Mark Jacobs is an American game designer, programmer, author and businessman, and the former GM/VP/CEO of Mythic Entertainment, Inc.
 He created two early MUDs, "Aradath" and Dragon's Gate serving as both the designer and programmer in addition to his duties as President/CEO.
 He founded A.U.S.I. (Adventures Unlimited Software Inc.) in 1983 and worked on a number of computer games for systems such as the Apple II.
 He is also a screenwriter, having penned a number of screenplays including one based on the game Imperator Online.
Betty Gleadle, {'1': ", '2': ", '3': ", '4': "} (11 December 1921 – 24 December 2016), known by the stage name Liz Smith, was an English character actress, known for her roles in BBC sitcoms, including as Annie Brandon in "I Didn't Know You Cared" (1975–79), Bette and Aunt Belle in "2point4 Children" (1991–99), Letitia Cropley in "The Vicar of Dibley" (1994–96), and Norma Speakman ("Nana") in "The Royle Family" (1998–2006).
 She also played Zillah in "Lark Rise to Candleford" (2008), and won the BAFTA Award for Best Actress in a Supporting Role for the 1984 film "A Private Function".
Polyploid cells and organisms are those containing more than two paired (homologous) sets of chromosomes. Most species whose cells have nuclei (Eukaryotes) are diploid, meaning they have two sets of chromosomes—one set inherited from each parent.
 However, polyploidy is found in some organisms and is especially common in plants.
 In addition, polyploidy occurs in some tissues of animals that are otherwise diploid, such as human muscle tissues.
 This is known as endopolyploidy.
 Species whose cells do not have nuclei, that is, Prokaryotes, may be polyploid organisms, as seen in the large bacterium "Epulopiscium fishelsoni" .
 Hence ploidy is defined with respect to a cell.
 Most eukaryotes have diploid somatic cells, but produce haploid gametes (eggs and sperm) by meiosis.
 A monoploid has only one set of chromosomes, and the term is usually only applied to cells or organisms that are normally diploid.
 Male bees and other Hymenoptera, for example, are monoploid.
 Unlike animals, plants and multicellular algae have life cycles with two alternating multicellular generations.
 The gametophyte generation is haploid, and produces gametes by mitosis, the sporophyte generation is diploid and produces spores by meiosis.
Painless, also known under its original title of Insensibles, is a 2012 fantasy horror film and the feature film directorial debut of Juan Carlos Medina.
 The film is a joint production between Spain, France, and Portugal and had its world premiere on 8 September 2012 at the Toronto International Film Festival.
 "Painless" is set in Catalonia and follows two different story lines, one set during the Spanish Civil War and one set in the modern day.
Susan Nickson is an English screenwriter, television producer, and script editor.
 She is the creator and writer of BBC sitcoms "Two Pints of Lager and a Packet of Crisps" (2001–2011) and "Grownups" (2006–2009).
Led Zeppelin Boxed Set 2 is a double album released by Atlantic Records on 21 September 1993.
 This box set features the rest of the English rock band Led Zeppelin's catalogue not included in the 1990 4-CD box set "Led Zeppelin", all digitally remastered, including the previously unreleased studio track "Baby Come On Home".
 A 54-page booklet was also included with the release.
 Between this box set and the 4-CD box set every track from the band's nine studio albums are featured along with two BBC live recordings; the band's only non-LP b-side; and one studio outtake.
Two Pints of Lager and a Packet of Crisps is a British sitcom that ran from 26 February 2001 to 24 May 2011.
 First broadcast on BBC Two, it starred Ralf Little, Will Mellor, Natalie Casey, Sheridan Smith, Kathryn Drysdale, and Luke Gell.
 Created and written by Susan Nickson, it was set in the northwest England town of Runcorn, and originally revolved around the lives of five twenty-somethings.
 Little departed after the sixth series finished airing, with Smith and Drysdale leaving following the airing of the eighth series.
 The ninth and final series had major changes with new main cast members and new writers.
Runcorn is a small industrial town in Halton, Cheshire, England, on the south bank of the River Mersey where it narrows at Runcorn Gap.
 In the town are the 61 buildings that are recorded in the National Heritage List for England as designated listed buildings in the current urban area of Runcorn, including the districts of Runcorn, Halton, Weston, Weston Point, and Norton.
 Two of these are classified as being in Grade I, nine in Grade II*, and fifty in Grade II.
 In the United Kingdom, the term "listed building" refers to a building or other structure officially designated as being of special architectural, historical or cultural significance.
 These buildings are in three grades: Grade I consists of buildings of outstanding architectural or historical interest; Grade II* includes particularly significant buildings of more than local interest; Grade II consists of buildings of special architectural or historical interest.
 Buildings in England are listed by the Secretary of State for Culture, Media and Sport on recommendations provided by English Heritage, which also determines the grading.
 The listed buildings are concentrated in Halton, which has 20, and Runcorn Town Centre, which has 16.
Matthew Francis is a British television and theatrical producer who is best known for his BBC sitcoms including My Dad's the Prime Minister, Gimme Gimme Gimme, and Office Gossip.
A typical large, double gamelan in contemporary Solo (Surakarta) will include, in the sléndro set, one saron panerus (or saron peking), two saron barung, one or two saron demung, one gendér panerus, one gender barung, one slenthem (or "gender panembung"), one bonang panerus and one bonang barung (each with twelve gongs), one gambang kayu, one siter or celempung, one rebab, one suling, one pair of kethuk and kempyang, one set of three to five kenong, one set of three to five kempul, one to three gong suwukan, and one gong ageng.

Question: Which English screenwriter created two BBC sitcoms including one set in the town of Runcorn?
Answer: Susan Nickson