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Higashi M, Ishikawa C, Yu J, Toyoda A, Kawana H, Kurokawa K, Matsuda M,Kitagawa M, Harigaya K. Human Mena associates with Rac1 small GTPase inglioblastoma cell lines. PLoS ONE. 4(3):e4765. Epub 2009 Mar 11, 2009.
Hayakawa S, Mori M, Okuta A, Kamegawa A, Fujiyoshi Y, Yoshiyama Y, Mitsuoka K,Ishibashi K, Sasaki S, Hattori T, Kuwabara S. Neuromyelitis optica andanti-aquaporin-4 antibodies measured by an enzyme-linked immunosorbent assay. JNeuroimmunol 196: 181-7, 2008.
Ito K, Arai K, Yoshiyama Y, Kashiwado K, Sakakibara Y, Hattori T. Astrocytic tau
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ㄆ▱⑕ࡢ⌮ゎ㹼࢔ࣝࢶࣁ࢖࣐࣮ᆺㄆ▱⑕ࢆ୰ᚰ࡟➨  ᅇ᪫ᕷࢡࣜࢽ࢝ࣝ࢝ࣥࣇ࢓ࣞࣥࢫࢭ࣑ࢼ࣮㸦ㅮ⩦఍㸧  ᪫ᕷྜྷᒣᐜṇㄆ▱⑕ࡢ㚷ู㹼ཎᅉ⑌ᝈࢆࡳࡁࢃࡵࡿ⸆≀⒪ἲ࡜࢖ࣥࣇ࢛࣮࣒ࢻࢥࣥࢭࣉࢺ㹼࿌▱࡜ἲไᗘ➨  ᅇ᪫ᕷࢡࣜࢽ࢝ࣝ࢝ࣥࣇ࢓ࣞࣥࢫࢭ࣑ࢼ࣮㸦ㅮ⩦఍㸧  ᪫ᕷྜྷᒣᐜṇㄆ▱⑕ Ẽ࡙ࡁࡢࣉࣟࢭࢫ㹼ࡑࡢࢧ࢖ࣥࢆぢ㏨ࡉ࡞࠸ࡓࡵ࡟
