Publication list of Kenji Okuda
1. OKuda K, Wada Y, Shimada M. Recent Developments in Preclinical DNA
Vaccination Vaccines 2014: 2(1), 89-106.
2. Shimada M, Abe S, Takahashi T, Shiozaki K, Okuda M, Mizukami H, Klinman
DM, Ozawa K, Okuda K. Prophylaxis and treatment of Alzheimer's disease
by delivery of an adeno-associated virus encoding a monoclonal antibody
targeting the amyloid Beta protein. PLoS One.: 2013;8(3):e57606. Epub
2013.
3. Akatsu H, Iwabuchi N, Xiao JZ, Matsuyama Z, Kurihara R, Okuda K,
Yamamoto T, Maruyama M. Clinical effects of probiotic Bifidobacterium
longum BB536 on immune function and intestinal microbiota in elderly
patients receiving enteral tube feeding. JPEN J Parenter Enteral Nutr.: 2013
Sep;37(5):631-40. Epub 2012.
4. Shoji M, Yoshizaki S, Mizuguchi H, Okuda K, Shimada M. Immunogenic
comparison of chimeric adenovirus 5/35 vector carrying optimized humanimmunodeficiency virus clade C genes and various promoters. PLoS One.:2012;7(1) e30302. Epub 2012.
5. Shimada, M., Yoshizaki, S., Jounai, N., Kondo, A., Ichino, M., Ryo, A., Okuda
K. DNA vaccine expressing HIV-1 gp120/immunoglobulin fusion protein
enhances cellular immunity. Vaccine, 2010;28(31):4920-7.
6. Yashima S, Yoshizaki S, Shinoda K, Yoshida A, Kondo A, Mizuguchi H, Ryo
A, Okuda K, Shimada M.
Co-administration of viral vector-based vaccines
suppresses
antigen-specificeffector
CD8Tcells.
Vaccine.
2010;28(18):3257-64.
7. Wang HB, Kondo A, Yoshida A, Yoshizaki S, Abe S, Bao LL, Mizuki N, Ichino
M, Klinman D, Okuda K, Shimada M. Partial protection against SIV challenge
by vaccination of adenovirus and MVA vectors in rhesus monkeys. Gene
Ther. 2010 ;17(1):4-13.
8. Yashima S, Yoshizaki S, Shinoda K, Yoshida A, Kondo A, Mizuguchi
H, Ryo A, Okuda K, Shimada M. Co-administration of viral vector-based
vaccines suppresses antigen-specific effector CD8 T cells. Vaccine.
19;28(18):3257-64.

9. Wang HB, Kondo A, Yoshida A, Yoshizaki S, Abe S, Bao LL, Mizuki N, Ichino
M, Klinman D, Okuda K, Shimada M. Partial protection against SIV challenge
by vaccination of adenovirus and MVA vectors in rhesus monkeys. Gene
Ther. 2010 ;17(1):4-13.
10. Kobiyama K, Takeshita F, Ishii KJ, Koyama S, Aoshi T, Akira S,
1

Sakaue-Sawano A, Miyawaki A, Yamanaka Y, Hirano H, Suzuki K, Okuda K. A
signaling polypeptide derived from an innate immune adaptor molecule canbe harnessed as a new class of vaccine adjuvant.
J Immunol.
2009 ;182(3):1593-1601.
11. Ura T, Yosida A. ,Xin K.Q., Yashima S., Abe S.,Mizuguchi H. and Okuda K.:
Designed envelope-specificCD8+ cytotoxic T lymphocytes andcross-reactive neutralizing antibodies against human immunodeficiency
virus type 1. J.Gene Med. 2009 11(2):139-149.
12. Shimada, M., Wang, H-B., Ino, A., Xu, X-P., Yoshida, A., Ura, T., Mizuguchi,
H .Klinman, D., Luo, J-L., Bai, H., Okuda, K. Effect of therapeutic
immunization using Ad5/35 and MVA vectors on SIV-infection of rhesus
monkeys undergoing anti-retroviral therapy. Gene Ther. 2009:16(2):218-228.
13. Takeshita F., Kobiyama K., Miyawaki A., Jounai N. and Okuda K: The
non-canonical role of Atg family members as suppressors of innate antiviral
immune signaling. Autophagy, 2008, 4, 1-4.
14. Ohba K., Yoshida S., Zahidunnabi Dewan M., Shimura H., Sakamaki N.,
Takeshita F., Yamamoto N. and Okuda K: Mutant influenza A virus
nucleoprotein is preferentially localized in the cytoplasm and its
immunization in mice shows higher immunogenicity and cross-reactivity.
Vaccine, 2007,25: 3186-3197.
15. Jounai N., Takeshita F., Kobiyama K., Sawano A., Miyawaki A., Xin KQ., Ishii
J.K., Kawai T., Akira S., Suzuki K. and Okuda K: The Age5-Age12 Conjugate
Associates
with
InnateAnti
viral
ImmuneResponses.
Proc.Nat.Acad.Sci.,2007, 104(35), 14050-1455.
16. Someya k., Xin K.Q., Ami Y., Izumi Y., Mizuguchi H., Ohta S., Yamamoto N.,
Honda M., Okuda K: Chimeric adenovirus type 5/35 vector encoding SIV gag
and HIV env genes affords protective immunity against the simian/humanimmunodeficiency virus in monkeys. Virology 2007, 367(11), 390-397.
17. Saha S., Takeshita F., Matsuda T., Jounai N., Kobiyama K., Matsumoto T.,
Sasaki S., Yoshida A., Xin KQ., Klinman DM., Uematsu S., Ishii KJ., Akira S.,
and Okuda K. Blocking of the TLR5 activation domain hampers protective
potential of DNA vaccine targeting flagellin. J. Immunol., 2007,179(2),1147-1154.
18. Xin, K.Q., Sekimoto, Y., Takahashi, T., Mizuguchi, H., Ichino, M., Yoshida, A.
& Okuda, K. Chimeric adenovirus 5/35 vector containing the clade C HIV gag
gene induces a cross-reactive immune response against HIV. Vaccine
2007,25(19),3809-15.
219. Kojima, Y., Jounai, N., Takeshita, F., Nakazawa, M., Okuda, K., Watabe, S.,
Xin, K.Q. The degree of apoptosis as an immunostimulant for a DNA vaccine
against HIV-1 infection. Vaccine 2007, 25(3), 438-445.
20. Watanabe K., Sonoda T., Miyagi Y., Yamashita T., Okuda K., Kawamoto S. The
synaptic scaffolding protein Delphinline interacts with monocarboxylatetransporter 2. NeuroReport 2007,18, 489-493.
