RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an executive summary for the EU project 'Interoperable solutions to streamline PED evolution and cross-sectoral integration' (PEDvolution) targeting Horizon Europe.

assistant: **Abstract**

The pinnacle of community driven urban energy transition are Positive Energy Districts (PED). They improve energy efficiency, integrate local renewables and excess heat more effectively and enable interaction with the energy and non-energy sectors like mobility, ICT and industry.A crucial, and often neglected complication is that PEDs are in constant evolution. This is due to ever-evolving changes in their environment: social context, legislation, energy market, increased electric vehicles, etc. As such, there is a strong analogy with the theory of evolution. Although the DNA between PEDs varies, the implementation and evolution of different PEDs is not a process of chance: the environment determines the probability of success in the urban energy transition.The PEDvolution project paves the way for cross-sectoral integration of ever-evolving PEDs. This over a duration of three years, consisting of three consecutive phases: analyse, co-develop and demonstrate. European pioneers in PED conceptualisation, implementation and tool development will co-develop and implement seven interoperable solutions accommodating the constant evolution of PEDs: 1) PED Design and Planning Toolset, 2) PED Readiness Assessment, 3) Dynamic Decision Support Guideline for PED Development, 4) PED Energy Manager, 5) Data Exchange, Integration and Interoperability Platform, 6) PED Business Models, 7) Social Innovation tool.These PEDvolution solutions will evaluate and improve the ‘PED Readiness Level’ according to the four genes of the PED genotype: social, technology, interoperability, and market. These are influenced by their interaction within the PED and its environment (PED phenotype).At least six real-life PEDs across Europe, will provide a demonstration and validation environment for the sol
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Dna & chromosomes 2002', explaining its relevance to EU policy priorities under Fifth Framework.

assistant: **Impact**

The objective of this proposal is to organise a high level multidisciplinary Euro Summer School on DNA and chromosomes. It is now clear that a full understanding of the structure and functions of DNA and chromosomes requires a multidisciplinary approach. Computer scientists for instance contribute to the analysis of genomic sequences or help deciphering gene expression using DNA chip technology. Physicists perform single molecule experiments on DNA, chromatin fibres and chromosomes, exploring unknown physical parameters and providing a new understanding of enzymatic catalysis. There is a growing understanding among molecular biologists that biology will in the future benefit from the knowledge accumulated in physics and in physical chemistry. This multidisciplinary approach that has led to important results in the past, is expected to have a growing impact in the next decade. Indeed, this field attracts an increasing number of researchers coming from various disciplines. As a result, there are strong training needs.The goal of the present school is precisely to participate in the training of young scientists willing to enter this exciting field. The goal of this high level scientific conference is to provide a comprehensive and state of the art set of lectures on the various approaches used to study DNA and chromosomes. It aims at facilitating the communication between researchers from various disciplines and at fostering the development of new collaborations.Extensive courses (2-4 hours) will be given by 20 invited lecturers chosen among the leading experts in their field. The course will be planned for a mixed audience (physicists, molecular biologists, etc) at the advanced PhD student/post doctoral level. The long duration of the courses will allow the speakers to be
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain how 'Rehabilitation and Reintegration in Europe' goes beyond current state-of-the-art under Horizon Europe.

