MagMeDIP qPCR Kit
C02010020
C02010021
Flyleaf
Date of compilation: 2020-04-07

Bill of materials
Name of substance

Identifier

Numberof piecesClassificationacc. to GHS

Pictograms

Page

Magbeads1

3 – 10

ChIP-seq grade water2

11 – 185x MagBuffer A

1

MagBuffer B

1

29 – 36

MagBuffer C

1

37 – 44

5-mC monoclonal antibody 33D3

1

45 – 52

Methylated spike-in control

1

53 – 60

Unmethylated spike-in
control

1

61 – 68

MagWash buffer-1

1

MagWash buffer-2

1

78 – 85

DNA Isolation Buffer
(DIB)

1

86 – 93

proteinase K

2

Primer pair for meDNA
spike-in ctrl

1

103 – 110

Primer pair for unDNA
spike-in ctrl

1

111 – 118

TSH2B primer pair1

119 – 126

ChIP-seq grade GAPDHTSS primer pair1

127 – 134

GenDNA Digestion buffer1

135 – 142

GenDNA precipitant1

143 – 150

United Kingdom

DIAGENODE 000297 KIT-07

Eye Dam. 1 / H318
Aquatic Chronic 2/ H411

Eye Irrit. 2 / H319
Aquatic Chronic 3/ H412

Resp. Sens. 1 /H334

19 – 28

69 – 77

94 – 102MagMeDIP qPCR Kit
C02010020
C02010021
Flyleaf
Date of compilation: 2020-04-07

Name of substance

Identifier

Numberof piecesClassificationacc. to GHS

Pictograms

Page

GenDNA TE

1

151 – 158

GenDNA RNAse (DNAsefree)1

159 – 167

United Kingdom

DIAGENODE 000297 KIT-07

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

Magbeads
version number: GHS 1.0

date of compilation: 2020-04-07

SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1

1.2

product identifiertrade name

Magbeads

registration number (REACH)

not relevant (mixture)

relevant identified uses of the substance or mixture and uses advised against
relevant identified uses

1.3

for research use only, not for use in diagnostic ortherapeutic procedures.

details of the supplier of the safety data sheet
Diagenode SA
LIEGE SCIENCE PARK Rue du Bois Saint-Jean, 34102 Seraing
Belgium
telephone: +32 4 364 20 50
e-mail: info@diagenode.com

1.4

emergency telephone number
emergency information service+32 4 364 20 50
this number is only available during the following office hours: Mon-Fri 09:00 AM - 05:00 PM

poison centre
country

nametelephone

United Kingdom

National Poisons Information Service

111

SECTION 2: Hazards identification
2.1

classification of the substance or mixture
classification according to Regulation (EC) No 1272/2008 (CLP)
this mixture does not meet the criteria for classification in accordance with Regulation No 1272/2008/EC.

2.2

label elements
labelling according to Regulation (EC) No 1272/2008 (CLP)
not required

2.3

other hazards
results of PBT and vPvB assessment
this mixture does not contain any substances that are assessed to be a PBT or a vPvB.

SECTION 3: Composition/information on ingredients
3.1

substances
not relevant (mixture)

3.2

mixturesdescription of the mixtureThis mixture does not contain any potentially hazardous products.

United Kingdom: en

page: 1 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

Magbeads
version number: GHS 1.0

date of compilation: 2020-04-07

SECTION 4: First aid measures4.1

description of first aid measuresgeneral notes
do not leave affected person unattended. remove victim out of the danger area. keep affected person warm, still andcovered. take off immediately all contaminated clothing. in all cases of doubt, or when symptoms persist, seek medical advice. in case of unconsciousness place person in the recovery position. Never give anything by mouth.

following inhalation
if breathing is irregular or stopped, immediately seek medical assistance and start first aid actions. provide fresh air.

following skin contact
wash with plenty of soap and water.

following eye contact
remove contact lenses, if present and easy to do. Continue rinsing. irrigate copiously with clean, fresh water for at least 10
minutes, holding the eyelids apart.

following ingestionrinse mouth with water (only if the person is conscious). do NOT induce vomiting.

4.2

most important symptoms and effects, both acute and delayed
symptoms and effects are not known to date.

4.3

indication of any immediate medical attention and special treatment needed
none

SECTION 5: Firefighting measures
5.1

extinguishing media
suitable extinguishing media
water spray, BC-powder, carbon dioxide (CO2)

unsuitable extinguishing media
water jet

5.2

special hazards arising from the substance or mixture
hazardous combustion products
nitrogen oxides (NOx)

5.3

advice for firefightersin case of fire and/or explosion do not breathe fumes. co-ordinate firefighting measures to the fire surroundings. do not allow firefighting water to enter drains or water courses. collect contaminated firefighting water separately. fight fire withnormal precautions from a reasonable distance.

SECTION 6: Accidental release measures
6.1

personal precautions, protective equipment and emergency procedures
for non-emergency personnel
remove persons to safety.

for emergency responders
wear breathing apparatus if exposed to vapours/dust/spray/gases.

6.2

environmental precautions
keep away from drains, surface and ground water. retain contaminated washing water and dispose of it.

United Kingdom: en

page: 2 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

Magbeads
version number: GHS 1.0

6.3

date of compilation: 2020-04-07

methods and material for containment and cleaning up
advice on how to contain a spillcovering of drains

advice on how to clean up a spill
wipe up with absorbent material (e.g. cloth, fleece). collect spillage: sawdust, kieselgur (diatomite), sand, universal binder

appropriate containment techniques
use of adsorbent materials.

other information relating to spills and releases
place in appropriate containers for disposal. ventilate affected area.

6.4

reference to other sections
hazardous combustion products: see section 5. personal protective equipment: see section 8. incompatible materials: seesection 10. disposal considerations: see section 13.

SECTION 7: Handling and storage
7.1

precautions for safe handlingrecommendations- measures to prevent fire as well as aerosol and dust generation
use local and general ventilation. use only in well-ventilated areas.

advice on general occupational hygiene
wash hands after use. do not eat, drink and smoke in work areas. remove contaminated clothing and protective equipment
before entering eating areas. never keep food or drink in the vicinity of chemicals. never place chemicals in containers thatare normally used for food or drink. keep away from food, drink and animal feedingstuffs.

7.2

conditions for safe storage, including any incompatibilities
control of effects
protect against external exposure, such as
frost

7.3

specific end use(s)see section 16 for a general overview.

SECTION 8: Exposure controls/personal protection
8.1

control parameters
this information is not available.

8.2

exposure controls
appropriate engineering controls
general ventilation.

individual protection measures (personal protective equipment)eye/face protection
wear eye/face protection.

United Kingdom: en

page: 3 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

Magbeads
version number: GHS 1.0

date of compilation: 2020-04-07

skin protection- hand protection
wear suitable gloves. chemical protection gloves are suitable, which are tested according to EN 374. check leak-tightness/
impermeability prior to use. in the case of wanting to use the gloves again, clean them before taking off and air them well.
for special purposes, it is recommended to check the resistance to chemicals of the protective gloves mentioned above together with the supplier of these gloves.

- other protection measurestake recovery periods for skin regeneration. preventive skin protection (barrier creams/ointments) is recommended. wash
hands thoroughly after handling.

respiratory protection
in case of inadequate ventilation wear respiratory protection.

environmental exposure controls
use appropriate container to avoid environmental contamination. keep away from drains, surface and ground water.

SECTION 9: Physical and chemical properties
9.1

information on basic physical and chemical properties
appearancephysical stateliquid (suspension)

colour

brown

odour

odourlessother safety parameters
pH (value)

not determinedmelting point/freezing point

not determined

initial boiling point and boiling range

not determinedflash point

not determined

evaporation rate

not determined

flammability (solid, gas)

not relevant, (fluid)

explosive limits

not determinedvapour pressure

not determined

density

not determinedvapour density

this information is not available

relative density

information on this property is not available

solubility(ies)not determinedpartition coefficient- n-octanol/water (log KOW)
United Kingdom: enthis information is not available
page: 4 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

Magbeads
version number: GHS 1.0

9.2

date of compilation: 2020-04-07

auto-ignition temperature

not determinedviscosity

not determined

explosive properties

none

oxidising properties

none

other information

there is no additional information

SECTION 10: Stability and reactivity
10.1

reactivity
concerning incompatibility: see below "Conditions to avoid" and "Incompatible materials".

10.2

chemical stability
the material is stable under normal ambient and anticipated storage and handling conditions of temperature and pressure.

10.3

possibility of hazardous reactions
no known hazardous reactions.

10.4

conditions to avoid
there are no specific conditions known which have to be avoided.

10.5

incompatible materials
there is no additional information.

10.6

hazardous decomposition products
reasonably anticipated hazardous decomposition products produced as a result of use, storage, spill and heating are notknown. hazardous combustion products: see section 5.

SECTION 11: Toxicological information
11.1

information on toxicological effects
test data are not available for the complete mixture.

classification procedurethe method for classification of the mixture is based on ingredients of the mixture (additivity formula).

classification according to GHS (1272/2008/EC, CLP)
this mixture does not meet the criteria for classification in accordance with Regulation No 1272/2008/EC.

acute toxicity
shall not be classified as acutely toxic.

skin corrosion/irritation
shall not be classified as corrosive/irritant to skin.

serious eye damage/eye irritation
shall not be classified as seriously damaging to the eye or eye irritant.

respiratory or skin sensitisation
shall not be classified as a respiratory or skin sensitiser.

germ cell mutagenicity
shall not be classified as germ cell mutagenic.

United Kingdom: en

page: 5 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

Magbeads
version number: GHS 1.0

date of compilation: 2020-04-07

carcinogenicity
shall not be classified as carcinogenic.

reproductive toxicity
shall not be classified as a reproductive toxicant.

specific target organ toxicity - single exposure
shall not be classified as a specific target organ toxicant (single exposure).

specific target organ toxicity - repeated exposure
shall not be classified as a specific target organ toxicant (repeated exposure).

aspiration hazard
shall not be classified as presenting an aspiration hazard.

SECTION 12: Ecological information
12.1

toxicity
shall not be classified as hazardous to the aquatic environment.

12.2

persistence and degradability
data are not available.

12.3

bioaccumulative potential
data are not available.

12.4

mobility in soil
data are not available.

12.5

results of PBT and vPvB assessment
data are not available.

12.6

other adverse effects
data are not available.

SECTION 13: Disposal considerations
13.1

waste treatment methods
sewage disposal-relevant information
do not empty into drains. avoid release to the environment. Refer to special instructions/safety data sheets.

waste treatment of containers/packagingscompletely emptied packages can be recycled. handle contaminated packages in the same way as the substance itself.

remarks
please consider the relevant national or regional provisions. waste shall be separated into the categories that can behandled separately by the local or national waste management facilities.

United Kingdom: en

page: 6 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

Magbeads
version number: GHS 1.0

date of compilation: 2020-04-07

SECTION 14: Transport information
14.1

UN numbernot subject to transport regulations

14.2

UN proper shipping namenot relevant

14.3

transport hazard class(es)

none

14.4

packing group

not assigned to a packing group

14.5

environmental hazards

non-environmentally hazardous acc. to the dangerous goods regulations

14.6

special precautions for user
there is no additional information.

14.7

transport in bulk according to Annex II of MARPOL and the IBC Codethe cargo is not intended to be carried in bulk.

Information for each of the UN Model Regulationstransport of dangerous goods by road, rail and inland waterway (ADR/RID/ADN)
not subject to ADR, RID and ADN.

International Maritime Dangerous Goods Code (IMDG)
not subject to IMDG.

International Civil Aviation Organization (ICAO-IATA/DGR)
not subject to ICAO-IATA.

SECTION 15: Regulatory information
15.1

safety, health and environmental regulations/legislation specific for the substance or mixture

15.2

Chemical Safety Assessment
chemical safety assessments for substances in this mixture were not carried out.

SECTION 16: Other informationabbreviations and acronyms
abbr.

descriptions of used abbreviations

ADN

Accord européen relatif au transport international des marchandises dangereuses par voies de navigation
intérieures (European Agreement concerning the International Carriage of Dangerous Goods by Inland Waterways)

ADR

Accord européen relatif au transport international des marchandises dangereuses par route (European Agreement concerning the International Carriage of Dangerous Goods by Road)

CLP

Regulation (EC) No 1272/2008 on classification, labelling and packaging of substances and mixtures

DGR

Dangerous Goods Regulations (see IATA/DGR)

GHS"Globally Harmonized System of Classification and Labelling of Chemicals" developed by the United Nations

IATA

International Air Transport Association

IATA/DGR

Dangerous Goods Regulations (DGR) for the air transport (IATA)ICAOInternational Civil Aviation Organization

IMDG

International Maritime Dangerous Goods CodeUnited Kingdom: en

page: 7 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

Magbeads
version number: GHS 1.0

date of compilation: 2020-04-07

abbr.

descriptions of used abbreviations

MARPOLInternational Convention for the Prevention of Pollution from Ships (abbr. of "Marine Pollutant")

PBT

Persistent, Bioaccumulative and Toxic

REACH

Registration, Evaluation, Authorisation and Restriction of Chemicals

RID

Règlement concernant le transport International ferroviaire des marchandises Dangereuses (Regulations concerning the International carriage of Dangerous goods by Rail)vPvB

Very Persistent and very Bioaccumulative

key literature references and sources for data
Regulation (EC) No 1272/2008 on classification, labelling and packaging of substances and mixtures. Regulation (EC) No.
1907/2006 (REACH), amended by 2015/830/EU.
transport of dangerous goods by road, rail and inland waterway (ADR/RID/ADN). International Maritime Dangerous Goods
Code (IMDG). Dangerous Goods Regulations (DGR) for the air transport (IATA).

classification procedurephysical and chemical properties: the classification is based on tested mixture.
health hazards, environmental hazards: the method for classification of the mixture is based on ingredients of the mixture(additivity formula).

disclaimer
this information is based upon the present state of our knowledge. this SDS has been compiled and is solely intended for thisproduct.

United Kingdom: en

page: 8 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

ChIP-seq grade waterversion number: GHS 2.0
replaces version of: 2019-11-22 (GHS 1)

revision: 2019-12-23

SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1

1.2

product identifier
identification of the substance

ChIP-seq grade water

registration number (REACH)

this information is not available

CAS number

7732-18-5

relevant identified uses of the substance or mixture and uses advised against
relevant identified uses

1.3

for research use only, not for use in diagnostic ortherapeutic procedures.

details of the supplier of the safety data sheet
Diagenode SA
LIEGE SCIENCE PARK Rue du Bois Saint-Jean, 34102 Seraing
Belgium
telephone: +32 4 364 20 50
e-mail: info@diagenode.com

1.4

emergency telephone number
emergency information service+32 4 364 20 50
this number is only available during the following office hours: Mon-Fri 09:00 AM - 05:00 PM

poison centre
country

nametelephone

United Kingdom

National Poisons Information Service

111

SECTION 2: Hazards identification
2.1

classification of the substance or mixture
classification according to Regulation (EC) No 1272/2008 (CLP)
this substance does not meet the criteria for classification in accordance with Regulation No 1272/2008/EC.

2.2

label elements
labelling according to Regulation (EC) No 1272/2008 (CLP)
not required

2.3

other hazards
results of PBT and vPvB assessment
according to the results of its assessment, this substance is not a PBT or a vPvB.

United Kingdom: en

page: 1 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

ChIP-seq grade waterversion number: GHS 2.0
replaces version of: 2019-11-22 (GHS 1)

revision: 2019-12-23

SECTION 3: Composition/information on ingredients
3.1

substancesname of substance

ChIP-seq grade water

identifiers
CAS No7732-18-5

molecular formula

H2O

molar mass

18.02 g/mol

SECTION 4: First aid measures4.1

description of first aid measuresgeneral notes
do not leave affected person unattended. remove victim out of the danger area. keep affected person warm, still andcovered. take off immediately all contaminated clothing. in all cases of doubt, or when symptoms persist, seek medical advice. in case of unconsciousness place person in the recovery position. Never give anything by mouth.

following inhalation
if breathing is irregular or stopped, immediately seek medical assistance and start first aid actions. provide fresh air.

following skin contact
wash with plenty of soap and water.

following eye contact
remove contact lenses, if present and easy to do. Continue rinsing. irrigate copiously with clean, fresh water for at least 10
minutes, holding the eyelids apart.

following ingestionrinse mouth with water (only if the person is conscious). do NOT induce vomiting.

4.2

most important symptoms and effects, both acute and delayed
symptoms and effects are not known to date.

4.3

indication of any immediate medical attention and special treatment needed
none

SECTION 5: Firefighting measures
5.1

extinguishing media
suitable extinguishing media
water spray, alcohol resistant foam, BC-powder, carbon dioxide (CO2)

unsuitable extinguishing media
water jet

5.2

special hazards arising from the substance or mixture

5.3

advice for firefightersin case of fire and/or explosion do not breathe fumes. co-ordinate firefighting measures to the fire surroundings. do not allow firefighting water to enter drains or water courses. collect contaminated firefighting water separately. fight fire withnormal precautions from a reasonable distance.

United Kingdom: en

page: 2 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

ChIP-seq grade waterversion number: GHS 2.0
replaces version of: 2019-11-22 (GHS 1)

revision: 2019-12-23

SECTION 6: Accidental release measures
6.1

personal precautions, protective equipment and emergency procedures
for non-emergency personnel
remove persons to safety.

for emergency responders
wear breathing apparatus if exposed to vapours/dust/spray/gases.

6.2

environmental precautions
keep away from drains, surface and ground water. retain contaminated washing water and dispose of it.

6.3

methods and material for containment and cleaning up
advice on how to contain a spillcovering of drains

advice on how to clean up a spill
wipe up with absorbent material (e.g. cloth, fleece). collect spillage: sawdust, kieselgur (diatomite), sand, universal binder

appropriate containment techniques
use of adsorbent materials.

other information relating to spills and releases
place in appropriate containers for disposal. ventilate affected area.

6.4

reference to other sections
personal protective equipment: see section 8. incompatible materials: see section 10. disposal considerations: see section
13.

SECTION 7: Handling and storage
7.1

precautions for safe handlingrecommendations- measures to prevent fire as well as aerosol and dust generation
use local and general ventilation. use only in well-ventilated areas.

advice on general occupational hygiene
wash hands after use. do not eat, drink and smoke in work areas. remove contaminated clothing and protective equipment
before entering eating areas. never keep food or drink in the vicinity of chemicals. never place chemicals in containers thatare normally used for food or drink. keep away from food, drink and animal feedingstuffs.

7.2

conditions for safe storage, including any incompatibilities
control of effects
protect against external exposure, such as
frost

7.3

specific end use(s)see section 16 for a general overview.

United Kingdom: en

page: 3 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

ChIP-seq grade waterversion number: GHS 2.0
replaces version of: 2019-11-22 (GHS 1)

revision: 2019-12-23

SECTION 8: Exposure controls/personal protection
8.1

control parameters
this information is not available.

8.2

exposure controls
appropriate engineering controls
general ventilation.

individual protection measures (personal protective equipment)eye/face protection
wear eye/face protection.

skin protection- hand protection
wear suitable gloves. chemical protection gloves are suitable, which are tested according to EN 374. check leak-tightness/
impermeability prior to use. in the case of wanting to use the gloves again, clean them before taking off and air them well.
for special purposes, it is recommended to check the resistance to chemicals of the protective gloves mentioned above together with the supplier of these gloves.

- other protection measurestake recovery periods for skin regeneration. preventive skin protection (barrier creams/ointments) is recommended. wash
hands thoroughly after handling.

respiratory protection
in case of inadequate ventilation wear respiratory protection.

environmental exposure controls
use appropriate container to avoid environmental contamination. keep away from drains, surface and ground water.

SECTION 9: Physical and chemical properties
9.1

information on basic physical and chemical properties
appearancephysical stateliquidcolourcolourlessodour

odourlessother safety parameters
pH (value)

not determinedmelting point/freezing point

0 °C

initial boiling point and boiling range

100 °C

flash point

not determined

evaporation rate

not determined

flammability (solid, gas)

not relevant, (fluid)

United Kingdom: en

page: 4 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

ChIP-seq grade waterversion number: GHS 2.0
replaces version of: 2019-11-22 (GHS 1)

revision: 2019-12-23

explosive limits

not determinedvapour pressure

not determined

density

not determinedvapour density

this information is not available

relative density

information on this property is not available

solubility(ies)- water solubility

miscible in any proportion

partition coefficient9.2- n-octanol/water (log KOW)

this information is not available

auto-ignition temperature

not determinedviscosity

not determined

explosive properties

none

oxidising properties

none

other information

there is no additional information

SECTION 10: Stability and reactivity
10.1

reactivity
concerning incompatibility: see below "Conditions to avoid" and "Incompatible materials".

10.2

chemical stability
the material is stable under normal ambient and anticipated storage and handling conditions of temperature and pressure.

10.3

possibility of hazardous reactions
no known hazardous reactions.

10.4

conditions to avoid
there are no specific conditions known which have to be avoided.

10.5

incompatible materials
there is no additional information.

10.6

hazardous decomposition products
reasonably anticipated hazardous decomposition products produced as a result of use, storage, spill and heating are notknown. hazardous combustion products: see section 5.

United Kingdom: en

page: 5 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

ChIP-seq grade waterversion number: GHS 2.0
replaces version of: 2019-11-22 (GHS 1)

revision: 2019-12-23

SECTION 11: Toxicological information
11.1

information on toxicological effects
classification according to GHS (1272/2008/EC, CLP)
this substance does not meet the criteria for classification in accordance with Regulation No 1272/2008/EC.

acute toxicity
shall not be classified as acutely toxic.

skin corrosion/irritation
shall not be classified as corrosive/irritant to skin.

serious eye damage/eye irritation
shall not be classified as seriously damaging to the eye or eye irritant.

respiratory or skin sensitisation
shall not be classified as a respiratory or skin sensitiser.

germ cell mutagenicity
shall not be classified as germ cell mutagenic.

carcinogenicity
shall not be classified as carcinogenic.

reproductive toxicity
shall not be classified as a reproductive toxicant.

specific target organ toxicity - single exposure
shall not be classified as a specific target organ toxicant (single exposure).

specific target organ toxicity - repeated exposure
shall not be classified as a specific target organ toxicant (repeated exposure).

aspiration hazard
shall not be classified as presenting an aspiration hazard.

SECTION 12: Ecological information
12.1

toxicity
shall not be classified as hazardous to the aquatic environment.

12.2

persistence and degradability
data are not available.

12.3

bioaccumulative potential
data are not available.

12.4

mobility in soil
data are not available.

12.5

results of PBT and vPvB assessment
data are not available.

12.6

other adverse effects
data are not available.

United Kingdom: en

page: 6 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

ChIP-seq grade waterversion number: GHS 2.0
replaces version of: 2019-11-22 (GHS 1)

revision: 2019-12-23

SECTION 13: Disposal considerations
13.1

waste treatment methods
waste treatment-relevant information
recycling/reclamation of other inorganic materials.

sewage disposal-relevant information
do not empty into drains. avoid release to the environment. Refer to special instructions/safety data sheets.

waste treatment of containers/packagingscompletely emptied packages can be recycled. handle contaminated packages in the same way as the substance itself.

remarks
please consider the relevant national or regional provisions. waste shall be separated into the categories that can behandled separately by the local or national waste management facilities.

SECTION 14: Transport information
14.1

UN numbernot subject to transport regulations

14.2

UN proper shipping namenot relevant

14.3

transport hazard class(es)

none

14.4

packing group

not assigned to a packing group

14.5

environmental hazards

non-environmentally hazardous acc. to the dangerous goods regulations

14.6

special precautions for user
there is no additional information.

14.7

transport in bulk according to Annex II of MARPOL and the IBC Codethe cargo is not intended to be carried in bulk.

Information for each of the UN Model Regulationstransport of dangerous goods by road, rail and inland waterway (ADR/RID/ADN)
not subject to ADR, RID and ADN.

International Maritime Dangerous Goods Code (IMDG)
not subject to IMDG.

International Civil Aviation Organization (ICAO-IATA/DGR)
not subject to ICAO-IATA.

SECTION 15: Regulatory information
15.1

safety, health and environmental regulations/legislation specific for the substance or mixture

15.2

Chemical Safety Assessment
no Chemical Safety Assessment has been carried out for this substance.

United Kingdom: en

page: 7 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

ChIP-seq grade waterversion number: GHS 2.0
replaces version of: 2019-11-22 (GHS 1)

revision: 2019-12-23

SECTION 16: Other information
indication of changes (revised safety data sheet)sectionformer entry (text/value)

actual entry (text/value)safety-relevant

5.1

suitable extinguishing media:
not applicablesuitable extinguishing media:
water spray, alcohol resistant foam, BC-powder, carbon dioxide (CO2)

yes

5.1

unsuitable extinguishing media:
not applicableunsuitable extinguishing media:
water jetyesabbreviations and acronyms
abbr.

descriptions of used abbreviations

ADN

Accord européen relatif au transport international des marchandises dangereuses par voies de navigation
intérieures (European Agreement concerning the International Carriage of Dangerous Goods by Inland Waterways)

ADR

Accord européen relatif au transport international des marchandises dangereuses par route (European Agreement concerning the International Carriage of Dangerous Goods by Road)CAS

Chemical Abstracts Service (service that maintains the most comprehensive list of chemical substances)

CLP

Regulation (EC) No 1272/2008 on classification, labelling and packaging of substances and mixtures

DGR

Dangerous Goods Regulations (see IATA/DGR)

GHS"Globally Harmonized System of Classification and Labelling of Chemicals" developed by the United Nations

IATA

International Air Transport Association

IATA/DGR

Dangerous Goods Regulations (DGR) for the air transport (IATA)ICAOInternational Civil Aviation Organization

IMDG

International Maritime Dangerous Goods CodeMARPOLInternational Convention for the Prevention of Pollution from Ships (abbr. of "Marine Pollutant")

PBT

Persistent, Bioaccumulative and Toxic

REACH

Registration, Evaluation, Authorisation and Restriction of Chemicals

RID

Règlement concernant le transport International ferroviaire des marchandises Dangereuses (Regulations concerning the International carriage of Dangerous goods by Rail)vPvB

Very Persistent and very Bioaccumulative

key literature references and sources for data
Regulation (EC) No 1272/2008 on classification, labelling and packaging of substances and mixtures. Regulation (EC) No.
1907/2006 (REACH), amended by 2015/830/EU.
transport of dangerous goods by road, rail and inland waterway (ADR/RID/ADN). International Maritime Dangerous Goods
Code (IMDG). Dangerous Goods Regulations (DGR) for the air transport (IATA).

disclaimer
this information is based upon the present state of our knowledge. this SDS has been compiled and is solely intended for thisproduct.

United Kingdom: en

page: 8 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

5x MagBuffer A
version number: GHS 1.0

date of compilation: 2020-04-07

SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1

1.2

product identifiertrade name

5x MagBuffer A

registration number (REACH)

not relevant (mixture)

relevant identified uses of the substance or mixture and uses advised against
relevant identified uses

1.3

for research use only, not for use in diagnostic ortherapeutic procedures.

details of the supplier of the safety data sheet
Diagenode SA
LIEGE SCIENCE PARK Rue du Bois Saint-Jean, 34102 Seraing
Belgium
telephone: +32 4 364 20 50
e-mail: info@diagenode.com

1.4

emergency telephone number
emergency information service+32 4 364 20 50
this number is only available during the following office hours: Mon-Fri 09:00 AM - 05:00 PM

poison centre
country

nametelephone

United Kingdom

National Poisons Information Service

111

SECTION 2: Hazards identification
2.1

classification of the substance or mixture
classification according to Regulation (EC) No 1272/2008 (CLP)sectionhazard class

categoryhazard class and category

hazard statement

3.3

serious eye damage/eye irritation

1

Eye Dam. 1

H318

4.1C

hazardous to the aquatic environment - chronic hazard

2

Aquatic Chronic 2

H411

for full text of abbreviations: see SECTION 16.

the most important adverse physicochemical, human health and environmental effects
spillage and fire water can cause pollution of watercourses.

2.2

label elements
labelling according to Regulation (EC) No 1272/2008 (CLP)- signal word

danger- pictograms
GHS05, GHS09

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Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

5x MagBuffer A
version number: GHS 1.0

date of compilation: 2020-04-07- hazard statements
H318
H411

causes serious eye damage.
toxic to aquatic life with long lasting effects.

- precautionary statements
P273
P280
P305+P351+P338
P310
P391
P501

avoid release to the environment.
wear protective gloves/protective clothing/eye protection/face protection.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present andeasy to do. Continue rinsing.
immediately call a POISON CENTER/doctor.
collect spillage.
dispose of contents/container to industrial combustion plant.

- hazardous ingredients for labelling
2.3

Triton X-100

other hazards
results of PBT and vPvB assessment
this mixture does not contain any substances that are assessed to be a PBT or a vPvB.

SECTION 3: Composition/information on ingredients
3.1

substances
not relevant (mixture)

3.2

mixturesdescription of the mixturename of substanceidentifier

wt%classification acc. to GHS

Triton X-100

CAS No9002-93-1≤ 10

Acute Tox. 4 / H302
Skin Irrit. 2 / H315
Eye Dam. 1 / H318
Aquatic Acute 1 / H400
Aquatic Chronic 1 / H410

EC No
618-344-0

pictograms

for full text of abbreviations: see SECTION 16.

SECTION 4: First aid measures4.1

description of first aid measuresgeneral notes
do not leave affected person unattended. remove victim out of the danger area. keep affected person warm, still andcovered. take off immediately all contaminated clothing. in all cases of doubt, or when symptoms persist, seek medical advice. in case of unconsciousness place person in the recovery position. Never give anything by mouth.

following inhalation
if breathing is irregular or stopped, immediately seek medical assistance and start first aid actions. provide fresh air.

following skin contact
wash with plenty of soap and water.

following eye contact
remove contact lenses, if present and easy to do. Continue rinsing. irrigate copiously with clean, fresh water for at least 10
minutes, holding the eyelids apart.

following ingestionrinse mouth with water (only if the person is conscious). do NOT induce vomiting.

4.2

most important symptoms and effects, both acute and delayed
symptoms and effects are not known to date.

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Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

5x MagBuffer A
version number: GHS 1.0

4.3

date of compilation: 2020-04-07

indication of any immediate medical attention and special treatment needed
none

SECTION 5: Firefighting measures
5.1

extinguishing media
suitable extinguishing media
water spray, BC-powder, carbon dioxide (CO2)

unsuitable extinguishing media
water jet

5.2

special hazards arising from the substance or mixture
hazardous combustion products
nitrogen oxides (NOx), carbon monoxide (CO), carbon dioxide (CO2)

5.3

advice for firefightersin case of fire and/or explosion do not breathe fumes. co-ordinate firefighting measures to the fire surroundings. do not allow firefighting water to enter drains or water courses. collect contaminated firefighting water separately. fight fire withnormal precautions from a reasonable distance.

SECTION 6: Accidental release measures
6.1

personal precautions, protective equipment and emergency procedures
for non-emergency personnel
remove persons to safety.

for emergency responders
wear breathing apparatus if exposed to vapours/dust/spray/gases.

6.2

environmental precautions
keep away from drains, surface and ground water. retain contaminated washing water and dispose of it. if substance hasentered a water course or sewer, inform the responsible authority.

6.3

methods and material for containment and cleaning up
advice on how to contain a spillcovering of drains

advice on how to clean up a spill
wipe up with absorbent material (e.g. cloth, fleece). collect spillage: sawdust, kieselgur (diatomite), sand, universal binder

appropriate containment techniques
use of adsorbent materials.

other information relating to spills and releases
place in appropriate containers for disposal. ventilate affected area.

6.4

reference to other sections
hazardous combustion products: see section 5. personal protective equipment: see section 8. incompatible materials: seesection 10. disposal considerations: see section 13.

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Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

5x MagBuffer A
version number: GHS 1.0

date of compilation: 2020-04-07

SECTION 7: Handling and storage
7.1

precautions for safe handlingrecommendations- measures to prevent fire as well as aerosol and dust generation
use local and general ventilation. use only in well-ventilated areas.

advice on general occupational hygiene
wash hands after use. do not eat, drink and smoke in work areas. remove contaminated clothing and protective equipment
before entering eating areas. never keep food or drink in the vicinity of chemicals. never place chemicals in containers thatare normally used for food or drink. keep away from food, drink and animal feedingstuffs.

