RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'The Dust-Gas Synergy in the ISM' (SYNISM), addressing dissemination and exploitation.

assistant: **Impact**

Interstellar dust is a fundamental component of the interstellar medium (ISM). By mediating key processes such as the absorption of stellar radiation, which is then re-emitted at infrared-mm wavelengths, it provides the necessary conditions (e.g., cloud cooling) for star formation to occur. Thus, dust determines the very processes that govern galaxy evolution.  Dust is a ubiquitous component of the ISM in nearly all types of galaxies, even those at very high redshifts, where the dust has had little time to form.  However, dust is an evolving component of the ISM, which responds to the local conditions.  If we are to understand the processes that govern galaxy evolution it is therefore essential that we understand the evolving nature of dust in its relationship with the physical and dynamical conditions of the local ISM. The aim of this project is to study the evident synergy between interstellar gas and dust and to quantify the factors that drive dust evolution. This will be achieved by combining observations of a sample of photo-dissociation regions covering a range of local physical conditions, using the unique capabilities from ESA's newest IR space observatory, the Herschel space telescope, together with cutting edge expertise.""
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Deep brain targets for neurostimulation in affective disorders' in the context of a Horizon 2020 call.

assistant: **Objectives**

Objective: The overarching goal of proposed project is to provide necessary knowledge about neurobiology of Major Depression Disorder (MDD), which would lead to higher efficacy in treatment of this affective disorder. The research objectives of the action are 1) identification of electrophysiological biomarkers of functional brain abnormities in treatment resistant depression (TRD) and 2) suggestion of novel targets for neurostimulation in patients with TRD.Methods: Twenty patients with major Depression Disorder (MDD) and 20 healthy controls will undergo a resting-state high-density EEG recording (HD-EEG). Microstate analysis will be performed to identify possible biomarkers of functional brain abnormity in MDD. Source activity will be obtained for regions of interest (ROI) using individual head model and a distributed linear inverse solution. Directed functional connectivity using Granger causal modelling will be applied to the source signals of ROI to identify abnormally interconnected nodes.Relevance: If new biomarkers of functional brain abnormity in MDD are identified, better characterisation of pathophysiology of depression will be made. If abnormal nodes of large-scale brain neuronal network are identified, new and individually specific targets for deep brain stimulation (DBS) will be suggested. These findings will support future implementation of highly individualised DBS treatment of TRD.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon 2020 proposal on 'Studying RNA-binding proteins involved in neural differentiation and degeneration'.

assistant: **Innovation**

RNA-binding proteins (RBPs) coordinate post-transcriptional regulation immediately after transcription by RNA-processing, nuclear export, localization, stability and translation rate of RNAs. The importance of these RBPs in neural development have been underscored by detecting their mutations in severe neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS), ataxia or tremor. In this project, using the assays that I developed specifically for the identification of RBPs I want to track down novel RBPs involved in neural differentiation. I will use patient-derived induced pluripotent stem cells (iPSC), as model system to discover RBPs that their malfunction may lead to neurodegeneration. Furthermore, I will identify the binding targets of the RBPs to determine the pathways that are affected. Finally, using machine-learning methods I will integrate these data to shed new light on the mechanism of neural differentiation and degeneration. The output of this project in long term will help to identify individuals at risk, and to develop better therapeutic approaches to treat neurodegenerative diseases.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon 2020 proposal on 'CAPTURING AND REPRODUCTION OF CROWDED ACOUSTIC ENVIRONMENTS FOR IMMERSIVE APPLICATIONS'.

assistant: **Concept**

CROWDMERSE enables real-time capture, processing, and reproduction of an immersive audio experience to the user of any event of interest, focusing on “crowded” acoustic events. Acoustic scenes with large audiences, such as sports events or music concerts, present significant challenges for immersive reproduction which have not been so far adequately considered in the signal processing community. Technological breakthrough in sports events broadcasting has a strong potential impact on media providers, and consequently on the European and global economy. The challenges of capturing and reproducing crowded acoustic events include the need to spatially capture and reproduce numerous sound sources, such as the applause and yells of the spectators, in addition to the “main” sounds of the event. Concerns regarding the privacy of the spectators must not be overlooked: the conversations of the audience members sitting near the microphone sensors must be eliminated. In order to spatially sample large venues, the acoustic sensors should be low-cost, small-sized, and support wireless operation. The developed algorithms should respect the limited sensor resources, while operating in real-time to enable commercial applications. Our final objective is to enable real-time delivery of crowded acoustic events so that the designed platform can be integrated with today’s High-Definition TV programs. CROWDMERSE focuses on sound capturing using multiple closely placed microphones forming a microphone array. The audio content is rendered through a home entertainment system equipped with multiple loudspeakers, accompanying the content of a typical HDTV broadcast. Addressing the scientific challenges and proposing a solution which can be integrated with current broadcasting principles is guaran
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Unlocking the secrets of remote memories: dissecting the cortico-hippocampal engram'.

