RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'It’s (also) what you produce: Experimental Evidence on Creating Markets for Quality in Low-income Countries' (MISSINGMARKETS).

assistant: **Innovation**

Half of the world's extreme poor  or over 430 million people  live in Sub-Saharan Africa. The vast majority live in rural areas and work in agriculture, where productivity is desperately low. This keeps welfare low now  and in the future  as agricultural productivity increases are seen as a condition for both structural transformation and to avoid the worst impacts of climate change. This is the motivation for bringing the green revolution  which has so far bypassed the continent  to Sub-Saharan Africa. Despite the logic being compelling, the results from a decade of research on technology adoption in African agriculture have been largely disappointing. Interventions aimed at increasing farmers ability to invest in inputs to produce more of what they already do have not proven transformative. In this research proposal, I will investigate a complementary explanation why income and productivity in African agriculture remain low: it is what farmers produce  precisely the quality and value added of their output  that keeps them poor, and they produce low quality because there is no demand for smallholders to produce high quality or higher value-added outputs. As low quality limits price and thus farmers' potential income, missing markets for quality can help explain the low returns to farming. At the core of this research proposal is the hypothesis that markets for quality are missing because of a fundamental information problem: quality is a difficult to observe characteristic. I will rely on three multi-wave randomized controlled field trials to study technological and institutional solutions to overcome this information problem, which hamper demand for high quality products in the export market (work package I) and at home (work package II). In the final work package, I
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Studying at high energies the dynamical and non-thermal processes in astrophysical outflows', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Powerful relativistic outflows are associated to the brightest sources in the sky. These sources reach their large luminosities at very high energies through non-thermal emission. The relativistic particles responsible of this non-thermal emission are the result of different acceleration mechanisms, which can take place in different regions linked to these outflows. The production of relativistic particles is very sensitive to the local conditions, and therefore their radiation probes the physical properties of the plasmas in which they are generated. Several objects are perfect places to study the physics of relativistic outflows: pulsars, microquasars, and active galactic nuclei (AGN). Depending on the source, these outflows can be either collimated (jets) or wide (winds). Nowadays, the main unknowns of jets and winds concern their formation mechanism, the way how they propagate and dissipate energy, the role of the environment to trigger emission and  mass-loading, and the way how they terminate and the global impact on the medium. We aim at answering, studying the high energy emission from relativistic outflows, the following questions: the content and structure of jets in microquasars and AGN at their formation region; the propagation of these jets; the impact of pulsars on their environment in binary systems at all scales; the radiative and dynamical consequences of these outflows when terminating. Different techniques will be used to achieve our goals: semi-analytical modeling; numerical (magneto)hydrodynamical simulations; numerical calculations of radiation transfer; and multiwavelength observations.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Concrete containment management using the Finite Element technique combined with in-situ Non-Destructive Testing of conformity with respect to design and construction quality' (CONMOD) under Fifth Framework.

assistant: **Objectives**

Safety-related concrete structures such as concrete containments are subject to ageing processes, which can reduce their safety as well as functional lifetime. Serious problems have also been known to occur to these structures due to defects caused at the construction stage. In order to establish the actual status of concrete containments it is necessary to apply investigative techniques that are capable of providing information about the internal structure and condition of the concrete and reinforcing. By using the Finite Element (FE) method it is possible to study the behaviour of concrete containments under various loading conditions and thus to identify critical sections. This information can then be used to plan non-destructive testing in order to obtain a more accurate description of the true nature of the structure at these points. Subsequently this new information can be used as input to the FE models to allow more realistic behavioural predictions. The model can be modified with time by repeating the investigative process at intervals. This process includes the use of Non Destructive Testing (NDT) to monitor changes in the chemical and physical properties of the concrete and if applicable to quantify deterioration processes. The condition assessment and ageing management of concrete containments will thus be based on realistic evaluations.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Tools to access and analyze un-reduced mass spectrometry data to accelerate access to biotherapeutics' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Biotherapeutics, such as monoclonal antibodies (mAbs) and antibody-drug conjugates (ADCs), constitute an increasingly important class of molecular drugs. Accelerating our society’s access to novel biotherapeutics-based therapies and diagnostic tests for existing and new clinical indications, including those caused by COVID-19, is critical. The exceptional specificity and selectivity of mass spectrometry (MS) renders this analytical technique a powerful tool in development of biotherapeutics-based drugs and clinical diagnostics. Nevertheless, even Orbitrap Fourier transform mass spectrometry (FTMS), which dominates the high-performance MS field, may demonstrate limited performance in structural analysis of the very complex mAbs and ADCs. Indeed, while the user-accessible Orbitrap data (processed mass spectra with reduced information) may be of a sufficient quality and information content for small molecule and isolated proteins analysis, it is not for the complex biotherapeutics. We identified the limiting factor that inhibits biotherapeutics structure analysis being the absence of hardware and software tools to acquire (access and provide to the end-users) and analyze the un-reduced data (e.g., time-domain signals or transients). With these tools in hands, the end-users would be able to increase performance and productivity of their biopharma workflows on the Orbitraps (e.g., leading to increased sensitivity and resolution, and thus leading to faster identification of more species and their deeper sequencing), as well as create novel workflows, not possible otherwise. The A2MStools (access & analysis MS tools) aims to address this limitation by: (i) providing access to the currently unavailable un-reduced data (transients) for the Orbitraps FTMS platforms with enabled B
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Enantioselective separation of Racemates by extraction using Chiral Metal Complexes based on modular Chiral Ligands obtained by parallel synthesis' (ENANTIOSEPARATIONS).

