Cresol red solution
Hayashi Pure Chemical Ind.,Ltd.
Date of issue: 3/1/2021

Revision date: 8/21/2024

SDS code: ZA-18

Version: 02

Safety Data Sheet
1. Chemical product and company identification
Product nameSDS code::

Cresol red solution
ZA-18

Company/undertaking:
identification
HAYASHI PURE CHEMICAL IND.,LTD.
Address : 3-2-12 Uchihiranomachi, Chuo-ku, Osaka, Osaka, Japan
Telephone : 06-6910-7305
E-mail : shiyaku_kikaku@hpc-j.co.jp
URL : https://www.hpc-j.co.jp/Emergency number
Recommended use
Restrictions on use:::06-6910-7305
For research and experimental use only.
Do not use on a human body or for animal medicines, foods, householdproducts, cosmetics, etc.

2. Hazards identification
GHS classification
Physical hazards

Health hazards

Desensitized explosives
Explosives
Flammable gases
AerosolOxidizing gases
Gases under pressure
Flammable liquids
Flammable solids
Self-reactive substances andmixtures
Pyrophoric liquids
Pyrophoric solids
Self-heating substances andmixtures
Substances and mixtures which incontact with water emit flammablegases
Oxidizing liquids
Oxidizing solids
Organic peroxides
Corrosive to metals
Acute toxicity (oral)
Acute toxicity (dermal)
Acute toxicity (inhalation:gas)
Acute toxicity (inhalation:vapors)
Acute toxicity (inhalation:dust/mist)
Skin corrosion/irritation
Serious eye damage/eye irritation
Respiratory sensitization
Skin sensitization
Germ cell mutagenicity
Carcinogenicity
Reproductive toxicity
Specific target organ toxicity (singleexposure)classification not possibleclassification not possible
No classification
classification not possible
No classification
No classification
classification not possible
No classification
classification not possibleclassification not possible
No classification
classification not possibleclassification not possibleclassification not possible
No classification
classification not possibleclassification not possibleclassification not possibleclassification not possibleclassification not possibleclassification not possibleclassification not possible
No classification
No classification
classification not possible
No classification
No classification
classification not possibleclassification not possible
No classification

1/7

Hayashi Pure Chemical Ind.,Ltd.

Cresol red solution
Revision date: 8/21/2024

Environmental
hazards

Specific target organ toxicity(repeated exposure)
Aspiration hazard
Hazardous to the aquatic
environment, short-term (acute)Hazardous to the aquatic
environment, long-term (chronic)
Hazardous to the ozone layer

SDS code: ZA-18

Version: 02

classification not possibleclassification not possibleclassification not possibleclassification not possibleclassification not possible

3. Composition/information on ingredients
Distinction of substance or mixture:

MixtureConcentration orConcentration range

Name

Kanpo number

FormulaCSCL no

ISHL noCAS RN

Cresol red

About 0.04％

C21H18O5S--

1733-12-6

Sodium hydroxide

About 0.004％

NaOH(1)-410

Existing
ChemicalSubstance

1310-73-2

Water

About 99.956％

H2O--7732-18-5

The above concentration or concentration range are not product specification.
All percentages listed in the above concentration or concentration range are wt%, unless otherwise specified.

4. First aid measures
First aid measures
First-aid measures after inhalation:

First-aid measures after skincontact:

First-aid measures after eye
contact:

First-aid measures after ingestion:

Remove person to fresh air and keep comfortable for breathing.
Get immediate medical advice/attention.
Remove/Take off immediately all contaminated clothing.
Gently wash with plenty of soap and water.
Get immediate medical advice/attention.
IF IN EYES: Rinse cautiously with water for several minutes. Remove
contact lenses, if present and easy to do. Continue rinsing.
Get immediate medical advice/attention.
Rinse mouth.
Get immediate medical advice/attention.

