Red blood cells no relation mountaineering
Physiological background
The human body has optimal endurance below 150 m (490 ft) elevation. The concentration of oxygen (O2) in air is 20.9% so the partial pressure of O2 (PO2) at sea level is about 21.2 kPa (6.3 inHg; 3.07 psi). In healthy
individuals, this saturates hemoglobin, the oxygen-binding red pigment in red blood cells.Atmospheric pressure decreases with altitude while the O2 fraction remains constant to about 85 km (53 mi), so PO2 decreases with altitude as well. It is about half of its sea level value at 5,500 m (18,000 ft), the altitude of the Mount Everest base camp, and less than a third at 8,849 m (29,032 ft), the summit of Mount Everest. When PO2 drops, the body responds with altitude acclimatization. Additional red blood cells are manufactured; the heart beats faster; non-essential body functions are suppressed, food digestion efficiency declines (as the body suppresses the digestive system in favor of increasing its cardiopulmonary reserves); and one breathes more deeply and more frequently. But acclimatization requires days or even weeks. Failure to acclimatize may result in altitude sickness, including high-altitude pulmonary edema (HAPE) or cerebral edema (HACE).Humans have survived for 2 years at 5,950 m (19,520 ft) [475 millibars (14.0 inHg; 6.89 psi) of atmospheric pressure], which appears to be near the limit of the permanently tolerable highest altitude. At extreme altitudes, above 7,500 m (24,600 ft) [383 millibars (11.3 inHg; 5.55 psi) of atmospheric pressure], sleeping becomes very difficult, digesting food is near-impossible, and the risk of HAPE or HACE increases greatly.
no relation