KOK E N COS M E TIC R AW MATERIALSStand by life, stay next to beauty
Since the foundation in 1959, we have developed products based on
research on macromolecules for medical use in accordance with thestatement by Founder Taichiro Akiyama,“valuing originality and providing the products and services leading to people's well-being.”｠
Having done research and development on artiﬁcial skin based on
medical grade silicone, we focus on highly biocompatible collagen as a
new macromolecule material. We successfully established methods for
manufacturing Atelocollagen, collagen with higher solubility and safety,
while maintaining the innate triple-helix structure and achieved the ﬁrst
application to cosmetic products in Japan.
｠As the world’s leading Atelocollagen manufacturer, we are constantly
evolving by performing cutting-edge research on regenerative medicine,
drug carriers and other areas.
｠With the technological capacities cultivated on the medical front, where
precision is required, we develop and provide our original and genuine
cosmetic raw materials based on the power of natural products.

02

The history of Koken as a cosmetic raw material manufacturer has
followed collagen and its evolution will continue.

Over 5,000 years ago

People used glue, a natural adhesive mainly based on gelatin,
produced by boiling animal skin and bone in water.
In the word collagen,“coll”means glue, and“gen”means source. Thissuggests that people became aware of collagen when they started touse glue.

1700s

The industrial production of gelatin commenced in Europe.

1930s

Researchers advance analysis of collagen structure.
Researchers clarify that collagen consists of polypeptides, made of about
1,000 amino acids, and is an elongated molecule with a triple-helix structure, comprising three polypeptide chains.

1930s

Industrial use of peptide collagen

1960sTechnology established for mass production of Atelocollagen
Collagen with telopeptides removed through enzyme treatment named
Atelocollagen in 1974. The name consists of t wo Latin words,“a”and“telo.”The former means removal, and the latter means end.

1978

Koken Atelocollagen, launched the ﬁrst Domestically produced
collagen for cosmetic use.
At that time, some cosmetic products used German collagen, which was
ex tracted using the acid solubilization process. It was unsuitable forcosmetic use because telopeptides with antigenicity were left untreated,causing turbidity. Therefore, Atelocollagen became popular in Japan.

1979

Koken Atelocollagen SS was launched as modiﬁed
Atelocollagen with increased solubility.

1986

Collagen for subcutaneous injection (Atelocollagen) launched.
Since then, Koken has marketed medical devices based on Atelocollagenfor medical use, such as hemostatic agents, dental bone prosthetic materials, and materials for treating dry eye.

1991

Freeze-dryers introduced for mass production.
The full-scale commencement of the OEM business forfreeze-dried (FD) cosmetics.

2012

Manufacturing line for FD cosmetics expanded
in Sakata, Yamagata.
The facilities are the largest scale in Japan.

Today

Dissemination of Atelocollagen.
Cosmetics ﬁeld

：Raw materials of collagen are distributed, having
added value in terms of molecular weight, source
and function.
FD business：Production has continued for over 30 years.
Advanced research：Research on Atelocollagen as a base material forregenerative medicine or a drug delivery carrier.

03

COLLAGEN

NATURAL
MACROMOLECULE

BOTANICALFREEZE DRY

04

Four key factors in the Koken cosmetics business
Cosmetic raw materials and freeze-drying business

COLLAGEN
Koken is the world’s leading company in the ﬁeld of
triple-helix-structured Atelocollagen that is the closest to human skin.

It is pursuing genuine beautiﬁcation for the sake of skin healthas a pioneer in the application of collagen to cosmetics.

NATURAL MACROMOLECULE
Koken meets a variety of needs, such as functionality, natural basematerials, and environmental friendliness, using domestically produced,
plant-based polysaccharides that are unique and sustainable.
It extracts elastin, the ingredient for ﬁrmness and elasticity that support
collagen in the skin and applies it to cosmetic materials. The lineup
also includes ﬁsh-derived products.

BOTANICAL
Domestically produced, plant-based raw materials. Koken develops
safe and reliable plant-based raw materials with clear traceability,
taking into account the usefulness of these materials made in Japan,
including Yamagata, where the company’s production is based.
It makes sustainable eﬀorts with local producers, such as using
recycled resources.

FREEZE DRY
Koken oﬀers freeze-dried collagen materials in pursuit of the innate
power of the perception of collagen.

It oﬀers OEM -related services for diﬀerentiation with high quality
and value added, making the most use of ingredient functions.

05

PRO D U C TS S ELEC TIO N

Choose by function/concept
page

Moisturizing

Firmness andelasticity

Prevention of
wrinkles andsagging

Brightening andradiance

Film forming andhigher barrier
function

Antiaging(antioxidation)

11

Collagen products

15

Pholitect®

15

Sacran15

Elastin17

Cherry Koken

17

LaFrance Koken

17

Melon Koken

17

Suika(Watermelon) Extract
Obanazawa

18

Rice Extract Koken

18

SHONAI BIJIN-RiceFermented Extract(SAKE)

18

Squeezed Rice Oil

11

Collagen products

11

Soluge15

Elastin11

Collagen products

11

Soluge15

Elastin18

LaFrance Powder Koken

22

Aqua gel

18

SHONAI BIJIN-RiceFermented Extract(SAKE)

18

Squeezed Rice Oil®

11

Collagen products

15

Pholitect®

15

Sacran ®

18

Squeezed Rice Oil

17

Cherry Koken

17

LaFrance Koken

17

Suika(Watermelon)
Extract Obanazawa

17

Cherry Powder Koken

18

LaFrance Powder Koken

18

Shonai Kaki Powder Koken

18

Squeezed Rice Oil

Antiaging(antiglycation)

17

Suika(Watermelon)
Extract Obanazawa

Anti-inﬂammation

15

Pholitect®

15

Sacran ®

17

Suika(Watermelon)
Extract Obanazawa

17

Cherry Powder Koken

Irritation alleviation 11
15
06

page

Shark Fin Atelocollagen Products
Pholitect®

Cell proliferation,
cell activation,and promotion of
turnover17

LaFrance Koken

17

Melon Koken

17

Suika(Watermelon) Extract
Obanazawa

18

Shonai Kaki Powder Koken

Promotion of
NMF production

17

Cherry Koken

17

Suika(Watermelon) Extract
Obanazawa

Improvement ofskin quality andchapped skin17

Cherry Koken

17

Melon Koken

17

Suika(Watermelon) Extract
Obanazawa

Skin conditioning

18

Rice Extract Koken

18

SHONAI BIJIN-RiceFermented Extract(SAKE)

