PIXUL™ Multi-Sample Sonicator
Catalog No. 53130(version A6)

Copyright 2022 Active Motif, Inc.

PIXUL™ Multi-Sample Sonicator
powered by Matchstick Technologies
PIXUL™ is sold under an exclusive license to patents owned by Matchstick Technologies Inc. andUniversity of Washington, specifically Matula, T.J.; Bomsztyk, K.; Darlington, G.P., Maxwell, A.D.;
MacConaghy, B.E., Reed, J.
“Ultrasound system for shearing cellular material”. US Patent US10809166. European Patent
EP3169451.
Catalog No. 53130
activemotif.com

TABLE OF CONTENTS

Page

Active Motif Limited Warranty. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .1
General Warnings. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2
Overview . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3
Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4
Technical Specifications. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5
Included Accessories . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5
PIXUL™ Multi-Sample Sonicator Exterior Components . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6
Installing the PIXUL Multi-Sample Sonicator. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7
Operating the PIXUL Multi-Sample Sonicator . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11
Maintenance . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13
Touchscreen Messages and Errors. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15
References. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16
Appendix
Section A. PIXUL Sonication Parameters Guide . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .17
Section B. Troubleshooting Guide. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 8
Section C. WEEE Statement . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 19
Section D. FCC & IC Statement . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20
Section E. Icon Legend . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 21
Technical Services . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 22

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Active Motif Limited Warranty
Active Motif warrants that the PIXUL Multi-Sample Sonicator will be free from defects for 12 months
from the date of delivery when used under normal working conditions and in accordance with manuals
and other documents. Any component that proves defective during this period will be repaired or
replaced at no cost to the purchaser. Active Motif will provide a shipping container and instructions
for the customer to return the instrument for repair or replacement. All shipping charges during thewarranty period will be paid by Active Motif. In the event of a warrantable defect, please contact Active
Motif for a return authorization and instructions prior to returning any instrument or parts.
The warranty is void if failure of the instrument or parts, including all firmware or hardware, hasresulted from accidents, abuse, improper maintenance, usage, or repair, or misapplication by
the customer. It is also void if damage is cause by any unauthorized modifications made to the
instrument.
The warranty is limited to repair or replacement only, is not transferable, and is available only to theoriginal purchaser.
The warranty is void if the instrument is run without Active Motif Coupling Fluid (cat. no. 53136) inthe cooling reservoir. Coupling Fluid not only acts as the cooling liquid, but is also required for thetransmission of energy from the transducers to solution in the wells. Failure to run the instrument
without Active Motif Coupling Fluid will damage the transducers.
The warranty is void if the instrument is run without the proper plate (cat. no. 53139) or without liquid/water in every well of the columns in the 96-well plate that are being sonicated. Permanent damage tothe transducer and electronic circuits could result if the transducer is operated without liquid/water inevery well of the columns in the 96-well plate that are being sonicated.
Except as otherwise stated above, Active Motif’s standard Terms and Conditions apply. See www.
activemotif.com/terms-conditions for more information.
Information in this manual is subject to change without notice and does not constitute a commitment
on the part of Active Motif, Inc. It is supplied on an “as is” basis without any warranty of any kind, either
explicit or implied. Information may be changed or updated in this manual at any time.
This documentation may not be copied, transferred, reproduced, disclosed, or duplicated, in whole
or in part, without the prior written consent of Active Motif, Inc. This documentation is proprietary
information and protected by the copyright laws of the United States and international treaties.
The manufacturer of this documentation is Active Motif, Inc.
© 2022 Active Motif, Inc., 1914 Palomar Oaks Way, Suite 150; Carlsbad, CA 92008. All rights reserved.
All trademarks, trade names, service marks or logos referenced herein belong to their respective
companies.

