to Mino-o

Bampaku-kinen-koen
Ibaraki

YamadaShin-Osaka

JR Kyoto Line

Minami-ibaraki

Ibaraki-shi

Hankyu Kyoto Line

zuk
aL
ine

to Kyoto

Hankyu Kobe Line

Awaji
Juso

Hanshin Main Line
JR Kobe Line

to KobeTenjimbashisuji 6-chome
Osaka(Umeda)Kadomashi

Yodoyabashi

Keihan Main Line

SubwaySakaisuji Line

SubwayMidosuji Lineto Kyoto

Kintetsu Railway

Namba

to NaraShin-Imamiya(Dobutsuen-mae)
Tennoji

JR Shinkansen
JR
Subway Sakaisuji Line / Kita-Osaka Kyuko Railway
Subway Sakaisuji Line
Hankyu Line
Keihan Line
Osaka Monorail
Other private railway
Bus Route

Nan
kai M
ain L
ine

Tengachaya

KansaiInternational Airport
JR Hanwa Line

to Wakayama■ Suita District■ Toyonaka District
Ishibashi Sta.
Inter-Campus Shuttle Bus
Bus Stop
Ishibashi Gate
Pond
Ishibashi-Handai-shita

Institute forProtein Research

Main Library
School of Letters,
Graduate Schoolof Letters

Institute of Scientific andIndustrial Research

OnoharaSchool of Engineering Science,
Graduate Schoolof Engineering Science

Engineering Science
International Hall

Shibahara Sta.

Osaka Prefectural Route 2

Research Center for Ultra-High Voltage
Electron Microscopy

Icho Kaikan
Pond
Handai-byoinSchool of Engineering,Research Institute for Graduate School of
East Gate mae Sta.
Microbial Diseases
Faculty of Medicine,
Engineering
Graduate School of
Medicine
Osaka University
Senri Gate
Hospital
Handai-Honbu-mae
Bus Stop
University Co-op
West Gate
Osaka University
Dental Hospital

Administration
Bureau

e
Lin
nri
Se
yu
nk
Ha

Main Gate
Osaka Monorail

Shimizu
Inter-Campus
Shuttle Bus
Bus Stop

Immunology Frontier
Research Center

Kita-Senri Sta.

1966 The Manufacturing Center inaugurated as an on-campus joint education and research facility

Toyokawa Sta.

Osaka MonorailInterdisciplinary
Research Building

Center for Scientific Instrument
Renovation and
Manufacturing SupportndPo

Center for Scientific Instrument
Renovation and
Manufacturing Support

Engineering Science
J-WingSchool of Science,
Graduate School of Science

2007 Progressively reorganized the Manufacturing Center and established the Renovation Center ofInstruments for Science Education and Technology

Handai-byoin-mae

HankyuSenri Line

JR Shinkansen

to KobeSaito-nishi

Senri-Chuo

Shibahara

Hotarugaikeara

History

Osaka
International Airport(Itami)Hankyu Takarazuka LineDue to the recent austere financial situation, it has been increasingly difficult for national universities maintain and improve their research infrastructure. Coping with the difficult circumstances, universities are strongly
requested to self-manage maintaining their research infrastructures and make a roadmap for improving themwith mid- and long-term outlooks. Osaka University Master Plan for the Maintenance and Improvement ofResearch Infrastructure had been laid down as a basic guideline in mid- and long-term spans and the CRM has
been working along with the university headquarter to accomplish the goal of the master plan.
The Research Facilities Renovation Support Division thus has been further promoting thecampus-wide reuse and shared-use of research equipments and instruments in addition to the assembling their campus-wide information to promote their shared-use and further enhance the effective useof the university’ s research assets. It is now an important task for the Osaka University to establish acomprehensive campus-wide shared-use system for research equipments and instruments, and we shallcontribute for its establishment.
Through our craftsmanship at the machine and glass shops in Manufacturing Support Division, we
have continued supporting educational and research activities in Osaka University for more than a half
century since the inauguration of the Manufacturing Center in 1966, the forerunner of the division. Even
nowadays the request from campus-wide researchers for our craftsmanship remains high. The services
providing by the division are machining and glassworks for the prototyping, modification, and repair ofexperimental devices and instruments. In addition, Student Shop, a shop to do-it-yourself for students,
staffs, and researchers, is also available and we have been continuously adding enhancements to the shop foreasier and better user environment through adding high-performance machine tools and making expensive
tools available for loan. The Manufacturing Support Division pledges continuous enhancement of ourservices and supports to meet customers’ need.
Although we are a small facility, it is our sincere desire to better serve students and researchers at theentire Osaka University to assist their educational and research activities through providing more effective
and advanced aids and services by hearing our customers’ voices. We wish your continued support and kindencouragement for us.

