QuyenAnhDE/medical huggingface dataset:
microsporidiosis
Definition: An opportunistic mycosis that results_in systemic fungal infection in immunocompromised people, has_material_basis_in Microsporidia phylum members.
Synonyms: Infection by Microsporida (disorder)
bovine hemorrhagic syndrome
Definition: A viral infectious disease that results_in infection in cattle, has_material_basis_in Bovine viral diarrhea virus 2, which is transmitted_by ingestion of infected food, or transmitted_by nasal secretions. The infection has_symptom low grade fever, has_symptom bloody diarrhea, and has_symptom bleeding in the eyes.
Pestivirus infectious disease
Definition: A viral infectious disease that results_in infection in mammals, has_material_basis_in Pestivirus, which is transmitted_by contact with nasal secretions of an infected animal. The infection has_symptom diarrhea, has_symptom respiratory problems, and has_symptom bleeding disorder.
penis basal cell carcinoma
Synonyms: basal cell carcinoma of the penis RELATED []
scrotum basal cell carcinoma
Synonyms: basal cell carcinoma of the scrotum RELATED []
infundibulocystic basal cell carcinoma
Synonyms: skin infundibulocystic basal cell carcinoma
nodular basal cell carcinoma
Synonyms: skin solid (nodular) Basal cell carcinoma
metatypical basal cell carcinoma
Synonyms: skin Metatypical carcinoma
pigmented basal cell carcinoma
Synonyms: skin pigmented basal cell carcinoma
anal margin basal cell carcinoma
Synonyms: Basal cell carcinoma of Perianal skin
anal margin carcinoma
Definition: An anal carcinoma that has_material_basis_in abnormally proliferating cells derives_from epithelial cells and is located_in the anal margin (where the canal meets the outside skin at the anus).
Synonyms: Perianal skin carcinoma
complications of pregnancy, childbirth and the puerperium
sebaceous basal cell carcinoma
Synonyms: skin basosebaceous basal cell carcinoma
external ear basal cell carcinoma
Synonyms: Basal cell carcinoma of the External ear
external ear carcinoma
Definition: An external ear cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.
Synonyms: carcinoma of the External ear
micronodular basal cell carcinoma
Synonyms: skin micronodular basal cell carcinoma
gynatresia
adamantinoid basal cell epithelioma
Synonyms: skin adamantinoid basal cell epithelioma
fibroepithelial basal cell carcinoma
Synonyms: Pinkus tumor
morpheaform basal cell carcinoma
Synonyms: Morphea-type (Sclerosing) Basal cell carcinoma
clear cell basal cell carcinoma
Synonyms: skin clear cell basal cell carcinoma
adenoid basal cell carcinoma
Synonyms: skin adenoid basal cell carcinoma
follicular basal cell carcinoma
Synonyms: follicular (pilar) basal cell carcinoma
scimitar syndrome
Synonyms: total anomalous pulmonary venous return
respiratory system abnormality
infiltrative basal cell carcinoma
Synonyms: skin infiltrating basal cell carcinoma
superficial basal cell carcinoma
Synonyms: Superficial multicentric basal-cell carcinoma
vulva basal cell carcinoma
Synonyms: Basal cell carcinoma of Vulva
cystic basal cell carcinoma
Synonyms: skin cystic basal cell carcinoma
sarcomatoid basal cell carcinoma
Synonyms: skin sarcomatoid basal cell carcinoma
signet ring basal cell carcinoma
Synonyms: skin signet ring cell basal cell carcinoma
bone giant cell tumor
Definition: A giant cell tumor and bone cancer and bone tissue neoplasm that results_in the presence of multinucleated giant cells (osteoclast-like cell).
Synonyms: osteoclastoma RELATED []
radiculopathy
Synonyms: nerve root disorder, NOS
polyradiculopathy
Synonyms: Polyradiculopathy (disorder)
polyradiculoneuropathy
Synonyms: Polyradiculoneuropathy (disorder)
myofascial pain syndrome
smooth muscle tumor
Synonyms: Smooth muscle tumour of uncertain malignant potential
epidermolysis bullosa acquisita
Synonyms: acquired epidermolysis bullosa (disorder)
visna
Definition: A viral infectious disease that results_in infection located_in brain in sheep and goats, has_material_basis_in Visna/Maedi virus , which is transmitted_by droplet spread of oronasal secretion, and transmitted_by ingestion of contaminated water, milk or colostrum. The infection has_symptom hindlimb weakness, has_symptom head tilt, has_symptom ataxia, has_symptom incoordination, has_symptom muscle tremors, has_symptom paresis, and has_symptom paraplegia.
