RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Atlantic sea level rise : adaptation to imaginable worst case climate change' (ATLANTIS) under Fifth Framework.

assistant: **Objectives**

We will adopt methodologies of risk management to study adaptation to imaginable worst case Climate change. In consultation with local experts and stakeholders, we will develop rich scenarios (future histories") of the societal implications of a 5-6 metre sea level rise, potentially caused by a collapse of the west-Antarctic Ice Sheet , on the Rhone delta , the Netherlands and the Thames Estuary. We will estimate the amount of land, buildings etc lost, but will focus on initial responses (e.g., dike building, managed retreat), their probabilities of failure, as well as the wider effects (e.g., on the economy, large-scale migration). In addition, we will perform a formal risk assessment, analyse social representations and investigate optimal control of greenhouse gas emissions under catastrophic risk. The project would add substance and seriousness to the debate of potential catastrophes that may be caused by human-induced climate change."
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'REPAIRING ERRORS IN COMPUTER AIDED LANGUAGE LEARNING' under Fourth Framework.

assistant: **Concept**

RECALL is working towards more adequate and user-oriented software for computer-aided language learning by investigating intelligent feedback facilities as an enhancement to an existing commercial prototype. Prospective end-users include tutors and students, educational CD-ROM suppliers and corporate training departments. The system will enable the proficiency and strategies of individual learners to be dynamically profiled. It will detect errors in their input and offer feedback helping them to understand and avoid recurrence of their mistakes.RECALL has investigated the requirement to provide error correction as an enhancement to a prototype CALL package. The facility detects errors made by students and provides them with feedback in a way which helps them to understand the nature of their mistake and to learn from it. Such a facility is designed to offset the lack of flexibility and feedback in current systems. The project has enabled progress towards more adequate and user-oriented CALL software by taking account of individual learner strengths and weaknesses, levels of proficiency, and preferred learning strategies. It will serve as a pilot study for future activities in the area of intelligent CALL applications. The package incorporates a module that provides detailed linguistic analysis of the learner's response to exercises (a diagnosis component), a module that creates a dynamic model of the learner, representing his learning history (a learner model), and a module that controls the system's reactions to the learner's input and the structure of materials offered (a tutor model). Progress In the first year, work focused on a market survey and user requirements. A preliminary market report, based on the results of primary and secondary research was then finalised
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Quantum-enhanced nonlinear imaging' (QuNIm), addressing dissemination and exploitation.

assistant: **Impact**

Many pioneering advances in medicine and biology require observation of the microscopic world with high resolution and without damaging the specimen. One of the most widespread techniques is multiphoton fluorescence microscopy, which allows full 3D imaging via optical sectioning, i.e., imaging of planes within the sample without the need for physical slicing. This technique has a major limitation, however: the penetration depth and the signal-to-noise ratio are not sufficient for imaging deep within tissue, preventing functional imaging of, e.g., neuronal or cardiac activity beyond superficial layers.QuNIm aims to transform the field of nonlinear imaging and microscopy by exploiting the unique properties of entanglement, a quantum mechanical superposition of two or more photons that behave like single particles. Two quantum-correlated photons are absorbed in a nonlinear process as a single particle, an event 10 billion times more probable than the absorption of two classical photons. QuNIm will apply, for the first time, the innovative concepts of spatiotemporal and multimode entanglement, super-Poissonian fluctuations, and macroscopic quantum beams to deliver a ground-breaking imaging technique. It will maintain the strengths of standard nonlinear imaging (e.g., multiphoton microscopy, boasting high resolution, 3D imaging and molecular specificity using fluorophores/photoproteins) while increasing its penetration depth and removing the drawbacks (complex ultrashort pulsed lasers, lengthy scanning procedures, and phototoxicity).QuNIm will further extend the limit of deep-tissue imaging while at the same time enhancing the contrast and reducing the laser intensity (mitigating tissue damage), delivering a transformative impact in different fields. For example, in neurosci
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose the 'State of the Art and Innovation' section for a Horizon Europe proposal on 'Private Law Firms as Transnational Advocates'.

assistant: **Innovation**

Top private law firms increasingly offer their services as advocates for societal needs at no or low cost—big law pro bono. This work changed significantly over the past decade: firms take on more pro bono activities, professionally organize those in-house, and do so over a wider geography, in particular the Global South. While traditionally engaging in litigation, pro bono lawyers have now expanded towards the full range of activities of transnational advocacy: they train and educate stakeholders, they advise international institutions and non-profit organizations, and they engage in institution-building. To do so, they rely on powerful resources, not least lawyers who went to the best law schools, ever-increasing revenues, and highly influential networks. However, we lack systematic knowledge on how big law does good and with which implications for transnational advocacy.PROBONO is the first project to tackle this key research question at a crucial point in time. The project’s claim is that big law pro bono is crowding NGOs and local organizations out of their traditional advocacy space. These firms are not affected by the shrinking space observed for traditional human rights defenders and they are both accustomed to and better equipped for navigating democratic backsliding and authoritarian contexts. As these firms gain exclusive influence on law- and policy-making across levels, they change the organizational ecology of the field—with as yet unknown consequences. This project studies the patterns, practices, and consequences of private law firms as transnational advocates. It collects and analyses unique quantitative data and conducts in-depth qualitative case studies on big law pro bono for women’s rights and the right to a healthy environment. PROBONO significantl
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Restoring DNASEs antiviral potential' to be submitted under Horizon Europe.