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1

General Warnings
Don’t run the PIXUL™ Multi-Sample Sonicator without PIXUL Coupling Fluid (Cat. No. 53136).
If low pressure error message appears on PIXUL screen, please stop the run, power off, remove
plate, close lid, and contact Active Motif. DO NOT continue to run PIXUL bypassing the message
under any circumstances.
Tilting the PIXUL instrument can result in spillage of Coupling Fluid.
Do not unplug or power off the PIXUL instrument during a run. Loss of power to the instrument
while a file is open can result in corruption of the data file and operating system.
Coupling Fluid must be carefully monitored. If changes in Coupling Fluid transparency, color, or
texture are observed, power off the instrument, drain Coupling Fluid completely, and replenish
with fresh Coupling Fluid. It is recommended to change PIXUL Coupling Fluid every 2 months.
Running the PIXUL unit with no/low Coupling Fluid OR low pressure error will damage the PIXUL
device.
PIXUL Coupling Fluid temperature should be approximately 15°C at the start of the sonication
run. Don’t exceed a Coupling Fluid temperature of 35°C during sonication. If Coupling Fluid
temperature is maintained within this range, in-well thermal monitoring indicates that thetemperature of the sample is within the normal range experienced by samples in all major
sonication instruments (please see referenced publication #1 on page 16).
Only use room temperature (not previously frozen) 96-Well PIXUL Plates (Cat. No. 53139) with the
PIXUL instrument. Place plates with well A1 in the upper left corner. All wells in columns being
sonicated MUST be filled with fluid. Do not reuse plates from partial runs, as this can lead toissues with shearing consistency and sample contamination.
Don’t lift the external lid during processing of samples. Lifting the external lid will stop the run,initiating drainage of PIXUL Coupling Fluid from under the plate, necessitating re-circulation of
Coupling Fluid to start over from the beginning processing samples. The run will not resume fromthe point in time it was interrupted.
Any technical modifications to the device are prohibited. Service works may be carried out only
by qualified personnel or under the supervision of qualified personnel.

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Overview
Active Motif’s PIXUL™ Multi-Sample Sonicator is a high-throughput instrument for mechanicalshearing of DNA, RNA, chromatin, or protein from purified samples, cells, or tissue. This systemutilizes ultrasound transducers to create focused ultrasonic waveforms, transmitted through
PIXUL Coupling Fluid, to a 96-well microplate (cat. no. 53139). This flexible system allows for up
to 12 unique sonication parameters (one for each column of wells) to be set in the 96-well plate,generating consistent and reproducible fragmentation profiles in just 10-30 minutes per plate,depending on sample type.

product
PIXUL™ Multi-Sample Sonicator

formatcatalog no.

1-96 samples

53130*The PIXUL™ Multi-Sample Sonicator is powered by Matchstick Technologies.
PIXUL™ is sold under an exclusive license to patents owned by Matchstick Technologies Inc.
and University of Washington, specifically Matula, T.J.; Bomsztyk, K.; Darlington, G.P. Maxwell,
A.D., MacConaghy, B.E.., Reed, J. “Ultrasound system for shearing cellular material”. US Patent
US10809166. European Patent EP3169451.

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3Introduction
PIXUL™ Multi-Sample Sonicator
Next-generation sequencing applications, such as ChIP-Seq, RNA-Seq, RIP-Seq, exome, andwhole genome sequencing, require precise sample fragmentation (200-600 bp) for compatibility
with short read sequencing platforms. Shearing by mechanical sonication, as opposed toenzymatic methods, is preferred for its unbiased nature and ability to produce a relatively narrowfragmentation profile. However, the currently available sonication systems can be incompatible
with high-throughput sample processing. The PIXUL Multi-Sample Sonicator provides a flexible
and reproducible shearing profile for up to 96 samples processed in parallel.
Furthermore, high-throughput sonication on other platforms is currently limited by the cost of
consumables (tubes, plates, and reagents). However, the low cost, round-bottom plates (Cat. No.
53139) used in the PIXUL instrument are compatible with cell culture and shearing, eliminating
sample transfer steps that are inconvenient and can lead to loss of sample. Furthermore, the
PIXUL Coupling Fluid does not require lengthy degassing and can be adequately circulated andready for sonication in approximately 10 minutes.
Sonication of the samples is quick and easy. Using the touchscreen user interface, researchers
are able to specify unique sonication parameters for each column of the 96-well plate, enablingprocessing of many sample types for many different applications in the same microplate.
Most runs are complete within 10-30 minutes, ensuring that sample sonication will not be thebottleneck for your high-throughput applications.

