CaBP19 – Vanderbilt University

The 19 th International Symposium on Calcium Binding Proteins
and Calcium Function in Health and Disease
Welcome to Nashville and Vanderbilt University for the 19th International Symposium on Calcium-Binding Proteins andCalcium Function in Health and Disease (CaBP19). My team and I look forward to hosting you in the tradition of thisesteemed series of symposia. We also hope you have an opportunity to see some of our city, one of the fastest growing
metropolitan areas in the United States.
The International Advisory Committee made clear the importance of maintaining the molecular focus that has characterized
all CaBP meetings. In keeping with the strong structural biology research focus of your hosts, this symposium emphasizes themolecular and structural biology and biochemical and biophysical aspects of calcium signaling, in addition to featuring leading
scientists in cell biology and medical sciences. We have an illustrious group of speakers, complemented by a cadre of leading
experts serving as session chairs. We are fortunate to count among our session chairs, two founding members of the CaBP
series: Ernesto Carafoli and Claude Klee. We have also planned a very special session on Sunday at 11:00 am, where
breakthrough structures of the ryanodine receptor determined using phenomenal new single particle cryo electron
microscopy technology will be presented, followed by a round table discussion.
One important aspect of the CaBP series of symposia is the avoidance of parallel sessions. Instead scientists from different
backgrounds from physical chemistry to medicine listen to the same talks and engage in lively and very fruitful discussion that
stimulates cross-disciplinary thinking and new collaborations. A second important aspect is the promotion of scientists justbeginning to launch their careers in our field. This includes the selection of 20 speakers to give short talks, chosen fromposter abstracts. We also have a strong poster presence and will include two new events: the poster flash and “meet thescientists” lunch sessions. This promises to be a very exciting meeting with excellent opportunities for interactions amongscientists in diverse areas of calcium signaling.
Walter Chazin

1

CaBP19 – Vanderbilt University

MEETING INFORMATIONAll sessions, meals and poster sessions will take place on the Vanderbilt University campus. Limited parking is available in the
Terrace Garage. A campus map and driving directions are available on page 9 of this program, and a list of taxi services arelisted on page 10. Accommodations are in the Moore House on the Kissam Quad. Sessions and breaks will take place inFeatheringill Hall. Poster sessions and meals are in Rand Hall/Sarratt Student Center. Dinner on Sunday night will be servedin the Kissam Center on the Kissam Quad. The banquet will be held in the Student Life Center.
MEALS
Please note that breakfast, lunch and dinner served in Rand Hall must commence within 20 minutes of the designated start
time. Diners may stay in the facility as long as they like once the meal has been served.
SPEAKER INFORMATIONAll speakers must load presentations onto a single computer just before the start of the respective session. Plenary session
speakers are allotted 20 minutes for presentation plus 5 minutes for discussion. Invited session speakers are allotted 15
minutes for presentation plus 5 minutes for discussion. Abstract selected short talks are allotted 12 minutes for presentation
plus 3 minutes for discussion.
POSTER SESSIONS & ABSTRACTS
Poster boards are numbered and correspond to the page listing in the Abstract Book, which is available for download on the
CaBP19 website: http://structbio.vanderbilt.edu/cabp19/program
Odd numbers will present during Poster Session #1 on Sunday, May 31. Even numbers will present during Poster Session #2
on Monday, June 1.
WI-FI
Guests may use the unsecured network “vummiv.” Choose “other network” from your wireless menu and enter “vummiv” toconnect.
CHECK-IN/CHECK-OUT PROCEDURES
Check-in Times: May 30, 11:00 am – 4:00 pm
Check-out Times: June 3, 11:30 am – 2:30 pm
To arrive/depart outside of this time frame, please call 615-343-8699 and select Option #1 when you arrive or prior to yourdeparture for check-in or check-out at the campus residence.
Room payments for May 29 arrivals ($45) must be paid directly to Karen Davis. Do not pay the check-in staff.
Check-in & check-out occurs at the residence hall (address below)
RESIDENCE HALL
Housing is provided in the Moore House at Kissam Quad located at 2101 West End Avenue.

