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Home Roomї p.30

Hospital Practiceї p.36

Laboratory Practice
CourseMedical Technology
Special Lectureї p.36
ї p.137
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༤ኈㄢ⛬ᩍ⫱࣮ࣜࢹ࢕ࣥࢢࣉࣟࢢ࣒ࣛබເせ㡿㸦20122ࠊᩥ㒊⛉Ꮫ┬㸧࠿ࡽ  ࠕ༤ኈㄢ⛬ᩍ⫱࣮ࣜࢹ࢕ࣥࢢࣉࣟࢢ࣒ࣛࠖࡣࠊඃ⚽࡞Ꮫ⏕ࢆಠ▔ຊ࡜⊂๰ຊࢆഛ࠼ᗈࡃ⏘Ꮫᐁ࡟ࢃࡓࡾ
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㸦㸱㸧 ༤ኈㄢ⛬ᩍ⫱࣮ࣜࢹ࢕ࣥࢢࣉࣟࢢ࣒ࣛ࡟ಀࡿ࣒࣭࣏࢝ࣜ࢟ࣗࣛࣜࢩ࣮ ᅜෆእࡢ」ᩘࡢᩍဨ࣭ᣦᑟ⪅࡜ࡢᑐヰࢆ㏻ࡌࡓⓎᒎⓗ⮬Ꮫ⮬⩦ࡸ⏘ᐁᏛࡢཧ⏬࡟ࡼࡿேᮦ㣴ᡂࢆ௓ࡋ࡚ࠊ◊✲௻⏬ࡢ᥎㐍ຊ࡜♫఍࡬ࡢㄝ᫂ຊࠊ◊✲ࢳ࣮࣒ࢆ⤌⧊ࡋ᪂ࡋ࠸◊✲ศ㔝ࢆᅜ㝿ⓗ࡟ඛᑟࡍࡿ⬟ຊࢆࡶࡗ࡚ከᵝ࡞ᑓ㛛ศ㔝ࢆಠ▔ࡋࠊ๰㐀ⓗ࡟ㄢ㢟ゎỴ࡟࠶ࡓࡿࡓࡵ࡟ᚲせ࡞⬟ຊࢆ⫱ࡴୡ⏺࡟㏻⏝ࡍࡿ࣒࢝ࣜ࢟ࣗࣛࢆ⦅ᡂ࣭ᐇ᪋ࡍࡿࠋ ༤ኈㄽᩥ◊✲ᇶ♏ຊᑂᰝࡲ࡛ࡢᏛಟᮇ㛫࡟࠾࠸࡚ࡣࠊ㉁ࡢಖドࡉࢀࡓከᵝ࡞ᑓ㛛ᩍ⫱࡟ࡼࡗ࡚ᙜヱࣉࣟࢢ࣒ࣛ࡟㛵ࡍࡿᖜᗈ࠸▱㆑ࢆಟᚓࡉࡏࡿ࡜࡜ࡶ࡟ࠊ」ᩘࡢᩍဨ࡟ࡼࡿ◊✲ᣦᑟࢆ㏻ࡌ࡚ᑓ㛛ศ㔝ࢆ⥲ྜⓗ࡟⌮ゎࡉࡏࡿ࣒࢝ࣜ࢟ࣗࣛࢆ⦅ᡂ࣭ᐇ᪋ࡍࡿࠋࡲࡓࠊ⏘ᐁᏛࡢ༠ാ࡟ࡼࡿᐇ㊶ⓗᩍ⫱࡞࡝ࢆ௓ࡋ࡚ࠊࢥ࣑ࣗࢽࢣ࣮ࢩࣙࣥຊࠊ◊✲࣭㛤Ⓨࡢィ⏬ຊ࡜᥎㐍ຊࠊ⮬ࡽㄢ㢟ࢆⓎぢࡍࡿ⬟ຊ࡞࡝ࢆ㌟࡟ࡘࡅࡉࡏࡿࠋ ࣒࣭࣏࢝ࣜ࢟ࣗࣛࣜࢩ࣮ࡢヲ⣽ࡣᙜヱࣉࣟࢢ࣒ࣛ࡟࠾࠸࡚ᐃࡵࡿࠋ

㸦㸲㸧༤ኈㄢ⛬ᩍ⫱࣮ࣜࢹ࢕ࣥࢢࣉࣟࢢ࣒ࣛ࡟ಀࡿࢹ࢕ࣉ࣐࣭࣏ࣟࣜࢩ࣮ ᚋᮇㄢ⛬࡟࠾࠸࡚ࡣࠊᙜヱ◊✲⛉ࡢᐃࡵࡿᮇ㛫ᅾᏛࡋ࡚ࠊ◊✲⛉➼ࡀᐇ᪋ࡍࡿ༤ኈㄢ⛬ᩍ⫱࣮ࣜࢹ࢕ࣥࢢࣉࣟࢢ࣒ࣛࡢ࣒࣭࣏࢝ࣜ࢟ࣗࣛࣜࢩ࣮࡟ἢࡗࡓ◊✲ᣦᑟࢆཷࡅࠊᙜヱࣉࣟࢢ࣒ࣛࢆಟ஢ࡍࡿ࡜࡜ࡶ࡟ࠊᡤᐃᖺ㝈ෆ࡟ᥦฟࡋࡓ༤ኈㄽᩥ࡟ࡘ࠸࡚◊✲⛉ࡀ⾜࠺ᑂᰝ࡜ヨ㦂࡟ྜ᱁ࡋࠊᚋᮇㄢ⛬ࢆಟ஢ࡍࡿࡇ࡜ࡀ༤ኈࡢᏛ఩ᤵ୚ࡢせ௳࡛࠶ࡿࠋ◊✲⛉࡟ࡼࡗ࡚ࡣࠊᡤᐃࡢᤵᴗ⛉┠ࢆᒚಟࡋ࡚ࠊᇶ‽࡜࡞ࡿ༢఩ᩘ௨ୖࢆಟᚓࡍࡿࡇ࡜ࢆせ௳࡟ྵࡴሙྜࡀ࠶ࡿࠋ ከᵝ࡞ᑓ㛛ศ㔝ࢆಠ▔ࡋࠊ๰㐀ⓗ࡟ㄢ㢟ゎỴ࡟࠶ࡓࡿࡓࡵ࡟ᚲせ࡞⬟ຊ࡜ࡑࡢᇶ┙࡜࡞
ࡿᏛ㆑ࢆ㌟࡟ࡘࡅ࡚࠸ࡿ࠿࡝࠺࠿ࠊ࠾ࡼࡧࠊࢢ࣮ࣟࣂࣝ࡟ά㌍ࡍࡿࡓࡵ࡟ᚲせ࡞ࢥ࣑ࣗࢽ
ࢣ࣮ࢩࣙࣥຊ࡜ᅜ㝿ᛶࢆ⵳࠼࡚࠸ࡿ࠿࡝࠺࠿ࡀࠊᙜヱࣉࣟࢢ࣒ࣛಟ஢ࡢᇶ‽࡛࠶ࡿࠋ ๓ᮇㄢ⛬࡟࠾࠸࡚ಟኈࡢᏛ఩ࢆᤵ୚ࡍࡿ◊✲⛉࡟࠶ࡗ࡚ࡣࠊ◊✲⛉➼ࡀᐇ᪋ࡍࡿ༤ኈㄢ
⛬ᩍ⫱࣮ࣜࢹ࢕ࣥࢢࣉࣟࢢ࣒ࣛࡢ࣒࣭࣏࢝ࣜ࢟ࣗࣛࣜࢩ࣮࡟ἢࡗ࡚タィࡉࢀࡓᤵᴗ⛉┠ࢆᒚಟࡋ࡚ࠊᇶ‽࡜࡞ࡿ༢఩ᩘ௨ୖࢆಟᚓࡋࠊᙜヱࣉࣟࢢ࣒ࣛࡀᐃࡵࡿ༤ኈㄽᩥ◊✲ᇶ♏ຊᑂᰝ࡟ྜ᱁ࡍࡿ࡜࡜ࡶ࡟ࠊᡤᐃᖺ㝈ෆ࡟ᥦฟࡋࡓಟኈㄽᩥ࡟ࡘ࠸࡚ࠊ◊✲⛉ࡀ⾜࠺ᑂᰝ࡜ヨ㦂࡟ྜ᱁ࡋࠊ๓ᮇㄢ⛬ࢆಟ஢ࡍࡿࡇ࡜ࡀಟኈࡢᏛ఩ᤵ୚ࡢせ௳࡛࠶ࡿࠋ ༤ኈㄽᩥ◊✲ᇶ♏ຊᑂᰝ࡟ྜ᱁ࡍࡿ࡟ࡣࠊᙜヱࣉࣟࢢ࣒ࣛࡢ┠ⓗ࡟ἢࡗ࡚タᐃࡋࡓᤵᴗ
⛉┠ࢆᒚಟࡋ࡚ࠊᇶ‽࡜࡞ࡿ༢఩ᩘ௨ୖࢆಟᚓࡍࡿ࡜࡜ࡶ࡟ࠊࣉࣟࢢ࣒ࣛࡢᐃࡵࡿࡑࡢ௚ࡢせ௳ࢆ‶ࡓࡍᚲせࡀ࠶ࡿࠋ ༤ኈㄽᩥసᡂ࡟ᚲせ࡞◊✲ᇶ♏ຊ࡛࠶ࡿᑓ㛛ᇶ♏▱㆑ࠊᖜᗈࡃ῝࠸▱㆑ࠊ◊✲ィ⏬ຊࠊㄒᏛຊࢆᇶ♏࡜ࡍࡿࢥ࣑ࣗࢽࢣ࣮ࢩࣙࣥຊ࡞࡝ࢆഛ࠼࡚࠸ࡿ࠿࡝࠺࠿ࡀࠊ༤ኈㄽᩥ◊✲ᇶ♏ຊᑂᰝྜ᱁ࡢᇶ‽࡛࠶ࡿࠋ ◊✲⛉ࡀ⾜࠺༤ኈㄽᩥཬࡧಟኈㄽᩥࡢᑂᰝᇶ‽࡟ࡘ࠸࡚ࡣᙜヱ◊✲⛉ࡢࢹ࢕ࣉ࣐࣭࣏ࣟ
ࣜࢩ࣮ࢆཧ↷ࡍࡿࡇ࡜ࠋ

㸰 ඘ᐇࡋࡓ೺ᗣ㛗ᑑ♫఍ࢆ⠏ࡃ⥲ྜ་⒪㛤Ⓨ࣮ࣜࢲ࣮⫱ᡂࣉࣟࢢ࣒ࣛ
ୡ⏺ⓗ࡟ேཱྀࡢ㧗㱋໬ࡀᗈࡀࡿ୰ࠊୡ⏺᭱㛗ࡢ೺ᗣᑑ࿨࡜ඛ➃ⓗ◊✲㛤Ⓨ⬟ຊ࡜࠸࠺᮲௳ࢆ
ྜࢃࡏᣢࡘ᪥ᮏ࡛ࡣࠊ㧗㱋໬♫఍ࡢၥ㢟ࢆಠ▔ࡋࠊ࣓ࢹ࢕࢝ࣝ࢖ࣀ࣮࣋ࢩࣙࣥࢆ㏻ࡌ࡚඘ᐇࡋ
ࡓ೺ᗣ㛗ᑑ♫఍ࢆ㐩ᡂࡍࡿேᮦࢆࠊୡ⏺࡟㍮ฟࡍࡿࡇ࡜ࡀᛴົ࡜࡞ࡗ࡚࠸ࡿࠋࡑࡇ࡛ᮏࣉࣟࢢ
࣒࡛ࣛࡣࠊ㧗㱋໬♫఍ࡀᢪ࠼ࡿၥ㢟ࢆಠ▔ࡋࠊϨᕤᏛᢏ⾡ࢆ་⒪࣭ᨭ᥼ࢩࢫࢸ࣒࡬㐺⏝ࡋࠊϩ་Ꮫࡢ୰࡟⵳࠼ࡽࢀࡓ▱㆑ࢆᕤᏛ࡟ά⏝ࡍࡿ࡜࠸࠺㸰᪉ྥ࠿ࡽࠊලయⓗ࡞ゎỴἲࢆ๰᱌ࡋࠊ
඘ᐇࡋࡓ೺ᗣ㛗ᑑ♫఍ࡢᵓ⠏࡟ྥࡅ᥎㐍ࡍࡿࡇ࡜ࡢฟ᮶ࡿࠕ⥲ྜ་⒪㛤Ⓨ࣮ࣜࢲ࣮ࠖࢆࠊ␗ศ
㔝ࡢ◊✲⪅ࢆ⤌ࡳྜࢃࡏࡓ⏘Ꮫᶓ᩿ⓗ࡞ᩍ⫱ࣉࣟࢢ࣒ࣛ࡟࠾࠸࡚⤌⧊ⓗ࡟⫱ᡂࡍࡿࠋ
Ϩ┿࡟་Ꮫ࣭་⒪ࡀศ࠿ࡿ་ᕤᏛேᮦ
ᮏࣉࣟࢢ࣒࡛ࣛࡣࠊᕤᏛ⣔ࡢࣉࣟࢢ࣒ࣛᒚಟ⪅࡟ேయゎ๗Ꮫࠊ⏕⌮Ꮫࠊ⑓⌮Ꮫ࡞࡝ࡢᇶ♏་Ꮫᩍ⫱࡜⑓㝔ෆᐇ⩦ࢆㄢࡋࠊ」ᩘศ㔝ࡢᩍဨ࡟ࡼࡿ⥥ᐦ࡞ウㄽ࣭ᣦᑟࢆ⾜࠸ࠊ་Ꮫ㒊༞ᴗ⏕࡜ྠ➼ࡢ་Ꮫ࣭་⒪▱㆑ࢆ᭷ࡍࡿ་ᕤᏛேᮦࢆ⫱ᡂࡍࡿࠋ་⒪࣭ᨭ᥼⌧ሙࡢᐇ⩦ࡸ་⒪೔⌮Ꮫࢆ㏻ࡌࠊ฼⏝⪅࡟࡜ࡾ㈇ᢸࡢᑡ࡞࠸ࠕ㧗㱋⪅࡟ඃࡋ࠸ࠖᶵჾ࣭ࢩࢫࢸ࣒ࢆ㛤Ⓨࡍࡿࢭࣥࢫࢆᾰ㣴ࡍࡿࠋ་⒪⌧ሙࡢࢽ࣮ࢬࡸ་⒪⤒῭Ꮫ࣭チㄆྍไᗘࡢ▱㆑࡟ᇶ࡙ࡁࠊᶵჾ࣭ࢩࢫࢸ࣒ࡢ⏘ᴗ໬࣭ᕷሙࡢண ⬟ຊࢆ㣴࠺ࠋᅜ㝿ᶆ‽໬ࡢ▱㆑ࡸ༟㉺ࡋࡓࢥ࣑ࣗࢽࢣ࣮ࢩࣙࣥ⬟ຊࢆഛ࠼ࠊᅜ㝿ᶆ‽໬ᶵᵓ࡞࡝࡛ά㌍࡛ࡁࡿேᮦࢆ⫱ᡂࡍࡿࠋ
ϩ་Ꮫࡢ୰࡟⵳࠼ࡽࢀࡓ▱㆑ࢆከศ㔝࡟Ⓨᒎࡉࡏࡿ࣮ࣜࢲ࣮
ୡ⏺ࡢ௚ᆅᇦ࡟ඛ㥑ࡅ࡚㧗㱋໬♫఍ࢆ㏄࠼ࡿ᪥ᮏ࡛ࠊ೺ᗣᑑ࿨ࡀୡ⏺᭱㛗࡛࠶ࡿ࡜࠸࠺⫼ᬒࢆά࠿ࡋࠊ㧗㱋⪅ࡀ⮬❧ࡋ࡚♫఍ཧຍࡍࡿࡢ࡟㐺ࡋࡓ♫఍ࢩࢫࢸ࣒ࡸ᪂⏘ᴗࢆ๰ฟ࡛ࡁࡿேᮦ
ࢆ⫱ᡂࡍࡿࠋ᭦࡟ࠊࡇࡢ͆᪥ᮏࣔࢹ͇ࣝࢆඛ㐩࡜ࡋ࡚ୡ⏺ࡢ೺ᗣ㛗ᑑྥୖࢆ≌ᘬ࡛ࡁࡿேᮦࢆ
⫱ᡂࡍࡿࠋ
ࡇࢀࡽϨཬࡧϩࡢ࣮ࣜࢲ࣮ேᮦࢆ㍮ฟࡋࠊ᪂ࡓ࡞Ꮫ㝿ⓗ◊✲㛤Ⓨࡢ᥎㐍ࢆྍ⬟࡜ࡍࡿࡇ࡜
࡟ࡼࡗ࡚ࠊ㇏࠿࡞೺ᗣ㛗ᑑ♫఍ࡢᵓ⠏࡟㈉⊩ࡍࡿࡇ࡜ࢆ┠ⓗ࡜ࡍࡿࠋ
ᮏࣉࣟࢢ࣒ࣛࡢᏛၥศ㔝ࡣࠊࠕ་ᕤᏛ࡛ࠖ࠶ࡾࠊࣉࣟࢢ࣒ࣛᒚಟ⪅ࡣࠊ་Ꮫ◊✲⛉ࠊᕤᏛ◊✲⛉ࠊ⸆Ꮫ◊✲⛉ࡢఱࢀ࠿࡟ᒓࡍࡿࡇ࡜࠿ࡽࠊᕤᏛ㒊ฟ㌟⪅ࠊࡲࡓࡣ⏕≀㛵ಀᏛ㒊ฟ㌟⪅ࡢఱࢀ࠿ࡀ᝿ᐃࡉࢀࡿࠋࡓࡔࡋࠊฟ㌟Ꮫ㒊ࢆ㝈ᐃࡍࡿࡇ࡜ࡣ࡞࠸ࠋᕤᏛ㒊ฟ㌟⪅ࡣࠊᕤᏛ⪅࡜ࡋ࡚ࡢᐇຊࢆ᭷ࡋ࠿ࡘ་Ꮫ㒊Ꮫ⏕࡜ྠ➼࡞ேయ࣭⏕≀Ꮫࡢ▱㆑ࢆ᭷ࡍࡿࡇ࡜ࠊࡲࡓ⏕≀㛵ಀᏛ㒊ࡢฟ㌟⪅࡛ࡣᕤᏛ◊✲ࡀ⾜࠼ࡿᕤᏛࡢᑓ㛛ᛶࡢ㧗࠸▱㆑ࢆྲྀᚓࡍࡿࡇ࡜ࢆ┠ᣦࡍࠋࣉࣟࢢ࣒ࣛࡣㅮ
⩏ࠊ₇⩦࣭ᐇ⩦࡜≉ู◊✲࡟ࡼࡾᵓᡂࡉࢀࡿࠋ㸱 ඘ᐇࡋࡓ೺ᗣ㛗ᑑ♫఍ࢆ⠏ࡃ⥲ྜ་⒪㛤Ⓨ࣮ࣜࢲ࣮⫱ᡂࣉࣟࢢ࣒ࣛࡢ࢔ࢻ࣑ࢵࢩ࣭ࣙࣥ
࣏ࣜࢩ࣮་ᕤ㐃ᦠ࡜࠸࠺ࡇ࡜ࡀ㔜せ࡛࠶ࡿ࡜ゝࢃࢀ࡚ஂࡋ࠸ࠋࡋ࠿ࡋࠊゝⴥࡑࡢࡶࡢࡢព࿡ࡍࡿ࡜ࡇࢁ
ࡣࠊ་Ꮫ◊✲⪅࡜ᕤᏛ◊✲⪅ࡀ༠ຊࡋྜ࠸ࠊ࠶ࡓࡽࡋ࠸་⒪ᶵჾ࡞ࡾࠊ་⒪᪉ἲࢆ㛤Ⓨࡍࡿ࡜࠸࠺࡜ࡇࢁ࡟࠶ࡾࠊࡍ࡛࡟࠶ࡿ◊✲ᡂᯝࡸၥ㢟Ⅼࢆ༠ຊࡋ࡚ゎỴࡋ࡚࠸ࡃ࡜࠸࠺ࡇ࡜࡛࠶ࡗࡓࠋ

Ṕྐࢆࡓ࡝ࡿ࡜ࠊ⬻ື⬦⒗ᡭ⾡࡛᰿἞⒪ἲ࡜࡞ࡿࢿࢵࢡࢡࣜࢵࣉࡀ࡛ࡁ࡞࠸ሙྜࠊᡭࡀ╔ࡅࡼ࠺ࡢ࡞࠸ࡶࡢࢆື⬦⒗ࡢୖ࠿ࡽ᥋╔๣࡛ฟ⾑ࡋ࡞࠸ࡼ࠺࡟ࡍࡿ࡜࠸࠺Ⓨ᝿ࢆ⬻እ⛉࠿ࡽᣢࡕࠊᕤ
Ꮫ࡜ඹྠࡋ࡚ࣅ࢜࣎ࣥࢻ࡜࠸࠺ࠊ‵Ẽࡢ࠶ࡿ⤌⧊࡛ࡶ᥋╔⬟ຊࡢ࠶ࡿ≉Ṧ࡞᥋╔๣ࢆ⪃᱌ࡋ࡚ࠊ⬻ື⬦⒗ࡢᡭ⾡ࡢᖜࢆᗈࡆࡿࡇ࡜࡟ᡂຌࡋ࡚࠸ࡿࠋ௨๓ࡣࠊᕤᏛ◊✲࡟ேయࡢᶆᮏ࡞࡝ࢆᣢࡕ㎸ࡴࡇ࡜ࡣ↓ㅛ࡟㏆࠸ヰࡋ࡛࠶ࡗࡓࡼ࠺࡛࠶ࡿࡀࠊ⌧ᅾ࡛ࡣࠊᙜ↛࡜ᛮࢃࢀ࡚࠸ࡿࡇࡢࡼ࠺࡞◊✲ᡂᯝࡶඛேࡢከࡃࡢດຊ࡟ࡼࡿࡶࡢ࡛ࠊࡋ࠿ࡶࠊ◊✲⤌⧊ࢆࡲࡓ࠸࡛ࡢ◊✲࡜࠸࠺Ⅼ࡛㔜せ࡞ࡶࡢ࡛࠶ࡿࠋᮏࣉࣟࢢ࣒࡛ࣛࡣࠊࡇࡢࡼ࠺࡞◊✲㡿ᇦࢆ㉸࠼ࡓ◊✲ࢆ⾜࠺ࡔࡅ࡛ࡣ࡞ࡃࠊ஫࠸࡟ᑓ㛛࡜ࡍࡿ◊✲㡿ᇦࢆᣢࡕࠊࡑࢀࢆࡶ࡜࡟᪂ࡋ࠸Ⓨ᝿ࢆࡍࡿࡢ࡛ࡣ࡞ࡃࠊࠕ་Ꮫ◊✲⎔ቃࡢ୰࡛ᕤᏛࢆᏛࡪࠖ
࡜࠸࠺ࡉࡽ࡟୍Ṍ㋃ࡳ㎸ࢇࡔⓎ᝿࡛ࠊᕤᏛ⣔ࡢ኱Ꮫ㝔⏕ࡢ◊✲ࡢሙࢆ་Ꮫ◊✲⛉ࡢ୰࡟࠾ࡁࠊ་
Ꮫ◊✲ࡑࡢࡶࡢࢆ⾜࠺ࡢ࡛ࡣ࡞ࡃࠊᕤᏛⓗぢᆅ࠿ࡽぢ࡚᪂ࡋࡃ་Ꮫ࡬㈉⊩ࡍࡿ࡜ࡇࢁࡀ࡞࠸࠿ࢆ
◊✲ࡍࡿ┠ⓗព㆑ࢆᣢࡕࠊᕤᏛࡢᇶ♏◊✲ࡢࢺ࣮ࣞࢽࣥࢢࢆཷࡅࡘࡘࠊ་Ꮫࡢᇶ♏࠿ࡽ⮫ᗋࠊ௓ㆤࡲ࡛ࢆᏛࡧࠊ་Ꮫ࣭ᕤᏛࡢᇉ᰿ࢆ㉺࠼ࡓ᪂ࡋ࠸◊✲㡿ᇦࢆ㛤ᣅࡋ࡚࠸ࡃࡇ࡜ࢆ┠ⓗ࡜ࡋ࡚࠸ࡿࠋ
≉࡟ࠊ㧗㱋໬ࡀ㢧ⴭ࡟㐍ࢇ࡛࠸ࡿ᪥ᮏ࡛ࠊ㧗㱋⪅་⒪࣭௓ㆤࡣ㛗࠸೺ᗣ㛗ᑑࢆ㐩ᡂࡍࡿ࡟ࡣᚲ
㡲ࡢ᮲௳ࡢ୍ࡘ࡛࠶ࡿࡀࠊ༢࡟ࠊ⑓㝔࡛⾜࠺་⒪ࡔࡅ࡛ࡣ࡞ࡃࠊ୍⯡ᐙᗞ࡟ࡶࡗ࡜ࡶ㏆࠸᥃࠿ࡾ௜ࡅ་࡬ࡢᨭ᥼ࠊ㛗ᮇ⒪㣴᪋タࡢ࠶ࡾ᪉࡞࡝ࠊ་⒪タഛࡢๅ᪂࡜࡜ࡶ࡟ࠊᕤᏛⓗᡭἲࢆࡶ࡜࡟ࡋ
࡚㧗㱋໬ࡋࡓ♫఍ࢆᨭ࠼ࡿࡓࡵࡢࡉࡲࡊࡲ࡞ᕤኵࢆ♫఍࡟ྥ࠿ࡗ࡚✚ᴟⓗ࡟Ⓨಙ࡛ࡁࡿேᮦࢆ⫱ᡂࡋ࡚ࠊ᪂ࡋ࠸་ᕤ㐃ᦠࡢጼࡀ♫఍࡟᭷ຠ࡟ᶵ⬟࡛ࡁࡿࡇ࡜ࢆ♧ࡍࡇ࡜ࢆࠊࡶ࠺୍ࡘࡢ኱ࡁ࡞┠ⓗ࡜ࡋ࡚࠸ࡿࠋ
ࡇࡢࡼ࠺࡞᪂ࡋ࠸⪃࠼᪉ࢆࡶ࡜࡟ࠊ௒ᅇࡢࣉࣟࢪ࢙ࢡࢺࡀࢫࢱ࣮ࢺࡋࠊ་Ꮫ◊✲⛉ࡀ୰ᚰ࡜࡞
ࡗ࡚ࠊᕤᏛ◊✲⛉ࡸ෌⏕་⛉Ꮫ◊✲ᡤࡢࢫࢱࢵࣇࡀ༠ຊࡋࡓయไࢆసࡾࠊୖグࡢ┠ⓗࢆ㐩ᡂࡍ࡭ࡃ࣒࢝ࣜ࢟ࣗࣛࢆᕤኵࡋ࡚࠸ࡿࠋࡇࢀࡲ࡛ࡢ኱Ꮫ㝔࡜␗࡞ࡾ࣮ࣜࢹ࢕ࣥࢢ኱Ꮫ㝔࡛ࡣ♫఍࡜ࡢ᥋Ⅼࢆ㔜どࡋࡓேᮦ⫱ᡂࢆ┠ⓗ࡜ࡋ࡚࠸ࡿࡢ࡛ࠊᗈࡃⱥㄒ࡟ࡼࡿウㄽ࣭ࢹ࢕࣮࣋ࢺ࡟ࡼࡿ⮬ศࡢព
ᛮࡢⓎಙ⬟ຊࡢ㣴ᡂ࡜ࠊ♫఍ࢆ་⒪ࡢほⅬ࠿ࡽಠ▔ࡍࡿ་⒪⤒῭Ꮫ࡞࡝ࠊ་ᕤ㐃ᦠࡔࡅ࡟࡜࡝ࡲ
ࡽ࡞࠸ᗈ࠸ୡ⏺ⓗど㔝࡟❧ࡗࡓேᮦ⫱ᡂࢆ┠ᣦࡋ࡚࠸ࡿⅬ࡛ࠊࡇࢀ࠿ࡽࡢ㧗㱋♫఍࡬㈨ࡍࡿேᮦ
ࡢ⫱ᡂ࡟ᙺ❧ࡘ࡜ಙࡎࡿࡶࡢ࡛࠶ࡿࠋ㸲 ඘ᐇࡋࡓ೺ᗣ㛗ᑑ♫఍ࢆ⠏ࡃ⥲ྜ་⒪㛤Ⓨ࣮ࣜࢲ࣮⫱ᡂࣉࣟࢢ࣒ࣛࡢ࣒࢝ࣜ࢟ࣗࣛ
㸦㸯㸧㸳ᖺ୍㈏ᩍ⫱ᮏࣉࣟࢢ࣒ࣛࡣ㸳ᖺ୍㈏ࡢ኱Ꮫ㝔ᩍ⫱ࢆ⾜࠺ࠋᮏࣉࣟࢢ࣒ࣛࡢᒚಟ⪅ࡢཷධ㐣⛬࡜ࡋ࡚ࠊඛ
ࡎᡤᒓ◊✲⛉࡜࡞ࡿᮏᏛ་Ꮫ◊✲⛉㸦་⛉Ꮫᑓᨷ࣭ே㛫೺ᗣ⛉Ꮫ⣔ᑓᨷ㸧࣭ᕤᏛ◊✲⛉࣭⸆Ꮫ◊✲⛉ࡢಟኈㄢ⛬ࡢධᏛヨ㦂ࢆཷ㦂ࡋࠊྜ᱁ࡍࡿࡇ࡜ࢆ๓ᥦ࡜ࡍࡿࠋࡓࡔࡋࠊࡇࢀࡽࡢᏛ㒊ࡸி㒔኱Ꮫࡢฟ㌟⪅࡛࠶ࡿᚲせࡣ࡞࠸ࠋ␃Ꮫ⏕ࡶ✚ᴟⓗ࡟ཷࡅධࢀࡿࠋ
♫఍ே⤒㦂⪅ࡢᒚಟࡶチྍࡍࡿࡀࠊᮏࣉࣟࢢ࣒࡛ࣛࡣ࠿࡞ࡾࣁ࣮ࢻ࡞ᩍ⫱ࣉࣟࢢ࣒ࣛࢆㄢࡍ
ࡢ࡛ࠊᏛᴗ࡟ᑓᛕ࡛ࡁࡿ⎔ቃసࡾࢆᡤᒓ௻ᴗ࣭⤌⧊࡜ࡢ㛫࡛༠㆟ࡢ࠺࠼㑅ᢤࡍࡿࠋ

