RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Multi-functional Analytical Focussed ion beam tool for nanotechnology'.

assistant: **Concept**

The project FIBLYS aims at developing an innovative nanostructuring, nanomanipulation and nanoanalysis instrument: a hybrid scanning probe (SPM) and dual beam focussed ion beam (FIB) instrument (including scanning electron microscopy (SEM) capabilities).   In addition to an instrument based on conventional dual beam FIB(SEM) technology, an SPM/FIB(SEM) microscope will use both techniques, integrated in a compact setup offering capabilities that not only combine the techniques but allow for nanoanalysis and nanostructuring/-manipulation options that the single instrument or sequential use of the techniques is  unable to achieve.   This FIBLYS hybrid device will allow to use all FIB capabilities while imaging the procedures with the integrated SEM. The SEM has the options of chemical analysis through Energy Dispersive X-ray analysis (EDX) and structural analysis through Electron Backscatter diffraction (EBSD).  The combination of SEM and SPM provides for the combination of nano-scale chemistry and crystallography imaging via electron-matter interactions (EDX, EBSD) with the information from tip-sample interactions like topography or magnetic/electrostatic force imaging.   Combining electron-matter and tip-sample interactions, the FIBLYS hybrid instrument will for the first time allow to probe with nano-scale resolution many electron-matter interactions like detection of electron beam induced current (EBIC), or cathodoluminescence or phonons, or backscattered electrons directly at the surface with cantilever based sensors.   This project will merge FIB(SEM) and SPM manufacturers at European level and reinforce their competitiveness. The partnership reflects the excellence and competences needed in this project, only possible through transnational co-operative research of s
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Development of a combined and automated hard turning and polishing production system – effective, automated, safe and integrated hard turning and polishing' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

European SMEs which produce high precision parts by means of hard turning are facing a steady loss of competitiveness in their growing markets since existing manufacturing technologies do not fulfil increasing demands on part quality and variety. During the last years the competition has worsen due to up-coming low wages countries outside Europe and an increasing cost pressure. Additionally these days the economic crisis causes a tremendous drop in orders. To sustainably ensure the survival and competitiveness of the SMEs a technology must be provided which enables a faster part-production with concomitantly better part-qualities. This technology has to consist of an automated production system integrated in one lathe which ensures a reliable flexible production of high-precision parts of hardened steel.To achieve this goal, the development of several components to be merged into an innovative production system for the reliable production of high-precision parts of hardened steel by means of the combined process of hard turning and polishing is obligatory. These components will encompass the following:- a new developed monitoring system will detect and avoid the generation of undesirable surface defects like so called white layers.- an optical measurement device will calibrate a new tool directly and measure the cutting edge geometry and wear of the tool in order to compensate form errors in conjunction with the controlling of the lathe- the system will be completed by a polishing device to be able to produce up to optical surface qualities.To reach the envisaged high-level efficiency of the production system concerning the quality and production times the process strategy of the combined process of hard turning and polishing will be developed. Thus the “easiTAP” system
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Accelerating a paediatric formulation of ivermectin for the control of Neglected Tropical Diseases' (IVM-KIDS) under Horizon Europe.

assistant: **Objectives**

Ivermectin is a critical drug for the control and elimination of multiple neglected tropical diseases. Currently, children weighing under 15kg do not receive treatment with ivermectin due to an absence of safety data and the lack of a suitable paediatric formulation. Consequently, these children are left untreated. This results in considerable morbidity at the individual level and a reservoir of infection at the population level. These issues create a critical barrier to achieving the goals of the 2030 NTD roadmap. In 2023, the World Health Organization (WHO) conducted a Paediatric Drug Optimisation (PADO) review to identify critical needs for therapeutics in children affected by NTDs. Recognising the central role of ivermectin in the control of NTDs, along with the opportunity to accelerate progress by expanding treatment to paediatric populations, this report highlighted a paediatric-friendly ivermectin formulation as  as a critical priority for NTD programmes worldwide. A novel orodispersible formulation of ivermectin provides the opportunity to address this critical gap. Our consortium brings together leading academic and drug development partners across Europe and sub-Saharan Africa to address this global priority need, with crucial experience in novel therapeutics and navigating the European and African regulatory landscapes.Our consortium will deliver studies to demonstrate the safety, pharmacokinetics and efficacy of the novel, orodispersible formulation of ivermectin suitable for use in young children. This will include conducting a large safety study across West, Central, East and Southern Africa to demonstrate the efficacy of this agent for the treatment of soil transmitted helminthiasis. We will work closely with European and African regulators to ensure tha
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'SLA-Ready: Making Cloud SLAs readily usable in the EU private sector' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Today, whilst many organisations are reliant on cloud resources, contracts for cloud services often contain Service Level Agreements (SLAs) with technical & legal provisions that are inappropriate, difficult to understand &/or illegal. Similarly, the application of established data protection concepts can be problematic, with uncertainties as to what is regulated, who is responsible & which laws apply. Building on the work conducted by EC SIG SLA, Certification & Code of Conduct, ETSI CSC, CSA WGs, ECP Steering Board, NIST, Gartner, SLA-Ready, delivers a reference model for Cloud SLAs & a set of best-practices & services to support cloud customers in the use of cloud SLAs through their life cycle. The latter will improve the uptake of cloud computing  by private sector, while procuring services across the cloud market. Other Outputs: • support cloud customers via a dedicated, social repository of Cloud SLAs and supporting services to ensure the acquisition, operation and termination of cloud services fulfilling specified requirements;• provide an active contribution to relevant SDOs like: ISO/IEC 19086.• engage & ensure coordinated, global collaborations with e.g., NIST RATAX and the CSA SLA WG for a collaborative, international approach;• Provide 4 engaging practical user friendly tutorials to end-users, • Showcase real efforts of the common reference model implementation in Europe. The consortium is lean, complementary & strong: TRUST-IT, a prime mover in cloud computing landscape ensures effective coordination, digital marketing & SDO liaisons; CSA a leading, global player in the arena of cloud security; TUDA, brings direct expertise on techniques & frameworks to operate with cloud SLAs; Arthur’s Legal represents IT, ISP, software, CSP, IoT & IT service vendors, end-
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Textiles and the Making of Israeli Modernism: From the Zionist Bauhuas to Feminist Art' (TMIM), addressing dissemination and exploitation.

