#2日日12月2日(火) Room 06 (Pacifico Yokohama Conference Center, 3F, 311+312) 2AW-06
Membrane protein targeting and quality control in organelle biogenesis Organizers：Yukio Fujiki（Kyushu University） Shunsuke Matsumoto（Kyushu University） (in the content of 2AW-06-Introduction
Yukio Fujiki (Kyushu University)
2AW-06-1
Quality control of membrane proteins at the ER Pedro Carvalho (Sir William Dunn School of Pathology, Oxford University) [9:25] 2AW-06-2 Inner nuclear membrane protein Bqt4 is degraded by a Doa10-dependent proteasomal pathway to prevent nuclear envelope deformation Toan Khanh Le, Yasuhiro Hirano, Tokuko Haraguchi, Yasushi Hiraoka  (Grad. Sch. of Front. Biosci, Osaka Univ.) 2AW-06-3 [9:40] A novel membrane protein quality control system at the endoplasmic reticulum mediated by selective lysosomal degradation Yuki Hayashi , Hidenori Ichijo  (Lab. of Cell Signaling, Grad. Sch. of Pharm. Sci., Univ. of Tokyo) ___ 2AW-06-4 [9:55] Ribosome-associated Quality Control and Mitochondrial Homeostasis Toshiaki Izawa  (Grad. Sch. of Pharmaceut. Sci., Tohoku University) --- 2AW-06-5 [10:15] Proofreading of protein mislocalization mediated by a mitochondrial AAA-ATPase Msp1 Shunsuke Matsumoto 123 , Suzuka Ono 23 , Toshiya Endo 23 ( 1 Dept. of Biosci. Biotech, Grad. Sch. of Biores. Bioenvir. Sci, Kyushu Univ, ²Fac. of Life Sci., Kyoto Sangyo Univ., 3Inst., for Protein Dynamics, Kyoto Sangyo Univ.) --- 2AW-06-6 Homeostasis of peroxisomal membrane protein assembly [10:35] Yukio Fujiki  (Medical Institute of Bioregulation, Kyushu University) 2AW-06-7
Mechanisms of membrane protein sorting Sichen Shao  (Harvard Medical School) Room 07 (Pacifico Yokohama Conference Center, 3F, 313+314) 2AW-07
Involvement of neurons-glia interactions in the brain formation during development Organizers：Fuminori Tsuruta（University of Tsukuba） Tomohiko Okazaki  (Hokkaido University) ... 2AW-07-Introduction
Fuminori Tsuruta  (University of Tsukuba) 2AW-07-1
Searching for the role of murine embryonic microglia in maternal immune activation-induced autism spectrum disorder-like behaviors Tomohiko Okazaki 12 , Ken Miyahara', Ann Ishihara', Yukiko Gotoh 1 ( 'Dept. of Mol. Biol., Grad. Sch. of Pharm. Sci. Univ. of Tokyo. 2 Lab. of Mol. Cell. Biol., IGM, Hokkaido University） [9:20] 2AW-07-2 Thrombospondin 1 Controls Circuit Specific Synapse Formation via  beta 1 Integrin Sehwon Koh', Suva Roy', Oznur Eroglu², Samuel Strader², William J. Chen², Jeremy Kay², Greg Field², Cagla Eroglu²³(¹Department of Veterinary Medicine and Surgery, University of Missouri, ²Department of Cell Biology, Duke University, ³Department of Neurobiology, Duke University) [9:39] 2AW-07-3 Regulation of synapse formation through astrocytic A2B receptor in postnatal development Eiji Shigetomi 12 , Masayoshi Tanaka ², Schuichi Koizumi 12 (†GLIA center, Univ. Yamanashi, ²Dept. Neuropharmacol. Interdiscipl. Sch. Med, Univ. Yamanashi) O MBSI 2AW-07-4 [9:58] Regulation of the fate decision between neurons and glia during corticogenesis Koji Oishi 12 , Jun Motoyama 1 , Kazunori Nakajima 2 ( ' Grad. Sch. of Brain Sci, Doshisha Univ , ² Dept. of Anat, Keio Univ. Sch. of Med.) 2AW-07-5 [10:17] Identification of neural cell types responsible for autistic-like phenotypes by Chd8 mutation Atsuki Kawamura', Yuta Katayama², Keiichi I. Nakayama², Masaaki Nishiyama' ('Dept. of Hist. Cell. Biol., Grad. Sch. of Med. Sci., Kanazawa Univ., ²Dept. of Mol. Cell. Biol., MIB, Kyushu Univ.) ... 2AW-07-6 [10:36] Cellular communications involved in the fetal alcohol spectrum syndrome Hiroshi Hasegawa  (Kobe Pharm. Univ.) 2AW-07-7 [10:55] Propagation of neuronal micronuclei regulates microglial diversity during brain development Fuminori Tsuruta', Sarasa Yano', Hikari Kubotani', Natsu Asami²( ¹ Grad. Sch. of Life and Env. Sci, Univ. of Tsukuba, ² Col. Biol. Sci. Sch. of Life and Env. Sci, Univ. of Tsukuba) 2AW-07-Conclusion [11:14] Tomohiko Okazaki (Hokkaido University) Room 08 (Pacifico Yokohama Conference Center, 3F, 315) 2AW-08 9:00-11:15 【E】 Multifaceted strategies for keeping mitochondria strong and healthy Organizers：Koji Yamano（Tokyo Metropolitan Institute of Medical Science） Ying Liu   (Peking University) 2AW-08-1 ... [9:00] Signal amplification during PINK1-Parkin-mediated mitochondrial degradation Koji Yamano (T-MIMS) 2AW-08-2 ... [9:16] Two-sided control of antiviral response by mitochondrial immunometabolic factor Yuki Hanada', Masatoshi Nomura', Yoshihiro Ogawa', Naotada Ishihara' ('Dept. of Biol. Sci., Grad. Sch. of Sci. Osaka Univ., 'Sch. of Med., Kurume Univ., 3Grad. Sch. of Med., Kyushu Univ.) --- --- 2AW-08-3 [9:32] Arf1/PI(4)KIII β -generated PI(4)P drives mitochondrial division Shun Nagashima  (Sch. of Life Sci, Tokyo Uni. of Phar. and Life Sci.) 2AW-08-4 [9:48] Mitochondrial protein heterogeneity stems from the stochastic nature of co-translational protein targeting in aging Matheus P. Viana 12 , Susanne M. Rafelski 12 , Brian M. Zid 3 , Tatsuhisa Tsuboi 24 (1 University of California Irvine, 2 Allen Institute for Cell Science, 3University of California San Diego, 'Tsinghua University Shenzhen International Graduate School) 2AW-08-5 [10:04] Epigenetic codes modulate mitochondrial stress response Ying Liu  (Peking University) 2AW-08-6 [10:27] lron loss triggers mitophagy through induction of mitochondrial ferritin Atsushi Tanaka 12 ('Res. Inst. of Med. Sci, Dept. of Med., Yamagata Univ. , ²Grad. Sch. of Med. Sci, Yamagata Univ.) 2AW-08-7 [10:43] Involvement of ubiquinone synthesis pathway in controlling mitochondrial nucleoid dynamics Soumyadip Pal , Takaya Ishihara, Naotada Ishihara  (Dept. of Biol. Sci., Grad. Sch. of Sci., Osaka Univ.) 2AW-08-8 【10:59】 Structural analysis of the mitochondrial protein import gate by near-atomic resolution snapshot and nanoscale video imaging Yuhei Araiso 1 , Akihisa Tsutsumi 2 , Kenichiro Imai 3 , Takuya Shiota 4 , Hirotatsu Imai 5 , Kana Kuzasa 1 , Noriyuki Kodera 5 , Masahide Kikkawa², Toshiya Endo 2 (†Dept. of Clin. Lab. Sci, Div. of Health Sci, Kanazawa Univ, 3Grad. Sch. of Med, Univ. of Tokyo, 3AIST, *OPTT, Univ. of Miyazaki, 5WPI-NanoLSI, Kanazawa Univ., *Fac. of Life Sci, Kyoto Sangyo Univ., 'Inst. of Protein Dynamics, Kyoto Sangyo Univ.)
