Jacob R. Brussel (June 21, 1899 – October 1979) was an antiquarian bookseller and publisher in New York City whose firm J.R. Brussel also dealt in erotica.
 For many years Brussel operated a shop, under various names including Atlantis and Ortelius, on New York's famous Fourth Avenue book row, initially in partnership with Samuel Weiser as "Weiser's Book Shop" until Weiser moved out to open his own shop across the street.
 He published large numbers of erotic and sexological reprints of works in the public domain in small editions, employing a job printer in a cellar around the corner, as well as the unauthorized bootleg "Medvsa" edition of "Tropic of Cancer" by Henry Miller and the first part of "Oragenitalism" by Gershon Legman, a young employee in the Brussel bookshop.
 Others who worked in the shop in this era included Sol M. Malkin, (later the founder of "AB Bookman's Weekly"), Keene Wallis, and Mahlon Blaine.
 The shop's book scout was Jake's brother Ike Brussel, later billed as "the last of the great scouts".
 In early 1940 the shop was raided by police and Brussel was sentenced to three years in jail on obscenity charges.
 After the war he carried on the storefront business while focusing largely on publishing under various imprints, including Brussel and Brussel, New York Medical Press, and United Book Guild.
The Boreel, later Boreel Baronetcy, of Amsterdam in the Netherlands, is a title in the Baronetage of England.
 It was created on 21 March 1645 for William Boreel.
 He was Dutch Ambassador to England, Sweden and Venice.
 The title descended in the direct line until the death of his grandson, the third Baronet, in 1710.
 The late Baronet died unmarried and was succeeded by his younger brother, the fourth Baronet.
 He died without male issue and was succeeded by his first cousin, the fifth Baronet.
 He was the son of James Boreel, younger son of the first Baronet.
 He died childless and was succeeded by his nephew, the sixth Baronet.
 He was the son of James Boreel, younger brother of the fifth Baronet.
 He never married and was succeeded by his first cousin once removed, the seventh Baronet.
 He was the grandson of John Hieronymous Boreel, younger brother of the fifth Baronet.
 His son, the eighth Baronet, was created a Jonkheer in the Dutch nobility.
 The title descended from father to son until the death of his grandson, the tenth Baronet, in 1937.
"Cartman Gets an Anal Probe" is the first episode of the American animated television series "South Park".
 It first aired on Comedy Central in the United States on August 13, 1997.
 The episode introduces child protagonists Eric Cartman, Kyle Broflovski, Stan Marsh and Kenny McCormick, who attempt to rescue Kyle's younger brother Ike from being abducted by aliens.
"Miss Teacher Bangs a Boy" is the tenth episode in the tenth season of the American animated television series "South Park".
 The 149th episode of the series overall, it originally aired on Comedy Central in the United States October 18, 2006.
 In the episode, Kyle's little brother Ike begins a romantic relationship with his kindergarten teacher Miss Stevenson, while Cartman becomes the hall monitor at school.
 It features a parody of the television series "Dog the Bounty Hunter".
"Taming Strange" is the fifth episode in the seventeenth season of the American animated television series "South Park".
 The 242nd episode of the series overall, it premiered on Comedy Central in the United States on October 30, 2013.
 This episode parodies Miley Cyrus' controversial performance at the 2013 MTV Video Music Awards through the use of "Yo Gabba Gabba!
", as well as the technical problems encountered during the launch of the HealthCare.gov website.
 The central focus of the plot revolves around Kyle trying to bond with his baby brother Ike, who is suddenly going through puberty.
The O.K. Corral hearing and aftermath was the direct result of the 30-second Gunfight at the O.K. Corral in Tombstone, Arizona Territory on October 26, 1881.
 During that confrontation, Deputy U.S. Marshal and Tombstone Town Marshal Virgil Earp, Assistant Town Marshal Morgan Earp, and temporary deputy marshals Wyatt Earp and Doc Holliday shot and killed Billy Clanton, and Tom and Frank McLaury.
 Billy's brother Ike, who had repeatedly threatened to kill the Earps for some time, had been present at the gunfight but was unarmed and fled.
 He filed murder charges against the Earps and Doc Holliday on October 30.
William Harrison Clanton (1862 – October 26, 1881) was an outlaw Cowboy in Cochise County, Arizona Territory.
 He, along with his father Newman Clanton and brother Ike Clanton, worked a ranch near Tombstone and stole livestock from Mexico and later U.S. ranchers.
Wendy Testaburger is a fictional character in the American animated series "South Park".
 The series' most prominent female character, she is best known for her on-again, off-again relationship with her boyfriend, Stan Marsh, and being more intelligent and mature than most children her age, which is utilized by her activism and feminism.
 Wendy debuted as a nameless background character in Trey Parker and Matt Stone's 1995 college short film, "The Spirit of Christmas", and made her first appearance on television when "South Park" initially premiered on Comedy Central on August 13, 1997 with the episode "Cartman Gets an Anal Probe".
 She is currently voiced by April Stewart.
 Prior, she had been voiced by several different voice actors throughout the show's run: Mary Kay Bergman, Eliza Schneider, and Mona Marshall.
The Rogers Baronetcy, of Wisdome in the County of Devon, was a title in the Baronetage of England.
 It was created in 1699 for John Rogers, a merchant and Member of Parliament for Plymouth.
 His son, the second Baronet, and grandson, the third Baronet, also represented Plymouth in Parliament.
 The latter was childless and was succeeded by his younger brother, the fourth Baron.
 He was a Captain in the Royal Navy.
 His son, the fifth Baronet, sat as Member of Parliament for Plymouth.
 He was succeeded by his eldest son, the sixth Baronet.
 He sat as Member of Parliament for Callington and was also a composer.
 He was unmarried and was succeeded by his younger brother, the seventh Baronet.
 The latter was succeeded by his eldest son, the eighth Baronet.
 He was a prominent civil servant and notably served as Permanent Under-Secretary of State for the Colonies from 1860 to 1871.
 In 1871 he was elevated to the Peerage of the United Kingdom as Baron Blachford, of Wisdome and of Blachford in the County of Devon (Blachford House, Cornwood, near Ivybridge).
 He died childless in 1889 when the barony became extinct.
 He was succeeded in the baronetcy by his younger brother, the ninth Baronet.
 The latter was in his turn succeeded by another brother, the tenth Baronet, on whose death in 1895 the baronetcy became extinct as well.
"Ike's Wee Wee" is the third episode in the second season of the American animated television series "South Park".
 The 17th episode of the series overall, it first aired on Comedy Central in the United States on May 20, 1998.
 In the episode, school counselor Mr. Mackey is fired, and turns to drugs.
 Meanwhile, the boys misconstrue what circumcision entails, and try to save Kyle's younger brother Ike from his upcoming bris.

Question: Who are the creators of the show that has an episode in which Kyle's younger brother Ike is being abducted by aliens?
Answer: Trey Parker and Matt Stone