Listening to the science on BPA from Austria
BY STEVEN HENTGES, PH.D ON DECEMBER 6, 2016 IN INDUSTRY, POLICY

If you live in Austria, should you be concerned about exposure to bisphenol A (BPA)? Not
according to the results of a new study from Austrian government researchers that was justpublished in the peer-reviewed scientific literature.
The title of the new study (Human biomonitoring of bisphenol A exposure in an Austrian
population) may not sound so interesting, but the results are very important. Biomonitoringrefers to a scientific technique for measuring exposure to chemicals by measuring theirlevels in biological samples, such as urine or blood. The results of biomonitoring studies
provide critical information to evaluate whether exposure to a chemical is safe or not.
What the Austrian researchers did was measure the level of BPA in urine samples from alarge group of Austrians, ranging in age from 6-81 years. Measuring BPA in urine isconsidered the most scientifically reliable way to evaluate exposure because BPA is quickly
eliminated from the body in urine after exposure. In other words, what goes in (i.e.,exposure) comes out in urine where it’s easy to measure.
If you’re interested in safety though, measuring exposure is only half of the safetyequation. How do we know what the data means? What levels are safe and, more
importantly, what levels are unsafe? Fortunately there’s quite a bit of information on theother half of the equation that readily allows us to interpret biomonitoring data in the contextof safety.
Of particular value for interpreting biomonitoring data, a group of researchers in
Greece reported a “biomonitoring equivalent” (BE) value for BPA in another recentstudy. The BE value is based on the conservative safe intake level recently established for
BPA by the European Food Safety Authority, and the BE value represents the estimatedconcentration of BPA in urine corresponding to intake of BPA at the safe intake level.
The median BPA level measured in the Austrian study population is more than 250 times
below the BE level. This indicates that the actual Austrian exposure levels are not only
safe, but they’re safe with a wide margin of safety. So if you do live in Austria, there’s noneed to be concerned about exposure to BPA.
But what if you don’t live in Austria? As it turns out, the Austrian researchers aren’t the
only ones who have conducted biomonitoring studies on BPA. Large-scale studies fromseveral other countries report BPA levels in urine that are similar to the levels found in theAustrian population.

For example, recent studies on pregnant women in France and Canada confirmed low
exposure levels that are particularly noteworthy, since pregnant women might generally beconsidered one of the most vulnerable subpopulations for exposure tochemicals. Similarly, the results from large-scale biomonitoring studies on the general
populations of the United States and Canada further demonstrate low BPA exposure levels.
Government bodies around the world support the safety of BPA based on their review ofextensive scientific information, including biomonitoring data that consistently demonstrates
very low exposure. For example, the U.S. Food and Drug Administration answers thequestion “Is BPA safe?” with a crystal clear answer – “Yes.”