PROGRAM
August 28 (Tue.)

Room A

Opening and Award Ceremony (16:00-18:30)
General Chairperson: Satoshi Kokura, Secretary General

Opening Remarks

16:00-16:05

Toshikazu Yoshikawa, Kyoto Pref. Univ. of Med.

Keynote Lecture

16:05-16:30
Chairperson: Toshikazu Yoshikawa, President of ICHO2012KL

Hyperthermia & chemotherapy; from sarcoma to pancreatic cancer - a path for mainline oftumor treatment?
Rolf D. Issels
Med. Clinic III, Univ. of Munich - Campus Grosshadern

Sugahara Award Ceremony of IAHO

16:30-16:35

Chairperson: Rolf D. Issels, Univ. of Munich

Sugahara Award Lecture

16:35-17:00
Chairperson: Rolf D. Issels, Univ. of Munich

Hyperthermia anno 2012: quality must be controlled and accurately documented
Gerard C. van Rhoon
Erasmus MC Daniel den Hoed, Dept. Radiat. Oncol., Unit Hyperthermia

Award Ceremony of ASHO

17:00-17:05
Chairperson: Hiroyuki Kuwano, President of ASHOASHO Award Lecture

17:05-17:20
Chairperson: Hiroyuki Kuwano, President of ASHO

Roles of intracellular oxidative stress in the enhancement of hyperthermia-induced apoptosis
Takashi Kondo
Dept. of Radiol. Sci., Grad. Sch. of Med. and Pharm. Sci., Univ. of Toyama

Welcome Remarks

17:20-17:25

Takeo Ohnishi, Honorary President of ICHO&JCTM 2012, President of JSTM

－ 14 －

Award Ceremony of Abe Award and JSTM Young Investigator Award

17:25-17:30

17:30-17:35

29

Chairperson: Akihisa Takahashi, ASRLD Unit, Gunma Univ.

Room A

Award Ceremony of Excellent Paper in Thermal Medicine and Int J Hyperthermia

28

Chairperson: Koichi Ito, Grad. Sch. of Eng., Chiba Univ.

17:35-17:50

Room A

Chairperson: Koichi Ito, Grad. Sch. of Eng., Chiba Univ.

29

Abe Award Lecture

Kanji Katayama1, Makoto Murakami2, Mitsuhiro Morikawa2, Katsuji Sawai2, Kenji Koneri2, Yasuo
Hirono2, Takanori Goi2, Atsushi Iida2, Akio Yamaguchi2

Room B

Cancer Care Promotion Center, Univ. of Fukui, 2Surgery 1, Univ. of Fukui

29

Surgery and hyperthermia

1

17:50-18:10

Room C

Chairperson: Koichi Ito, Grad. Sch. of Eng., Chiba Univ.

30

Report of JSTM Young Investigator Award

Hyperthermia enhances the efficacy of adoptive naive T-cell therapy

JSTM-YIA2

18:10-18:20

Chairperson: Akihisa Takahashi, ASRLD Unit, Gunma Univ.
18F-fluorodeoxyglucose positron tomography is useful in evaluating the efficacy of multidisciplinary
treatments for so-called borderline unresectable pancreatic head cancers
Makoto Murakami, Kanji Katayama, Kenji Koneri, Yasuo Hirono, Takanori Goi, Atsushi Iida,
Akio Yamaguchi
First Dept. of Surg., Univ. of Fukui, Sch. of Med.

－ 15 －

Room BAward Lecture for Excellent Paper in Thermal Medicine

31

Dept. of Radiology, Univ. of Occupational and Environmental Health, 2Dept. of Cancer Therapy
Center, Tobata Kyoritsu Hosp.
1

Room A

Takayuki Ohguri1, Hajime Imada2, Katsuya Yahara1, Yukunori Korogi1

31

Re-irradiation plus regional hyperthermia for recurrent non-small cell lung cancer: A potential
modality for inducing long-term survival in selected patients

Room B

Dept. of Molecular Gastroenterology and Hepatology, Kyoto Pref. Univ. of Med.

30

Satoko Adachi, Sotoshi Kokura, Takeshi Ishikawa, Naoyuki Sakamoto, Tetsuya Okayama, Reiko
Tsuchiya, Yuji Naito, Toshikazu Yoshikawa

Room A

JSTM-YIA1

Award Lecture for Excellent Paper in Int J Hyperthermia

18:20-18:30

Chairperson: Akihisa Takahashi, ASRLD Unit, Gunma Univ.
Hyperthermia enhances the effect of β-lapachone to cause γH2AX formations and cell death inhuman osteosarcoma cells
Takeshi Hori1, Takashi Kondo2, Chang W Song3
Dept. of Orthop. Surg., Fac. of Med., Univ. of Toyama, 2Dept. of Radiological Sci., Grad. Sch. ofMed. and Pharm. Sci., Univ. of Toyama, 3Radiat. Biology Lab., Dept. of Therapeutic Radiology,
Univ. of Minnesota Med. Sch.
1

Special Performance of Music

18:30-19:00－ 16 －

August 29 (Wed.)

Room A

9:10-9:40

Room A

Ceremony & Lecture29

Dept. Experimental Clinical Oncol., Aarhus Univ.
Hosp.

Room A

Chairperson: Michael R. Horsman

28

ESHO BSD Award Session

29

Symposium 1

9:50-11:50

29

9:40-9:50

Org. to Support Peritoneal Dissemination Treatment

Hyperthermic intraperitoneal chemotherapy with gastrectomy and lymphadenectomy for thetreatment of gastric cancer patients with peritoneal carcinomatosis

30

Hiroshi Yamamoto, Satoshi Murata, Tsuyoshi Yamaguchi, Eiji Mekata, Tomoharu Shimizu, Hiromichi
Sonoda, Hisanori Shiomi, Shigeyuki Naka, Hiroya Akabori, Koichiro Murakami, Tohru Tani

Room B
31

Takanori Goi, Kanji Katayama, Toshiyuki Nakazawa, Katsuji Sawai, Mitsuhiro Morikawa, Atsushi
Iida, Akio Yamaguchi

Room A

MUC2 protein expression status is useful in judging the effects of HIPEC for peritoneal
dissemination of colon cancer

31

Dept. of Surg., Shiga Univ. of Med. Sci.
S01-2

Room A

Shigeki Kusamura

Dept. of Surg., Fondazione IRCCS Istituto
Nazionale dei Tumori di Milano

30

Chairpersons: Yutaka Yonemura

Room CHIPEC for peritoneal dissemination today

S01-1

Room B

BreakFirst Dept. of Surg., Univ. of Fukui
Laparoscopy assisted hyperthermic intraperitoneal chemotherapy and gastrectomy combined
peritonectomy for advanced gastric cancer with peritoneal carcinomatosis
Masumi Ichinose1, Yutaka Yonemura2, Nobuyuki Takao1, Akiyoshi Mizumoto1, Masamitsu Hirano1
Dept. of General Surg., Kusatsu General Hosp., 2NPO Org. to Support Peritoneal Dissemination Treatment

1

S01-4

Safety and survival after cytoreductive surgery with peritonectomy procedures and hyperthermic
intraperitoneal chemotherapy
Emel Canbay, Yutaka Yonemura
Peritoneal Surface Malignancy Treatment Center, Kishiwada Tokushukai Hosp., Kishiwada City,
Osaka Japan－ 17 －

Room B

S01-3

S01-5

Clinical outcomes of laparoscopic hyperthermic intraperitoneal chemotherapy (LHIPEC) instomach and colorectal cancer patients with peritoneal carcinomatosis
Chai Young Lee1, Hyun Choon Shin2, Yoon Hee Park2, Jeong Ho Lee3, Jin Ho Choi2, Jeong Ho
Seo2, Seh Jong Park2, Dae Hee Lee2
Dept. of Oncologic Surg., Anyang Sam Hosp. Integrative Cancer Center, 2Dept. of Hematology
and Oncol., Anyang Sam Hosp. Integrative Cancer Center, 3Dept. of Family Med., Anyang Sam
Hosp. Integrative Cancer Center
1

S01-6

Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for peritoneal
metsastases from appendix and colon cancer: Current perspectives and future trends
Lana Bijelic
Dept. of Surg., Washington Hosp. Center, Washington DC

S01-7

Cytoreductive surgery with HIPEC in diffuse malignant peritoneal mesothelioma, epithelial
ovarian cancer and peritoneal sarcomatosis: current evidence
Shigeki Kusamura, Dario Baratti, Marcello Deraco
Dept. of Surg., Fondazione IRCCS Istituto Nazionale dei Tumori di Milano

Break

11:50-12:00

Luncheon Seminar 1

12:00-13:00
Chairperson: Kazuhide Higuchi

2nd Dept. of Internal Med., Osaka Med. Coll.

LS1

Protective role for HSP70 against various gastrointestinal diseases and other diseases
Tohru Mizushima
Dept. of Analytical Chem., Fac. of Pharm., Keio Univ.
Sponsored by Eisai Co., Ltd.

Symposium 2

13:00-15:00

Clinical aspects of regional hyperthermia combined with radiotherapy
Chairpersons: Yasumasa NishimuraDept. of Radiat. Oncol. Kinki Univ. Fac. of Med.

Jacoba van der Zee

Hyperthermia Unit, Dept. Radiat. Oncol., Erasmus
MC - Daniel den Hoed Cancer Center

S02-1

Review of clinical experience with radiotherapy and hyperthermia in pelvic tumours
Jacoba van der Zee
Hyperthermia Unit, Dept. Radiat. Oncol., Erasmus MC - Daniel den Hoed Cancer Center－ 18 －

S02-2Hyperthermo-chemoradiotherapy with regional hyperthermia, pelvic radiotherapy, infusional
5-fluorouracil and l-leucovorin for patients with locally advanced lower rectal carcinoma
Jun-ichi Saitoh1, Hiroki Kiyohara1, Mariko Shioya1, Yoshiyuki Suzuki1, Takashi Nakano1, Hideyuki
Sakurai2, Takeo Takahashi3, Souichi Tsutsumi4, Takayuki Asao4, Hiroyuki Kuwano4

28

Dept. of Radiat. Oncol., Gunma Univ. Grad. Sch. of Med., 2Dept. of Radiat. Oncol., Univ. of
Tsukuba, 3Dept. of Radiat. Oncol., Saitama Med. Center, 4Dept. of General Surg. Sci., Gunma
Univ. Grad. Sch. of Med.

Room A1

29

Six long-term survivors among 14 cases with malignant pleural mesothelioma (MPM) treatedwith intrathoracic chemotherapy, hyperthermia and radiation therapy

Dept. of Radiology, Tokyo Metropolitan Cancer and Infectious diseases Center Komagome Hosp.
The role of hyperthermia in the treatment of locally advanced prostate cancer

S02-5

Poster-Short Oral pr. 01

15:15-18:00

31

15:00-15:15

Shin Ohta1, Hajime Imada1, Hiroyuki Narisada1, Yoshinori Tomoda1, Katsuya Yahara2, Takayuki
Ohguri2, Takeshi Kobayashi3
Cancer Therapy Center, Tobata Kyoritsu Hosp., 2Dept. of Radiology, Univ. of Occupational andEnvironmental Health, Kitakyushu, Japan, 3Chubu Univ.
1

Pa-02

Hyperthermia for protruded tumor from the skin
Shin Ohta1, Hajime Imada1, Hiroyuki Narisada1, Yoshinori Tomoda1, Katsuya Yahara2, Takayuki
Ohguri2
Cancer Therapy Center, Tobata Kyoritsu Hosp., 2Dept. of Radiology, Univ. of Occupational andEnvironmental Health, Kitakyushu, Japan
1－ 19 －

Room BA case of submandibular gland carcinoma treated with chemo-radiotherapy plus hyperthermia
using magnetite nanoparticle-loaded liposome

31

Dept. of Radiat. Oncol., Tokyo Kousei Nenkin
Hosp.

Room A

Chairperson: Hiromasa Kurosaki

Pa-01

Room B

Break

30

Med. clinic III, Univ. of Munich, LMU, 2Clinical Cooperation Group Hyperthermia, Helmholtz
Zentrum, Munich, 3Dept. of Surg., Univ. of Munich, LMU, 4HäCmato-Onkologische
Schwerpunktpraxis, Munich, 5IBE, Univ. of Munich, LMU
1Room A

Katharina E. Lechner1,2, Christiane Bruns3, Nelli Dieterle1, Lars Lindner1,2, Sultan Abdel-Rahman1,
Christoph Salat4, Volker Heinemann1, Ulrich Mansmann5, Wolfgang Hiddemann1, Rolf D. Issels1,2

30

Gemcitabine, cisplatin combined with hyperthermia in pancreatic cancer: Retrospective data
and two ongoing clinical trials

Room C

Dept. of Radiotherapy Univ. Hosp. of Verona

29

Sergio Maluta, Stefano Dall’Oglio, Mario Palazzi, Fabio Pioli, Antonio Grandinetti, Mario Romano,
Nadia Marciai, Milena Gabbani, Anna D’Amico

Room B

S02-4

29

Katsuyuki Karasawa, Takuya Shimizuguchi, Shun-ichirou Kageyama, Hiroshi Tanaka, Hiromi
Izawa, Yumiko Machitori, TaChen Chang, Masakatsu Onozawa, Keiji Nihei, Nahoko Hanyu

Room A

S02-3

Pa-03Novel hyperthermia using magnetic materials for metastatic bone tumors
Kunihiro Asanuma, Akihiko Matsumine, Takao Matsubara, Toru Ooi, Atsumasa Uchida, Akihiro
Sudo
Dept. of Orthop. Surg. Mie Univ. Grad. Sch. of Med.

Pa-04

Palliative chemo-hyperthermia for primary or post-operative gastric carcinoma with organ
metastasis or peritoneal dissemination
Hajime Imada, Hiroyuki Narisada, Yoshinori Tomoda, Shin Ohta
Cancer Therapy Center, Tobata Kyoritsu Hosp.

Pa-05

The investigation of cases with long term chemo-hyperthermia of same regimen
Hiroyuki Narisada, Hajime Imada, Yoshinori Tomoda, Shin Ohta
Cancer Therapy Center, Tobata Kyoritsu Hosp.

Pa-06

Chemo-hyperthermia for pre-end stage recurrent ovarian cancer
Hiroyuki Narisada, Hajime Imada, Yoshinori Tomoda, Shin Ohta
Cancer Therapy Center, Tobata Kyoritsu Hosp.

Pa-07

Retrospective analysis of combined modality therapy for unresectable soft tissue sarcoma,
clinical outcome of 14 cases
Takuya Shimizuguchi, Katsuyuki Karasawa
Cancer and Infectious Disease Center Tokyo Metropolitan Komagome Hosp.

Poster-Short Oral pr. 02

15:15-18:00
Chairperson: Hideaki Takahashi

Section of Neurosurgery, Niigata Cancer Center
Hosp.

Pa-08

An advanced pancreatic cancer patient treated with a combination of proton beam therapy,
chemotherapy and hyperthermia: Case report
Mikako Harada, Takeshi Arimura, Takashi Ogino, Yoshio Hishikawa
Medipolis Proton Therapy and Res. Center

Pa-09

Intraoperative hyperthermia for metastatic brain tumors
Seung Hoon Lee1, Heon Yoo1, Yung Ho Jo2, Ho Shin Gwak1, E Suk Yang1, Sang Hoon Shin1
1

Pa-10

Neurooncology Clinic, Nat’l Cancer Center, 2Branch of Biomed. Eng., Nat’l Cancer Center

Survival analysis of radiofrequency ablation combined with liver resection for dual lobe
multifocal hepatocellular carcinoma
Kuansheng Ma, Jun Yan, Xiaowu Li, Feng Xia, Xiaobin Feng, Li Liu, Ping Bie
The Inst. of Hepatobiliary Surg., Southwest Hosp., Third Military Med. Univ, Chongqing,
P.R.China－ 20 －

Pa-11

Early tolerance of interstitial prostate hyperthermia in combination with HDRbrachytherapy
28Andrzej Kukielka1,2, Piotr Brandys2, Tomasz Dabrowski1,2, Tomasz Walasek1,2
Dept. of Brachytherapy, Centrum Onkologii - Instytut im. M. Sklodowskiej-Curie, Oddzial Krakow,
Dept. of Radiotherapy, Centrum Onkologii - Instytut im. M. Sklodowskiej-Curie, Oddzial Krakow

1

Efficacy of intrathoracic thermochemotherapy for the treatment of malignant effusion in patientswith non-small cell lung cancer
Dept. of General Surgical Sci., Gunma Univ. Grad. Sch. of Med.

