Cough suppression no relation medication
Medical uses
Cough suppression
The primary use of dextromethorphan is as a cough suppressant, for the temporary relief of cough caused by minor throat and bronchial irritation (such as commonly accompanies the flu and common cold), or from inhaled particle irritants, as well as chronic cough at a higher dosage. Dextromethorphan is available alone in the form of cough syrup and pills as well as in combination with other agents.Pseudobulbar affect
In 2010, the FDA approved the combination drug dextromethorphan/quinidine under the brand name Nuedexta for the treatment of pseudobulbar affect (uncontrollable laughing/crying). Dextromethorphan is the actual therapeutic agent in the combination; quinidine merely serves to inhibit the enzymatic degradation of dextromethorphan and thereby increase its circulating concentrations via inhibition of CYP2D6.Major depressive disorder
The combination medicine dextromethorphan/bupropion is approved for major depressive disorder under the brand name Auvelity. Dextromethorphan acts on the NMDA receptor.
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