Information for Authors
The Journal of Toxicologic Pathology (JTP) is an official periodical journal of theJapanese Society of Toxicologic Pathology (JSTP), published 1 volume each year being
composed of 4 numbers. This is an international journal published in English andwelcoming papers from all over the world. JTP is a globally open-access journal, andall papers on the journal are capable of free downloading by the aids of the
Journal@rchive<http://www.journalarchive.jst.go.jp/japanese/jnltop_ja.php?cdjournal=tox1988> forvolumes 1 (year 1988) to 10 (year 1997) and the J-STAGE<http://www.jstage.jst.go.jp/browse/tox/-char/en> for volume 11 (year 1998) or later.
JTP has been selected for coverage in Thomson Reuters products and services, being
indexed and abstracted in Science Citation Index Expanded (also known as SciSearch®),Journal Citation Reports/Science Edition, Biological Abstracts and BIOSIS Previews,
beginning with volume 21, number 1 (year 2008). Papers on JTP are capable of beingreferred by a variety of international search engines including Google, Scopus,
ChemPort, CrossRef, Directory of Open Access Journals, NDL-OPAC (National Diet
Library of Japan) and SwetWise Online Contents, as well as Medical Online and
EBSCO (commercial services with charge).
Scope of article
JTP is a scientific journal that publishes original studies in the field of toxicologicalpathology and in a wide variety of other related fields. The main scope of the journal islisted below.
 Administrative Opinions of Policymakers and Regulatory Agencies
 Adverse Events
 Carcinogenesis
 Data of A Predominantly Negative Nature Drug-Induced Hematologic Toxicity
 Embryological Pathology
 High Throughput Pathology
 Historical Data of Experimental Animals
 Immunohistochemical Analysis
 Molecular Pathology
 Nomenclature of Lesions
 Non-mammal Toxicity Study Result or Lesion Induced by Chemicals of Which Names Hidden on Account of
the Authors Technology and Methodology Related to Toxicological Pathology
 Tumor Pathology; Neoplasia and Hyperplasia
 Ultrastructural Analysis
 Use of Animal Models

Submitted papers will be considered for publication on the condition that they arecontributed solely to JTP, have not been already published or are not underconsideration for publication elsewhere.
All articles published in JTP represent the opinion of the authors and should not be
construed to reflect the opinion of the society.
Types of article
Types of article: JTP publishes original articles, case reports, short communications,
technical reports and review articles.
1. Original articles: An article that contains new findings obtained from innovative
research.
2. Case reports: An article that contains new histopathological findings of
spontaneous and chemical-induced lesions in experimental animals.
3. Short communications: An article that contains preliminary or limited research
results supported by less data than the original article.
4. Technical reports: An article that contains data concerning technology or
methodology related to the toxicological pathology. The journal will also
publish historical data concerning histopathology of experimental animals as avaluable reference for pathological evaluation for toxicity assessment. Reports
of a predominantly negative nature are also suitable for publication as a technicalreport.
5. Review articles: Principally published upon invitation, but the society and theeditors do not hesitate to accept non-invited review articles, if they deserve.
In addition, Editor-in-Chief will set additional types of articles including Letter,
Forum and Report at the time of the publication of the journal when necessary.
Manuscript length: The standard length of article in printed pages is prescribed toevery type of the article. The standard length is 8 printed pages for the original article
and the technical report, 4 printed pages for the case report and the short communication,and 10 printed pages for the non-invited review article. There is no restriction for thenumber of pages in the case of the invited review article. Authors can write theirarticles with the lengths beyond these standards with extra expense (see Page charges).
Preparation of Manuscript
General format: Manuscripts should be prepared in English. Recommended digitalformats of documents, tables and illustrations for final publication-ready materials
requested to submit after the acceptance are described later in the Editorial Process
section. Those who cannot produce files of such formats are suggested to contact with
the Editorial Office by e-mail before preparing manuscripts. With the exceptions oftables and illustrations, authors should comply with the following general format.
1. Page setting as conventional A4 (approximately 21 x 30 cm) or US letter (8.5 x 11
inches) with ample margins.

2. Double-spacing.
3. Popular serif or sans-serif fonts such as Times and Arial and, for Greek characters,
Symbol fonts with 10 points.
4. Setting the title page as page 1 and paging in the lower right-hand corner endingat the end of the figure legends pages.
5. Arranging the order as follows.
a. Title page(s).
b. Abstract and then key words page(s) (after page-breaking).
c. Text and then acknowledgment pages (after page-breaking).
d. References pages (after page-breaking).
e. Figure legends page (s) (after page-breaking).
f. Tables.
g. Illustrations.
Authors are strongly recommended to refer papers already published in JTP tounderstand formatting rules including those not specified above or below.
Those who are not native English users should have appropriate language editing of
the manuscripts by native English speakers prior to the submission.
Nomenclature and unit: Every chemical used should be identified by a generic name,and at its first appearance the name and place (city and country, including Japan) of its
manufacturer should be presented. Abbreviations should be defined withinparentheses when first used in the text. Units are in general accordance with theInternational System of Units (SI units).
Ethical considerations: Submission of manuscripts reporting experimental research on
human materials or animals implies that authors have obtained approval for theirresearch from the appropriate ethics committee or other appropriate in-house, official or
governmental bodies regulating animal or human research. Such approval must ensurethat the experiments are planned and conducted strictly in accordance with all domestic
and international declarations, treaties, laws, regulations, guidelines, rules and so on.
Authors should also make their best consideration on animal welfare and good practiceof animal handling contributing to the replacement, refinement and reduction of animal
testing (3Rs). These ethical considerations including animal welfare and good practiceof animal handling should be clearly stated in the manuscript, usually in the Materials
and Methods section.
Conflict of interest disclosure: Potential conflicts of interest must be reported at thetime the manuscript is submitted. Research funding or other support from outside theauthors' stated affiliations must be clearly disclosed within the manuscript. The
corresponding author is responsible to ensure that the conflicts of interest disclosures
reported in the manuscript are accurate and consistent with the information provided by
all authors.