2

CaBP19 – Vanderbilt University

PROGRAM OVERVIEWSaturday, May 30, 2015
3:30 – 4:00 pm
4:00 – 5:00 pm
5:00 – 6:30 pm
6:30 – 8:00 pm

Introductory remarks
Ebashi Lecture: David MacLennan, University of Toronto
Poster Flash
Dinner (dinner served 6:30 – 6:50 pm, attendees may stay in cafeteria until 8:00 pm)

Sunday, May 31, 2015
7:30 – 7:50 am
9:00 – 10:40 am
10:40 – 11:00 am
11:00 – 12:40 pm
12:50 – 2:30 pm
2:30 – 4:10 pm
4:10 – 4:30 pm
4:30 – 6:30 pm
6:30 – 8:00 pm

Breakfast served (attendees may stay in cafeteria until 9:00 am)
Session 1 – Calmodulin
Break
Session 2 – Breakthrough CryoEM structures of RyRs
Lunch (lunch served 12:50 – 1:10 pm, lunch break lasts until 2:30 pm)
Session 3 – Imaging/Detecting Ca Signals
Break
Poster Session #1
Dinner (dinner served in Kissam Center)Monday June 1, 2015
7:30 – 7:50 am
9:00 – 10:40 am
10:40 – 11:00 am
11:00 – 12:40 pm
12:50 – 2:30 pm
2:30 – 4:10 pm
4:10 – 4:30 pm
4:30 – 6:30 pm
6:30 – 8:00 pm

Breakfast served (attendees may stay in cafeteria until 9:00 am)
Session 4 – Interesting CaBP structures: Ca2+-gated membrane proteins
Break
Session 5 – Membrane associated CaBPs
Lunch (lunch served 12:50 – 1:10 pm, lunch break lasts until 2:30 pm)
Session 6 – S100 proteins
Break
Poster Session #2
Dinner (dinner served 6:30 – 6:50 pm, attendees may stay in cafeteria until 8:00 pm)

Tuesday, June 2, 2015
7:30 – 7:50 am
9:00 – 10:40 am
10:40 – 11:00 am
11:00 – 12:40 pm
12:50 – 2:30 pm
2:30 – 4:10 pm
4:10 – 4:30 pm
4:30 – 5:30 pm
5:30 – 6:30 pm
7:00 – 10:00 pm

Breakfast served (attendees may stay in cafeteria until 9:00 am)
Session 7 – CaBP reengineering and design
Break
Session 8 – Store-operated calcium entry (SOCE): players and mechanisms
Lunch (lunch served 12:50 – 1:10 pm, lunch break lasts until 2:30 pm)
Session 9 – Immune Response
Break
Closing Plenary Lecture: Richard Tsien, New York University
General Assembly
Banquet (Dinner is only provided for those attending the banquet.)

Wednesday, June 3, 2015
7:30 – 7:50 am
8:45 – 10:25 am
10:25 – 10:45 am
10:45 – 12:25 pm
12:25 – 12:45 pm
12:45 pm

Breakfast served (attendees may stay in cafeteria until 8:45 am)
Session 10 – Calcineurin
BreakSession 11 – Neurological Diseases
Awards and Closing Remarks
Box lunches available for takeaway