assistant: **Innovation**

Traditional methods of production of enantiopure compounds include separation of racemates by crystallisation of diastereomeric salts, enzymatic resolution and increasingly also asymmetric catalysis. All these methods have certain advantages and may well b e the cheapest method for a particular chiral compound. However, in all cases the selection and optimisation of the method may take considerable development for each separate case and is still very much guided by a trial-and-error approach. An alternative approach to those described above for the separation of racemates, relies on the ability of chiral host compounds to discriminate between the two enantiomers of a racemate, thus allowing the physical separation of the enantiomers.We plan to adopt a very promising method, namely the enantiomeric separation of racemic mixtures by extraction involving the selective coordination of one enantiomer to a hydrophobic chiral metal complex in the organic phase and the extraction of the uncomplexed enantiomer in the aqueous phase. The main objective of this project is the design and synthesis of chiral metal complexes for the enantioselective separation of racemic mixtures of entire classes of compounds (e.g. carboxylic acids, amino acid derivatives, hydroxy acids, but also amine derivatives) by extraction. Libraries of chiral ligands (ca. 100-125 compounds) will be synthesized in a parallel format, starting from a variety of chiral diamino or aminoalcohol scaffolds, and other chiral reagents (beta-aminosulfonyl chlori des, Boc-amino acids) as well as salicyl aldehydes.Purification by chromatography of the intermediates and of the final products will be avoided by using solid-phase scavenger resins. The chiral complexes with transitions metals will then be synthesized and the s
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fourth Framework proposal on 'Concept evaluation of low cost lithium polymer battery system for electric vehicles'.

assistant: **Innovation**

Objectives Lithium polymer is recognised at one of the best performing, least toxic, potentially safest and cheapest battery technologies. This technology is therefore one of the most promising for the EV application. This project concerns industrial process research and lithium-ion polymer battery development for the EV application. The project also concerns system design, implementation and test of an electric car equipped with an integrated lithium-ion polymer battery system with the following specification:  Energy Content: 20 kWh  Power Content: 30 kW  Weight: 200 kg max.  Volume: 125 l max. Technical Approach The technical realisation of the lithium-ion polymer battery for electric vehicles specifically addresses:  The design of cell and battery components  Optimisation of the manufacturing technology  Development of the battery system peripheral equipment (electronic control, thermal management)  Test and control of batteries (performance, safety, cell balancing) Expected Achievements and Exploitation The project passes through a sequence of design, manufacturing and test analysis prior to the implementation and evaluation of the complete battery system in an electric vehicle. The following steps and advances are expected:  Specification and test of a new process for high volume/low cost lithium-ion polymer battery manufacturing.  Manufacturing of larger quantities of 40-50 Ah cells.  Laboratory and bench test of 40-50 Ah cells according to EUCAR test procedures.  Simulation of cell behaviour under load conditions, cooling system sizing, and device for a standardised EUCAR electric vehicle. Design and specification of new electronic control system for lithium battery systems in electric vehicles.  Implementation, test and demonstration of the battery system in an
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Food web changes in response to increasing temperature and varying nutrient status: an experimental approach on freshwater mesocosms' in the context of a Sixth Framework call.

assistant: **Objectives**

Shallow lakes have suffered the sudden loss of transparency and vegetation subject to human-induced eutrophication. Restoration to their original clear state is of great social and scientific interest. Therefore, there is a great concern on the possible negative influences of increasing temperatures on their recovery. A key aspect for their recovery is the interactions of macrophytes and algae with nutrients, and their control by grazers, which are in turn preyed upon by fish.Although these interactions have been described, the ecological processes behind them are not well understood. Therefore, this proposal aims to study the ecological processes behind the establishment of the clear / turbid state of shallow lakes and its interactions with different thermal scenarios. Special focus will be directed at the trophic dynamics of zooplankton and their role in shallow lake food webs. In order to accomplish this objective I will join an ongoing multidisciplinary experiment in Denmark. In this project, mesocosms consisting of 24 enclosures have been established and flow-through heated systems are used to mimic the predicted seasonal variations in temperature expected to occur during the period 2071-2100 in Denmark. Sediments from many different natural shallow lake s are used as colonisation bank.I will study changes in abundance and biomass of selected species and undertake detailed analysis of stoichiometric composition, fatty acids, amino acids and isotopic signatures of the different food web compartments, with special focus on zooplankton. Addition of 15N will provide new information on turnover rates, which complemented with specific experiments on trophic fractionation should give a solid basis for correctly interpreting the mesocosm changes shown by stable is otopes.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Associative mechanisms linking a defective minipuberty to the appearance of mental and nonmental disorders: infantile NO replenishment as a new therapeutic possibility'.

