Question: when was a cure for bubonic plague found

title: Bubonic plague
text: The first recorded epidemic affected the Eastern Roman Empire ( Byzantine Empire ) and was named the Plague of Justinian after emperor Justinian I , who was infected but survived through extensive treatment . The pandemic resulted in the deaths of an estimated 25 million ( 6th century outbreak ) to 50 million people ( two centuries of recurrence ) . The historian Procopius wrote , in Volume II of History of the Wars , of his personal encounter with the plague and the effect it had on the rising empire . In the spring of 542 , the plague arrived in Constantinople , working its way from port city to port city and spreading around the Mediterranean Sea , later migrating inland eastward into Asia Minor and west into Greece and Italy . Because the infectious disease spread inland by the transferring of merchandise through Justinian 's efforts in acquiring luxurious goods of the time and exporting supplies , his capital became the leading exporter of the bubonic plague . Procopius , in his work Secret History , declared that Justinian was a demon of an emperor who either created the plague himself or was being punished for his sinfulness .