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4Technical Specifications:
Dimensions (h, d, w)

45 cm x 59 cm x 34 cm (17.7 in x 23 in x 13 in)

Weight23 kg (50.7 lbs)

Power Requirements

100-240 VAC, 50-60Hz, 6 A max. at 115 VAC, 700 W

Operating Environment

15°C to 25°C (59°F to 77°F), max. 85% relative humidity

Storage Temperature

5°C to 25°C (41°F to 77°F)

EMC

Complies with EN IEC 61326-1, “Electrical equipment for measurement, control
and laboratory use - EMC requirements - Part 1: General requirements”,
Class A. Complies with FCC Part 15 Class A and FCC part 18 radio emissions
requirement for the USA and ICES-001 and ICES-003 for Industry Canada.
Complies with EU EMC Directive 2014/30/EU.
Additional information on page 20

FCC & IC Statement

Additional information on page 20

Safety Certification

UL Listing - certified to comply with UL #61010-1, 3rd Edition cUL
Listing - certified to comply with CAN/CSA C222.2 No.
61010-1-12, 3rd edition.
IEC 61010-2-081 . Particular requirements for automatic and semi-automatic
laboratory equipment for analysis and other purposes
CE Mark - complies with EN/IEC 61010-1 3rd edition.
Under Ul file # E513812-D1000

Operating System

User interface, software and processors are fully integrated into the
instrument.

Chiller

Chiller is fully integrated into the instrument.

Sample Processing Capacity

Sample processing uses round bottom 96-well microplates (Corning Cat. No.
3799), 200 µL per well

Recommended Batch Size

1 to 96

Applications

DNA Shearing
RNA Shearing
Chromatin Shearing
Protein Extraction

Included Accessories:

a. Drain Tube
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b. Shipping Cap
5

PIXUL™ Multi-Sample Sonicator Exterior Components
1
2
3
4
5
6
7

1. Main Power Button: Press to turn on the PIXUL instrument. Power switch on back side of the
PIXUL instrument must be turned on first.
2. Touchscreen User Interface: Will initiate once main power button is pressed. Use thetouchscreen to circulate the PIXUL Coupling Fluid, select sonication parameters, monitor
Coupling Fluid temperature, and monitor the time remaining for the run.
3. Exterior Lid: Lift to install sample plate. Lid must remain down during sonication run.
4. Pressure Distribution Plate Cover: Sits directly on top of the sample plate and is secured
down with the latching mechanism.
5. Latching Mechanism: Once the sample plate has been placed with well A1 in the upper left
corner and covered with the pressure distribution plate cover, push both levers with yourthumbs or fingers to engage the latches and secure the plate prior to closing the exterior lid.
6. Coupling Fluid Reservoir: Lift cap to fill reservoir with PIXUL Coupling Fluid (approximately
0.5 L capacity). Add Coupling Fluid periodically to maintain the minimum level (about one
inch below the top of the reservoir). Drain old Coupling Fluid and add new Coupling Fluid
every two months.
7. Drain: To drain PIXUL Coupling Fluid from the Coupling Fluid reservoir, ensure that no plate is
installed. Then, connect the drainage tubing to the drain. Coupling Fluid should begin to flow.

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Installing the PIXUL Multi-Sample Sonicator
The following instructions detail the installation procedure for the PIXUL Multi-Sample Sonicator.
Only attempt to install this instrument after reading these instructions.
No special tools are required for installation.
The PIXUL instrument is intended for indoor use, and the power plug must be grounded.
Place the PIXUL instrument on a level, non-slip surface with sufficient load bearing capacity. Do
not place anything heavy on the PIXUL instrument.
Do not cover the ventilation openings. Provide at least 20 cm of clearance to allow proper
airflow. Toxic vapors can be produced depending on the type of operation. Ensure sufficient
extraction of the vapors.
1. Open the boxes and cut the shipping straps. Remove the molded styrofoam packaging,protective clear wrapping, and any tape securing moving parts. Inspect the instrument andaccessories immediately after delivery for completeness and transport damage.
2. Place the PIXUL instrument on a bench. Always make sure the PIXUL is on a level surface.
3. Remove the Shipping Cap and save it. Fill the reservoir of the PIXUL instrument withapproximately 0.5 liters of PIXUL Coupling Fluid. The fluid level should reach about an inch
below the reservoir top. If you accidentally overfill the reservoir, wipe up any spilled Coupling
Fluid and suction Coupling Fluid out of reservoir until it reaches the appropriate level. Coverthe reservoir with the Black Running Cap.
4. Plug the power cord into the back side of the PIXUL instrument and the wall outlet.

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Installing Your Sample Plate

Diagram of Features.

Grasp lid by Lifting Handle toremove Pressure Distribution
Plate Cover.
Do not pry the levers or latch
up, the latching mechanism
will disengage when the Lift
Handle is lifted.

Lift to Remove.

Insert your plate.

