RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'European Action for Social Entrepreneurship Support', explaining its relevance to EU policy priorities under Horizon Europe.

assistant: **Impact**

Through events, summits, gathering of existing tools for best practice and a digital ecosystem for social entrepreneurs, we will strengthen the ecosystem for social innovation in Europe. We will create a European peer-to-peer academy for social & impact entrepreneurship support. Co-owned by European support organizations, we will endeavor to increase the capacities of social entrepreneurship support organizations in Europe. The academy aims to sustainably boost the impact of the European ecosystem for social & impact-driven entrepreneurship.We will gather and promote tools and facilitate locally based events, and facilitate summits where knowledge, methods, best practices, and tools are disseminated. In addition, we will build on existing digital platforms to create a social innovation ecosystem where best practices, knowledge and tools will be granted free of charge for social entrepreneurs.Key output from the project:-Registration of best practice out before and after intervention. The registration forms from the first registration will be used to select relevant tools to be included in the digital ecosystem. -Two social innovation policy summits and a final conference for actors in the social innovation ecosystem.  -Collection of tools from actors working with social innovation. The tools may come from relevant accelerators, investors, incubators and public entities such as universities and government. All activities and tools will be free accessible at the digital ecosystem. The digital ecosystem will be built on existing software systems.The digital ecosystem will be a strong European network with various actors within different branches and knowledge from professionals within the field.


**Keywords:** Intervention, registration, eco-innovation
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'European Biofuels Technology Platform Secretariat' (BIOFUELSTP), addressing dissemination and exploitation.

assistant: **Impact**

The Biofuels TP was officially launched in June 2006. Since October 2006, a secretariat, partly funded by the EC, has supported all TP activities. A key achievement of the TP was the publication of the Strategic Research Agenda (SRA) and the Strategy Deployment Document (SDD) in January 2008. Currently the Biofuels TP focuses on implementing the SRA/SDD and on contributing to the European Industrial Initiative on Bioenergy in the frame of the European Strategic Energy Technology Plan (SET-Plan). The contract of the current secretariat will end in March 2009. The overall objective of this proposal for a continuation of the Secretariat is to proactively support the Biofuels TP with a view to its changing needs. The Secretariat will be responsible for all organisational, administrative and communication tasks. Organisation, preparation and follow-up of Steering Committee Meetings and Working Group Meetings (WP2) as well as the organisation of events such as Stakeholder Plenary Meetings and workshops (WP3) form an important part of the day-to-day work. Additional priority work areas will include the Secretariat actively supporting the TP via increased networking activities. These aim at identifying and creating synergies with other ongoing biofuels related R&D activities and will involve TPs, ERA-Nets and national as well as EU policy makers (WP-3). Furthermore, the Secretariat will develop “Research Priority Documents” to facilitate the implementation of the SRA (WP4). The new Secretariat will monitor biofuels related R&D developments, maintain databases and draft documents such as position and strategy papers for the Biofuels TP (WP5). Compared to the ongoing activities which mainly focus on organisational, administrative and communicative support, this proactive approach
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Federated virtual twins for privacy-preserving personalised outcome prediction of type 2 diabetes treatment' (2021-2027) targeting Horizon Europe.

