RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'FLAX AND HEMP ADVANCED FIBER BASED COMPOSITES'.

assistant: **Innovation**

Agriculture is one of the biggest sectors in Europe, representing a gross value added around EUR 148 billion, employing almost 25 million people in the EU-27(2011). However, this sector faces nowadays several challenges: competition with cheaper products from other countries, lower margins, and stringent policies, while keeping required productivity, safety and sustainability within EU. Development of a competitive and sustainable agriculture will not be possible without providing the tools to valorize its products through novel products and techniques.Nowadays, ecological concern has resulted in a renewed interest in materials derived from renewable resources, like natural fibres. Although the demand for natural fibers is growing worldwide and its price is increasing, annual plants such as jute, sisal, kenaf, flax or hemp require further development to provide novel products with improved properties.Packaging industry has a huge interest in reducing packaging materials and associated wastes, biodegradable materials have been evaluated for this application. However, the use of biodegradable films for food packaging has been strongly limited because of the poor barrier properties and weak mechanical properties shown by natural polymers. A possible strategy to increase its properties is the development of fibre based biocomposites. In TRAYSRENEW project (FP7-SME-2010, Proposal number 262269) poultry packaging materials derived from hemp and flax composites were processed and characterised. However, further efforts need to be performed to optimise project results.FLHEA will use the results from Traysrenew to provide a novel range of surface modified reinforcements. The project will focus on the upscaling and modification of micro and nanoreinforcements based in Hemp and fl
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Natrocarbonatites: are they unique, or are they key to understanding how volcanoes erupt igneous carbonate from the Earth's mantle?' to be submitted under Sixth Framework.

assistant: **Abstract**

We aim to establish whether the Oldoinyo Lengai volcano, Tanzania is unique in erupting na-rich natrocarbonatite", or is representative of other carbonatites. As the only active carbonatite volcano, Lengai has been the subject of many studies but whether it truly represents other carbonatites is key to understanding one part of the C cycle: that which brings carbonate from the Earth's mantle. With access to a unique collection of altered lengai lavas, we will construct [1] a model of subsolidus alteration in Lengai and other carbonatites, linking the various carbonatite types, and [2] a detailed analysis of the alteration, including identifying key minerals to recognise weathered natrocarbonatite in volcanic successions, sediments and soils.We will undertake a pilot study of east African soils and sediments from archaeological sites to search for evidence of carbonatite. We will ascertain whether Lengai is unique, discuss the role of na in carbonate magmas, and collaborate with soil scientists and archaeologists to apply the results to land management and reconstruction of palaeoconditions. Based at The Natural History Museum London, a world centre for carbonatite studies, and in collaboration with experts in Germany, Hungary and UK, we will undertake a meticulous and comprehensive approach involving advanced studies in mineralogy, petrology, geochemistry (including isotopes), soil science, and thermodynamic modelling.Additionally, the project will provide interdisciplinary training in petrology, soil science, modern analytical techniques and the public presentation of science to enable the candidate to become a research leader in Russia, with a return phase at St. Petersburg University. The project contributes to 3 aims of structuring the ERA: human mobility, communica
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Understanding the Role of Material Stock Patterns for the Transformation to a Sustainable Society' (2014-2020).

assistant: **Innovation**

Sustainability transformations imply fundamental changes in the societal use of biophysical resources. Current socioeconomic metabolism research traces flows of energy, materials or substances to capture resource use: input of raw materials or energy, their fate in production and consumption, and the discharge of wastes and emissions. This approach has yielded important insights into eco-efficiency and long-term drivers of resource use. But due to its focus on flows, socio-metabolic research has not yet incorporated material stocks or their services, thereby not fully realizing its analytic potential. MAT_STOCKS addresses this gap by developing a consistent typology, indicators and databases of material stocks and their services, building upon economy-wide material flow analysis. It will create a comprehensive, global, national-level, validated material stocks and services database as well as maps of material stocks from remote-sensing data. This will allow analyzing the stock/flow/service nexus and underpin highly innovative indicators of eco-efficiency overcoming limitations of current approaches which mainly relate resource use or emissions to population and GDP. New insights on stock/flow/service relations, the relevance of spatial patterns and options for decoupling will be used to create a dynamic model to assess option spaces for transformations towards sustainable metabolism. MAT_STOCKS will identify barriers and leverage points for future sustainability transformations and the SDGs, and elucidate their socio-ecological and political implications. Our preliminary analyses suggest that unravelling the stock/flow/service nexus provides a crucial missing link in socio-metabolic research because it explains why, how and where patterns of material and energy use chan
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Culture as an evolutionary force: Does song learning accelerate speciation in a bat ring species?'.