21. Someya K., Xin K.-Q., Nakasone T., Ami Y., Izumi Y., Mizuguchi H., Ohta S.,
Yamamoto N., Honda M. & Okuda K. (2006 ) Positive anti-viral immunity iselicited by priming macaques with human immunodeficiency virus(HIV) env
and simian immunodeficiency virus (SIV) gag plasmid DNAs and boostingwith recombinant chimeric adenovirus type 5 with type 35 (Ad5/35) fiber. J
Virol.80,2005-2013.
22. Urabe M., Nakakura T., Xin K.Q., Obara Y., Mizukami H., Kume A., Kotin R.M.
& Ozawa K. (2006) Scalable generation of high-titer recombinantadeno-associated virus type 5 in insect cells. J Virol, 80, 1874-85.
23. Takeshita F., Tanaka T., Matsuda T., Tozuka M., Kobiyama K., Saha S.,
Matsui K., Ishii K.J., Coban C., Akira S., Ishii N., Suzuki K., Klinman D.M.,
Okuda K. & Sasaki S. (2006) Toll-like receptor adaptor molecules enhanceDNA-raised adaptive immune responses against influenza and tumors
through activation of innate immunity. J Virol, 80, 6218-24.
24. Someya K., Ami Y., Nakasone T., Izumi Y., Matsuo K., Horibata S., Xin K.Q.,
Yamamoto H., Okuda K., Yamamoto N. & Honda M. (2006) Induction of
positive cellular and humoral immune responses by a prime-boost vaccine
encoded with simian immunodeficiency virus gag/pol. J Immunol, 176,
1784-95.
25. Shinoda K., Xin K.Q. & Okuda K. (2006) A modified HIV challenge assay inmice by using luciferase-expressing vaccinia virus. Vaccine, 24, 2751-4.
26. Saha S., Takeshita F., Sasaki S., Matsuda T., Tanaka T., Tozuka M., Takase
K., Matsumoto T., Okuda K., Ishii N., Yamaguchi K., Klinman D.M. & Xin K.Q.
(2006) Multivalent DNA vaccine protects mice against pulmonary infection
caused by Pseudomonas aeruginosa. Vaccine, 24, 6240-9.
27. Saha S., Yoshida S., Ohba K., Matsui K., Matsuda T., Takeshita F., Umeda K.,
Tamura Y., Okuda K., Klinman D., Xin K.-Q. & Okuda K. (2006) A fused geneof nucleoprotein (NP) and herpes simplex virus genes (VP22) induces highly
protective immunity against different subtypes of influenza virus. Virology,
354, 48-57.
28. Oomura K., Xin K.Q., Takakura M., Shinoda K., Jounai N. & Okuda K. (2006)
Oral administration of the adenovirus vector induces systemic immunity3

rather than intestinal mucosal immunity. Vaccine, 24, 1045-1046.
29. Matsuda R., Bostrom A.C., Fredriksson M., Fredriksson E.L., Bratt G.,
Hejdeman B., Sandstrom E., Okuda K. & Wahren B. (2006) Human
immunodeficiency virus-type 1 specific cellular immunity in chronic
infected patients on prolonged highly active antiretroviral treatment and on
structured treatment interruption. Microbiol Immunol, 50, 629-635..
30. Yokoo N., Saito T., Uesugi M., Kobayashi N., Xin K.-Q., Okuda K., Mizukami
H., Ozawa K. & Koshino T. (2005) Repair of articular cartilage defect byautologous transplantation of basic fibroblast growth factor
gene-transduced chondrocytes with adeno-associated virus vector.
Arthritis Rheum, 52, 164-70.
31. Yamashita T., Miyagi Y., Ono M., Ito H., Watanabe K., Sonoda T., Tsuzuki K.,
Ozawa S., Aoki I., Okuda K., Mishina M. & Kawamoto S. (2005) Identificationand characterization of a novel Delphilin variant with an alternative
N-terminus. Brain Res Mol Brain Res, 141, 83-94.
32. Xin K.-Q., Ohta S., Jounai N. & Okuda K. (2005) Comparison of
antigen-specific cellurar immune responses between individual PBMCs andsplenocytes. Vaccine, 23, 2954-5.
33. Xin K.-Q., Jounai N., Someya K., Honma K., Mizuguchi H., Hayakawa T.,
Hamajima K., Saha S., Takeshita F., Okuda K., Honda M., Klinman D.M. &Okuda K. (2005) Prime-boost vaccination with plasmid DNA and a chimericadenovirus type 5 vector with type 35 fiber induces persistent protective
immunity against HIV. Gen Ther, 12, 1769-77.
34. Tamura Y., Hamajima K., Matsui K., Yanoma S., Narita M., Tajima N., Xin
K.-Q., Klinman D. & Okuda K. (2005) The F(ab´)2 fragment of an Ab-specificmonoclonal antibody reduces Ab-deposits in the brain. Neurobiol Dis, 20,
541-9.
35. Takeshita F., Ishii K.J., Kobiyama K., Kojima Y., Coban C., Sasaki S., Ishii N.,
Klinman D. M., Okuda K., Akira S. & Suzuki K. (2005) TRAF4 acts as asilencer in TLR-mediated signaling through the association with TRAF6 andTRIF. Eur. J. Immunol., 35, 2477-785.
36. Takakura M., Okuda K., Matsuda T., Takeshita F., Takakura H., Ikezawa Z. &Xin K.Q. (2005) Combination of DNA vaccine and adenovirus vector by
cutaneous administration induced strong HIV-specific cellular immune
responses in mice. Vaccine, 23, 847-8.
37. Takakura M., Takeshita F., Aihara M., Xin K.Q., Ichino M., Okuda K. &Ikezawa Z. (2005) Hyperproduction of IFN-gamma by CpG
oligodeoxynucleotide-induced exacerbation of atopic dermatitis-like skin4lesion in some NC/Nga mice. J Invest Dermatol, 125, 1156-62.
38. Someya K., Cecilia D., Ami Y., Nakasone T., Matsuo K., Burda S., Yamamoto
H., Yoshino N., Kaizu M., Ando S., Okuda K., Zolla-Pazner S., Yamazaki S.,
Yamamoto N. & Honda M. (2005) Vaccination of rhesus macaques withrecombinant mycobacterium bovis calmette-guerin env V3 elicites
neutralizing antibody-mediated protection against simian-humanimmunodeficiency virus with a homologous but not a heterologous V3 motif.
J Virol., 79, 1452-62.
39. Shen Y., Ichino m., Nakazawa M., Ikejima T., Kojima Y., Okuda K. & Minami M.
(2005) Therapeutic effect of CpG-enriched plasmid administration on thetight-skin mouse model of scleroderma. J Autoimmune, 24, 183-90.