Ecologically robust gut environment has personalized metabolic responses in Japanese cohort Chiharu Ishii 12 , Miyuki Suzuki 3 , Yoshiomi Soejima 4 , Morimasa Kato 5 , Masaru Tomita 16 , Shinji Fukuda 12789 (1Inst. Adv. Biosci, Keio Univ. ²Sys. Biol. Program, Grad. Sch. Media & Governance., Keio Univ. ²Shimokitazawa Hosp. 'ROHTO Pharm. Co.,Ltd., 5Yonezawa Univ. of Nutri. Sci,  Fac. of Health and Nutri, 6Dept. Env. & Info. Studies, Keio Univ. ?KISTEC, *TMRC. Tsukuba Univ., [9:55]
[10:13] 2AW-09-6 【10:31】 The nutritional basis of Drosophila-associated microbiota for larval growth Ayumi Mure', Nozomu Sakurai', Yuuki Takahashi', Masayoshi Watada', Toshihiko Katoh', Aina Gotoh', Takane Katayama', Tadashi Uemura 145 , Yukako Hattori 15 (1Grad. Sch. of Biostudies, Kyoto Univ, 2NIG, 3Grad. Sch. of Sci. and Eng, Ehime Univ, 'RCDLS, Kyoto Univ., 5AMED-CREST, 6JST FOREST) Univ. 'AMED-CREST, 'JST FOREST')
2AW-09-7 [10:49] A biogenic action of Lactobacillus plantarum SBT2227 and Bifidobacterium adolescentis SBT2786 on sleep of Drosophila Taro Ko 12 , Hiroki Murakami 2 , Syunjirou Kobayashi 12 , Azusa Kamikouchi 12 , Hiroshi Ishimoto'('Neuroscience Inst., Grad. Sch. of Sci., 
Nagoya Univ., "Milk science Resea 2AW-09-8 Dysbiosis of the human gut bacteriophage community in Multiple Sclerosis Yuya Kiguchi 12 , Daiki Takewak i23 , Masahira Hattori ', Takashi Yamamura ', Wataru Suda ' ( Waseda Univ., ² RIKEN, ³ NCNP) 2AW-09-Discussion [11:09]
2AW-10-2 ... [9:33] Reactive Cyanogen Species as a detoxificant for selenium toxicity Yasumitsu Ogra  (Lab. Toxicol. Environ. Health, Grad. Sch. Pharm. Sci, Chiba Univ.) 41 ● MBSI 2AW-10-3 [10:03] Visualization of intracellular small molecules using synchrotron radiation Mari Shimura  (Nat Cent. for Global health and Med.) 2AW-10-4 ... [10:33] ZIP13-iron axis is a new regulatory mechanism for lipolysis Ayako Fukunaka 1 , Toru Kimura ², Daisuke Saito 13 , Toshiyuki Fukada 4 , Hirotaka Watada ², Yoshio Fujitani 1 ( 1 MCR, Univ. of Gunma, ²Univ. of Kyorin, 3Grad. Sch. of Med, Univ. of Juntendo , 4Univ. of Tokushimabunri) ... 2AW-10-5 ZIP7 regulates the physiological function of ERp44 Chihiro Arai', Yuta Amagai', Kenji Inaba12 ('Grad. Sch. of Life Sci., Tohoku Univ., 2IMRAM, Tohoku Univ.) [11:03] 2AW-10-Conclusion Taiho Kambe  (Kyoto University) [11:13] Room 11 (Pacifico Yokohama Conference Center, 4F, 414+415) 2AW-11 Co-hosted by: Integrated analysis and regulation of cellular diversity 9:00-11:15 [E] Investigating cellular diversity by multi-scale single cell analyses Organizers：Yuichiro Nakajima（Tohoku University） Satoshi Takagi（Japanese Foundation for Cancer Research） 2AW-11-Introduction Yuichiro Nakajima  (Tohoku University) [9:00] 2AW-11-1
Tracing the origin of hair follicle stem cells Ritsuko Morita', Noriko Sanzen', Hiroko Sasaki', Tetsutaro Hayashi', Mana Umeda', Mika Yoshimura', Takaki Yamamoto', Tatsuo Shibata', Takaya Abe, Hiroshi Kiyonari, Tasumide Furuta', Ifoshi Nikaido 134, Hironobu Fujiwara'(RIKEN BDR, 2Mouse 2AW-11-2 [9:18] Tracing p57+ cells uncovers spatiotemporal reprogramming of differentiated cells underlying regeneration and neoplasia in the intestinal epithelium Tsunaki Higa, Yasutaka Okita, Akinobu Matsumoto, Keiichi I. Nakayama (Dept.of Mol. Cell. Biol, Med. Inst. of Bioreg, Kyushu Univ.) [9:33] 2AW-11-3 Nutrient-dependent dedifferentiation of Drosophila enteroendocrine cells dissected by single cell analyses Hiroki Nagai', Luis Augusto Eijy Nagai', Ryuichiro Nakato', Yu-ichiro Nakajima'('Grad. Sch. of Pharm. Sci, Univ. of Tokyo, ²IQB, Univ. of Tokyo) 2AW-11-4 [9:50] Integrative study of hepatic fibrosis resolution mechanisms using single-cell RNA sequencing Eiko Saijou', Tohru Itoh², Atsushi Miyajima², Luis Augusto Eijy Nagai', Ryuichiro Nakato 1 ( ¹ Lab. Computational Gen., IQB, Univ. of Tokyo, ²Lab. Cell Growth Differ., IQB, Univ. of Tokyo) )/
 [10:05] 2AW-11-5 Finding a novel lung stem cell by the established scMORN (Single-cell morphometrical, organoid-forming and RNA expression profile analysis) method. Takashi Fujimura 12 , Yasunori Enomoto', Mitsuru Morimoto' ('BDR, RIKEN, ²Otsuka pharmaceutical Co., Ltd.) 2AW-11-6 [10:20] Development of a Novel Rainbow/Barcode Dual Labeling System Using CRISPR-Cas9 Masaki Kawamata 1 , Hiroshi I Suzuki 2 , Atsushi Suzuki ' ( ' Division of Organogenesis and Regeneration, Medical Institute of Bioregulation, Kyushu University, 2Division of Molecular Oncology, Center for Neurological Diseases and Cancer, Nagoya University ( _ [10:38] 2AW-11-7 EGFR-TKI tolerant mechanisms of non-small cell lung cancer revealed by single-cell technologies Yosuke Seto', Naoya Fujita², Ryohei Katayama¹ ( ¹ Division of Experimental Chemotherapy, Cancer Chemotherapy Center, Japanese Foundation for Cancer Research, 2Center Director, Cancer Chemotherapy Center, Japanese Foundation for Cancer Research) 2AW-11-8 [10:53] Various applications of tissue-clearing method in cancer research Kei Takahashi', Kohei Miyazono³ ( 'Dept. of Chem., Fac. of Sci, Univ. of Alberta, ²Dept. of Mol. Pathol, Grad. Sch. of Med, Univ. of Tokyo) O MBSI 2AW-11-Conclusion Satoshi Takagi  (Japanese Foundation for Cancer Research) [11:13] 2AW-12
Frontiers in cellular responses on the edge of death Organizers：Kenta Moriwaki（Toho University） Toru Okamoto（Osaka University）
Control of cell death in flavivirus-infected cells Yumi Itoh', Yayoi Toki², Moyu Taniguchi², Tatsuya Suzuki', Eiichiro Fukusaki², Toru Okamoto'( ¹Research Institute for Microbial Diseases, Osaka University, ²Department of Biotechnology, Graduate School of Engineering, Osaka University) 2AW-12-2 [9:25] Identification of the novel neuro-immune interaction during viral infection in the central nervous system Riho Saito ', Tomohiko Okazaki 12 , Yukiko Gotoh ' ( ' Lab. of Mol. Biol. Fac. of Pharm. Sci., Univ. of Tokyo, ³ Lab. of Mol. Cell Biol., IGM. Hokkaido Univ.) 2AW-12-3 [9:38] The role of inflammasome to protect against bacterial infection in teleosts Jun-ichi Hikima  (Department of Biochemistry and Applied Bioscience, Faculty of Agriculture, University of Miyazaki) 2AW-12-4 [9:58] Regulation of the death receptor pathway by glycosylation: The intrinsic sweet barrier against cancer progression Kenta Moriwaki  (Dept. of Biochem, Toho Univ. Grad. Sch. of Med. ) / _ 2AW-12-5 [10:18] Alternating Arg distribution controls phase separation and toxicity of poly(PR) C9orf72 dipeptide. Kohsuke Kanekura', Chen Chen 2 , Yuhei Hayamizu 2 , Masahiko Kuroda 1 ( 'Dept. Mol. Path. Tokyo Med. Univ., 2 Dept. Mater. Sci. Eng., Sch. of Mater. Chem. Tech., Tokyo Inst. Tech.) ( 2016 ) [10:38] 2AW-12-6 Spatiotemporal analysis of cell competition by ex vivo live-imaging Asuka C. Kido 12 . Hui Liang², Shinsuke Ch í 23 , Küchiro Taniguch ², Tatsushi Igaki 12 (1 Faculty of Pharm. Sci, Kyoto Univ, 2 Grad. Sch. of Biostudies, Kyoto Univ., ³Faculty of Sci., Kyoto Univ.) s of the same anyots only. Paculty of Sel, Ryots Only.)