Kosuke Ueda1, Fumiko Maeda1, Yasuhiko Ito2
Nagoya Prostatic Center, Hachiya Orthop. Hosp., 2Dept. of Urology, Holy Spirit Hosp.

1

Alexei Suvernev1,2, George Ivanov1, Milton Yatvin2,3
Siberian Sci. Res. Inst. of Hyperthermia, 2Heatheal, Washington DC, USA, 3Biology Dept. Reed
Coll., Portland OR, USA

Room C

Immunological enhancement and long term remissions achieved in HIV patients receiving HLWBH ‘heatheal’ hyperthermia treatment

29

Pa-14

Room B

Castration-resistant prostate cancer treated with combining low dose chemotherapy and regional
hyperthermia for obtaining long survival

29

Pa-13

Room A

Akira Mogi, Takayuki Kosaka, Ei Yamaki, Shigebumi Tanaka, Hiroyuki Kuwano

29

Pa-12

Room A

2

1

Pa-15

Dept. of Oral and Maxillofacial Surg., Yokohama City Univ. Grad. Sch. of Med., 2Dept. of Oraland Maxillofacial Surg., Nagoya Univ. Grad. Sch. of Med.
1

Room A

Kenji Mistudo1, Toshiyuki Koizumi1, Masaki Iida1, Toshinori Iwai1, Senri Oguri1, Noriyuki
Yamamoto2, Minoru Ueda2, Mitomu Kioi1, Makoto Hirota1, Iwai Tohnai1

31

Thermochemoradiotherapy using superselective intra-arterial infusion via superficial temporaland occipital arteries for oral cancer with N3 cervical lymph node metastases

Room B

Dept. of General Surgical Sci., Grad. Sch. of Med.,
Gunma Univ.

30

Chairperson: Takayuki Asao

Room A

15:15-18:00

30

Poster-Short Oral pr. 03

31

Clinical application of oncothermia against the tumors developed in the deep tissues in veterinary
medicine
Yoshiharu Okamoto, Gabor Andocs, Tomohiro Osaki, Takeshi Tsuka, Tomohiro Imagawa, Saburo
MinamiDept. of Veterinary Clinical Med., Fac. of Agric., Tottori Univ.

Pa-17

Chemo-hyperthemia for non-small cell lung cancer with multiple pulmonary metastases
Hajime Imada1, Hiroyuki Narisada1, Yoshinori Tomoda1, Shin Ohta1, Katsuya Yahara2, Takayuki
Ohguri2
Cancer Therapy Center, Tobata Kyoritsu Hosp., 2Dept. of Radiology, Univ. of Occupational andEnvironmental Health, Kitakyushu, Japan1－ 21 －

Room B

Pa-16

Pa-18Superficial hyperthermia in head and neck malignancies. A review of 164 patients
Stefano Dall’Oglio1, Mario Palazzi1, Andrea Fior2, Mario Romano1, Nadia Marciai1, Sergio Maluta1
Dept. of Radiat. Oncol., Univ. Hosp., Verona, Italy, 2Section of Oral and Maxillo-facial Surg.,
Dept. of Surg., Univ. Hosp., Verona, Italy

1

Pa-19

Results of chemothermoradiation therapy for locally advanced laryngeal cancer
Orazakhmet Kurpeshev1, Vyacheslav Andreyev2, Vladimir Pankratov2, Igor Gulidov3, Kamila
Strelkova1
Dept. of Hyperthermia, Med. Radiological Res. Center, 2Dept. of Oncological Oto-RhinoLaryngology, Med. Radiological Res. Center, 3Dept. of Radiat. Therapy, Med. Radiological Res.
Center1

Pa-20

Clinical evaluation of thermochemoradiotherapy for advanced head and neck cancer
Masaki Iida1, Kenji Mitsudo1, Toshiyuki Koizumi1,2, Toshinori Iwai1, Senri Oguri1, Mitomu Kioi1,
Makoto Hirota1, Hideyuki Nakashima1, Iwai Tohnai1
Dept. of Oral and Maxillofacial Surg., Yokohama City Univ. Grad. Sch. of Med., 2Dept. of Oraland Maxillofacial Surg., Tokyo Med. Univ.
1

Pa-21

Thermochemoradiotherapy using superselective intra-arterial infusion via superficial temporaland occipital arteries for advanced oral cancer with cervical lymph node metastases
Toshiyuki Koizumi1, Kenji Mitsudo2, Masaki Iida2, Toshinori Iwai2, Senri Oguri2, Mitomu Kioi2,
Makoto Hirota2, Iwai Tohnai2
Dept. of Oral and Maxillofacial Surg., Fac. of Med., Tokyo Med. Univ., 2Dept. of Oral andMaxillofacial Surg., Yokohama City Univ. Grad. Sch. of Med.

1

Poster-Short Oral pr. 04

15:15-18:00
Chairperson: Hideo Baba

Dept. of Gastroenterological Surg. Grad. Sch. ofMed. Sci. Kumamoto Univ.

Pa-22

Multidisciplinary therapy including hyperthermia for colorectal cancer
Hiroyuki Narisada, Hajime Imada, Yoshinori Tomoda, Shin Ohta
Cancer Therapy Center, Tobata Kyoritsu Hosp.

Pa-23

Chemo-radiotherapy plus regional hyperthermia and hyperbaric oxygen therapy for locallyadvanced pancreatic carcinoma
Hiroyuki Narisada1, Hajime Imada1, Yoshinori Tomoda1, Shin Ohta1, Katsuya Yahara2, Takayuki
Ohguri2
Cancer Therapy Center, Tobata Kyoritsu Hosp., 2Dept. of Radiology, Univ. of Occupational andEnvironmental Health, Kitakyushu, Japan
1

Pa-24

Efficacy of neoadjuvant termochemotherapy in localized and locally advanced breast cancers
Orazakhmet Kurpeshev
Dept.of Hyperthermia, Med. Radiological Res. Center－ 22 －

Pa-25

Local control rate after the combination of re-irradiation and hyperthermia for recurrent breast
cancer: Results in 250 patients28

Dept. of Radiat. Oncol., Hyperthermia Unit, Erasmus MC-Daniel den Hoed Cancer Center, 2Dept.
of Surgical Oncol., Erasmus MC-Daniel den Hoed Cancer Center, 3Dept. of Radiat. Oncol., Erasmus
MC-Daniel den Hoed Cancer Center, 4Dept. of Trial and Med. Statistics, Erasmus MC-Daniel den
Hoed Cancer Center

Room A

1

Radio-hyperthermia (RT-HT) in the retreatment of superficial breast cancer recurrences

Dept. of Radiat. Oncol., San Camillo Forlanini Hosp., Rome
Chemo-radiation using paclitaxel and carboplatin plus regional hyperthermia for stage III
non-small cell lung cancer

29

Cancer Therapy Center, Tobata Kyoritsu Hosp., 2Dept. of Radiology, Univ. of Occupational andEnvironmental Health, Kitakyushu, Japan

Room C

Chemo-radiotherapy plus regional hyperthermia and hyperbaric oxygen therapy for locallyadvanced or post-operative loco-regional recurrence of gastric carcinoma

30

Hajime Imada, Hiroyuki Narisada, Yoshinori Tomoda, Shin Ohta
Cancer Therapy Center, Tobata Kyoritsu Hosp.

Room A

Hajime Imada1, Hiroyuki Narisada1, Yoshinori Tomoda1, Shin Ohta1, Katsuya Yahara2, Takayuki
Ohguri21

Pa-28

Room B

Pa-27

29

Giovanni De Pascalis, Alessia Monaco, Cristina Caruso, Michele Cianciulli, Cinzia Chiostrini,
Vittorio Donato

Room A

Pa-26

29

Marianne Linthorst1, Albert N van Geel2, Margreet Baaijens3, Wendim Ghidey4, Gerard C van
Rhoon1, Jacoba van der Zee130

15:15-18:00
Chairperson: Takefumi Ohga

Usefulness of combined treatment with continuous tirapazamine administration and mild
temperature hyperthermia in gamma-Ray irradiation, referring to lung metastatic potential

Pa-30

Re-irradiation plus hyperthermia for recurrent breast cancer in previously irradiated area;
size matters!
Sabine Oldenborg1, Vanessa Griesdoorn1, Yoka Kusumanto1, Rob van Os1, Bing Oei2, Jack
Venselaar2, Hans Crezee1, Paul Zum Vorde1, Coen Rasch1, Geertjan van Tienhoven1
Academic Med. Center, Dept. of Radiat. Oncol., Amsterdam, 2Inst. Verbeeten, Dept. of Radiat.
Oncol., Tilburg, the Netherlands

1－ 23 －

Room B

Particle Radiat. Oncol. Res. Center, Res. Reactor Inst., Kyoto Univ., 2Radiat. Med. Phys., Res.
Reactor Inst., Kyoto Univ.

1

31

Shin-ichiro Masunaga1, Yoshinori Sakurai2, Hiroki Tanaka2, Minoru Suzuki1, Natsuko Kondo1,
Masaru Narabayashi1, Akira Maruhashi2, Koji Ono1

Room A

Pa-29

31

Fukuoka Higashi Med. Center, Dept. of Surg.

Room B

Poster-Short Oral pr. 05

Pa-31Comparison of 4 to 8 hyperthermia treatments combined with re-irradiation for breast cancer
Marianne Linthorst1, Gerard C van Rhoon1, Margreet Baaijens2, Wendim Ghidey3, Jacoba van derZee1
Dept. of Radiat. Oncol., Hyperthermia Unit, Erasmus MC-Daniel den Hoed Cancer Center, 2Dept.
of Radiat. Oncol., Erasmus MC-Daniel den Hoed Cancer Center, 3Dept. of Trial and Med. Statistics,
Erasmus MC-Daniel den Hoed Cancer Center
1

Pa-32

Whole body hyperthermia combined with chemotherapy and radiotherapy for the treatmentof patients with advanced stage nasopharyngeal carcinoma
Xunfan Shao, Jingfeng Deng, Naiying Zheng, Jianjun Shi, Zhiwen Mo
Dept.of Radiat. Oncol., Guangzhou Med. Coll. affiliated Cancer Hosp.

Pa-33

Efficacy of sequential combination of hyperthermia and gemcitabine in the treatment of advanced
pancreatic cancer: Phase II study
Takeshi Ishikawa1,2, Satoshi Kokura1,2, Naoyuki Sakamoto3, Reiko Tsuchiya2, Manabu Okajima2,
Tatsuzo Matsuyama2, Satoko Adachi1, Tetsuya Okayama1,2, Nobuaki Yagi2, Yuji Naito2, Toshikazu
Yoshikawa1
Dept. of Cancer Immunocell Regulation, Kyoto Pref. Univ. of Med., 2Dept. of Gastroenterology
and Hepatology, Kyoto Pref. Univ. of Med., 3Iseikai Hyakumanben Clinic

1

Pa-34

Clinical research of hyperthermic intraperitoneal perfusion chemotherapy combined with veinchemotherapy in treating advanced colon cancer
Shenglin Ma, Zhibing Wu, Xiadong Li, Yuelong Pan
Dept. of Radiat. Oncol., The first People’s Hosp. of Hangzhou

Poster-Short Oral pr. 06

15:15-18:00
Chairperson: Masaru Morita

Dept. of Surg. and Sci., Kyushu Univ.

Pa-35

Radiotherapy of cervical carcinoma: combined with hyperthermia or chemotherapy? Resultsof the RADCHOC study
Ludy C Lutgens1, Jan J Jobsen2, Elzbieta M van der Steen3, Helena C van Doorn4, Gerard C van
Rhoon5, Jacoba van der Zee5
Maastro Clinic, Maastricht, 2Dept. of Radiat. Oncol., Medisch Spectrum Twente, Enschede, theNetherlands, 3ARTI, Arnhem, the Netherlands, 4Dept. of Gynaecologic Oncol., Erasmus MC,
Rotterdam, the Netherlands, 5Dept. of Radiat. Oncol., Hyperthermia Unit, Erasmus MC, Rotterdam,
the Netherlands
1

Pa-36

Long-term outcome and efficacy of hyperthermochemotherapy for residual recurrence
esophageal cancer after definitive chemoradiotherapy
Yasue Kimura1, Masaru Morita2, Koji Ando1, Satoshi Ida1, Hiroshi Saeki1, Eiji Oki1, Tetsuya
Kusumoto1, Yoshiyuki Shioyama2, Yoshihiko Maehara1
Dept. of Surg. and Sci., Grad. Sch. of Med. Sci., Kyushu Univ., 2Dept. of Clinical Radiology,
Grad. Sch. of Med. Sci., Kyushu Univ.
1－ 24 －

Pa-37

Early response to neo-adjuvant chemotherapy (NAC) in combination with regional hyperthermia(RHT) predicts long-term survival
Lars H. Lindner1, Eric Kampmann1, Nelli Dieterle1, Ulrich Mansmann2, Thomas Kirchner3, Rolf
D. Issels1

28

Univ. Hosp. Med. Center - Medizinische Klinik III, 2Inst. of Med. Informatics, Biostatistics, andEpidemiology, Univ. of Munich, 3Inst. of Pathology, Ludwig-Maximilian-Univ. Munich

Room A1

The clinical study of tumor local hyperthermia treatment for 808 cases

29

Pa-38

Room A

Yingquan Cai
Dept. of Radiotherapy Center, Shanxi Provincial Tumor Hosp.
Local control rate after the combination of surgery, re-irradiation and hyperthermia for radioinduced angiosarcoma of the chest wall

29

Marianne Linthorst1, Albert N van Geel2, Cees Verhoef2, Elizabeth Baartman3, Bing Oei4, Wendim
Ghidey5, Gerard C van Rhoon1, Jacoba van der Zee1

Room B

Pa-39

Dept. of Radiat. Oncol., Hyperthermia Unit, Erasmus MC-Daniel den Hoed Cancer Center, 2Dept.
of Surgical Oncol., Erasmus MC-Daniel den Hoed Cancer Center, 3Dept. of Radiat. Oncol., Erasmus
MC-Daniel den Hoed Cancer Center, 4Dept. of Radiat. Oncol., Verbeeten Inst., 5Dept. of Trial andMed. Statistics, Erasmus MC-Daniel den Hoed Cancer Center
1

Introduction of HIPEC for treating peritoneal surface malignancy at a community hospital

Dept. of Surg., Kishiwada City Hosp.

Room B

Toshiyuki Kitai, Masafumi Kogire, Katusyoshi Furumoto, Daisuke Ito, Tomohiko Mori, Hidenobu
Kojima, Yuya Miyauchi, Daisuke Nagashima

30

Pa-41

Room A

Inst. for Res. and Treatment of Cancer, Candiolo (TO) Italy30

Rocco Panaia, Amalia Di Dia, Gabriele Petrilli, Giovanni Penduzzu, Pietro Gabriele

Room CA methodological approach to the treatment of multiple/large lesions with 434 MHz hyperthermia
and tomotherapy

29

Pa-40

31

15:15-18:00
Chairperson: Erito Mochiki

Pa-42

Satoshi Murata1, Hiroshi Yamamoto1, Tsuyoshi Yamaguchi1, Hiroyuki Naitoh2, Tomoharu Shimizu1,
Hisanori Shiomi1, Shigeyuki Naka1, Hiromichi Sonoda1, Eiji Mekata1, Hajime Abe1, Tohru Tani1
Dept. of Surg., Shiga Univ. of Med. Sci., 2Dept. of Surg., Hino Memorial Hosp.

1－ 25 －

Room B

Hyperthermic intraperitoneal chemotherapy (HIPEC) following a curative resection of advanced
gastric cancer

31

Dept. of General Surg. Sci., Gunma Univ.