assistant: **Concept**

The miniNO project aims to identify the key causative mechanisms of the lifelong multimorbidity associated with preterm birth. Prematurity is associated with alterations in the maturation of the hypothalamic-pituitary-gonadal axis, and specifically with its transient activation during infancy, known as minipuberty.  miniNO will study for the first time the association between premature birth and alterations in minipuberty and infantile nitric oxide (NO) signaling in the brain, and comorbidities that appear later on in life. The project is based on robust preclinical data and previous clinical studies, and will exploit data concerning premature birth and minipuberty in existing cohorts as well as newly created cohorts. We will identify the molecular association between NO deficiency, altered minipuberty and multimorbidity combining mental (e.g. autism, social cognition, learning and memory impairments) and non-mental disorders (e.g. anosmia, hearing loss, metabolic abnormalities, cardiovascular impairements and infertility) as well as gender, environmental and lifestyle factors. For this, we have assembled a unique interdisciplinary consortium of renowned basic scientists (neuroscientists) and clinicians (pediatric and adult endocrinologists, psychiatrists, geneticists) and an SME to implement the project results. By validating the causative mechanisms of the multimorbidity related to preterm birth, we will propose and develop novel diagnostic and preventive tools, including screening tests for biomarkers and newly identified genetic factors, for altered minipuberty, thus paving the way to personalized treatment and new therapeutic options very early in life. miniNO is expected to improve the quality of life of millions of prematurely born individuals and reduce the fina
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fourth Framework proposal on 'Development of sustainable aquaculture of arctic charr.'.

assistant: **Concept**

The project focuses on the development of aquaculture of the salmonid fish arctic charr (Salvelinis alpinus). Aquaculture of arctic charr is in its initial stages but is clearly growing in Europe. This trend is also apparent in Canada. In order to ensure profitability and competitiveness, this new industry is in great need of organized research and developmental work.In subtask A1 five microsatellite primers have been developed that provide good resolution in detecting stock specific genetic variation. This is a significant milestone for the project. In subtask A2 genetic samples have been provided from a number of wild arctic charr populations in Iceland and Scotland. Biological and physical data were obtained in the respective freshwater systems.In subtask B 1, data from Iceland and Sweden have been organized for future analysis. In B2 significant variation in performance genes, has been detected in two Icelandic and one Swedish aquaculture stock of arctic charr. In subtask B3 gene-environment rearing experiments are ongoing in Iceland and Sweden, involving several strains of arctic charr. The environment in these experiments differs primarily with regard to temperature. Performance parameters such as growth patterns, sexual maturity, oxygen consumption and food intake are estimated regularly. In subtask B4 experiments have been ongoing linking variation in early development performance, mainly metabolic rate, with later performance. Studies to identify differential gene expression in high- and low metabolic rate charr are ongoing and have already returned preliminary results.In general, the project is progressing as planned. The main achievement of the project at this stage is the development of microsatellite primers. Secondly, the detection of polymorphism in perfo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Exploring Digital Participation with Children to Co-produce Knowledge for Active Neighbourhoods using SoftGIS methodology in Delhi, India' (DigiPACK) targeting Horizon Europe.

assistant: **Abstract**

DigiPACK aims to demonstrate the potential of innovative digital participatory tools for mapping and comparing active mobilitybehaviour and localized experiences with children across their gender, age, socio-economic status and settlement typologies withinthe Global South context. The key research objectives are: (1) to adapt and contextualize SoftGIS methodology for enabling digitalparticipatory planning with children in India; (2) to map and compare childrens active mobility behaviour (mode of transport,accompaniment, home-school route) and environmental experiences (location of meaningful places, frequency of visits, perceivedenvironmental fears and likability index) across four dimensions of age, gender, socio-economic status and urban settlementtypologies using SoftGIS; and (3) to evaluate the potential of SoftGIS methodology to integrate within Indias urban planning policyframework. Adopting a comparative case study approach, the SoftGIS data will be collected from children aged 10-17 years frommiddle and lower-middle-income families across three distinct neighbourhood settlement typologies of Delhi and analysed usingquantitative statistical techniques. Actor-Network-Theory will be employed for evaluating the role of SoftGIS in the participatoryplanning policy framework. The project results, including contextualized digital methodology and new knowledge on how age,gender, socio-economic status and urban settlement influence childrens active mobility behaviour, will open up new researchavenues and have the potential to revolutionize participatory urban planning with children in India, and the Global South morebroadly. The 2-year project will be hosted by the Department of Built Environment, Aalto University, whose leading expertise inpioneering the SoftGIS methodol