API、AVI原著論文 リスト
資料NO

施 設 名

1

埼玉医大 代謝内科

232024/5/21
題名誌

著 者

リンク先

秋山義隆、久野裕輝、早川尚雅、重藤誠、枡澤政広、岡部正、松田昌文

http://jglobal.jst.go.jp/public/20090422/201002222920778530

名

２型糖尿病患者のオシロメトリック血圧測定による血管指標とFMD,IMTとの比較

Progress in Medicine 30:2003-2007, 2010.

Advanced Industrial Science
Non-invasive assessment of arterial stiffness using oscillometric blood pressure measurement （オシロメトリッand Technology (AIST )ク血圧計を用いた動脈スティフネス評価方法）(国）産業技術総合研究所

BioMedical Engineering OnLine 2012,
11:6

Hidehiko Komine*, Yoshiyuki Asai, Takashi Yokoi and MutsukoYoshizawa

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359259/

A computational model of the cardiovascular system coupled with an upper-arm oscillometric cuff and its
application to studying the suprasystolic cuff oscillation wave, concerning its value in assessing arterialstiffness （上腕オシロメトリックカフに連結された心血管系の計算モデルと、動脈硬度の評価におけるsuprasystricカフの振動波の研究応用)

Computer Methods in Biomechanics andBiomedicalEngineering

Fuyou Liang a , Shu Takagi a b , Ryutaro Himeno c & Hao Liu d

https://www.ncbi.nlm.nih.gov/pubmed/21916678

Association of estimated central blood pressure measured non-invasively
with pulse wave velocity in patients with coronary artery disease （冠動脈疾患患者における非侵襲的に測定された推定中枢血圧と脈波伝播速度との関連）

IJC Heart & Vasculature 8 (2015) 52–54

Daisuke Sueta a, Eiichiro Yamamoto a, ⁎, Tomoko Tanaka b,
Yoshihiro Hirata a, Kenji Sakamoto a, Kenichi Tsujita a,
Sunao Kojima a, Koichi Nishiyama b, Koichi Kaikita a, Seiji
Hokimoto a, Hideaki Jinnouchi b, Hisao Ogawa a

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5497261/

International Journal of CardiologyAvailable online 17 March 2015

Daisuke Suetaa, Eiichiro Yamamotoa, , , Tomoko Tanakab,
Yoshihiro Hirataa, Kenji Sakamotoa,
Kenichi Tsujitaa, Sunao Kojimaa, Koichi Nishayamab, Koichi
Kaikitaa, Seiji Hokimotoa, Hideaki Jinnouchib,Hisao Ogawa

https://pubmed.ncbi.nlm.nih.gov/25897917/

Masaki Okamoto1* , Fumiaki Nakamura1, Terunaga Musha2 andYasuki Kobayashi1

https://www.ncbi.nlm.nih.gov/pubmed/27821070(国研）理化学研究所

4Kumamoto University
熊本大学循環器内科
The accuracy of central blood pressure waveform by novel mathematical transformation of non-invasivemeasurement （非侵襲的測定から新しい数学的変換によってえられる中心血圧波形の精度）

56The University of Tokyo
東京大学公衆衛生学教室

Association between novel arterial stiffness indices and risk factors of cardiovascular disease（新しい動脈硬化指数と心血管疾患の危険因子との関連）

7Tohoku University
北大学内部障害

Arterial Stiffness Measured with the Cuff Oscillometric Method Is Predictive of Exercise Capacity in Patients
Yasushi Tazawa,1 Nobuyoshi Mori,1 Yoshiko Ogawa,1 Osamu Ito1Tohoku J. Exp. Med., 2016, 239,O 1s2c7ilwith Cardiac Diseases（カフオシロメトリック法で測定された動脈の硬さは、心臓病患者の運動耐容能の予測値でandlo1m34etrある）
Masahiro Kohzuki1

東Comparison of the clinical significance of single cuff-based arterial stiffness parameters with that of thecommonly used parameters（単一カフに基づく動脈硬化パラメータと一般的に使用されるパラメータとの臨床的意義の比較）