assistant: **Impact**

The development of Israeli visual culture in the twentieth century was underscored by artists’ search for local roots, counterbalanced with their desire to dialogue with an international artistic arena. As in other settler societies such as the United States and Australia, the attempt to produce a distinguished idiom of Israeli modernism oscillated between ""nativism"" and ""universalism""––two seemingly opposed tendencies that were actually interrelated. Indeed, the historiography of Israeli visual culture has emphasized the ongoing tension between local versus global/universal influences. Nevertheless, scholars continue to debate which sources shaped Israeli modernism, and what political implications followed the incorporation of Middle Eastern traditions, European Jewish heritage, or international avant-garde movements into an Israeli national style. The proposed study would contribute to such debates by investigating a medium that has received little scholarly attention––textiles. Textiles and the Making of Israeli Modernism: From the Zionist Bauhaus to Feminist Art (TMIM) will focus on textiles produced in Israel during the 1940s–1970s within three separate yet overlapping fields of practice: an art and craft academy, a government-owned fashion brand, and the fine art establishment.  TMIM will draw and expand on recent scholarship that addressed the marginalization of textiles within art history due to its association with ""low,"" commercial, or ""feminine"" work, as well as the innovative field of object-oriented anthropology that considers ""things"" as agents of cultural and social meaning. TMIM aims to establish the significance of a group of highly prolific artists-designers, all female, whose work has been entirely overlooked. It is precisely its position at
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Harmless Clostridium bacteria as a highly targeted, continuous delivery system for immunomodulatory anti-cancer drugs' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

DualTPharma (DTP) is a new venture developing a highly-potent and proprietary line of targeted pharmaceuticals for personalised cancer treatment. Our mission is to broaden our current pipeline by developing a new class of dual drugs for cancer treatment which are well tolerated and can be taken orally. This novel solution comprises the application of non-pathogenic Clostridium bacteria as a novel tumour delivery vehicle for anti-cancer drugs to increase immunotherapy efficacy. Even though DTP has a multi-disciplinary team available in the oncology field, we lack the required expertise and skills in the bacterial genetic field to test the feasibility and lead the development of this new line of R&D. Therefore, the goal of this project, CMI2T IA, is to hire an Innovation Associate with expertise in the bacterial genetic field for our company, to determine the feasibility of this novel solution. The successful candidate is preferably a microbiologist with an interest in bacterial applications in cancer treatment and with strong expertise in bacterial genetics. During the first 12 months, the innovation associate will be involved with both technical and business-related activities. (S)he will be responsible for establishing the new line of R&D, with activities ranging from establishing and managing a new lab to, planning research, to performing hands-on laboratory work. More specifically, the research activities will include genetic modification of bacteria, and performing in vitro efficacy assays on human cell lines. From a business perspective, the Innovation Associate will critically contribute to a market study and the development of a business strategy of the new business unit. This position will open up new career opportunities for the Innovation Associate, by obtaini
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Mechanisms of toxicity of asbestos substitute mineral fibres: new approaches to hazard and risk assessment.' (FIBRETOX) targeting Fifth Framework.