assistant: **Abstract**

Virtual twins may be used as prognostic tools in precision medicine for personalised disease management. However, their training is a data hungry endeavour requiring big data to be integrated across diverse sources, which in turn is hampered by privacy legislation such as the General Data Protection Regulation. Privacy-enhancing computational techniques, like federated learning, have recently emerged and hold the promise of enabling the effective use of big data while safeguarding sensitive patient information. In dAIbetes, we build on this technology to develop a federated health data platform for clinical application of the first internationally trained federated virtual twin models. Our primary medical objective is personalised prediction of treatment outcomes in type 2 diabetes, which afflicts 1 in 10 adults worldwide and causes annual expenditures of ca. 893 billion EUR. While healthcare providers are becoming increasingly effective at targeting diabetes risk factors (e.g. diet or exercises), no guidelines as to the expected outcome for a given treatment for a specific patient exist. To address this urgent, yet unmet need, the federated dAIbetes technology will harmonise existing data of ca. 800,000 type 2 diabetes patients of 4 cohorts distributed across the globe, and learn prognostic virtual twin models. Those will be validated for their clinical relevance and applied in clinical practice through a dedicated software. We aim to demonstrate that our personalised predictions have a prediction error that is at least 10% lower than that of population average-based models. This federated virtual twin technology will enable personalised disease management and act as a blueprint for other complex diseases. Our consortium combines expertise in artificial intelligence, s
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Advanced Spectral Techniques in Econometric Modelling of Macro-Financial Linkages in the Euro area' (ASpecT).

assistant: **Innovation**

Business cycles (BCs) have always attracted considerable attention by policymakers, practitioners & politicians for monitoring current economic conditions & predicting future trends. Recent works present mixed evidence about BC co-movement in the EU & globally depending on the period, data frequency & methodology employed. A flurry of interest in econometric modelling based on spectral methods is observed mostly during the last decade. Until recently multiscale spectral analysis (MSA) represented an important research area only in engineering & natural sciences, wherein the utilization of timescales in the analysis of different modes of behavior isvery common. The use of MSA in economic sciences is in its infancy and many properties are still unexplored. In economics the focus is attributed to long-run equilibrium relationships derived after disaggregating at different time horizons. Via MSA, the low-frequency component of BCs that captures the true dynamics is identified & the high-frequency fluctuations that distort the economic systems are extracted.In this multidisciplinary project advanced spectral techniques that allow for simultaneous analysis in the time & frequency domain are utilized to detect the latent complex dynamics of global markets & particularly of the Eurozone. The study intends to quantify domestic/international interdependencies & analyze BC synchronicity & convergence in the Euro area. Moreover, it investigates macroeconomic & financial causal linkages, reveals new market stylized facts & develops new forecasting models. Integration proceeded in the Eurozone due to the introduction of Euro, until the financial crisis of 2007-2010. The EU debt crisis serves as a catalyst towards therevision of institutional regulations for monetary & fiscal consolid
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Ecosystems Mapping and Planning through Open dialogue for Wider cooperation across EU Regions based on the Entrepreneurial Discovery' (EMPOWEREDbyNEIA) under Horizon Europe.

assistant: **Objectives**

EMPOWERED by NEIA brings together a team of stakeholders from 7 EU countries (2 Regional Innovation/Development Agencies and 5 Business Support Organizations - incubators and accelerators) with he ambition to engage in a process of peer mutual learning and cooperation and support Clean Tech for Sustainable Development. Based on an in-depth analysis of strengths, weaknesses, challenges and gaps in the ecosystems they represent, the EMPOWERED by NEIA team members strive to bring together the members of the innovation ecosystems they represent as active stakeholders in bottom-up policy-making activities tailored to their needs. Through an Entrepreneurial Discovery process, we aim to stimulate a participative process that will allow to identify the best innovation opportunities in each ecosystem and align them with the ones of the peers. The results of the Entrepreneurial Discovery run locally by each partner will represent the foundation of Action Plans, elaborated according to the European Entrepreneurial Region approach, to strengthen the collaboration between the Regional European Innovation Ecosystems. These plans will be back up with collaboration and project ideas for which public and private funding will be sought. Through the involvement of the EMPOWERED by NEIA consortium partners in landmark initiatives such as the European Association of Development Agencies (EURADA), the Vanguard Initiative or the activities of the European Entrepreneurial Region initiative, we will connect with external peers to expand the learning and cooperation process, disseminate our activities and increase their impacts.


