Frank Lucas (born September 9, 1930) is an American former drug trafficker, who operated in Harlem during the late 1960s and early 1970s.
 He was particularly known for cutting out middlemen in the drug trade and buying heroin directly from his source in the Golden Triangle.
 Lucas boasted that he smuggled heroin using the coffins of dead American servicemen, but this claim is denied by his South East Asian associate, Leslie "Ike" Atkinson.
 Rather than hide the drugs in the coffins, they were hidden in the pallets underneath as depicted in the 2007 feature film "American Gangster" in which he was played by Denzel Washington, although the film fictionalized elements of Lucas' life for dramatic effect.
Rafael Caro Quintero (born October 3, 1952) is a Mexican drug trafficker who founded the now-disintegrated Guadalajara Cartel with Miguel Ángel Félix Gallardo and other drug traffickers in the 1970s.
 He is the brother of fellow drug trafficker Miguel Caro Quintero, the founder and former leader of the extinct Sonora Cartel who remains incarcerated.
Mickey Munday (born June 29, 1945) is an American former drug trafficker and former associate of Colombia's Medellin Cartel during the growth phase in cocaine trafficking, 1975–1985.
 Munday was featured in the 2006 Rakontur documentary, "Cocaine Cowboys."
American Gangster is a 2007 American biographical crime film directed and produced by Ridley Scott and written by Steven Zaillian.
 The film is fictionally based on the criminal career of Frank Lucas, a gangster from La Grange, North Carolina who smuggled heroin into the United States on American service planes returning from the Vietnam War, before being detained by a task force led by detective Richie Roberts.
 The film stars Russell Crowe and Denzel Washington in their first lead acting roles together since 1995's "Virtuosity".
 The film also co-stars Ted Levine, John Ortiz, Josh Brolin, Chiwetel Ejiofor, Norman Reedus, Ruby Dee, Lymari Nadal and Cuba Gooding Jr.
Richard "Pee Wee" Kirkland (born May 6, 1945) is a former street basketball player and a former drug trafficker.
Frank "Black Caesar" Matthews (born February 13, 1944) is a major heroin and cocaine trafficker who operated throughout the eastern seaboard during the late 1960s and early 1970s.
 At the peak of his career he operated in 21 states and supplied major dealers throughout every region of the country.
 Although there is more attention paid to other drug kingpins of the era, Frank Matthews is said by the DEA to be one of the most significant traffickers of the time.
 He led a flamboyant lifestyle, with large sable mink coats, prime seats at major sporting events, luxury vehicles, and regular trips to Las Vegas where he was treated like a king.
 Matthews would also become known for hosting a major African-American drug dealers "summit" in Atlanta in 1971.
 The attendee list, gathered by DEA surveillance, was a who's who of most major African-American and Hispanic dealers throughout the country; they were all there to discuss how to break the Italian Mafia's control of heroin importation so that black drug dealers would not have to rely on them in the future.
Bhupinder "Bindy" Singh Johal (January 14, 1971 – December 20, 1998) was an Indian born gangster who was raised in, and operated in, British Columbia, Canada.
 A self-confessed drug trafficker; he was known for his outspoken nature and blatant disregard for authority.
 His quote ".
.
I'm still around" has been sensationalized by Canadian pop-culture.
 On December 20, 1998, he was killed from behind at a crowded nightclub in Vancouver, British Columbia.
Rafael Cedeño Hernández is an imprisoned Mexican drug trafficker who was a high-level leader of La Familia Michoacana, a drug cartel based in the Mexican state of Michoacán.
 He was the successor of Alberto Espinoza Barrón, a drug trafficker who was arrested on 31 December 2008 by the Mexican authorities.
George Jacob Jung (born August 6, 1942), nicknamed Boston George and El Americano, is a former drug trafficker and smuggler who was a major player in the cocaine trade in the United States in the 1970s and early 1980s.
 Jung was a part of the Medellín Cartel, which was responsible for up to 85 percent of the cocaine smuggled into the United States.
 He specialized in the smuggling of cocaine from Colombia on a large scale.
 His life story was portrayed in the biopic "Blow" (2001), starring Johnny Depp.
 Jung was released from prison on June 2, 2014, after serving nearly 20 years for drug-smuggling.
 On December 6, 2016 Jung was arrested and booked in Sacramento County jail for around a month, due to violating his parole.
 He was arrested while giving a speech in San Diego.
Héctor Manuel Sauceda Gamboa (died 17 February 2009), commonly referred to by his alias El Karis, was an alleged drug trafficker and high-ranking leader of the Gulf Cartel (Spanish: "Cártel del Golfo"), a Mexican drug trafficking organization.
 He was the brother of the drug lord Gregorio Sauceda Gamboa, another high-ranking drug trafficker who worked under the tutelage of Osiel Cárdenas Guillén, the former top leader of the cartel.

Question: American Gangster is fictionally based on an American former drug trafficker, who operated where in the late 1960s and early 1970s?
Answer: Harlem