長崎大学医学部業績集

放射線生命科学部門
A

欧2．研究業績

幹細胞生物学研究分野（原研幹細胞）

文A-a
1. Milliaras K, Li TS, Luthringer D, Terrovitis J, Cheng K, Chakravarty T, Galang G, Zhang Y, Schoenhoff F, Van Eyk J,Marb n L, Marb n E：Safety and efficacy of allogeneic cell therapy in infarcted rats transplanted with mismatchedcardiosphere-derived cells. Circulation 125(1): 100-112, 2012 (IF:14.739) ＊☆
2. Ueda K, Tanaka T, Hayashi M, Tanaka N, Li TS, Hamano K：What proportion of lung cancers can be operated bysegmentectomy? A computed-tomography-based simulation. Eur J Cardiothorac Surg 41(2): 341-345, 2012 (IF:2.550) ＊3. Ueda K, Tanaka T, Hayashi M, Tanaka N, Li TS, Hamano K：Clinical ramifications of bronchial kink after upperlobectomy. Ann Thorac Surg 93(1): 259-265, 2012 (IF:3.741) ＊4. Yoshida T, Goto S, Kawakatsu M, Urata Y, Li TS：Mitochondrial dysfunction, a probable cause of persistent oxidative
stress after exposure to ionizing radiation. Free Radic Res 46(2): 147-153,2012 (IF:2.878) ＊○▽5. Kubo M, Li TS, Kurazumi H, Takemoto Y, Ohshima Y, Murata T,Katura S, Morikage N, Furutani A, Hamano K：
Hypoxic preconditioning enhances angiogenic potential of bone marrow cells with aging-related functional impairment.
Circ J 76(4):986-994, 2012 (IF:3.766) ＊☆
6. Li TS, Cheng K, Malliaras K, Smith RR, Zhang Y, Sun B, Matsushita N, Blusztajn A, Terrovitis J, Kusuoka H, Marb n L,
Marb n E：Direct comparison of different stem cell types and subpopulations reveals superior paracrine potency andmyocardial repair efficacy with cardiosphere-derived cells. J Am Coll Cardiol 59(10):942-953, 2012 (IF:14.156) ＊☆
7. Cheng K, Malliaras K, Li TS, Sun B, Houde C, Galang G, Smith J, Matsushita N, Marb n E：Magnetic enhancement ofcell retention, engraftment and functional benefit after intracoronary delivery of cardiac-derived stem cells in a rat modelof ischemia/reperfusion. Cell Transplant 21(6): 1121-1135, 2012 ＊☆
8. Ueda K, Tanaka T, Hayashi M, Li TS, Hamano K：Verification of early removal of the chest tube after absorbable meshbased pneumostasis subsequent to video-assisted major lung resection for cancer. World J Surg 36(7): 1603-1607, 2012
(IF:2.362) ＊9. Cheng K, Blusztajn A, Shen D, Li TS, Sun B, Galang G, Zarembinski TI, Prestwich GD, Marb n E, Smith RR, Marban
L：Functional performance of human cardiosphere-derived cells delivered in an in situ polymerizable hyaluronan-gelatinhydrogel. Biomaterials 33(21): 5317-5324, 2012 (IF:7.404) ＊☆
10. Kubo M, Li TS, Kurazumi H, Takemoto Y, Ohshima M,Yamamoto Y, Nishimoto A, Mikamo A, Fujimoto M, Nakai
A,Hamano K：Heat shock factor 1 contributes to ischemia-induced angiogenesis by regulating the mobilization andrecruitment of bone marrow stem/progenitor cells. PloS One 7(5): e37934, 2012 (IF:4.092) ＊☆
11. Nakamoto M, Hirose M, Kawakatsu M, Nakayama T, Urata Y,Kamata K, Kaminogo M, Li TS, Nagata I：Serum Sglutathionylated proteins as a potential biomarker of carotid artery stenosis. Clin Biochem 45(16-17): 1331-1335, 2012(IF:2.076) ＊○12. Inadomi C, Murata H, Ihara Y, Goto S, Urata Y, Yodoi J, Kondo T, Sumikawa K：Overexpression of glutaredoxin
protects cardiomyocytes against nitric oxide-induced apoptosis with suppressing the S-nitrosylation of proteins andnuclear translocation of GAPDH. Biochem Biophys Res Commun 425(3): 656-661, 2012 (IF:2.484) ＊ ○13. Takemoto Y, Li TS, Kudo M, Ohshima M, Kurazumi H, Ueda K, Enoki T, Murata T, Hamano K：The Mobilization andRecruitment of C-Kit+ Cells Contribute to Wound Healing after Surgery. PLoS One. 7(11):e48052, 2012 (IF:4.092)＊☆
14. Barth AS, Zhang Y, Li TS, Smith RR, Chimenti I, Terrovitis I, Davis DR, Kizana E, Ho AS, O'Rourke B, Wolff AC,Gerstenblith G, Marban E. Functional impairment of human resident cardiac stem cells by the cardiotoxic antineoplastic
agent trastuzumab. Stem Cells Transl Med 1(4): 289-297, 2012 ＊☆
15. Ono Y, Masuda S, Nam HS, Benezra R, Miyagoe-Suzuki Y, Takeda S. Slow-dividing satellite cells retain long-term selfrenewal ability in adult muscle. J Cell Sci 125(Pt 5): 1309-1317, 2012 (IF:6.111) ＊☆
16. Hisatomi K, Mukae H, Sakamoto N, Ishimatsu Y, Kakugawa T, Hara S, Fujita H, Nakamichi S, Oku H, Urata Y, Kubota
H,Nagata K, Kohno S. Pirfenidone inhibits TGF-β1-induced over-expression of collagen type I and heat shock protein 47
in A549 cells. BMC Pulm Med 12: 24, 2012 ＊A-b
1. Kurazumi H, Li TS, Kubo M, Ikenaga S, Mikamo A, Hamano K：Mechanical stress supresses the proliferation andimproves the differentiation of cardiac stem cells and increases the release of paracrine factors.ASCVTS 20th ANNUAL
MEETING Program.p283.
2. Takemoto Y, Li TS, Ohshima M, Kurazumi H, Kubo M, Ueda K, Enoki T, Hamano K：The mobilization and recruitmentof bone marrow-derived stem cells contribute the acceleration of wound healing after surgery.European Society for143

