Science First – Clinical study

Five years of esthetic excellencewith NobelReplace® CC andNobelProcera® in the anterior maxilla
Clinical relevanceLong-term bonestability

Healthy soft tissue

Stable marginal bone levels
from initial remodelingto 5-year follow-up.

Soft tissue health improved
significantly from surgery
to prosthetic delivery andremained stable throughout.

High patientsatisfaction
with functionand esthetics
Continuous improvement
in oral health-related
quality of life.

Immediately provisionalized tapered conical connection implants for single-tooth restorations in the maxillary esthetic zone:
a 5-year prospective single-cohort multicenter analysis. Baer RA, Nölken R, Colic S, Heydecke G, Mirzakhanian C, Behneke A,Behneke N, Gottesman E, Ottria L, Pozzi A, Fügl A, Zechner W. Clinical Oral Investigations. 2022;26(4):3593-604.

The results

Marginal bone level change (mm)− Stable marginal bone levels, with a mean remodelingof -0.80 ± 1.13 mm from insertion to 5 years.
620+0.05±0.08+0.07±0.03-0.92±1.24-4-6-8− Full or more than half of the papilla heightregenerated at 90.1% of the sites at 5 years.
− Minimal or no sulcus bleeding at 98.8% of sites andlow plaque accumulation at 93.8% of sites at 5 years.

4-2− High implant survival rate at 5 years of 97.8%.

Insertion to 6 months(n=89)

6 months to 1 year
(n=88)

1 year to 5 years(n=74)− High Pink Esthetic Score of >9.1 at 1 through 5-year
follow-up visits.
− High patient satisfaction with function and esthetics,
with the mean complaint rate (OHIP-14) of 0.84 on ascale of 0 to 14 at 5 years.

Study design
Prospective, singlecohort, multicenter

94 patients

Single-tooth
Anterior maxilla
Immediate
provisionalization

99 NobelReplaceCC

78 NobelProcera
single crowns+ 18 others

5-year follow-up

Sample clinical case from the study
Implant insertion

aFinal prosthetic delivery

1 yearbc

3 yearsd

5 years

eImages courtesy of Drs. Alexandra and Nicolaus Behneke, Germany

45-year-old female patient with no history of periodontitis received NobelReplace CC 3.5 x 13 mm in the firstpremolar site, FDI position 14 (a). Bone quality was hard (type 2), and the final insertion torque was 45 Ncm.
The implant was immediately provisionalized. Clinical images and radiographs acquired at final prosthetic
delivery, and 1-, 3- and 5-year follow-up (b-e) show healthy hard- and soft-tissue responses, accompanied bya visible improvement in esthetics.

Authors' conclusion“The high survival and success rates of immediately
provisionalized NobelReplace CC implants in theesthetic zone combined with the good peri-implanttissue health were reflected in continuous improvementin patient oral health-related quality of life.”

More to explore

Read on PubMed

FOR. Interface
precision in conicalconnection implants

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