Pearl Slaghoople performer Janet Waldo
Voice cast
Alan Reed – Fred Flintstone, Uncle Ghastly
Jean Vander Pyl – Wilma Flintstone, Pebbles Flintstone
Mel Blanc – Barney Rubble, Dino, Zack Hatrock
Daws Butler – Barney Rubble (Season 2; episodes 1, 2, 5, 6 and 9 only)
Bea Benaderet – Betty Rubble (Seasons 1–4), Gravella Hatrock
Gerry Johnson – Betty Rubble (Seasons 5–6), Granny Hatrock (in "The Hatrocks and the Gruesomes")
Don Messick – Bamm-Bamm Rubble, Hoppy, Arnold, Gobby Gruesome
John Stephenson – Mr. Slate, Joe Rockhead, Sam Slagheap
Verna Felton – Wilma's mother (Seasons 2 and 3)
Janet Waldo – Pearl Slaghoople (Seasons 4 and 6)
Harvey Korman – The Great Gazoo