RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Brain-Inspired Organic Modular Lab-on-a-Chip for Cell Classification' to be submitted under Horizon 2020.

assistant: **Abstract**

Brain-inspired (neuromorphic) computing has recently demonstrated advancements in pattern and image recognition as well as classification of unstructured (big) data. However, the volatility and energy required for neuromorphic devices presented to date significantly complicate the path to achieve the interconnectivity and efficiency of the brain. In previous work, recently published in Nature Materials, the PI has demonstrated a low-cost solution to these drawbacks: an organic artificial synapse as a building-block for organic neuromorphics. The conductance of this single synapse can be accurately tuned by controlled ion injection in the conductive polymer, which could trigger unprecedented low-energy analogue computing. Hence, the major challenge in the largely unexplored field of organic neuromorphics, is to create an interconnected network of these synapses to obtain a true neuromorphic array which will not only be exceptionally pioneering in materials research for neuromorphics and machine-learning, but can also be adopted in a multitude of vital medical research devices. BIOMORPHIC will develop a unique brain-inspired organic lab-on-a-chip in which microfluidics integrated with sensors, collecting characteristics of biological cells, will serve as input to the neuromorphic array. BIOMORPHIC will combine modular microfluidics and machine-learning to develop a novel platform for low-cost lab-on-a-chip devices capable of on-chip cell classification.In particular, BIOMORPHIC will focus on the detection of circulating tumour cells (CTC). Current methods for the detection of cancer are generally invasive, whereas analysing CTCs in blood offers a highly desired alternative. However, accurately detecting and isolating these cells remains a challenge due to their low preval
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fourth Framework proposal on 'Evaluation of local socio-economic strategies in disadvantaged urban areas'.

assistant: **Innovation**

The project will evaluate the impact of local economic development strategies as implemented in six urban regeneration areas in six countries (D, FR, I, NL, SE, UK) and it will analyse the conditions influencing the effectiveness of such strategies. Local economic development strategies aim at the integration of disadvantaged communities by means of generating employment and increased incomes, and the revival of the whole local economy in deprived urban areas. The project has built users into its design and planning and proposes tandem"-solutions - that is the co-operation of a research partner and an associated local partner in each of the participating countries - to undertake the research. The key hypotheses of the research are that local economic development strategies at the neighbourhood level create an "added value" that could not be realized with centrally devised policies at city and/or higher policy levels. It is further assumed that certain institutional and organisational characteristics, like an integrated and comprehensive approach and its kind of embeddedness into policy systems at higher levels, are of crucial importance to their effectiveness to create economic opportunities for the social integration of disadvantaged communities. The research aims at: - comparing the impact of local development strategies as employed in different European countries - comparing the effectiveness of local development strategies in different local and national circumstances - understanding better how different institutional and organisational structures and interrelationships condition the effectiveness of local economic development strategies - identifying areas for improvement and defining appropriate policy solutions - developing appropriate indicators for monitoring l
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'The Fablab for geodata-driven innovation - by leveraging Space data in particular, in Universities 2.0'.

assistant: **Objectives**

FabSpace 2.0 aims at making universities open innovation centres for their region and improving their contribution to the performance of societies. It will concentrate on one innovation area with high expected socio-economic and environmental impact: geodata-driven innovation, by leveraging space data in particular.When Universities must endorse a new role as co-creators of innovations in the context of Science 2.0 principles, the future realisation of open data as a new innovation scene needs to set up a creative environment in which developers from the civil society or industry or the academic research, public administrations and civil organisations can meet, work together, co-create new tools and business models.The proposal consists in a new kind of fab labs: FabSpaces. A fab lab is a one-stop shop access to any materials, machines and tools to digitally manufacture new products, a FabSpace will be a one-stop shop-access to a range of data (incl. space data), free software & data processing tools, to develop new applications.FabSpace 2.0 will provide a new free-access service and place dedicated to collaborative data-driven innovation in 6 European universities (13 at the end of the project). Through online support, entrepreneurship & innovation leadership trainings for students and researchers, the human capital among FabSpace users will be enhanced. The link between universities, industry, the public sector and civil society will be strengthened with local and European actions/events consisting in developing new applications to tackle challenges launched by ONGs & companies. 1500 students and researchers are expected to use FabSpaces, half of them will participate in workshops and 21 teams will be invited to events were they will meet experts and start-ups. FabSpa
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'A novel two-step model for neurodegeneration in Parkinson’s disease' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