Synonyms: Ovine encephalomyelitis
non-gestational choriocarcinoma
large cell acanthoma
pilar sheath acanthoma
Synonyms: Pilar sheath acanthoma (disorder)
epidermolytic acanthoma
acantholytic acanthoma
Synonyms: Acantholytic acanthoma
Ebola hemorrhagic fever
Definition: A viral infectious disease that is a hemorrhagic fever, has_material_basis_in Zaire ebolavirus, has_material_basis_in Sudan ebolavirus, has_material_basis_in Cote d'Ivoire ebolavirus, or has_material_basis_in Bundibugyo ebolavirus, which are transmitted_by contact with the body fluids of an infected animal or person, transmitted_by contaminated fomites, or transmitted_by infected medical equipment. The infection has_symptom fever, has_symptom headache, has_symptom joint pain, has_symptom muscle aches, has_symptom sore throat, has_symptom weakness, has_symptom diarrhea, has_symptom vomiting, has_symptom stomach pain, has_symptom rash, has_symptom red eyes, has_symptom hiccups, and has_symptom internal and external bleeding.
Synonyms: Ebola virus disease
Filoviridae infectious disease
Definition: A Mononegavirales infectious disease that results_in infection in animals and humans, has_material_basis_in Filoviridae viruses.
Marburg hemorrhagic fever
Definition: A viral infectious disease that is a hemorrhagic fever, has_material_basis_in Marburgvirus, which is transmitted_by contact with the body fluids of an infected person. The infection has_symptom fever, has_symptom chills, has_symptom headache, has_symptom myalgia, has_symptom maculopapular rash on the trunk, has_symptom nausea, has_symptom vomiting, has_symptom chest pain, has_symptom sore throat, has_symptom abdominal pain, has_symptom diarrhea, and has_symptom bleeding.
Synonyms: Marburg virus disease
Erdheim-Chester disease
Intraventricular hemorrhage from any perinatal cause
non-langerhans-cell histiocytosis
Synonyms: Non-Langerhans cell histiocytosis
burning mouth syndrome
Synonyms: Stomatopyrosis
familial hypophosphatemia
Synonyms: Hypophosphatemia, familial
parovarian cyst
Synonyms: Embryonic fimbrial cyst
splenic manifestation of prolymphocytic leukemia
tinea favosa
Definition: A tinea capitis that results_in fungal infection located_in scalp, located_in glabrous skin or located_in nail, has_material_basis_in Ascomycota fungi that belong to a group called dermatophytes and results_in_formation_of scutula, yellowish cup-shaped crusts of dense masses of mycelium and epithelial debris, which develop at the surface of a hair follicle with the shaft in the center of the raised lesion. Removal of these crusts reveals an oozing, moist, red base. Later, atrophy of the skin occurs leaving a cicatricial alopecia and scarring.
Synonyms: Tinea favosa (disorder)
tinea capitis
Definition: A dermatophytosis that results_in contagious fungal infection located_in scalp, located_in hair of head, located_in eyebrow or located_in eyelash, has_material_basis_in Ascomycota fungi that belong to a group called dermatophytes and has_symptom itching of the scalp, has_symptom pus filled lesions on the scalp, and has_symptom patches of hair loss, sometimes with a 'black dot' pattern.
Synonyms: Trichophyton rubrum tinea capitis
anterior mediastinum cancer
variegate porphyria
Synonyms: Variegate porphyria (disorder)
lymphocele
Synonyms: Lymphocyst (morphologic abnormality)
complications occurring mainly in the course of labor and delivery
Synonyms: Rupture of uterus before onset of labor, with delivery
malignant neoplasm of thymus, heart and mediastinum
bovine anaplasmosis
Synonyms: Anaplasmosis (disorder)
primary Anaplasmataceae infectious disease
ciliary body cancer
Synonyms: tumor of the Ciliary body
ciliary body disease
regressing malignant melanoma
Synonyms: regressing melanoma
experimental melanoma
Synonyms: Experimental malignant melanoma
metastatic melanoma
amelanotic melanoma
Synonyms: Amelanotic melanoma (morphologic abnormality)
posterior mediastinum cancer
epithelioid cell melanoma
Synonyms: epithelioid melanoma
cervical cancer
Definition: A female reproductive organ cancer that is located_in the cervix.
