RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Development of TSE therapies based onprion proteinbinding oligosa ccharides' demonstrating excellence, impact and implementation quality for a Fourth Framework call.

assistant: **Abstract**

There is currently no therapy for prion diseases. However, much data indicates that polyanions in general, and sulfated sugars in particular, inhibit prion propagation both in animals and in cultured cells. For instance, the sulfated polysugars pentosan polysulfate and dextran sulfate, the amyloid-binding dye Congo red (CR), and the anthracycline iododeoxyrubicin (IDX) prolong BSE incubation time when inoculated prophylacticaly. Although the mechanisms of action of these reagents remain to be clarified, several lines of evidence connect most of the anti-prion agents with molecules of the heparin family. Heparan sulfate has been shown to be a component of every brain amyloid, and interestingly, the amyloid binding dye CR, a known amyloid stain, is among the most effective anti prion agents. Endocytosis of PrPc, the normal prion protein and precursor of PrPSc is stimulated by sulfated glycans. All anti prion polyanions seem to inhibit the binding of PrPc to heparin sepharose, demonstrating a clear connection between the heparin binding activity of PrPc and inhibition of prion replication. Prion inhibition was tested by several investigators in scrapie infected neuroblastoma cells (ScN2a), a mouse line permanently infected with scrapie prions. In these cells, inhibition criteria is defined as reduction in PrPsc synthesis as well as reduction of prion titer for cell extracts. We propose to initiate a systematic search for more efficient anti-prion agents of the polyanionic class and to determine their mode of action.Our research will focus especially, but not exclusively,on sulfated sugars, and is expected to result in the development of effective anti-prion therapeutic approaches. We will screen both natural and artificial libraries of carbohydrates, as well as other avail
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'THE GENETIC ARCHITECTURE OF SECONDARY SEXUAL TRAITS DURING HYBRID SPECIATION' to be submitted under Seventh Framework.

assistant: **Abstract**

Understanding the genetic basis of phenotypic traits is of fundamental importance in evolutionary and conservation biology, but especially in the field of speciation. Hybrid speciation essentially involves fusion and stabilization of two distinct genomes accompanied by reproductive isolation from the parental counterparts. I will investigate how genetic architecture of secondary sexual traits evolves during hybrid speciation and the consequences this may have on speciation. The Italian Sparrow (Passer italiae) is a stabilized and uniform hybrid taxon that originated from past events of hybridization between two divergent parental species, the House Sparrow (P. domesticus) and the Spanish Sparrow (P. hispaniolensis). The two parental species differ in a number of functionally important traits, including melanin-based plumage coloration. This system provides excellent opportunities to study the genetic architecture of secondary sexual traits, as adult male breeding plumage differs between species. These plumage traits are targets for mate choice in sparrows, and are hence also likely to function in species recognition. More specifically, I will study how the genetic structure of plumage ornamentations in a bird species changes during its origin through hybridization of two parental species. This goal will be achieved by using a combination of cutting-edge methods in quantitative genetics and molecular genetics.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Policies and young people in rural development' (PAYPIRD) targeting Fourth Framework.

assistant: **Abstract**

This purpose of this project is to analyse the effects of policies on young people (aged 16-25) across rural areas of Europe, focusing particularly on their integration into or exclusion from labour markets. The policies considered will be at various geographical levels, including EC (CAP, Social Chapter), national (labour market policies and welfare regimes), regional and local (rural development programmes). As such it is a study of policies affecting rural development. It adopts an analytical approach to identifying the key mechanisms which affect this important and neglected group, who are the future of rural communities. Its focus is the effect of policies on how labour markets and welfare regimes interact with changes in the nature and duration of the youth transition. Because rural labour markets differ from those in urban areas, while welfare assistance may be less available or acceptable, and because 'young people in rural areas are likely to lead a qualitatively different kind of youth from those in towns'(Jones 1992), policies may impact quite differently on young people in rural areas. The OECD has highlighted the need to improve young people's ability to make a transition into the world of work. This research will therefore have important implications for the future of rural development policy. The emphasis is on comparative case studies of how policies impact on real-life conditions, and on linking personal narratives with macro processes of economic, social and institutional change. No such comparative studies have been conducted across rural areas of Europe, and our knowledge of how policies affect young people in rural Europe is small. Yet rapid changes affect their lives as a result of European integration, CAP reform, economic and social restructuring
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'DESign of bio-based Thermoset polymer with rEcycLing capabiLity by dynAmic bonds for bio-composite manufacturing'.

