RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Analysis of and Responses to Extremist Narratives' (ARENAS), addressing dissemination and exploitation.

assistant: **Impact**

Social protest movements, the Covid-19 crisis and the war in Ukraine have triggered increased polarization of debates. They have challenged European democracies and thus fostered extreme narratives, with strong and numerous consequences for citizens, politics, and the democratic exercise. The ARENAS consortium focuses on the narratives as crucial nexuses, because “the battle of stories, not the debate on issues” (Cornog 2014) can determine the way that citizens react to political events. A strong antagonism is constructed between extremist and mainstream narratives, which is evident if we compare the narratives on the on-going war in Ukraine. Extremist narratives always reflect the complex intersection of spatial and temporal context where the narratives are constructed, circulated, consumed, and reproduced. They are characterized by their reliance on pathos and emotions, as well as the importance of violence in them: they tend to proliferate in historical periods characterized by social turmoil, and construct an alternative reality and promote negative emotions and behavioral patterns that run against mainstream and official narratives. In social media and through the connections between social and “traditional” media, extremist narratives are naturalized and have an impact on mainstream narratives. ARENAS will provide concrete responses to the consequences of these extremist narratives by: i) measuring and mapping the spread of extremist narratives; ii) defining remediation actions for individuals and groups affected by extremist narratives; iii) providing educational and institutional propositions to anticipate future challenges in terms of the construction and circulation of extremist narratives; and iv) identifying multi-level policy recommendations to help counter
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Silicon-Carbide-Fiber Pilot-production in Europe' (SPE), addressing dissemination and exploitation.

assistant: **Impact**

BJS Ceramics GmbH (BJS), Gersthofen, Germany, is Europe’s only Silicon Carbide (SiC) Fiber developer and producer inspe. SiC fibers are the key raw material for SiC Fiber reinforced Silicon Carbide (SiC/SiC) composites that are technicallyindispensable in turbines for aircraft and energy generation to reach a step-change in energy-efficiency due to theiroutstanding heat resistance (260°C higher than that of the nickel-based superalloys) and light weight. Only turbines with SiC/SiC components meet the CO2-, NOx- and noise emission reduction targets established by the Advisory Council for AviationResearch in Europe (ACARE), respectively those established by the Federal Aviation Authority (FAA) in the United States.Aviation contributes significantly to the global emissions of CO2 and NOx thereby aggravating the climate change. If theaviation sector was a country, it would rank 7th in the global ranking! Aviation is growing above average, expected to doubleby 2035. That is why emissions from aviation need a significant reduction.SiC Fibers respectively SiC/SiC composites are key to achieve these emission reductions, but the global supply chain forSiC fibers is fragile due to SiC fibers, their raw materials and SiC/SiC composites being dual use, and subject to exportcontrol. To-date, there are only 2 SiC fiber producers in Japan, 1 SiC fiber plant is under construction in the US in closecooperation with the US Air Force – leaving European turbine producers with a risky or no supply chain. In order for Europeto be independent in SiC Fibers and SiC/SiC composites, it is mandatory to build up a European SiC fiber production. BJSwith its patented SiC fiber technology will reach TRL4/5 by end 2018. In 2019, the first European SiC fiber line in Bayreuthwill start production. BJS w
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'NeuroVU: Real-time Sensing in Microfluidic Models of the Neurovascular Unit' (NeuroVU), addressing dissemination and exploitation.

assistant: **Impact**

Disorders of the central nervous system are one of the grand health challenges of this century. Therapeutic development, however, remains limited by poor understanding of the brain, including of the neurovascular unit (NVU). The NVU acts as the gatekeeper between blood and brain for metabolites, disease agents, as well as drugs. Much research has relied on animals or simple cell models that recapitulate neither the cellular ensemble nor the environment of the NVU. Emerging Organ-on-Chip microsystems promise to overcome these limitations, but to date fall short on the relevance of cells used and the lack of continuous monitoring capabilities for chemical markers, metabolic conversions, and pharmacodynamics.My objective in this project is to develop the first NVU Organ-on-Chip integrating human-normal cells as well as biophysical and biochemical sensors for real-time monitoring, termed NeuroVU. I propose to rely on primary and induced pluripotent stem cells, which can achieve in-vivo-like properties, and off-stoichiometry thiol-ene-epoxies (OSTE+) as the enabling technologies. OSTE+ is a versatile polymer uniquely suited to supersede the prevalent polydimethylsiloxane/glass paradigm for the innovative system integration approaches needed here. I will first characterize and optimize it for compatibility with biological and sensor components. I will build on these component insights with microsystems integration to develop NeuroVUs featuring co-culture of NVU-normal cells, continuous monitoring of relevant ions & metabolites in addition to trans-endothelial electrical resistance, and tissue-like hydrogel structures. I will leverage collaborations with resident experts in materials and biology as well as my own strong background in microsystems integration to realize this hi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Coherent Optics Everywhere: a New Dawn for Photonic Networks', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