Parkinson’s disease (PD) is the second most common neurodegenerative disorder primarily caused by the progressive loss of dopaminergic (DA) neurons in the substantia nigra (SN). Despite the advances in gene discovery associated with PD, the knowledge of the PD pathogenesis is largely limited to the involvement of these genes in the generic cell death pathways, and why degeneration is specific to DA neurons and why the degeneration is progressive remain enigmatic. Broad goal of our work is therefore to elucidate the mechanisms underlying specific and progressive DA neuron degeneration in PD. Our new Drosophila model of PD ⎯Fer2 gene loss-of-function mutation⎯ is unusually well suited to address these questions. Fer2 mutants exhibit specific and progressive death of brain DA neurons as well as severe locomotor defects and short life span. Strikingly, the death of DA neuron is initiated in a small cluster of Fer2-expressing DA neurons and subsequently propagates to Fer2-negative DA neurons. We therefore propose a novel two-step model of the neurodegeneration in PD: primary cell death occurs in a specific subset of dopamindegic neurons that are genetically defined, and subsequently the failure of the neuronal connectivity triggers and propagates secondary cell death to remaining DA neurons. In this research, we will test this hypothesis and investigate the underlying molecular mechanisms. This will be the first study to examine circuit-dependency in DA neuron degeneration. Our approach will use a combination of non-biased genomic techniques and candidate-based screening, in addition to the powerful Drosophila genetic toolbox. Furthermore, to test this hypothesis beyond the Drosophila model, we will establish new mouse models of PD that exhibit progressive DA neuron degenera
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Study of the role of m6A RNA methylation in the nervous system of Drosophila melanogaster: an in-vivo model to dissect the impact of epitranscriptome reprogramming in physiology and cancer' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

The identification of reversible m6A RNA modification strongly points towards the existence of a novel level of complexity of gene expression regulation. Recent studies have suggested that m6A might be involved in several biological processes and that dysregulation of this modification may contributes to neuro-developmental abnormalities and cancer. The aim of the described research is to clarify the role of m6A RNA modification in the nervous system in physiological conditions -during brain development - and to discover its contribution to pathological conditions - Glioblastoma. To achieve this goal I propose to use Drosophila melanogaster to study : Aim 1 the impact of perturbing  different members of the m6A machinery on brain morphology, progenitors differentiation and neuronal axon growth and guidance; Aim2 the impact of modulating the levels of m6A RNA modification in a Glioblastoma model and study the effect of this perturbation on tumor growth and progression. The results obtained will be of fundamental importance for the development of the field of epitranscriptomics by shedding light on the biological outcome of  m6A modification in-vivo. In particular, Drosophila might become an efficient model to screen for novel members of the m6A machinery and to clarify how m6A is read and translated into a biological response. Finally, the data obtained by the analysis of the Glioblastoma model, will strongly contribute to the understanding of the link between RNA methylation and tumor development and aggressiveness.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Symposium on acoustics in fisheries and aquatic ecology' to be submitted under Fifth Framework.

assistant: **Abstract**

Recently the scope of acoustics has increased dramatically and underwater acoustics provide information to fisheries biologists and ecologists, in most aquatic ecosystems: from the deepest oceans to extremely shallow waters, from unicellular organisms to biggest marine mammals for pelagic, demersal and benthic populations, bottom type and benthic plants. Acoustics allows observing and assessing under water ecosystems on a continuous basis.The Symposium on acoustics applied to aqua-tic systems will explore recent advances and the expansion of acoustical methods into a broad range of environments with new analytical techniques, technologies, concepts and methods, and innovative acoustical implementations. An important effort will be done for dissemination of the results and discussions. Selected papers (through peer reviewing) will be published in an international journal and a synthesis will be made available to the public through a specific web page.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Enterprise Lazio and Sardegna for Europe SMEs Innovation Management 2019' in the context of a Horizon 2020 call.

assistant: **Objectives**

EEN consortia partners will improve their action providing on site support to SMEs, and becoming a part of the companies for assessing their capacity in the innovation management issues. The ELSE – SIM 2019 (Enterprise Lazio and Sardegna for Europe- SMEs Innovation Management) consortium as a whole is able to provide the expectedservices:Key Account Management• Assess SME gaps and needs,• Facilitate the identification and the initial coach-SME interaction to prepare coaching plan,• Support companies in the project management and administrationEnhancing SME innovation management capacity ,• Asses innovation management capacity based on performance,• Action plan implementation


**Keywords:** Innovation managmener, Assess, Access 2 Finance, Coach
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Cultural Heritage and Identities of Europe's Future'.

assistant: **Concept**

Today, the twinned ideas of respect towards minorities’ rights and cultural diversity that have been projected as values derived from the European historical experience are facing well-documented challenges. These include: the current radicalisation of young people in Europe; processes questioning the meaningfulness of the European project; and the revival of tribal identities and separatism. These processes give cause to fundamentally rethink the idea of Europeanness as a culture of dialogue and mutual respect. CHIEF aims to build an effective dialogue between different stakeholders in order to facilitate a future of Europe based on more inclusive notions of cultural heritage and identity. The project is innovative in its approach to cultural literacy of young Europeans by privileging the importance of production and transition of cultural knowledge in both formal educational settings initiated from above, and a variety of informal human interactions. These informal interactions are often overlooked despite their strong influence on how knowledge about European culture is acquired by young people. The project proposes to explore them by building an inter-disciplinary, multi-sectoral and transnational partnership in nine countries in and outside the EU. Through its research activities and social interventions, CHIEF will have a substantial impact on policies and practices facilitating intercultural dialogue in Europe. It will contribute to understanding and enhancing cultural literacy for young people, resulting in greater appreciation of diversity. The project will lead to more effective use of European cultural heritage as a site of production, translation and exchange of heterogeneous cultural knowledge. Moreover, it will help to recognize existing innovative practic
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Seventh Framework proposal on 'Molecular mechanisms of myelination in peripheral nerves'.

