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1. H. Tamura, A. Ohtsuru, Y. Kamohara, H. Fujioka, K. Yanaga, T. Kanematsu, S. Yamashita: Bax cleavage implicates caspase-dependent H2O2-induced apoptosis of hepatocytes. Int J  Mol  Med  11: 369-374, 2003 ↑〇2. A. Podotcheko, A. Ohtsuru, S. Tsuda, H. Namba, V. Saenko, M. Nakashima, N. Mitsutake, S. Kanda, J. Kurebayashi, S. Yamashita: The selective tyrosine kinase inhibitor, STI571, inhibits the growth of anaplastic thyroid cancer cells. J  Clin  Endocrinol  Metab 88(4): 1889–1896, 2003  ⋆  ⋆ 3. T. Daian, A. Ohtsuru, T. Rogounovitch, H. Ishihara, A. Hirano, Y. Akiyama-Uchida, V. Saenko, T. Fujii, S. Yamashita: IGF-I enhances TGF-beta-induced extracellular matrix protein production through the p38/ATF -2 signaling pathway in keloid fibroblasts. J Invest Dermatol 120(6): 956-962, 2003 ↑〇◎ 4 . M. Nakashima, T. Nakayama, A. Ohtsuru, E. Fukuda, D. Niino, K. Yamazumi, S. Naito, M. Ito, I. Sekine: Expression of parathyroid hormone (PTH)-related peptide (PTHrP) and PTH/PTHrP receptor in osteoclast -like giant cells. Pathol  Res  Pract  199(2): 85-92, 2003  * 5． V. Saenko, T. Rogounovitch, Y. S-Yoshida, A. Abrosimov, E. Lushnikov, P. Roumiantsev, N. Matsumoto, M. Nakashima, S. Meirmanov, A. Ohtsuru, H. Namba, A. Tsyb, S. Yamashita: Novel tumorigenic rearrangement, delta-rfp/ret, in a papillary thyroid carcinoma from externally irradiated patient. Mutat Res 527: 81-90, 2003 * ☆ 6 . H. Namba, M. Nakashima, T. Hayashi, N. Hayashida, S. Maeda, TI. Rogounovitch, A. Ohtsuru, VA. Saenko, T. Kanematsu, S. Yaashita: Clinical implication of hot spot BRAF mutation V599E, in papillary thyroid cancers. J  Clin Endocrinol  Metab 88(9): 4393-4397, 2003  ⋆  ◎ 7. A. Podtcheko, A. Ohtsuru, H. Namba, V. Saenko, S. Yamashita: Authors' Response: Effect of imatinib messylate (gleevee) on anaplastic thyroid carcinoma cell line. J Clin Endocrinol Metab 88(10): 5044, 2003 * 8. Y. Kanazawa, H. Isomoto, C.Y. Wen, A.P. Wang, V.A. Saenko, A. Ohtsuru, F. Takeshima, K. Omagari, Y. Mizuta, I. Murata, S. Yamashita, S. Kohno: Impact of endoscopically minimal involvement on IL-8 mRNA expression in esophageal mucosa of patients with non-erosive reflux disease. World J  Gastroenterol 9 (12): 2801 -2804, 2003  ⋆ O 9 .  M. Ito, M. Nakashima, T. Nakayama, S. Shikuwa, A. Ohtsuru, I. Sekine: Preventive effects of parathyroid hormone-related peptide on stresss-induced gastric hypercontraction in the rat. J Gastroenterol Hepatol 17 (12): 1260-1266, 2003  * ★ 10. C.W. Wen, M. Ito, L-D. C, M. Matsuu, K. Shichijo, T. Nakayama, M. Nakashima, Z-M. X, A. Ohtsuru, C-T. Hsu, I. Sekine: Expression of Tie-2 and angiopoietin-1 and -2 in early phase of ulcer healing. J  Gastroenterol 38: 431-435, 2003  *