40. Ozaki T., Yauchi M., Xin K.-Q., Hirahara F. & Okuda K. (2005) Cross reactive
protection against influenza A virus by a topically applied DNA vaccine
encoding M gene with adjuvant. Viral Immunol, 18, 373-80.
41. Hiraide A., Yokoo N., Xin K.-Q., Okuda K., Mizukami H., Ozawa K. & Saito T.
(2005) Repair of articular cartilage defect by intra-articular administration ofbasic fibroblast growth factor gene using the adeno-associated virus vector.
Hum Gene Med., 16, 1413-21.
42. Tanaka S.I., Yamakawa T., Kimura M., Aoki I., Kamei J., Okuda K. & Mobbs C.
(2004) Daily nasal inoculation with the insulin gene ameliorates diabetes inmice. Diabetes Res Clin Pract., 63, 1-9.
43. Takenouchi H., Kiyokawa N., Taguchi T., Matsui J., Katagiri Y.U., Okita H.,
Okuda K. & Fujimoto J. (2004) Shiga toxin binding to globotriaosyl ceramide
induces intracellular signals that mediate cytoskeleton remodeling inhuman renal carcinoma-derived cells. J Cell Sci, 117, 3911-22.
44. Someya K., Xin K.-Q., Matsuo K., Okuda K., Yamamoto N. & Honda M. (2004)
A consecutive prime-boost vaccination of mice with simian
immunodeficiency virus (SIV) gag/pol DNA and recombinant vaccinia virus
DIs elicits effective anti-SIV immunity. J Virol, 78, 9842-53.
45. Sirivichayakul S., Tirawatnapong T., Ruxrungtham K., Oelrichs R., Lorenzen
S.L., Xin K.-Q., Okuda K. & Phanuphak P. (2004) Construction andimmunogenicity study of a 297-bp humanized HIV V3 DNA of an
approximated last common ancestor in mice. Asian Pac J Allergy Immunol.,22, 49-60.
46. Shinoda K., Xin K.-Q., Jounai N., Kojima Y., Tamura Y., Okada E., Kawamoto
S., Okuda K., Klinman D. & Okuda K. (2004) Polygene DNA vaccine induces
a high level of protective effect against HIV-vaccinia virus challenge in mice.
Vaccine, 22, 3676-90.
547. Sasaki S., Takeshita F., Oikawa T., Kojima Y., Xin K.-Q., Okuda K. & Ishii N.
(2004) Improvement of DNA vaccine immunogenicity by a dual antigen
expression system. Biochem Biophys Res Commun, 315, 38-43.
48. Hinkula J., Rollman E., Lundholm P., Benthin R.M., Okuda K. & Wahren B.
(2004) Genetic immunization with multiple HIV-1 genes provides protection
against HIV-1/MuLV pseudovirus challenge in vivo. Cells Tissues Organs,177.
49. Devito C., Zuber B., Schroder U., Benthin R., Okuda K., Broliden K., Wahren
B. & Hinkula J. (2004) Intranasal HIV-1-gp160-DNA/gp41 peptide prime-boost
immunization regimen in mice results in long-term HIV-1 neutralizing
humoral mucosal and systemic immunity. J Immunol, 173, 7078-89.
50. Yamakawa T., Tanaka S., Kamei J., Kadonosono K. & Okuda K. (2003)
Pitavastatin inhibits vascular smooth muscle cell proliferation byinactivating extracellular signal-regulated kinases 1/2. J Atheroscler
Thromb, 10, 37-42.
51. Yamakawa T., Tanaka S., Kamei J., Kadonosono K. & Okuda K. (2003)
Phosphatidylinositol 3-kinase in angiotensin II-induced hypertrophy ofvascular smooth muscle cells. Eur J Pharmacol, 478, 39-46.
52. Xin K.-Q., Ooki T., Jounai N., Mizukami H., Hamajima K., Kojima y., Ohba K.,
Toda Y., Hirai S., Klinman D.M., Ozawa K. & Okuda K. (2003) A DNA vaccine
containing inverted terminal repeats from adeno-associated virus increases
immunity to HIV. J Gene Med, 5, 438-45.
53. Xin K.-Q., Hoshino Y., Toda Y., Igimi S., Kojima Y., Jounai N., Ohba K.,
Kushiro A., Kiwaki M., Hamajima K., Klinman D. & Okuda K. (2003)
Immunogenicity and protective efficacy of orally administered recombinant
Lactococcus lactis expressing surface-bound HIV Env. Blood, 102, 223-8.
54. Taniya T., Mitobe J., Nakayama S., Qi M., Okuda K. & Watanabe H. (2003)
Determination of the InvE binding site required for expression of IpaB of the
Shigella sonnei virulence plasmid: Involvement of a ParB BoxA-likesequence. J Bacteriol, 185, 5158-65.
55. Sasaki S., Takeshita F., Xin K.-Q., Ishii N. & Okuda K. (2003) Adjuvant
formulations and delivery systems for DNA vaccines. Methods, 31, 243-54.
56. Kawamoto S., Sonoda T., Mochizuki C., Yamashita T., Watanabe K., Miyagi Y.
& Okuda K. (2003) Glutamate receptor ä2-mediated signal transduction
through Delphilin: analysis by Biacore and a yeast two-hybrid system. In:
Biacore Journal, Vol. 3, p. 12-4.
57. Jounai N., Okuda K., Kojima Y., Toda Y., Hamajima K., Ohba K., Klinman D.
& Xin K.-Q. (2003) Contribution of the rev gene to the immunogenicity of6

DNA vaccines targetting the envelope glycoprotein of HIV. J Gene Med, 5,609-17.
58. Hamajima K., Kojima Y., Matsui K., Toda Y., Jounai N., Ozaki T., Xin K.-Q.,
Strong P. & Okuda K. (2003) Chitin micro-particles (CMP) is a usefuladjuvant for inducing viral specific immunity when delivered intranasallywith an HIV-DNA vaccine. Viral Immunol, 16, 541-7.
59. Xin K.-Q., Kumamoto Y., Jounai N., Kojima Y., Hamajima K. & Okuda K.
(2002) Recombinant vaccinia virus (WR strain) may not be suitable for exvivo stimulation. Vaccine, 21, 5-6.
60. Xin K.-Q., Sasaki S., Kojima Y., Jounai N., Kumamoto Y., Hashimoto K.,
Shinoda K., Hamajima K. & Okuda K. (2002) Detection of progeny immune
responses after intravenous administration of DNA vaccine to pregnant
mice. Biol Proced Online, 3, 91-101.
61. Xin K.-Q., Ooki T., Mizukami H., Hamajima K., Okudera K., Hashimoto K.,
Kojima Y., Jounai N., Kumamoto Y., Sasaki S., Klinman D., Ozawa. K. &Okuda K. (2002) Oral administration of recombinant adeno-associated virus
elicits HIV-specific immune responses. Hum Gene Ther, 13, 1571-81.