㸦㸰㸧㹊㹇㹋㹑ࣉࣟࢢ࣒ࣛ࡟࠾ࡅࡿᒚಟ᪉ἲཬࡧಟ஢ᑂᰝࡢᴫせ࠙ಟኈ࣭༤ኈᚋᮇㄢ⛬㸳ᖺ⏝ࠚ‫ ۑ‬ᒚಟせ௳ಟኈㄢ⛬࡛ࡣࠊᣦᐃࡉࢀࡓᚲಟ⛉┠㸦ேయゎ๗Ꮫࠊ⏕⌮ᏛࠊᏛ㝿ᛂ⏝⛉┠㸹་⒪⏕άᨭ᥼ࢩࢫࢸ࣒Ꮫࠊⱥㄒ debateϨ࣭ϩ㸧13 ༢఩ࢆಟᚓࡋࠊࣉࣞࣜࢧ࣮ࢳࢆ᏶஢ࡍࡿࡇ࡜ࠋ
ᚲಟ⛉┠௨እࡢ⛉┠࡟ࡘ࠸࡚ࡣࠊ◊✲⛉ᣦᑟᩍᤵࠊ
㹊㹇㹋㹑ᣦᑟᩍᤵཬࡧ࣓ࣥࢱ࣮࡜┦ㄯࡋࠊࣉࣞࣜࢧ࣮ࢳ࡜㛵㐃ࡍࡿ⛉┠ࢆ࡛ࡁࡿࡔࡅᒚಟࡍࡿࡇ࡜ࢆ᥎ዡࡍࡿࠋ
༤ኈᚋᮇㄢ⛬࡛ࡣࠊࣉࣟࢢ࣒ࣛಟ஢ࡲ࡛࡟ⱥㄒ debateϪࠊϫࠊϬࢆ⩦ᚓࡋࠊ࢖ࣥࢱ࣮ࣥ
ࢩࢵࣉ㸦ಟኈ㸰ᖺḟ࠿ࡽᒚಟྍ⬟㸧ཬࡧ≉ู◊✲ࢆ᏶஢ࡍࡿࡇ࡜ࠋ
࣮࣒࣮࣒࣍ࣝ㸦ࢥ࣒ࣟ࢟࢘㸧㸸ཎ๎ẖ᭶᭱⤊㐌ࡢỈ᭙᪥ࡢ㸳㝈┠࡟⾜࠺ࡢ࡛ࠊᚲࡎฟᖍࡍࡿࡇ࡜ࠋ‫ ۑ‬㹊㹇㹋㹑࡛ࡢ◊✲ࢸ࣮࣐ࡢタᐃࠊ࣏࣮ࢺࣇ࢛ࣜ࢜
ẖᏛᮇࠊᣦᑟᩍᤵཬࡧ࣓ࣥࢱ࣮࡜┦ㄯࡢ࠺࠼ࠊ㹊㹇㹋㹑࡛ᐇ᪋ࡍࡿ◊✲ࢸ࣮࣐ཬࡧ◊✲ෆᐜࢆỴࡵࡿࠋ
ࡲࡓࠊᒚಟ࣭ᡂ⦼࣭㐩ᡂᗘࡢ⮬ᕫⅬ᳨ࠊᩍဨ࡟ࡼࡿホ౯ࢆ┠ⓗ࡜ࡋ࡚ࠊ࣏࣮ࢺࣇ࢛ࣜ࢜ࢆ
సᡂࡋࠊᣦᑟᩍဨࡀ㜀ぴ࡛ࡁࡿࡼ࠺࡟ࡍࡿࠋ
‫࣒ࣛࢢࣟࣉ ۑ‬ಟ஢ᑂᰝ࣭◊✲ᣦᑟྛᒚಟ⪅࡟ᑐࡋ࡚ࠊ㹊㹇㹋㹑ᣦᑟᩍᤵཬࡧ࣓ࣥࢱ࣮ࡀᣦᑟ࡟ᙜࡓࡿࠋ
◊✲⛉ཬࡧ㹊㹇㹋㹑ᣦᑟᩍᤵࡣࠊ
ẖᏛᖺࡢ⤊ࢃࡾ࡟ࣉࣟࢢ࣒ࣛᒚಟ࡟࠿࠿ࡿ◊✲ᣦᑟグ㘓᭩ࢆసᡂࡍࡿࠋ
࣭༤ኈㄽᩥ◊✲ᇶ♏ຊᑂᰝ㸦QE㸧ಟኈㄢ⛬㸰ᖺḟಟ஢๓࡟ QE ࢆ⾜࠺ࠋQE ᑂᰝ࡟ྜ᱁ࡍࡿࡇ࡜࡟ࡼࡾࠊᮏࣉࣟࢢ࣒ࣛࡢ L3 ࡜ࡋ࡚ᒚಟࡍࡿࡇ࡜ࡀ࡛ࡁࡿࠋ
‫۔‬ᑂᰝࡢᇶ‽ᮏࣉࣟࢢ࣒ࣛ࡟࠾࠸࡚ࠊ
௨ୗࡢᑂᰝᇶ‽࡟ࡼࡾ༤ኈㄽᩥ◊✲ࡢ୺యⓗ࡞㐙⾜࡟ᚲせ࡞ᇶ♏ⓗ▱㆑ཬࡧ⬟ຊࡀಟᚓࡉࢀ࡚࠸ࡿࡇ࡜ࢆᑂᰝࡋࠊ
࡜ࡶ࡟ᇶ‽࡟㐩ࡋ࡚࠸ࡿ࡜ࡉࢀࡓᒚಟ⏕࡟ࡘ
࠸࡚ࡣ QE ࡟ྜ᱁ࡋࡓࡇ࡜ࢆㄆࡵࡿࠋ
(1) ᡤᒓ◊✲⛉ࡢᒚಟ࡟࠾࠸࡚ࠊࡑࢀࡒࢀࡢ◊✲⛉ࡢᐃࡵࡿಟኈᏛ఩ྲྀᚓ࡟ᚲせ࡞༢఩ᩘ➼ࡢᇶ‽࡟㐩ࡋ࡚࠸ࡿࡇ࡜ࠋ
(2) ᡤᒓ◊✲⛉ࡢᐃࡵࡿಟኈㄽᩥࡀᙜヱ◊✲⛉࡟ᥦฟࡉࢀ࡚࠸ࡿࡇ࡜ࠋ
(3) ᡤᒓ◊✲⛉࡟࠾࠸࡚༤ኈᚋᮇㄢ⛬㐍Ꮫヨ㦂࡟ྜ᱁ࡋ࡚࠸ࡿࡇ࡜ࠋ
(4) ᮏࣉࣟࢢ࣒ࣛࡢ࣒࢝ࣜ࢟ࣗࣛ㸦ⱥㄒຊᑂᰝࢆྵࡴ㸧ࡢᒚಟ࡟࠾࠸࡚ࠊᮏࣉࣟࢢ࣒ࣛࡀู

࡟ᐃࡵࡿ༢఩ᩘ➼ࡢᇶ‽࡟㐩ࡋ࡚࠸ࡿࡇ࡜ࠋ
(5) ༤ኈᚋᮇㄢ⛬࡟࠾ࡅࡿ LIMS ࡢ◊✲ィ⏬ࢆసᡂࡋࠊࡑࡢෆᐜࡀᮏࣉࣟࢢ࣒ࣛࡀồࡵࡿ༤ኈㄽᩥ◊✲╔ᡭࡢࡓࡵࡢせ௳ࢆ‶ࡓࡋ࡚࠸ࡿࡇ࡜ࠋ
‫۔‬ᑂᰝᡭ⥆ࡁࠊᥦฟ≀ᒚಟ⏕ࡣࠊ㸰᭶ୖ᪪ࡲ࡛࡟௨ୗࡢࡶࡢࢆᥦฟࡍࡿࡇ࡜
(1) ᡤᒓ◊✲⛉ཬࡧࣉࣟࢢ࣒ࣛࡢಟኈㄢ⛬࡛ᐇ᪋ࡋࡓࣉࣞࣜࢧ࣮ࢳ࡟ࡘ࠸࡚ⱥㄒ࡟ࡼࡿ࣏ࣞ
࣮ࢺ(2) ༤ኈᚋᮇㄢ⛬㐍Ꮫᚋࡢࣉࣟࢢ࣒࡛ࣛᐇ᪋ࡍࡿ≉ู◊✲ࡢ◊✲ィ⏬᭩㸦᪥ᮏㄒࡲࡓࡣⱥㄒ㸧(1)ཬࡧ(2)࡟ࡘ࠸࡚ࠊཱྀ㢌ヨၥࢆ⾜࠺ࠋ㸦㸱᭶ୖ᪪㸧࣭ࣉࣟࢢ࣒ࣛಟ஢ᑂᰝ
㸳ᖺḟ࡟ࡣࠊ
ᒚಟ⏕ࡣࠊLIMS ࡬≉ู◊✲ㄽᩥ(thesis)ࢆῧ࠼࡚ࣉࣟࢢ࣒ࣛಟ஢ᑂᰝ㢪ࡢᥦฟࢆ⾜࠺ࠋࣉࣟࢢ࣒ࣛಟ஢ᑂᰝጤဨ఍ࡣࠊಟ஢ㄪᰝጤဨࢆ㑅ᐃࡋࠊࣉࣟࢢ࣒ࣛಟ஢ㄪᰝࢆ⾜࠺ࠋಟ஢ᑂᰝጤဨ఍ࡣࠊㄪᰝ⤖ᯝࢆᑂᰝࡋࠊࡑࡢ⤖ᯝࢆࣘࢽࢵࢺᩍᤵ఍࡟ሗ࿌ࡍࡿࠋ
ࣘࢽࢵࢺᩍᤵ఍ࡣࠊࣉࣟࢢ࣒ࣛࡢಟ஢ุᐃࢆ⾜࠸ࠊࡑࡢ⤖ᯝࢆ඲Ꮫࡢ࣮ࣜࢹ࢕ࣥࢢࣉࣟࢢࣛ
࣒㐠Ⴀጤဨ఍࡬ሗ࿌ࡍࡿࠋ
඲Ꮫࡢ࣮ࣜࢹ࢕ࣥࢢࣉࣟࢢ࣒ࣛ㐠Ⴀጤဨ఍ࡣࠊࣉࣟࢢ࣒ࣛࡢಟ஢ᑂᰝࢆ⾜࠸ࠊ◊✲⛉࡬ಟ஢ᑂᰝ⤖ᯝ࡟ࡘ࠸࡚ࠊሗ࿌ࢆ⾜࠺ࠋ◊✲⛉࡟࠾ࡅࡿ༤ኈᏛ఩ㄽᩥࡢᑂᰝ࡟ྜ᱁ࡍࢀࡤࠊ
࣮ࣜࢹ࢕ࣥࢢࣉࣟࢢ࣒ࣛಟ஢ࡢ௜グࡀ࡞ࡉࢀࡿࠋ࣭Ꮫ఩࡟ࡘ࠸࡚ࡣࠊ◊✲⛉ࡢᏛ఩࡟ࣉࣟࢢ࣒ࣛྡࢆ௜グ༤ኈ㸦་⛉Ꮫࠊࡲࡓࡣ་Ꮫࠊࡲࡓࡣே㛫೺ᗣ⛉Ꮫࠊࡲࡓࡣ⸆⛉Ꮫࠊࡲࡓࡣ⸆ᏛࠊࡲࡓࡣᕤᏛ㸧ࠕ඘ᐇࡋࡓ೺ᗣ㛗ᑑ♫఍ࢆ⠏ࡃ⥲ྜ་⒪㛤Ⓨ࣮ࣜࢲ࣮⫱ᡂࣉࣟࢢ࣒ࣛࠖࡢಟ஢
࠙༤ኈㄢ⛬  ᖺ⏝ࠚ‫ ۑ‬ᒚಟせ௳ᣦᐃࡉࢀࡓᚲಟ⛉┠㸦ேయゎ๗Ꮫࠊ⏕⌮Ꮫࠊ་⒪⤒῭ㄽࠊ▱ⓗ㈈⏘㸤ᅜ㝿ᶆ‽໬ࠊᏛ㝿ᛂ⏝⛉┠㸹་⒪⏕άᨭ᥼ࢩࢫࢸ࣒Ꮫࠊⱥㄒ debateϩ㹼ϬཬࡧᶵᲔᕤᏛᇶ♏ࡲࡓࡣᮦᩱ໬Ꮫᇶ♏
࠿ࡽ㸯⛉┠㸧㸯㸳༢఩௨ୖࢆಟᚓࡍࡿࡇ࡜ࠋ
ࣉࣟࢢ࣒ࣛಟ஢ࡲ࡛࡟࢖ࣥࢱ࣮ࣥࢩࢵࣉཬࡧ≉ู◊✲ࢆ᏶஢ࡍࡿࡇ࡜ࠋ
࣮࣒࣮࣒࣍ࣝ㸦ࢥ࣒ࣟ࢟࢘㸧㸸ཎ๎ẖ᭶᭱⤊㐌ࡢỈ᭙᪥ࡢ㸳㝈┠࡟⾜࠺ࡢ࡛ࠊᚲࡎฟᖍࡍࡿࡇ࡜ࠋ‫ ۑ‬㹊㹇㹋㹑࡛ࡢ◊✲ࢸ࣮࣐ࡢタᐃࠊ࣏࣮ࢺࣇ࢛ࣜ࢜
ẖᏛᮇࠊᣦᑟᩍᤵཬࡧ࣓ࣥࢱ࣮࡜┦ㄯࡢ࠺࠼ࠊ㹊㹇㹋㹑࡛ᐇ᪋ࡍࡿ◊✲ࢸ࣮࣐ཬࡧ◊✲ෆᐜࢆỴࡵࡿࡇ࡜ࠋ

ࡲࡓࠊᒚಟ࣭ᡂ⦼࣭㐩ᡂᗘࡢ⮬ᕫⅬ᳨ࠊᩍဨ࡟ࡼࡿホ౯ࢆ┠ⓗ࡜ࡋ࡚ࠊ࣏࣮ࢺࣇ࢛ࣜ࢜ࢆ
సᡂࡋࠊᣦᑟᩍဨࡀ㜀ぴ࡛ࡁࡿࡼ࠺࡟ࡍࡿࡇ࡜ࠋ
‫࣒ࣛࢢࣟࣉ ۑ‬ಟ஢ᑂᰝ࣭◊✲ᣦᑟྛᒚಟ⪅࡟ᑐࡋ࡚ࠊ㹊㹇㹋㹑ᣦᑟᩍᤵཬࡧ࣓ࣥࢱ࣮ࡀᣦᑟ࡟ᙜࡓࡿࠋ
◊✲⛉ཬࡧ㹊㹇㹋㹑ᣦᑟᩍᤵࡣࠊẖᏛᖺࡢ⤊ࢃࡾ࡟ࣉࣟࢢ࣒ࣛᒚಟ࡟࠿࠿ࡿ◊✲ᣦᑟグ㘓᭩ࢆసᡂࡍࡿࠋ
࣭ࣉࣟࢢ࣒ࣛಟ஢ᑂᰝ
㸲ᖺḟ࡟ࡣࠊ
ᒚಟ⏕ࡣࠊLIMS ࡬≉ู◊✲ㄽᩥ(thesis)ࢆῧ࠼࡚ࣉࣟࢢ࣒ࣛಟ஢ᑂᰝ㢪ࡢᥦฟࢆ⾜࠺ࠋࣉࣟࢢ࣒ࣛಟ஢ᑂᰝጤဨ఍ࡣࠊಟ஢ㄪᰝጤဨࢆ㑅ᐃࡋࠊࣉࣟࢢ࣒ࣛಟ஢ㄪᰝࢆ⾜࠺ࠋಟ஢ᑂᰝጤဨ఍ࡣࠊㄪᰝ⤖ᯝࢆᑂᰝࡋࠊࡑࡢ⤖ᯝࢆࣘࢽࢵࢺᩍᤵ఍࡟ሗ࿌ࡍࡿࠋ
ࣘࢽࢵࢺᩍᤵ఍ࡣࠊࣉࣟࢢ࣒ࣛࡢಟ஢ุᐃࢆ⾜࠸ࠊࡑࡢ⤖ᯝࢆ඲Ꮫࡢ࣮ࣜࢹ࢕ࣥࢢࣉࣟࢢࣛ
࣒㐠Ⴀጤဨ఍࡬ሗ࿌ࡍࡿࠋ
඲Ꮫࡢ࣮ࣜࢹ࢕ࣥࢢࣉࣟࢢ࣒ࣛ㐠Ⴀጤဨ఍ࡣࠊࣉࣟࢢ࣒ࣛࡢಟ஢ᑂᰝࢆ⾜࠸ࠊ◊✲⛉࡬ಟ஢ᑂᰝ⤖ᯝ࡟ࡘ࠸࡚ࠊሗ࿌ࢆ⾜࠺ࠋ◊✲⛉࡟࠾ࡅࡿ༤ኈᏛ఩ㄽᩥࡢᑂᰝ࡟ྜ᱁ࡍࢀࡤࠊ࣮ࣜࢹ࢕ࣥࢢࣉࣟࢢ࣒ࣛಟ஢ࡢ௜グࡀࡉࢀࡿࠋ࣭Ꮫ఩࡟ࡘ࠸࡚ࡣࠊ◊✲⛉ࡢᏛ఩࡟ࣉࣟࢢ࣒ࣛྡࢆ௜グ༤ኈ㸦་⛉Ꮫࠊࡲࡓࡣ་Ꮫࠊࡲࡓࡣே㛫೺ᗣ⛉Ꮫࠊࡲࡓࡣ⸆⛉Ꮫࠊࡲࡓࡣࠊ⸆ᏛࡲࡓࡣᕤᏛ㸧ࠕ඘ᐇࡋࡓ೺ᗣ㛗ᑑ♫఍ࢆ⠏ࡃ⥲ྜ་⒪㛤Ⓨ࣮ࣜࢲ࣮⫱ᡂࣉࣟࢢ࣒ࣛࠖࡢಟ஢
࠙༤ኈᚋᮇㄢ⛬⦅ධᏛ⏝ࠚ‫ ۑ‬ᒚಟせ௳༤ኈᚋᮇㄢ⛬࡛ࡣࠊᣦᐃࡉࢀࡓᚲಟ⛉┠㸦Ꮫ㝿ᛂ⏝⛉┠㸸་⒪⏕άᨭ᥼ࢩࢫࢸ࣒Ꮫ㸧2 ༢఩ཬࡧⱥㄒ debateϪࠊϫࠊϬࠊ᭱ඛ➃ᶵჾ₇⩦ࢆಟᚓࡋࠊ࢖ࣥࢱ࣮ࣥࢩࢵࣉཬࡧ≉ู◊✲ࢆ᏶஢ࡍࡿࡇ࡜ࠋᚲಟ⛉┠௨እࡢ⛉┠࡟ࡘ࠸࡚ࡣࠊ◊✲⛉ᣦᑟᩍᤵࠊ㹊㹇㹋㹑ᣦᑟᩍᤵཬࡧ࣓
ࣥࢱ࣮࡜┦ㄯࡋࠊ≉ู◊✲࡜㛵㐃ࡍࡿ⛉┠ࢆ࡛ࡁࡿࡔࡅᒚಟࡍࡿࡇ࡜ࢆ᥎ዡࡍࡿࠋ
࣮࣒࣮࣒࣍ࣝ㸦ࢥ࣒ࣟ࢟࢘㸧㸸ཎ๎ẖ᭶᭱⤊㐌ࡢỈ᭙᪥ࡢ㸳㝈┠࡟⾜࠺ࡢ࡛ࠊᚲࡎฟᖍࡍࡿࡇ࡜ࠋ‫ ۑ‬㹊㹇㹋㹑࡛ࡢ◊✲ࢸ࣮࣐ࡢタᐃࠊ࣏࣮ࢺࣇ࢛ࣜ࢜
ẖᏛᮇࠊᣦᑟᩍᤵཬࡧ࣓ࣥࢱ࣮࡜┦ㄯࡢ࠺࠼ࠊ㹊㹇㹋㹑࡛ᐇ᪋ࡍࡿ◊✲ࢸ࣮࣐ཬࡧ◊✲ෆᐜࢆỴࡵࡿࠋ
ࡲࡓࠊᒚಟ࣭ᡂ⦼࣭㐩ᡂᗘࡢ⮬ᕫⅬ᳨ࠊᩍဨ࡟ࡼࡿホ౯ࢆ┠ⓗ࡜ࡋ࡚ࠊ࣏࣮ࢺࣇ࢛ࣜ࢜ࢆ

సᡂࡋࠊᣦᑟᩍဨࡀ㜀ぴ࡛ࡁࡿࡼ࠺࡟ࡍࡿࠋ
‫࣒ࣛࢢࣟࣉ ۑ‬ಟ஢ᑂᰝ࣭◊✲ᣦᑟྛᒚಟ⪅࡟ᑐࡋ࡚ࠊ㹊㹇㹋㹑ᣦᑟᩍᤵཬࡧ࣓ࣥࢱ࣮ࡀᣦᑟ࡟ᙜࡓࡿࠋ
◊✲⛉ཬࡧ㹊㹇㹋㹑ᣦᑟᩍᤵࡣࠊ
ẖᏛᖺࡢ⤊ࢃࡾ࡟ࣉࣟࢢ࣒ࣛᒚಟ࡟࠿࠿ࡿ◊✲ᣦᑟグ㘓᭩ࢆసᡂࡍࡿࠋ
࣭ࣉࣟࢢ࣒ࣛಟ஢ᑂᰝ
㸳ᖺḟ࡟ࡣࠊ
ᒚಟ⏕ࡣࠊLIMS ࡬≉ู◊✲ㄽᩥ(thesis)ࢆῧ࠼࡚ࣉࣟࢢ࣒ࣛಟ஢ᑂᰝ㢪ࡢᥦฟࢆ⾜࠺ࠋࣉࣟࢢ࣒ࣛಟ஢ᑂᰝጤဨ఍ࡣࠊಟ஢ㄪᰝጤဨࢆ㑅ᐃࡋࠊࣉࣟࢢ࣒ࣛಟ஢ㄪᰝࢆ⾜࠺ࠋಟ஢ᑂᰝጤဨ఍ࡣࠊㄪᰝ⤖ᯝࢆᑂᰝࡋࠊࡑࡢ⤖ᯝࢆࣘࢽࢵࢺᩍᤵ఍࡟ሗ࿌ࡍࡿࠋ
ࣘࢽࢵࢺᩍᤵ఍ࡣࠊࣉࣟࢢ࣒ࣛࡢಟ஢ุᐃࢆ⾜࠸ࠊࡑࡢ⤖ᯝࢆ඲Ꮫࡢ࣮ࣜࢹ࢕ࣥࢢࣉࣟࢢࣛ
࣒㐠Ⴀጤဨ఍࡬ሗ࿌ࡍࡿࠋ
඲Ꮫࡢ࣮ࣜࢹ࢕ࣥࢢࣉࣟࢢ࣒ࣛ㐠Ⴀጤဨ఍ࡣࠊࣉࣟࢢ࣒ࣛࡢಟ஢ᑂᰝࢆ⾜࠸ࠊ◊✲⛉࡬ಟ஢ᑂᰝ⤖ᯝ࡟ࡘ࠸࡚ࠊሗ࿌ࢆ⾜࠺ࠋ◊✲⛉࡟࠾ࡅࡿ༤ኈᏛ఩ㄽᩥࡢᑂᰝ࡟ྜ᱁ࡍࢀࡤࠊ
࣮ࣜࢹ࢕ࣥࢢࣉࣟࢢ࣒ࣛಟ஢ࡢ௜グࡀ࡞ࡉࢀࡿࠋ࣭Ꮫ఩࡟ࡘ࠸࡚ࡣࠊ◊✲⛉ࡢᏛ఩࡟ࣉࣟࢢ࣒ࣛྡࢆ௜グ༤ኈ㸦་⛉Ꮫࠊࡲࡓࡣ་Ꮫࠊࡲࡓࡣே㛫೺ᗣ⛉Ꮫࠊࡲࡓࡣ⸆⛉Ꮫࠊࡲࡓࡣ⸆ᏛࠊࡲࡓࡣᕤᏛ㸧ࠕ඘ᐇࡋࡓ೺ᗣ㛗ᑑ♫఍ࢆ⠏ࡃ⥲ྜ་⒪㛤Ⓨ࣮ࣜࢲ࣮⫱ᡂࣉࣟࢢ࣒ࣛࠖࡢಟ஢
㸦㸱㸧ࢹ࢕ࣉ࣐࣏ࣟࣜࢩ࣮
་Ꮫⓗ▱㆑ࢆ༑ศ࡟Ꮫ⩦ࡋ఍ᚓࡋࡓࠊ་⛉Ꮫ࣭ᕤᏛ࣭⸆Ꮫ࡞࡝ࡢᐇ㦂࣭◊✲ࡀ࡛ࡁࡿ◊✲⪅࡛ࠊᾏእࡢ◊✲᪋タ࣭௻ᴗ࣭බඹ⤌⧊࡞࡝࡛ά㌍࡛ࡁࡿࡼ࠺༑ศ࡞ⱥㄒຊ࣭ࢹ࢕࣮࣋ࢺຊ
ࢆࡶࡕࠊ඲ୡ⏺ⓗ࡟㐍⾜ࡍࡿ㧗㱋♫఍ࡢ⌧≧࡜ᑗ᮶ࢆ⮬ศ࡛ಠ▔ⓗ࡟⪃ᐹࡋࠊከᵝ࡞ேࡸ⤌⧊࡜༠ຊࡋ࡚ၥ㢟ⅬࢆゎỴࡍࡿࡓࡵ࡟ࠊࡉࡲࡊࡲ࡞⮬ศࡢ▱㆑࡜ᡭἲࢆ⏝࠸ࡿࡇ࡜ࡀ࡛ࡁࠊ
㧗㱋⪅ࡀᏳᚰࡋ࡚⏕ά࡛ࡁࡿ⎔ቃࢆసࡾୖࡆࡽࢀࡿே≀࡟࡞ࡾࠊ࠿࠿ࡿศ㔝࡟࠾ࡅࡿ᪥ᮏࠊ
࢔ࢪ࢔ࠊୡ⏺ࡢ࣮ࣜࢲ࣮࡜࡞ࡿࡇ࡜ࠋ

㸳㸬ᒚಟ࢝ࢸࢦ࣮ࣜ࡟ࡘ࠸࡚
ᮏࣉࣟࢢ࣒࡛ࣛ㛤タࡍࡿ⛉┠ࡣู⾲ࡢ㏻ࡾ࡛࠶ࡾࠊࡑࡢᴫせࡣ௨ୗࡢ㏻ࡾ࡛࠶ࡿࠋ
ᇶ┙⛉┠࣭ᕤᏛࠊ⸆Ꮫࠊ་Ꮫ࣭⏕≀Ꮫ་ᕤᏛ㡿ᇦࡢ◊✲࡟ᚲせ࡜࡞ࡿᕤᏛࠊ་Ꮫࠊ⸆Ꮫ࡟㛵ࡍࡿᇶ♏▱㆑ࢆ⩦ᚓࡍࡿࠋᕤᏛ㒊ฟ㌟