Synonyms: uterine cervical neoplasm
malignant breast melanoma
Synonyms: malignant melanoma of breast (disorder)
apparent mineralocorticoid excess syndrome
Synonyms: syndrome of apparent mineralocorticoid excess (disorder)
brain hypoxia-Ischemia
myasthenia gravis
stomach diverticulosis
Schnitzler syndrome
Synonyms: Schnitzler syndrome (disorder)
intracranial embolism
Synonyms: Cerebral embolism with cerebral infarction
silo filler's disease
Synonyms: Silo-fillers' disease
agricultural workers' disease
milk allergy
Definition: A food allergy that results in adverse immune reaction to one or more of the proteins in cow's milk and/or the milk of other animals, which are normally harmless to the non-allergic individual.
Synonyms: milk allergic reaction
egg allergy
Definition: A food allergy that is an allergy or hypersensitivity to dietary substances from the yolk or whites of eggs, causing an overreaction of the immune system which may lead to severe physical symptoms. [ls:IEDB, url:http://en.wikipedia.org/wiki/Allergy#Foods]
Synonyms: Allergy to eggs (disorder)
peanut allergy
Definition: A food allergy that is an allergy or hypersensitivity to dietary substances from peanuts causing an overreaction of the immune system which in a small percentage of people may lead to severe physical symptoms. [ls:IEDB, url:http://en.wikipedia.org/wiki/Allergy#Foods]
Synonyms: peanut allergic reaction
nut allergy
Synonyms: nut allergic reaction
autoimmune disease of the nervous system
Synonyms: autoimmune nervous system disorder RELATED [CSP2005:1560-5548]
conventional alveolar rhabdomyosarcoma
solid alveolar rhabdomyosarcoma
orbit alveolar rhabdomyosarcoma
Synonyms: Alveolar Rhabdomyosarcoma of the orbit
papillary squamous carcinoma
Definition: A squamous cell carcinoma that has papillae, which are characterized either by narrow fibrovascular cores that superficially resemble papillary carcinoma of the urinary tract or by broad cores that contain edematous fibrous stroma with prominent capillaries and stromal inflammation.
Synonyms: papillary epidermoid carcinoma
myofibroma
Synonyms: Myofibroma (morphologic abnormality)
recurrent peripheral primitive neuroectodermal tumor
bone peripheral neuroepithelioma
Synonyms: osseous peripheral Neuroepithelioma
soft tissue peripheral neuroepithelioma
Synonyms: peripheral Neuroectodermal tumor of soft tissues
neuromuscular junction disease
Definition: A neuromuscular disease that is characterized by the disfunction of conduction through the neuromuscular junction.
Henipavirus infectious disease
Definition: A Paramyxoviridae infectious disease that results_in infection in domestic animals and humans, has_material_basis_in Henipavirus, which is transmitted_by direct contact with the urine, feces, and nasal secretions of an infected animal.
reticulohistiocytic granuloma
Synonyms: Solitary reticulohistiocytoma
granulomatous dermatitis
pustulosis of palm and sole
Synonyms: Pustular psoriasis of the palms and/or soles
acneiform dermatitis
neuromuscular disease
Definition: A neuropathy that affect the nerves that control the voluntary muscles.
dermatosis papulosa nigra
Synonyms: Dermatosis papulosa nigra (morphologic abnormality)
cervical glandular tumor
occupational dermatitis
Synonyms: Occupational eczema (disorder) [Ambiguous]
spongiotic dermatitis
Synonyms: Spongiotic dermatitis (disorder)
phototoxic dermatitis
Synonyms: Phototoxic dermatitis (disorder)
folliculitis
Synonyms: (Folliculitis) or (seborrhea capitis)
contact dermatitis due to arnica
Synonyms: Dermatitis due to arnica
hepatitis E
Definition: A viral infectious disease that results_in inflammation located_in liver, has_material_basis_in Hepatitis E virus, which is transmitted_by ingestion of contaminated food. The infection has_symptom fever, has_symptom fatigue, has_symptom loss of appetite, has_symptom nausea, has_symptom vomiting, has_symptom abdominal pain, has_symptom clay-colored bowel movements, has_symptom dark urine, has_symptom joint pain, and has_symptom jaundice.