Promotion ofblood circulation

18

Rice Extract Koken

18

SHONAI BIJIN-RiceFermented Extract(SAKE)

Peeling

17

Cherry Koken

18

Rice Extract Koken

18

SHONAI BIJIN-RiceFermented Extract(SAKE)

17

Cherry Powder Koken

18

LaFrance Powder Koken

18

Shonai Kaki Powder

Improvement of
texture15

Pholitect®

Improvement of
foaming property
and stabilizationof emulsiﬁcation

11

Shark Fin Atelocollagen MS

11

Porcine Atelocollagen MS

15

Pholitect®

Deodorization

18

Shonai Kaki Powder Koken

Hair care

11

Soluge18

Squeezed Rice Oil

Scalp care

17

Suika(Watermelon)
Extract Obanazawa

Makeup15

Pholitect®

Countermeasures
to UV rays andphotoaging

15

Pholitect®

18

Squeezed Rice Oil

Soft skin scrubCategorized list
Category

INCI nameProduct name

Correspondence

Collagen

ATELOCOLLAGEN

Soluge

中文名称

Sustainable

Domestically
produced

SOLUBLE COLLAGEN

Shark Fin Atelocollagen

中文名称

Sustainable

Domestically
produced

Tilapia Atelocollagen
Porcine Atelocollagen
Porcine Atelocollagen
SUCCINOYL

Shark Fin Atelocollagen SS

ATELOCOLLAGEN

Shark Fin Atelocollagen SS-V

Sustainable

Shark Atelocollagen SS
Porcine Atelocollagen SS
Porcine Atelocollagen SS-V

中文名称

ATELOCOLLAGEN

Porcine Atelocollagen MS

中文名称

HYDROLYZED ELASTIN

Elasocean

中文名称

Sustainable

SUCCINOYLElastinHydrolyzed α-Elastin
Hydrolyzed Elastin
Polysaccharides

Botanical
extract

Fermented
extract

Oil

11
11
11
11

Domestically
produced

11
11
11
11

Domestically
produced

11

Domestically
produced

1115

Sustainable

15

中文名称

15

PHOLIOTA MICROSPORAPOLYSACCHARIDES

Pholitect®

中文名称

Sustainable

Domestically
produced

Pesticide-free

15

APHANOTHECE SACRUM
POLYSACCHARIDES

Sacran ®

中文名称

Sustainable

Domestically
produced

Pesticide-free

15

PYRUS COMMUNIS(PEAR)
TWIG EXTRACT

LaFrance Koken PE

Sustainable

Domestically
produced

17

PRUNUS AVIUM(SWEET CHERRY)FRUIT EXTRACT

Cherry Koken

中文名称

Sustainable

Domestically
produced

17

CUCUMIS MELO(MELON)FRUIT EXTRACT

Melon Koken

中文名称

Sustainable

Domestically
produced

Picked
young

17

中文名称

Sustainable

Domestically
produced

Pickedyoung

17

Suika(Watermelon) Extract
CITRULLUS LANATUS(WATERMELON) FRUIT EXTRACT Obanazawa
Powder11

Domestically
produced

中文名称

Shark Fin Atelocollagen MS

MYRISTOYL

11

Domestically
produced

中文名称

中文名称

page

PRUNUS AVIUM(SWEET CHERRY) FRUIT

Cherry Powder Koken

Sustainable

Domestically
produced

17

PYRUS COMMUNIS(PEAR)FRUIT

LaFrance Powder Koken

Sustainable

Domestically
produced

18

DIOSPYROS KAKI FRUITPOWDER

Shonai Kaki Powder koken

Sustainable

Domestically
produced

18

RICE FERMENT FILTRATE(SAKE)ORYZA SATIVA(RICE) BRAN OIL

Rice Extract Koken MPN

中文名称

Sustainable

Domestically
produced

18

Rice Extract Koken BG

中文名称

Sustainable

Domestically
produced

18

SHONAI BIJIN-RiceFermented Extract(SAKE)

中文名称

Sustainable

Domestically
produced

18

Squeezed Rice Oil

中文名称

Sustainable

Domestically
produced

1807

COLLAGEN
Collagen is the main component of the dermis
and bones of animals. At Koken we manufacture Atelocollagen with high biological compatibility through enzyme treatment of collagen.
We oﬀer Atelocollagen that is strengthened interms of compatibilit y with other cosmetic
ingredients, lipophilicity, and permeability inthe skin through special processing, including
alkali treatment and chemical modiﬁcation.
Our product lineup contains a variety of Atelocollagen from diﬀerent sources, such as shark,
tilapia, porcine, and bovine to be ready for awide range of cosmetic products.

08

COLLAGEN

What is collagen?
Collagen accounts for approximately 25% of all proteins in the body and at least 70% of the dermal layer as the main
component. It is present in skin, bones, teeth, corneas, blood vessels, and tendons. Approximately twenty-nine typesof collagen exist. In human skin, collagen can be found in the dermis and the basal membrane, functioning as a foundation for the skin and maintaining ﬁrmness, elasticity, and water. If the amount or quality of collagen declines, forinstance, breaking and adverse cross-linking, then it may cause wrinkles, less elasticity, or sagging in the skin.
Collagen accounts for about 70% of the dermal layer.
About 300 nm
About 1.5 nm

Polypeptide comprising about 1,000 amino acids

Gly

In the dermis, collagen
exists as elongated proteinwith a triple-helix structure
and a molecular weight ofabout 300,000

X

Y

Gly

X

Y

Gly

X

A polypeptide chain consistsof a repeated amino acid sequence speciﬁc to collagen(Gly-X-Y).

Y

Collagen is rich in proline and hydroxyproline, which featureshigher water-retaining capacity than other amino acids. It isalso characterized by its high hydrophilic property. Hydroxyproline is a special amino acid that plays an important role inmaintaining the triple-helix structure, only found in collagen.

Eﬀects of collagen on the skin
Collagen is a macromolecular protein, containing a large quantity of water-retaining amino acids, with a molecularweight of 300,000. Therefore, collagen prevents the evaporation of water from the skin and excels in moisturizing eﬀect.
There are the hydrosoluble collagens that maintain the innate triple-helix structure of the skin (Atelocollagen), Succinoyl
Atelocollagen that is manufactured by chemically modifying Atelocollagen to increase the water-retaining capacity, andMyristoyl Succinoyl Atelocollagen with a high aﬃnity to the skin. On the other hand, middle size collagen has a diﬀerent
molecular size and materializes both the high moisturizing capacity and activation of cellular functions. It is expected to
upgrade ﬁrmness and elasticity from inside the skin, such as stimulating the synthesis of collagen and elastin.
Variety
Skin barrier andhighly moisturizing
type
Basic type

Succinoyl Atelocollagen
Myristoyl Succinoyl Atelocollagen
Soluble Collagen

Protects the skin from external stimuli. Fills the horny layer with waterthat boasts good affinity to the skin.

