Program at a glance<The 11th Chronic Kidney Disease Frontier Meeting>February 20 (Sun), 2022

13:00

13:00-13:05 Opening Remarks

13:05-13:53
Oral Presentations< Basic 1 >Chairs: Takaaki Abe, Hirokazu Okada
O-1 ~ 4

14:00

15:00

13:55-14:25
Sponsored Seminar 1
Sponsored by Chugai Pharmaceutical Co.,Ltd.
Chair: Motoko Yanagita
Speaker: Naoki Nakagawa

14:35-15:25
Oral Presentations< Basic 2 >Chairs: Masafumi Fukagawa, Ichiei Narita
O-5 ~ 815:25-15:55
Sponsored Seminar 2
Sponsored by Sumitomo Dainippon Pharma Co.,Ltd.
Chair: Takashi Wada
Speaker: Akira Mima

16:00
16:05-17:05
Oral Presentations< Clinical >Chairs: Kunihiro Yamagata, Hitoshi Sugiyama
O-9 ~ 13

17:00
17:05-17:45
Sponsored Seminar 3
Sponsored by Ono Pharmaceutical Co., Ltd. / AstraZeneca K.K.
Chair: Naoki Kashihara
Speaker: Kei Fukami

18:00

17:55-18:40
Controversy in the Treatment of Glomerulonephritis
Chairs: Masaomi Nangaku, Yon Su Kim
Panelists: Li Zuo, Kearkiat Praditpornsilpa, Chi-Chih Hung

19:00

18:40-19:25
Invited Lecture
Treatment of ANCA-Associated Vasculitis
Chair: Shoichi Maruyama
Speaker: David Jayne
19:25- Closing Remarks－3－13:00-13:05

Opening Remarks

13:05-13:53

Oral Presentations“Basic1”
 ohoku University School of Medical Scineces/Medicine, Japan）
Chairs：Takaaki Abe（‌T epartment of Nephrology, Saitama Medical University, Japan）
Hirokazu Okada（‌DO-1

DZNEP, A HISTONE MODIFICATION INHIBITOR, SUPPRESSES RENALFIBROSIS BY INHIBITING HIF1 Α BINDING TO TIMP2 GENE THROUGHREDUCING OPEN CHROMATIN AREA
Tomotaka Yamazaki，Imari Mimura，Tetsuhiro Tanaka，Masaomi Nangaku
Division of Nephrology and Endocrinology, The University of Tokyo Graduate School of Medicine, JapanO-2

Advanced tertiary lymphoid tissues in protocol biopsies are associated with
progressive graft dysfunction in kidney transplant recipients
Yu Ho Lee1, 2，Yuki Sato1, 3，Mitsuru Saito4，Shingo Fukuma5，Masaya Saito6，
Shigenori Yamamoto1, 3，Atsushi Komatsuda6，Nobuhiro Fujiyama7，Shigeru Satoh7，
Sang-Ho Lee8，Peter Boor9, 10, 11，Tomonori Habuchi4，Jürgen Floege10，
Motoko Yanagita1, 121

Department of Nephrology, Graduate School of Medicine, Kyoto University, Japan,Division of Nephrology, Department of Internal Medicine, CHA Bundang Medical Center, CHA University,Republic of Korea,
3Medical Innovation Center TMK Project, Kyoto University, Japan,
4
Department of Urology, Graduate School of Medicine, Akita University, Japan,
5
Human Health Sciences, Graduate School of Medicine, Kyoto University, Japan,
6
Department of Hematology, Nephrology, and Rheumatology, Graduate School of Medicine, Akita University,Japan,
7Center for Kidney Disease and Transplantation, Akita University Hospital, Japan,
8
Division of Nephrology, Department of Internal Medicine, Kyung Hee University, Republic of Korea,
9Institute of Pathology, RWTH University of Aachen, Germany,
10
Division of Nephrology, RWTH University of Aachen, Germany,
11Electron Microscopy Facility, RWTH University of Aachen, Germany,
12Institute for the Advanced Study of Human Biology (ASHBi), Kyoto University, Japan
2O-3