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Warning: A 96-Well PIXUL Plate (cat. no. 53139) should be mounted and secured prior toattempting to circulate the PIXUL Coupling Fluid. Load your samples into the 96-Well PIXUL Platein the same orientation as will be indicated on the instrument touchscreen. Any wells lacking
sample in the columns being sonicated MUST be filled with liquid (water or buffer).

Be sure to seal the plate well with an adhesive plate seal to prevent the samples from spilling.
Coupling Fluid should be circulated and allowed to cool to approximately 15°C prior to initiating
sample processing.

Place the Pressure
Distribution Plate Cover on
top of Sample Plate.

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Engage Latching Mechanism
by pressing on both Levers
with your thumbs or fingers
to engage latch. There is no
audible click.
Close the Exterior Lid. If thePressure Distribution Plate
Cover is improperly seated, theExterior Lid will not close.

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Operating the PIXUL Multi-Sample Sonicator
1. Ensure that the PIXUL Coupling Fluid level is about an inch (2.5 cm) below the reservoir top. Do
not overfill.
2. Switch on the power switch on the back side of the PIXUL instrument.
3. Press the main power button on the front side of the PIXUL instrument. The touchscreen will
start initializing.
4. Load your samples in the 96-well PIXUL plate (cat. No. 53139). 100 µl sample volume perwell is optimal. Be sure to keep the outside bottom of the plate clean and free of lint orother debris. Load the sample-containing 96-Well PIXUL Plate (cat. no. 53139) into the PIXUL
instrument. Lift the external lid, place the plate with well A1 in the upper left corner, secure
down the pressure distribution lid on top of the plate with plate-securing rods, and close theexternal lid.

Coupling Buffertemperature(Step 5)

Column selector(Step 6)
Preset selectors(Step 7)

Sonication
parameters(Step 7)

Add/Delete
buttons(Step 7)

Start button(Step 8)Circulate button(Step 5)

5. On the touchscreen, press Circulate to initiate PIXUL Coupling Fluid cooling. You cannot start
the sonication run with out circulation active. You can monitor Coupling Fluid temperature in
the upper right hand corner of the touchscreen.
6. On the touchscreen, select the plate columns for which you would like to set sonication
parameters. Columns selected together will be outlined in the same color.
7. On the left side of the touchscreen, you can use the left and right arrows to select from saved
presets of sonication parameters. You can also use the add and delete buttons to add or
remove a row of process settings.
Adjust the following parameters (See Appendix, Section A for further details):
Pulse: The number of 2 MHz cycles per pulse
PRF: Pulse Repetition Frequency; the kHz frequency of pulse repetitions

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Process Time: Time a given column is actively driven. Process timers for all columns run
simultaneously, so the total run time for the entire plate is equal to the time of the column(s)chosen to have the longest process time. For example, a plate with the following columnassociated process times will take a total of 21 minutes:
Columns

Process Time1, 2 and 4

18 minutes

3, 6, 9, 10 and 12

12 minutes

5, 7 and 8

21 minutes

11

0 minutes

Burst Rate: The frequency with which the burst (a set of pulses) transitions from one column tothe next; this parameter is always the same for all columns. We recommend using the following
parameter specifications as a starting point, and adjusting Process Time to optimize for your specificsample and application:
Note: The software will not allow settings that could damage the transducers and the upper limits
are a maximum Pulse of 50 or a maximum PRF of 1.00. We recommend a minimum Burst Rate of
20.00 Varying the Process Time is typically the only parameter that needs adjusting, with longer
Time needed for difficult samples such as adipose tissue.
8. Once the PIXUL Coupling Fluid has reached approximately 15°C, press Start on thetouchscreen. The time to completion will appear in the top left hand corner of the touchscreen.
9. Once the run has completed, open the external lid. PIXUL Coupling Fluid will drain fromunderneath the sample plate for the next few seconds.
10. Unload the sample plate by lifting the Pressure Distribution Plate Cover by the Lift Handle andsimply pulling up.
11. To turn off the PIXUL instrument, press the main power button on the front side of the PIXUL
instrument and switch the power switch off on the back side of the PIXUL instrument.
Sonication
Parameter

DNA**(Cells & Tissue)

Chromatin**(Cells & Tissue)

DNA/RNA**(Purified)Protein**(Cells & Tissue)

Pulse [N]

50

50

50

50

PRF [kHz]

1.00

1.00

1.00

1.00

Process Time

30:00

30:00

10:00 – 30:00

1.00 –2.00

Burst Rate [Hz]

20.00

20.00

20.00

20.00

*Labile marks, like phosphorylated epitopes, may be preserved better by discontinuous
sonication (e.g. rather than 30 minutes, 4 rounds of 4-6 minutes each, where the PIXUL
Coupling Fluid is allowed to circulate and cool between runs).
**Please see our Quick Guides for additional details on sonication recommendations.

