Aperio GT 450 Release 1.3.1
CUSTOMER NOTICE

1. Introduction
The purpose of a Customer Notice is to provide timely communication regarding updates to Leica Biosystems
product user manuals. This Customer Notice contains information about your Leica Biosystems product thatwill be included in a future release of one or more user manuals for your product. This information mayinclude new instructional content, updated specifications, or additional information about the use or care ofyour product. Use this document as supplementary information until the revised user manuals are available.
This Customer Notice provides information and instructions for using the new features provided with theAperio GT 450 Release 1.3.1.
This document contains the following sections:
1. Introduction
2. Aperio GT 450 Release 1.3.1 overview
3. Set the Pyramid Level Downscaling option in SAM

Products Affected
Aperio GT 450 Scanner, Aperio GT 450 Scanner Administration Manager Software, and Aperio GT 450
Controller Version 1.3.1.

User Manuals Affected
The information contained in this document will be incorporated into the following user manuals upon theirnext major scheduled release:
Document Title
Aperio GT 450 IT Manager and Lab Administrator’s GuideAperio GT 450 Release 1.3.1 Customer Notice, CN-0004 Revision A
Copyright © 2024 Leica Biosystems Imaging, Inc.

Base Document NumberMAN-0394

1Aperio GT 450 Release 1.3.1 Customer Notice

2. Aperio GT 450 Release 1.3.1 overview
The Aperio GT 450 release 1.3.1 includes the following feature updates:

2x pyramid level downscaling support
With Aperio GT 450 Release 1.3.1, you have the option of changing the pyramid level downscaling from thedefault of 4x to 2x. This option is set in the Aperio GT 450 SAM software.
When displaying Aperio GT 450 scanned images, some third-party viewing software solutions must
interpolate the image data as the user navigates through the available magnifcation levels. This interpolation
process can cause a decrease in viewing performance. Setting the pyramid level downscaling to 2x can
increase viewing performance by enabling third-party viewing software solutions to display all available
magnification levels with less interpolatation of the image data.
The illustrations below show how 2x pyramid level downscaling provides the viewing software direct accessto a greater range of magnification levels.
4x pyramid level downscale

2x pyramid level downscale

When you enable the 2x pyramid level downscaling option, the image size for 2x downscaled
images is approximately 15% to 20% greater than the default 4x downscaled images,
depending on the slide image.
For more information on enabling 2x pyramid level downscaling in SAM, see Set the Pyramid Level
Downscaling option in SAM (on page 3).

Aperio GT 450 Release 1.3.1 Customer Notice, CN-0004 Revision A
Copyright © 2024 Leica Biosystems Imaging, Inc.

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3. Set the Pyramid Level Downscaling option in SAM
Only a user who is assigned the Lab Admin role can make configuration changes.
To adjust the new Pyramid Level Downscaling settings for a scanner, follow these steps:
1. Log in to the SAM software.
2. When the SAM Home screen appears, confirm that the Scanners icon in the banner is selected, and thepage shows the list of scanners. Click the Scanners icon to display the list, if necessary.

3. Click the System Information icon for the appropriate scanner.

4. In the left pane of the System Information page, click Settings to open the Scanner Config page.

Aperio GT 450 Release 1.3.1 Customer Notice, CN-0004 Revision A
Copyright © 2024 Leica Biosystems Imaging, Inc.

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Aperio GT 450 Release 1.3.1 Customer Notice

5. On the Scanner Config page, click Edit, and then scroll to the bottom of the page.
6. In the PYRAMID LEVEL DOWNSCALING field, select 2x to enable the 2x Pyramid Level Downscaling
option.

7. Click Save.
.

Aperio GT 450 Release 1.3.1 Customer Notice, CN-0004 Revision A
Copyright © 2024 Leica Biosystems Imaging, Inc.

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Aperio GT 450 Release 1.3.1 Customer Notice

Notices
CN-0004, Revision A | February 2024
This manual applies to Aperio GT 450 Controller, Aperio GT 450 Console, and Aperio GT 450 SAM versions 1.3.1 and later.
Original Instructions.

Copyright Noticell

Copyright © 2024 Leica Biosystems Imaging, Inc. All Rights Reserved. LEICA and the Leica logo are registered trademarksof Leica Microsystems IR GmbH. , GT, and GT 450 are trademarks of Leica Biosystems Imaging, Inc. in the USA andoptionally in other countries. Other logos, products, and/or company names might be trademarks of their respective
owners.
This product is protected by registered patents. For a list of patents, contact Leica Biosystems.

Customer ResourceslFor the latest information on Leica Biosystems products and services, please visit LeicaBiosystems.com/Aperio.

Contact Information – Leica Biosystems Imaging, Inc.
Headquarters
Leica Biosystems Imaging, Inc.
1360 Park Center Drive
Vista, CA 92081
USATel: +1 (866) 478-4111 (toll free)Direct International Tel:+1 (760) 539-1100

Customer Support
Contact your local support representative with any query andservice request.
https://www.leicabiosystems.com/contact-us/

For research use only. Not for use in diagnostic procedures.

815477020228, 815477020464, 815477020471, 815477020563
23GT450, 23GT450SAM, 23GT450SAMSW, 23GT450ZSTACKSW

Aperio GT 450 Release 1.3.1 Customer Notice, CN-0004 Revision A
Copyright © 2024 Leica Biosystems Imaging, Inc.

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