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úËõ July 2015 Vol.28 No.4  175

Synchrotron Radiation Facilities support for ``The
Platform for Drug Discovery, Informatics, andStructural Life Science'' project, which is availa­
ble for life scientists in Japan
Fumiaki YUMOTO

Structural Biology Research Center, Institute of Materials Structure Science, KEK/High Energy Accelerator Research Organization
Oho 1_1, Tsukuba City, Ibaraki 305_0801, JapanToshiya SENDA

Structural Biology Research Center, Institute of Materials Structure Science, KEK/High Energy Accelerator Research Organization
Oho 1_1, Tsukuba City, Ibaraki 305_0801, JapanAbstract

Synchrotron X_ray has been applied to protein crystallography in Japan since 1980s. The beamlines and the instruments in the Photon Factory (KEK/High Energy Accelerator Research Organi­zation) and SPring­8 (RIKEN) have been developed to keep them in the state of the art throughnational structural genomics projects such as ``Tanpaku 3000 (Protein 3000)'' and ``Target Tan­paku (Target Protein)'' from 2002. The serial ve years projects were supported by the Ministryof Education, Culture, Sports, Science & Technology (MEXT). Then, ``the Platform for Drug Dis­covery, Informatics, and Structural Life Science, PDIS'' has been launched since 2012. It started
with a variety of scientists who have dierent expertise such as bioinformatics, protein produc­tion, small molecule screening, organic synthesis, or protein structure determination with X_ray
crystallography, Small Angle X_ray Scattering (SAXS), NMR, or Cryo_EM. Furthermore, func­
tional genomics area was incorporated into the PDIS project since 2014.
The project was taken over by Japan Agency for Medical Research and Development (AMED)
since April in this year. It is opened for all life scientists not only from academia but also from in­dustries in Japan. It supports ``your'' scientic project with developing cutting edge technologies
in informatics, drug discovery, and structural life science.

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