⪅࠿⏕≀㛵ಀᏛ㒊ฟ㌟ྥࡅࡢᶆ‽ᒚಟ࣓ࢽ࣮ࣗࢆᥦ♧ࠋࡑࢀࢆཧ⪃࡟⛉┠ࢆ㑅ᢥࡍࡿࠋ
࣭་⒪೔⌮
་⒪೔⌮࡟ࡘ࠸࡚Ꮫ⩦ࡍࡿࠋᩘ⌮⛉Ꮫ⛉┠ࢩ࣑࣮ࣗࣞࢩࣙࣥࢆ୰ᚰ࡜ࡋࡓࡶࡢ࡛ࠊᮏࣉࣟࢢ࣒࡛ࣛࡣࠊ་⒪⤒῭Ꮫ࡜࡜ࡶ࡟㧗㱋໬♫఍ࡢᑗ᮶ண ➼࡟ᚲせ࡞㔜せ࡞⛉┠࡜ࡋ࡚᥎ዡ⛉┠࡜ࡍࡿࠋ་⒪⤒῭Ꮫ
㧗㱋໬♫఍࡟࠾ࡅࡿ་⒪⤒῭Ꮫⓗㄢ㢟ࠊ▱ⓗ㈈⏘ࠊᅜ㝿ᶆ‽໬ࡢ⌮ゎຊࢆ㌟࡟௜ࡅࡉࡏࡿࠋ་⒪ᕤᏛ≉ูㅮ⩏༠ຊ௻ᴗ࠿ࡽὴ㐵ࡉࢀࡓㅮᖌ࡟ࡼࡾࠊ་⒪࣭೺ᗣ࣭ࢣ࢔࡞࡝࡟㛵ࡋࠊ᭱ඛ➃ࡢᢏ⾡ࡸ⌧ሙࡢㄢ㢟➼࡟ࡘ࠸࡚ㅮ⩏ࢆཷࡅࠊ㆟ㄽࡍࡿࠋ
Ꮫ㝿ᛂ⏝⛉┠≉ู◊✲࡛⾜࠺◊✲㡿ᇦ࡟ᛂࡌ࡚⏝ពࡉࢀࡓᑓ㛛⛉┠
ⱥㄒ GHEDWHᅜ㝿ⓗ࣮ࣜࢲ࣮࡟୙ྍḞ࡞⬟ຊ࡜ࡋ࡚ⱥㄒ࡛ࡢࢥ࣑ࣗࢽࢣ࣮ࢩࣙࣥຊࢆ㣴࠺ࠋ࢖ࣥࢱ࣮ࣥࢩࢵࣉ
௻ᴗ࡟࠾࠸࡚ࠊ◊✲㛤Ⓨ࡞࡝࡟ࡘ࠸࡚ࠊᐇ㊶ࡋ࡞ࡀࡽ⌮ゎࡋࠊ≉ู◊✲࡟ά࠿ࡍࠋ⾜ᨻᶵ㛵ࠊᅜ㝿ᶵ㛵࡟▷ᮇ◊ಟࢆ⾜࠸ࠊチㄆྍࡸᅜ㝿ᶆ‽໬ࡢ௙⤌ࡳࠊㄢ㢟࡟ࡘ࠸࡚⌮ゎࢆ῝ࡵࡿࠋࣉࣞࣜࢧ࣮ࢳ
◊✲ᐊ࣮ࣟࢸ࣮ࢩࣙࣥ࡞࡝ࢆ㏻ࡌࠊᑓ㛛௨እࡢศ㔝࡟㛵ࡍࡿ⌮ゎࢆᗈࡆࡿࠋ◊✲⪅࡜ࡋ࡚ࡢᇶ♏⬟ຊࢆ㣴࠸≉ู◊✲ࡢ◊✲ィ⏬ࢆసᡂࡍࡿࠋ
≉ู◊✲ࣉࣞࣜࢧ࣮ࢳ࡛సᡂࡋࡓ◊✲ィ⏬࡟ᇶ࡙࠸࡚༤ኈࡢ◊✲ࢆ㐙⾜ࡋࠊᏛ఩ྲྀᚓ࡜࣮ࣜࢹ࢕ࣥ
ࢢࣉࣟࢢ࣒ࣛࡢಟ஢ࢆ┠ᣦࡍࠋ㸴 ࣉࣟࢢ࣒ࣛᒚಟ⪅࡬ࡢᨭ᥼

ࣉࣟࢢ࣒ࣛᒚಟ⪅࡟ࡣࠊ࣮ࣜࢹ࢕ࣥࢢ༤ኈㄢ⛬࡟࠾ࡅࡿᒚಟཬࡧᏛ఩◊✲࡟ᑓᛕࡍࡿࡓࡵ
ࡢ௨ୗࡢࡼ࠺࡞⤒῭ᨭ᥼ࢆ⾜࠺ࠋ࡞࠾ࠊᮏࣉࣟࢢ࣒ࣛࡣࠊᩥ㒊⛉Ꮫ┬ࠕ༤ኈㄢ⛬ᩍ⫱࣮ࣜࢹ࢕ࣥࢢࣉࣟࢢ࣒ࣛࠖࡢ᥇ᢥࢆཷ
ࡅ࡚ᐇ᪋ࡋ࡚࠸ࡿࡓࡵࠊ
ࠕ༤ኈㄢ⛬ᩍ⫱࣮ࣜࢹ࢕ࣥࢢࣉࣟࢢ࣒ࣛࠖ࡟ࡼࡿዡບ㔠➼ࡢ⤒῭ⓗᨭ᥼ᮇ㛫࡟ࡘ࠸࡚ࡣࠊᖹᡂ㸱㸯ᖺ㸱᭶ᮎࡲ࡛ࡢணᐃ࡜࡞ࡗ࡚࠸ࡿࠋ

‫≉۔‬ᚅ⏕ዡບ㔠௨ୗࡢཷ⤥㈨᱁ࢆࡍ࡭࡚‶ࡓࡍඃ⚽࡞ᒚಟ⪅࡟ᑐࡋ࡚≉ᚅ⏕ዡບ㔠ࢆᨭ⤥ࡍࡿࠋᨭ⤥㢠ཬࡧᨭ⤥⥅⥆࡟ࡘ࠸࡚ࡣࠊ㑅ᢤ᫬ཬࡧྛᏛᖺᮎ࡟Ỵᐃࡉࢀࠊᖺᗘࡈ࡜࡟ぢ┤ࡉࢀࡿࠋࡲࡓࠊ
ዡບ㔠ཷ⤥⪅ࡢẶྡࡣཷ⤥㛤ጞ๓࡟Ꮫෆᥖ♧ཬࡧ㹊㹇㹋㹑࣮࣒࣮࣍࣌ࢪ࡟࡚බ⾲ࡍࡿࠋ࠙ཷ⤥㈨᱁ࠚ
(1) ࣉࣟࢢ࣒ࣛᒚಟ⪅㑅ᢤヨ㦂࡟ྜ᱁ࡋࡓᮏࣉࣟࢢ࣒ࣛࡢᒚಟ⪅(2) ྛ✀ዡᏛ㔠➼ࡢᑵᏛᨭ᥼⤒㈝㸦ᮏᏛࡢᐃࡵࡿᤵᴗᩱ➼ච㝖ࡣ㝖ࡃ㸧ࢆཷࡅ࡚࠸࡞࠸⪅ࡓࡔࡋࠊᅜ㈝␃Ꮫ⏕➼࡛ᮏዡບ㔠ࢆ㎡㏥ࡋࡓ⪅ࡣࠊ௚ࡢዡᏛ㔠ࢆཷࡅ࡞ࡀࡽᮏࣉࣟࢢ࣒ࣛ
ࢆᒚಟࡍࡿࡇ࡜ࡀ࡛ࡁࡿࠋ
(3) ዡບ㔠௨እࡢ཰ධ㸦࢔ࣝࣂ࢖ࢺࡢ⤥୚➼㸧ࢆᚓ࡚࠸࡞࠸⪅ࡓࡔࡋࠊ◊✲ᡂᯝࡢබ⾲࡟క࠺ㅰ㔠ࠊⴭసᩱ࠾ࡼࡧ TA࣭RA ࡢ⤥୚㸦ᮏࣉࣟࢢ࣒ࣛ࡟࠾࠸
࡚ᮏࣉࣟࢢ࣒ࣛࡢᐇ᪋࡟୙ྍḞ࡜ุ᩿ࡉࢀࡿሙྜ࡟㝈ࡾࠊ㐌㸳᫬㛫ࢆୖ㝈࡜ࡍࡿࠋ㸧➼࡟㝈ࡾࠊࡇࢀࢆ㝖እࡍࡿࠋ(4) ᮏᏛ኱Ꮫ㝔ࡢᅾ⡠ᮇ㛫㸦ఇᏛᮇ㛫ࢆ㝖ࡃ㸧ࡀᶆ‽ಟᴗᖺ㝈࡟㸯ᖺࢆຍ࠼ࡓᮇ㛫ࢆ㉸࠼࡞࠸⪅(5) ᮏࣉࣟࢢ࣒ࣛ࡟࠾ࡅࡿᡂ⦼➼ホ౯࡟࠾࠸࡚≉࡟ඃ⚽࡜ㄆࡵࡽࢀࡿ⪅(6) ᮏࣉࣟࢢ࣒ࣛࡀ㸳ᖺ୍㈏ࡢᩍ⫱◊✲ㄢ⛬࡛࠶ࡿࡇ࡜ࢆ஢ゎࡍࡿ⪅࠙ཷ⤥㈨᱁ࡢ႙ኻ᮲௳ࠚ ཷ⤥⪅ࡀḟࡢྛྕࡢ୍࡟ヱᙜࡍࡿሙྜࡣࠊࡑࡢ㈨᱁ࢆኻ࠺ࠋ
(1) ୖグ࡟ᐃࡵࡿཷ⤥㈨᱁ࢆኻࡗࡓ࡜ࡁࠋ
(2) ཷ⤥⪅࠿ࡽࡢ㎡㏥ᒆࡀཷ⌮ࡉࢀࡓ࡜ࡁࠋ
(3) ዡບ㔠࡟ࡘ࠸࡚ᥦฟࡉࢀࡓ᭩㢮࡟⹫ഇࡢグ㍕ࡀ࠶ࡿ࡜ࡁࠋ
(4) ఇᏛཪࡣ㏥Ꮫࡋࡓ࡜ࡁࠊ࠾ࡼࡧ㝖⡠ࡉࢀࡓ࡜ࡁࠋ
(5) ி㒔኱Ꮫ㏻๎ࡢつᐃ࡟ࡼࡾᠬᡄฎศࢆཷࡅࡓ࡜ࡁࠋ

࠙ᡤᚓ⛯࣭ఫẸ⛯࣭♫఍ಖ㝤➼࡟ࡘ࠸࡚ࠚϸ ዡບ㔠ࡣࠕ㞧ᡤᚓࠖ࡜ࡋ࡚ྲྀࡾᢅࢃࢀࡿࡓࡵࠊ※Ἠᚩ཰ࡣ⾜ࢃ࡞࠸ࠋϹ ዡບ㔠ࡣࠕ㞧ᡤᚓࠖ࡜ࡋ࡚ㄢ⛯ᑐ㇟࡜࡞ࡿࡓࡵࠊཷ⤥⪅ࡣᐙ᪘ࡢ⛯ἲୖࡢᢇ㣴ぶ᪘࠿ࡽእࢀ࡞ࡅࢀࡤ࡞ࡽ࡞࠸ࠋϺ ཷ⤥⪅ࡣ⮬㌟࡛ᚲࡎ☜ᐃ⏦࿌ࡢᡭ⥆ࡁ㸦ẖᖺ 3 ᭶ 15 ᪥ࡲ࡛࡟㸧ࢆ⾜ࡗࡓୖ࡛ࠊᡤᚓ
⛯࣭ఫẸ⛯⣡௜࡟ಀࡿドᣐ᭩㢮ࢆ LIMS ஦ົᐊ࡬ᥦฟࡋ࡞ࡅࢀࡤ࡞ࡽ࡞࠸ࠋϻ ཷ⤥⪅ࡣಶே࡛ᅜẸ೺ᗣಖ㝤࣭ᅜẸᖺ㔠ಖ㝤࡬ຍධࡍࡿࡇ࡜ࠋϼ ᅜẸᖺ㔠ಖ㝤ࡢᏛ⏕⣡௜≉౛ไᗘࡣ㐺⏝㝖እ࡜࡞ࡿࡢ࡛ὀពࡍࡿࡇ࡜ࠋ
㸦๓⣡ࡸཱྀᗙ
᣺᭰࡟ࡼࡿ๭ᘬไᗘࡣ࠶ࡿࠋ
㸧Ͻ ␃Ꮫ⏕ࡢሙྜࡣࠊ⛒⛯᮲⣙ࡢ⥾⤖ࡢ᭷↓࡟ࡼࡾྲྀᢅࡀኚࢃࡿࡓࡵࠊὀពࡍࡿࡇ࡜ࠋϾ ྛ✀ᡭ⥆ࡁ࡟ࡘ࠸࡚ࡣࠊᒃఫࡍࡿᕷ༊⏫ᮧ࡬ၥ࠸ྜࢃࡏࡿࡇ࡜ࠋ

‫✲◊۔‬άື⤒㈝
ࣉࣟࢢ࣒ࣛᒚಟ⪅ࡢ◊✲άືࢆᨭ᥼ࡍࡿࡓࡵࠊ◊✲άື⤒㈝ࢆᨭ⤥ࡍࡿࠋ◊✲㈝ࡢᖺ㛫ࢆ㏻ࡋ࡚ࡢ᭷ຠ࡞౑࠸᪉ࠊ◊✲┠ⓗ࡟ྜࡗࡓ≀ရࡢ㉎ධ࡞࡝ࢆࠊ◊✲⪅࡜ࡋ࡚㐺ษ࡟ᇳ⾜࡛ࡁࡿࡼ࠺࡟࡞ࡿࡓࡵ࡟ࠊ◊✲㈝ࢆ⏦ㄳෆᐜ࡟ࡼࡗ࡚ࠊ୍ᐃ㝈ᗘ㢠ࡲ࡛㓄ศࡍࡿࠋヲ⣽࡟ࡘ࠸࡚ࡣࠊ༤ኈㄢ⛬ᩍ⫱࣮ࣜࢹ࢕ࣥࢢࣉࣟࢢ࣒ࣛᒚಟ⏕◊✲άື⤒㈝ྲྀᢅせ㡿ࠊ࠾ࡼࡧ /,06 ࣉࣟࢢ࣒ࣛᩍᤵ఍࡛ỴࡵࡿࠋᚲࡎࠊHOHDUQLQJ ࡛ࠊ◊✲㈝ࡢ౑⏝ࡢὀពⅬࢆᏛࡪࡇ࡜ࠋ⏦ㄳ㈨᱁ࡣࠊಟኈㄢ⛬㸰ᖺḟ௨ୖ࡛ࠊ㑅⪃ጤဨ఍࡛⏦ㄳෆᐜࠊ⏦ㄳ㢠ࢆᑂᰝࡋ࡚ࠊ㓄ศ㢠ࢆỴᐃࡍࡿࠋ
ເ㞟せ㡯ࡣࠊู㏵᱌ෆࡍࡿࠋ

䝥䝻䜾䝷䝮ᢸᙜ⪅୍ぴ䠄ᖹᡂ㻞㻥ᖺᗘ䠅ᖹᡂ㻟㻜ᖺ㻟᭶㻟㻝᪥⌧ᅾ
ഛ䚷䚷⪃

Ặ䚷䚷ྡ

ᡤ䚷䚷ᒓ

ᑓᨷ➼

⫋䚷䚷ྡ



ୖᮏ䚷ఙ஧

་Ꮫ◊✲⛉

་Ꮫ

ᩍᤵ

䝥䝻䜾䝷䝮㈐௵⪅䞉་Ꮫ◊✲⛉㛗



⚟ᒣ䚷⚽┤

Ꮫ㝿⼥ྜᩍ⫱◊✲᥎㐍䝉䞁䝍䞊೺ᗣ㛗ᑑ♫఍䛾⥲ྜ་⒪㛤Ⓨ䝴䝙䝑䝖≉௵ᩍᤵ䝥䝻䜾䝷䝮䝁䞊䝕䜱䝛䞊䝍䞊



Ώ㑓䚷኱

་Ꮫ◊✲⛉

་Ꮫ

ᩍᤵ



ⴗཎ䚷ṇᩄ

་Ꮫ◊✲⛉

་Ꮫ

ᩍᤵ



ᩪ⸨䚷㏻⣖

་Ꮫ◊✲⛉

་Ꮫ

ᩍᤵ

Ṋ⏣䚷ಇ୍

་Ꮫ◊✲⛉

་Ꮫ

ᩍᤵ

ᯇ⏣䚷㐨⾜

་Ꮫ◊✲⛉

་Ꮫ

ᩍᤵ

⩚㈡䚷༤඾

་Ꮫ◊✲⛉

་Ꮫ

ᩍᤵ

ᒾ⏣䚷᝿

་Ꮫ◊✲⛉

་Ꮫ

ᩍᤵ



㔝⏣䚷ு

་Ꮫ◊✲⛉

་Ꮫ

ᩍᤵ

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ఀబ䚷ṇ

་Ꮫ◊✲⛉

་Ꮫ

ᩍᤵ



ᮌᮧ䚷๛

་Ꮫ◊✲⛉

་Ꮫ

ᩍᤵ

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ఀ㐩䚷ὒ⮳

་Ꮫ◊✲⛉

་Ꮫ

ᩍᤵ



ᐩᶔ䚷䛛䛚䜚

་Ꮫ◊✲⛉

་Ꮫ

ᩍᤵ



୍ᒣ䚷ᬛ

་Ꮫ◊✲⛉

་Ꮫ

ᩍᤵ



ᆏ஭䚷⩏἞

་Ꮫ◊✲⛉

་Ꮫ

ᩍᤵ



ᡞ஭䚷㞞࿴

་Ꮫ◊✲⛉

་Ꮫ

ᩍᤵ



ᑠᕝ䚷ಟ

་Ꮫ◊✲⛉

་Ꮫ

ᩍᤵ



㕥ᮌ䚷ⱱᙪ

་Ꮫ◊✲⛉

་Ꮫ

ᩍᤵ



ᯇ⏣䚷⚽୍

་Ꮫ◊✲⛉

་Ꮫ

ᩍᤵ



㧗ᶫ䚷Ⰻ㍜

་Ꮫ◊✲⛉

་Ꮫ

ᩍᤵ



ᐑᮏ䚷ா

་Ꮫ◊✲⛉

་Ꮫ

ᩍᤵ



ᑠᮡ䚷┾ྖ

་Ꮫ◊✲⛉

♫఍೺ᗣ་Ꮫ⣔

ᩍᤵ



๓ᕝ䚷ᖹ

་Ꮫ㒊㝃ᒓ⑓㝔㍺⾑⣽⬊἞⒪㒊

ᩍᤵ



㊊❧䚷ኋ୍

་Ꮫ◊✲⛉

ே㛫೺ᗣ⛉Ꮫ⣔

ᩍᤵ



᱇䚷ᩄᶞ

་Ꮫ◊✲⛉

ே㛫೺ᗣ⛉Ꮫ⣔

ᩍᤵ



ᮌୗ䚷ᙬᰤ

་Ꮫ◊✲⛉

ே㛫೺ᗣ⛉Ꮫ⣔

ᩍᤵ



᳝ྡ䚷Ẏ

་Ꮫ◊✲⛉

ே㛫೺ᗣ⛉Ꮫ⣔

ᩍᤵ



ᮡᮏ䚷┤୕

་Ꮫ◊✲⛉

ே㛫೺ᗣ⛉Ꮫ⣔

ᩍᤵ



㯮ᮌ䚷⿱ኈ

་Ꮫ◊✲⛉

ே㛫೺ᗣ⛉Ꮫ⣔

ᩍᤵ



ᕷᶫ䚷๎᫂

་Ꮫ◊✲⛉

ே㛫೺ᗣ⛉Ꮫ⣔

ᩍᤵ



஧ᮌ䚷ῄᏊ

་Ꮫ◊✲⛉

ே㛫೺ᗣ⛉Ꮫ⣔ᩍᤵ㻸㻵㻹㻿䝴䝙䝑䝖㛗ே㛫೺ᗣ⛉Ꮫ⣔ᑓᨷ㛗ྂ⏣䚷┿㔛ᯞ

་Ꮫ◊✲⛉ே㛫೺ᗣ⛉Ꮫ⣔

ᩍᤵ



୰㒊䚷୺ᩗ

ᕤᏛ◊✲⛉

ᶵᲔ⌮ᕤᏛ

ᩍᤵ



ᑠᑎ䚷⚽ಇ

ᕤᏛ◊✲⛉

䝬䜲䜽䝻䜶䞁䝆䝙䜰䝸䞁䜾

ᩍᤵ



⚄㔝䚷㑳ኵ

ᕤᏛ◊✲⛉

ཎᏊ᰾ᕤᏛ

ᩍᤵ



ᮌᮧ䚷ಇస

ᕤᏛ◊✲⛉

ᮦᩱ໬Ꮫ

ᩍᤵ



㏆⸨䚷㍤ᖾ

ᕤᏛ◊✲⛉

≀㉁䜶䝛䝹䜼䞊໬Ꮫ

ᩍᤵ



኱Ụ䚷ᾈ୍

ᕤᏛ◊✲⛉

≀㉁䜶䝛䝹䜼䞊໬Ꮫ

ᩍᤵ



ⓑᕝ䚷ᫀᏹ

ᕤᏛ◊✲⛉

ศᏊᕤᏛ

ᩍᤵ



⛅ྜྷ䚷୍ᡂ

ᕤᏛ◊✲⛉

㧗ศᏊ໬Ꮫ

ᩍᤵ



᳃䚷Ὀ⏕

ᕤᏛ◊✲⛉

ྜᡂ䞉⏕≀໬Ꮫ

ᩍᤵ



℈ᆅ䚷᱁

ᕤᏛ◊✲⛉

ྜᡂ䞉⏕≀໬Ꮫ

ᩍᤵ



኱ᔱ䚷ṇ⿱

ᕤᏛ◊✲⛉

໬ᏛᕤᏛ

ᩍᤵ



୰ᒣ䚷࿴ஂ

⸆Ꮫ◊✲⛉

⸆⛉Ꮫ

ᩍᤵ



㧘಴䚷႐ಙ

⸆Ꮫ◊✲⛉

⸆Ꮫ

ᩍᤵ



㔠Ꮚ䚷࿘ྖ

⸆Ꮫ◊✲⛉

⸆Ꮫ

ᩍᤵ



ຍ⸨䚷༤❶

⸆Ꮫ◊✲⛉

⸆⛉Ꮫ

ᩍᤵ



᥃㇂䚷⚽᫛

⸆Ꮫ◊✲⛉

་⸆๰ᡂ᝟ሗ⛉Ꮫ

ᩍᤵ



⏣⏿䚷Ὀᙪ

䜴䜲䝹䝇䞉෌⏕་⛉Ꮫ◊✲ᡤ

ᩍᤵ



Ᏻ㐩䚷Ὀ἞

䜴䜲䝹䝇䞉෌⏕་⛉Ꮫ◊✲ᡤᩍᤵᡞཱྀ⏣䚷῟ஓ

䜴䜲䝹䝇䞉෌⏕་⛉Ꮫ◊✲ᡤ

ᩍᤵ



℩ཎ䚷῟Ꮚ

䜴䜲䝹䝇䞉෌⏕་⛉Ꮫ◊✲ᡤ

ᩍᤵ



Ἑᮏ䚷ᏹ

䜴䜲䝹䝇䞉෌⏕་⛉Ꮫ◊✲ᡤ

ᩍᤵ



ᒣ⏣䚷㐨ኵ

ᩘ⌮ゎᯒ◊✲ᡤ

ᩍᤵ



ᑎす䚷㇏

་Ꮫ◊✲⛉



ᮌᮧ䚷♸

Ꮫ㝿⼥ྜᩍ⫱◊✲᥎㐍䝉䞁䝍䞊



㧘ᢡ䚷ᜤ୍

Ꮫ㝿⼥ྜᩍ⫱◊✲᥎㐍䝉䞁䝍䞊



す䚷⨾ᖾ

Ꮫ㝿⼥ྜᩍ⫱◊✲᥎㐍䝉䞁䝍䞊



ᯇᶫ䚷┾⏕

Ꮫ㝿⼥ྜᩍ⫱◊✲᥎㐍䝉䞁䝍䞊㧗ᶫ䚷䜑䛔Ꮚ

Ꮫ㝿⼥ྜᩍ⫱◊✲᥎㐍䝉䞁䝍䞊



ᮾ᳃䚷ಙᑵ

Ꮫ㝿⼥ྜᩍ⫱◊✲᥎㐍䝉䞁䝍䞊ᵽཱྀ䚷䜖䜚Ꮚ

⸆Ꮫ◊✲⛉

⸆Ꮫ



ᚋ⸨䚷ບ

៞᠕⩏ሿ኱Ꮫ

⤒Ⴀ⟶⌮◊✲⛉

䛂་Ꮫ㡿ᇦ䛃⏘Ꮫ㐃ᦠ᥎㐍ᶵᵓ೺ᗣ㛗ᑑ♫఍䛾⥲ྜ་⒪㛤Ⓨ䝴䝙䝑䝖೺ᗣ㛗ᑑ♫఍䛾⥲ྜ་⒪㛤Ⓨ䝴䝙䝑䝖೺ᗣ㛗ᑑ♫఍䛾⥲ྜ་⒪㛤Ⓨ䝴䝙䝑䝖೺ᗣ㛗ᑑ♫఍䛾⥲ྜ་⒪㛤Ⓨ䝴䝙䝑䝖೺ᗣ㛗ᑑ♫఍䛾⥲ྜ་⒪㛤Ⓨ䝴䝙䝑䝖೺ᗣ㛗ᑑ♫఍䛾⥲ྜ་⒪㛤Ⓨ䝴䝙䝑䝖

