RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Epigenome-targeted therapy for cholangiocarcinoma.', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

For > 70% of cholangiocarcinoma (CCA) patients, no curative treatment is available at time of diagnosis and they proceed directly to palliative chemotherapy with virtually 0% surviving at 5 years. Breaking overall cancer trends, CCA mortality rates are escalating among both sexes in the EU, exacerbating this clinical demographic of intractable patients. Recently, a deluge of deep sequencing studies have identified recurrent mutations in epigenetic enzymes in CCA, prompting a turning point in our view of the molecular architecture of this devastating malignancy. Unlike traditional mutations, epigenetic lesions or ‘epimutations’ are intrinsically reversible and, therefore, may comprise an optimal Achilles heel to target for therapeutic benefit. However, to streamline epigenome-driven therapy to the clinic, we first need to clarify molecular and cellular responses to epigenetic manipulation in different CCA models. Accordingly, I have 3 specific objectives of this proposal: i) I plan to carry out a comprehensive in vitro epi-drug screen to determine which enzymatic targets have the greatest anti-neoplastic activity; from this, ii) I will characterize the epigenomic changes that underpin such phenotypic rescue; finally, iii) I will compare the therapeutic effects of the top global-acting epi-drug versus target-specific epigenetic editing (Epi-CRISPR) of the most recurrent epimutation in vivo. Accomplishment of these objectives will improve our understanding of cholangiocarcinogenesis  and also address the unmet clinical need for novel therapeutic targets in this cancer demographic with abysmal prognosis. The project will be supervised by Dr. Jesper Andersen, a world-leading expert in hepatobiliary cancer genomics, and will draw extensively on his expansive patient bio- and
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Exploring home-based support systems for promotion of  food, nutritional knowledge and personal choice', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

Combining work, social obligations and caring for a family in a balanced way has become an important worry of a growing group of European citizens The proposed project will help European citizens to obtain consumer solutions for a hassle-free guidance towards a balanced lifestyle. The project focuses on methods for inferring eating habits in an unobtrusive way and seeks to use this information to provide situated feedback on meal planning and preparation. Throughout all phases of the project a user-centered development (UCD) will be adopted. Since the project is targeting to change people’s behaviour, it is seen as vital to take user needs as the starting point for technology development. The main challenge will be to create solutions that give situated feedback in an enjoyable and engaging manner, leveraging social networking and the collaborative internet (i.e. Web 2.0) to affect behaviour change. The knowledge exchanged and developed in Balance@Home will strengthen both the academic and industrial sectors with knowledge on nutrition assessment, situated assistance for meal planning and preparation and the use of social networking to promote healthy eating.  The partnership between Philips Research and Newcastle University will benefit from knowledge exchange in a number of fields of inquiry. Both partners have significant experience with the development of technology, this expertise is complementary, with Philips having a significant understanding of the development of consumer technologies (and the associated methods) and architectures for pervasive environments, and Newcastle University developing novel design methodologies and techniques to engage in experience-centred design and to exploit new findings in multimodal cognition. Newcastle University will also contr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Future INternet for Smart ENergY' to be submitted under Seventh Framework.

assistant: **Abstract**

The energy sector has entered a period of major change which will continue for many years to come. The increasing proportion of electricity from renewable sources means that the architecture of the energy grid will have to support the distributed, in addition to the centralised, generation of energy and to adapt to a highly volatile supply e.g. from wind and solar generators. From the consumption perspective, electric vehicles will demand new load management patterns in the grids.  At the same time, private and commercial consumers are being encouraged to reduce their energy use and electronics manufacturers are striving to reduce the energy use of their products.  The energy supply will need to evolve into a dynamic system to provide the smart energy infrastructure needed to support society in 2020 and beyond.<br/>Future Internet technologies will play a critical role in the development of Smart Energy infrastructures, enabling new functionality while reducing costs. In the FINSENY project, key actors from the ICT and energy sectors will team-up to identify the ICT requirements of Smart Energy Systems. This will lead to the definition of new solutions and standards, verified in a large scale pan-European Smart Energy trial. Project results will contribute to the emergence of a sustainable Smart Energy infrastructure, based on new products and services, to the benefit of all European citizens and the environment.<br/>As part of the FI-PPP programme, FINSENY will intensively analyse energy-specific requirements together with the other FI-PPP projects, develop solutions to address these requirements, and prepare for a Smart Energy trial in phase two of the programme. The growing FINSENY Smart Grid Stakeholder Group will provide broad visibility of the on-going project wor
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Made in Sweatshops. Worker, technology and Gender (comparison Paris-Shanghai, Late 19th c.-Late 20th c.)' under Horizon 2020.

