Program
Thursday, June 7
Opening Remarks:
9:30
Sidonia Fagarasan, Chair, Program Committee
Session I: Fundamental aspects of immunology: Antigenicity
Chair: T. Akiyama and M. Lafaille
9:40

I-1

Sho Yamasaki, Osaka University, Japan
Regulation of immune responses via C-type lectin receptors

10:10

I-2

Florent Ginhoux, A*STAR, Singapore
Human Dendritic Cells: From Development to Functions

10:40

Coffee Break

11:00

I-3

Taishin Akiyama, RIKEN IMS, Japan
Dependence of homeostatic maturation of thymic antigen presenting cells on TNF receptor
family signaling

11:30I-4

Hai Qi, Tsinghua University, China
Bystander and antigen-specific T-B interactions

12:00
13:45

LunchI-5

Maria A. Curotto de Lafaille, New York University, USA
B cell memory of allergic responses

Short Talk 1 Harumichi Ishigame, RIKEN IMS,Japan
14:15
Developmental plasticity of effector CD8+ T cells generates functional heterogeneity ofmemory T cells
Session II: Functional genomic of lymphocytes: Next-generation technologies
Chair: N. Soranzo and T. Okada
14:30 II-1

Piero Carninci, RIKEN IMS, JapanAn emerging landscape of transcriptome complexity

15:00 II-2Nicole Soranzo, Wellcome Trust Sanger Institute, UK
Genetic and epigenetic determinants of transcriptional variation in immune cells

15:30

Coffee Break

15:50 II-3

Roser Vento, Wellcome Trust Sanger Institute, UK
Reconstructing the human first trimester fetal–maternal interface using single celltranscriptomics

16:20 II-4

Takaharu Okada, RIKEN IMS, Japan
Imaging of the epidermal nerve dynamics and activity in normal and pruritic dermatitis
conditions

Short Talk 2
16:50

Tsukasa Nabekura, University of Tsukuba, Japan
Tracking the fate of antigen-specific versus cytokine-activated natural killer cells after
cytomegalovirus infection

17:05

End of the day

Friday, June 8
Session III: Systems biology: Biochemistry, Immunology and environmental interactions
Chair: H. Ohno and V. O'Donnell
9:30

III-1 Hiroshi Ohno, RIKEN IMS, Japan
Small intestinal microbes act in concert to exacerbate autoimmune inflammation in thecentral nervous system

10:00

III-2 Masahira Hattori, RIKEN IMS, Japan
Novel genetic features in human gut microbiomes uncovered by long-read metagenomics

10:30

Coffee Break

10:50

III-3 Mariko Okada, Osaka University, Japan
Integrative analysis to reveal transcriptional regulation of NF-B

11:20

III-4 Valerie B. O’Donnell, Cardiff University, UK
Circulating blood cells generate immunoactive phospholipids that promote haemostasis,and regulate vascular inflammation.

11:50

Interacting with a publisher

12:20

Lunch

14:15

III-5 Toshihiko Ogura, Tohoku University, JapanThe M project --- Mechanical, Metabolism, Mitochondria and Muscles ---Short Talk 3 Yuki Sugiura, Keio University, Japan
14:45
Visualization of immune-brain metabolic competition between brain and lymph nodes bymass spectrometry imaging
Session IV: Cancer immunology / Immunotherapy
Chair: V. A. Boussiotis and H. Udono
15:00 IV -1 Tasuku Honjo, Kyoto University, JapanCancer immunotherapy by PD-1 blockade
15:30 IV -2 Vassiliki A. Boussiotis, Harvard Medical School, USA
Molecular and systemic mechanisms of PD-1 function
16:00

Coffee Break

16:20 IV -3

Heiichiro Udono, Okayama University, Japan
Anti-diabetes drug, Metformin, drives metabolic reprogramming of tumor microenvironment,
leading to inhibition of tumor growth

16:50 IV -4 Stefano Casola, IFOM, Italy
Targeting B cell antigen receptor function in mature B cell neoplasms: opportunities,
challenges and warnings
Short Talk 4 Kyoko Masuda, Kyoto University, Japan
17:20
Regeneration of tumor antigen specific CTLs using the iPSC technology
Closing Remarks:
17:35
Tadashi Yamamoto, Director, RIKEN IMS
18:00

Social gathering