≉௵ᩍᤵ
≉ᐃ෸ᩍᤵ
≉ᐃ෸ᩍᤵ
≉ᐃ෸ᩍᤵ
≉ᐃ෸ᩍᤵ
≉ᐃㅮᖌ
≉ᐃㅮᖌ
ㅮᖌ

⸆Ꮫ◊✲⛉㛗

≉ᐃᩍဨ୍ぴᖹᡂ㻟㻜ᖺ㻟᭶㻟㻝᪥⌧ᅾ

Ặ䚷䚷ྡ
㻝

䜻䝮䝷

䝴䜴

㻞

䝍䜹 䜸䝸

䜻䝵䜴䜲䝏

㻟

䝙䝅

㻠

䝬䝒䝝䝅

䝬䝃䜸

㻡

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㑇ఏ་Ꮫㅮᗙᨺᑕ⥺㑇ఏᏛච␿䝀䝜䝮་Ꮫㅮᗙ

㻺㼍㼖㼚㼕㼚㻌㻾㼕㼒㼍㼠㻌㻭㼞㼍㻰䠟䠍㑇ఏ་Ꮫㅮᗙᨺᑕ⥺㑇ఏᏛ㻾㼑㼢㼑㼍㼘㼕㼚㼓㻌㼠㼔㼑㻌㼞㼛㼘㼑㻌㼛㼒㻌㻭㼀㻹㻌㼗㼕㼚㼍㼟㼑㻌㼕㼚㻌㼞㼑㼙㼛㼢㼍㼘㻌㼛㼒㻌㼜㼍㼠㼔㼛㼘㼛㼓㼕㼏㼍㼘㼠㼛㼜㼛㼕㼟㼛㼙㼑㼞㼍㼟㼑㻌㼏㼘㼑㼍㼢㼍㼓㼑㻌㼏㼛㼙㼜㼘㼑㼤㻌㻔㼀㻻㻼㻞㼏㼏㻕㻌㼍㼐㼐㼡㼏㼠㻚㻰㼑㼢㼑㼘㼛㼜㼕㼚㼓㻌㻯㼛㼙㼜㼡㼠㼍㼠㼕㼛㼚㼍㼘㻌㻳㼑㼚㼛㼠㼛㼤㼕㼏㼕㼠㼥㻌㻭㼟㼟㼍㼥㻌㼀㼛㼛㼘㼟㻦㻌㻭㼚㻌㼕㼚㼟㼕㼘㼕㼏㼛㻌㼍㼜㼜㼞㼛㼍㼏㼔䛜䜣ᢚไ㑇ఏᏊ㻮㻾㻯㻭䠍䛾᪂ᶵ⬟䛻╔┠䛧䛯䚸೺ᖖዪᛶ⏤᮶㻮㻾㻯㻭㻝䛾Ⅼኚ␗䛛䜙Ⓨ䛜䜣ᛶ䜢ண 䛩䜛ᡭἲ䛾㛤Ⓨ㻰㼑㼢㼑㼘㼛㼜㼙㼑㼚㼠㻌㼛㼒㻌㼍㻌㼜㼞㼑㼐㼕㼏㼠㼕㼛㼚㻌㼙㼑㼠㼔㼛㼐㻌㼒㼛㼞㻌㼏㼍㼞㼏㼕㼚㼛㼓㼑㼚㼕㼏㼕㼠㼥㻌㼒㼞㼛㼙㼜㼛㼕㼚㼠㻌㼙㼡㼠㼍㼠㼕㼛㼚㻌㼛㼒㻌㻮㻾㻯㻭㻝㻌㼣㼔㼕㼏㼔㻌㼐㼑㼞㼕㼢㼑㼐㻌㼒㼞㼛㼙㻌㼔㼑㼍㼘㼠㼔㼥㻌㼣㼛㼙㼍㼚㼎㼍㼟㼑㼐㻌㼛㼚㻌㼚㼑㼣㻌㼒㼡㼚㼏㼠㼕㼛㼚㼟㻌㼛㼒㻌㼠㼡㼙㼛㼞㻌㼟㼡㼜㼜㼞㼑㼟㼟㼛㼞㻌㼓㼑㼚㼑㻘㻌㻮㻾㻯㻭㻝㼜㻴ᛂ⟅ᛶ㏆㉥እ䝅䜰䝙䞁Ⰽ⣲䜢⏝䛔䛯㧗䝁䞁䝖䝷䝇䝖䛺⭘⒆㐀ᙳ๣䛾㛤Ⓨ㻰㼑㼢㼑㼘㼛㼜㼙㼑㼚㼠㻌㼛㼒㻌㼔㼕㼓㼔㻙㼏㼛㼚㼠㼞㼍㼟㼠㻌㼠㼡㼙㼛㼞㻌㼕㼙㼍㼓㼕㼚㼓㻌㼍㼓㼑㼚㼠㻌㼡㼟㼕㼚㼓㻌㼜㻴㻙㼞㼑㼟㼜㼛㼚㼟㼕㼢㼑㻌㼚㼑㼍㼞㻙㼕㼚㼒㼞㼍㼞㼑㼐㻌㼏㼥㼍㼚㼕㼚㼑㻌㼐㼥㼑ど஺ཫୖ᰾䝅䜾䝘䝹ศᏊ䛾ゎ᫂䛻䜘䜛᫬ᕪ⑕ೃ⩌䛾๰⸆◊✲㻰㼕㼟㼏㼛㼢㼑㼞㼥㻌㼛㼒㻌㼟㼕㼓㼚㼍㼘㼕㼚㼓㻌㼙㼛㼘㼑㼏㼡㼘㼑㼟㻌㼕㼚㻌㼠㼔㼑㻌㼟㼡㼜㼞㼍㼏㼔㼕㼍㼟㼙㼍㼠㼕㼏㼚㼡㼏㼘㼑㼡㼟㻌㼠㼛㻌㼐㼑㼢㼑㼘㼛㼜㻌㼠㼔㼑㻌㼐㼞㼡㼓㻌㼒㼛㼞㻌㼖㼑㼠㻌㼘㼍㼓య ᇦ䛾 ᗘኚ໬䛻䜘䜛⏕య䝸䝈䝮ไᚚ䛾ゎ᫂㻱㼒㼒㼑㼏㼠㻌㼛㼒㻌㼜㼔㼥㼟㼕㼛㼘㼛㼓㼕㼏㼍㼘㻌㼠㼑㼙㼜㼑㼞㼍㼠㼡㼞㼑㻌㼏㼔㼍㼚㼓㼑㻌㼛㼚㻌㼏㼕㼞㼏㼍㼐㼕㼍㼚㼏㼘㼛㼏㼗㻌㼕㼚㻌㼙㼍㼙㼙㼍㼘㻝㻚㻾㼁㻺㼄㻞ไᚚ䛻䜘䜛ཤໃ᢬ᢠᛶ⚄⤒ෆศἪᛶ๓❧⭢⒴䛻ᑐ䛩䜛἞⒪㻞㻚㻾㼁㻺㼄㻝ไᚚ䛻䜘䜛㧊ⱆ⭘䛻ᑐ䛩䜛἞⒪㻝㻚㻳㼑㼚㼑㼠㼕㼏㻌㼞㼑㼓㼡㼘㼍㼠㼕㼛㼚㻌㼛㼒㻌㻾㼁㻺㼄㻞㻌㼔㼍㼟㻌㼍㼚㼠㼕㼠㼡㼙㼛㼞㻌㼑㼒㼒㼑㼏㼠㼟㻌㼛㼚㼏㼍㼟㼠㼞㼍㼠㼕㼛㼚㻙㼞㼑㼟㼕㼟㼠㼍㼚㼠㻌㼚㼑㼡㼞㼛㼑㼚㼐㼛㼏㼞㼕㼚㼑㻌㼜㼞㼛㼟㼠㼍㼠㼑㼏㼍㼚㼏㼑㼞㻚㻞㻚㻳㼑㼚㼑㼠㼕㼏㻌㼞㼑㼓㼡㼘㼍㼠㼕㼛㼚㻌㼛㼒㻌㻾㼁㻺㼄㻝㻌㼔㼍㼟㻌㼍㼚㼠㼕㼠㼡㼙㼛㼞㻌㼑㼒㼒㼑㼏㼠㼟㼛㼚㻌㼙㼑㼐㼡㼘㼘㼛㼎㼘㼍㼟㼠㼛㼙㼍䝝䞁䝗䝦䝹䝗ᆺ䝥䝻䞊䝤䜢⏝䛔䛯⏕యග㡢㡪⏬ീ䛾㧗⏬㉁໬
෌ᵓᡂἲ䛾᳨ウ㻱㼤㼍㼙㼕㼚㼍㼠㼕㼛㼚㻌㼒㼛㼞㻌㼞㼑㼏㼛㼚㼟㼠㼞㼡㼏㼠㼕㼚㼓㻌㼔㼕㼓㼔㻌㼝㼡㼍㼘㼕㼠㼥㻌㼎㼕㼛㼘㼛㼓㼕㼏㼍㼘㼜㼔㼛㼠㼛㼍㼏㼛㼡㼟㼠㼕㼏㻌㼕㼙㼍㼓㼑㻌㼡㼟㼕㼚㼓㻌㼔㼍㼚㼐㼔㼑㼘㼐㻌㼟㼥㼟㼠㼑㼙㻸㻵㻹㻿◊✲䝔䞊䝬㻾㼍㼚㼐㼛㼘㼜㼔㻌㻿㼍㼗㼕㻾㼡㼕㼦㻌㻾㼛㼐㼞㼕㼓㼡㼑㼦㻰㼍㼚㼕㼑㼘㼍

㻿㼍㼞㼏㼍㻌㻭㼚㼍㼙㼍㼞㼕㼍㼀㼔㼕㼞㼍㼚㼡㼠

㻶㼍㼞㼛㼛㼚㼣㼕㼠㼏㼔㼍㼣㼍㼚㻱㼘㼡㼏㼕㼐㼍㼠㼕㼛㼚㻌㼛㼒㻌㼠㼔㼑㻌㼞㼛㼘㼑㻌㼛㼒㻌㼙㼕㼏㼞㼛㻾㻺㻭㻙㻟㻟㼍㻛㼎㻌㼕㼚㻌㼘㼥㼙㼜㼔㼑㼐㼑㼙㼍㻚⺯ගඹ㬆䜶䝛䝹䜼䞊⛣ືཎ⌮䜢ᛂ⏝䛧䛯䝺䝖䝻䜴䜲䝹䝇ྍど໬ᢏ⾡䛾ᶞ❧ཬ䜃䛭䛾ᛂ⏝㻰㼑㼢㼑㼘㼛㼜㼙㼑㼚㼠㻌㼛㼒㻌㼍㻌㼞㼑㼠㼞㼛㼢㼕㼞㼡㼟㻌㼢㼕㼟㼡㼍㼘㼕㼦㼍㼠㼕㼛㼚㻌㼠㼑㼏㼔㼚㼛㼘㼛㼓㼥㻌㼎㼍㼟㼑㼐㼛㼚㻌㼠㼔㼑㻌㻲㻾㻱㼀㻌㼜㼞㼕㼚㼏㼕㼜㼘㼑㻌㼍㼚㼐㻌㼕㼠㼟㻌㼜㼛㼠㼑㼚㼠㼕㼍㼘㻌㼍㼜㼜㼘㼕㼏㼍㼠㼕㼛㼚㼟㻾㼑㼓㼡㼘㼍㼠㼕㼛㼚㻌㼛㼒㻌㻳㼑㼚㼛㼙㼕㼏㻌㻵㼚㼟㼠㼍㼎㼕㼘㼕㼠㼥㻌㼕㼚㻌㻭㼏㼠㼕㼢㼍㼠㼑㼐㻌㻮㻌㼏㼑㼘㼘㼟㻚㻵㼚㼢㼑㼟㼠㼕㼓㼍㼠㼕㼛㼚㻌㼛㼒㻌㼒㼍㼏㼠㼛㼞㼟㻌㼕㼚㼢㼛㼘㼑㼐㻌㼕㼚㻌㼓㼑㼚㼛㼙㼕㼏㻌㼕㼚㼟㼠㼍㼎㼕㼘㼕㼠㼥㻌㼕㼚㻹㼍㼔㼙㼡㼐㻌㻹㼐㻌㻾㼍㼟㼑㼘㻌㻭㼘 㼙㼍㼙㼙㼍㼘㼕㼍㼚㻌㼏㼑㼘㼘㼟㻌㼍㼚㼐㻌㼙㼕㼏㼑㻌㼙㼛㼐㼑㼘㻚㻼㼛㼘㼍㼟㼔㻌㻭㼔㼟㼍㼚㻌㻴㼍㼎㼕㼎㻰䠟䠍㑇ఏ་Ꮫㅮᗙᨺᑕ⥺㑇
ఏᏛ

䝘䜸䝖

ΎỈ䚷┤Ⓩ

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䜸䜶

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๓ᕝ䚷ὒኴ

䝬䜶䜹䝽

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Ặྡ

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Ꮫᖺ

㑇ఏ་Ꮫㅮᗙᨺᑕ⥺㑇
ఏᏛ

ே
㛫
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⛉๰
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᝟
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⛉๰
㔝
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᝟
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㉁
䜶 ᇶ♏≀㉁໬Ꮫㅮᗙ
໬
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Ꮫ
䝹

ᑓᨷ

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◊✲
⛉

ᖹᡂ䠎䠕ᖺᗘ䠄㻌䠨䠍㻌䠅䚷㻸㻵㻹㻿ᒚಟ⪅䞉ᣦᑟᩍᤵ䞉䝯䞁䝍䞊୍ぴ

呎

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䝍䜿䝅

་Ꮫ◊✲⛉䚷ෆ⛉Ꮫㅮᗙᚠ⎔ჾෆ⛉Ꮫ

ᮌᮧ䚷๛䚷ᩍᤵ

䜻䝮䝷་Ꮫ◊✲⛉䚷ෆ⛉Ꮫㅮᗙ⾑ᾮ䞉⭘⒆ෆ⛉Ꮫ䜰䜻䝣䝭㧗ᢡ䚷᫭ྐ䚷ᩍᤵ་Ꮫ◊✲⛉䚷⬻⑓ែ⏕⌮Ꮫㅮᗙ⮫ᗋ⚄⤒Ꮫ㧘ᶫ䚷Ⰻ㍜䚷ᩍᤵ䝍䜹䝝䝅䚷㻌䝸䝵䜴䝇䜿་Ꮫ◊✲⛉䚷㑇ఏ་Ꮫㅮᗙ
ᨺᑕ⥺㑇ఏᏛ

Ṋ⏣䚷ಇ୍䚷ᩍᤵ䝍䜿䝎䚷䚷䝅䝳䞁䜲䝏෌⏕་⛉Ꮫ◊✲ᡤ㻌෌⏕⤫ᚚᏛ◊✲㒊㛛㻌෌⏕ච␿Ꮫ

䜹䝽䝰䝖་Ꮫ◊✲⛉䚷ᐤ㝃ㅮᗙච␿䝀䝜䝮་Ꮫ
䝍䜹䜸䝸

䝇䝈䜻

䜹䝈䜻

䜻䝵䜴䜲䝏

䝴䜴

䝬䝃䜸

䝭䝴䜻

䝙䝅

䝭䝴䜻

す䚷⨾ᖾ䚷≉ᐃ෸ᩍᤵᕤᏛ◊✲⛉㻌ศᏊ⏕≀໬Ꮫศ㔝㻌䠄᳃◊✲ᐊ䠅䛆ᖖ໅ඛ䠖㻌⸆Ꮫ◊✲⛉㻌⏕యศᏊㄆ㆑Ꮫ㻌䠄➉ᓥ
◊✲ᐊ䠅䛇

䝙䝅

す䚷⨾ᖾ䚷≉ᐃ෸ᩍᤵ་Ꮫ◊✲⛉䚷⬻ᶵ⬟⥲ྜ◊✲䝉䞁䝍䞊䝬䝃䜸ᯇᶫ䚷┾⏕䚷≉ᐃ෸ᩍᤵ䝬䝒䝝䝅་Ꮫ◊✲⛉䚷⬻ᶵ⬟⥲ྜ◊✲䝉䞁䝍䞊䝬䝒䝝䝅ᯇᶫ䚷┾⏕䚷≉ᐃ෸ᩍᤵ་Ꮫ◊✲⛉䚷⬻ᶵ⬟⥲ྜ◊✲䝉䞁䝍䞊䝘䜸䝲኱▼䚷┤ஓ䚷≉ᐃㅮᖌ䜸䜸䜲䝅ᕤᏛ◊✲⛉䚷≀㉁䜶䝛䝹䜼䞊໬Ꮫᑓᨷඛ➃་ᕤᏛศ㔝䠄᱇䜻䝱䞁䝟䝇㻭䜽䝷䝇䝍䞊䚷㏆⸨◊✲ᐊ䠅䜻䝮䝷ᮌᮧ䚷♸䚷≉ᐃ෸ᩍᤵ་Ꮫ◊✲⛉䚷⫢⫹⮅䞉⛣᳜እ⛉Ꮫ䚷䠄ୖᮏ◊✲ᐊ䠅䝍䜹䜸䝸㧘ᢡ䚷ᜤ୍䚷≉ᐃ෸ᩍᤵ⸆Ꮫ◊✲⛉䚷⏕యᶵ⬟ゎᯒᏛศ㔝䠄㔠Ꮚ◊✲ᐊ䠅䝘䜺䝲䝇ỌᏳ䚷୍ᶞ䚷≉ᐃຓᩍ་Ꮫ◊✲⛉䚷⬻ᶵ⬟⥲ྜ◊✲䝉䞁䝍䞊䝍䜹䝅㕥ᮌ䚷ᓫኈ䚷≉ᐃຓᩍ䝯䞁䝍䞊㻞㻜㻝㻣㻚㻝㻜㻚㻝

䝭䝴䜻

䝜䝤䝴䜻

᝟ሗᏛ◊✲⛉䚷ᛂ⏝ゎᯒᏛㅮᗙ䠄☾◊✲ᐊ䠅

䝠䜺䝅䝰䝸ᮾ᳃䚷ಙᑵ䚷≉ᐃㅮᖌ་Ꮫ◊✲⛉䚷㝃ᒓ䝀䝜䝮་Ꮫ䝉䞁䝍䞊⑌ᝈ䝀䝜䝮␿Ꮫゎᯒศ㔝㻌㻔ᯇ⏣◊✲ᐊ㻕䝯䜲䝁㧗ᶫ䚷䜑䛔Ꮚ䚷≉ᐃㅮᖌ䝍䜹䝝䝅ᕤᏛ◊✲⛉㻌ศᏊ⏕≀໬Ꮫศ㔝㻌䠄᳃◊✲ᐊ䠅䛆ᖖ໅ඛ䠖㻌⸆Ꮫ◊✲⛉㻌⏕యศᏊㄆ㆑Ꮫ㻌䠄➉ᓥ
◊✲ᐊ䠅䛇

䝙䝅

す䚷⨾ᖾ䚷≉ᐃ෸ᩍᤵ⸆Ꮫ◊✲⛉་⸆๰ᡂ᝟ሗ⛉Ꮫᑓᨷ䚷་⸆๰ ᕤᏛ◊✲⛉㻌ศᏊ⏕≀໬Ꮫศ㔝㻌䠄᳃◊✲ᐊ䠅ᡂ᝟ሗ⛉Ꮫㅮᗙ䡸䡹䡿䢍䡵䢏䡺䢓䢇䢛䡬 ไᚚศᏊ 䛆ᖖ໅ඛ䠖㻌⸆Ꮫ◊✲⛉㻌⏕యศᏊㄆ㆑Ꮫ㻌䠄➉ᓥ◊✲ᐊ䠅䛇Ꮫ᥃㇂䚷⚽᫛䚷ᩍᤵ䜹䜿䝲䚷䚷䝠䝕䜰䜻་Ꮫ◊✲⛉䚷⏕యᵓ㐀་Ꮫㅮᗙᶵ⬟ᚤ⣽ᙧែᏛ

䝃䜲䝖䜴ᩪ⸨䚷㏻⣖䚷ᩍᤵ་Ꮫ◊✲⛉䚷⏕యᵓ㐀་ᏛㅮᗙᙧែᙧᡂᶵᵓᏛ

䝝䜼䝽䝷ⴗཎ䚷ṇᩄ䚷ᩍᤵ་Ꮫ◊✲⛉䚷ศᏊ⏕య⤫ᚚᏛㅮᗙศᏊ⭘⒆Ꮫ

䝜䝎䚷䚷䚷䚷䚷䝬䝁䝖㔝⏣䚷ு䚷ᩍᤵ

ᕤᏛ◊✲⛉䚷㧗ศᏊ໬Ꮫᑓᨷ
㧗ศᏊ≀ᛶㅮᗙ⏕యᶵ⬟㧗ศᏊศ㔝䜹䝈䝘䝸⛅ྜྷ䚷୍ᡂ䚷ᩍᤵ䜰䜻䝶䝅་Ꮫ◊✲⛉䚷⏕య᝟ሗ⛉Ꮫㅮᗙ⏕య᝟ሗ⛉Ꮫ

䝽䝍䝘䝧䚷䚷䝎䜲

Ώ㑓䚷኱䚷ᩍᤵ

་Ꮫ◊✲⛉䚷㧗ḟ⬻⛉Ꮫㅮᗙ
⚄⤒⏕≀Ꮫ

䜲䝃

ఀబ䚷ṇ䚷ᩍᤵ

Ἑᮏ䚷㻌ᏹ䚷ᩍᤵ䝍䝇䜽䝇䝇䝮་Ꮫ◊✲⛉䚷⬻⑓ែ⏕⌮Ꮫㅮᗙ⬻⚄⤒እ⛉Ꮫ

䝭䝲䝰䝖ᐑᮏ䚷ா䚷ᩍᤵ

་Ꮫ◊✲⛉䚷ே㛫೺ᗣ⛉Ꮫ⣔ᑓᨷ᳨ᰝᢏ⾡⛉Ꮫ䝁䞊䝇䚷᝟ሗ⌮ᕤ་⒪Ꮫㅮᗙඛ㐍་⒪ᶵჾ㛤ⓎᏛ䝘䜸䝌䜴ᮡᮏ䚷┤୕䚷ᩍᤵ䝇䜼䝰䝖㻸㻵㻹㻿ᣦᑟᩍᤵ

ᮏᗢ䚷భ䚷ᐈဨᩍᤵ

䝩䞁䝆䝵་Ꮫ◊✲⛉䚷㑇ఏ་Ꮫㅮᗙ
ᨺᑕ⥺㑇ఏᏛ

Ṋ⏣䚷ಇ୍䚷ᩍᤵ䝍䜿䝎䚷䚷䝅䝳䞁䜲䝏་Ꮫ◊✲⛉䚷㑇ఏ་Ꮫㅮᗙ
ᨺᑕ⥺㑇ఏᏛ

Ṋ⏣䚷ಇ୍䚷ᩍᤵ䝍䜿䝎䚷䚷䝅䝳䞁䜲䝏་Ꮫ◊✲⛉䚷㑇ఏ་Ꮫㅮᗙ
ᨺᑕ⥺㑇ఏᏛ

Ṋ⏣䚷ಇ୍䚷ᩍᤵ䝍䜿䝎䚷䚷䝅䝳䞁䜲䝏་Ꮫ◊✲⛉䚷㑇ఏ་Ꮫㅮᗙ
ᨺᑕ⥺㑇ఏᏛ

Ṋ⏣䚷ಇ୍䚷ᩍᤵ䝍䜿䝎䚷䚷䝅䝳䞁䜲䝏ᕤᏛ◊✲⛉䚷≀㉁䜶䝛䝹䜼䞊໬Ꮫᑓᨷᇶ♏≀㉁໬Ꮫㅮᗙ

䝁䜴䜲䝏኱Ụ䚷ᾈ୍䚷ᩍᤵ䜸䜸䜶⸆Ꮫ◊✲⛉䚷་⸆๰ᡂ᝟ሗ⛉Ꮫᑓᨷ་⸆๰ᡂ᝟ሗ⛉Ꮫㅮᗙ䝅䝇䝔䝮䝞䜲䜸䝻䝆䞊ศ㔝䝠䝖䝅ᒸᮧ䚷ᆒ䚷ᩍᤵ

䜸䜹䝮䝷⸆Ꮫ◊✲⛉䚷་⸆๰ᡂ᝟ሗ⛉Ꮫᑓᨷ་⸆๰ᡂ᝟ሗ⛉Ꮫㅮᗙ䝅䝇䝔䝮䝞䜲䜸䝻䝆䞊ศ㔝ᒸᮧ䚷ᆒ䚷ᩍᤵ

䜸䜹䝮䝷་Ꮫ◊✲⛉䚷ே㛫೺ᗣ⛉Ꮫ⣔ᑓᨷ᳨ᰝᢏ⾡⛉Ꮫ䝁䞊䝇䚷་⒪᳨ᰝᒎ㛤Ꮫㅮᗙ᳨ᰝᛂ⏝㛤ⓎᏛ䝲䝇䝠䝁ୖஂಖ䚷㟹ᙪ䚷෸ᩍᤵ䜹䝭 䜽䝪་Ꮫ◊✲⛉䚷ே㛫೺ᗣ⛉Ꮫ⣔ᑓᨷ᳨ᰝᢏ⾡⛉Ꮫ䝁䞊䝇䚷᝟ሗ⌮ᕤ་⒪Ꮫㅮᗙ
་⒪⏬ീ᝟ሗ䝅䝇䝔䝮Ꮫ䝒䝶䝅᳝ྡ䚷Ẏ䚷ᩍᤵ

䝅䜲䝘ᣦᑟᩍᤵ䈜䝯䞁䝍䞊䛻䛴䛔䛶䚷㻌ୖẁ䠖ྡ๓䚷䚷ୗẁ䠖໅ົሙᡤ
࣓ͤࣥࢱ࣮࡟ࡘ࠸࡚
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⸆ ⑓యᶵ⬟ゎᯒᏛㅮᗙᏛ ⏕యᶵ⬟ゎᯒᏛ

䝠䜺䝅䝰䝸

䝜䝤䝴䜻

ᮾ᳃ࠉಙᑵࠉ≉ᐃㅮᖌ་Ꮫ◊✲⛉ࠉே㛫೺ᗣ⛉Ꮫ⣔ᑓᨷ᳨ᰝᢏ⾡⛉Ꮫࢥ࣮ࢫࠉ᝟ሗ⌮ᕤ་⒪Ꮫㅮᗙ
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䝘䜸䝌䜴ᮡᮏࠉ┤୕ࠉᩍᤵ

䝅䜲䝘

䝒䝶䝅

䝣䝆䝰䝖

䝁䜴䝆

᳝ྡࠉẎࠉᩍᤵ

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ᩘ⌮ゎᯒ◊✲ᡤᩘᏛ࣭ᩘ⌮ゎᯒᑓᨷᩘ⌮ゎᯒ⣔

་Ꮫ◊✲⛉⬻ᶵ⬟⥲ྜ◊✲䝉䞁䝍䞊

䜹䝭 䜽䝪

䝲䝇䝠䝁

䝍䝞䝍䚷䚷㻌䝲䝇䝠䝁

䝇䝈䜻

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䜰䜹䜺䝽

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䝍䜹䜸䝸

䜻䝵䜴䜲䝏

㧘ᢡ䚷ᜤ୍䚷≉ᐃ෸ᩍᤵ⸆Ꮫ◊✲⛉ࠉ་⸆๰ᡂ᝟ሗ⛉Ꮫᑓᨷ་⸆๰ᡂ᝟ሗ⛉Ꮫㅮᗙࢩࢫࢸ࣒ࣂ࢖࢜ࣟࢪ࣮ศ㔝་Ꮫ◊✲⛉ࠉᇶ♏⑓ែᏛㅮᗙ
⑓ែ⏕≀་Ꮫ

་Ꮫ◊✲⛉⫢⫹⮅࣭⛣᳜እ⛉Ꮫࠉ㸦ୖᮏ◊✲ᐊ㸧䝏䝳䜴䝆䝵䜴䚷䝶䝅䜻䝰䝸䚷䚷䚷䝲䝇䜸

䝇䝈䜻䝍䜹䝅୰ᲄࠉၿᶞࠉᩍᤵ

᳃ࠉὈ⏕ࠉᩍᤵ

㕥ᮌ䚷ᓫኈ䚷≉ᐃຓᩍ

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䜹䜿䝲䚷䚷䝠䝕䜰䜻

䝍䜹䝝䝅

䝯䜲䝁

᥃㇂ࠉ⚽᫛ࠉᩍᤵ

㧗ᶫࠉࡵ࠸Ꮚࠉ≉ᐃㅮᖌ

7KHGHYHORSPHQWRILQVLOLFRDSSURDFKEDVHGRQ
WKHH[SUHVVLRQOHYHORIKRPRORJRXVUHFRPELQDWLRQIDFWRUVWRSUHGLFWFDQFHUWKHUDS\HIIHFW་Ꮫ◊✲⛉ࠉ㑇ఏ་Ꮫㅮᗙ
ᨺᑕ⥺㑇ఏᏛ

⸆Ꮫ◊✲⛉་⸆๰ᡂ᝟ሗ⛉Ꮫᑓᨷࠉ་
⸆๰ᡂ᝟ሗ⛉Ꮫㅮᗙ㺚㺛㺡㺯㺗㺱㺜㺵㺩㺽㺎 ไᚚ
ศᏊᏛ

་Ꮫ◊✲⛉
㝃ᒓࢤࣀ࣒་Ꮫࢭࣥࢱ࣮
⑌ᝈࢤࣀ࣒␿Ꮫゎᯒศ㔝ᯇ⏣◊✲ᐊ䝜䝎䚷䚷䚷䝬䝁䝖

䝕䜱䞁䚷㻌㻌㻌㻌䝝㻌㻌㻌㻌㻌䝴䜱䚷㻌㻌㻌㻌䝔䜱Ṋ⏣ࠉಇ୍ࠉᩍᤵ

㔝⏣䚷ு䚷ᩍᤵ

'LQK+D'X\7KX\ࠉ◊✲ဨ་Ꮫ◊✲⛉ࠉ㑇ఏ་Ꮫㅮᗙ
ᨺᑕ⥺㑇ఏᏛ

་Ꮫ◊✲⛉䚷ศᏊ⏕య⤫ᚚᏛㅮᗙ
ศᏊ⭘⒆Ꮫ

་Ꮫ◊✲⛉
⬻ᶵ⬟⥲ྜ◊✲ࢭࣥࢱ࣮'HYHORSPHQWRIWKHPHWKRGRISUHGLFWLQJWKH
RQFRJHQLFSRWHQWLDORIPXWDWLRQVIRXQGLQWKH%5&$JHQHLQKHDOWK\IHPDOHV

䝉 䝝䝷

䜰䝒䝁

䝃䜲䝖䜴

䝭䝏䝜䝸

䜸䜹䝎

䝖䝰䝠䝃

℩ཎࠉ῟Ꮚࠉᩍᤵ

ᩪ⸨ࠉ㏻⣖ࠉᩍᤵ

ᒸ⏣䚷▱ஂ䚷≉ᐃ෸ᩍᤵ෌⏕་⛉Ꮫ◊✲ᡤ෌⏕⤫ᚚᏛ◊✲㒊㛛෌⏕ቑṪไᚚᏛ

་Ꮫ◊✲⛉ࠉ⏕యᵓ㐀་Ꮫㅮᗙᶵ⬟ᚤ⣽ᙧែᏛ

་Ꮫ◊✲⛉⬻ᶵ⬟⥲ྜ◊✲䝉䞁䝍䞊

䝅

⋤ࠉᱻ

䝘䜺䝅䝬

䝭䝏䝴䜻

ᯇ⏣ࠉ㐨⾜ࠉᩍᤵ

䝭

㉥ᕝࠉ♩⨾

䜰䜽䝍䞊

䝬䝒䝎

ᒸᮧࠉᆒࠉᩍᤵ

䝝䝲䝖

ᡂΎࠉ㣁ᩯ

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䜹ᑠᓥࠉⳀᯝࢮࣈࣛࣇ࢕ࢵࢩࣗࢆ⏝࠸ࡓຍ㱋࡟క࠺➽ⴎ⦰ࡢศᏊ࣓࢝ࢽࢬ࣒ࡢゎ᫂䜰䝎䝏᳝ྡࠉẎࠉᩍᤵ