Profile of circulating microRNAs associated with hyperglycemia and their effect onkidney function decline in patients with type 2 diabetes
Hiroki Kobayashi1, 2，Eiichiro Satake2，Zaipul I. Md. Dom2，Masanori Abe1，Andrzej S. Krolewski2
1

Division of Nephrology, Hypertension and Endocrinology, Nihon University School of Medicine, Japan,
Research Division, Joslin Diabetes Center, Harvard Medical School, Boston, MA, USA

2O-4

Effects of sodium–glucose cotransporter 2 inhibitor, canagliflozin, on glomerular
hyperfiltration and oxidative stress in mice with type 2 diabetes
Megumi Kondo，Kengo Kidokoro，Hiroyuki Kadoya，Yoshihisa Wada，Hajime Nagasu，Tamaki Sasaki，Naoki Kashihara
Kawasaki Medical School, Japan－6－13:55-14:25

Sponsored Seminar 1

Sponsored by Chugai Pharmaceutical Co.,Ltd.

 epartment of Nephrology, Graduate School of Medicine, Kyoto University,
Chair：Motoko Yanagita（‌DJapan）SS-1

Update on the treatment of refractory nephrotic syndrome
Naoki Nakagawa
Division of Cardiology, Nephrology, Pulmonology and Neurology, Department of Internal Medicine, Asahikawa
Medical University, Japan

14:35-15:25

Oral Presentations“Basic2”
 ivision of Nephrology, Endocrinology and Metabolism Tokai University
Chairs：Masafumi Fukagawa（‌DSchool of Medicine, Japan）DivisionofClinical Nephrology and Rheumatology, Kidney Research Center, Niigata
Ichiei Narita（‌
University, Japan）O-5

Nicotinic acetylcholine receptor agonist reduces acute lung injury after renal
ischemia-reperfusion injury by acting on splenic macrophages in mice
Daiki Goto，Soichiro Nagata，Yoshitaka Naito，Shinsuke Isobe，Takamasa Iwakura，Tomoyuki Fujikura，Naro Ohashi，Akihiko Kato，Hideo Yasuda
First Department of Medicine, Hamamatsu University School of Medicine, Japan

O-6

Leukotriene B4-BLT1-dependent neutrophil recruitment contributes to thepathogenesis of crescent glomerulonephritis
Ryotaro Shioda1, 2，Airi Jo-Watanabe2, 3，Toshiaki Okuno2，Kazuko Saeki2，
Maiko Nakayama1，Takehiko Yokomizo2，Yusuke Suzuki1
1

Department of Nephrology, Juntendo University Faculty of Medicine, Japan,
Department of Biochemistry, Juntendo University Graduate School of Medicine, Japan,
3
AMED-PRIME, Japan Agency for Medical Research and Development, Japan
2O-7

Hepatic phosphate uptake and hepatic afferent nerve transmission play pivotal
roles in the maintenance of serum phosphate levels in a FGF23, PTH, and vitamin
D independent mannerSeiichi Yasuda，Kazunori Inoue，Atsuhiro Imai，Hiroki Okushima，Yusuke Katsuma，
Ayumi Matsumoto，Isao Matsui，Yoshitaka Isaka
Department of Nephrology, Osaka University Graduate School of Medicine, JapanO-8

Dietary magnesium insufficiency induces salt-sensitive hypertension in miceassociated with reduced kidney COMT activity
Asako Kumagai1，Keizo Kanasaki21

Department of Obstetrics and Gynecology, Juntendo University, Japan,
Department of Internal Medicine I, Faculty of Medicine, Shimane University, Japan

2－7－15:25-15:55

Sponsored Seminar 2

Sponsored by Sumitomo Dainippon Pharma Co.,Ltd.

 epartment of Nephrology and Laboratory Medicine, Kanazawa University, Japan）
Chair：Takashi Wada（‌DSS-2

Management of type 2 diabetes in diabetic kidney disease
Akira Mima
Department of Nephrology, Osaka Medical and Pharmaceutical University, Japan

16:05-17:05

Oral Presentations“Clinical”
 epartment of Nephrology, Faculty of Medicine, University of Tsukuba,
Chairs：Kunihiro Yamagata（‌DJapan） kayama University Hospital, Japan）Hitoshi Sugiyama（‌OO-9