8

BMC Cardiovascular Disorders (2016)
16:211

Journal of Cardiology xxx (2016) xxx–xxx

Shunsuke Komatsu (MD), Hirofumi Tomiyama (MD, FJCC) *,Kazutaka Kimura (MD),Chisa Matsumoto (MD), Kazuki Shiina (MD, FJCC), Akira
Yamashina (MD, FJCC)

https://www.jstage.jst.go.jp/article/tjem/239/2/239_127/_articlehttps://www.journal-of-cardiology.com/article/S09145087(16)30119-8/pdf

Tokyo Medical University
東京医科大循環器内科
Increase in the Arterial Velocity Pulse Index of Patients with Peripheral Artery Disease 血管障害の評価にAVIを使用する際は、末梢動脈疾患（PAD＝peripheral arterial disease）が存在する可能性を考慮しなければならな Pulse 2017;5:154–160
い。

910Shanghai Ninth People’s
Non-Invasive Assessment of Early Atherosclerosis Based on New Arterial Stiffness Indices Measured with anHospital, Shanghai Jiao Tong
Upper-Arm Oscillometric Device（上腕オシロメトリック装置を用いて測定した新しい動脈硬さ指数に基づく早期University 上海交通大学第アテローム性動脈硬化症の非侵襲的評価）
九病院

Tohoku J. Exp. Med., 2017, 241, 26327E0a

Naotaka Murata Kazuki Shiina Jun Yamashita Nobuhiro Tanaka
Taishiro Chikamori Akira Yamashina Hirofumi Tomiyama

Yaping Zhang,1,* Ping Yin,1,* Zuojun Xu,1 Yushui Xie,1 ChangqianWang,1Yuqi Fan,1 Fuyou Liang2 and Zhaofang Yin1

https://www.ncbi.nlm.nih.gov/pubmed/29761091

https://www.jstage.jst.go.jp/article/tjem/241/4/241_263/_articleSuccessful prediction of cardiovascular risk by new non-invasive vascular indexes using suprasystolic cuff
oscillometric waveform analysis（収縮期圧以上のカフオシロメトリック波形解析を用いた新しい非侵襲的血管指 Journal of Cardiology 69 (2017) 30–37
標による心血管リスクの予測）

Rie Sasaki-Nakashima (MD)a,b, Tabito Kino (MD)a,b, Lin Chen(MD)a,b, Hiroshi Doi (MD)a,b,
Shintaro Minegishi (MD, PhD)a,b, Kaito Abe (MD, PhD)a,b,
Teruyasu Sugano (MD, PhD)a,b,
Masataka Taguri (PhD)c, Tomoaki Ishigami (MD, PhD)a,b,*

12

New non-invasive indexes of arterial stiffness are significantly correlated with severity and complexity ofClinical and Experimental Hypertension
coronary atherosclerosis. 動脈硬化の新しい非侵襲性指数は、冠動脈アテローム性動脈硬化症の重症度および2018 May 8:1-7.
複雑さと有意に相関する。

DoiH1,2, Ishigami T1,2, Nakashima-Sasaki R1,2, Kino T1,2, Chen
L1,2, Arakawa K1,2, Teranaka S1,2, Minegishi S1,2, Abe K1,2,Ishikawa T1,2, Sugano T1,2, Tamura K1

https://pubmed.ncbi.nlm.nih.gov/29737880/

13

Arterial Velocity Pulse Index as a Novel Marker of Atherosclerosis Using Pulse Wave Analysis on HighSensitivity Troponin T in Hypertensive Patients(高血圧患者の高感度トロポニンTと脈波解析を応用したアテローム性動脈硬化症のマーカーとしての速度脈波指標AVI)Cardiol Res. 2017;8(2):36-43

Takashi Hitsumotohttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421484/

Relationships between the arterial velocity pulse index as a novel marker of atherosclerosis and biomarkers ofcardiac or renal condition in patients with type 2 diabetes mellitus 2型糖尿病患者におけるアテローム性動脈硬化症の新規マーカーである動脈速度パルス指数と心臓または腎臓のバイオマーカーの関係

Diabetology International
pp 1–8 2017

Takashi Hitsumotohttps://link.springer.com/article/10.1007/s13340-017-0329-8

11
Yokohama City University
横浜市立大学循環器内科

14

Hitsumoto Medical Clinic
ひつもと循環器内科ＣＬhttps://www.journal-of-cardiology.com/article/S09145087(16)30121-6/fulltext

