods plays against these objectives increasing the emissions. Thus both the need and demand of solutions to reduce emission is expected to grow exponentially and globally for the following decades.Currently, industries worldwide face the challenge of reducing the emission of CO2 and NOx incorporating less pollutant technologies, investing in the mandatory BATs, transforming their business toward less polluting products and services or simply assuming lower economic performance due to the environment protection costs derived from regulation. The impact of regulation in industry is particularly relevant in the case of European Industry. Being one of the early adopter regions of these measures, in some cases it reduces their competitiveness in favour of companies of less environmentally concerned countries.The BIORECYGAS technology, developed and pilot tested by ALGING, has demonstrated that removes 95% of CO2 and NOx from a simulated flue gas, beating the average 70-90% efficiency of the BAT technologies from NOx elimination and reducing 95% the need of CO2 emission allowances. These results have been validated by an independent source testing firm that is certified by the California Air Resources Board.In addition, BIORECYGAS uses the extracted CO2 and NOx as feedstock to grow Chlorella and other algae strains  producing a biomass stream. This is raw material for products currently available and demanded in the market like: protein and sugar-rich agricultural products, protein rich foods and nutritional supplements, select
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Accelerating mass loss of Greenland: firn and the shifting runoff limit', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Meltwater running off the flanks of the Greenland ice sheet contributes roughly 60% to its mass loss, the rest being due to calving. Only meltwater originating from below the elevation of the runoff limit leaves the ice sheet, contributing to mass loss; melt at higher elevations refreezes in the porous firn and does not drive mass loss. Therefore any shift in the runoff limit modifies mass loss and subsequent sea level rise. New evidence shows surface runoff at increasingly high elevations, outpacing the rate at which the equilibrium line elevation rises. This research proposal focuses on the runoff limit as a powerful yet poorly understood modulator of Greenland mass balance. We will track the runoff limit over the full satellite era using two of the largest and oldest remote sensing archives, Landsat and the Advanced Very High Resolution Radiometer (AVHRR). We will establish time series of the runoff limit for all regions of Greenland to identify the mechanisms driving fluctuations in the runoff limit. This newly gained process understanding and a wealth of in-situ measurements will then be used to build firn hydrology models capable of simulating runoff and the associated runoff limit over time. Eventually, the firn hydrology models will be applied to reconcile estimates of Greenland past, present and future mass balance. Covering the entire satellite era and all of Greenland, the focus on the runoff limit will constitute a paradigm shift leading to major advance in our understanding of how vulnerable the surface of the ice sheet reacts to climate change and how the changing surface impacts runoff and thus Greenland's role in the global sea level budget.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'The Integrator-centric approach for realising innovative energy efficient buildings in connected sustainable green neighbourhoods' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

PROBONO brings together a European multidisciplinary consortium of 47 partners, construction and consulting entities, public asset service managers, municipalities, technology solution providers and experts, to turn the six European districts (PROBONO´s Living Labs) into Green Building Neighborhoods (GBN), with positive energy balance and zero carbon emissions: two large-scale demonstrators (Madrid and Dublin) and four living labs representing business/owner promoters of the green buildings and neighborhoods’ transition (Porto, Brussels, Aarhus, Prague).PROBONO will provide strong examples of how GBN's technological and social innovations can be applied, with a vision focused on building infrastructure and a renewed focus on people and sustainability, taking full advantage of digitalization and smart technologies for the benefit of society. The adoption of the PROBONO approach and innovations will be proposed through a range of participatory methods that promote stakeholders (including citizens) partaking in co-designing and co-delivering a sustainable GBN. PROBONO will provide GBN Strategic Planning Tools in spatial, economic, technical, environmental regulatory, and social context aligned with city and urban masterplans and policy frameworks. PROBONO will create evidence-based policy recommendations, standardization actions, and robust adoption and commercialization strategies supported by a capacity-building program and a European Alliance of GBN Innovation Clusters. PROBONO will provide a GBN Digital Twin (DT) implemented across the LLs as a virtual representation of associated GBN including operational assets that implicate environmental and efficiency KPI. A cloud-based decision support-planning tool will be created to develop an optimized design for carbon-neutra
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'CURE HEARTandBRAIN  postdoctoral COFUND programme by CNIC'.

