RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Multi-messenger soft-field spectroscopy of molecular electronics at interfaces' (SoftMeter).

assistant: **Innovation**

The real-time interrogation of molecular electronics at the interface between different media is key to understanding the fundamental mechanisms at the basis of processes such as catalysis, solar energy harvesting, and charge transport in optoelectronic devices. Such an investigation ultimately requires attosecond temporal resolution and picometer spatial accuracy, to capture in real-time the energy exchanges mediated by the electron wave function and the competing structural changes of the target. Experimental strong-field-laser physics has been demonstrated to provide outstanding spectroscopical methods for this purpose, such as high-harmonic generation spectroscopy, attosecond science, and laser-induced electron diffraction. However, it also presents intrinsic limitations such as high peak intensities, low efficiency, and poor tunability. These obstacles have so far hindered its application to the study of high-complexity systems, for example complex interfaces.SoftMeter aims at filling this gap. We are proposing a novel multi-messenger two-color spectroscopy, namely soft-field spectroscopy, that converts the concepts of strong-field physics into the moderate or weak field regime and overcomes its limitations, while still providing an unprecedented spatiotemporal resolution. The new protocol will be developed in the first phase of the project: It is based on an interferometric setup combining few-fs ultraviolet pulses with few-cycle IR pulses, and on the multi-messenger measurement of the laser-induced electron diffraction and the high-harmonic radiation of the target. In the second phase of the project, the novel soft-field scheme will be employed for the real-time interrogation of electronics at molecular interfaces.SoftMeter will pave the way for a new class of ul
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Connect2Scale - Uniting European Investors and Scaleups' (Connect2Scale).

assistant: **Innovation**

Connect2Scale creates partnerships between five Business Angel networks - Estonia, Finland, Latvia, Lithuania, and Slovenia - and two supporting organizations - European Business Angel Network and Civitta - with the aim of enabling the growth of European start-ups through joint efforts. The project focuses on knowledge transfer from venture capital firms to business angels to close the gap between funding cycles and introduce cross-border investment opportunities in the EU in a harmonized way. Combining unique competences and extensive networks of partners, the consortium aims to direct venture capital funding to start-ups from the moderate/modest ecosystem and to spread the resulting knowledge of the project to a wider circle of investors across the EU.


**Keywords:** Business angels, Venture Capital, Investment Gap, scaling-up, cross-border investments
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'CAncer PAtients Better Life Experience' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

After the primary intervention, most of cancer patients are managed at home, facing long-term treatments or sequelae, making the disease  comparable to a chronic condition. Despite their benefit, strong therapeutic regimens often cause toxicity, severely impairing quality of life. This may decrease adherence to treatment, thus compromising therapeutic efficacy. Also due to age-related multimorbidity, patients and their caregivers develop emotional, educational and social needs. CAPABLE will develop a cancer patient coaching system with the objective of facing these needs/issues.The time is right to fully exploit Artificial Intelligence (AI) and Big Data potentialities for cancer care and bring them to patients’ home. CAPABLE will rely on predictive models based on both retrospective and prospective data (clinical data, data from unobtrusive environmental and wearable sensors, data from social media and questionnaires). Models will be integrated with existing clinical practice guidelines and made available to oncologists.Thanks to the mobile coaching system for patients, CAPABLE will allow identifying unexpected needs, and providing patient-specific decision support. This feature, together with the chance of discovering unknown adverse effects of new treatments, makes CAPABLE more than a personalised tool for improving life quality, an advance for the whole research community. Our team includes complementary partners with experience in data- and knowledge-driven AI, data integration, telemedicine, decision support. In addition, the involved patients’ association gives a unique opportunity to access thousands of questionnaires on patients’ needs, which will inform the system design. The project addresses EU priorities such as shifting care from hospitals to home to face s
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Toxicity of anthropogenic multi-stressed soils under a global warming perspective' (GLOBALTOX) targeting Horizon 2020.