62. Senuma A., Hagiwara E., Nagahama K., Okuda K., Nakamura M., FukumotoN., Shirai A., Tani K. & Ishigatsubo Y. (2002) Therapeutic effect of CpG
motifs on the development of chronic graft-versus-host disease in mice.
Cytokine, 20, 23-9.
63. Sasaki S., Takeshita F., Ishii N., Xin K.-Q. & Okuda K. (2002) How to amplify
DNA-raised immune responses. Current Trends in Immunology, 4, 115-26.
64. Sasaki S., Xin K.-Q., Okudela K., Okuda K. & Ishii N. (2002)
Immunomodulation by apoptosis-inducing caspases for an influenza DNA
vaccine delivered by gene gun. Gene Ther, 9, 828-31.
65. Murata H., Tajima N., Nagashima Y., Yao M., Baba M., Goto M., Kawamoto S.,
Yamamoto I., Okuda K. & Kanno H. (2002) Von Hippel-Lindau tumor
suppressor protein transforms human neuroblastoma cells into functional
neuron-like cells. Cancer Res, 62, 7004-11.
66. Miyagi Y., Yamashita T., Fukaya M., Sonoda T., Okuno T., Yamada K.,
Watanabe M., Nagashima Y., Aoki I., Okuda K., Mishina M. & Kawamoto S.
(2002) Delphilin: a novel PDZ and formin homology domain-containing
protein that synaptically colocalizes and interacts with glutamate receptor
2 subunit. J Neurosci, 22, 803-14.
67. Kojima Y., Xin K.-Q., Ooki T., Hamajima K., Oikawa T., Shinoda K., Ozaki T.,
Hoshino Y., Jounai N., Nakazawa M., Klinman D. & Okuda K. (2002) Adjuvant
effect of multi-CpG motifs on an HIV-1 DNA vaccine. Vaccine, 20, 2857-65.
768. Kobayashi N., Koshino T., Uesugi M., Yokoo N., Xin K.-Q., Okuda K.,
Mizukami H., Ozawa K. & Saito T. (2002) Gene marking in adeno-associatedvirus vector infected periosteum derived cells for cartilage repair. J
Rheumatol, 29, 2176-80.
69. Hamajima K., Hoshino Y., Xin K.-Q., Hayashi F., Tadokoro K. & Okuda K.
(2002) Systemic and mucosal immune responses in mice after rectal andvaginal immunization with HIV-DNA vaccine. Clin Immunol, 102, 12-8.
70. Yoshida T., Okuda K., Xin K.-Q., Fukushima J., Toda S., Hagiwara E.,
Hamajima K., Koshino T. & Saito T. (2001) Activation of HIV-1-specificimmune responses to an HIV-1 vaccine constructed from areplication-defective adenovirus vector using various combinations of
immunization protocols. Clin Exp Immunol, 124, 445-52.
71. Xin K.-Q., Urabe M., Yang J., Nomiyama K., Mizukami H., Hamajima K.,
Nomiyama H., Saito T., Imai M., Monahan J., Okuda K., Ozawa K. & Okuda K.
(2001) A novel recombinant adeno-associated virus vaccine induces along-term humoral immune response to human immunodeficiency virus.
Hum Gene Ther, 12, 1047-61.
72. Watabe S., Xin K.-Q., Ihata A., Liu L., Honsho A., Aoki I., Hamajima K.,
Wahren B. & Okuda K. (2001) Protection against influenza virus challenge
by topical application of influenza DNA vaccine. Vaccine, 19, 4434-44.
73. Tsuji-Yamada J., Nakazawa M., Takahashi K., Iijima K., Hattori S., Okuda K.,
Minami M., Ikezawa Z. & Sasaki T. (2001) Effect of IL-12 encoding plasmid
administration on tight-skin mouse. Biochem Biophys Res Commun, 280,
707-12.
74. Tadokoro K., Koizumi Y., Miyagi Y., Kojima Y., Kawamoto S., Hamjima K.,
Okuda K., Tanaka S., Onari K., Wahren B., Aoki I. & Okuda K. (2001) Rapid
and Wide-reaching delivery of HIV-1 env DNA vaccine by intranasal
administration. Viral Immunology, 14, 159-67.
75. Shigematsu T., Fukushima J., Oyama M., Tsuda M., Kawamoto S. & Okuda K.
(2001) Iron-Mediated regulation of alkaline proteinase production in
Pseudomonas aeruginosa. Microbiol Immunol, 45, 578-90.
76. Sasaki S., Takeshita F., Okuda K. & Ishii N. (2001) Mycobacterium Ieprae andleprosy: a conpedium. Microbiol Immunol, 45, 729-36.
77. Okuda K., Xin K.-Q., Haruki A., Kawamoto S., Kojima Y., Hirahara F., Okada
H., Klinman D. & Hamajima K. (2001) Transplacental genetic immunization
after intravenous delivery of plasmid DNA to pregnant mice. J Immunol, 167,
5478-84.
78. Okuda K., Ishihara K., Nakagawa T., Hirayama A., Inayama Y. & Okuda K.
8

(2001) Detection of Treponema denticola in atherosclerotic lesions. J Clin
Microbiol, 39, 1114-7.
79. Okuda K., Ihata A., Watabe S., Okada E., Yamakawa T., Hamajima K., Yang J.,
Ishii N., Nakazawa M., Okuda K., Ohnari K., Nakajima K. & Xin K.-Q. (2001)
Protective immunity against influenza a virus induced by immunization with
DNA plasmid containing influenza M gene. Vaccine, 19, 3681-91.
80. Liu L.-J., Watabe S., Yang J., Hamajima K., Ishii N., Hagiwara E., Onari K.,
Xin K.-Q. & Okuda K. (2001) Topical application of HIV DNA vaccine withcytokine-expression plasmids induces strong antigen-specific immune
responses. Vaccine, 20, 42-8.
81. Ishii N., Sugita Y., Liu L.-J., Watabe S., Toda S., Xin K.-Q. & Okuda K. (2001)
Immunologic charasterization of HIV-specific DNA vaccine. (sousetsu). J
Invest Dermatol, 6, 76-80.
82. Ara Y., Saito T., Takagi T., Hagiwara E., Miyagi Y., Sugiyama M., Kawamoto
S., Ishii N., Yoshida T., Hanashi D., Koshino T., Okada H. & Okuda K. (2001)
Zymosan enhances the immune response to DNA vaccine for humanimmunodeficiency virus type-1 through the activation of complement
system. Immunology, 103, 98-105.
