DIGITALPATHAPERIO GT 450OLOGYSLIDE SCANNER
BROCHURE

Fast forward
to nextgeneration imaging
Integrating innovation andautomation for research labs

For research use only. Not for use in diagnostic
procedures.
*International patent families including patent applications
and granted patents.

More than 30
Patents SMARTER*DIGIT

High resolution

ALPAT

Image quality

Confident Diagnosis
Limited rescans
Faster turnaround time Integrated work-flow Craftsmanship State-of-the-art Fast viewing speeds

Next generation imaging for Scientists Peace of mind Contrast
Resolution Precision

Ease of use DICOM

HOLO

G

Designed to rapidly deliver images
with excellent image quality
for Scientists.

“I am really impressed with the sharpness
and contrast of the images. It isdefinitely next-generation image quality.”– W. Dean Wallace M.D., Professor, Pathology and Laboratory Medicine, David
Geffen School of Medicine at UCLA

Aperio GT 450 utilizes a highperformance 40x objective
manufactured by Leica, thecompany that has engineered
world class optics since 1841.

2For research use only. Not for use in diagnostic procedures.

YDIGI

Excellent image quality using Leica
optics.
Automated image quality check andslide calibration during each scan.
Small footprint, large capacity.
No-touch continuous rack loading
during scanning.

TAL

PA

32

32 secscan speed
at 40x*.

Assign priority slides.
Z-Stack Multiplane scanning that
produces a composite, 3D image.**
Automated Narrow Stripe enablinga rescan when the system detects
image.

Aperio GT 450 open face design allows you tocontinuously load racks while scanning is in progress
to maximize productivity.

SEC

20x magnification available**TO8181 slides
per hourat 40x*.

PER HRL

O

120,000
PER YEARGYScan 120,000 slides
per year operating
the Aperio GT 450 foraround 5 hours/day*.

*15mm x 15mm scan area @ 40x; assumes 5 hr. scan time per day for 300 work days per year

Featuring automatic image quality control,
so you have image quality confidence before your scansreach the Scientist.
For research use only. Not for use in diagnostic procedures.

HStats page allows you to view slides scanned/day/month/year, average scan area and average scan speed.

DIGITAAperio GT 450 illuminates tissue from both sides of theslide resulting in a 99.5% accurate tissue finder thatrecognizes faintly-stained tissue while excluding:> Pen marks> Stain residue> Scratches> DustLPA

View and share images atmultiple locations.

Z-stacking enables scientists toreview slide samples at varied levelsof thickness, similar to a traditional
microscope.**“Good cellular details at high power and good focus
throughout the tissue.”– Sally Agersborg, MD, PhD,
Medical Director, NeoGenomics Laboratories, Inc.

THOLOAperio Viewer or
Aperio ImageScope**
Integrated LIMS/LIS> ER/PR/Her2> Ki67> P53> Lung Cilia> H Pylori

4For research use only. Not for use in diagnostic procedures.

YAperio GT 450 applications:> Cancer research> Toxicology research> Basic cell biology research> Immunology research> Digital archiving> Drug development studies

Access and organize your cases with Aperio eSlide Manager integrated into an LIS.

> Cellular grooves> Chromatin> Intracellular bridges> NucleoliGDIG

Fast scansITALPANo shipping Confidence

Next generation imaging for Researchers Auto QC Fast-paced

Be more productiveFirst-timescansuccessBe on time
Cross-training

Easy to use Continuous loading

THOLO

The products shown above, the HistoCore SPECTRA Workstation, incombination with the Aperio GT 450, are for Research Use Only (RUO).

5
For research use only. Not for use in diagnostic procedures.

Y

Designed to deliver rapid
results with confidence
for researchers.

“The Aperio GT 450 is very easy
to use and a companion in the lab.”
Directly load racks from coverslipper to scanner.

G– Brittney Hosac - Lab Assistant, NeoGenomics

DI

GI

Login controls

TA

SecurityHigh speed data transferLPA

Easy setup

Store and forward
DICOM or SVS compatible

Next generation imaging for IT Professionals Flexibility
Large storage Encryption

THOLO

G

Designed to deliver fast, secure,and scalable IT architecture for IT
Professionals.

“The IT architecture for the Aperio GT 450, including
the SAM central hub, is a gigantic leap forward toscale and support digital pathology IT operations.”– Chris Khacherian, UCLA Program Manager, Service Delivery, DGIT | Digital Technology

A secure, flexible and fast
IT solution to scale up yourDigital Pathology operations.