assistant: **Concept**

Made in SweatShops. Worker, Technology and Gender (Comparison Paris-Shanghai, Late 19th c.-Late 20th c.)Made in Sweatshops (MISS) proposes to study the female workers in the clothing industry through an analysis of workshop techniques and a comparison between two major manufacturing centres: Paris from 1860 to 1900 and Shanghai from 1990 to 2020. By re-evaluating the relationships between bosses, middlemen and female workers, and the links between techniques, qualification, de-skilling and gender , MISS will offer a new way of thinking about female work and the gender of technologies.The objective is to examine how the technical tools of the workshops have affected the lives of women workers in the long term and have contributed to the systematic organisation of the misery of women's work. The comparison between Paris and Shanghai is justified because these two economic centres of the clothing industry are both design and manufacturing centres. At present, the garment industry in the neighbouring province of Shanghai, Zhejiang, is openly modelling its development on that of Paris in the 19th century . New York and London have never been design and manufacturing centres at the same time. This double simultaneity only characterizes Paris and Shanghai. My core hypothesis in MISS is that technology management is a determinant point of this industry. Technological ""progress"" in the clothing industry has very negative effects on the know-how, the misery migrations, the working conditions of the workforce, women's employment and career prospects. It contributes to the impoverishment of creative industries in a context of globalisation . Paris and Shanghai are excellent sites for observing the implementation and reproducibility of an industrial model aimed at de-skilling the
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Low energy consumption LEC-greenhouse' under Fourth Framework.

assistant: **Concept**

The industrial problem to be overcome is the irrational use of energy in Europe greenhouses. Today pot plants are produced in greenhouses with single layer g lass. The greenhouses are heated by oil, natural gas or district heating. Due to the very low insulating value of a single layer glass, the heat consumption per m2 greenhouse is 20 times higher than in a traditional house. A new type o f screen has already been developed which can substitute the single layer glass in greenhouses. If it is possible to combine this screen with a traditional in side energy saving screen, there will be an expected energy saving of approximately 65% compared to a traditional non-insulated greenhouse. This will not only reduce production cost per square meter greenhouse drastically. It will also r educe CO(2) emission in general and as a side effect, make production of vegetables and pot plants in greenhouses stronger, more flexible and cheaper. The means to obtain these objectives is a combination of:-energy saving (screens and heat trap, greenhouse design); -heat storage (water reservoir); -use of renewable energy (solar). The methodology used is a bottom-up development process, starting with design of the main components, combine them into a system, integrate the system by developing the system regulation, and finally make sure it works by testing the total system. The project is a step by step process in five phases, where each phase is evaluated to be sure the development process is on track before the RTD tasks are continued into the following phases. A neigh boring ordinary green house acts as a reference green house with the same plant production at the same time. The innovative content of the project is the iteration and modification of greenhouse state-of-art technology into th
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Optimisation of in-service performance of boiler steels by modelling high temperature corrosion' (OPTICORR) under Fifth Framework.

assistant: **Objectives**

The aim is to develop a LCA for the materials in energy production, particularly for steels used in waste incinerators and co-fired boiler plants. The efficiency, safety and optimal use of boilers, require control of high temperature corrosion of the critical components under high temperatures and pressures. The value of control is growing with the increasing service values for efficient production and needs to use flexible and less cleaner fuels (recycled & ind. waste + biomass).Industrial environment and component combinations will be tested with relevant material specifications for data acquisition to understand the corrosion mechanisms. Computer-based simulation methods are introduced and customised to apply rigorous thermodynamic and kinetic data to empirical systems. The data and simulations are verified with plant tests. The innovative aspects are introducing kinetic models to the calculations and development of user friendly Toolboxes
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'RE-START RENEWABLE ENERGIES STRATEGIES AND TECHNOLOGY APPLICATIONS FOR REGENERATING TOWNS' under Fourth Framework.

assistant: **Concept**

The targeted demonstration project aims at providing the public authorities, the institutions and the professionals of large industrial European Cities with some Exemplary Urban Projects", concerning innovative energy-environmental integration on the city scale.The European cities involved in the RE-Start Project are the following :A.M. Barcelona (ES), Glasgow (UK), Grand Lyon (FR), Torino (IT), Rotterdam (NL), Copenhagen (DK), Porto (PT), Dublin (IE), and St. Petersburg, as observer city. The exemplary projects take into account the following criteria, which have provided a homogeneous background to all City-Projects :- Each RESET City has defined a district where the Targeted demonstration would take place. These sites are generally located in a downtown area (areas to be re-converted to different functions, former industrial sites, etc.) where a regeneration project is starting, with new comprehensive rules.- The area of influence of each City-Project is large enough to allow a strong impact on the decisional mechanisms of the city and a high visibility for the inhabitants.- A mix of functions - housing, tertiary and commercial, institutional, recreational buildings, high-tech industrial settlements - are comprised in Re-Start, representing the complexity of urban situations.The RE-Start Project was started in August 1996.The results are, at the moment, represented by draft or final design of the urban districts and buildings involved in the demonstration, by the organisation of the horizontal and cross demonstration activities, by preliminary assessments at the design stage.In the RESET net WEB site "http//:www.resetters.org" periodic information on the RE-start project advancement is available for the interested professionals, manufacturers and builders.All City-Pr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Development and Commercialisation of a Self-Guided Fluidised Bed Granulation Solution' (SMART-GRAN).