7.2

conditions for safe storage, including any incompatibilities
control of effects
protect against external exposure, such asfrost- packaging compatibilities
only packagings which are approved (e.g. acc. to ADR) may be used.

7.3

specific end use(s)see section 16 for a general overview.

SECTION 8: Exposure controls/personal protection
8.1

control parameters
this information is not available.

8.2

exposure controls
appropriate engineering controls
general ventilation.

individual protection measures (personal protective equipment)eye/face protection
wear eye/face protection.

skin protection- hand protection
wear suitable gloves. chemical protection gloves are suitable, which are tested according to EN 374. check leak-tightness/
impermeability prior to use. in the case of wanting to use the gloves again, clean them before taking off and air them well.
for special purposes, it is recommended to check the resistance to chemicals of the protective gloves mentioned above together with the supplier of these gloves.

- other protection measurestake recovery periods for skin regeneration. preventive skin protection (barrier creams/ointments) is recommended. wash
hands thoroughly after handling.

respiratory protection
in case of inadequate ventilation wear respiratory protection.

environmental exposure controls
use appropriate container to avoid environmental contamination. keep away from drains, surface and ground water.

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Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

5x MagBuffer A
version number: GHS 1.0

date of compilation: 2020-04-07

SECTION 9: Physical and chemical properties
9.1

information on basic physical and chemical properties
appearancephysical stateliquidcolourcolourlessodour

odourlessother safety parameters
pH (value)

not determinedmelting point/freezing point

not determined

initial boiling point and boiling range

not determinedflash point

not determined

evaporation rate

not determined

flammability (solid, gas)

not relevant, (fluid)

explosive limits

not determinedvapour pressure

not determined

density

not determinedvapour density

this information is not available

relative density

information on this property is not available

solubility(ies)not determinedpartition coefficient9.2- n-octanol/water (log KOW)

this information is not available

auto-ignition temperature

not determinedviscosity

not determined

explosive properties

none

oxidising properties

none

other information

there is no additional information

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Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

5x MagBuffer A
version number: GHS 1.0

date of compilation: 2020-04-07

SECTION 10: Stability and reactivity
10.1

reactivity
concerning incompatibility: see below "Conditions to avoid" and "Incompatible materials".

10.2

chemical stability
see below "Conditions to avoid".

10.3

possibility of hazardous reactions
no known hazardous reactions.

10.4

conditions to avoid
there are no specific conditions known which have to be avoided.

10.5

incompatible materials
oxidisers

10.6

hazardous decomposition products
reasonably anticipated hazardous decomposition products produced as a result of use, storage, spill and heating are notknown. hazardous combustion products: see section 5.

SECTION 11: Toxicological information
11.1

information on toxicological effects
test data are not available for the complete mixture.

classification procedurethe method for classification of the mixture is based on ingredients of the mixture (additivity formula).

classification according to GHS (1272/2008/EC, CLP)
acute toxicity
shall not be classified as acutely toxic.

skin corrosion/irritation
shall not be classified as corrosive/irritant to skin.

serious eye damage/eye irritation
causes serious eye damage.

respiratory or skin sensitisation
shall not be classified as a respiratory or skin sensitiser.

germ cell mutagenicity
shall not be classified as germ cell mutagenic.

carcinogenicity
shall not be classified as carcinogenic.

reproductive toxicity
shall not be classified as a reproductive toxicant.

specific target organ toxicity - single exposure
shall not be classified as a specific target organ toxicant (single exposure).

specific target organ toxicity - repeated exposure
shall not be classified as a specific target organ toxicant (repeated exposure).

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Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

5x MagBuffer A
version number: GHS 1.0

date of compilation: 2020-04-07

aspiration hazard
shall not be classified as presenting an aspiration hazard.

SECTION 12: Ecological information
12.1

toxicity
toxic to aquatic life with long lasting effects.

12.2

persistence and degradability
data are not available.

12.3

bioaccumulative potential
data are not available.

12.4

mobility in soil
data are not available.

12.5

results of PBT and vPvB assessment
data are not available.

12.6

other adverse effects
data are not available.

SECTION 13: Disposal considerations
13.1

waste treatment methods
sewage disposal-relevant information
do not empty into drains. avoid release to the environment. Refer to special instructions/safety data sheets.

waste treatment of containers/packagings
it is a dangerous waste; only packagings which are approved (e.g. acc. to ADR) may be used. completely emptied packages
can be recycled. handle contaminated packages in the same way as the substance itself.

remarks
please consider the relevant national or regional provisions. waste shall be separated into the categories that can behandled separately by the local or national waste management facilities.

SECTION 14: Transport information
14.1

UN number

3082

14.2

UN proper shipping name

ENVIRONMENTALLY HAZARDOUS SUBSTANCE, LIQUID, N.O.S.

technical name (hazardous ingredients)

Triton X-100

14.3

transport hazard class(es)class

9 (environmentally hazardous)

14.4

packing group

III (substance presenting low danger)

14.5

environmental hazards

hazardous to the aquatic environment

environmentally hazardous substance (aquatic
environment)

Triton X-100

14.6

special precautions for user
provisions for dangerous goods (ADR) should be complied within the premises.

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Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

5x MagBuffer A
version number: GHS 1.0

14.7

date of compilation: 2020-04-07

transport in bulk according to Annex II of MARPOL and the IBC Codethe cargo is not intended to be carried in bulk.

Information for each of the UN Model Regulationstransport of dangerous goods by road, rail and inland waterway (ADR/RID/ADN)
UN number

3082

proper shipping name

ENVIRONMENTALLY HAZARDOUS SUBSTANCE, LIQUID, N.O.S.

class

9

classification code

M6

packing groupIII

danger label(s)9, fish and tree

environmental hazards

yes (hazardous to the aquatic environment)

special provisions (SP)274, 335, 375, 601

excepted quantities (EQ)

E1

limited quantities (LQ)

5L

transport category (TC)3tunnel restriction code (TRC)-

hazard identification No

90

Emergency Action Code

3Z

International Maritime Dangerous Goods Code (IMDG)
UN number

3082

proper shipping name

ENVIRONMENTALLY HAZARDOUS SUBSTANCE, LIQUID, N.O.S.

class

9

marine pollutant

yes (hazardous to the aquatic environment)

packing groupIII

danger label(s)9, fish and tree

special provisions (SP)274, 335, 969

excepted quantities (EQ)

E1

limited quantities (LQ)

5L

EmS

F-A, S-F

stowage category

A

United Kingdom: en

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Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

5x MagBuffer A
version number: GHS 1.0

date of compilation: 2020-04-07

International Civil Aviation Organization (ICAO-IATA/DGR)
UN number

3082

proper shipping name

Environmentally hazardous substance, liquid, n.o.s.

class

9

environmental hazards

yes (hazardous to the aquatic environment)

packing groupIII

danger label(s)9, fish and tree

special provisions (SP)A97, A158, A197

excepted quantities (EQ)

E1

limited quantities (LQ)

30 kg

SECTION 15: Regulatory information
15.1

safety, health and environmental regulations/legislation specific for the substance or mixture

15.2

Chemical Safety Assessment
chemical safety assessments for substances in this mixture were not carried out.

SECTION 16: Other informationabbreviations and acronyms
abbr.

descriptions of used abbreviations

Acute Tox.

Acute toxicity

ADN

Accord européen relatif au transport international des marchandises dangereuses par voies de navigation
intérieures (European Agreement concerning the International Carriage of Dangerous Goods by Inland Waterways)

ADR

Accord européen relatif au transport international des marchandises dangereuses par route (European Agreement concerning the International Carriage of Dangerous Goods by Road)

Aquatic Acute

Hazardous to the aquatic environment - acute hazard

Aquatic Chronic

Hazardous to the aquatic environment - chronic hazard

CAS

Chemical Abstracts Service (service that maintains the most comprehensive list of chemical substances)

CLP

Regulation (EC) No 1272/2008 on classification, labelling and packaging of substances and mixtures

DGR

Dangerous Goods Regulations (see IATA/DGR)

EC No

The EC Inventory (EINECS, ELINCS and the NLP-list) is the source for the seven-digit EC number, an identifierof substances commercially available within the EU (European Union)

EINECS

European Inventory of Existing Commercial Chemical Substances

ELINCS

European List of Notified Chemical Substances

EmS

Emergency Schedule

Eye Dam.

Seriously damaging to the eye

Eye Irrit.

Irritant to the eye

GHS"Globally Harmonized System of Classification and Labelling of Chemicals" developed by the United Nations

IATA

International Air Transport Association

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Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

5x MagBuffer A
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date of compilation: 2020-04-07

abbr.

descriptions of used abbreviations

IATA/DGR

Dangerous Goods Regulations (DGR) for the air transport (IATA)ICAOInternational Civil Aviation Organization

IMDG

International Maritime Dangerous Goods Codeindex NoThe Index number is the identification code given to the substance in Part 3 of Annex VI to Regulation (EC) No
1272/2008

MARPOLInternational Convention for the Prevention of Pollution from Ships (abbr. of "Marine Pollutant")

NLP

No-Longer Polymer

PBT

Persistent, Bioaccumulative and Toxic

REACH

Registration, Evaluation, Authorisation and Restriction of Chemicals

RID

Règlement concernant le transport International ferroviaire des marchandises Dangereuses (Regulations concerning the International carriage of Dangerous goods by Rail)Skin Corr.

Corrosive to skin

Skin Irrit.

Irritant to skinvPvB

Very Persistent and very Bioaccumulative

key literature references and sources for data
Regulation (EC) No 1272/2008 on classification, labelling and packaging of substances and mixtures. Regulation (EC) No.
1907/2006 (REACH), amended by 2015/830/EU.
transport of dangerous goods by road, rail and inland waterway (ADR/RID/ADN). International Maritime Dangerous Goods
Code (IMDG). Dangerous Goods Regulations (DGR) for the air transport (IATA).

classification procedurephysical and chemical properties: the classification is based on tested mixture.
health hazards, environmental hazards: the method for classification of the mixture is based on ingredients of the mixture(additivity formula).

list of relevant phrases (code and full text as stated in chapter 2 and 3)
code

text

H302

Harmful if swallowed.

H315

Causes skin irritation.

H318

Causes serious eye damage.

H400

Very toxic to aquatic life.

H410

Very toxic to aquatic life with long lasting effects.

H411

Toxic to aquatic life with long lasting effects.

disclaimer
this information is based upon the present state of our knowledge. this SDS has been compiled and is solely intended for thisproduct.

United Kingdom: en

page: 10 / 10

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

MagBuffer B
version number: GHS 1.0

date of compilation: 2020-04-07

SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1

1.2

product identifiertrade name

MagBuffer B

registration number (REACH)

not relevant (mixture)

relevant identified uses of the substance or mixture and uses advised against
relevant identified uses

1.3

for research use only, not for use in diagnostic ortherapeutic procedures.

details of the supplier of the safety data sheet
Diagenode SA
LIEGE SCIENCE PARK Rue du Bois Saint-Jean, 34102 Seraing
Belgium
telephone: +32 4 364 20 50
e-mail: info@diagenode.com

1.4

emergency telephone number
emergency information service+32 4 364 20 50
this number is only available during the following office hours: Mon-Fri 09:00 AM - 05:00 PM

poison centre
country

nametelephone

United Kingdom

National Poisons Information Service

111

SECTION 2: Hazards identification
2.1

classification of the substance or mixture
classification according to Regulation (EC) No 1272/2008 (CLP)
this mixture does not meet the criteria for classification in accordance with Regulation No 1272/2008/EC.

2.2

label elements
labelling according to Regulation (EC) No 1272/2008 (CLP)
not required

2.3

other hazards
results of PBT and vPvB assessment
this mixture does not contain any substances that are assessed to be a PBT or a vPvB.

SECTION 3: Composition/information on ingredients
3.1

substances
not relevant (mixture)

3.2

mixtures

United Kingdom: en

description of the mixture

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Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

MagBuffer B
version number: GHS 1.0

date of compilation: 2020-04-07

SECTION 4: First aid measures4.1

description of first aid measuresgeneral notes
do not leave affected person unattended. remove victim out of the danger area. keep affected person warm, still andcovered. take off immediately all contaminated clothing. in all cases of doubt, or when symptoms persist, seek medical advice. in case of unconsciousness place person in the recovery position. Never give anything by mouth.

following inhalation
if breathing is irregular or stopped, immediately seek medical assistance and start first aid actions. provide fresh air.

following skin contact
wash with plenty of soap and water.

following eye contact
remove contact lenses, if present and easy to do. Continue rinsing. irrigate copiously with clean, fresh water for at least 10
minutes, holding the eyelids apart.

following ingestionrinse mouth with water (only if the person is conscious). do NOT induce vomiting.

4.2

most important symptoms and effects, both acute and delayed
symptoms and effects are not known to date.

4.3

indication of any immediate medical attention and special treatment needed
none

SECTION 5: Firefighting measures
5.1

extinguishing media
suitable extinguishing media
water spray, BC-powder, carbon dioxide (CO2)

unsuitable extinguishing media
water jet

5.2

special hazards arising from the substance or mixture

5.3

advice for firefightersin case of fire and/or explosion do not breathe fumes. co-ordinate firefighting measures to the fire surroundings. do not allow firefighting water to enter drains or water courses. collect contaminated firefighting water separately. fight fire withnormal precautions from a reasonable distance.

SECTION 6: Accidental release measures
6.1

personal precautions, protective equipment and emergency procedures
for non-emergency personnel
remove persons to safety.

for emergency responders
wear breathing apparatus if exposed to vapours/dust/spray/gases.

6.2

environmental precautions
keep away from drains, surface and ground water. retain contaminated washing water and dispose of it.

United Kingdom: en

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Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

MagBuffer B
version number: GHS 1.0

6.3

date of compilation: 2020-04-07

methods and material for containment and cleaning up
advice on how to contain a spillcovering of drains

advice on how to clean up a spill
wipe up with absorbent material (e.g. cloth, fleece). collect spillage: sawdust, kieselgur (diatomite), sand, universal binder

appropriate containment techniques
use of adsorbent materials.

other information relating to spills and releases
place in appropriate containers for disposal. ventilate affected area.

6.4

reference to other sections
personal protective equipment: see section 8. incompatible materials: see section 10. disposal considerations: see section
13.

SECTION 7: Handling and storage
7.1

precautions for safe handlingrecommendations- measures to prevent fire as well as aerosol and dust generation
use local and general ventilation. use only in well-ventilated areas.

advice on general occupational hygiene
wash hands after use. do not eat, drink and smoke in work areas. remove contaminated clothing and protective equipment
before entering eating areas. never keep food or drink in the vicinity of chemicals. never place chemicals in containers thatare normally used for food or drink. keep away from food, drink and animal feedingstuffs.

7.2

conditions for safe storage, including any incompatibilities
control of effects
protect against external exposure, such as
frost

7.3

specific end use(s)see section 16 for a general overview.

SECTION 8: Exposure controls/personal protection
8.1

control parameters
this information is not available.

8.2

exposure controls
appropriate engineering controls
general ventilation.

individual protection measures (personal protective equipment)eye/face protection
wear eye/face protection.

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Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

MagBuffer B
version number: GHS 1.0

date of compilation: 2020-04-07

skin protection- hand protection
wear suitable gloves. chemical protection gloves are suitable, which are tested according to EN 374. check leak-tightness/
impermeability prior to use. in the case of wanting to use the gloves again, clean them before taking off and air them well.
for special purposes, it is recommended to check the resistance to chemicals of the protective gloves mentioned above together with the supplier of these gloves.

- other protection measurestake recovery periods for skin regeneration. preventive skin protection (barrier creams/ointments) is recommended. wash
hands thoroughly after handling.

respiratory protection
in case of inadequate ventilation wear respiratory protection.

environmental exposure controls
use appropriate container to avoid environmental contamination. keep away from drains, surface and ground water.

SECTION 9: Physical and chemical properties
9.1

information on basic physical and chemical properties
appearancephysical stateliquidcolourcolourlessodour

odourlessother safety parameters
pH (value)

not determinedmelting point/freezing point

not determined

initial boiling point and boiling range

not determinedflash point

not determined

evaporation rate

not determined

flammability (solid, gas)

not relevant, (fluid)

explosive limits

not determinedvapour pressure

not determined

density

not determinedvapour density

this information is not available

relative density

information on this property is not available

solubility(ies)not determinedpartition coefficient- n-octanol/water (log KOW)
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MagBuffer B
version number: GHS 1.0

9.2

date of compilation: 2020-04-07

auto-ignition temperature

not determinedviscosity

not determined

explosive properties

none

oxidising properties

none

other information

there is no additional information

SECTION 10: Stability and reactivity
10.1

reactivity
concerning incompatibility: see below "Conditions to avoid" and "Incompatible materials".

10.2

chemical stability
the material is stable under normal ambient and anticipated storage and handling conditions of temperature and pressure.

10.3

possibility of hazardous reactions
no known hazardous reactions.

10.4

conditions to avoid
there are no specific conditions known which have to be avoided.

10.5

incompatible materials
there is no additional information.

10.6

hazardous decomposition products
reasonably anticipated hazardous decomposition products produced as a result of use, storage, spill and heating are notknown. hazardous combustion products: see section 5.

SECTION 11: Toxicological information
11.1

information on toxicological effects
test data are not available for the complete mixture.

classification procedurethe method for classification of the mixture is based on ingredients of the mixture (additivity formula).

classification according to GHS (1272/2008/EC, CLP)
this mixture does not meet the criteria for classification in accordance with Regulation No 1272/2008/EC.

acute toxicity
shall not be classified as acutely toxic.

skin corrosion/irritation
shall not be classified as corrosive/irritant to skin.

serious eye damage/eye irritation
shall not be classified as seriously damaging to the eye or eye irritant.

respiratory or skin sensitisation
shall not be classified as a respiratory or skin sensitiser.

germ cell mutagenicity
shall not be classified as germ cell mutagenic.

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MagBuffer B
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date of compilation: 2020-04-07

carcinogenicity
shall not be classified as carcinogenic.

reproductive toxicity
shall not be classified as a reproductive toxicant.

specific target organ toxicity - single exposure
shall not be classified as a specific target organ toxicant (single exposure).

specific target organ toxicity - repeated exposure
shall not be classified as a specific target organ toxicant (repeated exposure).

aspiration hazard
shall not be classified as presenting an aspiration hazard.

SECTION 12: Ecological information
12.1

toxicity
shall not be classified as hazardous to the aquatic environment.

12.2

persistence and degradability
data are not available.

12.3

bioaccumulative potential
data are not available.

12.4

mobility in soil
data are not available.

12.5

results of PBT and vPvB assessment
data are not available.

12.6

other adverse effects
data are not available.

SECTION 13: Disposal considerations
13.1

waste treatment methods
sewage disposal-relevant information
do not empty into drains. avoid release to the environment. Refer to special instructions/safety data sheets.

waste treatment of containers/packagingscompletely emptied packages can be recycled. handle contaminated packages in the same way as the substance itself.

remarks
please consider the relevant national or regional provisions. waste shall be separated into the categories that can behandled separately by the local or national waste management facilities.

United Kingdom: en

page: 6 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

MagBuffer B
version number: GHS 1.0

date of compilation: 2020-04-07

SECTION 14: Transport information
14.1

UN numbernot subject to transport regulations

14.2

UN proper shipping namenot relevant

14.3

transport hazard class(es)

none

14.4

packing group

not assigned to a packing group

14.5

environmental hazards

non-environmentally hazardous acc. to the dangerous goods regulations

14.6

special precautions for user
there is no additional information.

14.7

transport in bulk according to Annex II of MARPOL and the IBC Codethe cargo is not intended to be carried in bulk.

Information for each of the UN Model Regulationstransport of dangerous goods by road, rail and inland waterway (ADR/RID/ADN)
not subject to ADR, RID and ADN.

International Maritime Dangerous Goods Code (IMDG)
not subject to IMDG.

International Civil Aviation Organization (ICAO-IATA/DGR)
not subject to ICAO-IATA.

SECTION 15: Regulatory information
15.1

safety, health and environmental regulations/legislation specific for the substance or mixture

15.2

Chemical Safety Assessment
chemical safety assessments for substances in this mixture were not carried out.

SECTION 16: Other informationabbreviations and acronyms
abbr.

descriptions of used abbreviations

ADN

Accord européen relatif au transport international des marchandises dangereuses par voies de navigation
intérieures (European Agreement concerning the International Carriage of Dangerous Goods by Inland Waterways)

ADR

Accord européen relatif au transport international des marchandises dangereuses par route (European Agreement concerning the International Carriage of Dangerous Goods by Road)

CLP

Regulation (EC) No 1272/2008 on classification, labelling and packaging of substances and mixtures

DGR

Dangerous Goods Regulations (see IATA/DGR)

GHS"Globally Harmonized System of Classification and Labelling of Chemicals" developed by the United Nations

IATA

International Air Transport Association

IATA/DGR

Dangerous Goods Regulations (DGR) for the air transport (IATA)ICAOInternational Civil Aviation Organization

IMDG

International Maritime Dangerous Goods CodeUnited Kingdom: en

page: 7 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

MagBuffer B
version number: GHS 1.0

date of compilation: 2020-04-07

abbr.

descriptions of used abbreviations

MARPOLInternational Convention for the Prevention of Pollution from Ships (abbr. of "Marine Pollutant")

PBT

Persistent, Bioaccumulative and Toxic

REACH

Registration, Evaluation, Authorisation and Restriction of Chemicals

RID

Règlement concernant le transport International ferroviaire des marchandises Dangereuses (Regulations concerning the International carriage of Dangerous goods by Rail)vPvB

Very Persistent and very Bioaccumulative

key literature references and sources for data
Regulation (EC) No 1272/2008 on classification, labelling and packaging of substances and mixtures. Regulation (EC) No.
1907/2006 (REACH), amended by 2015/830/EU.
transport of dangerous goods by road, rail and inland waterway (ADR/RID/ADN). International Maritime Dangerous Goods
Code (IMDG). Dangerous Goods Regulations (DGR) for the air transport (IATA).

classification procedurephysical and chemical properties: the classification is based on tested mixture.
health hazards, environmental hazards: the method for classification of the mixture is based on ingredients of the mixture(additivity formula).

disclaimer
this information is based upon the present state of our knowledge. this SDS has been compiled and is solely intended for thisproduct.

United Kingdom: en

page: 8 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

MagBuffer C
version number: GHS 1.0

date of compilation: 2020-04-07

SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1

1.2

product identifiertrade name

MagBuffer C

registration number (REACH)

not relevant (mixture)

relevant identified uses of the substance or mixture and uses advised against
relevant identified uses

1.3

for research use only, not for use in diagnostic ortherapeutic procedures.

details of the supplier of the safety data sheet
Diagenode SA
LIEGE SCIENCE PARK Rue du Bois Saint-Jean, 34102 Seraing
Belgium
telephone: +32 4 364 20 50
e-mail: info@diagenode.com

1.4

emergency telephone number
emergency information service+32 4 364 20 50
this number is only available during the following office hours: Mon-Fri 09:00 AM - 05:00 PM

poison centre
country

nametelephone

United Kingdom

National Poisons Information Service

111

SECTION 2: Hazards identification
2.1

classification of the substance or mixture
classification according to Regulation (EC) No 1272/2008 (CLP)
this mixture does not meet the criteria for classification in accordance with Regulation No 1272/2008/EC.

2.2

label elements
labelling according to Regulation (EC) No 1272/2008 (CLP)
not required

2.3

other hazards
results of PBT and vPvB assessment
this mixture does not contain any substances that are assessed to be a PBT or a vPvB.

SECTION 3: Composition/information on ingredients
3.1

substances
not relevant (mixture)

3.2

mixturesdescription of the mixtureThis mixture does not contain any potentially hazardous products.

United Kingdom: en

page: 1 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

MagBuffer C
version number: GHS 1.0

date of compilation: 2020-04-07

SECTION 4: First aid measures4.1

description of first aid measuresgeneral notes
do not leave affected person unattended. remove victim out of the danger area. keep affected person warm, still andcovered. take off immediately all contaminated clothing. in all cases of doubt, or when symptoms persist, seek medical advice. in case of unconsciousness place person in the recovery position. Never give anything by mouth.

following inhalation
if breathing is irregular or stopped, immediately seek medical assistance and start first aid actions. provide fresh air.

following skin contact
wash with plenty of soap and water.

following eye contact
remove contact lenses, if present and easy to do. Continue rinsing. irrigate copiously with clean, fresh water for at least 10
minutes, holding the eyelids apart.

following ingestionrinse mouth with water (only if the person is conscious). do NOT induce vomiting.

4.2

most important symptoms and effects, both acute and delayed
symptoms and effects are not known to date.

4.3

indication of any immediate medical attention and special treatment needed
none

SECTION 5: Firefighting measures
5.1

extinguishing media
suitable extinguishing media
water spray, BC-powder, carbon dioxide (CO2)

unsuitable extinguishing media
water jet

5.2

special hazards arising from the substance or mixture
hazardous combustion products
carbon monoxide (CO), carbon dioxide (CO2)

5.3

advice for firefightersin case of fire and/or explosion do not breathe fumes. co-ordinate firefighting measures to the fire surroundings. do not allow firefighting water to enter drains or water courses. collect contaminated firefighting water separately. fight fire withnormal precautions from a reasonable distance.

SECTION 6: Accidental release measures
6.1

personal precautions, protective equipment and emergency procedures
for non-emergency personnel
remove persons to safety.

for emergency responders
wear breathing apparatus if exposed to vapours/dust/spray/gases.

6.2

environmental precautions
keep away from drains, surface and ground water. retain contaminated washing water and dispose of it.

United Kingdom: en

page: 2 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

MagBuffer C
version number: GHS 1.0

6.3

date of compilation: 2020-04-07

methods and material for containment and cleaning up
advice on how to contain a spillcovering of drains

advice on how to clean up a spill
wipe up with absorbent material (e.g. cloth, fleece). collect spillage: sawdust, kieselgur (diatomite), sand, universal binder

appropriate containment techniques
use of adsorbent materials.

other information relating to spills and releases
place in appropriate containers for disposal. ventilate affected area.

6.4

reference to other sections
hazardous combustion products: see section 5. personal protective equipment: see section 8. incompatible materials: seesection 10. disposal considerations: see section 13.

SECTION 7: Handling and storage
7.1

precautions for safe handlingrecommendations- measures to prevent fire as well as aerosol and dust generation
use local and general ventilation. use only in well-ventilated areas.

advice on general occupational hygiene
wash hands after use. do not eat, drink and smoke in work areas. remove contaminated clothing and protective equipment
before entering eating areas. never keep food or drink in the vicinity of chemicals. never place chemicals in containers thatare normally used for food or drink. keep away from food, drink and animal feedingstuffs.

7.2

conditions for safe storage, including any incompatibilities
control of effects
protect against external exposure, such as
frost

7.3

specific end use(s)see section 16 for a general overview.

SECTION 8: Exposure controls/personal protection
8.1

control parameters
this information is not available.

8.2

exposure controls
appropriate engineering controls
general ventilation.

individual protection measures (personal protective equipment)eye/face protection
wear eye/face protection.

United Kingdom: en

page: 3 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

MagBuffer C
version number: GHS 1.0

date of compilation: 2020-04-07

skin protection- hand protection
wear suitable gloves. chemical protection gloves are suitable, which are tested according to EN 374. check leak-tightness/
impermeability prior to use. in the case of wanting to use the gloves again, clean them before taking off and air them well.
for special purposes, it is recommended to check the resistance to chemicals of the protective gloves mentioned above together with the supplier of these gloves.

- other protection measurestake recovery periods for skin regeneration. preventive skin protection (barrier creams/ointments) is recommended. wash
hands thoroughly after handling.

respiratory protection
in case of inadequate ventilation wear respiratory protection.

environmental exposure controls
use appropriate container to avoid environmental contamination. keep away from drains, surface and ground water.

SECTION 9: Physical and chemical properties
9.1

information on basic physical and chemical properties
appearancephysical stateliquidcolourlight yellow

odour

odourlessother safety parameters
pH (value)

not determinedmelting point/freezing point

not determined

initial boiling point and boiling range

not determinedflash point

not determined

evaporation rate

not determined

flammability (solid, gas)

not relevant, (fluid)

explosive limits

not determinedvapour pressure

not determined

density

not determinedvapour density

this information is not available

relative density

information on this property is not available

solubility(ies)not determinedpartition coefficient- n-octanol/water (log KOW)
United Kingdom: enthis information is not available
page: 4 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

MagBuffer C
version number: GHS 1.0

9.2

date of compilation: 2020-04-07

auto-ignition temperature

not determinedviscosity

not determined

explosive properties

none

oxidising properties

none

other information

there is no additional information

SECTION 10: Stability and reactivity
10.1

reactivity
concerning incompatibility: see below "Conditions to avoid" and "Incompatible materials".

10.2

chemical stability
the material is stable under normal ambient and anticipated storage and handling conditions of temperature and pressure.

10.3

possibility of hazardous reactions
no known hazardous reactions.

10.4

conditions to avoid
there are no specific conditions known which have to be avoided.

10.5

incompatible materials
oxidisers

10.6

hazardous decomposition products
reasonably anticipated hazardous decomposition products produced as a result of use, storage, spill and heating are notknown. hazardous combustion products: see section 5.

SECTION 11: Toxicological information
11.1

information on toxicological effects
test data are not available for the complete mixture.

classification procedurethe method for classification of the mixture is based on ingredients of the mixture (additivity formula).

classification according to GHS (1272/2008/EC, CLP)
this mixture does not meet the criteria for classification in accordance with Regulation No 1272/2008/EC.

acute toxicity
shall not be classified as acutely toxic.

skin corrosion/irritation
shall not be classified as corrosive/irritant to skin.

serious eye damage/eye irritation
shall not be classified as seriously damaging to the eye or eye irritant.

respiratory or skin sensitisation
shall not be classified as a respiratory or skin sensitiser.

germ cell mutagenicity
shall not be classified as germ cell mutagenic.

United Kingdom: en

page: 5 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

MagBuffer C
version number: GHS 1.0

date of compilation: 2020-04-07

carcinogenicity
shall not be classified as carcinogenic.

reproductive toxicity
shall not be classified as a reproductive toxicant.

specific target organ toxicity - single exposure
shall not be classified as a specific target organ toxicant (single exposure).

specific target organ toxicity - repeated exposure
shall not be classified as a specific target organ toxicant (repeated exposure).

aspiration hazard
shall not be classified as presenting an aspiration hazard.

SECTION 12: Ecological information
12.1

toxicity
shall not be classified as hazardous to the aquatic environment.

12.2

persistence and degradability
data are not available.

12.3

bioaccumulative potential
data are not available.

12.4

mobility in soil
data are not available.

12.5

results of PBT and vPvB assessment
data are not available.

12.6

other adverse effects
data are not available.

SECTION 13: Disposal considerations
13.1

waste treatment methods
sewage disposal-relevant information
do not empty into drains. avoid release to the environment. Refer to special instructions/safety data sheets.

waste treatment of containers/packagingscompletely emptied packages can be recycled. handle contaminated packages in the same way as the substance itself.

remarks
please consider the relevant national or regional provisions. waste shall be separated into the categories that can behandled separately by the local or national waste management facilities.

United Kingdom: en

page: 6 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

MagBuffer C
version number: GHS 1.0

date of compilation: 2020-04-07

SECTION 14: Transport information
14.1

UN numbernot subject to transport regulations

14.2

UN proper shipping namenot relevant

14.3

transport hazard class(es)

none

14.4

packing group

not assigned to a packing group

14.5

environmental hazards

non-environmentally hazardous acc. to the dangerous goods regulations

14.6

special precautions for user
there is no additional information.

14.7

transport in bulk according to Annex II of MARPOL and the IBC Codethe cargo is not intended to be carried in bulk.

Information for each of the UN Model Regulationstransport of dangerous goods by road, rail and inland waterway (ADR/RID/ADN)
not subject to ADR, RID and ADN.

International Maritime Dangerous Goods Code (IMDG)
not subject to IMDG.

