Question: when did uncle ben say with great power comes great responsibility

title: Uncle Ben
text: The thematic and often - quoted ( including by the Supreme Court of the United States ) Spider - Man phrase with great power comes great responsibility is widely attributed to Uncle Ben . However , in Amazing Fantasy # 15 , where it first appears , it is not spoken by any character . In fact , Ben has only two lines in the entire comic . The original version of the phrase appears in a narrative caption of the comic 's last panel , rather than as spoken dialogue . It reads , `` ... with great power there must also come -- great responsibility ! '' . 

Answer: answer: When it first appears, it is not spoken by any character. The original version of the phrase appears in a narrative caption of the comic's last panel.