Room A

Poster-Short Oral pr. 07

Pa-43Temperature dependence of magnetic resonance signals of lipid proton components and its
application to fat thermometry
Kagayaki Kuroda1,2, Shuhei Morita1, Khalid Albarodi2, Makoto Obara3, Paul Baron4, Mie Kee
Lam4, Wilbert Bartels4, Masatoshi Honda3, Tomohiko Horie5, Yutaka Imai5
Dept. of Human and Information Sci., Sch. of Information Sci. and Tech., Tokai Univ., 2Courseof Information Sci. and Tech., Grad. Sch. of Eng., Tokai Univ., 3MR Marketing, Philips Electronics
Japan Med. Systems, Shinagawa, Tokyo, Japan, 4Image Sci. Inst., Univ. Med. Center Utrecht,
Utrecht, Netherlands, 5Dept. of Radiology, Tokai Univ., Japan
1

Pa-44

Clinically significant urethral stricture and/or subclinical urethral stricture after HIFU
paradoxically correlates with disease-free survival in patients with prostate cancer
Teruo Inamoto1, Hiroshi Masuda1,4, Kazumasa Komura1, Yutaka Fujisue1, Peter Black2, Toshikazu
Watsuji3, Haruhito Azuma1
Dept. of Urology, Osaka Med. Coll., Osaka, Japan, 2Dept. of Urologic Sci., Univ. of British
Columbia, Vancouver, British Columbia, Canada, 3Dept. of Urology, Hirakata City Hosp., Osaka,
Japan, 4Dept. of Urology, Aino Hosp., Osaka, Japan

1

Pa-45

The thermal combinational therapy with whole body hyperthermia and thermal coagulation
for metastatic tumor
Akira Takeuchi, Hiromi Hasumura, Masakazu Shirahige, Sachiko Kotoyori, Kimiko Kume, Yoko
Okawa, Takashi Takeuchi
Dept. of Thermotherapy, Luke Clinic

Pa-46

Enhancement of ultrasound- or hyperthermia-induced cancer cell killing by antibacterial
agentsLoreto B. Feril1, Katsuro Tachibana1, Takashi Kondo2, Ryohei Ogawa2, Zheng-Guo Cui3
Dept. of Anatomy, Fukuoka Univ. Sch. of Med., 2Dept. of Radiological Sci., Fac. of Med., Univ.
of Toyama, 3Dept. of Public Health, Fac. of Med., Univ. of Toyama

1

Pa-47

Improved intratumoral distribution of temperature sensitive liposomes and doxorubicin after
combined hyperthermia and ablation treatment
Nicole Hijnen1, Mariska de Smet1, Holger Gruell1,21Eindhoven Univ. of Tech., 2Philips Res. Eindhoven, the Netherlands
Room P

Poster Viewing & Discussion

18:00-19:00－ 26 －

August 29 (Wed.)

Room B

8:40-9:10
Dokkyo Med. Univ. First Dept. of Surg.

Cancer hyperthermia using magnetite nanoparticles

29

ML01

Room A

Takeshi Kobayashi
Sch. of Biosci. and Biotech., Chubu Univ.

9:10-9:40

Influence of thermal therapy on the tumor microenvironment, vascular function and vice-versa

29

Dept. of Radiat. Oncol., Tokyo Women’s Univ. Sch.
of Med.

Room B

Chairperson: Norio Mitsuhashi

29

Morning Lecture 2

ML02

Room A

Chairperson: Hiroyuki Kato

28

Morning Lecture 1

Room C

Robert J. Griffin
Univ. of Arkansas for Med. Sci.

30

Symposium 3

9:50-11:50

Chairpersons: Hiroyuki Honda

Dept. of Biotech., Grad. Sch. of Eng., Nagoya Univ.

Magnetic anti-cancer compound in hyperthermic therapy
Yoshihiro Ishikawa1, Haruki Eguchi2

Proteins and cholesterol lipid vesicles are mediators of drug release from thermosensitive liposomes
Martin Hossann1,2, Zulfiya Syunyaeva1, Rebecca Schmidt1, Anja Zengerle1, Hansjoerg Eibl3, Rolf
D. Issels1,2, Lars H. Lindner1,2
Dept. of Internal Med. III, Univ. Hosp. Grosshadern, Ludwig- Maximilians Univ., Munich, 2CCG
Hyperthermia, Helmholtz Zentrum Muenchen, German Res. Center for Environmental Health,Munich, Germany, 3Max-Planck-Inst. for Biophysical Chem., Goettingen, Germany

1

S03-3

Heat sensitive nanomedicine in oncology: A clinical review of lyso-thermosensitive liposomal
doxorubicin
Nicholas Borys
Celsion Corp.
－ 27 －

Room B

S03-2

31

Cardiovascular Res. Inst., Yokohama City Univ., Grad. Sch. of Med., 2Advanced Applied Sci.
Dept., Res. Lab., IHI Co., Yokohama, Japan1

Room A

S03-1

31

Nicholas Borys

Celsion Corp.

Room B

Hyperthermia and nanotechnology / nanomedicine30

9:40-9:50

Room ABreakS03-4

Combined therapy of magnetite nanoparticles and NPrCAP, melanogenesis substrate, provides
melanoma-targeted in situ vaccine by chemo-thermo-immunotherapy
Kowichi Jimbow1, Akihiro Yoneta1, Yasuaki Tamura1, Toshiharu Yamashita1, Akira Ito2, Hiroyuki
Honda2, Kazumasa Wakamatsu3, Shosuke Ito3, Satoshi Nohara4, Takeo Hasegawa5, Itsuo
Yamamoto5
Sapporo Med. Univ, Sch. of Med., 2Sch. of Eng., Nagoya Univ., 3Fujita Health Univ. Sch. of HealthSci., 4Meito Sangyo Co., Ltd., 5Yamamoto Vinita Co., Ltd.
1

S03-5

A novel two-step of local mild hyperthermia approach for advanced liposomal drug delivery tosolid tumors
Li Li1, Timo LM Ten Hagen1, Astrid Gasselhuber2, Jeremy Yatvin2, Michiel Bolkestein1, Gerard van
Rhoon3, Alexander MM Eggermont1,4, Martin Hossann5, Dieter Haemmerich2, Gerben A Koning1
Dept. of Surg., Erasmus Med. Center, 2Dept. of Pediatrics, Coll. of Med., Med. Univ. of South
Carolina, 3Dept. of Radiotherapy, Erasmus Med. Center - Daniel den Hoed Cancer Center, 4Inst.
of Cancerology Gustave Roussy, 5Dept. of Internal Med. III, Univ. Hosp. Grosshadern
1

S03-6

Effects of platinum nanoparticles on LPS-induced inflammatory response and hyperthermiainduced apoptosis
Mati Ur Rehman1, Yoko Yoshihisa1, Yusei Miyamoto2, Tadamichi Shimizu1
Dept. of Dermatology, Grad. Sch. of Med. and Pharm. Biosci. Univ. of Toyama, Japan, 2Dept. ofIntegrated Biosci., Grad. Sch. of Frontier Sci., Univ. of Tokyo, Chiba, Japan

1

S03-7

Drug-loaded magnetic nanocomposite devices for cancer thermochemotherapy
Lingyun Zhao1, Zhu Yao2, Li Li3, Jingdingsha Li2, Jintian Tang1
Inst. of Med. Physics and Eng., Dept. of Eng. Physics, Tsinghua Univ., Beijing, 2Dept. ofBiopharmaceutical, Beijing Univ. of Chinese Med., Beijing, 100102, China, 3Dept. of Oncol.,Xiangya Hosp., Central South Univ., Changsha, Hunan Province, PR China, 410008
1

S03-8

A novel intravesical magnetic nanoparticle hyperthermia system for treatment of bladder cancer
Alireza Mashal, Martin Huisjen, Kate McNerny, Karl Frantz, Mike Susedik, Carolyn Adams,
Andrew Updegrave, Marvin Ross, Dan McKenna
Actium Biosystems

Break11:50-12:00

Symposium 4

13:00-15:00

JSIR joint symposium: Heat stress and inflammation / regeneration
Chairpersons: Ikuo Morita

Dept. of Cellular Physiological Chem., Tokyo Med.
and Dental Univ.

Toshikazu Yoshikawa

Kyoto Pref. Univ. of Med.

S04-1

Heat shock factors negatively regulate the inflammatory response
Akira Nakai, Ryosuke Takii, Naoki Hayashida, Eiich Takaki, Mitsuaki Fujimoto
Dept. of Biochem. and Molecular Biology, Yamaguchi Univ. Sch. of Med.
－ 28 －

S04-2

Effects of application of heat stress on the regeneration of injured skeletal muscle
Yoshinobu Ohira

Identification of genes responsive to mild hyperthermia in normal human fibroblastic cells

S04-4

Heating in nano-scale: Oncothermia

29

Andras Szasz

Effects of a HSP70 inducer, alkannin on apoptosis in UVB-exposed human keratinocytes
Yoko Yoshihisa1, Mariame Ali Hassan2, Yukihiro Furusawa2, Takashi Kondo2, Tadamichi
Shimizu129

Dept. of Dermatology, Grad. Sch. of Med. and Pharm. Sci., Univ. of Toyama, 2Dept. of Radiological
Sci., Grad. Sch. of Med. and Pharm. Sci., Univ. of Toyama

Room C1

15:15-18:00
Dept. of Radiat. Oncol., Fac. of Med., Grad. Sch. ofComprehensive Human Sci., Univ.of Tsukuba

Makoto Ihara1, Kenzo Ohtsuka2, Yutaka Okumura1, Takeo Ohnishi3

Room A

Heat-inducible gene expression system using hybrid HSP70 promoter for hyperthermia genetherapy

31

Masaki Yamaguchi, Akira Ito, Noriaki Okamoto, Yoshinori Kawabe, Masamichi Kamihira
Dept. of Chem. Eng., Fac. of Eng., Kyushu Univ.
Pb-03

Heat treatment as well as X-ray-irradiation depresses gastric mucosal damage induced withrestraint plus water-immersion stress through HSP-induction in mice
Akihisa Takahashi1, Xiaoming Su2, Rikio Yamagata3, Takeo Ohnishi4
ASRLD Unit, Gunma Univ., 2306th Hosp. of PLA, 3Himeji Dokkyo Univ., 4Dept. of Radiat. Oncol.,Nara Med. Univ.
1－ 29 －

Room B

Dept. of RI Med., Atomic Bomb Disease Inst., Nagasaki Univ., 2Lab. of Cell and Stress Biol.,Coll. of Biosci. and Biotechnol., Chubu Univ., 3Dept. of Rad. Oncol., Nara Med. Univ.

1

Pb-02

31

Reactivation of heat-inactivated Ku proteins by heat shock protein HSP73

Room B

Chairperson: Hitoshi Ishikawa

30

Poster-Short Oral pr. 01

Room A

15:00-15:15

30

Break

Pb-01

Room B

St. Istvan Univ., Fac. of Eng., Biotechnics Dept.
S04-5

Room A

Life Sci. Res. Ctr., Univ. of Toyama, 2Grad. Sch. of Med. and Pharm. Sci., Univ. of Toyama, 3Dept.
of Environmental Biol., Chubu Univ.

1

29

Yoshiaki Tabuchi1, Yukihiro Furusawa2, Ayako Kariya2, Shigehito Wada2, Kenzo Ohtsuka3, Takashi
Kondo2

Room A

S04-3

28

Grad. Sch. Med. & Front. Biosci., Osaka Univ.

Pb-04Inactivation of DNA-dependent protein kinase promotes heat-induced apoptosis independentlyof heat-shock proteins in human cancer cell line
Seisuke Okazawa1,2, Yukihiro Furusawa2,3, Ayako Kariya2, Mariame Ali Hassan2, Mie Arai2, Yoshiaki
Tabuchi4, Ryuji Hayashi1, Takashi Kondo2, Kazuyuki Tobe1
Dept. of First Internal Med., Univ. of Toyama, 2Dept. of Radiological Sci., Univ. of Toyama, 3Lab.
for Bioenvironmental Epigenetics, Res. Center for Allergy and Immunology, 4Div. of Molecular
Genetics Res., Life Sci. Res. Center, Univ. of Toyama
1

Pb-05

Pifithrin-mu, a new HSP70 inhibitor, sensitizes human prostate cancer cells to hyperthermia
Kazumasa Sekihara1,4, Nanae Harashima1, Hiroyuki Monma1,2, Nobue Uchida3, Taisuke Inomata4,
Mamoru Harada1
Dept. Immunol. Shimane Univ. Facult. Med., 2Dept. of General Surg. Shimane Univ. Facult. Med.,
3
Dept. Rad. Oncol. Tottori Prefect. Center Hosp., 4Dept. Rad. Oncol. Shimane Univ. Facult. Med.
1

Pb-06

A priming heat treatment can induce the development of heat- and radio-resistance via HSPs,
regardless of p53-gene status
Akihisa Takahashi1, Takeo Ohnishi2
ASRLD Unit, Gunma Univ., 2Dept. of Radiat. Oncol., Nara Med. Univ.

1

Poster-Short Oral pr. 02

15:15-18:00
Chairperson: Ichiro Ota

Dept. of Otolaryngology-Head and Neck Surg., Nara
Med. Univ.

Pb-07

Heat induced cell death and HSPs in human leukemia cell lines
Qing-Li Zhao, Yoshisada Fujiwara, Takashi Kondo
Dept. Radiol. Sci., Univ. of Toyama, Grad. Sch. Med. Pharm

Pb-08

Gene expression profiling in HSF1-knockdown human oral squamous cell carcinoma HSC-3 cells
Tatsuya Yunoki1, Yoshiaki Tabuchi2, Ayako Kariya1, Takashi Kondo1
Grad. Sch. of Med. and Pharm. Sci., Univ. of Toyama, 2Life Sci. Res. Ctr., Univ. of Toyama

1

Pb-09

Beneficial effects of molecular chaperone inducers
Kenzo Ohtsuka
Lab. Cell & Stress Biol., Dept. Environmental Biol., Chubu Univ.

Pb-10

Immunomolecular characteristics of triple-negative breast cancer stem cells
Punit Kaur1, Sunil Krishnan2, Alexzander Asea1
Dept. of Pathology, Scott & White Memorial Hosp. and Clinic, and the Texas A&M Health Sci.
Center, 2Dept. of Radiat. Oncol., MD Anderson Cancer Center

1

Pb-11

TGF-β-induced Epithelial-Mesenchymal Transition (EMT) is suppressed by heat treatment in
human colon adenocarcinoma cell line
Satoko Adachi, Sotoshi Kokura, Takeshi Ishikawa, Naoyuki Sakamoto, Tetsuya Okayama, Manabu
Okajima, Tatuzo Matsuyama, Reiko Tsuchiya, Yuji Naito, Toshikazu Yoshikawa
Dept. of Molecular Gastroenterology and Hepatology, Kyoto Pref. Univ. of Med.
－ 30 －

Pb-12A role for Ctr1 in the synergistic interaction between hyperthermia and cisplatin
Chelsea D. Landon, Sarah Benjamin, Mark W. Dewhirst

Rad9 and Rad17 are required for heat-induced activation of ATR-Chk1 signaling pathway andheat tolerance

Room A

Munkhbold Tuul1, Hiroyuki Kitao2, Kazuaki Matsuoka2, Makoto Iimori2, Shinichi Kiyonari2,
Hiroshi Saeki1, Eiji Oki1, Masaru Morita1, Yoshihiko Maehara1

29

Pb-13

28

Dept. of Pathology, Duke Univ. Med. Center

Dept. of Surg. and Sci., Kyushu Univ., 2Dept. of Molecular Oncol., Kyushu Univ.

15:15-18:00
Dept. of Internal Med., Higashiyamato Hosp.

Global microRNA expression profiling of human oral squamous cell carcinoma cell lines in
response to hyperthermia
Grad. Sch. of Med. and Pharm. Sci., Univ. of Toyama, 2Grad. Sch. of Med. and Pharm. Sci., Univ.
of Toyama1

Ryo Suzuki, Yusuke Oda, Daiki Omata, Yoshikazu Sawaguchi, Kazuo Maruyama

Low-intensity ultrasound enhances anti-cancer effect of cetuximab on human head and neckcancer cells
Ichiro Ota1, Takashi Masui1, Masatoshi Kanno2, Hiroshi Hosoi1

Moderate heat treatment enhances activities of human cytotoxic T lymphocytes

Pb-18

The enhancement of hyperthermia-induced apoptosis by Shikonin and its underlying molecularmechanism
Jin-Lan Piao1, Zheng-Guo Cui2, Takashi Kondo1
Dept. of Radiological Sci., Grad. Sch. of Med. and Pharm. Sci., Univ. of Toyama, 2Dept. of Public
Health, Grad. Sch. of Med. and Pharm. Sci., Univ. of Toyama
1

Pb-19

Apoptotic cell death by the novel natural compound, cinobufotalin
Heba Emam, Qing-Li Zhao, Takashi Kondo
Dept. of Radiological Sci., Univ. of Toyama－ 31 －

Room B

1st Dept. of Pathology., Sapporo Med. Univ., Sch. Med.

