RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'New optimisation approaches for atfm' (NOAA).

assistant: **Innovation**

The NOAA study will investigate and undertake research into flow management problems in order to develop optimised and integrated ATFM techniques . This is performed in order to recommend appropriate methods for the optimisation of ATFM procedures which will provide the basis for the further developments needed for a unified ATFM system of next generation.The research will optimise the algorithms used for flow planning and investigate the impact on the controller tasks and the requirement for information to support the flow planning activities. The linkage of these activities to provide an efficient overall flow management system will also be addressed. This will result in an optimisation of ATFM procedures, sequencing and metering, departure management and tactical flow management. %
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Arabidopsis zygotic and somatic embryogenenis' demonstrating excellence, impact and implementation quality for a Fourth Framework call.

assistant: **Abstract**

Plant somatic embryogenesis is a process of major importance to the rapid multiplication of elite cultivars in crop species. The genetic dissection of zygotic embryogenesis has led to the identification of genes involved in apical-basal and radial pattern formation. In this project we want to compare the formation of apical-basal and radial pattern elements in zygotic and somatic embryogenesis in the model species Arabidopsis thaliana. The possibility to study zygotic embryo mutants under in-vitro conditions also allows to determine the effects of particular plant-produced signal molecules on pattern formation. The availability of targeted gene disruption methods in Arabidopsis will be employed to obtain mutants in several genes thought to be involved in the generation of specific signal molecules as well as in genes involved in establishing the correct division planes of the early embryo. The specific probes obtained and the signal molecules identified will be tested in the unrelated species of grapevine, a species for which somatic embryogenesis of all cultivars is a key issue to develop mass propagation and gene transfer techniques. The project aims to produce specific markers useful for assessing the regenerative state of the somatic tissue, and at the same time aims to test specific and new signal molecules such as arabinogalactan proteins (AGPs), and small recently identified plant-produced peptides. Both compounds appear to promote the frequency of embryogenic cell formation In addition, the project aims to study several genes, identified by mutation or identified by sequence homology to known genes in other species. These genes encode proteins thought to be involved in signalling systems that originate in the integuments, the embryo sac and the endosperrn, and a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fifth Framework proposal for the project 'E-Factors: A Thematic Network in E-Business Models'.

assistant: **Objectives**

The E-factors project aims to set up a thematic network dedicated to bringing together universities, research centers and practitioners with a common objective: To determine factors of broad and sustainable adoption of new business models based on e-Business practices and research expertise across Europe. The E-Factors network will actively seek to transfer skills and experiences with a view to generating strategic implications in the implementation of e-business models and disseminating this knowledge across Europe.OBJECTIVESTo collect, organise and disseminate experiences gained in individual projects on market opportunities and constraints. To develop a list of common issues and ideas as to how individual project results (both in terms of findings and in terms of methods of research work adopted) can be combined and further developed to produce complementary results. To construct a report that the EU can use to formulate future strategic implications. Knowledge will be drawn from the expertise of leading universities and current IST projects conducting research in e-business models as well as their adoption and their socio-economic implications. To develop means, to support the dissemination of the combined knowledge of the thematic network participants to a broad range of stakeholders within Europe. To promote and guide further research and development in the area of e-business model adoption through the collaboration of academe and industry.DESCRIPTION OF WORKE-Factors is scheduled to cover a period of 18 months. The work plan of E-Factors has been structured around 6 work-packages. WP1 is concerned with E-factors project management structure that will glue together and co-ordinate all project activities. WP2 will be concerned with setting up a Web-based infrastruc
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Unsteady aeroelastic control for multi-MW wind turbine rotors' (UNAELCO).

assistant: **Concept**

The overall objective of the project is to enhance the knowledge and develop advanced methods and tools for the research and development of unsteady aeroelastic control concepts for multi-MW wind turbine rotors. The focus is on the development of deeper understanding of the unsteady aerodynamics phenomena in combination with the operation of the distributed load control devices in wind turbines and on the evaluation of the benefits of using advanced models and controllers in the predictions of aeroelastic simulations. From the present stage of proven concepts, and first order numerical and experimental predictions, the project will contribute to the development of the research field to a new stage where it constitutes a complete, reliable and robust approach to system design, which is ready for prototype testing, with the target towards lowering the cost of energy produced by modern large-scale wind turbines. This will further strengthen the knowledge transfer and integration in the research field and enhance the collaboration between relevant research institutes.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'How to Replicate Chromatin - Maturation, Timing Control and Stress-Induced Aberrations' to be submitted under Seventh Framework.