assistant: **Innovation**

Until recently, the study of penal systems has focused mainly on their most severe or repressive features, but these systems often do great harm when aiming to do good, not least by expanding the scale, reach and intensity of penal control. For example, recent research suggests that ‘rehabilitation’ has become focused on managing risks rather than enabling reintegration and that, in consequence, it often hurts and harms those that it claims to help. By examining evidence from three countries that are often considered ‘progressive’ (the Netherlands, Norway and Scotland), the RaRiE project will help us better understand whether and where rehabilitation lives up to its ideals, and to creatively, critically and comparatively interrogate its development and prospects, its coherences and contradictions, its rhetoric and its realities, its pitfalls and its possibilities.  Through a new approach that I call Dialogical Comparative Penology (DCP), building on the interdisciplinary approaches that I have used in a series of innovative, high-impact research projects, RaRiE will provide a uniquely comprehensive analysis of the nature and impact of rehabilitation in these three nations. It will also develop new tools and metrics for critically assessing rehabilitative systems and practices, to better direct their future development. In and through dialogue with policymakers, senior leaders in prison and probation systems, practitioners, activists and people with lived experience of rehabilitation, RaRiE will help to improve the fairness and effectiveness of European penal systems. RaRiE’s ambition -- the ‘step-change’ it offers – lies both in developing a new approach to comparative penology, and in using that new approach to reshape how rehabilitation is understood and developed in
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Design of novel post-harvest technologies with low carbon footprint based on the discovery of active biomolecules' (FRUITPRINT) under Horizon Europe.

assistant: **Objectives**

A main challenge for human societies is to feed the ever-increasing world population while limiting the carbon footprint inherent in food production activities. These seemingly opposing challenges must be reconciled. Securing sufficient amount of food requires to master the post-harvest storage of fruit and vegetables, the main source of nutrient for human, especially if we aim to reduce meet consumption due to its high carbon footprint. Controlled atmosphere is the main technology used to extend shelf-life of fresh products. It is mainly based on low temperature and low oxygen that reduce metabolic activity of fruit and vegetables, but it is energy consuming with high carbon footprint impact. On the other hand, 1-MCP, a chemical that prevents plants from sensing the plant hormone Ethylene, is also widely used in post-harvest storage to block ripening and senescence. It has a non-discriminating effects on different ripening processes leading to some alteration of organoleptic traits. FRUITPRINT project aims to identify novel bioactive molecules to improve storage and limit post-harvest losses while reducing energy consumption. The project consists of 3 main steps: (1) identification of novel bioactive molecules inhibiting ripening and senescence by in silico and in vitro screens of large libraries of chemical compounds, (2) evaluation of the effectiveness of the selected bioactive molecules in post-harvest storage, and (3) uncovering the molecular underpinnings of their beneficial effects on fruit and vegetables physiology. FRUITPRINT project rely on multidisciplinary approaches and complementary expertise from partners on virtual screening, oxygen sensing, fruit physiology and post-harvest storage. It will build on original and innovative material such as high-throughp
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Predictive Maintenance for railway switches. Smart sensor networks on a machine learning analytics platform' will create measurable scientific, societal and economic impact aligned with Horizon 2020.

assistant: **Impact**

92.000.000 minutes, or 180 years. These are the, potentially avoidable, train delays caused by problems due to rail switches– every year, in Europe alone. The rail switch is a critical component of the rail-infrastructure. It is responsible for activelychanging the route of trains, and must therefore endure higher levels of stress and mechanical fatigue than other elementsof the rail infrastructure. Failures at track switches can result in expensive delays, or even dangerous derailments. In fact,track switches account for 19% of the delays, and have been linked to 110 derailments since 2010. It is thereforeunacceptable that most of the monitoring of critical switches is solely dependent on manual inspections, since they are proneto measurement error and lack of global oversight. The outcome is generally an inaccurate estimation of the State-of-Healthof each switch and re-active – not preventive – maintenance, with financial losses due to delays or additional investment ininfrastructure maintenance. European spending on railway switches is currently over 4B€ (30B€ worldwide). Furthermore,passenger and freight volumes are expected to increase respectively by 34% and 40% by 2030, which means shorterinfrastructure access time for maintenance and monitoring. KONUX has developed the ANDROMEDA system, whichpromises to revolutionize the maintenance procedures for rail infrastructure. The system pulls data from sensors deployedpermanently at the rail switch, which means no more expensive and manual data acquisition. Through self-calibrating smartsensors and machine learning analytics, the result is a holistic overview of the whole rail switch network, with current - andpredicted - State-of-Health for each switch. With a total of 600.000 switches in Europe and 2.510.000 switches
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'Configuration management in the large' (LARGECM) under Fourth Framework.

