RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Proactive Understanding of Regulated and Emerging contaminants in novel FOODs in Europe' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

The EU market for novel foods is expanding rapidly, with current products including novel plant-based alternatives, edible insects, mycoproteins, 3D-printed foods, algae-based foods, and edible packaging. Looking ahead, more novel foods are expected to enter the EU market, such as cultivated meat, single-cell proteins, and precision-fermentation dairy proteins.The European Food Safety Authority (EFSA) assesses certain contaminants in novel foods under Regulation (EU) 2015/2283, e.g., persistent organic pollutants (POPs), per- and polyfluoroalkyl substances (PFAS), and potentially toxic elements (PTEs). However, comprehensive studies across multiple novel foods and broader range of regulated and emerging contaminants (RECs) are lacking in Europe. As the EU is preparing for the market entry of more novel foods, there is a narrow window of opportunity to ensure food safety.Overall, the current knowledge of RECs in novel foods remains scarce. The 24-month PUREFOOD project aims to promote more equitable and effective regulation of food safety across Europe by screening a broad range of RECs in novel foods that are already approved or expected in the EU. To achieve this goal, PUREFOOD will comprise three research work packages (WPs): WP1 will collect up-to-date data on the import, production, and consumption of novel foods in the EU; WP2 will focus on sampling and analysing both existing and emerging novel foods in the EU, for a broad range of RECs, e.g., brominated flame retardants (BFRs), organophosphate esters (OPEs), plasticisers, currently used pesticides (CUPs), chlorinated paraffins (CPs), PFAS, PTEs, and microplastics (MPs); WP3 will identify factors influencing novel food contamination and evaluate associated human health risks.PUREFOOD will expand my analytical capa
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Acceleration Towards LEO Automatic Space Safety' (ATLAS2), addressing dissemination and exploitation.

assistant: **Impact**

The ATLAS project aims at developing the first service of Space Safety. Based on a network of 7 radars deployed around the world with a new design for scanning and tracking, capable to detect debris down to centimetric size, and through fusing data from its network and other sources, Look Up Space aims at extending the lifetime of satellites through collision avoidance and decreased number of collision avoidance manoeuvres of satellites. This service will be applicable to small satellite fleets as well as to whole satellite constellations. This will provide the EU with the first sovereign solution for space safety, dedicated to coordinating all stakeholders and automatising processes.


**Keywords:** space safety, satellites, collision avoidance, space situationnal awareness, space traffic management
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Primary bone cancer scaffolds as controlled release non-viral gene delivery platforms' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

Primary bone cancers are aggressive malignancies that characteristically arise during childhood/adolescence. Current treatment involves a multidimensional approach of surgery and chemotherapy but response to therapy can be poor-about 30% of primary bone cancer patients die within 5 years. Despite treatment with various chemotherapy regimens in the past 20 years, survival rates have notimproved and no efficacious targeted therapies have been developed. Bone tumours also often colonise large expanses of bone making it difficult to repair itself, thus resulting in a deleterious effect on patient life quality. Therefore, aligning bone tumour therapy and bone regeneration are highly challenging in the clinic. Building on my experience in this area, I propose a frontier technology to progress beyond state-of-the-art; PANACEA describes the engineering of a novel bi-functional biomaterial platform as a new strategy for bone tumour therapy. PANACEA will conquer the issues of current biomaterials approaches by utilising advances in bone tissue engineering to promote more timely bone production. A collagen nanohydroxyapatite based scaffold containing reduced grapheneoxide will be developed with pore architecture, mechanical properties and bioactive composition tailored to regenerate bone. Importantly, reduced graphene oxide is suitable for photothermal treatment of cancer cells and promotes bone repair. Utilising the expertise of the applicant on internationally recognised innovative research on scaffold-mediated gene delivery, this system will befurther functionalised for the controlled ultrasonic on-demand non-viral delivery of microRNAs to ablate cancer cell growth and direct host stem cells to regenerate stable bone at the tumour location in a timely manner. The proposed PANAC
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'PHYS@IHP CNRS UMS839' (2002-2006) under Sixth Framework.

assistant: **Objectives**

The Institut Henri-Poincare is a Research Center devoted to mathematics and theoretical physics. Since 1994 it has hosted international thematic research programs, which are organized at the Emile Borel Centre. The training of young scientists is one of t he essential missions of the centre. The fact that the programmes are run on a quarterly basis makes it ideally suited for that purpose. During their three months stay the students attend a series of doctoral courses organized in a progressive and coherent way that are given by some of the world leading experts in their research area.The list of coming programmes in physics clearly demonstrates our will to promote interdisciplinary research of top level. A-January 2006-April 2006: quantum information, computation and complexity. B-September 2006-December 2006: general relativity, astrophysics and cosmology. C-May 2007 - July 2007: quantum gases.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'From sea-bed to test-bed: harvesting the potential of marine microbes for industrial biotechnology' (SEABIOTECH).

