The 44th NIPS International Symposium
The 5th Asian Pain Symposium

Asian Pain Symposium 2013
Asian Pain Symposium 2013

December 18th‐20th,2013
Okazaki Conference Center(OCC)
Okazaki, Aichi, Japan

Oral Session
December 18 (Wed)Session1Chair; Koichi NOGUCHI (Hyogo College of Medicine)S1-1 13:00-13:25
Takayuki NAKAGAWA (Department of Molecular Pharmacology, Graduate School of
Pharmaceutical Sciences, Kyoto University, Japan)
Roles of TRPA1 in Oxaliplatin-Induced Acute Peripheral Neuropathy
S1-2

13:25-13:50
Kazue MIZUMURA (Department of Physical Therapy, College of Life and Health Sciences,Chubu University, Japan)
Muscle Pain and Neurotrophic Factors

S1-3

13:50-14:25
Lan BAO (Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences,
Chinese Academy of Sciences, China)
The trafficking regulation of Nav1.8 in primary sensory neurons

Session2
Kazue MIZUMURA (Chubu University)
S2-1 14:45-15:10
Seiji ITO (Kansai Medical University, Japan)
Bifurcate roles of nitric oxide in neuropathic pain
S2-2

15:10-15:35
Koichi NOGUCHI (Hyogo College of Medicine, Department of Anatomy and Neuroscience,Japan)
Pronociceptive Lipid Mediators In Spinal Cord In Neuropathic Pain

S2-3

15:35-16:10
Seog Bae OH (Department of Neurobiology and Physiology, Seoul National University School ofDentistry, Korea)
Chronic Pain as an Intractable Neuroinflammatory Disease

Session3
Seiji ITO (Kansai Medical University)
S3-1 16:30-16:55
Makoto TOMINAGA (Okazaki Institute for Integrative Bioscience, Japan)
Molecular mechanisms of nociception through TRPA1 activation
S3-2

16:55-17:30
Xu ZHANG (Institute of Neuroscience and State Key Laboratory of Neuroscience, Shanghai
Institutes for Biological Sciences, Chinese Academy of Sciences, China)
Role of FXYD2, γ subunit of Na+,K+-ATPase, in inflammatory pain

December 19(Thu)
Session4
Makoto TOMINAGA (Okazaki Institute for Integrative Bioscience)S4-1 9:00-9:25
Junichi NABEKURA (National Institute for Physiological Sciences, Japan)
Remodeling of Synapses in Mouse Somatosensory Cortex in Chronic Pain
S4-2

9:25-10:00
Min ZHUO (University of Toronto, Canada)
Presynaptic form of long-term potentiation in the anterior cingulate cortex mediates
injury-related anxieity

Session5
Fusao KATO (Jukei University School of Medicine)S5-1 10:20-10:45
Yasushi KURAISHI (Graduate School of Medicine and Pharmaceutical Sciences, University ofToyama, Japan)
Involvement of Oxidative Stress in Herpes-Associated Acute Pain and Itch in Mice
S5-2

10:45-11:10
Emiko SENBA (Department of Anatomy & Neurobiology, Wakayama Medical University, Japan)
Exercise training attenuates neuropathic pain by modulating microglial activation

S5-3

11:10-11:45
Bai Chuang SHYU (Institute of Biomedical Sciences, Academia Sinica, Taiwan)
Differential mechanisms of P2X7 and BDNF in central post-stroke pain

Session6
Emiko SENBA (Wakayama Medical University)
S6-1 13:15-13:40
Makoto TSUDA (Department of Molecular and System Pharmacology,Graduate School ofPharmaceutical Sciences, Kyushu University, Japan)
Microglial transcription factors and neuropathic pain
S6-2

13:40-14:15
Yong-Jing GAO (Institute of Nautical Medicine, Nantong University, China)
Chemokine-mediated astroglial-neuronal interaction in neuropathic pain

S6-3

14:15-14:40
Hiroshi UEDA (Department of Molecular Pharmacology and Neuroscience, Nagasaki University,Japan)
Roles of amplification of LPA synthesis through microglial activation in neuropathic pain

