RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Turning the concept of magnetocaloric cooling on its head' (2014-2020).

assistant: **Concept**

Twenty years of research in magnetocaloric materials has failed to provide the necessary breakthrough that will lead to a commercial realisation of this technology and satisfy the urgent global need for more efficient refrigeration. We strongly believe that this is a result of looking in the wrong direction. The cool innov project will achieve this breakthrough by rethinking the whole concept of caloric cooling. We are rejecting the conventional idea of squeezing the best out of magneto-structural phase-change materials in relatively low magnetic fields, and instead we introduce a second stimulus in the form of pressure so that we can exploit, rather than avoid, the hysteresis that is inherent in these materials. The hysteresis will allow us to lock-in the magnetisation at saturation as the magnetising field is removed, so that magnetic fields persisting over a large area will no longer be required (instead, we can use a very focused field), and then demagnetise the material in a second step with an applied stress, enabling us to extract a lot more heat. In this case we only need to apply the magnetic field to a small volume of material, making it a completely new application for commercially available, high-temperature, YBCO-type, bulk superconducting permanent magnets. With the high-field, multi-stimuli approach proven, we will develop new magneto/mechanocaloric materials that match the new high-field, hysteresis-positive approach and start to fabricate novel heat-exchanger structures using additive manufacturing, so that we can combine a mechanically sound heat exchanger having a complex geometry with locally tailored, magneto/mechanocaloric properties. The success of cool innov will be game changing. We are being very ambitious in targeting a revolution in cooling t
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Interfacing organic electronics with biological cells' (BIOORGANICS).

assistant: **Concept**

The emergence of organic electronics – a technology that relies on carbon-based semiconductors to deliver devices with unique properties – represents one of the most dramatic developments of the past two decades. A rapidly emerging new direction in the field involves the interface with biology. The “soft” nature of organics offers better mechanical compatibility with tissue than traditional electronic materials, while their natural compatibility with mechanically flexible substrates suits the non-planar form factors often required for implants. More importantly, their ability to conduct ions in addition to electrons and holes opens up a new communication channel with biology. The experimental work will explore the fundamentals of communication at the interface between conducting polymers and living cells. Specifically, this project will examine the merits of organic electrochemical transistors (OECTs) as the “input” devices from the cellular world: devices that translate ionic fluxes from electrically active cells into electrical signals in the transistor channel. The fellow will seek to understand the mechanism behind recording the electrical activity of cells with OECTs and to use this knowledge to design OECTs that record action potentials in an efficient and chemically-sensitive manner. Through collaborations with the microelectronics industry and partners in life sciences, the applications of OECTs in biomedical implants and sensors will be exploited.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Physics of Microbial Motility'.

assistant: **Innovation**

PHYMOT comprises academic and private partners, spanning eight EU countries in a collaborative research platform in the topical and fast growing area of the biophysics of microbial motility. Through PHYMOT leading European scientists in the field of microbial motility will deliver an interdisciplinary research and training program for the next generation of outstanding researchers, with excellent opportunities to move across theory and experiments, industry and academia, fostering inter-sectorial exchanges of individuals and ideas. The scientific objective is to understand the physics of cell motility, from single cells to collective behavior. Cell swimming underpins a wide range of fundamental biological phenomena from microbial grazing at the base of the food web, to parasitic infections, and animal reproduction. Research on cell motility is booming driven by new experimental, theoretical, and numerical tools from mathematics, engineering, and physics. Advances have provided fundamental new insights, from the constraints on single-cell propulsion to the optimality of responses to environmental clues, and promise new technologies based on control of microbial movement. PHYMOT’s impact will be broad. The overarching goal is to train young researchers at the interface between physics, biology, and engineering, creating future leaders to face core challenges of modern society: food production, disease treatment strategies, sustainable and ecological development. Their research and future careers will have a significant impact on a wide spectrum of important fields, such as medicine, biotechnology, and environmental microbiology.


**Keywords:** micro swimmers,motility, microorganisms, eukaryotic flagella, chemotaxis, collective dynamics/swarming, biofilms, environmental b
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Migrant workers across European Labour markets. Mobility, citizenship and urban resources in the pre-industrial cities - XVIth-XVIIIth century' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

