IMMUNOTOXICOLOGYSpecialty Section
Pre-SOT Bulletin
2016-2017
Executive Committee

President’s Message

President
L. Peyton Myers

Greetings all!
I hope that your anticipation is building in preparation for the
SOT 56th Annual Meeting in Baltimore, MD. Once again we arein “Charm City”, and it should be a great meeting.

Vice President
Victor J. Johnson
Vice President-Elect
Jamie DeWitt
Secretary/Treasurer
Kristen A. Mitchell
Past President
Rafael A. Ponce
Senior Councilor
Haley Neff-LaFord
Junior Councilor
Rodney Prell
Postdoc Representative
Angela Groves
Student Representative
Jiajun (Brian) Zhou
The Immunotoxicology Specialty
Section (ITSS) Newsletter ispublished three times a year
(Summer, Fall, and Winter). If you
would like to share an item of interest
with members of the ITSS, please
send it to the Communications
Committee Co-Chairs. All comments
and suggestions are welcome.
Jiajun (Brian) Zhou
zhoujiaj@msu.edu
Angela Groves
Angela_Groves@URMC.
Rochester.edu
Kristen A. Mitchell
kristenmitchell@boisestate.edu

March 2017

The program for 2017 is rich with many immunotoxicologysponsored sessions and additional immunotoxicology program
offerings. I would like to thank Vic Johnson and the 2016-2017
Program Committee for working diligently to support such arobust program. Check these out and please do support them byyour attendance and discussions as you can. Also, don’t forget
to support the efforts of Jamie DeWitt and the current Program
Committee as they plan for San Antonio. Information about 2018
SOT Annual Meeting proposal submissions is included in thisnewsletter.
This year the ITSS reception will be held in the Baltimore Hilton(Key Ballroom 9) after the ITSS Networking/Mentoring event in
the same location. I would like to thank Jamie DeWitt, Brian
Zhou, Angela Groves, and the rest of the Education Committee
for planning the event. We hope to continue this event to help
encourage the careers of our budding immunotoxicologists. The
Networking/Mentoring event begins at 4:30 and the ITSS
reception meeting starts at 6:00.
Please be sure to attend the ITSS reception. It is a wonderful
opportunity to cross paths with old friends and colleagues, tocelebrate the wonderful accomplishments of our members, toWhat’s inside?
President’s Message……………………………………………………1
Student Post-doctoral Committee Report …….........……....….…..3
ITSS-sponsored programs at SOT 2016…….......……….……….....4
Call for proposals for 2018....................................................... ........6
News and Noteworthy contributions................................................7
Announcements.................................................................................8
Job Opportunities...............................................................................9
Recent Immunotoxicology Publications........................................11
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Immunotoxicology Specialty Section

President’s Message, continued:
meet our enthusiastic students and postdocs, and of course, get caught up on the business of
the ITSS. Your nominations led to the selection of awardees who have made significant
contributions to the field of immunotoxicology. We will announce this year’s ITSS award
recipients at the business meeting portion of the reception. I hope you will join us to honor
these well-deserving awardees. Additionally, you will be introduced to your new ITSS 20172018 Executive Committee.
As was announced at the ITSS business meeting in 2016, we have partnered with ILSI/HESI toformalize a symposium/workshop session for Immunotoxicology. The first session will precede
the ILSI/HESI Spring Meeting and will be held at MedImmune in Gaithersburg, MD from April
18-19. If you have not registered, please consider registering. It will be a great session on Tcell biology with a focus on Immuno-onolcogy. The ITSS Executive Committee has worked intandem with ILSI/HESI to help organize sessions and find speakers for the course. I want tothank all the ITSS members who have helped make this course a success.
I am thrilled that our SS has such strong representation on SOT Council as well as in otherelected and appointed committees at SOT. Two ITSS members are SOT Past Presidents(Michael Holsapple and Norbert Kaminski) as is the current SOT VP-Elect, Leigh Ann Burns
Naas. With the dedication of our ITSS leaders, we can easily partner with other groups within
SOT and beyond.
Along those lines, we are working closely with the SOT Council plans to further enhance the
SOT international presence. ITSS has been a leader in international partnership for many
years with our International Committee. With the leadership of Mitch Cohen, Kazu Nakamura,and others, we have developed a scientist exchange between ITSS and the Japanese Societyof Immunotoxicology. Many of you have participated in these exchanges and we greatly value
our ITSS/JSIT partnership. With the election of Emanuela Corsini as the VP-Elect for ITSS,
who hails from Italy, we hope to better establish more formal partnerships with our European
colleagues from “across the pond”. I hope that this will begin an expansion of the partnerships
for ITSS as we work to network across the globe.
I wish you the best and look forward to seeing you shortly in Baltimore.
Dr. Laine Peyton Myers
President, ITSS 2016 - 2017

