RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Understanding and Alleviating Inequalities in Digital News Consumption' (INEQNEWS), addressing dissemination and exploitation.

assistant: **Impact**

This projects vision is to understand and develop strategies to mitigate inequalities in digital news consumption, the acquisition of political knowledge and vulnerability to misinformation. While inequalities in digital news access have been lowered with very high levels of internet access in many countries, there are indications that inequalities in digital news use and the benefits of being exposed to it, like the acquisition of political knowledge, are increasing. Academic literature has been instrumental in describing how digital intermediaries (e.g. social media or search engines) and different modes (mobile devices) have changed the way people consume news, however little attention has been given to how these changes manifest against the backdrop of pre-existing social inequalities in news use and the acquisition of political information. Thus, the project will a) reliably identify digital inequalities in news use, the acquisition of political knowledge, and vulnerability in online misinformation in countries of the Global North and the Global South. In its examination it will focus on b) long-standing informational inequalities related to social class, gender, and age and c) the role of new information technologies like digital intermediaries and mobile devices. Apart from identifying people with low levels of news use, this project will d) explore the ways that parts of the population navigate and face disadvantages in a complex digital media environment. Last, this project, will for the first time, e) test digital public health style interventions that could reduce inequalities in digital news use, political knowledge, and exposure to as well as belief in online misinformation. To achieve these objectives, this project will employ a novel set of methods. Overa
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Tamoxifen mediated protection on X-linked centronuclear myopathy: a mechanistic and pre-clinical study' in the context of a Horizon 2020 call.

assistant: **Objectives**

X-linked centronuclear myopathy (XLCNM) is a severe congenital myopathy caused by the absence of lipid phosphatase myotubularin. XLCNM affects 1/50.000 male births, there is no treatment and many cases lead to premature death. Thus, treatments are needed.Tamoxifen (TAM) is a selective estrogen receptor modulator that mimics estrogen signalling in skeletal muscle. Pilot study and previous results from the hosting group, have shown that TAM improve muscle symptoms and survival rate in XLCNM mouse model. Results strongly support the idea that TAM protects skeletal muscle via enhancement of estrogenic signalling positively modulating multiple pathways linked to muscle function. However, the exact mechanism(s) is not yet understood. This project aims at elucidating the mechanism(s) of action of TAM and evaluate further its efficacy in XLCNM mouse model. Two specific aims are proposed. First, to determine how TAM acts on pathways and key players involved in XLCNM. Estrogen signalling, phosphoinositide balance, autophagy and mTORC1 signalling will be determined in wild type and XLCNM mice treated and non-treated by TAM. Second, to investigate the pre-clinical efficacy of TAM combined with other compounds in XLCNM mice. TAM extends the lifespan of XLCNM mice according to the pilot study but it prevents only partly leg muscle atrophy, restricting complete functional rescue. Thus, TAM will be combined with other approved drugs that target muscle atrophy (everolimus, creatine, IGF-I and steroids).These parallel approaches will provide knowledge about not-yet explained events related to XLCNM and TAM effects, from molecular to in-vivo level, and instrumental information for other myopathies and rare diseases where lipid phosphatases are missing and phosphoinositide are unbalanced.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Secretarial support to the chair of EURAB 2005-2006' goes beyond current state-of-the-art under Sixth Framework.

assistant: **Innovation**

Work Programme: 2005-6Science & SocietyGrant to named recipient: Secretarial support to the chair of EURAB hosted by Wissenschaftszentrum (Vienna):up to 100,000 SSA to be implemented in accordance with article 9.2a of the Rules for participation and dissemination of the 6th Framework Programme.Administrative tasks (part-time) in support of Chair of EURAB:- Taking care of incoming e-mails including printing out of attachments- Answering e-mails, phone calls, and other correspondence in English, French and German- Preparation of EURAB Meetings- Reading, archiving and filing of documents- Organizing contacts with Working Groups- Internet search of documentation- Research assistance in the preparation of lectures- Assistance in updating of homepage- Preparation of travel / accounting- Photocopying of documents
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Living on the Edge: Tunable Electronics from Edge Structures in 1D Layered Materials' to be submitted under Horizon 2020.