ㄆ▱⑕ࡢ⌮ゎ㹼࢔ࣝࢶࣁ࢖࣐࣮ᆺㄆ▱⑕ࢆ୰ᚰ࡟➨  ᅇ໳ᔢᕷࢡࣜࢽ࢝ࣝ࢝ࣥࣇ࢓ࣞࣥࢫࢭ࣑ࢼ࣮  ໳ᔢᕷྜྷᒣᐜṇ⸆≀⒪ἲ࡜࢖ࣥࣇ࢛࣮࣒ࢻࢥࣥࢭࣉࢺ㹼฼⏝⪅ᮏ఩ࡢࢣ࢔ࢆ⪃࠼ࡿᆅᇦࢣ࢔࢝ࣥࣇ࢓ࣞࣥࢫࡢᐇ㊶㹼ࣔࢹࣝࢣ࣮ࢫࡢ᳨ウ➨  ᅇ᪫ᕷࢡࣜࢽ࢝ࣝ࢝ࣥࣇ࢓ࣞࣥࢫࢭ࣑ࢼ࣮㸦ㅮ⩦఍㸧 ᪫ᕷྜྷᒣᐜṇㄆ▱⑕ࡢ㚷ู㹼ཎᅉ⑌ᝈࢆࡳࡁࢃࡵࡿ⸆≀⒪ἲ࡜࢖ࣥࣇ࢛࣮࣒ࢻࢥࣥࢭࣉࢺ㹼࿌▱࡜ἲไᗘ➨  ᅇ໳ᔢᕷࢡࣜࢽ࢝ࣝ࢝ࣥࣇ࢓ࣞࣥࢫࢭ࣑ࢼ࣮  ໳ᔢᕷྜྷᒣᐜṇㄆ▱⑕ Ẽ࡙ࡁࡢࣉࣟࢭࢫ㹼ࡑࡢࢧ࢖ࣥࢆぢ㏨ࡉ࡞࠸ࡓࡵ࡟ㄆ▱⑕ࡢ⌮ゎ㹼࢔ࣝࢶࣁ࢖࣐࣮ᆺㄆ▱⑕ࢆ୰ᚰ࡟➨㸯ᅇ㤶ྲྀ㒆ᕷࢡࣜࢽ࢝ࣝ࢝ࣥࣇ࢓ࣞࣥࢫࢭ࣑ࢼ࣮ ㅮ⩦఍  బཎᕷྜྷᒣᐜṇࠕ≀ᛀࢀࠖࡣㄆ▱⑕ࡢጞࡲࡾ㸽㹼㍍ᗘㄆ▱ᶵ⬟㞀ᐖ࡜࢔ࣝࢶࣁ࢖࣐࣮⑓ᡂ⏣ᕷẸබ㛤ㅮᗙ  ᡂ⏣ᕷྜྷᒣᐜṇࣞࣅ࣮ᑠయᆺㄆ▱⑕༓ⴥᕷ་ᖌ఍ㄆ▱⑕◊✲఍⑕౛᳨ウ఍ㅮ₇  ༓ⴥᕷྜྷᒣᐜṇ⸆≀⒪ἲ࡜࢖ࣥࣇ࢛࣮࣒ࢻࢥࣥࢭࣉࢺ㹼฼⏝⪅ᮏ఩ࡢࢣ࢔ࢆ⪃࠼ࡿᆅᇦࢣ࢔࢝ࣥࣇ࢓ࣞࣥࢫࡢᐇ㊶㹼ࣔࢹࣝࢣ࣮ࢫࡢ᳨ウ➨  ᅇ໳ᔢᕷࢡࣜࢽ࢝ࣝ࢝ࣥࣇ࢓ࣞࣥࢫࢭ࣑ࢼ࣮  ໳ᔢᕷྜྷᒣᐜṇㄆ▱⑕ࡢ⮫ᗋ࡜ࡑࡢ⫼ᬒ࡜࡞ࡿ▱㆑኱⥙ᆅ༊⑓デ㐃ᦠࢆ⪃࠼ࡿ఍  ኱⥙ⓑ㔛⏫
ྜྷᒣᐜṇㄆ▱⑕ࡢ㚷ู㹼ཎᅉ⑌ᝈࢆࡳࡁࢃࡵࡿ⸆≀⒪ἲ࡜࢖ࣥࣇ࢛࣮࣒ࢻࢥࣥࢭࣉࢺ㹼࿌▱࡜ἲไᗘ➨㸰ᅇ㤶ྲྀ㒆ᕷࢡࣜࢽ࢝ࣝ࢝ࣥࣇ࢓ࣞࣥࢫࢭ࣑ࢼ࣮㸦ㅮ⩦఍㸧 బཎᕷྜྷᒣᐜṇㄆ▱⑕ Ẽ࡙ࡁࡢࣉࣟࢭࢫ㹼ࡑࡢࢧ࢖ࣥࢆぢ㏨ࡉ࡞࠸ࡓࡵ࡟ㄆ▱⑕ࡢ⌮ゎ㹼࢔ࣝࢶࣁ࢖࣐࣮ᆺㄆ▱⑕ࢆ୰ᚰ࡟➨㸯ᅇ㖯Ꮚᕷࢡࣜࢽ࢝ࣝ࢝ࣥࣇ࢓ࣞࣥࢫࢭ࣑ࢼ࣮  㖯Ꮚᕷྜྷᒣᐜṇ⸆≀⒪ἲ࡜࢖ࣥࣇ࢛࣮࣒ࢻࢥࣥࢭࣉࢺ㹼฼⏝⪅ᮏ఩ࡢࢣ࢔ࢆ⪃࠼ࡿᆅᇦࢣ࢔࢝ࣥࣇ࢓ࣞࣥࢫࡢᐇ㊶㹼ࣔࢹࣝࢣ࣮ࢫࡢ᳨ウ➨  ᅇ㤶ྲྀ㒆ᕷࢡࣜࢽ࢝ࣝ࢝ࣥࣇ࢓ࣞࣥࢫࢭ࣑ࢼ࣮㸦ㅮ⩦఍㸧 బཎᕷྜྷᒣᐜṇㄆ▱⑕ࡢ㚷ู㹼ཎᅉ⑌ᝈࢆࡳࡁࢃࡵࡿ⸆≀⒪ἲ࡜࢖ࣥࣇ࢛࣮࣒ࢻࢥࣥࢭࣉࢺ㹼࿌▱࡜ἲไᗘ➨㸰ᅇ㖯Ꮚᕷࢡࣜࢽ࢝ࣝ࢝ࣥࣇ࢓ࣞࣥࢫࢭ࣑ࢼ࣮  㖯Ꮚᕷ'◊✲ຓᡂ㔠⋓ᚓ≧ἣྜྷᒣᐜṇᖹᡂ  ᖺᗘᩥ㒊⛉Ꮫ◊✲㈝⿵ຓ㔠 ᇶ┙◊✲(C)