assistant: **Innovation**

Culture is highly relevant for human evolution but whether animal culture can be an evolutionary force that promotes speciation is an open and highly contested issue. While culturally induced song divergence can be correlated with increased speciation rates in songbirds, it is hard to resolve whether cultural differences are promoting speciation or vice versa. Studying ring species is a perfect solution for this problem since they illustrate divergence in space instead of time, thus allowing us to determine whether cultural differences are causes or consequences of speciation. A ring species originates from a population that expands around an uninhabitable barrier and gradually diverges until the terminal forms are reproductively isolated upon secondary contact. We will study whether culturally induced song divergence accelerates speciation in the bat Saccopteryx bilineata, the first known mammalian ring species. Cultural differences between S. bilineata populations are manifested in distinct and temporally stable song dialects which juvenile males learn from adults. First, we will study song divergence around the ring and the relative contribution of song dialects to reproductive isolation of the co-occurring terminal forms of the ring. Second, we will study potential genetic predispositions for learning specific song dialects and investigate neurogenetic mechanisms involved in mammalian song learning. Third, we will reconstruct the history, evolutionary patterns and processes of speciation in a ring using a genomic approach in S. bilineata and its sympatric sister species. This comparative approach will allow us to unravel factors involved in the rapid divergence of S. bilineata on a small spatial scale. In synthesis, we will be able to determine whether sexually sele
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Designing Democracy on ´Mars´ and ´Earth´:  Exploring Citizens´ Democratic Preferences in a Deliberative and Co-Creative Design' under Horizon Europe.

assistant: **Concept**

DDME sets up a bottom-up, co-creative and deliberative design to obtain a deeper understanding of citizens democratic preferences in two Western (Germany and United States) and one non-Western country (India). Democratic preferences contain procedural preferences for different governance modes  such as participatory, delegative, consensual or majoritarian forms of democratic governance  as well as preferences for democratic goals and values - such as equality or social justice. Based on input and feedback from democratic theorists, DDME explores how citizens imagine ideal democracy (on Mars) and mend real democracy (i.e., how they would reform the political systems they live in (on Earth)) when they had the chance to deliberate, i.e. to weigh reasons regarding the pros and cons of the various conceptions and schemes of democracy in a dialogical setting with their fellow citizens. The deliberative field experiments will comprise 600-900 representative or maximally diverse citizens and will be run on a hybrid platform combining synchronous and asynchronous modes of interaction. DDME analyses which factors drive different democratic preferences of citizens in the three different countries and which principles and arguments play a role in the opinion and preference formation of citizens democratic preferences (with a specific eye on opinion and preference change). The project is the first to delegate democratic designing to citizens adopting a systematic and global approach where citizens together with democratic theorists think through advanced theoretical inputs and think creatively about optimal democratic designs.


**Keywords:** Deliberation, Democratic Theory, Public Opinion, Citizen Perspectives
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'An Advanced Structural Integrity System for Air Transport Composites using NDT Evaluation and Damage Tolerance Methods' (TRACE-IT), addressing dissemination and exploitation.

assistant: **Impact**

There is a huge industrial and innovative need for more efficient and reliable damage inspection as well as for reducing the time and cost for aircraft infrastructure maintenance and especially C and D Checks without compromising the safety of passengers and goods transported. This reduction would increase the value for money for the European aerospace industries. Moreover, airline companies will be able to reduce their tickets’ prices and make air travel more affordable to European citizens. Last but not least, this reduction can potentially release new investments and funds to explore aircraft innovative designs and technologies. For these reasons, there is an urgent need for improving structural maintenance efficiency that will ensure not only the safe air transport of European citizens, goods and military operations but will also promote the sustainable growth of the fastest mean of transport in a tough economic era. The TRACE-IT project is focused upon the development of an innovative inspection system, with automated and manual capabilities, for any type of composite aircraft structures. The structural integrity system is comprised by two parts: a qualified PA method attached to a mobile manipulating system, and a DT (Damage Tolerance) assessment technique processed on a computer. The results from the PA technique will be used as inputs to perform a DT numerical analysis for the inspected component. Eventually, the results from the PA technique as well as the results from the DT analysis will be available, to the inspector, in a simple Graphical User Interface (GUI). Consequently, an average skilled inspector will be able to take more appropriate and cost efficient maintenance actions (e.g. component repair or complete substitution) than today’s inspection procedu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Seventh Framework proposal for the project 'GENETIC, BEHAVIOURAL, AND DEMOGRAPHIC CONSEQUENCES OF LONG-TERM HYBRIDIZATION IN SAVANNA BABOONS'.

assistant: **Objectives**

The process and consequences of hybridization are of interest to evolutionary biologists because of the importance of hybridization in understanding reproductive isolation, speciation, and the influence of introgression on population genetic structure. Although many instances of naturally occurring hybridization in primates have now been documented, we still lack a holistic understanding of how hybridization impacts individual life-histories in the short term, and population and species evolution in the long term. The goal of the proposed project is to address this gap by gaining a detailed understanding of the genetic, behavioural, and demographic consequences of hybridization in the well-studied wild Amboseli baboon population in particular and across the boundary of the southern Kenyan baboon hybrid zone as a whole. To properly realize this project I will compute long-term data on life-histories, behaviour, and mate choice already available on one of the best known wild primate populations and I will combine these data with environmental data collected through GIS analyses and with genetic data collected non-invasively from over a thousand of individuals (around 730 have already been collected) located throughout the yellow-anubis hybrid zone. The originality of this project lies in the investigation of the effects of hybridization on multiple scales: the individual baboon (effects of hybridity on individual life-history traits), the population (population genetic structure), and the meta-population (genetic differentiations between baboon populations). The results of this research will serve as a model for how hybridization can influence the population dynamics and evolution of primate species.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Pharmaco-modulation of epithelia for induction of antimicrobial peptide expression: a disruptive approach to fight antibiotic resistance' (MaxImmun).