15161718

Harumidai Clinic
晴海台ＣＬ 内科

Nagasaki University
長崎大学先進予防医学

Fukuoka University
福岡大学循環器内科

2022232425

Cardiol Res. 2019;10(3):142-149

Takashi Hitsumotohttps://pubmed.ncbi.nlm.nih.gov/31236176/

Effects of Long-term Physical Training on the Bearers of a
Float during the Nagasaki Kunchi Festival （長崎くんち祭りにおける山車の担い手に対する長期練習の効果）

Intern Med 56: 11-16, 2017

Shigemori Shibata 1, Hiroaki Kawano 2 and Koji Maemura2

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5313419/

Physiol Rep, 6 (5), 2018, e13574,
https://doi.org/10.14814/phy2.13574

Ryota Kobayashi1 , Soichiro Iwanuma2, Nobuyuki Ohashi2 &Takeo Hashiguchi2

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827568/

Screening Validity of Arterial Pressure-Volume Index and Arterial Velocity-Pulse Index for PreclinicalAtherosclerosis in Japanese Community-Dwelling Adults: the Nagasaki Islands Study（日本の地域社会に暮ら J Atheroscler Thromb. 2018 Feb 3. doi:
す成人における症状発現前のアテローム性動脈硬化症のスクリーニングに対する動脈圧容積指数と動脈速度脈 10.5551/jat.43125. [Epub ahead of print]
波指数の有効性）

Hirotomo Ymanashi

https://www.ncbi.nlm.nih.gov/pubmed/29398680

Association of Arterial Pressure Volume Index With the Presence of Significantly Stenosed Coronary Vessels（有意に狭窄した冠状動脈の存在と動脈圧容積指数との関連）

Takashi Uedaa, Shin-ichiro Miuraa, b, d, Yasunori Suematsua,
Yuhei Shigaa, Takashi Kuwanoa,
Makoto Sugiharaa, Amane Ikea, Atsushi Iwataa, Hiroaki
Nishikawaa, Kanta Fujimia, c,

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931806/Cardiac rehabilitation in patients with cardiovascular disease leads
various hemodynamic parameters obtained using simple non-invasive
IJC Heart & Vasculature 17 (2017) 23–29
tests to their appropriate levels 心臓血管疾患の患者の心臓リハビリテーションは、簡便な非侵襲的試験器を用いて得られた様々な血行動態パラメータを適切なレベルに導く

Makito Futami a,1, Kanta Fujimi a,b,1, Takashi Ueda a,
TakuroMatsuda b, Masaomi Fujita b, Kouji Kainob,
Maaya Sakamoto a, Tomoe Horita c, Rie Koyoshi a, Tadaaki
Arimura a, Yuhei Shiga a, Takashi Kuwano a,
Ken Kitajima a, Keijiro Saku a,d, Shin-ichiro Miura a,d, ⁎https://www.ncbi.nlm.nih.gov/pubmed/29201997

Effect of mangosteen pericarp extract on skin moisture and arterial stiffness:
Placebo-controlled double-blinded randomized clinical trial マンゴスチン果皮抽出物が皮膚の水分および動脈 Glycative Stress Research
硬化に及ぼす影響：プラセボ対照二重盲検ランダム化臨床試験

Kazuhiro Maejima 1), Rei-ichi Ohno 2), Ryoji Nagai 2, 3), Shuji
Nakata 4)

http://www.toukastress.jp/webj/article/2018/GS18-15.pdf

Seasonal variation of novel arterial stiffness indexes in Japanese hypertensive patients 日本人高血圧患者にClinical and Experimental Hypertension
おける新しい動脈硬化指数の季節変動

Toshihiro Kita & Kazuo Kitamura

https://www.ncbi.nlm.nih.gov/pubmed/30409046/

榛沢 和彦, 伊倉 真衣子, 岡本 竹司, 大久保 由華, 土田 正則, 中島 孝, 品田 恭子, 岡村 治

https://ci.nii.ac.jp/naid/130007709115/

Teikyo University of Science
New indices of arterial stiffness measured with an upper-arm oscillometric device in active versus inactive
帝京科学大学運動生理
women (若い女性における運動習慣の有無と上腕オシロメトリック装置で測定された新しい動脈硬化の指数)

