RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'The evolutionary implications of genetic conflict' to be submitted under Seventh Framework.

assistant: **Abstract**

The study of genetic conflict is developing at an almost explosive rate. The recognition that genes or alleles residing in individuals of the two sexes may have conflicting interests is transforming evolutionary biology and, likewise, conflict between genes showing different modes of transmission may fundamentally affect adaptive evolution. The research proposed here will push the frontiers of genetic conflict research and establish new domains. It is aimed at exploring the novel possibility that conflict between mitochondrial and nuclear genes have far-reaching implications for adaptive evolution and at advancing our understanding of the biological consequences of sexual conflict. The project consists of several interrelated parts and will employ insects as model systems. First, I will assess to what extent genetic variation in fitness is sexually antagonistic and what life history traits contribute to sexually antagonistic variation. Second, I will elucidate the genomics of metabolic rate and measure selection on metabolic phenotypes. Third, I will test whether sexually antagonistic epistatic interactions between mitochondrial and nuclear genes generate conflict over metabolic rate. Fourth, I will test the hypothesis that sexual conflict contribute to the evolution of primary and secondary sexual traits. Fifth, I will shed light on the complicated evolutionary interplay between sexual conflict and mating system evolution. I will employ an innovative research strategy, ‘experimental genomics’, in which genomic data is used to guide experimental evolutionary work with distinct genotypes. The research outlined here will collectively provide an unprecedented wealth of information into the role of genetic conflict in several horizons of adaptive evolution, ranging from DNA
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Facilitating and Enhancing Access to Life-long Learning SOlutions for a Wide variety of Social categories' under Fifth Framework.

assistant: **Concept**

FELLOWS objective is to develop and validate new distant learning services addressing the needs of populations with low education level and not involved in formal education and training environments. FELLOWS will develop an Open Distant Learning platform adapted to the needs of the targeted groups, i.e. integrated in existing education and training practices, centred on the learning paradigm, user interfaces and supporting media (PC and set top box TV). The platform will be developed and validated in classed collaboration with trainers who will design courses, take over the training and remotely monitor the progress of the learners. For validation, FELLOWS will perform field trials with group of people threatened by exclusion or aside from the Knowledge Society currently under construction: immigrants, young marginal people, illiterate and women at home.Objectives:FELLOWS will develop and validate new distant learning services for user groups who need access to education and training outside formal education settings. Detailed objectives are:- Develop an ODL training service centred on the users (trainers and learners)- Reach people difficult to capture in formal education and training courses- Provide technical knowledge transfer to the trainers making sure they feel ownership of it- Develop consistent user interface optimised for the target groups reducing learning difficulties- Create an environment that facilitates European wide co-operation and sharing of resources by trainers and training institutes- Develop the required ODL infrastructure from Internet standards \(XML, JAVA, FLASH) to ensure the largest compatibility with and easy access from any terminal. Validation of the FELLOWS platform and approach will be done with illiterate people, women at home and young
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'PJ22:Validation and Demonstration Engineering' in the context of a Horizon 2020 call.

assistant: **Objectives**

The aim of SESAR2020.PJ22 is to address one of the Transversal Activities, specifically Validation & Demonstration Engineering. In SESAR 1, the application of an engineering methodology defining the process for development of verification and validation platforms, was optionally mandated to the primary projects, leading to a different level of information available across the Programme. The delivery of information to SJU did not always reach the necessary consistency and quality, e.g. preventing the understanding of coverage and traceability of operational requirements vs. technical requirements. SE data were typically captured via Word templates requiring significant effort to extract the information with not homogeneous level of details thus insufficient to guarantee the usability and significance for the SESAR Community. In SESAR 2020 there is a demand to improve consistently the situation and PJ22 will provide a System Engineering Data Management Framework (SE-DMF), aiming to support all SESAR Solutions with a (web based) platform for Requirements Management to capture data in a structured way ensuring consistency, coherence and coverage at Programme level. PJ22 will develop an efficient approach based on a data-centric, data-driven rather than document-based paradigm.  SE-DMF will be set up as a service and run in a secured IaaS infrastructure to enable cost reduction, high level of ROI, ease of use and scalability. The project will support the SESAR Solution Maturity Lifecycle and Gates.Another challenge is to identify a set of strategic validation tools and interoperability solutions to improve the SESAR 2020 validation process. Maintaining and improving the development methodologies for the SESAR solution and VLSD projects together with managing the catalogue of
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Assessing the impact of climate fluctuations on hibernation phenology using novel dental biomarkers' in the context of a Horizon Europe call.