assistant: **Abstract**

One of the driving forces of the ongoing nanotechnology revolution is the ever-improving ability to understand and control the properties of quantum matter even down to the atomic scale. Key drivers of this revolution are layered materials like transition metal dichalcogenides (TMD). The realisation of novel TMD-based electronic devices relies heavily on understanding the relation between structural and electrical properties at the nanoscale. Crucially, one-dimensional (1D) TMDs have been predicted to exhibit striking functionalities including metallic edge states, ferromagnetic behaviour, and mobilities that are not suppressed as compared to their 2D counterparts. Indeed, in the 1D nanoscale limit, the lateral edges of TMDs become dominant, opening novel opportunities to tune edge-induced electrical properties leading to i.e. enhanced charge carrier mobility. However, these predictions for novel phenomena in 1D TMDs lack experimental verification, due to the challenge in accessing the relevant information at the nanoscale. I propose to unravel the interplay between structural and electrical edge-induced properties by exploiting recent breakthroughs in electron microscopy (EM) allowing simultaneous unprecedented spatial and spectral resolution. I will focus on MoS2 nanoribbons, and use electron-energy loss spectroscopy to map the electronic properties at the nanometer-scale. Beyond the optimization of EM for 1D TMD characterization, I will investigate semiconducting-to-metal and ferromagnetic transitions by realising controllable edge structures. I have an extensive track record in pushing the frontier of EM characterization and growing nanostructures. I recently demonstrated the feasibility of pinning down the interplay between structure and electronic properties at th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Model-based Data Analysis of Transcription and Splicing' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Gene expression is the fundamental process that in all cells produces functional protein from a genomic DNA template using a messenger RNA (mRNA) intermediate. Eukaryotic gene expression involves transcription--the polymerization of mRNA--and splicing--the removal of non-coding regions from the mRNA. Recent evidence shows that nascent mRNAs are spliced while still being transcribed, not after completion of transcription, and that splicing machinery regulates transcription. This cross-talk complicates understanding of gene expression, as its mechanism and consequences are not understood. This project proposes using model-based data analysis, applied to multiple types of data, to study the kinetics of coupled transcription and splicing. Model-based data analysis is a statistical framework in which models are formulated as probability distributions encoding the stochastic interactions between components, including observed data. Knowledge of the underlying mechanism--here, biological--is used to quantify both the phenomenon, and the uncertainty resulting from partial knowledge and noisy observations. The need for such analysis is acute in modern biology: decades of molecular biology have yielded detailed information on specific molecules and pathways, and now next-generation sequencing (NGS) allows scientists to collect gigabytes of data on thousands of distinct molecules simultaneously. Yet, integrating these approaches is challenging: biologists struggle to analyze NGS data in ways that give insight into known--and previously unknown--biological mechanisms.Here, the model-based data analysis paradigm will be used to interrogate the interplay of transcription and splicing, using state-of the art data including time-resolved NGS measurements of RNA processing. Working with
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'e-ScienceTalk : Supporting Grid and High Performance Computing reporting across Europe'.

assistant: **Concept**

Over the last 10 years, the European Commission and governments have invested substantial funds in scientific grid computing. Scientists have access to state-of-the-art computational and data resources located around the world, putting European research into a leading position to address the greatest challenges facing us today, such as climate change, pandemics and sustainable energy.<br/>With the advent of the European Grid Infrastructure and the associated fundamental changes to the way that grid computing will evolve in the future, combined with the blurring of boundaries between grids, clouds, supercomputing networks and volunteer grids, a clear consistent source of information aimed at non-experts is now more important than ever, through dissemination projects that cross national boundaries.<br/>e-ScienceTalk will build on the outstanding achievements of the GridTalk project in bringing the success stories of Europe's e-Infrastructure to policy makers in government and business, to the scientific community and to the general public. E-ScienceTalk will work with the EGI and other collaborating projects to expand the scope of the existing GridTalk outputs, to report on the interactions of grids with e-Infrastructures such as cloud computing and supercomputing, and will also explore options for the sustainability of e-ScienceTalk's products.<br/>e-ScienceTalk will produce a series of reports aimed at policy makers to disseminate key policy issues underpinning grid and e-Infrastructure development in Europe and coordinate e-concertation activities. The GridCafé, GridCast and GridGuide suite of websites will cover new topics and explore novel web technologies, as well as integrating more closely with GridPP's Real Time Monitor to combine live views of grid activity with
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'End-to-end QoS through Integrated Management of content, networks and terminals' in the context of a Sixth Framework call.

assistant: **Objectives**

The ENTHRONE project proposes an integrated management solution, which covers an entire audio-visual service distribution chain including content generation and protection, distribution across networks and reception at user terminals. The aim is not to unify or impose a strategy on each individual entity of the chain, but to harmonise their functionality, in order to support an end-to-end QoS architecture over heterogeneous networks, applicable to a variety of audio-visual services, which are delivered at the various user terminals. To meet its objectives, the project will rely on an efficient, distributed and open management architecture for the end-to-end delivery chain. The availability and access to resources will be clearly identified, described and controlled all the way along the content distribution chain. The MPEG-21 data model will be used to provide the common support for implementing and managing the functionalities of the resources.The project addresses the scalable generation, protection, distribution and usage of multimedia content and resources in geographically distributed environments. ENTHRONE is also concerned with end-to-end QoS in terms of performance, at both the user and network levels and with the mapping between these levels. The adoption of the MPEG-21 framework in the project will contribute to the implementation of the Universal Multimedia Access (UMA) concept, which aims at achieving interoperable transparent access to multimedia resources from any type of client terminal or network. A high-level goal of the project is to bridge the divide between the content provision and the networking worlds, resulting in cross-industry co-ordination on both network and content management issues, and bringing focus to standards such as MPEG-21.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Selective extraction of minor actinides from high activity liquid waste by organized matrices' (CALIXPART).