Session7
Hiroshi UEDA (Nagasaki University)
S7-1 15:00-15:25
Masabumi MINAMI (Hokaido University, Japan)
Role of the Bed Nucleus of the Stria Terminalis in Pain-induced Aversion
S7-2

15:25-16:00
Xian-Guo LIU (Pain Research Center of Sun Yat-sen University, China)
Cytokine microenvironment hypothesis of chronic painSession8
Masabumi MINAMI (Hokaido University)
S8-1 16:20-16:45
Ryusuke KAKIGI (National Institute for Physiological Sciences, Japan)
Pain and Itch Perception in Humans
S8-2

16:45-17:20
Wei-Zen SUN (National Taiwan University Hospital, Taiwan)
Awake or asleep? Behavioral correlates of the brain metabolic activity and functional
connectivity by pregabalin, alpha-2-delta antagonist, in awake neuropathic pain model

December 20 (Fri)

Session9
Yasushi KURAISHI (Toyama University)
S9-1 9:30-9:55
Hidemasa FURUE (National Institute for Physiological Sciences, Japan)
Spinal GABAergic Excitation by Optogenetic Activation of Descending Noradrenergic
System
S9-2

9:55-10:20
Guang-Yin XU (Institute of Neuroscience, Soochow University, China)
Epigenetic regulations of chronic visceral pain in functional gastrointestinal disorders

Session10
Hidemasa FURUE (National Institute for Physiological Sciences)S10-1 10:40-11:05
Fusao KATO (Department of Neuroscience,Jikei University School of Medicine, Japan)
Nociceptive Amygdala in Various Chronic Pain Models
S10-2 11:05-11:40
Jun CHEN (Fourth Military Medical University, China)
Painful neuropathy and the environment - Prediabetes and Metabolic syndrome, risks of a‘western lifestyle’Poster Session
P1Yiming ZHOU (National Institute for Physiological Sciences, Japan)
Identification of a splice variant of mouse TRPA1 that regulates TRPA1 activity

P2

Masayuki TAKAISHI (Mandom corp., Technical Development Center, Japan)
1,8-cineole, a TRPM8 agonist, is a novel natural antagonist of human TRPA1P3

Meng ZHAO (Graduate School of Pharmaceutical Sciences, Kyoto University, Japan)
Mechanism of TRPA1 activation in oxaliplatin-induced acute peripheral neuropathy

P4

Kimiaki KATANOSAKA (Research Institute of Environmental Medicine, Japan)
TRPV1- and V2-negative Heat-sensitive Primary Afferent Neurons in Mouse Dorsal
Root Ganglia

P5

Shinya KASAI (Tokyo Metropolitan Institute of Medical Science, Japan)
Reduced Supraspinal Nociceptive Responses and Distinct Gene Expression Profile in
CXBH Recombinant Inbred Mice

P6

Noboru IWAGAKI (University of Glasgow, UK)
Physiological and Morphological Characterisation of PrP-GFP Inhibitory Interneurons inthe Superficial Dorsal Horn of Young Adult MiceP7Toshiharu YASAKA (Saga University, Japan)
Excitatory and inhibitory spinal lamina II interneurons that receive inputs from putative
low-threshold mechanoreceptors in adult rats

P8Eiichi KUMAMOTO (Saga University, Japan)
Vanilloid Zingerone Enhances Spontaneous Excitatory Transmission by Activating TRPA1
but not TRPV1 Channels in the Adult Rat Substantia Gelatinosa

P9Qing-Tian LUO (Saga University, Japan)
Carvacrol Enhances Spontaneous Excitatory Transmission and Produces Outward Current
in Adult Rat Superficial Dorsal Horn Neurons

P10 Keisuke KOGA (National Institute for Physiological Sciences, Japan)
Presynaptic P2X3 receptor activates GABAergic inhibitory interneurons in Substantia
Geratinosa of rat spinal dorsal horn

