Tsukuba	  Clinical	  Research	  &	  Development	  Organiza=on	  (T-­‐CReDO)	  T-­‐CReDO	  is	  responsible	  to	  develop	  the	  medical	  seeds	  born	  in	  Tsukuba	  Science	  City.	
There  are  ca.  300  research  institutes  including  29  National  Research  Institutes  and  ca.  20,000  researchers  are  working  in  Tsukuba.

University	  of	  Tsukuba	  is	  one	  of	  ten	  Clinical	  and	  Transla=onal	  Research	  Core	  Centers.	

Hokkaido Univ.	
Asahikawa Med. Univ.	
Sapporo Med. Univ.	
Kyoto	  Univ.	

Tohoku	  Univ.	

Nagoya	  Univ.	

Okayama	  Univ.	

University	  of	  Tsukuba	Kyushu	  Univ.	

Univ.	  of	  Tokyo	

Osaka	  Univ.	

Keio	  Univ.	

T-­‐CReDO	  provides	  one-­‐stop	  service	  to	  researchers	  and	  	  facilitates	  prac=cal	  applica=on.	
Hands-­‐on	  support	  for	  from	  the	  IP	  and	  research	  strategies	  to	  clinical	  development	  and	  exit	  strategy		  Established	  in	  June,	  2015	  As	  of	  June	  1,	  2019	

Staﬀ	
DirectorCouncilConsult.+of+Develop.+Strategy+
Univ.+Res.+Administrators +++Res.+Promo3on,+Pipeline+Man.,+++IPs,+Pub.EPriv.+Partnering,++
Dept.+of+R&D+Management+
Budget+Acquiring,+Financial+
Aﬀairs,+Contract,+
Secretary+for+Inside+CommiXees++Transla3onal+Res.+&+
Educa3on+Center	QA+Oﬃce

Clinical+Research+Service+Center+
Ctr.+for+Integra3ve+
Medicine+and+Engineering+ CIME)+
Located+within+Hosp.+Word+
Building++
1) Feasibility+Study+of+
Medical+Devices+
2) Phase+1+study+
3) Prepara3on+of+ est+
materials+
4) Lab.+Space+

Seed$Incuba+on$and$
Educa+on/Training$

Central+Coordina3ng++
Unit+
Consulta3on,+Opera3on,+
Data+management,+
Monitoring,+
BioEsta3s3cs,+
Safety+Informa3on+

Feasibility$Study$

Seeds+Review+CommiXee

Network+Oﬃce++

Clin.+Res.+Coordinator,+
Management.+and+
Dispensi+of+Test+Drugs

Regional+NW,+
IRB+Oﬃce,+
Natl.+Univ.+Hosp.++ Ethics+Comm.+++Alliance,+Oﬃce,+
Public+Awareness+ Administra3on+

CommiXee+for+Adv.+Med.+InEhouse+Fund

Small%
Molecules

An.bodiesPartneringIndustry(Basic(Research(Industry(Exploratory(Research(

Clinical(Trials(

Outside'Researchers

Inside'Researchers
Periodical/Collec)on/and/ad/hoc.

T@CReDO/Dept./of/R&D/Management/

Periodical//and/Ad/hocRegistra)on

Advanced(MedicineConsulta)on

Advance%medicine%(HAL,%BNCT,%
Gene%Therapy,%Regenera.ve%Medicine),%Orphan/Intractable%Diseases

Pipeline/Manage.
Data/BaseConsulta)on
Seeds/Review/
CommiFee/

IP/&/Research/Strategy/Consulta)onPartnering/w//industries
Support/in/Appl./to/AMEDPharmaceu)cal/Aﬀairs

Clinical/Development/Consulta)on

Non@clinical/Studies
Clinical/Studies

Support/Consulta)on
Support/by/CIME/or/Clin./Res./Prom./Ctr./

Industry(Clinical(Trials(Approval,(Marke?ng(Seeds/Support/Dept./Academia@Industry/Collab.

StartupLicense/Out	 Research/Stage	
/Pre@/clinical/and/Clinical/Stage

Technology$transferIndustry(Non;clinical(Studies● Pipeline (as of February, 2019)	  • Pharmaceu=cals・Med.	  Devices・Regen.	  Med.	  
• Total	  No.	  of	  seeds:	  148	  	  	  	  	  	  	  	  	  in	  A	  (Exploratory)	  :	  90	  	  	  	  	  	  	  	  	  	  	  	  	  	  	  	  	  in	  B	  (Non-­‐Clinical)	  :	  36	  	  	  	  	  	  	  	  	  	  	  	  	  	  	  	  	  in	  C	  (Clinical	  POC)	  :	  22	  Seeds	  Registra=on	  and	  Consultaion	  Fow	

The$principle$is$to$iden/fy$the$Clinical$Needs,$to$make$Target$Product$Proﬁle$(TPP)$and$
the$Technology$Transfer$as$early$as$possible$by$promo/ng$Open$Innova/on.$(Discovery)

Admin.+Oﬃce+

Conduct$of$Clinical$Trials$

Project+Review+CommiXee

Exploratory
Non;clinical(Research( IPsStudies((Inven?on)

Pipeline	

Site+Coordina3ng++Unit

Strategy	  for	  Technology	  Transfer	

Basic(Research(● Total No. of full time staff: 71	  • No.	  of	  Facaul=es:	  17	  • No.	  of	  staﬀ	  who	  has	  the	  experience	  	  	  	  	  	  	  	  	  	  	  	  	  	  	  	  	  	  in	  Pharmaceu=cal	  Co.	  R&D:	  14	  	  	  	  	  	  	  	  	  	  	  	  	  	  	  	  	  in	  Medical	  Device	  Co.	  R&D:	  1	  	  	  	  	  	  	  	  	  	  	  	  	  	  	  	  	  in	  MHLW	  and	  PMDA:	  5	  Partnering'w/'Industries'(To'obtain'private'fund)'Collab./w//URA

To'obtain'AMED'funds'(Public'fundProject'Review'CommiGee
T@CReDO/Promo)on/&/Educa)on/Ctr.

Seeds'Incubator''w/'tutors'or''mentors

T@CReDO/
CIME,/Cent./Coord./U./

Support'for'Feasibility'Study'and'Clin.'Research