Water- Penetraretainingtion
capacity power

High

Low

Low

High

Approx. 300,000

Balancing typeMiddle CollagenM oisturizes both the insideand outside of the skin andactivates cellular functions.

Approx.
10,000 to
100,000

Penetrating typeHydrolyzed Collagen

Penetrates through the horny
layer to deliver water.

Approx.
Hundreds tothousands

Barrier function of Atelocollagen

110

100

Hydrolyzed
CollagenMiddleCollagen

4,000

10,000 to
100,000

Atelocollagen(Soluble
Collagen)Succinoyl
Atelocollagen

300,000

Myristoyl
Succinoyl
Atelocollagen

Barrier function

93.6

100

Living cell count (%)

Water-retaining capacity

120

105

95

Molecular weightHas a high water-retaining
capacity and retains water.

Atelocollagen

Water-retaining capacity
Water retaining rate in ﬁve minutes (%)

Characteristic

98.6
78.5

80
60

41.3

40
20

14.3

0

0.005% 0.05%

Not added

0.005% 0.05%

Atelocollagen
Succinoyl(Soluble Collagen) Atelocollagen0.005% 0.05%

0.05%

Myristoyl Succinoyl
Atelocollagen

Hydrolyzed
CollagenThe cell survival rate was assessed after diﬀerent varieties of collagen were applied
to cells, and an external stimulus was given with sodium dodecyl sulfate (SDS).
Atelocollagen products showed a higher barrier eﬀect than hydrolyzed collagen.
Above all, Succinoyl Atelocollagen exhibited the highest barrier function.

09

Varieties of collagen
Koken provides nondenatured macromolecular collagen with an innate triple-helix structure. Our collagen products
are processed at a low temperature and are sophisticatedly reﬁned throughout the process from extraction to
reﬁnement. That is why our products are odorless. In particular, the technology for removing non-helical regions fromcollagen consists of extraction methods that are employed in the manufacturing of collagens for medical use. The
technology permits Atelocollagen with high biological compatibility that is produced by removing telopeptides
attributable to allergy.
Gelatin

Collagen peptide

Raw material (skin etc.)

Characteristics of collagens from Koken
HighpurityTriple-helix structure
N-TelopeptideHighmolecule

C-Telopeptide

Highmoisturizing
property

Site attributable to allergy

Enyme extraction

Acid extracted collagen

Atelocollagen

Alkari extraction
Alkali extracted collagen

NH2

CONH2

NH2

CONH2

NH2

COOH

COOH

NH2

COOH

NH2

COOH

NH2

Atelocollagen
Modiﬁcation(Succinylation)

Atelocollagen H

Modiﬁcation(Myristoylation・Succinylation)

CO CH2 COOH

CO CH2 CH2 COOH

NH

CONH2

NH

CONH2

COOH

NH

COOH

12 CH3NH CO （CH2）

Water-retaining amount in 1.0 g of samples
Relative value with the water retention ofhydrolyzed collagen set to 1

Acid extraction

Middlization

14
12
10

About 13 times
higher8
6
4
20

Hydrolyzed
CollagenGelatinAtelocollagen

CO CH2 CH2 COOH

Atelocollagen SS

Atelocollagen MS

SolugeThicking agent added

Atelocollagen SS-V
＊Isoelectric point: pH that becomes cloudy

Product name

INCI name

Isoelectric
point＊(pl)

AcidicNeutralAlkaline

Compatibility
with otheringredients

Physical properties

Atelocollagen

SOLUBLE COLLAGEN

9.1

●

×

×

＋

Basic type

Atelocollagen SS

SUCCINOYL ATELOCOLLAGEN

4.5

△

●

●

＋＋

Collagen that is made by modifying succinicacids to increase compatibility

Atelocollagen SS-V

SUCCINOYL ATELOCOLLAGENCELLULOSE GUM

4.5

△

●

●

＋＋

Highly stable collagen that prevents decreased
viscosity caused by heat

Atelocolalgen MS

MYRISTOYL SUCCINOYL ATELOCOLLAGEN

4.5

△

●

●

＋＋＋

Amphiphilic collagen with succinic acids andmyristic acids modiﬁed

Atelocollagen H

SOLUBLE COLLAGEN

5.1

△

●

●

＋＋

Soluble collagen that is easy to dissolve
under neutrality conditions

SolugeATELOCOLLAGEN

9.5

●

●

△

＋＋＋＋

Middle-sized Atelocollagen with increased
solubility and compatibility： Hydrogen ion concentration
for dissolution

Hydrogen ion concentration for dissolution of various collagens

Amphiphilicity of Atelocollagen MS

Atelocollagen
Atelocollagen SS
Atelocollagen MS
Atelocollagen

Atelocollagen H
Soluge
2

10

3

4

5

6

7

8

9

10

11

12

Atelocollagen MS

Appearance was observed after 10 g of 0.1%
collagen solution was added to 0.1 g foam-type
face wash. Vials were shaken 100 times andleft for ﬁve minutes.

COLLAGEN

PRO D U C TS LI N EU P Collagen
Shark Fin Atelocollagen

Product number

Rare, domestically produced baby-skin-like collagen. This is natural marine Atelocollagen that
contains a 50% baby- collagen-like substance(homotrimer collagen: elastoidin).

AFN-221 ・ AFS-121 ～ 221 ・ AFV-121 ・ AFM-521
Domestically produced material
Marine derived

Moisturizing

Sustainable
Firmness and elasticity
Barrier function

Prevention of wrinkles and sagging
Film formation

Irritation alleviation

Stabilization of emulsiﬁcation

Improved foaming property■ Source: shark (ﬁn) ■ Origin: Kesennuma, Miyagi ■ Main Ingredients INCI name: ①SOLUBLE COLLAGEN②SUCCINOYL ATELOCOLLAGEN ③MYRISTOYL SUCCINOYL ATELOCOLLAGEN

SolugeProduct number

Technology for removing non-helical regions fromcollagen to manufacture collagen for medical use
and the industry’s ﬁrst middle size collagen. The