1921

Clinical Significance of Arterial Velocity Pulse Index in Patients With Stage B Heart Failure With Preserved
Ejection Fraction 駆出率が維持されたB期心不全患者における動脈速度パルス指数の臨床的意義

Nippon Shinyaku Co., Ltd.
日本新薬・東海大学

University of Miyazaki
宮崎大学循環器内科Niigata University
Relationship between high intensity transient signals at common carotid artery by paste type probe and新潟大学医歯学総合研究科
cerebro-cardiovascular disease in the residents in the area of Chu-etsu Oki Earthquake新潟県中越沖地震被 Article in Neurosonology 32(2):46-52 ·先進血管病・塞栓症治療・予災地域一般住民における貼り付け型プローブを用いた総頸動脈のhigh intensity transient signalsと脳・心血管疾 January 2019
防講座|新潟大学医歯学総合
患との関連
研究科呼吸循環外科

Yokohama City University
横浜市立大学循環器内科

Successful prediction of clinical outcomes using arterial velocity pulse index, a new non-invasive vascularindex, in Japan 新しい非侵襲的血管指標である動脈速度脈波指標（AVI)は臨床転帰を良好に予測する

Department of Cardiology,
The First Affiliated Hospital, Roles of arterial pressure volume index and arterial velocity pulse index trajectories in risk prediction inChengdu Medical College hypertensive patients with heart failure with preserved ejection fraction
成都医療大学26

School of Naval
Architecture, Ocean & Civil
Theoretical Method and Clinical Experiments for Estimating Arterial Stiffness Based on Upper-Arm CuffEngineering, Shanghai Jiao
Oscillometric WaveTong University
上海交通大学27

Department of Cardiology,
Kurume University MedicalCenter,Kurume
久留米大学

28

West China Hospital, Sichuan
New indices of arterial stiffness correlate with disease severity and mid-term prognosis in acuteUniversity
decompensated heart failure
四川医学院

29J Clin Med Res. 2016;8(8):598-604

長崎県農林技術開発セン
ター 食品加工研究室

Increased arterial velocity pulse index is an independent factor related to skeletal muscle mass reduction andtissue damage in patients with cardiovascular disease

摘果ミカンと緑茶三番茶葉を混合揉捻して製造した発酵茶摂取が動脈血管の柔軟性に及ぼす影響
ム化二重盲検プラセボ対照並行群間比較試験―

Vascular Failure 2019; 3(2): 43-50

Rie Sasaki-Nakashima1), Tomoaki Ishigami1), Tabito Kino1), Sae
Teranaka-Saigo1), Lin Chen1), Hiroshi Doi1),
Michiko Sugiyama1), Shintaro Minegishi1), Kentaro Arakawa1),
Kaito Abe1), Hiromichi Wakui1),
Kengo Azushima1), Kouichi Tamura1)2) and Kazuo Kimura1)2)

JournalClinical and Experimental Hypertension
Volume 42, 2020 - Issue 5

Jindong Wan 1 2, Sen Liu 1 2, Yi Yang 1 2, Dan Wang 1 2, Fei Ran
1 2, Siwei Xia 1 2, Shuangtao Ma 3, Jixin Hou 1 2, Peng Zhou 12, Yun Sun 4, Peijian Wang 1 2

ZHANG Xujie1, ZHANG Yaping2, YIN Zhaofang3, QIN Kairong4,中国医疗设备 2018, Vol. 33 Issue (4): LIANG Fuyou1
22-28 DOI: 10.3969/j.issn.16741633.2018.04.006
Hypertension Research (2020) 43:534–542

Haruhito Harada1 ,Hisao Ikeda2 , Yasuhiro Nishiyama1 , Hiroshi
Niiyama1 , Atsushi Katoh1 , Hisashi Kai1