assistant: **Abstract**

This project aims to support the hazard and risk assessment of asbestos substitute fibres. The potential for induction of inflammatory changes, oxidative stress, immunotoxicity and genotoxicity will be eximined for three substitute fibres (glass fibres, rock wool, wollastonite) and compared to that of amosite asbestos. Novel cell culture or whole animal systems will be employed to obtained information on the molecular mechanisms and the dose-response relationships governing the induction of the above toxic effects for use in human population studies. These biomarkers of exposure and early effects for use in human population studies. These biomarkers will be applied, together with already existing biomarkers, in biomonitoring studies of cohorts of fibre workers.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'The geometry of Higgs bundles', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Higgs bundles play a fundamental role in the current panorama of mathematics and theoretical physics through their many connections. Amongst the latter is the link with the geometric Langlands programme, a suitable generalization of the relation between a curve and its Picard variety, which moreover admits a natural quantum field theoretical interpretation. According to this, any G- local system on a curve yields a perverse sheaf on the moduli stack of G*-bundles (where G* is the Langlands dual to G). A simpler (abelianised) version of the geometric Langlands programme has been proven for Higgs bundles by Donagi and Pantev. A programme initiated by these two scientists aims at inducing the full Langlands correspondence from its abelianised version. Building on the work of the researcher and the hosts, we will fill in the gaps of this program and provide alternative tools broadening the current state of the art also beyond this action. In doing so, we will study central elements of the geometry of Higgs bundles from a new perspective. More precisely, we will give a way to understand the Bialynicki-Birula stratification via algebraic techniques, and, related to that, carefully study the irreducible components of the nilpotent cone, applying also the theory of SU(p,q)-Higgs bundles. Finally, we will explore the case of positive characteristic, with the aim to shed light on the Hecke eigenproperty in this setting.


**Keywords:** Moduli spaces, Higgs bundles, geometric Langlands programme, nilpotent cone, Bialynicki-Birula, stratification
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Quantum Information Processing in High-Dimensional Ion Trap Systems'.

assistant: **Concept**

Quantum processors have taken the binary paradigm of classical computing to the quantum realm and are starting to outperform the best classical devices. Yet, neither the underlying quantum information carriers, nor many of the targeted problems naturally fit into this two-level paradigm. In this project, I aim to break this paradigm. Instead of restricting the rich Hilbert space of trapped ions to only two levels, the proposed research will make full use of the multi-level (qudit) structure as a resource for quantum information processing. This will unlock unused potential within quantum processors and bring near-term intermediate-scale quantum devices into a regime well beyond classical capabilities. Furthermore, the availability of high-performing qudit quantum hardware will stimulate a rethinking of the way we approach quantum information processing. This ambitious goal will be achieved by designing and implementing a trapped-ion quantum processor, tailored for qudits. Building on the full toolbox of atomic physics, this device will benefit from ongoing developments for binary systems, while featuring significantly extended capabilities, including novel ways of interacting qudits for resource-efficient processing. Using this hardware, we aim to achieve two objectives: First, we will develop tools for and demonstrate native qudit quantum information processing from simulation to computation. Second, we will show that the platform outperforms not only qubit systems but also the best classical devices through the demonstration of a quantum advantage.I am convinced that this project will stimulate a number of research directions beyond its immediate goals, from application-tailored quantum computing, to advanced quantum communication and quantum metrology. My strong back
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Biomarkers for clinical assessment of lungs intended for transplantation' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Lung transplantation is the only therapeutic option for selected patients suffering from end-stage lung diseases. 80% of all donated lungs are not used for transplantation. The main reason is uncertainty of the function and quality of the lung. Ex vivo lung perfusion (EVLP) is a technique used to assess quality of lungs prior to transplantation. In collaboration with leading clinical scientists, XVIVO has developed solutions and systems for EVLP. EVLP has recently become internationally clinically accepted. More than 300 patients have received transplanted lungs that would otherwise not have been used. Centers establishing a clinical program for EVLP increase the number of lung transplantations significantly. Clinical outcomes are at least equivalent to outcomes for patients receiving standard lungs. However, in order to disseminate the EVLP technique to a broader range of hospitals, it is necessary to offer objective metrics assessing lung function in addition to the subjective assessment methods used today. Exploitation of EVLP has an impact for XVIVO. Each EVLP generates an income of about €15 000. Today about 5000 lung transplantations are performed each year. If we can reach 25% increase, it would contribute to a revenue increase of at least 18 MEUR. It also means that 1250 critically ill patients on the waiting lists will receive new lungs. The true potential is to increase the utilization rate of donated lungs to 40-60%. The project aims to carefully select optimal biomarkers in phase 1 and confirm validity and clinical relevance in phase 2 through a clinical study. By introducing new biomarkers, XVIVO will be able to commercialize a device that will broaden the company´s product portfolio and fulfill the customer need for validated tools making clinicians more c