Alex Ríos participant of 2010 Major League Baseball season
Chicago White Sox
After being claimed off of waivers by the Chicago White Sox on August 10, Ríos batted .199, with three home runs, 9 RBI and a .296 on-base percentage in 146 at bats over 41 games. Rios batted .284, with 21 home runs, 88 RBI and a .334 on-base percentage for the White Sox in 2010. After a disappointing 2011 season in which he batted a career-low .227, Ríos rebounded to have one of his finest years in 2012, setting career highs with a .304 average, 25 home runs and 91 RBIs.
On July 9, 2013, Rios collected six hits in a game (tied AL record) in an 11–4 win over the Tigers. Ríos was the starting right fielder for 2013 until his trade. After the trade, Jordan Danks and Avisail García took over. In 599 games over five years for Chicago, he hit .269/.310/.430 with 74 home runs, 287 RBI, and 99 stolen bases.