assistant: **Abstract**

Every individual carries at least a herpesvirus causing mild to serious diseases without definitive cure. Although in theory, herpesvirus genomes can be degraded by host DNA nucleases (DNASEs), the ER preliminary data has evidenced DNASE2B protein levels to decrease upon herpes simplex virus-1 (HSV-1) infection. In order to restore DNASEs anti-viral potential, REDAVIP aims to 1) uncover the susceptibility of DNASEs to HSV-1, 2) gain mechanistic insights of HSV-1 proteins and DNASEs interaction, and 3) screen drugs restoring host DNASEs so the vDNA can be cleared from the organism. To do so, REDAVIP will assess DNASEs’ endogenous levels upon infection by immunoblot and enrich them with immunoprecipitation to identify interacting viral protein(s) by mass spectrometry collaborating internationally. Afterwards, their minimal interacting surfaces will be determined and disrupted with in silico drug library screens collaborating internationally. Then, a tripartite fluorescence complementation assay will confirm the disruption of this pathogenic interaction in cellula. Candidate compounds restoring the DNASEs ability of degrading vDNA will be validated by plaque assays for IP protection, since they may represent a first step towards an overdue cure against herpesviral infections and life quality improvement, especially for an ageing population. Given the ambitious and novel objectives, the ER applies her multidisciplinary expertise to propose mitigation strategies that will ensure experimental feasibility and multiple outputs. This work will allow the ER to transfer her knowledge acquired through European laboratories to the acceptor institution, and progress from basic to translational research to learn and ensure a revenue of invested funds. The findings will be broadly diss
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Peptide-derived bioavailable macrocycles as inhibitors of protein-RNA and protein-protein interactions' (PEP-PRO-RNA).

assistant: **Concept**

The objective of this proposal is the elucidation of general principles for the design of bioavailable peptide-derived macrocyclic compounds and their use for the development of inhibitors of protein‒protein (PPI) and protein‒RNA interactions (PRI). Over the last decade, drug discovery faced the problem of decreasing success rates which is mainly caused by the fact that numerous novel biological targets are reluctant to classic small molecule modulation. In particular, that holds true for PPIs and PRIs. Approaches that allow the modulation of these interactions provide access to therapeutic agents targeting crucial biological processes that have been considered undruggable so far.  Herein, I propose the use of irregularly structured peptide binding epitopes as starting point for the design of bioactive macrocycles. In a two-step process high target affinity and bioavailability are installed:1) Peptide macrocyclization for the stabilization of the irregular bioactive secondary structure2) Evolution of the cyclic peptide into a bioavailable macrocyclic compoundUsing a well-characterized model system developed in my lab, initial design principles will be elucidated. These principles are subsequently used and refined for the development of macrocyclic PPI and PRI inhibitors. The protein‒protein and protein‒RNA complexes selected as targets are of therapeutic interest and corresponding inhibitors hold the potential to be pursued in subsequent drug discovery campaigns.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Smart and Proactive Multi-RAT Traffic Steering for V2X' in the context of a Horizon Europe call.

assistant: **Objectives**

Connected and autonomous vehicles (CAVs) have the potential to provide efficient and sustainable transportation. However, road safety of autonomous driving remains a critical challenge, the lack of which hinders their widespread adoption and integration into the transportation system. It is thus pressing to evolve vehicle-to-everything (V2X) communications to provide reliable and secure communications for CAVs to exchange critical information for cooperative decision-making, ensuring the road safety. This project sets an ambitious goal of designing smart and proactive traffic steering across multiple radio access technologies (multi-RAT) in the environment of CAVs. The technical approach is threefold. First, to ensure the reliability of communications, this project unleashes the full potential of massive sensing that involves the collection of vast amounts of data from sensors deployed on vehicles and roadside infrastructure, and then leverage the cooperation perception of environment for situational awareness and ahead-of-time decision-making in V2X. Second, it develops a security and privacy preservation mechanism to protect the integrity and privacy of the highly dynamic vehicular network as well as defending the widely used machine learning process. Finally, relying on the 5G testbed, Open RAN (O-RAN) solution, and other V2X facilities provided by some partners, the final step is to implement and evaluate the performance of developed solutions, which closes the gap between theory and practice. The planned secondments provide partners the opportunity to test their solutions on the infrastructure possessed by other partners.