assistant: **Innovation**

SeaBioTech is a 48-month project designed and driven by SMEs to create innovative marine biodiscovery pipelines as a means to convert the potential of marine biotechnology into novel industrial products for the pharmaceutical (human and aquaculture), cosmetic, functional food and industrial chemistry sectors. SeaBioTech will reduce barriers to successful industrial exploitation of marine biodiversity for companies more accustomed to ‘terrestrial’ biotechnology. SeaBioTech directly addresses five key challenges to remove bottlenecks in the marine biodiscovery pipeline, leading to (1) improvements in the quality of marine resources available for biotechnological exploitation, (2) improvement in technical aspects of the biodiscovery pipeline to shorten time to market, and (3) developing sustainable modes of supply of raw materials for industry. The two last challenges centre on enabling activities to enhance the marine biodiscovery process: first, clarification of legal aspects to facilitate access to marine resources, their sustainable use, and their secure exploitation; second, to create an improved framework for access to marine biotechnology data and research materials. To achieve its goals, SeaBioTech brings together complementary and world-leading experts, integrating biology, genomics, natural product chemistry, bioactivity testing, industrial bioprocessing, legal aspects, market analysis and knowledge exchange. The expertise assembled within the consortium reflects the industry-defined needs, from the SME partners’ initial definition of market and product opportunities to their ultimate proof-of-concept demonstration activities. SeaBioTech will have significant impact on research and technology, on innovation, on European competitiveness and on economic growth. It
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Integrating the activities of SUMO in gene expression, inflammation and cancer' in the context of a Seventh Framework call.

assistant: **Objectives**

Sumoylation of proteins has emerged as a central regulatory mechanism influencing a wide range of cellular processes and is notably a key pathway facilitating cellular response to stress. Gene expression appears to be particularly regulated by sumoylation as many known SUMO substrates are transcription factors and cofactors. Moreover, key chromatin proteins, including the core histones, figure among the SUMO targets. The emerging paradigm for the proposed work is that sumoylation controls multiple aspects of chromatin structure and that sumoylated proteins are principal and instructive components of a dynamic chromatin scaffold that can respond to external cues. According to this view, sumoylation is expected to impact both global and specific transcriptional programs thereby affecting constitutive and inducible gene expression.The goal of this project is to define the role of sumoylation-mediated gene control in stress response and to analyze the impact of dysregulation of this pathway in inflammation and cancer with a primary focus on the intestinal tract. Our specific aims are to 1) Identify stress-regulated molecular players of the SUMO pathway, 2) Define the genome-wide organization of the SUMO chromatin landscape and its plasticity upon stress, 3) Probe the role of sumoylation in normal and pathological inflammatory response with an emphasis on acute and chronic colitis, 4) Explore the possible implication of the SUMO pathway in colon cancer.This project is supported by a wealth of preliminary data based on genomic approaches and mouse models for partial or complete loss of sumoylation. We expect our study to bring innovative concepts on sumoylation’s role in normal and disease states. Novel regulators of sumoylation will be identified, unsuspected transcriptional
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Functional protein dynamics studied  by solution- and solid-state NMR spectroscopy' (PROTDYN2FUNCTION), addressing dissemination and exploitation.

assistant: **Impact**

Proteins are highly flexible objects that perform their functions by sampling a wide range of conformations. The characterization of such motions is, therefore, crucial to establish the link between protein structure and function. In this project we will use advanced nuclear magnetic resonance in solution state and solid state to characterize functionally important motions in two challenging classes of proteins.The first target of these studies will be a large molecular chaperone of close to 1MDa in size. Conformational changes and dynamics are a prerequisite for the function of this assembly, as it binds, encloses and folds unfolded substrate proteins. Atomic-resolution structures of such large objects frozen in their crystal lattice do not provide access to dynamic information nor insight into the folding process itself. Here, we will exploit the complementary advantages of solid- and solution-state NMR spectroscopy to probe the dynamics, allostery and binding in a ≈1MDa object. Furthermore, we will study how the chaperone cage influences folding, by observing in real time and at atomic resolution how substrate proteins achieve their native fold inside and outside this large molecular edifice.We will furthermore study the mechanism of substrate translocation across membranes by characterizing structure, interactions and dynamics in a solute carrier protein. The dynamics of integral membrane proteins is currently poorly understood. This relates to the need to address membrane protein dynamics in an environment that closely resembles the native membrane. NMR techniques on proteoliposomes as well as nanodiscs are uniquely suited to get insight into native dynamics. We will use such techniques to relate the process of substrate translocation to inherent protein dynamics o
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Ocean Energy Forum Support' (OEFS).