IshibashikTa(1) Administrate campus-wide information on research equipments and instruments andpromote their shared-use(2) Promote “reuse” of research equipments and instruments for their effective use(3) Support research and educational activities through providing machining and glasswork services.

to Takarazuka

Suita
CampusKita-Senriyunk

Director

ToyonakaCampusHa

Toshiaki Munakata

The Center for Scientific Instrument Renovation and Manufacturing Support (CRM) had beenrelaunched in April 2014 through the reorganization of its preceding body, Renovation Center of Instruments for Science Education and Technology. After the pioneer work for establishing the new organization by Professor Toshihiro Tanaka, the first Director of the new Center in 2014 and 2015, including therelocation of the Manufacturing Support Division to new Interdisciplinary Research Building, as of April
2016, I was honored to succeed Professor Tanaka and now serve as the Director of the Center. Professor
Hidetoshi Kobayashi of the Graduate School of Engineering Science became Deputy Director.
The CRM consists of two divisions, Research Facilities Renovation Support Division and Manufacturing Support Division, and has been providing supports for research and educational activities in Osaka
University as a campus-wide support facility under the three principle objectives and missions below:

Ac c e s s

A Message from the Director

Main Gate

Koen-higashiguchi Sta.
Expo '70 CommemorativePark

Yamada Sta.

Osaka Prefectural Route 2

Bampaku-kinen-koen Sta.

2014 Reorganized into the Center for Scientific Instrument Renovation and Manufacturing Support

Organizational Chart

Director

Research Facilities
Renovation
Support Division

Joint-use Promotion
Support Section
Scientific Instrument
Technical
Support Section

Deputy Director

Chemical Analysis Section
Manufacturing Support
Division

Machine Shop
Glass Shop
Mechanical Engineering
Student Shop

1-2, Machikaneyama-cho, Toyonaka-shi, Osaka 560-0043 Japan
Tel: 06-6850-6709, Fax: 06-6850-6052

8-1 Mihogaoka, Ibaraki-shi, Osaka 567-0047 Japan
Tel: 06-6879-4781, Fax: 06-6879-4781

Transport AccessTransport Access

By Rail:● About 1.5km (25-min. walk) from Ishibashi Station on the Hankyu Takarazuka Line
● About 500m (8-min. walk) from Shibahara Station on the Osaka Monorail● About 1.7km (30-min. walk) from Kita-Senri Station (final stop) on the Hankyu Senri Line
● About 1.2km (20-min. walk) from Handai-byoin-mae Station on the Osaka Monorail

By Rail:By Bus:● Hankyu Bus

Board the bus bound for Handai-Honbu-mae or Ibaraki Mihogaoka at Senri-Chuo
Board the Handai-byoin Route at Kita-Senri● Kintetsu Bus
Board the bus bound for Handai-Honbu-mae (via JR Ibaraki Station)
at Hankyu Ibaraki-shi Station
For all bus routes it is about 1km (15-min. walk) from Handai-Honbu-mae bus stop

Center for Scientific Instrument Renovationand Manufacturing Support, Osaka University

http://www.reno.osaka-u.ac.jp
info@reno.osaka-u.ac.jp

Center for Scientific Instrument Renovationand Manufacturing Support
Osaka University

1. Efforts to effectively use university assets

4. Efforts to support research activities of

Based on the “Master Plan for Maintenance and Improvement of
Osaka University Facilities,” the division provides support for
improving and enhancing education and research environments,
including facility maintenance, by renovation, restoration, repair
and upgrading of facilities and instruments used for education andresearch throughout the campus. This support makes the repaired
and upgraded instruments available to the entire university throughshared use of resources as reuse facilities and instruments.