3

CaBP19 – Vanderbilt University

CaBP19 SESSION CHAI RS
Ernesto Carafoli, Ph.D.; Venetian Institute of Molecular Medicine; Padua, Italy
Ebashi Lecture and Closing Plenary Lecture
Madeline Shea, Ph.D.; University of Iowa; Iowa City, Iowa, USA
Session 1 – Calmodulin
Poul Nissen, Ph.D.; Aarhus University; Aarhus C, Denmark
Wayne Chen, Ph.D.; University of Calgary; Calgary, Alberta, Canada
Session 2 – Breakthrouth Cryo EM structures of RyRs
Katsuhiko Mikoshiba, M.D., Ph.D.; RIKEN Brain Institute; Wako, Saitama, Japan
Session 3 – Imaging/Dectecing Ca signals
Joachim Krebs, Scientist Emeritus; NMR based Structural Biology MPI for Biophysical Chemistry; Goettingen, Germany
Session 4 – Interesting CaBP structures: Ca2+gated membrane proteins
Volker Gerke, Ph.D.; University of Muenster; Muenster, Germany
Session 5 – Membrane associated CaBPs
David J. Weber, Ph.D.; University of Maryland; Baltimore, Maryland, USA
Session 6 – S100 Proteins
Robert H. Kretsinger, Ph.D.; University of Virginia; Charlottesville, Virginia, USA
Session 7 – CaBP reengineering and design
Mitsu Ikura, Ph.D.; Princess Margaret Cancer Centre/University of Toronto; Toronto, Ontario, Canada
Session 8 – Store-operated calcium entry (SOCE): players and mechanisms
Michael Lenardo, M.D.; National Institute of Allergy and Infectious Diseases; Bethesda, Maryland, USA
Session 9 – Immune Response
Claude Klee, Scientist Emeritus; National Institute of Health; Bethesda, Maryland, USA
Session 10 – Calcineuren
Jacek Kuznicki, Ph.D.; International Institute of Molecular and Cell Biology; Warsaw, Poland
Session 11 – Neurological diseases

SATURDAY ● MAY 30, 2015
Introductory Remarks
3:30 – 4:00 pm
Featheringill Hall Auditorium
Walter Chazin, Vanderbilt University; Nashville, Tennessee, USA
Ebashi Lecture
4:00 – 5:00 pm
Ernesto Carafoli, Session ChairDavid MacLennan, University of Toronto; Toronto, Ontario, Canada
Sarcoplasmic Reticulum Calcium Binding Proteins in Health and Disease
Poster Flash

5:00 – 6:30 pm

Dinner

6:30 – 8:00 pm

Rand Hall / Sarratt Student Center

4

CaBP19 – Vanderbilt University

SUNDAY ● MAY 31, 2015
Breakfast

7:30 – 8:30 am

Rand Hall / Sarratt Student Center

Session 1
9:00 – 10:40 am
Featheringill Hall Auditorium
Calmodulin – Madeline Shea, Session ChairJohn Putkey, Ph.D.; UT Health Medical School; Houston, Texas, USA
The Molecular Mechanism of Intrinsically Disordered Regulators of CaM Signaling
Madeline Shea, Ph.D.; University of Iowa; Iowa City, Iowa, USA
One CaM to Bind Them: Calmodulin Discriminates Among Nine Human Voltage-Gated Sodium Channels
Manu Ben Johny; Johns Hopkins University; Baltimore, Maryland, USA
Conservation of CaM Regulation Across Voltage-Gated Calcium and Sodium Channels
Christopher N. Johnson; Vanderbilt University; Nashville, Tennessee, USA
Ca2+ Regulation of the Human Cardiac Sodium Channel Nav1.5: Calmodulin Interacting with the Fast
Inactivation Gate and Effects of Disease Associated Mutations
Yuequan Shen; Nankai University; Tianjin, China
Calcium Signaling Dynamically Control Chaperone System in Mitochondria to Regulate Leaf SenescenceBreak

10:40 – 11:00 am

Session 2
11:00 – 12:40 pm
Featheringill Hall Auditorium
Breakthrough Cryo EM structures of RyRs – Poul Nissen and Wayne Chen, Session Chairs
Poul Nissen, Ph.D.; Aarhus University; Aarhus C, Denmark
Wayne Chen, Ph.D.; University of Calgary; Calgary, Alberta, Canada
Nieng Yan, Ph.D.; Tsinghua University; Beijing, China
Structural basis for the long range allosteric regulation and high ion conductance of the ryanodine receptor
RyR1
Oliver Clarke, Ph.D.; Columbia University; New York, New York, USA
Structural insights into ryanodine receptor gating
Rouslan Efremov, Ph.D.; VIB Structural Biology Research Center; Brussels, Belgium
Structure and dynamics of ryanodine receptor
Round Table Discussion
Lunch

