RCaz/eu-funding-proposals-sft huggingface dataset:
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Quantitative analysis of the structural controls of faults on induced seismicity magnitude' in the context of a Horizon 2020 call.

assistant: **Objectives**

FINSEIS is a global fellowship addressing the challenge of induced seismicity (IS) caused by human underground activities. The project will explore the original idea that the magnitude of fault-related IS is significantly controlled by the geometry of pre-existing faults, integrating structural geology rather than the different approaches used in previous studies. The project will be based on numerous, best-in-class IS data secured in the Microseismic Industry Consortium (MIC) in University of Alberta (UofA), Canada (Third Country Host) and will integrate advanced knowledge in fracture analysis from the Fault Analysis Group (FAG), University College Dublin (UCD), Ireland (Host).By combining interdisciplinary approaches of structural geology, seismology, statistics and computational science, the project aims to (1) identify the structural controls on the initiation and arrest of induced earthquakes; (2) deliver a unique empirical basis for IS that isolates the effect of fault geometry; (3) generate a model for fault controls on IS and for IS Mw prediction in faulted rocks. Through these objectives, FINSEIS will deliver fundamental scientific outcomes on the links between faults and seismicity and will de-risk strategic geo-energy developments in the European Union.The project will build on the fellow’s previous Post-doc collaborations with FAG and MIC, with the fellow’s research expertise in IS and fault analysis as pre-requisites for the project. During FINSEIS, the fellow will transfer FAG knowledge in structural geology to MIC, and then return knowledge in IS analysis that are strategic to FAG and to Europe. In turn, the project will provide the fellow with a unique profile as a world leader in structural analysis of IS, with international visibility, an excellent rec
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Compose a compelling abstract for 'Innovative solutions for metallic ribs or fittings introduced in a composite box to optimally deal with thermo-mechanical effects' demonstrating excellence, impact and implementation quality for a Horizon 2020 call.

assistant: **Abstract**

The objective of this project is to develop a thorough understanding of the thermo-mechanical behaviour of a hybrid box with composite panels but including metallic ribs or fittings. A building-up approach, from different materials CTE characterization up to the validation of a whole box assembly section, is required to develop and validate the capacity to properly modelize the thermo-mechanical effect in hybrid assemblies. Based on this developed methodology, innovative solutions will be studied for the metallic components of a composite wing-box.


**Keywords:** hybrid, CTE, moisture, models, methods, FEM, FEA, multimaterial structure, composite, titanium, aluminium
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the concept and methodology overview for 'Innocent Deelectronation Chemistry - From the unified redox scale valid in all solvents to innocent deelectronation chemistry in innocent solvents' under Horizon Europe.

assistant: **Concept**

The elementary steps underlying the reversible addition and removal of electrons from matter M –Metals, Molecules or Materials– are the fundament to describe redox chemistry, electrocatalysis and electrochemical energy storage. However, the electrochemical potentials of reaction partners are only comparable within one solvent. This is a consequence of the solvent specific standard states.For this reason, it is a Grand Challenge to establish a Unified Redox Scale to compare electrochemical potentials in all media without extra-thermodynamic assumptions. To achieve this, we use an ‘ideal’ Ionic Liquid Salt Bridge setup to measure the Gibbs transfer energies between different solvents. The measured values, corrected for residual liquid junction potential contributions, will be used to directly connect potentials to the aqueous scale. This unifying solvent-independent scale will allow for knowledge-based comparison and selection of reagents for redox reactions in the next sections.Reagents for deelectronation (removal of an e–) at high potential are scarcely available. Hence, we prepare perhalogenated radical cation salts that act as innocent Deelectronators (iD+) with high unified redox potentials. An iD+ converts a given neutral M to the ‘naked’ cation M+. iD+-salts are straightforwardly accessible and room-temperature stable materials. Conveniently, they are in part weighable in air. Combined with suitable non-reactive, weakly coordinating but polar innocent solvents and robust weakly coordinating anions, reactive cation salts are accessible.Such reversible iD+-mediated redox-processes at high potential are appealing for electrosynthesis and -catalysis. To generate, study and apply these systems, we introduce a generally applicable innocent solvent family compatible with
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Draft an impact statement for 'Development of Global Assays for the diagnosis of thrombotic disorders', explaining its relevance to EU policy priorities under Fourth Framework.

assistant: **Impact**

Thrombotic disorders include some of the most serious clinical conditions in westernised societies, e.g. lung embolism, infarctus, strokes, dementia and acute organ failure. Despite extensive research, there is a lack of a diagnostic laboratory proceedures for these diseases and global (over-all) assays hardly perform at all. As the drug and diagnostics markets related to thrombotic disorders are huge (about 10billion ECU), global assays that explain the disorders and help develop effective drugs have tremendous commercial potential. The basis for the present project is our recent finding that, coagulation induced by endothelial cells is augmented in about 40% of thrombotic patients and clot dissolution and contact factor is impaired in some additional 40%. The project includes novel proprietary rheological technology allowing analysis of whole blood. The project goal is to produce a diagnostic package of reagents and apparatus for performing global assays for the diagnosis of thrombotic disorders.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Biomimetic trick to re-balance Osteblast-Osteoclast loop in osteoporoSis treatment: a Topological and materials driven approach' in the context of a Horizon 2020 call.