We are working to develop the use environment by preparing
English versions of brochures with information about reuse
instruments and the English website, and establishing support
organization as the point of contact for support services by staff
with English language skills. Through the provision of these
support services, we are supporting the research activities ofinternational students and foreign researchers at the university.

Support for shared use of research facilities, instruments, etc.
Center for Scientific Instrument Renovation and Manufacturing Support

international students and foreign researchers

Requests forsupport toachieve shareduse of researchfacilities,
instruments, etc.

Interviews,
reviews,
screenings,
selection

Support for the Being available
expenses
for shared use asneeded forreuse facilities
repairs andandupgrades, etc. instruments ona university-widebasis

Department that owns the shared use instrument

2. Efforts to provide users of reuse facilities
and instruments with technical support
for acquiring and improving
their knowledge and technical skills

We regularly hold various short courses, seminars, and other events
to help users of reuse facilities and instruments learn and improvespecialized and practical knowledge and techniques relating to
instrumental (instrument-based) analysis. These short courses andseminars go beyond just providing technical information on theutilization of reuse facilities and instruments and promote exchange
of information and views with the instructor and among participants,
and serve as a forum for valuable interaction between students,
researchers and technicians invarious fields. Technical staff arealso deployed to provide training
for the use of the instrument,
technical guidance, advice,consultation and other assistance to meet the needs ofusers.

3. Efforts to promote shared use
Users’ Convenience has been improved by adopting our own
online reservation system. To improve convenience even further, afeature has been added for reviewing, changing and cancelingreservations from a person's own page on the system, and an
inquiry feature has been introduced as a new communication tool.
This feedback function enables close bidirectional communication
with users.
Also, to promote the use of reuse facilities and instruments,
the relevant information is disseminated and furnished using public
relations tools such as brochures and a website.

Procedure for on-campus shared use of reuse instruments
Reuse instrument user

Application
for useUse of instrument(measurement/analysis etc.)

Confirmationof use4

1

Request for
Receipt of application permission to use
for use(adjustments
in scheduling, etc.)
Center for Scientific Instrument Renovation 2
and Manufacturing Support

6
7

X-ray diffractometer(XRD)

Elemental analysis instrument(ICP, EPMA, WDX, etc.)

Through the online "Recycle Bulletin Board" on the center's
website, we are aiming at effective utilization of research andeducation facilities, instruments or other equipment that are nolonger needed. In order to reduce the environmental impact andoverall cost by reusing existing assets owned by the university andpromote its effective utilization even further, we are aiming at
effective utilization of its assets by setting up a recycle bulletinboard for people outside the university, and providing information
through our website on a broadly disseminated basis.

6. Efforts to contribute to

local communities and society

Some reuse facilities and instruments are available for use bypeople outside the university and through contract-based analysis
we support research and development at universities, research
institutions, companies, and other organizations, and promote theuse of reuse facilities and instruments. Furthermore, we not only
perform contract-based analysis, we also strive to contribute to
local communities and revitalize society in our area throughutilization of reuse facilities and instruments in areas by providing
consultation on analytical techniques and technical assistance
while observing what is going on by being present.

7. Efforts to build cooperative relationships
between universities supportedby the Facility Support Center
Development Program

The initiative is to promote cooperative relationships between
universities participating in the Facility Support Center Development Program and we are working collaboratively between
the universities to solve issues related to the promotion ofshared use of facilities and instruments by effectively utilizing
the each university's strengths such as technologies andknow-how and networks in the region.

8. Efforts to support research activities

by providing chemical analysis services(Toyonaka Campus)

As one of the research support activities offered by the
Research Facilities Renovation Support Division, qualitativeand quantitative analysis of the elements contained in a sample(primarily consist of metallic elements) shall be carried out at
the request of the users.