2AW-12-7 [10:51] Asymmetry and vulnerability of phospholipids in the plasma membrane Katsumori Segawa  (Med Res Inst, TMDU)
2AW-13  Room 13 (Pacifico Yokohama Conference Center, 4F, 418)
What is the individuality of plants Organizers：Junko Kyozuka（Tohoku University） Shinichiro Sawa（Kumamoto University）
How do plants re-construct a new life upon injury? Momoko Ikeuchi  (Fac. Sci, Niigata Univ.) 2AW-13-2 [9:30] Reprogramming of differentiated cells to stem cells triggered by DNA damage Yosuke Tamada 123 , Akihiro Imai ' , Nan Gu 12 ( ¹ Sch. Eng., Utsunomiya Univ. ³ CORE, Utsunomiya Univ., ³ REAL, Utsunomiya Univ., ' Fac. Life Sci., Hiroshima Inst. Tech.) ( _ 2AW-13-3 [9:50] Study on plant grafting Michitaka Notaguchi 123 (1Biosci. and Biotech, Nagoya Univ., ²Grad. Sch. of Bioagri Sci, Nagoya Univ., ³ITbM, Nagoya Univ.) 43 ● MBSJ 2AW-13-Break
2AW-13-4 Dispersed Individuals: vegetative propagation in a bryophyte Kimitsune Ishizaki  (Grad. Sch. Sci. Kobe Univ.)
2AW-13-5 [10:45] Genetic mosaicism in long-lived trees Akiko Satake', Sou Tomimoto', Ryosuke Imai', Eriko Sasaki', Masahiro Kasahara², Takeshi Fujino², Naoki Tani², Yoshihisa Suyama t (¹Grad. Sch. of Sci, Kyushu Univ, ²Grad. Sch. of Front. Sci, Univ. of Tokyo, ²JIRCAS, 'Grad. Sch. of Agr., Tohoku Univ.) 2AW-13-Discussion 【11:05】 ... 2AW-13-Conclusion
Shinichiro Sawa  (Kumamoto University) 2AW-14 Room 14 (Pacifico Yokohama Conference Center, 4F, 419)
Notch signaling in biological processes Organizers：Tomoko Yamakawa（Osaka University） Hiromi Shimojo（Osaka University） ...
2AW-14-Introduction Tomoko Yamakawa (Osaka University) /-- 2AW-14-1 [9:03] A neomorphic inhibitor secreted from pecanex mutant macrophages remotely suppresses Notch signaling Tomoko Yamakawa , Rin Fujii, Kenji Matsuno  (Dept. of Biol. Sci, Grad. Sch. of Sci, Osaka Univ.) ... 2AW-14-2 ... [9:18] Unicellular Notch signaling - what was it used for before multicellularity? Fuma Tanaka, Katsutoshi Aono, Naoki Yamahara, Hiroshi Suga  (Faculty of Life and Environmental Sciences, Prefectural University of Hiroshima) 2AW-14-3 [9:28] A novel role of numb prevents the embryo from antineurogenic through the inhibition of Notch signaling downstream gene, tramtrack isoform 69 (ttk69) Elzava Y Mujizah ¹ , Satoshi Kuwana ¹² , Takuma Gushiken ¹ , Kenjiroo Matsumoto ¹ 4 , Tomoko Yamakawa ¹ , Martin Baron ² , Kenji Matsuno 1 ( 1 Department of Biological Sciences, Osaka University, 2 Faculty of Life Sciences, University of Manchester, 3 Department of Basic Science. University of Tokyo (present), 'Department of Biochemistry and Molecular Biology. University of Georgia (present) ... [9:43] 2AW-14-4 Involvement of Transmembrane 2 domain containing 3 (TM2D3) into Notch signaling in vitro and in vivo Wataru Masuda', Takumi Itabashi², Toshifumi Umemiya², Rieko Ajima², Katsuya Miyake', Kazuhiko Azuma², Jun-ichi  Tamaru', Makoto  Kiso , Tomoko  Yamakawa , Puspa Das , Kenji Matsuno , Yumiko Saga , Motoo Kitagawaﾌﾟ ( 1 Dept. of Pathol, Saitama Med. Ctr., Saitama Med. Univ., ²Intl. Univ. of Health and Welfare Grad. Sch. of Health and Welfare Sci, ³Mammalian Dev. Lab., Dept. of Gene Function and Phenomics, Natl. Inst. of Genet, 'Ctr. for Basic Med. Res., Narita Campus, Intl. Univ. of Health and Welfare, 5Dept. of Mol. and Tumor Pathol, Chiba Univ. Grad. Sch. of Med., 6Dept. of Biol. Sci., Osaka Univ., 7Dept. of Biochem., Intl. Univ. of Health and Welfare Sch. of Med., 8Dept. of Basic Med. Sci. Intl. Univ. of Health and Welfare Grad. Sch. of Med.) 2AW-14-5 [9:58] Abnormalities in Notch O-glucosylation and their relationship to muscle pathology Hideyuki Takeuchi  (Dept. of Biochem., Sch. of Pharm. Sci., Univ. of Shizuoka) 2AW-14-6 [10:13] Interaction of distinct tumor cells causes interdependent tumor malignancy via Notch signaling Masato Enomoto, Daisaku Takemoto, Tatsushi Igaki  (Lab. of Genet, Grad. Sch. of Bio., Kyoto Univ.) ... 2AW-14-7 【10:23】 Notch signaling contributes the restorative effect of adipose tissue-derived mesenchymal stromal / stem cells towards impaired hepatocytes of a non-alcoholic steatohepatitis mouse model. Kosuke Ishida', Yoshio Sakai², Akihiro Seki², Kazunori Kawaguchi², Alessandro Nasti', Takashi Wada 3 , Shuichi Kaneko' ('System Biology, Grad. Sch. of Advanced Preventive Medical Sciences, Univ. of Kanazawa , ²Dept. of Gastroenterology, Hospital of Kanazawa Univ. , 3Dept. of Nephrology, Hospital of Kanazawa Univ. )第２日目  12月２日（木） 2AW-14-8 [10:33] Epidermal expression of Hes1 plays crucial role of immune response Ayumu Morioka , Mariko Moriyama, Taiki Higuchi, Hiroyuki Moriyama  (Pharm. Res. Technol. Inst., Kindai Univ.) 2AW-14-9 [10:43] Hes1 expression dynamics-dependent control of cell cycle progression Yuki Maeda 1 , Akihiro Isomura ² , Ryoichiro Kageyama ¹² ( ¹ RIKEN CBS, ² InFront, Univ. of Kyoto) 2AW-14-10 [10:58] From local synchronization by Delta-Notch signaling to global pattern formation: mathematical modeling of vertebrate segmentation clock Koichiro Uriu', Bo-Kai Liao', Andrew C. Oates', Luis