Fatal Instinct is a 2014 American action film, written, directed and produced by Luciano Saber, starring Ivan Sergei, Masiela Lusha, Richard Burgi, Drew Fuller, Krista Allen, Peter Dobson, and Anne Winters.
 The film premiered in the United States on June 3, 2014, airing on the Showtime network.
Constance Marie Lopez (born September 9, 1965) known professionally as Constance Marie, is an American actress.
 She is known for her role as Angie Lopez on "George Lopez" (2002–2007) and her role as Marcela Quintanilla (mother of Selena) in the 1997 film "Selena".
 She portrayed Regina Vasquez on the ABC Family/Freeform drama "Switched at Birth" (2011–2017).
Saint George is an American television sitcom created by George Lopez, David McFadzean, and Matt Williams, which originally aired on FX from March 6, 2014, to May 8, 2014.
 It is Lopez's first starring role in a scripted series since his ABC show "George Lopez".
George Lopez is an American television sitcom created by comedian George Lopez, Bruce Helford and Robert Borden, which originally aired for six seasons, 120 episodes, on ABC from March 27, 2002, to May 8, 2007.
 It is currently in syndication.
 "George Lopez" stars the titular comedian George Lopez, who plays a fictionalized version of himself and revolves around his life at work and raising his family at home.
 The series was produced by Fortis Films and Mohawk Productions in association with Warner Bros.
 Television.
 The executive producers consisted of George Lopez, Bruce Helford, Deborah Oppenheimer and Sandra Bullock.
 On September 2, 2016, George Lopez announced through his Instagram that there are talks to bringing the show back on the air, but nothing has been announced.
Masiela Lusha ( ; born October 23, 1985) is an American actress, author, producer and humanitarian.
 Lusha gained worldwide recognition for playing her first major role as Carmen Consuelo Lopez on the globally syndicated ABC sitcom "George Lopez", a role which earned her two consecutive Young Artist Awards for Leading Young Actress in a Comedy or Drama.
 After transitioning into film, she had her breakout role in Sony Picture's "".
 Lusha also starred alongside David Hasselhoff and Ian Ziering in SyFy's television movie "".
Laura Johnson (born August 1, 1957) is an American actress, known for playing Terry Hartford in the primetime soap opera "Falcon Crest" from 1983 to 1986.
 She had a supporting role in the independent film "Beyond Reason" in 1977 and also appeared in "Opening Night" (1977), and "Fatal Instinct" (1992).
 On television she also starred in two short-lived series: "Heartbeat" and "Born Free".
Aimee Garcia (born November 28, 1978) is an American actress.
 She is known for her television roles as Veronica Palmero on the ABC sitcom "George Lopez", Yvonne Sanchez on the CBS period drama "Vegas", and Jamie Batista on the Showtime drama "Dexter".
Aurabela "Belita" Moreno (born November 1, 1949) is an American actress best known for her roles as Benita "Benny" Lopez on the ABC sitcom "George Lopez" and Edwina Twinkacetti/Lydia Markham on "Perfect Strangers".
George Lopez (born April 23, 1961) is an American comedian and actor.
 He is known for starring in his self-produced ABC sitcom "George Lopez".
 His stand-up comedy examines race and ethnic relations, including Mexican American culture.
 Lopez has received several honors for his work and contributions to the Latino community, including the 2003 Imagen Vision Award, the 2003 Latino Spirit Award for Excellence in Television and the National Hispanic Media Coalition Impact Award.
 He was also named one of "The Top 25 Hispanics in America" by Time magazine in 2005.
American entertainer Jennifer Lopez has appeared in many motion pictures and television programs.
 She is one of the highest paid actresses in Hollywood and is the highest paid actress of Latin descent, making up to US$15 million per film role.
 She is also the richest actress in Hollywood, with an estimated net worth of $320 million (as of 2014).
 Lopez made her acting debut at age 16 with a small role in the 1986 film "My Little Girl".
 From there, she received her first high-profile job in 1991 as a Fly Girl dancer on the television comedy program "In Living Color".
 Following her departure from the show in 1993, Lopez made several guest appearances in the television series "South Central", appeared in the made-for-television movie "Lost in the Wild" (1993) and starred as Melinda Lopez in the television series "Second Chances" (1993) and its spin-off "Hotel Malibu" (1994).
 "Second Chances" and "Hotel Malibu" ran for only a brief period, receiving negative reviews.
 Lopez's first major film role came in the 1995 motion picture "Money Train", alongside Wesley Snipes and Woody Harrelson.
 The film faced negative reviews and is considered to be a box office bomb.
 Her next two film roles in "Jack" (1996) and "Blood and Wine" (1997) were received similarly; however, critics were divided by the latter.
 Lopez received her first leading role in the Selena biopic of the same name in 1997.
 The film was a commercial and critical success and is often cited by critics as her breakout role.
 Later that year, Lopez starred as Terri Flores in the film "Anaconda", which garnered negative reviews by critics despite being a box office success.
 In 1998, Lopez starred alongside George Clooney in the crime film "Out of Sight" (1998).
 The film met with positive reviews and was a box office success.
 In the same year, she also lent her voice to the animated film "Antz".

Question: What Fatal Instinct star had her first major role on the ABC sitcom "George Lopez"?
Answer: Masiela Lusha