March 2017

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Immunotoxicology Specialty Section

Student & Postdoctoral Report:
The SOT Annual Meeting is fast approaching and we hope that you are getting excited topresent your research and to check out all the events taking place. We would like to point out
some of the many amazing, useful activities and networking events that this meeting offers tostudents and postdocs so that you can take advantage of them!
On Sunday March 12th, expand your knowledge of some of the leading-edge fields of
toxicology by attending the Continuing Education Courses. Also on Sunday, from 7:30 9:00 p.m. at the Hilton Baltimore Holiday Ballroom 4, you can learn more about specialty
sections and regional chapters at the Student/Postdoctoral Scholar Mixer. It is FREE for all
students and postdocs. This is also a great opportunity to get more information about anumber of networking and educational events that the Graduate Student Leadership
Committee and Postdoctoral Assembly will be hosting throughout the week, including: Chatwith an Expert, Mentoring Breakfast, Trainee Discussions with Plenary Session
Presenters, and Poster Tours. These events will enable you to get great face-to-face timewith leading experts in toxicology. Please sign up for one or all of these events! If you are a
postdoc, don’t miss the PDA Luncheon on Tuesday, March 14th, 12:00 - 1:15 p.m. taking
place at CC Room 324.
Looking to learn more about career options in the field of toxicology? Attend the Career
Exploration through Speed Informational Interviews on Tuesday, March 14th, 1:20 - 2:40
p.m. at CC 324. Also, be sure not to miss out on the always entertaining quiz show “ToxShowdown” on Tuesday, March 14th, 7:30 - 9:00 p.m at the Hilton Baltimore Holiday
Ballroom 3.
Finally, please mark your calendars for the ITSS mentoring event to be held on Monday,
March 13th, 4:30 - 5:30 p.m. at the Hilton Baltimore Key Ballroom 9. Here you will be able tosit down with professionals from a variety of work sectors who will discuss their careers andanswer questions. You can stop by our poster at the Student/Postdoc mixer for more
information.
If you would like to get involved in any of the ITSS committees, please contact Angela Groves(Angela_Groves@URMC.Rochester.edu) or Jiajun (Brian) Zhou (zhoujiaj@msu.edu).
We look forward to seeing you in Baltimore!
Angela Groves, Ph.D.
Jiajun (Brian) Zhou

March 2017

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Immunotoxicology Specialty Section

ITSS- Sponsored events @ SOT 2017:
March 13, 2017
Symposium
2:00pm 4:45pm

Workshop
2:00pm 4:45pm

Lifespan Neuroimmunotoxicology: Age-Dependent Neuroimmune
Dyshomeostasis Caused by Pollutants, Pathogens and Psychoactive
Substances(Chairs: Nick Filipov, University of Georgia; Vic Johnson, Burleson ResearchTechnologies)
Bispecific Molecules: Nonclinical and Clinical Development Challenges(Chairs: Pedro Del Valle, US FDA; Patricia Ryan, MedImmune, LLC)

March 14, 2017
Symposium
2:00pm 4:45pm

Symposium
2:00pm 4:45pm

Chemically Induced Neuroinflammation and “Sickness Behavior”
Disorders(Chairs: G. Jean Harry, NIEHS/NIH; James O'Callaghan, CDC-NIOSH)
Emerging Concepts in Nonclinical Development of Immuno-Oncology
Agents: Enabling Translation of Nonclinical Pharmacology and Safety
Information to First-in-Human Clinical Trials(Chairs: Vijayapal Reddy, Eli Lilly and Company; Jacqueline Kinyamu‐Akunda,
Novartis Institute for Biomedical Research)

