Blow is a 2001 American biographical crime film about the American cocaine smuggler George Jung, directed by Ted Demme.
 David McKenna and Nick Cassavetes adapted Bruce Porter's 1993 book "Blow: How a Small Town Boy Made $100 Million with the Medellín Cocaine Cartel and Lost It All" for the screenplay.
 It is based on the real-life stories of George Jung, Pablo Escobar, Carlos Lehder Rivas (portrayed in the film as Diego Delgado), and the Medellín Cartel.
 The film's title comes from a slang term for cocaine.
John Q. is a 2002 American crime film starring Denzel Washington and directed by Nick Cassavetes.
 The film tells the story of John Quincy Archibald (Denzel Washington), a father and husband whose son is diagnosed with an enlarged heart and finds out he is unable to receive a transplant because HMO insurance will not cover it, before he decides to hold up the hospital and force them to do it.
Sins of the Night is a 1993 American thriller and crime film directed by Gregory Dark and produced by Andrew W. Garroni.
 This film has bean music composed by Ashley Irwin.
The film starring Nick Cassavetes, Deborah Shelton, Miles O'Keeffe and Richard Roundtree in the lead roles.
Yellow is a 2012 American drama film directed by Nick Cassavetes and written by Nick Cassavetes and Heather Wahlquist.
 The film stars Riley Keough, Sienna Miller, David Morse, Ray Liotta, Melanie Griffith and Lucy Punch.
 The film was awarded "Best Film" at the Catalina Film Festival on September 22, 2013.
She's So Lovely is a 1997 film directed by Nick Cassavetes, written by John Cassavetes.
 At the time of its release, it received special attention because, eight years after his death, it was the first (and still only) posthumous film to feature previously unreleased material from John Cassavetes.
Amber Laura Heard (born April 22, 1986) is an American actress.
 She made her film debut in 2004 in the sports drama "Friday Night Lights".
 After small roles in "North Country" and "Alpha Dog", Heard played her first leading role in "All the Boys Love Mandy Lane" (2006) and appeared in The CW television show "Hidden Palms" (2007).
American entertainer Jennifer Lopez has appeared in many motion pictures and television programs.
 She is one of the highest paid actresses in Hollywood and is the highest paid actress of Latin descent, making up to US$15 million per film role.
 She is also the richest actress in Hollywood, with an estimated net worth of $320 million (as of 2014).
 Lopez made her acting debut at age 16 with a small role in the 1986 film "My Little Girl".
 From there, she received her first high-profile job in 1991 as a Fly Girl dancer on the television comedy program "In Living Color".
 Following her departure from the show in 1993, Lopez made several guest appearances in the television series "South Central", appeared in the made-for-television movie "Lost in the Wild" (1993) and starred as Melinda Lopez in the television series "Second Chances" (1993) and its spin-off "Hotel Malibu" (1994).
 "Second Chances" and "Hotel Malibu" ran for only a brief period, receiving negative reviews.
 Lopez's first major film role came in the 1995 motion picture "Money Train", alongside Wesley Snipes and Woody Harrelson.
 The film faced negative reviews and is considered to be a box office bomb.
 Her next two film roles in "Jack" (1996) and "Blood and Wine" (1997) were received similarly; however, critics were divided by the latter.
 Lopez received her first leading role in the Selena biopic of the same name in 1997.
 The film was a commercial and critical success and is often cited by critics as her breakout role.
 Later that year, Lopez starred as Terri Flores in the film "Anaconda", which garnered negative reviews by critics despite being a box office success.
 In 1998, Lopez starred alongside George Clooney in the crime film "Out of Sight" (1998).
 The film met with positive reviews and was a box office success.
 In the same year, she also lent her voice to the animated film "Antz".
The Notebook is a 2004 American romantic drama film directed by Nick Cassavetes and based on the 1996 novel of the same name by Nicholas Sparks.
 The film stars Ryan Gosling and Rachel McAdams as a young couple who fall in love in the 1940s.
 Their story is narrated from the present day by an elderly man (portrayed by James Garner) telling the tale to a fellow nursing home resident (played by Gena Rowlands, who is Cassavetes's mother).
The Other Woman is a 2014 American comedy film, directed by Nick Cassavetes and written by Melissa Stack.
 The film stars Cameron Diaz, Leslie Mann and Kate Upton, with Nikolaj Coster-Waldau, Nicki Minaj and Taylor Kinney in supporting roles.
 The film follows three womenCarly (Diaz), Kate (Mann), and Amber (Upton)who are all romantically involved with the same man, Mark (Coster-Waldau).
 After finding out about each other, the trio decide to take revenge on Mark.
Alpha Dog is a 2006 American crime drama film written and directed by Nick Cassavetes, first screened at the Sundance Film Festival on January 27, 2006, with a wide release the following year on January 12, 2007.
 Starring Emile Hirsch, Justin Timberlake, Ben Foster, Shawn Hatosy, Anton Yelchin, Olivia Wilde, Amanda Seyfried with Harry Dean Stanton, Sharon Stone, and Bruce Willis, the film is based on the true story of the kidnapping and murder of Nicholas Markowitz in 2000.

Question: In what film was the first leading role for Amber Heard, who had a small role in Nick Cassavetes' 2006 crime film?
Answer: All the Boys Love Mandy Lane