assistant: **Concept**

Every day we form memories based on experience. These memories undergo a selective process, during which some become long-lasting memories while others fade away.Memory age can be distinguished based on the neuronal systems engaged during different stages: recently acquired detailed memories rely on the hippocampus (especially CA1),while remotely acquired, more generalised memories depend on cortical activation(specifically the anterior cingulate cortex, aCC). However, our understanding of how certain information from the original event is selected to migrate from one region to the other, while other is lost, remains limited.We aim to explore whether these two regions attend to different information during memory acquisition. To accomplish this, we will employ FliCRE, an innovative optogenetic tool that offers precise temporal control over the tagging and manipulation of cells through both calcium signalling and light activation. This groundbreaking technology allows us to attain an unprecedented level of temporal precision, enabling differential labelling of cells that encode distinct information, such as when a mouse is exploring an environment versus experiencing a footshock or freezing.By tagging and manipulating these diverse populations in CA1 and aCC, we will track their recruitment at different time points. This investigation seeks to shed light on why memory age influences our perception of the original experience differently. By understanding the underlying neuronal mechanisms, we may find ways to reverse this effect, offering a potential approach to help treat maladaptive memories. Our research holds promise in unravelling the complexities of consolidation and its implications for memory therapies.


**Keywords:** remote memory, engrams, FliCRE, circuits, inf
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'IMPACT OF COLOSTRUM-BASED NEUTRACEUTICALS ON FUNCTIONAL GASTROINTESTINAL DISORDERS' will create measurable scientific, societal and economic impact aligned with Seventh Framework.

assistant: **Impact**

The aim of this proposal is to create a multiannual joint programme of collaboration between research-intensive non-commercial (academic) and commercial (industry) organisations to increase knowledge on the effects of colostrum-based neutraceuticals on functional gastrointestinal disorders (FGID). Functional gastrointestinal disorders such as irritable bowel syndrome represent well-known issues, yet the vast majority of attempts to address them to date have been led by either the public or the private sector alone. The current proposal is designed to exploit the complimentary expertise of non-commercial and commercial organisations through knowledge sharing and transfer between sectors. This will be achieved by establishing a Network of Excellence (NoE) that will incorporate staff secondments and the recruitment of researchers from outside the partnership for the purpose of networking, training activities, workshops, and joint research. Thus, this proposal will foster mutual understanding of the different cultural settings and skill requirements of the non-commercial and commercial sectors, encouraging entrepreneurship and long-term intersectoral collaboration regarding the effects of colostrum-based neutraceuticals on functional gastrointestinal disorders. Eventually, this partnership may help translate creative ideas into innovative products and processes that can efficiently address existing challenges on gastrointestinal issues.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon Europe proposal for the project 'SUSTAINABLE CAREERS FOR RESEARCH EMPOWERMENT 2'.

assistant: **Objectives**

The SECURE2 project aims to pilot and implement recommendations from the European Framework for Research Careers (RCF) to improve research career progression and mobility within research-performing organizations (RPOs) and research-funding organizations (RFOs). This project builds on the previous SECURE project and expands its scope to a four-year duration, allowing a more extensive and impactful implementation of RCF recommendations. SECURE2 will provide a 2+-year trail within the 4-year project, to effectively implement the more difficult and time-intensive actions and recommendations.The overarching Aim of SECURE2 is to:•Build upon the completed ERA50 project SECURE, using SECURE expert partners and the pilot RPOs and RFOs experience in implementing Action Plans (APs) for institutional change.•Use and adapt best practice tools from the SECURE project, in particular, the ‘RCF Actions selection’ tool as the basis of guiding the pilots to select their interventions. •Foster the development of ecosystems for research positions by promoting collaboration between researchers, research managers, and administrators, facilitating active participation from all stakeholders, and ensuring that the co-design, implementation, and evaluation of the RCF are rooted in the practical needs of both academic and non-academic sectors.SECURE2 employs a three-tiered approach to ensure representation and consensus building of key stakeholder groups in the research and innovation ecosystem: (1) large consortium ensuring expert partners (2) open consultations with the stakeholder community to co-design and validate key project outcomes (3) advisory board of key representatives to ensure independent expert oversight and connection to policymakers.


