RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Improving Renewables Penetration Through Plug and Play Microgrids' (RePower).

assistant: **Innovation**

For Africa to meet its 2030 SDG7 targets and ambition of attaining energy-for-all by 2040 and climate neutrality by 2063, the proportion of renewables in the current energy mix needs to be dramatically improved through robust and effective technologies, sustainable business models, a skilled technical workforce and an enabling regulatory environment. RePower will contribute to these efforts by demonstrating and validating a modular and scalable plug and play (PnP) microgrid system based on photovoltaics (PV) and biomass combined heat and power (BCHP) augmented with a battery energy storage system (BESS) and an intelligent energy management system (EMS), and by providing tools, processes and a roadmap to replicate the installation of this modular plug-and-play microgrid system at any other location. The modular and scalable RePower microgrid system will build upon the Solartainer, an existing and containerised PV-BESS solution that has already been successfully piloted by project partner, AGT, in 21 locations empowering 25,420 customers in remote off-grid locations and providing 934 SMEs with power in Mali, Niger and Chad. The new Solartainer RePower combined with a unique BCHP solution will have the capacity and flexibility to provide distributed, affordable, reliable and stable electricity as well as heat and cooling to off-grid communities in Senegal, Niger and Madagascar. Compared to the average PV-based microgrids currently on the market for Africa, the RePower setup including BCHP will improve the renewable energy generation capacity of the existing plants by over 50% while also reducing the unit cost of electricity by about 60 % – 70 % allowing consumers to extend electricity usage to the productive use of energy (PUE), such as farming, water pumping, food process
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Research development of innovative construction uses for cardboard tubes' under Fifth Framework.

assistant: **Concept**

Cardboard tubes have great potential for structural and component uses in the construction industry; they are light, very strong and 100% recyclable. A British- Italian consortium proposes to make use of an Exploratory Award to carry out the necessary research for a CO-OPERATIVE research project to fulfill the potential of cardboard tubes in this area. Additional information on structural properties, waterproofing and connection methods is required. ECOCARD will build up a database of existing uses of cardboard tubes, and research the feasibility of new designs and processes. It will design, manufacture and evaluate proto-types for uses such as columns, partilioning and temporary housing, and provide test results for inclusion of cardboard in construction standards. Additional SMEs will be sought among manufacturers, designers and end users to strengthen the partnership.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'High-resolution imaging of cold and controlled molecular collisions using recoil-free resonance-enhanced multiphoton ionization detection schemes', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

The study of collisions between cold molecules is currently an area of intense research interest, which opens many new possibilities to study the most fundamental aspects of molecular interactions and brings the goal of manipulation and control of chemical reactions within reach. Moreover, fully understanding of cold molecular collisions could shed new light on some important puzzles in the Earth’s atmospheric and interstellar chemistry. However, to date, the study of cold molecular collisions remains largely unexplored, due to a huge challenge in the experimental approach. A new crossed-beam scattering experimental method combined with a multistage Zeeman decelerator and recoil-free resonance-enhanced multiphoton ionization (REMPI) detection schemes proposed in this project allows us to investigate the dynamics of cold and controlled molecular collisions with unprecedented resolution in a new, previously inaccessible, regime. The focus will be on addressing some valuable and intriguing scientific problems relevant to atmospheric and interstellar chemistry. The objectives of this proposal will be to observe and understand scattering resonances in low-energy inelastic scattering of He with NH and ND, find a solution to the long-standing “interstellar oxygen problem” in the barrierless radical-radical reaction of O with OH, and test the validity of the statistical treatment of ozone formation in atmospheric chemistry models in the exchange reaction of O with molecular oxygen. The combination of the scattering data that will be obtained and the high-level quantum scattering calculations will provide a critical and unique test for current models of chemical processes occurred in the Earth’s atmosphere, interstellar space. The proposed research will be a major breakthrough i
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Health, Cognition, Family, and Employment among Men' (HOMME).

assistant: **Innovation**

Men are more likely than women to die prematurely, and a great deal of men’s excess mortality is preventable. Improving men’s health and cognition is not only critical for achieving gender equality, but also for enhancing and extending men’s potential to contribute to their families, the labour market and society as populations grow older. HOMME studies how men’s (changing) family and working lives influence their health and cognition. Men’s family and working lives are changing: Men now lag behind women with regards to tertiary education; female labour participation has increased while male labour participation has slightly decreased. Men are more apt to lose their job due to technological change. Male childlessness has risen dramatically, much more than female childlessness; in many Western countries, one out of four or almost one out of three men are now childless at age 40. Fathers are participating more in childcare, and men have partially lost their role as family “breadwinners”. So far, insufficient research has examined the consequences of these changes on men’s health and cognition. HOMME capitalizes on the richness of Norwegian population register, survey, and genetic data to examine how men’s (rapidly changing) family and working lives are related to their health and cognition across adulthood, as well as across cohorts, periods and between communities. We focus on young adulthood and midlife – the life period most characterized by family transitions and work experiences. We examine cohort and period differences, men’s work-face interface, the male breadwinner model and fathers’ participation in childcare, and disentangle selection and causality. Our data covers genes; parents, (former) spouses and partners; self-reported, clinical, and register measures of h
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Regulation of osmotolerance molecular breeding for improvement of plant drought, salt and cold stress tolerance' (ROST) targeting Fifth Framework.