Surgical Research(ESSR)2012. 47th Annual Congress Program.p37.

B邦文

B-b
1. 小野悠介: 骨格筋部位特異的なサテライト細胞の性質と加齢による変容, 基礎老化研究．36 (3) 51-53, 2012
2. 李 桃生：心筋再生における細胞ソースの選択、細胞品質およびデリバリ方法の改善方策.再生医療増刊号
11:217, 2012
3. 藏澄宏之、久保正幸、森景則保、美甘章仁、李 桃生、濱野公一：血管再生療法の治療効果を増強する低酸素
プレコンディショニングは加齢動物の骨髄細胞に対しても有効か？.日本外科学会雑誌113（臨時増刊号2）p391.
4. 竹本圭宏、李 桃生、久保正幸、原田栄二郎、上杉尚正、榎 忠彦、濱野公一：手術侵襲による骨髄由来幹細胞の動員および集積が術後創傷治癒に関与する. 日本外科学会雑誌113（臨時増刊号2）p422.
5. 藏澄宏之、李 桃生、山本由美、西本 新、久保正幸、濱野公一：メカニカルストレスが細胞移植による心筋再生療法に対して及ぼす影響. 再生医療増刊号11:283, 2012

B-c
1. 李 桃生、川勝美穂、小野悠介、後藤信治、浦田芳重：急性放射線に対する抗酸化剤ニカラベン投与の効果.
第8回広島大学-長崎大学連携研究事業カンファランス報告書.ｐ.7, 2012
2. 小野悠介，川勝美穂，後藤信治，浦田芳重，李 桃生: 骨格筋部位特異的なサテライト細胞の性質と加齢による変化. 第35回日本基礎老化学会大会抄録集
3. 小野悠介: 骨格筋幹細胞の不均一性. 第35回日本分子生物学会年会抄録集
4. 小野悠介，川勝美穂，後藤信治，浦田芳重，李 桃生: サテライト細胞集団における幹細胞様細胞の同定. 第67回日本体力医学会大会抄録集

B-d1. 李 桃生：iPS細胞医療関連. 朋百126: ｐ8-9, 2012

論文数一覧
2012

A−a−

A−b−

A−c−

A−d−

合計

SCI

B−a−

B−b−

B−c−

B−d−

合計

総計

16200181605411028

合計

総計

1317

学会発表数一覧
A−a−
2012

A−b−
シンポジウム

学会

031

合計

B−a−

41

B−b−
シンポジウム学会

48

論文総数に係る教員生産係数一覧

2012

欧文論文総数

教員生産係数SCI 掲載論文数

教員生産係数論文総数（欧文論文）

欧文論文総数（SCI 掲載論文）

0.643

4.5

0.889

4

Impact factor値一覧
2012

Impact factor

教員当たり Impact factor

論文当たり Impact factor

70.451

17.6134.403144