International Civil Aviation Organization (ICAO-IATA/DGR)
not subject to ICAO-IATA.

SECTION 15: Regulatory information
15.1

safety, health and environmental regulations/legislation specific for the substance or mixture

15.2

Chemical Safety Assessment
chemical safety assessments for substances in this mixture were not carried out.

SECTION 16: Other informationabbreviations and acronyms
abbr.

descriptions of used abbreviations

ADN

Accord européen relatif au transport international des marchandises dangereuses par voies de navigation
intérieures (European Agreement concerning the International Carriage of Dangerous Goods by Inland Waterways)

ADR

Accord européen relatif au transport international des marchandises dangereuses par route (European Agreement concerning the International Carriage of Dangerous Goods by Road)

CLP

Regulation (EC) No 1272/2008 on classification, labelling and packaging of substances and mixtures

DGR

Dangerous Goods Regulations (see IATA/DGR)

GHS"Globally Harmonized System of Classification and Labelling of Chemicals" developed by the United Nations

IATA

International Air Transport Association

IATA/DGR

Dangerous Goods Regulations (DGR) for the air transport (IATA)ICAOInternational Civil Aviation Organization

IMDG

International Maritime Dangerous Goods CodeUnited Kingdom: en

page: 7 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

MagBuffer C
version number: GHS 1.0

date of compilation: 2020-04-07

abbr.

descriptions of used abbreviations

MARPOLInternational Convention for the Prevention of Pollution from Ships (abbr. of "Marine Pollutant")

PBT

Persistent, Bioaccumulative and Toxic

REACH

Registration, Evaluation, Authorisation and Restriction of Chemicals

RID

Règlement concernant le transport International ferroviaire des marchandises Dangereuses (Regulations concerning the International carriage of Dangerous goods by Rail)vPvB

Very Persistent and very Bioaccumulative

key literature references and sources for data
Regulation (EC) No 1272/2008 on classification, labelling and packaging of substances and mixtures. Regulation (EC) No.
1907/2006 (REACH), amended by 2015/830/EU.
transport of dangerous goods by road, rail and inland waterway (ADR/RID/ADN). International Maritime Dangerous Goods
Code (IMDG). Dangerous Goods Regulations (DGR) for the air transport (IATA).

classification procedurephysical and chemical properties: the classification is based on tested mixture.
health hazards, environmental hazards: the method for classification of the mixture is based on ingredients of the mixture(additivity formula).

disclaimer
this information is based upon the present state of our knowledge. this SDS has been compiled and is solely intended for thisproduct.

United Kingdom: en

page: 8 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

5-mC monoclonal antibody 33D3
version number: GHS 1.0

date of compilation: 2020-01-30

SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1

1.2

product identifiertrade name5-mC monoclonal antibody 33D3

registration number (REACH)

not relevant (mixture)

product code(s)C15200081

relevant identified uses of the substance or mixture and uses advised against
relevant identified uses

1.3

for research use only, not for use in diagnostic ortherapeutic procedures.

details of the supplier of the safety data sheet
Diagenode SA
LIEGE SCIENCE PARK Rue du Bois Saint-Jean, 34102 Seraing
Belgium
telephone: +32 4 364 20 50
e-mail: info@diagenode.com

1.4

emergency telephone number
emergency information service+32 4 364 20 50
this number is only available during the following office hours: Mon-Fri 09:00 AM - 05:00 PM

poison centre
country

nametelephone

United Kingdom

National Poisons Information Service

111

SECTION 2: Hazards identification
2.1

classification of the substance or mixture
classification according to Regulation (EC) No 1272/2008 (CLP)
this mixture does not meet the criteria for classification in accordance with Regulation No 1272/2008/EC.

2.2

label elements
labelling according to Regulation (EC) No 1272/2008 (CLP)
not required

2.3

other hazards
results of PBT and vPvB assessment
this mixture does not contain any substances that are assessed to be a PBT or a vPvB.

United Kingdom: en

page: 1 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

5-mC monoclonal antibody 33D3
version number: GHS 1.0

date of compilation: 2020-01-30

SECTION 3: Composition/information on ingredients
3.1

substances
not relevant (mixture)

3.2

mixturesdescription of the mixtureThis product is composed of antibodies in aqueous buffer solution. It contains 0.05% sodium azide as preservative.

SECTION 4: First aid measures4.1

description of first aid measuresgeneral notes
do not leave affected person unattended. remove victim out of the danger area. keep affected person warm, still andcovered. take off immediately all contaminated clothing. in all cases of doubt, or when symptoms persist, seek medical advice. in case of unconsciousness place person in the recovery position. Never give anything by mouth.

following inhalation
if breathing is irregular or stopped, immediately seek medical assistance and start first aid actions. provide fresh air.

following skin contact
wash with plenty of soap and water.

following eye contact
remove contact lenses, if present and easy to do. Continue rinsing. irrigate copiously with clean, fresh water for at least 10
minutes, holding the eyelids apart.

following ingestionrinse mouth with water (only if the person is conscious). do NOT induce vomiting.

4.2

most important symptoms and effects, both acute and delayed
symptoms and effects are not known to date.

4.3

indication of any immediate medical attention and special treatment needed
none

SECTION 5: Firefighting measures
5.1

extinguishing media
suitable extinguishing media
water spray, BC-powder, carbon dioxide (CO2)

unsuitable extinguishing media
water jet

5.2

special hazards arising from the substance or mixture
hazardous combustion products
nitrogen oxides (NOx)

5.3

advice for firefightersin case of fire and/or explosion do not breathe fumes. co-ordinate firefighting measures to the fire surroundings. do not allow firefighting water to enter drains or water courses. collect contaminated firefighting water separately. fight fire withnormal precautions from a reasonable distance.

United Kingdom: en

page: 2 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

5-mC monoclonal antibody 33D3
version number: GHS 1.0

date of compilation: 2020-01-30

SECTION 6: Accidental release measures
6.1

personal precautions, protective equipment and emergency procedures
for non-emergency personnel
remove persons to safety.

for emergency responders
wear breathing apparatus if exposed to vapours/dust/spray/gases.

6.2

environmental precautions
keep away from drains, surface and ground water. retain contaminated washing water and dispose of it.

6.3

methods and material for containment and cleaning up
advice on how to contain a spillcovering of drains

advice on how to clean up a spill
wipe up with absorbent material (e.g. cloth, fleece). collect spillage: sawdust, kieselgur (diatomite), sand, universal binder

appropriate containment techniques
use of adsorbent materials.

other information relating to spills and releases
place in appropriate containers for disposal. ventilate affected area.

6.4

reference to other sections
hazardous combustion products: see section 5. personal protective equipment: see section 8. incompatible materials: seesection 10. disposal considerations: see section 13.

SECTION 7: Handling and storage
7.1

precautions for safe handlingrecommendations- measures to prevent fire as well as aerosol and dust generation
use local and general ventilation. use only in well-ventilated areas.

advice on general occupational hygiene
wash hands after use. do not eat, drink and smoke in work areas. remove contaminated clothing and protective equipment
before entering eating areas. never keep food or drink in the vicinity of chemicals. never place chemicals in containers thatare normally used for food or drink. keep away from food, drink and animal feedingstuffs.

7.2

conditions for safe storage, including any incompatibilities
control of effects
protect against external exposure, such as
frost

7.3

specific end use(s)see section 16 for a general overview.

United Kingdom: en

page: 3 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

5-mC monoclonal antibody 33D3
version number: GHS 1.0

date of compilation: 2020-01-30

SECTION 8: Exposure controls/personal protection
8.1

control parameters
this information is not available.

8.2

exposure controls
appropriate engineering controls
general ventilation.

individual protection measures (personal protective equipment)eye/face protection
wear eye/face protection.

skin protection- hand protection
wear suitable gloves. chemical protection gloves are suitable, which are tested according to EN 374. check leak-tightness/
impermeability prior to use. in the case of wanting to use the gloves again, clean them before taking off and air them well.
for special purposes, it is recommended to check the resistance to chemicals of the protective gloves mentioned above together with the supplier of these gloves.

- other protection measurestake recovery periods for skin regeneration. preventive skin protection (barrier creams/ointments) is recommended. wash
hands thoroughly after handling.

respiratory protection
in case of inadequate ventilation wear respiratory protection.

environmental exposure controls
use appropriate container to avoid environmental contamination. keep away from drains, surface and ground water.

SECTION 9: Physical and chemical properties
9.1

information on basic physical and chemical properties
appearancephysical stateliquidcolourcolourlessodour

odourlessother safety parameters
pH (value)

not determinedmelting point/freezing point

not determined

initial boiling point and boiling range

not determinedflash point

not determined

evaporation rate

not determined

flammability (solid, gas)

not relevant, (fluid)

explosive limits

not determined

United Kingdom: en

page: 4 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

5-mC monoclonal antibody 33D3
version number: GHS 1.0

date of compilation: 2020-01-30

vapour pressure

not determined

density

not determinedvapour density

this information is not available

relative density

information on this property is not available

solubility(ies)not determinedpartition coefficient9.2- n-octanol/water (log KOW)

this information is not available

auto-ignition temperature

not determinedviscosity

not determined

explosive properties

none

oxidising properties

none

other information

there is no additional information

SECTION 10: Stability and reactivity
10.1

reactivity
concerning incompatibility: see below "Conditions to avoid" and "Incompatible materials".

10.2

chemical stability
the material is stable under normal ambient and anticipated storage and handling conditions of temperature and pressure.

10.3

possibility of hazardous reactions
no known hazardous reactions.

10.4

conditions to avoid
there are no specific conditions known which have to be avoided.

10.5

incompatible materials
there is no additional information.

10.6

hazardous decomposition products
reasonably anticipated hazardous decomposition products produced as a result of use, storage, spill and heating are notknown. hazardous combustion products: see section 5.

SECTION 11: Toxicological information
11.1

information on toxicological effects
test data are not available for the complete mixture.

classification procedurethe method for classification of the mixture is based on ingredients of the mixture (additivity formula).

classification according to GHS (1272/2008/EC, CLP)
this mixture does not meet the criteria for classification in accordance with Regulation No 1272/2008/EC.

United Kingdom: en

page: 5 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

5-mC monoclonal antibody 33D3
version number: GHS 1.0

date of compilation: 2020-01-30

acute toxicity
shall not be classified as acutely toxic.

skin corrosion/irritation
shall not be classified as corrosive/irritant to skin.

serious eye damage/eye irritation
shall not be classified as seriously damaging to the eye or eye irritant.

respiratory or skin sensitisation
shall not be classified as a respiratory or skin sensitiser.

germ cell mutagenicity
shall not be classified as germ cell mutagenic.

carcinogenicity
shall not be classified as carcinogenic.

reproductive toxicity
shall not be classified as a reproductive toxicant.

specific target organ toxicity - single exposure
shall not be classified as a specific target organ toxicant (single exposure).

specific target organ toxicity - repeated exposure
shall not be classified as a specific target organ toxicant (repeated exposure).

aspiration hazard
shall not be classified as presenting an aspiration hazard.

SECTION 12: Ecological information
12.1

toxicity
shall not be classified as hazardous to the aquatic environment.

12.2

persistence and degradability
data are not available.

12.3

bioaccumulative potential
data are not available.

12.4

mobility in soil
data are not available.

12.5

results of PBT and vPvB assessment
data are not available.

12.6

other adverse effects
data are not available.

United Kingdom: en

page: 6 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

5-mC monoclonal antibody 33D3
version number: GHS 1.0

date of compilation: 2020-01-30

SECTION 13: Disposal considerations
13.1

waste treatment methods
sewage disposal-relevant information
do not empty into drains. avoid release to the environment. Refer to special instructions/safety data sheets.

waste treatment of containers/packagingscompletely emptied packages can be recycled. handle contaminated packages in the same way as the substance itself.

remarks
please consider the relevant national or regional provisions. waste shall be separated into the categories that can behandled separately by the local or national waste management facilities.

SECTION 14: Transport information
14.1

UN numbernot subject to transport regulations

14.2

UN proper shipping namenot relevant

14.3

transport hazard class(es)

none

14.4

packing group

not assigned to a packing group

14.5

environmental hazards

non-environmentally hazardous acc. to the dangerous goods regulations

14.6

special precautions for user
there is no additional information.

14.7

transport in bulk according to Annex II of MARPOL and the IBC Codethe cargo is not intended to be carried in bulk.

Information for each of the UN Model Regulationstransport of dangerous goods by road, rail and inland waterway (ADR/RID/ADN)
not subject to ADR, RID and ADN.

International Maritime Dangerous Goods Code (IMDG)
not subject to IMDG.

International Civil Aviation Organization (ICAO-IATA/DGR)
not subject to ICAO-IATA.

SECTION 15: Regulatory information
15.1

safety, health and environmental regulations/legislation specific for the substance or mixture

15.2

Chemical Safety Assessment
chemical safety assessments for substances in this mixture were not carried out.

United Kingdom: en

page: 7 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

5-mC monoclonal antibody 33D3
version number: GHS 1.0

date of compilation: 2020-01-30

SECTION 16: Other informationabbreviations and acronyms
abbr.

descriptions of used abbreviations

ADN

Accord européen relatif au transport international des marchandises dangereuses par voies de navigation
intérieures (European Agreement concerning the International Carriage of Dangerous Goods by Inland Waterways)

ADR

Accord européen relatif au transport international des marchandises dangereuses par route (European Agreement concerning the International Carriage of Dangerous Goods by Road)

CLP

Regulation (EC) No 1272/2008 on classification, labelling and packaging of substances and mixtures

DGR

Dangerous Goods Regulations (see IATA/DGR)

GHS"Globally Harmonized System of Classification and Labelling of Chemicals" developed by the United Nations

IATA

International Air Transport Association

IATA/DGR

Dangerous Goods Regulations (DGR) for the air transport (IATA)ICAOInternational Civil Aviation Organization

IMDG

International Maritime Dangerous Goods CodeMARPOLInternational Convention for the Prevention of Pollution from Ships (abbr. of "Marine Pollutant")

PBT

Persistent, Bioaccumulative and Toxic

REACH

Registration, Evaluation, Authorisation and Restriction of Chemicals

RID

Règlement concernant le transport International ferroviaire des marchandises Dangereuses (Regulations concerning the International carriage of Dangerous goods by Rail)vPvB

Very Persistent and very Bioaccumulative

key literature references and sources for data
Regulation (EC) No 1272/2008 on classification, labelling and packaging of substances and mixtures. Regulation (EC) No.
1907/2006 (REACH), amended by 2015/830/EU.
transport of dangerous goods by road, rail and inland waterway (ADR/RID/ADN). International Maritime Dangerous Goods
Code (IMDG). Dangerous Goods Regulations (DGR) for the air transport (IATA).

classification procedurephysical and chemical properties: the classification is based on tested mixture.
health hazards, environmental hazards: the method for classification of the mixture is based on ingredients of the mixture(additivity formula).

disclaimer
this information is based upon the present state of our knowledge. this SDS has been compiled and is solely intended for thisproduct.

United Kingdom: en

page: 8 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

Methylated spike-in control
version number: GHS 1.0

date of compilation: 2020-04-07

SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1

1.2

product identifiertrade nameMethylated spike-in control

registration number (REACH)

not relevant (mixture)

relevant identified uses of the substance or mixture and uses advised against
relevant identified uses

1.3

for research use only, not for use in diagnostic ortherapeutic procedures.

details of the supplier of the safety data sheet
Diagenode SA
LIEGE SCIENCE PARK Rue du Bois Saint-Jean, 34102 Seraing
Belgium
telephone: +32 4 364 20 50
e-mail: info@diagenode.com

1.4

emergency telephone number
emergency information service+32 4 364 20 50
this number is only available during the following office hours: Mon-Fri 09:00 AM - 05:00 PM

poison centre
country

nametelephone

United Kingdom

National Poisons Information Service

111

SECTION 2: Hazards identification
2.1

classification of the substance or mixture
classification according to Regulation (EC) No 1272/2008 (CLP)
this mixture does not meet the criteria for classification in accordance with Regulation No 1272/2008/EC.

2.2

label elements
labelling according to Regulation (EC) No 1272/2008 (CLP)
not required

2.3

other hazards
results of PBT and vPvB assessment
this mixture does not contain any substances that are assessed to be a PBT or a vPvB.

SECTION 3: Composition/information on ingredients
3.1

substances
not relevant (mixture)

3.2

mixturesdescription of the mixtureThis mixture does not contain any potentially hazardous products.

United Kingdom: en

page: 1 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

Methylated spike-in control
version number: GHS 1.0

date of compilation: 2020-04-07

SECTION 4: First aid measures4.1

description of first aid measuresgeneral notes
do not leave affected person unattended. remove victim out of the danger area. keep affected person warm, still andcovered. take off immediately all contaminated clothing. in all cases of doubt, or when symptoms persist, seek medical advice. in case of unconsciousness place person in the recovery position. Never give anything by mouth.

following inhalation
if breathing is irregular or stopped, immediately seek medical assistance and start first aid actions. provide fresh air.

following skin contact
wash with plenty of soap and water.

following eye contact
remove contact lenses, if present and easy to do. Continue rinsing. irrigate copiously with clean, fresh water for at least 10
minutes, holding the eyelids apart.

following ingestionrinse mouth with water (only if the person is conscious). do NOT induce vomiting.

4.2

most important symptoms and effects, both acute and delayed
symptoms and effects are not known to date.

4.3

indication of any immediate medical attention and special treatment needed
none

SECTION 5: Firefighting measures
5.1

extinguishing media
suitable extinguishing media
water spray, BC-powder, carbon dioxide (CO2)

unsuitable extinguishing media
water jet

5.2

special hazards arising from the substance or mixture
hazardous combustion products
nitrogen oxides (NOx)

5.3

advice for firefightersin case of fire and/or explosion do not breathe fumes. co-ordinate firefighting measures to the fire surroundings. do not allow firefighting water to enter drains or water courses. collect contaminated firefighting water separately. fight fire withnormal precautions from a reasonable distance.

SECTION 6: Accidental release measures
6.1

personal precautions, protective equipment and emergency procedures
for non-emergency personnel
remove persons to safety.

for emergency responders
wear breathing apparatus if exposed to vapours/dust/spray/gases.

6.2

environmental precautions
keep away from drains, surface and ground water. retain contaminated washing water and dispose of it.

United Kingdom: en

page: 2 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

Methylated spike-in control
version number: GHS 1.0

6.3

date of compilation: 2020-04-07

methods and material for containment and cleaning up
advice on how to contain a spillcovering of drains

advice on how to clean up a spill
wipe up with absorbent material (e.g. cloth, fleece). collect spillage: sawdust, kieselgur (diatomite), sand, universal binder

appropriate containment techniques
use of adsorbent materials.

other information relating to spills and releases
place in appropriate containers for disposal. ventilate affected area.

6.4

reference to other sections
hazardous combustion products: see section 5. personal protective equipment: see section 8. incompatible materials: seesection 10. disposal considerations: see section 13.

SECTION 7: Handling and storage
7.1

precautions for safe handlingrecommendations- measures to prevent fire as well as aerosol and dust generation
use local and general ventilation. use only in well-ventilated areas.

advice on general occupational hygiene
wash hands after use. do not eat, drink and smoke in work areas. remove contaminated clothing and protective equipment
before entering eating areas. never keep food or drink in the vicinity of chemicals. never place chemicals in containers thatare normally used for food or drink. keep away from food, drink and animal feedingstuffs.

7.2

conditions for safe storage, including any incompatibilities
control of effects
protect against external exposure, such as
frost

7.3

specific end use(s)see section 16 for a general overview.

SECTION 8: Exposure controls/personal protection
8.1

control parameters
this information is not available.

8.2

exposure controls
appropriate engineering controls
general ventilation.

individual protection measures (personal protective equipment)eye/face protection
wear eye/face protection.

United Kingdom: en

page: 3 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

Methylated spike-in control
version number: GHS 1.0

date of compilation: 2020-04-07

skin protection- hand protection
wear suitable gloves. chemical protection gloves are suitable, which are tested according to EN 374. check leak-tightness/
impermeability prior to use. in the case of wanting to use the gloves again, clean them before taking off and air them well.
for special purposes, it is recommended to check the resistance to chemicals of the protective gloves mentioned above together with the supplier of these gloves.

- other protection measurestake recovery periods for skin regeneration. preventive skin protection (barrier creams/ointments) is recommended. wash
hands thoroughly after handling.

respiratory protection
in case of inadequate ventilation wear respiratory protection.

environmental exposure controls
use appropriate container to avoid environmental contamination. keep away from drains, surface and ground water.

SECTION 9: Physical and chemical properties
9.1

information on basic physical and chemical properties
appearancephysical stateliquidcolourcolourlessodour

odourlessother safety parameters
pH (value)

not determinedmelting point/freezing point

not determined

initial boiling point and boiling range

not determinedflash point

not determined

evaporation rate

not determined

flammability (solid, gas)

not relevant, (fluid)

explosive limits

not determinedvapour pressure

not determined

density

not determinedvapour density

this information is not available

relative density

information on this property is not available

solubility(ies)not determinedpartition coefficient- n-octanol/water (log KOW)
United Kingdom: enthis information is not available
page: 4 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

Methylated spike-in control
version number: GHS 1.0

9.2

date of compilation: 2020-04-07

auto-ignition temperature

not determinedviscosity

not determined

explosive properties

none

oxidising properties

none

other information

there is no additional information

SECTION 10: Stability and reactivity
10.1

reactivity
concerning incompatibility: see below "Conditions to avoid" and "Incompatible materials".

10.2

chemical stability
the material is stable under normal ambient and anticipated storage and handling conditions of temperature and pressure.

10.3

possibility of hazardous reactions
no known hazardous reactions.

10.4

conditions to avoid
there are no specific conditions known which have to be avoided.

10.5

incompatible materials
there is no additional information.

10.6

hazardous decomposition products
reasonably anticipated hazardous decomposition products produced as a result of use, storage, spill and heating are notknown. hazardous combustion products: see section 5.

SECTION 11: Toxicological information
11.1

information on toxicological effects
test data are not available for the complete mixture.

classification procedurethe method for classification of the mixture is based on ingredients of the mixture (additivity formula).

classification according to GHS (1272/2008/EC, CLP)
this mixture does not meet the criteria for classification in accordance with Regulation No 1272/2008/EC.

acute toxicity
shall not be classified as acutely toxic.

skin corrosion/irritation
shall not be classified as corrosive/irritant to skin.

serious eye damage/eye irritation
shall not be classified as seriously damaging to the eye or eye irritant.

respiratory or skin sensitisation
shall not be classified as a respiratory or skin sensitiser.

germ cell mutagenicity
shall not be classified as germ cell mutagenic.

United Kingdom: en

page: 5 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

Methylated spike-in control
version number: GHS 1.0

date of compilation: 2020-04-07

carcinogenicity
shall not be classified as carcinogenic.

reproductive toxicity
shall not be classified as a reproductive toxicant.

specific target organ toxicity - single exposure
shall not be classified as a specific target organ toxicant (single exposure).

specific target organ toxicity - repeated exposure
shall not be classified as a specific target organ toxicant (repeated exposure).

aspiration hazard
shall not be classified as presenting an aspiration hazard.

SECTION 12: Ecological information
12.1

toxicity
shall not be classified as hazardous to the aquatic environment.

12.2

persistence and degradability
data are not available.

12.3

bioaccumulative potential
data are not available.

12.4

mobility in soil
data are not available.

12.5

results of PBT and vPvB assessment
data are not available.

12.6

other adverse effects
data are not available.

SECTION 13: Disposal considerations
13.1

waste treatment methods
sewage disposal-relevant information
do not empty into drains. avoid release to the environment. Refer to special instructions/safety data sheets.

waste treatment of containers/packagingscompletely emptied packages can be recycled. handle contaminated packages in the same way as the substance itself.

remarks
please consider the relevant national or regional provisions. waste shall be separated into the categories that can behandled separately by the local or national waste management facilities.

United Kingdom: en

page: 6 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

Methylated spike-in control
version number: GHS 1.0

date of compilation: 2020-04-07

SECTION 14: Transport information
14.1

UN numbernot subject to transport regulations

14.2

UN proper shipping namenot relevant

14.3

transport hazard class(es)

none

14.4

packing group

not assigned to a packing group

14.5

environmental hazards

non-environmentally hazardous acc. to the dangerous goods regulations

14.6

special precautions for user
there is no additional information.

14.7

transport in bulk according to Annex II of MARPOL and the IBC Codethe cargo is not intended to be carried in bulk.

Information for each of the UN Model Regulationstransport of dangerous goods by road, rail and inland waterway (ADR/RID/ADN)
not subject to ADR, RID and ADN.

International Maritime Dangerous Goods Code (IMDG)
not subject to IMDG.

International Civil Aviation Organization (ICAO-IATA/DGR)
not subject to ICAO-IATA.

SECTION 15: Regulatory information
15.1

safety, health and environmental regulations/legislation specific for the substance or mixture

15.2

Chemical Safety Assessment
chemical safety assessments for substances in this mixture were not carried out.

SECTION 16: Other informationabbreviations and acronyms
abbr.

descriptions of used abbreviations

ADN

Accord européen relatif au transport international des marchandises dangereuses par voies de navigation
intérieures (European Agreement concerning the International Carriage of Dangerous Goods by Inland Waterways)

ADR

Accord européen relatif au transport international des marchandises dangereuses par route (European Agreement concerning the International Carriage of Dangerous Goods by Road)

CLP

Regulation (EC) No 1272/2008 on classification, labelling and packaging of substances and mixtures

DGR

Dangerous Goods Regulations (see IATA/DGR)

GHS"Globally Harmonized System of Classification and Labelling of Chemicals" developed by the United Nations

IATA

International Air Transport Association

IATA/DGR

Dangerous Goods Regulations (DGR) for the air transport (IATA)ICAOInternational Civil Aviation Organization

IMDG

International Maritime Dangerous Goods CodeUnited Kingdom: en

page: 7 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

Methylated spike-in control
version number: GHS 1.0

date of compilation: 2020-04-07

abbr.

descriptions of used abbreviations

MARPOLInternational Convention for the Prevention of Pollution from Ships (abbr. of "Marine Pollutant")

PBT

Persistent, Bioaccumulative and Toxic

REACH

Registration, Evaluation, Authorisation and Restriction of Chemicals

RID

Règlement concernant le transport International ferroviaire des marchandises Dangereuses (Regulations concerning the International carriage of Dangerous goods by Rail)vPvB

Very Persistent and very Bioaccumulative

key literature references and sources for data
Regulation (EC) No 1272/2008 on classification, labelling and packaging of substances and mixtures. Regulation (EC) No.
1907/2006 (REACH), amended by 2015/830/EU.
transport of dangerous goods by road, rail and inland waterway (ADR/RID/ADN). International Maritime Dangerous Goods
Code (IMDG). Dangerous Goods Regulations (DGR) for the air transport (IATA).

classification procedurephysical and chemical properties: the classification is based on tested mixture.
health hazards, environmental hazards: the method for classification of the mixture is based on ingredients of the mixture(additivity formula).

disclaimer
this information is based upon the present state of our knowledge. this SDS has been compiled and is solely intended for thisproduct.

United Kingdom: en

page: 8 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

Unmethylated spike-in control
version number: GHS 1.0

date of compilation: 2020-04-07

SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1

1.2

product identifiertrade name

Unmethylated spike-in control

registration number (REACH)

not relevant (mixture)

relevant identified uses of the substance or mixture and uses advised against
relevant identified uses

1.3

for research use only, not for use in diagnostic ortherapeutic procedures.

details of the supplier of the safety data sheet
Diagenode SA
LIEGE SCIENCE PARK Rue du Bois Saint-Jean, 34102 Seraing
Belgium
telephone: +32 4 364 20 50
e-mail: info@diagenode.com

1.4

emergency telephone number
emergency information service+32 4 364 20 50
this number is only available during the following office hours: Mon-Fri 09:00 AM - 05:00 PM

poison centre
country

nametelephone

United Kingdom

National Poisons Information Service

111

SECTION 2: Hazards identification
2.1

classification of the substance or mixture
classification according to Regulation (EC) No 1272/2008 (CLP)
this mixture does not meet the criteria for classification in accordance with Regulation No 1272/2008/EC.

2.2

label elements
labelling according to Regulation (EC) No 1272/2008 (CLP)
not required

2.3

other hazards
results of PBT and vPvB assessment
this mixture does not contain any substances that are assessed to be a PBT or a vPvB.

SECTION 3: Composition/information on ingredients
3.1

substances
not relevant (mixture)

3.2

mixturesdescription of the mixtureThis mixture does not contain any potentially hazardous products.

United Kingdom: en

page: 1 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

Unmethylated spike-in control
version number: GHS 1.0

date of compilation: 2020-04-07

SECTION 4: First aid measures4.1

description of first aid measuresgeneral notes
do not leave affected person unattended. remove victim out of the danger area. keep affected person warm, still andcovered. take off immediately all contaminated clothing. in all cases of doubt, or when symptoms persist, seek medical advice. in case of unconsciousness place person in the recovery position. Never give anything by mouth.

following inhalation
if breathing is irregular or stopped, immediately seek medical assistance and start first aid actions. provide fresh air.

following skin contact
wash with plenty of soap and water.

following eye contact
remove contact lenses, if present and easy to do. Continue rinsing. irrigate copiously with clean, fresh water for at least 10
minutes, holding the eyelids apart.

following ingestionrinse mouth with water (only if the person is conscious). do NOT induce vomiting.

4.2

most important symptoms and effects, both acute and delayed
symptoms and effects are not known to date.

4.3

indication of any immediate medical attention and special treatment needed
none

SECTION 5: Firefighting measures
5.1

extinguishing media
suitable extinguishing media
water spray, BC-powder, carbon dioxide (CO2)

unsuitable extinguishing media
water jet

5.2

special hazards arising from the substance or mixture
hazardous combustion products
nitrogen oxides (NOx)

5.3

advice for firefightersin case of fire and/or explosion do not breathe fumes. co-ordinate firefighting measures to the fire surroundings. do not allow firefighting water to enter drains or water courses. collect contaminated firefighting water separately. fight fire withnormal precautions from a reasonable distance.

SECTION 6: Accidental release measures
6.1

personal precautions, protective equipment and emergency procedures
for non-emergency personnel
remove persons to safety.

for emergency responders
wear breathing apparatus if exposed to vapours/dust/spray/gases.

6.2

environmental precautions
keep away from drains, surface and ground water. retain contaminated washing water and dispose of it.

United Kingdom: en

page: 2 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

Unmethylated spike-in control
version number: GHS 1.0

6.3

date of compilation: 2020-04-07

methods and material for containment and cleaning up
advice on how to contain a spillcovering of drains

advice on how to clean up a spill
wipe up with absorbent material (e.g. cloth, fleece). collect spillage: sawdust, kieselgur (diatomite), sand, universal binder

appropriate containment techniques
use of adsorbent materials.

other information relating to spills and releases
place in appropriate containers for disposal. ventilate affected area.

6.4

reference to other sections
hazardous combustion products: see section 5. personal protective equipment: see section 8. incompatible materials: seesection 10. disposal considerations: see section 13.

SECTION 7: Handling and storage
7.1

precautions for safe handlingrecommendations- measures to prevent fire as well as aerosol and dust generation
use local and general ventilation. use only in well-ventilated areas.

advice on general occupational hygiene
wash hands after use. do not eat, drink and smoke in work areas. remove contaminated clothing and protective equipment
before entering eating areas. never keep food or drink in the vicinity of chemicals. never place chemicals in containers thatare normally used for food or drink. keep away from food, drink and animal feedingstuffs.

7.2

conditions for safe storage, including any incompatibilities
control of effects
protect against external exposure, such as
frost

7.3

specific end use(s)see section 16 for a general overview.

SECTION 8: Exposure controls/personal protection
8.1

control parameters
this information is not available.

8.2

exposure controls
appropriate engineering controls
general ventilation.

individual protection measures (personal protective equipment)eye/face protection
wear eye/face protection.