March 15, 2017
Symposium
9:30am 12:15pm

Symposium
2:00pm 4:45pm

Workshop
8:30am 11:15pm

March 2017

The Skin As A Metabolic And Immune-Competent Organ: Implications for
Pharmaceutical Development and Safety Assessment(Chairs: Yoshiro Saito, MHLW Japan; Jeanine Bussiere, Amgen, Inc.)
Enhancing the Clinical Benefit of Cancer Drugs: Toxicity As a Therapeutic
Target(Chairs: Syril Pettit, HESI; Brian Berridge, GlaxoSmithKline)
Biological Advances to Help Navigate the Nonclinical Safety Assessment
Strategy in Cancer Immunotherapy: Utility, Limitations, and Future
Direction(Chairs: Robert Li, Genentech; Jacintha Shenton, Janssen)

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Immunotoxicology Specialty Section

ITSS- Sponsored events @ SOT 2017:
Additional Sessions Relevant to Immunotoxicology
March 13, 2017
Platform
9:30am 12:15pm

Ozone and Inflammation

March 14, 2017
Daily Plenary
Pharmacogenomics of Drug Toxicity in Cancer: Making the Case for
SessionPrecision Medicine
8:00am –9:20amLecturer: Jun J. Yang, St. Judes Children’s Research Hospital

Poster
9:30am 12:15pm

Imunotoxicology

March 15, 2017
Poster
1:15pm –4:30pmAutoimmunity / Hypersensitivity

Poster
1:15pm –4:30pmInflammation and Disease

Poster
1:15pm –4:30pmMiniSymposium
5:00pm –6:20pmMarch 2017

Inflammation: Methods and Mechanisms

Immune Factors in Drug-Induced Liver Injury(Chairs: Robert A. Roth, Michigan State University and Tsuyoshi Yokoi, Nagoya
University Graduate School of Medicine)
Joint Mini-Symposium between Society of Toxicology and Japanese Society of
Toxicology

5

Immunotoxicology Specialty SectionCALLING ALL PROPOSALS!
Endorsement of Proposals
by the Immunotoxicology Specialty Section Program Committee
So you want to submit a program proposal for the 2018 SOT Annual Meeting in San Antonio.
What do you do and how do you do it?

FIRSTVisit SOT’s web site on proposals(https://www.toxicology.org/events/am/AM2018/proposal_guidelines.asp). Follow theirdirections for preparing your proposal. The directions are there to help you choose a session
type (Continuing Education? Workshop?) and encourage you to write abstracts and confirm
speakers BEFORE YOU SUBMIT YOUR PROPOSAL endorsement or to SOT!

SECOND
Secure endorsement from ITSS.
This means submitting your draft session proposal to the ITSS Program Committee
Chair (Jamie DeWitt, dewittj@ecu.edu) NO LATER THAN MAY 5, 2017. The SOT
proposal submission site closes on MAY 15, 2017. This 10 day period gives the ITSS time toreview your proposal, offer suggestions, and determine if they’re going to endorse yourproposal.

THIRD
Modify your proposal based on suggestions by the ITSS (they do it to help!) and submit yourproposal through the SOT submission site by MAY 15, 2017.

March 2017

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Immunotoxicology Specialty Section

Achievements:

Congratulations to Debra Laskin, PhD, for winning the
SOT 2017 Education Award. Debra is a Distinguished
Professor and Chair and the Roy A Bowers Endowed Chairof the Department of Pharmacology and Toxicology at
Rutgers University.

Congratulations to John I. Anetor, PhD, Professor of Chemical
Pathology/ Toxicology in the Chemical Pathology Department of theCollege of Medicine, at the University of Ibadan, Nigeria.
John was made the Lead (Principal) Consultant to the Federal
Ministry of Health of Nigeria's 'National Lead Poison Elimination,
Treatment and Strategic Intervention Scheme, delivered aninaugural lecture to his university entitled: IN SEARCH OF AN
ANTIDOTE FOR A POISONED WORLD, and nominated a memberof the National Health Research Ethics Committee (NHREC), a
statutory committee of the National Health Act of Nigeria.