assistant: **Innovation**

The OEFS project strengthens and professionalizes the sectoral SET Plan stakeholder forum for ocean energy. It establishes a clear governance model, standard methods for collecting and validating evidence, and an open digital backbone for data, roadmaps, and peer review. Through an end-to-end “stakeholder-to-policy” workflow—policy labs, structured consultations, and transparent quality assurance—the action turns inputs from industry, research, authorities, and civil society into comparable, reusable outputs. Activities span the whole value chain and countries in scope, with social sciences and humanities embedded to address skills, inclusion, and just-transition needs.Impact focuses on making policy measurable, investable, and socially grounded. The action will deliver research and innovation roadmaps, barrier analyses, market and funding-needs assessments, and plain-language briefs, formatted for ingestion by SETIS and CETO. Evidence will inform NECPs and national strategies, help streamline permitting, and surface bankable opportunities for regions and SMEs. The project supports the European Green Deal and the Net-Zero Industry Act by improving coordination across Member States and widening participation, with progress tracked through KPIs, quarterly dashboards, and open repositories.The consortium consists of ACER (Spain), APREN (Portugal), and ENA (Greece). ACER and APREN bring sector networks and convening power with developers, ports, and supply-chain SMEs. ENA leads EU-level communication, digital tools, and policy engagement, ensuring visible and usable results across countries. The partners run the forum, co-produce evidence with experts and public authorities, and deliver targeted outreach at EU and national levels, supported by an independent advisory setup
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Micro fabrication production technology for MEMS on new emerging smart textiles/flexibles' to be submitted under Seventh Framework.

assistant: **Abstract**

This proposal concerns flexible materials in the form of high added value smart fabrics/textiles which are able to sense stimuli and react or adapt to them in a predetermined way. The challenge for the European textile industries is to add advanced functions to textiles and the recent progress of new technologies such as electronic inks provide an opportunity for a breakthrough by incorporating MEMS on flexible textiles/fabrics. The project will exploit microfabrication to produce, using custom printing processes, active functions cost efficiently. We propose to develop fundamental micro fabrication production technologies for MEMS on fabrics/textiles using flagship demonstrator applications. This will result in a cheap, easy to design, flexible, rapid, way to manufacture multifunction smart textiles/garments for a large set of multi-sectorial applications. The processes will be based on thick film printing and sacrificial etching for the MEMS structures. Subsequent inkjet printing will be used to deposit thinner structures on the thick film printed layers incorporating for example active nanoparticles to add further functionality. These printing processes have many benefits including low-cost, repeatability, flexibility, suitability for high throughput production, relatively inexpensive equipment, short development time and the capability of depositing a wide range of materials. All the novel printed inks will be electrically activated sensors and actuators and we will use standard electronic devices for power supply/storage, signal processing and communications offering low price and mass production. The project will undertake a number of initial demonstrators of the underlying basic technology. These will be based on: light emission, cooling/heating, anti-static effe
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'An EEG calibration toolkit for monitoring rehabilitation of stroke patients.'.

assistant: **Innovation**

An EEG calibration toolkit for monitoring rehabilitation of stroke patientsEEG records electric potential differences from electrodes attached to the human skin. Since it is a brain imaging technique that provides a direct measure of neural activity, it is an ideal device to monitor stroke rehabilitation. For instance, the amplitude of an EEG response to a fixed external stimulus on the wrist could act as a biomarker quantifying the number of active cells in the primary somatosensory cortex. In this way, an EEG system could work as a simple monitoring device rendering direct feedback to healthcare workers on the success of the applied therapeutic strategy. This would greatly help to select the most optimal therapy for the individual patient.However, with the current state of the art a direct comparison between EEG amplitudes of different subjects is not possible because these amplitudes are strongly affected by inter individual skull variations. In this PoC project a calibration step is proposed to reduce these influences on the EEG biomarker. We will develop a software toolkit, allowing to execute the required calibration step with a minimum of patient burden. We foresee that the prototype delivered by the end of the project can be developed into a commercial accessory EEG software device that can be provided to end users for relatively small add-on price. Best practices of EEG calibration will be disseminated by publications, presentations at conferences, a special workshop and business development activities.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Intelligent Wearable System for Enhanced Personalized Gait Rehabilitation' (GaitREHub).

assistant: **Innovation**

One common consequence of specific medical conditions such as stroke or other brain injuries, and certain operations, is the need for post event rehabilitation. In many cases, the inability to walk properly requires professionally monitored gait rehabilitation. Gait rehabilitation is important to restore the gait performance of mobility impaired patients and gait training frequency represents a key factor for effective rehabilitation. GaitREHub aims to develop an effective, comprehensive approach to providing targeted home-based gait rehabilitation, by integrating cutting-edge technologies, from the areas of (1) computer-based design and modelling of customized smart insole/socks, (2) wearable sensors and flexible embedded electronics realization, (3) home assistive robots, data analytics and artificial intelligence algorithms development as well as user-friendly software tool for gait rehabilitation, and (4) pre-clinical validation of the developed holistic, integrated and interactive system (our “REHub”). The GaitREHub consortium consists of international recognized institutions and organizations, 4 from academic and 3 from industrial sector, from Belgium, Italy, Greece, Serbia, Chile and Thailand. GaitREHub will facilitate the exchange of knowledge, skills and competencies throughout 199 person-months of carefully planned secondments, promoting international and interdisciplinary collaboration and disseminating the project results to all stakeholders. This interdisciplinary and inter-sectorial project offers an excellent research and innovation environment for the personal and professional growth of the seconded staff members. The outputs of GaitREHub will effectively enhance the personalized rehabilitation of neurologically injured patients and any other patient in