G. Morelli' ('Grad. Sch. of Nat. Sci. Tech, Kanazawa Univ, ²Dept. of Aquaculture, National Taiwan Ocean Univ., 3Inst. of Bioeng., EPFL, 4Investigacion en Biomedicina de Buenos Aires) 2AW-14-Conclusion 【11:13】 Hiromi Shimojo  (Osaka University) Room 15 (Pacifico Yokohama Conference Center, 5F, 501) 2AW-15 Toward an understanding of complex biochemical systems from a phase separated compartment, “nucleolus" 9:00-11:15 【E】 Organizers：Satoru Ide   (National Institute of Genetics) Noriko Saitoh（Japanese Foundation for Cancer Research） 2AW-15-Introduction [9:00] --- Satoru Ide  (National Institute of Genetics) 2AW-15-1 [9:03] Phase separation of the subnucleolar compartments, the fibrillar centers Satoru Ide 12 , Yasuto Murayama 23 , Ryosuke Imai 13 , Hiroko Ochi', Kazuhiro Maeshima 12 ( ' Dept. of Chromosome Sci. Natl. Inst. of Genet., ²Sch. of Life Sci., Grad. Univ. for Advanced Studies (SOKENDAI), ³Cent. for Front. Res., Natl. Inst. of Genet.) 2AW-15-2 [9:23] SLERT maintains nucleolar liquidity to facilitate Pol I transcription Man Wu, Guang Xu, Chong Han, Jiaquan Liu, Ling-Ling Chen  (CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences) ... [9:53] 2AW-15-3 The nucleolar protein NOL11 regulates mitosis directly, and indirectly through regulating the nucleolar integrity during interphase. Kazashi Kato', Yuki Hayashi 12 , Akiko Fujimura 1 , Toru Hirota 2 , Keiji Kimura 12 (1 Gad. Sch. of Life and Env. Sci. Univ of Tsukuba. 2 TARA, Univ of Tsukuba, ³Div. of Exp. Path., Cancer Inst. of JFCR) 2AW-15-4 [10:13] Analysis of stability and methylation status of the mammalian ribosomal RNA gene cluster using Nanopore long-read sequencer Yutaro Hori', Akira Shimamoto², Takehiko Kobayashi 1 († IQB, Univ. of Tokyo, ² Dept. of Pharm , Sanyo-Onoda Univ.) 2AW-15-5 [10:33] Structural alterations in ribosomal DNA under nucleolar stress Keiko Kawauchi', Takeru Torii', Hisae Karimata Tateishi², Naoki Sugimoto², Takahito Nishikata¹, Daisuke Miyoshi'(¹FIRST, Konan Univ., ²FIBER, Konan Univ.) --- 2AW-15-6 [10:53] RPL5 maintains spatial organization of the ribosomal DNA arrays through regulation of biophysical properties of the nucleolus Noriko Saitoh ', Haruka Matsumori ², Kenji Watanabe ¹, Hiroaki Tachiwana ¹, Yuma Ito ³, Kumiko Sakata-Sogawa ³, Makio Tokunaga ³, Akinori Awatsu 4 , Mitsuyoshi Nakao 2 ( ¹ The Cancer Inst. JFCR, ² Kumamoto Univ. 3 Tokyo Inst. Tech. ' Hiroshima Univ.) 2AW-15-Conclusion Noriko Saitoh  (Japanese Foundation for Cancer Research) [11:13] 2AW-18 Room 18 (Pacifico Yokohama Conference Center, 5F, 511+512) Co-hosted by: Genome modality: understanding physical properties of the genome 9:00-11:15 [E] Genome modality: understanding physical properties of the genome Organizers：Tetsuya Yamamoto（Hokkaido University） Ikuko Motoike（Tohoku University） --- 2AW-18-1 [9:00] The role of cohesin and its loader in transcriptional regulation Katsuhiko Shirahige, Toyonori Sakata, Atsunori Yoshimura, Shoin Tei, Katsunori Fujiki, Ryuichiro Nakato, Takashi Sutani, Masashige Bando  (IQB, The Univ. of Tokyo) Bando (IQD, The Univ. of Tokyo) 2AW-18-2 [9:18] Modality of mitotic chromosomes Tatsuya Hirano (RIKEN) --- 2AW-18-3 ... [9:36] Computational approach to structural dynamics and functions of SMC proteins Shoji Takada  (Dept of Biophys. Grad. Sch. of Sci. Kyoto Univ.) 2AW-18-4 ... [9:54] Nucleosome repositioning dynamics upon collision with a translocase Tsuyoshi Terakawa  (Dept. of Biol. Sci., Grad. Sch. of Sci., Kyoto Univ.) 2AW-18-5 ... [10:12] Biochemical and structural characterizations of the chromosomal cohesin complex Yasuto Murayama , Yumiko Kurokawa  (Natl. Inst. of Genet.) 2AW-18-6 ... [10:30] Cohesin constrains local chromatin motion through chromatin domain formation Shiori Iida 12 , Kazuhiro Maeshima 12 ('Genome Dynamics Lab, Natl. Inst. of Genet., ²Dept. of Genet., Sch. of Life Sci., SOKENDAI) --- 2AW-18-7 [10:45] Mechanism on transposon expression regulated by histone variant dynamics Akihisa Osakabe 12 , Chikae Yamasaki 1 , Yuriko Tanaka 1 , Bhagyshree Jamge 3 , Zdravko Lorkovic 3 , Frédéric Berger 3 , Tetsuji Kakutani ' (†Dept. of Biol. Sci, Grad. Sch. of Sci, Univ. of Tokyo, ²JST PRESTO, ²Gregor Mendel Institute, VBC) 2AW-18-8 [11:00] Domain and functional analyses of the DNA quadruplex binding of human ORC subunits Shou Waga, Chiho Shioda, Akane Tanonaka, Wakana Matsumoto, Haruka  Horinouchi  (Dept. of Chem. Biol. Sci, Faculty of Sci, Japan Women's Univ.) 2PW-02 Room 02 (Pacifico Yokohama Conference Center, 3F, 301)
Scientific verification of biological effects of aerosols and droplets in the air Organizers：Tatsuya Mimura（Teikyo University） Yasuhiro Yoshida（University of Occupational and Environmental Health） 2PW-02-Introduction