Congratulations to Anthony M. Franchini, PhD,
Postdoctoral Fellow in the Department of Environmental
Medicine at the University of Rochester Medical School.
Anthony has received the Rochester Vaccine Postdoctoral
Fellowship, awarded annually to an outstanding
postdoctoral fellow working in the area of vaccine-related
research.

March 20177

Immunotoxicology Specialty Section

ANNOUNCEMENT!

FOR STUDENTS AND POSTDOCSMarch 20178

Immunotoxicology Specialty Section

JOB OPPOURTUNITY
Head of Investigative Immunotoxicology and Senior Scientific Director,
Biologics Toxicology
Work Location: 1400 McKean Road, Spring House, PA 19477 (County: Montgomery)
Description
Janssen Research and Development (R&D), L.L.C., a member of Johnson & Johnson's Familyof Companies, is seeking a Head for the Investigative Immunotoxicology group within the
Biologics Toxicology organization located in Spring House, PA. This is a new group/role within
the Biologics Toxicology organization and the Head will report directly to the Vice President andHead of Biologics Toxicology.
Janssen R&D, part of the Janssen Pharmaceutical companies of Johnson and Johnson (J&J),
develops treatments that improve the health and lifestyles of people worldwide. R&D areas
encompass novel targets in neurologic disorders, gastroenterology, oncology, infectious
disease, diabetes, hematology, metabolic disorders, immunologic disorders, and reproductive
medicine. For more about Janssen R&D, L.L.C., visit www.janssen.com/research-anddevelopment. Thriving on a diverse company culture, celebrating the uniqueness of ouremployees and committed to inclusion, J&J is proud to be an equal opportunity employer.
The Head of Investigative Immunotoxicology for Biologics Toxicology will be a part of Janssen
BioTherapeutics (JBIO; visit www.janssen.com/biotherapeutics ) and will support thedevelopment of novel biologic therapies which may include first-in-class technologies, stem celltherapies, monoclonal and multi-specific antibodies, alternative scaffolds, nucleic acidtherapeutics, and protein molecules.

The Head of Investigative Immunotoxicology for Biologics Toxicology will establish a new groupwithin Biologics Toxicology with the goal of evaluating potential immune system-related risks
associated with our biotherapeutic pipeline. The candidate will expand on existing laboratory
efforts in this area and, working with Project Toxicologists, will provide strategic and scientificinput to multidisciplinary Project Teams progressing biotherapeutics from discovery to first-inhuman and beyond. The Investigative Immunotoxicology group will use both internal andexternal (Contract Research Organizations) resources to generate data to support risk
assessment. It is anticipated that the Investigative Immunotoxicology group will work toestablish/develop novel assays/animal models to assist in understanding potential human risks
associated with candidates in our biologics pipeline.
The Head of Investigative Immunotoxicology will be part of the Biologics Toxicology Senior
Leadership Team. In addition, the candidate in this role will be part of the Biologics Toxicology
Scientific Advisory Board. This Board is responsible for the review and approval of nonclinicalsafety strategies as well as major issue review and recommendations for resolution.

March 2017

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Immunotoxicology Specialty Section