Copyright considerations: Any materials published elsewhere beforehand are notallowed to be included in any parts of the manuscripts, unless written consents are
obtained beforehand from their copyright owners. Those who wish to include suchmaterials in their manuscripts should then contact with Editor-in-Chief (through the
Editorial Office by e-mail), present him/her the documents describing the copyrightowners’ approval and obtain his/her agreement to refer the materials as well as guidance
for the way of their referring, prior to the submission of the manuscripts.
Title page: The title page should contain (1) a concise title; (2) full names of all
authors with the official names and full addresses, including zip codes and countries, of
their institutions; (3) a short running head (60 characters or less, including spaces); and(4) name, address, phone and facsimile numbers and e-mail address of thecorresponding author. In the title page, the declaration should also be made for any
financial support or relationships that may pose conflict of interest, if applicable.
Abstract: An abstract should be prepared to state the study's purpose, procedures,main findings, and conclusion. Abbreviations should be avoided. Abstracts should
be as concise as possible and not exceed 250 words for all types of articles. Abstracts ofcase reports and short communications, however, can be shorter, such as within 150
words.
Key words: A maximum of 6 key words should be provided for the subject indexing(following Medical Subject Headings of Index Medicus).
Text: In original articles, a text usually contains Introduction, Materials and Methods,
Results and Discussion sections as this order. Subheadings can be used in the
Materials and Methods, and Results sections. Case reports, short communications andtechnical reports should not adopt such sectioning. The text format of review articles
can be flexible to depend upon the nature of the article.
Acknowledgment: Personal acknowledgments should precede those for financial
supports. All sources of grants and other funding should be acknowledged in a
concrete manner (including numbers, if applicable).
References: References should be numbered in the order of citation in the text using
superscripts. The style to list references is exemplified as follows.
[Journal] Mahler JF, Davis BJ, Morham SG, and Langerbach R. Spontaneous
lesions in aging FVB/N mice. Toxicol Pathol. 24: 717-719. 1996.
[Book] Bannasch P and Gosner W. Pathology of Neoplasia and Preneoplasia in
Rodents. EULEP Color Atlas. Shattauer, New York. 1994.
[Part of book] Williams WJ. Secondary thrombocytosis. In: Williams Hematology,

5th ed. E Beutler, MA Lichtman, BB Coller, and TJ Kippa (eds). McGraw Hill,
New York. 1361-1363. 1995.
[Periodical] IARC. Post-menopousal Oestrogen Therapy. IARC Monographs on
the Evaluation of Carcinogenic Risks to Humans, Vol. 72. Lyon. 399-530. 1995.
[Electronic documents on government, university program or department website<Transient documents, such as those on newspaper websites, and documents withlow reliability, such as those on Wikipedia, should be avoided.>] Chou L,
McClintoch R, and Moretti F. Technology and education: New wine in bottles:
Choosing pasts and imagining educational futures. 2000, from Columbia University,
Institute for Learning Technologies website:
http://www.ilt.columbia.edu/publications/papers/newwine.html
Figure legends: Legends for illustrations should be with figure numbers in Arabic
numerals (such as Fig. 1) and brief titles. The title and footnotes should contain all
information necessary to understand and interpret the figure without reference to thetext. For photomicrographs, authors should note the staining method and indicate themagnification at the end of each legend, or include an appropriately sized bar in thephotograph with giving its equivalent size in the legend.
Tables: Tables should be prepared preferably each on separate page, with table
numbers in Arabic numerals (such as Table 1) and brief titles. The title and footnotes
should contain all information necessary to understand and interpret the table without
reference to the text. It should be avoided that similar data is presented both in figures
and tables in order to strengthen such data.
Illustrations: JTP is a full-color journal, and authors are thus recommended to preparecolor illustrations, especially photo(micro)graphs indicating pathological findings.
Illustrations (drawings, photo[micro]graphs, electron micrographs and etc) should be ofhigh quality and preferably prepared each on a separate page. The sizes to be printed
out as hardcopies should be estimated between 8.5 (single column) and 17.5 cm (double
column) in the horizontal width. Computer-generated images with high quality andsufficient contrast are acceptable.
Submission of Manuscript
Online Submission: All manuscripts should be submitted online at the URL of<http://mc.manuscriptcentral.com/jstp >. Upon submission, authors are requested toobey the step-by-step instructions described at the site. If authors encounter
difficulties that cannot be figured out during the submission, please feel free to contact
with the Editorial Office by e-mail.
Submitting manuscript files: Document files are preferred saved as a Microsoft Word
format. Tables are recommended saved as a Microsoft Word or Microsoft Excel