Astroviridae infectious disease
Definition: A (+)ssRNA virus infectious disease that results_in infection in animals and humans, has_material_basis_in Astroviridae viruses.
cervix melanoma
fibrous histiocytoma
Synonyms: Fibroxanthoma NOS (morphologic abnormality)
cutaneous fibrous histiocytoma
Synonyms: Sclerosing angioma of skin
benign deep fibrous histiocytoma
malignant adenofibroma
sea-blue histiocyte syndrome
Synonyms: Sea-blue histiocyte syndrome (disorder)
juvenile xanthogranuloma
Synonyms: Xanthoma neviforme
lipogranuloma
Synonyms: Xanthogranuloma (disorder)
dyslexia
Definition: A reading disorder resulting from a developmental reading disability involving the inability to process graphic symbols resulting in impairment of reading ability.
somatostatinoma
Synonyms: Somatostatinoma (disorder)
pancreatic somatostatinoma
Synonyms: pancreatic Somatostatin cell tumor
pancreatic delta cell neoplasm
Synonyms: pancreatic Delta cell tumor
small intestine neuroendocrine neoplasm
Synonyms: small Intestine neuroendocrine tumor
cavernous sinus meningioma
Synonyms: meningioma of the Cavernous sinus
anterior cranial fossa meningioma
Synonyms: meningioma of the Anterior Fossa
skull base meningioma
Synonyms: meningioma of the Skull Base
central nervous system germinoma
Synonyms: germinoma of CNS
central nervous system germ cell tumor
Synonyms: germ cell tumor of the CNS
seminoma
Definition: A germinoma that has_material_basis_in cells that make sperm and eggs.
Synonyms: Seminoma, Pure
dysgerminoma
Definition: A germ cell cancer that derives_from cells that give rise to egg cells.
cervical alveolar soft part sarcoma
Definition: An alveolar soft part sarcoma and cervical soft tissue tumor and malignant neoplasm of cervix uteri that is located_in the cervix.
cervical soft tissue tumor
arachnoid cyst
Synonyms: Leptomeningeal Cyst
central nervous system cyst
Synonyms: Cyst of the CNS
cystoid macular edema
macular degeneration
Definition: A retinal degeneration characterized by gradual deterioration of light-sensing cells in the tissues at the back of the eye; symptoms include vision loss.
Synonyms: Macular degeneration of retina
macular retinal edema
Synonyms: macular edema
Bartter disease
Synonyms: Bartter's syndrome
renal cell carcinoma
Definition: A renal carcinoma that has_material_basis_in the lining of the proximal convoluted renal tubule of the kidney.
Synonyms: RCC
renal carcinoma
Definition: A kidney cancer that derives_from the lining of the proximal convoluted tubule (the very small tubes in the kidney that filter the blood and remove waste products).
Synonyms: kidney carcinoma
recurrent renal cell carcinoma
Synonyms: Relapsed Renal cell carcinoma
childhood kidney cell carcinoma
Synonyms: pediatric renal cell carcinoma
hereditary renal cell carcinoma
hyperaldosteronism
Definition: An adrenal gland hyperfunction disease that results in the overproduction of aldosterone by the adrenal glands.
multilocular clear cell renal cell carcinoma
Synonyms: renal cystadenocarcinoma
collecting duct carcinoma
Definition: Collecting duct carcinoma is a renal cell carcinoma described as a rare and aggressive type of renal cell carcinoma. The cancerous cells form irregular tubes inside the tumor. Collecting duct carcinoma is more common among young people and unfortunately is diagnosed in most cases when the cancer has metastasized (spread inside the body). [URL:http://www.omnimedicalsearch.com/conditions-disease/renal-cell-carcinoma-overview-types.html]
Synonyms: renal Medullary carcinoma
papillary renal cell carcinoma
Definition: A renal cell carcinoma that is characterized by the development of multiple, bilateral papillary renal tumors.