United Kingdom: en

page: 3 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

Unmethylated spike-in control
version number: GHS 1.0

date of compilation: 2020-04-07

skin protection- hand protection
wear suitable gloves. chemical protection gloves are suitable, which are tested according to EN 374. check leak-tightness/
impermeability prior to use. in the case of wanting to use the gloves again, clean them before taking off and air them well.
for special purposes, it is recommended to check the resistance to chemicals of the protective gloves mentioned above together with the supplier of these gloves.

- other protection measurestake recovery periods for skin regeneration. preventive skin protection (barrier creams/ointments) is recommended. wash
hands thoroughly after handling.

respiratory protection
in case of inadequate ventilation wear respiratory protection.

environmental exposure controls
use appropriate container to avoid environmental contamination. keep away from drains, surface and ground water.

SECTION 9: Physical and chemical properties
9.1

information on basic physical and chemical properties
appearancephysical stateliquidcolourcolourlessodour

odourlessother safety parameters
pH (value)

not determinedmelting point/freezing point

not determined

initial boiling point and boiling range

not determinedflash point

not determined

evaporation rate

not determined

flammability (solid, gas)

not relevant, (fluid)

explosive limits

not determinedvapour pressure

not determined

density

not determinedvapour density

this information is not available

relative density

information on this property is not available

solubility(ies)not determinedpartition coefficient- n-octanol/water (log KOW)
United Kingdom: enthis information is not available
page: 4 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

Unmethylated spike-in control
version number: GHS 1.0

9.2

date of compilation: 2020-04-07

auto-ignition temperature

not determinedviscosity

not determined

explosive properties

none

oxidising properties

none

other information

there is no additional information

SECTION 10: Stability and reactivity
10.1

reactivity
concerning incompatibility: see below "Conditions to avoid" and "Incompatible materials".

10.2

chemical stability
the material is stable under normal ambient and anticipated storage and handling conditions of temperature and pressure.

10.3

possibility of hazardous reactions
no known hazardous reactions.

10.4

conditions to avoid
there are no specific conditions known which have to be avoided.

10.5

incompatible materials
there is no additional information.

10.6

hazardous decomposition products
reasonably anticipated hazardous decomposition products produced as a result of use, storage, spill and heating are notknown. hazardous combustion products: see section 5.

SECTION 11: Toxicological information
11.1

information on toxicological effects
test data are not available for the complete mixture.

classification procedurethe method for classification of the mixture is based on ingredients of the mixture (additivity formula).

classification according to GHS (1272/2008/EC, CLP)
this mixture does not meet the criteria for classification in accordance with Regulation No 1272/2008/EC.

acute toxicity
shall not be classified as acutely toxic.

skin corrosion/irritation
shall not be classified as corrosive/irritant to skin.

serious eye damage/eye irritation
shall not be classified as seriously damaging to the eye or eye irritant.

respiratory or skin sensitisation
shall not be classified as a respiratory or skin sensitiser.

germ cell mutagenicity
shall not be classified as germ cell mutagenic.

United Kingdom: en

page: 5 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

Unmethylated spike-in control
version number: GHS 1.0

date of compilation: 2020-04-07

carcinogenicity
shall not be classified as carcinogenic.

reproductive toxicity
shall not be classified as a reproductive toxicant.

specific target organ toxicity - single exposure
shall not be classified as a specific target organ toxicant (single exposure).

specific target organ toxicity - repeated exposure
shall not be classified as a specific target organ toxicant (repeated exposure).

aspiration hazard
shall not be classified as presenting an aspiration hazard.

SECTION 12: Ecological information
12.1

toxicity
shall not be classified as hazardous to the aquatic environment.

12.2

persistence and degradability
data are not available.

12.3

bioaccumulative potential
data are not available.

12.4

mobility in soil
data are not available.

12.5

results of PBT and vPvB assessment
data are not available.

12.6

other adverse effects
data are not available.

SECTION 13: Disposal considerations
13.1

waste treatment methods
sewage disposal-relevant information
do not empty into drains. avoid release to the environment. Refer to special instructions/safety data sheets.

waste treatment of containers/packagingscompletely emptied packages can be recycled. handle contaminated packages in the same way as the substance itself.

remarks
please consider the relevant national or regional provisions. waste shall be separated into the categories that can behandled separately by the local or national waste management facilities.

United Kingdom: en

page: 6 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

Unmethylated spike-in control
version number: GHS 1.0

date of compilation: 2020-04-07

SECTION 14: Transport information
14.1

UN numbernot subject to transport regulations

14.2

UN proper shipping namenot relevant

14.3

transport hazard class(es)

none

14.4

packing group

not assigned to a packing group

14.5

environmental hazards

non-environmentally hazardous acc. to the dangerous goods regulations

14.6

special precautions for user
there is no additional information.

14.7

transport in bulk according to Annex II of MARPOL and the IBC Codethe cargo is not intended to be carried in bulk.

Information for each of the UN Model Regulationstransport of dangerous goods by road, rail and inland waterway (ADR/RID/ADN)
not subject to ADR, RID and ADN.

International Maritime Dangerous Goods Code (IMDG)
not subject to IMDG.

International Civil Aviation Organization (ICAO-IATA/DGR)
not subject to ICAO-IATA.

SECTION 15: Regulatory information
15.1

safety, health and environmental regulations/legislation specific for the substance or mixture

15.2

Chemical Safety Assessment
chemical safety assessments for substances in this mixture were not carried out.

SECTION 16: Other informationabbreviations and acronyms
abbr.

descriptions of used abbreviations

ADN

Accord européen relatif au transport international des marchandises dangereuses par voies de navigation
intérieures (European Agreement concerning the International Carriage of Dangerous Goods by Inland Waterways)

ADR

Accord européen relatif au transport international des marchandises dangereuses par route (European Agreement concerning the International Carriage of Dangerous Goods by Road)

CLP

Regulation (EC) No 1272/2008 on classification, labelling and packaging of substances and mixtures

DGR

Dangerous Goods Regulations (see IATA/DGR)

GHS"Globally Harmonized System of Classification and Labelling of Chemicals" developed by the United Nations

IATA

International Air Transport Association

IATA/DGR

Dangerous Goods Regulations (DGR) for the air transport (IATA)ICAOInternational Civil Aviation Organization

IMDG

International Maritime Dangerous Goods CodeUnited Kingdom: en

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Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

Unmethylated spike-in control
version number: GHS 1.0

date of compilation: 2020-04-07

abbr.

descriptions of used abbreviations

MARPOLInternational Convention for the Prevention of Pollution from Ships (abbr. of "Marine Pollutant")

PBT

Persistent, Bioaccumulative and Toxic

REACH

Registration, Evaluation, Authorisation and Restriction of Chemicals

RID

Règlement concernant le transport International ferroviaire des marchandises Dangereuses (Regulations concerning the International carriage of Dangerous goods by Rail)vPvB

Very Persistent and very Bioaccumulative

key literature references and sources for data
Regulation (EC) No 1272/2008 on classification, labelling and packaging of substances and mixtures. Regulation (EC) No.
1907/2006 (REACH), amended by 2015/830/EU.
transport of dangerous goods by road, rail and inland waterway (ADR/RID/ADN). International Maritime Dangerous Goods
Code (IMDG). Dangerous Goods Regulations (DGR) for the air transport (IATA).

classification procedurephysical and chemical properties: the classification is based on tested mixture.
health hazards, environmental hazards: the method for classification of the mixture is based on ingredients of the mixture(additivity formula).

disclaimer
this information is based upon the present state of our knowledge. this SDS has been compiled and is solely intended for thisproduct.

United Kingdom: en

page: 8 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

MagWash buffer-1
version number: GHS 1.0

date of compilation: 2020-04-07

SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1

1.2

product identifiertrade name

MagWash buffer-1

registration number (REACH)

not relevant (mixture)

relevant identified uses of the substance or mixture and uses advised against
relevant identified uses

1.3

for research use only, not for use in diagnostic ortherapeutic procedures.

details of the supplier of the safety data sheet
Diagenode SA
LIEGE SCIENCE PARK Rue du Bois Saint-Jean, 34102 Seraing
Belgium
telephone: +32 4 364 20 50
e-mail: info@diagenode.com

1.4

emergency telephone number
emergency information service+32 4 364 20 50
this number is only available during the following office hours: Mon-Fri 09:00 AM - 05:00 PM

poison centre
country

nametelephone

United Kingdom

National Poisons Information Service

111

SECTION 2: Hazards identification
2.1

classification of the substance or mixture
classification according to Regulation (EC) No 1272/2008 (CLP)sectionhazard class

categoryhazard class and category

hazard statement

3.3

serious eye damage/eye irritation

2

Eye Irrit. 2

H319

4.1C

hazardous to the aquatic environment - chronic hazard

3

Aquatic Chronic 3

H412

for full text of abbreviations: see SECTION 16.

the most important adverse physicochemical, human health and environmental effects
spillage and fire water can cause pollution of watercourses.

2.2

label elements
labelling according to Regulation (EC) No 1272/2008 (CLP)- signal word

warning- pictograms
GHS07

United Kingdom: en

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Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

MagWash buffer-1
version number: GHS 1.0

date of compilation: 2020-04-07- hazard statements
H319
H412

causes serious eye irritation.
harmful to aquatic life with long lasting effects.

- precautionary statements
P273
P280
P305+P351+P338
P337+P313
P501

2.3

avoid release to the environment.
wear protective gloves/protective clothing/eye protection/face protection.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present andeasy to do. Continue rinsing.
if eye irritation persists: Get medical advice/attention.
dispose of contents/container to industrial combustion plant.

other hazards
results of PBT and vPvB assessment
this mixture does not contain any substances that are assessed to be a PBT or a vPvB.

SECTION 3: Composition/information on ingredients
3.1

substances
not relevant (mixture)

3.2

mixturesdescription of the mixturename of substanceidentifier

wt%classification acc. to GHS

Triton X-100

CAS No9002-93-1≤2

Acute Tox. 4 / H302
Skin Irrit. 2 / H315
Eye Dam. 1 / H318
Aquatic Acute 1 / H400
Aquatic Chronic 1 / H410

EC No
618-344-0

pictograms

for full text of abbreviations: see SECTION 16.

SECTION 4: First aid measures4.1

description of first aid measuresgeneral notes
do not leave affected person unattended. remove victim out of the danger area. keep affected person warm, still andcovered. take off immediately all contaminated clothing. in all cases of doubt, or when symptoms persist, seek medical advice. in case of unconsciousness place person in the recovery position. Never give anything by mouth.

following inhalation
if breathing is irregular or stopped, immediately seek medical assistance and start first aid actions. provide fresh air.

following skin contact
wash with plenty of soap and water.

following eye contact
remove contact lenses, if present and easy to do. Continue rinsing. irrigate copiously with clean, fresh water for at least 10
minutes, holding the eyelids apart.

following ingestionrinse mouth with water (only if the person is conscious). do NOT induce vomiting.

4.2

most important symptoms and effects, both acute and delayed
symptoms and effects are not known to date.

4.3

indication of any immediate medical attention and special treatment needed
none

United Kingdom: en

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Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

MagWash buffer-1
version number: GHS 1.0

date of compilation: 2020-04-07

SECTION 5: Firefighting measures
5.1

extinguishing media
suitable extinguishing media
water spray, BC-powder, carbon dioxide (CO2)

unsuitable extinguishing media
water jet

5.2

special hazards arising from the substance or mixture
hazardous combustion products
nitrogen oxides (NOx)

5.3

advice for firefightersin case of fire and/or explosion do not breathe fumes. co-ordinate firefighting measures to the fire surroundings. do not allow firefighting water to enter drains or water courses. collect contaminated firefighting water separately. fight fire withnormal precautions from a reasonable distance.

SECTION 6: Accidental release measures
6.1

personal precautions, protective equipment and emergency procedures
for non-emergency personnel
remove persons to safety.

for emergency responders
wear breathing apparatus if exposed to vapours/dust/spray/gases.

6.2

environmental precautions
keep away from drains, surface and ground water. retain contaminated washing water and dispose of it.

6.3

methods and material for containment and cleaning up
advice on how to contain a spillcovering of drains

advice on how to clean up a spill
wipe up with absorbent material (e.g. cloth, fleece). collect spillage: sawdust, kieselgur (diatomite), sand, universal binder

appropriate containment techniques
use of adsorbent materials.

other information relating to spills and releases
place in appropriate containers for disposal. ventilate affected area.

6.4

reference to other sections
hazardous combustion products: see section 5. personal protective equipment: see section 8. incompatible materials: seesection 10. disposal considerations: see section 13.

United Kingdom: en

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Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

MagWash buffer-1
version number: GHS 1.0

date of compilation: 2020-04-07

SECTION 7: Handling and storage
7.1

precautions for safe handlingrecommendations- measures to prevent fire as well as aerosol and dust generation
use local and general ventilation. use only in well-ventilated areas.

advice on general occupational hygiene
wash hands after use. do not eat, drink and smoke in work areas. remove contaminated clothing and protective equipment
before entering eating areas. never keep food or drink in the vicinity of chemicals. never place chemicals in containers thatare normally used for food or drink. keep away from food, drink and animal feedingstuffs.

7.2

conditions for safe storage, including any incompatibilities
control of effects
protect against external exposure, such as
frost

7.3

specific end use(s)see section 16 for a general overview.

SECTION 8: Exposure controls/personal protection
8.1

control parameters
this information is not available.

8.2

exposure controls
appropriate engineering controls
general ventilation.

individual protection measures (personal protective equipment)eye/face protection
wear eye/face protection.

skin protection- hand protection
wear suitable gloves. chemical protection gloves are suitable, which are tested according to EN 374. check leak-tightness/
impermeability prior to use. in the case of wanting to use the gloves again, clean them before taking off and air them well.
for special purposes, it is recommended to check the resistance to chemicals of the protective gloves mentioned above together with the supplier of these gloves.

- other protection measurestake recovery periods for skin regeneration. preventive skin protection (barrier creams/ointments) is recommended. wash
hands thoroughly after handling.

respiratory protection
in case of inadequate ventilation wear respiratory protection.

environmental exposure controls
use appropriate container to avoid environmental contamination. keep away from drains, surface and ground water.

United Kingdom: en

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Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

MagWash buffer-1
version number: GHS 1.0

date of compilation: 2020-04-07

SECTION 9: Physical and chemical properties
9.1

information on basic physical and chemical properties
appearancephysical stateliquidcolourcolourlessodour

odourlessother safety parameters
pH (value)

not determinedmelting point/freezing point

not determined

initial boiling point and boiling range

not determinedflash point

not determined

evaporation rate

not determined

flammability (solid, gas)

not relevant, (fluid)

explosive limits

not determinedvapour pressure

not determined

density

not determinedvapour density

this information is not available

relative density

information on this property is not available

solubility(ies)not determinedpartition coefficient9.2- n-octanol/water (log KOW)

this information is not available

auto-ignition temperature

not determinedviscosity

not determined

explosive properties

none

oxidising properties

none

other information

there is no additional information

United Kingdom: en

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Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

MagWash buffer-1
version number: GHS 1.0

date of compilation: 2020-04-07

SECTION 10: Stability and reactivity
10.1

reactivity
concerning incompatibility: see below "Conditions to avoid" and "Incompatible materials".

10.2

chemical stability
see below "Conditions to avoid".

10.3

possibility of hazardous reactions
no known hazardous reactions.

10.4

conditions to avoid
there are no specific conditions known which have to be avoided.

10.5

incompatible materials
there is no additional information.

10.6

hazardous decomposition products
reasonably anticipated hazardous decomposition products produced as a result of use, storage, spill and heating are notknown. hazardous combustion products: see section 5.

SECTION 11: Toxicological information
11.1

information on toxicological effects
test data are not available for the complete mixture.

classification procedurethe method for classification of the mixture is based on ingredients of the mixture (additivity formula).

classification according to GHS (1272/2008/EC, CLP)
acute toxicity
shall not be classified as acutely toxic.

skin corrosion/irritation
shall not be classified as corrosive/irritant to skin.

serious eye damage/eye irritation
causes serious eye irritation.

respiratory or skin sensitisation
shall not be classified as a respiratory or skin sensitiser.

germ cell mutagenicity
shall not be classified as germ cell mutagenic.

carcinogenicity
shall not be classified as carcinogenic.

reproductive toxicity
shall not be classified as a reproductive toxicant.

specific target organ toxicity - single exposure
shall not be classified as a specific target organ toxicant (single exposure).

specific target organ toxicity - repeated exposure
shall not be classified as a specific target organ toxicant (repeated exposure).

United Kingdom: en

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Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

MagWash buffer-1
version number: GHS 1.0

date of compilation: 2020-04-07

aspiration hazard
shall not be classified as presenting an aspiration hazard.

SECTION 12: Ecological information
12.1

toxicity
harmful to aquatic life with long lasting effects.

12.2

persistence and degradability
data are not available.

12.3

bioaccumulative potential
data are not available.

12.4

mobility in soil
data are not available.

12.5

results of PBT and vPvB assessment
data are not available.

12.6

other adverse effects
data are not available.

SECTION 13: Disposal considerations
13.1

waste treatment methods
sewage disposal-relevant information
do not empty into drains. avoid release to the environment. Refer to special instructions/safety data sheets.

waste treatment of containers/packagingscompletely emptied packages can be recycled. handle contaminated packages in the same way as the substance itself.

remarks
please consider the relevant national or regional provisions. waste shall be separated into the categories that can behandled separately by the local or national waste management facilities.

SECTION 14: Transport information
14.1

UN numbernot subject to transport regulations

14.2

UN proper shipping namenot relevant

14.3

transport hazard class(es)not assigned

14.4

packing group

not assigned

14.5

environmental hazards

non-environmentally hazardous acc. to the dangerous goods regulations

14.6

special precautions for user
there is no additional information.

14.7

transport in bulk according to Annex II of MARPOL and the IBC Codethe cargo is not intended to be carried in bulk.

United Kingdom: en

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Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

MagWash buffer-1
version number: GHS 1.0

date of compilation: 2020-04-07

Information for each of the UN Model Regulationstransport of dangerous goods by road, rail and inland waterway (ADR/RID/ADN)
not subject to ADR. not subject to RID.

European Agreement concerning the International Carriage of Dangerous Goods by Inland
Waterways (ADN)
identifier number

9006

proper shipping name

ENVIRONMENTALLY HAZARDOUS SUBSTANCE, LIQUID, N.O.S.

class

9

number of cones/blue lights

0International Maritime Dangerous Goods Code (IMDG)
not subject to IMDG.

International Civil Aviation Organization (ICAO-IATA/DGR)
not subject to ICAO-IATA.

SECTION 15: Regulatory information
15.1

safety, health and environmental regulations/legislation specific for the substance or mixture

15.2

Chemical Safety Assessment
chemical safety assessments for substances in this mixture were not carried out.

SECTION 16: Other informationabbreviations and acronyms
abbr.

descriptions of used abbreviations

Acute Tox.

Acute toxicity

ADN

Accord européen relatif au transport international des marchandises dangereuses par voies de navigation
intérieures (European Agreement concerning the International Carriage of Dangerous Goods by Inland Waterways)

ADR

Accord européen relatif au transport international des marchandises dangereuses par route (European Agreement concerning the International Carriage of Dangerous Goods by Road)

Aquatic Acute

Hazardous to the aquatic environment - acute hazard

Aquatic Chronic

Hazardous to the aquatic environment - chronic hazard

CAS

Chemical Abstracts Service (service that maintains the most comprehensive list of chemical substances)

CLP

Regulation (EC) No 1272/2008 on classification, labelling and packaging of substances and mixtures

DGR

Dangerous Goods Regulations (see IATA/DGR)

EC No

The EC Inventory (EINECS, ELINCS and the NLP-list) is the source for the seven-digit EC number, an identifierof substances commercially available within the EU (European Union)

EINECS

European Inventory of Existing Commercial Chemical Substances

ELINCS

European List of Notified Chemical Substances

Eye Dam.

Seriously damaging to the eye

Eye Irrit.

Irritant to the eye

GHS"Globally Harmonized System of Classification and Labelling of Chemicals" developed by the United Nations

United Kingdom: en

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Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

MagWash buffer-1
version number: GHS 1.0

date of compilation: 2020-04-07

abbr.

descriptions of used abbreviations

IATA

International Air Transport Association

IATA/DGR

Dangerous Goods Regulations (DGR) for the air transport (IATA)ICAOInternational Civil Aviation Organization

IMDG

International Maritime Dangerous Goods Codeindex NoThe Index number is the identification code given to the substance in Part 3 of Annex VI to Regulation (EC) No
1272/2008

MARPOLInternational Convention for the Prevention of Pollution from Ships (abbr. of "Marine Pollutant")

NLP

No-Longer Polymer

PBT

Persistent, Bioaccumulative and Toxic

REACH

Registration, Evaluation, Authorisation and Restriction of Chemicals

RID

Règlement concernant le transport International ferroviaire des marchandises Dangereuses (Regulations concerning the International carriage of Dangerous goods by Rail)Skin Corr.

Corrosive to skin

Skin Irrit.

Irritant to skinvPvB

Very Persistent and very Bioaccumulative

key literature references and sources for data
Regulation (EC) No 1272/2008 on classification, labelling and packaging of substances and mixtures. Regulation (EC) No.
1907/2006 (REACH), amended by 2015/830/EU.
transport of dangerous goods by road, rail and inland waterway (ADR/RID/ADN). International Maritime Dangerous Goods
Code (IMDG). Dangerous Goods Regulations (DGR) for the air transport (IATA).

classification procedurephysical and chemical properties: the classification is based on tested mixture.
health hazards, environmental hazards: the method for classification of the mixture is based on ingredients of the mixture(additivity formula).

list of relevant phrases (code and full text as stated in chapter 2 and 3)
code

text

H302

Harmful if swallowed.

H315

Causes skin irritation.

H318

Causes serious eye damage.

H319

Causes serious eye irritation.

H400

Very toxic to aquatic life.

H410

Very toxic to aquatic life with long lasting effects.

H412

Harmful to aquatic life with long lasting effects.

disclaimer
this information is based upon the present state of our knowledge. this SDS has been compiled and is solely intended for thisproduct.

United Kingdom: en

page: 9 / 9Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

MagWash buffer-2
version number: GHS 1.0

date of compilation: 2020-04-07

SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1

1.2

product identifiertrade name

MagWash buffer-2

registration number (REACH)

not relevant (mixture)

relevant identified uses of the substance or mixture and uses advised against
relevant identified uses

1.3

for research use only, not for use in diagnostic ortherapeutic procedures.

details of the supplier of the safety data sheet
Diagenode SA
LIEGE SCIENCE PARK Rue du Bois Saint-Jean, 34102 Seraing
Belgium
telephone: +32 4 364 20 50
e-mail: info@diagenode.com

1.4

emergency telephone number
emergency information service+32 4 364 20 50
this number is only available during the following office hours: Mon-Fri 09:00 AM - 05:00 PM

poison centre
country

nametelephone

United Kingdom

National Poisons Information Service

111

SECTION 2: Hazards identification
2.1

classification of the substance or mixture
classification according to Regulation (EC) No 1272/2008 (CLP)
this mixture does not meet the criteria for classification in accordance with Regulation No 1272/2008/EC.

2.2

label elements
labelling according to Regulation (EC) No 1272/2008 (CLP)
not required

2.3

other hazards
results of PBT and vPvB assessment
this mixture does not contain any substances that are assessed to be a PBT or a vPvB.

SECTION 3: Composition/information on ingredients
3.1

substances
not relevant (mixture)

3.2

mixturesdescription of the mixtureThis mixture does not contain any potentially hazardous products.

United Kingdom: en

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Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

MagWash buffer-2
version number: GHS 1.0

date of compilation: 2020-04-07

SECTION 4: First aid measures4.1

description of first aid measuresgeneral notes
do not leave affected person unattended. remove victim out of the danger area. keep affected person warm, still andcovered. take off immediately all contaminated clothing. in all cases of doubt, or when symptoms persist, seek medical advice. in case of unconsciousness place person in the recovery position. Never give anything by mouth.

following inhalation
if breathing is irregular or stopped, immediately seek medical assistance and start first aid actions. provide fresh air.

following skin contact
wash with plenty of soap and water.

following eye contact
remove contact lenses, if present and easy to do. Continue rinsing. irrigate copiously with clean, fresh water for at least 10
minutes, holding the eyelids apart.

following ingestionrinse mouth with water (only if the person is conscious). do NOT induce vomiting.

4.2

most important symptoms and effects, both acute and delayed
symptoms and effects are not known to date.

4.3

indication of any immediate medical attention and special treatment needed
none

SECTION 5: Firefighting measures
5.1

extinguishing media
suitable extinguishing media
water spray, BC-powder, carbon dioxide (CO2)

unsuitable extinguishing media
water jet

5.2

special hazards arising from the substance or mixture
hazardous combustion products
nitrogen oxides (NOx)

5.3

advice for firefightersin case of fire and/or explosion do not breathe fumes. co-ordinate firefighting measures to the fire surroundings. do not allow firefighting water to enter drains or water courses. collect contaminated firefighting water separately. fight fire withnormal precautions from a reasonable distance.

SECTION 6: Accidental release measures
6.1

personal precautions, protective equipment and emergency procedures
for non-emergency personnel
remove persons to safety.

for emergency responders
wear breathing apparatus if exposed to vapours/dust/spray/gases.

6.2

environmental precautions
keep away from drains, surface and ground water. retain contaminated washing water and dispose of it.

United Kingdom: en

page: 2 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

MagWash buffer-2
version number: GHS 1.0

6.3

date of compilation: 2020-04-07

methods and material for containment and cleaning up
advice on how to contain a spillcovering of drains

advice on how to clean up a spill
wipe up with absorbent material (e.g. cloth, fleece). collect spillage: sawdust, kieselgur (diatomite), sand, universal binder

appropriate containment techniques
use of adsorbent materials.

other information relating to spills and releases
place in appropriate containers for disposal. ventilate affected area.

6.4

reference to other sections
hazardous combustion products: see section 5. personal protective equipment: see section 8. incompatible materials: seesection 10. disposal considerations: see section 13.

SECTION 7: Handling and storage
7.1

precautions for safe handlingrecommendations- measures to prevent fire as well as aerosol and dust generation
use local and general ventilation. use only in well-ventilated areas.

advice on general occupational hygiene
wash hands after use. do not eat, drink and smoke in work areas. remove contaminated clothing and protective equipment
before entering eating areas. never keep food or drink in the vicinity of chemicals. never place chemicals in containers thatare normally used for food or drink. keep away from food, drink and animal feedingstuffs.

7.2

conditions for safe storage, including any incompatibilities
control of effects
protect against external exposure, such as
frost

7.3

specific end use(s)see section 16 for a general overview.

SECTION 8: Exposure controls/personal protection
8.1

control parameters
this information is not available.

8.2

exposure controls
appropriate engineering controls
general ventilation.

individual protection measures (personal protective equipment)eye/face protection
wear eye/face protection.

United Kingdom: en

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Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

MagWash buffer-2
version number: GHS 1.0

date of compilation: 2020-04-07

skin protection- hand protection
wear suitable gloves. chemical protection gloves are suitable, which are tested according to EN 374. check leak-tightness/
impermeability prior to use. in the case of wanting to use the gloves again, clean them before taking off and air them well.
for special purposes, it is recommended to check the resistance to chemicals of the protective gloves mentioned above together with the supplier of these gloves.

- other protection measurestake recovery periods for skin regeneration. preventive skin protection (barrier creams/ointments) is recommended. wash
hands thoroughly after handling.

respiratory protection
in case of inadequate ventilation wear respiratory protection.

environmental exposure controls
use appropriate container to avoid environmental contamination. keep away from drains, surface and ground water.

SECTION 9: Physical and chemical properties
9.1

information on basic physical and chemical properties
appearancephysical stateliquidcolourcolourlessodour

odourlessother safety parameters
pH (value)

not determinedmelting point/freezing point

not determined

initial boiling point and boiling range

not determinedflash point

not determined

evaporation rate

not determined

flammability (solid, gas)

not relevant, (fluid)

explosive limits

not determinedvapour pressure

not determined

density

not determinedvapour density

this information is not available

relative density

information on this property is not available

solubility(ies)not determinedpartition coefficient- n-octanol/water (log KOW)
United Kingdom: enthis information is not available
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Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

MagWash buffer-2
version number: GHS 1.0

9.2

date of compilation: 2020-04-07

auto-ignition temperature

not determinedviscosity

not determined

explosive properties

none

oxidising properties

none

other information

there is no additional information

SECTION 10: Stability and reactivity
10.1

reactivity
concerning incompatibility: see below "Conditions to avoid" and "Incompatible materials".

10.2

chemical stability
the material is stable under normal ambient and anticipated storage and handling conditions of temperature and pressure.

10.3

possibility of hazardous reactions
no known hazardous reactions.

10.4

conditions to avoid
there are no specific conditions known which have to be avoided.

10.5

incompatible materials
there is no additional information.

10.6

hazardous decomposition products
reasonably anticipated hazardous decomposition products produced as a result of use, storage, spill and heating are notknown. hazardous combustion products: see section 5.

SECTION 11: Toxicological information
11.1

information on toxicological effects
test data are not available for the complete mixture.

classification procedurethe method for classification of the mixture is based on ingredients of the mixture (additivity formula).

classification according to GHS (1272/2008/EC, CLP)
this mixture does not meet the criteria for classification in accordance with Regulation No 1272/2008/EC.

acute toxicity
shall not be classified as acutely toxic.

skin corrosion/irritation
shall not be classified as corrosive/irritant to skin.

serious eye damage/eye irritation
shall not be classified as seriously damaging to the eye or eye irritant.

respiratory or skin sensitisation
shall not be classified as a respiratory or skin sensitiser.

germ cell mutagenicity
shall not be classified as germ cell mutagenic.

United Kingdom: en

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Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

MagWash buffer-2
version number: GHS 1.0

date of compilation: 2020-04-07

carcinogenicity
shall not be classified as carcinogenic.

reproductive toxicity
shall not be classified as a reproductive toxicant.

specific target organ toxicity - single exposure
shall not be classified as a specific target organ toxicant (single exposure).

specific target organ toxicity - repeated exposure
shall not be classified as a specific target organ toxicant (repeated exposure).

aspiration hazard
shall not be classified as presenting an aspiration hazard.

SECTION 12: Ecological information
12.1

toxicity
shall not be classified as hazardous to the aquatic environment.

12.2

persistence and degradability
data are not available.

12.3

bioaccumulative potential
data are not available.

12.4

mobility in soil
data are not available.

12.5

results of PBT and vPvB assessment
data are not available.

12.6

other adverse effects
data are not available.

SECTION 13: Disposal considerations
13.1

waste treatment methods
sewage disposal-relevant information
do not empty into drains. avoid release to the environment. Refer to special instructions/safety data sheets.

waste treatment of containers/packagingscompletely emptied packages can be recycled. handle contaminated packages in the same way as the substance itself.

remarks
please consider the relevant national or regional provisions. waste shall be separated into the categories that can behandled separately by the local or national waste management facilities.

United Kingdom: en

page: 6 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

MagWash buffer-2
version number: GHS 1.0

date of compilation: 2020-04-07

SECTION 14: Transport information
14.1

UN numbernot subject to transport regulations

14.2

UN proper shipping namenot relevant

14.3

transport hazard class(es)

none

14.4

packing group

not assigned to a packing group

14.5

environmental hazards

non-environmentally hazardous acc. to the dangerous goods regulations

14.6

special precautions for user
there is no additional information.

14.7

transport in bulk according to Annex II of MARPOL and the IBC Codethe cargo is not intended to be carried in bulk.

Information for each of the UN Model Regulationstransport of dangerous goods by road, rail and inland waterway (ADR/RID/ADN)
not subject to ADR, RID and ADN.

International Maritime Dangerous Goods Code (IMDG)
not subject to IMDG.

International Civil Aviation Organization (ICAO-IATA/DGR)
not subject to ICAO-IATA.

SECTION 15: Regulatory information
15.1

safety, health and environmental regulations/legislation specific for the substance or mixture

15.2

Chemical Safety Assessment
chemical safety assessments for substances in this mixture were not carried out.