**Keywords:** Sustainable Deep tech; mutual learning; parctices exchange; Regional Action Plans; Entrepreneurship; policy making
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Ultra Frequency-Stable Laser via Spectral Hole Burning in Rare-earth Ion Doped Crystals' (UltraStabLaserViaSHB).

assistant: **Concept**

The UltraStabLaserViaSHB project seeks to catch the currently elusive grand prize of time and frequency metrology: a frequency source with a relative stability on the order of 10^-18 at 1 s. The desirability of this goal is borne of the near-future redefinition of the SI unit of time, the second. As optical atomic clocks surpass microwave-frequency atomic clocks in accuracy, the switch to an optical definition of the second drives the metrology field to strive to the fundamental performance limit of optical clocks, the quantum projection noise limit. Currently, optical clock performance is limited by frequency fluctuations of the optical-cavity-stabilized laser field which probes the atoms' optical transition. The optical lattice clocks located at SYRTE could reach their quantum projection limit if a probe laser with a sufficient frequency stability could be realized.The project proposed here seeks develop an ultra frequency stable laser at SYRTE to reach this performance via a paradigm shift in laser stabilization, away from optical cavity frequency references (which themselves approach their fundamental limit, Brownian noise) and toward a novel method: laser stabilization via spectroscopy of rare-earth ion doped crystals. This is achieved through a technique called Spectral Hole Burning (SHB) where a spectral pattern is imprinted on the crystal at cryogenic temperatures by a pre-stabilized laser (a spectral ""hole"" is ""burnt""). A probe beam then interacts with this spectral hole and the resulting de-phasing of the probe beam provides the source for a control signal which allows us to actuate the probe laser, stabilizing it to the narrow line of the rare earth ion. Early results in this young technique are extremely promising and its limits are yet undiscovered. The
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Development of novel tools and techniques for the study of the structure and dynamics of GABAergic inhibitory synapses' (GABAAR).

assistant: **Concept**

Studies have shown that the number of gamma-aminobutyric acid receptors (GABAARs) present at the plasma membrane controls GABAergic transmission. In fact, a number of neurological and neuropsychiatric disorders have been associated with deficits in the expression and activity of GABAARs. Although of great importance, the exact mechanism by which these receptors accumulate on the neuronal plasma membrane, enabling them to mediate inhibitory neurotransmission, has not been elucidated. By implementing established tools and through the development of novel techniques, work proposed aims to investigate the processes that underlie the assembly and maintenance of GABAergic synapses as well as their modulation under physiological and diseased states. Through the use of super-resolution imaging techniques such as photoactivated localization microscopy (PALM) and stochastic optical reconstruction microscopy (STORM), we aim to study the number and distribution of GABAARs at synapses and to provide a structural picture of the scaffolding protein gephyrin. To aid in the elucidation of the role of gephyrin in the stabilization of GABAARs at synaptic sites, we propose the use of dual-color super-resolution imaging to study the interaction between these proteins. For more accurate and detailed three-dimensional structural studies, we will couple super-resolution microscopy with astigmatic imaging. Importantly, our objectives also encompass the development of novel tools that, once established, can be applied to the study of inhibitory synapses as well as many other biological systems. These techniques involve the incorporation of unnatural amino acids that can later be tagged with organic fluorophores via click chemistry. Because of the presence of a single fluorophore per receptor, si
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'the role of Stress History on the EARthquake potential of faults' demonstrating excellence, impact and implementation quality for a Horizon Europe call.