31

Akari Takahashi, Toshihiko Torigoe, Yoshihiko Hirohashi, Yasuaki Tamura, Takayuki Kanaseki,
Noriyuki Sato

Room A

Pb-17

31

Dept. of Otolaryngology-Head and Neck Surg., Nara Med. Univ., 2Cancer Center, Nara Med.
Univ.

1

Room B

Pb-16

30

Lab. of Drug and Gene Delivery, Fac. of Pharma-Sci., Teikyo Univ.

Room A

Enhancement of anti-tumor effect by the combination of ultrasound mediated mild hyperthermia
and immunotherapy

30

Pb-15

Room C

Ayako Kariya1, Yukihiro Furusawa1, Ryohei Ogawa1, Takashi Kondo1, Yoshiaki Tabuchi2

29

Pb-14

Room B

Chairperson: Valentina Ostapenko

29

Poster-Short Oral pr. 03

Room A1

Pb-20

Molecular mechanisms involved in the enhancement of hyperthermia-induced apoptosis bydocosahexaenoic acid, -Implication for cancer therapyZheng-Guo Cui1, Loreto Jr., Bandoy Feril2, Hidekuni Inadera1
Dept. of Public Health, Grad. Sch. of Med. and Pharm. Sci., Univ. of Toyama, 2Dept. of Anatomy,
Fukuoka Univ. Sch. of Med.

1

Poster-Short Oral pr. 04

15:15-18:00
Chairperson: Shin-ichiro Masunaga

Particle Radiat. Oncol. Res. Center, Res. Reactor
Inst., Kyoto Univ.

Pb-21

Treatment enhancement of ultrasound-mediated nanodrug delivery in combination withhyperthermia
Chi-Feng Chiang1, Heng-Ruei Shiu1, Hsiao-Ching Tseng1, Fu-Hsiung Chang2, Win-Li Lin1
Inst. of Biomed. Eng., Nat’l Taiwan Univ., 2Inst. of Biochem. and Molecular Biology, Nat’l Taiwan
Univ.
1

Pb-22

The therapeutic potential of combining OXi4503, radiation and mild temperature hyperthermia
Michael R. Horsman
Dept. Experimental Clinical Oncol., Aarhus Univ. Hosp.

Pb-23

Novel cationic thermosensitive liposomes for targeted and controlled drug delivery to tumor
vasculature and tumor cells
Bilyana M. Dicheva1, Timo LM Ten Hagen1, Li Li1, Debby Schipper1, Ann L.B. Seynhaeve1, Gerard
C van Rhoon5, Alexander MM Eggermont1,2, Lars H Lindner1,3,4, Gerben A Koning1
Dept. of Surgical Oncol., Rotterdam, Erasmus MC, 2Cancer Inst. Gustave Roussy, Paris, 3Dept.
of Internal Med. III,Munich,Ludwig-Maximilians Univ., 4CCG-Hyperthermia, Munich, German
Res. Center for Environmental Health, 5Dept. Radiotherapy, Rotterdam, Erasmus Med. Center
1

Pb-24

Antitumor effects of nano-bubble hydrogen-dissolved water are enhanced by coexistent platinum
colloid and the combined hyperthermia concurrently with Apoptosis -like cell death
Ryoko Asada1, Katsuhiro Kageyama2, Hiroshi Tanaka2, Masanori Takeshita2, Masatsugu Kimura3,
Yasukazu Saitoh4, Nobuhiko Miwa2
Dept. of Radiological Tech., Osaka Butsuryo Coll., 2Fac. of Health Sci., Butsuryo Coll. of Osaka,
Radioisotope Center, Osaka City Univ., 4Fac. of Life and Environmental Sciences, Pref. Univ. of
Hiroshima

1
3

Pb-25

Cancelation of hyperthermia induced reactive oxygen species in rat plasma
Megumi Ueno1, Minako Nyui1, Ikuo Nakanishi1, Kazunori Anzai1,2, Toshihiko Ozawa1,3, Ken-ichiro
Matsumoto1, Yoshihiro Uto4
Res. Center for Charged Particle Therapy, Nat’l Inst. of Radiological Sci., 2Nihon Pharm. Univ.,
Yokohama Coll. of Pharm., 4Inst. of Tech. and Sci., The Univ. of Tokushima

1
3

Pb-26

Screening of phytochemicals sensitizing heat sensitivity of cancer cells
Shin-ichi Bando1, Osamu Hatano2, Hiroshi Takemori3, Nobuo Kubota4, Ken Ohnishi1
Dept. Biol. Ibaraki Pref. Univ. Health Sci., 2Dept. Anat., Nara Med. Univ., 3Natl Inst. Biomed.
Innovat., Lab. Cell Signal. Metabo. Disord., 4Dept. Radiol. Sci., Ibaraki Pref. Univ. Health Sci.

1

－ 32 －

Poster-Short Oral pr. 05

15:15-18:00

A new cancer treatment strategy with magnetic anti-cancer compound with hyperthermia
Xianfeng Feng1, Hidenobu Fukumura1, Itaru Sato1, Haruki Eguchi2, Yoshihiro Ishikawa1

29

Pb-27

Room A

Nat’l Kyushu Cancer Center, Dept. of
Gastroenterological Surg.

Dept. of Cardiovascular Res. Inst., Yokohama City Univ. of Med., 2IHI Co.

1Hyperthermia using magnetic nanoparticles combined with intratumoral dendritic cells enhance
antitumor effectDept. of Radiological Sci. of Toyama Univ., 2Dept. of Cancer Cell Biology, Toyama Univ., 3Dept.
of Div. of Molecular Genetics Res., Toyama Univ., 4Dept. of Low Dose Radiat. Res. Center, Komae,
5Dept. of Div. of Pathogenic Biochem., Toyama Univ.

30

Peng Li1, Yukihiro Furusawa1, Zheng-Li Wei1, Hiroaki Sakurai2, Yoshiaki Tabuchi3, Qing-Li Zhao1,
Takaharu Nomura4, Ikuo Saiki5, Takashi Kondo1

Room C

TAK1 promotes cell survival of HeLa cells exposed to heat stress dependently on TNFAIP3 andIL-8 inductions but independently of NF-κB phosphorylations

29

Pb-29

Room B

Dept. of Oral and Maxillofacial Surg., Nagoya Univ. Grad. Sch. of Med., 2Dept. of Oral andMaxillofacial Surg., Nagoya City Univ. Grad. Sch. of Med. Sci., 3Dept. of Oral and Maxillofacial
Surg., Yokohama City Univ. Grad. Sch. of Med., 4Coll. of Biosci. and Biotech., Chubu Univ.5
129

Noriyuki Yamamoto1, Koushi Matsumoto1, Hiroki Furue1, Sumitaka Hagiwara1, Masaya Nishikawa1,
Hideharu Hibi1, Toshio Shigetomi2, Kenji Mitsudo3, Iwai Tohnai3, Takeshi Kobayashi4, Minoru Ueda1

Room A

Pb-28

28

Chairperson: Yasushi Toh

1Hyperthermia sensitizes resistant human oral cancer cells to IL-13 cytotoxin
Hideyuki Nakashima1,2, Mitomu Kioi1,2, Makiko Sugiura1, Kei Sugiura1, Itaru Sato1, Masaki Iida1,
Kenji Mitsudo1, Syed R Husain2, Raj K Puri2, Iwai Tohnai131

Dept. of Oral and Maxillofacial Surg., Yokohama City Univ. Grad. Sch. of Med., 2Tumor Vaccines
and Biotech. Branch, Div. of Cellular and Gene Therapies, CBER, FDA

Room B1

Pb-32

Controlling gene expression in human prostate cancer cells by ultrasound-responsive promoters
Akihiro Mori1, Ryohei Ogawa2, Akihiki Watanabe1, Takashi Kondo2, Hideki Fuse1
Dept. Urology, Grad Sch. Med. Pharm. Sci., Univ. Toyama, 2Dept. Radiol. Sci., Grad Sch. Med.
Pharmaceut. Sci., Univ. Toyama
1

Pb-33

Room A

Pb-31

31

Dept. of Expt’l Radiol. and Health Phys., Fac. of Med. Sci., Univ. of Fukui, 2The Center for
Urology and Nephrology, Saitamaken-oh Hosp., 3Res. and Development, The Wakasa-wan Energy
Res. Center, 4Dept. of Urology, Kitasato Univ. Sch. of Med.
1

Room B

Sachiko Hayashi1, Ken Koshiba2, Hisaya Shiozaki2, Masanori Hatashita3, Takefumi Sato4, Yutaka
Jujo2, Ryuta Suzuki2

30

Thermosensitization and induction of apoptosis or cell-cycle arrest via the MAPK cascade byparthenolide, an NF-κB inhibitor, in human prostate cancer cell lines

Room A

Pb-30

Hyperthermia regulates HSP expression in human keratinocytes exposed to ultraviolet B
Paras Jawaid1, Yoko Yoshihisa2, Mriame Ali Hassan1, Mati Ur Rehman2, Tadamichi Shimizu2,
Takashi Kondo1
Dept. of Radiological Sci. Toyama Univ., 2Dept. of Dermatology Toyama Univ.

1－ 33 －

Poster-Short Oral pr. 06

15:15-18:00
Chairperson: Akira Mogi

Dept. of General Surgical Sci., Gunma Univ. Grad.
Sch. of Med.

Pb-34

HIFU-based sonodynamic therapy of melanoma cells with verteporfin
Katsuro Tachibana1, Seyedeh M. Nejad1, Reiko Naito3, Hamid R. Hosseini2, Hitomi Endo1, Koichi
Ogawa1, Juichiro Nakayama3
Dept. of Anatomy, Fukuoka Univ. Sch. of Med., 2Bioelectrics Res. Center, Kumamoto Univ.,
Dept. of Dermatology, Fukuoka Univ. Sch. of Med.

1
3

Pb-35

The dual aspects of ATM-Chk2 pathway for the regulation of heat stress induced apoptosis
Takashi Iizumi1, Li Peng1, Yukihiro Furusawa1, Ayako Kariya1, Qing-Li Zhao1, Yoshiaki Tabuchi2,
Takashi Kondo1
Dept. of Radiological Sci., Toyama Univ., 2Div. of Molecular Genetics Res., Life Sci. Res. Center,Toyama Univ.
1

Pb-36

The significance of stress-responsive transcription factors in cancer stem cells
Kazuyo Yasuda, Toshihiko Torigoe, Yoshihiko Hirohashi, Takahumi Kuroda, Akari Takahashi,
Noriyuki SatoFirst Dept. of Pathology Sapporo Med. Univ. Sch. of Med.

Pb-37

Evaluation of ghost cell survival in the area of radiofrequency ablation
Kuansheng Ma, Qi Wang, Jiansheng Huang, Tingjun Li, Feng Xia, Ming Chen, Shuguang Wang,
Ping Bie, Zhenping He
The Inst. of Hepatobiliary Surg., Southwest Hosp., Third Military Med. Univ, Chongqing,
P.R.China

Pb-38

Pentoxifylline enhance the efficacy of thermochemotherapy using thermosensitive liposomes
Kotaro Morita1, Kenichi Kakinuma2, Friedrich Zywietz3, Masashi Kato4
Dept. of Neurosurgery, Tachikawa General Hosp., 2Dept. of Neurosurg, Niigata Rosai Hosp., 3Inst.
of Biophysics and Radiobiology Univ. Hosp. Eppendorf, 4Dept. of Pharm. Niigata Iryo Center

1

Pb-39

Effects of whole-body heat treatment on the function of T cells in human system
Yasunobu Kobayashi1, Yusuke Ito1, Yuri Yoshimoto1, Ayako Suzuki1, Valentina V. Ostapenko1,
Norimasa Matsushita1,3, Kenichiro Imai1,3, Ryuji Okuyama1,3, Koichi Shimizu1,2, Atsushi Aruga1,4,
Keishi Tanigawa1
Bio-Thera Clinic, 2Shin-Itabashi Clinic, 3Inst. of Gastroenterology, Tokyo Women’s Med. Univ.,
Inst. of Advanced Biomed. Eng. and Sci., Tokyo Women’s Med. Univ.

1
4

Pb-40

Bystander effect of oncothermia
Gabor Andocs, Yoshiharu Okamoto, Tomohiro Osaki, Takeshi Tsuka, Tomohiro Imagawa, Saburo
MinamiDept. of Veterinary Clinical Med., Fac. of Agric., Tottori Univ.,－ 34 －

Poster-Short Oral pr. 07

15:15-18:00

Pb-41

High intensity focused ultrasound therapy for metastatic hepatic cancer
Ihl Bohng Choi, Hyun Ho Choi

Tumor response and resection margins of rectal cancer after hyperthermochemoradiation therapy

Pb-43

Yuka Okamoto, Saori Morino-Koga, Tomoaki Koga, Kohei Omachi, Mary Ann Suico, Tsuyoshi
Shuto, Hirofumi Kai

29

Dept. of Molecular Med., Grad. Sch. of Pharm. Sci., Kumamoto Univ.

Room C

Cancer Prevention Using SOARA Therapy: A hot bath whole-body hyperthermia treatment
Tomonobu Fukuda, Chiyoko Nukuzuma, Kazuhiko Atsumi

Pb-45

A comparison of radiofrequency and microwave hyperthermia on knee osteoarthritis

Biodistribution of temperature-sensitive liposomes for MR-image guided drug delivery
Eindhoven Univ. of Tech., Dept. of Biomed. Eng., Eindhoven, the Netherlands, 2Philips Res.
Eindhoven, Dept. of Minimally Invasive Healthcare, Eindhoven, the Netherlands
1Michael Peller1, Martin Hossann2,3, Tungte Wang2,3, Zulfiya Syunyaeva2, Anja Zengerle2, Rolf D.
Issels2,3, Maximilian Reiser1, Lars H. Lindner2,3Inst. for Clinical Radiology, Univ. Hosp. Munich, Ludwig-Maximilians Univ., Munich, 2Dept. ofMed. III, Univ. Hosp. Munich, Ludwig- Maximilians Univ., Munich, Germany, 3CCG Tumor
Therapy through Hyperthermia, Helmholtz Zentrum Muenchen, Germany
1

Pb-48

Comparison of full bath and half bath in bathing style of Japan on induction of HSP 70, NK
cell activity and physical index
Youko Itoh1, Kazuki Torii2, Taichi Ishizawa2, Shingo Yano2
Dept. of Nutrition, Shubun Univ. Fac. of Health and Nutrition, 2Dept. of Products Development,
Bathclin Co., Ltd.

1

－ 35 －

Room B

Comparison of Gd-based contrast agents encapsulated in thermosensitive liposomes for MRI
guided hyperthermia

31

Pb-47

Room A

Mariska de Smet1, Nicole M Hijnen1, Sander Langereis2, Edwin Heijman2, Holger Gruell1,2

31

Pb-46

Room B

Dept. of Orthop., Nippon Med. Sch., 2Hashimoto Clinic, 3Dept. of Radiat. Therapy, Tokyo Kousei
Nenkin Hosp.
1

30

Kenji Takahashi1, Sanshiro Hashimoto2, Hiromasa Kurosaki3, Kenji Takenouchi1, Hiroshi
Nakamura1, Shinro Takai1

Room ATokyo SOARA Clinic

30

Pb-44

Mild electrical stimulation with heat shock (BioMetronome) ameliorates diabetic nephropathy

Room B

Dept. of General Surgical Sci., Gunma Univ., Grad. Sch. of Med., 2Dept. of Radiat. Oncol., Gunma
Univ., Grad. Sch. of Med.
1

29

Soichi Tsutsumi1, Takaaki Fujii1, Hiroki Morita1, Toshinaga Suto1, Jun-ichi Saito2, Takayuki Asao1,
Takashi Nakano2, Hiroyuki Kuwano1

Room A

Pb-42

29

Dept. of Radiat. Oncol., Comprehensive Hosp. for Cancer, Coll. of Med., Catholic Univ.

