Question: what episode do cristina and owen break up

title: Cristina Yang
text: Cristina is re-hired and Owen asks for a divorce once Cristina wants to reconcile . Shocked , Cristina agrees , but later finds out that the potential conflict of interest regarding the plane crash lawsuit was a key motive behind Owen 's request and confronts him . Owen tells her that he ' feels responsible ' and was worried as he thought she was dead . They have a sexual relationship after divorcing . The hospital is sued and found guilty of negligence . The surviving doctors , including Yang , must receive $15 million of compensation each , which leads the hospital to a near bankruptcy as the insurers refuse to pay . Yang , Callie Torres ( Sara Ramirez ) , and the other surviving doctors buy the hospital with the help of the Harper - Avery Foundation to prevent it from closing , and each become members of the new directing board . After buying the hospital , Yang realizes that she was made for the O.R. and breaks things off with Owen because he still wants kids and she still does n't . 

Answer: answer: Cristina Yang realizes after buying the hospital, that she was made for the O.R. and breaks things off with Owen as  he still wants kids and she still does not .