High chronicity index of the revised International Society of Nephrology/Renal
Pathology Society (ISN/RPS) classification of lupus nephritis is associated withincreased risk of end-stage kidney disease: a retrospective single-center study
Shiori Nakagawa1，Tadashi Toyama1, 2，Yasunori Iwata1，Megumi Oshima1，
Hisayuki Ogura1，Koichi Sato1，Yuta Yamamura1，Taro Miyagawa1，Shinji Kitajima1，
Akinori Hara1, 3，Norihiko Sakai1，Miho Shimizu1，Takashi Wada1
1

Department of Nephrology and Laboratory Medicine, Kanazawa University, Japan,
Innovative Clinical Research Center, Kanazawa University Hospital, Japan,
3
Department of Public Health, Kanazawa University, Japan2

O-10

Increasing gender difference in the incidence of end-stage of renal disease inOkinawa
Chisato Fukuhara1，Kentaro Kohagura2，Iseki Kunitoshi3
1

Department of Nephrology, Heartlife hospital, Japan,
Dialysis Unit, University Hospital of the Ryukyus, Japan,
3
Okinawa Heart and Renal Association, Japan
2

O-11

Long-term care needs and incidence of end-stage kidney disease: a retrospectivecohort study
Ryuichi Yoshimura1，Ryohei Yamamoto1，Maki Shinzawa2，Rie Kataoka3，Nami Ikeguchi3，Suzuna Kanda3，Yuki Nii3，Hiroshi Toki1，Toshiki Moriyama1
1

Health and Counseling Center, Osaka University, Japan,
Department of Nephrology, Osaka University Graduate School of Medicine, Japan,3Health Promotion Division, Neyagawa City Public Health Center, Japan
2O-12

Urinary phenyl sulfate predict the 2-year ACR deterioration in a DKD cohort
Koichi Kikuchi1，Ryota Kujirai3，Yotaro Matsumoto3，Koki Mise4，
Tomohiro Nakamura2，Jun Wada4，Yoshihisa Tomioka3，Takaaki Abe1, 5
1Tohoku University Hospital, Japan,Tohoku Medical Megabank Organization, Tohoku University, Japan,
3
Tohoku University Graduate School of Pharmaceutical Sciences, Japan,
4Okayama University, Japan,
5Tohoku University Graduate School of Biomedical Engineering, Japan
2－8－O-13

Performance of new CKD EPI equation without race among Japanese patients
Yoshinari Yasuda1, 2，Masaru Horio1，Enyu Imai1，Tsuyoshi Watanabe1，Akira Hishida1，Shoichi Maruyama2，Seiichi Matsuo1
1

Study Group of developing the Japanese equation for estimated GFR, Japan,
Department of Nephrology, Nagoya University Graduate School of Medicine, Japan2

17:05-17:45

Sponsored Seminar 3

Sponsored by Ono Pharmaceutical Co., Ltd. / AstraZeneca K.K.

 ivision of Nephrology and Hypertension, Kawasaki Medical School, Japan）
Chair：Naoki Kashihara（‌DSS-3

SGLT2 inhibitor as a promising therapeutic strategy for chronic kidney disease
Kei Fukami
Division of Nephrology, Department of Medicine, Kurume University School of Medicine, Japan

17：55-18:40 Controversy in the Treatment of Glomerulonephritis

 ivision of Nephrology and Endocrinology, the University of Tokyo Graduate
Chair： Masaomi Nangaku（‌DSchool of Medicine, Japan）Yon Su Kim（‌S eoul National University College of Medicine, Republic of Korea）

Panelists Li ZuoPeking University First Hospital, ChinaKearkiat Praditpornsilpa
Chulalongkorn University, Thailand

Chi-Chih Hung
Kaohsiung Medical University, Taiwan

18:40-19:25

Invited Lecture epartment of Nephrology, Internal Medicine, Nagoya University Graduate
Chair：Shoichi Maruyama（‌D
School of Medicine, Japan）IL-1

Treatment of ANCA-Associated Vasculitis
David Jayne
University of Cambridge, UK

19:25-

Closing Remarks－9－