AFN-221
Domestically produced material
Marine derived

Moisturizing

Sustainable
Firmness and elasticity

Prevention of wrinkles and sagging

Hair caresizing process achieved both high moisturizing
capacity and activation of cellular functions at thesame time. It is characterized by high compatibility with other ingredients, high solubility, and easeof formulation.
■ Source: shark (skin) ■ Origin: Kesennuma, Miyagi ■ Main Ingredient INCI name： ATELOCOLLAGEN

Shark Atelocollagen

Product number

N atu ral ma rin e coll a gen ex trac te d fro m th edermis of blue shark harvested in Kesennuma,

ASS-121 ～ 221
Sustainable

Domestically produced material
Marine product based

Moisturizing

Firmness and elasticity

Miyagi. It is characterized by a less viscous feel

Prevention of wrinkles and sagging

Barrier function

than animal-based collagen. It easily penetrates

Film formation

the skin and feels like adhesive.
■ Source: shark (skin) ■ Origin: Kesennuma, Miyagi ■ Main Ingredient INCI name： SUCCINOYL ATELOCOLLAGEN

Tilapia Atelocollagen H

Product number

Natural ﬁsh Atelocollagen extracted from tilapia

ATH-121 ～ 221
Fish-derived

Sustainable

scales. It has higher thermal stability than otherFirmness and elasticity

ﬁsh-derived collagens because it is highly soluble

Barrier function

Moisturizing

Prevention of wrinkles and sagging

Film formationin neutral solutions and made from tropical ﬁsh.

■ Source: Tilapia (scale) ■ Origin: Taiwan ■ Main Ingredient INCI name: SOLUBLE COLLAGEN

Porcine Atelocollagen

Product number

Collagen extracted form porcine dermis. As a por-APN-211 ～ 221 ・ APS-111 ～ 411 ・ APV-121 ～ 623
Domestically produced materialcine-derived raw material, we use the dermis ofFirmness and elasticity

d o mestically farme d , healthy pig s that have

Barrier function

passed inspection under Article 10 of the Slaugh-

Improved foaming property

Moisturizing

Prevention of wrinkles and sagging

Film formation

Stability of emulsiﬁcation

te rh o u s e Ac t . T h e raw m ate ria l is clos e r tohumans in the amino acid comp osition thanﬁsh-derived collagen. It is highly stable.
■ Source: porcine (skin) ■ Origin: Japan ■ Main Ingredients INCI name: ①SOLUBLE COLLAGEN②SUCCINOYL ATELOCOLLAGEN ③MYRISTOYL SUCCINOYL ATELOCOLLAGEN

11

S PEC I FIC ATI O N Collagen
Collagen (shark ﬁn)
Product number

Product name

AFN-221

Shark Fin Atelocollagen 1% PE

AFS-121

Shark Fin Atelocollagen SS 0.3%PE

AFS-221

Shark Fin Atelocollagen SS 1% PE

AFV-121

Shark Fin Atelocollagen SS-V 0.3% PE

AFM-521

Shark Fin Atelocollagen MS 0.8% PE

Main ingredient INCI NameSOLUBLE COLLAGENSUCCINOYLATELOCOLLAGEN

中文名称
可溶性胶原

琥珀酰缺端胶原

Other ingredients

Property Package

Citric acid, sodium citrate,
phenoxyethanol, water
Disodium phosphate,potassium phosphate,
phenoxyethanol,
water

Solution

1kg

Disodium phosphate, potassium
phosphate, phenoxyethanol,
cellulose gum, water
MYRISTOYL SUCCINOYLATELOCOLLAGEN

肉豆蔻酰琥珀酰/端胶原

Main ingredient INCI Name

中文名称

Disodium phosphate,potassium phosphate,
phenoxyethanol, water＊Methylparaben(MP) products are made-to-order.

Collagen (shark skin)
Product number

Product name

AFN-221

Soluge 1% PE

ASS-121

Shark Atelocollagen SS 0.3% PE

ASS-221

Shark Atelocolalgen SS 1% PE

Other ingredients

ATELOCOLLAGEN

缺端胶原

Phenoxyethanol, water

SUCCINOYLATELOCOLLAGEN

琥珀酰缺端胶原

Disodium phosphate,potassium phosphate,
phenoxyethanol, water

中文名称

Other ingredients

Property Package
1kg
Solution
1kg＊Methylparaben(MP) products are made-to-order.

Collagen (ﬁsh-derived)
Product number
ATH-121
ATH-221

Product nameMain ingredient INCI Name

Tilapia Atelocollagen H 0.3% PE
Tilapia Atelocollagen H 1% PE

SOLUBLE COLLAGEN

可溶性胶原

Disodium phosphate,potassium phosphate,
phenoxyethanol, water

Property Package

Solution

1kg

Collagen (porcine)
Product number
APN-211

Product nameMain ingredient INCI Name

Porcine Atelocollagen 1% MP
SOLUBLE COLLAGEN

可溶性胶原

Other ingredients

Citric acid, sodium citrate,
phenoxyethanol, water

Porcine Atelocollagen 1% PE

APS-111

Porcine Atelocollagen SS 0.3% MP

Disodium phosphate, potassium
phosphate, methylparaben, water

APS-121

Porcine Atelocollagen SS 0.3% PE

Disodium phosphate, potassium
phosphate, phenoxyethanol, water

APS-211

Porcine Atelocollagen SS 1% MP*

SUCCINOYLATELOCOLLAGEN

琥珀酰缺端胶原

APS-411

Porcine Atelocollagen SS 2% MP*

APV-121

Porcine Atelocollagen SS-V 0.3% PE

APV-623

Porcine Atelocollagen SS-V 0.05% PE

APM-211

Porcine Atelocollagen MS 1% MP

MYRISTOYL SUCCINOYLATELOCOLLAGEN

肉豆蔻酰琥珀酰/端胶原

APH-311

Porcine Atelocollagen H 1.5% MP

SOLUBLE COLLAGEN

可溶性胶原

Property Package

Citric acid, sodium citrate,methylparaben, water

APN-221

Disodium phosphate,potassium phosphate,methylparaben, water
Disodium phosphate,potassium phosphate,
phenoxyethanol,
cellulose gum, water＊Phenoxyethanol(PE) products and bovine Atelocollagen are made-to-order.

12

中文名称

Disodium phosphate,potassium phosphate,methylparaben, water

1kg

Solution

10kg

1kg

Importance of domestically produced materials
Koken identiﬁes the power of natural materials to draw new potential from them.
Our products are made from domestically produced materials
that are selected with consideration for safety and reliability.

