RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Protein oxidation in muscle foods: mechanisms, effects and development of antioxidant strategies' will create measurable scientific, societal and economic impact aligned with Sixth Framework.

assistant: **Impact**

The oxidation of food components is one of the main factors reducing meat quality regarding sensory traits, nutritional value and healthiness. Whereas the undesirable changes caused by lipid oxidation on muscle foods have been largely studied, scarce information regarding the occurrence of protein oxidation is available. Recent studies of protein oxidation in biomedical sciences have shed light on the mechanisms by which cellular proteins can be affected by free radicals leading to adverse biological effect s. The addition of antioxidants in foods is a commonly used method to reduce adverse effects of lipid oxidation. Lately, special attention has been given to natural antioxidants because of the worldwide trend to avoid synthetic additives. To this regard, increasing expectations have arisen due to the evidence that natural antioxidants could have further benefits because of their ability to inhibit biologically harmful oxidative reactions.Recent studies carried out by Estevez et al. (the candidate) reported novel and sound data on the occurrence of protein oxidative reactions in cooked meat products and reasonable mechanisms by which those would affect certain quality traits in muscle foods. Prof. Marina Heinonens group (host institution) has largely contributed to shed light on the mechanisms of protein oxidation in model systems. Promising studies have been carried out by both groups regarding the protective role of natural antioxidants against protein oxidation in model and food systems.Upcoming studies should deal with unknown aspects on this topic:a) precise chemical mechanisms and characterisation of protein oxidation products, andb) evaluation of the adverse effects of protein oxidation on a variety of muscle foods during production, handling and cold storage r
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Development and application of electronic quantum Monte Carlo methods to improve density functional theory' (QMC-DFT).

assistant: **Innovation**

The present project concerns developments in computational electronic-structure theory, which are relevant to theoretical chemistry and materials science.It aims at allowing the applicant to pursue the work he began to improve the multi-determinantal density functional theory (DFT) method proposed by Dr. Andreas Savin and coworkers, which, by combining a long-range conventional wave function calculation with a short-range density functional approximation, has the potential of curing the main shortcomings of present-day DFT.To do so, we want to extend to general many-electron systems the recently-proposed Overhauser method which, starting from approximate effective two-electron potentials, can produce very accurate short-range system-averaged pair densities (or intracule densities) and therefore very accurate short-range correlation energies, needed in the multi-determinantal DFT approach.For this purpose, we will need to develop and apply appropriate quantum Monte Carlo (QMC) techniques in order to access ac curate reference data.We plan to achieve three successive objectives:- extend and apply methods for obtaining very accurate energy-optimized QMC wave functions;- calculate accurate short-range intracule densities from those QMC wave functions for so me atomic and molecular reference systems;- determine the corresponding Overhauser effective two-electron potentials, and propose approximations to them.The first two objectives will be carried out during the outgoing phase at Cornell University (USA) with Prof. Cyrus J. Umrigar where the applicant will acquire the necessary knowledge in QMC simulations, while the third objective will be done during the return phase at the University of Paris 6 (France) with Dr. Andreas Savin.The fellowship will allow the applicant to br
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Mineral excavation by photosynthetic microbes, a geochemical survey of a biological paradox' demonstrating excellence, impact and implementation quality for a Seventh Framework call.

assistant: **Abstract**

This interdisciplinary proposal aims to make important contributions in the field of microbes-mineral interactions using as model system the boring process of endolithic cyanobacteria. Cyanobacteria are photosynthetic bacteria which count among the most common, widespread and environmentally significant agents of bio-erosion, boring microscopic galleries as they grow within carbonate substrates. The mechanisms by which they achieve this against chemical equilibrium are poorly known. This project objective is to better understand mechanisms involved in cyanobacteria boring activity, detail, its phylogenetic distribution and to characterize the mineral and geochemical signatures of this process, so as to be able to apply it in the interpretation of paleobiological records.This will be achieved by studying laboratory cultures of cyanobacteria, performing boring assays in various substrates, and monitoring the boring activity. Diverse tools from molecular biology, microbiology and geochemistry will be used including confocal laser scanning microscopy, electron microscopy and secondary ion mass spectroscopy. That all together will allow in-situ survey of intracellular and extracellular chemistry variations, the identification of molecular bases of the process as well as the nature and distribution of mineral phases and organic. This will help to refine microbial and mineralogical models for the mechanisms involved, and to assess the quantitative importance of boring cyanobacteria in present and past ecosystem.My goal with this proposal is to establish a truly interdisciplinary expertise in the study of endolithic cyanobacteria by joining the skills and tools of the Garcia-Pichel lab (ASU-USA) and Biogéosciences lab (uB-France). This project will be a unique opportunity to be
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Causes and MEchanisms foR non-atopic Asthma in children', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

