RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Neuromodulatory effects of controlled breathing (CB) interventions on executive functions (EF) and mental well-being in burnout disorder' (CB).

assistant: **Innovation**

The goal of the research project is to investigate the neuromodulatory effects of controlled breathing (CB) interventions on enhancing cognition (i.e., executive functions (EF)) and mental well-being in individuals suffering from burnout disorder. Burnout disorder, signified by debilitating psychological, cognitive, and physiological symptoms, is a growing concern in contemporary society. With an estimated average prevalence of around 20% in the general population and significantly higher rates in specific professional groups (e.g., up to 80% in healthcare workers), burnout disorder necessitates innovative intervention and treatment approaches.The current multidisciplinary study intersects cognitive neuroscience, psychology, biomedical engineering, and health sciences to explore how CB can modulate brain oscillations and improve cognitive and mental health outcomes in burnout disorder.The project will employ a randomised controlled trial (RCT) to examine CB’s impact on three key layers: (1) brain oscillations (i.e., electroencephalography (EEG) measurements), (2) cognition (i.e., standardised EF tasks), and (3) mental well-being (i.e., standardised scales). By utilising EEG, standardised EF tasks, and standardised mental well-being symptom scales, the study will assess pre- and post-intervention changes in neural activity, cognitive performance, and mental well-being.The research findings will be grounded in a theoretical framework – the Free Energy Principle – allowing the formulation of further testable and falsifiable hypotheses and leading towards a structured methodology for investigating the specific mechanisms through which CB influences neurophysiological, cognitive, and psychological processes in burnout, and ensuring that the findings are robust and reproducib
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Fifth Framework proposal on 'Accelerated carbon dioxide deliming'.

assistant: **Concept**

The problems of using the generally accepted Best Available Technique" of carbon dioxide as a declaiming agent includes the inability to deli me full substance hide in comparable time-scale to that of traditional declaiming agents (ammonium salts). However, traditional carbon dioxide declaiming offers the advantage of being more environmentally friendly , having a considerably lower impact on tannery effluents. The objectives of this project will be to investigate methods for increasing the concentration of the declaiming agent carbon dioxide in the declaiming float such that full substance hide can be effectively deli med. Several alternatives will be investigated whereby either the carbon dioxide will be dissolved in water at elevated pressure before being directed into the non-pressurised declaiming vessels or the carbon dioxide will be directed into a sealed pressurised declaiming vessel. The effects of these treatments on the rate of declaiming, physical, mechanical and organoleptic properties of the leather will be investigated. Furthermore, preliminary screening of suitable bating enzymes for the pH obtained with carbon dioxide declaiming will be carried out."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Geophysical Exploration using Advanced GAlerkin Methods' under Horizon 2020.

assistant: **Concept**

The main objective of this Marie Curie RISE action is to improve and exchange interdisciplinary knowledge on applied mathematics, high performance computing, and geophysics to be able to better simulate and understand the materials composing the Earth's subsurface. This is essential for a variety of applications such as CO2 storage, hydrocarbon extraction, mining, and geothermal energy production, among others. All these problems have in common the need to obtain an accurate characterization of the Earth's subsurface, and to achieve this goal, several complementary areas will be studied, including the mathematical foundations of various high-order Galerkin multiphysics simulation methods, the efficient computer implementation of these methods in large parallel machines and GPUs, and some crucial geophysical aspects such as the design of measurement acquisition systems in different scenarios. Results will be widely disseminated through publications, workshops, post-graduate courses to train new researchers, a dedicated webpage, and visits to companies working in the area. In that way, we will perform an important role in technology transfer between the most advanced numerical methods and mathematics of the moment and the area of applied geophysics.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Siberia, Information Technologies and Europe' in the context of a Sixth Framework call.

assistant: **Objectives**

The objective of SITE is to increase cooperation between Russian and EU researchers in the area of the IST Priority. The project will focus on the Sibirsky region of Russia, and achieve its objectives by:   1. Establishing and training a multilevel support network of Regional Centres and European Offices in Russian organisations with substantial research expertise in IST. The support network will promote the IST Priority to research teams and help them understand its objectives and procedures;  2. Supporting partnering between EU and Russian researchers by developing a partnering mechanism and organising real and virtual brokerage events;  3. Providing help to EU and Russian researchers who are developing joint proposals with advice and support, through a knowledge base, e-training for proposers, and proposal review. The measurable results which will be achieved through the project are:  1. Eight regional centres and 56 European Offices within Russian organisations with substantial research expertise in IST will be trained so that they can explain how Russian research teams can participate in the IST Priority;  2. A partnering database of profiles of 320 Russian research teams will be developed. The profiles will describe the organisation, its research interests and any ideas for collaborative projects and the types of partners required;  3. The partnering activity will help establish 20 continuing relationships between research teams in the EU and Russia. A much larger number of EU researchers will become aware of the potential to collaborate with teams in the Sibirsky region;  4. Ten joint EU-Russian teams will be assisted in proposal preparation.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Acquisition of Mathematical Concepts in the Human Brain' in the context of a Horizon 2020 call.

