The Lady Vanishes is a 1938 British mystery thriller film directed by Alfred Hitchcock, starring Margaret Lockwood and Michael Redgrave.
 Written by Sidney Gilliat and Frank Launder based on the 1936 novel "The Wheel Spins" by Ethel Lina White, the film is about a beautiful English tourist travelling by train in continental Europe who discovers that her elderly travelling companion seems to have disappeared from the train.
 After her fellow passengers deny ever having seen the elderly lady, the young woman is helped by a young musicologist, the two proceeding to search the train for clues to the old lady's disappearance.
Tuppence Middleton (born 21 February 1987) is an English actress.
 She was nominated for the London Evening Standard Film Awards 2010 for Most Promising Newcomer.
 Since 2015, she portrays Riley Blue in the Netflix webseries "Sense8".
The Wheel Spins (a.k.a.
 The Lady Vanishes) is a 1936 mystery novel by British writer Ethel Lina White.
Margaret Lockwood, CBE (15 September 1916 – 15 July 1990), was an English actress.
 One of Britain's most popular film stars of the 1930s and 1940s, her film appearances included "The Lady Vanishes" (1938), "Night Train to Munich" (1940), "The Man in Grey" (1943), and "The Wicked Lady" (1945).
 She was nominated for the BAFTA Award for Best British Actress for the 1955 film "Cast a Dark Shadow".
 She also starred in the 1970s television series "Justice" (1971–74)
Edward Black (18 August 1900, Birmingham - 30 November 1948, London) was an English film producer, best known for being head of production at Gainsborough Studios in the late 1930s and early 1940s, during which time he oversaw production of the Gainsborough melodramas.
 He also produced such classic films as "The Lady Vanishes" (1938).
 Black has been called "one of the unsung heroes of the British film industry."
The Lady Vanishes is a 1979 English comedy mystery film directed by Anthony Page.
 Its screenplay by George Axelrod was based on the novel "The Wheel Spins" by Ethel Lina White (1876–1944).
 It stars Elliott Gould as Robert, Cybill Shepherd as Amanda (Iris), Angela Lansbury as Miss Froy, Herbert Lom, Arthur Lowe and Ian Carmichael as Charters and Caldicott.
Examples of comedy thrillers in films, plays and novels are "Charade", "The Thin Man", "The Lady Vanishes", "In Bruges", "Silver Streak", "Mr. and Mrs. Smith", "No Way to Treat a Lady", "Kiss Kiss Bang Bang", "Kshana Kshanam", "The Big Fix", "Lucky Number Slevin", "Deathtrap", "The Ladykillers", "Hopscotch", "Welcome to Collinwood", "The King of Comedy".
Ethel Lina White (1876 – 13 August 1944) was a British crime writer, best known for her novel "The Wheel Spins" (1936), on which the Alfred Hitchcock film, "The Lady Vanishes" (1938), was based.
The Lady Vanishes is a 2013 British television mystery thriller film directed by Diarmuid Lawrence, and a co-production of the BBC and Masterpiece Films.
 It is based on the novel "The Wheel Spins" by Ethel Lina White (1876–1944).
 It stars Selina Cadell in the key role of the disappearing Miss Froy, Tuppence Middleton as the young Iris Carr (who discovers the disappearance, but is not taken seriously), and Tom Hughes and Alex Jennings as Max Hare and the Professor, the two fellow English passengers who come to her aid.
 It was watched by 7.44 million when it was broadcast on 17 March 2013 on BBC One.
Jenny Runacre (born 18 August 1946) is a South African-born English actress.
 Her film appearances include "The Passenger" (1975), "The Duellists" (1977), "Jubilee" (1978), "The Lady Vanishes" (1979), and "The Witches" (1990).

Question: Which actress plays both Iris Carr in The Lady Vanishes, and Riley Blue in Sense8?
Answer: Tuppence Middleton