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Maintenance• Before all maintenance work, you should ensure that decontamination of the device has
been performed if it came into contact with hazardous materials.
• Ensure all components of the PIXUL instrument are at room temperature before touchingthem.
• Before and after each use, wipe down the plate loading area with a damp cloth, and thendry. You may remove the external lid to aid in this cleaning.
• At daily intervals, inspect the drain plug by visual inspection from the outside.
• At monthly intervals, inspect the PIXUL Coupling Fluid, and clean the touchscreen withwater and detergent. Do not use acetone or solvents as these may cause damage.
• At bimonthly intervals, PIXUL Coupling Fluid should be replaced.
To drain Coupling Fluid, attach the drain hose to the drain on the front of the instrument andensure that no plate is loaded into the instrument. Once the hose is attached, the Coupling
Fluid will begin to flow. Be ready to capture draining Fluid in a waste collection container.
• When replacing PIXUL Coupling Fluid read and retain the SDS documentation whichaccompanies the fluid
Removal of equipment from use for repair or disposal
To ship the PIXUL, the Coupling Fluid must be drained, and the Shipping Cap that came with
the instrument must be used as the cover for the Coupling Fluid Reservoir. There also must bea microplate in place and secured with the Latches engaged on the Pressure Distribution Plate
Cover.
• Refer to the supplied SDS for further information on the Coupling fluid.
• Coupling fluid should be disposed of according to local regulations.
Disassembly Instructions
For WEEE materials and components removal procedures please contact Active Motif for
instructions on how to return the instrument to the factory. Contact information is provided on the
cover page of this document.

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Tools Required
This equipment is built with metric hardware.
• Set of metric Allen wrenches• Set of metric Torx wrenches• Set of metric socket wrenches• Set of standard and positron screw drivers
Material shipped into the EU are RoHS compliant 5/6 and are to be recycled according toregulatory requirements.
The transducer contains Lead and must be disposed of accordingly

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Touchscreen Messages and Errors
Checking for microplate/No microplate detected – The PIXUL instrument ensures that a plate isloaded prior to commencing Coupling Fluid circulation or sonication run.
Removing fluid from microplate area – The PIXUL instrument automatically drains Coupling
Fluid when the external lid is opened.
Unable to start processing. No columns are enabled. – The PIXUL instrument requires thePulse, PRF, Process Time, and Burst Rate to be set for at least one column before the sonication
run will initiate.
Circulation must be enabled before starting process. – On the touchscreen, Circulate must bepressed and the Coupling Fluid allowed to circulate and cool before processing will initiate.
Lid is open. Please close lid to continue. – The external lid must be shut before processing will
initiate.
Low pressure – The pressure of the Coupling Fluid is insufficient to initiate a sonication run.
Please stop the run, power off, remove plate, close lid, and contact Active Motif. DO NOT use
PIXUL before we respond.
Touchscreen Messages:• Unable to start processing. No columns are enabled• Circulation must be enabled before starting process.
• Unable to communicate with device. Power off and on the system.
• Lid is open. Close lid to continue.
• Input parameter was invalid. Nearest valid value will automatically be selected.
• Power off and on the system.
• Checking for microplate.
• Removing fluid from microplate area.
• Low Pressure. pressure1 = 123 pressure2 = 123 If you see this error, please stop the run,power off, remove plate, close lid, and contact Active Motif. DO NOT use PIXUL before we
respond.
• No microplate detected pressure1 = 123, pressure 2 = 123• Temperature 239°C. Contact Active Motif for service instructions.

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References
1.
2.
3.
4.
5.

Bomsztyk, K., et al. (2019) Nucleic Acids Research 47(12): e69.
Kanter, J.E., et al. (2019) J. Clin. Invest. 129(10):4165-4179
Levy, S., et al. (2022) Cell Reports 38, 110457
Chapin, N., et al. (2022) Communications Biology 5:596
Hopf, A., et al. (2022) Bioengineering (Basel) 9(9):412

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Appendix
Section A. PIXUL Sonication Parameters Guide

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17Section B. Troubleshooting Guide

Problem/question

Possible cause

Recommendation

Instrument will notturn on.