Room A

Kyoto Coll. of Med. Sci. (Kyoto-MSC)

28

Chairperson: Masashi KawamuraPb-49The use of bath additive (including inorganic salts and carbon dioxide) enhances the inductionof HSP 70, NK cell activity, heat-retaining and improves the physical index
Youko Itoh1, Kazuki Torii2, Taichi Ishizawa2, Shingo Yano2
Dept. of Nutrition, Shubun Univ. Fac. of Health and Nutrition, 2Dept. of Products Development,
Bathclin Co., Ltd

1

Room P

Poster Viewing & Discussion

18:00-19:00－ 36 －

August 29 (Wed.)

Room C

8:40-9:10
Dept. of Radiat. Oncol., Univ.of Tsukuba

Progress in noninvasive MR thermometry

29

ML03

Room A

Chairperson: Hideyuki Sakurai

28

Morning Lecture 3

Dept. of Human and Information Sci., Sch. of Information Sci. and Tech., Tokai Univ., 2Int’l Med.
Device Alliance, Foundation for Int’l Med. Alliance1

Room A

Kagayaki Kuroda1,2

29

9:10-9:40
Chairperson: Takeo Takahashi

The combination therapy of hyperthermia, radiotherapy, and/or chemotherapy in the past,present, and future direction for advanced cervical cancer

30

Yoko Harima

Room C

ML04

29

Dept. of Radiat. Oncol., Saitama Med. Center,
Saitama Med. Univ.

Room B

Morning Lecture 4

Dept. of Radiology, Kansai Med. Univ.

Symposium 5

9:50-11:50

30

9:40-9:50

Room A

Break

Kagayaki Kuroda

S05-1

Paul R. Stauffer1, Paolo F. Maccarini1, Dario B. Rodriques1, Sara Salahi1, Oana I. Craciunescu1,
Yu Yuan2, Shiva K. Das1
1

S05-2

Radiat. Oncol. Dept., Duke Univ., 2Radiat. Oncol. Dept., Univ. of Alabama at Birmingham

Planning guided hyperthermia treatment of head and neck cancer
Margarethus M. Paulides, Zef Rijnen, Jurriaan F. Bakker, Gerda M. van de Velde, Peter C. Levendag,
Gerard C. Van Rhoon
Erasmus MC - Daniel den Hoed Cancer Center－ 37 －

Room B

Towards integration of treatment monitoring with thermal modeling for improved control ofheat treatments

31

Dept. of Human and Information Sci., Sch. ofInformation Sci. and Tech., Tokai Univ.

Room A

Erasmus MC Daniel den Hoed Cancer Center

31

Chairpersons: Gerard C. van Rhoon

Room B

Treatment planning and control of therapy

S05-3Treatment planning specific for interstitial hyperthermia
Yutaka Aoyagi1, Kazuyuki Saito2, Hirotoshi Horita1, Hiroya Ojiri1, Sinji Yamazoe1, Tetuya Simizu1,
Chihiro Kanehira4, Yoshimitu Sunagawa4, Koichi Ito3
Dept. of Radiology Ichikawa, General Hosp., Tokyo Dental Coll., 2Res. Center for Frontier Med.
Eng.,Chiba Univ., 3Grad. Sch. of Eng.,Chiba Univ., 4Dept. of Radiology, Jikei Univ. of Med.

1

S05-4

Theranostic approaches to monitor and control tumor treatment using thermoresponsive nanoliposomes and hyperthermia for triggered drug delivery
Gerben A. Koning
Innovative Targeting Group, Lab. Experimental Surgical Oncol., Dept. of Surg., Erasmus MC

S05-5

Patient-specific treatment planning in hyperthermia, RF and HIFU Ablation
Adamos Kyriakou1, Esra Neufeld2, Niels Kuster1
1

S05-6

IT’IS Foundation/ ETH Zurich, 2IT’IS Foundation

Treatment planning and ultrasound-based temperature monitoring for focused ultrasoundthermal therapy
Hao-Li Liu
Dept. of Electrical Eng., Chang-Gung Univ.

Break

11:50-12:00

Symposium 6

13:00-15:00

Physical medicines with thermal therapy on chronic diseases
Chairpersons: Hirofumi Kai

Dept. of Molecular Med., Kumamoto Univ.

Philp Hooper

Univ. of Colorado Denver, Sch. of Med.

S06-1

Heat shock proteins: Contribution to pathogenesis and treatment of major chronic diseases
Philp Hooper
Univ. of Colorado Denver, Sch. of Med.

S06-2

Mild electrical stimulation and heat shock ameliorates progressive proteinuria and renal
inflammation in mouse model of chronic kidney diseases
Hirofumi Kai, Tomoaki Koga, Yukari Kai, Saori M. Koga, Mary Ann Suico, Tsuyoshi Shuto
Dept. of Molecular Med., Kumamoto Univ.

S06-3

Heat treatment with mild electrical stimulation reduces visceral adiposity and improves insulin
resistance and inflammatory markers in male subjects with type 2 diabetes
Tatsuya Kondo1, Rina Matsuyama1, Katsutoshi Miyagawa1, Rieko Goto1, Hirofumi Kai2, Eiichi
Araki1
Dept. of Metabolic Med., Fac. of Life Sci., Kumamoto Univ., 2Dept. of Molecular Med., Fac. ofLife Sci., Kumamoto Univ.
1－ 38 －

S06-4

Withdrawn

S06-5

The enhancement of chemotherapy, immunotherapy and molecular target teherapy by mildhyperthermia

28

Takeo Hasegawa1, Satoshi Kokura2, Tohru Takahashi3, Tsutomu Takeda4, Itsuo Yamamoto5, Kazuko
Uno1, Kaori Sadamoto1, Iuko Yasuda1, Mari Tanigawa1, Atsuko Kishi1, Toshikazu Yoshikawa2

Room A
29
Room A

Dept. of Basic Res., Louis Pasteur Center for Med. Res., 2Dept. of Molecular Gastroenterology
and Hepatology, Kyoto Pref. Univ. of Med., 3Dept. of Radioisotope Center, Kansai Med. Univ.,
4
Dept. of Surg., Osaka Center Immuno-Chemotherapy Center, 5Dept. of Radio-Frequency Res.
Center, Yamamoto Vinita Co.
1

Break

15:00-15:15

29

Poster-Short Oral pr. 01

15:15-18:00

Room B

Pc-01

Preparation and characterization of Fe3O4 nano particles for cancer hyperthermia
Makoto Takahashi1, Yuki Yogo2, Kaname Tsutsumiuchi3, Takeshi Kobayashi4, Noriyasu Kawai530

Dept. of Applied Chem., Chubu Univ., 2Dept. of Applied Chem., Chubu Univ., 3Dept. of Biological
Chem., Chubu Univ., 4Dept. of Biological Chem., Chubu Univ., 5Dept. of Nephro-Urology, Nagoya
City Univ. Grad. Sch. of Med. Sci.

Room A

1

Compact radiating element for 433 MHz applicator of superficial hyperthermia system
Dept. of Electrical and Electronic Eng., Yonsei Univ.
Intracavitary applicators for thermotherapy
Dept. of EM Field, Fac. of Electrical Eng., Czech Tech. Univ. in Prague, 2Dept. of Med. Devices,Fac. of Biomed. Eng., Czech Tech. Univ. in Prague

1

Heating properties of a new hyperthermia system for non-invasive treatment of deep tumors

Grad. Sch. of Sci. and Tech., Meiji Univ., 2Dept. of Mechanical Eng. Informatics, Meiji Univ., 3The
Future Creation Lab., Olympus Co., LTD., 4Niigata Cancer Center, Section of Neurosurgery
1

Pc-05

Human-tissue-equivalent phantom compatible for hyperthermia and 3.0 T MRI
Hirokazu Kato1, Kengo Hattori2, Yusuke Ikemoto3, Wataru Takao3, Seiichiro Ohno1, Takashi Harimoto1,
Masahiro Kuroda1, Koichi Shibuya1, Masataka Oita1, Nobue Uchida4, Susumu Kanazawa5
Grad. Sch. of Health Sci., Okayama Univ., 2Dept. of Radiology, Nagoya Memorial Hosp., 3Dept.
of Radiology, Okayama Kyokuto Hosp., 4Dept. of Radiology, Tottori Pref. Central Hosp., 5Grad.
Sch. of Med., Dentistry and Pharm. Sci., Okayama Univ.
1－ 39 －

Room B

Kouhei Yokoyama1, Yasuhiro Shindo2, Kazuo Kato2, Mitsunori Kubo3, Takeo Uzuka4, Hideaki
Takahashi4

31

Pc-04

Room AJan Vrba1, Barbora Vrbova1, Jaroslav Vorlicek1, David Vrba2, Jan Vrba Jr.2

31

Pc-03

Room BWoo Cheol Choi, Young Joong Yoon, Ki Joon Kim

30

Pc-02

Room CRadiological Tech., Grad. Sch. of Health Sci.,
Okayama Univ.

29

Chairperson: Masahiro Kuroda

Pc-06

Heating properties of coaxial needle applicator made of shape memory alloy
Tatsuya Yamada1, Yasuhiro Shindo2, Kazuo Kato2, Mitsunori Kubo3, Takeo Uzuka4, Akira
Takeuchi5
Grad. Sch. of Sci. and Tech., Meiji Univ., 2Dept. of Mechanical Eng. Informatics, Meiji Univ.,
3
The Future Creation Lab., Olympus Co., LTD, 4Niigata Cancer Center, Section of Neurosurgery,5
Dept. of Thermotherapy, Luke Clinic
1

Pc-07

Heating performances of circular loop antenna in water for external hyperthermic application
Samon Ishikawa, Kazuyuki Saito, Masaharu Takahashi, Koichi Ito
Chiba Univ.

Pc-08

Simulations and experimental verifications of influence of blod-flow on temperature distribution
during hyperthermia treatment
Jan Vrba1, Tomas Vydra1, Daniel Havelka1, Jan Vrba Jr.2, David Vrba2, Barbora Vrbova1, Jaroslav
Vorlicek1
Dept. of EM Field, Fac. of Electrical Eng., Czech Tech. Univ. in Prague, 2Dept. of Med. Devices
Field, Fac. of Biomed. Eng., Czech Tech. Univ. in Prague

1

Pc-09

Deep local hyperthermia using implantable electrodes and insulation sheets: evaluation of power
absorption uniformity in the heating target organ
Hiroshi Hirayama1, Kenji Shiba2
Applied Electronics, Grad. Sch. of Industrial Sci. and Tech., Tokyo Univ. of Sci., 2Dept. of Applied
Electronics, Fac. of Industrial Sci. and Tech., Tokyo Univ. of Sci.

1

Pc-10

Deep local hyperthermia combined with flexible ribbon-type wireless energy transmission-Analysis of SAR in abdominal regionTakehiro Shibuya1, Kenji Shiba2
Applied Electronics, Grad. Sch. of Industrial Sci. and Tech., Tokyo Univ. of Sci., 2Dept. of Applied
Electronics, Fac. of Industrial Sci. and Tech., Tokyo Univ. of Sci.

1

Pc-11

Fast thermal simulations with realistic 3D vessel networks
Petra Kok1, Nico van den Berg2, Arjan Bel1, Hans Crezee1
Dept. Radiat. Oncol., Academic Med. Center, Univ. of Amsterdam, 2Dept. Radiotherapy, Univ.
Med. Center Utrecht
1

Pc-12

A fast adaptive power scheme based on temperature distribution and convergence value for
optimal hyperthermia treatment
Huang-Wen Huang1, Chi-Feng Chiang2, Win-Li Lin2
Dept. of Innovative Information and Tech., Langyang Campus, Tamkang Univ., 2Inst. of Biomed.
Eng., Nat’l Taiwan Univ., Taipei, Taiwan
1－ 40 －

Poster-Short Oral pr. 02

15:15-18:00

Pc-13

Effective heating for tumors with thermally significant blood vessels during hyperthermia treatment
Huang-Wen Huang1, Chi-Feng Chiang2, Win-Li Lin2

Introduction on coaxial-dipole antenna for generation of controllable heating patterns inlongitudinal direction

Pc-15

Conditions of homogeneous SAR distribution in regional thermotherapy
Barbora Vrbova1, Jan Vrba1, David Vrba2, Jan Vrba Jr.2, Jaroslav Vorlicek1

Design of slot applicator for local thermotherapy
Jaroslav Vorlicek1, Jaroslav Kosik2, Jan Vrba1

Microwave applicators with optimized effective aperture
Dept. of Med. Devices, Fac. of Biomed. Eng., Czech Tech. Univ. in Prague, 2Dept. of EM Field,
Fac. of Electrical Eng., Czech Tech. Univ. in Prague

31

Jan Vrba Jr.1, David Vrba1, Barbora Vrbova2, Jaroslav Vorlicek2, Jan Vrba2

Room A

Pc-18

31

Dept. of EM Field, Fac. of Electrical Eng., Czech Tech. Univ. in Prague, 2Dept. of Med. Devices,Fac. of Biomed. Eng., Czech Tech. Univ. in Prague

1

Room B

Pc-17

30

Dept. of EM Field, Fac. of Electrical Eng., Czech Tech. Univ. in Prague, 2Dept. of Med. Devices
Field, Fac. of Biomed. Eng., Czech Tech. Univ. in Prague

1

Room A

Pc-16

30

Div. of Med. Eng. Res., Nat’l Health Res. Inst., 2Inst. of Biomedicla Eng., Nat’l Taiwan Univ.,
Taipei, Taiwan, 3Dept. of Med. Biotech., Dongguk Univ., Seoul, Korea, 4Dept. of Biomed. Eng.,
Univ. of Southern California, Los Angeles, CA.
1

Room C

Gin-Shin Chen1, Che-Yu Lin2, Jong Seob Jeong3, Jonathan M. Cannata4, Hsu Chang1, K. Kirk
Shung4, Win-Li Lin2

29

Design and characterization of dual-curvature 1.5-dimensional focused ultrasound phased-arraytransducer for tumor thermal therapy

Room B

Grad. Sch. of Eng., Chiba Univ., 2Res. Center for Frontier Med. Eng., Chiba Univ.

1

29

Koichi Ito1, Kazuyuki Saito2, Hiroshi Itakura1, Samon Ishikawa1, Masaharu Takahashi2

Room A

Pc-14

29

Dept. of Innovative Information and Tech., Langyang Campus, Tamkang Univ., 2Inst. of Biomed.
Eng., Nat’l Taiwan Univ., Taipei, Taiwan
1

Room A

Saito Yukoukai Hosp.

28

Chairperson: Hironobu Nakamura

1

Evaluation on heating characteristics of the microwave antenna for tissue coagulation device
Mizuki Inoue1, Kazuyuki Saito2, Masaharu Takahashi2, Koichi Ito1
1

Pc-20

Grad. Sch. of Eng., Chiba Univ., 2Res. Center for Frontier Med. Eng., Chiba Univ.

Adverse effect of radiofrequency capacitive hyperthermia with magnetite on blood vessel walls:
An agar phantom study
Noriyasu Kawai, Taku Naiki, Toshiki Etani, Daichi Kobayashi, Yosuke Ikegami, Ryosuke Ando,
Yoshihiro Hashimoto, Keiichi Tozawa, Kenjiro Kohri
Dept. of Urology, Nagoya City Univ. of Med.
－ 41 －

Room B

Pc-19

Pc-21

In vitro assessment of change of the apparent diffusion coefficient of Jurkat cells after heating
using bio-phantoms and MRI
Masahiro Kuroda1, Kazunori Katashima2, Masakazu Ashida2, Susumu Kanazawa3, Shoji Kawasaki1,
Hirokazu Kato1
Radiological Tech., Grad. Sch. of Health Sci., Okayama Univ., 2Dept. of Oral and Maxillofacial
Radiology, Grad. Sch. of Med., Dentistry and Pharm. Sci., 3Dept. of Radiology, Grad. Sch. of Med.,
Dentistry and Pharm. Sci., Okayama Univ.
1

Pc-22

High-sensitive in vivo detection of oxidative stress with OKD48 transgenic mice
Daisuke Oikawa1,2, Ryoko Akai1,2, Mio Tokuda2, Takao Iwawaki1,2,3
Iwawaki lab, ASRLD Unit, Gunma Univ., 2Iwawaki Initiative Res. Unit, ASI, RIKEN., 3PRESTO,
JST.
1

Pc-23

Three-dimensional cell culture array using magnetic force-based cell patterning for analysis of
the competitive effect of NPrCAP and heat treatments
Hiroyuki Honda1, Syuhei Yamamoto1, Mina Okochi1, Kowichi Jimbow2
Dept. of BioTech., Grad. Sch. of Eng., Nagoya Univ., 2Dept. of Dermatology, Sapporo Med. Univ.
Sch. of Med.