JOB OPPOURTUNITY, Cont.
The candidate will manage both PhD level and technical level staff. They will also be
responsible for the development of all employees within their group and within Biologics
Toxicology by supporting the development of Human Resources Planning (HRP) programs
including management development and training to meet current and future business needs
and provide an environment, which encourages the company's commitment to equal
employment opportunity and the value of a diverse work force. The candidate will also have
responsibility for budget, resource and timeline commitments for the IIT group.
The Head of Investigative Immunotoxicology for Biologics Toxicology will have a desire forlearning and innovation, and continue career development through participation in scientificmeetings, and increase visibility for self, Janssen BioTherapeutics and J&J throughpublications, participation in external organizations, and presentations at major scientific,
industry, and regulatory meetings.
Qualifications-Education and Experience• Ph.D. in immunology, immunotoxicology, toxicology or related discipline (pharmacology,
cell/tumor/molecular biology, or related field) and/or professional degree (DVM, VMD) withtraining or extensive experience in immunotoxicology, immunology or related biologic
disciplines• >12 years of pharmaceutical/biotechnology research management or related experience indrug development is required; direct experience with risk assessment for biotherapeutics isrequired• Knowledge of GLPs and Health Authority regulations and guidelines for the development of
biologics (e.g. ICH, FDA, EMEA, PMDA) is required• Proven track-record in leading complex scientific teams, including direct people management
experience• This role requires excellent communication and interpersonal skills, a high level oforganizational ability and attention to detail• Some travel (domestic and international) may be required dependent on project needs
Qualifications-Technical• Recognized/Established expert in the area of Immunotoxicology• Good communication skills, attention to detail, troubleshooting skills and ability to work
effectively in a collaborative environment• Strong scientific and technical skills including flow cytometry (particularly as applied to theimmune system), immunoassays and expertise in animal and cell based models• Ability to propose mechanistic hypotheses, design and oversee the execution of experiments.
• Exceptional diplomacy and negotiating skills• Leading edge knowledge of principles, concepts and practices in Immunotoxicology
BE VITAL in your career. Be seen for the talent you bring to your work. Explore opportunities
within the Johnson & Johnson Family of Companies.

March 201710

Immunotoxicology Specialty Section

Recent Immunology Publications:
Compiled by Angela Groves and Jiajun (Brian) Zhou. Anytime you have a new fully-publishedor electronically available article to report, please send the citation to Angela atangela_groves@urmc.rochester.edu.
Asthma, Allergy, Autoimmunity & Hypersensitivity
Bol-Schoenmakers M, Braber S, Akbari P, de Graaff P, van Roest M, Kruijssen L, Smit JJ, vanEsch BC, Jeurink PV, Garssen J, Fink-Gremmels J, Pieters RH. The mycotoxin
deoxynivalenol facilitates allergic sensitization to whey in mice. Mucosal Immunol. 2016 Feb
17.
Developmental Immunotoxicolgy
Brempelis, Katherine J., et al. Central Role of the TIR domain‐containing adaptor‐inducing
interferon‐β (TRIF) Adaptor Protein in Murine Sterile Liver Injury. Hepatology 2017.
Buoso E, Galasso M, Serafini MM, Ronfani M, Lanni C, Corsini E, Racchi M. Transcriptional
regulation of RACK1 and modulation of its expression: Role of steroid hormones andsignificance in health and aging. Cell Signal. 2017 Feb 9. S0898-6568(17)30050-5.
Vaessen SF, van Lipzig MM, Pieters RH, Krul CA, Wortelboer HM, van de Steeg E. Regional
expression levels of drug transporters and metabolizing enzymes along the pig and humanintestinal tract and comparison with Caco-2 cells. Drug Metab Dispos. 2017 Feb 2.
van der Wielen N, Ten Klooster JP, Muckenschnabl S, Pieters R, Hendriks HF, Witkamp RF,
Meijerink J. The Noncaloric Sweetener Rebaudioside A Stimulates Glucagon-Like Peptide 1
Release and Increases Enteroendocrine Cell Numbers in 2-Dimensional Mouse Organoids
Derived from Different Locations of the Intestine. J Nutr. 2016 Oct 26.
General Immunotoxicology
Adeniyi NA, Omotosho IO, Onifade A A, Anetor JI. An assessment of the modulatory effect ofzinc on humoral immune parameters in welders and cement block moulders in Ogbomosho,
Nigeria. J. Innov. Res. Health Sci. Biotechnol. 2016. 1(4):186-194.
Andreassen M, Bøhn T, Wikmark OG, Bodin J, Traavik T, Løvik M, Nygaard UC. Lack ofimmunogenic, allergenic and adjuvant properties of Cry1Ab protein after intragastric exposurein a food allergy model in mice. BMC Immunology, 2016. 17:10.
Andreassen M, Hjertholm H, Cravedi JP, Grob K, Alexander J, Nygaard UC. Effect of dietarypristane and other saturated mineral oils (MOSH) on autoimmune arthritis in rats. Tox Rep.
2017. 4:104–112.
Andres E, Barry M, Hundt A, Dini C, Corsini E, Gibbs S, Roggen EL, Ferret PJ. Preliminary
performance data of the RHE/IL-18 assay performed on SkinEthic(™) RHE for theidentification of contact sensitizers. Int J Cosmet Sci. 2016 Jul 25.