5. Fire fighting measures
Suitable extinguishing media
Unsuitable extinguishing media
Hazardous decomposition products
in case of fire
Firefighting instructions:::

Use proper extinguishing media depending on peripheral fire.
Do not use a heavy water stream.
In case of fire, product may produce irritative or toxic fumes/gases.

:

Protection during firefighting:If ignited, for the initial fire-fighting, cut off combustion sources, extinguishfire at a stroke using appropriate fire-extinguishers.
In the case of peripheral fire, quickly remove movable containers to safe
places.
If unable to be moved containers, sprinkle water to containers andsurrounding equipment, etc. to cool.
Wear appropriate fire-resistant clothing including self containedcompressed air breathing apparatus.

6. Accidental release measures
Personal Precautions, Protective Equipment and Emergency Procedures
General measures: Wear appropriate personal protective devices to prevent inhalation andcontact with eye, skin, and clothing, and never attempt to work on the lee.
Environmental precautions
Environmental precautions:

Avoid release to the environment.
Prevent entry to sewers and public waters.
2/7

Hayashi Pure Chemical Ind.,Ltd.

Cresol red solution
Revision date: 8/21/2024

SDS code: ZA-18

Version: 02

Methods and Equipment for Containment and Cleaning up
Methods for cleaning up: Clean up any spills as soon as possible, using an absorbent material tocollect it.
Collect leaking and spilled liquid in sealable containers as far as possible.
Wash out the spilled area with large amounts of water.

7. Handling and storage
Handling
Technical measures:

Precautions for safe handling:

Prevents handling of incompatible
substances or mixtures:

Storage
Storage conditions:

Store in a well-ventilated place, away from direct sunlight. Keep container
tightly closed and keep away from fire and heat sources.
Light shielding airtight container.

::

Comply with applicable regulations.
Cool and dark place:

Material used inpackaging/containers
Technical measures
Storage temperature

Work with appropriate personal protective equipment to prevent inhalationor contact to eyes, skin, and clothing.
Handle with care to prevent leakage, overflowing, or scattering, minimize
generation of mist or vapor, and thoroughly ventilate.
Do not eat, drink or smoke when using this product.
Thoroughly wash your hands and gargle after handling.
Ensure good ventilation of the work station.
Do not contact, breathe or swallow.
Avoid prolonged or repeated exposure.

8. Exposure controls / Personal protection equipment
Component name

Administration level (MHLW)

Exposure limits (JSOH)
Standard Value-Sodium hydroxide

Appropriate engineering controls

Protective equipment
Respiratory protection
Hand protection
Eye protection
Skin and body protection-JSOH OEL C
2 mg/m³: Cover up tightly the generation source at the handling place or install local
exhaust equipment or overall ventilation equipment. Install safety showers
and eye-fountains near a handling place. Clearly indicate the location.
: Protective mask
: Impervious protective gloves: Protective glasses (general glasses, glasses with side-shields, goggles): Impervious aprons, Impervious work clothing, Impervious long boots

9. Physical and chemical properties
Physical stateAppearance
ColorOdor
pH::
:
:
:

LiquidLiquid
reddish brown
characteristic odor

Melting point
Freezing point
Boiling point
Flash point
Auto-ignition temperature
Decomposition temperature
Flammability
Vapor pressure
Relative density
Density

::
:
:
:
:
:
::
:

No data available
No data available
No data available
No data available
No data available
No data available
No data available
No data available
No data available

7.1 （25℃）

1.00 g/cm³ （20℃）
3/7

Hayashi Pure Chemical Ind.,Ltd.