Junteng Zhou, Yushu Wang, Yizhou
Internal and Emergency Medicine Official Feng, Xiaojing Chen & Qing Zhang
Journal of the Italian Society ofInternal Medicine―ランダ宮田 裕次1） 田 中 隆2） 松井 利郎3） 大曲 勝久4） 湯浅
Jpn Pharmacol Ther（薬理と治療）vol. 49 正洋4） 山本咲暁子4） 田中 一成4）
no. 1 2021

https://www.jstage.jst.go.jp/article/vascfail/3/2/3_43/_article/-char/en

https://www.tandfonline.com/doi/full/10.1080/10641963.2019.
1705319

http://cs.chinacmd.org/zgylsb/CN/abstract/abstract3246.shtml

https://www.nature.com/articles/s41440-020-0404-6

https://link.springer.com/article/10.1007/s11739-020-02486-x

http://www.pieronline.jp/content/article/0386-3603/49010/63

30Juntendo University
順天堂大学

Arterial Stiffness Index and Exercise Tolerance in Patients Undergoing Cardiac Rehabilitation

Int Heart J Advance Publication

31Teikyo
University of Science
帝京科学大学

Effect of aerobic exercise training frequency on arterial stiffness in middle-aged and elderly females

The Journal of Physical Therapy Science32

Kanazawa University
金沢大学

Relationships between muscle sympathetic nerve activity and novel indices of arterial stiffness using single
oscillometric cuff in patients with hypertension

Physiological Reports. 2022;10:e15270.

Kei Fujiwara 1, Kazunori Shimada 1 2 3, Miho Nishitani-Yokoyama
1 2, Mitsuhiro Kunimoto 1, Tomomi Matsubara 1, Rie Matsumori 1,Abidan Abulimiti 1 3, Tatsuro Aikawa 1, Shohei Ouchi 1, Megumi
Shimizu 1, Kosuke Fukao 1, Tetsuro Miyazaki 1, Akio Honzawa 2,Miki Yamada 2, Masakazu Saitoh 4, Tomoyuki Morisawa 4,Tetsuya Takahashi 4, Hiroyuki Daida 1 3 4, Tohru Minamino 1 5
Ryota Kobayashi, PhD1)*, Kenji Asaki2), Takeo Hashiguchi,PhD3),
Hideyuki Negoro, MD, PhD4, 5)
Hiroyuki Sugimoto1 | Takuto Hamaoka1,2 | Hisayoshi Murai1,3 |Tadayuki Hirai1 |Yusuke Mukai1 | Takashi Kusayama1 | Shinichiro Takashima1 |Takeshi Kato1 |Shigeo Takata3 | Soichiro Usui1 | Kenji Sakata1 | Masa-AkiKawashiri1 |Masayuki Takamura1
Jingyun Hu1†, Min Liu2†, Ruoyu Yang3†, Liyan Wang3, Leichao
Liang3, Yuanyuan Yang3, Shihao Jia3, Ruiyi Chen3,
Qianle Liu3, Yu Ren3, Lei Zhu2 and Ming Cai4*

https://pubmed.ncbi.nlm.nih.gov/33731517/

https://pubmed.ncbi.nlm.nih.gov/35527837/

https://pubmed.ncbi.nlm.nih.gov/35587702/

33

Shanghai University ofMedicine & Health Sciences
Effects of high ‑intensity interval training on improving arterial stiffness in Chinese female university students
Affiliated Zhoupu
with normal weight obese a pilot randomized controlled trialHospital
上海大学

J Transl Med. 2022 Feb 2;20(1):60.

34

Department of
Cardiovascular Medicine,Kagoshima City Hospital,
Kagoshima, Japan
鹿児島市民病院

Noninvasive Assessment of Arterial Stiffness Using Oscillometric Methods: baPWV, CAVI, API, and AVI

The official journal of the Japan
Atherosclerosis Society andthe Asian Pacific Society ofAtherosclerosis and Vascular Diseases

35

Department of Ultrasound,First Hospital of Shanxi
Medical University
山西医科大学第一医院

Relationship of arterial stiffness and centralhemodynamics with cardiovascular risk inhypertension

American Journal of Hypertension

Lin Jin,Jianxiong Chen,Mengjiao Zhang,Lei Sha,Mengmeng
Cao,Lanyue Tong,Qingqing Chen,Cuiqin Shen,Lianfang Du,Zhaojun
Li,Liping Liu

https://pubmed.ncbi.nlm.nih.gov/36645322/

Upper-Arm SBP Decline Associated with Repeated Cuff-Oscillometric Inflation Significantly Correlated with
the Arterial Stiffness Index

