RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Modelling and experimental investigation of 3-dimensional laser forming of metallic components' demonstrating excellence, impact and implementation quality for a Fifth Framework call.

assistant: **Abstract**

The aim of the project is to investigate a 3-dimensional thermo-mechanical model for analysis and prediction of fundamental laser forming mechanisms .The objectives mentioned below are required for realized research work.Objective 1: Familiarization with laser equipment at Liverpool Laser GroupObjective 2: Analysis of mechanisms of laser forming (e.g. Temperature Gradient Mechanism (TGM), Buckling Mechanism (BM), Planar upsetting or shortening mechanism) .Objective 3: Experimental study of laser forming effects which result from basic geometries of laser energy input, namely e.g. short line in central area, circle and arc of larger thin sheet.Objective 4: Development of a 3-dimensional thermo-mechanical model for the analysis of the laser forming mechanisms.Objective 5: Testing of the model with experimental results (prediction of laser forming mechanism ( s ) ; prediction of rate, direction, overall degree and uniformity of bends for primitive geometries)Objective 6: Extension of model and experiments to complex geometries (ex-tension to full width line bends on thin sheet (taking account of clamping forces & edge effects) ; extension to a series of lines, arcs and circles( to achieve uniform laser forming of saddle shapes and other double-curvature shapes); extension of model to predict the degree of forming in simple correction of distortion in structures (extrusions, hydro-formed tubes etc) ; extension of model to the prediction of laser forming of thick section metallic plate. Possibility of carrying out a research in The University of Liverpool will give the applicant a great opportunity to deal with technology and science at a high world standard level. Their laboratories are excellent equipped for complying of research project, e.g. wide range of high-power indu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Foresight action for knowledge based multifunctional materials technology' goes beyond current state-of-the-art under Sixth Framework.

assistant: **Innovation**

Materials research and science are among the main driving forces for innovative products and processes, however usually with long lead times. As stated in the section 3.4.2.3-4 of the Working Programme of the Thematic Priority NMP it is important to identify the leading European research groups and the main trends and bottlenecks in order to support the policy development and to strengthen the European leadership in this domain. This proposal aims at mapping of excellent groups and at identification of highly relevant research areas in the field of knowledge based multifunctional materials in the perspective of next 5 to 30 years. Therefore the focus will be put on the fields that are relatively new or that need still long time for successful technology implementation. The Specific Support Activity will consist of combination of forecast process including interviewing of experts aiming at scientific and technological relevance and of the analysis of recent foresight studies occupied with the aspects of economic prosperity, environmental and social change as well as public safety and security issues. Following a broad screening the search will be focused on a limited number of highly promising fields (materials hot spots) by involving experts from academia and industry. On this basis road maps will be developed carrying information on scope, time horizon and bottlenecks. On this basis suggestions for the research needs and future actions will be developed and presented.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'The optimisation of sweet taste quality' to be submitted under Fourth Framework.

assistant: **Abstract**

This proposal will co-ordinate scientific understanding of sweet taste mechanisms and apply the knowledge to the optimisation of sweet taste quality in foods. It will operate by a series of research visits, workshops and symposia, co-ordinated by Partner 1, which will harness existing knowledge and research in 10 laboratories and utilise the fund of basic knowledge available from the European Chemoreception Research Organisation (ECRO). All of the participating laboratories are members of ECRO and each, therefore, is able to seek further 'friendly' support from ECRO if and when needed. The proposal also involves five interested industrial concerns from whom support, participation and commercial resources will be available for the proposal's long term objective which is to apply sweet taste optimisation technology to commercial food products. Although many products require intense sweeteners for specific formulations (e.g. Dietetic, diabetic and tooth-friendly foods), the sweetness quality must match the ideal quality of sucrose for full consumer acceptance. Thus, a prime objective of this proposal is the improvement of sweet taste quality through the application of knowledge involving the mechanistic understanding of the action of sweeteners. This knowledge is already available from the successful conclusion of the EC-AIR project CT94-2107 'The mechanistic understanding of the sweetness response'. Achieving sweet taste optimisation will require the continued study of sweet tasting compounds available through chemical synthesis, with their potencies calculated by quantitative structure-activity relationships (Partners 1, 3 and 5), but initial behavioural understanding of these must be by non-human primates (Partner 4). Human sensory responses to optimised sweeteners in f
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Mechanisms involved in the regulation of post-golgi biosynthetic traffic by phosphoinositides' will create measurable scientific, societal and economic impact aligned with Fifth Framework.