assistant: **Abstract**

The extent to which earthquake phenomena can be accurately assessed ultimately depends on how well the underlying physical processes are understood. Earthquake physics is primarily controlled by fault frictional properties and fluid pressure, which have been widely tested in laboratory rock deformation experiments. During the last 50 years, these experiments have provided fundamental contributions to our understanding of earthquake physics. However, in most experiments, the fault is loaded toward earthquake-slip under constant effective normal stress or via an increase in effective normal stress, i.e., load-strengthening. Nonetheless, numerous natural faults are affected by a reduction in effective normal stress during tectonic loading, i.e., load-weakening, and this condition is dominant in induced earthquakes due to fluid-injections in modern energy production. Further, along mature fault zones characterized by a thick damage zone and fault core, load-weakening likely promotes fault dilation, instead of compaction, with strong implications for fault hydro-mechanical behaviour. With SHEAR, I propose to fill this knowledge gap via laboratory experiments designed specifically to investigate the influence of loading path, and in particular the load-weakening path in fault physics, taking advantage of a world-class deformation apparatus. Laboratory results will be integrated with acoustic techniques to shed light on the physical processes at play and inform microphysical models that, coupled with field studies, will allow for the upscaling of experiments and provide a broader comprehensive picture of tectonic faulting. For the SHEAR action, the experience I acquired during my Post-Doc at EPFL (Switzerland) will be fundamental. The vibrant research environment in Sapienza w
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Structuring Quantum Light for Microscopy'.

assistant: **Innovation**

Optical microscopy, perhaps the most important tool in biomedical investigation and medical diagnosis, provides structural and functional information about biological specimen in a non-invasive and non-ionizing way. However, this technique still faces the challenge of imaging small and weakly scattering objects (e.g.a single cell) embedded inside complex biological tissues causing optical aberrations and scattering. This problem is even more critical in the case of samples that cannot be labelled or do not spontaneously emit light. In SQiMic, I will go one major conceptual step beyond the current paradigm by merging the fields of quantum imaging and light structuring to build a new quantum 'toolbox' for microscopy. My novel approach is based on my pioneering work showing that wavefront shaping techniques, initially developed for laser light manipulation, can also shape higher orders of optical coherence, allowing deterministic tailoring of quantum properties of light such as entanglement. I will use this approach to leverage some genuine quantum imaging concepts such as quantum holography, quantum interferences and quantum illumination, to break the current limits of fluorescent-free classical microscopy and image complex objects with higher resolution, better contrast, reduced aberrations, and less noise. Ultimately, I aim to deliver a quantum-enhanced microscope with unprecedented performances that can be used as a practical tool for biological imaging without labelling the specimens or relying on their possible ability to emit light.From a methodological standpoint, SQiMic will bridge knowledge from quantum imaging, light structuring, adaptive optics, wavefront shaping, sensors technologies and computational imaging. It will deliver a whole new class of optical imagi
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Multifunctional bioresorbable biocompatible coatings with biofilm inhibition and optimal implant fixation' under Sixth Framework.

assistant: **Concept**

Most common reasons for revision surgery of implants are loosening (65%), dislocation (9%) and infection (7%). The revision rate of hip replacement surgery is between 10-20%. Rates of implant loss for dental implants is 15% over a 5-year period. Biofilm formation is the major pathogenic factor.The project, driven by 7 dedicated complementary Hi-Tech SMEs, aims at gaining the scientific and processing knowledge to assist the SMEs in the development of the next generation multi-functional coatings for or thopaedic and dental implants and fixation devices for adequate implant fixation, bioresorbability, bioactivity, biocompatibility as well as biofilm formation inhibiting functionality, that should drastically reduce the currently experienced need for implant revisions due to loosening and infections.The envisaged radical innovations and major breakthroughs are:- development of new substrates and coatings with enhanced biocompatibility,- development of radically new or improvement of existing coating techniques for processing bioresorbable and biocompatible coatings with a graded interface and tailored porosity,- in-depth understanding of implant substrate/coating/bone interfacial structure, design and engineering of optimal implant fixation,- knowledge on biofilm formation and inhibition,- formulation and evaluation of biofilm inhibitors incorporated into the coating.The project addresses the integration of nanotechnologies, materials science and advanced technologies to improve health and quality of life of European citizens and creating wealth through novel knowledge-based and sustainable products (biomaterials) and processes (coatings), by means of fostering breakthrough applications through the integration of multi-disciplinary research developments.The project will c