Journal of Clinical Medicine

Noriyuki Kawaura 1, Rie Nakashima-Sasaki 1, Hiroshi Doi 2,Kotaro Uchida 1, Takuya Sugawara 1, Sae Saigo 3,Kaito Abe 1,Kentaro Arakawa 1, Koichi Tamura 1, Kiyoshi Hibi 4 and Tomoaki
Ishigami 1,*

https://pubmed.ncbi.nlm.nih.gov/36362683/

https://pubmed.ncbi.nlm.nih.gov/35109880/

Masaaki Miyata
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143778/

36

Yokohama City University
横浜市立大学循環器内科

37

Shanghai General Hospital,

Relative contributions of arterial stiffness to cardiovascular disease risk score in Chinese women inframingham and China-PAR model

Frontiers in Cardiovascular Medicin

38

Faculty of Medicine, Nara
Medical UniversityA Workcation Improves Cardiac Parasympathetic Function during Sleep to Decrease Arterial Stiffness inWorkers

Healthcare 2022, 10, 2037.
https://doi.org/10.3390/healthcare10102
037

Hideyuki Negoro 1,2,*,† and Ryota Kobayashi 3,†

39

Nippon Shinyaku Co., Ltd.,

Effects of hot water extract of mangosteen pericarp on vascular function:Re-analysis focusing on factors
affecting vascular function.

Glycative Stress Research

Kenjiro Hayashi, Aoi Kiyokawa, Kazuhiro Maejima

40

Hitsumoto Medical Clinic
ひつもと循環器内科ＣＬ

Relationships Between Arterial Pressure-Volume Index and Cardiovascular Disease Biomarkers in Patients
With Hypertension

J Clin Med Res. 2022;14(6):229-236

Takashi Hitsumotohttps://pubmed.ncbi.nlm.nih.gov/35836723/

41Shanghai Jiao Tong
UniversityThreshold values of brachial cuff-measured arterial stiffness indices determined by comparisons with thebrachial–ankle pulse wave velocity: a cross-sectional study in the Chinese population

Front Cardiovasc MedXujie Zhang1, Yumin Jiang2, Fuyou Liang1,3* and Jianping Lu2*

https://pubmed.ncbi.nlm.nih.gov/37522090/

Lin Jin1,2, Lingheng Wu2,3, Jianxiong Chen2,3, Mengjiao Zhang2,Jiali Sun2, Cuiqin Shen2, Lianfang Du4, Xiaoyin She5 and Zhaojun
Li2,4

https://pubmed.ncbi.nlm.nih.gov/37798630/

Lin Jin1,2, Jianxiong Chen3, Lingheng Wu3, Mengjiao Zhang1,Jiali
Sun1, Cuiqin Shen1, Lianfang Du4, Dingqian Wang5and haojun
Li1,4*

42

Shanghai University ofUncoupling of the center-to-periphery arterial stiffness gradient and pulse pressure amplification in viral
Traditional Chinese Medicine pneumonia infection

BMC Infectious Diseases

43

独立行政法人労働者健康安
全機構労働安全衛生総合研 地場トラックドライバーの職場における血圧上昇要因の検討究所

令和４年度労災疾病臨床研究事業費補助金「過労死等の実態解明と防止対策に関研究分担者 松元 俊する総合的な労働安全衛生研究」
分担研究報告書（疫学研究）

https://pubmed.ncbi.nlm.nih.gov/37396573/

https://pubmed.ncbi.nlm.nih.gov/36292483/
https://www.jstage.jst.go.jp/article/gsr/9/3/9_170/_article/char/ja/

https://records.johas.go.jp/rep76.pdf

Shuai Liu 1, Fang Chao Liu 2, Jian Xin Li 2, Ke Yong Huang

44

Nanjing Medical University

Association between Fruit and Vegetable Intake and Arterial Stiffness_ The China-PAR Project

Biomed Environ Sci.

2, Xue Li Yang 3, Ji Chun Chen 2, Jie Cao 2, Shu Feng Chen
2, Jian Feng Huang 2, Chong Shen 4, Xiang Feng Lu 5, Dong
Feng Gu 6

https://pubmed.ncbi.nlm.nih.gov/38199223/