assistant: **Objectives**

How do humans learn and manipulate mathematical concepts? In previous research, I have shown that (1) advanced mathematical reflection on concepts encoded for many years does not recruit the brain circuits for language; (2) non-verbal acquisition of geometrical rules call upon a language of thought that is independent of natural spoken language. However, the question remains to understand whether advanced mathematical acquisition in schools, where knowledge is taught verbally, also dispenses with the human ability for language. Building on the expertise I have acquired in functional MRI testing of math experts, with the help of my supervisors, the present project proposes to track the evolution of children and adults' brain activity during learning. To this end, we will expose participants to typical classroom lessons with math-related content. Using fMRI, coupled with traditional general linear model and original inter-subject correlation analyses, we particularly aim to investigate whether (1) similar learning neural mechanisms are at work in adulthood and childhood; (2) language plays a role in mathematical acquisition; (3) understanding dropout correlates with a specific neural marker. A first experiment will aim to identify brain activation that changes with learning of math versus general semantic concepts in adults. It will be conducted in Italy, under the supervision of Pr. Piazza who is a leading expert in the field of math cognition, and mainly uses fMRI to study the plastic changes occurring in the brain during learning in particular of symbols (words, numbers, and math symbols). A second experiment will probe whether the neural patterns observed during adult learning of math laws also apply to children's learning of math laws such as commutativity. It will b
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fourth Framework proposal on 'Drug hepatotoxicity: an integrated clinical and mechanistic investigation'.

assistant: **Innovation**

The general aim is to detect, understand, predict and avoid drug hepatotoxicity: Clinical studies will be undertaken to elucidate clinical, environmental and pharmacogenetic risk factors and to determine whether modulation of drug bioactivation/detoxication in patients in vivo influences their susceptibility Mechanistic investigations will be used to investigate pathways of drug bioactivation and toxicity, and to define cellular and immunoallergic mechanisms of drug toxicity.Drug hepatotoxicity is a major clinical and socio-economic problem in the E.C. This is because hepatotoxicity is among the most frequent of the organ toxicities caused by drugs and because drug-induced hepatotoxicity may lead to chronic disease, death or liver transplantation. Although hundreds of hepatotoxic drugs have now been identified, in only a few cases have the mechanisms of toxicity been defined. In consequence, little is known concerning the reasons why some patients are susceptible to the hepatotoxicities, but many other patients are not. Furthermore, model systems which can be used to predict and study the toxicities are not available. In view of this, a multidisciplinary and multinational European research network (EUROHEPATOX) will be established and a strategy will be adopted which will make possible integrated clinical, molecular and cellular studies of mechanisms of drug hepatotoxicity. Clinical studies: Detection of patients with drug hepatotoxicity via prospective/retrospective trials Investigation of clinical, environmental and pharmacogenetic risk factors effects of modulating bioactivation/bioinactivation on patients' susceptibility Drug bioactivation and bioinactivation Identification of metabolic and genetic risk factors and chemoprotective factors Development and validation
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Multiphysics modelling and neural networks synergy to enhance the outcome of robotic catheter ablation for the treatment of atrial fibrillation' (PhyNeTouch), addressing dissemination and exploitation.

assistant: **Impact**

Atrial fibrillation is the most common cardiac arrhythmia affecting more than 7.6 million people in Europe, while future projections estimate a worldwide increase by over 60%. Catheter ablation has evolved over the last decades to an important therapeutic modality for patients with atrial fibrillation. Despite the fact that modern robotic ablation systems made precise catheter navigation possible, the success rate remains limited and the risk for complications is significant. As a result, atrial fibrillation remains a serious health issue, influencing the quality of life, and the source of very important socioeconomic problems.The vision of PhyNeTouch project (reads: fine-touch) is to capitalize on the recent advancements in computational modelling and artificial intelligence in order to enhance the safety of robotic catheter ablation procedure and improve its success rate. Novel multiphysics modelling techniques based on meshfree methods will be combined for the first time with physics-informed neural networks to advance the state-of-the-art and produce accurate bioheat distribution maps in real-time which currently are not available in the clinical setting.Predicting bioheat distribution in the tissue during the operation will assist the decision making and will allow improving the outcome of robotic catheter ablation. In this way, PhyNeTouch aims to contribute to the healthy ageing of citizens of EU and the rest of the world, as well as to reduce the socioeconomic burden, by reducing the complexity of this procedure and making it accessible to a wider public.


