Symposium
1SDa

June 24 (Mon) 9:00-11:30 (tentative)＜Session Language: Japanese＞

Several oral presentations will be chosen from the free papers
Intrinsic and extrinsic regulation of development
Organizars: Daichi Kawaguchi (The Univ. of Tokyo), Kyogo Kawaguchi (RIKEN)
Speakers: Daichi Kawaguchi (The Univ. of Tokyo), Kyogo Kawaguchi (RIKEN),
Mototsugu Eiraku (Kyoto Univ.), Shizue Ohsawa (Nagoya Univ.),
Jun Hatakeyama (Kumamoto Univ.)
Timing and order of cell fate decision are intrinsically programmed during development. Although thedevelopmental schedule is precisely determined, mechanisms governing the “timer” have remainedlargely unclear. This cell intrinsic timer gets feedback from extracellular environments to control organ
size and morphogenesis. In this symposium, we will discuss recent advances in our understanding of
intrinsic and extrinsic mechanisms regulating cell fate determination.
1SEa

June 24 (Mon) 9:00-11:30 (tentative)＜Session Language: Japanese＞

Oral presentations will NOT be chosen from the free papers
Thermal Biology: Temperature sensing and cellular function
Organizars: Naoko Imamoto (RIKEN), Yoshie Harada (Osaka Univ.)
Speakers: Masato Umeda (Kyoto Univ.), Kohki Okabe (The Univ. of Tokyo), Naoko Imamoto (RIKEN),
Reiko Sakaguchi (Kyoto Univ.), Teruaki Taiji (Tokyo Univ. of Agriculture),
Motoaki Seki (RIKEN ), Atsushi Kuhara (Konan Univ.)
Temperature affects various physiological functions and is one of the most important factors inhomeostasis. Temperature sensing involves proteins, lipids and RNAs, and significance of different
temperature sensing system is studied in various species including plants and animals. We discuss andintroduce various temperature sensing systems and temperature imaging technique.
1SDp

June 24 (Mon) 16:45-19:15 (tentative)＜Session Language: Japanese＞

Oral presentations will NOT be chosen from the free papers
Frontier Research on Chemical Communications
Organizars: Kazuya Kikuchi (Osaka Univ.), Hideaki Kakeya (Kyoto Univ.)
Speakers: Hideaki Kakeya (Kyoto Univ.), Yoko Yashiroda (RIKEN ), Tatsushi Igaki (Kyoto Univ.),
Ikuo Tsunoda (Kindai Univ.), Hidekazu Hiroaki (Nagoya Univ.), Kazuya Kikuchi (Osaka Univ),
Essential roles of natural products as chemical communication molecules among microbes, animals,plants, et cetera have not been fully elucidated. Integrated understanding of various kinds of chemicalcommunications could therefore accelerate functional regulation by utilizing chemical communication
molecules. In this symposium, current topics on chemical communication research will be presented anddiscussed.

1SEp

June 24 (Mon) 16:45-19:15 (tentative)＜Session Language: Japanese＞

Oral presentations will NOT be chosen from the free papers
Singurality biology
Organizars: Takeharu Nagai (Osaka Univ.), Kazuki Horikawa (Tokushima Univ.)Speakers: Tomonobu M Watanabe (RIKEN), Katsuyuki Shiroguchi (RIKEN), Shuichi Onami (RIKEN),
Atsuyoshi Nakamura (Hokkaido Univ.), Hiroko Bannai (JST PRESTO/ RIKEN),
Hitoshi Hashimoto (Osaka Univ.), Taku Okazaki (Tokushima Univ.)
Physiological and pathological cell population often display the abrupt change in their dynamics. Such a
critical transition, we call singularity, is believed to be triggered by core reactions involving a small
number of cells. In this symposium, weʼll discuss how the rare event controls the system dynamics byshowing our strategy, theory and biological examples of the singularity-associated phenomena.
2SBa

June 25 (Tue) 8:45-11:15＜Session Language: Japanese＞

Oral presentations will NOT be chosen from the free papers
New trends of protein science under multimolecular crowding biosystems
Organizars: Itaru Hamachi (Kyoto University), Akio Ojida (Kyushu University)
Speakers: Itaru Hamachi (Kyoto Univ.), Akio Ojida (kyushu Univ.), Toru Komatsu (The Univ. of Tokyo),
Shinya Tsukiji (Nagoya Institute of Technology), Satoko Akashi (Yokohama City Univ.),
Susumu Uchiyama (Osaka Univ.)
Protein molecules act a variety of functions under multimolecular crowding biosystems like live cells,
tissues and whole bodies. We would like to discuss valuable molecular tools and methods for analyzing
and controlling proteins localization, structure and functions in such complex natural habitats.

2SDa

June 25 (Tue) 8:45-11:15＜Session Language: Japanese＞

Several oral presentations will be chosen from the free papers
The homeostatic control of chromosomes
Organizars: Toru Hirota (Cancer Inst. JFCR), Katsuhiko Shirahige (The University of Tokyo)
Speakers: Tatsuo Fukagawa (Osaka Univ.), Atsushi Mochizuki (kyoto Univ.), Tetsuji Kakutani (NIG),
Arisa Oda (The Univ. of Tokyo), Tomomi Tsubouchi (NIBB), Takehiko Itoh (Tokyo Inst. Tech.)
Chromosomes are fundamental to all life processes, by providing macromolecular frameworks for multiple
genome functions. The MEXT Priority Research Area “Chromosomal Orchestration System” has been
aimed to study the integrated functions on chromosomes, which lead to hypothesize that chromosomes
are highly plastic, and its structural regulation has overwhelming impacts on cellular/organismal
phenotypes. This symposium will focus on the homeostatic control of chromosomes that confers
plasticity, and discuss how might they contribute to cellular evolution and pathology.