assistant: **Abstract**

Inheritance of DNA sequence and its proper organization into chromatin is fundamental for eukaryotic life. The challenge of propagating genetic and epigenetic information is met in S phase and entails genome-wide disruption and restoration of chromatin coupled to faithful copying of DNA. How specific chromatin structures are restored on new DNA and transmitted through mitotic cell division remains a fundamental question in biology central to understand cell fate and identity.Chromatin restoration on new DNA involves a complex set of events including nucleosome assembly and remodelling, restoration of marks on DNA and histones, deposition of histone variants and establishment of higher order chromosomal structures including sister-chromatid cohesion. To dissect these fundamental processes and their coordination in time and space with DNA replication, we have developed a novel technology termed nascent chromatin capture (NCC) that provides unique possibility for biochemical and proteomic analysis of chromatin replication in human cells. I propose to apply this innovative cutting-edge technique for a comprehensive characterization of chromatin restoration during DNA replication and to reveal how replication timing and genotoxic stress impact on final chromatin state. This highly topical project brings together the fields of chromatin biology, DNA replication, epigenetics and genome stability and we expect to make groundbreaking discoveries that will improve our understanding of human development, somatic cell reprogramming and complex diseases like cancer.The proposed research will 1) identify and characterize novel mechanisms in chromatin restoration and 2) address molecularly how replication timing and genotoxic insults influence chromatin maturation and final chromatin
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Paving the ground for the second generation of a highly effective, application oriented MicroNano Manufacturing community in Europe' to be submitted under Seventh Framework.

assistant: **Abstract**

MINAM 2.0 will contribute to enabling a new dimension of quality with respect to the cooperation of the single groups in the micro- and nanotechnology (MN) manufacturing. MINAM aims at bringing together existing and well established (local) Micro Nano related organizations:  the microclusters in the European regions, networks of Excellence, Associations, Research infrastructures, European projects and decision makers in the MN community. Through regional clusters with their strong industrial backbone MINAM 2.0 considerably contributes to the participation of the industry in European decision processes in this thematic area.The cooperation between MINAM and European application and technology platforms promoted at European level will improve the exchange between application requirements and technical capabilities, aiming at the identification of common objectives and requirements.MINAM will provide a significant contribution to identification of Cross sectional Joint Research agenda (together with other ETP´s) and allows for a derivation of concerted partial roadmaps for the different thematic areas in MNT (Assembly, Micro/Nanotechnologies, System integration).To obtain sustainability MINAM 2.0 will be established as a “one stop shop” hub for exchanging information, adding value to all players in this area of interest. The hub will also push the improvement of cooperation between the regional key players in the European regions.A close connection to Manufuture, Nanofutures and other ETPs in the NMP area  will ensure that double activities are cut down to a minimum and strenghten the production technology as a whole through its specific view on aspect of highly micro relevance, such as precission assembly, characterization, micro sensorics, etc.For the intended target app
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project '3P-Tec - Three-parent breeding technology for plants of the future' (3P-Tec), addressing dissemination and exploitation.

assistant: **Impact**

Background: There is an urgent need for an agricultural revolution to generate climate-resilient cultivars, which combine proven traits with novel qualities adapting crop plants to climate extremes, including heat and drought. Novel breeding technologies can make the difference to enable farmers to achieve high yields with climate-robust crops to secure food supplies for the world's population. Breakthrough technology: In the framework of the ERC Consolidator Grant ""bi-BLOCK"" we discovered that plant egg cells can fuse with two sperm producing offspring with three parents instead of two - one mother and two fathers - bypassing a hybridization barrier that is a major limitation for conventional plant breeding approaches. The three-parent breeding technology (3P-Tec) literally opens the way for exploiting beneficial traits of previously incompatible climate-adapted wild species. In the framework of the ERC Proof of Concept grant ""TriVolve"", we teamed up with one of the world's leading plant breeding companies (KWS Saat SE & Co. KGaA), and successfully transferred the strategy to sugar beet as an experimental crop prototype. Objectives: The development of the 3P-Tec technology for further crop plants including potato, the establishment of technologies that enhance the efficiency of obtaining three parent plants, and the commercial exploitation of 3P-Tec are aims of this project. The project capitalizes on the breeding know-how, worldwide networks, and commercialization expertise of the breeders Aardevo and KWS.Impact: 3P-Tec will revolutionize the ability of breeders to develop improved crops in providing a tool to mine beneficial gene variants of currently incompatible species and to substantially shorten time to market of climate-adapted seed varieties. It provides a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'COST EFFECTIVE REACTIVATION AND MODERNISATION OF SHPS IN LUXEMBOURG' in the context of a Fourth Framework call.