1

Pc-24

Analysis of tumor-infiltrating lymphocytes after hyperthermia using functionalized magnetite
nanoparticles
Masaki Yamaguchi1, Akira Ito1, Noriaki Okamoto1, Yuji Sanematsu1, Yoshinori Kawabe1, Kazumasa
Wakamatsu2, Shosuke Ito2, Hiroyuki Honda3, Takeshi Kobayashi4, Eiichi Nakayama5, Yasuaki
Tamura, Masae Okura7, Toshiharu Yamashita7, Kowichi Jimbow7, and Masamichi Kamihira1
Dept. of Chem. Eng., Fac. of Eng., Kyushu Univ., 2Dept. of Chem., Fujita Health Univ. Sch. of
Health Sci., 3Deprt. of Biotech., Sch. of Eng., Nagoya Univ., 4Sch. of Biosci. and Biotech., Chubu
Univ., 5Fac. of Health and Welfare, Kawasaki Univ. of Med. Welfare, 6First Dept. of Pathology,
Sapporo Med. Univ. Sch. of Med., 7Dept. of Dermatology, Sapporo Med. Univ. Sch. of Med.
1

Pc-25

Synthesis of antibody-conjugating P(VP-MMA-MA)-coated magnetite nanoparticles to target
HER2-overexpressing gastric cancer cells
Kaname Tsutsumiuchi1, Honami Kamiya1, Mina Kondo1, Makoto Takahashi2, Hayao Nakanishi3,
Takeshi Kobayashi1
Coll. of BioSci. and BioTech., Chubu Univ., 2Coll. of Eng., Chubu Univ., 3Div. of Oncological
Pathology, Aichi Cancer Center Res. Inst.

1－ 42 －

Poster-Short Oral pr. 03

15:15-18:00

Pc-26

Assessment of normal tissue temperature rise in magnetic nanoparticle hyperthermia
Alireza Mashal, Martin Huisjen, Dan McKenna

Preparation of nano-sized magnetic Y3Fe5O12 powder by bead milling and its high heat generation
ability in ac magnetic field
Grad. Sch. of Sci. and Eng., Ehime Univ.
Simulation of temperature rise induced by HIFU in tissue mimicking gel considering cavitation
bubbles

Simultaneous generation of multiple cavitation clouds by phased array transducer

Dept. of Electrical and Communication Eng., Tohoku Univ., 2Dept. of Biomed. Eng., Tohoku
Univ.

1

Room A

Kotaro Nakamura1, Ayumu Asai1, Hiroshi Sasaki1, Hiroki Okano1, Shin Yoshizawa1, Shin-ichiro
Umemura1,2

30

Pc-29

Room C

Dept. of Electrical and Communication Eng., Tohoku Univ., 2Dept. of Biomed. Eng., Tohoku
Univ.

1

29

Ayumu Asai1, Hiroki Okano1, Shin Yoshizawa1, Shin-ichiro Umemura1,2

Room B

Pc-28

29

Hiromichi Aono, Tadahiko Nishimori

Room A

Pc-27

29

Actium Biosystems

Room A

Dept. of Thermotherapy, Luke Clinic

28

Chairperson: Akira Takeuchi

30

Quantitative 3D-reconstruction of high intensity focused ultrasound pressure field from opticalmeasurement
Soichiro Harigane1, Ryo Miyasaka1, Shin Yoshizawa1, Shin-ichiro Umemura1,2

Optimization of HIFU treatment by focus steering

Dept. of Mechanical Eng., The Univ. of Tokyo, 2Nat’l Inst. of Advanced Industrial Sci. and Tech.,3
Dept. of Mechanical Eng., Coll. of Industrial Tech., Nihon Univ.

31

Kosuke Matsuki1, Ryuta Narumi1, Takashi Azuma1, Kiyoshi Yoshinaka2, Akira Sasaki1, Kohei
Okita3, Shu Takagi1, Yoichiro Matsumoto1

Room A

Pc-31

31

Dept. of Electrical and Communication Eng., Tohoku Univ., 2Dept. of Biomed. Eng., Tohoku
Univ.

1

Room B

Pc-30

1

Three-Dimensional vessel tracking for liver HIFU using stereoscopic MR imaging
Etsuko Kumamoto 1,2, Shunpei Iwaoka 2, Daisuke Kokuryo 3, Toshiya Kaihara 2, Kagayaki
Kuroda4,5
Information Tech. and Sci. Center, Kobe Univ., 2Grad. Sch. of System Informatics, Kobe Univ.,
3
Molecular Imaging Center, Nat’l Inst. of Radiological Sci., 4Grad. Sch. of Eng., Tokai Univ., 5Int’lMed. Device Alliance, Foundation for Int’l Med. Alliance
1

Pc-33

Numerical modeling of HIFU ablation of solid malignancies
Adamos Kyriakou1, Esra Neufeld2, Niels Kuster1
1

IT’IS Foundation/ ETH Zurich, 2IT’IS Foundation－ 43 －

Room B

Pc-32

Pc-34Development of disposable perfusion system for chemo hyperthermic peritoneal perfusion andour use experiences
Mitsuhiro Morikawa, Kanji Katayama, Makoto Murakami, Daisuke Fujimoto, Katsuji Sawai, Kenji
Koneri, Yasuo Hirono, Takanori Goi, Atsushi Iida, Akio Yamaguchi
First Dept. of Surg., Univ. of Fukui

Pc-35

MRI-compatible ring-typed ultrasound phased-array transducer for breast tumor thermal
therapy
Bo-Sian Lin1, Pi-Hsien Lien1, Gin-Shin Chen2, San-Chao Hwang2, Sheng-Fu Chen2, Yung-Yaw
Chen3, Win-Li Lin1,2
Inst. of Biomed. Eng., Nat’l Taiwan Univ., Taipei, Taiwan, 2Div. of Med. Eng. Res., Nat’l HealthRes. Inst.s, Zhunan, Taiwan, 3Dept. of Electrical Eng., Nat’l Taiwan Univ., Taipei, Taiwan

1

Poster-Short Oral pr. 04

15:15-18:00
Chairperson: Keishi Tanigawa
Bio-thera Clinic

Pc-36

Wideband conformal metamaterial antennas for phased array heating of adult bladderTiago R. Oliveira1,4, Sara Salahi2, Gerard Aknine3, M. Teresa Lamy1, Paolo F. Maccarini4, Paul R.
Stauffer4
Instituto de Fisica, Universidade de Sao Paulo, 2Biomed. Eng., Duke Univ., Durham, NC,
BioThermatics, Inc, Franklin, TN, 4Dept. of Radiat. Oncol., Duke Univ., Durham, NC

1
3

Pc-37

Heating characteristics of metallic stent fed by endoscopic coaxial probe for microwave thermal
therapy for bile duct carcinoma
Hiroshi Itakura1, Kazuyuki Saito2, Masaharu Takahashi2, Koichi Ito1
Grad. Sch. of Eng., Chiba Univ., 2Res. Center for Frontier Med. Eng., Chiba Univ.

1

Pc-38

Reduction of heat sensation of a patient using the silicone gel
Daisuke Kobayashi1, Tomonori Isobe2, Kenta Takada2, Keiji Suzuki1, Koichi Shida1, Masashi Seki1,
Hiroshi Yokota1, Takeji Sakae2, Hideyuki Sakurai2
Dept. of Radiology, Tsukuba Univ. Hosp., 2Grad. Sch. of Comprehensive Human Sci., Univ. of
Tsukuba1

Pc-39

Hybrid head and neck hyperthermia and 7T MR imaging: a pilot study
Rene Verhaart1, J.J Bluemink2, J.F. Bakker1, P. Togni1, A.J.E. Raaijmakers2, G.C. van Rhoon1,
C.A.T. van den Berg2, M.M. Paulides1
Dept. of Radiotherapy, Hyperthermia Unit, Erasmus MC Rotterdam, the Netherlands, 2Dept. ofRadiotherapy, Univ. Med. Center Utrecht, the Netherlands
1

Pc-40

Foresight of hyperthermia
Kimiko Yoshimizu1, Itsuo Yamamoto2, Emi Takayama3, Tohru Takahashi4, Takeo Hasegawa5
Garden Clinic Nakamachi, 2Yamamoto Vinita Co., Ltd, 3Aman Co., Ltd., 4Kansai Med. Univ.,
Louis Pasteur Center for Med. Res.

1
5

－ 44 －

Pc-41The optimal heating method for superficial tumors

Grad. Sch. of Comprehensive Human Sci., Univ. of Tsukuba, 2Dept. of Radiology, Tsukuba Univ.
Hosp.

28

Kenta Takada1, Tomonori Isobe1, Daisuke Kobayashi2, Yutaro Mori1, Keiji Suzuki2, Koichi Shida2,
Yousuke Yoshimura1, Masashi Seki2, Hiroshi Yokota2, Hideyuki Sakurai1, Takeji Sakae1
1

Room A

Tzyy-Leng Horng
Dept. of Applied Math., Feng Chia Univ.
Clinical benefit of replacing the sigma 60 by the sigma eye applicator: A Monte Carlo based
uncertainty analysis

Room B

Richard A M Canters, Maarten M Paulides, Gerard C Van Rhoon
Erasmus MC - Daniel den Hoed, Dept. of Radiat. Oncol., Rotterdam, the Netherlands
Towards improved hyperthermia treatment planning (HTP) based on MRI data acquisition

Optimization of the electromagnetic performance of the HyperCollar redesign
Paolo Togni, Zef Rijnen, Roel Roskam, Gerard C. Van Rhoon, Margarethus M. Paulides

Frequency dependent focusing with UWB hyperthermia applicator for H&N cancer
treatment
Hana Dobsicek Trefna, Johanna Gellermann, Mikael Persson

31

Dept. Signals and systems, Chalmers Univ. of Tech.
Double 434MHz hyperthermia unit designed for single and multiple large superficial and semideep tumor lesions

Room A

Pier F. Pavoni1, Paolo Pacetti1, Luigi Dicarlo1, Francesca Cappelli1, Federica Fedeli1, Hans Crezee2,
Paul j Z.V. Sive Vording2, Amalia Di Dia3, Rocco Panaia3, Pietro Gabriele3

31

Pc-47

Room B

Pc-46

30

Dept. Radiotherapy -Hyperthermia unit, Erasmus MC, Rotterdam

Room A

Pc-45

30

Radiotherapy, Academic Med. Center, Amsterdam, Netherlands, 2Radiotherapy, Univ. Med. CenterUtrecht, Utrecht, Netherlands, 3Radiology, Academic Med. Center, Amsterdam, Netherlands
1

Room C

Edmond Balidemaj1, Cornelis A.T. van den Berg2, Aart Nederveen3, Astrid van Lier2, Petra Kok1,
Hans Crezee1

29

Pc-44

29

Pc-43

29

Numerical analysis of coupled effects of pulsatile blood flow and thermal relaxation time during
thermal therapy

Room A

Pc-42

RESTEK Rome, Italy, 2AMC Amsterdam, Nederland, 3IRCC Candiolo (TO), Italy

Room B

1

Room P

Poster Viewing & Discussion

18:00-19:00－ 45 －

August 30 (Thu.)

Room A

Morning Lecture 5

8:40-9:10
Chairperson: Hiroshi Maezawa

The Univ.of Tokushima Grad. Sch., Dept. ofRadiological Sci.

ML05

Detection and clinical application of novel stress biomarkers in peripheral blood
Kazuhito Rokutan
Dept. of Stress Sci., Inst. of Health Biosci., Tokushima Univ. Grad. Sch.

Morning Lecture 6

9:10-9:40
Chairperson: Koji Ono

Kyoto Univ.Res. Reactor Inst., Director of Radiat.
Oncol. Res. Center

ML06

Thermochemistry: A multifaceted energy source for ablation
Erik Cressman
Dept. of Radiol Univ. of Minnesota Med. Center

Break

9:40-9:50

Symposium 7

9:50-11:50

State of the art in clinical heating and prospective heating technologies
Chairpersons: Paul R. Stauffer

Radiat. Oncol. Dept., Duke Univ.

Youji Kotsuka

Tokai Univ.

S07-1

Microwave heating by thin coaxial antennas-Application to interstitial and intracavitary hyperthermiaKazuyuki Saito1, Masaharu Takahashi1, Koichi Ito2
1

S07-2

Res. Center for Frontier Med. Eng., Chiba Univ., 2Grad. Sch. of Eng., Chiba Univ.

Catheter-based ultrasound thermal therapy integrated with Image-Guided HDR brachytherapy
for treatment of locally advanced or recurrent pelvic disease
Chris J. Diederich, Jeff H Wootton, Vasant Salgaonkar, Punit Prakash, Titania Juang, Serena Scott,Richard Cam, Xin Chen, I.C. Joe Hsu
Radiat. Oncol., Univ. of California-San Francisco－ 46 －

S07-3

Conformal microwave applicator using patch antennas for chestwall recurrence of breast
cancerKavitha Arunachalam1, Paolo F Maccarini2, Oana I Craciunescu2, Titania Juang2, Daniel Neuman3,
Francesca Rossetto3, Vinicio Manfrini3, Chris Diederich3, Jaime L Schlorff4, Paul R Stauffer228

Dept. of Eng. Design, Indian Inst. of Tech. Madras, India, 2Dept. of Radiat. Oncol., Duke Univ.
Med. Center, USA, 3Dept. of Radiat. Oncol., Univ. of San Francisco, USA, 4Bionix Development
Co., Paoli, Pennsylvania USA

Room A

1

29

Takayuki Ohguri1, Motohiro Murakami2, Katsuya Yahara1, Hajime Imada2,3, Yukunori Korogi1
Dept. of Radiology, Univ. of Occupational and Environmental Health, 2Dept. of Med. Electronics,
Univ. of Occupational and Environmental Health, 3Dept. of Cancer Therapy Center, Tobata Kyoritsu
Hosp.

Room B

Locoregional heat delivery using capacitively coupled heating method: Usefulness of an insulator
sheet for optimization of deep heating area

29

S07-5

Room A

S07-4

1

Room A

Dept. of Radiat. Oncol., Academic Med. Center/ Univ. of Amsterdam

30

Hans Crezee, Petra Kok, Gerard van Stam, Paul Zum Vorde Sive Vording, Arjan Bel, Jan Sijbrands,
Edmond Balidemaj, Maarten Hulshof

Room C

Locoregional heat delivery using phased array hyperthermia systems

29

S07-6

Break

11:50-12:00

30

Luncheon Seminar 2

12:00-13:00

Room B
31

Chairperson: Tohru Tani

LS2

Hideto Fujita, Takashi Fujimura, Tetsuo Ohta
Sponsored by Yakult Honsha Co., Ltd.

－ 47 －

Room B

Dept. of Gastroenterological Surg., Kanazawa Univ. Hosp.

31

Perioperative chemotherapy for curative treatment of colon cancer : XELOX/FOLFOX therapy
as a second scalpel

Room A

Dept. of Surg., Shiga Univ. of Med. Sci.

Symposium 8

13:00-15:00

Hyperthermia and immunotherapy
Chairpersons: Milton B. Yatvin

Biology Dept., Reed Coll.

Sharon S. Evans

Dept. of Immunology, Roswell Park Cancer Inst.

S08-1

Activation and inhibition of gamma delta T cell mediated anti tumor immunity by heat shockproteins
Shubhada V Chiplunkar
Chiplunkar Lab, ACTREC, Tata Memorial Center, Kharghar, Navi Mumbai

S08-2

The scientific rationale for treating immunologically competent patients with high level wholebody hyperthermia
Milton B. Yatvin1,3, George Ivanov2, Alexei Suvernev2,3Biology Dept., Reed Coll., 2Inst. Siberian Sci. Res. Institution of Hyperthermia, 3Institution Heatheal

1

S08-3

Hyperthermia enhances immunotherapy in cancer patients: 1466 clinical cases
Tsutomu Takeda1, Tohru Takahashi2, Takashi Takeda1, Hiroko Takeda1
Osaka Cancer Immuno-chemotherapy Center, Kyohrinkai, 2RI Center, Kansai Med. Univ.

