RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Seventh Framework proposal on 'River networks as ecological corridors for biodiversity, populations and waterborne disease (RINEC)'.

assistant: **Innovation**

The proposal hinges on the noteworthy scientific perspectives provided by ecohydrological studies  of river basins,seen as a natural laboratory for complex system perspectives integrating hydrologic, ecological and geomorphological dynamics. Moving from morphological and functional analyses of dendritic geometries  observed in Nature over a wide range of scales,my claim is that essential processes sustaining human life and societies taking place along  dendritic structures can be predicted.  Population migrations and human settlements historically proceeded along river networks to follow water supply routes. Riparian systems,critically important ecosystems positioned along streams and rivers, play crucial roles in their watersheds,including nutrient filtering, biogeochemical processing,shade and resource provisioning, and stream bank stabilization. Devastating water-borne disease,such as cholera, and invading foreign species spread through water bodies linked by river networks. Although the dynamics of such systems has been extensively studied, existing approaches were mostly within the framework of mean-field or two-dimensional landscapes that ignore directionality of dispersal implied by the network acting as environmental matrix. How does connectivity within a a river network affect the emergent spreading of water-borne infections?  Does the river basin act as a template for biodiversity? Are there hydrologic controls on the spreading of water-borne disease? To answer such questions, the present proposal addresses the  study of  biodiversity in the river basin (freshwater fish and riparian vegetation); cholera dynamics  and zebra mussel invasions along river networks. Observational data and theoretical models, in a comparative mode,will be analyzed within  a unified
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Genetic Message Oriented Secure Middleware' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

The core scientific focus of GEMOM is the significant and measurable increase in end-to-end intelligence and resilience of complex, distributed information systems. <br/>GEMOM's definition of intelligence and resilience include:<br/>- Insensitivity or significant reduction in sensitivity to individual and sometimes multiple faults in the system. Fault is defined as any deterioration of the functional profile of informational system, the volumetric profile, and  the security profile<br/>- Support for a reconfiguration as an efficient system<br/>The primary objective of GEMOM is to research, develop and deploy a prototype of a messaging platform that is evolutionary, self-organising, self healing, scalable and secure. GEMOM will be resilient and be able to utilise redundant modules (hot-swap or switchover) instantly without information loss. These resilience features will allow specialist, independent system actors, viz. watch-dogs, security and situation monitors, routers, and other optimisers, to remove or replace compromised nodes from the broader network instantly without compromising higher level functionality.<br/>GEMOM considers the Publish-Subscribe variant of Message Oriented Middleware to be the predominant one and will focus on issues surrounding that kind of messaging. For completeness GEMOM would provide a synchronous Request and Reply overlay as well. <br/>The advances that GEMOM proposes to make to the area of messaging revolve around the notion of a fault". In addition to the intuitive understanding of what a fault might be, whereby any actor stops being operable, connection is lost etc, GEMOM extends the notion of fault to include compromised security or inadequate bandwidth availability in the first iteration and compromised abstract notion of "resource"
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Curved Optoelectronic System to Monitor Ocular Signals' (COSMOS).

assistant: **Innovation**

COSMOS is a highly multi-disciplinary project that will deliver the first technology for the continuous recording of cell resting membrane potentials. Biological electric fields arise by ion transport across cell membranes and tissues, and represent a crucial cue in guiding cellular differentiation (e.g., stem cells), mutation (e.g., cancer cells), and migration (e.g., wound healing). However, the underlying mechanisms behind these phenomena are yet to be fully discovered. This is because this data is currently hard to access with existing technologies: microelectrode arrays rely on electroporation (i.e. probing the cell membrane with consequent disruption, which makes it challenging to perform prolonged measurements), the patch-clamp method has a low throughput, and novel optical technologies mainly addressed the measurement of action potentials. However, most cells in the human body do not fire action potentials, and they communicate in a narrower electrical range. COSMOS will implement a platform to perform contact-free recordings of membrane potentials by optically mirroring the cell membrane charge. This technology will be first applied in testing corneal regenerative technologies (topical drugs, limbal stem cells, post-corneal transplant monitoring), as corneal wounds are an excellent model to study electric field-regulated cell behavior. COSMOS will provide the technological tool to enable addressing a fundamental scientific question, as well as pave the way towards new diagnostic methods, therapeutic strategies, and in vitro drug testing platforms.


**Keywords:** Bioelectricity, Electrophysiological recording, Membrane potential, Nanofabrication, Corneal wound healing, Corneal tissue engineering, Drug testing, Regenerative medicine
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Novel post-genomic cell-based screens for drug targeting in membrane protein disorders' demonstrating excellence, impact and implementation quality for a Sixth Framework call.

assistant: **Abstract**

Elucidation of protein function is the next post-genomic challenge towards the understanding of biological processes in health and disease. Transcriptomics and proteomics approaches usually deliver long lists of candidate" gene that are putatively associated with the respective disease. However, no functional information nor direct relationship with the pathology, is established. Strategies and tools are thus critically needed to distinguish genes and proteins with mere pathologic association from those primarily responsible for the basic cellular defect(s) in such pathologies. Membrane proteins, including receptors, channels, antibodies, transporters, etc. play major roles in cells and organisms as they are involved in important cellular mechanisms, such as communication, immunity, signalling and response to environmental stimuli."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Radial basis functions' to be submitted under Fourth Framework.