Until 20 years ago it was widely believed that asthma was an allergic/atopic disease involving atopic inflammation of the airways. Work that I and others have done has now shown that non-atopic asthma is much more important than was previously recognised. This has been confirmed by my ERC-funded AsthmaPhenotypes study, in both high-income countries (HICs) and low-and-middle-income countries (LMICs). This is important both in terms of the prevention of non-atopic asthma, and also in terms of its treatment.I therefore propose to study the Causes and MEchanisms foR non-atopic Asthma in children (CAMERA) in four different settings where I have shown that NAA is common: New Zealand (HIC, high prevalence), Brazil (LMIC, high prevalence), Ecuador (LMIC, medium prevalence), and Uganda (LMIC, low prevalence). Work-package 1 (WP1): involves a case-control study of risk factors for atopic and non-atopic asthma in these four settings, as well as similar analyses in other available and comparable data sets. Together, these studies have comparable data on asthma, atopy, and a large number of asthma risk factors, on a total of 48,000 participants. I will conduct innovative analyses exploring the different causal pathways in these different settings.Work package II: in each centre, we will then select 160 participants (40 atopic asthmatics, 40 non-atopic asthmatics, 40 atopic non-asthmatic, 40 non-atopic non-asthmatics) for further clinical investigation with regards to three mechanisms that may be particularly relevant to non-atopic asthma: capsaicin challenge, cold-air challenge, and response to interferon-gamma. The unique features of this study include: (i) the inclusion of both high and low prevalence centres from HICs and LMICs; (ii) new analyses of risk factors for NAA, contrast
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Early Stage Investing Launchpad - Unleashing the potential of early stage investing in Europe', explaining its relevance to EU policy priorities under Horizon 2020.

assistant: **Impact**

ESIL will establish an EU Framework for capacity building for early-stage investors in Europe, facilitating the take up of Angel Investing, overcoming obstacles related to market outreach and engaging key actors e.g. entrepreneurs, unconventional early stage investors and crowdfunding.To maximise impact ESIL will deliver dedicated actions, tools and mobilise expertise for every investor at any given stage of his/her experience, from awareness to actual investment to ""bring on board” local and international investment capacities, increasing the conversion rate in the journey from the awareness raising to the actual investmentsESIL will use state of the art on line material and best in class technology platform, but at the same time will engage top Business Angels in intimate events with local champions boosting the process in an informal, peer2peer fashion especially in countries with a younger Angel marketThe potential is huge, even if we want to count on the most optimistic estimates of 250k business angels today active in Europe this is still far from e.g. the 3mln HWNI Europe can count onESIL will take special care of less developed market, transferring and adapting all the knowledge of its partners but will also work on improving the more developed market that have big challenges such as illiquidity and co-investmentsESIL will target all the members of local BA groups, as well as individual investors, successful entrepreneurs, institutional players in EU28 and H2020 Associate CountriesConnecting ecosystem actors (including policy makers) and investors and demonstrating how this pays off will contribute to short-term impact and sustainability. The interaction among different communities and typology of stakeholders (for profit and not for profit, conventional and un
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Do extreme climatic events facilitate plant invasions?' under Horizon 2020.

assistant: **Concept**

Extreme climate events (ECEs) are projected to increase in magnitude and frequency as global warming intensifies the global water cycle. Global warming is also changing species distribution patterns by affecting native plant communities and by enabling alien species to expand beyond their native range. We increasingly realize that climate change and biological invasions act together, leading to even more dramatic outcomes. However, how ECEs will affect the incidence and strength of biological invasions remains poorly understood. Therefore, the overall objective of EXTREME is to develop a mechanistic understanding of how increased climatic variability and ECEs affect alien plant invasions. I will relate the incidence of species invasiveness with climate variability and the occurrence of ECEs, using drylands as study system. A novel approach to develop further understanding is the inclusion of genomic features in explaining the response to ECEs. A modelling approach will be combined with a common-garden experiment to study the effect of drought and heavy rainfall on the performance of native and alien plant species in a model dryland system in South Africa. EXTREME will allow me to diversify my individual competence by acquiring new skills (statistical and climate modelling and GIS) and competencies (academic leadership, proposal writing, project management). EXTREME will strongly benefit my inter-sectoral and interdisciplinary expertise and strengthen my international network, which is also beneficial for the host. A two-way transfer of knowledge is guaranteed since EXTREME combines my expertise in invasion and evolutionary ecology with the host’s expertise in the effect of climate variability and extremes. Therefore, EXTREME is not only expected to catalyse my career de
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'Inclusive DIALOGUES towards an operational concept of energy citizenship to support the Energy Union'.