assistant: **Abstract**

Drought, salt and cold are the most important factors limiting plant productivity of southern and northern European lands. Molecular breeding to improve plant stress tolerance is an important target for agro-industrial exploitation. Our objectives are to identify new genes that play a key role in the control of plant stress responses in Arabidopsis and to transfer this knowledge into practical breeding of crop and tree models. We will: 1) Identify key regulatory genes and screen for mutations using forward and reverse genetics. 2) Define the role of osmoprotective proteins by using biochemical and transgenic approaches. 3) Validate the use of regulatory genes in resistance breeding programmes to improve stress tolerance in tomato and poplar.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Development of a Sustainable, Low-cost and Long-term Lab-on-a-Chip colorimetric paper-based sensor for saxotoxin quantification in water and seafood' under Horizon Europe.

assistant: **Concept**

Dr. Sara Santiago Malagón will conduct a fellowship focused on developing a Lab-on-a-Chip (LOC) colorimetric paper-based device for point-of-need (PON) detection of saxitoxin, a toxin produced by cyanobacteria and certain microalgae. The primary objective of this project is to mitigate cyanobacteria contamination in stagnant water and harmful algae bloom (HAB) occurrences in seawater, which can lead to the death of marine species and the poisoning of animals and humans. We aim to validate an accessible, eco-friendly, cost-effective, and user-friendly technology that can be extended to detect and quantify various biotoxins relevant to public health and the environment. The driving force behind this project is the current gap in the development of portable sensor systems for environmental applications in marine ecosystems, freshwater, and seafood quality control, all without the need for specialized equipment.In addition to the research that will help control and prevent damage to the ecosystem and preserve species diversity, the methodology and materials presented are sustainable and environmentally friendly, aligning with the project's environmental commitment. Furthermore, the materials used (silk) will facilitate the stabilization of biomacromolecules required for the detection and quantification of saxitoxin, enabling the creation of long-span sensors. Ultimately, the end goal is to validate that the colorimetric device, designed as a toolless system, can be operated by minimally trained volunteers (end users) through a user-friendly mobile application interface, even if they do not possess specialized knowledge or skills. These individuals play a crucial role in environmental preservation and prevention efforts.This grant would offer the applicant the opportunity to
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Terahertz Photonics for Communications, Space, Security, Radio-Astronomy, and Material Science' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

The overarching objective of TERAOPTICS is to provide high-level training in the field of THz Photonics to a new generation of high achieving early stage researchers to provide them an inspiring research program and intellectual, scientific, technical and transferable skills trainings to enhance their career opportunities in academia and industry and to create the new generation of excellent, creative and risk-taking researchers and engineers. This goal will be achieved by a unique, internationally renowned, interdisciplinary and inter-sectorial network of academic and non-academic beneficiaries and partners providing both formal (workshop-style) and informal (hands-on) research training in a most stimulating professional environment, non-academic placements and scientific conferences.


**Keywords:** Photonics, Terahertz, Integrated Photonics
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Peptide-functionalized POMs as biofilm disruption agents: searching for synergy in bactericidal materials' (PePiPOM) under Horizon 2020.

assistant: **Objectives**

Antimicrobial resistance is an increasingly serious threat to global public health and immediate action must be taken to prevent its ever-increasing spread. One approach to overcome this problem is the development of new materials and coatings with bactericidal action; in particular those which tackle biofilm formation specifically. By inhibiting the growth of biofilms, bacteria become more sensitive to treatment and resistance diminishes. The applicant has designed PePiPOM to develop peptide-functionalized polyoxometales (POMs) that possess synergic bactericidal activity. The PePiPOM materials combine the anti-aggregation activity of POM molecules (key to tackling growth of biofilm matrix) with the bactericidal effect of POMs + antimicrobial peptides (to rupture bacterial cell membranes and/or internalise and destroy bacterial cells). Central to the success of this proposal is a novel approach for the synthesis of POM-hybrids whereby an “on-POM polymerisation” will be used to produce peptide-POM hybrids. The design of the antimicrobial peptides will also play a key role in the success of the project, since they will provide the required properties for an improved and synergistic activity. The resulting PePiPOM biofilm inhibitors will be tested for both their anti-aggregation and antibacterial activity, and the most effective candidates will be evaluated as anti-biofilm agents on plastic and metal surfaces. The fundamental academic aspects of these results will be of interest to the chemistry and microbiology communities and their application of great relevance to industry and the general public. The PePiPOM MCSA will open new research horizons for hybrid materials with synergic antimicrobial properties, but also importantly, will offer a real boost in the career develo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Neuroimmune activation as a novel therapeutic approach for IBD' in the context of a Horizon 2020 call.

