Hemolithin

Hemolithin (sometimes confused with the similar space polymer Hemoglycin) is a proposed protein containing iron and lithium, of extraterrestrial origin, according to an unpublished preprint. The result has not been published in any peer-reviewed scientific journal. The protein was purportedly found inside two CV3 meteorites, Allende and Acfer-086, by a team of scientists led by Harvard University biochemist Julie McGeoch. The report of the discovery was met with some skepticism and suggestions that the researchers had extrapolated too far from incomplete data.
Sources
The detected hemolithin protein was reported to have been found inside two CV3 meteorites Allende and Acfer 086. Acfer-086, where the complete molecule was detected rather than fragments (Allende), was discovered in Agemour, Algeria in 1990.
Structure
According to the researchers' mass spectrometry, hemolithin is largely composed of glycine and hydroxyglycine amino acids. The researchers noted that the protein was related to “very high extraterrestrial" ratios of Deuterium/Hydrogen (D/H); such high D/H ratios are not found anywhere on Earth, but are "consistent with long-period comets" and suggest, as reported, "that the protein was formed in the proto-solar disc or perhaps even earlier, in interstellar molecular clouds that existed long before the Sun’s birth".
A natural development of hemolithin may have started with glycine forming first, and then later linking with other glycine molecules into polymer chains, and later still, combining with iron and oxygen atoms. The iron and oxygen atoms reside at the end of the newly found molecule. The researchers speculate that the iron oxide grouping formed at the end of the molecule may be able to absorb photons, thereby enabling the molecule to split water (H2O) into hydrogen and oxygen and, as a result, produce a source of energy that might be useful to the development of life.
Exobiologist and chemist Jeffrey Bada expressed concerns about the possible protein discovery commenting, "The main problem is the occurrence of hydroxyglycine, which, to my knowledge, has never before been reported in meteorites or in prebiotic experiments. Nor is it found in any proteins. ... Thus, this amino acid is a strange one to find in a meteorite, and I am highly suspicious of the results." Likewise, Lee Cronin of the University of Glasgow stated, "The structure makes no sense."
History
Hemolithin is the name given to a protein molecule isolated from two CV3 meteorites, Allende and Acfer-086. Its deuterium to hydrogen ratio is 26 times terrestrial which is consistent with it having formed in an interstellar molecular cloud, or later in the protoplanetary disk at the start of the Solar System 4.567 billion years ago. The elements hydrogen, lithium, carbon, oxygen, nitrogen and iron that it is composed of, were all available for the first time 13 billion years ago after the first generation of massive stars ended in nucleosynthetic events.
The research leading to the discovery of Hemolithin started in 2007 when another protein, one of the first to form on Earth, was observed to entrap water. That property being useful to chemistry before biochemistry on earth developed, theoretical enthalpy calculations on the condensation of amino acids were performed in gas phase space asking: “whether amino acids could polymerize to protein in space?” - they could, and their water of condensation aided their polymerization. This led to several manuscripts of isotope and mass information on Hemolithin.
See also
Earliest known life forms
Evolutionary history of life
Extraterrestrial: The First Sign of Intelligent Life Beyond Earth
List of interstellar and circumstellar molecules
Panspermia
References
Astrobiology
Biological hypotheses
Iron compounds
Lithium compounds
Organolithium compounds
Origin of life
Panspermia
Prebiotic chemistry
Proteins