Kœtzingue (] ; Alemannic German: "Ketzige" ; German: "Kötzingen" ) is a commune in the Haut-Rhin department in Alsace in north-eastern France.
Mondeuse noire is a red French wine grape variety that is grown primarily in the Savoy region of eastern France.
 The grape can also be found in Argentina, Australia, California, Switzerland and Sicily.
 Plantings of Mondeuse noire was hit hard during the phylloxera epidemic of the mid to late 19th century which nearly wiped out the vine from eastern France.
 While the grape recovered slightly in the 20th century, French plantations of Mondeuse noire fell sharply in the 1970s, with just over 200 ha left in France in 2000.
 In the early 21st century, it seems the variety has increased somewhat in popularity, as it can give good wines if the planting site is chosen carefully.
Vezet is a former commune in the Haute-Saône department in the region of Bourgogne-Franche-Comté in eastern France.
 On 1 January 2016, it was merged into the new commune La Romaine.
Alsace ( , ] ; Alsatian: "’s Elsass" ] ; German: "Elsass" ] ; Latin: "Alsatia" ) is a cultural and historical region in eastern France now located in the administrative region of Grand Est.
 Alsace is located on France's eastern border and on the west bank of the upper Rhine adjacent to Germany and Switzerland.
Taizé is a commune in the Saône-et-Loire department in the region of Bourgogne-Franche-Comté in eastern France.
 The commune lies 33 km northwest of Mâcon, the capital of Saône-et-Loire.
 Macon itself is south of the town of Cluny.
Levier is a commune in the Doubs department in the Bourgogne-Franche-Comté region in eastern France.
 On 1 January 2017, the former commune of Labergement-du-Navois was merged into Levier.
Auxonne is a French commune in the Côte-d'Or department in the Burgundy region of eastern France.
 The inhabitants of the commune are known as "Auxonnais" or "Auxonnaises".
Arbignieu is a former commune in the Ain department in the Auvergne-Rhône-Alpes region of eastern France.
 On 1 January 2016, it was merged into the new commune Arboys-en-Bugey.
Le Bois-d'Oingt is a former commune located in the Rhône in the Auvergne-Rhône-Alpes region, in eastern France.
 On 1 January 2017, Le Bois-d'Oingt, Oingt and Saint-Laurent-d'Oingt merged becoming one commune of Val d'Oingt.
Arlay is a commune in the Jura department in the region of Bourgogne-Franche-Comté in eastern France.
 On 1 January 2016, the former commune of Saint-Germain-lès-Arlay was merged into Arlay.

Question: Where is a cultural region in eastern France and is known to be the commune for Kœtzingue?
Answer: Alsace