1

S08-4

Effects of hyperthermia in combination with NK cell based-immune cell therapy on cancer
patients
Hiroshi Terunuma1,2,3, Noriyuki Nishino2, Xuewen Deng3, Akiko Yoshimura1, Yoshinao Takano2,
Atsushi Toki1, Tatsuaki Ishiguro1, Mie Nieda3, Jin-ichi Sasanuma1, Yasushi Teranishi2, Kazuo
Watanabe1,2
1

S08-5

Tokyo Clinic, 2Southern Tohoku General Hosp., 3Biotherapy Inst. of Japan

Hyperthermic targeting of the immune microenvironment for improved cancer immunotherapy
Sharon S. Evans
Dept. of Immunology, Roswell Park Cancer Inst.

Banquet18:40-21:00－ 48 －

August 30 (Thu.)

Room B

8:40-9:10

ML07

Mark Dewhirst

9:10-9:40

ML08

Role of thermal therapy in regulation of bone marrow homeostasis and immune function
following radiation: New clinical opportunities?

Room C

Osaka Cancer Immuno-Chemotherapy Center,
Kyohrinkai

29

Chairperson: Tsutomu Takeda

Room B

Morning Lecture 8

29

Dept. of Radiat. Oncol., Duke Univ. Med. Center, Durham, NC

Room A

New paradigms for targeted drug delivery using thermolabile drug delivery systems:
A bench to bedside journey29

Dept. of Radiat. Oncol., Univ.of Minnesota Med.
Sch.

Room A

Chairperson: Chung K. Lee

28

Morning Lecture 7

30

Elizabeth A. Repasky

Room A

Dept. of Immunology, Roswell Park Cancer Inst.

Break

9:40-9:50

30

Symposium 9

9:50-11:50

Room B
31

Cell signaling and damage response
Oral Radiat. Oncol., Grad. Sch. of Med. and Dental
Sci., Tokyo Med. and Dental Univ.

Hyperthermia activates both ATM and ATR signaling pathways for cell tolerance against
heat
Hiroyuki Kitao1, Tuul Munkhbold1,2, Makoto Iimori1, Kazuaki Matsuoka1, Shinichi Kiyonari1,
Hiroshi Saeki2, Eiji Oki2, Masaru Morita2, Yoshihiko Maehara2
Dept. of Molecular Oncol., Grad. Sch. Med. Sci., Kyushu Univ., 2Dept. of Surg. and Sci., Grad.
Sch. Med. Sci., Kyushu Univ.

1

S09-2

ATM is the predominant kinase involved in the phosphorylation of histone H2AX after heating
Akihisa Takahashi1, Eichiro Mori2,3, David J. Chen3, Takeo Ohnishi2
ASRLD Unit, Gunma Univ., 2Dept. of Radiat. Oncol., Nara Med. Univ., 3Div. of Mol. Radiat.
Biol., Dept. of Radiat. Oncol., UT Southwestern Med. Center1－ 49 －

Room B

S09-1

31

Hiroyuki Kitao

Dept. of Molecular Oncol., Grad. Sch. Med. Sci.,
Kyushu Univ.

Room A

Chairpersons: Masahiko MiuraS09-3Stress-Induced, NO-mediated bystander responses for protecting cells themselves
Hideki Matsumoto
Div. of Oncol., Biomed. Imaging Res. Center, Univ. of Fukui

S09-4

Global expression profiling of genes induced by heat stress
Yoshiaki Tabuchi1, Yukihiro Furusawa2, Kenzo Ohtsuka3, Takashi Kondo2
Life Sci. Res. Ctr., Univ. of Toyama, 2Grad. Sch. of Med. and Pharm. Sci., Univ. of Toyama, 3Dept.
of Environmental Biol., Chubu Univ.

1

S09-5

Role of AMPK/mTOR signaling pathway in the response of cancer cells and cancer stem cells
to hyperthermia
Chang W. Song1, Troy A. Dos Santos1, Hyemi Lee2, Eun J. Kim2, Heon J. Park1,2
Dept. of Radiat. Oncol., Univ. of Minnesota, 2Dept. of Microbiology, Coll. of Med., Inha Univ.,
Inchon, Korea
1

S09-6

The protective effect of mild heat preconditioning at 40C involves the ER stress response
Diana A. Averill-Bates, Pragathi Pallepati
Dept. des Sci. biologiques, Universite du Quebec a Montreal

S09-7

NADPH oxidase-mediated reactive oxygen species production activates hypoxia-inducible
factor-1 (HIF-1) via the ERK pathway after hyperthermia treatment
Mark W. Dewhirst1, Ejung Moon2
Radiat. Oncol. Dept., Duke Univ., 2Radiat. Oncol. Dept., Stanford Univ.

1

Break

11:50-12:00

Symposium 10 (ICHO-BSSR* joint symposium)

13:00-15:00

ICHO-BSSR joint symposium: Heat shock factors, heat shock proteins andcancerChairpersons: Len Neckers

Urologic Oncol. Branch, Center for Cancer Res.,
Nat’l Cancer Inst.

Toshihiko Torigoe

Dept. of Pathology, Sapporo Med. Univ. Sch. of
Med.

S10-1

Heat shock factors and cancer
Akira Nakai
Dept. of Biochem. and Molecular Biology, Yamaguchi Univ. Sch. of Med.

S10-2

Stress response genes are molecular targets of cancer stem cells
Toshihiko Torigoe1, Kazuyo Yasuda1, Yoshihiko Hirohashi1, Satoshi Nishizawa2, Akari Takahashi1,
Yasuaki Tamura1, Isao Hara2, Noriyuki Sato1
Dept. of Pathology, Sapporo Med. Univ. Sch. of Med., 2Dept. of Urology, Wakayama Med.
Univ.

1

－ 50 －

S10-3Control of Cdc37/Hsp90 and kinase signaling in prostate cancer by scan domain proteins
Takanori Eguchi, Thomas L Prince, Ayesha Murshid, Stuart K Calderwood

Phosphorylation of a conserved tyrosine residue in the Hsp90 N-domain determines cancer
sensitivity to Hsp90 inhibition in vitro and in vivo

29

Len Neckers
Urologic Oncol. Branch, Center for Cancer Res., Nat’l Cancer Inst.
Hsp90 and the tumor microenvironment

Room B

Med. Oncol. Branch, Center for Cancer Res., NCI

29

Jane B. Trepel, Sylvia V. Alarcon, Min-Jung Lee, Tomohiro Kajiguch, Sunmi Lee, Wanping Xu,
Fumitaka Koga, Shinji Tsutsumi, Mehdi Mollapour, Akihiro Yano, Len Neckers

Room A

S10-5

Room A

S10-4

28

Dept. of Radiat. Oncol., BIDMC, Harvard Med. Sch.

Poster-Short Oral pr. 01:Japanese

15:15-16:45

30

Chairperson: Yoshio Tamaki

Room C

15:00-15:15

29

Break

Dept. of Radiat. Oncol., Gunma Pref. Cancer Center

Mild electrical stimulation with heat shock ameliorates proteinuria and nephritis in mousemodel of X-linked alport syndrome

Room A

Yukari Kai1, Tomoaki Koga2, Ryosuke Fukuda1, Saori Morino-Koga3, Mary A. Suico1, Kosuke
Koyama1, Tsuyoshi Shuto1, Hirofumi Kai130

Dept. of Molecular Med., Grad. Sch. of Pharm. Sci., Kumamoto Univ., 2Dept. of Med. Biochem., Grad.
Sch. of Med. Sci., Kyushu Univ., 3Dept. of Dermatology, Grad. Sch. of Med. Sci., Kyushu Univ.

Room B

Mild electrical stimulation suppresses fat accumulation and increases stress resistance via
activation of LKB1-AMPK signaling in C. elegans

31

Shingo Matsuyama, Shuichiro Yano, Saori Morino-Koga, Yuka Okamoto, Ihori Shitanda, Kohei
Omachi, Masataka Moriuchi, Mary Ann Suico, Tsuyoshi Shuto, Hirofumi Kai

Room A

Pj-01

1

Pj-02

Mild electrical stimulation suppresses pro-inflammatory cytokines expression via inhibition ofmultiple signaling pathways
Ihori Shitanda, Yuichiro Shimauchi, Saori Morino-Koga, Shuichiro Yano, Tomoaki Koga, Shingo
Matsuyama, Mary A Suico, Tsuyoshi Shuto, Hirofumi Kai
Dept. of Molecular Med., Grad. Sch. of Pharm. Sci., Kumamoto Univ.

Pj-04

Specified pulse-width mild electrical stimulation induces p53 phosphorylation and transcriptional
activation
Ryosuke Fukuda, Kosuke Koyama, Kohei Omachi, Yukari Kai, Shingo Matsuyama, Yuka Okamoto,
Mary A Suico, Tsuyoshi Shuto, Hirofumi Kai
Dept. of Molecular Med., Grad. Sch. of Pharm. Sci., Kumamoto Univ.
－ 51 －

Room B

Pj-03

31

Dept. of Molecular Med., Grad. Sch. of Pharm. Sci., Kumamoto Univ.

Pj-05

Effects of hyperthermia combined with siRNA targeted for HSF1 and/or low dose chemotherapy
in HSC3 cells
Shigehito Wada1, Yoshiaki Tabuchi2, Ayako Kariya3, Takashi Kondo3
Dept. of Oral Surg., Univ. of Toyama, 2Div. of Molecular Genetics Res., Life Sci. Res. Center, Univ.
of Toyama, 3Deprt of Radiological Sci., Grad. Sch. of Med. and Pharm. Sci., Univ. of Toyama

1

Pj-06

Involvement of Hsp90 in epstein-barr virus lytic replication
Daisuke Kawashima, Tatsuya Tsurumi
Div. of Virology, Aichi Cancer Center Res. Inst.

Pj-07

Development of heat ablation area measuring system based on amplitude modulated acoustic
radiation force
Hirofumi Nakamura1, Ryosuke Aoyagi1, Wataru Baba1, Takashi Azuma1, Keisuke Fujiwara3, Hideki
Takeuchi 3, Kazunori Itani 3, Kiyoshi Yoshinaka 2, Akira Sasaki 1, Shu Takagi 1, Yoichiro
Matsumoto1
Dept. of Mechanical Eng., The Univ. of Tokyo, 2Dept. of Human Life Tech., Advanced Industrial
Sci. and Tech., 3Hitachi-Aloka Med.
1

Pj-08

HIFU oral squamous cell carcinoma killing with TiO2
Hiromasa Takahashi1, Seyedeh Moosavi Nejad2, S. Hamid R. Hosseini3, Taishi Otani1, Eiko Higashi2,
Hitomi Endo2, Loreto B. Feril Jr.2, Katsuyuki Nakano4, Toshihiro Kikuta1, Katsuro Tachibana2
Dept. of Oral and Maxillofacial Surg., Fac. of Med, Fukuoka Univ., 2Dept. of Anatomy, Fukuoka
Univ. Sch. of Med., 3Bioelectrics Res. Center, Kumamoto Univ., 4Dept. of Chem. Eng., Fac. of
Tech., Fukuoka Univ.
1

Pj-09

Hyperthermia using implant of resonant circuit delivered through 18G-needle
Kazuya Kumagai1, Kazuhiko Watabe1, Ryo Matsumura1, Tsutomu Yamada1, Kyohei Kezuka1,2,
Reiko Kurotani3, Iwai Tohnai2, Yoshihiro Ishikawa2, Yasushi Takemura1
Dept. of Erectronics and Information Tech., Yokohama Nat’l Univ., 2Dept. of Med., Yokohama
City Univ., 3Dept. of Sci. and Eng.,Yamagata Univ.

1

Poster-Short Oral pr. 02:Japanese

15:15-16:45

Chairperson: Koh Tsuji

Nat’l Hosp. Org. Minami Wakayama Med. Center,
Dept. of Radiology

Pj-10

The efficacy of a catheter filled with a xylocaine jelly to eliminate the disturbance in themeasurement of temperature by thermocouples in the presence of radiofrequency current
Motohiro Murakami1, Takayuki Ohguri2, Katsuya Yahara2, Miyuki Hanada3, Sanae Matsuoka3
Dept. of Med. Electronics, Univ. of Occupational and and Environmental Health, 2Dept. ofRadiology, Univ. of Occupational and and Environmental Health, 3Nursing Dept., Univ. of
Occupational and and Environmental Health

1

Pj-11

For making the hyperthermia treatment widely known in a hospital
Yumiko Kawasaki1, Hideyuki Morosasa1, Yoshiki Miya1, Akihiro Endoh1, Yoshihiko Furuta1,
Takayuki Shishido2, Eiri Ezoe2, Yoshiyuki Yanai2, Rika Fukui2, Takahiro Yasoshima2
Section of clinical Eng., Shinsapporo Keiaikai Hosp., 2Dept. of Surg., Shinsapporo Keiaikai Hosp.

1－ 52 －

Pj-12Three cases of avascular osteonecrosis after hyperthermia

1

Dept. of General Surgical Sci., Gunma Univ. Grad. Sch. of Med.
Regional collaborative clinical pathway of hyperthermo-chemoradiotherapy for locally advanced
rectal cancer

Room B

Hidaka Hosp., Oncol. Center, 2Dept. of Radiat. Oncol., Gunma Univ. Grad. Sch. of Med., 3Dept.
of General Surgical Sci., Gunma Univ. Grad. Sch. of Med., 4Dept. of Radiat. Oncol., Saitama Med.
Center, Saitama Med. Univ.

29

Dept. of Surg., Shinsapporo Keiaikai Hosp., 2Section of Clinical Eng., Shinsapporo Keiaikai
Hosp., 3First Dept. of Pathology, Sapporo Med. Univ. Sch. of Med.
1

Room A

Rika Fukui1, Yoshiyuki Yanai1, Takahiro Yasoshima1, Eiri Ezoe1, Takayuki Shishido1, Hideyuki
Morosawa2, Yoshiki Miya2, Yoshihiko Furuta2, Yasuaki Tamura3

31

The effect and benefit of the hyperthermia therapy combined with low dose chemotherapy and/or hormonal therapy on liver metastasis of breast cancer patients

Room B

Pj-16

30

Hidaka Hosp., Oncol. Center, 2Dept. of Radiat. Oncol., Gunma Univ. Grad. Sch. of Med., 3Dept.
of General Surgical Sci., Gunma Univ. Grad. Sch. of Med., 4Dept. of Radiat. Oncol., Saitama Med.
Center, Saitama Med. Univ.
1

Room A

Kazuki Jinbo1, Koji Sugawara1, Atsushi Okazaki1, Satoshi Suda1, Noriyuki Okonogi1, Masahiko
Motegi1, Takayuki Asao3, Takeo Takahashi4, Takashi Nakano2, Hiroyuki Kuwano3, Yoshitaka
Ando1

30

Preliminary report of preoperative hyperthermo-chemoradiotherapy (HCR) using IMRT for
locally advanced rectal cancer in the regional collaborative HCR treatment and care

Room C

Satoshi Suda1, Kouji Sugawara1, Atsushi Okazaki1, Kazuki Jinbo1, Noriyuki Okonogi1, Masahiko
Motegi1, Takayuki Asao3, Takeo Takahashi4, Takashi Nakano2, Hiroyuki Kuwano3, Yoshitaka
Ando1
1

Pj-15

29

Pj-14

Room A

Atsushi Ogawa, Erito Mochiki, Mitsuhiro Yanai, Kyoichi Ogata, Tetsuro Ohno, Takayuki Asao,
Hiroyuki Kuwano

29

Postoperative intraperitoneal hyperthermochemotherapy by radiofrequency capacitive heating
system for advanced gastric cancer with peritoneal seeding

Room A

Pj-13

Dept. of Orthop. Surg., Nagoya City Univ., 2Dept. of Orthop. Surg., Kanazawa Univ.