assistant: **Objectives**

ESTELLA is an ambitious initiative that proposes an innovative solution to improve the recyclability of low-recyclable materials: thermosetting composites. To this end, ESTELLA will work on the design of novel bio-based epoxy resins with inherent recyclability capabilities thanks to the introduction of Covalent Adaptive Network (CAN) in the original epoxy structure. CAN will provide the thermosetting epoxy resin with the ability to respond to certain stimulus that changes the state of its microstructure and thus, the ability to be reprocessed/re-polymerized (return to original monomers and fibres). A similar strategy will be applied to existing fossil-based epoxy formulations. In this way, the thermoset can be reprocessed or re-polymerized into new products and the fibres can be recovered as well. In addition, fibres of renewable origin will be used as reinforcement to manufacturing thermoset composites. ESTELLA research will address recycling techniques of any nature (chemical, biological and mechanical) to guarantee that the materials developed during the project can be successfully separated into their components in a safe and cost-effective way, hence maximizing the revenue of recycling activities. The validation of the developed recyclable materials will be carried out through economically and environmentally efficient manufacture processes (out-of-autoclave). Thus, new bio-composites will be designed and developed based on the premises of improving recyclability while meeting the demands of different sectors such as construction and leisure/mobility. Also, extensive work will be carried out to leverage the industrial application of the technologies and materials developed, taking into account safety, techno-economic, regulatory and intellectual property aspects.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Acoustic Intelligence and AI, the Next Frontier. Listen, detect, predict.'.

assistant: **Objectives**

Predictive Maintenance (PdM) is a maintenance technique, based on the monitoring of equipment conditions combined with different sets of real-time analytics to achieve cost savings by predicting failures, and detecting and responding to unanticipated equipment or process degradation. However, there are a few key factors hindering progress and digitalisation of the Industry 4.0: 1) Current estimations state that worldwide, there are 60M machines in factories, of which 90% are not connected; and 2) Current technologies are not appropriate: they are complex to install, requiring the maintenance team to reach to each machine separately; their inability to monitor a combination of machines that work in sequence; the high costs since several sensors are required for the measurement of the different aspects of the machine; ultimately leading to late detection.Sound Health is an acoustic data acquisition 24/7 system to monitor machinery for predictive maintenance (PdM). The system gathers high resolution data, detecting and predicting when maintenance is required, providing valuable reporting and insights, and becoming more efficient and competitive. Sound Health is the only Cloud based SW and HW platform for digitisation, visualisation and PdM of machines based on PLC parameters and additional acoustic sensors. Offering also PdM solution based on the large database it collects.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Understanding nitrogen metabolic interactions in mixed anammox-based microbial communities' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

Improving current biological wastewater treatment plants (WWTPs) towards more reliable and resource-efficient solutions is a priority of the EU (Water Framework Directive). Successful biological treatments rely on the concerted activity of different microorganisms and thus optimized microbial community engineering strategies are required to achieve this goal. Processes based on anammox bacteria hold promise to reduce the energy and resource expenditures of WWTPs. However, our current knowledge of the different microorganisms involved and the environmental factors regulating their interactions in anammox-based microbial communities remains limited. The MixAmox project aims at advancing our fundamental understanding of the metabolic interactions and their implications for process performance in these communities through a multidisciplinary approach based on theoretical and experimental methods combined with cutting-edge molecular techniques and stable isotopes. The obtained results are expected to foster the implementation of anammox systems. Moreover, the developed methodological framework will be directly applicable for the study of any natural or engineered complex microbial community. Hosted at TU Delft, the researched (ML) will develop a strong theoretical background in thermodynamic analysis and mathematical modelling of microbial communities. He will also learn how to design and conduct short and long-term incubations, combined with stable isotopes, targeting the study of metabolic interactions and microbial competition dynamics. ML will spend the secondments at Aalborg University where he will be trained in high-throughput sequencing technologies for the phylogenetic and functional characterization of complex communities. This unique combination of expertise will
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Scaling-up quantum computers with quantum memory links' (SQOUT) targeting Horizon Europe.

assistant: **Abstract**

Fully achieving the many promises of quantum computing will require dramatically scaling up the number of quantum bits (qubits) that quantum computers manipulate. The only way consists of interconnecting several mid-sized quantum processing units (QPUs) in clusters to effectively multiply qubit counts.Welinq is building the essential interconnection technology to support modular quantum architectures by combining the world’s best quantum memory and novel networking protocols to construct “quantum links”. Our unrivalled on-demand storage-and-retrieval of quantum light enables us to efficiently entangle separated QPUs, enabling larger and more powerful quantum computers.SQOUT will ensure the adaptability and scalability of Welinq’s full-stack solution to drive the global market adoption of our turnkey quantum links. Our internationally renowned team has unsurpassed technical expertise alongside quantum business commercialization experience. With EIC support, Welinq will make the interconnection of QPUs a reality and secure Europe’s quantum industry leadership.