assistant: **Objectives**

NeurIMM has been designed to investigate the commercial and technical viability of a novel, targeted therapy for Inflammatory Bowel Disease (IBD), based on a recently uncovered signaling axis between intestinal type 3 innate lymphoid cells (ILC3s) and enteric glial cells. This discovery by the team of Prof. Henrique Veiga-Fernandes in the ERC CoG grant 647274 ‘GliaInnateSensing’ was recently published in Nature (Ibiza et al, Nature 2016). NeurIMM proposes the use of a glial cell-derived immunomodulator to restore intestinal homeostasis, by inducing a tissue protective immune response. Importantly, this novel therapy will also promote tissue healing to reverse immune-cell mediated tissue damage, leading to improved outcomes for the patient. This could have major implications for patients suffering from IBD. In addition, this approach also has potential as an effective therapy against cancer, (pediatric) gastroenteritis, and other inflammatory disorders.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fifth Framework proposal for the project 'Impact of natural and trawling events on resuspension, dispersion and fate of pollutants (INTERPOL)'.

assistant: **Objectives**

The Mediterranean coastal zones experience intense trawling activity and severe storm surges inducing significant resuspension-release of nutrients, pollutants and toxic elements. Due to their oligotrophic character the resuspension processes are expected to play a key role in the carbon, nutrients and pollutants recycling in the Mediterranean coastal ecosystem. INTERPOL project, bringing together complementary expertise and know-how, in an unprecedented way, will provide new and unique data towards the understanding of the environmental impact of resuspension processes in the Mediterranean coastal ecosystem. It will also help to constrain and to identify the complex routes of pollutants transfer within the marine system. These are important steps towards a better assessment of the marine cycling of natural and anthropogenic substances, including toxic ones, and thus towards a better protection of the Mediterranean from pollution.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Forward and reverse genetic approaches to understanding sphingolipid metabolism and functions in plants using the model bryophyte Physcomitrella patens' (SMFP) targeting Horizon 2020.

assistant: **Abstract**

Sphingolipids are essential lipids that are ubiquitous among eukaryotes. Plants produce structurally diverse sphingolipids that are involved in many processes, including maintenance of plasma membrane integrity and microdomain formation, cell growth and division, polar secretion, and programmed cell death (PCD) signalling. They have primarily been investigated in Arabidopsis thaliana, for which an extensive genetic toolkit has been available for decades. Genome sequences and tools for genome editing are now available for a wide variety of species, offering a better understanding of metabolic and functional diversity, and enabling study of evolutionary history and ancestral functions. The bryophyte Physcomitrella patens is an early-diverged land plant and a relatively new model organism. Preliminary work revealed a unique sphingolipid profile for Physcomitrella, and diversification of gene families associated with the biosynthesis of glycosylinositol phosphorylceramides (GIPCs), the most abundant and diverse class of sphingolipids in plants. The precise functions of GIPCs have been challenging to study in Arabidopsis due to non-viable or pleiotropic mutant phenotypes, complex organ structure, and difficulties with extraction and detection of GIPCs. I propose reverse-genetic characterization of GIPC biosynthesis in Physcomitrella, where expansion of gene families and simple morphology will facilitate mutant analysis. Further, I will use Physcomitrella to dissect the connection between sphingolipid metabolism and PCD, which is well-recognized, but mechanistically obscure. I will perform a mutant screen with Physcomitrella protoplasts for resistance to the ceramide synthase inhibitor and PCD trigger Fumonisin B1. The causal mutations will be identified by next-generation ma
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Targeted Protein Degradation as a New Experimental and Therapeutic Approach for Pancreatic Ductal Adenocarcinoma' (PROTAC-PDAC).

assistant: **Innovation**

Pancreatic ductal adenocarcinoma (PDAC) is a life-threatening disease with few treatment options. Recently, the chemical space for targeted therapeutics was significantly increased by the development of compounds that induce protein degradation (PROTACs), but so far, they are unavailable for PDAC. The main motivation of PROTAC-PDAC is to develop novel targeted therapies for PDAC. The project is based on our accomplishments in three crucial areas. First, my group identified – as target candidates – a series of transcription factors that are absolutely required for PDAC growth in vivo. Second, we developed dozens of potent, specific PROTACs, thereby gaining deep insight into the underlying design principles and synthesis procedures. Third, we established genetic models in mice for simulating PROTAC function and discovering ideal target–E3 ligase pairs. In PROTAC-PDAC, we will develop compounds that degrade key oncogenic transcription factors and inhibit pancreatic tumor growth with minimal toxicity in healthy tissues. We will start by implementing the Auxin degron system in a murine PDAC model, to induce degradation of the target candidates and select four priority targets with the highest therapeutic index (Aim I). Then, we will assess their oncogenic functions by analyzing molecular, cellular and organismic consequences of acute depletion in mice (Aim II). In parallel, we will develop pharmaceutical PROTACs to induce target degradation and analyze their efficacy in PDAC models (Aim III). Finally, with the aim of developing less toxic PDAC therapy, we will identify pancreatic E3 ligases for the design of the first tissue-specific PROTACs that induce target degradation primarily in pancreatic tumor cells (Aim IV).While the main goal of PROTAC-PDAC is to develop new PROTAC