12:50 – 2:30 pm

Rand Hall / Sarratt Student Center

Session 3
2:30 – 4:10 pm
Featheringill Hall Auditorium
Imaging/Detecting Ca Signals – Katsuhiko Mikoshiba, Session Chair
Jonathan Lederer, Ph.D.; University of Maryland; Baltimore, Maryland, USA
Mechano-chemo transduction: X-ros-dependent Ca2+ signaling in heart
Ian Parker, Ph.D.; University of California Irvine; Irvine, California, USA
Imaging and localizing IP3-evoked calcium signals and IP3 receptors at the single-channel level
Takeharu Nagai, Ph.D.; Osaka University; Osaka, Japan
Genetically-encoded tools to optically control and image calcium dynamics
Erica Shannon; Vanderbilt University; Nashville, Tennessee, USA
Calcium Dynamics as a Potential Readout of Mechanotransduction at Epithelial Wounds
Shigenori Inagaki; Osaka University; Osaka, Japan
Genetically-encoded Chemiluminescent Indicator Applicable in Milli-second Voltage Phenomena
Break

4:10 – 4:30 pm

Poster Session #1

4:30 – 6:30 pm

Sarratt Student Center, Room 220

Dinner

6:30 – 8:00 pm

Kissam Center on the Kissam Quad

5

CaBP19 – Vanderbilt University

MONDAY ● JUNE 1, 2015
Breakfast

7:30 – 8:30 am

Rand Hall / Sarratt Student Center

Session 4
9:00 – 10:40 am
Featheringill Hall Auditorium
Interesting CaBP structures: Ca2+-gated membrane proteins – Joachim Krebs, Session Chair
Youxing Jiang, Ph.D.; UT Southwestern; Dallas, Texas, USA
Structural study of a plant RCK-regulated nuclear membrane channel
Raimund Dutzler, Ph.D.; University of Zurich; Zurich, Switzerland
Structure and function of Ca2+ activated TMEM16 channels and scramblases
Stephen Long, Ph.D.; Memorial Sloan Kettering Cancer Center; New York, New York, USA
Structure and insights into the function of the bestrophin calcium-activated chloride channel
Alexander Dizhoor; Salus University; Elkins Park, Pennsylvania, USA
Targeting Photopreceptor Membrane Guanylyl Cyclase (RetGC) by Calcium-sensor Proteins: Role of Protein
Domains and the Effects of Mutations Linked to Congenital Blindness
Anand Sharma; Centre for Cellular & Molecular Biology; Hyderabad, India
Identification of SCGN as a Cytosolic Insulin Binding Protein
Break

10:40 – 11:00 am

Session 5
11:00 – 12:40 pm
Featheringill Hall Auditorium
Membrane associated CaBPs – Volker Gerke, Session Chair
Stephen Moss, Ph.D.; University College London; London, England
Integrated functions for annexins in the mammalian retina
James B. Ames, Ph.D.; University of California Davis; Davis, California, USA
Calmodulin Capping of PSD-95 Triggers its Postsynaptic Release
Edwin R. Chapman, Ph.D.; University of Wisconsin - Madison; Madison Wisconsin, USA
Engineering Ca2+-sensors for exocytosis
Katarzyna Zoltowska; Harvard Medical School/Massachusetts General Hospital; Charlestown, Massachusetts, USA
Synaptotagmin 1 in Alzheimer's Disease - Guard or Partner in Crime?
Haifeng Zheng; University of Nevada Reno; Reno, Nevada, USA
Na+/Ca2+ Exchange Contributes to the Regulation of the Pacemaker Activity of Interstitial Cells
Lunch