Tatsuya Mimura (Teikyo University) 2PW-02-1 --- 【15:50】 Differences in the Cellular Expression Level of Proteins Associated with COVID-19 Induced by Exposure to Various Particulate Matters Hirohisa Takano 12 , Raga Ishikawa 1 ( ¹ Grad. Sch. of Eng., Kyoto Univ., ³ Grad. Sch. of Global Environ. Studies, Kyoto Univ.) 2PW-02-2 [16:03] Droplets-derived aerosol generation during conversation and mask protection Tatsuya Mimura , Atsushi Mizota  (Dept. Ophthalmology, Teikyo Univ.) ... 2PW-02-3 ... [16:16] Finding Flavor and fragrance compositions to inhibit binding of Virus RBD with human ACE2 Akira Yamauchi', Yasumitsu Nishimura', Kenta Nomiyama', Aya Morihara', Ayasa Kamezaki', Mika Igarashi', Yusuke Yorifuji', Yukino Sato 3, Futoshi Kuribayashi' ( 'Dept. of Biochem, Kawasaki Medical School, ²Dept. of Hygiene, Kawasaki Medical School, ³SHIONO KORYO KAISHA, LTD.) O MBSI 2PW-02-4 [16:25] Induction of allergic airway inflammation by fungi isolated from Asian dust aerosol Takamichi Ichinose  (Dept. of Health. Sci., Oita Univ. of Nursing) 2PW-02-5 [16:38] Environmental factor such as Virus infection and exhaust gas may play an important role of pathogenesis of ocular allergy Hiroshi Fujishima  (Dept. of Ophthalmology, Tsurumi Univ. School of Dental Medicine) 2PW-02-6 [16:51] Particle-containing personal care products exacerbate allergic responses Akiko Honda 12 , Hirohisa Takano 12 ('Grad. School. of Grobal Environ. Studies. Kyoto Univ., ²Grad. Sch. of Eng., Kyoto Univ.) 2PW-02-7 [17:04] E3 ligase Skp2 progresses bleomycin-induced pulmonary fibrosis Kyoko Kitagawa 12 , Masashi Mikamo , Mayumi Tsuji , Masatoshi Kitagawa 2 ( 1 Dept. of Environ. Health, Univ. of Occu. Environ. Health, ²Dept. Mol. Biol., Hamamatsu Univ. Sch. of Med.) ( _ 2PW-02-8 [17:17] Effects of formaldehyde stress on human health Jun Nakamura  (Lab. Animal Sci, Grad. Sch. of Life and Environ. Biosci, Osaka Pref. Univ.) 2PW-02-9 [17:30] Cellular senescence and inflammaging in the splenocytes of old mice exposed to irradiation at a young age Yasuhiro Yoshida  (University of Occupational and Environmental Health) --- [17:42] 2PW-02-10 Establishment of novel protein interaction assays between Sin3b and REST using surface plasmon resonance and time- resolved 4 fluorescence energy transfer. Masamitsu Harada 1 , Riho Kurata 2 , Yasuhiro Yoshida 2 , Tomo Yonezawa 4 ( 'Indep. Scholar, 2 Edu. and Res. Center for Pharm. Sci, Osaka Univ. of Med. Pharm. Sci, 3Depart. of Immunol. and Parasitol, Univ. of Occup. and Environ. Health, 'Gene Res. Center, Grad. Sch. of Biomed. Sci, Nagasaki Univ.) 2PW-02-Conclusion [17:55] Yasuhiro Yoshida  (University of Occupational and Environmental Health) 2PW-03  Room 03 (Pacifico Yokohama Conference Center, 3F, 302) Co-hosted by: Japan Society for Biomedical Gerontology 15:45-18:00【E】 Inflammaging, taking lessons from history Organizers：Mitsuo Maruyama（National Center for Geriatrics and Gerontology） Takahiko Shimizu（National Center for Geriatrics and Gerontology） 2PW-03-Introduction [15:45] Takahiko Shimizu  (National Center for Geriatrics and Gerontology) 2PW-03-1
Senoinflammation as the underlying molecular mechanism of aging Hae Young Chung  (Dept. of Pharm., Coll. of Pharm., Pusan Nat. Univ.) 2PW-03-2 [16:16] Molecular mechanism underlying cell death-triggered chronic inflammation in the metabolic syndrome Takayoshi Suganami  (Nagoya University) --- 2PW-03-3 [16:46] Rejuvenation of embryos from aging mice by suppression of a SASP factor, CXCL5-CXCR2 signaling Kazuhiro Kawamura  (Dept. of OB/GYN, Sch. of Med., Univ. of IUHW) 2PW-03-4 [17:16] Comparison of the fertility of tumor suppressor gene-deficient C57BL/6 mouse strains reveals stable reproductive aging and novel pleiotropic gene Masaoki Kohzaki', Akira Ootsuyama², Toshiyuki Umata², Ryuji Okazaki' ('Dep. of Radiobiol. Hyg. Manage., Inst. of Ind. Ecol. Sci., Univ. of Occup. Environ. Health, ²Dep. of Radiat. Biol. Health, Sch. of Med, Univ. of Occup. Environ. Health, ²Radioisotope Res. Ctr., Facil. for Edu. Res. Spt. Univ. of Occup. Environ. Health） [17:29] 2PW-03-5 Microglia's multiple immune functions in neurodegenerative disease Michael T. Heneka ¹ . Hannah Scheiblich¹ , Melki Ronald² (¹University of Bonn, ²University of Paris) O MBSI第２日目  12月２日（木） 2PW-03-Conclusion Mitsuo Maruyama  (National center for Geriatrics and Gerontology) [17:59]
種の個性を生み出す原動力とは何か？
2PW-04-1
ショウジョウバエ近縁種群の比較解析から迫る全身性およびクロマチン制御を介した栄養環境への適応機構渡辺佳織¹上村匡¹²³服部佑佳子¹ (¹京大・院生命科学, ³京都大学大学院生命科学研究科附属生命動態研究センタ, ³AMED-CREST, 4 JST創発) 2PW-04-2 [16:03] Vigna属野生種が魅せる耐塩性進化の多様性内藤健(農研樓橋) 2PW-04-3
Keap1のユビキチン化活性の「減弱」は動物の陸上進出に必要な分子進化である弓本佳苗¹高橋大輔².中山敬一¹ (¹九大・生医研・分子医科学, ²九大・院薬・蛋白質創薬学) 2PW-04-4
線虫近縁種比較から解き明かす生殖システム進化杉本重砂子(東北大・生命科学) 2PW-04-5 [16:54]クマムシ固有の乾燥耐性タンパク質による脱水ストレスに応答した可逆的な細胞骨格様線雑/ゲルの形成田中彬賀'中野智美' ,渡邊館斗' ,増田和後'鎌田周一'秦裕子'知念拓夫' ,北川大樹' ,尾山大明'柳澤英雄'國枝武和' (東大・院理・生物科学, *東大・院総・広域科学, *東大・医科研・疾患プロテオミクス, '東大・院薬・生理化学) 2PW-04-6 【17:11】大脳皮質進化をもたらした、ヒト特異的NOTCH2NL遺伝子によるNotch受容体とリガンドのバランス調節機構鈴木郁夫(東大・院理・生物科学) 2PW-04-7マウス目特異的なリピート関連ノンコーディングRNA 4.5SHによる生体制御中川真一(北大・薬学研究院)
2PW-04-総合計論[17:45] 2PW-08
15:45-18:00【E】 Cell division in diverse contexts Organizers：Masatoshi Hara（Osaka University） Tomomi Kiyomitsu（OIST）
