Laboratory of Biohistory
JT Biohistory Research Hall(Left) Guest Professor

Zhi-Hui SU

su.zhihui(Right) Guest Professor

Chikara HASHIMOTO

hashimoto

Guest Associate Professor

Hiroki ODA

hoda

URL: https://www.brh.co.jp/
By deciphering the historicity,
diversity, and commonality of living
things written in genomes, we
conduct experimental researches
on development, evolution, andecosystems of living things, as well
as research on expression of study
results. By investigating diverse
organisms without focusing on
individual genes or species, webelieve that the fundamentals ofdevelopment and speciation in theprocess of evolution can berevealed. We place the love of living
things at the basis of ourresearches and also disseminate it.
In the Laboratory of Biohistory, weare conducting the following studies
on evolutionary and developmental
biology.
Insect-plant interactions andevolution

Interactions between organisms are one ofthe driving forces of evolution and speciation.
In particular, insects and plants interact witheach other in various ways, such as foodresources and pollination mutualism. The
diversities of insects and plants have been
facilitated by establishing mutually adaptiverelationships in these interactions. We
investigate the processes and mechanisms ofevolution and speciation in insect-plantinteractions.
Degenerative evolution of insect
flight function

The acquisition of wings is the mostimportant event in the evolutionary process ofinsects, and it is believed to have contributed
to their diversity. On the other hand, not afew extant insects have lost their wings andflight ability. We investigate the molecularmechanisms underlying the degenerative
evolution of flight function in insects.

Origin and evolution ofcell and developmental
systems in multicellularanimalsMulticellular animals have
epithelial tissues that shape thebody, and have diversified theirform since their success inorganizing body axes andrepetitive structures. Whatkinds of cell anddevelopmental systems existed
at the origin of animal
diversity, and what kinds ofchanges have driven thediversification. We are tacklingthese problems bothexperimentally andtheoretically.

表現を通して生きものを考える「生命誌」 の研究成果を刊行物、展示、映像などを通して発信、科学の新たな表現・研究に取り組んでいる。

Mechanism of chordata
gastrulation
Gastrulation is a critical stage
in the formation of thefundamental body plan. We
constructed a brand-new modelof amphibian gastrulation, andfound that the model isadaptable to the chordata
species. Now we are interested
in how this tissue movements
were conserved in throughout
the species.
Relationship between cell
cycle and differentiation
In the study of vertebrate neuralcrest and planarian stem cell, we
found that the causal relationshipbetween proliferation anddifferentiation is conserved among
multicellular organisms. Thus, we
propose that proliferation maintains
the undifferentiated status and cell
cycle exit to G0 dictates cells to
become competent to accept
induction signals.

BecomeamemberoftheBiohistory

Laboratory, which is creating a new formof life research through comprehensive

study and expression of the historicity
and relationships of living things, including
development, evolution, and ecology, andmake the most of new ideas.

JT Biohistory Research Hall
1-1 Murasaki-cho, Takatsuki, Osaka
569-1125, Japan
TEL: +81-72-681-9750
FAX : + 81-72-681-9743
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