12:50 – 2:30 pm

Rand Hall / Sarratt Student Center

Session 6
2:30 – 4:10 pm
Featheringill Hall Auditorium
S100 proteins – David J. Weber, Session ChairDavid J. Weber, Ph.D.; University of Maryland; Baltimore, Maryland, USA
Structure, function, and inhibition of S100B in malignant melanoma
Mariam Grigorian, M.D., Ph.D.; University of Copenhagen; Copenhagen, Denmark
Metastasis-inducing S100A4 in the pro-inflammatory pathways of Non-Communicable Diseases
Julia Ritterhoff, Ph.D.; University of Heidelberg; Heidelberg, Germany
S100A1 in cardiovascular health and disease: From molecule to therapy
Ulrike Stein; Charite - Universitatsmedizin Berlin; Berlin, Germany
S100A4: Key Player in Cancer Metastasis and Signaling-based Interventions for Metastasis Restriction
Marie-Luce Bochaton-Piallat; University of Geneva; Geneva, Switzerland
S100A4 Promotes Smooth Muscle Cell Phenotypic Transition. Implications in Atherosclerosis
Break4:10 – 4:30 pm

Poster Session #2

4:30 – 6:30 pm

Sarratt Student Center, Room 220

Dinner

6:30 – 8:00 pm

Rand Hall / Sarratt Student Center

6

CaBP19 – Vanderbilt University

TUESDAY ● JUNE 2, 20 15
Breakfast
7:30 – 8:30 am
Rand Hall / Sarratt Student Center
Session 7
9:00 – 10:40 am
Featheringill Hall Auditorium
CaBP reengineering and design – Robert Kretsinger, Session Chair
Jenny Yang, Ph.D.; Georgia State University; Atlanta, Georgia, USA
Design calcium binding proteins for molecular imaging
Gary S. Shaw, Ph.D.; University of Western Ontario; London, Ontario, Canada
Come Together: Designing S100 Proteins to Identify New Biological Complexes
Yogendra Sharma, Ph.D.; Centre for Cellular & Molecular Biology; Hyderabad, India
Ca2+-binding beta gamma-crystallins: An affair that didn't last
Masayuki Nara; Tokyo Medical and Dental University; Tokyo, Japan
Infared Studies on the Ca2+-Bound Coordination Structure of Synthetic Peptide Analogues of the Ca2+Binded Site
Belinda Pastrana-Rios; University of Puerto Rico; Rincon, Puerto Rico
Novel Centrin-PRP40 Complex: Its Molecular Biophysical Characterization and Crystal Screens
Break10:40 – 11:00 am
Session 8
11:00 – 12:40 pm
Featheringill Hall Auditorium
Store-operated calcium entry (SOCE): players and mechanisms – Mitsu Ikura, Session Chair
Patrick Hogan, Ph.D.; La Jolla Institute for Allergy & Immunology; La Jolla, California, USA
The mechanics of STIM-ORAI communication
Stefan Feske, Ph.D.; New York University; New York, New York, USA
STIM1-mediated Ca2+ influx controls immune regulation and inflammation in chronic infection
Natalia Prevarskaya, Ph.D; Lille University of Science and Technology; Lille, France
Calcium and calcium channels in initiation and progression of prostate cancer
Alexey Shalygin; Institute of Cytology, Russian Academy of Sciences; St. Petersburg, Russia
Endogenous Store-operated Calcium Channels Regulated by STIM2 Proteins in HEK293 Cells
Bernard T. Drumm; University of Nevada Reno; Reno, Nevada, USA
The Role of Ca2+ Influx in Spontaneous Ca2+ Wave Propagation in Interstitial Cells of Cajal from the Rabbit
UrethraLunch
12:50 – 2:30 pm
Rand Hall / Sarratt Student Center
Session 9
2:30 – 4:10 pm
Featheringill Hall Auditorium
Immune Response – Michael Lenardo, Session Chair
Michael Lenardo, M.D.; National Institute of Allergy and Infectious Diseases; Bethesda, Maryland, USA
Mg2+ as a second messenger revealed by a human immunodeficiency
Anjana Rao, Ph.D.; La Jolla Institute for Allergy & Immunology; La Jolla, California, USA
Opposing transcriptional programs driven by calcium, calcineurin and NFAT in T cells
Eric Skaar, Ph.D.; Vanderbilt University; Nashville, Tennessee, USA
The battle for metal between bacterial pathogens and their hosts
Veronique Schenten; University of Luxembourg; Luxembourg
Regulation of the Neutrophil NADPH Oxidase and Release of S100A8/A9
Anne Bresnick; Albert Einstein College of Medicine; New York, New York, USA
Regulation of Macrophage Motility and Invasion by S100A4
Break
4:10 – 4:30 pm
Closing Plenary Lecture 4:30 – 5:30 pm
Ernesto Carafoli, Session Chair
Richard W. Tsien, Ph.D.; New York University; New York, New York, USA
Multiple roles of calmodulin in tuning cellular function and learning and memory
General Assembly
5:30 – 6:30 pm
Featheringill Auditorium
Banquet7:00 – 10:00 pm
Student Life Center, Ballroom A