assistant: **Objectives**

Alenia typical software development activities are complex systems with long operational and maintenance phase. Despite its high maturity level, a weak area is the Configuration Management (CM) supported by basic tools SCCS-like (on VAX-VMS CMS) and make-like (on VAX-VMS MMS). These tools provide only basic Configuration Management mechanisms not adequate for large and critical Air Traffic Control projects. The objective of the experiment is to improve the practice of Configuration Management by moving from a traditional and plain version control of sources (SCCS like) to a comprehensive Configuration Management System covering all process artefacts. This will be performed on a large and varied set of hardware/software platforms, assuring data integrity, inter-operability, improving security and automating the main and most critical process related to configuration management practices.THE EXPERIMENTThe needs for an advanced CM model will be identified and the existing CM tools (CMVC, Continuos, PCMS, etc.) will be appraised to select the tool to de deployed. A Product Model will be defined as resulting from the software development/maintenance process. The CM practices will be formalised, modelled and their enactment will be supported by a process/work-flow engine. Integration and consistency of the Process Model and the Product Model will be of primary concern. Conformance with ISO CM requirements (i.e. ISO 9004-6) is targeted.The identified baseline project (in the maintenance phase) will be migrated from the old practice of source control (SCCS like) to the new one. An expert consultant will support the experiment and a SPICE assessment will verify the achievement of the results.The baseline project of the experiment will be the Plot Buffer (PB) subsystem that execu
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write clear, measurable objectives and define the scope for the project 'PEST RISK ANALYSIS OF PINEWOOD NEMATODE-RELATED BURSAPHELENCHUS SPECIES IN VIEW OF SOUTH EUROPEAN PINE WILTING AND WOOD IMPORTS FROM ASIA' (RISKBURS) under Fourth Framework.

assistant: **Objectives**

The pine wood nematode (Bursaphelenchus xylophilus) is native to North America and has been introduced to East Asia where its spreading caused huge damage and enormous wood losses in Japanese and in Chinese coniferous forests. It can spread from wood, especially when the latter is infested with vector insects. B. xylophilus is a quarantine pest of the EU according to the Directive 77/93/EEC. The occurrence and of pathogenic and apathogenic races and the great morphological and biological similarity with B. mucronatus, which is spread in Eurasia and is primilary of apathogenic nature, make it difficult to characterize populations. Pine wilting of unclear causes has been recently observed in several European countries (Austria, Greece, Italy, Bulgaria, Cyprus), with the role of Bursaphelenchus species involved being unclear. This may involve species closely related with B. xylophilus or B. mucronatus. Interspecific crossability of these species has been proved by experiments and the occurrence of populations modified by transfer of genes is hence possible.The objective is : to develop a Pest Risk Assessment for the EU regarding pinewoodBursaphelenchus species as required for the management of Directive 77/93/EEC in relation to the timber trade with North America.Short description of the project :In order to develop a Pest Risk Assessment for the EU regarding pinewood Bursaphelenchus species, the project will : - assess the occurrence and distribution of Bursaphelenchus nematodes in Europe and in imports.- identify the different species morphologically and by developing molecular biological methods.- develop methods for detection of pathogenicity using molecular biological  techniques and testing of Bursaphelenchus pathogenicity- integration of taxonomic, distribution, hos
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Providing real-time feedback on Internet packet loss and delay' demonstrating excellence, impact and implementation quality for a Sixth Framework call.

