Noracymethadol instance of type of chemical entity
Noracymethadol (INN) is a synthetic opioid analgesic related to methadone that was never marketed. In a clinical trial of postpartum patients it was reported to produce analgesia comparable to that of morphine but with less nausea, dizziness, and drowsiness. Other side effects included salivation, ataxia, and respiratory depression that was reversible by naloxone. Similarly to many of its analogues, noracymethadol is a Schedule I controlled substance in the United States with an ACSCN of 9633 and 2013 annual manufacturing quota of 12 grammes.  and is also controlled internationally under the United Nations Single Convention on Narcotic Drugs of 1961.  The salts known are the gluconate (free base conversion ratio 0.633) and hydrochloride (0.903).
Noracymethadol is an acetyl ester of methadol and it can be said with some precision that it is either the heroin or 6-monoacetylmorphine analogue of methadol, and being a methadol it exhibits optical isomerism.  The other methadols (acetylmethadol, methadol &c) have at least four optical isomers (see Orlaam).
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