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Immunotoxicology Specialty Section

Recent Immunology Publications:
General Immunotoxicology, cont.
Bodin J, Groeng EC; Andreassen M, Dirven H, Nygaard UC. Exposure to perfluoroundecanoic
acid (PFUnDA) accelerates insulitis development in a mouse model of type 1 diabetes. Tox.
Report. 2016. 3:664–672.
Corsini E, Galbiati V, Papale A, Kummer E, Pinto A, Serafini MM, Guaita A, Spezzano R,
Caruso D, Marinovich M, Racchi M. Role of androgens in dhea-induced rack1 expression andcytokine modulation in monocytes. Immun Ageing. 2016 May 29. 13:20.
Corsini E, Galbiati V, Papale A, Kummer E, Pinto A, Guaita A, Racchi M. The role of HSP27 in
RACK1-mediated PKC activation in THP-1 cells. Immunol Res. 2016 Aug;64(4):940-50.
Galbiati V, Papale A, Kummer E, Corsini E. In vitro Models to Evaluate Drug-Induced
Hypersensitivity: Potential Test Based on Activation of Dendritic Cells. Front Pharmacol. 2016
Jul 12. 7:204.
Grozdanovic MM, Cavic M, Nešić A, Andjelković U, Akbari P, Smit JJ, Gavrovic-Jankulovic
MM. Kiwifruit cysteine protease actinidin compromises the intestinal barrier by disrupting tightjunctions. Biochim Biophys Act. 2016. 1860:516-526
Kwast L, Fiechter D, Kruijssen L, Bleumink R, Ludwig I, Bol-Schoenmakers M, Smit J, Pieters
R. Oral exposure to immunostimulating drugs results in early changes in innate immune
parameters in the spleen. J Immunotoxicol. 2016 Apr. 4:1-13.
Mihajlovic L, Radosavljevic J, Nordlund E, Krstic M, Bohn T, Smit J, Buchert J, Cirkovic
Velickovic T. Peanut protein structure, polyphenol content and immune response to peanut
proteins in vivo are modulated by laccase. Food Funct. 2016. 7:2357-2366
Papale A, Kummer E, Galbiati V, Marinovich M, Galli CL, Corsini E. Understanding chemicalallergen potency: role of NLRP12 and Blimp-1 in the induction of IL-18 in humankeratinocytes. Arch Toxicol. 2016 Sep 1.
Poland M, Ten Klooster JP, Wang Z, Pieters R, Boekschoten M, Witkamp R, Meijerink J.
Docosahexaenoyl serotonin, an endogenously formed n-3 fatty acid-serotonin conjugate has
anti-inflammatory properties by attenuating IL-23-IL-17 signaling in macrophages. Biochim
Biophys Acta. 2016 Sep 20. S1388-1981(16):30249-9.
Weldingh NM, Jorgensen L, Becher R, Holme JA, Bodin J, Nygaard UC, Bolling AK.
Bisphenol A Is More Potent than Phthalate Metabolites in Reducing Pancreatic Beta-Cell
Function. BioMed Research International 2017. vol. 2017.
Zucca E, Corsini E, Galbiati V, Lange-Consiglio A, Ferrucci F. Evaluation of amniotic
mesenchymal cell derivatives on cytokine production in equine alveolar macrophages: an invitro approach to lung inflammation. Stem Cell Res Ther. 2016 Sep 20. 7(1):137.
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Immunotoxicology Specialty Section