䝍䜿䝎䚷䚷䚷䝅䝳䞁䜲䝏



䝘䜸䝲

䝅䞁䝍䝻䜴

ࡀࢇ⣽⬊࡟࠾ࡅࡿ┦ྠ⤌᥮࠼ᅉᏊࡢⓎ⌧ࣞ࣋ࣝࢆᇶ࡟ࡋࡓࠊᝈ⪅ẖࡢࡀࢇ἞⒪ຠᯝண ἲࡢ㛤
Ⓨ


䜸䜸䜲䝅

኱▼䚷┤ஓ䚷≉ᐃㅮᖌ

䜸䜹䝮䝷

᝟་
⸆ ሗ ⸆ ࢩࢫࢸ࣒ࣂ࢖࢜ࣟࢪ࣮Ꮫ ⛉ ๰ ศ㔝
Ꮫᡂ

䝠䝻䝅

䝭䝃䜻

すᒣࠉ⨾ဏ

䝬䜶䝎

䜹䝽䝰䝖

Ἑᮏࠉᏹࠉᩍᤵ

䜲䜸䝸

ᑎ⏣ࠉఀ⧊

䝙䝅䝲䝬

䝋䜴䜲䝏

㊊❧ኋ୍ࠉᩍᤵ

䝅䜲䝘

ே
⛉
་
㛫

Ꮫ ᝟ሗ⌮ᕤ་⒪ᏛㅮᗙᏛ೺⣔ᗣ䝕䜱䞁䚷㻌㻌㻌㻌䝝㻌㻌㻌㻌㻌䝴䜱䚷㻌㻌㻌㻌䝔䜱℈ᆅࠉࠉ᱁ࠉᩍᤵ

䝲䝇 䝘䝸

㧗ᒣࠉ⿱ᡂ

䝔䝷䝎

䜲䝍䝹

ୖᮡࠉᚿᡂࠉᩍᤵ

䝇䜼䝰䝖

ே
⛉
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㛫 ඛ㐍་⒪ᶵჾ㛤ⓎᏛศ

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ᗣ

䝝䝬䝏

࣓ࣥࢱ࣮

䜿䞁䝅䝵䜴

㕥ᮌࠉ೺⪷

䝍䜹䝲䝬

䜴䜶䝇䜼䚷䚷䝰䝖䝘䝸䚷/,06ᣦᑟᩍᤵ

䝝䝲䝉

⛗㇂ࠉ㞙ୡ

䝇䝈䜻

◊✲⛉ᣦᑟᩍᤵ

䜹䝛䝁

䝅䝳䜴䝆

䝬䝒䝎

䝅䝳䜴䜲䝏

䝠䜺䝅䝰䝸

䝜䝤䝴䜻

㔠Ꮚࠉ࿘ྖࠉᩍᤵ

ᯇ⏣ࠉ⚽୍ࠉᩍᤵ

ᮾ᳃䚷ಙᑵ䚷≉ᐃㅮᖌ⸆Ꮫ◊✲⛉ࠉ⸆Ꮫᑓᨷ
⑓ែᶵ⬟ゎᯒᏛㅮᗙ
⏕యᶵ⬟ゎᯒᏛศ㔝་Ꮫ◊✲⛉ឤぬ㐠ື⣔እ⛉Ꮫㅮᗙᩚᙧእ⛉Ꮫ᝟ሗᏛ◊✲⛉ࠉᛂ⏝ゎᯒᏛㅮᗙ㸦☾◊✲ᐊ㸧

䝍䜽䝲㛗ᓥࠉ༟ஓ

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SUHGLFWLRQRIWKHULVNIDFWRUVIRUGUXJ VVLGH
HIIHFWVXVLQJDGYHUVHGUXJHYHQWGDWDEDVH)$(56

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◊✲
ᑓᨷ
⛉

ศ㔝➼

་
་
⛉ ᨺᑕ⥺㑇ఏᏛ

Ꮫ
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

་
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⛉ ⮫ᗋ⚄⤒ᏛᏛᏛẶྡ䝷䞊䝬䞁䚷䚷䝮䝝䞁䝬䝗䚷䚷䝰䝭䝚䞊䝹

5DKPDQ0G0DPLQXU

䝅䝱䝭䝬䚷䚷䚷䚷䚷䚷䚷䚷䚷䝇䝹䝍䝘

6+$0,0$68/7$1$

࣓ͤࣥࢱ࣮࡟ࡘ࠸࡚
ࠉୖẁ㸸ྡ๓ࠉࠉୗẁ㸸໅ົሙᡤ/,06◊✲ࢸ࣮࣐࣑ࢫ࣐ࢵࢳಟ᚟ᅉᏊ0/+ཬࡧ
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7KHUROHRIPLVPDWFKUHSDLU
005 IDFWRUVWKH0/+DQG
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HOHFWURHQFHSKDORJUDPLQQDWLRQZLGHRUJOREDODUHD

䝍䜿䝎



⸆
⸆
⛉ ⑓ែ᝟ሗ⸆Ꮫ
Ꮫ
Ꮫ

᝟་
⸆ ሗ⸆
ࢩࢫࢸ࣒ࢣࣔࢭࣛࣆ࣮

Ꮫ ⛉๰
Ꮫᡂ

䝬䝒䝰䝖

䜰䜻䝠䝻

ᯇᮏࠉ᫂ᏹ

䝸

䝉䝒 䝠䝵䜴

ᮤࠉࠉ㞷ịࡀࢇศᏊᶆⓗ໬Ꮫ⒪ἲ࡟࠾ࡅࡿ
ప㓟⣲ᛂ⟅ࢩࢢࢼࣝ㸸8&+/
+,)⤒㊰$UHVHDUFKLQPROHFXODUWDUJHWFKHPRWKHUDS\RIFDQFHULQ
K\SR[LDUHVSRQVHVLJQDOV
8&+/+,)3DWKZD\

䝭䜴䝷

䝸䝃䝁

୕ᾆࠉ⌮⣪Ꮚ

ච␿⣔ࢆไᚚࡋ࠼ࡿ᪂つࢼࣀᚤ⢏Ꮚࡢ㛤Ⓨ'HYHORSPHQWRIQHZIXQFWLRQDOQDQRSDUWLFOHVIRULPPXQRWKHUDS\

࣓ࣥࢱ࣮

䝬䝒䝝䝅

䝰䝸䚷䚷䝲䝇䜸

᳃ࠉὈ⏕ࠉᩍᤵ

་Ꮫ◊✲⛉ࠉ㑇ఏ་Ꮫㅮᗙ
ᨺᑕ⥺㑇ఏᏛ

ᕤᏛ◊✲⛉ࠉྜᡂ࣭⏕≀໬Ꮫᑓᨷ⏕≀໬ᏛㅮᗙࠉศᏊ⏕≀໬Ꮫศ㔝䝬䝃䜸ᯇᶫ䚷┾⏕䚷≉ᐃ෸ᩍᤵ་Ꮫ◊✲⛉⬻ᶵ⬟⥲ྜ◊✲ࢭࣥࢱ࣮䝕䜱䞁䚷㻌㻌㻌㻌䝝㻌㻌㻌㻌㻌䝴䜱䚷㻌㻌㻌㻌䝔䜱䝍䜹䝝䝅䚷䚷䝸䝵䜴䝇䜿䜹䜿䝲䚷䚷䚷䝠䝕䜰䜻㧘ᶫࠉⰋ㍜ࠉᩍᤵ

᥃㇂ࠉ⚽᫛ࠉᩍᤵ

'LQK+D'X\7KX\䚷◊✲ဨ་Ꮫ◊✲⛉ࠉ⬻⑓ែ⏕⌮Ꮫㅮᗙ⮫ᗋ⚄⤒Ꮫ⸆Ꮫ◊✲⛉་⸆๰ᡂ᝟ሗ⛉Ꮫᑓᨷ་⸆๰ᡂ᝟ሗ⛉Ꮫㅮᗙ㺚㺛㺡㺯㺗㺱㺜㺵㺩㺽㺎 ไᚚศᏊᏛ

་Ꮫ◊✲⛉⬻ᶵ⬟⥲ྜ◊✲ࢭࣥࢱ࣮

䝶䝅䝜䝤

䝃䜹䜲

䝶䝅䝝䝹

䝍䜹䝝䝅

䝯䜲䝁

㧘಴ࠉ႐ಙࠉᩍᤵ

ᆏ஭ࠉ⩏἞ࠉᩍᤵ

㧗ᶫࠉࡵ࠸Ꮚࠉ≉ᐃㅮᖌ⸆Ꮫ◊✲⛉ࠉ⸆Ꮫᑓᨷ
⑓ែᶵ⬟ゎᯒᏛㅮᗙࠉ⑓ែ᝟ሗ⸆Ꮫศ㔝་Ꮫ◊✲⛉ࠉእ⛉Ꮫㅮᗙᾘ໬⟶እ⛉Ꮫ

་Ꮫ◊✲⛉㝃ᒓࢤࣀ࣒་Ꮫࢭࣥࢱ࣮
⑌ᝈࢤࣀ࣒␿Ꮫゎᯒศ㔝 ᯇ⏣◊✲ᐊ䜹䜿䝲䚷䚷䚷䝠䝕䜰䜻䝇䝈䜻᥃㇂ࠉ⚽᫛ࠉᩍᤵ

㕥ᮌࠉⱱᙪࠉᩍᤵ

኱▼䚷┤ஓ䚷≉ᐃㅮᖌ⸆Ꮫ◊✲⛉་⸆๰ᡂ᝟ሗ⛉Ꮫᑓᨷ་⸆๰ᡂ᝟ሗ⛉Ꮫㅮᗙ㺚㺛㺡㺯㺗㺱㺜㺵㺩㺽㺎 ไᚚศᏊᏛ

་Ꮫ◊✲⛉ࠉឤぬ㐠ື⣔እ⛉Ꮫㅮᗙ
ᙧᡂእ⛉Ꮫ

་Ꮫ◊✲⛉
ࠉ⬻ᶵ⬟⥲ྜ◊✲ࢭࣥࢱ࣮

䜰䜻䝶䝅

㧗
ศ
ᕤ
Ꮚ ⏕యᶵ⬟㧗ศᏊ

Ꮫ
໬
Ꮫ

䝅䝳䞁䜲䝏

Ṋ⏣ࠉಇ୍ࠉᩍᤵ

䝍䜹䜽䝷࢚࢟ࢯࢯ࣮࣒ࢆ฼⏝ࡋࡓ㧗㱋⪅⑌ᝈࡢ἞⒪ἲࡢ㛤Ⓨ'HYHORSPHQWRI([RVRPHEDVHG
WUHDWPHQWIRUHOGHUO\SHRSOH/,06ᣦᑟᩍᤵ

◊✲⛉ᣦᑟᩍᤵ

䜹䝈䝘䝸

䜻䝮䝷

䝅䝀䝠䝁

䝅䝳䞁䝃䜽

䜸䜸䜲䝅

䝍䜹䝝䝅

䝘䜸䝲

䝯䜲䝁

⛅ྜྷࠉ୍ᡂࠉᩍᤵ

ᮌᮧࠉಇసࠉᩍᤵ

㧗ᶫࠉࡵ࠸Ꮚࠉ≉ᐃㅮᖌᕤᏛ◊✲⛉ࠉ㧗ศᏊ໬Ꮫᑓᨷ
㧗ศᏊ≀ᛶㅮᗙ⏕యᶵ⬟㧗ศᏊศ㔝ᕤᏛ◊✲⛉ࠉᮦᩱ໬Ꮫᑓᨷ
㧗ศᏊᮦᩱ໬Ꮫㅮᗙ⏕యᮦᩱ໬Ꮫศ㔝་Ꮫ◊✲⛉㝃ᒓࢤࣀ࣒་Ꮫࢭࣥࢱ࣮
⑌ᝈࢤࣀ࣒␿Ꮫゎᯒศ㔝 ᯇ⏣◊✲ᐊ
࣓ͤࣥࢱ࣮࡟ࡘ࠸࡚
ࠉୖẁ㸸ྡ๓ࠉࠉୗẁ㸸໅ົሙᡤᖹ ᡂ㸰㸷ᖺᗘ㸦㹊㸲㸧ࠉ㹊㹇㹋㹑ᒚಟ⪅࣭ᣦᑟᩍᤵ࣭࣓ࣥࢱ୍࣮ぴ
◊
✲
⛉

ᑓᨷ

་
Ꮫ

་
⛉
Ꮫ

ศ㔝➼

Ặྡ

/,06◊✲ࢸ࣮࣐

䝍䜹䝝䝅















་
Ꮫ

⸆
Ꮫ

་
⛉
Ꮫ

⸆
⛉
Ꮫ

L36⣽⬊◊✲ᡤ⮫ᗋᛂ⏝◊✲㒊㛛⑌ᝈ෌⌧◊✲ศ㔝㑇ఏ་Ꮫㅮᗙ
ᨺᑕ⥺㑇ఏᏛ໬Ꮫ◊✲ᡤ⏕యᶵ⬟໬Ꮫ◊✲⣔⏕యᶵ⬟タィ໬Ꮫ᝟་་⸆๰ᡂ᝟ሗ⛉Ꮫㅮᗙ⸆ ሗ⸆ࢩࢫࢸ࣒ࣂ࢖࢜ࣟࢪ࣮ศ
Ꮫ ⛉๰
㔝
Ꮫᡂ

ᕤ
Ꮫ

ᕤ
Ꮫ

ศ
Ꮚ
ᕤ
Ꮫ

㧗
ศ
Ꮚ
໬
Ꮫ

⏕యศᏊᶵ⬟໬Ꮫㅮᗙ㧗ศᏊྜᡂㅮᗙ
㔜ྜ໬Ꮫศ㔝⏕ྜᕤ ≀ྜᡂ໬ᏛㅮᗙᡂᏛ ໬≀⌮᭷ᶵ໬Ꮫศ㔝࣭Ꮫ䝬䝒䝞䝷

L36⣽⬊⏤᮶1.⣽⬊ࢆ⏝࠸ࡓ⑌ᝈ἞⒪࡟㛵ࡍࡿ◊✲/,06ᣦᑟᩍᤵ

◊✲⛉ᣦᑟᩍᤵ

䝆䝳䞁

䜰䝎䝏

䝍䜲䝆

࣓ࣥࢱ࣮

䝘䜺䝲䝇

䜹䝈䜻

㧘ᶫࠉ῟ࠉᩍᤵ

Ᏻ㐩ࠉὈ἞ࠉᩍᤵ

ỌᏳ䚷୍ᶞ䚷≉ᐃຓᩍ

L36⣽⬊◊✲ᡤ⮫ᗋᛂ⏝◊✲㒊㛛⚄⤒෌⏕◊✲ศ㔝෌⏕་⛉Ꮫ◊✲ᡤࢼࣀ෌⏕་ᕤᏛ◊✲ࢭࣥࢱ࣮ࣂ࢖࣓࢜࢝ࢽࢡࢫ◊✲㡿ᇦ⸆Ꮫ◊✲⛉ࠉ⏕యᶵ⬟ゎᯒᏛศ㔝㸦㔠Ꮚ◊✲ᐊ㸧

䝠䝻䝴䜻

ᯇཎࠉᘯᖾ

㸦1.FHOOVGHULYHGIURPL36FHOOVIRUD
FOLQLFDODSSOLFDWLRQ㸧䝍䜿䝎䚷䚷䚷䚷䚷䚷㻌㻌㻌䝅䝳䞁䜲䝏䝬䜶䜹䝽Ṋ⏣ࠉಇ୍ࠉᩍᤵ

๓ᕝࠉᖹࠉᩍᤵ

ᯇᶫ䚷┾⏕䚷≉ᐃ෸ᩍᤵ་Ꮫ◊✲⛉ࠉ㑇ఏ་Ꮫㅮᗙ
ᨺᑕ⥺㑇ఏᏛ

་Ꮫ◊✲⛉ࠉ㍺⾑་Ꮫ་Ꮫ◊✲⛉⬻ᶵ⬟⥲ྜ◊✲ࢭࣥࢱ࣮䝍䜲䝷

$VVHVVPHQWRIWKHSURWHRO\WLFDFWLYLW\䝃䝝䚷䚷䚷䚷䚷䚷䚷䚷䚷䝸䝖䞁䚷䚷䚷䚷䚷䜽䝬䞊䝹
6$+$/LWRQ.XPDU UROHRI63571LQ'1$3URWHLQFURVVOLQNUHSDLULQKXPDQ

᪂つ51$ไᚚᶵ⬟䝍䞁䝟䜽㉁䛻䜘䜛⪁໬䞉⑌ᝈไᚚ䛾᳨ウ

䝬䝒䝝䝅

䝬䝃䜸

䝣䝍䜻䚷䚷䚷䚷䚷䚷䚷䚷䝅䝻䜴䝬䝒䝎஧ᮌࠉྐᮁࠉᩍᤵ

ᯇ⏣ࠉ㐨⾜ࠉᩍᤵ

⸨ᮏ䚷᫭ྖ䚷≉ᐃຓᩍ໬Ꮫ◊✲ᡤࠉ⏕యᶵ⬟໬Ꮫ◊✲⣔⏕యᶵ⬟タィ໬Ꮫ་Ꮫ◊✲⛉ࠉᇶ♏⑓ែᏛㅮᗙ
⑓ែ⏕≀་Ꮫ

་Ꮫ◊✲⛉⬻ᶵ⬟⥲ྜ◊✲ࢭࣥࢱ࣮

䝭䝏䝴䜻

䝣䝆䝰䝖

䝁䜴䝆

䝅䝜䝎䚷䚷䚷䚷䚷䚷䚷䝁䜴䜻⠛⏣ࠉ᪸ᶞ䝗䜴䝆䝵䜴䚷䚷䚷䚷䚷䚷䜽䝭䝁ᇽୖࠉஂ⨾Ꮚ

&RQWURORIDJLQJDQGGLVHDVHVXVLQJIXQFWLRQDOSURWHLQVUHJXODWLQJVSHFLILF
51$

ࢩࣇࢺ࣮࣮࣡࢝ࡀ࠿࠿ࡾࡸࡍ࠸⑓Ẽࡢ◊✲
㸦7KH+HDOWK5LVNVRI6KLIW:RUN㸧䜴䝜䚷䚷䚷䚷䚷䚷䚷䚷䝬䝃䝖䝅Ᏹ㔝ࠉ㞞ಇ

ᢠ⅖⑕ࢩࢢࢼࣝࢱࣥࣃࢡ㉁7,$53ࡢ
ᶵ⬟ゎᯒ㸦)XQFWLRQDODQDO\VLVRI7,$53DV
DQWLLQIODPPDWRU\VLJQDOSURWHLQ㸧⏕యศᏊᐃ㔞ࡢࡓࡵࡢ᭷ᶵ㸫↓ᶵࣁ࢖ࣈࣜࢵࢻᮦᩱࢆᇶ┙࡜ࡋࡓᶵ⬟ᛶගᏛᮦᩱࡢ㛤Ⓨ䜸䜹䝮䝷䚷䚷䚷䚷䚷䚷䝠䝖䝅䝽䝍䝘䝧䚷䚷䚷䚷䝎䜲ᒸᮧࠉᆒࠉᩍᤵ

Ώ㑓ࠉ኱ࠉᩍᤵ

䜻䝮䝷ᮌᮧ䚷♸䚷≉ᐃ෸ᩍᤵ

䝴䜴

⸆Ꮫ◊✲⛉
་⸆๰ᡂ᝟ሗ⛉Ꮫᑓᨷ་⸆๰ᡂ᝟ሗ⛉Ꮫㅮᗙࢩࢫࢸ࣒ࣂ࢖࢜ࣟࢪ࣮ศ㔝་Ꮫ◊✲⛉ࠉ⏕య᝟ሗ⛉Ꮫㅮᗙ⏕య᝟ሗ⛉Ꮫ

ᕤᏛ◊✲⛉䚷≀㉁䜶䝛䝹䜼䞊໬Ꮫᑓᨷඛ➃་ᕤᏛศ㔝䝅䝷䜹䝽䚷䚷䚷䚷䚷䚷䚷䝬䝃䝠䝻䜲䝽䝍䚷䚷䚷䚷䚷䚷䚷䚷䝋䜴䚷ⓑᕝࠉᫀᏹࠉᩍᤵ

ᒾ⏣ࠉ᝿ࠉᩍᤵ

㧗ᶫࠉࡵ࠸Ꮚࠉ≉ᐃㅮᖌᕤᏛ◊✲⛉ࠉศᏊᕤᏛᑓᨷ
⏕యศᏊᶵ⬟໬Ꮫㅮᗙ་Ꮫ◊✲⛉ࠉศᏊ⏕య⤫ᚚᏛㅮᗙศᏊ⣽⬊᝟ሗᏛ

་Ꮫ◊✲⛉㝃ᒓࢤࣀ࣒་Ꮫࢭࣥࢱ࣮
⑌ᝈࢤࣀ࣒␿Ꮫゎᯒศ㔝㸦ᯇ⏣◊✲ᐊ㸧䝏䝳䜴䝆䝵䜴䚷䚷䚷䚷䝶䝅䜻

䜰䝎䝏

䝋䜴䜲䝏

䝍䜹䝝䝅

䝯䜲䝁

ࣄ࢞ࢩࣔࣜ

ࣀࣈࣘ࢟

୰ᲄࠉၿᶞࠉᩍᤵ

㊊❧ኋ୍ࠉᩍᤵ

ᮾ᳃ࠉಙᑵࠉ≉ᐃㅮᖌᕤᏛ◊✲⛉ࠉ㧗ศᏊ໬Ꮫᑓᨷ
㧗ศᏊྜᡂㅮᗙࠉ㔜ྜ໬Ꮫศ㔝་Ꮫ◊✲⛉ࠉே㛫೺ᗣ⛉Ꮫ⣔ᑓᨷ᳨ᰝᢏ⾡⛉Ꮫࢥ࣮ࢫ
་⒪᳨ᰝᒎ㛤Ꮫㅮᗙ᳨ᰝᛂ⏝㛤ⓎᏛ᝟ሗᏛ◊✲⛉
ᛂ⏝ゎᯒᏛㅮᗙ
㸦☾◊✲ᐊ㸧

䝇䜶䝘䜺䚷䚷䚷䚷䚷䚷䜹䝈䝬䝃ᮎỌࠉ࿴┿

㸦'HYHORSPHQWRI)XQFWLRQDO2SWLFDO
0DWHULDOVIRU4XDQWLI\LQJ%LRPROHFXOHV%DVHGRQ2UJDQLF,QRUJDQLF+\EULGV㸧⏕య㉸ศᏊࡢᵓ⠏ࢆ┠ᣦࡋࡓ༠ྠⓗ⤌⧊໬ࣉࣟࢭࢫࡢไᚚ

䝬䝒䝎䚷䚷䚷䚷䚷䚷䚷䚷䜿䞁䝆䝜䝎䚷䚷䚷䚷䚷䚷䚷䚷䚷䝬䝁䝖ᯇ⏣ࠉᘓඣࠉᩍᤵ

㔝⏣ࠉுࠉᩍᤵ

ᕤᏛ◊✲⛉ࠉྜᡂ࣭⏕≀໬Ꮫᑓᨷྜᡂ໬Ꮫㅮᗙࠉ≀⌮᭷ᶵ໬Ꮫศ㔝་Ꮫ◊✲⛉ࠉศᏊ⏕య⤫ᚚᏛㅮᗙ
ศᏊ⭘⒆Ꮫ

䝘䜺䝲䝇

䜹䝈䜻

ỌᏳࠉ୍ᶞࠉ≉ᐃຓᩍ䝙䝅䝍䝙䚷䚷䚷䚷䚷䝜䝤䝠䝁す㇂ࠉᬸᙪ

㸦&RQWURORI&RRSHUDWLYH6HOI
$VVHPEO\IRU%LR,QVSLUHG
6XSUDPROHFXODU0DWHULDOV㸧⸆Ꮫ◊✲⛉ࠉ⏕యᶵ⬟ゎᯒᏛศ㔝㸦㔠Ꮚ◊✲ᐊ㸧ᖹ ᡂ㸰㸷ᖺᗘ㸦㹊㸳㸧ࠉ/,06ᒚᒚ ಟ⪅࣭ᣦᑟᩍᤵ࣭࣓ࣥࢱ୍࣮ぴ
◊
✲
⛉

ᑓ
ᨷ

ศ㔝➼

/,06◊✲ࢸ࣮࣐Ặྡ࣓ͤࣥࢱ࣮࡟ࡘ࠸࡚
ࠉୖẁ㸸ྡ๓ࠉࠉୗẁ㸸໅ົሙᡤ◊✲⛉ᣦᑟᩍᤵ䜹䝛䝁⸆⑓ែᶵ⬟ゎᯒᏛㅮᗙ
⸆⛉⏕యᶵ⬟ゎᯒᏛᏛᏛ⏕ྜᕤ ≀ ⏕≀໬ᏛㅮᗙᡂᏛ ໬ ⏕యㄆ㆑໬Ꮫศ㔝࣭Ꮫ⪁໬࣐࢘ࢫ࡟࠾ࡅࡿㄆ▱ᶵ⬟㞀ᐖࡢ
ཎᅉゎ᫂
䝭䝲䝜䝝䝷

䜻䝜䝅䝍

䜰䝲 䜶

࣓ࣥࢱ࣮

䜻䝮䝷

䝴䜴

㔠Ꮚࠉ࿘ྖࠉᩍᤵ

ᮌୗࠉᙬᰤࠉᩍᤵ

ᮌᮧ䚷♸䚷≉ᐃ෸ᩍᤵ⸆Ꮫ◊✲⛉ࠉ⸆Ꮫᑓᨷ
⑓ែᶵ⬟ゎᯒᏛㅮᗙࠉ⏕యᶵ⬟ゎᯒᏛศ㔝་Ꮫ◊✲⛉ࠉᆅᇦ┳ㆤᏛᅾᏯ་⒪┳ㆤᏛ

ᕤᏛ◊✲⛉䚷≀㉁䜶䝛䝹䜼䞊໬Ꮫᑓᨷඛ➃་ᕤᏛศ㔝

䝆䝳䞁

ᐑஅཎࠉ㑂

0ROHFXODUPHFKDQLVPRIFRJQLWLYH
LPSDLUPHQWLQDJHGPLFH

ຍ㱋࡟క࠺೺ᗣ㞀ᐖ࡜⭠ෆ⣽⳦࡜ࡢ㛵ࢃࡾ࡟ࡘ࠸࡚
䝇䜲䝖䜴䝅䝳䜴䝆/,06ᣦᑟᩍᤵ

䜴䝯䝎䚷䚷䚷䚷䚷䚷䚷䚷䝬䝃䝖䝽䝍䝘䝧䚷䚷䚷䚷䝎䜲䝠䜺䝅䝰䝸ᱵ⏣ࠉ┿㒓ࠉᩍᤵ

Ώ㑓ࠉ኱ࠉᩍᤵ

ᮾ᳃ࠉಙᑵࠉ≉ᐃㅮᖌᕤᏛ◊✲⛉ࠉྜᡂ࣭⏕≀໬Ꮫᑓᨷ⏕≀໬Ꮫㅮᗙࠉ⏕యㄆ㆑໬Ꮫศ㔝་Ꮫ◊✲⛉ࠉ⏕య᝟ሗ⛉Ꮫㅮᗙ⏕య᝟ሗ⛉Ꮫ

᝟ሗᏛ◊✲⛉
ᛂ⏝ゎᯒᏛㅮᗙ
㸦☾◊✲ᐊ㸧

䝜䝤䝴䜻

䝍䜽 䝖

Ỉ⸨ࠉᣅே

㸦6WXG\RQDJHUHODWHGGLVHDVHDQG
JXWPLFURELRPH㸧

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‫گ‬үΩϨΫϣϧϞ‫ࢨ;ٶ‬಍ର੏&XUULFXOXP DQG VWDII⛉┠⩌⛉䚷䚷䚷┠ᢸᙜ⪅㻺㼛㼚㻌㼙㼑㼐㼕㼏㼍㼘㻺㼛㻹㼑㼐㼕㼏㼍㼘

㻌ᖹᡂ㻞㻥ᖺᗘ䚷ᒚಟ⛉┠⾲㻌䠄་Ꮫᑓᨷ㻌༤ኈㄢ⛬䠅
༤ኈㄢ⛬
䠍ᖺḟ

㻞ᖺḟ

㻟ᖺḟ

㻠ᖺḟ

๓

ᚋ

๓

๓

๓

㻞

㻞

㻝

ᶵᲔᕤᏛᇶ♏

୰㒊䞉Ᏻ㐩㻞་⏝㟁ᏊᕤᏛ

᳝ྡ䞉ᮡᮏ㻟ᮦᩱ໬Ꮫᇶ♏

㏆⸨䞉ᮌᮧ♸㻠ᕤᏛ ་⸆⏝㧗ศᏊタィᏛ

⏣⏿

㻡

㐃⥆యຊᏛ

Ᏻ㐩

㻞

㻢

⏕≀ศᏊゎᯒᏛ᳃䞉す㻞㻣⏬ീฎ⌮䛾ᇶ♏

ᮡᮏ㻖㻝㑅ᢥᚲಟᚋᚋഛ⪃ᚋ๓ᮇ㻘ᚋᮇ䛹䛱䜙䛷䜒ྍ㻞㻖㻝㑅ᢥᚲಟ㻞㻞㻞㻤 ᇶ┙ ⸆Ꮫ ⸆≀ືែᏛ୰ᒣ䞉㧗಴䞉ᒣୗ䞉ᵽཱྀ㻥ⴗཎ䞉ᒣ⏣䞉Ḉ஭ච㝖 ᚲಟఀబ䞉㻌㻯㻴㻭㻻