SECTION 16: Other informationabbreviations and acronyms
abbr.

descriptions of used abbreviations

ADN

Accord européen relatif au transport international des marchandises dangereuses par voies de navigation
intérieures (European Agreement concerning the International Carriage of Dangerous Goods by Inland Waterways)

ADR

Accord européen relatif au transport international des marchandises dangereuses par route (European Agreement concerning the International Carriage of Dangerous Goods by Road)

CLP

Regulation (EC) No 1272/2008 on classification, labelling and packaging of substances and mixtures

DGR

Dangerous Goods Regulations (see IATA/DGR)

GHS"Globally Harmonized System of Classification and Labelling of Chemicals" developed by the United Nations

IATA

International Air Transport Association

IATA/DGR

Dangerous Goods Regulations (DGR) for the air transport (IATA)ICAOInternational Civil Aviation Organization

IMDG

International Maritime Dangerous Goods CodeUnited Kingdom: en

page: 7 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

MagWash buffer-2
version number: GHS 1.0

date of compilation: 2020-04-07

abbr.

descriptions of used abbreviations

MARPOLInternational Convention for the Prevention of Pollution from Ships (abbr. of "Marine Pollutant")

PBT

Persistent, Bioaccumulative and Toxic

REACH

Registration, Evaluation, Authorisation and Restriction of Chemicals

RID

Règlement concernant le transport International ferroviaire des marchandises Dangereuses (Regulations concerning the International carriage of Dangerous goods by Rail)vPvB

Very Persistent and very Bioaccumulative

key literature references and sources for data
Regulation (EC) No 1272/2008 on classification, labelling and packaging of substances and mixtures. Regulation (EC) No.
1907/2006 (REACH), amended by 2015/830/EU.
transport of dangerous goods by road, rail and inland waterway (ADR/RID/ADN). International Maritime Dangerous Goods
Code (IMDG). Dangerous Goods Regulations (DGR) for the air transport (IATA).

classification procedurephysical and chemical properties: the classification is based on tested mixture.
health hazards, environmental hazards: the method for classification of the mixture is based on ingredients of the mixture(additivity formula).

disclaimer
this information is based upon the present state of our knowledge. this SDS has been compiled and is solely intended for thisproduct.

United Kingdom: en

page: 8 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

DNA Isolation Buffer (DIB)
version number: GHS 1.0

date of compilation: 2020-03-26

SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1

1.2

product identifiertrade nameDNA Isolation Buffer (DIB)

registration number (REACH)

not relevant (mixture)

relevant identified uses of the substance or mixture and uses advised against
relevant identified uses

1.3

for research use only, not for use in diagnostic ortherapeutic procedures.

details of the supplier of the safety data sheet
Diagenode SA
LIEGE SCIENCE PARK Rue du Bois Saint-Jean, 34102 Seraing
Belgium
telephone: +32 4 364 20 50
e-mail: info@diagenode.com

1.4

emergency telephone number
emergency information service+32 4 364 20 50
this number is only available during the following office hours: Mon-Fri 09:00 AM - 05:00 PM

poison centre
country

nametelephone

United Kingdom

National Poisons Information Service

111

SECTION 2: Hazards identification
2.1

classification of the substance or mixture
classification according to Regulation (EC) No 1272/2008 (CLP)
this mixture does not meet the criteria for classification in accordance with Regulation No 1272/2008/EC.

2.2

label elements
labelling according to Regulation (EC) No 1272/2008 (CLP)
not required

2.3

other hazards
results of PBT and vPvB assessment
this mixture does not contain any substances that are assessed to be a PBT or a vPvB.

SECTION 3: Composition/information on ingredients
3.1

substances
not relevant (mixture)

3.2

mixturesdescription of the mixtureThis mixture does not contain any potentially hazardous products.

United Kingdom: en

page: 1 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

DNA Isolation Buffer (DIB)
version number: GHS 1.0

date of compilation: 2020-03-26

SECTION 4: First aid measures4.1

description of first aid measuresgeneral notes
do not leave affected person unattended. remove victim out of the danger area. keep affected person warm, still andcovered. take off immediately all contaminated clothing. in all cases of doubt, or when symptoms persist, seek medical advice. in case of unconsciousness place person in the recovery position. Never give anything by mouth.

following inhalation
if breathing is irregular or stopped, immediately seek medical assistance and start first aid actions. provide fresh air.

following skin contact
wash with plenty of soap and water.

following eye contact
remove contact lenses, if present and easy to do. Continue rinsing. irrigate copiously with clean, fresh water for at least 10
minutes, holding the eyelids apart.

following ingestionrinse mouth with water (only if the person is conscious). do NOT induce vomiting.

4.2

most important symptoms and effects, both acute and delayed
symptoms and effects are not known to date.

4.3

indication of any immediate medical attention and special treatment needed
none

SECTION 5: Firefighting measures
5.1

extinguishing media
suitable extinguishing media
water spray, BC-powder, carbon dioxide (CO2)

unsuitable extinguishing media
water jet

5.2

special hazards arising from the substance or mixture
hazardous combustion products
nitrogen oxides (NOx)

5.3

advice for firefightersin case of fire and/or explosion do not breathe fumes. co-ordinate firefighting measures to the fire surroundings. do not allow firefighting water to enter drains or water courses. collect contaminated firefighting water separately. fight fire withnormal precautions from a reasonable distance.

SECTION 6: Accidental release measures
6.1

personal precautions, protective equipment and emergency procedures
for non-emergency personnel
remove persons to safety.

for emergency responders
wear breathing apparatus if exposed to vapours/dust/spray/gases.

6.2

environmental precautions
keep away from drains, surface and ground water. retain contaminated washing water and dispose of it.

United Kingdom: en

page: 2 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

DNA Isolation Buffer (DIB)
version number: GHS 1.0

6.3

date of compilation: 2020-03-26

methods and material for containment and cleaning up
advice on how to contain a spillcovering of drains

advice on how to clean up a spill
wipe up with absorbent material (e.g. cloth, fleece). collect spillage: sawdust, kieselgur (diatomite), sand, universal binder

appropriate containment techniques
use of adsorbent materials.

other information relating to spills and releases
place in appropriate containers for disposal. ventilate affected area.

6.4

reference to other sections
hazardous combustion products: see section 5. personal protective equipment: see section 8. incompatible materials: seesection 10. disposal considerations: see section 13.

SECTION 7: Handling and storage
7.1

precautions for safe handlingrecommendations- measures to prevent fire as well as aerosol and dust generation
use local and general ventilation. use only in well-ventilated areas.

advice on general occupational hygiene
wash hands after use. do not eat, drink and smoke in work areas. remove contaminated clothing and protective equipment
before entering eating areas. never keep food or drink in the vicinity of chemicals. never place chemicals in containers thatare normally used for food or drink. keep away from food, drink and animal feedingstuffs.

7.2

conditions for safe storage, including any incompatibilities
control of effects
protect against external exposure, such as
frost

7.3

specific end use(s)see section 16 for a general overview.

SECTION 8: Exposure controls/personal protection
8.1

control parameters
this information is not available.

8.2

exposure controls
appropriate engineering controls
general ventilation.

individual protection measures (personal protective equipment)eye/face protection
wear eye/face protection.

United Kingdom: en

page: 3 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

DNA Isolation Buffer (DIB)
version number: GHS 1.0

date of compilation: 2020-03-26

skin protection- hand protection
wear suitable gloves. chemical protection gloves are suitable, which are tested according to EN 374. check leak-tightness/
impermeability prior to use. in the case of wanting to use the gloves again, clean them before taking off and air them well.
for special purposes, it is recommended to check the resistance to chemicals of the protective gloves mentioned above together with the supplier of these gloves.

- other protection measurestake recovery periods for skin regeneration. preventive skin protection (barrier creams/ointments) is recommended. wash
hands thoroughly after handling.

respiratory protection
in case of inadequate ventilation wear respiratory protection.

environmental exposure controls
use appropriate container to avoid environmental contamination. keep away from drains, surface and ground water.

SECTION 9: Physical and chemical properties
9.1

information on basic physical and chemical properties
appearancephysical stateliquidcolourcolourlessodour

odourlessother safety parameters
pH (value)

not determinedmelting point/freezing point

not determined

initial boiling point and boiling range

not determinedflash point

not determined

evaporation rate

not determined

flammability (solid, gas)

not relevant, (fluid)

explosive limits

not determinedvapour pressure

not determined

density

not determinedvapour density

this information is not available

relative density

information on this property is not available

solubility(ies)not determinedpartition coefficient- n-octanol/water (log KOW)
United Kingdom: enthis information is not available
page: 4 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

DNA Isolation Buffer (DIB)
version number: GHS 1.0

9.2

date of compilation: 2020-03-26

auto-ignition temperature

not determinedviscosity

not determined

explosive properties

none

oxidising properties

none

other information

there is no additional information

SECTION 10: Stability and reactivity
10.1

reactivity
concerning incompatibility: see below "Conditions to avoid" and "Incompatible materials".

10.2

chemical stability
the material is stable under normal ambient and anticipated storage and handling conditions of temperature and pressure.

10.3

possibility of hazardous reactions
no known hazardous reactions.

10.4

conditions to avoid
there are no specific conditions known which have to be avoided.

10.5

incompatible materials
there is no additional information.

10.6

hazardous decomposition products
reasonably anticipated hazardous decomposition products produced as a result of use, storage, spill and heating are notknown. hazardous combustion products: see section 5.

SECTION 11: Toxicological information
11.1

information on toxicological effects
test data are not available for the complete mixture.

classification procedurethe method for classification of the mixture is based on ingredients of the mixture (additivity formula).

classification according to GHS (1272/2008/EC, CLP)
this mixture does not meet the criteria for classification in accordance with Regulation No 1272/2008/EC.

acute toxicity
shall not be classified as acutely toxic.

skin corrosion/irritation
shall not be classified as corrosive/irritant to skin.

serious eye damage/eye irritation
shall not be classified as seriously damaging to the eye or eye irritant.

respiratory or skin sensitisation
shall not be classified as a respiratory or skin sensitiser.

germ cell mutagenicity
shall not be classified as germ cell mutagenic.

United Kingdom: en

page: 5 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

DNA Isolation Buffer (DIB)
version number: GHS 1.0

date of compilation: 2020-03-26

carcinogenicity
shall not be classified as carcinogenic.

reproductive toxicity
shall not be classified as a reproductive toxicant.

specific target organ toxicity - single exposure
shall not be classified as a specific target organ toxicant (single exposure).

specific target organ toxicity - repeated exposure
shall not be classified as a specific target organ toxicant (repeated exposure).

aspiration hazard
shall not be classified as presenting an aspiration hazard.

SECTION 12: Ecological information
12.1

toxicity
shall not be classified as hazardous to the aquatic environment.

12.2

persistence and degradability
data are not available.

12.3

bioaccumulative potential
data are not available.

12.4

mobility in soil
data are not available.

12.5

results of PBT and vPvB assessment
data are not available.

12.6

other adverse effects
data are not available.

SECTION 13: Disposal considerations
13.1

waste treatment methods
sewage disposal-relevant information
do not empty into drains. avoid release to the environment. Refer to special instructions/safety data sheets.

waste treatment of containers/packagingscompletely emptied packages can be recycled. handle contaminated packages in the same way as the substance itself.

remarks
please consider the relevant national or regional provisions. waste shall be separated into the categories that can behandled separately by the local or national waste management facilities.

United Kingdom: en

page: 6 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

DNA Isolation Buffer (DIB)
version number: GHS 1.0

date of compilation: 2020-03-26

SECTION 14: Transport information
14.1

UN numbernot subject to transport regulations

14.2

UN proper shipping namenot relevant

14.3

transport hazard class(es)

none

14.4

packing group

not assigned to a packing group

14.5

environmental hazards

non-environmentally hazardous acc. to the dangerous goods regulations

14.6

special precautions for user
there is no additional information.

14.7

transport in bulk according to Annex II of MARPOL and the IBC Codethe cargo is not intended to be carried in bulk.

Information for each of the UN Model Regulationstransport of dangerous goods by road, rail and inland waterway (ADR/RID/ADN)
not subject to ADR, RID and ADN.

International Maritime Dangerous Goods Code (IMDG)
not subject to IMDG.

International Civil Aviation Organization (ICAO-IATA/DGR)
not subject to ICAO-IATA.

SECTION 15: Regulatory information
15.1

safety, health and environmental regulations/legislation specific for the substance or mixture

15.2

Chemical Safety Assessment
chemical safety assessments for substances in this mixture were not carried out.

SECTION 16: Other informationabbreviations and acronyms
abbr.

descriptions of used abbreviations

ADN

Accord européen relatif au transport international des marchandises dangereuses par voies de navigation
intérieures (European Agreement concerning the International Carriage of Dangerous Goods by Inland Waterways)

ADR

Accord européen relatif au transport international des marchandises dangereuses par route (European Agreement concerning the International Carriage of Dangerous Goods by Road)

CLP

Regulation (EC) No 1272/2008 on classification, labelling and packaging of substances and mixtures

DGR

Dangerous Goods Regulations (see IATA/DGR)

GHS"Globally Harmonized System of Classification and Labelling of Chemicals" developed by the United Nations

IATA

International Air Transport Association

IATA/DGR

Dangerous Goods Regulations (DGR) for the air transport (IATA)ICAOInternational Civil Aviation Organization

IMDG

International Maritime Dangerous Goods CodeUnited Kingdom: en

page: 7 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

DNA Isolation Buffer (DIB)
version number: GHS 1.0

date of compilation: 2020-03-26

abbr.

descriptions of used abbreviations

MARPOLInternational Convention for the Prevention of Pollution from Ships (abbr. of "Marine Pollutant")

PBT

Persistent, Bioaccumulative and Toxic

REACH

Registration, Evaluation, Authorisation and Restriction of Chemicals

RID

Règlement concernant le transport International ferroviaire des marchandises Dangereuses (Regulations concerning the International carriage of Dangerous goods by Rail)vPvB

Very Persistent and very Bioaccumulative

key literature references and sources for data
Regulation (EC) No 1272/2008 on classification, labelling and packaging of substances and mixtures. Regulation (EC) No.
1907/2006 (REACH), amended by 2015/830/EU.
transport of dangerous goods by road, rail and inland waterway (ADR/RID/ADN). International Maritime Dangerous Goods
Code (IMDG). Dangerous Goods Regulations (DGR) for the air transport (IATA).

classification procedurephysical and chemical properties: the classification is based on tested mixture.
health hazards, environmental hazards: the method for classification of the mixture is based on ingredients of the mixture(additivity formula).

disclaimer
this information is based upon the present state of our knowledge. this SDS has been compiled and is solely intended for thisproduct.

United Kingdom: en

page: 8 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

proteinase K
version number: GHS 1.0

date of compilation: 2020-03-24

SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1

1.2

product identifiertrade nameproteinase K

registration number (REACH)

not relevant (mixture)

relevant identified uses of the substance or mixture and uses advised against
relevant identified uses

1.3

for research use only, not for use in diagnostic ortherapeutic procedures.

details of the supplier of the safety data sheet
Diagenode SA
LIEGE SCIENCE PARK Rue du Bois Saint-Jean, 34102 Seraing
Belgium
telephone: +32 4 364 20 50
e-mail: info@diagenode.com

1.4

emergency telephone number
emergency information service+32 4 364 20 50
this number is only available during the following office hours: Mon-Fri 09:00 AM - 05:00 PM

poison centre
country

nametelephone

United Kingdom

National Poisons Information Service

111

SECTION 2: Hazards identification
2.1

classification of the substance or mixture
classification according to Regulation (EC) No 1272/2008 (CLP)sectionhazard class

categoryhazard class and category

hazard statement

3.4R

respiratory sensitisation

1

Resp. Sens. 1

H334

for full text of abbreviations: see SECTION 16.

2.2

label elements
labelling according to Regulation (EC) No 1272/2008 (CLP)- signal word

danger- pictograms
GHS08- hazard statements
H334

United Kingdom: en

may cause allergy or asthma symptoms or breathing difficulties if inhaled.

page: 1 / 9

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

proteinase K
version number: GHS 1.0

date of compilation: 2020-03-24- precautionary statements
P261
P284
P304+P340
P342+P311
P501

avoid breathing dust/fume/gas/mist/vapours/spray.
in case of inadequate ventilation wear respiratory protection.
IF INHALED: Remove person to fresh air and keep comfortable for breathing.
if experiencing respiratory symptoms: Call a POISON CENTER/doctor.
dispose of contents/container to industrial combustion plant.

- hazardous ingredients for labelling
2.3

Proteinase, tritirachium album serine

other hazards
results of PBT and vPvB assessment
this mixture does not contain any substances that are assessed to be a PBT or a vPvB.

SECTION 3: Composition/information on ingredients
3.1

substances
not relevant (mixture)

3.2

mixturesdescription of the mixturename of substanceidentifier

wt%classification acc. to GHS

Proteinase, tritirachium album serine

CAS No39450-01-6

2

Skin Irrit. 2 / H315
Eye Irrit. 2 / H319
Resp. Sens. 1A / H334

pictograms

for full text of abbreviations: see SECTION 16.

SECTION 4: First aid measures4.1

description of first aid measuresgeneral notes
do not leave affected person unattended. remove victim out of the danger area. keep affected person warm, still andcovered. take off immediately all contaminated clothing. in all cases of doubt, or when symptoms persist, seek medical advice. in case of unconsciousness place person in the recovery position. Never give anything by mouth.

following inhalation
if breathing is irregular or stopped, immediately seek medical assistance and start first aid actions. provide fresh air.

following skin contact
wash with plenty of soap and water.

following eye contact
remove contact lenses, if present and easy to do. Continue rinsing. irrigate copiously with clean, fresh water for at least 10
minutes, holding the eyelids apart.

following ingestionrinse mouth with water (only if the person is conscious). do NOT induce vomiting.

4.2

most important symptoms and effects, both acute and delayed
symptoms and effects are not known to date.

4.3

indication of any immediate medical attention and special treatment needed
none

United Kingdom: en

page: 2 / 9

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

proteinase K
version number: GHS 1.0

date of compilation: 2020-03-24

SECTION 5: Firefighting measures
5.1

extinguishing media
suitable extinguishing media
water spray, BC-powder, carbon dioxide (CO2)

unsuitable extinguishing media
water jet

5.2

special hazards arising from the substance or mixture

5.3

advice for firefightersin case of fire and/or explosion do not breathe fumes. co-ordinate firefighting measures to the fire surroundings. do not allow firefighting water to enter drains or water courses. collect contaminated firefighting water separately. fight fire withnormal precautions from a reasonable distance.

SECTION 6: Accidental release measures
6.1

personal precautions, protective equipment and emergency procedures
for non-emergency personnel
remove persons to safety.

for emergency responders
wear breathing apparatus if exposed to vapours/dust/spray/gases.

6.2

environmental precautions
keep away from drains, surface and ground water. retain contaminated washing water and dispose of it.

6.3

methods and material for containment and cleaning up
advice on how to contain a spillcovering of drains

advice on how to clean up a spill
wipe up with absorbent material (e.g. cloth, fleece). collect spillage: sawdust, kieselgur (diatomite), sand, universal binder

appropriate containment techniques
use of adsorbent materials.

other information relating to spills and releases
place in appropriate containers for disposal. ventilate affected area.

6.4

reference to other sections
personal protective equipment: see section 8. incompatible materials: see section 10. disposal considerations: see section
13.

SECTION 7: Handling and storage
7.1

precautions for safe handlingrecommendations- measures to prevent fire as well as aerosol and dust generation
use local and general ventilation. use only in well-ventilated areas.

advice on general occupational hygiene
wash hands after use. do not eat, drink and smoke in work areas. remove contaminated clothing and protective equipment
before entering eating areas. never keep food or drink in the vicinity of chemicals. never place chemicals in containers thatare normally used for food or drink. keep away from food, drink and animal feedingstuffs.

United Kingdom: en

page: 3 / 9

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

proteinase K
version number: GHS 1.0

7.2

date of compilation: 2020-03-24

conditions for safe storage, including any incompatibilities
control of effects
protect against external exposure, such as
frost

7.3

specific end use(s)see section 16 for a general overview.

SECTION 8: Exposure controls/personal protection
8.1

control parameters
this information is not available.

8.2

exposure controls
appropriate engineering controls
general ventilation.

individual protection measures (personal protective equipment)eye/face protection
wear eye/face protection.

skin protection- hand protection
wear suitable gloves. chemical protection gloves are suitable, which are tested according to EN 374. check leak-tightness/
impermeability prior to use. in the case of wanting to use the gloves again, clean them before taking off and air them well.
for special purposes, it is recommended to check the resistance to chemicals of the protective gloves mentioned above together with the supplier of these gloves.

- other protection measurestake recovery periods for skin regeneration. preventive skin protection (barrier creams/ointments) is recommended. wash
hands thoroughly after handling.

respiratory protection
in case of inadequate ventilation wear respiratory protection.

environmental exposure controls
use appropriate container to avoid environmental contamination. keep away from drains, surface and ground water.

SECTION 9: Physical and chemical properties
9.1

information on basic physical and chemical properties
appearancephysical stateliquidcolourcolourlessodour

odourless

United Kingdom: en

page: 4 / 9

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

proteinase K
version number: GHS 1.0

date of compilation: 2020-03-24

other safety parameters
pH (value)

not determinedmelting point/freezing point

not determined

initial boiling point and boiling range

not determinedflash point

not determined

evaporation rate

not determined

flammability (solid, gas)

not relevant, (fluid)

explosive limits

not determinedvapour pressure

not determined

density

not determinedvapour density

this information is not available

relative density

information on this property is not available

solubility(ies)not determinedpartition coefficient9.2- n-octanol/water (log KOW)

this information is not available

auto-ignition temperature

not determinedviscosity

not determined

explosive properties

none

oxidising properties

none

other information

there is no additional information

SECTION 10: Stability and reactivity
10.1

reactivity
concerning incompatibility: see below "Conditions to avoid" and "Incompatible materials".

10.2

chemical stability
see below "Conditions to avoid".

10.3

possibility of hazardous reactions
no known hazardous reactions.

10.4

conditions to avoid
there are no specific conditions known which have to be avoided.

10.5

incompatible materials
there is no additional information.

United Kingdom: en

page: 5 / 9

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

proteinase K
version number: GHS 1.0

10.6

date of compilation: 2020-03-24

hazardous decomposition products
reasonably anticipated hazardous decomposition products produced as a result of use, storage, spill and heating are notknown. hazardous combustion products: see section 5.

SECTION 11: Toxicological information
11.1

information on toxicological effects
test data are not available for the complete mixture.

classification procedurethe method for classification of the mixture is based on ingredients of the mixture (additivity formula).

classification according to GHS (1272/2008/EC, CLP)
acute toxicity
shall not be classified as acutely toxic.

skin corrosion/irritation
shall not be classified as corrosive/irritant to skin.

serious eye damage/eye irritation
shall not be classified as seriously damaging to the eye or eye irritant.

respiratory or skin sensitisation
may cause allergy or asthma symptoms or breathing difficulties if inhaled.

germ cell mutagenicity
shall not be classified as germ cell mutagenic.

carcinogenicity
shall not be classified as carcinogenic.

reproductive toxicity
shall not be classified as a reproductive toxicant.

specific target organ toxicity - single exposure
shall not be classified as a specific target organ toxicant (single exposure).

specific target organ toxicity - repeated exposure
shall not be classified as a specific target organ toxicant (repeated exposure).

aspiration hazard
shall not be classified as presenting an aspiration hazard.

SECTION 12: Ecological information
12.1

toxicity
shall not be classified as hazardous to the aquatic environment.

12.2

persistence and degradability
data are not available.

12.3

bioaccumulative potential
data are not available.

12.4

mobility in soil
data are not available.

United Kingdom: en

page: 6 / 9

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

proteinase K
version number: GHS 1.0

12.5

date of compilation: 2020-03-24

results of PBT and vPvB assessment
data are not available.

12.6

other adverse effects
data are not available.

SECTION 13: Disposal considerations
13.1

waste treatment methods
sewage disposal-relevant information
do not empty into drains. avoid release to the environment. Refer to special instructions/safety data sheets.

waste treatment of containers/packagingscompletely emptied packages can be recycled. handle contaminated packages in the same way as the substance itself.

remarks
please consider the relevant national or regional provisions. waste shall be separated into the categories that can behandled separately by the local or national waste management facilities.

SECTION 14: Transport information
14.1

UN numbernot subject to transport regulations

14.2

UN proper shipping namenot relevant

14.3

transport hazard class(es)

none

14.4

packing group

not assigned to a packing group

14.5

environmental hazards

non-environmentally hazardous acc. to the dangerous goods regulations

14.6

special precautions for user
there is no additional information.

14.7

transport in bulk according to Annex II of MARPOL and the IBC Codethe cargo is not intended to be carried in bulk.

Information for each of the UN Model Regulationstransport of dangerous goods by road, rail and inland waterway (ADR/RID/ADN)
not subject to ADR, RID and ADN.

International Maritime Dangerous Goods Code (IMDG)
not subject to IMDG.

International Civil Aviation Organization (ICAO-IATA/DGR)
not subject to ICAO-IATA.

United Kingdom: en

page: 7 / 9

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

proteinase K
version number: GHS 1.0

date of compilation: 2020-03-24

SECTION 15: Regulatory information
15.1

safety, health and environmental regulations/legislation specific for the substance or mixture

15.2

Chemical Safety Assessment
chemical safety assessments for substances in this mixture were not carried out.

SECTION 16: Other informationabbreviations and acronyms
abbr.

descriptions of used abbreviations

ADN

Accord européen relatif au transport international des marchandises dangereuses par voies de navigation
intérieures (European Agreement concerning the International Carriage of Dangerous Goods by Inland Waterways)

ADR

Accord européen relatif au transport international des marchandises dangereuses par route (European Agreement concerning the International Carriage of Dangerous Goods by Road)CAS

Chemical Abstracts Service (service that maintains the most comprehensive list of chemical substances)

CLP

Regulation (EC) No 1272/2008 on classification, labelling and packaging of substances and mixtures

DGR

Dangerous Goods Regulations (see IATA/DGR)

EC No

The EC Inventory (EINECS, ELINCS and the NLP-list) is the source for the seven-digit EC number, an identifierof substances commercially available within the EU (European Union)

EINECS

European Inventory of Existing Commercial Chemical Substances

ELINCS

European List of Notified Chemical Substances

Eye Dam.

Seriously damaging to the eye

Eye Irrit.

Irritant to the eye

GHS"Globally Harmonized System of Classification and Labelling of Chemicals" developed by the United Nations

IATA

International Air Transport Association

IATA/DGR

Dangerous Goods Regulations (DGR) for the air transport (IATA)ICAOInternational Civil Aviation Organization

IMDG

International Maritime Dangerous Goods Codeindex NoThe Index number is the identification code given to the substance in Part 3 of Annex VI to Regulation (EC) No
1272/2008

MARPOLInternational Convention for the Prevention of Pollution from Ships (abbr. of "Marine Pollutant")

NLP

No-Longer Polymer

PBT

Persistent, Bioaccumulative and Toxic

REACH

Registration, Evaluation, Authorisation and Restriction of Chemicals

Resp. Sens.

Respiratory sensitisation

RID

Règlement concernant le transport International ferroviaire des marchandises Dangereuses (Regulations concerning the International carriage of Dangerous goods by Rail)Skin Corr.

Corrosive to skin

Skin Irrit.

Irritant to skinvPvB

Very Persistent and very Bioaccumulative

key literature references and sources for data

United Kingdom: en

page: 8 / 9

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

proteinase K
version number: GHS 1.0

date of compilation: 2020-03-24

Regulation (EC) No 1272/2008 on classification, labelling and packaging of substances and mixtures. Regulation (EC) No.
1907/2006 (REACH), amended by 2015/830/EU.
transport of dangerous goods by road, rail and inland waterway (ADR/RID/ADN). International Maritime Dangerous Goods
Code (IMDG). Dangerous Goods Regulations (DGR) for the air transport (IATA).

classification procedurephysical and chemical properties: the classification is based on tested mixture.
health hazards, environmental hazards: the method for classification of the mixture is based on ingredients of the mixture(additivity formula).

list of relevant phrases (code and full text as stated in chapter 2 and 3)
code

text

H315

Causes skin irritation.

H319

Causes serious eye irritation.

H334

May cause allergy or asthma symptoms or breathing difficulties if inhaled.

disclaimer
this information is based upon the present state of our knowledge. this SDS has been compiled and is solely intended for thisproduct.

United Kingdom: en

page: 9 / 9Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

Primer pair for meDNA spike-in ctrl
version number: GHS 1.0

date of compilation: 2020-04-07

SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1

1.2

product identifiertrade namePrimer pair for meDNA spike-in ctrl

registration number (REACH)

not relevant (mixture)

relevant identified uses of the substance or mixture and uses advised against
relevant identified uses

1.3

for research use only, not for use in diagnostic ortherapeutic procedures.

details of the supplier of the safety data sheet
Diagenode SA
LIEGE SCIENCE PARK Rue du Bois Saint-Jean, 34102 Seraing
Belgium
telephone: +32 4 364 20 50
e-mail: info@diagenode.com

1.4

emergency telephone number
emergency information service+32 4 364 20 50
this number is only available during the following office hours: Mon-Fri 09:00 AM - 05:00 PM

poison centre
country

nametelephone

United Kingdom

National Poisons Information Service

111

SECTION 2: Hazards identification
2.1

classification of the substance or mixture
classification according to Regulation (EC) No 1272/2008 (CLP)
this mixture does not meet the criteria for classification in accordance with Regulation No 1272/2008/EC.

2.2

label elements
labelling according to Regulation (EC) No 1272/2008 (CLP)
not required

2.3

other hazards
results of PBT and vPvB assessment
this mixture does not contain any substances that are assessed to be a PBT or a vPvB.

SECTION 3: Composition/information on ingredients
3.1

substances
not relevant (mixture)

3.2

mixturesdescription of the mixtureThis mixture does not contain any potentially hazardous products.

United Kingdom: en

page: 1 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

Primer pair for meDNA spike-in ctrl
version number: GHS 1.0

date of compilation: 2020-04-07

SECTION 4: First aid measures4.1

description of first aid measuresgeneral notes
do not leave affected person unattended. remove victim out of the danger area. keep affected person warm, still andcovered. take off immediately all contaminated clothing. in all cases of doubt, or when symptoms persist, seek medical advice. in case of unconsciousness place person in the recovery position. Never give anything by mouth.

following inhalation
if breathing is irregular or stopped, immediately seek medical assistance and start first aid actions. provide fresh air.

following skin contact
wash with plenty of soap and water.

following eye contact
remove contact lenses, if present and easy to do. Continue rinsing. irrigate copiously with clean, fresh water for at least 10
minutes, holding the eyelids apart.

following ingestionrinse mouth with water (only if the person is conscious). do NOT induce vomiting.

4.2

most important symptoms and effects, both acute and delayed
symptoms and effects are not known to date.

4.3

indication of any immediate medical attention and special treatment needed
none

SECTION 5: Firefighting measures
5.1

extinguishing media
suitable extinguishing media
water spray, BC-powder, carbon dioxide (CO2)

unsuitable extinguishing media
water jet

5.2

special hazards arising from the substance or mixture
hazardous combustion products
nitrogen oxides (NOx)

5.3

advice for firefightersin case of fire and/or explosion do not breathe fumes. co-ordinate firefighting measures to the fire surroundings. do not allow firefighting water to enter drains or water courses. collect contaminated firefighting water separately. fight fire withnormal precautions from a reasonable distance.

SECTION 6: Accidental release measures
6.1

personal precautions, protective equipment and emergency procedures
for non-emergency personnel
remove persons to safety.

for emergency responders
wear breathing apparatus if exposed to vapours/dust/spray/gases.

6.2

environmental precautions
keep away from drains, surface and ground water. retain contaminated washing water and dispose of it.

United Kingdom: en

page: 2 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

Primer pair for meDNA spike-in ctrl
version number: GHS 1.0

6.3

date of compilation: 2020-04-07

methods and material for containment and cleaning up
advice on how to contain a spillcovering of drains

advice on how to clean up a spill
wipe up with absorbent material (e.g. cloth, fleece). collect spillage: sawdust, kieselgur (diatomite), sand, universal binder

appropriate containment techniques
use of adsorbent materials.

other information relating to spills and releases
place in appropriate containers for disposal. ventilate affected area.