assistant: **Abstract**

Today's Internet provides no a priori guarantees about when or if packets will be delivered; this best-effort design has been key to Internet simplicity and scalability. Unfortunately, the Internet also provides no feedback on the fate of transmitted packets. As a result, when a network failure causes packets to get lost or delayed, the sender of the packets has no way of knowing where the failure occurred. This makes it hard for the sender to adapt to the failure (e.g. send its traffic via an alternative path) or hold any administrative entity accountable for it. End-hosts try to address this problem by using probing tools like trace routes. These tools, however, are unreliable, cannot be used to hold ISPs accountable, and are frequently blocked by ISPs for policy or security reasons.This project proposes a solution, in which ISPs are motivated to willingly provide feedback on the loss and delay incurred by traffic within their network. Feedback is collected by monitoring boxes located on inter-ISP links and provided to interested parties. Our proposal attempts to reconcile the academic and industry perspectives on the Internet by developing a solution that is not only technically feasible, but also consistent with the current ISP business model: we enable ISPs to choose the level of feedback they provide, without revealing their internal structure.The proposed mechanism reveals to senders which ISPs are accountable for losing or delaying their packets; as a result, senders are able to evaluate the performance of their ISPs and route their traffic around failure points. Unlike traditional quality-of-service solutions, we do not provide senders with a priori guarantees; we only provide them with a posteriori feedback, which senders can then use to adapt to failures. In
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the novelty, innovation potential and advance beyond the state of the art for 'Developing predictors of the health benefits of exercise for individuals' (META-PREDICT).

assistant: **Innovation**

Physical activity is a powerful lifestyle factor that on average reduces risk for development of diabetes and cardiovascular disease. Nevertheless, we have demonstrated that following supervised endurance exercise training, 20% of subjects show no change in fitness and 30% demonstrate no improvement in insulin sensitivity or worse-still an adverse response. Our concept is that by using molecular profiling of blood/muscle samples we will develop personalised lifestyle intervention tools. Further, revealing the biological basis for a variable metabolic or cardiovascular response to exercise will enable us to propose new targets and biomarkers for drug discovery efforts directly in humans. Using our established OMICS approaches (RNA, DNA and Metabo-) we will generate classifiers that predict the responses to exercise-therapy (fitness and insulin sensitivity). Classifier generation is a statistical strategy for diagnosis or prognosis. Critically, we have a large human tissue biobank, including subjects with insulin-resistance; young to elderly males and females, as well as twins. Our SME partners have significant intellectual property and capacity in the field of bio-prediction, with a proven track-record of collaboration with the team and product development. We will add to the diversity of our biobank by carrying-out an exercise intervention study using a novel time-efficient strategy that we have recently proven to be effective in reducing insulin resistance in sedentary young people and in middle aged obese subjects. A time-efficient protocol is a critical as lack-of-time is a key reason for not maintaining physical activity levels. Finally, we have a novel out-bred rodent model that replicates high and low exercise training responses and we will establish its suitabili
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Synthesis of Spirooxindoles and INdoles pharmaceuticals using Metal-Organic Frameworks' under Horizon 2020.

assistant: **Concept**

SINMOF is a pioneering and structured effort to comprehensively address the introduction of different immobilised isolated catalytic active sites in solid hybrid materials to overcome the metal losses occurring with state-of-the-art homogeneous catalysts employed in the pharmaceutical industry. The convenient use of hybrid metal-organic framework materials (MOFs) respect to traditional state-of-the-art porous solid materials is due to (a) self-deactivation-resistant design of the active sites by (b) ultrastable catalytic site isolation. In the SINMOF project we will (1) design novel multifunctional MOFs as next generation catalysts for the synthesis of pharmaceutically active compounds in an economically and environmentally beneficial way; (2) apply MOF hybrid solids as heterogeneous catalysts to avoid the use of homogeneous metal catalysts in novel synthetic strategies of pharmaceuticals with the indole core and finally (3) derive structure-activity and selectivity relationships at the smallest possible length scales and with the highest possible sensitivities employing fluorescence microscopy. Using a two-stage research methodology, SINMOF will finally provide the most active and stable MOF catalyst for the synthesis of the indole-based neurotransmitter Sumatriptan and the anticancerigen spirooxindole SAR405838. The combined expertise of the fellow and host ensures the best chance for successfully completing the SINMOF objectives in a mutually beneficial manner. On one side, internal collaborations at the host institution will allow the access to state-of-the-art fluorescence microscopy methods, to get new insights into the molecular mechanisms underlying the novel catalytic systems. On the other side, a secondment at a world-leading research center in the homogeneous