**Keywords:** V2X Communications, mmWave Sensing, Security and Privacy
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft the 'Objectives and Scope' section of a Horizon 2020 proposal for the project 'Molecular mechanisms controlling exit from mitosis'.

assistant: **Objectives**

Cancer, the uncontrolled division and spread of cells, represents one of the most important causes of death in Europe and all over the world. Understanding how cells control their division is the key to comprehend and cure cancer. Eukaryotic cells divide through mitosis to produce new cells with identical DNA. Yet, mitosis has to be ended for the two cells to be separated to become individual cells with the capacity to further divide. This occurs by a process called mitotic exit. Mitotic exit is a critical step during cell division. Failure to control mitotic exit is the key cause of aneuploidy and genomic instability, which are hallmarks of cancer. Therefore, gaining a comprehensive knowledge of mitotic exit regulation will have significant impact on understanding and treatment of cancer. In this project, the researcher will uncover a novel mechanism that control exit from mitosis mitotic. This novel regulation has the potential to define a molecular target to fight cancer in long term. Researchers previous research experience puts her in a unique position to perform this project. This fellowship will also allow the researcher to build a successful academic career, to acquire new expertise and soft skills, and to establish future collaborations through dissemination, communication and training.  Furthermore with this fellowship, researcher will help increase public awareness of science through outreach activities.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Biofuel polygeneration system integrating MSW landfill gas and solar energy' in the context of a Sixth Framework call.

assistant: **Objectives**

The BIOPOLYSY proposal seeks to advance the development of innovative and readily applicable technologies to develop an efficient and competitive polygeneration system based on integration of landfill with solar system, reforming for the syngas production, ICE for electric generation and heating/cooling system for thermal energy requirements satisfaction.BIOPOLYSY demonstration project aims to encourage and promote the use of new, renewable energy sources do this mainly through demonstration activities involving polygeneration for energy and syngas production through the use of landfill gas and solar energy. The demonstration plant is planned in Slovenia. BIOPOLYSY also aims to create jobs within Europe and enhance the competitiveness of EU industry through increasing public and industrial awareness of polygeneration technology. Further advantages of the BIOPOLYSY solution include the reduction of CO2 emissions (a major aim specified in several EU directives and the Kyoto Agreement).
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Photoresponsive Smart Nanocarriers for Tetherless Regeneration of Bone Tissue' (PhotoNanoBone) targeting Horizon 2020.

assistant: **Abstract**

The research aim of PhotoNanoBone is to develop of a novel nanotechnological strategy based on stimuli-responsive nanocarriers together with a microfluidic platform for spatiotemporal control of cell reprogramming and differentiation of 3D cell cultures towards bone tissue engineering. The project entails three steps. (1) Synthesising stimuli-responsive nanocarriers by layer-by-layer assembly and loaded with cell reprogramming factors (cargo). Polymeric walls of nanocarriers will be further functionalized with magnetic and plasmonic nanoparticles. By applying magnetic fields, nanocarriers can be locally enrichment in 3D cell culture. Upon external light irradiation, plasmonic nanoparticles will be heated, leading to local opening of the polymeric walls and subsequent cargo release. (2) Set-up of a microfluidic platform for externally controlled intracellular magnetic targeting and light-triggered release of cargo. (3) Application of the developed technology in 3D cell cultures of fibroblasts (mouse model) for bone tissue engineering. I (the ER) will prepare, characterize and test the materials and application proposed, with the support of a multidisciplinary hub of specialists. The prime training aim of PhotoNanoBone is to provide me with a truly solid formation in biomaterials, which will support my future career endeavors, both in the academia or industry, to be an independent researcher, a founder of a start-up company or to become key player in the biomaterials sector. I will be hosted by the Centre for Research in Biological Chemistry and Molecular Materials (CiQUS) of the University of Santiago de Compostela, a cutting-edge multidisciplinary research center at the interface of chemistry, biomedicine and molecular materials. The training will be further strengthene
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write a project proposal abstract for 'Innovative Design Method for Matching the Pipe Organ to the Acoustics of the Room' to be submitted under Sixth Framework.

assistant: **Abstract**

Several pipe organs in newly built concert halls or churches are not well matched to the acoustics of the room. The resulted bad sound quality is dangerous for the organ builder SME because the negative opinion of a single costumer can destroy its market position. This project aims a cost reduction and quality improvement due to new developments which can improve the market position of the SMEs. As a result the number of orders of new pipe organs can be increased. So the SMEs will maintain or increase the number of their employees. The leading position of the European organ builders on the world market will be strengthened. In order to ensure an optimal matching, the knowledge of room and organ pipe acoustics and the tradition of organ building will be combined to a new, innovative design method. The degree of innovation is high, because the state-of-the-art method is based on the tradition only, whereas the new method would use and further develop up-to-date results from acoustics. The expected innovations are: New data and knowledge base of the emitted sound power of the most important pipe ranks: development of physical model of the dependence of the emitted power on wind pressure, shape and size of the pipe. New, scientifically based method and instrument for the measurement of room acoustical properties required by the organ builders: For the instrument, a very intensive low frequency (16-64 Hz) sound source and a sound source with simulated organ pipe sounds for the middle frequency range (64-512 Hz) will be developed. New measurement method and software will be made for the evaluation of the acoustic properties of the room from the view of the organ. New acoustic design method of pipe organs for optimal matching of the organ to the acoustics of the room: The wind