83. Kusakabe K.-i., Xin K.-Q., Katoh H., Sumino K., Hagiwara E., Kawamoto S.,
Okuda K., Miyagi Y., Aoki I., Nishioka K. & Klinman D. (2000) The timing of
GM-CSF expression plasmid administration influences the Th1/Th2
response induced by an HIV-1 specific DNA vaccine. J. Immunol., 164,
3102-11.
84. Kawamoto S., Sonoda T., Ohtake A., Suzuki Y., Okuda K. & Tatibana M.
(2000) Alteration in arginine activation of N-acetylglutamate synthetase invitro by disulfide or thiol compounds. J. Mol. Catal., 10, 191-7.
85. Kato H., Bukawa H., Hagiwara E., Xin K.-Q., Hamajima K., Kawamoto S.,
Sugiyama M., Sugiyama M., Noda E., Nishizaki M. & Okuda K. (2000) Rectal
and vaginal immunization with a macromolecular multicomponent peptide
vaccine candidate for HIV-1 infection induces HIV-specific protective
immune responses. Vaccine, 18, 1151-60.
86. Hamajima K., Xin K.-Q., Fukushima J., Yang J., Honsho A., Nakazawa M.,
Yanoma S. & Okuda K. (2000) HIV-DNA vaccination following transfer of alarge number of activated T cells enhances immunoresponses against HIV-1.
Viral. Immunol., 13, 3-8.
87. Hagiwara E., Okubo T., Aoki I., Ohno S., Tsuji T., Ihata A., Ueda A., Shirai A.,
Okuda K., Miyazaki J. & Ishigatsubo Y. (2000) IL-12-encoding plasmid has abeneficial effect on spontaneous autoimmune disease in MRL/MP-lpr/lpr
9

mice. Cytokine, 12, 1035-41.
88. Asakura Y., Liu L.-J., Shono N., Hinkula J., Kjerrstrom A., Aoki I., Okuda K.,
Wahren B. & Fukushima J. (2000) Th1-biased immune responses induced by
DNA-based immunizations are mediated via action on professional
antigen-presenting cells to up-regulate IL-12 production. Clin Exp Immunol,
119, 130-9.
89. Arai H., Xin K.-Q., Hamajima K., Lu Y., Watabe S., Takahashi T., Toda S.,
Okuda K., Kudoh I., Suzuki M. & Okuda K. (2000) 8 Br-cAMP enhances both
humoral and cell-mediated immune responses induced by an HIV-1 DNA
vaccine. Gene Therapy, 7, 694-702.
90. Yamanaka A., Hirai K., Kato T., Naito Y., Inami S., Okuda K., Kaneko T. &Okuda K. (1999) Disinfectant effects of taisalite and taifresh ace containng
irgasan DP 300 against MRSA and HIV. Bulletin of Tokyo Dental College, 34,
167-71.
91. Xin K.-Q., Hamajima K., Hattori S., Cao X.-R., Kawamoto S. & Okuda K.
(1999) Evidence of HIV type 1 glycoprotein 120 binding to recombinant
N-methyl-D-aspartate receptor subunits expressed in a baculovirus system.
AIDS Res. Hum. Retrov., 15, 1461-7.
92. Xin K.-Q., Lu Y., Hamajima K., Fukushima J., Yang J., Inamura K. & Okuda K.
(1999) Immunization of RANTES Expression Plasmid with a DNA Vaccine
Enhances HIV-1-Specific Immunity. Clinical Immunology, 92, 90-6.
93. Xin K.-Q., Hamajima K., Sasaki S., Tsuji T., Watabe S., Okada E. & Okuda K.
(1999) IL-15 expression plasmid enhances cell-mediated immunity induced
by an HIV-1 DNA vaccine. Vaccine, 17, 858-66.
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Tarutani O. & Okuda K. (1991) Synthesis and examination of antigenicity offour hormonogenic sites and two non-hormonogenic sites of human
thyroglobulin. Mol Cell Endocrinol, 79, 93-8.
185.
Kawamoto S., Onishi H., Hattori S., Miyagi Y., Amaya Y., Mishina M. &Okuda K. (1991) Functional expression of the 1 subunit of the
AMPA-selective glutamate receptor channel, using a baculovirus system.
Biochem Biophys Res Commun, 181, 756-63.
186.
Inami S., Taniguchi N., Ishibashi K., Nagao T., Aoki I., Ishii N. & Okuda K.
(1991) Serum antibody directed against synthetic peptides derived fromHIV-1 protein sequence obtained from 26 Japanese HIV-1-infectedindividuals. AIDS, 5, 1140-1.
187.
Tanaka S., Nakajima S., Inoue S., Takamura Y., Aoki I. & Okuda K. (1990)
Genetic control by I-A subregion in H-2 complex of incidence of
streptozocin-induced autoimmune diabetes in mice. Diabetes, 39, 1298-304.
188.
Okuda K., Morihara K., Atsumi Y., Takeuchi H., Kawamoto S., Kawasaki
H., Suzuki K. & Fukushima J. (1990) Complete nucleotide sequence of thestructural gene for alkaline proteinase from Pseudomonas aeruginosa IFO
3455. Infect Immun, 58, 4083-8.
189.
Kawai T., Katoh K., Tani K., Okuda K. & Okubo T. (1990) HLA antigens inJapanese patients with central nervous system lupus. Tissue Antigens, 35,
45-6.
190.
Fukushima J., Takeuchi H., Tanaka E., Hamajima K., Sato Y., Kawamoto
S., Morihara K., Keil B. & Okuda K. (1990) Molecular cloning and partial DNA
sequencing of the collagenase gene of Vibrio alginolyticus. Microbiol
Immunol, 34, 977-84.
191.
Takahashi T., Mitsuda T. & Okuda K. (1989) An alternative
nonradioactive method for labeling DNA using biotin. Anal Biochem, 179,
77-85.
192.
Okuda K., Fukushima J., Kawamoto S. & Aoki I. (1989) Activition of I-A
gene products by A gene transfection using bovinepapilloma virus-vector
systems in H-2 antigens. In: Genes, Molecules, and Function (ed. C. S.
20

David), p. 275-82. Plenum Press, NY.
193.
Morihara K., Fukushima J. & Okuda K. (1989) Primary structure of
Pseudomonas aeruginosa elastase. A comparison with thermolysin.
Antibiot Chemother, 42, 36-41.
194.
Kawamoto S., Kaneko T., Mizuki N., Ohsuga A., Fukushima J., Amaya Y.,
Mori M. & Okuda K. (1989) Molecular cloning and nucleotide sequence of rat
brain argininosuccinate lyase cDNA with an extremely long 5'-untranslatedsequence: evidence for the identity of the brain and liver enzymes. Brain
Res Mol Brain Res, 5, 235-41.
