Somatostatin subject has role hormone
Functions
Somatostatin is classified as an inhibitory hormone, and is induced by low pH. Its actions are spread to different parts of the body. Somatostatin release is inhibited by the Vagus nerve.Inhibiting the release of growth hormone (GH) (thus opposing the effects of growth hormone–releasing hormone (GHRH))
Inhibiting the release of thyroid-stimulating hormone (TSH)
Inhibiting adenylyl cyclase in parietal cells
Inhibiting the release of prolactin (PRL)Gastrointestinal system
Somatostatin is homologous with cortistatin (see somatostatin family) and suppresses the release of gastrointestinal hormones
Decreases the rate of gastric emptying, and reduces smooth muscle contractions and blood flow within the intestine
Suppresses the release of pancreatic hormones
Somatostatin release is triggered by the beta cell peptide urocortin3 (Ucn3) to inhibit insulin release.
Inhibits the release of glucagon
Suppresses the exocrine secretory action of the pancreas
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