第 81 回 日本循環器学会学術集会

13OE-398

The First Experience of Cyanoacrylate-based Embolization for Incompetent Great Saphenous Veinsin Japan

Impact of Peak Systolic Velocity in the CommonFemoral Artery on the Restenosis Following Stenting in the Femoropopliteal Artery

Naoki Sakakibara 1 、Rie Yoshida 2 、Tomohiro Imai 2 、
Kan Kajimoto 3 、Atsushi Amano 3

Koji Yanaka 1 、Osamu Iida 1 、Masashi Fujita 1 、Masaharu Masuda 1 、Shin Okamoto 1 、Takayuki Ishihara 1 、Kiyonori Nanto 1 、Takashi Kanda 1 、Akihiro Sunaga 1 、Takuya Tsujimura 1 、Shota Okuno 1 、Yasuhiro Matsuda 1 、Takuya Ohashi 1 、Hiroyuki Kawai 1 、Aki Tsuji 1 、
Masaaki Uematsu 1

1:Department of Cardiovascular Surgery, Edogawa Hospital,
Tokyo、2:Tokyo Vascular and Vein Clinic, Tokyo、3:Department of
Cardiovascular Surgery, Juntendo University School of Medicine,Tokyo

Objective: To evaluate the safety and eﬀectiveness of n-

1:Kansai Rosai Hospital Cardiovascular Center, Amagasaki

butyl cyanoacrylate (NBCA) endovenous closure of incom-Background: This study sought to investigate the impact

petent great saphenous veins (GSVs) in Japan.Method: In-of post procedural peak systolic velocity (PSV) in the com-competent 20 of GSVs were occluded by NBCA bolus injec-

mon femoral artery (CFA) on restenosis occurrence following

tions under ultrasound guidance without the use of perive-

femoropopliteal (FP) stenting. Method: We retrospectively

nous tumescent anesthesia or graduated compression stock-

analyzed a single-center database including 291 consecutive

Maximum GSV diameter was 12.6 ± 4.6cm.

4Fr

FP lesions from 246 patients who underwent FP stenting andcatheter was introduced near the saphenofemoral junction,

post procedural duplex ultrasound between January 2011

and NBCA was injected by 0.03mL/cm with continuousand December 2013. Multivariate analysis was performed tocatheter drawback by 2cm/sec.

Venous Clinical Sever-determine whether PSV was independently associated with

ity Score (VCSS), Aberdeen Varicose Vein Questionnaire

the restenosis occurrence. Results: Primary patency was(AVVQ) and duplex ultrasound evaluations were performed

70% at 1year and 59% at 2 years. Median PSV in the CFA

after 1 week and 3 months. Result: NBCA was injected by

was 114.7 cm/s. In multivariate analysis, PSV<115cm/s

1.3 ± 0.3 mL, and overall injection time was almost 20 sec.

was an independent predictor for restenosis occurrence (Ta-There was no major complication except phlebitis in 1 (5%)ble). Conclusion: PSV in the CFA following stenting in theand skin pigmentation in 1 (5%). Complete occlusion of theFP was independently associated with restenosis occurrence.

ings.

treated GSVs was confirmed up to 3 months by duplex ultrasound in all patients with suﬃcient NBCA polymerization.

[Keywords] peripheral vascular disease / ultrasound

VCSS improved in all patients from 4.9 ± 1.7 to 1.0 ± 1.5(p<.001), and AVVQ also improved from 8.2 ± 3.8 to 2.2 ±
2.3 (p<.001) at three months. Conclusion: The first clinicaluse of NBCA in Japan for endovenous closure of incompetent GSVs proved to be feasible, safe and eﬀective. Further
study is necessary to elucidate the long-term results.
[Keywords] veins / occlusion▲ TOP

Oral Presentation (English)

OE-397