[15:48] Moe Yamada , Shu Yao Leong, Tomoya Edzuka, Gohta Goshima (Div. of Biol. Sci., Dept. of Sci., Nagoya Univ.) 2PW-08-2 [16:06] How dynein-NuMA complexes maintain mitotic spindle-pole focusing in human cells Susan Boerner ¹ , Momoko Nishina ² , Masako Okumura ² , Tomomi Kiyomitsu ¹³ (¹ OIST, ²Grad. Sch. of Sci, Nagoya Univ.) 2PW-08-3 [16:21] Pins suppresses abnormal cell-fate reprogramming during wing regeneration in Drosophila Yuichiro Nakajima¹²(¹ Lab of Genetics. Grad. Sch. of Pharm., Univ. of Tokyo, ²FRIS, Tohoku Univ.) O MBSI 2PW-08-4 【16:39】 Distinct types of stem cell divisions determine organ regeneration and aging in hair follicles Hiroyuki Matsumura', Nan Liu', Daisuke Nanba', Ichinose Shizuko', Takada Aki', Sotaro Kurata', Hironobu Morinaga', Yasuaki Mohri', Adele  De Arcangelis', Shigeo Ohno', Emi  K Nishimura15 ('Dept. of Stem Cell Biology, Med. Research Inst. Tokyo Med. and Dent. Univ. 3Research Cent. for Med. and Dent. Sciences, Tokyo Med. and Dent. Univ. 3Beppu Garden-Hill Clinic, Kurata Clinic, 'Instite de Genetique et de Biologie Moleculaire et Cellulaire(IGBMC) , Dept. of Develop. and Stem Cells, "Dept. of Mol. Biol, Yokohama City Univ. School of Med., "Div. of Aging and Regenerative Biol., Inst. of Med. Science, Univ. of Tokyo) 2PW-08-5 [16:54] The plastic regulation of chromosome segregation in cancer stem cells Minji Jo', Oltea Sampetrean², Tetsuya Negoto¹, Utako Kato¹, Hideyuki Saya², Toru Hirota¹(¹Div. of Exp. Path, Cancer Inst., JFCR , ²Gene Regulation, IAMR, Keio Univ. Sch. Med) . . . 2PW-08-6 [17:12] Growth and division mode plasticity is dependent on cell density in marine-derived black yeasts Gohta Goshima  (Marine Bio lab, Nagoya Univ.) 2PW-08-7 [17:27] Analysis of the mechanism for meiotic cohesion-mediated formation of higher-order chromosomal structures enabling reductional segregation at meiosis l Takeshi Sakuno', Sanki Tasshiro², Osamu Iwasaki², Hideki Tanizawa², Tokuko Haraguchi', Ken-ichi Noma 23 , Yasushi Hiraoaka'('Grad. Sch. of FBS, Osaka Univ., ²Insti, Mol. Biol, Univ. Oregon, ³Insti, Genet. Med., Hokkaido Univ.) 2PW-08-8 [17:42] Kinetochore dynamics in the early embryonic development Masatoshi Hara', Masakazu Hashimoto', Mami Nakagawa', Hiroshi Sasaki', Toshihiko Fujimori', Tatsuo Fukagawa'('FBS, Osaka Univ., ²Div. of Embryology, NIBB) ... 2PW-08-Conclusion [17:57] Masatoshi Hara  (Osaka University) 2PW-09 Room 09 (Pacifico Yokohama Conference Center, 4F, 411+412) 15:45-18:00【E】 What is life in a microbe? Organizers：Shogo Ozaki（Kyushu University） Setsu Kato（Hiroshima University） 2PW-09-1 ... [15:45] Analysis of the chromosomal replication mechanism in the eubacterium Caulobacter crescentus Shogo Ozaki , Tsutomu Katayama  (Dept. of Mol. Biol. Grad. Sch. of Pharm. Sci., Kyushu Univ.) 2PW-09-2 [15:56] Structural and functional analysis of the interaction between family D-DNA polymerase and CMG-like helicase in the replisome of Thermococcus kodakarensis Keisuke Oki ¹ , Mariko Nagata ¹ , Takeshi Yamagami ¹ , Tomoyuki Numata ¹ , Sonoko Ishino ¹ , Takuji Oyama ² , Yoshizumi Ishino 1 ('Department of Bioscience and Biotechnology, Graduate School of Bioresource and Bioenvironmental Sciences, Kyushu University, ²Faculty of Life and Environmental Sciences, University of Yamanashi) (2015) [16:07] Nucleoid segregation and the proliferation of the bacterial cell Koichiro Akiyama , Koichi Yano, Hironori Niki  (NIG) ... 2PW-09-4 [16:25] Functional analysis of the single-domain RelA/SpoT homolog proteins which inhibit bacterial growth. Tatsuaki Kurata', Gemma Atkinson', Vasili  Hauryliuk 123 (1Dept. of Exp. Med. Sci, Lund Univ, 2 Inst. of Tech, Univ. of Tartu, 3 MIMS, Umea Univ.) 2PW-09-5 Life and death of Escherichia coli cells in batch culture Setsu Kato  (Grad. Sch. Integr. Sci. Life, Hiroshima Univ.) [16:36] 2PW-09-6 [16:47] Adaptation to genetic modification in Escherichia coli Miki Umetani 12 . Yuta Koganezawa', Moritoshi Sato 234 , Yuichi Wakamoto 124 (1Dept. of Basic Sci., Grad. Sch. of Arts and Sci., Univ. of Tokyo, ²Res. Ctr for Complex Systems Biol, Univ. of Tokyo, ³Dept. of Life Sci, Grad. Sch. of Arts and Sci, Univ. of Tokyo, 'UBI, Univ. of Tokyo)第２日目  12月２日（木） 2PW-09-7 [17:05] A constructive approach to elucidate the principle determining the living state of microbes Kei FUJIWARA  (Dept. Biosci. Info, Keio Univ) 2PW-09-8 ... [17:23] Modeling a whole bacterial cell from a genomic sequence Kazunari Kaizu 12 , Kozo Nishida ¹, Eliott Jacopin ³, Koichi Takahashi ' ( ¹ RIKEN BDR, ² PRESTO JST, ³ Grad. Sch. of Front. Biosciences, Osaka Univ.) 2PW-09-9 [17:41] Survival of microbes in space and the search for life on Mars Akihiko Yamagishi  (School. Life Scie., Tokyo Univ. Pharm. Life Scie.) 2PW-09-Conclusion Shogo Ozaki ' , Setsu Kato 2 ( ¹ Kyushu University, ² Hiroshima University) [17:59] Room 12 (Pacifico Yokohama Conference Center, 4F, 416+417) 2PW-12 15:45-18:00 [E] Interactions between neural cells and immigrant cells during the development and aging in the brain Organizers：Hidenori Tabata（Institute for Developmental Research, Aichi Developmental Disability Center） Yuki Hattori（Nagoya University） ...