Recent Immunology Publications:
Methods/Models
Corsini E, Ozgen S, Papale A, Galbiati V, Lonati G, Fermo P, Corbella L, Valli G, Bernardoni V,
Dell'Acqua M, Becagli S, Caruso D, Vecchi R, Galli CL, Marinovich M. Insights on wood
combustion generated proinflammatory ultrafine particles (UFP). Toxicol Lett. 2017 Jan 15.
266:74-84.
Gennari CG, Franzè S, Pellegrino S, Corsini E, Vistoli G, Montanari L, Minghetti P, Cilurzo F.
Skin Penetrating Peptide as a Tool to Enhance the Permeation of Heparin through Human
Epidermis. Biomacromolecules. 2016 Jan 11. 17(1):46-55.
JanssenDuijghuijsen LM, Keijer J, Mensink M, Lenaerts K, Ridder L, Nierkens S, Kartaram
SW, Verschuren MC, Pieters RH, Bas R, Witkamp RF, Wichers HJ, van Norren K Adaptationof exercise-induced stress in well-trained healthy young men. Exp Physiol. 2016 Nov 3.
Knipping K, van Roest M, Kruijssen L, Smits M, Teunis M, Cox L, de Jong N, Simons PJ,
Boon L, Teshima R, Gros M, Kegler D, Garssen J, Knippels LM, Pieters R. Intra- and interlaboratory validation of an innovative huFcεRIα-RBL-2H3 degranulation assay for in vitro
allergenicity assessment of whey hydrolysates. Toxicol In Vitro. 2016 Jun. 33:29-34.
Papadopoulou E, Sabaredzovic A, Namork E, Nygaard UC, Granum B, Haug LS. Exposure of
Norwegian toddlers to perfluoroalkyl substances (PFAS): the association with breastfeeding
and maternal PFAS concentrations. Environ Int. 2016 Sep. 94:687-94.
Te Velde AA, Bezema T, van Kampen AH, Kraneveld AD, 't Hart BA, van Middendorp H, HackEC, van Montfrans JM, Belzer C, Jans-Beken L, Pieters RH, Knipping K, Huber M, Boots AM,
Garssen J, Radstake TR, Evers AW, Prakken BJ, Joosten I. Embracing Complexity beyond
Systems Medicine: A New Approach to Chronic Immune Disorders. Front Immunol. 2016 Dec.
12;7:587.
Reviews/Books/Commentaries
Bøgh KL, van Bilsen J, Głogowski R, López-Expósito I, Bouchaud G, Blanchard C, Bodinier
M, Smit J, Pieters R, Bastiaan-Net S, de Wit N, Untersmayr E, Adel-Patient K, Knippels L,
Epstein MM, Noti M, Nygaard UC, Kimber I, Verhoeckx K, O'Mahony L. Current challenges
facing the assessment of the allergenic capacity of food allergens in animal models. Clin
Transl Allergy. 2016 Jun 16. 6:21. Review.
Galbiati V, Papale A, Marinovich M, Gibbs S, Roggen E, Corsini E. Development of an in vitro
method to estimate the sensitization induction level of contact allergens. Toxicol Lett. 2017
Feb 8. S0378-4274(17)30047-4.
Kavasi RM, Berdiaki A, Spyridaki I, Corsini E, Tsatsakis A, Tzanakakis G, Nikitovic D. HA
metabolism in skin homeostasis and inflammatory disease. Food Chem Toxicol. 2017 Mar.
101:128-138. Review.

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Recent Immunology Publications:
Reviews/Books/Commentaries, cont.
Smit J, de Zeeuw-Brouwer M, van Roest M, de Jong G, van Bilsen J. Evaluation of thesensitizing potential of food proteins using two mouse models. Tox Letters 2016. 262: 62-69.
Smit JJ, Noti M, O’Mahony L. The use of animal models to discover immunologicalmechanisms underpinning sensitization to food allergens. Review. Drug Discov. Today Dis.
Models, in press.

Important Dates and Times

Immunotoxicology Student/Postdoctoral Mentoring Event
Monday, March 13
4:30-5:30pm
Key Ballroom 9, Hilton Baltimore,
Immunotoxicology Meeting/Reception
Monday, March 13
6:00-7:30pm
Key Ballroom 9, Hilton Baltimore,