蛍光標識グリコサミノグリカン使用論文
培養細胞への結合／細胞内取り込み
1) Urakawa H., Therapeutic potential of hyaluronan oligosaccharides for bonemetastasis of breast cancer. J Orthop Res, 2012, 30(4):662-72.
2) An Approach to Transgene Expression in Liver Endothelial Cells Using a
Liposome-Based Gene Vector Coated with Hyaluronic Acid. J Pharm Sci, 2013,102, 3119–3127.
3) Miyazaki T., Chondroitin Sulfate-E Binds to Both Osteoactivin and Integrin
aVb3 and Inhibits Osteoclast Differentiation. J Cell Biochem, 2015, 116:22472257.
4) Yamada Y., Hyaluronic acid controls the uptake pathway and intracellulartrafficking of an octaarginine-modified gene vector in CD44 positive- and CD44
negative-cells. Biomaterials, 2015, 52:189-98.
5) Laner-Plamberger S., Heparin Differentially Impacts Gene Expression ofStromal Cells from Various Tissues. Sci Rep, 2019, 9(1):7258.
6) Fell CW., FIBCD1 is an endocytic GAG receptor associated with a novel
neurodevelopmental disorder, EMBO Mol Med, 2022, 14(9) :e15829.
7) Mitani S., Generation of functional liver sinusoidal endothelial-like cells fromhuman bone marrow-derived mesenchymal stem cells. Regen Ther, 2023, 24:274281.
皮膚浸透性1)

Hashimoto N., The Effect of Iontophoresis with and without Electroporation on
the Penetration of High Molecular Compounds into the Stratum Corneum.
Chem Pharm Bull (Tokyo), 2022, 70(6):454-457.

2)Inoue S., Non-invasive Intradermal Delivery of Hyaluronic Acid via
Iontophoresis. Biol Pharm Bull, 2023, 46(11):1635-1638.

ヒアルロン酸分解活性測定
1)

Yoshida H., KIAA1199, a deafness gene of unknown function, is a new
hyaluronan binding protein involved in hyaluronan depolymerization. Proc Natl
Acad Sci U S A, 2013, 110(14):5612-7.

2)

Yoshida H., Murine homologue of the human KIAA1199 is implicated inhyaluronan binding and depolymerization. FEBS Open Bio, 2013, 3:352-6.

3)

Nagaoka A., Regulation of Hyaluronan (HA) Metabolism Mediated by HYBID

(Hyaluronan-binding Protein Involved in HA Depolymerization, KIAA1199) andHA Synthases in Growth Factor-stimulated Fibroblasts. J Biol Chem, 2015,
290(52):30910-23.
4)

Yamamoto H., A mammalian homolog of the zebrafish transmembrane protein
2 (TMEM2) is the long-sought-after cell-surface hyaluronidase. J Biol Chem,2017 , 292(18):7304-7313.

5)

Shiozawa J., Implication of HYBID (Hyaluronan-Binding Protein Involved inHyaluronan Depolymerization) in Hyaluronan Degradation by SynovialFibroblasts in Patients with Knee Osteoarthritis. Am J Pathol, 2020,
190(5):1046-1058.

6)

Tobisawa Y., The cell surface hyaluronidase TMEM2 is essential for systemic
hyaluronan catabolism and turnover. J Biol Chem, 2021, 297(5):101281.

7)

Shiozawa J., Expression and regulation of recently discovered hyaluronidases,
HYBID and TMEM2, in chondrocytes from knee osteoarthritic cartilage. Sci Rep,2022, 12(1):17242.

蛍光相関分光法（Fluorescence Correlation Spectroscopy）
1)

Miyazaki T., Oversulfated chondroitin sulfate-E binds to BMP-4 and enhancesosteoblast differentiation. J Cell Physiol, 2008, 217(3):769-77.

2)

Sahoo H., Influence of glycosaminoglycans on lipid dynamics in supported
phospholipid bilayers. Soft Matter, 2013, 9, 3859.

生体材料など1)

Naka Y., Wholly vascularized millimeter-sized engineered tissues by cell-sized
microscaffolds Mater Today Bio, 2020, 6:100054.

2)

Wille I., Development of Neuronal Guidance Fibers for Stimulating Electrodes:
Basic Construction and Delivery of a Growth Factor. Front Bioeng Biotechnol,
2022, 10:776890.