assistant: **Objectives**

One out of 5 people in their fifties will experience a bone fracture due to osteoporosis (OP)-induced fragility in their lifetime. The OP socio-economic burden is dramatic and involves tens of millions of people in the EU, with a steadily increasing number due to population ageing. Current treatments entail drug-therapy coupled with a healthy lifestyle but OP fractures need mechanical fixation to rapidly achieve union: the contribution of biomaterial scientists in this field is still far from taking its expected leading role in cutting-edge research. Bone remodelling is a well-coordinated process of bone resorption by osteoclasts followed by the production of new bone by osteoblasts. This process occurs continuously throughout life in a coupling with a positive balance during growth and negative with ageing, which can result in OP. We believe that an architecture driven stimulation of the osteoclast/osteoblast coupling, with an avant-garde focus on osteoclasts activity, is the key to success in treating unbalanced bone remodelling. We aim to manufacture a scaffold that mimics healthy bone features which will establish a new microenvironment favoring a properly stimulated and active population of osteoclasts and osteoblasts, i.e. a well-balanced bone cooperation. After 5 years we will be able to prove the efficacy of this approach. A benchmark will be set up for OP fracture treatment and for the realization of smart bone substitutes that will be able to locally “trick” aged bone cells stimulating them to act as healthy ones. BOOST results will have an unprecedented impact on the scientific research community, opening a new approach to set up smart, biomimetic strategies to treat aged, unbalanced bone tissues and to reduce OP-associated disabilities and financial burdens.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Synthesis and properties of polyhydroxyacid functionalized metathesis polyacetylenes' (SYNTBIOPOL).

assistant: **Concept**

The aim of this project is to synthesize and characterize the biodegradable graft copolymers with a regular non-polar backbone via metathesis polymerisation and the biocompatible, polar side chain via ring opening polymerization. Firstly, the polymerizatio n of various hydroxyalkanes catalyzed by well-defined ruthenium Grubbs catalyst will be investigated to establish the most suitable conditions for the metathesis polymerization of polyhydroxyacid macromonomers with various acetylene end-groups. This preparation method will allow obtaining degradable polymers in a controlled fashion. The graft copolymers will be prepared with different length and composition of the side chain and different length of the backbone chain. Consequently, the chemical and physical properties of the polymer products will be characterized before, during and after in-vitro degradation. The comparison of the properties of biodegradable polymers with polyhydroxyacid side chains and those carrying alcohol functional groups will give information of the nature of the non-polar backbone and polar side chain. This project is multidisciplinary and involves the investigation of the metathesis polymerisation process, synthesis of new biodegradable materials and also their biological studies. The preparation method proposed in this project will give new materials with tailored properties, which would be changed gradually on degradation period. Thus, this feature would lead to use these products in systems where the degradation profile of material s has to be precisely matched to the needs of application, e.g. in environmental and biomedical systems. This project is designed to give the applicant an opportunity to apply her research experiences achieved during her PhD study and Marie Curie Intra-European f
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Write the 'Expected Impact' section for the project 'Deciphering the role of RNA modifications during ribosomal decoding and protein synthesis' (2014-2020), addressing dissemination and exploitation.

assistant: **Impact**

All living cells employ messenger RNAs (mRNA), transfer RNAs (tRNA) and ribosomal RNAs (rRNA) to decode genomic information and synthesize the correct set of proteins at the right sub-cellular localization and at the right time. The attachment of specific chemical groups to individual RNA bases attributes novel chemical properties and strongly influences their functionality. In particular, modifications of the tRNA anticodon and critical regions of rRNAs are primed to influence the translation of individual mRNAs and tune the decoding behavior during ribosomal translation elongation. Individual ribosomes, mRNAs and tRNAs are dynamically decorated with different combinations of RNA modifications depending on the cell type, cellular compartment, metabolic state and environmental conditions. This additional layer of complexity creates specialized translational units and vastly expands the regulatory potential of the strictly conserved and almost invariant core translation machinery. Despite their key role in translation, most modification cascades and the functional interplay of the resulting RNA modifications during ribosomal decoding remain elusive. In the proposed project, we aim (i) to structurally characterize key RNA modification complexes, (ii) to create sets of fully modified RNAs in vitro, (iii) to understand the role of individual rRNA and tRNA modifications during translation elongation and (iv) to provide mechanistic insights into the unfortunate link between patient derived mutations of the underlying pathways and the onset of severe human diseases. In summary, we will extend the recently arising concept of specialized ribosomes by adding unique RNA modifications into the overall scheme. This project will provide deep molecular insights into fundamental proces
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Strongly CORrelated Polaritons In Optoelectronic Nanostructures' (SCORPION).