assistant: **Objectives**

The CNIC (Spanish Centre for Cardiovascular Research) is a worldwide recognised research centre dedicated to cardiovascular research. CNIC’s mission is to improve cardiovascular health in the society by generating scientific knowledge, efficiently translating that knowledge to the clinic, and providing new researchers with a comprehensive training. CNIC, awarded with the HR Excellence in Research since 2013, proposes to run a postdoctoral fellowship programme “CURE HEART & BRAIN” that will offer a total of 12 positions in the incoming mobility type for the selected and eligible candidates (holding PhD and compliant with MSCA mobility rules). During the COFUND grant life (5 years) there will be two calls (M2 and M9), each offering 6 fellowships. The Programme will advertise the positions internationally.The fellows will be able to choose the supervisor at CNIC and to propose research projects in all the research disciplines available at CNIC. The selection of the proposals will be transparent, based on merit and performed by external international peer-reviewers. CURE HEART & BRAIN fellowship programme will be open to excellent researchers of any nationality. The programme will offer training to develop key transferable skills and competences, foster innovation, entrepreneurship, promote Open Science practices, FAIR data management, and public engagement. The fellows will acquire new skills through advanced training, international, interdisciplinary and inter-sectoral mobility. CURE HEART & BRAIN includes 24 Associated Partners (12 from private sector) from all over the world and from different sectors, providing translational elements to the programme (secondments, training, supervision). The overall goal of the programme is to enhance the creative and innovative potent
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Identifying Inflammatory Bowel Disease causative genes through trans-eQTLs mapping within GWAS loci' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

Life-time prevalence of inflammatory bowel disease (IBD) is reaching an alarming rate of > 1/400 in industrialized societies.  Improved understanding of disease pathogenesis is essential to develop more effective preventive, diagnostic and therapeutic measures.  Genome-wide association studies (GWAS) have identified ~ 160 risk loci contributing to inherited predisposition to Crohn's disease and/or ulcerative colitis.  While this has already led to the identification of new perturbed pathways and potential drug targets, causative genes and variants remain unknown for the vast majority of risk loci.  Moreover, the identified risk loci only account for an estimated 25% of inherited risk. GWAS loci are likely to be regulatory and therefore alter expression levels of other genes. In the present project we propose to apply an integrated genomic and transcriptomic approach to identify novel genes and pathways that are causally involved in inherited prediposition to IBD. We aim to detect causative genes implicated in IBD’s susceptibility through the evaluation of trans-eQTLs within GWAS loci. Trans_CEDAR is based on the generation of an integrated dataset of nine cell/tissue types collected on 350 healthy caucasians individuals, as well as on the use of next generation sequencing to identify rare variants in functionally-incriminated candidate genes. We expect to detect new causative variants that may constitute new drug targets. The present project will also generate a map of trans-eQTL in different tissues, equally useful for the study of other diseases, to be shared with the scientific community.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Information Day for Hungarian students and young researchers on career possibilities in the European Research Area'.

assistant: **Objectives**

The Hungarian higher education system is renowned for its excellence, both in technical and social sciences. However, many graduates do not find appropriate jobs in the country. Young researchers are often employed in poorly paid temporary positions with a low chance of finding stable employment in a reasearch institution. For them, information and assistance with European opportunities is crucial and can be instrumental in the continuation of their career as a researcher.The Association of Hungarian Women in Science – a Civil Society Organisation – together with EURAXESS Bridgehead Bay Zoltan Ltd. and the Central European University (CEU) will jointly organise a series of Inspiring Science Workshops and a large-scale ERA Mobility and Career Day in Budapest to enhance the career prospects of graduate students and young researchers from all fields of science. The events will be hosted by the partners with the latter taking place in the campus of CEU. Research organisations from several countries, international organisations and multinational companies will be invited to inform the participants on European research funding and career opportunities offered by them in a job fair format. Pre-arranged interactive meetings between the employers and potential employees will complement the fair.Practical workshops on career development (CV drafting, interview tactics, presentation skills), information sessions addressing the EURAXESS portal, career resources, personalized assistance tools to overcome the barriers of researchers’ mobility will maximize the knowledge of young researchers and students and help them starting a career in European research institutions. A workshop on Responsible Research and Innovation, with special regard to gender issues, will target all participant
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Challenged Internet Access Network Technology Infrastructure' (CHIANTI), addressing dissemination and exploitation.

assistant: **Impact**

At the time the Internet was designed, end systems were stationary and interconnected through permanent, wired links. Support for highly mobile hosts that frequently switch access technologies was not a design objective. However, nomadic and mobile hosts will dominate the market and there is high demand for ubiquitous connectivity. Still, in the foreseeable future, the goal of providing always connected" network access for mobile users will not be met, as wireless links are always subject to limitations: in geographical coverage, due to interference, and obstacles on the radio link, but also for economic reasons.The Challenged Internet Access Network Technology Infrastructure (CHIANTI) project will improve disconnection and disruption tolerance for mobile user communications relying on the unmodified core Internet architecture.  This is achieved by deploying a new service-support infrastructure - operated by a third-party as an overlay or closely integrated with an operator network - that complements the core IP and mobility functionality to sustain operation and performance of business and consumer applications: Remote file access and email, interactive web access, end even real-time media streaming maintain a satisfying user experience and full business productivity even under intermittent connectivity.In the highly dynamic environments experienced by mobile users, a communications service should utilize available link-layer access technologies according to configurable criteria such as bandwidth, latency, and - often neglected - cost. It is a key goal for the CHIANTI architecture to co-exist with and benefit from the presence of existing and emerging "always best connected" solutions. Based on a cross-layer approach, transport and session protocols, performance enhan