**Keywords:** quantum memory; quantum interconnection; quantum computing; cold atom ensembles; quantum technology; quantum devices
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Spin systems with discrete and continuous symmetry: topological  defects, Bayesian statistics, quenched disorder and random fields'.

assistant: **Concept**

The main goal of this project is to understand the geometry of the deeply influential topological phase transitions which were discovered in the 70's by Berezinskii, Kosterlitz and Thouless. The archetypal example of such phase transitions arises in the 2d XY model in which topological defects, called vortices, behave very differently at small and high temperature. The mathematical understanding of this rich phenomenon goes back to the work of Fröhlich and Spencer in the 80's and involves the 2d Coulomb gas. This project is aimed at analyzing this phase transition through the prism of random fractal geometry by associating natural percolating sets to the XY model whose behavior will depend crucially on the temperature. One constant source of inspiration will be the deep geometric content and powerful probabilistic methods  gathered over the last 20 years for celebrated discrete symmetry models such as 2d critical Ising or percolation. New tools will be brought in, among which the recent works of the PI with Sepúlveda which analyze the 2d Coulomb gas and make connections with Bayesian statistics.Since the early days of topological phase transitions, topological defects have been found to arise also in some discrete symmetry spin systems as well as in Abelian lattice gauge theory in 4d. This project will explore the geometry of these by making several novel and fruitful connections with the dimer and Ising models.The new connections made with statistical reconstruction and Bayesian statistics will give access to the even more fascinating and least understood world of spin systems with non-Abelian (gauge-)symmetry. Finally, we shall investigate the mechanisms which relate the microscopic background noise with the large scale structures it induces in the contexts of Quant
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'A machine learning conservation apPROach to evaluaTE extinCTion risk in freshwater biodiversity' in the context of a Horizon Europe call.

assistant: **Objectives**

Accurate assessments of species’ contemporaneous extinction risk (CER) are vital to quantifying the current biodiversity crisis and prioritising conservation efforts. However, the most comprehensive global dataset of CER - the IUCN Red List of Threatened Species - is taxonomically biased due to the lengthy assessment process, leaving understudied taxa, such as those in freshwaters, under no formal PROTECTion. Prediction-based models based on novel machine learning methods enable large-scale automated assessments of CER, reducing data deficits rapidly. The main goal of this project is to identify predictors of CER in freshwater habitats, focusing on the largest family of freshwater gastropods, the Hydrobiidae. First, we will use a deep-learning approach to automatically predict the Red List status of hundreds of hydrobiid species from multiple regions and ecosystems that have not been evaluated yet, basing the predictions on ecological and macroevolutionary data. Second, high-throughput sequencing methods will be conducted for the first time in this taxon to compare microevolutionary diversity with population trends derived from long-term field surveys. Last, by establishing a multifactorial prediction-based method, the project will identify which features (ecological, macro-, microevolutionary or all) are meaningful to inferring CER in freshwater organisms. The implications of this proposal are threefold and relevant to scientific, technological and societal concerns. Our findings may provide a basis for comparing predictors of CER across taxa. They will also open up a more integrative framework for conservation actions, moving beyond species-by-species categorisation. Focussing on the ""Natural Resources, Agriculture & Environment"" area from HORIZON 2021-2027, this pr
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Photon induced Spintronics on Hybrid Organic-inorganic Perovskites: Effect of Rashba Spin-Orbit Coupling' (SpinPVK).

assistant: **Innovation**

In the Last few years, hybrid organic-inorganic trihalide perovskite (HOIP) solar cells an imperative and motivating research field and this is an interesting multifunction material owing to their high carrier mobility, semiconducting properties, and extremely high performance in solar cells (achieved solar power conversion efficiency is >25%). On the other hand, a numerous theoretical and experimental research were done and going based on perovskite materials. But, till the perovskite materials is a promising material for further development in photovoltaics and optoelectronics devices. However, beyond the photovoltaic applications, HOIP’s electron spin characteristic behaviour have not been studied in detail and the reports are very limited. In this SpinPVK project, to demonstrate the effect of spin states in perovskite materials photovoltaic and optoelectronic devices, due to the spin-orbit coupling (SOC). Also, to study the photon induced spin-polarized carrier injection into HOIP’s for spin light emitting diode and spin-valve devices. we will switch the photoexcited charge carrier polarization from linear to circular polarization by the effect spin induced band shifting, which will be increase the photocurrent and photovoltage in HOIPs photovoltaics.  In addition, we will validate the influence of perpendicular magnetic field on HOIP by photon induced spin orientation and long life time photocarrier for high efficiency perovskite solar cells (PSCs). Overall, this SpinPVK project aims to develop and fabrication of HOIP based spintronic devices and which will be delivered in-depth knowledge about spin-related properties such as SOC, Stark effect, magneto-optical effect, polarized light-related effect, complex light emission and spin/photon induced photovoltaics. Also