assistant: **Objectives**

Many heterothermic mammals exploit multi-day torpor (i.e. hibernation) to face harsh climates. The timings and the regulations of this process are controlled and influenced by several intrinsic and extrinsic factors such as e.g. the circannual biological clock of the animal, the day-length, the spring temperature, the snow-melt date. Yet, how these animals answer(ed) global climate changes is still a matter of debate. With the AROUSE project I will examine the hibernation timing and the bone elemental metabolism of small mammals from a new unexplored perspective, by analyzing well-dated fossil and modern hibernating rodent teeth straddling the last glacial-interglacial cycle. Specifically, I will exploit the enamel incisor micro-chemistry (high-spatially resolved elements and isotopes), histomorphometry and proteomics of geographically-constrained Alpine marmots to: 1) precisely measure sex-specific hibernation length; 2) investigate metabolic changes in relation to (paleo)climate seasonal fluctuations; 3) unravel dental enamel secretion and mineralization behavior during winter torpor; 4) search for specific dental chemical biomarkers of hibernation, transferable to other disciplines. For the first time, this project will provide a robust tool for the retrospective study of hibernation events in dental specimens, allowing to deepen our knowledge about hibernation plasticity but also to possibly investigate the evolutionary trajectories of torpor in deep-time. AROUSE will also help to understand how marmots adapted to secular climate variations, possibly forecasting the effects of global warming on modern hibernating mammals.


**Keywords:** hibernation,  marmot,  tooth,  dental histology,  enamel,  elemental composition,  isotopes,  phenology
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Stop transmission of gambiense human African trypanosomiasis' (STROGHAT).

assistant: **Innovation**

Gambiense human African trypanosomiasis (gHAT) is a neglected tropical disease caused by trypanosome parasites. gHAT is fatal if left untreated. So far, treatment options for gHAT were limited and toxic, forcing control programs to avoid overtreatment through complex diagnostic procedures, including screening with a serological test, laborious microscopic confirmation of seropositives and lumbar puncture for disease stage determination. This resulted in loss of up to 50% of gHAT cases, which remained untreated. Recently a non-toxic single dose oral drug, acoziborole, has shown 98.1% efficacy in a phase III trial, irrespective of gHAT disease stage. Acoziborole removes the need for lumbar puncture and appears safe enough to treat serological suspects without microscopic confirmation (Screen & treat). The STROGHAT project 1° will evaluate effectiveness of a Screen & treat approach to rapidly reduce gHAT prevalence in an entire focus; 2° will extend acoziborole safety documentation; 3° and will analyze costs of this new approach. To achieve these objectives, Screen & treat will be implemented, actively and passively, for 3 consecutive years in the gHAT focus of Nord Equateur in D.R. Congo. Available geographical information will be exploited to specifically target villages where gHAT was recently, or still is present. Detection at a reference laboratory, of the trypanosomes nucleic acids in blood collected before treatment, will retrospectively identify true gHAT cases among the treated serological suspects. After 3 years of intervention, the gHAT prevalence in the focus will be re-estimated. STROGHAT intends to provide the first evidence for recommending Screen & treat to national HAT control programs for elimination of gHAT. Through facilitated diagnosis, increased accep
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Seed health: development of seed treatment methods, evidence for seed transmission and assessment of seed health' (TESTA), addressing dissemination and exploitation.

assistant: **Impact**

Healthy seed are key to high crop yields, underpinning European and global food security. A wide range of diseases and pests are carried by seed and as well as spreading and increasing old problems, new problems may be introduced into the European Community countries via this route. There are currently opportunities to improve seed quality control by implementing emerging novel methodologies. The TESTA project will develop a range of novel methods to underpin the control of these diseases and pests, including faster, more accurate methods to assess the mode of seed transmission, economic and practical sampling approaches for the detection of low levels in large seed lots, novel and efficient generic detection methodologies, non-destructive testing methods and improved, effective and sustainable disinfection methods. Target crop and disease/pest combinations have been identified in consultation with EPPO, ISHI-ISF and ISTA. Outcomes from the project will include a comprehensive electronic database of seed transmitted diseases and pests, validated detection methods for target species, a validation protocol for assessing the efficacy of disinfection, as well as many key scientific publications. These will provide supporting methods and sources for the EU seed testing laboratories and plant health services.The consortium comprises experienced researchers who have been involved in key previous research projects funded by the EU and national authorities, representatives of EPPO, ISTA plant health panel and ISHI working groups as well as seed testing laboratories and SMEs involved in seed production. The consortium includes a member from South Africa who is an international expert on seed production in non-EU countries and will provide insight into emerging risks. Involvement
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Extending the outdoor navigation experience to the indoors' (2014-2020) under Horizon 2020.

assistant: **Objectives**

We also need location positioning indoors. The good news is that almost all of us have phones with a GNSS receiver. Indoor positioning does not only help us get from A to B in large buildings but positioning does not work indoors mainly due to low accuracy. Our patented unique GalNav InDoor technology allows us to use standard GPS receivers already present in mobile devices to continue tracking the user indoor. Other vendors have used pseudolites (“pseudo-satellite” transmitting GPS-like signals) but these remain extremely expensive and custom-built for specific facilities. At Galileo Satellite Navigation Ltd. (GSN), we are the first company to provide indoor GPS capability with “virtual holes in the roof” using patented microsimulators to enable satellite reception. This is a game changer for indoor positioning as it can render all other technologies obsolete and leverage the existing GPS infrastructure (such as Galileo in Europe).We will target large venues that have an interest in tracking people including office and industrial buildings, malls and department stores, trade shows, supermarkets and hospitals. We will follow a business model based on a software license (head unit management software and remote synchronization software) and hardware fee (head unit and remote unit).To reach our company goal of revolutionizing the GNSS market, we will bring outdoor positioning to the indoors with GalNav InDoor. Before we can launch GalNav InDoor to the market, we need to perform the Phase 1 Feasibility Study and then scale up the current GalNav InDoor TRL 6 prototype to a fully commercial system for with Phase 2 funding. The EU benefits include facilitated emergency response management, better location in transportation hubs, more accurate logistic and easier moving around
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Organic Semiconductors Interfaced with Biological Environments' (OSIRIS).