No power is being
supplied to the unit.

Check that the power cord is securely plugged into boththe PIXUL instrument and wall plug.

Unit hasn’t been
properly turned on.

Ensure that both the power switch on the back side andthe main power switch on the front side of the PIXUL
instrument are both turned on.

Sonication run will notstart.

Coupling Fluid is not
circulating.

Check to make sure that the Coupling Fluid has started
circulating.

Samples do notsonicate as expected.

Plate is installed
incorrectly.

Ensure well A1 of the plate is placed in the upper left
corner.

Samples areoverheating.

Monitor the Coupling Fluid temperature and ensure thatit does not exceed 35°C during sonication. Reduce thePulse and/or PRF values if necessary.

Samples are
not diluted inappropriate
sonication buffer.

Ensure that your sample is diluted in the recommended
sonication buffer, as specified in Quick Guides and User
Manuals. Consider running a positive control sample,
available from Active Motif.

Clogged filter.

Please stop the run, power off, remove plate, close lid,
and contact Active Motif. DO NOT use PIXUL before we
respond. DO NOT continue to run PIXUL bypassing themessage under any circumstances.

Low Pressure Error.

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18Section C. WEEE Statement

This symbol on the product(s) and/or accompanying documents means that used electrical andelectronic equipment (WEEE) should not be mixed with general household waste.
Disposing of this product correctly will help save valuable resources and prevent any potential
negative effects on human health and the environment, which could otherwise arise frominappropriate waste handling.
Penalties may be applicable for incorrect disposal of this waste, in accordance with your national
legislation.
For professional users in the European Union
If you wish to discard electrical and electronic equipment (EEE), please contact your dealer or
supplier for further information.
For disposal in countries outside of the European Union
This symbol is only valid in the European Union (EU). If you wish to discard this product, pleasecontact your local authorities or dealer and ask for the correct method of disposal.

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19Section D. FCC & IC Statement

This device complies with Part 15 and Part 18 of the FCC Rules. Operation is subject to thefollowing two conditions: (1) This device may not cause harmful interference, and (2) thisdevice must accept any interference received, including interference that may cause undesired
operation.
This product may cause interference to radio equipment and should not be installed near
maritime safety communications equipment or other critical navigation or communicationequipment operating between 0.45-30 MHz.
This equipment generates, uses and can radiate radio frequency energy and, if not installed
and used in accordance with the instructions, may cause harmful interference to radio
communications. However, there is no guarantee that interference will not occur in a particularinstallation. If this equipment does cause harmful interference to other equipment , which canbe determined by turning the equipment off and on, the user is encouraged to try to correct theinterference by one or more of the following measures:—Reorient or relocate the receiving antenna. —Increase the separation
between the equipment and receiver.
—Connect the equipment into an outlet on a circuit different from that to which
the receiver is connected.
—Consult the factory and other product manufacturer or an experienced
engineer for help.

Additional information on EMC for CanadaThis ISM device complies with Canadian ICES-001
Cet appareil ISM est conforme à la norme NMB-001 du Canada.
This Class A device complies with Canadian ICES-003
Cet Clase A appareil est conforme à la norme NMB-003 du Canada.

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20Section E. Icon Legend
Icon

Description
On (Power)
Off (Power)
On or partial off
Alternating current
Protective Conductor Terminal
Earth (ground) terminal
Operating Instructions
Caution, consult user guide
Manufacturer
Model Number
Catalog Number
Serial Number
Do not dispose of in trash
Biological risks

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21

Technical Services
If you need assistance at any time, please call or send an e-mail to Active Motif Technical Service
at one of the locations listed below.

Active Motif North America
Toll free:Direct:Fax:
E-mail:Active Motif Europe
UK Free Phone:France Free Phone:
Germany Free Phone:Direct:Fax:
E-mail:877.222.9543
760.431.1263
760.431.1351
tech_service@activemotif.com
0800/169 31 47
0800/90 99 79
0800/181 99 10+32 (0)2 653 0001
+32 (0)2 653 0050
eurotech@activemotif.com

Active Motif Japan
Direct: +81 (0)3 5225 3638
Fax: +81 (0)3 5261 8733
E-mail: japantech@activemotif.com
Active Motif China
Direct: (86)-21-20926090
Cell Phone: 18521362870
E-mail: techchina@activemotif.com

Visit Active Motif online at activemotif.com

activemotif.com

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