195.
Hikawa N., Horie H., Kawakami T., Okuda K. & Takenaka T. (1989)
Introduction of macromolecules into primary cultured neuronal cells by
fusion with erythrocyte ghosts. Brain Res, 481, 162-4.
196.
Fukushima J., Yamamoto S., Morihara K., Atsumi Y., Takeuchi H.,
Kawamoto S. & Okuda K. (1989) Structural gene and complete amino acidsequence of Pseudomonas aeruginosa IFO 3455 elastase. J Bacteriol, 171,1698-704.
197.
Dairaku M., Tsuchie H., Ushijima H., Aoki I., Okuda K., Honda M., IkegamiN., Hachimori K., Matsuda J. & Kitamura T. (1989) Incidence and titer ofanti-rev antibody in HIV infection. AIDS, 3, 765-6.
198.
Atsumi Y., Yamamoto S., Morihara K., Fukushima J., Takeuchi H., Mizuki
N., Kawamoto S. & Okuda K. (1989) Cloning and expression of the alkaline
proteinase gene from Pseudomonas aeruginosa IFO 3455. J Bacteriol, 171,5173-5.
199.
Yanoma S., Aoki I., Ishii N., Tani K., David C.S. & Okuda K. (1988) The
role of autoreactive T-cell hybridomas from autoimmune model mice.
Immunology, 64, 113-9.
200.
Yamamoto S., Fukushima J., Atsumi Y., Takeuchi H., Kawamoto S.,
Okuda K. & Morihara K. (1988) Cloning and characterization of elastase
structural gene from Pseudomonas aeruginosa IFO 3455. Biochem Biophys
Res Commun, 152, 1117-22.
201.
Okuda K., Tani K., Ishigatsubo Y., Kato K., Atsumi Y., Kawai T., Ishii N.,
Aoki I. & Okubo T. (1988) Three deferent types of monoclonal anti-allotypic
antibodies against the teterminant of immunogloblin supergene family of
the antigen-specific suppressor T-cell factor. Yokohama Med. Bull., 39,
67-72.
202.
Ishii N., Aoki I., Ishii T., Mizuki N., Okuda K. & Nakajima H. (1988)
Suppressor T cells in mice made unresponsive to skin allografts. J Invest
Dermatol, 91, 333-5.
21

203.
Ishii N., Ichiyama S., Ishii T., Aoki I., Okuda K. & Nakajima H. (1988)
Genetic control of delayed-type hypersensitivity to D-penicillamine antigen.
Int Arch Allergy Appl Immunol, 85, 150-3.
204.
Fukushima J., Tani K., Atsumi Y., Hamajima K., Kawamoto S. & Okuda K.
(1988) Trans-activation of class II (I-A) gene by I-A gene transfection
using bovine papilloma virus as a shuttle vector system. J Immunol, 141,302-7.
205.
Ishii N., Kawaguchi H., Aoki I., Takahashi T., Okuda K. & Nakajima H.
(1987) Delayed-type hypersensitivity to allogeneic mouse epidermal cell
antigens. III. Analysis of suppressor cells. Exp Clin Immunogenet, 4, 48-55.
206.
Aoki I., Ishii N., Minami M., Misugi K., Dorf M.E. & Okuda K. (1987)
Analysis of alloantigen-specific suppressor T cells. Transplantation, 43,888-92.
207.
Aoki I., Ishii N., Minami M., Nagashima Y., Misugi K. & Okuda K. (1987)
Induction of suppressor T cells by intravenous administration of
monoclonal anti-I-A antibody. Transplantation, 44, 421-5.
208.
Tani K., Sakamoto H., Katoh K., Matsunagai K., Yamada S., Okuda K. &Handwerger B.S. (1986) Establishment of monoclonal antibodies which
possess the same characteristics as the naturally occurring thymocytotoxic
autoantibodies (NTA). Rheumatol Int, 6, 19-24.
209.
Takahashi T., Mitsuda T., Hikawa N., Ishii N. & Okuda K. (1986) A simple
and effective apparatus for Southern-, Northern-, and Western reactions andthe following procedures. Can J Med Tech, 48, 216-8.
210.
Takahashi T., Ishii N., Aoki I. & Okuda K. (1986) A simple and effective
technique for washing filter strips. Can J Med Tech, 48, 161-3.
211.
Sakata S., Okuda K., Aihara Y., Tanaka Y., Nakamura S., Komaki T.,
Tarutani O. & Miura K. (1986) Genetic control of the production ofanti-thyroid hormone antibodies in mice immunized with human
thyroglobulin. Immunol Invest, 15, 481-92.
212.
Kasai N., Arata S., Mashimo J., Okuda K., Aihara Y., Kotani S., Takada H.,
Shiba T., Kusumoto S., Imoto M., Yoshimura H. & Shimamoto T. (1986)
Synthetic Salmonella-type lipid A antigen with high serological specificity.
Infect Immun, 51, 43-8.
213.
Ishii N., Nakajima H., Aoki I., Ishii T., Takahashi T. & Okuda K. (1986)
Delayed-type hypersensitivity to allogeneic mouse epidermal cell antigens. I.
Lyt-1+2- T cells are important for DTH. Immunogenetics, 23, 351-6.
214.
Hagiya M., Davis D.D., Takahashi T., Okuda K., Raschke W.C. & Sakano
H. (1986) Two types of immunoglobulin-negative Abelson murine leukemia
22virus- transformed cells: implications for B-lymphocyte differentiation. Proc
Natl Acad Sci USA, 83, 145-9.
215.
Sakata S., Nakamura S., Komaki T., Aihara Y. & Okuda K. (1985)
Preparation of Ir-gene(s) of the production of anti-tyroid hormone
anti-bodies. In: Autoimmunity and thymus, p. 359-64. Academic Press.
216.
Saburi Y., Takahashi A., Takahashi T. & Okuda K. (1985) A ten-year
study of antibiotic susceptibility of Staphylococcus aureus at a children's
hospital. Yokohama Med. Bull., 36, 18-24.
217.
Saburi Y., Takahashi T. & Okuda K. (1985) Seasonal prevalence oferythema infectiosum. J Dermatol, 12, 375-6.
218.
Mashimo J., Yoshida M., Ikeuchi K., Hata S., Arata S., Kasai N., Okuda K.
& Takazoe I. (1985) Fatty acid composition and Shwartzman activity oflipopolysaccharides from oral bacteria. Microbiol Immunol, 29, 395-403.
219.
Katoh K., Matsunaga K., Ishii N., Okubo T. & Okuda K. (1985) Epidermal
cells bearing both I-A and I-E subregion antigens can induce hen egg whitelysozyme-specific T lymphocyte proliferation. J Dermatol, 12, 20-30.