The widespread adoption of the Internet and its influence on our daily life is unquestioned. Global Zettabyte traffic has rendered photonics as indispensable for the communication infrastructure. While direct signal detection has been dismissed in radio communications decades ago, it prevails in short- and medium-reach optics in virtue of its simplicity. In such an environment photonics can only rely on incremental improvements, whereas it desperately seeks for disruptive concepts.COYOTE envisions a novel coherent homodyne transceiver concept for analogue signals and access to higher-order formats with efficiencies of 10 bits/symbol. On top of this, high-fidelity transport of multi-band 5G radio signals in the millimetre-wave range up to 100 GHz will be enabled by analogue coherent photonics while mitigating energy-hungry digital signal processing. COYOTE takes one more leap and dares the contradictory full-duplex data transmission in virtue of its novel reception engine to ultimately guarantee a lean solution with greatly simplified yet flexible “hardware”. The key asset of COYOTE’s coherent engine will be a locked laser with improved coherence characteristics together with a flexible modulator-detector element, which is capable to emulate direct-detection systems in a transparent way while giving birth to novel networking concepts. Exploration of the 3D Stokes and 2D quadrature spaces through a segmented receiver architecture will boost the spectral efficiency to >10 bits/s/Hz.It is the lean and yet efficient coherent transceiver methodology of COYOTE that will remove the currently existing boundary between direct-detection and coherent systems in the midst of network reaches. By coherently “reviving” these telecom segments of integrated wireline-wireless access netwo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Attosecond dynamics of ion-biomolecule collisions by nuclear and electron wavepackets' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

The advent of ultrashort pulses produced by free-electron lasers and high harmonic generation has opened up the way to a new chemistry at the femto and attosecond time scales. Processes such as laser induced ionisation and dissociation can now be monitored in real time and can be used to control chemical reactions. However, the dynamics of charge transfer (CT) processes taking place in a collision have never been investigated. ATTONEW aims at analyzing the mechanism of CT during an ion-biomolecule collision in real time for the first time. Novel time-dependent (TD) wavepacket propagation methods will be developed to follow the attosecond nuclear and electron motion involved in the collision. Moreover, we will also explore the possibility of controlling the reaction by preparing electronic wavepackets in the Uracil molecule. The methodology will be applied to the interactions between carbon ions, C2+ and C4+, with the RNA base Uracil. CT in ion-biomolecule systems is interesting since it is responsible for cancer disease and controlled cell killing used in radiotherapy. Such complex systems demand detailed knowledge of the potentials energies and non-adiabatic couplings between the states involved in the process; these will be obtained with high level ab initio multiconfigurational methods. Due to the high energies involved in the collision (keV), the proposed dynamical calculations are memory extensive requiring algorithm parallelization. We propose two different TD scenarios in which wavepackets will be simulated first, in one dimension (assuming a single attack direction), and second, in two dimensions (considering a planar and a perpendicular attack). Combining these two attacks, we will obtain anisotropic features of the global three-dimensional collision process, d
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Discovering how T6SS effectors are deployed in the recipient cytoplasm' (IMCross).

assistant: **Innovation**

Interbacterial competition is a key driver of the emergence of new bacterial strains. A widely used strategy during interbacterial competition is delivering toxins into competitors’ cytoplasm, where they target conserved components. The type VI secretion system (T6SS), a machine that delivers toxic effectors into neighboring cells, is a major player in interbacterial competitions. It fires an effector-loaded tube that penetrates the recipient cell envelope. Although many T6SS effectors target the competitors’ cytoplasm, it is not known whether they are directly deployed there or rather deployed in the periplasm and then transported into the cytoplasm. We have recently identified several domains within modular T6SS effectors that are fused specifically to cytoplasm-targeting toxic domains. The new domains are required for competitor intoxication during competition but not for T6SS-mediated secretion of the effectors. Therefore, we hypothesize that T6SS effectors are first deployed in the periplasm, where specialized domains such as these re-localize cytoplasm-targeting effectors into the recipient’s cytoplasm. In IMCross, we will leverage our unique expertise in identifying and characterizing novel domains within effectors to go beyond the state-of-the-art and determine how cytoplasm-targeting T6SS effectors reach their target. We will (1) reveal the initial site of T6SS effector deployment, (2) identify effector domains responsible for transport across the recipient inner membrane and determine whether they employ receptors in the process, and (3) establish a pipeline to discover re-localization domains and cytoplasm-targeting toxic domains in T6SS effectors. The discovery of specialized T6SS effector re-localization domains will revolutionize our understanding of effec
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'The prevention of pelvic inflammatory disease with particular respect to screening for Chlamydia Trachomatis' (1994-1998).