ච㝖 ᚲಟ

㻞

⛉┠

ேయゎ๗Ꮫ

㻝㻜

ㅮ⩏㻝⛉┠㻟㻜ᖺ
ᗘ䛻㛤ㅮ

㻡

㻝㻞

⏕⌮Ꮫ
་Ꮫ䞉
⏕≀ ་໬Ꮫ
Ꮫ
ຍ㱋་Ꮫ

㻝㻟

෌⏕་Ꮫ

℩ཎ䞉⏣⏿䞉Ᏻ㐩䝀䝜䝮䝁䝩䞊䝖◊✲ᯇ⏣ᩥ䞉㧗ᶫ

㻞

⚟ᒣ䞉ᑠᮡ

㻝

㻝㻝

㻝㻠
㻝㻡

་⒪೔
་⒪೔⌮
⌮

㻝㻢

ᇶ♏ᩘᏛ

Ώ㑓䞉㼅㻻㼁㻿㻿㻱㻲㻵㻭㻺

㻝㻥
㻞㻜

་⒪
⤒῭Ꮫ

ᮾ᳃

㻞㻞

㻞
㻞

ᚲಟ

㻞
㻞

㻖㻞
㑅ᢥ
ᚲಟ

௒ᖺᗘ㛤ㅮ䛫䛪

ᛂ⏝ᩘᏛ

ᮾ᳃

་⒪⤒῭ㄽ

ᚋ⸨

ᚲಟ

㻞

▱ⓗ㈈⏘䠃ᅜ㝿ᶆ‽໬

⚟ᒣ䞉ᑎす

ᚲಟ

㻞

㻞㻝 ་⒪ᕤᏛ≉ ་⒪ᕤᏛ≉ูㅮ⩏䊠
ูㅮ⩏

㻞

⚟ᒣ䚸Ⲩ஭

㻝㻣 ᩘ⌮⛉Ꮫ 䝅䝭䝳䝺䞊䝅䝵䞁ᴫㄽ㻝㻤㻞་⒪ᕤᏛ≉ูㅮ⩏䊡

㻞

⚟ᒣ

㻞

⚟ᒣ

䠕᭶䡚
㻞

㻝㻚⏬ീデ᩿Ꮫ

㻞㻟䚷㻝㻙㻝㻌㻌⑓⌮⏬ീデ᩿Ꮫ⩚㈡

㻞㻠䚷㻝㻙㻞㻌㻌ᨺᑕ⥺⏬ീデ᩿Ꮫ⚟ᒣ㻞㻡䚷㻝㻙㻟䚷㻹㻾㻵⏬ീデ᩿Ꮫ

⚟ᒣ

㻝
Ꮫ㝿

㻞㻢 ᛂ⏝ ㅮ⩏ 㻞㻚ప౵く἞⒪Ꮫ
㻞㻣

㻝

⛉┠

ᮌᮧ๛䞉㧗ᢡ

㻝㻟㻚⏕యᮦᩱᏛ䞉ேᕤ⮚ჾᏛ⏣⏿䞉ᯇ⏣⚽㻝㻞㻤㻠㻚་⒪᝟ሗᏛ㯮⏣㻝㻞㻥㻡㻚᳨ᰝᶵჾᏛ䞉◊✲ᶵჾᏛ

୍ᒣ

㻝

㻟㻜

㻢㻚་⒪䞉⏕άᨭ᥼䝅䝇䝔䝮Ꮫ

᳝ྡ

ᚲಟ

㻝

䠕᭶䡚

ᢸᙜ⪅

㻺㼛㼚㻌㼙㼑㼐㼕㼏㼍㼘⛉䚷䚷䚷䚷┠

㻹㼑㼐㼕㼏㼍㼘

⛉┠⩌

༤ኈㄢ⛬
䠍ᖺḟ

㻞ᖺḟ

㻟ᖺḟ

㻠ᖺḟ

๓

๓

๓

๓

ഛ⪃
ᚋ

ᚋ

ᚋ

ᚋ

㻝㻚⏬ീデ᩿Ꮫ

㻞㻟䚷㻝㻙㻝㻌㻌⑓⌮⏬ീデ᩿Ꮫ⩚㈡

㻞㻠䚷㻝㻙㻞㻌㻌ᨺᑕ⥺⏬ീデ᩿Ꮫ⚟ᒣᐇ⩦ 䚷㻝㻙㻟䚷㻹㻾㻵⏬ീデ᩿ᏛᏛ㝿 ཬ䜃㻞㻢 ᛂ⏝ ⑓㝔 㻞㻚ప౵く἞⒪Ꮫ⛉┠ ෆ◊㻞㻣ಟ 㻟㻚⏕యᮦᩱᏛ䞉ேᕤ⮚ჾᏛ⚟ᒣ⏣⏿䞉ᯇ⏣⚽㻝㻞㻤㻠㻚་⒪᝟ሗᏛ䠖ᐇ⩦

㯮⏣

㻝

㻞㻥

㻡㻚᳨ᰝᶵჾᏛ䞉◊✲ᶵჾᏛ

୍ᒣ

㻝

㻟㻜

㻢㻚་⒪䞉⏕άᨭ᥼䝅䝇䝔䝮Ꮫ

᳝ྡ

ᚲಟ

㻟㻟

ⱥㄒ㻌㼐䡁䠾䠽䡐䡁䊡㻭㼘㼠㼙㼍㼚㼚

ᚲಟ㻟㻠ⱥㄒ㻌㼐䡁䠾䠽䡐䡁䊢㻭㼘㼠㼙㼍㼚㼚

ᚲಟ㻟㻡ⱥㄒ㻌㼐䡁䠾䠽䡐䡁䊣㻭㼘㼠㼙㼍㼚㼚

ᚲಟ㻟㻢ⱥㄒ㻌㼐䡁䠾䠽䡐䡁䊤㻭㼘㼠㼙㼍㼚㼚ᚲಟ㻝㻞㻡ᮌᮧ๛䞉㧗ᢡṊ⏣䞉⚟ᒣ㻟㻣 䜲䞁䝍䞊䞁 ▷ᮇᾏእ䜲䞁䝍䞊䞁䝅䝑䝥䝅䝑䝥௻ᴗ䞉බⓗᶵ㛵䜲䞁䝍䞊䞁䝅䝑䝥 ⚟ᒣ
㻟㻤

㻠㻜

㻝

≉ู◊✲

ᢸᙜᩍဨ

㻝

㻝

㻖㻟㻌㑅ᢥ
ᚲಟ
ᚲಟ

⥙᥃䛡䛿䚸ᒚಟᏛᖺ䞉Ꮫᮇ䚹ᩘᏐ䛿༢఩ᩘ㻖㻝㻌ᶵᲔᕤᏛᇶ♏ཬ䜃ᮦᩱ໬Ꮫᇶ♏䛛䜙ᚲ䛪䠍⛉┠䜢㑅ᢥ䛧ᒚಟ䛩䜛䛣䛸䚹㻖㻞㻌䝅䝭䝳䝺䞊䝅䝵䞁ᴫㄽཬ䜃ᛂ⏝ᩘᏛ䛛䜙ᚲ䛪䠍⛉┠䜢㑅ᢥ䛧ᒚಟ䛩䜛䛣䛸䚹㻖㻟㻌▷ᮇᾏእ䜲䞁䝍䞊䞁䝅䝑䝥ཬ䜃௻ᴗ䞉බⓗᶵ㛵䜲䞁䝍䞊䞁䝅䝑䝥䛛䜙ᚲ䛪䠍⛉┠䜢㑅ᢥ䛧䚸ᒚಟ䛩䜛䛣䛸Ꮫ㝿ᛂ⏝⛉┠䛿䚸ㅮ⩏ཬ䜃ᐇ⩦䛾୧᪉䜢ཷㅮ䛧䛺䛔䛸༢఩䛿ㄆ䜑䜙䜜䛺䛔䚹␃Ꮫ⏕ྥ䛡⛉┠

䠕᭶䡚㻌ᖹᡂ㻞㻥ᖺᗘ䚷ᒚಟ⛉┠⾲㻌㻔⸆Ꮫᑓᨷ㻌༤ኈㄢ⛬䠅
༤ኈㄢ⛬
㻺㼛㻚

⛉┠⩌

⛉䚷䚷䚷┠

ᢸᙜ⪅

㻝

ᶵᲔᕤᏛᇶ♏

୰㒊䞉Ᏻ㐩㻞་⏝㟁ᏊᕤᏛ

᳝ྡ䞉ᮡᮏ㻟ᮦᩱ໬Ꮫᇶ♏

㏆⸨䞉ᮌᮧ♸㻠ᕤᏛ ་⸆⏝㧗ศᏊタィᏛ

༊ศ

㻖㻝

㑅ᢥᚲಟ

䠍ᖺḟ

㻞ᖺḟ

㻟ᖺḟ

㻠ᖺḟ

๓

ᚋ

๓

๓

๓

㻞

㻞

㻖㻝

๓ᮇ㻘ᚋᮇ䛹䛱䜙
䛷䜒ྍ

⏣⏿

㻞

Ᏻ㐩

㻞

㻢

⏕≀ศᏊゎᯒᏛ᳃䞉す㻞㻣⏬ീฎ⌮䛾ᇶ♏

ᮡᮏ㻞㻤 ᇶ┙ ⸆Ꮫ ⸆≀ືែᏛ⛉┠୰ᒣ䞉㧗಴䞉ᒣୗ䞉ᵽཱྀ㻥ⴗཎ䞉ᒣ⏣䞉Ḉ஭ᚲಟఀబ䞉㻌㻯㻴㻭㻻ᚲಟ㻞ᚲಟ䚸ㅮ⩏㻝⛉┠㻟㻜ᖺᗘ䛻㛤ㅮ

㻡

㻝㻞

⏕⌮Ꮫ
་
Ꮫ䞉 ་໬Ꮫ⏕≀Ꮫ ຍ㱋་Ꮫ㻝㻟෌⏕་Ꮫ℩ཎ䞉⏣⏿䞉Ᏻ㐩䝀䝜䝮䝁䝩䞊䝖◊✲ᯇ⏣ᩥ䞉㧗ᶫ

㻞

་⒪೔⌮

⚟ᒣ䞉ᑠᮡ

㻝

ᇶ♏ᩘᏛ

ᮾ᳃

㻝㻝

㻝㻠
་⒪
೔⌮

㻝㻡
㻝㻢

Ώ㑓䞉㼅㻻㼁㻿㻿㻱㻲㻵㻭㻺

㻞
㻞

⚟ᒣ䞉Ⲩ஭

㻞
㻞

㻞

㻝㻣 ᩘ⌮⛉Ꮫ 䝅䝭䝳䝺䞊䝅䝵䞁ᴫㄽ
㻝㻤
㻝㻥
㻞㻜

་⒪
⤒῭Ꮫ

㻞

௒ᖺᗘ㛤ㅮ䛫䛪

ᛂ⏝ᩘᏛ

ᮾ᳃

་⒪⤒῭ㄽ

ᚋ⸨

ᚲಟ

㻞

▱ⓗ㈈⏘䠃ᅜ㝿ᶆ‽໬

⚟ᒣ䞉ᑎす

ᚲಟ

㻞

㻞㻝 ་⒪ᕤᏛ ་⒪ᕤᏛ≉ูㅮ⩏䊠㻞㻞 ≉ูㅮ⩏ ་⒪ᕤᏛ≉ูㅮ⩏䊡

ഛ⪃

ᚋ

㻞

㑅ᢥᚲಟ

㐃⥆యຊᏛ

㻝㻜

ᚋ

㻞

㻡

ேయゎ๗Ꮫ

ᚋ

㻞

⚟ᒣ

㻞

⚟ᒣ

䠕᭶䡚
㻞

㻝㻚⏬ീデ᩿Ꮫ

㻞㻟䚷㻝㻙㻝㻌㻌⑓⌮⏬ീデ᩿Ꮫ⩚㈡

㻞㻠䚷㻝㻙㻞㻌㻌ᨺᑕ⥺⏬ീデ᩿Ꮫ

⚟ᒣ

㻞㻡 Ꮫ㝿

䚷㻝㻙㻟䚷㻹㻾㻵⏬ീデ᩿Ꮫ

⚟ᒣ

ᛂ⏝

㻝
㻝

㻞㻢 ⛉┠ ㅮ⩏ 㻞㻚ప౵く἞⒪Ꮫ

ᮌᮧ๛䞉㧗ᢡ

㻞㻣㻟㻚⏕యᮦᩱᏛ䞉ேᕤ⮚ჾᏛ⏣⏿䞉ᯇ⏣⚽㻝㻞㻤㻠㻚་⒪᝟ሗᏛ㯮⏣㻝㻞㻥㻡㻚᳨ᰝᶵჾᏛ䞉◊✲ᶵჾᏛ

୍ᒣ

㻝

㻟㻜

㻢㻚་⒪䞉⏕άᨭ᥼䝅䝇䝔䝮Ꮫ ᳝ྡ

㻝

ᚲಟ

㻝

䠕᭶䡚

༤ኈㄢ⛬
⛉┠⩌

⛉䚷䚷䚷┠

ᢸᙜ⪅

༊ศ

䠍ᖺḟ

㻞ᖺḟ

㻟ᖺḟ

㻠ᖺḟ

๓

๓

๓

๓

ഛ⪃
ᚋ

ᚋ

ᚋ

ᚋ

㻝㻚⏬ീデ᩿Ꮫ

㻞㻟䚷㻝㻙㻝㻌㻌⑓⌮⏬ീデ᩿Ꮫ⩚㈡

㻞㻠䚷㻝㻙㻞㻌㻌ᨺᑕ⥺⏬ീデ᩿Ꮫ⚟ᒣ㻞㻡 Ꮫ㝿 ᐇ⩦ 䚷㻝㻙㻟䚷㻹㻾㻵⏬ീデ᩿Ꮫ
ᛂ⏝

ཬ䜃

㻝
㻝

⚟ᒣ

㻞㻢 ⛉┠ ⑓㝔 㻞㻚ప౵く἞⒪Ꮫ

ᮌᮧ๛䞉㧗ᢡ㻞㻣ෆ◊ಟ 㻟㻚⏕యᮦᩱᏛ䞉ேᕤ⮚ჾᏛ⏣⏿䞉ᯇ⏣⚽㻝㻞㻤㻠㻚་⒪᝟ሗᏛ䠖ᐇ⩦

㯮⏣

㻝

㻞㻥

㻡㻚᳨ᰝᶵჾᏛ䞉◊✲ᶵჾᏛ

୍ᒣ

㻝

㻟㻜

㻢㻚་⒪䞉⏕άᨭ᥼䝅䝇䝔䝮Ꮫ ᳝ྡ㻝ᚲಟ㻟㻝 䚷䚷䚷ศ㔝ᶓ᩿ᆺ኱Ꮫ㝔ᩍ⫱䝁䞊䝇་Ꮫ◊✲⛉ᩍဨ

㻟㻟ⱥㄒ㻌㼐䡁䠾䠽䡐䡁䊡㻭㼘㼠㼙㼍㼚㼚

ᚲಟ㻟㻠ⱥㄒ㻌㼐䡁䠾䠽䡐䡁䊢㻭㼘㼠㼙㼍㼚㼚

ᚲಟ㻟㻡ⱥㄒ㻌㼐䡁䠾䠽䡐䡁䊣㻭㼘㼠㼙㼍㼚㼚

ᚲಟ㻟㻢ⱥㄒ㻌㼐䡁䠾䠽䡐䡁䊤㻭㼘㼠㼙㼍㼚㼚

ᚲಟ

Ṋ⏣䞉⚟ᒣ

㻖㻞㻌㑅ᢥ
ᚲಟ

㻟㻣 䜲䞁䝍䞊䞁 ▷ᮇᾏእ䜲䞁䝍䞊䞁䝅䝑䝥
㻟㻤
㻠㻜

䝅䝑䝥

௻ᴗ䞉බⓗᶵ㛵䜲䞁䝍䞊䞁䝅䝑⚟ᒣ
≉ู◊✲

ᢸᙜᩍဨ

㻝

ᚲಟ

⥙᥃䛡䛿䚸ᒚಟᏛᖺ䞉Ꮫᮇ䚹ᩘᏐ䛿༢఩ᩘ㻖㻝㻌ᶵᲔᕤᏛᇶ♏ཬ䜃ᮦᩱ໬Ꮫᇶ♏䛛䜙ᚲ䛪䠍⛉┠䜢㑅ᢥ䛧ᒚಟ䛩䜛䛣䛸䚹㻖㻞㻌▷ᮇᾏእ䜲䞁䝍䞊䞁䝅䝑䝥ཬ䜃௻ᴗ䞉බⓗᶵ㛵䜲䞁䝍䞊䞁䝅䝑䝥䛛䜙ᚲ䛪䠍⛉┠䜢㑅ᢥ䛧䚸ᒚಟ䛩䜛䛣䛸Ꮫ㝿ᛂ⏝⛉┠䛿䚸ㅮ⩏ཬ䜃ᐇ⩦䛾୧᪉䜢ཷㅮ䛧䛺䛔䛸༢఩䛿ㄆ䜑䜙䜜䛺䛔䚹␃Ꮫ⏕ྥ䛡⛉┠

䠕᭶䡚ᖹᡂ䠎䠕ᖺᗘ㻌ᒚಟ⛉┠⾲䠄༤ኈᚋᮇㄢ⛬⦅ධ⏕䠅
㻺㼛

⛉㻌㻌㻌┠

⛉┠⩌

༤ኈᚋᮇ

㛤ㅮᮇ

ᢸᙜ⪅

๓ ᚋ
㻞

䚷ᶵᲔᕤᏛᇶ♏㻌㻞䚷་⏝㟁ᏊᕤᏛ㻌㻞 ᳝ྡ䞉ᮡᮏ

㻟䚷ᮦᩱ໬Ꮫᇶ♏䚷㻞 ㏆⸨䞉ᮌᮧ♸㻠ᕤᏛ 䚷་⸆⏝㧗ศᏊタィᏛ㻌㻞 ⏣⏿䚷㐃⥆యຊᏛ㻌㻞 Ᏻ㐩㻢䚷⏕≀ศᏊゎᯒᏛ㻌

㻞 ᳃䞉す

㻣

䠆⏬ീฎ⌮䛾ᇶ♏㻌㻞㻤 ᇶ┙ ⸆Ꮫ 䠆⸆≀ືែᏛ㻌
⛉┠

㻝㻜

䚷⏕⌮Ꮫ㻌

㻝㻝

་Ꮫ䞉
⏕≀ 䠆་໬Ꮫ㻌Ꮫ䠆ຍ㱋་Ꮫ㻌

㻝㻞

㻝㻠
་⒪
೔⌮

㻝㻡
㻝㻢

㻡

㻞

Ώ㑓䞉㼅㻻㼁㻿㻿㻱㻲㻵㻭㻺

㻞

⚟ᒣ䚸Ⲩ஭
㻞 ℩ཎ䞉⏣⏿䞉Ᏻ㐩䚷䝀䝜䝮䝁䝩䞊䝖◊✲㻞ᯇ⏣ᩥ䞉㧗ᶫ

䠆་⒪೔⌮

㻝

⚟ᒣ䞉ᑠᮡ

䠆ᇶ♏ᩘᏛ

㻞

ᮾ᳃
㻞

䠆ᛂ⏝ᩘᏛ

㻝㻥
་⒪⤒῭Ꮫ
㻞㻜

ูㅮ⩏

௒ᖺᗘ㛤ㅮ䛫䛪㻞 ᮾ᳃䠆་⒪⤒῭ㄽ㻌㻞ᚋ⸨䠆▱ⓗ㈈⏘䠃ᅜ㝿ᶆ‽໬㻌

㻞

⚟ᒣ䞉ᑎす

㻞㻝 ་⒪ᕤᏛ≉ 䠆་⒪ᕤᏛ≉ูㅮ⩏䊠㻞㻞䠆་⒪ᕤᏛ≉ูㅮ⩏䊡㻌ㅮ⩏㻝⛉┠㻟㻜ᖺᗘ䛻㛤ㅮⴗཎ䞉ᒣ⏣䞉Ḉ஭㻞 ఀబ䞉㻌㻯㻴㻭㻻㻝㻣 ᩘ⌮⛉Ꮫ 䠆䝅䝭䝳䝺䞊䝅䝵䞁ᴫㄽ㻌㻝㻤ᮡᮏ㻞 ୰ᒣ䞉㧗಴䞉ᒣୗ䞉ᵽཱྀ

䚷෌⏕་Ꮫ

㻝㻟

๓ᮇ䚸ᚋᮇ䛹䛱䜙䛷䜒ྍ㻞 ୰㒊䞉Ᏻ㐩㻡䚷ேయゎ๗Ꮫ㻌ഛ⪃๓ ᚋ ๓ ᚋ ๓ ᚋ㻝㻥䠏ᖺḟ 䠐ᖺḟ 䠑ᖺḟ

㻞 ⚟ᒣ
㻞

䠕᭶䡚

⚟ᒣ

䠆䚷㻝㻚㻌⏬ീデ᩿Ꮫ㻌㻞㻟䚷䚷㻌㻌㻝㻙㻝㻌⑓⌮⏬ീデ᩿Ꮫ㻞㻠䚷䚷䚷㻝㻙㻞㻌ᨺᑕ⥺⏬ീデ᩿Ꮫ

㻞㻡 Ꮫ
㝿
㻞㻢 ᛂ
⏝
㻞㻣 ⛉
┠
㻞㻤

䚷䚷䚷㻝㻙㻟㻌䠩䠮䠥⏬ീデ᩿Ꮫ
ㅮ
⩏

㻝 ⩚㈡
㻝

⚟ᒣ
⚟ᒣ

䠆䚷㻞㻚㻌ప౵く἞⒪Ꮫ㻌㻝 ᮌᮧ๛䞉㧗ᢡ䠆䚷㻟㻚㻌⏕యᮦᩱᏛ䞉ேᕤ⮚ჾᏛ㻌㻝 ⏣⏿䞉ᯇ⏣⚽䠆䚷㻠㻚㻌་⒪᝟ሗᏛ

㻝 㯮⏣

㻞㻥

䠆䚷㻡㻚㻌᳨ᰝᶵჾᏛ䞉◊✲ᶵჾᏛ㻌

㻝 ୍ᒣ

㻟㻜

䠆䚷㻢㻚㻌་⒪䞉⏕άᨭ᥼䝅䝇䝔䝮Ꮫ 㻝

᳝ྡ

㻝

ᚲಟ
䠕᭶䡚

㻺㼛

⛉㻌㻌㻌┠

⛉┠⩌

༤ኈᚋᮇ

㛤ㅮᮇ

ᢸᙜ⪅

๓ ᚋ

ഛ⪃

䠏ᖺḟ 䠐ᖺḟ 䠑ᖺḟ๓ ᚋ ๓ ᚋ ๓ ᚋ䠆䚷㻝㻚㻌⏬ീデ᩿Ꮫ䚷㻌䚷㻌㻝㻙㻝㻌⑓⌮⏬ീデ᩿Ꮫ

㻞㻟
㻞㻠
㻞㻡 Ꮫ
㝿
㻞㻢 ᛂ
⏝
㻞㻣 ⛉
┠
㻞㻤

ᐇ
⩦
ཬ
䜃
⑓
㝔
ෆ
◊
ಟ

䚷䚷䚷㻝㻙㻞㻌ᨺᑕ⥺⏬ീデ᩿Ꮫ䚷䚷䚷㻝㻙㻟㻌䠩䠮䠥⏬ീデ᩿Ꮫ

㻝 ⩚㈡
㻝

⚟ᒣ
⚟ᒣ

䠆䚷㻞㻚㻌ప౵く἞⒪Ꮫ㻌㻝 ᮌᮧ๛䞉㧗ᢡ䠆䚷㻟㻚㻌⏕యᮦᩱᏛ䞉ேᕤ⮚ჾᏛ㻌㻝 ⏣⏿䞉ᯇ⏣⚽䠆䚷㻠㻚㻌་⒪᝟ሗᏛ

㻝 㯮⏣

㻞㻥

䠆䚷㻡㻚㻌᳨ᰝᶵჾᏛ䞉◊✲ᶵჾᏛ㻌

㻝 ୍ᒣ

㻟㻜

䠆䚷㻢㻚㻌་⒪䞉⏕άᨭ᥼䝅䝇䝔䝮Ꮫ 㻝

᳝ྡ

㻝

ᚲಟ
䠕᭶䡚

㻟㻝 䚷䚷䚷ศ㔝ᶓ᩿ᆺ኱Ꮫ㝔ᩍ⫱䝁䞊䝇་Ꮫ◊✲⛉ᩍဨ

་⛉Ꮫᑓᨷ௨እ
᥎ዡ⛉┠㻟㻞 䚷䚷䚷ⱥㄒ䚷䡀䡁䠾䠽䡐䡁䚷䊢㻭㼘㼠㼙㼍㼚㼚

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⥙᥃䛡䛿ᒚಟᏛᖺ䞉Ꮫᮇ䚸ᩘᏐ䛿༢఩ᩘᏛ㝿ᛂ⏝⛉┠䛿䚸ㅮ⩏ཬ䜃ᐇ⩦䛾୧᪉䜢ཷㅮ䛧䛺䛔䛸༢఩䛿ㄆ䜑䜙䜜䛺䛔䚹㻖㻝㻌▷ᮇᾏእ䜲䞁䝍䞊䞁䝅䝑䝥䜎䛯䛿௻ᴗ䞉බⓗᶵ㛵䜲䞁䝍䞊䞁䝅䝑䝥䛾䛹䛱䜙䛛䜢㑅ᢥ䛧䚸ᚲ䛪ಟᚓ䛩䜛䛣䛸༤ኈᚋᮇㄢ⛬䛷䛾ᚲಟ༢఩ᩘ䚷䠎༢఩㻖༳䛾⛉┠䛿䚸᥎ዡ⛉┠1. Human Anatomy
Instructors㸸Masatoshi Hagiwara(Professor, Dept. Anatomy and Developmental Biology)
Shigeto Yamada(Professor, Graduate School of Human Health Sciences)
Takeshi Sakurai(Program-Specific Professor, Graduate School of Medicine)
The human anatomy course is a basic subject offered to the second year LIMS students.
Understanding human body, its structure and function in detail, is crucial for research
and application in medico-engineering collaborative projects.
lectures and labs.

The course consisted of

In the lectures, we used the active learning methods in which

students presented the summary of the contents of the textbook for each organ systemand discussed the related issues to deepen their understanding of the human body.

Inthe lab, students were encouraged to observe and touch the cadaver in order to haveimages of three-dimensional arrangement of the human body using handouts which the
instructors prepared for as a guide. We stressed the concept that functions aresupported by structures and that issues and restrictions of functions are determined by
the structural organizations. Students were asked to submit the report for each lab on
the content observed in the class.

An important feature of the program is to offer the

LIMS students an experience of studying human anatomy in a similar way as
medical/co-medical students do.

2. English Debate Course and PracticeInstructor: Christian F. Altmann, Associate Professor (Graduate School of
Medicine)
In 2017, the English Debate course and practice was again held as a weekly course withthe aim to provide students with a wide range of activities and discussion opportunities
in English to widen their viewpoints and hone their communication skills.
First year students were trained in basic argumentation skills, and the presentation ofscientific and societal topics and ideas. They led various discussions, e.g., on life-span
extension and global warming. Some project ideas they presented were changes in the
packaging of medical drugs, more efficient usage of restaurant space, and machinelearning.
The second year students practiced project discussion and debate activities in teams. In
one part of the course, teams of students proposed an idea which was discussed by allstudents. Exemplary topics were the introduction of airplane-like taxis and dry bathproducts. In the latter part of the course, student teams were free to select their topics
and presented for example a controversial murder case or a way to integrate real-time
quizzes into teaching.
Third, fourth, and fifth year students (doctoral level) engaged in discussions withresearchers from a diverse range of research fields (neuro-engineering, medicine,
pharmacology, energy science, etc.) and nationalities (Australian, Belgian, Japanese,
Taiwanese, etc.). This year’s focus was on the application of engineering in medical
imaging.

 Basic Materials Chemistry
Instructors: Teruyuki Kondo(Professor, Advanced Biomedical Engineering   
Research Unit, C-PiER)
Yu Kimura (Program-Specific Associate Professor, LIMS)
In academic year 2017, we tried to have lectures through remote-conference systemboth at Yoshida and Katsura Campus. This trial would be helpful for students to reduceburden of transportation between campuses. In fact, number of students was increasedin this year. About contents of the course, characteristics and synthetic routes of
medicines such as sulfa drug and indinavir were lectured from the viewpoint ofpharmacophore, structure-property relationship, mechanism of action and theirbiodistribution. In contrast, biomaterials as a large bulk material for clinical use have
many functional moieties and characteristic properties, such as bioavailability,
biocompatibility, antithrombogeneity, or other bioactivities, the lecture summarizedthese properties with the explanation in molecular level. In the lecture, we put emphasis
on understanding not only of basic requirements as biomaterial, but also of the reason
why the chemical composition was chosen to use as a biomaterial. The knowledge would
be helpful to design novel materials based on a demand in fruitful healthy-longevity
society. Through the submitting report after the course and the follow-up, we evaluatedstudents on the proficiency and utilizing ability of obtained knowledge. Also a practicein imaging chemical probes on mouse have been executed since academic year 2014.
Together with students, pigment molecules as a probe were injected via tail vein of mice,and the distribution in body was observed with 3-D photoacoustic CT scanner andfluorescence camera-TV monitor. Moreover, dissection of organs and the photoacousitic
and fluorescent imaging was performed together with students. These experiences would
be helpful to prepare further anatomy and physiology courses.