6.4

reference to other sections
hazardous combustion products: see section 5. personal protective equipment: see section 8. incompatible materials: seesection 10. disposal considerations: see section 13.

SECTION 7: Handling and storage
7.1

precautions for safe handlingrecommendations- measures to prevent fire as well as aerosol and dust generation
use local and general ventilation. use only in well-ventilated areas.

advice on general occupational hygiene
wash hands after use. do not eat, drink and smoke in work areas. remove contaminated clothing and protective equipment
before entering eating areas. never keep food or drink in the vicinity of chemicals. never place chemicals in containers thatare normally used for food or drink. keep away from food, drink and animal feedingstuffs.

7.2

conditions for safe storage, including any incompatibilities
control of effects
protect against external exposure, such as
frost

7.3

specific end use(s)see section 16 for a general overview.

SECTION 8: Exposure controls/personal protection
8.1

control parameters
this information is not available.

8.2

exposure controls
appropriate engineering controls
general ventilation.

individual protection measures (personal protective equipment)eye/face protection
wear eye/face protection.

United Kingdom: en

page: 3 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

Primer pair for meDNA spike-in ctrl
version number: GHS 1.0

date of compilation: 2020-04-07

skin protection- hand protection
wear suitable gloves. chemical protection gloves are suitable, which are tested according to EN 374. check leak-tightness/
impermeability prior to use. in the case of wanting to use the gloves again, clean them before taking off and air them well.
for special purposes, it is recommended to check the resistance to chemicals of the protective gloves mentioned above together with the supplier of these gloves.

- other protection measurestake recovery periods for skin regeneration. preventive skin protection (barrier creams/ointments) is recommended. wash
hands thoroughly after handling.

respiratory protection
in case of inadequate ventilation wear respiratory protection.

environmental exposure controls
use appropriate container to avoid environmental contamination. keep away from drains, surface and ground water.

SECTION 9: Physical and chemical properties
9.1

information on basic physical and chemical properties
appearancephysical stateliquidcolourcolourlessodour

odourlessother safety parameters
pH (value)

not determinedmelting point/freezing point

not determined

initial boiling point and boiling range

not determinedflash point

not determined

evaporation rate

not determined

flammability (solid, gas)

not relevant, (fluid)

explosive limits

not determinedvapour pressure

not determined

density

not determinedvapour density

this information is not available

relative density

information on this property is not available

solubility(ies)not determinedpartition coefficient- n-octanol/water (log KOW)
United Kingdom: enthis information is not available
page: 4 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

Primer pair for meDNA spike-in ctrl
version number: GHS 1.0

9.2

date of compilation: 2020-04-07

auto-ignition temperature

not determinedviscosity

not determined

explosive properties

none

oxidising properties

none

other information

there is no additional information

SECTION 10: Stability and reactivity
10.1

reactivity
concerning incompatibility: see below "Conditions to avoid" and "Incompatible materials".

10.2

chemical stability
the material is stable under normal ambient and anticipated storage and handling conditions of temperature and pressure.

10.3

possibility of hazardous reactions
no known hazardous reactions.

10.4

conditions to avoid
there are no specific conditions known which have to be avoided.

10.5

incompatible materials
there is no additional information.

10.6

hazardous decomposition products
reasonably anticipated hazardous decomposition products produced as a result of use, storage, spill and heating are notknown. hazardous combustion products: see section 5.

SECTION 11: Toxicological information
11.1

information on toxicological effects
test data are not available for the complete mixture.

classification procedurethe method for classification of the mixture is based on ingredients of the mixture (additivity formula).

classification according to GHS (1272/2008/EC, CLP)
this mixture does not meet the criteria for classification in accordance with Regulation No 1272/2008/EC.

acute toxicity
shall not be classified as acutely toxic.

skin corrosion/irritation
shall not be classified as corrosive/irritant to skin.

serious eye damage/eye irritation
shall not be classified as seriously damaging to the eye or eye irritant.

respiratory or skin sensitisation
shall not be classified as a respiratory or skin sensitiser.

germ cell mutagenicity
shall not be classified as germ cell mutagenic.

United Kingdom: en

page: 5 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

Primer pair for meDNA spike-in ctrl
version number: GHS 1.0

date of compilation: 2020-04-07

carcinogenicity
shall not be classified as carcinogenic.

reproductive toxicity
shall not be classified as a reproductive toxicant.

specific target organ toxicity - single exposure
shall not be classified as a specific target organ toxicant (single exposure).

specific target organ toxicity - repeated exposure
shall not be classified as a specific target organ toxicant (repeated exposure).

aspiration hazard
shall not be classified as presenting an aspiration hazard.

SECTION 12: Ecological information
12.1

toxicity
shall not be classified as hazardous to the aquatic environment.

12.2

persistence and degradability
data are not available.

12.3

bioaccumulative potential
data are not available.

12.4

mobility in soil
data are not available.

12.5

results of PBT and vPvB assessment
data are not available.

12.6

other adverse effects
data are not available.

SECTION 13: Disposal considerations
13.1

waste treatment methods
sewage disposal-relevant information
do not empty into drains. avoid release to the environment. Refer to special instructions/safety data sheets.

waste treatment of containers/packagingscompletely emptied packages can be recycled. handle contaminated packages in the same way as the substance itself.

remarks
please consider the relevant national or regional provisions. waste shall be separated into the categories that can behandled separately by the local or national waste management facilities.

United Kingdom: en

page: 6 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

Primer pair for meDNA spike-in ctrl
version number: GHS 1.0

date of compilation: 2020-04-07

SECTION 14: Transport information
14.1

UN numbernot subject to transport regulations

14.2

UN proper shipping namenot relevant

14.3

transport hazard class(es)

none

14.4

packing group

not assigned to a packing group

14.5

environmental hazards

non-environmentally hazardous acc. to the dangerous goods regulations

14.6

special precautions for user
there is no additional information.

14.7

transport in bulk according to Annex II of MARPOL and the IBC Codethe cargo is not intended to be carried in bulk.

Information for each of the UN Model Regulationstransport of dangerous goods by road, rail and inland waterway (ADR/RID/ADN)
not subject to ADR, RID and ADN.

International Maritime Dangerous Goods Code (IMDG)
not subject to IMDG.

International Civil Aviation Organization (ICAO-IATA/DGR)
not subject to ICAO-IATA.

SECTION 15: Regulatory information
15.1

safety, health and environmental regulations/legislation specific for the substance or mixture

15.2

Chemical Safety Assessment
chemical safety assessments for substances in this mixture were not carried out.

SECTION 16: Other informationabbreviations and acronyms
abbr.

descriptions of used abbreviations

ADN

Accord européen relatif au transport international des marchandises dangereuses par voies de navigation
intérieures (European Agreement concerning the International Carriage of Dangerous Goods by Inland Waterways)

ADR

Accord européen relatif au transport international des marchandises dangereuses par route (European Agreement concerning the International Carriage of Dangerous Goods by Road)

CLP

Regulation (EC) No 1272/2008 on classification, labelling and packaging of substances and mixtures

DGR

Dangerous Goods Regulations (see IATA/DGR)

GHS"Globally Harmonized System of Classification and Labelling of Chemicals" developed by the United Nations

IATA

International Air Transport Association

IATA/DGR

Dangerous Goods Regulations (DGR) for the air transport (IATA)ICAOInternational Civil Aviation Organization

IMDG

International Maritime Dangerous Goods CodeUnited Kingdom: en

page: 7 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

Primer pair for meDNA spike-in ctrl
version number: GHS 1.0

date of compilation: 2020-04-07

abbr.

descriptions of used abbreviations

MARPOLInternational Convention for the Prevention of Pollution from Ships (abbr. of "Marine Pollutant")

PBT

Persistent, Bioaccumulative and Toxic

REACH

Registration, Evaluation, Authorisation and Restriction of Chemicals

RID

Règlement concernant le transport International ferroviaire des marchandises Dangereuses (Regulations concerning the International carriage of Dangerous goods by Rail)vPvB

Very Persistent and very Bioaccumulative

key literature references and sources for data
Regulation (EC) No 1272/2008 on classification, labelling and packaging of substances and mixtures. Regulation (EC) No.
1907/2006 (REACH), amended by 2015/830/EU.
transport of dangerous goods by road, rail and inland waterway (ADR/RID/ADN). International Maritime Dangerous Goods
Code (IMDG). Dangerous Goods Regulations (DGR) for the air transport (IATA).

classification procedurephysical and chemical properties: the classification is based on tested mixture.
health hazards, environmental hazards: the method for classification of the mixture is based on ingredients of the mixture(additivity formula).

disclaimer
this information is based upon the present state of our knowledge. this SDS has been compiled and is solely intended for thisproduct.

United Kingdom: en

page: 8 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

Primer pair for unDNA spike-in ctrl
version number: GHS 1.0

date of compilation: 2020-04-07

SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1

1.2

product identifiertrade namePrimer pair for unDNA spike-in ctrl

registration number (REACH)

not relevant (mixture)

relevant identified uses of the substance or mixture and uses advised against
relevant identified uses

1.3

for research use only, not for use in diagnostic ortherapeutic procedures.

details of the supplier of the safety data sheet
Diagenode SA
LIEGE SCIENCE PARK Rue du Bois Saint-Jean, 34102 Seraing
Belgium
telephone: +32 4 364 20 50
e-mail: info@diagenode.com

1.4

emergency telephone number
emergency information service+32 4 364 20 50
this number is only available during the following office hours: Mon-Fri 09:00 AM - 05:00 PM

poison centre
country

nametelephone

United Kingdom

National Poisons Information Service

111

SECTION 2: Hazards identification
2.1

classification of the substance or mixture
classification according to Regulation (EC) No 1272/2008 (CLP)
this mixture does not meet the criteria for classification in accordance with Regulation No 1272/2008/EC.

2.2

label elements
labelling according to Regulation (EC) No 1272/2008 (CLP)
not required

2.3

other hazards
results of PBT and vPvB assessment
this mixture does not contain any substances that are assessed to be a PBT or a vPvB.

SECTION 3: Composition/information on ingredients
3.1

substances
not relevant (mixture)

3.2

mixturesdescription of the mixtureThis mixture does not contain any potentially hazardous products.

United Kingdom: en

page: 1 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

Primer pair for unDNA spike-in ctrl
version number: GHS 1.0

date of compilation: 2020-04-07

SECTION 4: First aid measures4.1

description of first aid measuresgeneral notes
do not leave affected person unattended. remove victim out of the danger area. keep affected person warm, still andcovered. take off immediately all contaminated clothing. in all cases of doubt, or when symptoms persist, seek medical advice. in case of unconsciousness place person in the recovery position. Never give anything by mouth.

following inhalation
if breathing is irregular or stopped, immediately seek medical assistance and start first aid actions. provide fresh air.

following skin contact
wash with plenty of soap and water.

following eye contact
remove contact lenses, if present and easy to do. Continue rinsing. irrigate copiously with clean, fresh water for at least 10
minutes, holding the eyelids apart.

following ingestionrinse mouth with water (only if the person is conscious). do NOT induce vomiting.

4.2

most important symptoms and effects, both acute and delayed
symptoms and effects are not known to date.

4.3

indication of any immediate medical attention and special treatment needed
none

SECTION 5: Firefighting measures
5.1

extinguishing media
suitable extinguishing media
water spray, BC-powder, carbon dioxide (CO2)

unsuitable extinguishing media
water jet

5.2

special hazards arising from the substance or mixture
hazardous combustion products
nitrogen oxides (NOx)

5.3

advice for firefightersin case of fire and/or explosion do not breathe fumes. co-ordinate firefighting measures to the fire surroundings. do not allow firefighting water to enter drains or water courses. collect contaminated firefighting water separately. fight fire withnormal precautions from a reasonable distance.

SECTION 6: Accidental release measures
6.1

personal precautions, protective equipment and emergency procedures
for non-emergency personnel
remove persons to safety.

for emergency responders
wear breathing apparatus if exposed to vapours/dust/spray/gases.

6.2

environmental precautions
keep away from drains, surface and ground water. retain contaminated washing water and dispose of it.

United Kingdom: en

page: 2 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

Primer pair for unDNA spike-in ctrl
version number: GHS 1.0

6.3

date of compilation: 2020-04-07

methods and material for containment and cleaning up
advice on how to contain a spillcovering of drains

advice on how to clean up a spill
wipe up with absorbent material (e.g. cloth, fleece). collect spillage: sawdust, kieselgur (diatomite), sand, universal binder

appropriate containment techniques
use of adsorbent materials.

other information relating to spills and releases
place in appropriate containers for disposal. ventilate affected area.

6.4

reference to other sections
hazardous combustion products: see section 5. personal protective equipment: see section 8. incompatible materials: seesection 10. disposal considerations: see section 13.

SECTION 7: Handling and storage
7.1

precautions for safe handlingrecommendations- measures to prevent fire as well as aerosol and dust generation
use local and general ventilation. use only in well-ventilated areas.

advice on general occupational hygiene
wash hands after use. do not eat, drink and smoke in work areas. remove contaminated clothing and protective equipment
before entering eating areas. never keep food or drink in the vicinity of chemicals. never place chemicals in containers thatare normally used for food or drink. keep away from food, drink and animal feedingstuffs.

7.2

conditions for safe storage, including any incompatibilities
control of effects
protect against external exposure, such as
frost

7.3

specific end use(s)see section 16 for a general overview.

SECTION 8: Exposure controls/personal protection
8.1

control parameters
this information is not available.

8.2

exposure controls
appropriate engineering controls
general ventilation.

individual protection measures (personal protective equipment)eye/face protection
wear eye/face protection.

United Kingdom: en

page: 3 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

Primer pair for unDNA spike-in ctrl
version number: GHS 1.0

date of compilation: 2020-04-07

skin protection- hand protection
wear suitable gloves. chemical protection gloves are suitable, which are tested according to EN 374. check leak-tightness/
impermeability prior to use. in the case of wanting to use the gloves again, clean them before taking off and air them well.
for special purposes, it is recommended to check the resistance to chemicals of the protective gloves mentioned above together with the supplier of these gloves.

- other protection measurestake recovery periods for skin regeneration. preventive skin protection (barrier creams/ointments) is recommended. wash
hands thoroughly after handling.

respiratory protection
in case of inadequate ventilation wear respiratory protection.

environmental exposure controls
use appropriate container to avoid environmental contamination. keep away from drains, surface and ground water.

SECTION 9: Physical and chemical properties
9.1

information on basic physical and chemical properties
appearancephysical stateliquidcolourcolourlessodour

odourlessother safety parameters
pH (value)

not determinedmelting point/freezing point

not determined

initial boiling point and boiling range

not determinedflash point

not determined

evaporation rate

not determined

flammability (solid, gas)

not relevant, (fluid)

explosive limits

not determinedvapour pressure

not determined

density

not determinedvapour density

this information is not available

relative density

information on this property is not available

solubility(ies)not determinedpartition coefficient- n-octanol/water (log KOW)
United Kingdom: enthis information is not available
page: 4 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

Primer pair for unDNA spike-in ctrl
version number: GHS 1.0

9.2

date of compilation: 2020-04-07

auto-ignition temperature

not determinedviscosity

not determined

explosive properties

none

oxidising properties

none

other information

there is no additional information

SECTION 10: Stability and reactivity
10.1

reactivity
concerning incompatibility: see below "Conditions to avoid" and "Incompatible materials".

10.2

chemical stability
the material is stable under normal ambient and anticipated storage and handling conditions of temperature and pressure.

10.3

possibility of hazardous reactions
no known hazardous reactions.

10.4

conditions to avoid
there are no specific conditions known which have to be avoided.

10.5

incompatible materials
there is no additional information.

10.6

hazardous decomposition products
reasonably anticipated hazardous decomposition products produced as a result of use, storage, spill and heating are notknown. hazardous combustion products: see section 5.

SECTION 11: Toxicological information
11.1

information on toxicological effects
test data are not available for the complete mixture.

classification procedurethe method for classification of the mixture is based on ingredients of the mixture (additivity formula).

classification according to GHS (1272/2008/EC, CLP)
this mixture does not meet the criteria for classification in accordance with Regulation No 1272/2008/EC.

acute toxicity
shall not be classified as acutely toxic.

skin corrosion/irritation
shall not be classified as corrosive/irritant to skin.

serious eye damage/eye irritation
shall not be classified as seriously damaging to the eye or eye irritant.

respiratory or skin sensitisation
shall not be classified as a respiratory or skin sensitiser.

germ cell mutagenicity
shall not be classified as germ cell mutagenic.

United Kingdom: en

page: 5 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

Primer pair for unDNA spike-in ctrl
version number: GHS 1.0

date of compilation: 2020-04-07

carcinogenicity
shall not be classified as carcinogenic.

reproductive toxicity
shall not be classified as a reproductive toxicant.

specific target organ toxicity - single exposure
shall not be classified as a specific target organ toxicant (single exposure).

specific target organ toxicity - repeated exposure
shall not be classified as a specific target organ toxicant (repeated exposure).

aspiration hazard
shall not be classified as presenting an aspiration hazard.

SECTION 12: Ecological information
12.1

toxicity
shall not be classified as hazardous to the aquatic environment.

12.2

persistence and degradability
data are not available.

12.3

bioaccumulative potential
data are not available.

12.4

mobility in soil
data are not available.

12.5

results of PBT and vPvB assessment
data are not available.

12.6

other adverse effects
data are not available.

SECTION 13: Disposal considerations
13.1

waste treatment methods
sewage disposal-relevant information
do not empty into drains. avoid release to the environment. Refer to special instructions/safety data sheets.

waste treatment of containers/packagingscompletely emptied packages can be recycled. handle contaminated packages in the same way as the substance itself.

remarks
please consider the relevant national or regional provisions. waste shall be separated into the categories that can behandled separately by the local or national waste management facilities.

United Kingdom: en

page: 6 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

Primer pair for unDNA spike-in ctrl
version number: GHS 1.0

date of compilation: 2020-04-07

SECTION 14: Transport information
14.1

UN numbernot subject to transport regulations

14.2

UN proper shipping namenot relevant

14.3

transport hazard class(es)

none

14.4

packing group

not assigned to a packing group

14.5

environmental hazards

non-environmentally hazardous acc. to the dangerous goods regulations

14.6

special precautions for user
there is no additional information.

14.7

transport in bulk according to Annex II of MARPOL and the IBC Codethe cargo is not intended to be carried in bulk.

Information for each of the UN Model Regulationstransport of dangerous goods by road, rail and inland waterway (ADR/RID/ADN)
not subject to ADR, RID and ADN.

International Maritime Dangerous Goods Code (IMDG)
not subject to IMDG.

International Civil Aviation Organization (ICAO-IATA/DGR)
not subject to ICAO-IATA.

SECTION 15: Regulatory information
15.1

safety, health and environmental regulations/legislation specific for the substance or mixture

15.2

Chemical Safety Assessment
chemical safety assessments for substances in this mixture were not carried out.

SECTION 16: Other informationabbreviations and acronyms
abbr.

descriptions of used abbreviations

ADN

Accord européen relatif au transport international des marchandises dangereuses par voies de navigation
intérieures (European Agreement concerning the International Carriage of Dangerous Goods by Inland Waterways)

ADR

Accord européen relatif au transport international des marchandises dangereuses par route (European Agreement concerning the International Carriage of Dangerous Goods by Road)

CLP

Regulation (EC) No 1272/2008 on classification, labelling and packaging of substances and mixtures

DGR

Dangerous Goods Regulations (see IATA/DGR)

GHS"Globally Harmonized System of Classification and Labelling of Chemicals" developed by the United Nations

IATA

International Air Transport Association

IATA/DGR

Dangerous Goods Regulations (DGR) for the air transport (IATA)ICAOInternational Civil Aviation Organization

IMDG

International Maritime Dangerous Goods CodeUnited Kingdom: en

page: 7 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

Primer pair for unDNA spike-in ctrl
version number: GHS 1.0

date of compilation: 2020-04-07

abbr.

descriptions of used abbreviations

MARPOLInternational Convention for the Prevention of Pollution from Ships (abbr. of "Marine Pollutant")

PBT

Persistent, Bioaccumulative and Toxic

REACH

Registration, Evaluation, Authorisation and Restriction of Chemicals

RID

Règlement concernant le transport International ferroviaire des marchandises Dangereuses (Regulations concerning the International carriage of Dangerous goods by Rail)vPvB

Very Persistent and very Bioaccumulative

key literature references and sources for data
Regulation (EC) No 1272/2008 on classification, labelling and packaging of substances and mixtures. Regulation (EC) No.
1907/2006 (REACH), amended by 2015/830/EU.
transport of dangerous goods by road, rail and inland waterway (ADR/RID/ADN). International Maritime Dangerous Goods
Code (IMDG). Dangerous Goods Regulations (DGR) for the air transport (IATA).

classification procedurephysical and chemical properties: the classification is based on tested mixture.
health hazards, environmental hazards: the method for classification of the mixture is based on ingredients of the mixture(additivity formula).

disclaimer
this information is based upon the present state of our knowledge. this SDS has been compiled and is solely intended for thisproduct.

United Kingdom: en

page: 8 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

TSH2B primer pairversion number: GHS 1.0

date of compilation: 2020-03-24

SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1

1.2

product identifiertrade name

TSH2B primer pairregistration number (REACH)

not relevant (mixture)

product code(s)C17011041

relevant identified uses of the substance or mixture and uses advised against
relevant identified uses

1.3

for research use only, not for use in diagnostic ortherapeutic procedures.

details of the supplier of the safety data sheet
Diagenode SA
LIEGE SCIENCE PARK Rue du Bois Saint-Jean, 34102 Seraing
Belgium
telephone: +32 4 364 20 50
e-mail: info@diagenode.com

1.4

emergency telephone number
emergency information service+32 4 364 20 50
this number is only available during the following office hours: Mon-Fri 09:00 AM - 05:00 PM

poison centre
country

nametelephone

United Kingdom

National Poisons Information Service

111

SECTION 2: Hazards identification
2.1

classification of the substance or mixture
classification according to Regulation (EC) No 1272/2008 (CLP)
this mixture does not meet the criteria for classification in accordance with Regulation No 1272/2008/EC.

2.2

label elements
labelling according to Regulation (EC) No 1272/2008 (CLP)
not required

2.3

other hazards
results of PBT and vPvB assessment
this mixture does not contain any substances that are assessed to be a PBT or a vPvB.

United Kingdom: en

page: 1 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

TSH2B primer pairversion number: GHS 1.0

date of compilation: 2020-03-24

SECTION 3: Composition/information on ingredients
3.1

substances
not relevant (mixture)

3.2

mixturesdescription of the mixtureThis product is composed of synthetic DNA oligonucleotides in an aqueous buffer solution. It does not contain any hazardous
ingredients.

SECTION 4: First aid measures4.1

description of first aid measuresgeneral notes
do not leave affected person unattended. remove victim out of the danger area. keep affected person warm, still andcovered. take off immediately all contaminated clothing. in all cases of doubt, or when symptoms persist, seek medical advice. in case of unconsciousness place person in the recovery position. Never give anything by mouth.

following inhalation
if breathing is irregular or stopped, immediately seek medical assistance and start first aid actions. provide fresh air.

following skin contact
wash with plenty of soap and water.

following eye contact
remove contact lenses, if present and easy to do. Continue rinsing. irrigate copiously with clean, fresh water for at least 10
minutes, holding the eyelids apart.

following ingestionrinse mouth with water (only if the person is conscious). do NOT induce vomiting.

4.2

most important symptoms and effects, both acute and delayed
symptoms and effects are not known to date.

4.3

indication of any immediate medical attention and special treatment needed
none

SECTION 5: Firefighting measures
5.1

extinguishing media
suitable extinguishing media
water spray, BC-powder, carbon dioxide (CO2)

unsuitable extinguishing media
water jet

5.2

special hazards arising from the substance or mixture

5.3

advice for firefightersin case of fire and/or explosion do not breathe fumes. co-ordinate firefighting measures to the fire surroundings. do not allow firefighting water to enter drains or water courses. collect contaminated firefighting water separately. fight fire withnormal precautions from a reasonable distance.

United Kingdom: en

page: 2 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

TSH2B primer pairversion number: GHS 1.0

date of compilation: 2020-03-24

SECTION 6: Accidental release measures
6.1

personal precautions, protective equipment and emergency procedures
for non-emergency personnel
remove persons to safety.

for emergency responders
wear breathing apparatus if exposed to vapours/dust/spray/gases.

6.2

environmental precautions
keep away from drains, surface and ground water. retain contaminated washing water and dispose of it.

6.3

methods and material for containment and cleaning up
advice on how to contain a spillcovering of drains

advice on how to clean up a spill
wipe up with absorbent material (e.g. cloth, fleece). collect spillage: sawdust, kieselgur (diatomite), sand, universal binder

appropriate containment techniques
use of adsorbent materials.

other information relating to spills and releases
place in appropriate containers for disposal. ventilate affected area.

6.4

reference to other sections
personal protective equipment: see section 8. incompatible materials: see section 10. disposal considerations: see section
13.

SECTION 7: Handling and storage
7.1

precautions for safe handlingrecommendations- measures to prevent fire as well as aerosol and dust generation
use local and general ventilation. use only in well-ventilated areas.

advice on general occupational hygiene
wash hands after use. do not eat, drink and smoke in work areas. remove contaminated clothing and protective equipment
before entering eating areas. never keep food or drink in the vicinity of chemicals. never place chemicals in containers thatare normally used for food or drink. keep away from food, drink and animal feedingstuffs.

7.2

conditions for safe storage, including any incompatibilities
control of effects
protect against external exposure, such as
frost

7.3

specific end use(s)see section 16 for a general overview.

United Kingdom: en

page: 3 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

TSH2B primer pairversion number: GHS 1.0

date of compilation: 2020-03-24

SECTION 8: Exposure controls/personal protection
8.1

control parameters
this information is not available.

8.2

exposure controls
appropriate engineering controls
general ventilation.

individual protection measures (personal protective equipment)eye/face protection
wear eye/face protection.

skin protection- hand protection
wear suitable gloves. chemical protection gloves are suitable, which are tested according to EN 374. check leak-tightness/
impermeability prior to use. in the case of wanting to use the gloves again, clean them before taking off and air them well.
for special purposes, it is recommended to check the resistance to chemicals of the protective gloves mentioned above together with the supplier of these gloves.

- other protection measurestake recovery periods for skin regeneration. preventive skin protection (barrier creams/ointments) is recommended. wash
hands thoroughly after handling.

respiratory protection
in case of inadequate ventilation wear respiratory protection.

environmental exposure controls
use appropriate container to avoid environmental contamination. keep away from drains, surface and ground water.

SECTION 9: Physical and chemical properties
9.1

information on basic physical and chemical properties
appearancephysical stateliquidcolourcolourlessodour

odourlessother safety parameters
pH (value)

not determinedmelting point/freezing point

not determined

initial boiling point and boiling range

not determinedflash point

not determined

evaporation rate

not determined

flammability (solid, gas)

not relevant, (fluid)

explosive limits

not determined

United Kingdom: en

page: 4 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

TSH2B primer pairversion number: GHS 1.0

date of compilation: 2020-03-24

vapour pressure

not determined

density

not determinedvapour density

this information is not available

relative density

information on this property is not available

solubility(ies)not determinedpartition coefficient9.2- n-octanol/water (log KOW)

this information is not available

auto-ignition temperature

not determinedviscosity

not determined

explosive properties

none

oxidising properties

none

other information

there is no additional information

SECTION 10: Stability and reactivity
10.1

reactivity
concerning incompatibility: see below "Conditions to avoid" and "Incompatible materials".

10.2

chemical stability
the material is stable under normal ambient and anticipated storage and handling conditions of temperature and pressure.

10.3

possibility of hazardous reactions
no known hazardous reactions.

10.4

conditions to avoid
there are no specific conditions known which have to be avoided.

10.5

incompatible materials
there is no additional information.

10.6

hazardous decomposition products
reasonably anticipated hazardous decomposition products produced as a result of use, storage, spill and heating are notknown. hazardous combustion products: see section 5.

SECTION 11: Toxicological information
11.1

information on toxicological effects
test data are not available for the complete mixture.

classification procedurethe method for classification of the mixture is based on ingredients of the mixture (additivity formula).

classification according to GHS (1272/2008/EC, CLP)
this mixture does not meet the criteria for classification in accordance with Regulation No 1272/2008/EC.

United Kingdom: en

page: 5 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

TSH2B primer pairversion number: GHS 1.0

date of compilation: 2020-03-24

acute toxicity
shall not be classified as acutely toxic.

skin corrosion/irritation
shall not be classified as corrosive/irritant to skin.

serious eye damage/eye irritation
shall not be classified as seriously damaging to the eye or eye irritant.

respiratory or skin sensitisation
shall not be classified as a respiratory or skin sensitiser.

germ cell mutagenicity
shall not be classified as germ cell mutagenic.

carcinogenicity
shall not be classified as carcinogenic.

reproductive toxicity
shall not be classified as a reproductive toxicant.

specific target organ toxicity - single exposure
shall not be classified as a specific target organ toxicant (single exposure).

specific target organ toxicity - repeated exposure
shall not be classified as a specific target organ toxicant (repeated exposure).

aspiration hazard
shall not be classified as presenting an aspiration hazard.

SECTION 12: Ecological information
12.1

toxicity
shall not be classified as hazardous to the aquatic environment.

12.2

persistence and degradability
data are not available.

12.3

bioaccumulative potential
data are not available.

12.4

mobility in soil
data are not available.

12.5

results of PBT and vPvB assessment
data are not available.

12.6

other adverse effects
data are not available.

United Kingdom: en

page: 6 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

TSH2B primer pairversion number: GHS 1.0

date of compilation: 2020-03-24

SECTION 13: Disposal considerations
13.1

waste treatment methods
sewage disposal-relevant information
do not empty into drains. avoid release to the environment. Refer to special instructions/safety data sheets.

waste treatment of containers/packagingscompletely emptied packages can be recycled. handle contaminated packages in the same way as the substance itself.

remarks
please consider the relevant national or regional provisions. waste shall be separated into the categories that can behandled separately by the local or national waste management facilities.

SECTION 14: Transport information
14.1

UN numbernot subject to transport regulations

14.2

UN proper shipping namenot relevant

14.3

transport hazard class(es)

none

14.4

packing group

not assigned to a packing group

14.5

environmental hazards

non-environmentally hazardous acc. to the dangerous goods regulations

14.6

special precautions for user
there is no additional information.

14.7

transport in bulk according to Annex II of MARPOL and the IBC Codethe cargo is not intended to be carried in bulk.

Information for each of the UN Model Regulationstransport of dangerous goods by road, rail and inland waterway (ADR/RID/ADN)
not subject to ADR, RID and ADN.

International Maritime Dangerous Goods Code (IMDG)
not subject to IMDG.

International Civil Aviation Organization (ICAO-IATA/DGR)
not subject to ICAO-IATA.

SECTION 15: Regulatory information
15.1

safety, health and environmental regulations/legislation specific for the substance or mixture

15.2

Chemical Safety Assessment
chemical safety assessments for substances in this mixture were not carried out.

United Kingdom: en

page: 7 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

TSH2B primer pairversion number: GHS 1.0

date of compilation: 2020-03-24

SECTION 16: Other informationabbreviations and acronyms
abbr.

descriptions of used abbreviations

ADN

Accord européen relatif au transport international des marchandises dangereuses par voies de navigation
intérieures (European Agreement concerning the International Carriage of Dangerous Goods by Inland Waterways)

ADR

Accord européen relatif au transport international des marchandises dangereuses par route (European Agreement concerning the International Carriage of Dangerous Goods by Road)

CLP

Regulation (EC) No 1272/2008 on classification, labelling and packaging of substances and mixtures

DGR

Dangerous Goods Regulations (see IATA/DGR)

GHS"Globally Harmonized System of Classification and Labelling of Chemicals" developed by the United Nations

IATA

International Air Transport Association

IATA/DGR

Dangerous Goods Regulations (DGR) for the air transport (IATA)ICAOInternational Civil Aviation Organization

IMDG

International Maritime Dangerous Goods CodeMARPOLInternational Convention for the Prevention of Pollution from Ships (abbr. of "Marine Pollutant")

PBT

Persistent, Bioaccumulative and Toxic

REACH

Registration, Evaluation, Authorisation and Restriction of Chemicals

RID

Règlement concernant le transport International ferroviaire des marchandises Dangereuses (Regulations concerning the International carriage of Dangerous goods by Rail)vPvB

Very Persistent and very Bioaccumulative

key literature references and sources for data
Regulation (EC) No 1272/2008 on classification, labelling and packaging of substances and mixtures. Regulation (EC) No.
1907/2006 (REACH), amended by 2015/830/EU.
transport of dangerous goods by road, rail and inland waterway (ADR/RID/ADN). International Maritime Dangerous Goods
Code (IMDG). Dangerous Goods Regulations (DGR) for the air transport (IATA).

classification procedurephysical and chemical properties: the classification is based on tested mixture.
health hazards, environmental hazards: the method for classification of the mixture is based on ingredients of the mixture(additivity formula).

disclaimer
this information is based upon the present state of our knowledge. this SDS has been compiled and is solely intended for thisproduct.