Increased needs for natural
and/or domestically
produced materials

La France pears,
the Yamagata specialty,
triggered new development

Eco-friendly,
sustainable development of
raw materials

Today, more consumers want natural cosmetics made with the concept of naturally derived ingredients.
We have distributed the raw materials of cosmetics based on domestic a l l y p ro d u ce d m a te r i a l s a s a n
Atelocollagen pioneer and a specialist in macromolecular raw materials. With over 30 years of experience in the development of collagenfor cosmetic use and natural macromolecules, we have developed new
raw m a te ria l s t h a t s a t is f y m a ny
diﬀerent needs.
｠

Yamagata University and a local company i n Ya m a ga t a d is cove re d t h a t L aFrance pears contain β-arbutin andestablished the methods for extracting
and reﬁning the ingredient from branches of the fruit trees. Focusing on theusefulness, Koken developed LaFrance
Koken, a raw material for cosmetics, incooperation with the local company
and research institutes. In the past,
there were no extracts containing β- a rb utin d e rive d f ro m d o m estic ally
produced material s. This successful
development made us aware of new
potential for plant-based materials. It
triggered the commencement of raw
material development based on domestically produced, plant-based materials.

LaFrance Koken is an extract drawn
from branches that are agricultural
waste. It was developed as part of
the Yamagata 3Rs (Reduce, Reuse,
and Recycle) project for promoting
a recycling society. The cosmetic
products containing LaFrance Koken
aid recycling. We also develop otherraw mate rial s usi n g a g ri cu lt u ral
products that cannot be sold in the
consumer market due to their defective appearance and materials thata re h a rd l y u s e d a n d d i s c a rd e dbecause of limited use applications.

Pursuit of safety
and reliability
with clear traceability

Certain evidence
and pursuitof functionality

More potential
for domestically
produced materials

We esta blish e d a p ro d u c tio ns y s te m fe a t u ri n g t ra ce a b i l i t y i n
cooperation with the local governm e n t a n d t h e l o c a l co m p a ny i n
Yamagata, where our plant is located. Follow the production history,
i n clu d i n g t h e fa rm e rs . T his hi gh
traceability ensures product development that is safe and reliable for
consumers. We try to build a close
relationship with producers, local
agricultural cooperatives, the local
government, and local businesses,
and select materials strictly in material development.

To address consumers’skin con cerns, which is the main purpose ofcosmetics, we develop Japanese-made, functional raw materials supported by evidence as well as create
the image of safety and reliability. In
the long-term research and development with the local government, thel o c a l c o m p a n y, a n d t h e l o c a lresearch institutes (Yamagata Unive rsit y a n d Kei o U nive rsit y), we
discovered the usefulness of a wide
range of plants in Yamagata, thefruit kingdom prefecture, as materials for cosmetics, and use them as
new, raw materials.

We also use materials from otherareas. Atelocollagen is made froms h a r k h a r v e s te d i n Ke s e n n u m a ,Miyagi. Sacran is expected to be
used for healthcare, extracted from
Aphanothece sacrum, algae from
Ku m a m o to a n d Fu ku o ka . T h e s e
m a te ri a l s a re t h e re s u l t s o f t h eendeavors of producers and developers. To meet diverse cosmeticnee ds , we will d o research o n awide range of materials produced in
diﬀerent places of Japan and deliversafe, reliable, and original natural
raw materials.

13

NATURAL
MACROMOLECULE
Natural macromolecules extracted from plants,
marine creatures and other materials have functions speciﬁc to macromolecules that vary by raw
material, for instance, increase in viscosity, gelation, coating formation, stabilization of foam,moisturizing, and improvement in sense of use.
The product lineup includes plant-based Pholitect®
and Sacran®, and marine-creature-derived elastin.

14

NATURAL MACROMOLECULE

PRO D U C TS LI N EU P Natural macromolecule
Pholitect ®

Product number

PME-121 ・ PME-131

Botanical shield polymer was developed with a

Domestically produced material

focus on the high water-retaining capacity of poly-

Moisturizing

saccharides secreted by nameko mushrooms. It

Anti-inﬂammatory

alleviates external stimuli with high anti-inﬂamma-

Stabilization of emulsiﬁcation

tory and protective eﬀects.

Sustainable

Pesticide-free

Barrier function Skin protection Coating formation

MakeupIrritation alleviation

Improved texture

Improved foaming property

UV care■ Source:Nameko mushroom ■ Origin: Yamagata ■ Main ingredient INCI name: PHOLIOTA MICROSPORA POLYSACCHARIDES

Sacran ®

Product number

The macromolecular polysaccharide extracted from Aphanothece sacrum, with the molecular weight of approximately

29,000,000 Aphanothece sacrum is rare algae that is grownin the subsoil water from the Aso Mountains in Kyushu.

ーDomestically produced material

Sustainable

Pesticide-free

Moisturizing

Barrier function

Coating formation

Anti-inﬂammatory

Anti-pollution■ Source: Aphanothece sacrum ■ Origins: Kumamoto and Fukuoka ■ Main ingredient INCI name: APHANOTHECE SACRUM POLYSACCHARIDESElastin

Product number

EBA-211 ～ EME-221

The protein reinforces bonding between collagen to

Sustainable

make the skin ﬁrm and elastic. Decreasing with age,

Prevention of wrinkles and sagging

it is said to cause wrinkles and sagging in the skin.

Moisturizing＊

Firmness and elasticity＊Elasocean■ Main ingredient INCI name: HYDROLYZED ELASTIN
Product nameSourceExtraction method

Elasocean

Fish

Enzymatic extraction

Hydrolyzed Elastin

Bovine (nuchal ligament)

Enzymatic extraction

Hydrolyzed α-Elastin

Bovine (nuchal ligament)

Extraction using oxalic acid (low odor)

S PEC I FIC ATI O N Natural macromolecule
Pholitect ®
Product number

Product namePME-131

Pholitect BG

PME-121

Pholitect PE

Main ingredient INCI name

PHOLIOTA MICROSPORAPOLYSACCHARIDES

中文名称

Other ingredients

Naturally-derived index＊1 Property Package＊

Butylene glycol(plant-derived),
water

１

＊

Phenoxyethanol,
water

0.995

Solution

1kg＊The term“pholiota microspora polysaccharides”may be changed to“polyamino sugar condensate,”which is used by INCI. The Chinese term(中文名称) is 多氨基酸多糖縮合物.