assistant: **Abstract**

Concept: Global climate change is displayed as a set of stressors (increasing temperature and CO2 levels, decreasing soil moisture content, higher UV radiation exposure) potentially impairing both biotic and abiotic ecosystem components. This may worsen in environments degraded by human activities where organisms have to deal with multiple stress factors, i.e. in multi-stressed environments, and the toxicity of the contaminants present may change depending on climate conditions. GLOBALTOX aims at assessing how the toxicity of anthropogenic multi-stressed soils may be affected under the current global warming perspective, using soil invertebrates as bioindicators along with soil physicochemical and microbiological parameters.Methodology: An inter/multidisciplinary ecotoxicological approach will be applied to soils from different environments with high human pressure (metal mining and agricultural areas), different soil invertebrate species (collembolans and enchytraeids) and single and multiple combinations of different climate factors (air temperature, soil moisture content, atmospheric CO2 concentrations and UV radiation). Climate factor combinations will be based on the emission scenarios predicted by the IPCC by the year 2100. For a complete overview of the problem, the project will rely on changes in key soil parameters (pH, organic matter, nutrient cycling, microbial community) and soil invertebrates (body metal concentrations, enzymatic biomarkers, DNA-damage, gene expression) to understand the effects at organism/population level (survival and reproduction).Impact: The foreground derived from the project will improve the environmental risk assessment of anthropogenic-degraded areas under future scenarios of climate change. GLOBALTOX will promote the social percep
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Lithography Enhancement towards Nano Scale', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Water immersion lithography has been widely accepted as patterning technology for the 45nm technology node, but solutions for the patterning of 32nm and 22nm technology nodes are not clear yet.EUV lithography is not yet available for industrial use, in spite of the impressive progresses registered till now, while multiple beam e beam lithography is still in development. Double patterning seems to be the only viable option to support the development of future process generations in a cost effective way and within the time limits defined by ITRS roadmap.Its main advantage consists in enabling the definition of structures beyond resolution capability of existing lithographic tools, without drastic changes in manufacturing infrastructures or huge investments. Two alternative approaches are possible, both based on existing immersion scanners:Double exposure, which implies two subsequent exposure steps, and the use of different combinations of hard masks or innovative resist materials and development process;Pitch doubling based on a single lithography exposure followed by the formation of spacers, by material deposition and etch-back, also in combination with CMP.Both approaches are being actively investigated, but they are still far from maturity. Among the problems to be solved there is the control of mask to mask alignment, for double exposure, and the control of the thickness of deposited layers, of defects and of profiles, for pitch doubling. Common concerns are cost, size control and the partitioning of the design. The pitch doubling approach is the more advanced, specially for memories, while double exposure could have a broader application, but will require improvement to equipment.The consortium includes all required competences to develop all elements of the supply
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'ESQ-FP: Erwin Schrödinger Quantum Science Programme' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Based on the Austrian scientific excellence strategy, the Erwin-Schrödinger Center for Quantum Science and Technology(ESQ) has recently been launched as a new nation-wide research initiative. ESQ is coordinated by the Austrian Academy ofSciences (OEAW), under the auspices of the Ministry of Science, Research and Economics, in close collaboration with theVienna University of Technology (TUWIEN), the University of Vienna (UNIVIE), and the University of Innsbruck (UIBK). Atpresent, 28 research groups cooperate in research and training programmes in quantum science and technology. ESQ willserve as a EU hub for Experienced Researchers and ESQ teams will contribute to the European Quantum FlagshipInitiative, as well. ESQ supports in particular postdoctoral careers and innovative projects in quantum research and it willgain additional visibility and momentum through the MSCA COFUND program fostering interdisciplinary inter-sectoralresearch. ESQ supports incoming international fellows in developing their scientific careers. The ESQ fellowship programmeoffers mentoring by scientists, who were selected for their scientific excellence and it builds on an excellent infrastructure atall partner organizations. ESQ provides an extensive international scientific network and many options for personneldevelopment and acquiring transferrable skills, also with industrial partners. For that purpose, the fellows will also be offeredextended academic and inter-sectoral secondments. The ESQ fellowship programme will publish one international call peryear to recruit up to 15 fellows distributed over three selection rounds and 54 months. The selection process follows theprinciples of excellence and transparency and will be supported by a high-level, international selection committee. The ESQfell
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fifth Framework proposal on 'Urbiomath2002'.