assistant: **Abstract**

Radial basis functions can provide excellent global approximations to surfaces and multivariate functions. Relevant problems arise throughout science, engineering and mathematical finance, so that there are numerous applications. Great theoretical progress has been made during the past decade, but efficient algorithms for the constuction and use of radial basis functions are not yet available. However, several methods show great promise. In particular, (i) the modification of 'n-body problem' codes for the evaluation of radial basis functions, and (ii) the investigation of iterative methods, specifically the preconditioned conjugate gradient algorithm, for the solution of the linear systems required. Therefore there is great scope for improving and implementing the work of, for example, Beatson, Powell, Dyn and Baxter. This major task is the main aim of the project. Further, no work has yet been done on the use of parallel computers for these computations, and the project aims to initiate this study. All code resulting will be made available via the World Wide Web
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Switched/Synchronous Reluctance Magnet-free Motors for Electric Vehicles' goes beyond current state-of-the-art under Seventh Framework.

assistant: **Innovation**

For a large scale introduction of Electric Vehicles (EV) in Europe, adequate volume supply of current PM based motors could be at risk, as the rare earth metals they contain can only be found under single source monopolies. In this context, the development of high efficiency motors using a limited amount of permanent magnets or completely new magnet-free motor designs is crucial. A promising option for this new generation of electric motors could be reluctance technology, which has been left out of the first line up to now due to its lower power density when compared to PM motors. On the other hand, the use of axial-flux configurations has proved recently in PM motors that power density can be increased in a relatively cost-effective way. The combination of both approaches, reluctance motors in axial-flux configuration, could lead to power densities comparable to those of PM motors in current EV-s while minimizing (PM assisted synchronous reluctance motors, PMSynRM) or avoiding (switched reluctance motors, SRM) the usage of scarce magnet materials. The aim of this project is to develop both axial-flux SRMs and PMSynRMs in parallel (meeting EV power density requirements), exploiting their commonalities and synergies in the design and prototyping phases, to further opt for the most suitable solution to be integrated in commercial EV-s. Being the combination of reluctance technology and axial-flux configuration a completely novel approach for EV applications (SRMs) and for any kind of application in general (PMSynRMs), one of the main challenges of the project will be to get a cost-effective and high efficiency motor design, considering a potential large scale manufacturing and industrialization of this new generation of motors.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Understanding small RNA-mediated transposon control at the level of chromatin in the animal germline' in the context of a Horizon 2020 call.

assistant: **Objectives**

Transposable elements—universal components of genomes—pose a major threat to genome integrity due to their mutagenic character. In all eukaryotic lineages small RNA pathways act as defense systems to protect the host genome against the activity of transposons. The central pathway in animals is the gonad-specific PIWI interacting RNA (piRNA) pathway, one of the most elaborate but also least understood small RNA silencing systems.Here I propose to study the interplay between the piRNA pathway and chromatin biology in Drosophila with two aims: First, we will identify the factors and investigate the processes that underlie piRNA-guided silencing in the nucleus. Our objective is to understand how recruitment of an Argonaute protein to a nascent RNA mechanistically leads to the assembly of effector proteins that govern heterochromatin formation and transcriptional silencing. Second, we will study the biology of piRNA clusters, heterochromatic loci that encompass a library of transposon fragments and that act as the pathway’s memory system. Our goal is to uncover how a group of proteins—several of which are germline-specific variants of basic cellular factors—enable transcription within heterochromatin and control the downstream fate of the emerging non-coding RNAs. Our work centers on the piRNA pathway in Drosophila ovaries, undeniably the model system at the forefront of the field. By combining the strength of fly genetics with the power of genome-wide approaches we will uncover how heterochromatin on the one hand governs silencing and how the piRNA pathway on the other hand exploits it to facilitate the transcription of piRNA precursors. This will reveal fundamental insights into the co-evolution of transposons and host genomes. At the same time, by studying the piRNA pathw
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Pervasive muscle response monitoring for everyone, a physiotherapy revolution' goes beyond current state-of-the-art under Horizon 2020.

assistant: **Innovation**

Almost all of us have suffered a Musculoskeletal disorder (MSD) of some type or another. Whilst for several of us a back, orneck ache can go with minor intervention, for many the problem can be chronic. Home life becomes a daily struggle, workcan not be completed and lively hoods are ruined.At mDurance we have been developing a product that can rapidly analyse the complex data from non-invasive EMG(Electromyographic) sensors and present this to physiotherapists in an understandable format. EMG analysis allowsvisualisation of the electrical activity of the skeletal muscles in order to precisely pin-point which muscles are performing asthey should and which are not. Current solutions that attempt to do this needed custom adaptation to each patient andsituation, useful results take upto 45 minutes to generate and the costs are prohibitive for the overwhelming majority ofphysiotherapists.Based on the result of several years of research work and various scientific papers, mDurance has unique data processingthat generates results within 5minutes. Running in the cloud and using low-cost EMG sensors we are aiming to drive uptakeof this form of patient analysis to standard physiotherapist clinics. The result will be much faster MSD diagnosis and properlytargeted and monitored rehabilitation exercises and processes. Additionally, we also target Hospitals and other organisationsassessing the capacity of workers, as well as the sports market where we can increment athlete performance, better protectagainst injury and decrease rehabilitation times.The market is vast. There are over 1 million physiotherapy specialists worldwide and around 200,000 Health & WellbeingCentres plus professional and high performance sport clubs together worldwide. With a dedicated go-to-market plan, we aim
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Facing Inequalities and democratic challenges through Co-production in Cities' to be submitted under Horizon Europe.