Sacran ®
Product number

Product nameーSacran BーSacranMain ingredient INCI name

APHANOTHECE SACRUM
POLYSACCHARIDES

中文名称

水前寺紫菜
（APHANOTHECESACRUM）多糖

Other ingredients

Naturally-derived index Property Package

Butylene glycol,
water

0.7 ＊1

Solution

1kg

ー

１ ＊2

Fiber

10g

性状

包装

Solution

1kg

Elastin
Product number

Product nameMain ingredient INCI name

中文名称

Other ingredients

Naturally-derived index
0.996
0.993

EME-211

Elasocean 4% MP

Disodium phosphate, potassium
phosphate, methylparaben, water

EME-221

Elasocean 4% PE

Disodium phosphate,potassium phosphate,
phenoxyethanol, water

EBA-211

Hydrolyzed α-Elastin
4% MP＊

EBE-311

Hydrolyzed Elastin
10% MP＊HYDROLYZED ELASTIN

水解弹性蛋白Disodium phosphate,potassium phosphate,methylparaben, water

0.996
0.996

＊Phenoxyethanol(PE) products are made-to-order.
＊1: ISO 16128, mixing water included. ＊2: ISO 16128, mixing water not included. ＊Inquire about the naturally derived index for each raw material.

15

BOTANICAL
Domestically produced
plant-derived raw materials
Koken uses a variety of manufacturing methods,
such as extraction, freeze-drying, fermentation,and pressing, according to the characteristics ofthe materials and applies plant-based beauty
ingredients to cosmetic raw materials. The raw
materials have diﬀerent eﬀects, for example,
moisturizing, anti-aging, improvement of skinquality and chapped skin, prevention of sagging,and soft skin scrub.
The raw materials produced in Japan include La
France pears, cherries, melons, watermelons,Shonai Kaki persimmons, and rice.

16

BOTANICALPRO D U C TS LI N EU P Raw materials derived from domestically produced plants
Extract manufactured
by hot water extraction

Cherry Koken

Product number

CFE-131

The fruit extract is derived from cherries (Napo-

Domestically produced material

Sustainableleon). It is rich in polyphenol, with an anti-oxidant

Moisturizing

Anti-oxidant

eﬀect equivalent to vitamin C. It is an eco-friendly
raw material that uses inedible cherries from trees

Anti-aging

Promotion of NMF production

Improvement of skin quality

Peelingfor pollination.
■ Source: Cherries (fruit) ■ Origin: Yamagata ■ Main ingredient INCI name: PRUNUS AVIUM (SWEET CHERRY) FRUIT EXTRACT
Extract manufactured
by hot water extraction

LaFrance Koken

Product number

LWE-121 ・ LWE-131

The botanical extract is derived from the branch-

Domestically produced material

Sustainable

es of La France pear trees that are rich in natural

Moisturizing

Anti-aging

β-arbutin. It suppresses tyrosinase, inhibits mela-

Anti-oxidant

Beta-arbutin

Promotion of turnovernin production, and has an anti-oxidant eﬀect.
More eﬀective than synthesized arbutin, it is an
eco-friendly raw material and pruned branches,
which are industrial waste, are reused.
■ Source: La France pears (branch) ■ Origin: Yamagata■ Main ingredient INCI name: PYRUS COMMUNIS (PEAR) TWIG EXTRACT
Extract manufactured
by hot water extraction

Melon Koken

The fruit extract is derived from Wakazumi (young

Product number

MEE-131

Domestically produced material

picked) melons (Tsuruhime Red). Young picked

Picked young

melons contain more beauty ingredients than ripe

Improvement of skin quality

Moisturizing

Sustainable
Promotion of turnover

Texture and smoothness

fruits. They improve skin texture and smoothness.
To be eco-friendly, we use melons picked for fruit
thinning that used to be thrown away.
■ Source: Melon (fruit) ■ Origin: Yamagata ■ Main ingredient INCI name: CUCUMIS MELO(MELON) FRUIT EXTRACT

Suika(Watermelon) Extract Obanazawa

Extract manufactured
by hot water extraction

Product number

WME-131

The fruit extract is derived from Wakazumi (young

Domestically produced material

picked) watermelons (Obanazawa Watermelon).

Picked young

Moisturizing

Anti-aging

It addresses a variety of skin concerns, such as

Anti-oxidant

Anti-glycation

Anti-inﬂammation

Sustainabled u l l n es s , d is t u rb e d t u rn ove r, i n ﬂ a m m ati o n ,Promotion of turnover

Promotion of NMF production

decreased barrier func tion, and skin qualit yNatural moisturizing factor

Improvement of skin quality

issues, including texture, smoothness, and drying.

Peeling

Hair care

Sculp care

It promotes synthesizing hair growth genes. Recommended for sculpting or eyelash care. It is an
eco-friendly raw material that uses watermelons
picked for fruit thinning.
■ Source: Watermelon (fruit) ■ Origin: Yamagata■ Main ingredient INCI name: CITRULLUS LANATUS(WATERMELON) FRUIT EXTRACT

Cherry Powder Koken

Fruit powder(freeze-drying technique)

Product number

CFP-000

These powdered beaut y ingredients are con-Domestically produced material

tained in fruit and cherry juice (Beni Sayaka), man-Anti-aging

ufactured using a freeze-drying technique. Rich inSoft skin scrub

Anti-oxidant

SustainableAnti-inﬂammation

polyphenol and ﬂavonoid with potential anti-inﬂammatory and anti-oxidant eﬀects.
■ Source: Cherries (fruit) ■ Origin: Yamagata ■ Main ingredient INCI name: PRUNUS AVIUM(SWEET CHERRY) FRUIT

17

LaFrance Powder Koken

Fruit powder(freeze-drying technique)

Product number

LFP-000

These powdered beaut y ingredients are con-Domestically produced material

tained in La France fruit and juice, manufactured

Prevention of wrinkles and sagging

Anti-aging

using a freeze-drying technique. Potential beneﬁts

Anti-oxidant

Relaxation

Sustainable

Soft skin scrub

include prevention of skin sagging and an anti-oxidant eﬀect.
■ Source: La France pears (fruit) ■ Origin: Yamagata ■ Main ingredient INCI name: PYRUS COMMUNIS(PEAR) FRUIT

Shonai Kaki Powder Koken

Fruit powder(freeze-dried)

Product number

SKP-000

Powdered beauty ingredients contained in Shonai

Domestically produced material

Kaki fruits and juice produced in Yamagata are

Anti-aging

Anti-oxidant

manufactured with a freeze-drying technique. Rich

Soft skin scrub

Odor elimination

Sustainable
Promotion of turnoverin p o ly p h e n o l s , in clu din g c ate chin t hat ha santi-oxidant and deodorizing eﬀects, they havehigh cellular proliferation activit y to produce
anti-aging eﬀects.
■ Source: Persimmon fruit ■ Origin: Yamagata ■ Main ingredient INCI name: DIOSPYROS KAKI FRUIT POWDERRice Extract Koken

Fermented extract

Product number

RFF-111・RFF-121

The fermented extract of sake is made from rice

Domestically produced material

produced in Mie. Sake contains a variety of amino

Moisturizing

Sustainable

Improvement of barrier function

acids and organic acids, made using the power of

Natural moisturizing factor

Skin conditioning

fermentation of rice koji (malted rice) and yeast. It

Promotion of blood circulation

Dullnessis expected to condition the skin environment

Peeling

Radiance

Improvement of redness

similar to a sake bath.
■ Source: Rice plant ■ Origin: Mie ■ Main ingredient INCI name: RICE FERMENT FILTRATE (SAKE)SHONAI BIJIN-Rice Fermented Extract(SAKE)

Fermented extract

Product number

RFF-221

The rice fermented extract of Shonai Bijin, Jun-

Domestically produced material

Sustainablemai-shu is made from rice produced in Yamagata.