Cresol red solution
Revision date: 8/21/2024

Relative gas density
Solubility
Partition coefficient noctanol/water (Log Pow)
Explosive limits (vol %)Viscosity, kinematic
Particle characteristics:::

No data available
No data available
No data available:::

No data available
No data available
No data available

::
:
:
:
:

No data available
Stable under normal handling conditions.
No data available
Sunlight, Heat
No data available
Sulfur oxides

SDS code: ZA-18

Version: 0210. Stability and reactivity
Reactivity
Chemical stability
Possibility of hazardous reactions
Conditions to avoid
Incompatible materials
Hazardous decomposition
products

11. Toxicological information
The information in this section is based on the "GHS Classification Results" by NITE.
As a productAcute toxicity (oral)classification not possible
Acute toxicity (dermal)
classification not possible
Acute toxicity (inhalation)
vapors:classification not possible
Gases:classification not possible
dust, mist:classification not possible
Skin corrosion/irritation
No classification
Serious eye damage/irritation
No classification
Respiratory sensitization
classification not possible
Skin sensitization
No classification
Germ cell mutagenicity
No classification
Carcinogenicity
classification not possible
Reproductive toxicity
classification not possible
STOT-single exposure
No classification
STOT-repeated exposure
classification not possible
Aspiration hazard
classification not possible
Cresol red
Acute toxicity (oral)
Acute toxicity (dermal)
Acute toxicity (gas)Acute toxicity (vapour)
Acute toxicity (inhalation:dust/mist)
Skin corrosion/irritation
Serious eye damage/irritation
Respiratory sensitization
Skin sensitization
Germ cell mutagenicity
Carcinogenicity

No data available
No data available
No data available
No data available
No data available
No data available
No data available
No data available
No data available
No data available
No data available

Reproductive toxicity

No data available

STOT-single exposure

No data available

STOT-repeated exposure

No data available

Aspiration hazard

No data available

Sodium hydroxide
Acute toxicity (oral)
Acute toxicity (dermal)
Acute toxicity (gas)Acute toxicity (vapour)
Acute toxicity (inhalation:dust/mist)
Skin corrosion/irritation

classification not possibleclassification not possible
No classification
classification not possibleclassification not possible
Category 1
4/7

Hayashi Pure Chemical Ind.,Ltd.

Cresol red solution
Revision date: 8/21/2024

Sodium hydroxide
Serious eye damage/irritation
Respiratory sensitization
Skin sensitization
Germ cell mutagenicity
Carcinogenicity

Category 1classification not possible
No classification
No classification
classification not possible

Reproductive toxicity

classification not possible

STOT-single exposure

Category 1

STOT-repeated exposure

classification not possible

Aspiration hazard

classification not possible

Water
Acute toxicity (oral)
Acute toxicity (dermal)
Acute toxicity (gas)Acute toxicity (vapour)
Acute toxicity (inhalation:dust/mist)
Skin corrosion/irritation
Serious eye damage/irritation
Respiratory sensitization
Skin sensitization
Germ cell mutagenicityCarcinogenicity

No classification
No classification
No classification
No classification
No classification
No classification
No classification
No classification
No classification
No classification
No classification

Reproductive toxicity

No classification

STOT-single exposure

No classification

STOT-repeated exposure

No classification

Aspiration hazard

No classification

SDS code: ZA-18

Version: 02

12. Ecological information
The information in this section is based on the "GHS Classification Results" by NITE.
As a productHazardous to the aquatic environment, classification not possible
short-term (acute)Hazardous to the aquatic environment, classification not possible
long-term (chronic)
Persistence and degradability
No data available
Bioaccumulative potential
No data available
Mobility in soil
No data available
Ozone
classification not possible
Cresol red
Hazardous to Aquatic Environment Acute Hazard
Hazardous to Aquatic Environment Chronic Hazard
Persistence and degradability
Bioaccumulative potential
Mobility in soil
Hazardous to the ozone layer
Sodium hydroxide
Hazardous to Aquatic Environment Acute Hazard
Hazardous to Aquatic Environment Chronic Hazard
Persistence and degradability
Bioaccumulative potential
Mobility in soil
Hazardous to the ozone layer

No data available
No data available
No data available
No data available
No data available
No data available
Category 3
No classification
No data available
No data available
No data available
classification not possible
5/7

Hayashi Pure Chemical Ind.,Ltd.