Synonyms: sporadic papillary renal cell carcinoma
renal clear cell carcinoma
Definition: A renal cell carcinoma that has_material_basis_in cells that appear very pale or clear when examined under microscope.
Synonyms: conventional renal cell carcinoma
clear cell adenocarcinoma
Definition: An adenocarcinoma that derives_from epithelial cells which have clear cytoplasm.
Synonyms: Wolffian duct neoplasm
renal tubular transport disease
Synonyms: inborn renal tubular transport disorder
chromophobe adenocarcinoma
Definition: A renal cell carcinoma that has_material_basis_in chromophobe cell that appear pale when viewed under microscope, but that are larger and display different features than clear cells.
Synonyms: renal cell carcinoma, chromophobe cell
mucinous tubular and spindle renal cell carcinoma
sarcomatoid renal cell carcinoma
Synonyms: renal cell carcinoma, spindle cell
drug-Induced dyskinesia
Synonyms: Drug-induced dyskinesia (disorder)
pseudohypoaldosteronism
facial neoplasm
Synonyms: neoplasm of face (disorder)
achondroplasia
Definition: An osteochondrodysplasia that results_in dwarfism which has_material_basis_in abnormal ossification of cartilage in located_in long bone.
Synonyms: osteosclerosis congenita
allergic rhinitis
Definition: A rhinitis that is an allergic inflammation and irritation of the nasal airways involving sneezing, runny nose, nasal congestion, itching and tearing of the eyes caused by exposure to an allergen such as pollen, dust, mold, animal dander and droppings of cockroaches or house dust mites. [ls:IEDB, url:http://en.wikipedia.org/wiki/Allergic_rhinitis, url:http://en.wikipedia.org/wiki/Rhinitis, url:http://www.aaaai.org/patients/resources/easy_reader/rhinitis.pdf, url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=allergic%20rhinitis]
Synonyms: seasonal allergic rhinitis
rhinitis
Definition: A upper respiratory infectious disease which involves irritation and inflammation of the mucous membrane of the nose due to viruses, bacteria or irritants. The inflammation results in generation of excessive amounts of mucus leading to runny nose, as well as nasal congestion and post-nasal drip.
Synonyms: runny nose RELATED []
malignant biphasic mesothelioma
Synonyms: mixed Mesothelioma
sarcomatoid mesothelioma
Synonyms: spindled mesothelioma
malignant epithelial mesothelioma
Synonyms: epithelioid mesothelioma, malignant (morphologic abnormality)
head neoplasm
Synonyms: neoplasm of the head
malignant peritoneal solitary fibrous tumor
Synonyms: Pleural and peritoneal Solitary fibrous tumor
persian gulf syndrome
Definition: A syndrome affecting returning military veterans and civilian workers of the Gulf War.
Synonyms: Gulf war syndrome (disorder)
avian influenza
Definition: An influenza that results_in infection located_in respiratory tract of humans, domestic and wild birds, has_material_basis_in Influenza A virus, which is transmitted_by contact with infected poultry. Five strains of avian influenza A viruses (H5N1, H7N3, H7N2, H7N7 and H9N2) are known to cause human infections. The infection has_symptom fever, has_symptom cough, has_symptom sore throat, has_symptom muscle aches, has_symptom nausea, has_symptom diarrhea, has_symptom vomiting, has_symptom neurologic changes, has_symptom pneumonia, and has_symptom acute respiratory distress.
Synonyms: bird flu
Orthomyxoviridae infectious disease
Definition: A (-)ssRNA virus infectious disease that results_in infection in animals and humans, has_material_basis_in Orthomyxoviridae family viruses, which are transmitted_by droplet spread of respiratory secretions or transmitted_by contaminated fomites.
Synonyms: Orthomyxoviridae disease
metastatic malignant neoplasm to the cervix
Synonyms: secondary malignant neoplasm of uterine cervix (disorder)
child nutrition disorder
myotonic disease
Definition: A muscular dystrophy that is characterized by progressive muscle wasting and weakness.
hypokalemia
Synonyms: potassium deficiency disorder  RELATED []
orofaciodigital syndrome
Definition: A genetic disease that is characterized by malformations of the face, oral cavity, and digits with polycystic kidney disease and variable involvement of the central nervous system and has_material_basis_in X-linked inheritance of an OFD gene.
relapsed angiosarcoma
Synonyms: relapsed hemangiosarcoma
central nervous system angiosarcoma
Definition: A central nervous system sarcoma that is located_in the inner lining of blood vessels.