Media coverage accepted

Moisturizing

We employ the traditional Kimoto zukuri (brew-

Improvement of barrier functioning) method that fully utilizes the fermentation

D-amino acidpower of natural materials. Rich in amino acids,
peptides, glucose, and organic acids, it is expected to have moisturizing, peeling, skin-softening,

Natural moisturizing factor

Skin conditioning Promotion of blood circulation

Care for cold constitution and blood ﬂow
Dullness and stiﬀness

Peeling

Improvement of redness

Radiance

Suppression of sebum

and blood circulation promoting eﬀects.
■ Source: Rice plant ■ Origin: Yamagata ■ Main ingredient INCI name: RICE FERMENT FILTRATE (SAKE)

Squeezed Rice Oil

Functional oil

Product number

RBS-105

The plant-derived oil is pressed from the bran ofDomestically produced material

domestically grown rice and physically reﬁned

Moisturizing

Emollient

Barrier function

without chemicals. Contains γ-oryzanol, which

Brightening

Anti-aging

Anti-oxidationbrightens the skin and absorbs UV rays, andHair care

UV careSustainableanti-oxidants vitamin E and Super Vitamin E.
■ Source: Rice bran ■ Origin: Japan ■ Main ingredient INCI name:ORYZA SATIVA(RICE) BRAN OIL

18

BOTANICAL

SPEC I FIC ATI O N Raw materials derived from domestically produced plants
Botanical extract (hot water extraction)
Product number
CFE-131

LWE-131

Product name
Cherry Koken BG

Main ingredient INCI name
PRUNUS AVIUM(SWEET CHERRY)FRUIT EXTRACT

中文名称
欧洲甜樱桃
（PRUNUS AVIUM）
果提取物

Other ingredients

0.5
Butylene glycol, water
0.7

ー

LaFrance Koken BG

Naturally-derived index＊1 Property Package

PYRUS COMMMUNIS(PEAR)
TWIG EXTRACT
LWE-121

LaFrance Koken PE

MEE-131

Melon Koken BG

WME-131

Suika(Watermelon)
Extract Obanazawa
BGー

Phenoxyethanol, water

0.997

CUCUMIS MELO(MELON)FRUIT EXTRACT甜瓜（CUCUMIS MELO）
果提取物

Butylene glycol, water

0.7

CITRULLUS LANATUS(WATERMELON)FRUIT EXTRACT

西瓜（CITRULLUS LANATUS） Butylene glycol, water
果提取物

0.7

Solution

1kg＊We are able to receive special orders for products that do not contain water.

Fruit powder (freeze-drying technique)
Product number

Product nameMain ingredient INCI name

中文名称

Other ingredients

Naturally-derived index＊2 Property Package
1

CFP-000

Cherry Powder
Koken

PRURUS AVIUM(SWEET CHERRY) FRUITーMaltodextrin, sucrose,
Zea mays(corn) starch,Elaeis guineensis(palm) oil

LFP-000

LaFrance Powder
Koken

PYRUS COMMUNIS(PEAR)
FRUIT

ー

Cyclodextrin, sucrose,
Zea mays(corn) starch,Elaeis guineensis(palm) oil

1

SKP-000

Shonai Kaki Powder
Koken

DIOSPYROS KAKI FRUITPOWDERー

Maltodextrin, sucrose,
Zea mays(corn) starch,Elaeis guineensis(palm) oil

1

中文名称

Other ingredients

Powder100g

Fermented extract
Product number

Product name

RFF-111

Rice Extract Koken
MPN

RFF-121

Rice Extract Koken
BG

RFF-221Main ingredient INCI name

Sodium methylparaben

RICE FERMENT FILTRATE(SAKE)

稻米发酵产物滤液SHONAI BIJIN-RiceFermented Extract(SAKE) BG

Naturally-derived index＊1 Property Package
0.999

Solution
Butylene glycol(plant-derived)

1kg

１Functional oil
Product number

Product nameRBS-105

Squeezed Rice Oil

Main ingredient INCI name
ORYZA SATIVA(RICE)
BRAN OIL

中文名称

Other ingredients

稻（ORYZA SATIVA）
糠油ーNaturally-derived index＊2 Property Package
１

Solution 16.5kg＊1: ISO 16128, mixing water included: ＊2: ISO 16128, mixing water not included ＊Inquire about the naturally derived index for each raw material.

19

FREEZE DRY
Freeze-dried products
Koken commenced the consigned manufacturing of freeze-dried cosmetic products in 1991,
earlier than competitors in Japan, applying thefreeze-drying technique cultivated in the production of collagen for medical use.
We manufacture and sell freeze-dried products
and provide them as OEM, pursuing the innate
power of the perception of collagen.

20

FREEZE DRY

The research and development section and the production system
Koken has a research and development section and a production section at Tsuruoka Plant in Yamagata. A system
connects the research and development section that discusses formulation and the production section that engages
in consigned production. It allows us to develop products and carry out consigned business promptly according tocustomers’needs.
Sakata Plant was constructed as facilities specialized in the consigned freeze-drying business in 2012. It allows us toreduce lead time and oﬀer great ﬂexibility in lot sizes from small to large. Taking advantage of the industry’s largest
freeze-dryer, we concentrate on primary processing of raw materials (mass-production accepted) in addition to
OEM business for freeze-dried cosmetics.
Having introduced the quality management system compliant with ISO 9001 and arranged a superb quality control environment, we pursue high added value and quality of raw materials and cosmetic products using a freeze-drying technique.