assistant: **Impact**

In this project we will clarify the mechanisms involved in the regulation of cargo exit from the TGN to the plasma membrane by phosphoinositites such as PI(4)P and PI(4,5)P2 in polarized cells by a combination of a video microscopy and sophisticated biochemistry.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Mapping canine genes and pathways to leverage personalized treatment options' (K9GENES) under Seventh Framework.

assistant: **Objectives**

The domestic dog encompasses hundreds of genetically isolated breeds, many of which show an increased risk for certain diseases. With the canine genome sequence, an understanding of the haplotype structure and availability of disease gene mapping tools, we are now in a unique position to map canine disease genes to inform human biology and medicine. So far we have mapped monogenic traits as well as >40 loci for >10 complex traits. We now propose to map genes for key diseases using many breeds to dissect a larger number of genes underlying the specific disease. We further plan to evaluate the functional consequences of mutations and pilot personalized treatment strategies based on genetic risk. The specific aims are:1.Characterization of disease phenotypes, breed predisposition and sample acquisition. We are currently collecting samples from >20 diseases and will expand our phenotypic classification and sample collection to a larger number of breeds for some key diseases such as osteosarcoma, breast cancer, behavior and atopy or lymphocytic thyroiditis.2.Identification and functional characterization of canine disease genes and pathways. We will perform genomewide association mapping followed by targeted resequencing for mutation detection. Pathway analysis will be performed to understand the disease mechanisms mostly contributing to the disease. For select mutations, we will use state of the art molecular biology to provide detailed functional characterization of selected genes revealed by our gene discovery platform.3.Piloting canine personalized treatment strategies based on inherited risk factors.For a few diseases we will pilot personalized treatment strategies based on inherited risk factors, utilizing the genetic information gathered in aim 2. Available or novel d
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'The role of sleep in synaptic plasticity' to be submitted under Horizon 2020.

assistant: **Abstract**

Although we spend a third of our lives sleeping, the function of sleep remains mysterious. Studies considering neural networks, brain regions and behavior suggest the intriguing hypothesis that sleep is important for synaptic plasticity. However, as prior studies have conducted analyses using broad brain regions or circuit networks, the precise role of sleep in synaptic plasticity remains intensely debated. Progress in this area is hindered by the lack of a genetically-tractable system of sleep-dependent synaptic plasticity. To solve this, I developed a unique fruit fly model. It is the first model of its kind in which the cellular players comprising the synapses can be genetically labelled and manipulated. I will use this model to address a long-running controversy in the field--which form(s) of synaptic plasticity is promoted by sleep--by directly monitoring the effects of sleep on precisely identified synapses at electrophysiological and ultrastructural levels. Then, I will investigate the mechanisms underlying this process by analyzing the effects of sleep on every cellular component (pre and postsynaptic neurons and perisynaptic astrocytes) in this model at molecular and cellular levels. Emerging data suggest that astrocytes play a key role in synaptic plasticity and have further implicated these cells in regulating sleep. However, it has been difficult to directly examine the role of astrocytes in sleep-dependent synaptic plasticity, since no methodology currently exists for reproducibly manipulating local astrocytes enveloping the synapse of interest. For this, I will implement a unique tool, named G-CLAMP, and use it to assess potential glial mechanisms underlying sleep-dependent plasticity. Considered as a whole, my project will produce unique and comprehensive
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Constructing functional polyolefins through an iron catalyzed one-pot POLYmerization FUNctionalization strategy' to be submitted under Horizon Europe.