Synonyms: hemangiosarcoma of the CNS
pediatric angiosarcoma
Definition: An angiosarcoma that affects children.
Synonyms: pediatric hemangiosarcoma
angiosarcoma associated with lymphedema
aorta angiosarcoma
Definition: An angiosarcoma that is located_in the aorta.
Synonyms: Aortic hemangiosarcoma
breast angiosarcoma
Definition: An angiosarcoma and sarcoma of breast and vascular neoplasm of breast that is located_in the cells that line the blood vessels within the breast or underarm area.
Synonyms: hemangiosarcoma of the breast
conventional angiosarcoma
gallbladder angiosarcoma
Definition: An angiosarcoma and gallbladder sarcoma that is located_in the gallbladder.
Synonyms: hemangiosarcoma of gallbladder
thyroid angiosarcoma
Definition: A thyroid sarcoma and angiosarcoma that results_in a high prevalence of iodine-deficient goiter.
Synonyms: hemangiosarcoma of the Thyroid
thyroid sarcoma
Definition: A thyroid cancer that is located_in the supporting cells of the thyroid.
Synonyms: sarcoma of the Thyroid gland
skin angiosarcoma
Definition: An angiosarcoma and hemangioma of skin and malignant skin vascular tumor and sarcoma of skin that is located_in the skin and results_in an enlarged bruise (a blue-black nodule) and an unhealed ulceration.
Synonyms: hemangiosarcoma of the skin
pleomorphic adenoma
Definition: A gastrointestinal benign neoplasm that is a located_in the salivary glands.
Synonyms: Pleomorphic adenoma (morphologic abnormality)
cervical endometrial stromal sarcoma
Synonyms: endometrial stromal sarcoma of the cervix
cervix endometrial stromal tumor
superior vena cava angiosarcoma
Synonyms: angiosarcoma of the Superior Vena Cava
prostate angiosarcoma
Definition: An angiosarcoma and sarcoma of prostate that is located_in the prostate.
Synonyms: Prostatic hemangiosarcoma
mediastinum angiosarcoma
Definition: An angiosarcoma and sarcoma of the mediastinum that is located_in the mediastinum.
Synonyms: hemangiosarcoma of mediastinum
ovarian angiosarcoma
Synonyms: hemangiosarcoma of Ovary
mucoepidermoid carcinoma
Definition: A salivary gland carcinoma that is characterized by squamous cells, mucus-secreting cells, and intermediate cells.
Synonyms: Mucoepidermoid carcinoma (morphologic abnormality)
Hallermann-Streiff syndrome
Definition: A syndrome that affects growth, cranial development, hair growth and dental development.
Synonyms: Hallermann's syndrome
hypotrichosis
Definition: A hair disease that is characterized by sparse hair on the scalp resulting from abnormal hair follicle development and has_material_basis in mutations in proteins involved in hair growth, division or proliferation of cells within hair follicles.
labyrinthine disease
dysgraphia
Definition: A writing disorder that involves a deficiency in the ability to write where the writing is distorted or incorrect, spelling difficulty, poor handwriting or trouble putting thoughts on paper.
nominal aphasia
Definition: An agnosia that involves a severe problem with recalling words or names.
Synonyms: Anomic aphasia (finding)
basophil adenoma
Synonyms: Pituitary gland Basophilic adenoma
retrograde amnesia
Definition: An amnestic disorder that involves a loss of one's pre-existing memories to conscious recollection.
mesenchymal chondrosarcoma
pediatric mesenchymal chondrosarcoma
adult mesenchymal chondrosarcoma
Definition: An adult sarcoma of soft tissue and mesenchymal chondrosarcoma that is located_in the cartilage.
extraskeletal mesenchymal chondrosarcoma
Synonyms: mesenchymal extraosseous chondrosarcoma
extraosseous chondrosarcoma
Definition: A chondrosarcoma that is located_in exclusively soft tissue.
anal gland neoplasm
anus neoplasm
Synonyms: neoplasm of anus (disorder)
large cell carcinoma
Definition: A carcinoma that is composed of large, monotonous rounded or overtly polygonal-shaped cells with abundant cytoplasm.