Alejandro "Alex" Sosa is a fictional character and the main antagonist in the 1983 American crime film "Scarface" and the 2006 video game "".
 He is a Bolivian drug dealer and the chief supplier of cocaine for Tony Montana.
 Only when Sosa was felt betrayed did his relationship with Tony Montana end.
 Sosa is portrayed by Paul Shenar in the film and voiced by Robert Davi in the game.
 He is based on the Bolivian drug trafficker Roberto Suárez Goméz.
Frank Lucas (born September 9, 1930) is an American former drug trafficker, who operated in Harlem during the late 1960s and early 1970s.
 He was particularly known for cutting out middlemen in the drug trade and buying heroin directly from his source in the Golden Triangle.
 Lucas boasted that he smuggled heroin using the coffins of dead American servicemen, but this claim is denied by his South East Asian associate, Leslie "Ike" Atkinson.
 Rather than hide the drugs in the coffins, they were hidden in the pallets underneath as depicted in the 2007 feature film "American Gangster" in which he was played by Denzel Washington, although the film fictionalized elements of Lucas' life for dramatic effect.
Walter Douglas (born 1961) is an alleged Scottish drug trafficker and organised crime figure, dubbed the Tartan Pimpernel by the press, who is reportedly one of the richest in the United Kingdom with an estimated worth of £20 million.
 He was allegedly wanted in at least three countries on drug trafficking and gun running charges as of 2003, and Douglas was reported to have had ties to numerous international criminal organisations in Europe and North America as the head of the Delta crime syndicate.
 But in fact nothing has ever been proved against Douglas.
 In October 2013 there were no longer any warrants out against him and he staunchly maintained his innocence to a British journalist
Mickey Munday (born June 29, 1945) is an American former drug trafficker and former associate of Colombia's Medellin Cartel during the growth phase in cocaine trafficking, 1975–1985.
 Munday was featured in the 2006 Rakontur documentary, "Cocaine Cowboys."
George Jacob Jung (born August 6, 1942), nicknamed Boston George and El Americano, is a former drug trafficker and smuggler who was a major player in the cocaine trade in the United States in the 1970s and early 1980s.
 Jung was a part of the Medellín Cartel, which was responsible for up to 85 percent of the cocaine smuggled into the United States.
 He specialized in the smuggling of cocaine from Colombia on a large scale.
 His life story was portrayed in the biopic "Blow" (2001), starring Johnny Depp.
 Jung was released from prison on June 2, 2014, after serving nearly 20 years for drug-smuggling.
 On December 6, 2016 Jung was arrested and booked in Sacramento County jail for around a month, due to violating his parole.
 He was arrested while giving a speech in San Diego.
Rafael Cedeño Hernández is an imprisoned Mexican drug trafficker who was a high-level leader of La Familia Michoacana, a drug cartel based in the Mexican state of Michoacán.
 He was the successor of Alberto Espinoza Barrón, a drug trafficker who was arrested on 31 December 2008 by the Mexican authorities.
Rafael Caro Quintero (born October 3, 1952) is a Mexican drug trafficker who founded the now-disintegrated Guadalajara Cartel with Miguel Ángel Félix Gallardo and other drug traffickers in the 1970s.
 He is the brother of fellow drug trafficker Miguel Caro Quintero, the founder and former leader of the extinct Sonora Cartel who remains incarcerated.
Richard "Pee Wee" Kirkland (born May 6, 1945) is a former street basketball player and a former drug trafficker.
Héctor Manuel Sauceda Gamboa (died 17 February 2009), commonly referred to by his alias El Karis, was an alleged drug trafficker and high-ranking leader of the Gulf Cartel (Spanish: "Cártel del Golfo"), a Mexican drug trafficking organization.
 He was the brother of the drug lord Gregorio Sauceda Gamboa, another high-ranking drug trafficker who worked under the tutelage of Osiel Cárdenas Guillén, the former top leader of the cartel.
American Gangster is a 2007 American biographical crime film directed and produced by Ridley Scott and written by Steven Zaillian.
 The film is fictionally based on the criminal career of Frank Lucas, a gangster from La Grange, North Carolina who smuggled heroin into the United States on American service planes returning from the Vietnam War, before being detained by a task force led by detective Richie Roberts.
 The film stars Russell Crowe and Denzel Washington in their first lead acting roles together since 1995's "Virtuosity".
 The film also co-stars Ted Levine, John Ortiz, Josh Brolin, Chiwetel Ejiofor, Norman Reedus, Ruby Dee, Lymari Nadal and Cuba Gooding Jr.

Question: This biographical crime film is fictionally based on the criminal career of an American former drug trafficker, who operated in what city?
Answer: Harlem