[16:39] [17:06] [17:33] Brain immunity established and maintained by primitive macrophages and neurodegenerative diseases Kazuyuki Takata  (Div. Integ. Pharm. Sci., Kyoto Pharm. Univ.) 2PW-13  Room 13 (Pacifico Yokohama Conference Center, 4F, 418) TAISHITSU Science from the viewpoint of Artificial Energy-Saving TAISHITSU models 15:45-18:00 [E] Organizers：Takahiro Nemoto（Nippon Medical School） Tomoko Kawai（National Center for Child Health and Development） 2PW-13-1 [15:45] The Thrifty TAISHITSU, which was acquired due to embryonic malnutrition Takahiro Nemoto  (Dept. Physiology, Nippon Medical School) ___ 2PW-13-2 --- [16:12] Maternal undernutrition during pregnancy programs risk of nonalcoholic fatty liver disease (NAFLD): A study of mice animal model Hiroaki Itoh  (Hamamatsu University School of Medicine) 2PW-13-3 [16:39] Imprinted genes, energy-saving, and early embryos Shuntaro Ikeda  (Grad. Sch. of Agr., Kyoto Univ.) ... 2PW-13-4 --- [17:06] The elucidation of the role of the nutritional environment during fetal life using the human iPS cell differentiation system Nobuaki Shiraki  (Sch. of Life Sci. and Tech., Tokyo Tech)
O MBSI 2PW-13-5 [17:33] Identification of epigenetic changes at birth in human that perinatal environment factors associate Tomoko Kawai ', Tomoka Kato ', Kohei Kashima 2, Yoshifumi Kasuga 3, Kei Miyakoshi 3, Reiko Horikawa 4, Kenichiro Hata 1 ('Dept. of MFB, NCCHD, ²Dept. of Ped., Sch. of Med., Univ. of Tokyo, ³Dept. of OBGY, Sch. of Med., Keio Univ., 'Div. of Endo., NCCHD)
Extracellular vesicles for liquid biopsy
森雄太郎12.岸議司².市村陸治². Bonventre Joseph²( ¹ハーバード大・医・プリガムアンドウィメンズ航院・内科・腎臓部門. ²東京医科衛科大・院医衛・腎臓内科学, ³徳大・院医歯薬・腎臓内科学) O MBSI第10会場（パシフィコ横浜会議センター 4F「413」） 2PWS1-10構造生命科学の新展開-見えないモノを見ようとして電子顕微鏡を覗き込んだ-オーガナイザー：西増弘志(東京大学)西澤知宏(横浜市立大学)
Structure of a Dicer-2-R2D2 heterodimer bound to a small RNA duplex Sonomi Yamaguchi', Masahiro Naganuma², Tomohiro Nishizawa², Yukihide Tomari', Hiroshi Nishimasu², Osamu Nureki'(¹ Graduate School of Science, Univ. of Tokyo, ²RIKEN Center for Biosystem Dynamics Research, ³Graduate School of Medical Life Science, YCU, ¹Institute for Quantitative Biosciences, Univ of Tokyo, 5Research Center for Advanced Science and Technology, Univ. of Tokyo) 2PWS1-10-2 [16:05]脂質二重膜に埋め込まれた膜タンパク質のCryo-EM構造解析李勇燦(横浜市大・院・生命医科学) 2PWS1-10-3
ヒト由来MrgD受容体の活性化機構の構造学的洞察鈴木翔大,飯田桃子,飯明洋子,田中康太郎,川本晃大,加藤貴之,大嶋筒典'' ('名大・院創薬科学, '名大・理・生命科学, '名大・細胞生理学研究センター , *一般社団法人バイオ産業情報化コンソーシアム, s販大・蛋白研) 2PWS1-10-4 [16:38]細胞膜リン脂質スクランブラーゼであるヒトXkr8-Basigin複合体の立体構造機木禁晴'.金井陸太'.包明久'.成田宏隆'.大西映里子'.西野精平'.宮崎拓也'.馬場威'.小迫英尊'.中川敦史'.吉川雅美'.豊島近².長田金一1 '阪大・免フロ・免竣生化 ²東大・定量研・醸蛋白 ²東大・院医・生体構造. '阪大・蛋白研・超分子, '傲大・藤井節廊記念・編題情報. 6中外・研究本部) 2PWS1-10-5 [16:53] Structural basis for channel conduction in the pump-like channelrhodopsin ChRmine Koichiro Kishi', Yoon Seok Kim², Masahiro Fukuda', Tsukasa Kusakizako², Elina Thadhani', Eamon Byrne², Joseph Paggi', Charu Ramakrishnan 5 , Toshiki Matsui', Keitaro Yamashita 6 , Takashi Nagata 7 , Masae Konno 7 , Peter Wang 7 , Masatoshi Inoue 2 , Tyler Benster 7 , Tomoko Uemura 8, Kehong Liu 8, Mikihiro Shibata 9, Norimichi Nomura 8, So Iwata 8, Osamu Nureki 3, Ron Dror 4, Keiichi Inoue 7, Karl Deisseroth ², Hideaki Kato ' (¹Komaba Inst. for Sci, UTokyo, ²Dept. of Bioengineering. Stanford, ²Dept. of Biol. Sci, UTokyo, ' Dept. of CS, Stanford, 5 CNC, Stanford, 6 MRC, Cambridge, 7 Inst. for Solid State Phys. UTokyo, 5 Dept. of Cell Biol. Kyoto U., 9 WPI-NanoLSI, Kanazawa U.) 2PWS1-10-Conclusion西澤知宏(横浜市立大学) [17:13] 2PWS1-11第11会場（パシフィコ横浜会議センター 4F「414+415」）
神経生物学的プロテオスタシスについて考えるオーガナイザー：若月修二（国立精神・神経医療研究センター）松本弦(長崎大学) 2PWS1-11-1
酸化ストレスを神経変性に変換する仕組み若月修二1大野南磐12 ,荒木鉱之1 1国立精神神経七・神経研・疾病五部, 5東京農工大・院工・生命工1 2PWS1-11-2 [16:02] LUBACユビキチンリガーゼと直鎖状ユビキチン鎖が筋萎縮性側索硬化症関連タンバク質TDP-43の細胞質内凝集形成を促進する寺脇正閘',張強',及川大輔',林邦忠',布村一人',駒川晋輔',臼杵克之助',德永文稔'('大阪市大・院医・分子病態学, '欧大・院薬・附厩創薬センター・橋造展開ユニット, 3大阪市大・院理・有機反応化学) 2PWS1-11-3 [16:17] Derlin familyによる小胞体プロテオスタシスを介した脳の発達と機能維持機構村尾直哉,杉山崇史12西頭英起1 (宮崎大・医・機能生化学, ²宮崎大・医・脳神経内科) 2PWS1-11-4 [16:32]遺伝性パーキンソン病関連タンパク質DJ-1のアンフォールディングがミトコンドリアへの取り込みとミトコンドリア内分解を引き起こす松田憲之(都医学研・基礎医科学) 2PWS1-11-5 [16:57]アグリファジー制御による線維化タウ凝集体の細胞内分解松本弦(長崎大院・医衛薬学(医)) 53 O MBSI 2PWS1-15 Room 15 (Pacifico Yokohama Conference Center, 5F, 501)
RNA and phase separation: an inseparable relationship Organizers：Hiroya Yamazaki（The University of Tokyo） Tomohiro Yamazaki（Osaka University） ... 2PWS1-15-Introduction
Hiroya Yamazaki (The University of Tokyo) )