United Kingdom: en

page: 8 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

ChIP-seq grade GAPDH TSS primer pairversion number: GHS 3.0
replaces version of: 2019-12-12 (GHS 2)

revision: 2019-12-12

SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1

1.2

product identifiertrade name

ChIP-seq grade GAPDH TSS primer pairregistration number (REACH)

not relevant (mixture)

product code(s)C17011047

relevant identified uses of the substance or mixture and uses advised against
relevant identified uses

1.3

for research use only, not for use in diagnostic ortherapeutic procedures.

details of the supplier of the safety data sheet
Diagenode SA
LIEGE SCIENCE PARK Rue du Bois Saint-Jean, 34102 Seraing
Belgium
telephone: +32 4 364 20 50
e-mail: info@diagenode.com

1.4

emergency telephone number
emergency information service+32 4 364 20 50
this number is only available during the following office hours: Mon-Fri 09:00 AM - 05:00 PM

poison centre
country

nametelephone

United Kingdom

National Poisons Information Service

111

SECTION 2: Hazards identification
2.1

classification of the substance or mixture
classification according to Regulation (EC) No 1272/2008 (CLP)
this mixture does not meet the criteria for classification in accordance with Regulation No 1272/2008/EC.

2.2

label elements
labelling according to Regulation (EC) No 1272/2008 (CLP)
not required

2.3

other hazards
results of PBT and vPvB assessment
this mixture does not contain any substances that are assessed to be a PBT or a vPvB.

United Kingdom: en

page: 1 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

ChIP-seq grade GAPDH TSS primer pairversion number: GHS 3.0
replaces version of: 2019-12-12 (GHS 2)

revision: 2019-12-12

SECTION 3: Composition/information on ingredients
3.1

substances
not relevant (mixture)

3.2

mixturesdescription of the mixtureThis product is composed of synthetic DNA oligonucleotides in an aqueous buffer solution. It does not contain any hazardous
ingredients. This mixture does not contain any potentially hazardous products.

SECTION 4: First aid measures4.1

description of first aid measuresgeneral notes
do not leave affected person unattended. remove victim out of the danger area. keep affected person warm, still andcovered. take off immediately all contaminated clothing. in all cases of doubt, or when symptoms persist, seek medical advice. in case of unconsciousness place person in the recovery position. Never give anything by mouth.

following inhalation
if breathing is irregular or stopped, immediately seek medical assistance and start first aid actions. provide fresh air.

following skin contact
wash with plenty of soap and water.

following eye contact
remove contact lenses, if present and easy to do. Continue rinsing. irrigate copiously with clean, fresh water for at least 10
minutes, holding the eyelids apart.

following ingestionrinse mouth with water (only if the person is conscious). do NOT induce vomiting.

4.2

most important symptoms and effects, both acute and delayed
symptoms and effects are not known to date.

4.3

indication of any immediate medical attention and special treatment needed
none

SECTION 5: Firefighting measures
5.1

extinguishing media
suitable extinguishing media
water spray, BC-powder, carbon dioxide (CO2)

unsuitable extinguishing media
water jet

5.2

special hazards arising from the substance or mixture

5.3

advice for firefightersin case of fire and/or explosion do not breathe fumes. co-ordinate firefighting measures to the fire surroundings. do not allow firefighting water to enter drains or water courses. collect contaminated firefighting water separately. fight fire withnormal precautions from a reasonable distance.

United Kingdom: en

page: 2 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

ChIP-seq grade GAPDH TSS primer pairversion number: GHS 3.0
replaces version of: 2019-12-12 (GHS 2)

revision: 2019-12-12

SECTION 6: Accidental release measures
6.1

personal precautions, protective equipment and emergency procedures
for non-emergency personnel
remove persons to safety.

for emergency responders
wear breathing apparatus if exposed to vapours/dust/spray/gases.

6.2

environmental precautions
keep away from drains, surface and ground water. retain contaminated washing water and dispose of it.

6.3

methods and material for containment and cleaning up
advice on how to contain a spillcovering of drains

advice on how to clean up a spill
wipe up with absorbent material (e.g. cloth, fleece). collect spillage: sawdust, kieselgur (diatomite), sand, universal binder

appropriate containment techniques
use of adsorbent materials.

other information relating to spills and releases
place in appropriate containers for disposal. ventilate affected area.

6.4

reference to other sections
personal protective equipment: see section 8. incompatible materials: see section 10. disposal considerations: see section
13.

SECTION 7: Handling and storage
7.1

precautions for safe handlingrecommendations- measures to prevent fire as well as aerosol and dust generation
use local and general ventilation. use only in well-ventilated areas.

advice on general occupational hygiene
wash hands after use. do not eat, drink and smoke in work areas. remove contaminated clothing and protective equipment
before entering eating areas. never keep food or drink in the vicinity of chemicals. never place chemicals in containers thatare normally used for food or drink. keep away from food, drink and animal feedingstuffs.

7.2

conditions for safe storage, including any incompatibilities
control of effects
protect against external exposure, such as
frost

7.3

specific end use(s)see section 16 for a general overview.

United Kingdom: en

page: 3 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

ChIP-seq grade GAPDH TSS primer pairversion number: GHS 3.0
replaces version of: 2019-12-12 (GHS 2)

revision: 2019-12-12

SECTION 8: Exposure controls/personal protection
8.1

control parameters
this information is not available.

8.2

exposure controls
appropriate engineering controls
general ventilation.

individual protection measures (personal protective equipment)eye/face protection
wear eye/face protection.

skin protection- hand protection
wear suitable gloves. chemical protection gloves are suitable, which are tested according to EN 374. check leak-tightness/
impermeability prior to use. in the case of wanting to use the gloves again, clean them before taking off and air them well.
for special purposes, it is recommended to check the resistance to chemicals of the protective gloves mentioned above together with the supplier of these gloves.

- other protection measurestake recovery periods for skin regeneration. preventive skin protection (barrier creams/ointments) is recommended. wash
hands thoroughly after handling.

respiratory protection
in case of inadequate ventilation wear respiratory protection.

environmental exposure controls
use appropriate container to avoid environmental contamination. keep away from drains, surface and ground water.

SECTION 9: Physical and chemical properties
9.1

information on basic physical and chemical properties
appearancephysical stateliquidcolourcolourlessodour

odourlessother safety parameters
pH (value)

not determinedmelting point/freezing point

not determined

initial boiling point and boiling range

not determinedflash point

not determined

evaporation rate

not determined

flammability (solid, gas)

not relevant, (fluid)

United Kingdom: en

page: 4 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

ChIP-seq grade GAPDH TSS primer pairversion number: GHS 3.0
replaces version of: 2019-12-12 (GHS 2)

revision: 2019-12-12

explosive limits

not determinedvapour pressure

not determined

density

not determinedvapour density

this information is not available

relative density

information on this property is not available

solubility(ies)not determinedpartition coefficient9.2- n-octanol/water (log KOW)

this information is not available

auto-ignition temperature

not determinedviscosity

not determined

explosive properties

none

oxidising properties

none

other information

there is no additional information

SECTION 10: Stability and reactivity
10.1

reactivity
concerning incompatibility: see below "Conditions to avoid" and "Incompatible materials".

10.2

chemical stability
the material is stable under normal ambient and anticipated storage and handling conditions of temperature and pressure.

10.3

possibility of hazardous reactions
no known hazardous reactions.

10.4

conditions to avoid
there are no specific conditions known which have to be avoided.

10.5

incompatible materials
there is no additional information.

10.6

hazardous decomposition products
reasonably anticipated hazardous decomposition products produced as a result of use, storage, spill and heating are notknown. hazardous combustion products: see section 5.

United Kingdom: en

page: 5 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

ChIP-seq grade GAPDH TSS primer pairversion number: GHS 3.0
replaces version of: 2019-12-12 (GHS 2)

revision: 2019-12-12

SECTION 11: Toxicological information
11.1

information on toxicological effects
test data are not available for the complete mixture.

classification procedurethe method for classification of the mixture is based on ingredients of the mixture (additivity formula).

classification according to GHS (1272/2008/EC, CLP)
this mixture does not meet the criteria for classification in accordance with Regulation No 1272/2008/EC.

acute toxicity
shall not be classified as acutely toxic.

skin corrosion/irritation
shall not be classified as corrosive/irritant to skin.

serious eye damage/eye irritation
shall not be classified as seriously damaging to the eye or eye irritant.

respiratory or skin sensitisation
shall not be classified as a respiratory or skin sensitiser.

germ cell mutagenicity
shall not be classified as germ cell mutagenic.

carcinogenicity
shall not be classified as carcinogenic.

reproductive toxicity
shall not be classified as a reproductive toxicant.

specific target organ toxicity - single exposure
shall not be classified as a specific target organ toxicant (single exposure).

specific target organ toxicity - repeated exposure
shall not be classified as a specific target organ toxicant (repeated exposure).

aspiration hazard
shall not be classified as presenting an aspiration hazard.

SECTION 12: Ecological information
12.1

toxicity
shall not be classified as hazardous to the aquatic environment.

12.2

persistence and degradability
data are not available.

12.3

bioaccumulative potential
data are not available.

12.4

mobility in soil
data are not available.

12.5

results of PBT and vPvB assessment
data are not available.

United Kingdom: en

page: 6 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

ChIP-seq grade GAPDH TSS primer pairversion number: GHS 3.0
replaces version of: 2019-12-12 (GHS 2)

12.6

revision: 2019-12-12

other adverse effects
data are not available.

SECTION 13: Disposal considerations
13.1

waste treatment methods
sewage disposal-relevant information
do not empty into drains. avoid release to the environment. Refer to special instructions/safety data sheets.

waste treatment of containers/packagingscompletely emptied packages can be recycled. handle contaminated packages in the same way as the substance itself.

remarks
please consider the relevant national or regional provisions. waste shall be separated into the categories that can behandled separately by the local or national waste management facilities.

SECTION 14: Transport information
14.1

UN numbernot subject to transport regulations

14.2

UN proper shipping namenot relevant

14.3

transport hazard class(es)

none

14.4

packing group

not assigned to a packing group

14.5

environmental hazards

non-environmentally hazardous acc. to the dangerous goods regulations

14.6

special precautions for user
there is no additional information.

14.7

transport in bulk according to Annex II of MARPOL and the IBC Codethe cargo is not intended to be carried in bulk.

Information for each of the UN Model Regulationstransport of dangerous goods by road, rail and inland waterway (ADR/RID/ADN)
not subject to ADR, RID and ADN.

International Maritime Dangerous Goods Code (IMDG)
not subject to IMDG.

International Civil Aviation Organization (ICAO-IATA/DGR)
not subject to ICAO-IATA.

SECTION 15: Regulatory information
15.1

safety, health and environmental regulations/legislation specific for the substance or mixture

15.2

Chemical Safety Assessment
chemical safety assessments for substances in this mixture were not carried out.

United Kingdom: en

page: 7 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)

ChIP-seq grade GAPDH TSS primer pairversion number: GHS 3.0
replaces version of: 2019-12-12 (GHS 2)

revision: 2019-12-12

SECTION 16: Other information
indication of changes (revised safety data sheet)sectionformer entry (text/value)

1.1

actual entry (text/value)safety-relevant

product code(s):C17011047

yesabbreviations and acronyms
abbr.

descriptions of used abbreviations

ADN

Accord européen relatif au transport international des marchandises dangereuses par voies de navigation
intérieures (European Agreement concerning the International Carriage of Dangerous Goods by Inland Waterways)

ADR

Accord européen relatif au transport international des marchandises dangereuses par route (European Agreement concerning the International Carriage of Dangerous Goods by Road)

CLP

Regulation (EC) No 1272/2008 on classification, labelling and packaging of substances and mixtures

DGR

Dangerous Goods Regulations (see IATA/DGR)

GHS"Globally Harmonized System of Classification and Labelling of Chemicals" developed by the United Nations

IATA

International Air Transport Association

IATA/DGR

Dangerous Goods Regulations (DGR) for the air transport (IATA)ICAOInternational Civil Aviation Organization

IMDG

International Maritime Dangerous Goods CodeMARPOLInternational Convention for the Prevention of Pollution from Ships (abbr. of "Marine Pollutant")

PBT

Persistent, Bioaccumulative and Toxic

REACH

Registration, Evaluation, Authorisation and Restriction of Chemicals

RID

Règlement concernant le transport International ferroviaire des marchandises Dangereuses (Regulations concerning the International carriage of Dangerous goods by Rail)vPvB

Very Persistent and very Bioaccumulative

key literature references and sources for data
Regulation (EC) No 1272/2008 on classification, labelling and packaging of substances and mixtures. Regulation (EC) No.
1907/2006 (REACH), amended by 2015/830/EU.
transport of dangerous goods by road, rail and inland waterway (ADR/RID/ADN). International Maritime Dangerous Goods
Code (IMDG). Dangerous Goods Regulations (DGR) for the air transport (IATA).

classification procedurephysical and chemical properties: the classification is based on tested mixture.
health hazards, environmental hazards: the method for classification of the mixture is based on ingredients of the mixture(additivity formula).

disclaimer
this information is based upon the present state of our knowledge. this SDS has been compiled and is solely intended for thisproduct.

United Kingdom: en

page: 8 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)GenDNA Digestion buffer
version number: GHS 1.0

date of compilation: 2020-04-01

SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1

1.2

product identifiertrade nameGenDNA Digestion buffer

registration number (REACH)

not relevant (mixture)

relevant identified uses of the substance or mixture and uses advised against
relevant identified uses

1.3

for research use only, not for use in diagnostic ortherapeutic procedures.

details of the supplier of the safety data sheet
Diagenode SA
LIEGE SCIENCE PARK Rue du Bois Saint-Jean, 34102 Seraing
Belgium
telephone: +32 4 364 20 50
e-mail: info@diagenode.com

1.4

emergency telephone number
emergency information service+32 4 364 20 50
this number is only available during the following office hours: Mon-Fri 09:00 AM - 05:00 PM

poison centre
country

nametelephone

United Kingdom

National Poisons Information Service

111

SECTION 2: Hazards identification
2.1

classification of the substance or mixture
classification according to Regulation (EC) No 1272/2008 (CLP)
this mixture does not meet the criteria for classification in accordance with Regulation No 1272/2008/EC.

2.2

label elements
labelling according to Regulation (EC) No 1272/2008 (CLP)
not required

2.3

other hazards
results of PBT and vPvB assessment
this mixture does not contain any substances that are assessed to be a PBT or a vPvB.

SECTION 3: Composition/information on ingredients
3.1

substances
not relevant (mixture)

3.2

mixturesdescription of the mixtureThis mixture does not contain any potentially hazardous products.

United Kingdom: en

page: 1 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)GenDNA Digestion buffer
version number: GHS 1.0

date of compilation: 2020-04-01

SECTION 4: First aid measures4.1

description of first aid measuresgeneral notes
do not leave affected person unattended. remove victim out of the danger area. keep affected person warm, still andcovered. take off immediately all contaminated clothing. in all cases of doubt, or when symptoms persist, seek medical advice. in case of unconsciousness place person in the recovery position. Never give anything by mouth.

following inhalation
if breathing is irregular or stopped, immediately seek medical assistance and start first aid actions. provide fresh air.

following skin contact
wash with plenty of soap and water.

following eye contact
remove contact lenses, if present and easy to do. Continue rinsing. irrigate copiously with clean, fresh water for at least 10
minutes, holding the eyelids apart.

following ingestionrinse mouth with water (only if the person is conscious). do NOT induce vomiting.

4.2

most important symptoms and effects, both acute and delayed
symptoms and effects are not known to date.

4.3

indication of any immediate medical attention and special treatment needed
none

SECTION 5: Firefighting measures
5.1

extinguishing media
suitable extinguishing media
water spray, BC-powder, carbon dioxide (CO2)

unsuitable extinguishing media
water jet

5.2

special hazards arising from the substance or mixture
hazardous combustion products
nitrogen oxides (NOx)

5.3

advice for firefightersin case of fire and/or explosion do not breathe fumes. co-ordinate firefighting measures to the fire surroundings. do not allow firefighting water to enter drains or water courses. collect contaminated firefighting water separately. fight fire withnormal precautions from a reasonable distance.

SECTION 6: Accidental release measures
6.1

personal precautions, protective equipment and emergency procedures
for non-emergency personnel
remove persons to safety.

for emergency responders
wear breathing apparatus if exposed to vapours/dust/spray/gases.

6.2

environmental precautions
keep away from drains, surface and ground water. retain contaminated washing water and dispose of it.

United Kingdom: en

page: 2 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)GenDNA Digestion buffer
version number: GHS 1.0

6.3

date of compilation: 2020-04-01

methods and material for containment and cleaning up
advice on how to contain a spillcovering of drains

advice on how to clean up a spill
wipe up with absorbent material (e.g. cloth, fleece). collect spillage: sawdust, kieselgur (diatomite), sand, universal binder

appropriate containment techniques
use of adsorbent materials.

other information relating to spills and releases
place in appropriate containers for disposal. ventilate affected area.

6.4

reference to other sections
hazardous combustion products: see section 5. personal protective equipment: see section 8. incompatible materials: seesection 10. disposal considerations: see section 13.

SECTION 7: Handling and storage
7.1

precautions for safe handlingrecommendations- measures to prevent fire as well as aerosol and dust generation
use local and general ventilation. use only in well-ventilated areas.

advice on general occupational hygiene
wash hands after use. do not eat, drink and smoke in work areas. remove contaminated clothing and protective equipment
before entering eating areas. never keep food or drink in the vicinity of chemicals. never place chemicals in containers thatare normally used for food or drink. keep away from food, drink and animal feedingstuffs.

7.2

conditions for safe storage, including any incompatibilities
control of effects
protect against external exposure, such as
frost

7.3

specific end use(s)see section 16 for a general overview.

SECTION 8: Exposure controls/personal protection
8.1

control parameters
this information is not available.

8.2

exposure controls
appropriate engineering controls
general ventilation.

individual protection measures (personal protective equipment)eye/face protection
wear eye/face protection.

United Kingdom: en

page: 3 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)GenDNA Digestion buffer
version number: GHS 1.0

date of compilation: 2020-04-01

skin protection- hand protection
wear suitable gloves. chemical protection gloves are suitable, which are tested according to EN 374. check leak-tightness/
impermeability prior to use. in the case of wanting to use the gloves again, clean them before taking off and air them well.
for special purposes, it is recommended to check the resistance to chemicals of the protective gloves mentioned above together with the supplier of these gloves.

- other protection measurestake recovery periods for skin regeneration. preventive skin protection (barrier creams/ointments) is recommended. wash
hands thoroughly after handling.

respiratory protection
in case of inadequate ventilation wear respiratory protection.

environmental exposure controls
use appropriate container to avoid environmental contamination. keep away from drains, surface and ground water.

SECTION 9: Physical and chemical properties
9.1

information on basic physical and chemical properties
appearancephysical stateliquidcolourcolourlessodour

odourlessother safety parameters
pH (value)

not determinedmelting point/freezing point

not determined

initial boiling point and boiling range

not determinedflash point

not determined

evaporation rate

not determined

flammability (solid, gas)

not relevant, (fluid)

explosive limits

not determinedvapour pressure

not determined

density

not determinedvapour density

this information is not available

relative density

information on this property is not available

solubility(ies)not determinedpartition coefficient- n-octanol/water (log KOW)
United Kingdom: enthis information is not available
page: 4 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)GenDNA Digestion buffer
version number: GHS 1.0

9.2

date of compilation: 2020-04-01

auto-ignition temperature

not determinedviscosity

not determined

explosive properties

none

oxidising properties

none

other information

there is no additional information

SECTION 10: Stability and reactivity
10.1

reactivity
concerning incompatibility: see below "Conditions to avoid" and "Incompatible materials".

10.2

chemical stability
the material is stable under normal ambient and anticipated storage and handling conditions of temperature and pressure.

10.3

possibility of hazardous reactions
no known hazardous reactions.

10.4

conditions to avoid
there are no specific conditions known which have to be avoided.

10.5

incompatible materials
there is no additional information.

10.6

hazardous decomposition products
reasonably anticipated hazardous decomposition products produced as a result of use, storage, spill and heating are notknown. hazardous combustion products: see section 5.

SECTION 11: Toxicological information
11.1

information on toxicological effects
test data are not available for the complete mixture.

classification procedurethe method for classification of the mixture is based on ingredients of the mixture (additivity formula).

classification according to GHS (1272/2008/EC, CLP)
this mixture does not meet the criteria for classification in accordance with Regulation No 1272/2008/EC.

acute toxicity
shall not be classified as acutely toxic.

skin corrosion/irritation
shall not be classified as corrosive/irritant to skin.

serious eye damage/eye irritation
shall not be classified as seriously damaging to the eye or eye irritant.

respiratory or skin sensitisation
shall not be classified as a respiratory or skin sensitiser.

germ cell mutagenicity
shall not be classified as germ cell mutagenic.

United Kingdom: en

page: 5 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)GenDNA Digestion buffer
version number: GHS 1.0

date of compilation: 2020-04-01

carcinogenicity
shall not be classified as carcinogenic.

reproductive toxicity
shall not be classified as a reproductive toxicant.

specific target organ toxicity - single exposure
shall not be classified as a specific target organ toxicant (single exposure).

specific target organ toxicity - repeated exposure
shall not be classified as a specific target organ toxicant (repeated exposure).

aspiration hazard
shall not be classified as presenting an aspiration hazard.

SECTION 12: Ecological information
12.1

toxicity
shall not be classified as hazardous to the aquatic environment.

12.2

persistence and degradability
data are not available.

12.3

bioaccumulative potential
data are not available.

12.4

mobility in soil
data are not available.

12.5

results of PBT and vPvB assessment
data are not available.

12.6

other adverse effects
data are not available.

SECTION 13: Disposal considerations
13.1

waste treatment methods
sewage disposal-relevant information
do not empty into drains. avoid release to the environment. Refer to special instructions/safety data sheets.

waste treatment of containers/packagingscompletely emptied packages can be recycled. handle contaminated packages in the same way as the substance itself.

remarks
please consider the relevant national or regional provisions. waste shall be separated into the categories that can behandled separately by the local or national waste management facilities.

United Kingdom: en

page: 6 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)GenDNA Digestion buffer
version number: GHS 1.0

date of compilation: 2020-04-01

SECTION 14: Transport information
14.1

UN numbernot subject to transport regulations

14.2

UN proper shipping namenot relevant

14.3

transport hazard class(es)

none

14.4

packing group

not assigned to a packing group

14.5

environmental hazards

non-environmentally hazardous acc. to the dangerous goods regulations

14.6

special precautions for user
there is no additional information.

14.7

transport in bulk according to Annex II of MARPOL and the IBC Codethe cargo is not intended to be carried in bulk.

Information for each of the UN Model Regulationstransport of dangerous goods by road, rail and inland waterway (ADR/RID/ADN)
not subject to ADR, RID and ADN.

International Maritime Dangerous Goods Code (IMDG)
not subject to IMDG.

International Civil Aviation Organization (ICAO-IATA/DGR)
not subject to ICAO-IATA.

SECTION 15: Regulatory information
15.1

safety, health and environmental regulations/legislation specific for the substance or mixture

15.2

Chemical Safety Assessment
chemical safety assessments for substances in this mixture were not carried out.

SECTION 16: Other informationabbreviations and acronyms
abbr.

descriptions of used abbreviations

ADN

Accord européen relatif au transport international des marchandises dangereuses par voies de navigation
intérieures (European Agreement concerning the International Carriage of Dangerous Goods by Inland Waterways)

ADR

Accord européen relatif au transport international des marchandises dangereuses par route (European Agreement concerning the International Carriage of Dangerous Goods by Road)

CLP

Regulation (EC) No 1272/2008 on classification, labelling and packaging of substances and mixtures

DGR

Dangerous Goods Regulations (see IATA/DGR)

GHS"Globally Harmonized System of Classification and Labelling of Chemicals" developed by the United Nations

IATA

International Air Transport Association

IATA/DGR

Dangerous Goods Regulations (DGR) for the air transport (IATA)ICAOInternational Civil Aviation Organization

IMDG

International Maritime Dangerous Goods CodeUnited Kingdom: en

page: 7 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)GenDNA Digestion buffer
version number: GHS 1.0

date of compilation: 2020-04-01

abbr.

descriptions of used abbreviations

MARPOLInternational Convention for the Prevention of Pollution from Ships (abbr. of "Marine Pollutant")

PBT

Persistent, Bioaccumulative and Toxic

REACH

Registration, Evaluation, Authorisation and Restriction of Chemicals

RID

Règlement concernant le transport International ferroviaire des marchandises Dangereuses (Regulations concerning the International carriage of Dangerous goods by Rail)vPvB

Very Persistent and very Bioaccumulative

key literature references and sources for data
Regulation (EC) No 1272/2008 on classification, labelling and packaging of substances and mixtures. Regulation (EC) No.
1907/2006 (REACH), amended by 2015/830/EU.
transport of dangerous goods by road, rail and inland waterway (ADR/RID/ADN). International Maritime Dangerous Goods
Code (IMDG). Dangerous Goods Regulations (DGR) for the air transport (IATA).

classification procedurephysical and chemical properties: the classification is based on tested mixture.
health hazards, environmental hazards: the method for classification of the mixture is based on ingredients of the mixture(additivity formula).

disclaimer
this information is based upon the present state of our knowledge. this SDS has been compiled and is solely intended for thisproduct.

United Kingdom: en

page: 8 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)GenDNA precipitantversion number: GHS 1.0

date of compilation: 2020-04-01

SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1

1.2

product identifiertrade nameGenDNA precipitantregistration number (REACH)

not relevant (mixture)

relevant identified uses of the substance or mixture and uses advised against
relevant identified uses

1.3

for research use only, not for use in diagnostic ortherapeutic procedures.

details of the supplier of the safety data sheet
Diagenode SA
LIEGE SCIENCE PARK Rue du Bois Saint-Jean, 34102 Seraing
Belgium
telephone: +32 4 364 20 50
e-mail: info@diagenode.com

1.4

emergency telephone number
emergency information service+32 4 364 20 50
this number is only available during the following office hours: Mon-Fri 09:00 AM - 05:00 PM

poison centre
country

nametelephone

United Kingdom

National Poisons Information Service

111

SECTION 2: Hazards identification
2.1

classification of the substance or mixture
classification according to Regulation (EC) No 1272/2008 (CLP)
this mixture does not meet the criteria for classification in accordance with Regulation No 1272/2008/EC.

2.2

label elements
labelling according to Regulation (EC) No 1272/2008 (CLP)
not required

2.3

other hazards
results of PBT and vPvB assessment
this mixture does not contain any substances that are assessed to be a PBT or a vPvB.

SECTION 3: Composition/information on ingredients
3.1

substances
not relevant (mixture)

3.2

mixturesdescription of the mixtureThis mixture does not contain any potentially hazardous products.

United Kingdom: en

page: 1 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)GenDNA precipitantversion number: GHS 1.0

date of compilation: 2020-04-01

SECTION 4: First aid measures4.1

description of first aid measuresgeneral notes
do not leave affected person unattended. remove victim out of the danger area. keep affected person warm, still andcovered. take off immediately all contaminated clothing. in all cases of doubt, or when symptoms persist, seek medical advice. in case of unconsciousness place person in the recovery position. Never give anything by mouth.

following inhalation
if breathing is irregular or stopped, immediately seek medical assistance and start first aid actions. provide fresh air.

following skin contact
wash with plenty of soap and water.

following eye contact
remove contact lenses, if present and easy to do. Continue rinsing. irrigate copiously with clean, fresh water for at least 10
minutes, holding the eyelids apart.

following ingestionrinse mouth with water (only if the person is conscious). do NOT induce vomiting.

4.2

most important symptoms and effects, both acute and delayed
symptoms and effects are not known to date.

4.3

indication of any immediate medical attention and special treatment needed
none

SECTION 5: Firefighting measures
5.1

extinguishing media
suitable extinguishing media
water spray, BC-powder, carbon dioxide (CO2)

unsuitable extinguishing media
water jet

5.2

special hazards arising from the substance or mixture
hazardous combustion products
carbon monoxide (CO), carbon dioxide (CO2)

5.3

advice for firefightersin case of fire and/or explosion do not breathe fumes. co-ordinate firefighting measures to the fire surroundings. do not allow firefighting water to enter drains or water courses. collect contaminated firefighting water separately. fight fire withnormal precautions from a reasonable distance.

SECTION 6: Accidental release measures
6.1

personal precautions, protective equipment and emergency procedures
for non-emergency personnel
remove persons to safety.

for emergency responders
wear breathing apparatus if exposed to vapours/dust/spray/gases.

6.2

environmental precautions
keep away from drains, surface and ground water. retain contaminated washing water and dispose of it.

United Kingdom: en

page: 2 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)GenDNA precipitantversion number: GHS 1.0

6.3

date of compilation: 2020-04-01

methods and material for containment and cleaning up
advice on how to contain a spillcovering of drains

advice on how to clean up a spill
wipe up with absorbent material (e.g. cloth, fleece). collect spillage: sawdust, kieselgur (diatomite), sand, universal binder

appropriate containment techniques
use of adsorbent materials.

other information relating to spills and releases
place in appropriate containers for disposal. ventilate affected area.

6.4

reference to other sections
hazardous combustion products: see section 5. personal protective equipment: see section 8. incompatible materials: seesection 10. disposal considerations: see section 13.

SECTION 7: Handling and storage
7.1

precautions for safe handlingrecommendations- measures to prevent fire as well as aerosol and dust generation
use local and general ventilation. use only in well-ventilated areas.

advice on general occupational hygiene
wash hands after use. do not eat, drink and smoke in work areas. remove contaminated clothing and protective equipment
before entering eating areas. never keep food or drink in the vicinity of chemicals. never place chemicals in containers thatare normally used for food or drink. keep away from food, drink and animal feedingstuffs.

7.2

conditions for safe storage, including any incompatibilities
control of effects
protect against external exposure, such as
frost

7.3

specific end use(s)see section 16 for a general overview.

SECTION 8: Exposure controls/personal protection
8.1

control parameters
this information is not available.

8.2

exposure controls
appropriate engineering controls
general ventilation.

individual protection measures (personal protective equipment)eye/face protection
wear eye/face protection.

United Kingdom: en

page: 3 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)GenDNA precipitantversion number: GHS 1.0

date of compilation: 2020-04-01

skin protection- hand protection
wear suitable gloves. chemical protection gloves are suitable, which are tested according to EN 374. check leak-tightness/
impermeability prior to use. in the case of wanting to use the gloves again, clean them before taking off and air them well.
for special purposes, it is recommended to check the resistance to chemicals of the protective gloves mentioned above together with the supplier of these gloves.

- other protection measurestake recovery periods for skin regeneration. preventive skin protection (barrier creams/ointments) is recommended. wash
hands thoroughly after handling.

respiratory protection
in case of inadequate ventilation wear respiratory protection.

environmental exposure controls
use appropriate container to avoid environmental contamination. keep away from drains, surface and ground water.