assistant: **Concept**

High activity waste, which contain long life minor actinides, are currently vitrified for their storage in geological formation. In order to decrease the potential toxicity of this wastes the selective removing of these minor actinidesis studied in order to destroy them by transmutation. Currently the separation of americium and curium is a three stages process. Preceding projects showed the potentialities of the functionalized calixarenes which make possible to obtain a high intra class selectivity, for example for the alkali cations (separation cesium/ sodium) or discrimination of different lanthanides with respect to their size. In this project, calixarenes aimed to recover in one step americium and curium will be synthesized and studied. Moreover the process of extraction of cesium from the H. A. solutions by calixarenes-crown6 will be tested on real solutions in order to show the capacity of calixarenes to be implemented on H.A. solutions.During this project, 160 extractants were synthesised by the universities of Madrid, Mainz, Parma, Twente, Micromod, Katchem and the Institute of Inorganic Chemistry of Rez: calixarenes, cavitands, tripodal compounds, beads or dendrimers bearing different ligating sites like soft and hard donor groups, CMPO, malonamide, glycolamide, COSAN, TTFA...
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'On line measurement for preventing fouling when closing industrial process water circuit' (1994-1998) targeting Fourth Framework.

assistant: **Abstract**

SUMMARY The majority of industrial processes use aqueous fluids. The current trend is to reuse the water to a maximum in order to econornise on its consumption, and to produce the most concentrated wastewater possible in order to facilitate its subsequent elimination. Employing this type of practice comes up against sometimes redhibitory problems of circuit fouling due to the effects of deposits, formation of biofilm, and scale formations. The production of electrical energy alone accounts for 75% of the consumption of industrial cooling water. Increasing the concentration factor from 1 to 5 would allow a reduction of around 95% of the flows sampled. However, this increase leads to scaling and biofouling phenomena. The main objective of the project is to develop the scientific knowledge necessary to define and validate on-line instrumentation and measuring techniques regarding the fouling properties of aqueous process fluids when these are reused in a closed loop or have a very high level of recycling. OBJECTIVES The current trend regarding the use of aqueous process fluids is to promote their reuse in a closed loop (partially or totally) to the maximum, with a view to limiting both water consumption and pollution discharge. Employing this type of practice comes up against sometimes redhibitory problems of circuit fouling due to the effects of deposits, biofilm and scale formations. The main objective of the project is to develop the scientific knowledge necessary to define and validate on-line instrumentation and measuring techniques regarding the fouling properties of aqueous process fluids when these are reused in a close loop or have a very high level of recycling. The wealth of recent publications on biofouling alone (we have documented around one thousand) demonst
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Wind energy technology platform secretariat' goes beyond current state-of-the-art under Sixth Framework.

assistant: **Innovation**

The wind energy sector has proposed and developed a Technology Platform for Wind Energy, with the support and encouragement of the Member States, the wind industry, the European Parliament and the European Commission. The wind energy sector has produced its first, visionary document: Prioritising Wind Energy Research and the Technology Platform is set to be formally launched in the Spring, following the establishment of its Steering Committee. WindSec, the Platform Secretariat, will optimise the activities of the Technology Platform, and develop its infrastructure. WindSec will be the key driver, along with the active participation of its members, towards achievement of its objectives. These are to comprehensively model the market development and technology research needs and resources of the wind energy sector, with a view to cost reduction through economy of scale and new technology.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'A portable, multichanneled, inexpensive, non invasive 3-dimensional gait analysis system, developed for community use that is easy to use, provides rapid and accurate gait reports' to be submitted under Sixth Framework.

assistant: **Abstract**

Our idea is develop an efficient, reliable, cost-effective gait analysis system. Current systems are usually expensive, complex, large, non-portable, and can be difficult to use. Specialised gait analysis laboratories are extremely hi-tech and accurate in their diagnosis of human disorders or diseases. However, they are extremely expensive, difficult to set up and use, requiring significant expertise, normally centred around large cities, medical schools and in private clinics.Our technical objectives for SUREGAIT are to develop a portable, inexpensive, non-invasive, 3-Dimensional gait analysis system that can be used in the community. Being simple-to use, it can be set up by a nurse at a GP sugery, community centre, village/church hall, or even at a nursing home and be calibrated prior to use. As results at present can be obtained within five minutes, it is hoped that this can be further brought down to one minute. Due to its ease of use, it is envisiged that up to 20 patients could easily be analysed in a session.All the data from the various sensors and the matching video clips will be sent to a doctor, anywhere in the EU, with expertise in gait analysis via e-mail, or mobile phone technology, for diagnosis. In addition, the relatively low cost of the SUREGAIT technology will allow gait analysis to be available to anybody who requires it in all European Union countries. Each skin-mounted EMG sensor will allow force measurement and positional analysis of the patient. Sensors will be highly innovative in that they are truly wireless, running off low power, negating the need for the patient to carry heavy battery packs or trailing cables.To achieve this we need to develop appropriate digital communication network between all the radio sensors in the system triangulation