assistant: **Concept**

DIALOGUES will support the Energy Union with operational research on energy citizenship that enables citizens to take a central role in the energy transition. To reach this objective the project will operationalise, contextualize, measure, and support the framework environments, policies and institutions that allow deep, inclusive energy citizenship to emerge. The key focus of DIALOGUES is on co-creating energy citizenship innovations that include the perspectives of groups currently on the margins of the energy transition such as, women, low-income households, energy poor, and ethnic minorities. DIALOGUES central methodological pillar is grounded in tested inter- and transdisciplinary techniques, with a spotlight on open innovation and co-design of the research process through novel Citizen Action Labs in 8 countries. For the policy and research communities, DIALOGUES will move the idea of energy citizenship forward to an operational concept that offers actionable policy insights, applied research tools and a unifying theory for citizen-oriented energy research. The project will develop tools to measure the degree, and map the modes, of expressing energy citizenship, related KPIs, a policy decision tool, and a Knowledge Platform linking all project data and results. Policymakers & stakeholders from the DIALOGUES levels of analysis: community, local/regional, and national/supranational, will be included through co-creative workshops and policy briefs. A Policy Advisory Group of leading energy experts, research centres and institutions, local governments, city networks and NGOs will frame the DIALOGUES research process to ensure maximum impact on all geo-political levels. The project will foster deep, multilateral exchanges with the 72 supporting organisations, in 13 nat
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Fourth Framework proposal on 'Generic avionics scalable architecture'.

assistant: **Innovation**

Objectives and content Implementation of CNS/ATM functionalities on-board aircraft in order to allow airlines to operate in the ICAO FANS environment will have a major impact on current avionics equipments and architecture due to the fact that the added functionalities (and mainly those relative to Flight Management and to Communication Management) will exceed the capacity of current airborne computers (in particular FMS). Therefore software but also hardware updates and consequently new equipments are required for allowing CNS/ATM integration. The objective of this project is to define and to validate through a demonstrator a generic scalable computing architecture which could be used as a general purpose multi-applications computing platform into avionics providing CNS/ATM functionalities and, as expected, other avionics functionalities, with particular emphasis on passenger revenue aircraft (AIRBUS, ..). This approach which is in line with the new ACR (Avionics Computer Resource) concepts, decouples the application software which will provide the avionics functionalities from the underlying hardware platform. This will allow airlines to gradually implement CNS/ATM software functions with potential mixed levels of criticality, independently from any specific hardware platform, with the expected result to reduce certification efforts within existing and future aircraft. This approach is viewed as being realistic and beneficial considering that the FANS operability will come about in phases and necessitate incremental updates to the software programs to transition into each new phase of FANS. The first phase of the project is intended to refine user requirements in terms of operational, support, functional as well as certification needs. Review of current work on Advanc
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Electrophilicity-Lifting Directed by Organochalcogen Redox-Auxiliaries and Diversiform Organocatalysis' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

The implementation of viable practices for the ecologically cognizant production and consumption of energy and renewable resources rank among the most pressing societal challenges of the 21st century. Against this background, the design and development of innovative concepts for the sustainable use of energy and energy-rich compounds from regenerative sources becomes a matter of profound technological and scientific pertinence. A promising approach that has been put forward in the context of chemical synthesis is the application of visible light as an inexpensive source of energy and air as an abundant and gratuitous oxidant for the derivatization of certain hydrocarbons. Despite the enormous economic and ecological benefits associated with the use of light and air as integral components of redox reactions, the realization of such processes is strikingly limited to very isolated applications. Consequently, this methodological deficit represents a momentous opportunity for modern chemical sciences to lastingly transform the routine lines of action for the oxidative manipulation of organic molecules. A key issue that needs to be taken into consideration for the design of efficient light-driven aerobic oxidation protocols is the identification of proper catalyst systems that allow for the site- and chemoselective activation of individual bonds within polyatomic frameworks. In this regard, the prime objective of the proposed research program is the rational design of non-metallic and in part cooperative catalysis regimes as enabling technologies for the electrophilic activation of non-aromatic carbon–carbon multiple- and carbon-chalcogen single bonds to facilitate a wide and diverse array of heretofore unprecedented oxidative coupling-, addition-, and rearrangement reaction
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'innovative Medical Protons Achromatic Calorimeter and Tracker' (2014-2020).

assistant: **Concept**

The iMPACT project focuses on the realization of a proton Computed Tomography (pCT) scanner capable of acquiring a target full 3D image with 1s exposure, therefore opening the way to the practical application of proton imaging technique in medical radiotherapy treatments. Such cutting-edge particles scanner combines innovative ideas devised for the future High Energy Physics experiments together with original developments in the microelectronic field to enable charged particles imaging at the GHz scale.     In recent years the use of hadrons (1H and 12C ions) for cancer radiation treatment has become an established technique and many facilities are currently operational or under construction worldwide. To fully exploit the therapeutic advantages offered by hadron therapy, precise target (body) imaging for accurate beam delivery is decisive. pCT systems, currently in their R&D phase, provide the ultimate in low dose (< 2 mGy), 3D imaging for hadrons treatment guidance. Key components of a pCT system are the detectors used to track the protons and measure their residual energy.The iMPACT scanner, composed by a proprietary monolithic pixels tracking detector and an innovative achromatic calorimeter, will improve current pCT imaging speed by more than a factor 100, leading to potential recording times of about 1 second for a full 3D target image (compared to present ≈ 10 minutes). The iMPACT detector will also have higher spatial resolution (equal or better than 10 µm) and lower material budget (by a factor 10) respect to state of the art systems, further enhancing 3D imaging accuracy. Not least when considering actual industrial application, production costs will be far lower than existent systems, because all sensors will be designed with commercially available technologi