assistant: **Innovation**

Objectives: - To assess effective methods of screening for chlamydia in women - To study the prevalence of chlamydial infection in Europe - To assess the costs and benefits of screening for chlamydia in women - To devise strategies to reduce the prevalence and sequelae of chlamydial infection - To assess the long term sequelae of PID, particularly ectopic pregnancy and infertility - To enhance public awareness of chlamydial infection and PID in womenBrief description:Pelvic inflammatory disease (PID) is the most serious and costly sexually transmitted disease that effects women. Infection is likely to result in chronic ill-health, infertility and ectopic pregnancy. Chlamydia Trachomatis is the major cause of PID and is the most common sexually transmitted bacterium in the developed world. There is evidence that screening programmes for chlamydia can be cost effective and likely to result in a reduction in the incidence of PID. Recent advances in screening technology indicate that widespread screening among men and women may be both feasible and acceptable. However the efficacy and cost effectiveness of such strategies need to be assessed.It is proposed to develop and assess effective methods of screening for lower tract infection in women, as well as compare prevalence of chlamydial infection in both men and women in different European settings. An important issue will be the critical study of the cost effectiveness of screening for chlamydia. It is intended to devise and test strategies to reduce the prevalence and sequelae of chlamydial infection while developing robust means of measuring the long term sequelae. Thus our studies have the major aim of introducing effective preventive measures for PID, while at the same time raising the level of awareness of this major
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Process industries diagnostic experiments' (PRIDE).

assistant: **Innovation**

Process supervision is increasingly important as a major factor affecting the efficiency and therefore the competitiveness of the European process industry which account for nearly half of the European manufacturing sector. Process supervision is also very important from the point of view of equipment manufacturers, including software specialists since the equipment for process supervision represent a market in excess of 15 billion ECU world-wide.Knowledge Based Systems (KBS), including first generation rule-based expert systems, have demonstrated great potential for many tasks related to process supervision. Malfunction diagnosis, which has relied almost entirely on human expertise until a few years ago, is probably the most critical task among them. Still, the spread of knowledge based technology in process applications is limited to a number of key cases of high economic importance due to the high cost of development, adaptation and configuration.The strategic objective of PRIDE is therefore to contribute to improving the performance of the European Process Industries, through establishing the basis for a broader application of Model-Based Diagnosis (MBD). PRIDE will validate the benefits of MBD on selected industrial applications including chemicals manufacture, energy generation, water treatment, gas pumping stations and nuclear fuel production. Furthermore PRIDE will contribute to methodological guidelines to enable rapid and relatively cheap applications in other companies, on other plants, and in other sectors of the process industries.The PRIDE consortium is exceptionally well suited to achieve these objective as it combines key European expertise in model-based technology (CISE, KCL and Heriot-Watt University) with several large process industries operating in
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Ultrafast atomic and molecular physics at x-ray free electron lasers' (2007-2013) under Seventh Framework.

assistant: **Objectives**

The ultrafast interaction of x rays with matter is a new field that is enabled experimentally by novel light sources like free-electron lasers and is essentially unexplored theoretically. Exciting new possibilities open up in many areas of science for which the theoretical basis for their understanding needs to be established. This is the goal of the presented proposal with respect to fundamental questions in atomic, molecular, and optical physics. Proceeding from the basics to more complex scenarios, I will study the fundamental nonlinearities in the interaction of x rays with matter that manifest in multiphoton and multielectron processes. First, I will study the absorption of x rays by molecules, including multiple core hole formation and decay, and few-x-ray-photon absorption. Second, I will combine x rays with a high-intensity optical laser, a two-color problem. Specifically, I will establish quantum optics for x rays by “watching” electromagnetically induced transparency for x rays in real time with ultrashort x-ray pulses. Then, I will examine the manipulation of the high harmonic generation process with x rays and explore its potential for providing light with unprecedented traits at such energies; notably, the generation of attosecond x-ray pulses may become feasible.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Responsible prediction of gene expression: mitigating genetic risk profiling' (PredicGenX).

assistant: **Concept**

Environmental factors are crucial to physical and mental healththey impact even the expression of our DNA. The study of epigenetics provides better understanding of gene-environment interaction. Environmental influence can come from outside and inside the organism but one environmental factor that is typically overlooked is peoples knowledge production and beliefs. PredicGenX responds to the scientific worry that predictions about genes are likely to be reflexive i.e., they impact the eventual outcome. Scholars have raised concerns that beliefs about genetic information affects genetic risk to match that informationa so-called self-fulfilling prophecy not unlike the placebo and nocebo effects. Studies showed that receiving ones genetic risk profile can change physiology independent of actual genetic risk. Moreover, the current trend to focus on risk, biomarkers, and early diagnostics produces 'knowledge' which is inevitably based on undetermined information, given that gene expression is not fixed. Asserting genetic information as determined when the assertion itself has potential impact on genetic expression is especially alarming considering the popularity of direct-to-consumer genetic testing and precision medicine. Understanding the direct impact of genetic predictions on gene-expression, its vulnerability to feedback loops, and their moral implications is crucial, urgent, yet currently lacking. With this project, I aim to fill that knowledge gap. Through qualitative fieldwork and philosophical analysis, I will theorise the different ways in which reflexive (epi)genetic prediction manifests andwhile detailing a descriptive account of the different modelsoffer an analysis of the epistemic and ethical implications of their reflexivity on research and practice, and the