6For research use only. Not for use in diagnostic procedures.

YDIG

Cyber security including
encryption and login controls.

ITA

HL7 and PACS ready, forintegration into LIS, LIMS or PACS.

LPA

T

Securely scan slides at a spoke location and store images at a
Hub location for all sites to log in and view images.

HO

L

Store and forward: store images
temporarily then transfer during
low IT traffic times.

OGY

Set up user-specific log infor each Aperio GT 450.

A centralized Scanner Admin
Manager (SAM) will allow IT
professionals to scale up Digital
Pathology operations securely
and efficiently.

IT OFFICESAM
APPLICATIONSSOFTWARE

No more workstations
needed. SAM server andsoftware allow IT managers
to set up and monitor GT 450
scanners via the network,
including dashboard status
views, PIN controls andlog out times.

IT ROOMSAM SERVERLABGT 4507For research use only. Not for use in diagnostic procedures.

GT 450GT 450GT 450

LeicaBiosystems.com

From the lab to the IT room the Aperio GT 450 was designed for Scientists, Researchers, and IT Professionals**The Aperio GT 450 Release 1.3 consists of three
upgrades that improve image quality and flexible
scanning solutions in research settings: 20x
magnification, Automated Narrow Stripe Scanning,and Z-Stack Scanning.

Aperio GT 450 Summary of Specifications

Part Number

Description

23GT450

Aperio GT 450 Scanner

23GT450SAM

Aperio GT450 Scanner Admin Manager(SAM) Server

23GT450SAMSW

Aperio GT450 Scanner Admin Manager(SAM) Applications Software

Maximum Slide Capacity

450

Rack capacity

15 racks of 30 slides, 15 racks of 20 slides

Racks compatible with Leica HistoCore SPECTRA Workstation

Yes

23Dell740XD21TB

Dell 740 XD image storage DSR 21 Terabytes

Continuous rack loading while scanning

Yes

23Dell740XD42TB

Dell 740 XD image storage DSR 42 Terabytes

Priority rack scanning

Yes

23Dell740XD85TB

Dell 740 XD image storage DSR 85 Terabytes

Z-stacking

Yes

23Dell740XD138TB

Dell 740 XD image storage DSR 138 Terabytes

Magnification

20x, and 40x

23VS101

Resolution

0.26 μm/pixel at 40x

Scan speed (15mm x 15mm area at 40x)

32 secAperio viewing station (includes calibrated monitor,workstation, Aperio ImageScope viewer and optimized
ICC file)

Sustained throughput (15mm x 15mm area at 40x)

81 slides/hr

23GT450ZSTACKSW

Feature Pack

Automated Image Quality Check

Yes

Slide sizes accepted

1x3

Field of View (FOV)

1mmBar code engines

1D and 2D symbology

Dimension

20.8” (52.83 cm) W x 28” (71.12 cm) L x 19.5” (49.53 cm) H

Weight

140 lbs (63.5 kg)*Parts shown are each sold separately.

SCAN OR
CLICK TO
LEARN
MORE

LEICA BIOSYSTEMS IS AN INTERNATIONAL COMPANY WITH A STRONG NETWORK OF WORLDWIDE CUSTOMER SERVICES
For detailed contact information on your nearest sales office or distributor please visit our website: LeicaBiosystems.com

Copyright © 2023 Leica Biosystems, a division of Leica Microsystems Inc. All Rights Reserved. LEICA and the Leica logo
are registered trademarks of Leica Microsystems IR GmbH. Aperio, GT, and GT 450 are registered trademarks of the Leica
Biosystems group of companies in the USA and optionally in other countries. Other logos, product and/or company names
might be trademarks of their respective owners.
230234 Rev B IMC-1142-REV-B • 10/2023

Leica Biosystems is a global leader in workflow solutions and automation. As the only company to own the workflow from biopsy todiagnosis, we are uniquely positioned to break down the barriers between each of these steps. Our mission of “Advancing Cancer
Diagnostics, Improving Lives” is at the heart of our corporate culture. Our easy-to-use and consistently reliable offerings help improve
workflow efficiency and diagnostic confidence. The company is represented in over 100 countries. It has manufacturing facilities in 9countries, sales and service organizations in 19 countries, and an international network of dealers. The company is headquartered in
Nussloch, Germany. Visit LeicaBiosystems.com for more information.