Cresol red solution
Revision date: 8/21/2024

Water
Hazardous to Aquatic Environment Acute Hazard
Hazardous to Aquatic Environment Chronic Hazard
Persistence and degradability
Bioaccumulative potential
Mobility in soil
Hazardous to the ozone layer

SDS code: ZA-18

Version: 02

No classification
No classification
No data available
No data available
No data availableclassification not possible

13. Disposal considerations
Ecology - waste materials:

Contaminated container andpackaging:

With the detail information of the waste, subcontract its disposal to awaste disposer authorized by a Prefectural Governor.
Empty the packaging completely prior to disposal.
Empty containers should be taken for recycle, recovery or waste inaccordance with local regulation.

:
:
:
:

Not applicableNot applicableNot applicableNot applicable

:
:
:
:

Not applicableNot applicableNot applicableNot applicable

Marine pollutant:

Not applicable

Regulations in JapanRegulatory information by sea
Regulatory information by air
Special transport precautions:::

Not applicableNot applicable
When transporting, load containers so that they do not tip over,damage, drop or collapse. Make sure there is no leak in containers.

::

Not applicableNot applicable:

Designated Chemical Substances (Law Article 2, Paragraph 4,Enforcement Order Article 3-3)
Not applicable
Export Trade Control Ordinance appendix 1-16

14. Transport information
International Regulations
Transport by sea(IMDG)
UN-No. (IMDG)
Proper Shipping Name (IMDG)
Packing group (IMDG)
Transport hazard class(es) (IMDG)
Air transport(IATA)
UN-No. (IATA)
Proper Shipping Name (IATA)
Packing group (IATA)
Transport hazard class(es) (IATA)

15. Regulatory information
National law
Industrial Safety and Health Law
Japanese Poisonous andDeleterious Substances Control Law
Water Pollution Prevention Law
Fire Service Law
Foreign Exchange and Foreign
Trade Control Act
Waterworks Law::

Japanese Pollutant Release andTransfer Register Law (PRTR Law)
Labor Standards Act:::

Hazardous Substances (Act Article 4 paragraph 2), Standard for
Water Quality (Ministry Order No.101 of 2003)
Not applicableChemical Substances Causing Occupational Illnesses (Act Art.75,Para.2, Ordinance Attached Table 1-2, Item 4-1, MHLW Nortification
No.36 of 1978)

6/7

Hayashi Pure Chemical Ind.,Ltd.

Cresol red solution
Revision date: 8/21/2024

SDS code: ZA-18

Version: 02

16. Other information
Data sources:

Other information:

Handbook of 17524 Chemical Products, The Chemical Daily Co, Ltd.
International Chemical Safety Cards.
National Institute of Technology and Evaluation (NITE).
2020 Emergency Response Guidebook (ERG 2020).
The SDS is copyrighted material of Hayashi Pure Chemical Ind, Ltd.
This Safety Data Sheet is intended to be provided for business
operators who handle chemical substance products of the relevant
product and is not intended to assure safety in any way. The Safety
Data Sheet does not verify all the information on the applicablechemical substance in the present time. With the recognition in that
unknown danger constantly exists in the relevant chemical substance,
the product shall be used in the principle of self-responsibility of theuser with the highest priority to safety from transport and unpacking todisposal. When the relevant chemical substance is used, the user
him/herself shall collect safety information and shall investigate laws
and regulations at the place, organizations, countries, etc. where thesubstance is actually used and give the highest priority to them. TheCompany shall take no responsibility for investigating state and local
regulations and the user shall handle this problem on his/her own
responsibility. In the event that SDS in Japanese and SDS translated
into other languages exist, the document described in Japanese isprior to all other documents whether or not there is any difference incontents, and documents in other languages shall be references.

7/7