SECTION 9: Physical and chemical properties
9.1

information on basic physical and chemical properties
appearancephysical stateliquidcolourcolourlessodour

odourlessother safety parameters
pH (value)

not determinedmelting point/freezing point

not determined

initial boiling point and boiling range

not determinedflash point

not determined

evaporation rate

not determined

flammability (solid, gas)

not relevant, (fluid)

explosive limits

not determinedvapour pressure

not determined

density

not determinedvapour density

this information is not available

relative density

information on this property is not available

solubility(ies)not determinedpartition coefficient- n-octanol/water (log KOW)
United Kingdom: enthis information is not available
page: 4 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)GenDNA precipitantversion number: GHS 1.0

9.2

date of compilation: 2020-04-01

auto-ignition temperature

not determinedviscosity

not determined

explosive properties

none

oxidising properties

none

other information

there is no additional information

SECTION 10: Stability and reactivity
10.1

reactivity
concerning incompatibility: see below "Conditions to avoid" and "Incompatible materials".

10.2

chemical stability
the material is stable under normal ambient and anticipated storage and handling conditions of temperature and pressure.

10.3

possibility of hazardous reactions
no known hazardous reactions.

10.4

conditions to avoid
there are no specific conditions known which have to be avoided.

10.5

incompatible materials
oxidisers

10.6

hazardous decomposition products
reasonably anticipated hazardous decomposition products produced as a result of use, storage, spill and heating are notknown. hazardous combustion products: see section 5.

SECTION 11: Toxicological information
11.1

information on toxicological effects
test data are not available for the complete mixture.

classification procedurethe method for classification of the mixture is based on ingredients of the mixture (additivity formula).

classification according to GHS (1272/2008/EC, CLP)
this mixture does not meet the criteria for classification in accordance with Regulation No 1272/2008/EC.

acute toxicity
shall not be classified as acutely toxic.

skin corrosion/irritation
shall not be classified as corrosive/irritant to skin.

serious eye damage/eye irritation
shall not be classified as seriously damaging to the eye or eye irritant.

respiratory or skin sensitisation
shall not be classified as a respiratory or skin sensitiser.

germ cell mutagenicity
shall not be classified as germ cell mutagenic.

United Kingdom: en

page: 5 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)GenDNA precipitantversion number: GHS 1.0

date of compilation: 2020-04-01

carcinogenicity
shall not be classified as carcinogenic.

reproductive toxicity
shall not be classified as a reproductive toxicant.

specific target organ toxicity - single exposure
shall not be classified as a specific target organ toxicant (single exposure).

specific target organ toxicity - repeated exposure
shall not be classified as a specific target organ toxicant (repeated exposure).

aspiration hazard
shall not be classified as presenting an aspiration hazard.

SECTION 12: Ecological information
12.1

toxicity
shall not be classified as hazardous to the aquatic environment.

12.2

persistence and degradability
data are not available.

12.3

bioaccumulative potential
data are not available.

12.4

mobility in soil
data are not available.

12.5

results of PBT and vPvB assessment
data are not available.

12.6

other adverse effects
data are not available.

SECTION 13: Disposal considerations
13.1

waste treatment methods
sewage disposal-relevant information
do not empty into drains. avoid release to the environment. Refer to special instructions/safety data sheets.

waste treatment of containers/packagingscompletely emptied packages can be recycled. handle contaminated packages in the same way as the substance itself.

remarks
please consider the relevant national or regional provisions. waste shall be separated into the categories that can behandled separately by the local or national waste management facilities.

United Kingdom: en

page: 6 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)GenDNA precipitantversion number: GHS 1.0

date of compilation: 2020-04-01

SECTION 14: Transport information
14.1

UN numbernot subject to transport regulations

14.2

UN proper shipping namenot relevant

14.3

transport hazard class(es)

none

14.4

packing group

not assigned to a packing group

14.5

environmental hazards

non-environmentally hazardous acc. to the dangerous goods regulations

14.6

special precautions for user
there is no additional information.

14.7

transport in bulk according to Annex II of MARPOL and the IBC Codethe cargo is not intended to be carried in bulk.

Information for each of the UN Model Regulationstransport of dangerous goods by road, rail and inland waterway (ADR/RID/ADN)
not subject to ADR, RID and ADN.

International Maritime Dangerous Goods Code (IMDG)
not subject to IMDG.

International Civil Aviation Organization (ICAO-IATA/DGR)
not subject to ICAO-IATA.

SECTION 15: Regulatory information
15.1

safety, health and environmental regulations/legislation specific for the substance or mixture

15.2

Chemical Safety Assessment
chemical safety assessments for substances in this mixture were not carried out.

SECTION 16: Other informationabbreviations and acronyms
abbr.

descriptions of used abbreviations

ADN

Accord européen relatif au transport international des marchandises dangereuses par voies de navigation
intérieures (European Agreement concerning the International Carriage of Dangerous Goods by Inland Waterways)

ADR

Accord européen relatif au transport international des marchandises dangereuses par route (European Agreement concerning the International Carriage of Dangerous Goods by Road)

CLP

Regulation (EC) No 1272/2008 on classification, labelling and packaging of substances and mixtures

DGR

Dangerous Goods Regulations (see IATA/DGR)

GHS"Globally Harmonized System of Classification and Labelling of Chemicals" developed by the United Nations

IATA

International Air Transport Association

IATA/DGR

Dangerous Goods Regulations (DGR) for the air transport (IATA)ICAOInternational Civil Aviation Organization

IMDG

International Maritime Dangerous Goods CodeUnited Kingdom: en

page: 7 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)GenDNA precipitantversion number: GHS 1.0

date of compilation: 2020-04-01

abbr.

descriptions of used abbreviations

MARPOLInternational Convention for the Prevention of Pollution from Ships (abbr. of "Marine Pollutant")

PBT

Persistent, Bioaccumulative and Toxic

REACH

Registration, Evaluation, Authorisation and Restriction of Chemicals

RID

Règlement concernant le transport International ferroviaire des marchandises Dangereuses (Regulations concerning the International carriage of Dangerous goods by Rail)vPvB

Very Persistent and very Bioaccumulative

key literature references and sources for data
Regulation (EC) No 1272/2008 on classification, labelling and packaging of substances and mixtures. Regulation (EC) No.
1907/2006 (REACH), amended by 2015/830/EU.
transport of dangerous goods by road, rail and inland waterway (ADR/RID/ADN). International Maritime Dangerous Goods
Code (IMDG). Dangerous Goods Regulations (DGR) for the air transport (IATA).

classification procedurephysical and chemical properties: the classification is based on tested mixture.
health hazards, environmental hazards: the method for classification of the mixture is based on ingredients of the mixture(additivity formula).

disclaimer
this information is based upon the present state of our knowledge. this SDS has been compiled and is solely intended for thisproduct.

United Kingdom: en

page: 8 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)GenDNA TE
version number: GHS 1.0

date of compilation: 2020-04-01

SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1

1.2

product identifiertrade nameGenDNA TE

registration number (REACH)

not relevant (mixture)

relevant identified uses of the substance or mixture and uses advised against
relevant identified uses

1.3

for research use only, not for use in diagnostic ortherapeutic procedures.

details of the supplier of the safety data sheet
Diagenode SA
LIEGE SCIENCE PARK Rue du Bois Saint-Jean, 34102 Seraing
Belgium
telephone: +32 4 364 20 50
e-mail: info@diagenode.com

1.4

emergency telephone number
emergency information service+32 4 364 20 50
this number is only available during the following office hours: Mon-Fri 09:00 AM - 05:00 PM

poison centre
country

nametelephone

United Kingdom

National Poisons Information Service

111

SECTION 2: Hazards identification
2.1

classification of the substance or mixture
classification according to Regulation (EC) No 1272/2008 (CLP)
this mixture does not meet the criteria for classification in accordance with Regulation No 1272/2008/EC.

2.2

label elements
labelling according to Regulation (EC) No 1272/2008 (CLP)
not required

2.3

other hazards
results of PBT and vPvB assessment
this mixture does not contain any substances that are assessed to be a PBT or a vPvB.

SECTION 3: Composition/information on ingredients
3.1

substances
not relevant (mixture)

3.2

mixturesdescription of the mixtureThis mixture does not contain any potentially hazardous products.

United Kingdom: en

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Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)GenDNA TE
version number: GHS 1.0

date of compilation: 2020-04-01

SECTION 4: First aid measures4.1

description of first aid measuresgeneral notes
do not leave affected person unattended. remove victim out of the danger area. keep affected person warm, still andcovered. take off immediately all contaminated clothing. in all cases of doubt, or when symptoms persist, seek medical advice. in case of unconsciousness place person in the recovery position. Never give anything by mouth.

following inhalation
if breathing is irregular or stopped, immediately seek medical assistance and start first aid actions. provide fresh air.

following skin contact
wash with plenty of soap and water.

following eye contact
remove contact lenses, if present and easy to do. Continue rinsing. irrigate copiously with clean, fresh water for at least 10
minutes, holding the eyelids apart.

following ingestionrinse mouth with water (only if the person is conscious). do NOT induce vomiting.

4.2

most important symptoms and effects, both acute and delayed
symptoms and effects are not known to date.

4.3

indication of any immediate medical attention and special treatment needed
none

SECTION 5: Firefighting measures
5.1

extinguishing media
suitable extinguishing media
water spray, BC-powder, carbon dioxide (CO2)

unsuitable extinguishing media
water jet

5.2

special hazards arising from the substance or mixture
hazardous combustion products
nitrogen oxides (NOx)

5.3

advice for firefightersin case of fire and/or explosion do not breathe fumes. co-ordinate firefighting measures to the fire surroundings. do not allow firefighting water to enter drains or water courses. collect contaminated firefighting water separately. fight fire withnormal precautions from a reasonable distance.

SECTION 6: Accidental release measures
6.1

personal precautions, protective equipment and emergency procedures
for non-emergency personnel
remove persons to safety.

for emergency responders
wear breathing apparatus if exposed to vapours/dust/spray/gases.

6.2

environmental precautions
keep away from drains, surface and ground water. retain contaminated washing water and dispose of it.

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Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)GenDNA TE
version number: GHS 1.0

6.3

date of compilation: 2020-04-01

methods and material for containment and cleaning up
advice on how to contain a spillcovering of drains

advice on how to clean up a spill
wipe up with absorbent material (e.g. cloth, fleece). collect spillage: sawdust, kieselgur (diatomite), sand, universal binder

appropriate containment techniques
use of adsorbent materials.

other information relating to spills and releases
place in appropriate containers for disposal. ventilate affected area.

6.4

reference to other sections
hazardous combustion products: see section 5. personal protective equipment: see section 8. incompatible materials: seesection 10. disposal considerations: see section 13.

SECTION 7: Handling and storage
7.1

precautions for safe handlingrecommendations- measures to prevent fire as well as aerosol and dust generation
use local and general ventilation. use only in well-ventilated areas.

advice on general occupational hygiene
wash hands after use. do not eat, drink and smoke in work areas. remove contaminated clothing and protective equipment
before entering eating areas. never keep food or drink in the vicinity of chemicals. never place chemicals in containers thatare normally used for food or drink. keep away from food, drink and animal feedingstuffs.

7.2

conditions for safe storage, including any incompatibilities
control of effects
protect against external exposure, such as
frost

7.3

specific end use(s)see section 16 for a general overview.

SECTION 8: Exposure controls/personal protection
8.1

control parameters
this information is not available.

8.2

exposure controls
appropriate engineering controls
general ventilation.

individual protection measures (personal protective equipment)eye/face protection
wear eye/face protection.

United Kingdom: en

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Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)GenDNA TE
version number: GHS 1.0

date of compilation: 2020-04-01

skin protection- hand protection
wear suitable gloves. chemical protection gloves are suitable, which are tested according to EN 374. check leak-tightness/
impermeability prior to use. in the case of wanting to use the gloves again, clean them before taking off and air them well.
for special purposes, it is recommended to check the resistance to chemicals of the protective gloves mentioned above together with the supplier of these gloves.

- other protection measurestake recovery periods for skin regeneration. preventive skin protection (barrier creams/ointments) is recommended. wash
hands thoroughly after handling.

respiratory protection
in case of inadequate ventilation wear respiratory protection.

environmental exposure controls
use appropriate container to avoid environmental contamination. keep away from drains, surface and ground water.

SECTION 9: Physical and chemical properties
9.1

information on basic physical and chemical properties
appearancephysical stateliquidcolourcolourlessodour

odourlessother safety parameters
pH (value)

not determinedmelting point/freezing point

not determined

initial boiling point and boiling range

not determinedflash point

not determined

evaporation rate

not determined

flammability (solid, gas)

not relevant, (fluid)

explosive limits

not determinedvapour pressure

not determined

density

not determinedvapour density

this information is not available

relative density

information on this property is not available

solubility(ies)not determinedpartition coefficient- n-octanol/water (log KOW)
United Kingdom: enthis information is not available
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Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)GenDNA TE
version number: GHS 1.0

9.2

date of compilation: 2020-04-01

auto-ignition temperature

not determinedviscosity

not determined

explosive properties

none

oxidising properties

none

other information

there is no additional information

SECTION 10: Stability and reactivity
10.1

reactivity
concerning incompatibility: see below "Conditions to avoid" and "Incompatible materials".

10.2

chemical stability
the material is stable under normal ambient and anticipated storage and handling conditions of temperature and pressure.

10.3

possibility of hazardous reactions
no known hazardous reactions.

10.4

conditions to avoid
there are no specific conditions known which have to be avoided.

10.5

incompatible materials
there is no additional information.

10.6

hazardous decomposition products
reasonably anticipated hazardous decomposition products produced as a result of use, storage, spill and heating are notknown. hazardous combustion products: see section 5.

SECTION 11: Toxicological information
11.1

information on toxicological effects
test data are not available for the complete mixture.

classification procedurethe method for classification of the mixture is based on ingredients of the mixture (additivity formula).

classification according to GHS (1272/2008/EC, CLP)
this mixture does not meet the criteria for classification in accordance with Regulation No 1272/2008/EC.

acute toxicity
shall not be classified as acutely toxic.

skin corrosion/irritation
shall not be classified as corrosive/irritant to skin.

serious eye damage/eye irritation
shall not be classified as seriously damaging to the eye or eye irritant.

respiratory or skin sensitisation
shall not be classified as a respiratory or skin sensitiser.

germ cell mutagenicity
shall not be classified as germ cell mutagenic.

United Kingdom: en

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Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)GenDNA TE
version number: GHS 1.0

date of compilation: 2020-04-01

carcinogenicity
shall not be classified as carcinogenic.

reproductive toxicity
shall not be classified as a reproductive toxicant.

specific target organ toxicity - single exposure
shall not be classified as a specific target organ toxicant (single exposure).

specific target organ toxicity - repeated exposure
shall not be classified as a specific target organ toxicant (repeated exposure).

aspiration hazard
shall not be classified as presenting an aspiration hazard.

SECTION 12: Ecological information
12.1

toxicity
shall not be classified as hazardous to the aquatic environment.

12.2

persistence and degradability
data are not available.

12.3

bioaccumulative potential
data are not available.

12.4

mobility in soil
data are not available.

12.5

results of PBT and vPvB assessment
data are not available.

12.6

other adverse effects
data are not available.

SECTION 13: Disposal considerations
13.1

waste treatment methods
sewage disposal-relevant information
do not empty into drains. avoid release to the environment. Refer to special instructions/safety data sheets.

waste treatment of containers/packagingscompletely emptied packages can be recycled. handle contaminated packages in the same way as the substance itself.

remarks
please consider the relevant national or regional provisions. waste shall be separated into the categories that can behandled separately by the local or national waste management facilities.

United Kingdom: en

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Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)GenDNA TE
version number: GHS 1.0

date of compilation: 2020-04-01

SECTION 14: Transport information
14.1

UN numbernot subject to transport regulations

14.2

UN proper shipping namenot relevant

14.3

transport hazard class(es)

none

14.4

packing group

not assigned to a packing group

14.5

environmental hazards

non-environmentally hazardous acc. to the dangerous goods regulations

14.6

special precautions for user
there is no additional information.

14.7

transport in bulk according to Annex II of MARPOL and the IBC Codethe cargo is not intended to be carried in bulk.

Information for each of the UN Model Regulationstransport of dangerous goods by road, rail and inland waterway (ADR/RID/ADN)
not subject to ADR, RID and ADN.

International Maritime Dangerous Goods Code (IMDG)
not subject to IMDG.

International Civil Aviation Organization (ICAO-IATA/DGR)
not subject to ICAO-IATA.

SECTION 15: Regulatory information
15.1

safety, health and environmental regulations/legislation specific for the substance or mixture

15.2

Chemical Safety Assessment
chemical safety assessments for substances in this mixture were not carried out.

SECTION 16: Other informationabbreviations and acronyms
abbr.

descriptions of used abbreviations

ADN

Accord européen relatif au transport international des marchandises dangereuses par voies de navigation
intérieures (European Agreement concerning the International Carriage of Dangerous Goods by Inland Waterways)

ADR

Accord européen relatif au transport international des marchandises dangereuses par route (European Agreement concerning the International Carriage of Dangerous Goods by Road)

CLP

Regulation (EC) No 1272/2008 on classification, labelling and packaging of substances and mixtures

DGR

Dangerous Goods Regulations (see IATA/DGR)

GHS"Globally Harmonized System of Classification and Labelling of Chemicals" developed by the United Nations

IATA

International Air Transport Association

IATA/DGR

Dangerous Goods Regulations (DGR) for the air transport (IATA)ICAOInternational Civil Aviation Organization

IMDG

International Maritime Dangerous Goods CodeUnited Kingdom: en

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Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)GenDNA TE
version number: GHS 1.0

date of compilation: 2020-04-01

abbr.

descriptions of used abbreviations

MARPOLInternational Convention for the Prevention of Pollution from Ships (abbr. of "Marine Pollutant")

PBT

Persistent, Bioaccumulative and Toxic

REACH

Registration, Evaluation, Authorisation and Restriction of Chemicals

RID

Règlement concernant le transport International ferroviaire des marchandises Dangereuses (Regulations concerning the International carriage of Dangerous goods by Rail)vPvB

Very Persistent and very Bioaccumulative

key literature references and sources for data
Regulation (EC) No 1272/2008 on classification, labelling and packaging of substances and mixtures. Regulation (EC) No.
1907/2006 (REACH), amended by 2015/830/EU.
transport of dangerous goods by road, rail and inland waterway (ADR/RID/ADN). International Maritime Dangerous Goods
Code (IMDG). Dangerous Goods Regulations (DGR) for the air transport (IATA).

classification procedurephysical and chemical properties: the classification is based on tested mixture.
health hazards, environmental hazards: the method for classification of the mixture is based on ingredients of the mixture(additivity formula).

disclaimer
this information is based upon the present state of our knowledge. this SDS has been compiled and is solely intended for thisproduct.

United Kingdom: en

page: 8 / 8

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)GenDNA RNAse (DNAse-free)version number: GHS 1.0

date of compilation: 2020-04-01

SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1

1.2

product identifiertrade nameGenDNA RNAse (DNAse-free)registration number (REACH)

not relevant (mixture)

product code(s)C06060010

relevant identified uses of the substance or mixture and uses advised against
relevant identified uses

1.3

for research use only, not for use in diagnostic ortherapeutic procedures.

details of the supplier of the safety data sheet
Diagenode SA
LIEGE SCIENCE PARK Rue du Bois Saint-Jean, 34102 Seraing
Belgium
telephone: +32 4 364 20 50
e-mail: info@diagenode.com

1.4

emergency telephone number
emergency information service+32 4 364 20 50
this number is only available during the following office hours: Mon-Fri 09:00 AM - 05:00 PM

poison centre
country

nametelephone

United Kingdom

National Poisons Information Service

111

SECTION 2: Hazards identification
2.1

classification of the substance or mixture
classification according to Regulation (EC) No 1272/2008 (CLP)
this mixture does not meet the criteria for classification in accordance with Regulation No 1272/2008/EC.

2.2

label elements
labelling according to Regulation (EC) No 1272/2008 (CLP)
not required

2.3

other hazards
results of PBT and vPvB assessment
this mixture does not contain any substances that are assessed to be a PBT or a vPvB.

United Kingdom: en

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Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)GenDNA RNAse (DNAse-free)version number: GHS 1.0

date of compilation: 2020-04-01

SECTION 3: Composition/information on ingredients
3.1

substances
not relevant (mixture)

3.2

mixturesdescription of the mixtureThis mixture does not contain any potentially hazardous products.

SECTION 4: First aid measures4.1

description of first aid measuresgeneral notes
do not leave affected person unattended. remove victim out of the danger area. keep affected person warm, still andcovered. take off immediately all contaminated clothing. in all cases of doubt, or when symptoms persist, seek medical advice. in case of unconsciousness place person in the recovery position. Never give anything by mouth.

following inhalation
if breathing is irregular or stopped, immediately seek medical assistance and start first aid actions. provide fresh air.

following skin contact
wash with plenty of soap and water.

following eye contact
remove contact lenses, if present and easy to do. Continue rinsing. irrigate copiously with clean, fresh water for at least 10
minutes, holding the eyelids apart.

following ingestionrinse mouth with water (only if the person is conscious). do NOT induce vomiting.

4.2

most important symptoms and effects, both acute and delayed
symptoms and effects are not known to date.

4.3

indication of any immediate medical attention and special treatment needed
none

SECTION 5: Firefighting measures
5.1

extinguishing media
suitable extinguishing media
water spray, BC-powder, carbon dioxide (CO2)

unsuitable extinguishing media
water jet

5.2

special hazards arising from the substance or mixture
hazardous combustion products
carbon monoxide (CO), carbon dioxide (CO2)

5.3

advice for firefightersin case of fire and/or explosion do not breathe fumes. co-ordinate firefighting measures to the fire surroundings. do not allow firefighting water to enter drains or water courses. collect contaminated firefighting water separately. fight fire withnormal precautions from a reasonable distance.

United Kingdom: en

page: 2 / 9

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)GenDNA RNAse (DNAse-free)version number: GHS 1.0

date of compilation: 2020-04-01

SECTION 6: Accidental release measures
6.1

personal precautions, protective equipment and emergency procedures
for non-emergency personnel
remove persons to safety.

for emergency responders
wear breathing apparatus if exposed to vapours/dust/spray/gases.

6.2

environmental precautions
keep away from drains, surface and ground water. retain contaminated washing water and dispose of it.

6.3

methods and material for containment and cleaning up
advice on how to contain a spillcovering of drains

advice on how to clean up a spill
wipe up with absorbent material (e.g. cloth, fleece). collect spillage: sawdust, kieselgur (diatomite), sand, universal binder

appropriate containment techniques
use of adsorbent materials.

other information relating to spills and releases
place in appropriate containers for disposal. ventilate affected area.

6.4

reference to other sections
hazardous combustion products: see section 5. personal protective equipment: see section 8. incompatible materials: seesection 10. disposal considerations: see section 13.

SECTION 7: Handling and storage
7.1

precautions for safe handlingrecommendations- measures to prevent fire as well as aerosol and dust generation
use local and general ventilation. use only in well-ventilated areas.

advice on general occupational hygiene
wash hands after use. do not eat, drink and smoke in work areas. remove contaminated clothing and protective equipment
before entering eating areas. never keep food or drink in the vicinity of chemicals. never place chemicals in containers thatare normally used for food or drink. keep away from food, drink and animal feedingstuffs.

7.2

conditions for safe storage, including any incompatibilities
control of effects
protect against external exposure, such as
frost

7.3

specific end use(s)see section 16 for a general overview.

United Kingdom: en

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Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)GenDNA RNAse (DNAse-free)version number: GHS 1.0

date of compilation: 2020-04-01

SECTION 8: Exposure controls/personal protection
8.1

control parameters
occupational exposure limit values (Workplace Exposure Limits)country

name of agent

CAS NoidentifierGB

glycerol

56-81-5

WEL

TWA
[ppm]

TWA
[mg/m³]

STEL
[ppm]

10

STEL Ceiling-C Ceiling-C nota[mg/m³] [ppm] [mg/m³] tion

source

mist

EH40/
2005

notation
Ceiling-C
mist
STEL
TWA

8.2

ceiling value is a limit value above which exposure should not occur
as mists
short-term exposure limit: a limit value above which exposure should not occur and which is related to a 15-minute period (unless otherwise specified)time-weighted average (long-term exposure limit): measured or calculated in relation to a reference period of 8 hours timeweighted average (unless otherwise specified)

exposure controls
appropriate engineering controls
general ventilation.

individual protection measures (personal protective equipment)eye/face protection
wear eye/face protection.

skin protection- hand protection
wear suitable gloves. chemical protection gloves are suitable, which are tested according to EN 374. check leak-tightness/
impermeability prior to use. in the case of wanting to use the gloves again, clean them before taking off and air them well.
for special purposes, it is recommended to check the resistance to chemicals of the protective gloves mentioned above together with the supplier of these gloves.

- other protection measurestake recovery periods for skin regeneration. preventive skin protection (barrier creams/ointments) is recommended. wash
hands thoroughly after handling.

respiratory protection
in case of inadequate ventilation wear respiratory protection.

environmental exposure controls
use appropriate container to avoid environmental contamination. keep away from drains, surface and ground water.

SECTION 9: Physical and chemical properties
9.1

information on basic physical and chemical properties
appearancephysical stateliquidcolourcolourlessodour

odourless

United Kingdom: en

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Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)GenDNA RNAse (DNAse-free)version number: GHS 1.0

date of compilation: 2020-04-01

other safety parameters
pH (value)

not determinedmelting point/freezing point

not determined

initial boiling point and boiling range

not determinedflash point

not determined

evaporation rate

not determined

flammability (solid, gas)

not relevant, (fluid)

explosive limits

not determinedvapour pressure

not determined

density

not determinedvapour density

this information is not available

relative density

information on this property is not available

solubility(ies)not determinedpartition coefficient9.2- n-octanol/water (log KOW)

this information is not available

auto-ignition temperature

not determinedviscosity

not determined

explosive properties

none

oxidising properties

none

other information

there is no additional information

SECTION 10: Stability and reactivity
10.1

reactivity
concerning incompatibility: see below "Conditions to avoid" and "Incompatible materials".

10.2

chemical stability
the material is stable under normal ambient and anticipated storage and handling conditions of temperature and pressure.

10.3

possibility of hazardous reactions
no known hazardous reactions.

10.4

conditions to avoid
there are no specific conditions known which have to be avoided.

10.5

incompatible materials
oxidisers

United Kingdom: en

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Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)GenDNA RNAse (DNAse-free)version number: GHS 1.0

10.6

date of compilation: 2020-04-01

hazardous decomposition products
reasonably anticipated hazardous decomposition products produced as a result of use, storage, spill and heating are notknown. hazardous combustion products: see section 5.

SECTION 11: Toxicological information
11.1

information on toxicological effects
test data are not available for the complete mixture.

classification procedurethe method for classification of the mixture is based on ingredients of the mixture (additivity formula).

classification according to GHS (1272/2008/EC, CLP)
this mixture does not meet the criteria for classification in accordance with Regulation No 1272/2008/EC.

acute toxicity
shall not be classified as acutely toxic.

skin corrosion/irritation
shall not be classified as corrosive/irritant to skin.

serious eye damage/eye irritation
shall not be classified as seriously damaging to the eye or eye irritant.

respiratory or skin sensitisation
shall not be classified as a respiratory or skin sensitiser.

germ cell mutagenicity
shall not be classified as germ cell mutagenic.

carcinogenicity
shall not be classified as carcinogenic.

reproductive toxicity
shall not be classified as a reproductive toxicant.

specific target organ toxicity - single exposure
shall not be classified as a specific target organ toxicant (single exposure).

specific target organ toxicity - repeated exposure
shall not be classified as a specific target organ toxicant (repeated exposure).

aspiration hazard
shall not be classified as presenting an aspiration hazard.

SECTION 12: Ecological information
12.1

toxicity
shall not be classified as hazardous to the aquatic environment.

12.2

persistence and degradability
data are not available.

12.3

bioaccumulative potential
data are not available.

12.4

mobility in soil
data are not available.

United Kingdom: en

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Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)GenDNA RNAse (DNAse-free)version number: GHS 1.0

12.5

date of compilation: 2020-04-01

results of PBT and vPvB assessment
data are not available.

12.6

other adverse effects
data are not available.

SECTION 13: Disposal considerations
13.1

waste treatment methods
sewage disposal-relevant information
do not empty into drains. avoid release to the environment. Refer to special instructions/safety data sheets.

waste treatment of containers/packagingscompletely emptied packages can be recycled. handle contaminated packages in the same way as the substance itself.

remarks
please consider the relevant national or regional provisions. waste shall be separated into the categories that can behandled separately by the local or national waste management facilities.

SECTION 14: Transport information
14.1

UN numbernot subject to transport regulations

14.2

UN proper shipping namenot relevant

14.3

transport hazard class(es)

none

14.4

packing group

not assigned to a packing group

14.5

environmental hazards

non-environmentally hazardous acc. to the dangerous goods regulations

14.6

special precautions for user
there is no additional information.

14.7

transport in bulk according to Annex II of MARPOL and the IBC Codethe cargo is not intended to be carried in bulk.

Information for each of the UN Model Regulationstransport of dangerous goods by road, rail and inland waterway (ADR/RID/ADN)
not subject to ADR, RID and ADN.

International Maritime Dangerous Goods Code (IMDG)
not subject to IMDG.

International Civil Aviation Organization (ICAO-IATA/DGR)
not subject to ICAO-IATA.

United Kingdom: en

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Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)GenDNA RNAse (DNAse-free)version number: GHS 1.0

date of compilation: 2020-04-01

SECTION 15: Regulatory information
15.1

safety, health and environmental regulations/legislation specific for the substance or mixture

15.2

Chemical Safety Assessment
chemical safety assessments for substances in this mixture were not carried out.

SECTION 16: Other informationabbreviations and acronyms
abbr.

descriptions of used abbreviations

ADN

Accord européen relatif au transport international des marchandises dangereuses par voies de navigation
intérieures (European Agreement concerning the International Carriage of Dangerous Goods by Inland Waterways)

ADR

Accord européen relatif au transport international des marchandises dangereuses par route (European Agreement concerning the International Carriage of Dangerous Goods by Road)CAS

Chemical Abstracts Service (service that maintains the most comprehensive list of chemical substances)

Ceiling-C

Ceiling value

CLP

Regulation (EC) No 1272/2008 on classification, labelling and packaging of substances and mixtures

DGR

Dangerous Goods Regulations (see IATA/DGR)

EH40/2005

EH40/2005 Workplace exposure limits (http://www.nationalarchives.gov.uk/doc/open-government-licence/)

GHS"Globally Harmonized System of Classification and Labelling of Chemicals" developed by the United Nations

IATA

International Air Transport Association

IATA/DGR

Dangerous Goods Regulations (DGR) for the air transport (IATA)ICAOInternational Civil Aviation Organization

IMDG

International Maritime Dangerous Goods CodeMARPOLInternational Convention for the Prevention of Pollution from Ships (abbr. of "Marine Pollutant")

PBT

Persistent, Bioaccumulative and Toxic

ppm

Parts per million

REACH

Registration, Evaluation, Authorisation and Restriction of Chemicals

RID

Règlement concernant le transport International ferroviaire des marchandises Dangereuses (Regulations concerning the International carriage of Dangerous goods by Rail)STEL

Short-term exposure limit

TWA

Time-weighted averagevPvB

Very Persistent and very Bioaccumulative

WEL

Workplace exposure limit

key literature references and sources for data
Regulation (EC) No 1272/2008 on classification, labelling and packaging of substances and mixtures. Regulation (EC) No.
1907/2006 (REACH), amended by 2015/830/EU.
transport of dangerous goods by road, rail and inland waterway (ADR/RID/ADN). International Maritime Dangerous Goods
Code (IMDG). Dangerous Goods Regulations (DGR) for the air transport (IATA).

classification procedurephysical and chemical properties: the classification is based on tested mixture.
health hazards, environmental hazards: the method for classification of the mixture is based on ingredients of the mixture(additivity formula).
United Kingdom: en

page: 8 / 9

Safety Data Sheetaccording to Regulation (EC) No. 1907/2006 (REACH)GenDNA RNAse (DNAse-free)version number: GHS 1.0

date of compilation: 2020-04-01

disclaimer
this information is based upon the present state of our knowledge. this SDS has been compiled and is solely intended for thisproduct.

United Kingdom: en

page: 9 / 9