assistant: **Innovation**

Dynamical systems constitute a fundamental mathematical and computational framework within which many processes in biomedicine can be described. From tumour growth to hormonal regulation, from the spread of disease to neuronal transmission, the crucial feature of many biological and natural phenomena is their evolution in time. Differential equations are the historically established mathematical tool for the study of dynamical systems; within these, differential equations with delay have recently emerged as a field rich in applicative possibilities and interesting structural behaviour. Computationally intensive techniques have also enjoyed in recent years, increasing recognition, in the wake of the more widespread availability of cheap computing power.The possibility of numerically computing solutions for classically posed (but analytically intractable) differential models has made it possible to identify their parameters from observational and experimental data, providing the medical practitioners with estimates of the quantities most directly useful to them (like the transfer rates of substances between different body compartments). This evolution has even prompted the re-framing of some medical problems in terms of the results of specific model fits to standardised experimental data. With steeply increasing medical care costs, advancing diagnostic technology and heightened expectations from the community, mathematical modellers will find more and more occasions to work in the medical field. The biomathematics looking for exposure to medical problems and to young biologists and physicians intending or employ mathematical tools in their research; it intends to focus on the interplay between delay differential equations, computer-intensive methods and parameter estimati
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Unlocking the Dynamics of Dopamine in Aging: Balancing Pre- and Post-Synaptic Mechanisms for Optimal Brain Function across the adult lifespan', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Many older adults experience impairment of cognitive functions, such as memory. While changes to the aging brain are often assumed to underlie cognitive decline, but it has turned out surprisingly hard to identify coupled brain-cognitive changes in aging. This challenge is magnified when searching for potentially modifiable brain alterations that could serve as targets for various kinds of interventions. A promising candidate mechanism is age-related alterations in neurotransmitters like dopamine (DA) and noradrenaline (NA), crucial for brain functions. Yet, existing models of aging related to DA and NA are inadequate, as past studies solely focused on either the DA or NA system and also emphasized a single facet of the multifaceted DA system (either pre- or post-synaptic). This represents a serious omission because various parts of the DA system are tightly regulated and the balance between pre- and post-synaptic markers, rather than each marker in isolation, might be more critical for efficient neuromodulatory function. Contrary to the prevailing notion of a global DA neurodegeneration, characterized by a hypodopaminergic condition, I hypothesis that aging is accompanied with loss of balance between pre- and post-synaptic DA systems. This imbalance holds profound implication for functional brain integrity and cognitive decline in aging. The overarching goal of this ground-breaking research program is to, for the first time, address the fundamental question of how the dynamic interplay between pre- and post-synaptic markers of the DA, along with its interaction with equally critical NA, evolves as individuals age and how these dynamics are linked to functional brain integrity and cognitive decline. Of particular interest is whether transiently restoring the balance bet
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Molecular Basis of Intelligence'.

assistant: **Objectives**

Ionotropic Glutamate receptors (iGluRs) influence the timescales at which neurons communicate with each other. The dynamics and flexibility of the response of iGluRs to neurotransmitter binding give rise to the synaptic plasticity responsible for normal human intelligence. Dysfunction of the iGluRs is causally responsible for diseases such as Alzheimer's and Amyotrophic lateral sclerosis.  It is therefore medically important to understand how the structure-function relationship in the iGluRs operates at the molecular level. Many drugs attempt to target iGluRs to treat neuropathologies. However, due to the inherent complexity of the dynamics of iGluRs it is difficult to accurately target the causative function of the iGluRs thus making it difficult to form a viable pharmaceutical strategy, without insight into the dynamics of iGluRs at the atomic level.  Additionally, although the individual members of the iGluR family are structurally very similar, they display very different kinetic and allosteric behaviour. The proposed project aims to focus on the comprehensive picture of the comparative dynamics of the members of the iGluRs. In close collaborations with experimental and computational methods development groups, I plan to investigate how the relatively small differences in the structures of the iGluRs give rise to the complex behaviours of the iGluRs. This will be accomplished via state of the art Molecular Dynamics (MD) simulations and a large library of computational thermodynamics techniques.  From this dataset, using Machine Learning (ML) techniques in combination with Markov State Models (MSMs) I will create robust and testable models that can determine the commonalities and variances between the dynamics of the members of the iGluRs while throwing light on thei
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Modelling of morphology Development of micro- and Nano Structures' (MODENA) under Seventh Framework.

assistant: **Objectives**

MoDeNa aims at developing, demonstrating and assessing an easy-to-use multi-scale software-modelling framework application under an open-source licensing scheme that delivers models with feasible computational loads for process and product design of complex materials. The use of the software will lead to novel research and development avenues that fundamentally improve the properties of these nanomaterials.As an application case we consider polyurethane foams (PU), which is an excellent example of a large turnover product produced in a variety of qualities and of which the properties are the result of designing and controlling the material structure on all levels of scale, from the molecule to the final product. Polyurethanes are used in furniture, automotive, coatings, construction, thermal insulation and footwear, which are the most important industry sectors. Tailoring these properties requires understanding and detailed modelling of the fundamental material behaviour on all scales.An open-source software-suite will be constructed that logically interlinks scale and problem specific software of our university groups, using a software orchestrator that communicates information utilizing our proposed new communication standard in both directions, namely upwards to the higher scale and downwards to the lower scale. This feature is unique, enabling the solution of complex material design problems.By that this project contributes to strengthening the European leadership in design and production of nanocomposite materials with functional properties in general. It will also contribute to strengthening European SME positions in the development of computationally intensive simulation software. Finally, it will contribute to making production processes more efficient by combin