P11 Koki IWASA (University of Fukui, Japan)
Contribution of zinc to the pain-induced ERK phosphorylation and neuronal plasticity inthe spinal dorsal horn
P12 Daisuke UTA (National Institute for Physiological Sciences, Japan)
Firing pattern and morphological analysis of substantia gelatinosa neurons receiving
TRPA1-expressing afferents in adult rat spinal dorsal horn.
P13 Shun WATANABE (Kitasato University, Japan)
The roles of glycosphingolipids on regulation of peripheral glutamate levels duringnociception.
P14 Ichiro OKAYASU (Nagasaki University, Japan)
Evaluation for tactile sensory and pain thresholds in the face, tongue, hand and finger ofsymptom-free subjects
P15 Kanako SO (Kyoto University, Graduate School of Pharmaceutical Sciences, Japan)
Redox-sensitive TRPA1 is involved in dysesthesia induced by transient hindlimb
ischemia-reperfusion in mice
P16 Hiroki OTA (Teikyo University, Faculty of Medical Technology, Japan)
Contribution of TRPV1 and TRPV4 in Delayed Onset Muscle Soreness
P17 Teruaki NASU (Mejiro University, Japan)
Analgesic Effect of Intramuscular Injected Neurotropin (NTP) in Repeated Cold Stressmodel
P18 Shiori MURASE (Chubu University, Japan)
A synergetic effect of nerve growth factor (NGF) and glial cell line-derived neurotrophicfactor (GDNF) in inducing muscular mechanical hyperalgesia in rats
P19 Koei HAYASHI (Nagoya University, Japan)
Muscular Mechanical Hyperalgesia Occurs in a Stretch Speed-Dependent Manner after
Lengthening Contraction in Rats
P20 Hiroshi IKEDA (University of Fukui, Japan)
Involvement of astrocytes in the long-term facilitation of neuronal excitation in the anterior
cingulate cortex of mice with inflammatory pain
P21 Miho SEKIGUCHI (Fukushima Medical University School of Medicine, Japan)
The Effect of Non-Noxious Stimulation in Pain-Related Behavior Compared with
Repeated Restraint Stress in an Experimental Nucleus Pulposus Applied Rat Model
P22 Yuka KOBAYASHI (Wakayama Medical University, Japan)
Interaction between macrophage inflammatory proteins and matrix metalloprotease 12 inmacrophage is involved in neuropathic pain.
P23 Norikazu KIGUCHI (Wakayama Medical University, Japan)
Histone H3 acetylations enhances chemokine expression leading to neuropathic painP24 Nozomi AKIMOTO (National Institute for Physiological Sciences, Japan)
Effect of Chemokine (C-C motif) ligand 1 on Synaptic Transmission in the Spinal Dorsal
Horn
P25 Yasufumi HAYANO (Graduate School of Medicine, Osaka University, Japan)
Netrin Acts As a Pain-Inducing Factor in Adult Spinal Cord
P26 Koichi ISAMI (Kyoto University, Graduate School of Pharmaceutical Sciences, Japan)
Peripheral nerve injury-induced infiltration of bone marrow-derived cells into the spinal
cord in neuropathic pain: roles of TRPM2
P27 Kiyomi HORI (Kanazawa University Graduate School of Medical Science, Japan)
P2X3,2/3 and ASICs contribute to muscle hyperalgesia and intermittent claudication in a
new rat model of peripheral arterial disease.
P28 Koji DOGISHI (Graduate School of pharmaceutical sciences, Kyoto University, Japan)
Behaviors associated with pain in mice model of chronic inflammatory and overactive
bladder by intravesical injection of hydrogen peroxide
P29 Nguyen Huu Tu (Department of Medical Chemistry, Kansai Medical University, Japan)
Energy coupling of axon-Schwann cells by Nax and endothelin in nerve regeneration
P30 Tsutomu HAYASHI (Graduate School of Engineering, University of Fukui, Japan)
Involvement of Extracellular Signal-Regulated Kinase and NMDA receptor in the Anterior
Cingulate Cortex to the affective component and hypersensitivity of pain
P31 Syuntaro TAKASU (Graduate School of Engineering, University of Fukui, Japan)
Contribution of the descending pain inhibitory system to the analgesic effect by smellingthe aroma oil