ࣔࢹ࣐ࣝ࢘ࢫࢆ⏝࠸ࡓࢱ࢘࢜ࣃࢳ࣮ࡢ⑓ែᶵᗎゎ᫂ࡢ⥲ྜⓗᇶ┙◊✲ ෇E.἞㦂ᐇ᪋≧ἣ
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630 ࡢ /GRSD 㠀ే⏝ࣃ࣮࢟ࣥࢯࣥ⑓ᝈ⪅ࢆᑐ㇟࡜ࡋࡓ➨ ,,㸭,,, ┦ヨ㦂㸦㸧ࡢ⥅⥆㛗ᮇᢞ୚ヨ㦂( ࡢ➽ⴎ⦰ᛶഃ⣴◳໬⑕࡟ᑐࡍࡿ⮫ᗋ➨ ,,㸭,,, ┦ヨ㦂ཬࡧ㛗ᮇヨ㦂(1$'㸭212 ⤒⓶྾཰ᆺ〇๣  ᪥  ᅇࡢ࢔ࣝࢶࣁ࢖࣐࣮ᆺㄆ▱⑕ᝈ⪅
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681 <㸦࣓࣐ࣥࢳࣥሷ㓟ሷ㸧ࡢ࢔ࣝࢶࣁ࢖࣐࣮ᆺㄆ▱⑕ᝈ⪅࡟ᑐࡍࡿ⮫ᗋヨ㦂PJ 〇๣ᢞ୚᫬ࡢ᭹⸆≧ἣࡢ᳨ウ( ࡢࣞࣅ࣮ᑠయᆺㄆ▱⑕㸦'/%㸧ࢆᑐ㇟࡜ࡋࡓ஧㔜┣᳨ẚ㍑ヨ㦂⮫ᗋ➨ ,,┦ཬࡧ⥅⥆㛗ᮇᢞ୚ヨ㦂⮫ᗋ➨ ,, ┦
5RSLQLUROH35;5㘄ࡢ/GRSD〇๣ే⏝ࡢࣃ࣮࢟ࣥࢯࣥ⑓ᝈ⪅࡟ᑐࡍࡿ⮫ᗋホ౯$ 3KDVH  0XOWLFHQWHU 5DQGRPL]HG 'RXEOH%OLQG 3ODFHER&RQWUROOHG3DUDOOHO*URXS (IILFDF\ DQG 6DIHW\ 7ULDO RI %DSLQHX]XPDE $$%
(/1 LQ6XEMHFWV:LWK0LOGWR0RGHUDWH$O]KHLPHU'LVHDVH:KR$UH
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Disease Neuroimaging Initiative)㸦୺௵◊✲⪅ྡ㸸ᮾி኱Ꮫ ஭ཎᗣኵ㸧