assistant: **Objectives**

Agence de l'Energie S.A. has coordinated a similar project between 1993 and 1995 for the Ministry of Energy concerning 11 grid connected SHPS in Luxembourg.The aim of the present THERMIE project is to rehabilitate and modernize 16 small hydro-power sites (private properties) in Luxembourg (average electric power - 50 kW).Technical goals:- Implemention of german, french and belgian technology,- Improving the efficiency of the actual turbines,- Increasing the energy production,- Connecting SHPS to the electric grid,- Integrating fishpasses into the weir,- Collaboration of a high school in Luxembourg (Institut Superieur de Technologie).- Increase of the annual energy production from about 1.000.000 kWh to 4.100.000 kWh- Reduction of CO2 emissions: 2942 tons/year- Installed total electrical power: 749.5 kWThere are 3 sites on a reserve list.1. INNOVATIVE TECHNOLOGY- Use of modern control systems- Power electronics- Low energy consuming turbine regulation sytems- Implementation of single regulated Kaplan turbines; cost effective solution - Installation of automatic trash racks- Technically and economically optimised combination of the services provided by the different manufacturers.2. CONTEXT IN WHICH THE TECHNOLOGY IS OPERATINGThe goal of this project is to modernize and rehabiliate SHPS in Luxembourg- 60% of the sites are reactivations- manual regulation will be replaced by automatic regulation- the expected life time of the turbines will be increased- automatic trash rack cleaning systems will be installed.The innovative part consists mainly in the global approach (national level) and in the technically and economically optimised combination of the components.3. ECONOMIC ASPECTS OF THE TECHNOLOGYAs the average electric power (50 kW) is quite low, the specific cost for th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'The Time is Now: Understanding Social Network Dynamics Using Relational Event Histories' (TIMEISNOW), addressing dissemination and exploitation.

assistant: **Impact**

Relational event history data are becoming increasingly available due to new technical developments. These data contain detailed information about who interacted with whom in a network and when. For example, employees wear sociometric badges storing time-stamped interactions between colleagues, classrooms are monitored to observe interactions between teachers and students, and police databases store violent interactions between criminal gangs in city districts.This new type of data has the potential to greatly contribute to our understanding of dynamic social networks by providing new insights about speed, rhythm, duration, and lag in social interactions. However a crucial problem is that statistical tools for analyzing such data are currently underdeveloped. We are therefore unable to exploit this treasure of information, resulting in a limited understanding about the evolution of social relations in continuous time.I will undertake the following actions to resolve this fundamental shortcoming. First, I will develop an innovative Bayesian statistical framework for the analysis of relational event histories by building upon the novel relational event model, which has great potential but is in a preliminary stage of development. Second, I will implement the new framework in free and user-friendly software to ensure general utilization among social scientists. Third, in collaboration with network experts in organizational sociology, sociology of education, and criminology, I will develop tailor-made extensions for dynamic social processes in important applications.In sum, this project will yield a groundbreaking new methodology for testing and building theories on time-sensitive processes in social networks. It will allow us to research, among others, how fast integration
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Biomolecular image processing tool' (1998-2002), addressing dissemination and exploitation.

assistant: **Impact**

Bio Image is focused on analytical detection, image processing and visual inspection of bio molecules, potentially affected by pathological diseases/markers, through a scanning probe microscopy sum for diagnostic applications. Research goal is the saw/hw/mechanical development, testing, validation of a prototype to analyse bio molecules DNA, bacteria and allow: binding of dank probes and monoclonal antibodies mob to silicon tips: analytical detection of biomoleclules interaction force with complementary molecules (polynucleotides, antibodies) and measurement of interaction by specific image processing/visual tools; saw interpretative support of pathological diseases. Project expected outcomes are: methodological (adapt stem microscopes to diagnostics application and develop a user -friendly methodology for diagnostics) and industrial (develop a hw/saw system able to be applied repeatedly in the target market and develop a tool to reduce diagnostic costs).
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'TEXAD – Tailoring EXosomes for Autoimmune Diseases', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Exogenus Therapeutics is a drug development company using an exosome-based platform technology to develop an innovative pipeline of therapeutic products. Exogenus’ scientific team has pioneer research work in the area of Umbilical Cord Blood (UCB)-derived Extracellular Vesicles (EVs) clinical application. Among EVs, exosomes are nanosized vesicles (30-150nm) released from all types of cells responsible for cell-to-cell communication. Exogenus’ technology makes use of UCB cells preconditioned in ischemia, which secrete EVs enriched in pro-regenerative, anti-inflammatory and immunomodulatory biomolecules. Based on immunomodulatory properties of the lead biological active agent under development (Exo-101), and its capacity to increase immunotolerance, the company is investigating the potential of these vesicles for the treatment of autoimmune diseases. There are more than 80 different autoimmune diseases (AD) and a prevalence of more than 50 million people in the US alone. There is a high unmet need for most of these diseases, especially regarding safer treatments with less secondary effects. Based on their proprietary vesicles derived from UCB, Exogenus aims to develop a new generation of biologics for AD, with high efficacy and less secondary effects.