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1. A. Ohtsuru, A. Podtcheko, S. Tsuda, H. Namba, H. Tamura, VA. Saenko, M., Morishita, M. Iwamatsu, S. Yamashita: A novel radiosensitizung therapy for anaplastic thyroid cancers. Radiation and Humankind, International Congress Series 1258, 273, 2003 2. A. Podtcheko, A. Ohtsuru, S. Tsuda, H. Namba, V. Saenko, M. Nakashima, N. Mitsutake, S. Kanda, J. Kurebayashi, S. Yamashita: The selectie tyrosine kinase inhibitor, ST1571, inhibits growth of anaplastic thyroid cancer cells by inducing S-G2 transition. Radiation and Humankind, International Congress Series 1258, 157, 2003 3. T. Rogounovitch, V. A. Saenko, Y. Shimizu-Yoshida, A. Y. Abrosimov, E. F. Lushnikov, P. O. Roumiantsev, A. Ohtsuru, H. Namba, S. Yamashita: Molecular features of mitochondrial DNA in radiation-associated thyroid tumors. Radiation and Humankind, International Congress Series 1258, 163, 2003 4 . D.V. Starenki, H. Namba, V.A. Saenko, A. Ohtsuru, S. Yamashita: Modulation of radiosensitivity of thyroid cancer cells by inhibition of NF-kB signaling, Radiation and Humankind, International Congress Series 1258, 147, 2003 5 .  G. Yanase, A. Ohtsuru, S. Yamashita: Depsipeptide, a histone deacetylase inhibitor, enhances apoptotic killing for undifferentiated thyroid cancers by p53 gene therapy in vitro and in vivo. Leiden International Medical Student Congress 2003 (3/14-15, Leiden, Netherland, 2003) 6 . A. Ohtsuru, A. Podtcheko, H. Namba, S. Yamashita: A novel and promising therapy for anaplastic thyroid cancers. The Endocrine Society's 85th Annual Meeting (6/19-22, Philadelphia, USA, 2003) 7 .  M. Morishita, A. Ohtsuru, S. Yamashita, T. Kanematsu, N. Yamashita: Thyroglobulin-pulsed human monocyte -derived dendritic cells induce CD4+T cell activation. The Endocrine Society's 85th Annual Meeting (6/19-22, Philadelphia, USA, 2003) 8 . H. Namba, A. Ohtsuru, S. Yamashita: Clinical implication of hot spot BRAF mutation, V599E, in papillary thyroid cancers. European Thyroid Association Annual Meeting 2003 (10/18-22, Edinburgh, Scotland, 2003) 9 .  D. Starenki, H. Namba, V. Saenko, A. Ohtsuru, S. Yamashita: Inhibition of NF-xB potentiates radiosensitivity of thyroid cancer cells. 7 th Ashia-Oceania Thyroid Association Congress (12/2-4, Singapore, 2003)
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1．大津留晶、寒川賢治、兼松隆之、山下俊一：宵切除後症状の病態解明とグレリン臨床研究の展望、(国立循環器センターCOEプロジェクト第１回グレリンシンポジウム、３／18、2003) 2．秋野公造、秋田定伯、大津留品、山下俊一：骨欠損に対する再生医療法の開発、日本内分泌学会雑誌、79(1)：120、 2003 3．難波裕宰、前田茂人、中島正洋、林徳眞吉、大津留品、山下俊一：甲状腺がんにおけるBRaf変異とMAPK経路の活性化、日本内分泌学会雑誌、79(1)：138、2003 4．高村　昇、濱田亜衣子、大津留晶、古市　哲、永田康人、円城寺昭人、兼松隆之、下川　功、細田洋二、寒川賢治、山下俊一：宵切除後におけるグレリン分泌と体重調節、日本内分泌学会雑誌、79(1)：181、2003 5．D. Starenki、難波裕幸、大津留　品、山下俊一、V. Saenko：NF-xB活性阻害による甲状腺癌放射験療法の感受性増強効果、第44回原子爆弾後障害研究会抄録集、32、2003 6．難波裕幸、V. Saenko、大津留品、山下俊一：甲状腺がん組織におけるBRAF変異の解析、第44回原子爆弾後障害研究会抄録集、33、2003 7．大津留品、磯本　一、岩松みよ子、山下俊一：がん温熱遺伝子治療の開発、Jpn J Hyperthermic Oncology 19 (suppl): 72, 2003 8 、難波裕幸、熊谷教史、前田茂人、林田直美、大津留畠、山下俊一：甲状腺乳頭がんにおけるBRAF変異と臨床病期の相関、 (第3回日本内分泌学会九州地方会、 9 ／ 20、2003) 9 、難波裕幸、大神留品、前田茂人、兼松隆之、山下俊一：甲状腺乳頭癌におけるBRAF変異（V599E）の新しい意義、Cancer Sci 94(Supple): 81, 2003 10、大津留品、難波裕幸、学佐俊郎、前田茂人、芦萍潔人、山下俊一：分子標的治療における甲状腺未分化がんの放射線治療増感効果、Cancer Sci 94(Supple): 135, 2003 11. Alex Podtcheko、大津留晶、難波裕幸、Vladimir Saenko、山下俊一：Imatinib messylate radiosensitizes p53 -mutated anaplastic thyroid cancer cell lines through induction of sustained G1 arrest followed by apoptosiss and necrosis、日本内分泌学会雑誌、79(2)：310、2003 12.難波裕幸、大津留品、前田茂人、熊谷敦史、林田直美、兼松隆之、山下俊一：甲状腺がんにおける吸引細胞診サンプルを用いたBRAF変異の術前診断の有用性、日本内分泌学会雑誌、79 (2)：311、2003