Self-assembly of Carbohydrate Block Copolymers:
From glyconanoparticles to thin films to photonic crystals
Redouane Borsali
University Grenoble Alpes, CNRS, CERMAV, 38000, Grenoble, Francee-mail: redouane.borsali@univ-grenoble-alpes.fr
To date, numerous studies have been focused on the self-assembly of petroleum-based BCPs for potential
applications in multidisciplinary fields, such as nanoparticles for drug delivery, or nano-organized films forbiosensors, or nanolithography, etc. Such materials are derived from fossil resources that are being rapidlydepleted and have negative environmental impacts. In contrast, carbohydrates are abundant, renewable andconstitute a sustainable source of materials. This is currently attracting much interest in various sectors andtheir industrial applications at the nanoscale level will have to expand quickly in response to the transition
to a bio-based economy. The self-assembly of carbohydrate BCP systems1-4 at the nanoscale level via thebottom-up approach, has allowed the conception of nanostructured thin films and nanoparticles (micelles,vesicles,…) whose external shell is made from carbohydrates. We will present recent results on the selfassemblies of carbohydrate-based block copolymer leading to nanoparticles presenting different shapes(spherical, cubic, …), highly nanostructured thin films for nanobioelectronic applications and more recently
brush-like glycopolymers exhibiting photonic crystals behavior leading to colored materials.5

1.

Y. Liao, W.C. Chen & R. Borsali
Carbohydrate-Based Block Copolymer Thin Films: Ultrafast Nano-Organization with 7 nm Resolution
Using Microwave Adv. Mater., 1701645, Doi: 10.1002/adma.201701645, 2017, 1-62. Y.C. Chiu, H.S. Sun, Wen-Ya Lee, R. Borsali & W.C. Chen
Oligosaccharide Carbohydrate Dielectrics High-Performance Non-Volatile Transistor Memory
Devices, Adv. Mater., 27(40), Doi: 10.1002/Adma.201502088, 2015, 6257-6264
3. J.D. Cushen, I. Otsuka, C.M. Bates, S. Halila, S. Fort, J.A. Easley, E. Rausch, A. Thio, R. Borsali, C.G.
Willson & C.J. Ellison, Oligosaccharide/Silicon-Containing Block Copolymers - 5 Nm Features for
Lithographic Applications », ACS NANO, 6(4), 2012, 3424-3433
4. Hong Li, Muhammad Mumtaz, Takuya Isono, Toshifumi Satoh, Wen-Chang Chen, Redouane Borsali, Selfassembly of carbohydrate-based block copolymer systems: glyconanoparticles and highly nanostructured
thin films, Polymer Journal 2022, 54, 455-464, DOI: doi.org/10.1038/s41428-021-00604-w.
5. H. Li, M. Mumtaz and R. Borsali (manuscript in preparation).

REDOUANE BORSALICNRS RESEARCH DIRECTOR
GRENOBLE ALPES UNIVERSITYCERMAV, CNRS, GRENOBLE
borsali@cermav.cnrs.frooo

SELF-ASSEMBLY OF GLYCOPOLMER GROUP LEADERDIRECTOR OF POLYNAT CARNOT INSTITUTE, GRENOBLE, FRANCE
CO-DIRECTOR OF IRP-CNRS-UGA-NTU “GREEN MATERIAL INTITUTE”
TAIPEI, TAIWAN

Before his actual position, he served as the Director of CERMAV (Grenoble) and the group leader ofpolymer physico-chemistry group at Bordeaux (LCPO). He earned his PhD in polymer sciences at Louis
Pasteur University at Strasbourg and spent a post-doctoral position at the Max-Planck-Institute in Mainz,
Germany. He also was a visiting Professor at Stanford University, California, USA & and Visiting Scientist
at IBM, Almaden, CA, USAExpertise: Self-assemblies of Carbohydrate-based block copolymers (BCP) systems, leading to:• Nanostructured Thin films: highlight of properties/applications in nano-electronics including:(smart surfaces, nanolithography, photovoltaic, memory transistors, HR-biosensors, etc.…),Directed Self-Assembly (DSA)• Nanoparticles (micelles) & Polymersomes & their properties/applications in cosmetic/biomedical1