The project focus on mobility related to one of the central element of every society: labour market. One of the reasons more frequently adduced at the base of the choice of emigrate is the research of a job. Many scholars have analysed migratory chains and professional specializations of ethnic groups , stressing as immigrants communities were able to conquer relevant places on the labour market. Therefore, the fact that immigrants were not secondary actors on the labour market stage is ascertained, and some studies point out as many foreign people could reach a prestigious position in the city of arrival . Pre-industrial cities and their labour market, in fact, seem to be quite open to foreigners: as many scholars have underlined , modern towns did not divide their inhabitants between citizens and not, but rather between stable and temporary inhabitants. This feature of openness is at the base of the strong circulation of women, men, wealth and knowledges between pre-industrial European countries. In all the major cities we can find foreigners communities, which are frequently well inserted in the local labour markets, to whose functioning they are an indispensable part. Migrant workers mobility traces therefore the lines of a working common space, an European Labour Market where women, men, wealth and knowledges move along, a common space kept together despite its differences and its largeness by the networks between different (and sometimes far) cities, built up and kept in time by its migrant inhabitants.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Novel Processing Technology for Manufacturing  Low- fat Mozzarella-type Cheese with Superior Performance in  Ready Meals' in the context of a Seventh Framework call.

assistant: **Objectives**

Our novel concept is to develop a low-fat cheese processing technology to enable the production of low-fat Mozzarella-type ingredient cheese with superior texture, flavour and melting qualities. The newly developed low-fat cheese will be suitable for use in pizzas, ready meals, fast food, sandwiches and salads. Our primary target markets are the industrial cheese sector for chilled and frozen pizzas and ready meals. We will also target the retail and foodservices sectors.We propose to develop a Mozzarella-type cheese with <3% fat which is a significant improvement on the currently available 5% fat cheese. Reduced (12% fat) and lower fat content Mozzarella-type cheese are currently available on the market but with very poor qualities of flavour, texture and melting, widely prevents them from consumer acceptance. Therefore we will introduce new innovative starter cultures for improving the flavour and texture of low-fat Mozzarella-type cheeses and optimize appropriate processing conditions of temperature, pH, milk fat and casein-to-fat ratio in the milk. Furthermore, we will develop an innovative oil coating process for improving the meltdown of the low-fat cheese after it is shredded in the meal in preparation. Based on the scientific findings of the coating process, we will then develop an oil coating device which will successfully coat cheese shreds.We will enhance our knowledge of starter cultures and oil coating of cheese and hence provide the end consumer with a cheese displaying desired texture, flavour and melting profiles. We strongly believe that our technology will help the European cheesemaking industry which is facing the threat of losing a significant proportion of its market  as  a result of European legislation which calls for limiting saturated and trans
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'A bioinformatics and systems biology approach for the functional analysis of a growth-regulating MAP kinase pathway in Arabidopsis' (ARA-MKK-D).

assistant: **Concept**

This proposal contains fundamental science, but within one of the central aspects that make plants of vital importance for humanity: their growth and development. It is increasingly clear that biomass is one of the few sustainable energy alternatives. The mitogen-activated protein kinase (MAPK) phosphorylation cascades are conserved signalling modules in all eukaryotes and have pivotal roles to regulate cell division and cell growth in animals but such roles in plants are just emerging. Specifically, in my work I recently discovered that group D MAPK kinases potentially regulate plant growth and development. Within this project I propose to focus on MKK9, because it is also stress induced, and bioinformatics analysis shows co-regulation with genes important in growth and environmental adaptation. A close collaboration between the School of Biological Sciences, and the Computer Sciences at Royal Holloway, University of London, will enable me to build a novel system's biology approach to reach my goals.My work program is designed around six modules;1. molecular genetics studies of MKK9 by analysing insertional mutants, RNAi and over-expression lines,2. detailed phenotypic analysis of these lines3. genome-wide transcriptomics with inducible gain of function mutant forms to find downstream targets,4. bioinformatics analysis of the transcriptome data that we obtain, and the public databases to find candidate target genes, and coregulated genes,5. high-throughput functional analysis of the MKK9 signalling pathway by a cell transfection system and promoter reporter gene readout and finally6. model building that utilise gene antology (GO) terms and computer language, which will allow to make predictions and plan further experiments on the whole plant level towards the goal of a
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'Pushing from within: Control of cell shape, integrity and motility by cytoskeletal pushing forces'.

assistant: **Objectives**

The ability of cells to sense environmental cues and respond to them by adjusting their shape and motion is fundamental for biological processes ranging from animal development to disease. Much is known about how cells sense and respond to the geometry and mechanics of their environment by adhering to and pulling on the substrate. However, recent studies demonstrated that cells also strongly depend on non-adhesive interactions with the environment and that they probe, sense and deform their surroundings by pushing into them.The goal of this project is to address the mechanisms controlling cell shape and cell-substrate interactions via pushing forces.We will focus on three levels of cell organization:1. Nanoscale pushing: We will investigate how cells locally sense and respond to obstacles without adhering to them and quantify the associated forces. Using micro-engineered substrates and tissue mimics, we will molecularly and biophysically dissect, biochemically reconstitute and theoretically model the interface between an obstacle, the plasma membrane and the actin cortex.2. Mesoscale cell mechanics: We will investigate how actin, microtubules and intermediate filaments collaborate to generate and extend mesoscopic cell protrusions that push by adhesion-independent mechanisms. We will combine cell biological experiments and optogenetics with modeling and bottom-up reconstitutions.3. Global force balance: We will examine adhesion-independent mechanisms that allow a cell to coordinate competing protrusions, maintain its integrity and translocate in complex environments. Using biophysical measurements and local molecular perturbations, we will test models of long-range communication within cells.Our work will provide new fundamental insights into biological and physical pri
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Computational and Experimental Enzyme Engineering for New Polymers' (COMENZE) under Horizon Europe.