7

CaBP19 – Vanderbilt University

WEDNESDAY ● JUNE 3, 2015
Breakfast

7:30 – 8:30 am

Rand Hall / Sarratt Student Center

Session 10
8:45 – 10:25 am
Featheringill Hall Auditorium
Calcineurin – Claude Klee, Session ChairMark Dell'Acqua, Ph.D.; University of Colorado School of Medicine; Aurora, Colorado, USA
Calcineurin regulation of neuronal calcium channel activity and signaling to the nucleus
Trevor Creamer, Ph.D.; University of Kentucky College of Medicine; Lexington, KY, USA
Disorder in calcineurin activation
Gabriela Caraveo-Piso, Ph.D.; MIT; Cambridge, Massachusetts, USA
FKBP12 determines calcineurin substrate selection: implications to synucleinopathies
Cecilia Andresen; Linkoping University; Linkoping, Sweden
Characterization of Structure, Dynamics and Calcium Binding of Plasmodium falciparum CDPK3
Yuya Fujiwara; Okayama University; Okayama City, Japan
Analysis of Distinct Roles of CaMKK Isoforms Using STO-609-Resistant Mutants in Living Cells
Break

10:25 – 10:45 am

Session 11
10:45 – 12:25 pm
Featheringill Hall Auditorium
Neurological Diseases – Jacek Kuznicki, Session Chair
Grace E. Stutzman, Ph.D.; Rosalind Franklin University; North Chicago, Illinois, USA
Upregulated Ryanodine Receptor Activity Underlies Alzheimer's Disease Pathology from Molecular to
Network Levels
Victoria Bolotina, Ph.D.; Boston University; Boston, Massachusetts, USA
Novel Calcium Signaling Root of Parkinson's Disease
Jacek Kuznicki, Ph.D.; International Institute of Molecular and Cell Biology; Warsaw, Poland
In search for models of sporadic Alzheimer's disease
Kazunori Kanemaru; University of Tokyo; Tokyo, JapanNew Calcium Imaging Methods for the Visualization of Local Activities of Astrocytes in vivo
Maria Ryazantseva; Institute of Cytology, Russian Academy of Sciences; St. Petersburg, Russia
Familial Alzheimer's Disease Mutation in Presenilin-1 Gene Leads to an Abnormal Store-operated Calcium
Channels Activity Involved in the Memory Loss
Awards12:25 – 12:45 am

Lunch

12:45 pm (Box lunches will be available for take away.)

8

CaBP19 – Vanderbilt University

Directions from the airport to Terrace Place parking garage: Take I-40 West towards Nashville. Follow the signs for I-24
West/I-40 West, then I-65 South/I-40 West. Exit at Broadway. At the base of the ramp, go straight through the traffic light at
McGavock Street, and turn left onto Broadway. Stay right. Continue on Broadway to 16th Avenue, where the road splits. Veer
right onto West End Avenue. Turn left onto 21st Avenue South (a one-way street). Take the first left onto Terrace Place. Go
1/2 block. The Terrace Place garage entrance will be on your left.