assistant: **Concept**

The proposed Innovation Project aims to develop and commercialise the world’s first Self-Guided Fluidised Bed Granulation Solution targeted at the pharmaceutical, food, nutritional and cosmetics industries. The SMART-GRAN solution will incorporate a suite of Process Analytical Technology (PAT) analysers for the in-process monitoring and closed loop control of the Critical Process Parameters (physical, chemical and moisture properties of the granulate) coupled with soft-sensoring, for obtaining consistent product quality and safety. The ability of the system to confirm cleaning process success between batches will reduce equipment downtime, increase product throughput and lead to increased productivity. Through a cloud-based data management platform, the SMART-GRAN solution will enable historical data to be available for Quality-by-Design process optimisation for gaining resource efficiencies for improved competitiveness. This will enable intelligence-based manufacturing (IbM) concepts which focus on harnessing the complementary power of data, modelling, engineering and IT infrastructure by transforming data into knowledge and ultimately intelligence, to equip industry to move to proactive manufacturing strategies that deliver predictable manufacturing performance. The commercialization of the system will help IPL to secure a position as a global PAT-based solutions provider to the pharmaceutical sector, generating > € 34 M in additional turnover for the company by 2022, and leading directly to the creation of ~58 new high-end jobs through the supply of the system. Roll out to other sectors will treble this potential. Moreover, the competitive impacts upstream and downstream will lead to the creation of up to ~1000 new jobs in Europe.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Service Oriented Programmable smart environments for older Europeans' (SOPRANO), addressing dissemination and exploitation.

assistant: **Impact**

SOPRANO will design and develop highly innovative, context-aware, smart services with natural and comfortable interfaces for older people at affordable cost, meeting requirements of users, family and care providers and significantly extending the time we can live independently in our homes when older. User friendliness and acceptability is top priority for the project - a zero-slope learning curve is to be achieved and interfaces are to vanish" into domestic settings. Large-scale viability in real homes will be demonstrated with 600 users to raise public awareness and accelerate AAL exploitation.SOPRANO extends today's EandAR methods to profoundly change the RTD process, integrating design-for-all - to combat stigma and reap economies of scale in consumer markets - and involving older users in RTD - from requirements, iterative prototyping and usability tests through to 6 month field trials. Research is expected to strongly advance global knowledge in semantic IT, RFID location, remote diagnostics, radar and integration architectures. A new AAL architecture is to support pro-active assistance based on situational analysis fed by user input and local monitoring. Responses are to follow agreed rules and seamess access provided to external professionals. Safety and security is strongly enhanced with adherence to stringent reliability standards. Multiple modalities and dialogue adaptations to cognitive ageing help meet special accessibility and usability needs.The consortium represents all stages in AAL value chains from academic research to quality integration, includes key local authority providers and is coordinated by the market leader in AAL systems provision. A top smart-homes player and advice by top user groups help rapid exploitation of innovative, accepted systems
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Coordination Action for Graphene-Driven Revolutions in ICT and Beyond' in the context of a Seventh Framework call.

assistant: **Objectives**

This Coordination Action aims to prepare a European Flagship project focussed on Graphene-Driven Revolutions in ICT and Beyond" (GRAPHENE). The overwhelming current focus on graphene, discovered by A.K. Geim and K. Novoselov in 2004, is driven by the considerable and tantalizing potential that this material offers in conventional as well as radically new fields of ICT applications.<br/>Europe can play a key role in future graphene-based ICTs provided a long term strategy of transferring knowledge and intellectual property to technological applications is carried out in a coordinated, effective and organized fashion. GRAPHENE-CA will establish a comprehensive scientific and technological roadmap, by taking advantage of the activities of an existing nanoICT graphene working group, contributions of selected industrial partners and key scientists such as the Nobel Laureates A.K. Geim, K. Novoselov, A. Fert and K. von Klitzing. This roadmap will be the basis to develop the research agenda for the subsequent GRAPHENE flagship, which will cover electronics, spintronics, photonics, plasmonics and mechanics based on graphene, and supporting areas such as graphene production and graphene chemistry.<br/>The CA will frame the development of a graphene flagship that is aimed to serve as a sustainable incubator of new branches of ICTs applications, rooted on European scientific excellence and interdisciplinarity (merging physics and chemistry with engineering communities), and providing Europe a strategic instrument and infrastructure for innovation in ICT-related science and applications."