Mizuno Research Fund Post-Doctoral Fellowship Program for Japanese Researcher
Children’s Hospital of Philadelphiain Collaboration with the Noguchi Medical Research InstituteInvitation for Japanese Research Post-doctoral Fellowship in Benign Hematology
GOAL:
To provide for 1-2 years of support, starting from January 1, 2018, to a Japanese scientist interested ina research training opportunity in benign hematology under the guidance of a member of the Division ofHematology at Children’s Hospital of Philadelphia.
OPPORTUNITY:
The Mizuno Research Fund will support a Japanese scholar in collaboration with the Noguchi MedicalResearch Institute. Funding level is $50,000 per year plus $5,000 travel allowance with up to two yearsof support. Note, funds can be combined with other means of support. Will be paid on a monthly basis.
Children’s Hospital of Philadelphia is one of the premier pediatric Institutions international and theDivision of Hematology carries out outstanding research in the following areas:• clotting and thrombosis• bone marrow development• bone marrow failure• red cell biology• megakaryocyte and platelet development
Please see the second page of this announcement for more details.
CANDIDATE:
1. Hold an M.D., Ph.D., M.D./Ph.D. or equivalent degree(s).
2. Is a post-doctoral, an instructor or is in the first three years of faculty position.
3. Japanese individual who is able to communicate well both in writing and speaking in English.
4. Prior related research experience, and
5. Able to be in the United States for the anticipated 1-2 years of support with appropriate visa.
6. Obtained Institutional permission to come for this training.
APPLICATION PROCESS:
Please forward the following before July 31, 2017:
1. Application form.
2. A cover letter including research experience of the candidate and future academic goals.
3. The candidate's curriculum vitae in English and Japanese.
4. A letter of reference/recommendation from the candidate's current/previous mentor or supervisor inJapan with a description of the candidate’s potential for future academic success, past training andfuture academic opportunities back in Japan.
5. Screening：By documents and interview.
6. Please send to the application to：〒105-0001＜問い合わせ＞

東京都港区虎ノ門1-22-13秋山ビル5F

医学教育＆交流担当

米国財団法人野口医学研究所

杉田恭子 / ステロラ・スンヨビ

医学教育＆交流室 担当者宛

E-Mail：ryugaku@noguchi-net.com※封筒に『Japanese Research Fellow 応募書類在中』と記載すること。

電話：03-3501-0130

List of areas of research available with examples of potential projects.
Coagulation• Crystallographic and functional of coagulation factors• Structure/function of coagulation Factor X:Clinical application• Structure/function of coagulation Factor V:Clinical application• Coagulation factor VIII and IX biology• Structural and functional studies of factor VIII increased specific activity mutations and their clinicalapplication• Immunomodulation of patients with hemophilia A and inhibitors• Structure/function of thrombomodulin/thrombin• Biology of FVII and its clinical application• Studies of a rat model of hemophilia
Thrombosis• Spatial/temporal distribution of components in hemostasis/thrombosis• Studies of the prothrombotic nature of HIT (heparin-induced thrombocytopenia)• The biologic basis of thrombosis in immunothrombosis including HIT• Platelet factor 4 in sepsis and NETosis
Hematopoiesis/stem cell biology• Epigenetic modulation of hematopoietic stem cells• Lnk/STAT biology in hematopoiesis• Role of ubiquitination in hematopoiesis
Red blood cells and the hemoglobinopathies• Novel gene therapy for sickle cell disease, including chromatin looping and altering Bcl11biology
in red cells• Biology of transcriptional factor GATA1 short• Lentiviral gene therapy for the hemoglobinopathies• Iron metabolism and hepcidin• Macrophages and inflammation
Megakaryocyte biology and platelet production• Megakaryopoiesis and its clinical application including targeted-drug delivery• Pulmonary in vivo thrombopoiesis
Blood banking• Blood banking related to molecular polymorphisms in the Rh locus
Bone marrow failure• Evolution of spontaneous clones in acquired aplastic anemia• Niche biology in hematopoiesis post chemo-radiotherapy