2SEaJune 25 (Tue) 8:45-11:15＜Session Language: Japanese＞

Several oral presentations will be chosen from the free papers
Regulation of transcription in the context of chromatin and nuclear structdures
Organizars: Noriko Saitoh (The Cancer Instit. of JFCR), Hidetoshi Kono (QST)
Speakers: Hidetoshi Kono (QST), Yuma Ito (Tokyo Inst. of Tech.),Takahiro Sakaue (Aoyama Gakuin Univ.), Saori Takahashi (RIKEN ),Tomoya Kujirai (The Univ. of Tokyo), Tetsuya Handa (Tokyo Inst. of Tech.),Genes are regulated at various levels of chromatin. At molecular level, factors which change posttranslational modifications of chromatin have been identified. At cellular level, domain organization ofchromatin in the nucleus have been recognized to be deeply relevant to gene activity. In this symposium,
we focus on the regulation of transcription through multiple layers of chromatin and nuclear structures.

2SDp

June 25 (Tue) 16:30-19:00＜Session Language: Japanese＞

Several oral presentations will be chosen from the free papers
New frontier of ubiquitin research – from phase separation to small-molecule degraders
Organizar: Yasushi Saeki (Tokyo Metropo. Inst. of Med. Sci.)
Speakers: Sayaka Yasuda (Tokyo Metropol. Inst. Med. Sci.), Daichi Morimoto (Kyoto Univ.),
Yusuke Sato (The Univ. of Tokyo), Shoshiro Hirayama (The Univ. of Tokyo),
Fuseya Yasuhiro (Kyoto Univ.), Norihito Shibata (NIHS), Takumi Ito (Tokyo Medical Univ.)
Ubiquitylation is an important post-translational modification that regulates almost all cellular functions,but there are still many mysteries on ubiquitin. In this symposium, we will introduce novel ubiquitin
studies such as phase separation of ubiquitin, recognition and spatio-temporal regulation of ubiquitylated
proteins, and targeted protein degradation methods by small compounds.

2SEp

June 25 (Tue) 16:30-19:00＜Session Language: Japanese＞

Oral presentations will NOT be chosen from the free papers
Challenges for investigating cellular diversity in the living system
Organizars: Etsuo A. Susaki (The Univ. of Tokyo), Ryohei Katayama (JFCR)
Speakers: Atushi Muroi (Kanagawa Cancer Ctr. Res. Inst.), Hiroo Ueno (Kansai Medical Univ. ),Ryohei Katayama (JFCR), Kazuhide Watanabe (RIKEN ), Yuichiro Nakajima (Tohoku Univ.),
Etsuo A. Susaki (The Univ. of Tokyo)
The aim of this symposium is to introduce researches toward the analysis and regulation of cellular
diversity in the living system. We will particularly focus on the three viewpoints as 1) the analysis at themolecular level, 2) the analysis at the cell population level, 3) the analysis at the organ and the organism
level of cellular diversity in the normal and disease states.

3SBaJune 26 (Wed) 8:45-11:15＜Session Language: English＞

Several oral presentations will be chosen from the free papers
Resonance between cell biology and new imaging modalities
Organizar: Michiyuki Matsuda (Kyoto Univ. )Speakers: Yuri E. Korchev (Imperial Col. London), Hidekazu Tsutsui (JAIST ), Kenta Terai (Kyoto Univ. ),Satoshi Iwano (RIKEN ), Yuko Mimori-Kiyosue (RIKEN )Progress of cell biology depends strongly on the inventions in imaging. New modalities widen the scale ofimaging below Abbe limit and over the mouse size. We hope the audiences will envisage new discovery intheir research area by the resonance between cell biology and new imaging modality.

3SEa

June 26 (Wed) 8:45-11:15＜Session Language: English＞

Oral presentations will NOT be chosen from the free papers
Proteins Controlling Membranes: Morphogenesis, Interaction and Fusion
Organizars: Shuh-ichi Nishikawa (Niigata University), Tomoko Igawa (Chiba University)
Speakers: Tomoko Igawa (Chiba Univ. ), Hitoshi Nakatogawa (Tokyo Inst. of Tech.),Shuh-ichi Nishikawa (Niigata Univ.), Benjamin Podbilewicz (Technion-Israel Inst. Tech.),Shiro Suetsugu (Nara Inst. Sci. Tech.), Gavin James Wright (Wellcome Sanger Inst.)
Recent advances in our understanding of various biological processes including autophagy, cell fusion andfertilization, especially in mechanisms of membrane interactions, largely depend on identification andanalyses of proteins functioning as key players in these processes. In this symposium, speakers fromvarious research fields will present their recent findings on how proteins control membrane
morphogenesis, interaction or fusion steps from inside or outside of cells.

3SFa

June 26 (Wed) 8:45-11:15＜Session Language: English＞

Oral presentations will NOT be chosen from the free Papers
Precisely controlled reaction mechanism of membrane proteins revealed by the forefronts of experimenta
and theoretical sciences
Organizars: Michi Suga (Okayama University), Jina-Ren Shen (Okayama University)
Speakers: Minoru Kubo (Univ. of Hyogo), Shigehiko Hayashi (Kyoto Univ.),
Radostin Danev (The Univ. of Tokyo), Michi Suga (Okayama Univ.),
Hiroshi Ishikita (The Univ. of Tokyo), Wenda Wang (Institute of Botany, CAS)
Membrane proteins play essential roles in the biological system such as photosynthesis, respiration andmembrane transport. In this symposium, the world-leading researchers from experimental andtheoretical sciences will have stimulating and fruitful presentations about how the forefronts have brought
new insights into the precisely controlled reaction mechanisms of membrane proteins.