Sakata Plant in Yamagata (automated plant specialized
in the OEM business using a freeze-drying technique)

Tsuruoka Plant in Yamagata

Strengths of Koken
High-quality product proposals
Products are expected to have higher restorability and dissolubility at
re-dissolution if they are processed into a spongy porous form. Our facilities permit replacement of air with nitrogen inside and automatic cappingof bottles, preventing oxidation. Based on 30 years of success, we will
support your business from planning and proposals to formula design.
Support to planning and formulation● We will propose formulas suitable for freeze-dried cosmetics containing
the requested ingredients.
● We are ready to design formulas containing a high concentration of collagen based on the advantages of a collagen manufacturer.
● Our support covers proposals of containers suitable for freeze-driedproducts, containers with a proven track record, and commercializationof products using containers that meet customer needs.
● We welcome requests or inquiries about primary processing for massproduction of cosmetics and novel formulas in addition to bottling.
Consignment business ﬂow

STEP 1

STEP 2

STEP 3

STEP 4

STEP 5

Planning

Formula design
and presentationof prototypes

Determinationof speciﬁcations
and quotation

Consignment
agreement andorder placement

Production
and delivery

We will make full use ofabundant knowledge thathas been cultivated over
30 years in production.

We will present a quotation after speciﬁcations are determined.

Legally valid contracts
a n d /o r a g re e m e n t s
will be concluded, andwe will receive orders.

We propose formulas
i n a cco rd a n ce w i t hrequests based on our
experience with many
diﬀerent products.

We will deliver products conforming to thequalit y standards tothe speciﬁed address
within Japan.

21

Freeze-dried raw materials
Aqua Gel
Aqua Gel is available as a soluble sheet or cube. It is dissolved in waterand turns into gel. It contains naturally derived ingredients such as alginic
acids, soluble collagen, and squalene. The freeze-drying technique allows
triple-helix collagen (raw collagen) to be kept in a fresh state. Preservative-free, the lightness adds convenience to products. Easily carry a product when travelling or going out.
＊An anti-wrinkle functionality test has been conducted on Koken Perfect Aqua Gel Sheet
Sold separately as packaging for aqua gel sheet(bulk) and cubic.
Preservative-freeFreeze-drying

Product number

Triple-helix collagen

Product nameATP7205

Koken Perfect Aqua Gel Sheet 2pcs/set

ATP7405

Koken Perfect Aqua Gel Sheet 4pcs/set

Moisturizing

Package

Anti-wrinkle

Ingredients (INCI name)50sets/box－

Koken Perfect Aqua Gel Sheet 2pcs/set(bulk)－

Koken Perfect Aqua Gel Sheet 4pcs/set(bulk)＊without alminium package

100sets/bag＊without alminium package

Cubic Koken Aqua Gel

475pcs/bottle－

Aluminum ﬂat bag with a notch (100×120 mm)

100sets/bag－

80-pack container for KPAGS (20×20 mm)

80pcs/bag

CTP9901

Property/Package

・ALGIN・PROPYLENE GLYCOL
ALGINATE
・SOLUBLE COLLAGEN・SQUALANE
・POLYGLYCERYL-10
LAURATE

Sold separately as packaging for aqua gel sheet(bulk) and cubicSpecial orders to be accepted (ingredients and shapes)

Aqua Gel Sheet

Cubic

Size:
20(L) x 20(W)x 1(H) mm
Weight: 8 ～ 9mg

Size: 8(L) x 8(W) mm
Weight: 10mg

Add ingredients freely and/or customize baseformulas. For sheet types, we are able to accept
special orders, such as for the eye area, roundshapes, and heart shapes.

What is freeze-drying?
Freeze-drying is the technique for manufacturing dried products by evaporating water from raw materials under a low temperature while they arefrozen. It is widely used, from food processing to medical device processing. The low-temperature processing permits stable storage of thermallyunstable raw materials. Freshness can be maintained because resulting
products lack moisture that can cause bacterial growth.

22FREEZE DRY

Freeze-dried cosmetics OEM business (cosmetic products)
We undertake the consigned FD processing business for double-form cosmetics that are prepared before use and re - melted when using by
freeze-drying these cosmetics as lotions and serums containing collagen
and/or raw materials with inferior temporal stability.
Examples of ingredients:
Triple-helix collagens, vitamins, and growth factors (GFs)

Production process

Manufacturing products in a clean environment, we oﬀer great ﬂexibility in lot sizes from small to large.

Prepare solution/Fil containers

Freeze-drying

Labeling/Testing

Shipment

OEM business for mass production (primary processing of raw materials)
We undertake the consigned FD processing business for raw materials
that require drying without heating. We will ﬁll trays with solution,
freeze-dry it, and deliver a large quantity of each product.
Examples of consigned businesses (including prototypes):
Surfactants, polysaccharides, and vitamin C derivatives＊We do not accept consigned powder processing.

Advantages of freeze-dried cosmetics
1 Makes full use of functions of beauty ingredients

2 No preservatives needed

The functions of ingredients can be maintained byremoving moisture and replacing the air with nitrogen for ingredients vulnerable to heat (collagen andgrowth factors) and ingredients that are easily oxidized and have low temporal stability (vitamin C).
Beauty ingredients can be delivered to the skin as
the most eﬀective condition is maintained if cosmetic products remain fresh until use.

The use of preservatives can be suppressed because
freeze-dried cosmetics do not contain water associated with bacterial proliferation. Freshness can be
maintained until products are used. Design cosmetic
products that only contain beauty ingredients whileremoving ingredients that add stress to the skin.

3 Concept of special care
Design formulas based on the concept of intensive
care because freeze-dried cosmetics can contain ahigh concentration of raw materials that are diﬃcult to
use in general serums that are less stable and include
water. Dissolve a product before use to feel the freshness and have a special feeling about the product.

23

＊The catalog is prepared based on the materials andexperimental data available as of the time of writing.
Please note that the contents of this catalogue do
not represent any warranty. ＊Note that details of
this catalogue are subject to change. Copyrights,
design rights, and any other intellectual property
rights in connection with the data given here andrelated documents are vested in Koken Co., Ltd., andthe company prohibits duplication, reproduction, andquotation of these details without permission. For
safe use of these materials, refer to the MSDS of the
product in advance. In addition, care should be taken
to comply with regulation in each country on expressions concerning consumer products.

Contact

KOKEN CO., LTD.
1-4-14 Koraku, Bunkyo-ku, Tokyo
112-0004 Japan
E-mail: customer@kokenmpc.co.jp
www.kokenmpc.co.jp

https://koken-cosme.com/Ⓒ2006-2021 KOKEN CO., LTD. C-1-704-1-04-00

2021.1