4.  Molecular Analysis of life
Instructors: Yasuo Mori (Professor, Graduate School of Engineering)
Masayuki Mori (Associate Professor, Graduate School ofEngineering,)
Miyuki Nishi (Program-Specific Associate Professor, LIMS)
To understand analytical methods that clarify roles of molecules in controlling
biological functions, fundamental techniques and knowledge will be acquired in thiscourse. The target of this course includes those students who are not familiar to livingorganisms as their subjects of experiments/studies. The course also provides anopportunity to prepare for the later advanced program curriculum of the LIMS
program.
1. Orientation
2. DNA structure and function: check your own genotypes of metabolic enzymes ofalcohol
3. Analysis of cell function by Patch clamp technique
4. Second messenger and thermosensor
5. Cell sorting (BD FACSJazz Cell Sorter)
6. Presentation and Discussion

5.

Biopharmaceutics

Instructor: Kazuhisa Nakayama (Professor, Graduate School of Pharmaceutical
Sciences)
Yoshinobu Takakura (Professor, Graduate School of Pharmaceutical Sciences)
Fumiyoshi Yamashita (Professor, Graduate School of Pharmaceutical Sciences)
Yuriko Higuchi (Senior Lecturer, Graduate School of Pharmaceutical Sciences)

This lecture toward “Biopharmaceutics” was provided to 2nd-graders. In this lecture, we
introduced the anatomical and physiological characteristics of tissues in the body tounderstand drug disposition processes, including absorption, distribution, metabolism,and excretion. Then, we explained the mechanisms of drug disposition in each process,and provide the basic concept and its application example of drug delivery system (DDS).
The lecture of modeling and simulation of drug distribution by Prof. Yamashita wasnewly added in this year.
1. Introduction of pharmacokinetics and drug delivery system
2. Physicochemical factors in transfer drugs across membrane
3. Drug absorption, bioavailability, and routes of administration
3-1Absorption from GI tract
3-2Transdermal absorption
3-3Parenteral injection
3-4Pulmonary absorption
4. Excretion of drugs
5. Metabolism of drugs
6. Evaluation of drug absorption from GI tract, renal or biliary excretion of drug
7. Pharmacokinetics
8. Exercise of the clearance analysis
9. Determinats of drug distribution
10.Drug delivery system for nucleic acid drugs
11.Pharmacokinetics and its targeted regulation
12.Drug delivery system for cell-based medicine

6. Basic Mathematics
Instructor:

Nobuyuki Higashimori (Program-Specific Senior Lecturer, LIMS)

This lecture provides basic materials of calculus and linear algebra at first-year
undergraduate level for students who have once learned these materials and for those whohave not. Main topics arez Differential and integral calculus in one and several variables,z Ordinary differential equations,z Extremum problems including Lagrange’s multiplier method,z Operations on matrices and solution of simultaneous linear equations,z Basic concepts in abstract linear space theory,z Eigenvalue problems,z Fourier series and Fourier transform
These knowledge and concepts will be helpful for students who take more advanced
lectures such as basic physics and for those who want to use mathematical modeling forunderstanding various phenomena they are interested in.

7. Applied Mathematics
Instructor:   Nobuyuki Higashimori (Program-Specific 
SeniorLecturer, LIMS)

This course introduces basic concepts in mathematical statistics. This course is an
introduction to mathematical statistics. The purpose is to learn elementary parts ofmathematical methods for appropriate inference from experimental data. The goal is tounderstand the meaning of statistical inference at the level of this course and tomanipulate simple examples. Main topics are as follows:z Random variables and distributionsz Sampling distributions (t, chi-squared, and F distributions)z Point and interval estimationz Parametric hypothesis testingz Simple regression analysisz Nonparametric testing problems

8. Minimally invasive therapy
Instructors:
Takeshi Kimura (Professor, Department of Cardiovascular
Medicine)
Shinji Uemoto (Professor, Department of Hepato-BiliaryPancreatic Surgery and Transplantation)
Yoshiharu Sakai (Professor, Department of Gastrointestinal Surgery)
Osamu Ogawa (Professor, Department of Urology)
Kyoichi Takaori (Program-Specific Associate Professor,
LIMS)
Lectures and practical seminars about minimally invasive therapies havebeen given by Doctors Mistuhiro Nakamura, Naritatsu Saito, Shigeru

Tsunoda, Takayuki Kikuchi, Yoshiki Arakawa, Takahiro Inoue andKyoichi Takaori.
Lectures included “Minimally invasive surgery in hepato-biliary-pancreaticsurgery and transplantation (orientation inclusive)”, “Minimally invasive
surgery for digestive diseases”, “Minimally invasive therapies inneurosurgery”, “High precision radiation therapy for cancer”, “Intravascularcatheter treatments in cardiovascular medicine”, “Minimally invasive surgery inurology” and these lectures were given at the Kyoto University Hospital.

First, the attendants of the course r e c e i v e d a n o r i e n t a t i o n a t t h e
o p e r a t i o n t h e a t e r o f Kyoto University Hospital. Subsequently, during thecourse of “Minimally invasive surgery for digestive diseases”, the attendants
experienced laparoscopic surgery by themselves with a simulator at the Kyoto
University Hospital and observed procedures of gastrointestinal surgery at theoperation theater of the Kyoto University Hospital later on. Other courses
consisted of following contents:“Minimally invasive therapies in neurosurgery”: observation of intravasculartherapies for brain vascular diseases.
“High precision radiation therapy for cancer”: simulation of radiation therapy planning.
“Intravascular catheter treatments in cardiovascular medicine”: observationof intravascular therapies for ischemic heart diseases.
“Minimally invasive surgery in urology”: observation of a robotic prostatectomy.

9.

Pre-research rotation

Starting this year, students have two options for Pre-research rotation. Laboratory
Practice Course was performed in the similar manner as last year, and this year we
introduced hospital practice in the following manner.
(1) Laboratory Practice Course for advanced research equipment.
xAll students (L1, L2 and L3 transfered) must attend the course. This is a part ofmandatory pre-research.

xStudents attend four practices (laboratories) every year, each is three hours.

x

Each practice has specific goals that you have to achieve.

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1. Principle and application of confocal
microscope (Anatomy and Developmental
Biology,

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5HODWHG'LVHDVHV*UDGXDWH6FKRRORI0HGLFLQH >-XO\@(2) Hospital Practice
We cooperated with the Department of
Human Health Sciences at the Faculty of
Medicine from this fiscal year, and organizeahospital practice course.
x

Outpatient Clinic DayxOne day out of 8/4, 7, 8, 9am~12pm,
One student, or one Japanese and one
foreign student, will accompany apatient and experience a day in theoutpatient ward.

x

Department Visitx

8/1 14:00—15:00 Diagnostic Pathologyx

8/2 14:00—15:30 Clinical Laboratory +Transfusion

Medicine

and

Cell

Therapyx

8/8

14:00—15:15

ClinicalPharmacology and Therapeuticsx

8/9 14:00—15:00 Medical Information
Technology&

Administration

Planningx

8/9

15:00—16:00

ClinicalRecordManagement Unitx

Summery and Discussionx

8/11 1:00 pm— Human Health Science
students will make their presentation
English.

in

LIMS students will thenmake one 5-minute presentation.

10. Genome Cohort Study
Instructor: Meiko Takahashi

Project-specific Senior Lecturer (LIMS)“Genome Cohort Studies” provides an intensive overview of genomic epidemiology forstudents intending to engage in, collaborate in, or interpret the results of genomic andepidemiologic research. This course was started in April 2014 and is available for all
second year Master’s degree students. Through lectures and group discussions, students
will be able to understand the essential roles genomic analyses will play in 21st Century

medicine - the era of "preventive medicine".
The course covers the following topics:(1) Research fields and novel techniques developed that have emerged in the years sincecompletion of the Human Genome Project.
(2) Understanding the importance of medicine and genomic research.
(3) What is a “cohort”? Comprehend the differences between cohorts and case-control
analyses, and appreciate the strengths and weaknesses of the various types of analyses.
(4) Acquiring basic knowledge of the latest technologies used in genomic medicine.
(5) Introduction to the different techniques used in bioinformatics and proteomics, aswell as how to handle web-based public databases.

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ᅗ1ṇᖖ࡞ BRCA1 ࡟ࡼ                       ࡿ DNA ᩿⿣ࡢಟ᚟㻌⣽⬊⏕Ꮡ㻌     ዪᛶ࣍ࣝࣔࣥῧຍ                                          DNA㻌DNA ᩿⿣㻌                       Ⅼኚ␗ࢆྵࡳಟ᚟

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  ዪᛶ࣍ࣝࣔࣥ౫Ꮡⓗ࡞ DNA ᩿⿣ಟ᚟⬟ࡢపୗࡋࡓ BRCA1 Ⅼኚ␗ࡢ☜ㄆ  ඛ⛬࡜ྠᵝ࡟⣽⬊࡟ዪᛶ࣍ࣝࣔࣥࢆ᭚㟢ࡉࡏࠊᩘ᫬㛫ᚋ࡟⣽⬊ࢆᅇ཰ࡋࠊሷ໬ࢭࢩ࣒࢘⁐ᾮ໙㓄ࢆ฼⏝ࡋ࡚ᐦᗘ࡟ᛂࡌ࡚≀㉁ࢆศࡅࡿࠋࡑࡢᚋࠊᢠࢺ࣏࢖ࢯ࣓࣮ࣛࢮᢠయࢆ⏝࠸ࡓ࢚࢘ࢫࢱࣥࣈࣟࢵࢺἲ࡟࡚ࠊࢺ࣏࢖ࢯ࣓࣮ࣛࢮࢆ᳨ฟࡍࡿࠋBRCA1 ࡟Ⅼኚ␗ࢆྵࡳ᪂ᶵ⬟ࡢపୗࡋࡓ⣽⬊ࡢ᪉࡟ࡣࠊࢺ࣏࢖ࢯ࣓࣮ࣛࢮࡀࠊ㔝⏕ᆺ⣽⬊࡜ࡣ␗࡞ࡿ఩⨨࡟᳨ฟࡉࢀࡿࠋࡇ
ࢀࢆ฼⏝ࡋ࡚ࠊࡑࡢⅬኚ␗ࡀ BRCA1 ࡢᶵ⬟పୗࡋ࠸࡚ࡣⓎࡀࢇ࡟⧅ࡀࡿ࠿࡝࠺࠿ࡀᐃᛶⓗ࡟☜ㄆ࡛ࡁࡿ(ᅗ 2)ࠋඛ⛬࡜ྠᵝ࡟ࠊࡇࡢᐇ㦂ࢆ⾜࠺ࡓࡵࡢணഛᐇ㦂ࢆ 2017 ᖺ࡟⾜ࡗ࡚࠸ࡓࠋ                       ᅗ 
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These days, Malignancies and leukemia are theisolated from peripheral blood NK (PB-NK) cells

top rate cause of dead in Japan. To prolong life

(Fig. 4)span, it is important to focus on these diseases.
There are some trials like born mallow
transplantation or cord-blood transplantation or
anticancer-drug to treat them. Since the relapse
rate and side effect are high under there trials,
natural killer (NK) cells are new candidate
sourcesforimmunotherapies

invariousmalignancies and leukemia. NK cells are a one of

Figure 4: Morphology of NK cellV

innate lymphocytes and show cytotoxicity

PB-NK cells showed 49.65 ± 3.46% of killingagainst tumor cells without prior antigen specificactivity against K562 target cells, while the killing

stimulation. More recently, NK cells induction

potential of PSC-derived NK cell’s showed killingfrom human pluripotent stem cells (hPSCs),

potential against K562 cells (medium A: 25.4 ±taking the advantage of their unlimited growth

5.52%, medium B: 23.25 ± 9.26%) which waspotential, has been reported. Although previous

slightly lower than that of PB-NK cells (49.65 ±studies regarding hPSC-derived NK cells seems

3.46%)In conclusion, we successfully induced

impressive and successful, most systems used afunctional NK cells from hPSCs under chemicallybovine and human serum, which might result in

defined condition (Fig. 5)

the unstable yield and efficiency in the
production of HPCs and NK cells.
To resolve those problems, we tried to induce
functional NK cells from hPSCs under acompletely chemically defined condition freefrom any non-autologous serum or stroma.
First, we collected hematopoietic progenitorsfrom hPSCs using magnetic activated cell sorting,
we cultured them with NK inducing cytokines. At
this point, we selected two media. We compared

Figure 5: .LOOLQJDFWLYLW\

serum-containing medium A and chemically

They showed compatible phenotype to PB-NK

definedcells in terms of morphology, surface marker andmediumB

byevaluatingthedifferentiation efficiency and function of NK cells. cytotoxicity.

They

were

expectedtobe

On Day 48, the frequency of CD56 positive cells

applicable not only to immunotherapy but also

showed no significant differences between two

to model studies of the NKC associating diseases.

media. In both conditions, NK cells expressed NK,QWKHIXWXUHXVLQJK36&1.FHOOVZHZDQWWREH

specific receptors. hPSC-derived NK cells showed

HVWDEOLVKthe compatible size and morphology to NK cells                 malignancies and leukemia.

QHZ

WUHDWPHQWDJDLQVW

variousComposite category (Life science & health), Selected on FY2012

Chemically defined productionof natural killer cells
from human pluripotent stem cells

3KRWR

Training program of leaders for integrated medical system
Kyoto University

Hiroyuki Matsubara
Background and Objective
Natural killer cells (NKCs) have been proposed as a new source for immunotherapies in various malignancies. Previous studies have developed peripheral
blood NKC expansions or NKC differentiation from cord blood cells. More recently, NKC inductions from pluripotent stem cells (PSCs), taking the advantageof their unlimited growth potential, were reported. However, due to the usage of xeno- or allo-derived components, there are various impediments to theclinical applications of those methods in the aspects of safety and reproducibility. To resolve those problems, we tried to induce functional NKCs from PSCs
under a completely chemically defined condition free from any non-autologous serum or stroma.

CD34+/CD45+ Hematopoietic progenitor cells are emerged in conventional 2D method
conventional 2D method

MediumMatrixIC

CD45-FITC

CD34-PE
Schema of hematopoietic progenitor cell (HPC) differentiation
Simply changing cytokine combinations (BMP4, VEGF, SCF, Flt3L)
and chemically defined media in step-wise manner.

Day10~12

CD34-PE

Cytokine

Day 2
Day 4
Day 12
SCF
SCF
BMP4
VEGF
Flt-3
VEGF
DMEM-based defined medium
iMatrix-coated culture dish

Day4

Day2

KDR-APC

Day 0

IC

Lateral mesodermal cell marker, KDR, is expressed over 80%.
Representative flow cytometry plots at day2 and 4.

HPC markers, CD34 and CD45,
were expressed on day10-12.
CD34+CD45+ progenitor cells were enriched at day10~12.
Representative flow cytometry plots at day10.

Chemically defined condition can induce NKCs from PSC-derived HPCs
Day10~12
Meso

PSC

HPC
3 weeks

Mye

NKC

50 μm

DMEM + Serumor

SCF + FL +IL-7 + IL-15

PSC-derived CD56+ NKCs
DMEM + Serum
Activatory NKR
Inhibitory NKR
CD161 CD94 CD159a NKG2D NKp44 NKp46

Stem Line II

DMEM + Serum

Peripheral blood
CD56+ NKCs

PSC-derived CD56+ NKCs

Stem Line II
Schema of Natural killer cell (NKC) differentiation
PSC, Pluripotent stem cell; Meso, Mesoderm;
Mye, Myeloid; NKC, Natural killer cell

Stem Line II

Morphology of PSC or PBMC-derived NK cells
Representative cytospin of Giemsa-stained NK cells (Bar=50μm,
white arrow=azur granules) Cytospin was prepared from PSC-derived NK cells
at Day48 and healthy control NK cells.

Surface marker of NK cells
PSC-derived NK cells expressed NK-specific receptors.
Representative data at day 48.

PSC-derived NK cells show killing activity against K562
HPC

Mye

100

NKC

N=1

91.3%

Percent of Killing

PKH+DAPI+
MACS

CD56

CD56+ cells

PKH+DAPI-

80
60

42%

40
21.5%

3.7%

16.7%

20

FSC
PKH

37Υ
Υ 4hrsDAPI
PKH-labeled K562 cells

0
K562
NKC

1.0 1.0 1.0
Nil PC 1.0

1.0 1.0 1.0
2.0 5.0 1.0

DMEM + Serum

1.0 1.0 1.0 1.0 1.0 î104
2.0 5.0 1.0 2.0 5.0 î104

Stem Line II

PSC-derived CD56+ NKCs
Scheme of cytotoxicity assay
At day48, NK cells are corrected using auto-MACS. PKH-labeled leukemia cell line K562 co-culture with NK cells
for 4 hours at 37Υ, and analyze on the number of DAPI+ cells as a cytotoxicity of NK cells using FCM.

Peripheral blood
CD56+ NKCs

Killing activity of NK cells from PSC or PBMC against K562
PSC-derived NK cells lysis K562 cells similarly to PBMC-derived NK cells.

Conclusions
We successfully induced functional NKCs from PSCs under chemically defined condition. They were expected to be applicable not only to
immunotherapy but also to model studies of the NKC associating diseases.

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2017/07/01-08/31@Hans Knöll InsƟtute (Jena, Germany)(Specialize to natural products from micro organisms and infecƟon biology of pathogenic fungi)
Purpose
1. Experience pracƟcal research (drug discovery)
2. Explore the future career
Internship@ Department of Molecular and Applied Microbiology
1. Design geneƟc constructs and transform them into Aspergillus nidulans
2. Isolate secondary metabolites from A. nidulans and idenƟfy them with LC-MS/MS
Aspergillus Nidulans

䖩Supervisor
䞉Supported me perfectly䞉Gave me opportunity to learn what I want as muchas possible
䞉Trusted on me䞉Tried to let me in a group
䖩Achievement
I learned
With Beni (my supervisor)
䞉a mindset of pracƟcal research
䞉technics (extracƟon of metabolites, proteome
analysis and screening of candidate compounds)
䖩 BeneĮts
䞉Experienced and Think of well work-life balance䞉Spend free two months
䞉Connect with researchers in other countries
䖩 Future CareerConƟnue researching as a postdoc abroad

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Functional analysis of TIARP as anti-inflammatory signal protein䚽Ᏹ㔝 㞞ಇ1,2
1. ி㒔኱Ꮫ኱Ꮫ㝔 ᕤᏛ◊✲⛉ ศᏊᕤᏛᑓᨷ ⏕యศᏊᶵ⬟⛉Ꮫㅮᗙ ༤ኈㄢ⛬2ᖺ
2. ༤ኈㄢ⛬䝸䞊䝕䜱䞁䜾䝥䝻䜾䝷䝮 ඘ᐇ䛧䛯೺ᗣ㛗ᑑ♫఍䜢⠏䛟⥲ྜ་⒪㛤Ⓨ䝸䞊䝎䞊⫱ᡂ䝥䝻䜾䝷䝮 L4

ᴫせᑓᨷ䛷䛾◊✲

㛵⠇䝸䜴䝬䝏䛿⁥⭷⅖䚸㛵⠇ᶵ⬟䛾◚ቯ䚸඲㌟ᛶ䛾៏
ᛶ⅖⑕཯ᛂ䛺䛹䜢୺⑕≧䛸䛩䜛⮬ᕫච␿⑌ᝈ䚸⭺ཎ⑓䛾1䛴䛷䛒䜚䚸᪥ᮏᅜෆ䛷䜒⣙70୓ே䛾ᝈ⪅䛜Ꮡᅾ䛩䜛
Common disease䛾1䛴䛷䛒䜛䚹ᚑ᮶䛿἞⒪䛜㠀ᖖ䛻㞴䛧䛔⑌ᝈ䛾୍䛴䛷䛒䛳䛯䛜䚸㏆ᖺ䛿⅖⑕ᛶ䝃䜲䝖䜹䜲䞁䛾ᶵ⬟䜢ᢚ䛘䜛Infliximab (ᢠTNF-αᢠయ) 䜔
Tocilizumab (ᢠIL-6Rᢠయ) 䛺䛹䛾⏕≀Ꮫⓗ〇๣䛻䜘䛳䛶ዌຌ⋡䛿኱䛝䛟ྥୖ䛧䛯䚹䛧䛛䛧๪స⏝䜔⤒῭ⓗ㈇ᢸ
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TIR

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Vu N. Ngo et.al., Nature, 2011

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◊✲⫼ᬒ
㼲 TIARP䛾ᶵ⬟䛸㢮⦕య䛾ᵓ㐀

㼲 ⅖⑕ᛶ䝃䜲䝖䜹䜲䞁䝅䜾䝘䝹䛸ᢠ䝸䜴䝬䝏⸆䛾㛵ಀ㼲 㛵⠇䝸䜴䝬䝏䛾⑕≧䛸ᇶ♏᝟ሗᢠ䝸䜴䝬䝏⸆

Tocilizumab

Infliximabᇶᮏ᝟ሗ䝃䜲䝖䜹䜲䞁

TNF-α⭷䝍䞁䝟䜽㉁TNFR

䞉䜰䝭䝜㓟ṧᇶᩘ䠖470

IL-6

䞉ศᏊ㔞䠖52.994 kDa䞉ศ㢮䠖6ᅇ⭷㈏㏻ᆺ
⭷䝍䞁䝟䜽㉁

TIARP

IL-6R

䞉ᶵ⬟䠖Fe3+䛾㑏ඖ䞉㓄ิ┦ྠᛶ
䠖Human-Mouse-Rat䝸䞁㓟໬㓝⣲

IKK

㌿෗ᅉᏊ

NF-κB

Jak1

Iain B. M. et al. N. Engl. J. Med. (2011)?

䞉㛵⠇䝸䜴䝬䝏䛾⑓≧䛾≉ᚩ䛸䛧䛶ච␿⣔䛻䛚䛔䛶⅖⑕䜢䝁䞁䝖䝻䞊䝹䛩䜛≀㉁䛷䛒䜛
䝃䜲䝖䜹䜲䞁䛾␗ᖖ䛺άᛶ໬䛜ᣲ䛢䜙䜜䚸᪤Ꮡ䛾ᢠ䝸䜴䝬䝏ᢠయ⸆䛿⅖⑕άᛶ໬䜢ᢸ䛖
TNF-α/NF-κB䝅䜾䝘䝹䛛IL-6/STAT3䝅䜾䝘䝹䛾䛹䛱䜙䛛䜢ᢚไ䛩䜛䛣䛸䛷ᶵ⬟䛧䛶䛔䜛䚹ᐇ㦂⤖ᯝ᭱㏆䛾ືྥ䛸ண᝿䝰䝕䝹㼲ᢠTIARPᢠయ䛻䜘䜛䠳䠞䛷䛾᳨ฟanti-TIARP
(ᕷ㈍ရ)

72
55

43

72
55

36

43

28

36

250
130
95

43
36
28

17

17

㼲TIARP-Exon 3 Splicing variant㼲㟁Ẽ✸Ꮝἲ䛻䜘䜛RAW264.7⣽⬊䜈䛾㑇ఏᏊᑟධගᏛ㢧ᚤ㙾ീ

anti-TIARP(ཷク⏕⏘ရ)MW/kDa
250
130
95
72
55

MW/kDa䞉TNF-α Induced Adipose Related Protein (TIARP)䛿
㏆ᖺ䚸ᢠ䝸䜴䝬䝏స⏝䛜Ⓨぢ䛥䜜䛯⭷䝍䞁䝟䜽㉁䞉㏆ᖺ䛻䛺䛳䛶IL-6/STAT3䝅䜾䝘䝹䜢ᢚไ䛩䜛ᶵ⬟䜒ᣢ䛴䛸ሗ࿌䛥䜜䛯䛜䚸䛣䛾ᶵ⬟䛻䛴䛔䛶䛾ศᏊᶵᵓ䛿୙᫂
䞉TIARP䛜┤᥋IL-6/STAT3䝅䜾䝘䝹䛻ᐤ୚䛧䛶䛔䜛䛸䛿⪃䛘㞴䛟䚸௰௓䛩䜛ఱ䜙䛛䛾ศᏊ䛜Ꮡᅾ䛩䜛䛸⪃䛘䜙䜜䛯䚹э௰௓䛩䜛ศᏊ䜢ච␿ඹỿ㝆ἲ䛷᥈⣴䛩䜛䛣䛸䛻䛧䛯䚹⅖⑕཯ᛂ䞉㛵⠇䝸䜴䝬䝏䛿㛵⠇䛷䛾⅖⑕䜢୺⑕≧䛸䛩䜛⮬ᕫච␿⑌ᝈ
䞉⑓≧䛜㐍⾜䛩䜛䛸㛵⠇䛜◚ቯ䛥䜜QOL䛜኱䛝䛟పୗ䛩䜛䞉ᅜෆ䛷䛾ᝈ⪅ᩘ䛿⣙70୓ே䠄᭷⑓⋡ 0.5Ң1.0䠂䠅䞉⏕≀Ꮫⓗ〇๣䛻䜘䜛἞⒪䛜᭷ຠ䛰䛜䚸⸆౯䛜㧗䛔anti-FLAG(Control)Mark D. K. et al., J. Biol. Chem. (2015)STAT3

TIARP-FL э 㕲䜲䜸䞁㑏ඖ㓝⣲

GFP-⺯ගീFe3+

TIARPΔNBD эᢠ⅖⑕䝅䜾䝘䝹

Fe2+

IL-6

MW/kDa250
130
95

TIARP-TM1-6

TIARPΔNBD

IL-6R

AISP-XTIARP-NBD

Jak1

28

NADPH

17

䞉ᐇ㦂䛻䛚䛔䛶TIARP䜢䜴䜶䝇䝍䞁䝤䝻䝑䝔䜱䞁䜾(WB)䛷
᳨ฟ䛩䜛䛯䜑䛾ᢠయ䜢㉎ධ䛧䛯䛜䚸ᕷ㈍ရ䛿඲䛶㠀≉␗྾╔䛜㓞䛟᳨ฟ䛷䛝䛺䛛䛳䛯䚹э䜶䝢䝖䞊䝥䜢タィ䛧䚸እ㒊Ⓨὀ䛷᪂䛯䛺ᢠయ䜢సᡂ䛧䛯䚹䞉䝸䜴䝬䝏ᝈ⪅䛷TIARP䛾Ⓨ⌧䛿䝬䜽䝻䝣䜯䞊䝆䛷ぢ䜙䜜䛯䛾䛷䝬䜽䝻䝣䜯䞊䝆䛾⣽⬊ᰴRAW264.7䜢⏝䛔䛶ᐇ㦂䛩䜛䛣䛸䛻䛧䛯䚹
䞉RAW264.7䛿㠀ᖖ䛻㡹୔䛺⣽⬊䛷䚸Lipofectionἲ䛷䛿㑇ఏᏊᑟධ䛜ฟ᮶䛺䛔䛯䜑㟁Ẽ✸Ꮝἲ䜢⏝䛔䛯䚹э㑇ఏᏊᑟධ䛿ฟ᮶䛯䜒䛾䛾ຠ⋡䛿50%⛬ᗘ䛻␃䜎䛳䛯

NADP+

?

STAT3

䞉⣽⬊㉁ෆ䛾NADPH⤖ྜ䝗䝯䜲䞁(NBD)䛜Ḟᦆ䛧䛯Exon 3 splicing variant (ΔNBD)䛜
Ꮡᅾ䛩䜛䛣䛸䛿☜ㄆ䛥䜜䛶䛔䛯䛜䚸ΔNBD䛜ᢠ⅖⑕స⏝䜢᭷䛧䛶䛔䜛䛸᭱㏆ሗ࿌䛥䜜䛯䚹
эNBD䛿TIARP䛾⭷㈏㏻䝗䝯䜲䞁(TM)䛾┤ୗ䛻Ꮡᅾ䛩䜛䛾䛷䚸ᢠ⅖⑕స⏝䝅䜾䝘䝹䜢άᛶ໬䛥䛫䜛TIARP⤖ྜ䝍䞁䝟䜽㉁(AISP-X)䜢㜼ᐖ䛧䛶䛔䜛䛾䛷䛿䛺䛔䛛䛸ண᝿䛥䜜䛯䚹䛭䛾௚䛾LIMS䛷䛾άື䠖䜲䞁䝍䞊䞁䝅䝑䝥㼲䠄ᰴ䠅ᮾ䝺ᇶ♏◊✲䝉䞁䝍䞊䛷䛾䜲䞁䝍䞊䞁䝅䝑䝥㼲Pull down assay䛸䜲䞁䝍䞊䞁䝅䝑䝥䛷䛾ᡂᯝ
7KURXJK

7KURXJK

%LQG

%LQG

䞉䜲䞁䝍䞊䞁䝅䝑䝥䛷䛿Pull down assay䜢⏝䛔䛯㛤Ⓨ୰䛾ೃ⿵໬ྜ≀䛻⤖ྜ䛩䜛ᮍ▱䛾䝍䞁䝟䜽㉁䜢ྠᐃ䛩䜛ᐇ㦂䜢⾜䛳䛯䚹© Toray Industries, Inc.