NMR spectrometers with a variety ofcapabilities, ranging from 200 MHz
to 700 MHz, either for liquids orsolids (or both), are available. The
multinuclear and two-dimensional
NMR capabilities are available, andalso with the photo-irradiation
system changes in reaction kinetics
can be measured.

Various ionization techniques areavailable such as MALDI, ESI, APCI,FAB, and DART. FTICR-MS are alsoavailable for high-to-ultrahigh mass
resolution and very high massaccuracy measurements. Furthermore, different MS/MS analyses arefeasible using CID, ETD, and ECD,
depending on the purpose of theanalysis.

Various X-ray diffraction methods areavailable to enable measurement capability across a wide range of samples, suchas single crystals, powders, thin films,
and ultramicrocrystals and applied tocharacterization of crystal state andstructure, and determination of particle
size distribution. The optics attachment isavailable to micro-area X-ray diffraction
measurement of small areas of less than
one square millimeters.

By using various analytical instruments, qualitative and quantitative
analysis, ranging from screening
analysis to precision analysis, is also
permitted. When ICP is employed,
high-precision trace-element analysis can be carried out with highsensitivity at the ppb level.

Electron spin resonance(ESR) spectrometer

Spectrometer(IR, Raman, UV/Vis/NIR)

Surface analysis instrument(XPS, SIMS, etc.)

Electron microscope(TEM, SEM (FE-SEM))This instrument is used for highly
sensitive detection of radicals andtransition metals, identification ofradical molecular species, andstructural and quantitative analysis.
Some ESR instruments allows themeasurement of temperature
variation at ultra-low temperatures.

Variable-temperature studies can be
carried out with FT-IR spectrometerequipped with a cryostat or heatedcell. The FT-IR measurement is also
performed using the ATR method
and high-sensitivity reflection
method (RAS method). FT-IR microscopic analysis of a microscopic area
can also be performed using an
FT-IR equipped with an infrared
microscope.

XPS provides information about elemental
composition and chemical bonding statein the range of several nms from theoutermost surface. It can also be used to
examine the element distribution in thedepth direction. SIMS has the capability ofidentification and determination of trace
impurity elements at the ppb level. The
technique also provides elemental depth
profiles over a wide range of depths fromseveral nm to several tens of µm.

FE-SEM can be used not only for theobservation of specimens, but also forthe elemental analysis of the sample incombination with EDS. In addition tomorphological observation, TEM can beused to observe electron diffraction
patterns that are indicative of theircrystal structures. The various types ofsample preparation instruments areavailable for the preparation of samples
for examination in the TEM and SEM.

Other instruments
Spectrometer

Morphological observation instrument

Biotechnology-related instrument

Circular dichroism (CD) spectrometer
Stopped-flow system
Fluorescence spectrophotometer

Scanning probe microscope (SPM)
Atomic force microscope (AFM)

DNA sequencer
Micro-array analysis system
Surface plasmon resonance (SPR) spectrometer
Flow cytometer

Thermal analysis instrument
Isothermal titration microcalorimeter (ITC)
Differential scanning calorimeter (DSC), etc.

Imaging instrument
Magnetic resonance imaging (MRI) instrument
Fluorescence imaging system
Deconvolution microscope

Instrument used for protein experiments
Chromatography system
Analytical ultracentrifuge

In addition to the above instruments, our broad portfolio includes laser devices, machine tools and other instruments.

86Permission/
Approval to use

Mass spectrometer(MS)

Nuclear magnetic resonance(NMR) spectrometer

If you would like to use reuse instruments, please fill in the application form through the following website. Furthermore, if you
have any questions about analytical techniques and instruments or if there are points that you would like to clarify or discuss,please feel free to contact us via contact form on our portfolio page.
https://www.reno.osaka-u.ac.jp/reuse-cam/Receipt of report/
Payment

Finalization ofRequest for
usage information/
confirmation of use 5 Calculationof usage fees3

As of October 2016, 104 instruments are available for shared use by teaching staff, researchers and students as reuse facilities and instruments on auniversity-wide basis to support research and education activities. The center acts as the point of contact for their users and deal with user requirements
regarding shared use of facilities and instruments. The following provides a summary of reuse facilities and instruments.