220.
Kasai N., Arata S., Mashimo J., Okuda K., Aihara Y., Kotani S., Takada H.,
Shiba T. & Kusumoto S. (1985) In vitro antigenic reactivity of synthetic lipid
A analogues as determined by monoclonal and conventional antibodies.
Biochem Biophys Res Commun, 128, 607-12.
221.
Ishii N., Aoki I., Aihara Y., Hikawa N., Takahashi T. & Okuda K. (1985)
Analysis of hen egg white lysozyme (HEL)-specific delayed typehypersensitivity hybridomas. Hybridoma, 4, 311-8.
222.
Saburi Y., Uno F., Akatsuka K., Uno N., Kumon H., Takahashi T. & Okuda
K. (1984) Ultrastructures of leuco-adsorption on monolayers infected with
influenza virus. Microbiol Immunol, 28, 913-21.
223.
Okuda K., Saito H., Aihara Y., Minami M. & Tadokoro I. (1984)
4-Hydroxy-3-nitrophenyl (NP) acetyl-hapten specific lymphocyte
proliferation. I. Mice bearing Igh-1b allotype can cross-react with 4hydroxy-5-iodo-3-nitrophenyl (NIP) acetyl hapten. Microbiol Immunol, 28,
471-9.
224.
Okuda K., Nagaoka S., Katoh K., Matsunaga K., Ishigatubo Y., Minami M.
& Tani K. (1984) Abnormalities of third-order suppressor T cells in old (New
Zealand black x New Zealand white) F1 mice. Immunology, 53, 553-61.
225.
Nagatani T., Tanaka M., Nakajima H., Nagai R., Aihara Y., Matsunaga K.,
Katoh K., Minami M. & Okuda K. (1984) Establishment of T cell hybridomas
which produce suppressor factors specific to the hen egg-white lysozyme(HEL). Jpn J Exp Med, 54, 1-8.
23

226.
Sherr D.H., Minami M., Okuda K. & Dorf M.E. (1983) Analysis of T cellhybridomas. III. Distinctions between two types of hapten-specificsuppressor factors that affect plaque-forming cell responses. J Exp Med,
157, 515-29.
227.
Minami M., Okuda K., Furusawa S. & Dorf M.E. (1983) Analysis of T cellhybridomas. IV. Characterization of inducible suppressor cell hybridomas. J
Exp Med, 157, 1379-95.
228.
Matsunaga K., Tani K., Katoh K., Ishigatsubo Y., Iwaku T., Tadokoro I. &Okuda K. (1983) Genetic control of PQ prolongation of theelectrocardiogram in the mouse immunized with the killed group A
streptococci. J Immunogenet, 10, 31-9.
229.
Dorf M.E., Okuda K. & Minami M. (1983) Use of T cell hybridomas toanalyze a suppressor cell cascade. In: T Cell Hybridomas, p. 179-87. Cre
Press Roca Ronton.
230.
Aihara Y., Sakata S., Nakamura S., Kamikubo K., Tarutani O., Yamada S.,
Tadokoro I. & Okuda K. (1983) Genetic control of mouse antibody
production to human thyroglobulin. J Immunogenet, 10, 325-31.
231.
Aihara Y., Tadokoro I., Katoh K., Minami M. & Okuda K. (1983) T cellallotypic determinants encoded by genes linked to the immunoglobulin
heavy chain locus. I. Establishment of monoclonal antibodies against
allotypic determinants. J Immunol, 130, 2920-5.
232.
Taniguchi N., Usui M., Okuda K. & Matuhasi T. (1982) Hapten-pullulan
conjugate-induced CMI suppression: demonstration of a common pathway
of suppressor cells involving idiotypic interactions. J Immunol, 129,
1816-22.
233.
Okuda K., Ishii N., Ikezawa Z., Takahashi T., Arai K. & Tadokoro I. (1982)
Delayed-type hypersensitivity to hen egg-white lysozyme. I. The surface
phenotypes of suppressor T cells induced by intravenous injection oflysozyme-modified spleen cells, and their molecular interactions. Microbiol
Immunol, 26, 897-911.
234.
Minami M., Okuda K., Sunday M.E. & Dorf M.E. (1982) H-2K-, H-21- andH-2D-restricted hybridoma contact sensitivity effector cells. Nature, 297,
231-3.
235.
Matsunaga K., Katoh K., Takahashi T., Sakamoto H., Tani K., Okuda K.,
Tadokoro I. & Kitamura H. (1982) The experimental myocarditis of mice
immunized with group A streptococcal cytoplasmic membrane fraction
extracted from L-forms. Jpn J Exp Med, 52, 267-70.
236.
Dorf M.E., Okuda K. & Minami M. (1982) Dissection of a suppressor cell24

cascade. Curr Top Microbiol Immunol, 100, 61-7.
237.
Okuda K., Minami M., Furusawa M. & Dorf M.E. (1981) Analysis of T cellhybridomas. II. Comparisons among three distinct types of monoclonal
suppressor factors. J Exp Med, 154, 1838-51.
238.
Okuda K., Minami M., Ju S.T. & Dorf M.E. (1981) Functional associationof idiotypic and I-J determinants on the antigen receptor of suppressor T
cells. Proc Natl Acad Sci U S A, 78, 4557-61.
239.
Okuda K., Minami M., Sherr D.H. & Dorf M.E. (1981) Hapten-specific T
cell responses to 4-hydroxy-3-nitrophenyl acetyl. XI. Pseudogenetic
restrictions of hybridoma suppressor factors. J Exp Med, 154, 468-79.
240.
Minami M., Okuda K., Furusawa S., Benacerraf B. & Dorf M.E. (1981)
Analysis of T cell hybridomas. I. Characterization of H-2 and Igh- restricted
monoclonal suppressor factors. J Exp Med, 154, 1390-402.
241.
Ishii N., Ikezawa Z., Nagai R., Tani K., Ishigatsubo Y. & Okuda K. (1981)
Genetic control of contract hypersensitivity. II. Suppressor cells induced byintravenous injection of DNP-coupled syngeneic spleen cells possessing
thy-1 antigen, I-J determinant, Lyt-2+, 3+ antigen, FcR- and DNP-membranebinding receptor on their surfaces. Microbiol Immunol, 25, 63-70.
242.
Ikezawa Z., Sato M., Nagai R. & Okuda K. (1981) Cell surface expressionof I-A products is required for contact sensitivity induction bytrinitrophenyl-coupled epidermal cells. Microbiol Immunol, 25, 1335-44.
243.
Takahashi T., Nakatsuka S., Okuda K. & Tadokoro I. (1980) Preservationof bacterial L-forms by freezing. Jpn J Exp Med, 50, 313-8.