28

Satoshi Yamada1, Atsunori Murase1, Katuhiro Hayasi2, Hiroyuki Inatani2, Hideki Okamoto1,
Takanobu Otsuka1

31

Usefulness of upright sitting position with thermotron-RF8;How to
Koji Oki, Atsushi Hori, Masahiko Maeda, Masako Uehara
Rinku-Dejima-Clinic

Pj-18

Usefulness of up-right sitting position with thermotron-RF8; case reports
Atsushi Hori, Masahiko Maeda, Kouji Ooki
Rinku-Dejima-Clinic－ 53 －

Room B

Pj-17

Poster-Short Oral pr. 03:Japanese

15:15-16:45

Chairperson: Atsushi Toki

Tamananbu Chi-iki Hosp. Internalmedicine,
Respiratory

Pj-19

Change of QOL for patients getting long-term hyperthermia treatment
Hideyuki Morosasa1, Yoshiki Miya1, Akihiro Endoh1, Yumiko Kawasaki1, Yoshihiko Furuta1,
Takayuki Shishido2, Eiri Ezoe2, Yoshiyuki Yanai2, Rika Fukui2, Takahiro Yasoshima2
Section of Clinical Eng., Shinsapporo Keiaikai Hosp., 2Dept. of Surg., Shinsapporo Keiaikai
Hosp.
1

Pj-20

Effect of thermosensitization with parthenolide in thermotherapy of localized prostate cancer
combined with androgen deprivation
Ryuta Suzuki1, Ken Koshiba1, Yutaka Jujo1, Kazue Kitahiro1, Hisaya Shiozaki1, Yusuke Sasai1,
Masahiro Aihara2, Sachiko Hayashi3, Nasanori Hatashita4
Center for Urology and Nephrology, Saitama Ken-oh Hosp., 2Kurihama Urology Clinic, 3Dept.
of Experimental Radiology and Health Physics, Fac. of Med., Univ. of Fukui, 4Res. and Development,
The Wakasa-wan Energy Res. Center, Tsuruga, Fukui
1

Pj-21

The relation between the power range of hyperthermia and clinical outcome: Retrospective
study in patients who received regional hyperthermia
Tomokuni Kuwata1, Satoshi Kokura2, Naoyuki Sakamoto1, Takeshi Ishikawa2, Tetsuya Okayama2,
Mari Tanigawa1, Naomi Fujinaka1, Masato Hori1, Toshiro Kimura1, Toshikazu Yoshikawa3
Iseikai Hyakumanben Clinic, 2Molecular Gastroenterology and Hepatology, Grad. Sch. of Med.
Sci., Kyoto Pref. Univ. of Med., 3Kyoto Pref. Univ. of Med.

1

Pj-22

Assessments of quality of life contribute to risk management of patients who received weekly
hyperthermia
Naoko Kitada1, Satoshi Kokura2, Naoyuki Sakamoto1, Takeshi Ishikawa2, Keiko Yamanaka1, Mio
Iefuji 1, Masayo Kogiso 1, Rumiko Okuno 1, Yoko Hoshi 1, Yasuko Nabekura 1, Toshikazu
Yoshikawa3
Iseikai Hyakumanben Clinic, 2Molecular Gastroenterology and Hepatology, Grad. Sch. of Med.
Sci., Kyoto Pref. Univ. of Med., 3Kyoto Pref. Univ. of Med.
1

Pj-23

Immunological examination of synovial fluid in osteoarthritis: Comparison between before andafter hyperthermia treatment
Hiromasa Kurosaki1, Teruaki Sekine2, Kenji Takahashi3
Dept. of Radiat. Oncol., Tokyo Kousei Nenkin Hosp., 2Lymhotec, Inc, 3Deprt. of Orthop. andRheumatology, Nippon Med. Sch.

1

Pj-24

Retrospective analysis of hyperthermia therapy for unresectable pancreatic cancer
Yoshiyuki Yanai, Takahiro Yasoshima, Rika Fukui, Takayuki Shishido, Eiri Ezoe, Yoshihiro
Nakakubo, Katsuyuki Aketa, Kenji Kiriyama, Hideyuki Morosawa, Yoshiki Miya, Yoshihiko
FurutaShinsapporo Keiaikai Hosp.

－ 54 －

Pj-25Adoption of low-temperature ablation (high temperature-hyperthermia) treatment to the clinicalveterinary medicine
28

Shinichi Nakazumi, Yasuaki Munekata

Pj-26

Saitamaken-oh Hosp., 2Dept. of Experimental Radiology and Health Physics, Fac. of Med., Univ.
of Fukui, 3Res. and Development, The Wakasa-wan Energy Res. Center, Tsuruga, Fukui, Japan1

Room A

Hisaya Shiozaki1, Yusuke Sasai1, Kazue Kitahiro1, Ryuta Suzuki1, Yutaka Jujo1, Ken Koshiba1,
Sachiko Hayashi2, Masanori Hatashita329

Treatment of advanced bladder cancer by regional hyperthermia combined with parthenolideand chemotherapy. A case report

Room AADMETECH Co.Ltd

29

17:30-18:30

29

Poster Viewing & Discussion

Room B

Room P

Room C
30
Room A
30
Room B
31
Room A
31
Room B－ 55 －

August 31 (Fri.)

Room A

Morning Lecture 9

9:10-9:40
Chairperson: Yoshihiko Maehara

Dept. of Surg. and Sci., Kyushu Univ.

ML09

An effective new thermal therapy treatment for pancreas cancer
Joan M.C. Bull, Robert A. Brown, Young Su, Theresa Dancsak
The Univ. of Texas Med. Sch. at Houston, Houston, TX

Break

9:40-9:50

Symposium 11

9:50-11:50

HIFU and non-invasive heating
Chairpersons: Charles Cain

Dept. of Biomed. Eng., the Univ.of Michigan

Shin-ichiro Umemura

Grad. Sch. of Biomed. Eng., Tohoku Univ.

S11-1

Transrectal high-intensity focused ultrasound (HIFU) for the treatment of localized prostatecancer: 13-year experience
Toyoaki Uchida, Tetsuro Tomonaga, Hakushi Kim, Sunao Shoji, Masanori Shima, Yohishiro
NagataDept. of Urology, Tokai Univ. Hachioji Hosp.

S11-2

The current development of HIFU ablation for hepatocellular carcinoma
Feng Wu
HIFU Unit, the Churchill Hosp., Oxford Univ. Hosp.

S11-3

MR guided focused ultrasound surgery(MRgFUS) for small breast cancer: The excisionlessclinical study
Hidemi Furusawa1, Junnichi Shidooka2, Masuko Inomata1, Emiko Hiravara1, Hiroshi Nakahara2,
Yukiko Yasuda1, Yorio Maeda1, Kansei Komaki1, Takashi Yamamoto1, Tomokazu Saito1
Dept. of Breast Surgical Oncol., Breastopia Namba Hosp., 2Dept. of Diagnostic Radiology,
Breastopia Namba Hosp.
1

S11-4

Progress in focused ultrasound heating technology
Kullervo Hynynen, Nicolas Ellens, Daniel Pajek
Dept. of Med. Biophysics, Univ. of Toronto－ 56 －

S11-5High intensity focused ultrasound: Irradiation set-up and its biological response

Grad. Sch. of Bio-Application & Systems Eng., Tokyo Univ. of Agric. & Tech., 2Grad. Sch. of
Biomedical Eng., Tohoku Univ., 3Grad. Sch. of Eng., Tohoku Univ., 4Clinical Res. Center for Child
Health and Developoment, 5Hitachi-Aloka Med., Ltd.

28

Takashi Mochizuki1, Shin-ichiro Umemura2, Shin Yoshizawa3, Toshio Chiba4, Taizo Kihara5, Kohji
Masuda11

Dept. of Biomed. Eng., The Univ. of Michigan

Room ACharles Cain

29

Histotripsy: Controlled mechanical sub-division of soft tissues by high intensity pulsed
ultrasoundRoom A

S11-6

29

Luncheon Seminar 3

12:00-13:00

Room C

Chairperson: Satoshi Kokura

Kyoto Pref. Med. Univ.

Treatment of bone metastases from breast cancer

30

LS3

Tetsuya Taguchi
Sponsored by DAIICHI SANKYO Co., LTD./ AstraZeneca K. K.

Room A

Dept. of Endocrine and Breast Surg., Kyoto Pref. Univ. of Med.

30

13:00-15:00

Medicine (Med, Clinical Results)
Kawasaki Saiwai Hosp.

Zeljko Vujaskovic
Dept. of Radiat. Oncol., Duke Univ. Med. Center

Room A

Current status of clinical hyperthermia in United States

31

Chairperson: Yoshiaki Tanaka

Room B

Summary 1

SU1-1

29

11:50-12:00

Room B

Break

31

Appraisal of hyperthermia as clinical modality in Indian subcontinent
Nagraj G. Huilgol
Div. of Radiat. Oncol., Nanavati Hosp., Mumbai

SU1-3
Jacoba van der Zee
Hyperthermia Unit, Dept. Radiat. Oncol., Erasmus MC - Daniel den Hoed Cancer Center
SU1-4

Current status of clinical hyperthermia in China
Shan-wen Zhang
Peking Univ. Cancer Hosp.
－ 57 －

Room B

SU1-2

SU1-5Current situation of clinical hyperthermia in Japan
Hiromi Terashima
Dept. of Radiat. Oncol., Harasanshin General Hosp.

Break

15:00-15:15

Award Ceremony of ICHO2012 and Closing Remarks

15:15-16:00

General Chairperson: Satoshi Kokura, Secretary General
Young Investigator Award Ceremony
Poster Presentation Award Ceremony: Physics & Engineering/ Biology Medicine
Chairperson: Koichi Ito

JSTM Scientific Committee

Informa/Yamamoto Editor’s Award Ceremony: Physics & Engineering/ Biology/ Medicine
Chairperson: Mark W Dewhirst

Editor of Int J Hyperthermia

Message from the next President of ICHOnot yet decided
Message from the next President of JCTM
Iwai Tohnai
Closing Remarks
Toshikazu Yoshikawa, President of ICHO2012
Takeo Ohnishi, Honorary President of ICHO&JCTM 2012, President of JSTM

－ 58 －

August 31 (Fri.)

Room B

9:10-9:40
Nagoya Prostatic Center, Hachiya Orthop. Hosp.

Role of hyperthermia in treatment of bladder cancer: Current status and future directions

Room A

Zeljko Vujaskovic

29

ML10

Room A

Chairperson: Kosuke Ueda

28

Morning Lecture 10

Dept. of Radiat. Oncol., Duke Univ. Med. Center

Hyperthermia enhancement and molecular mechanisms
Chairpersons: Tetsuo Akimoto

Room C

9:50-11:50

29

Symposium 12

Room B

9:40-9:50

29

Break

Dept. of Radiat. Oncol. and Particle Therapy, Nat’l
Cancer Center Hosp. East (NCCE)

DNA-PK activity is involved in the fast repair of DNA double strand breaks during thermal
radiosensitization

Enhancement of heat sensitivity by depression of DSB repair

Hyperthermia-induced homologous recombination deficiency provides novel anti-cancer
treatment opportunities
Berina Eppink1, Przemek M. Krawczyk2, Jeroen Essers1,3,4, Jan Stap2, Hanny Odijk1, Alex Zelensky1,
Thomas Soullie5, Joost Rens5, Timo L.M. ten Hagen5, Jacob Aten2, Roland Kanaar1,3
Dept. of Cell Biology & Genetics, Cancer Genomics Center, Erasmus Med. Center, 2Dept. of Cell
Biology & Histology, Univ. of Amsterdam, 3Dept. of Radiat. Oncol., Erasmus Med. Center, 4Dept.
of Vascular Surg., Erasmus Med. Center, 5Dept. of Surg. Oncol., Erasmus Med. Center1－ 59 －

Room B

S12-3

31

Dept. of Dentist. and Oral Surg. Heisei Memor. Hosp., 2Dept. of Oral Maxillofac. Surg. Nara Med.
Univ., 3Dept. of Otorhinolaryngol. Nara Med. Univ., 4Adv. Sci. Res. Lead. Develop. Unit, Gunma
Univ., 5Dept. of Radiat. Oncol. Nara Med. Univ.
1

Room A

Atsuhisa Kajihara1,2, Noritomo Okamoto3, Yousuke Nakagawa1,2, Akihisa Takahashi4, Takaaki
Kirita2, Takeo Ohnishi5

31

S12-2

Room B

Dept. of RI Med., Atomic Bomb Disease Inst., Nagasaki Univ., 2Dept. of Radiat. Oncol., Sch. ofMed., Nara Med. Univ.
1

30

Makoto Ihara1, Yutaka Okumura1, Takeo Ohnishi2

Room A

S12-1

30

Tetsuro Tamamoto

Dept. of Radiat. Oncol., Nara Med. Univ.

S12-4

Enhancement of hyperthermia-induced tumor cell death by 5-aminolevulinic acid
Taku Chibazakura1, Yui Toriyabe1, Kiwamu Takahashi2, Mariko Kawakami1, Shun-ichiro Ogura3,
Fuminori Abe2, Motowo Nakajima2, Tohru Tanaka2
Dept. of Bioscience, Tokyo Univ. of Agric., 2SBI Pharmaceuticals Co., Ltd., 3Frontier Res. Center,
Tokyo Inst. of Tech.

1

S12-5

Therapeutic effects of 5-aminolevulinic acid (ALA) on the growth of 3LL in combination withhyperthermia in mice
Kiwamu Takahashi1, Takeo Hasegawa2,3, Kazuko Uno2, Iuko Yasuda2, Atsuko Kishi2, Kaori
Sadamoto2, Fuminori Abe1, Takuya Ishii1, Motowo Nakajima1, Tohru Tanaka1
SBI Pharmaceuticals Co., Ltd, 2Dept. of Hyperthermia Med. Res. Lab. Louis Pasteur Center forMed. Res., 3Dept. of Molecular Gastroenterology and Hepatology, Kyoto Pref. Univ. of Med.

1

S12-6

Recombinant adenovirus-p53 (rAd-p53) transfer in combination with hyperthermia for advanced
cancer(a report of 44 cases)
Shanwen Zhang
Dept. of Radiotherapy, Peiking Univ. Cancer Hosp.

S12-7

Oncothermia – modulated electro-hyperthermia
Oliver Szasz
Oncotherm GmbH, Germany

Break

11:50-12:00

Summary 2

13:00-14:00

Basic (Physics)
Chairperson: Koichi Ito

Grad. Sch. of Eng., Chiba Univ.

SU2-1

Gerard C. van Rhoon
Erasmus MC Daniel den Hoed Cancer Center

SU2-2Paul R. Stauffer
Radiat. Oncol. Dept., Duke Univ.

SU2-3

Kagayaki Kuroda
Dept. of Human and Information Sci., Sch. of Information Sci. and Tech., Tokai Univ.

－ 60 －

Summary 3

14:00-15:00
28

Basic (Biology)
Dept. of Radiat. Oncol., Nara Med. Univ.

The enhancement of the hyperthermic effects using aureobasidiumu pullulans (ACFAgMax)

Development of oral cancer treatment using a new magnetic anticancer drug

Dept. of Oral and Maxillofacial Surg., Yokohama City Univ. Grad. Sch. of Med., 2Dept. of
Cardiovascular Res. Inst., Yokohama City Univ. Grad. Sch. of Med., 3Dept. of Oral and Maxillofacial
Surg., Tokyo Med. Univ., 4IHI Corp.

29

Itaru Sato1, Kenji Mitsudo1, Masaki Iida1, Hideyuki Nakashima1, Haruki Eguchi4, Toshiyuki
Koizumi3, Mitomu Kioi1, Yoshihiro Ishikawa2, Iwai Tohnai1

Room B

SU3-2

29

Dept. of hyperthermia Med. Res. Lab. Louis Pasteur Center for Med. Res., 2Dept. of Molecular
Gastroenterology and Hepatology, Kyoto Pref. Univ. of Med., 3Grad. Sch. of Materials Sci., Nara
Inst. of Sci. and Tech., 4Dept. of Radiological Tech., Suzuka Univ. of Med. Sci., 5Dept. of Res.
Center, Ikko Chem. Co.
1

Room A

Kaori Sadamoto1, Kazuko Uno1, Iuko Yasuda1, Atsuko Kishi1,3, Takashi Hasegawa3, Takenori
Yamashita4, Naomi Fujita5, Taku Harada5, Yasushi Harada5, Takeo Hasegawa1,2

29

SU3-1

Room A

Chairperson: Takeo Ohnishi

1Dept. of Radiotherapy, Peiking Univ. Cancer Hosp.

Yongheng Li

31

Dept. of Radiotherapy, Peiking Univ. Cancer Hosp.

Room B

Peritoneal perfusion of rAd-p53 combined with thermo-chemotherapy for peritoneal
carcinomatosis model of advanced cancer (a report of forty-one cases )

30

SU3-4

Room A

Shaowen Xiao

30

Clinical effectiveness of recombinant adenovirus-p53 combined with hyperthermia in advanced
soft tissue sarcoma (a report of 30 cases)

Room C

SU3-3

Room A
31
Room B－ 61 －