**Keywords:** Research careers, RCF, HRS4R, c
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'Concept and Approach' section for a Horizon Europe proposal on 'Recovering plasma-facing components temperatures in fusion devices from IR camera measurements'.

assistant: **Concept**

Infrared (IR) cameras are key diagnostics to monitor and control plasma-facing components (PFCs) in fusion devices. Nevertheless, the use of all-metallic PFCs with low and variable emissivity ( ~ 0.1-0.5) makes it difficult to obtain a correct surface temperature measurement. The radiance collected by the IR camera includes both the thermal radiation emitted by the target and parasitic radiation coming from the target's surroundings. Furthermore, target emissivity changes with the surface temperature and roughness. This causes significant errors in the surface temperature measurement that we need to address for achieving high power and safe plasma operation. Inaccurate interpretation of IR temperature measurement could endanger machine safety (temperature underestimation) or on the contrary, lead to unnecessary pulse interruptions that reduce the overall performance of the machine (temperature overestimation). The current approach is to convert the radiance collected by each pixel in an apparent using a physical relationship between emitted radiance and temperature (Plancks law). Because a portion of the collected radiance is due to reflection on the target, a systematic error is made. This method is unable to recover the portion of reflected radiance and to deduce the correct temperature of the target using only the emitted radiance. The proposed technique in this project is to use a digital twin of the machine and to make in it assumptions on the temperatures of the different elements of the machine in order to simulate the images that would be measured under these supposed conditions. By comparing to the real image measured by the camera and using optimization techniques, the assumptions on the parameters can be updated until the simulated and measured images are clo
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Neuroscience Early Stage Research Training' will create measurable scientific, societal and economic impact aligned with Sixth Framework.

assistant: **Impact**

Despite major advances in molecular, cellular and systems neurobiology, the greatest challenge of modern neuroscience has yet to be met: The development of causative therapies for psychiatric, neurological and neurodegenerative disorders. This goal of EU health policies is of prime socio- economic importance and can only be achieved on the basis of major research efforts into basic and applied neurobiology/neurophysiology. On the other hand Europe presently faces a lack of neuroscientists who have undergone advanced and multidisciplinary training that covers broad areas of neuroscience. It is therefore mandatory that high-quality training programs be implemented in Europe to educate future neuroscientists at the highest level. The Max Planck Institute for Biophysical Chemistry in Getting, together with its partners, the University of Getting, the European Neuroscience Institute, the Max Planck Institute for Experimental Medicine, the German Primate Centre, and several research-oriented local companies, are in a unique position to provide such training in Getting. The neuroscience faculty of these institutions has therefore agreed on implementing an international training program for protectoral neuroscientists that is founded on cutting-edge research. 40 faculty members, many of them internationally renowned scientists, will join forces in its implementation. The program will provide structured training in a wide area of advanced methods of neurosciences and offer choices that are available only at very few places around the world. Furthermore, the program will provide education in complementary skills such as scientific presentation and writing, teaching, and project management, encouraging young researchers to embark on long-term research careers.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Neuromuscular assessment in the elderly worker' will create measurable scientific, societal and economic impact aligned with Fifth Framework.

assistant: **Impact**

Neuromuscular (NM) problems reduce working ability of aging workers, and increase cases of work loss and accidents. For this reason, elderly people throughout Europe are forced into early retirement and fail to be self-supporting. There is a need to identify and monitor work related NM disorders in order toa) reduce their consequences by monitoring the most vulnerable individuals,b) identify the determents of NM aging related to occupational conditions andc) evaluate methodologies for warning elderly workers when there is insufficient relaxation in vulnerable muscles. Preliminary results show the possibility of identification of NM problems through non-invasive techniques, recently developed within the SENIAM and PROCID Concerted Actions, which can provide quantitative indices of NM performance. Substantial field tests and training initiatives are required to demonstrate that these techniquesa) can be used outside the research labs and may have a European market in the fields of ergonomics and occupational health andb) can be routinely used to monitor the relationship between occupational and NM system conditions in the working environment Standardization of mythology is needed.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Evolutionary Stability of Ubiquitous Root Symbiosis' to be submitted under Horizon 2020.

assistant: **Abstract**

Virtually all terrestrial plants depend on symbiotic interactions with fungi. Arbuscular mycorrhizal (AM) fungi evolved over 450 million years ago, are obligate biotrophs and cannot complete their lifecycle without obtaining carbon from host roots. Mediating nutrient uptake and sequestering carbon in soil this symbiosis lie at the core of all terrestrial ecosystems. Plants on the other hand are facultative mycotrophs but under natural conditions all host roots are colonized as a result of multiple beneficial effects of AM fungi. In the symbiosis, both plants and fungi are promiscuous, forming interactions across individuals and species. In the absence of host-symbiont specificity and given their inability to discriminate among partners prior to interaction, evolutionary theory predicts that “free riders” would evolve and spread. Yet AM fungi remain evolutionary and ecologically successful. I propose that this is thanks to their unique genomic organization, a temporally dynamic heterokaryosis.Unlike other eukaryotes, AM fungi have no single nucleate stage in their life cycle, instead they reproduce asexually by forming large multinucleate spores. Genetic variation is high and nuclei can migrate and mix within extensive mycelial networks. My group has recently established a single nucleus genomics method to study genetic variation among nuclei within AM fungi. With this method I can resolve the extent of heterokaryosis in AM fungi and its temporal dynamics. I will study the emergence of “free riders” upon intra organismal segregation of genetically distinct nuclei during AM fungal adaptation to host. Further I will study how hyphal fusion and nuclear mixing counteract segregation to stabilize the symbiosis. The research program has great potential for novel discoveries of