244.
Okuda K., Tani K., Ishigatsubo Y., Yokota S. & David C.S. (1980)
Antigen-pulsed neutrophils bearing Ia antigens can induce T lymphocyte
proliferative response to the syngeneic or semisyngeneic antigen-primed T
lymphocytes. Transplantation, 30, 368-72.
245.
Okuda K., Ishiwara K., Noguchi Y., Takahashi T. & Tadokoro I. (1980)
New type of antibody-enzyme conjugate which specifically kills Candida
albicans. Infect Immun, 27, 690-2.
246.
Okuda K., Ishii N., Ikezawa Z., Tani K. & Ishigatsubo Y. (1980) Genetic
control of contact hypersensitivity. I. I-A subregion as well as non-H-2 locicodes for the gene of 2,4-dinitro-1-fluorobenzene antigen. Eur J Immunol, 10,969-71.
247.
Okuda K., Neely B.C. & David C.S. (1979) Expression of H-2 and Ia
antigens on mouse peritoneal neutrophils. Transplantation, 28, 354-6.
248.
Okuda K., Sakata S., Atassi M.Z. & David C.S. (1979) Genetic control of
the immune response to hen's egg-white lysozyme in mice. I. Antibody and25

T-lymphocyte proliferative responses to the native protein. J Immunogenet,
6, 447-52.
249.
Okuda K., Twining S.S., David C.S. & Atassi M.Z. (1979) Genetic controlof immune response to sperm whale myoglobin in mice. II. T lymphocyte
proliferative response to the synthetic antigenic sites. J. Immunol., 123,
182-8.
250.
Okuda K., Christadoss P.R., Twining S., Atassi M.Z. & David C.S. (1978)
Genetic control of immune response to sperm whale myoglobin in mice. I. T
lymphocyte proliferative response under H-2-linked Ir gene control. J
Immunol, 121, 866-8.
251.
Okuda K., Neely B.C., Hilgers J. & David C.S. (1978) Immune
response-associated antigens on mouse leukemia cells. II. Anti-Ia sera
inhibit the MLR reaction between normal GR spleen cells and syngeneic
spleen cells of GRSL tumor-bearing mice. Transplantation, 26, 300-3.
252.
Okuda K. & David C.S. (1978) A new lymphocyte-activating determinantlocus expressed on T cells, and mapping in I-C subregion. J Exp Med, 147,
1028-37.
253.
Okuda K., Cullen S.E., Hilgers J. & David C. (1978) Immune
response-associated antigens on mouse leukemia cells. I. Detection of Ia
antigens on GRSL cells. Transplantation, 26, 153-6.
254.
David C.S., Schwartz B.J., Okuda K., Cullen S.E., Hilger J. & Schwartz
R.H. (1978) Expression of Ia antigens on I cell leukemias and thymocytes. In:
Ir Genes and Ia Antigens (ed. H. E. McDevitt), p. 111-20. Academic Press.
255.
Saburi Y., Okuda K., Takahashi T. & Tadokoro I. (1977) Electron
microscopic study of hemadsorption on vaccinia virus infected cells.
Microbiol Immunol, 21, 593-600.
256.
Okuda K., David C.S. & Shreffler D.C. (1977) The role of gene products of
the I-J subregion in mixed lymphocyte reactions. J Exp Med, 146, 1561-73.
257.
Okuda K., Takahashi T., Tadokoro I. & Eda T. (1977) Studies on theminimum reproducible unit of staphylococcal L-forms. Microbiol Immunol,
21, 1-10.
258.
Takahashi T., Suzuki K., Okuda K., Tadokoro I. & Saburi Y. (1976)[Ultrastructural study of the adsorption of lymphocytes on cells infected byvacinnia virus] Etude ultrastructurale de l'adsorption de lymphocytes surles cellules infectees par du virus vaccinal. C R Seances Soc Biol Fil, 170,
1126-8.
259.
Sekido M., Ohtani T., Okuda K. & Tadokoro I. (1976) Studies on HLA
antigens in patients with Behcet's syndrome. Yokohama Med. Bull., 27, 1-8.
26

260.
Okuda K., Tadokoro I. & Noguchi Y. (1976) Phagocytosis of Candida
albicans by neutrophils. In: Yeast and Yeast-like Organisms in Medical
Science, p. 339-45.
261.
Okuda K., Takahashi T., Tadokoro I. & Noguchi Y. (1976) Effects ofcytochalasin B and dibutyryl cyclic AMP on intraleukocytic bactericidal
activity. Jpn J Exp Med, 46, 101-10.
262.
Tadokoro I. & Okuda K. (1975) The role of contractile microfilaments in
the intracellular microbiodical activity of neutrohils. Yokohama Med. Bull.,
26, 153-9.
263.
Okuda K., Tadokoro I. & Noguchi Y. (1975) Regulation of intracellularbactericidal activity. In: Ist ISC-IAMS Proceedings, Vol. 3, p. 197-203.
264.
Okuda K. (1975) Effects of cytochalasin B on the intrcellular bactericidal
activity of human neutrophils. Antimicrob Agents Chemother, 7, 736-41.
265.
Okuda K., Tadokoro I. & Noguchi Y. (1975) The metabolic andphagocytic activities of leukocytes from patients receiving corticosteroid
and radiation therapy, and patients with bacterial infections. Jpn J Microbiol,
19, 105-13.
266.
Okuda K., Okamoto R., Noguchi Y. & Tadokoro I. (1975) An investigationof leukocyte function and phagocytosis of immune complexes in patientswith rheumatoid arthritis. Jpn J Exp Med, 45, 1-10.
267.
Okuda K., Tadokoro I. & Noguchi Y. (1975) Intraleukocytic bactericidal
activity in patients receiving corticosteroid and radiation therapy, and inpatients with diabetes mellitus. Jpn J Microbiol, 19, 97-103.
268.
Okuda K., Tadokoro I. & Noguchi Y. (1974) Phagocytosis of Candida
albicans by neutrophils. In: The Proceedings of Yeast and Yeast-like
Organisms, p. 138-9.
269.
Okuda K., Tadokoro I. & Sekido M. (1974) The NBT test in Behcet's
syndrome. N Engl J Med, 290, 915-6.
270.
Okuda K., Tadokoro I. & Noguchi Y. (1974) Nitroblue tetrazolium(NBT)-dye test and the myeloperoxidase reaction of human leukocytes. Jpn
J Microbiol, 18, 337-42.
271. Okuda K., Tadokoro I. & Noguchi Y. (1972) Phagocytosis of Candida
albicans by Neutrophils. In: Proceedings of the Second International
Specialized Symposium on Yeast (ed. K. Iwata), p. 339-42. University ofTokyo Press, Tokyo.

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