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2005 English: Contact pages "other text",p HDTV Series Torrent Snatch Rar.Heart transplantation in paediatric patients withdilated cardiomyopathy: indications and results at the Medical University of Vienna, Austria. Allo- and autotransplantation ofthe heart are now accepted as standard treatment for end stage dilated cardiomyopathy in adults, but are still consideredexperimental and discouraged for children. Since 2006, we have performed heart transplantation in four children with dilated
cardiomyopathy (three of them hypertrophic) and chronic heart failure. All recipients were treated with heart failure therapy
and immunosuppression after transplantation (tacrolimus monotherapy). One recipient received a ventricular assist device(VAD) as a bridge to transplantation until stable transplant function. During transplantation, no donor and three recipient deaths
occurred in association with heart decompensation, graft failure, and sepsis. An eight-month-old boy remained well until death
after VAD implantation. Another four-year-old boy remains well, despite acute rejection of his transplant at day fifty posttransplant. The third patient died of sepsis two years post-transplant. The fourth patient is alive, but receiving heart failure
medication. Heart transplantation in paediatric patients with end stage dilated cardiomyopathy is associated with a highmortality in the early post-transplant period. Chronic heart failure therapy and immunosuppression must be optimized to prevent
infection and rejection as the primary risk factors. Heart transplantation may be indicated in selected children when heart
failure therapy has not been successful despite medical treatment.During this period, the NCGC has worked to identify smallmolecule hits to address various primary goals in this proposal. As a center, the NCGC has fostered and maintained over 110
active collaborations with both NIH and extramural investigators, facilitating drug discovery efforts across the entire spectrumof human disease. These efforts have led to dozens of high-throughput screens and a number of medicinal chemistry campaigns
to further improve on screening hits, providing our collaborators and the general research community with publications and avariety of promising small-molecule probes and leads. In

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Contpaq 2005 Full Taringa REPACK