Miletus ( ; Ancient Greek: Μί̄λητος  "Mīlētos" ; Hittite transcription "Millawanda" or "Milawata" (exonyms); Latin: "Miletus" ; Turkish: "Milet" ) was an ancient Greek city on the western coast of Anatolia, near the mouth of the Maeander River in ancient Caria.
 Its ruins are located near the modern village of Balat in Aydın Province, Turkey.
 Before the Persian invasion in the middle of the 6th century BC, Miletus was considered the greatest and wealthiest of Greek cities.
 In other sources however it is mentioned that the city was much more modest up until the Peloponnesian War (431–404 BC), when, for example, the city state of Samos on the island of Samos opposite Miletus was considered a larger and more important city and harbor.
 Miletus' greatest wealth and splendor was reached during the Hellenistic era (323–30 BC) and later Roman times.
Oesyme or Oisyme (Attic Greek: Οίσύμη, Doric Greek: Οίσύμα, Homeric Greek: Αίσύμη) was an ancient Greek polis located in Thrace and later in Macedonia.
 It was within the region of Edonis between the river Strymon and the river Nestos.
 It was founded by colonists from Thasos perhaps at 650 BC.It was later renamed (Ancient Greek: Ημαθία ) after its occupation by Phillip II of Macedon.
 It was considered a "polis" and an "emporion" at the same time.
 It is the only city of the Thasian "peraia" mentioned by Homer (as Ancient Greek: Αίσύμη ).
 Oisyme joined Brasidas after he captured Amphipolis along with Myrkinos and Galepsus.
Datos (Ancient Greek: Δάτος ) was an ancient Greek city located in Thrace, located in the region between the river Strymon and the river Nestos.It was founded by colonists from Thasos at 360 BC.Datos was founded with the help and support of the Athenian exiled orator, Callistratus of Aphidnae.
 Datos was close to Mount Pangaion with its rich gold veins and to another Thasian colony, Krenides.
The two colonies provoked the Thracians but at the same time gave Phillip II of Macedon the justification for penetrating the area and founding Philippi in 356 BC.
Cebrene (Ancient Greek: Κεβρήνη ), also spelled Cebren (Ancient Greek: Κεβρήν ), was an ancient Greek city in the middle Skamander valley in the Troad region of Anatolia.
 According to some scholars, the city's name was changed to Antiocheia in the Troad (Ancient Greek: Ἀντιόχεια τῆς Τρωάδος ) for a period during the 3rd century BCE (see below).
 Its archaeological remains have been located on Çal Dağ in the forested foothills of Mount Ida (modern Kaz Dağı), approximately 7 km to the south of the course of the Skamander.
 The site was first identified by the English amateur archaeologist Frank Calvert in 1860.
Krenides (Ancient Greek: Κρενίδες ) was an ancient Greek city located in Thrace, located in the region between the river Strymon and the river Nestos.
It was founded by colonists from Thasos at 360BC.
 Krenides was close to Mount Pangaion with its rich gold veins and to another Thasian colony, Datos.
The two colonies provoked the Thracians but at the same time gave Phillip II of Macedon the justification for penetrating the area and founding Philippi in 356 BC.Phillip intervened to protect the city when it was threatened by Thracians under Kersobleptes.
Stryme (Ancient Greek: Στρύμη ) was an ancient Greek city located in Thrace, located in the region between the river Nestos to the river Hebros.
 It was founded by colonists from Thasos.
 In some sources, Stryme is called a Thasian polis bordering on Mesambria, but the account Herodotos provides is contradictory.
 Stryme was located in the Briantike, a region belonging to the Thracian Kikones.
 The location of the site is disputed; many scholars locate it on the Molyvoti Peninsula about 25 km southwest of Komotini.
 This site is currently being investigated by a synergasia between the American School of Classical Studies at Athens, represented by Princeton University, and the 19th Ephorate of Prehistoric and Classical Antiquities (Komotini).
Smyrna (Ancient Greek: Σμύρνη or Σμύρνα ) was a Greek city dating back to antiquity located at a central and strategic point on the Aegean coast of Anatolia.
 This place was renamed to İzmir, Turkey.
 Due to its advantageous port conditions, its ease of defence and its good inland connections, Smyrna rose to prominence.
 Two sites of the ancient city are today within the boundaries of İzmir.
 The first site, probably founded by indigenous peoples, rose to prominence during the Archaic Period as one of the principal ancient Greek settlements in western Anatolia.
 The second, whose foundation is associated with Alexander the Great, reached metropolitan proportions during the period of the Roman Empire.
 Most of the present-day remains of the ancient city date from the Roman era, the majority from after a 2nd-century AD earthquake.
Myrkinos (Ancient Greek: Μύρκινος ) was an ancient Greek city located in Macedonian Thrace, in the region of Edonis between the Strymon and the Nestos Rivers.
 It was within the territory of the Edonians, a Thracian tribe, and was founded as a polis by colonists from Miletus in 497 BC.
 The colonists were led by Histiaios (already a Tyrant of Miletus), whom Darius had allowed to build a city in reward for his help.
 Myrkinos joined Brasidas after he captured Amphipolis, Oisyme and Galepsus in 422 BC.
 During the Byzantine empire it was known as Ancient Greek: Δοξόμπος or Δοξόμπους.
Histria or Istros (Ancient Greek: Ἰστρίη , Thracian river god, Danube), was a Greek colony or "polis" (πόλις, city) near the mouths of the Danube (known as Ister in Ancient Greek), on the western coast of the Black Sea.
 Histria is derived from the Latin word "Hister", meaning "Danube", the river the city was located near, and "-ia", a suffix added to a word to signify that it was a location or place, as in Gallia or Iberia.
 Altogether Histria means "On the Danube", "Located near (or by) - The Danube".
 It was the first urban settlement on Romanian territory when founded by Milesian settlers in the 7th century BC.
 It was under Roman rule from the 1st to 3rd centuries AD.
 Invasions during the 7th century AD rendered it indefensible, and the city was abandoned.
Phocaea, or Phokaia (Greek: Φώκαια ; modern-day Foça in Turkey) was an ancient Ionian Greek city on the western coast of Anatolia.
 Greek colonists from Phocaea founded the colony of Massalia (modern day Marseille, in France) in 600 BC, Emporion (modern day Empúries, in Catalonia, Spain) in 575 BC and Elea (modern day Velia, in Campania, Italy) in 540 BC.

Question: In what region was a city founded as a polis in 497 BC by colonists from an ancient Greek city on the western coast of Anatolia?
Answer: Edonis