assistant: **Abstract**

If the link between inequalities and declining levels of trust in the political institutions of democracy in Europe has already been shown, the various ways in which both citizens and institutions are trying to face these inequalities and (re)build a sustainable common future remain somewhat under-documented. Indeed, this lacuna becomes even more pronounced when one considers those attempts that go beyond conventional forms of state-led participation. Responding to this gap, the aim of Fairville is to both document and propose pilot models of urban intervention that engage local academics, -authorities, -community-based organisations, -residents and -users in the collective improvement of deprived urban neighbourhoods via a deepening of resident and user participation in new and existing democratic processes. The idea that urban policies should not be made ""for"" populations but rather “with"" them is a potentially profound engine of social transformation and empowerment. However, the realisation of such co-production processes is often marked by epistemic inequalities and unequal power relations. Cognisant of this issue, the Fairville pilot cases all place an emphasis on exploring the ways in which academic researchers, local communities and local authority representatives can work together to reduce the power and information asymmetries that exist between them. Clustered around three major themes - environmental inequalities, inequalities related to housing and urban planning and inequalities related to climate risks – and ranging from co-diagnosis to co-planning and intervention, the pilots will be carried out as action research and include the implementation of observation, capitalisation and co-evaluation mechanisms. The results of these pilot cases will be widely
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Business and IT-Cloud Alignment using a Smart Socket' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

Business and IT Alignment is important challenge, as we are facing a dramatic change in the way we rely, depend and interact with ICT that influences our everyday life. Although “digital natives” will soon enter the workforce, there is still a huge gap between the business domain and ICT domain in terms of awareness, common understanding or expertise. This hampers the take-off of technology such as Cloud Computing. Hence, we are facing a competition, between global-market players who quicker succeed in changing business into the Cloud to raise ICT efficiency and reduce costs. This is particularly true for SMEs that have started to embrace virtualisation or at best IaaS offers but the exploding and dynamic market of components available on the PaaS or SaaS level demands for expertise and time typically not available at SMEs.Business processes are commodity when defining business activities in human understandable way in form of “sequences of manual, semi-automatic or automated tasks with the aim to achieve the company’s goal”.Previous work in plugIT mapped business processes on static ICT configurations available at a company’s site, assuming ICT is still mainly configured on platform or component level.CloudSocket envisions the idea of “Business Process as a Service”, where domain-specific business processes like employee registration at social insurance, tax report, or legal verification are supported by workflows that optimally match the ICT support for the selected process. The ICT support is expected to be realized by available platforms or software components from PaaS or SaaS platforms.CloudSocket introduces the concept BPaaS that fulfills the business process needs thanks to smart alignment techniques, packages this BPaaS as “extended Cloudlets” that are autonomo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Roll-to-roll technology for the production of high-efficiency low cost thin film silicon photovoltaic modules' to be submitted under Sixth Framework.

assistant: **Abstract**

Photovoltaic (PV) energy will play an important role in the electricity generation of the future. On the medium term it will stimulate the creation of a dynamic new high-tech manufacturing segment. Todays mainstream PV production is based on crystalline Si , whereas amorphous Si deposited on glass in batch processes are entering the mass market with the lowest price per Wp (2.5 Eu/Wp). This project will go a step further and contribute to the extension of the PV market, by developing equipment and new proces ses for the roll-to-roll production of high-efficiency thin film silicon photovoltaic modules. This technology will have decisive advantages for the fabrication of low-cost modules, with unsurpassed capability for building integration. The consortium forme d by equipment manufacturers, module producers, and research institutes will target the following objectives: -Working out of novel concepts, designing new production equipment, and implementing manufacturing systems for roll-to-roll preparation of a-Si/mc -Si modules on plastic and metal foils. This will include systems for monolithic integration of the cells in modules by roll-to-roll laser scribing and screen-printing. -Developing new processes for roll-to-roll pilot-lines and fabricating tandem a-Si/mc-S i solar cells with efficiencies > 11% and modules with efficiencies >10% on flexible substrates, with novel encapsulation processes for product lifetime higher than 20 years. - Blueprint planning of complete roll-to-roll modular production lines with capacities >10 MW/year and with module production costs of 0.5 Eu/Wp, with a benchmarking in terms of life cycle analysis against c-Si silicon and other thin film technologies. The project will not only allow the module manufacturers to implement new e quipment an