assistant: **Objectives**

Polymeric materials are ubiquitous in our daily lives but they have a predominantly fossil origin, with low degradability at their end-of-life. Transitioning to a circular polymer economy requires a rethinking of the entire value chain, from the raw materials, tools, and processes used to polymer design degradation and recycling. Enzymes are eco-friendly and sustainable tools that tackle many industrial applications. However, biocatalysis in the polymer field remains mostly unexplored due to i) enzymes’ high cost and low stability under reaction conditions, ii) enzymes’ inefficiency in converting bio-based monomers into cost-effective building blocks, and iii) lack of knowledge in key enzyme-polymer interactions that can control the final polymer performance and degradability features. Computational tools have shown immense power to revolutionize the field of enzyme engineering in a time and cost effective way. However, there is currently a clear lack of researchers combining computational and experimental skills, capable of determining future directions for the optimization of biocatalytic processes for the sustainable molecular design of polymers. To foster the transition to a bio-based polymer industry, COMENZE aims to develop enzymatic strategies for improving the eco-design and development of future sustainable polymers. This will be achieved by combining cutting-edge computational and experimental approaches for enzyme discovery and engineering through in-silico modeling, simulation, and translation of results into wet labs to validate enzymatic reactions. COMENZE will train the next generation of researchers by equipping 10 DCs with the skills to revolutionize the polymer circularity by delivering new optimized enzymes and bioprocesses, newly identified bio-based
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Exchange Programme to advance e-Infrastructure Know-How' (EPIKH) targeting Seventh Framework.

assistant: **Abstract**

Europe is heavily investing to create a continental e-Infrastructure based on Grid technology in order to turn the vision of a European Research Area (ERA) into reality.  Nowadays, e-Science and e-Infrastructures are considered key enablers of the progress and sustainable development of a country and are concrete means to address the problems of the “digital divide” and the “brain drain” which are endemic in large parts of the world. In the context of its Framework Programmes, EC has already co-funded several projects to stimulate and foster e-Science and Grids well outside its borders and in several parts of the world such as Asia, Latin America and the Mediterranean. However, the adoption of the “Grid paradigm” and the effective usage of e-Infrastructures require a capillary activity of knowledge dissemination and training to help scientists to make use of distributed computing capabilities for/in their scientific applications. The strategic aims of the EPIKH project are to:  • Reinforce the impact of e-Infrastructures in scientific research defining and delivering stimulating programme of educational events, including Grid Schools and High Performance Computing courses; • Broaden the engagement in e-Science activities and collaborations both geographically and across disciplines.  These ambitious goals translate into the following specific actions: • Spreading the knowledge about the “Grid Paradigm” to all potential users: both system administrators and application developers through an extensive training programme; • Easing the access of the trained people to the e-Infrastructures existing in the areas of action  of the project; • Fostering the establishment of scientific collaborations among the countries/continents involved in the project.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Building a platform for enhanced societal research related to nuclear energy in Central and Eastern Europe', explaining its relevance to EU policy priorities under Seventh Framework.

assistant: **Impact**

The objective of PLATENSO is to provide a proposal towards establishing the legal base for a European Entity on Socio-Economic matters linked to nuclear technology and to develop recommendations for research strategies in PLATENSO countries. Thereby the capabilities of research institutes in Central and Eastern European countries to take part in EU research with respect to governance, social and societal aspects is enhanced.Initially, lessons learned from earlier projects, what is the state of knowledge in societal, social and governance issues, are reviewed and summarized. The research infrastructures within which project activities and future research are to take place are mapped and efforts are made to make sure research actors frame their approaches broad enough. Research strategies are formed for research in governance, social and societal issues in which participation in EU programmes is an integrated part. The strategies are tested with case studies to make sure they are feasible to implement. A number of networking activities are carried through as a major step toward actual foundation of the strategies in PLATENSO countries.  In each country a PLATENSO partner will take responsibility for building a network of research institutions in its respective country.Establishment of the legal base for a European Entity on Socio-Economic matters linked to nuclear technology has potential to overcome the barriers that still exist for taking them fully into account and to make the awareness of the social and political challenges to come to action. On the basis of exploratory studies focusing on Central and Eastern Europe and contacts with relevant stakeholders in all EU, the project will analyze main aspects with regard to the implementation of the entity (organization, le