Spanish ship Santa Ana (1784) participant Battle of Trafalgar
From 1803 to 1804 she was captained by Dionisio Alcalá Galiano. At Trafalgar she was the flagship of Teniente-General Ignacio Maria de Álava y Sáenz de Navarrete and captained by José Ramón de Gardoqui - she suffered 97 killed and 141 wounded, with Alava himself seriously wounded, and was captured by the British. However, two days later, a squadron under the command of Commodores Enrique Macdonell and Cosmao-Kerjulien sallied from Cadiz and succeeded in recapturing her and getting her back to Cadiz.
At the start of the Peninsular War in 1808 she was undergoing repairs at the Arsenal and so could not participate in the capture of the French squadron under Admiral Rosily. She and her sistership Príncipe de Asturias moved to Havana in late 1810 to avoid capture by the French, and sank in its Arsenal in 1816. In 1834 she could still be seen next to the Príncipe de Asturias (which had also sunk) in the mud in front of the Arsenal.