9

CaBP19 – Vanderbilt University

Nashville taxi services (partial list):
Allied Cab – 615-333-3333
American Music City Cab – 615-865-4100
Green Cab – 615-424-6000
Magic Taxi – 615-500-5000
Nashvegas Cab – 615-332-3333
United Cab – 615-228-6969
Volunteer Cab – 615-955-7777
Shuttle services (reservations required):
In Shuttle – www.inshuttle.com
Jarmon Transportation – http://jarmontransportation.hudsonltd.net/res
Uber Nashvillehttps://www.uber.com/cities/nashville
For additional transportation options
https://www.flynashville.com/ground-transportation/Pages/default.aspx

10

CaBP19 – Vanderbilt University

NASHVILLE AREA EVENTS & ATTRACTIONSEVENTS
Nashville Sounds Baseball (Oakland Athletics Triple-A Minor League Baseball Team)May 30 vs Las Vegas (New York Mets Triple-A affiliate), 6:35 pm
May 31 vs Las Vegas, 2:05 pm
June 1 vs Las Vegas, 7:05 pm
June 2 vs Salt Lake City (Los Angeles Angels Triple-A affiliate), 7:05 pm
Rickey Smiley & Friends
Saturday, May 30, 2015
Ryman Auditorium
8:00 PM$62.50, $52
As a beloved comedian, television host, actor and top rated nationally syndicated radio personality; Smiley has become one of
the entertainment industry’s most celebrated performers. Through his brilliantly crafted career of bringing humor to themasses, Smiley has established himself as a potent pillar of talent with the capacity to reach a multitude of audiences. Smiley
is one of the few “clean” comics amongst the top tier of contemporary great comedians and has amassed a deeply loyal fanbase of enthusiasts who gravitate to his quick-witted delivery and captivating energy.
Beethoven’s Fifth
Sunday, May 31, 7:00 PM
Schermerhorn Symphony Center
1 Symphony Place
615-687-6400
Event Description
One night only! Giancarlo Guerrero and the Nashville Symphony perform one of the greatest pieces ever written: Beethoven’s
Fifth Symphony, an extraordinary journey from darkness to light that continues to inspire and amaze more than 200 years
after it was written. This all-Beethoven program also features two more works by the master: His uplifting Egmont Overture,and his moving Violin Concerto, featuring up-and-coming soloist Benjamin Beilman.
See more at: http://www.nashvillelifestyles.com/events/beethovens-fifth#sthash.2RMJJ1q1.dpuf
The Music of Led Zeppelin – Night 1
Tuesday, June 2 @ 7:30 PM. $79
Schermerhorn Symphony Center
1 Symphony Place
615-687-6400
Event Description
HCA/TriStar Health Legends of Music Series
Bridging the gap between rock ’n’ roll and classical music, the Nashville Symphony will blow you away with The Music of Led
Zeppelin. Amplified by a full rock band, creator Brent Havens will guest-conduct the orchestra as they capture Led Zeppelin’s
sheer blast and power, riff for riff, while churning out new musical colors. The two-plus-hour concert features 18 classic
Zeppelin tunes, including “Stairway to Heaven,” “Heartbreaker,” “Black Dog,” “Immigrant Song” and more. The January 2014
show sold out instantly.
7:30 p.m. Tuesday, June 2, 2015 , 7:30 p.m. Wednesday, June 3, 2015
See more at: http://www.nashvillelifestyles.com/events/the-music-of-led-zeppelin-nightone#sthash.ZrykvL6E.dpuf