**Keywords:** catheter ablation, heart, robotics, biomechanics, meshfree methods, artificial intelligence, neural networks, bioheat transferring prediction
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'REliable Advanced Diagnostics and Control Tools for increased lifetime of solid oxide cell Technology', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Solid Oxide Electrolysis (SOE) and its possibility to operate in reversible mode (rSOC) can play a major role in H2 production at low cost and for renewable energies storage. These operating modes with high current and transients can induce degradation that needs to be mitigated for successful system deployment.  Federating the cumulated advances built up in preceding collaborative projects, REACTT, with an established expert team, will realize a Monitoring, Diagnostic, Prognostic and Control Tool (MDPC) for SOE and rSOC stacks and systems. Its hardware platform will embed diagnostics and prognostics algorithms, and interact with the system power converters without modification. It contains (a) an innovative excitation module to probe the stack with PRBS (pseudo-random binary signal) or sine stimuli, and (b) a control coordination unit, interfaced with real-time optimisation (RTO). The latter uses on-line measurements with a constraint-adaptive algorithm that drives the system to optimal operation, respecting all safety boundaries. Together, this approach will achieve to supervise and analyse the (reversible) electrolyser system, increase its reliability and extend its stack lifetime.  REACTT will demonstrate the effectiveness of this approach by tests on a SOLIDpower (SP) 5 kWe SOE system and on an rSOC x kWe CEA system, both at TRL6. This validation in two different operating modes with two different stack designs will prove the generic character of the developed tools, which can then be extended towards multiple technologies and higher power applications. It will reduce the operation and maintenance costs by 10%; the additional cost of the MDPC tool will not exceed 3% of the overall system manufacturing costs.   These ambitious targets will be pursued in close collab
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'CULTURAL AND CREATIVES INDUSTRIES AS INNOVATIVE DRIVERS TO IMPROVE URBAN QUALITY OF LIFE' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

The Spanish Presidency of the Council of the European Union will held during the second semester of 2023 a European Conference entitled ‘Cultural and creative industries, cities and citizens fostering sustainable development and the European way of living’. The objective is to reflect how the Cultural and Creatives Industries (CCIs) collaborate and contribute to improve people's quality of life by creating solutions through Culture and Science,The event will pretend to be an international meeting point between Culture and Science by displaying, in a demonstrative, interactive and participatory way, CCIs’ European and collaborative projects and initiatives that are not only innovative and sustainable, but also accessible, affordable, socially committed and enriching for all in line with the New European Bauhaus (NEB) initiative. In this way, the event will be able to reflect how cultural and creative industries can collaborate as social and innovative drivers through a collaborative network.The Conference will be organized held on 11, 12 and 13 July 2023 in Barcelona by the Spanish Foundation for Science and Technology (FECYT), in partnership with the Spanish Ministry of Science and Innovation and the Spanish Ministry of Culture and Sports.


**Keywords:** Spanish Presidency, Culture, Science, Conference, Cultural and Creatives Industries
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Fourth Framework proposal for the project 'Am improved end-effector for one-atmosphere diving suits'.

assistant: **Objectives**

This Project will provide an Improved End-Effector (IEE) to replace the simple pincers at present used on one atmosphere diving suits (ADS). By enabling the operator to carry out simple manipulations and operate power hand tools, this will greatly improve the productivity of the ADS, making the latter a realistic and versatile alternative to saturation divers. The IEE will be controlled by the operator's hand in a glove within the ADC and operated by electro-rheological actuators hydraulically linked to the IEE.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'High-throughput 4D imaging for nanoscale cellular studies'.

assistant: **Objectives**

Fluorescence microscopy is an invaluable tool for exploring the structure and function of biological processes. It provides high specificity and contrast for the observation of cellular components tagged with fluorescent molecules in a minimally invasive fashion, allowing the study of live specimens. Furthermore, the development of super resolution (SR) fluorescence microscopy has unlocked the access to spatial resolutions beyond the diffraction limit of visible light (~250nm), fuelling the discovery of new biological structures and dynamics. Nevertheless, achieving resolutions below ~10nm is challenged by multiple trade-offs between spatial and temporal resolutions, depth of observation and photo toxicity, making it difficult or impossible to obtain a molecular resolution. Additionally, axial resolutions are inevitably poorer than lateral ones, unless utilizing a complex multi-objective lens approach.I recently developed MINFLUX, a localization technique that merges concepts of SR with information theory. It achieves isotropic nanometer resolution in three dimensions with a single objective lens and has unrivaled spatio temporal resolution. However, a platform that enables these capabilities in a high-throughput manner for entire cells and tissue has not yet been developed. I aim to fill this technological gap; with my background and experience, I am in a unique position to assure the success of this project and establish these technologies in the scientific community. The performance of fluorescence imaging and tracking will progress orders of magnitude in the years to come, signaling yet another revolution for optical nanoscopy.


**Keywords:** super resolution microscopy, single molecule tracking, high-throughput parallelization
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Functional analysis of arabidopsis thaliana rop1, a model nanomachine' will create measurable scientific, societal and economic impact aligned with Fifth Framework.

assistant: **Impact**

The work proposed here aims to study a Rap gene from Arabidopsis using genetic, molecular and biochemical techniques. The work will contribute to deciphering plant signaling networks controlled by AtRop1 . identify physical interactions in vitro and in vivo, and unravel important functional aspects of this molecular switch in Arabidopsis cells.