Leonardo (ISS module) significant event maiden flight
As an MPLM
The Leonardo MPLM, also known as MPLM-1, was one of three Multi-Purpose Logistics Modules which were operated by NASA to transfer supplies and equipment to and from the International Space Station. Leonardo was used for eight of the twelve MPLM flights to the space station, with Raffaello being used for the other four. It was the first MPLM to be launched, making its first flight in March 2001, aboard Space Shuttle Discovery on STS-102.