assistant: **Concept**

Polaritons, part-light part-matter quasi-particles, are formed when photons in a cavity couple strongly to excitons in semiconductors. Polaritons are interacting bosons which can undergo phase transitions driven by light. The hybrid nature of polaritons suggests that both light and matter become strongly correlated near the transition point. Correlated states of light in cavity arrays have been intensely investigated theoretically for over 12 years, but experimental progress has been limited by challenges in the integration of highly nonlinear materials with cavity arrays. Similarly, correlated states of matter (e.g. superconductivity) emerging near polaritonic phase transitions have generated strong theoretical interest in recent years, but their experimental observation has remained elusive. In this project, we will realize strongly correlated light-matter systems in order to solve optimization problems and induce superconductivity with light. We will achieve these goals using a single experimental platform comprising tunable cavities where semiconductors can be easily inserted and light-matter coupling can be tuned in-situ.   In work package 1, we will measure photon correlations in multicavity systems simulating Ising models. We will use these Ising simulators to solve non-deterministic polynomial time (NP)-hard optimization problems, e.g. finding the ground state energy of a 2D Ising model. In work package 2, we will couple  a polariton condensate to a two-dimensional electron system (2DES). We will optically drive this system across the polariton condensation threshold, and  search for signatures of  superconductivity in differential conductance measurements of the 2DES.  We anticipate the results of both work packages to open a new frontier of condensed matter ph
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe how 'Relationships between ecological and chemical status of surface waters' will create measurable scientific, societal and economic impact aligned with Sixth Framework.

assistant: **Impact**

The strategic objective of the REBECCA proposal is to provide relevant scientific support for the implementation of the Water Framework Directive (WFD). The two specific aims of the project are, firstly, to establish links between ecological status of surface waters and physic-chemical quality elements and pressures from different sources, and, secondly, to develop and validate tools that member states can use in the process of classification, in the design of their monitoring programs, and in the design of measures in accordance with the requirements of the WFD. These objectives will be achieved by collating existing knowledge and analysing knowledge gaps, and using this information as a basis for analysing the dose-response relationships between pressures and chemical/biological quality elements based on existing data. Furthermore, REBECCA will explore, develop and improve models and statistical tools, which can be used in assessing the links between the ecological and chemical quality elements; or to assess critical/target loads and other objectives for pressures. These tools will be validated in selected test sites. The results of the project will be disseminated throughout the project lifetime to stakeholders at EU and national levels, particularly to the Working Groups of the Common Implementation Strategy (CIS) for the WFD, and used to develop a Toolbox containing detailed information of the methods, tools and models.
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Describe the specific objectives and expected outcomes for 'Quality platform for open source software' in the context of a Sixth Framework call.

assistant: **Objectives**

QualiPSo aims at making a major contribution to the state of the art and practice of Open Source Software. The goal of the project is to define and implement technologies, procedures and policies to leverage the Open Source Software development current practices to sound and well recognised and established industrial operations".QualiPSo brings together software companies, application solution developers and research institutions and will be driven by the need for having for OSS software the appropriated level of trust which makes OSS development an industrial and wide accepted practice. To reach this goal the QualiPSo project will define, deploy and launch the QualiPSo Competence Centres in Europe (4), Brazil (1) and China (1) all of them making use of the QualiPSo Factory a new generation sorce-forge.Exploitation of results will be achieved through different routes, but with the common theme of partners incorporating these results in current or planned products. Under their founders partners the QualiPSo project will be closely related with important OSS Communities such as QbjectWeb and Morfeo.With the economy moving towards new open models, the potential impact of QualiPSo will be across the entire chain of software system development, proposing an integrated approach along many dimensions:- technically, through a focus on complementary problem areas addressed by strong research teams,- industrially, through application partners from different sectors who share a common vision for the potential of services,- managerially, through the creation of a strong management structure based on an entrepreneurial company,- internationally with partners from different countries coming from different continents,- individually, through strong existing working relationships betwee
system: You are an expert grant writer specializing in European Union research funding proposals. You write compelling, well-structured proposal sections that demonstrate excellence, impact, and implementation quality, using precise EU terminology and following best practices for Horizon Europe, Horizon 2020, and earlier framework programmes.

user: Explain the overall concept, methodology and approach for the project 'Sonio: Deep-Learning for Detection and Diagnostic of Prenatal Malformations' (2021-2027).

assistant: **Concept**

1 child out of 33 is born with a congenital malformation in developed countries, leading to mortality & disability which impact the children, the families & healthcare system. Fetal ultrasound is the standard non invasive examination to screen for malformations, but 50% of malformations are not detected at routine exams as fetal ultrasound is very complex, time-consuming & highly operator-dependent. One needs to acquire the right images, interpret them & combine them with blood or/and genetic tests to get the right diagnosis. We created Sonio, an AI one-stop modular software platform to guide OBGYNS & sonographers during fetal ultrasound. The core is the Clinical Brain, a unique mix between fetal medicine & AI, aware of 1.6k anomalies & 450 syndromes. It can prioritize anomalies to identify the most probable diagnoses based on medical history & observed phenotype. With EIC support, we will fully build image recognition & genomics into our platform to revolutionize prenatal diagnosis.


**Keywords:** Fetal ultrasound,congenital malformation,prenatal diagnosis, Artificial Intelligence,medical imaging,Deep learning,Advanced computing