assistant: **Concept**

The MaxImmun project aims at preventing and treating infections, and situations of conflict between the host and its microbiota, by developing a disruptive technology based on molecules that boost antimicrobial peptides (AMP) of the innate immune system. To face the problem of antibiotic resistance, this high-potential technology may be relevant both in situations of endemic infections in the developing world, and infectious or inflammatory pathologies in industrialized countries. Our objective is to establish the proof-of-concept that among a series of hit molecules identified for their capacity to promote AMPs, a small subgroup may qualify to lead molecules that can then be pushed into the late phases of the R&D pipeline, with the perspective of a phase I clinical trial. To achieve this transition, our project will range from the comprehension of microbial mechanisms leading to antibiotic resistance, to the comprehension of AMP regulations, the identification of molecules and their optimization by medicinal chemistry, and the characterization and evaluation of their protective efficacy in pre-clinical validation models. Thus, we expect to develop innovative molecules as future antimicrobial drug candidates.


**Keywords:** Therapeutic innovation, antimicrobial resistance, antimicrobial peptides, innate immunity, one health, molecule screening, medicinal chemistry, pre-clinical models
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Model based and qualitative reasoning systems network' will create measurable scientific, societal and economic impact aligned with Fourth Framework.

assistant: **Impact**

Objectives:Model based Reasoning is the symbolic processing of an explicit representation of the internal workings of a system in order to predict, simulate and explain the resultant behaviour of the system from the structure, causality and behaviour of its components. Qualitative models aim to capture the fundamental aspects of a system or mechanism, while suppressing much of the detail. Methods such as abstraction and approximation are often used to build models based on symbolic rather than numeric quantity spaces.This Network aims to provide a long-term framework for research integration and co-operation that will- co-ordinate European research in MB & QR systems, and - promote technology transfer into industry. It is intended that the network should be open to all those who can contribute to technological progress in MB & QR systems.Activities:- Aid the transfer of MB & QR systems technology to industrial applications - Co-ordinate European MB & QR systems research and initiate co-operative projects- Increase understanding and awareness of the key topics in MB & QR systems- Organise information about industrial applications of MB & QR systems- Survey the field and identify opportunities and target applicationsActivity areas:Research Fields - Within the area of model and qualitative reasoning systems we are including most forms of model-based reasoning and qualitative simulation, including: Functional and causal modelling; qualitative modelling; modelling ontologies; abstraction, aggregation and approximation; integration of mixed models; qualitative spatial modelling, kinematics and dynamics.Application domains - The technology has a wide range of applications in many domains, including: Process modelling and simulation; design, configuration and planning; vision a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'An Activity-based Protein Profiling-supported Protein Therapeutic Drug discovery platform for the development of innovative anti-cancer therapies based on Lin28 inhibition', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Cancer remains one of the most prevalent diseases worldwide and new therapeutic targets are highly sought. The oncogenic triangle LIN28/HMGA2/IGF2BP1 is a self-promoting pro-tumorigenic group of proteins with relevant roles in many cancers that antagonize the let-7 family of miRNAs, which possess anti-tumorigenic roles.Activity-based protein profiling applied to the measurement of cysteine reactivity profiles has been efficiently used to profile the landscape of ligandable cysteines in a given phenotype, which in turn has allowed the discovery of novel therapeutic targets in relevant disease phenotypes and the pharmacological modulation of targets previously described as undruggable.Our approach will characterize the influence of the LIN28/HMGA2/IGF2BP1 proteins in the cellular landscape of ligandable cysteines, focusing on liver and ovarian cancer. Additional protein interacting partners to the oncogenic triangle will be identified and validated as novel anti-tumor targets. Variations in the probes used will allow the established methodology to be adapted to other entities like serine hydrolases, well known players in cancer and metastasis, or sulfenic acids, oxidized cysteines known to take part in redox control of the cellular environment.Cysteine labeling chemistries and protein engineering will be used to weaponize LIN28/HMGA2/IGF2BP1 and their protein interactors against the oncogenic triangle as “protein drugs” via proximity-enabled reactive therapeutics, where reactive aminoacids are introduced in a native protein structure to allow a transient non-covalent interaction to be stabilized by formation of a permanent covalent bond. This approach is at the frontline of novel therapeutic methodologies and its application will restore the levels and function of let-7 m