assistant: **Concept**

Peripheral nerve myelination by Schwann cells is essential for normal nervous system function. Numerous acquired and inherited diseases result from defects in peripheral nerve myelination or myelin maintenance. In addition myelination is crucial for repair and regeneration of the nervous system. Thus an important challenge is to understand the cellular and molecular events that underlie myelination and myelin maintenance. The host laboratory, under the direction of Dr Nicolas Tricaud, has developed a novel in vivo approach to investigate the basic molecular mechanisms that control myelination, myelin maintenance and demyelination. This technique involves microinjection of viral vectors that express cDNAs and small inhibitory RNAs in myelinating Schwann cells of mice. The aim of the present proposal is to use this approach to analyse the basic cellular mechanisms, with particular focus on cell-cell interactions, involved in the aetiology of demyelinating peripheral neuropathies. In addition increasing evidence suggests that numerous hereditary and acquired peripheral nerves diseases present with significant mitochondrial dysfunctions. The relationship between the function of mitochondria in mSCs and in peripheral axons remains unknown. Therefore the second aim of this project is to investigate both the role of mitochondria in mSCs and to evaluate the impact of glial mitochondrial activities on the physiology and function of the myelinated axon. The present proposal will provide key information about peripheral myelination and maintenance with particular relevance to the aetiology of peripheral neuropathies, information crucial for the development of therapeutic strategies for these highly debilitating diseases.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'Implementation of a Transeuropean Knowledge Voucher System'.

assistant: **Innovation**

KVoucher aims at implementing a transregional Knowledge Voucher System that will facilitate contact making and initiating first projects between SMEs from one region and so called Knowledge Institutes (KIs) from other regions in different countries. A Knowledge Voucher is a coupon that entitles SMEs to receive a certain amount of consultancy or research from knowledge-intensive organisations, so-called Knowledge Institutions (KIs). A company in one region will through a KVoucher get the possibility to “buy competence” and carry out a joint activity with a provider – a KI,– in the other region. The project will reach its overall goal through the achievement of the following specific objectives: • Prepare a standardized methodology and toolkit for the description, analysis and benchmarking of existing voucher systems and apply it to the partner regions • Develop common specifications for a shared transregional voucher system as well as a mechanism to adapt it to any specific EU environments. KVoucher will become integrated with existing systems in partner regions, and will be the foundation for a new system in partner regions that do not have one. • Provide SMEs, Knowledge Institutions and stakeholders with proper tools in order to access, use and maintain a voucher system • Analyse the conditions under which a joint Kvoucher pilot could be carried and prepare an action plan for its implementation • Implement a real-life joint pilot in order to validate the transregional voucher system with some SMEs in each partner region getting a voucher to receive support from KIs located in the remaining partner regions • Design and apply a set of indicators in order to evaluate the performance of the transregional voucher system • Execute the proper dissemination actions in order to
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Cost competitive eco-friendly and acoustic wooden doors for indoor applications' (ECO-SILENTWOOD) under Horizon 2020.

assistant: **Objectives**

Windows and doors are key components to ensure the noise insulation of a room. Some sectors, looks for noise reduction solutions in indoor doors, in order to ensure the comfort. That is the case of (a) Medical applications: 35dBA of S.R.I. would cover most of customer and regulatory demands; (b) Hotel door applications (customers demands 34dBA); Dwelling entrances (customers demand over 35-38dB). We are going to define the exploitation strategies to ensure a  5% market share  of the European doors market for dwelling building, education and sanitation centres by year 5, with a total cumulated turnover of € 23.8 million.To meet this goal we wil launch a  a product that ensures 37 dBA for doors, with a maximum thickness of 45 mm and maximum wight of 70kg.. Current prototypes of our technology reach even 42 dBA of SRI. Our wood door is fire resistance at EI30 (meaning the door can keep its integrity at least 30 minutes in case of fire) with a maximum door thickness of 45 mm and a maximum weight of 70 kg. Besides, and looking for complying with national eco-bales, our doors are based on eco-friendly materials: (a) wood wool instead of rock wool, (b) 100% recycled acoustic underlay manufactured from a combination of cork granules and rubber crumb or by a wood fibre and cork material instead of promasound and (c) recycled plastic/wood composite (instead of plastic/wood composite). This will give us access to a new market nice: the green building sector.To be unique in the market, our door must ensure a cost under 650 €, therefore we will establish a LEAN manufacturing strategy that will allow for a15% cost reduction with respect to the SILENTWOOD proposed solution (actual prices is around 800 to 900 € per door).