11

CaBP19 – Vanderbilt University

NASHVILLE AREA EVENTS & ATTRACTIONSDOWNTOWN ATTRACTIONSCountry Music Hall of Fame
222 Fifth Avenue
615-416-2001
www.countrymusichalloffame.org
The Country Music Hall of Fame and Museum identifies and preserves the evolving history and traditions of country musicand educates its audiences. Functioning as a local history museum and as an international arts organization, the CMHOF
serves visiting and non-visiting fans, students, scholars, members of the music industry. Current exhibits: Dylan Cash and the
Nashville Cats, Alan Jackson: 25 Years of Keepin’ It Country and Luke Bryan & Dirt Road Diary.
Ryman Auditorium
116 5th Ave North
615-889-3060
www.ryman.com
If the hallowed walls of the Ryman Auditorium could talk, the remarkable story they would tell is unmatched in entertainment
history. Its construction is a tale of divine inspiration. In the 1880s, when prominent businessman and steamboat captainThomas G. Ryman found salvation in the words of fiery evangelist Reverend Sam Jones, he vowed to build a great tabernacle
that would project Rev. Jones’s voice clearly and powerfully for all to hear. Designed by architect Hugh Cathcart Thompson in
the Late Victorian Gothic Revival style popular at the time, Tom Ryman’s vision became a reality with the completion of theUnion Gospel Tabernacle in 1892. After his death in 1904, the Union Gospel Tabernacle would henceforth be known as the
Ryman Auditorium in honor of the man who built the Nashville landmark.
Wildhorse Saloon
Restaurant, bar, line dancing, entertainment
422 Broadway
Telephone: 615-726-0463
www.wildhorsesaloon.com
Home to exhilarating live entertainment and free line dancing, the Wildhorse Saloon is rooted deep in music traditions fromlocal acts to national artists. The Wildhorse Saloon opened in the heart of Music City near famous Music Row on historic
Second Avenue with the Cumberland River in our backyard. "Limited Engagement Acts" that played the Wildhorse Saloon
such as Darius Rucker, Etta James, 38 Special, Rick Springfield, Big & Rich, Ringo Starr and many more have all called theWildhorse Saloon home for a time. You never know who you will see here at the World Famous Wildhorse Saloon!
Tootsies Orchid Lounge
Honky-Tonk, Live Music
www.tootsies.net
Tootsie’s Orchid Lounge, a Nashville country music institution and world-famous honky-tonk, has operated across the alley
from the Ryman almost continuously since 1960. Its proprietor from 1960 to 1978, Hattie Louise “Tootsie” Bess, bought thelounge called “Mom’s” and named it for herself. According to tradition, a painter mistakenly painted the exterior orchid
purple. The color was never changed and became Tootsie’s signature color. Over the years, she served such famous
customers as Kris Kristofferson, Faron Young, and Willie Nelson when they were still up-and-coming artists, and Tootsie waswell-known for her generosity toward struggling musicians. The photo- and memorabilia-lined walls are called “Tootsie’s Wallof Fame.” A portion of the Loretta Lynn biopic “Coal Miner’s Daughter” was filmed inside Tootsie’s.

12

CaBP19 – Vanderbilt University

Riverfront Park
100 1st Ave N
Directly across First Avenue is Riverfront Park, created in the early 1980s to commemorate Nashville’s river history. In the
1780s, Nashville’s first settlers came both over land and via the river to settle here along the Cumberland River. Those settlers
built a two-acre fort around a freshwater spring and tucked among the cedar trees on the river bluff. A 1930 replica of thatfirst settlement, Fort Nashborough, stands north of Riverfront Park in Bicentennial Park. Also located in Bicentennial Park is
Alan LeQuire’s statue of Timothy Demonbreun, an early French Canadian fur trader who settled here, and Puryear Mims’s
sculpture of town founders James Robertson and John Donelson. Across the river, but highly visible from Broadway, sits Alice
Aycock’s monumental sculpture, Ghost Ballet for the East Bank Machineworks, installed in 2007. The artist’s concept
combined elements from the industrial heritage of the east bank as well as the modern driving energy of today’s city, andsymbolically connects the east bank to the west, unifying the city. *Reconstruction of Fort Nashborough is in process: creating
a modern interpretation of the frontier settlement.
Shelby Street Pedestrian Bridge
Shelby Street Pedestrian Bridge spans the Cumberland River and connects downtown's popular 2nd Avenue area to LP Field.
It's a local favorite for photography and river views, a romantic stroll, or a special event. The bridge spans 3,150 feet, one of
the longest pedestrian bridges in the world. On each side of the bicycle lane are 10-foot-wide elevated boardwalk-stylesidewalks. The bridge includes four scenic pedestrian overlooks that, in the metal of the railing, have artistic renderings of thehistory of life on the Cumberland River. The bridge is dramatically lit at night. The refurbished bridge is part of the Metro
Nashville Greenway system. The eastern terminus includes a pedestrian plaza with special landscaping and is very close to LP
Field. The western terminus comes out facing the Schermerhorn Symphony Center, close to the Country Music Hall of Fame.

13

CaBP19 – Vanderbilt University

NOTES

14