assistant: **Abstract**

We are in an era of demand for new, high-performance and sustainable plastics. The challenge is to counterbalance the actual need of society for disposable devices without compromising the sustainability of the overall production. Within the polymer field, polyolefins account for more than 50% of global plastics demand. However, their main drawback is represented by their hydrophobicity and their poor applicability in blending, adhesion and dyeing due to a lack of functional groups. In this regard, one fundamental challenge is to develop a new strategy that combines polymer synthesis and the incorporation of polar moieties into polyolefins. Within this context, POLYFUN seeks to deliver functional polyolefins by employing a single iron-based catalyst to perform two subsequent catalytic steps in a one-pot strategy. This approach, although being an important tool at the molecular level, has not yet found any application in the polymer field to access materials with intriguing and robust properties in one single process. From a scientific and technological perspective, POLYFUN intends to fabricate functionalized polymers with tunable and unique properties with an innovative approach in the field. This project is highly interdisciplinary, involving different research areas such as organic chemistry, catalysis, and material science. As such, it is envisioned that the development of this new strategy can generate breakthrough scientific papers, valuable discoveries and/or potential patents. This fellowship brings a two-fold transfer of knowledge: advanced techniques in organic chemistry to the host institution and material chemistry to the fellow. Overall, the project’s multidisciplinarity and intersectoral nature will broaden the fellow’s competencies and will place her in a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'SPEECH TRAINING FOR DEAF AND HEARING-IMPAIRED PEOPLE' (ISAEUS) under Fourth Framework.

assistant: **Objectives**

ISAEUS will develop hardware and software tools for the speech training of hearing-impaired people in French, German and Spanish, helped by the consortium's long experience in this field, as well as in automatic processing of these languages, and in foreign language teaching. Speech education and/or rehabilitation with computer-assisted techniques are often adapted to children under the guidance of a teacher. For adult people, the concept of individual training is of prime importance, especially for hearing-impaired people who have reached a reasonable oral language level, or people impaired by acquired deafness and whose speech may get worse. In this project the computer would intervene either to confirm or to warn and correct in instances of voice deterioration.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'CAPDENAC HYDRO POWER PLANT - ADVANTAGES OF AN AXIAL TURBINE WITH DOWNSTREAM BEARING IN A MODERNIZATION PROJECT', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