format. Digital files for images should be saved as an EPS, JPEG or TIFF format withthe minimal image size of 300 dpi in a grayscale or full color RGB mode (more than 8bits). Files saved as a Microsoft PowerPoint format may be acceptable, but each slide
should be labeled, and the “comments” cannot be included. If authors cannot savetheir materials as these formats, please contact with the Editorial Office by e-mail.
For those who are incapable of submitting manuscript online: Whereas thesubmission of manuscripts to JTP is to be performed online in principle, those who areincapable of doing so by some inevitable reasons may be allowed to submit theirmanuscripts via a postal mail. In this case, please contact with the Editorial Office
beforehand by e-mail.
Copyright transfer: A completed Copyright Transfer Agreement form should besigned by the corresponding author and send to the editorial office immediately after the
online submission of the manuscript to the JTP, either by using e-mail<jtp@ipec-pub.co.jp> or facsimile <+81-3-5978-4068>. It should be emphasized thatthe review process does not start, until the signed Copyright Transfer Agreement form
with sufficient information is received by the editorial office. The form can be
downloaded from the website of the JSTP
<http://www.japantoxpath.org/en/publication/jtp/submission/>.
After the publication, the copyright of papers and any other materials published in
JTP belong to JSTP and are protected as appropriate. It should be emphasized that
papers published in JTP are open-access articles distributed under the terms of theCreative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License<http://creativecommons.org/licenses/by-nc-nd/3.0/>. Nevertheless, those who wish
to get their photocopies are requested to obtain permission from the following
organization to which licensing of copyright clearance is delegated by the copyrightowner.
[All users except those in USA] Japan Academic Association for Copyright Clearance,
Inc. (JAACC); 9-6-41 Akasaka, Minato, Tokyo 107-0052, Japan; phone,+81-3-3475-5618; facsimile, +81-3-3475-5619; e-mail, <info@jaacc.jp>.
[Users in USA] Copyright Clearance Center, Inc.; 222 Rosewood Drive, Danvers,
MA 01923, USA; phone, +1-978-750-8400; facsimile, +1-978-646-8600.
Editorial Process
Reviewing: All manuscripts submitted will be critically reviewed by the members of
the Editorial Board or by specialists of the same field of study.
Proofreading: Accepted manuscripts will be sent back to the corresponding author
after English editing and checking of consistency by the Editorial Office for
proofreading. It is the authors’ responsibility to correct the alterations made by editors.

Page charges: The corresponding author will be invoiced to indicate the page charge
from the JSTP secretariat after publication. One text-only printed page contains
approximately 900 words, which roughly corresponds to 3 text pages of the Microsoft
Word with the standard setting (A4, double space and 11-12 words x 25-26 lines/page;
containing approximately 300 words). Tables and figures can be estimated by their
final sizes. The page charge is based on the number of printed pages. A standard
charge rate is applied for the pages of the articles within the standard length of theirarticle type, while an extra charge rate is applied for the pages beyond the standard
length. As aforementioned, JTP is a full-color journal, and thus there will be no extra
charges for the color printing. For the details of page charges, see the attached sheet.
Ordering reprints: An ordering form for reprints will be sent to authors with the proof.
Reprints of each paper are supplied by authors’ expense in multiples of 50.
MiscellaneousMaterial archive policy: Authors who wish to return any submitted materials (either
hardcopies or digital files) regarding their accepted manuscript should contact with the
Editorial Office by e-mail within 1 month of the acceptance. Otherwise, the society or
the editors will dispose such materials.
Correspondence: All correspondences should be addressed to the Editorial Office of
the Journal of Toxicologic Pathology, c/o Publication Center, IPEC, Inc., e-mail<jtp@ipec-pub.co.jp>.
This revision is valid from November 1, 2011.

Attached Sheet
Page Charge for the Papers Published in the Journal of Toxicologic Pathology

Standard
pages
Original Article
Case Report
Short Communication
Technical Report
Review Article

8
4
4
8
10

Page charge
Within the standard
Exceeding the standard
number of pages
number of pages(yen/page)(yen/page)
6,000
12,000
6,000
12,000
6,000
12,000
6,000
12,000
6,000
12,000A page charge is applied, based on the number of printed pages. One text-only printed
page contains approximately 900 words, which roughly corresponds to 3 text pages ofthe Microsoft Word with the standard setting (A4, double space and 11-12 words x
25-26 lines/page; containing approximately 300 words). Tables and figures can be
estimated by their final sizes.
The standard charge rate is applied for pages of the articles within the number ofstandard length, which are differently set by the type of article, while an extra charge
rate is applied for the pages beyond the standard length. Articles exceeding thestandard number of pages will be charged twice the standard charge per extra page.
There will be no extra charges for the color printing.