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Seizure Disorders - What Is a Seizure? Seizures are a cardinal feature of epilepsy. Seizures are a manifestation in or from the brain that can best be described as a brief disruption in normal brain activity. This disruption then leads to an array of physiological changes that occur within the brain and can manifest themselves in observable behavioral changes. In most cases, seizure activity is rather benignand self-limited, but in rare cases it can result in significant damage or even death. Seizures are one of the most common clinical manifestations of epilepsy. Approximately 1% to 2% of Americans will experience seizures at some point during their lifetimes. But seizures are much more common in developing countries where epilepsy is a significant public health problem. This is a concise overview ofwhat seizure disorders are and their varied etiologies. It also discusses the signs, symptoms, and complications of seizures. In epileptic seizures, patients find themselves experiencing abnormal electrical discharges from the brain that cause them to lose control over muscle movements. The generalized form of epilepsy is characterized by brief but recurrent episodes that occur several times each day fordays or weeks at a time. In addition to brief episodes, there can be a number of prolonged periods – sometimes months – during which the patient experiences no seizures at all. Partial or focal seizures are limited to a small part of the brain, producing alterations of sensation, perception, thought, language function, or movement. The first step in diagnosing whether an individual is suffering fromseizure disorders is to conduct a medical history interview that focuses on personal and family health history. This would include asking about the occurrence of febrile seizures during childhood. A detailed medical examination would be performed including a complete neurological exam plus EEG, magnetic resonance imaging (MRI), neuropsychological evaluation and other tests as needed.Thediagnostic criteria for seizure disorders are defined by the International Classification of Diseases (ICD 10) and the Diagnostic and Statistical Manual of Mental Disorders (DSM IV).
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