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Pdfl Political Science S R Myneni Pdfl Political Science S R Myneni Pdfl.Stay current with ourdaily newsflash. Dauphin County Man Charged With Fraud Source: NJ.com Posted on 12 Sep
2010 A 25-year-old Dauphin County man has been charged with 12 counts of fraud and theftfollowing an investigation by the Burlington County Prosecutor's Office and the U.S. Attorney'sOffice. Dmitri Shirokhov, of Warrington, was charged with two counts of theft by deception, ninecounts of theft by unlawful taking, a third-degree crime, and four counts of theft by failure to makerequired disposition of property belonging to the United States. According to court documents,
Shirokhov took at least $3,000 in gift cards and prepaid debit cards from the Sears and Clearwater
branches of Kohl's in Plainsboro in May 2008. Shirokhov was released on $45,000 cash bail. If
convicted, he faces a maximum sentence of 25 years in state prison.Inhibition of phosphodiesterase
10A by PDE10A antisense oligodeoxynucleotides promotes Cl- currents and posttranscriptional
inactivation in cultured hippocampal neurons. The Cl(-) channel family of voltage-gated ionchannels (VGICs) play a key role in the regulation of neuronal excitability. In particular, theencoded isoform, ClC-3, confers the majority of the late-phase current in hippocampal neurons.
ClC-3 is an integral membrane protein composed of Cl(-) channel and regulatory domains. One
important mechanism for downregulation of VGICs is the interaction with regulatory proteins, inparticular PDZ (SCL9, -3, 2, and 3) and SH3 domain-containing (SIP1, AKAP79, and PDZK1)
proteins. To understand the molecular mechanisms of ClC-3 downregulation, we transfected rat
hippocampal neurons with ClC-3, along with SIP1, and examined how ClC-3 expression is1/2

affected by SIP1 in co-transfected cells. A single exposure to SIP1 led to the translocation of ClC-3
from the plasma
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Political Science S R Myneni Pdfl