5. Efforts to promote the utilization of
the University's assets

Identifying
facilities andinstrumentsthat can berenovated forshared use

Regarding on-campus shared use of reuse instruments available to the entire university

Confirmationof useDepartment that owns reuse instrument* The Research Facilities Renovation Support Division of this center acts as the point ofcontact, provides support needed by those who require instruments, and supports thepromotion of on-campus research activities.

Regarding shared use of reuse instruments also available to off campus users
Some reuse instruments (19 instruments as of October 2016) and analytical testing services, which are performed with their instruments and conducted byskilled staff, are available upon request to off campus users to perform local and social contribution activities through collaboration with the industry andworking with the community. If you would like to use reuse instruments (those available to off-campus users), please fill in the application form through thefollowing website.

https://www.reno.osaka-u.ac.jp/reuse-offcam/

Manufacturing Support Division

Research Facilities Renovation Support Division

In the Research Facilities Renovation Support Division, we are making the following efforts to facilitate shared use of on-campus facilities
and instruments and provide the technical support necessary for carrying out research, and to provide administrative support, such as theuse of instruments and facilities.

Located in the Toyonaka Campus, the Manufacturing Support Division, actively carried on the projects of the former Manufacturing
Center, has been providing services for prototyping and remodeling of research and experimental equipments and instruments
and/or their parts through machining and glass works on-request from campus-wide reserachers, as well as student classes and technical training courses for machining and glassworks. In addition, the division also operates a Mechanical Engineering Student Shop
where students, staffs, and reserachers can work on their own fabrication projects using various machining tools with supports fromtechnical staff.

Machining and Glasswork Services■ Machining Service
The Main Machine Shop offers custom machining and fabrication
services of metal and resin components and equipments asrequested in addition to a welding and minor repair services.The
shop owns various types of NC and CNC machining equipments tomeet diverse request from researchers on machining/fabricationand modification of their experimental apparatus and components.
Vacuum leak testing service is also available through the OpenWorkshop.

■ Glasswork Service
The Main Glass Shop offers services such as custom glass
product manufacturing and repairs and mechanical processingof glass/ceramic materials.The shop can craft not only dewar
flasks , which is essential components in low-temperature experiments , but also a wide range of glassworks covering from generalglass products to mechanical processing and fabrication with fineceramic materials.

Supporting
On-Campus Do-It-Yourself Fabrication■ Open Workshop (Student Shop)
The Student Shop is an open workshop where students, staffs,
and researchers can work on their own fabrication projects
using various machining tools. Technical staff members arealways present to provide guidance and advice on how to
operate machine tools and how to fabricate parts designed byusers. Machining equipments such as lathes, vertical millingmachines, horizontal milling machines, contour machines, band
saws, and drilling machines are available and most types offabrication processes can be completed in the shop. Users
must undergo a safety training session prior to using
equipments in the shop.
When users come upon special fabrication processes
which are difficult for the users to complete (e.g., welding anddischarge machining), users can ask technical staffs in the shop
for on-the-spot assistance. In addition, an array of large-sizeand specialized tools is also available.

Technical Training Courses
Technical training courses are held during every summer andspring break in order to improve fabrication techniques for students(B4 / graduate students), staffs, and researchers. Machining andglasswork courses are available. The courses are designed so thatparticipants can acquire general fabrication and machining skills
necessary to make custom items for their research.

Content of the Courses (4 days long each)

Machining
CourseMachining with lathes and milling machines:
Threading, cap nut machining,round bar step milling, block milling,
grooving, pocket machining, etc.

Glasswork
CourseConnection of glass pipes withdifferent diameters, making T-pipes,
U-pipes, traps, etc.

Safety Training Sessions
The sessions are required to use the Student Shop and areoffered at the beginning of summer break every year. Pleasecontact us in case you would like to use the Student Shop andneed to have the sesseion rather than having scheduled
sessions.

Stock Room
Materials and supplies necessary for experiments, such as metaland glass materials, electronic parts, vacuum and piping / tubing
components are available on charge basis. Please visit our
website for more information.