. 2PWS1-15-1 [15:49] Characterization of the DEAD-box RNA helicase Vasa in LLPS-mediated formation of germ granule, which is the piRNA biogenesis center in ovarian germ cells Hiroya  Yamazaki, Kazumichi M. Nishida, Ryo Murakami, Shogo Kuriyama, Asako Kajiya, Mikiko C. Siomi  (Dept. of Biol. Sci, Grad. Sch. of Sci, Univ. of Tokyo) 【16:05】 C9ORF72 dipeptide repeat proteins disrupt formation of GEM bodies and induce aberrant accumulation of survival of motor neuron protein Hitomi Tsuiji', Yuma Kato', Minnie Yokogawa', Ikuma Nakagawa', Kazunari Onodera', Hideyuki Okano', Haruhisa Inoue 456 Mitsuharu Hattori', Yohei Okada 2 ( 'Dept. of Biomed. Sci., Grad. Sch. of Pharmaceutic. Sci., Nagoya City Univ., 'Sch. of Med., Aichi Med. Univ., ³Sch. of Med., Keio. Univ. , ⁴CiRA, Kyoto Univ., ⁵RIKEN BRC, ⁶RIKEN AIP) --- 2PWS1-15-3 [16:21] RNAs as scaffolds of biomolecular condensates: from LLPS to micellization Tomohiro Yamazaki 1 , Tetsuya Yamamoto 2 , Sylvie Souquere 3 , Shinichi Nakagawa 4 , Gerard Pierron 3 , Tetsuro Hirose 3 ('Grad. Sch. of Front. Biosci. Osaka Univ., ²ICReDD, Hokkaido Univ., ³CNRS, Inst Gustave Roussy, 'Fac. of Pharm, Sci., Hokkaido Univ.) 2PWS1-15-4 [16:37] A new method for gene expression analysis confined to small regions of interest Ryuichi Kimura', Mizuki Honda', Akihito Harada', Kazumitsu Maehara', Kaori Tanaka', Yasuyuki Ohkawa', Shinya Oki'('Department of Drug Discovery Medicine, Kyoto University Graduate School of Medicine, ²Division of Transcriptomics, Medical Institute of Bioregulation, Kyushu University)
2PWS1-15-5 [16:53] Phase separation in plant miRNA processing Yijun Qi 12 (1 Center for Plant Biology, School of Life Sciences, Tsinghua University, 2 Tsinghua University-Peking University Joint Center for Life Sciences, Tsinghua University) ... --- 2PWS1-15-Conclusion Tomohiro Yamazaki (Osaka University) [17:13] 2PWS1-18あなたの知らないSLFN11の世界第18会場（パシフィコ横浜会議センター 5F「511+512」） 15:45-17:15 【J/E】オーガナイザー：村井純子(慶應義塾大学)高田穣(京都大学) 2PWS1-18-Introduction村井純子(慶應義塾大学)
2PWS1-18-1
複製ストレス制御因子SLFN11の多彩な機能〜複製、転写、クロマチン構造〜そして臨床応用へ村井純子(慶應義塾大学・先端生命科学研究所) 2PWS1-18-2 [16:10] SLFN11とSLFNファミリー機能の統一的理解を目指して高田穣, Alvi Erin',小川みのり,藤木陽子,岡本祐介, Canela Andres 12 ,盛月幾子,本安峰( '京大・院生命・放生研, '京大・白眉センター) ... 2PWS1-18-3 [16:30] SLFN11の小胞体ストレスと異常タンパク応答抑制機能とSLFN11陰性腫瘍に対する新たな治療戦略への期待村井康久123. Ukhyun Jo²,村井純子4 , Lisa M. Jenkins², Shar-Yin N. Huang², Sirisha Chakka², Lu Chen², Ken Cheng²,標産裕丈  1福田黄作², Naoko Takebe², Yves Pommier²(弘大・院医・地域救急医療学,弘大・院医・消化器血液内科学, ²米国・国立衛生研究所・がん研究所, 4慶応大・先端生命科学研究所) ... [16:50] 2PWS1-18-4炎症性腸疾患におけるSLFN11の役割土屋師一郎(筑波大学) O MBSI第２日目  12月２日（木）
服部高子',中川武弥',米田光宏',中川香をり',林田広美',武田弘资',伊藤敬'('長大・院医衛薬・生化学, ²長大・院医衛薬・編胞制御学) O MBSI 2PWS2-06-3 [17:51] KDM5Aは骨髄腫細胞においてRNAポリメラーゼIIリン酸化を制御し、MYC駆動性の転写を促進する大口裕人¹ , Paul Park², Tingjian Wang², Berkley Gryder²,扇居大輪²,倉田啓史², Xiaofeng Zhang², Deyao Li², Chengkui Pei²,増田察, Catrine Johansson², Virangika Wimalasena², Yong Kim²,日野信次朗²,臼杵慎吾²,河野和10 , Mehmet Samur², Yu-Tzu Tai², Nikhil Munshi ,松岡雅雄,大槻純男,中居光善,南敬" Shannon Lauberth 12 , Javed Khan 3 , Udo Oppermann 7 , Adam Durbin 13 Kenneth Anderson 5,秀烏輝, Jun Qi 2 (熊大・IRDA・疾患エピゲノム5ダナファーバー瓶研・がん生物, 3 NIH・NCI・遺伝学, 4ケースウエスタンリザープ大・医・遺伝学. 5ナファーバー瓶研・医がん,熊大・院生命科学・敵生物薬学,オックスフォード大　整外,熊大・
発生研・細胞医学,熊大・発生研・リエゾンラボ, "熊大・医・血内, "熊大・IRDA・分子血管, "カリフォルニア大・生物科学, "セントジュード小児研病院・分子がん) 2PWS2-06-4 [17:59]変異p53のgain of functionによるSREBP依存的コレステロール合成経路の制御と乳がん悪性化形質田中知明(千葉大・院医・分子病態) 2PWS2-06-5 [18:11]クロマチン作用因子ポリコーム群複合体のDNA修復機能による癌抑制磯野協一1木村弥生2 ,公文麻美1遠藤高帆1古関明彦3 1和医大・医・動物実験施設, 2横浜医大・先端医, 3理研・IMS・免疫器官形成, *理研・IMS・統合ゲノミクス） 2PWS2-06-6 [18:19] MLL遺伝子変異による大腸癌進展のメカニズム解析およびMLL複合体内タンパク質問相互作用を標的とする創薬米田光宏,中川武弥,服部高子,伊藤敬(長大・院・医衛薬・生化学) 2PWS2-06-7 [18:27]エピジェネティック制御因子は異常メチル化に抵抗性だが、SETD6は胃がんにおいてメチル化サイレンシングされる竹島秀幸,西山和宏,牛島後和(国がん研セ・研・エピゲノム) 2PWS2-06-8 --- [18:35]ミトコンドリア呼吸鎖超複合体を介する代謝リモデリングとがん増殖池田和博',堀江公仁子',井上聡¹²('埼玉医大・医・ゲノム応用医, ²都健康長寿医療セ・研究所・システム加齢医) 2PWS2-06-9 [18:47]多様なストレスに対峙するゲノムストレス応答蛋白質複合体の揺らぎ井倉繋げ古谷寛治²白木琢磨²井倉正枝² (京大・院生命・高次生命科学・放生研・クロマチン動態制御学, ²京大・院生命・高次生命科学・放生研・ゲノム維持機構学, 3近畿大学生物理工学部) 2PWS2-06-Conclusion井上聡(東京都健康長寿医療センター研究所) [18:59]第07会場(パシフィコ横浜会議センター 3F「313+314」) 2PWS2-07共催：日本メイラード学会17:30-19:00 [J]免疫反応や加齢性疾患におけるグリケーションの役割オーガナイザー：三五一憲(東京都医学総合研究所)大矢友子(修文大学) 2PWS2-07-Introduction三五一憲(東京都医学総合研究所)
2PWS2-07-1
生体におけるグリケーションと自然免疫応答近澤未夢(名城大学農学部) 2PWS2-07-2 [17:53]骨芽細胞内の終末糖化産物の蓄積は小胞体ストレスを介してapoptosisを誘導する鈴木隆介12,藤原章雄,斎藤犬,荒川翔太郎,白河潤一,山中幹宏,孟原義弘,永井竜児² (慈恵医大・整形, *楽海大・農学部, ³熊大・細胞病理） 2PWS2-07-3 [18:15]セレノグルタチオンの添加がもたらすグリオキサラーゼ1発現抑制細胞の糖化・酸化ストレス抵抗性の回復効果金森番子127 ,高橋沙和,大启早葵,下平伸吾,岩岡道夫( '東海大・工・生命化学, '東海大・先進生命科学研究所, '東海大・院・工学研究・応用理化学, '東海大・理・化学) 2PWS2-07-4 [18:37]糖尿病性神経障害の病態におけるAGEs-RAGEシグナルとマクロファージ極性変化について選野井祥',三五一憲',水上浩哉'('弘前大・院医・分子病態病理, '東京都医学研・糖尿病性神経障害プロジェクト)