assistant: **Innovation**

Transducing information to and from biological environments is essential for bioresearch, neuroscience and healthcare. There has been recent focus on using organic semiconductors to interface the living world, since their structural similarity to bio-macromolecules strongly favours their biological integration. Either water-soluble conjugated polyelectrolytes are dissolved in the biological medium, or solid-state organic thin films are incorporated into bioelectronic devices. Proof-of-concept of versatile applications has been demonstrated – sensing, neural stimulation, transduction of brain activity, and photo-stimulation of cells. However, progress in the organic biosensing and bioelectronics field is limited by poor understanding of the underlying fundamental working principles. Given the complexity of the disordered, hybrid solid-liquid systems of interest, gaining mechanistic knowledge presents a considerable scientific challenge. The objective of OSIRIS is to overcome this challenge with a high-end spectroscopic approach, at present essentially missing from the field. We will address: 1) The nature of the interface at molecular and macroscopic level (assembly of polyelectrolytes with bio-molecules, interfacial properties of immersed organic thin films). 2) How the optoelectronics of organic semiconductors are affected upon exposure to aqueous environments containing electrolytes, biomolecules and cells. 3) How information is transduced across the interface (optical signals, thermal effects, charge transfer, electric fields, interplay of electronic/ionic transport). Via spectroscopy, we will target relevant optoelectronic processes with ultrafast time-resolution, structurally characterize the solid-liquid interface using non-linear sum-frequency generation, exploit
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'VELES Excellence Hub - Strengthening the South-East Europe Smart Health Regional Excellence and Boosting the Innovation Potential' in the context of a Horizon Europe call.

assistant: **Objectives**

Smart Health is EU Strategic Value Chain that contributes to growth, jobs and competitiveness. Health Data is the main enabler for the value chain, but it also depends on cutting edge technologies - AI, cloud computing, IoT, to integrate the dispersed knowledge and support innovative healthcare solutions and services. EC sets the creation of a European Health Data Space as a main priority, to promote better exchange and access to health data.On a regional level, the RIS3 strategies of the involved widening countries - Bulgaria, Romania, Greece and Cyprus emphasize the need for based on Big Data, AI and IoT digitalized healthcare, to enable personalized medicine, informed decisions, and improved disease prediction. RIS3 strategies also outline the need for more funding for R&I, policy coherence and development of territorially join innovation strategies.  A cross country coordinated approach is needed to align the separate endeavours towards an Excellent South-East Europe Smart Health Innovation Ecosystem enabled by a Regional Smart Health Data Space.VELES raises the level of innovation excellence in the South-East EU through creating a sustainable place-based innovation ecosystem, enabled by Regional Smart Health Data Space, including novel transformational framework, R&I and investment strategy and action plan for research, development and adoption of innovative and secure digital solutions that underpin the delivery of sustainable healthcare services. The Regional Smart Health Data Space will be demonstrated through the design of 4 interrelated pilots on Cancer treatment (Greece); Personalised/precision medicine of Alzheimer (Bulgaria); Cerebral tumours (Romania) and Dementia (Cyprus). The aim of VELES is to foster health data sharing regional and national strategies,
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Novel electroactive polymeric materials for dielectric elastomers actuators and soft robots' will create measurable scientific, societal and economic impact aligned with Horizon Europe.

assistant: **Impact**

Interfacing between humans and machine using the sense of touch through haptic devices, is becoming increasingly important for consumer electronics, robotics, medical and automotive applications. One bio-inspired way to achieve this is by developing soft haptic skins that can both part and receive information through touch.  However, developing soft haptic skins which have a significant tactile response and are robust enough for daily use in heavy use consumer applications is challenging.  Our approach uses novel self-healing elastomers to create haptic skins in the form of dielectric actuators.  By combining the self-healing elastomers with custom design approaches we also show higher spatial resolution and a larger tactile response in comparison to existing approaches.  This allows for the creation of transparent, highly stretchable and self-healing haptic skins opening up their use in far more heavy use domains.   The market for haptic devices is large, and is estimated to reach $4. 5 billion by 2026.  This is particularly driven by the need for novel machine-human interactions in the automotive, industrial machinery and medical industries.  These market segments require reliable, robust haptic skins which can withstand high usage whilst providing a strong tactile response.  We believe our haptic skin will allow for implementation and use in these high value target markets allowing for haptic skins to be used in a wide range of new and exciting application areas. The aim of this project is to bring our haptic skin to market by: performing market studies to quantify the economic margin and identify most promising markets; establishing links with industrial partners and customers; developing and optimizing haptic skins for robustness and tactile response to meet the de