The project purpose is to replace an existing obsolete powerplant, consisting in several old Francis turbines, by a new axial flow inclined machine able to turbine a higher discharge at a better efficiency. The new turbine will be of the single regulated type (movable blades and fixed wicket gates). The innovative aspect will consist in the location of the turbine guide bearing which supports the runner weight. This one will be placed downstream the runner hub (instead of upstream, the common location). By this way, the design of the main turbine shaft becomes completely free and allows very interesting savings in the construction (small bearing and hollow shaft). The new plant will produce more than 8 millions of kWh per year and, for a total cost of 20 millions FF, the expected pay-back is around 8 to 9 years.INNOVATIVE TECHNOLOGY: Usually, in an axial flow turbine, the main bearing (sometimes called foot bearing), is located immediately upstream of the runner hub in order to reduce overhanging. Because of the low rotation speed, the diameter of the bearing is a consequence of the shaft diameter dimensioned to support the hydraulic torque and to permit a correct behaviour regarding the critical speeds. Therefore, when the head is sufficiently low, the bearing diameter is always oversized. The idea, in the CAPDENAC project, is to transfer the bearing downstream of the runner hub, at the extreme end of the rotating parts. This arrangement leads to several consequences. First of all, the bearing size is only calculated to support the weight of the rotating parts and its size reduces dramatically. For example in the project, the bearing diameter will be reduced from 320 mm to approximately 100 mm. This small bearing is easy to change and could be changed systematically af
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Fibrin sealant for anastomotic leaks and haemostasis' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Sealantium Medical Ltd is developing a novel product, sFilm-FS, a bio-compatible bio-absorbable, polymeric film embeddedwith lyophilized Human Fibrinogen, Human Thrombin and calcium chloride. This novel product aimed to help controllingbody fluid leakage in general surgery procedures, proposing its use as an adjunct to hemostasis and/or sealing. sFilm-FS isintended to be used for soft tissue bleeding during surgeries, when control of bleeding by standard surgical methods ofhemostasis (suture, ligature, cautery) is ineffective or impractical. sFilm-FS is also intended for use as adjunct to sealing ingastrointestinal anastomosis procedures for prevention of leakage following intestinal anastomosis.sFilm-FS is a combination product based on a degradable, bio-compatible non-permeable polymeric film that containsbiological components which serve as a glue fixing the film to its target tissue. Unlike other products which contain similarcomponents, sFilm-FS primary mode of action is based on the sealing capacity of the polymeric film. sFilm-FS was tested inrat and pig models demonstrating high safety profile and effective hemostatic and sealing capabilities. The product wasabsorbed after two weeks without any side effects allowing perfect healing of the injured tissue. The objective of the projectis to continue the development of the product to a stage which demonstrates the safety and efficacy of the product in phaseI/II human clinical trials, including GMP manufacturing upscale. sFilm–FS will make surgical procedures shorter bypreventing surgical complications, saving time, efforts and risks taken by the medical staff. sFilm-FS will also significantlyimprove the prognosis and outcome of various surgical procedures by preventing complications related to post-surgicalbleeding
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'HARMONISED EUROPEAN SOLUTIONS FOR TESTING AUTOMATED ROAD TRANSPORT', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

The HEADSTART (Harmonised European Solutions for Testing Automated Road Transport) project will define testing and validation procedures of Connected and Automated Driving (CAD) functions including its key enabling technologies (i.e. communications, cyber-security, positioning) by cross-linking of all test instances such as simulation, proving ground and real world field tests to validate safety and security performance according to the needs of key user groups (technology developers, consumer testing groups and type approval authorities).Five (5) objectives encompass the HEADSTART project: 1) Create a dynamic catalogue of existing methodologies, procedures, tools for testing, validation and certification considering multi-stakeholder requirements2) Harmonisation of existing testing and validation approaches taking into account other industries and domains3) Define and develop test, validation and certification methodologies and procedures for CAD functions building upon existing initiatives.4) Demonstrate the developed methodologies, procedures and tools through the testing of 4 CAD use cases.5) Reach consensus by creating and managing an expert network  of CAD testing to promote adoption of the project results considering multi-stakeholder needsHEADSTART brings together a large representation of stakeholders across the value chain leveraging the knowledge from European and national activities on CAD testing. The consortium and associated stakeholders will cluster the most relevant initiatives, develop the specific procedures and tools missing and harmonise the whole approach to reach a harmonised European solution for testing, validating and certifying automated road vehicles. This will be achieved through international cooperation with industry, academia and policy m
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Cost-effective technologies for wastewater treatment and waste biodegradation in agro-industries with reclamation of resources' (AGROIWATECH).

assistant: **Innovation**

Agro-industries like sugar production, potato processing, fruit and vegetable processing and breweries consume huge amount of water for process, which ends as very polluted wastewater. Development of cost-effective reclamation techniques will stimulate the usage of their important potential resources in agro-industries. The project partners are aiming to develop such techniques, to provide a direct link between wastewater treatment and their industrial water consumption. The core technology for organic pollution removal will consist of an anaerobic treatment step without energy demand, actually valuable biogas will be produced. This will be followed by development of proper biological and/or chemical post treatment to achieve water quality standards for reuse. Economics of integrated waste and water management will be implemented.