䞉⏘Ꮫ༠ാ䜲䝜䝧䞊䝅䝵䞁ேᮦ⫱ᡂ༠㆟఍(C-ENGINE)䛾
䜲䞁䝍䞊䞁䝬䝑䝏䞁䜾䝅䝇䝔䝮(IDM)䜢௓䛧䛶䚸䠄ᰴ䠅ᮾ䝺ᇶ♏◊✲䝉䞁䝍䞊་⸆◊✲ᡤ䛻䛚䛔䛶1䞄᭶㛫䛾䜲䞁䝍䞊䞁䝅䝑䝥䜈ཧຍ䛧䛯䚹௒ᚋ䛾ணᐃ[1] 䝺䝖䝻䜴䜲䝹䝇䜢⏝䛔䛯TIARP/TIARPΔNBDᏳᐃⓎ⌧RAW264.7⣽⬊ᰴ䛾సᡂ
[2] ኳ↛≧ែ䜢⥔ᣢ䛧䛯䜎䜎䛷䛾⣽⬊◚○ᾮ䛾ㄪ〇᪉ἲ䛾᮲௳᳨ウ[3] ඹච␿ỿ㝆ἲ䛸㉁㔞ศᯒἲ䛻䜘䜛AISP-X䛾ྠᐃ
[4] AISP-X䛾ᶵ⬟ゎᯒ䞉⌮ㄽୖ䛿ᕥᅗ䛾䜘䛖䛻ศ㞳䛷䛝䜛䛜䝡䞊䝈䜈䛾㠀≉␗྾╔䛜ከ䛟䚸ศ㞳⬟䛜Ⰻ䛟䛺䛔䛣䛸䛜ၥ㢟䛸䛺䛳䛶䛔䛯䚹䞉䝡䞊䝈䜈㠀≉␗྾╔䛩䜛ᛶ㉁䜢㏫⏝䛧䚸ΰྜᾮ䛻໬ྜ≀ಟ㣭䜢᪋䛧䛶䛔䛺䛔䝡䞊䝈䜢཯ᛂ䛥䛫䛶୙⣧≀䜢ྲྀ䜚㝖䛔䛯ᚋ䛻Pull down assay䜢⾜䛖䛸䛔䛖ᡭἲ䜢ᥦ᱌䛧䚸ᐇ㝿䛻ศ㞳⬟䛾ᨵၿ䛻ᡂຌ䛧䛯䚹

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Fig. 1. Microbial communities are changed in aging.
Compositions of microbiota in 0, 5, 11, 24, 36 days old flies.

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100%

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80%

Survival rate

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60%
40%
20%
0%
0

10

20

30

40

50

60

70

80

90

100 110 120

Age (Days))LJ(QYLURQPHQWDOWHPSHUDWXUHDIIHFWVOLIHVSDQ6XUYLYDOFXUYHVRIIOLHVUHDUHG DW Q  PHGLDQVXUYLYDO
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7KHVH EDFWHULD PD\ KDYH LPSRUWDQW UROH IRUWKHGHWHUPLQDWLRQRIOLIHVSDQStudy on age-related disease and gut microbiome
Graduate School of Engineering, Department of Synthetic and Biological Chemistry, L5, Takuto Suito

0. Abstrast
Microbiota is known to play important roles in host metabolism, immune development, intestinal homeostasis, and neurological function. Several studies
indicated that the composition of the microbiota was influenced by aging. In this study, I researched the relationship between change in microbiota andage-related disease from various point of views. In the study at graduate school, commensal bacteria affects energy metabolism and thermoregulatory
system in Drosophila, suggesting that this mechanism is involved in the age-related changes in energy metabolism in human. In LIMS activity, I researchedabout how aging affects the composition of microbiota and how these changes affect the alteration of energy metabolism seen in elderly people. For the
analysis of the molecular mechanism, I learned the assay of mitochondrial respiratory chain in the LIMS internship at University of Texas. In conclusion, my
research will give the novel insight of the relationship between microbiota and energy metabolism in aging.

LIMS research

1. Aging-related microbiota change

2. Aging-related disease and energy metabolism

 Microbiota in old age

 Changes of microbiota
and energy metabolism

Young
People(28-46 y.o.)ElderyPeople≧65y.o.

Bacteroidetes

Firmicutes

Proteobactera

 Hallmarks of aging

Lean

Obesity

Bacteroidetes↑
Firmicutes↓

Bacteroidetes ↓Firmicutes ↑C: Centenalian (99-104 y.o.)
E: Eldery (63-76 y.o.)
Y: Young adult (25-40 y.o)OthersClaesson, M. et al. (2011) PNAS 108, 4586

Biagi, E. et al. (2010) PLoS One 17, e10667

 The composition of gut microbiota are changed in aging.
 Centenarians have characteristic microbiota.

SCFA
etc.
Energy harvest↓
Energy harvest↑
Energy metabolism↑ Energy metabolism↓
Fat accumulation↓ Fat accumulation↑

Relationship between microbiota and Lifestyle

Carlos, L. O. et al. (2013) Cell 153, 1194

 Lifestyle and medication affectmicrobiota of elderly subjects.

 Dysfunction of mitochondria andage-related disease

Integrated understanding of
the mechanism of thechanges in microbiota andenergy metabolism in aging

Jeffery, I. et al. (2016) ISME J. 10, 170

Graduate school research

 Metabolic syndrome Parkinson's disease Reducing basic metabolic rate (BMR)
and hypothermia
 Alterations of microbiota inducechanges in the energy metabolism
 Dysfunction of mitochondria is related
to the several age-related disease

3. Internship activity~functional activity of
mitochondrial respiratorycomplex~

1. Study on the relationshipbetween microbiota andenergy metabolism in Drosophila
Research theme at Graduate School“Molecular mechanism of commensal
tion”
bacteria mediated behavioral thermoregulation”

InternshipPlace: University of Texas Medical School(Houston, TX, USA)
Willian Dowhan Laboratory

Commensal bacteria
Temperature gradientAgarose gel
COLD
Aluminum plate

Partier device

Research theme“Reconstitution and assaying the activity of respiratory complex”

Amino acid

Takeuchi et al., Science (2009)

Desat1

ControlPeriod: Nov. 6 – Nov. 21, 2017

insulin signalingHOTμ = 19.6

Tor

Ak

Cardiolipin

Lipid metabolism(TG production and degradation)

Bacterial metabolte

Cardiolipin-dependent forming of
mitochondrial supercomplex

Culture of yeast

Energy metabolism(ATP production)

−

+

−

+

−

+

Isolation of
mitochondria

Supercomplex
CIII and CIV
trimerProtein purification
Bacteria freeμ = 23.1

Changes inbehavioral thermoregulation

 Commensal bacteria controls energy
metabolism and thermoregulatory
behavior

Reconstitutionandfunctional assay

anti-CIII

anti-CIII

merge(CIII CIV) Lipid molecules affect the molecular function of the respiratorycomplex in mitochondria.

ᖹᡂ㻞㻥ᖺᗘ㻌ᒚಟ⏕ฟᙇ୍ぴ㻺㼛㻚 Ặ䚷䚷䚷ྡ

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ᖐᏛ᪥

┠ⓗᆅ

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ᕝᓮ་⛉኱Ꮫ䚷་⏝⏕≀◊✲䝴䝙䝑䝖◊ಟ఍䜈ཧຍ䛧䚸䝸䞊䝕䜱䞁䜾䝥䝻䜾䝷䝮◊✲ㄢ㢟䛻㛵䛩䜛ᐇ㦂ᢏ⾡ྲྀᚓ䛾䛯䜑◊ಟ䜢ཷㅮ䛩䜛䚹㻝ᇽୖ䚷ஂ⨾Ꮚ

㻞㻜㻝㻣㻛㻡㻛㻞㻢㻞㻜㻝㻣㻛㻡㻛㻞㻢 ᒸᒣ┴㻌಴ᩜᕷᕝᓮ་⛉኱Ꮫ

㻞㻿㻭㻾㻯㻭䚷㻭㻺㻭㻹㻭㻾㻵㻭䚷㻰㻭㻺㻵㻱㻞㻜㻝㻣㻛㻢㻛㻟

㻞㻜㻝㻣㻛㻢㻛㻟 ኱㜰ᗓ㻌኱㜰ᕷ኱㜰೺ᗣᏳ඲ᇶ┙◊✲ᡤ➨㻟㻝ᅇ㏆␥䜶䜲䝈◊✲఍䞉Ꮫ⾡㞟఍䜈ཧຍ䛧䚸䝸䞊䝕䜱䞁䜾䝥䝻䜾䝷䝮◊✲ㄢ㢟䛻㛵䛩䜛᝟ሗ཰㞟䜢⾜䛖䚹᳃䝜ᐑ䝉䞁䝍䞊

㻟ᇽୖ䚷ஂ⨾Ꮚ

㻞㻜㻝㻣㻛㻢㻛㻟

㻞㻜㻝㻣㻛㻢㻛㻟 ᮾி㒔᪩✄⏣኱Ꮫす᪩✄⏣䜻䝱䞁䝟䝇㻞㻜㻝㻣ᖺᗘ䚷㻵㻭㻱㻿㼀㻱ᾏእ䜲䞁䝍䞊䞁䝅䝑䝥ὴ㐵‽ഛ఍䜈ཧຍ䛧䚸㻸㻵㻹㻿䜲䞁䝍䞊䞁䝅䝑䝥ᐇ᪋䛾䛯䜑䛾᝟ሗ཰㞟䚸ពぢ஺᥮䜢⾜䛖䚹㻠ᇽୖ䚷ஂ⨾Ꮚ

㻞㻜㻝㻣㻛㻢㻛㻣

㻞㻜㻝㻣㻛㻢㻛㻤 ᒸᒣ┴㻌಴ᩜᕷᕝᓮ་⛉኱Ꮫ

ᕝᓮ་⛉኱Ꮫ䚷་⏝⏕≀◊✲䝴䝙䝑䝖◊ಟ఍䜈ཧຍ䛧䚸䝸䞊䝕䜱䞁䜾䝥䝻䜾䝷䝮◊✲ㄢ㢟䛻㛵䛩䜛ᐇ㦂ᢏ⾡ྲྀᚓ䛾䛯䜑◊ಟ䜢ཷㅮ䛩䜛䚹

㻡

ᯇཎ䚷ᘯᖾ

㻞㻜㻝㻣㻛㻢㻛㻝㻞㻞㻜㻝㻣㻛㻢㻛㻞㻜 䜰䝯䝸䜹㻌䝪䝇䝖䞁㻮㼛㼟㼠㼛㼚㻌㻯㼛㼚㼢㼑㼚㼠㼕㼛㼚㻌㼍㼚㼐㻱㼤㼔㼕㼎㼕㼠㼕㼛㼚㻌㻯㼑㼚㼠㼑㼞㻵㻿㻿㻯㻾㻌㻞㻜㻝㻣㻌㻭㼚㼚㼡㼍㼘㻌㻹㼑㼑㼠㼕㼚㼓㻌䛻ཧຍ䛧䚸䝸䞊䝕䜱䞁䜾䝥䝻䜾䝷䝮◊✲䝔䞊䝬䛻㛵䛩䜛᝟ሗ཰㞟䛚䜘䜃䝫䝇䝍䞊Ⓨ⾲䜢⾜䛖䚹

㻢ᇽୖ䚷ஂ⨾Ꮚ

㻞㻜㻝㻣㻛㻢㻛㻝㻠㻞㻜㻝㻣㻛㻢㻛㻝㻠 ᒸᒣ┴㻌಴ᩜᕷᕝᓮ་⛉኱Ꮫ

ᕝᓮ་⛉኱Ꮫ䚷་⏝⏕≀◊✲䝴䝙䝑䝖◊ಟ఍䜈ཧຍ䛧䚸䝸䞊䝕䜱䞁䜾䝥䝻䜾䝷䝮◊✲ㄢ㢟䛻㛵䛩䜛ᐇ㦂ᢏ⾡ྲྀᚓ䛾䛯䜑◊ಟ䜢ཷㅮ䛩䜛䚹㻣ᇽୖ䚷ஂ⨾Ꮚ

㻞㻜㻝㻣㻛㻢㻛㻞㻥㻴㼍㼚㼟㻙㻷㼚㾁㼘㼘㻙㻵㼚㼟㼠㼕㼠㼡㼠㻘㻞㻜㻝㻣㻛㻥㻛㻞 䝗䜲䝒䚷䜲䜶䝘㻌䜸䝷䞁䝎㻭㼏㼍㼐㼑㼙㼕㼏㻌㻹㼑㼐㼕㼏㼍㼘㻌㻯㼑㼚㼠㼞㼑㻤ᯇᮏ䚷᫂ᏹ䚸㻿㻭㻾㻯㻭㻭㻺㻭㻹㻭㻾㻵㻭䚷㻰㻭㻺㻵㻱㻸㻭䚸㻾㼡㼕㼦㻌㻾㼛㼐㼞㼕㼓㼡㼑㼦㻌㻾㼍㼚㼐㼛㼘㼜㼔㻿㼍㼗㼕䚸㼆㻱㻵㻰㻭㻺㻌㻴㼍㼘㼍㻞㻜㻝㻣㻛㻣㻛㻤

㻞㻜㻝㻣㻛㻣㻛㻥 㛗㔝┴㻌ୖ⏣ᕷಙᕞ኱Ꮫୖ⏣䜻䝱䞁䝟䝇

➨㻡ᅇ඲ᅜ༤ኈㄢ⛬ᩍ⫱䝸䞊䝕䜱䞁䜾䝥䝻䜾䝷䝮Ꮫ⏕఍㆟䛻ཧຍ䛧䚸䝸䞊䝕䜱䞁䜾䝥䝻䜾䝷䝮䛻㛵䛩䜛᝟ሗ཰㞟䞉䝕䜱䝇䜹䝑䝅䝵䞁䜢⾜䛖䚹

㻥

⠛⏣䚷᪸ᶞ

㻞㻜㻝㻣㻛㻣㻛㻝㻤㻞㻜㻝㻣㻛㻣㻛㻞㻝 ᐩᒣ┴㻌ᐩᒣᕷᐩᒣᅜ㝿఍㆟ሙ኱ᡭ⏫䝣䜷䞊䝷䝮

➨㻝㻥ᅇ᪥ᮏ㻾㻺㻭Ꮫ఍ᖺ఍䛻ཧຍ䛧䚸䝸䞊䝕䜱䞁䜾䝥䝻䜾䝷䝮◊✲ㄢ㢟䛻㛵䛩䜛᝟ሗ཰㞟䛚䜘䜃䝫䝇䝍䞊Ⓨ⾲䜢⾜䛖䚹㻝㻜 ᑎ⏣䚷ఀ⧊㻞㻜㻝㻣㻛㻣㻛㻞㻣㻞㻜㻝㻣㻛㻣㻛㻞㻥 ᒱ㜧┴㻌ᒱ㜧ᕷ䛨䜕䛖䜝䛟䝥䝷䝄

➨㻟㻢ᅇ᪥ᮏ་⏝⏬ീᕤᏛ఍኱఍䜈ཧຍ䛧䚸䝸䞊䝕䜱䞁䜾䝥䝻䜾䝷䝮◊✲ㄢ㢟䛻㛵䛩䜛᝟ሗ཰㞟䜢⾜䛖䚹㻝㻝 ᯇᮏ䚷᫂ᏹ㻞㻜㻝㻣㻛㻤㻛㻟㻜㻞㻜㻝㻣㻛㻝㻞㻛㻞 䜰䝯䝸䜹㻌䝢䝑䝒䝞䞊䜾 㼁㼚㼕㼢㼑㼞㼟㼕㼠㼥㻌㼛㼒㻌㻼㼕㼠㼠㼟㼎㼡㼞㼓㼔㻝㻞 㻸㻝ᒚಟ⏕㻞㻜㻝㻣㻛㻥㻛㻤

㻞㻜㻝㻣㻛㻥㻛㻤 ஂୡ㒆㻌ஂᚚᒣ⏫

䝣䜯䝹䝁䝞䜲䜸䝅䝇䝔䝮䝈 䝸䞊䝕䜱䞁䜾䝥䝻䜾䝷䝮Ꮫ㝿ᛂ⏝⛉┠䛂་⒪䞉⏕άᨭ᥼䝅䝇䝔䝮Ꮫ䛃䛻䛚䛡䜛⏬ീデ᩿ᶵჾ䞉᳨ᰝศᯒᶵჾ䛾⥲ྜ◊✲ᡤぢᏛᐇ⩦䜢⾜䛖䚹㻝㻟 㻸㻝ᒚಟ⏕㻞㻜㻝㻣㻛㻥㻛㻝㻞㻞㻜㻝㻣㻛㻥㻛㻝㻞 ி㒔ᕷᓥὠ〇సᡤ䠄ᮏ♫䞉୕᮲ᕤሙ䠅䝸䞊䝕䜱䞁䜾䝥䝻䜾䝷䝮Ꮫ㝿ᛂ⏝⛉┠䛂་⒪䞉⏕άᨭ᥼䝅䝇䝔䝮Ꮫ䛃䛻䛚䛡䜛་⏝⏬ീᶵჾ㛤Ⓨ⌧ሙ䛾ぢᏛᐇ⩦䜢⾜䛖䚹㻝㻠 ᑎ⏣䚷ఀ⧊㻞㻜㻝㻣㻛㻥㻛㻝㻞㻞㻜㻝㻣㻛㻥㻛㻝㻞 රᗜ┴㻌⚄ᡞᕷරᗜ┴❧኱Ꮫ

රᗜ┴❧኱Ꮫ኱Ꮫ䚷ᛂ⏝᝟ሗ⛉Ꮫ◊✲⛉䚷ཎཱྀ䚷ு䚷෸ᩍᤵ䛸䝸䞊䝕䜱䞁䜾䝥䝻䜾䝷䝮◊✲ㄢ㢟䛻㛵䛩䜛ពぢ஺᥮䜢⾜䛖䚹㻝㻡 ᑎ⏣䚷ఀ⧊㻞㻜㻝㻣㻛㻥㻛㻝㻠㻞㻜㻝㻣㻛㻥㻛㻝㻢 㛗㔝┴㻌ୖ⏣ᕷಙᕞ኱Ꮫୖ⏣䜻䝱䞁䝟䝇

⏕య་ᕤᏛ䝅䞁䝫䝆䜴䝮㻞㻜㻝㻣䜈ཧຍ䛧䚸䝸䞊䝕䜱䞁䜾䝥䝻䜾䝷䝮◊✲ㄢ㢟䛻㛵䛩䜛᝟ሗ཰㞟䜢⾜䛖䚹㻝㻢 㻿㼔㼍㼙㼕㼙㼍㻌㻿㼡㼘㼠㼍㼚㼍㻞㻜㻝㻣㻛㻥㻛㻝㻢㻞㻜㻝㻣㻛㻥㻛㻞㻝 ி㒔ᕷᅜ❧ி㒔ᅜ㝿఍㤋㼄㼄㻵㻵㻵㻌㼃㼛㼞㼘㼐㻌㻯㼛㼚㼓㼞㼑㼟㼟㻌㼛㼒㻌㻺㼑㼡㼞㼛㼘㼛㼓㼥䜈ཧຍ䛧䚸䝸䞊䝕䜱䞁䜾䝥䝻䜾䝷䝮◊✲ㄢ㢟䛻㛵䛩䜛᝟ሗ཰㞟䜢⾜䛖䚹㻝㻣 㻸㻝ᒚಟ⏕㻞㻜㻝㻣㻛㻥㻛㻝㻥㻞㻜㻝㻣㻛㻥㻛㻝㻥 ி㒔ᕷ㧗㱋⪅⚟♴᪋タᮏ⬟䝸䞊䝕䜱䞁䜾䝥䝻䜾䝷䝮Ꮫ㝿ᛂ⏝⛉┠䛂་⒪䞉⏕άᨭ᥼䝅䝇䝔䝮Ꮫ䛃䛻䛚䛡䜛ᆅᇦໟᣓᨭ᥼䝉䞁䝍䞊䛾ぢᏛᐇ⩦䜢⾜䛖䚹㻝㻤 㻸㻝ᒚಟ⏕㻞㻜㻝㻣㻛㻥㻛㻞㻢㻞㻜㻝㻣㻛㻥㻛㻞㻢 ዉⰋ┴㻌ዉⰋᕷ㧗䛾ཎ䝫䝅䝤䝹䝕䜲䜿䜰䝉䞁䝍䞊䝸䞊䝕䜱䞁䜾䝥䝻䜾䝷䝮Ꮫ㝿ᛂ⏝⛉┠䛂་⒪䞉⏕άᨭ᥼䝅䝇䝔䝮Ꮫ䛃䛻䛚䛡䜛㐠ື≉໬ᆺ䝕䜲䜿䜰䛾ぢᏛᐇ⩦䜢⾜䛖䚹㻝㻥 㝞䚷ⲗ

㻞㻜㻝㻣㻛㻥㻛㻞㻣㻞㻜㻝㻣㻛㻥㻛㻟㻜 ⚄ዉᕝ┴㻌ᶓ὾ᕷ䝟䝅䝣䜱䝁ᶓ὾

➨㻣㻢ᅇ᪥ᮏ⒴Ꮫ఍Ꮫ⾡⥲఍䜈ཧຍ䛧䚸䝸䞊䝕䜱䞁䜾䝥䝻䜾䝷䝮◊✲ㄢ㢟䛻㛵䛩䜛᝟ሗ཰㞟䜢⾜䛖䚹㻞㻜 ๓⏣䚷ಙኴ㑻㻞㻜㻝㻣㻛㻥㻛㻞㻤㻞㻜㻝㻣㻛㻥㻛㻟㻜 ⚄ዉᕝ┴㻌ᶓ὾ᕷ䝟䝅䝣䜱䝁ᶓ὾

➨㻣㻢ᅇ᪥ᮏ⒴Ꮫ఍Ꮫ⾡㞟఍䜈ཧຍ䛧䚸䝸䞊䝕䜱䞁䜾䝥䝻䜾䝷䝮◊✲ㄢ㢟䛻㛵䛩䜛ཱྀ㢌Ⓨ⾲䛚䜘䜃᝟ሗ཰㞟䜢⾜䛖䚹㻞㻝 ㉥ᕝ䚷♩⨾㻞㻜㻝㻣㻛㻝㻜㻛㻥㻞㻜㻝㻣㻛㻝㻞㻛㻝㻡 䝗䜲䝒㻌䝪䞁㼁㼚㼕㼢㼑㼞㼟㼕㼠㼥㻌㼛㼒㻌㻮㼛㼚㼚䝪䞁኱Ꮫ䚷㻶㾇㼞㼓㼑㼚㻌㻮㼍㼖㼛㼞㼍㼠㼔ᩍᤵ䛾䜒䛸䚸䝸䞊䝕䜱䞁䜾䝥䝻䜾䝷䝮◊✲ㄢ㢟䛻㛵䛩䜛䜲䞁䝍䞊䞁䝅䝑䝥䜢⾜䛖䚹ᐑஅཎ䚷㑂䚸す㇂䚷ᬸᙪ䚸⛗㇂䚷㞙ୡ䚸㻿㻭㻾㻯㻭㻞㻞 㻭㻺㻭㻹㻭㻾㻵㻭䚷㻰㻭㻺㻵㻱㻸㻭䚸㻾㼡㼕㼦㻌㻾㼛㼐㼞㼕㼓㼡㼑㼦㻌㻾㼍㼚㼐㼛㼘㼜㼔㻿㼍㼗㼕䚸㻵㻿㻸㻭㻹㻌㻴㼑㼘㼑㼚㼍㻞㻜㻝㻣㻛㻝㻜㻛㻝㻥㻞㻜㻝㻣㻛㻝㻜㻛㻞㻝 ឡ▱┴㻌ྡྂᒇᕷྡྂᒇ䝬䝸䜸䝑䝖䜰䝋䝅䜰䝩䝔䝹䜋䛛༤ኈㄢ⛬ᩍ⫱䝸䞊䝕䜱䞁䜾䝥䝻䜾䝷䝮䝣䜷䞊䝷䝮㻞㻜㻝㻣䜈ཧຍ䛧䚸䝸䞊䝕䜱䞁䜾䝥䝻䜾䝷䝮䛻㛵䛩䜛ពぢ஺᥮䛚䜘䜃᝟ሗ཰㞟䜢⾜䛖䚹㻞㻟 ᮤ䚷㞷ị㻞㻜㻝㻣㻛㻝㻜㻛㻝㻥㻞㻜㻝㻣㻛㻝㻝㻛㻞㻜 䝗䜲䝒㻌䝪䞁㼁㼚㼕㼢㼑㼞㼟㼕㼠㼥㻌㼛㼒㻌㻮㼛㼚㼚䝪䞁኱Ꮫ䚷㻶㾇㼞㼓㼑㼚㻌㻮㼍㼖㼛㼞㼍㼠㼔ᩍᤵ䛾䜒䛸䚸䝸䞊䝕䜱䞁䜾䝥䝻䜾䝷䝮◊✲ㄢ㢟䛻㛵䛩䜛䜲䞁䝍䞊䞁䝅䝑䝥䜢⾜䛖䚹㻞㻠 ๓⏣䚷ಙኴ㑻㻞㻜㻝㻣㻛㻝㻜㻛㻞㻜㻞㻜㻝㻣㻛㻝㻜㻛㻞㻞 ᮾி㒔ᮾிᅜ㝿䝣䜷䞊䝷䝮➨㻣㻥ᅇ᪥ᮏ⾑ᾮᏛ఍Ꮫ⾡㞟఍䜈ཧຍ䛧䚸䝸䞊䝕䜱䞁䜾䝥䝻䜾䝷䝮◊✲ㄢ㢟䛻㛵䛩䜛ཱྀ㢌Ⓨ⾲䛚䜘䜃᝟ሗ཰㞟䜢⾜䛖䚹㻞㻡 ᑎ⏣䚷ఀ⧊㻞㻜㻝㻣㻛㻝㻜㻛㻞㻠㻞㻜㻝㻣㻛㻝㻜㻛㻞㻣 ᐑᇛ┴㻌ከ㈡ᇛᕷ

ከ㈡ᇛᕷᩥ໬䝉䞁䝍䞊➨㻟㻤ᅇ㉸㡢Ἴ䜶䝺䜽䝖䝻䝙䜽䝇䛾ᇶ♏䛸ᛂ⏝䛻㛵䛩䜛䝅䞁䝫䝆䜴䝮䛻ཧຍ䛧䚸䝸䞊䝕䜱䞁䜾䝥䝻䜾䝷䝮◊✲ㄢ㢟䛻㛵䛩䜛᝟ሗ཰㞟䜢⾜䛖䚹㻞㻢 ෆᮏ䚷㝧

㻞㻜㻝㻣㻛㻝㻜㻛㻞㻥㻞㻜㻝㻣㻛㻝㻝㻛㻞 ᮾி㒔⟃Ἴ኱Ꮫᮾி䜻䝱䞁䝟䝇ᩥிᰯ⯋᪥ᮏගᏛ఍ᖺḟᏛ⾡ㅮ₇఍䚷㻻㼜㼠㼕㼏㼟㻌㻒㻌㻼㼔㼛㼠㼛㼚㼕㼏㼟㻌㻶㼍㼜㼍㼚㻌㻞㻜㻝㻣䇷㻌㼀㼛㼗㼥㼛㻌䇷䜈ཧຍ䛧䝸䞊䝕䜱䞁䜾䝥䝻䜾䝷䝮◊✲ㄢ㢟䛻㛵䛩䜛᝟ሗ཰㞟䜢⾜䛖䚹㻞㻣 㻿㻭㻾㻯㻭䚷㻭㻺㻭㻹㻭㻾㻵㻭䚷㻰㻭㻺㻵㻱㻞㻜㻝㻣㻛㻝㻝㻛㻝㻞㻜㻝㻣㻛㻝㻝㻛㻟 ᚨᓥ┴㻌ᚨᓥ┴ᚨᓥ኱Ꮫ་ṑ⸆Ꮫ◊✲㒊ᚨᓥ኱Ꮫ䚷་ṑ⸆Ꮫ◊✲㒊䚷ᇼᕝ୍ᶞ䚷ᩍᤵ䜢ゼၥ䛧䚸䝸䞊䝕䜱䞁䜾䝥䝻䜾䝷䝮◊✲ㄢ㢟䛻㛵䛩䜛ᐇ㦂䜢⾜䛖䚹㻞㻤 㻿㼔㼍㼙㼕㼙㼍㻌㻿㼡㼘㼠㼍㼚㼍㻞㻜㻝㻣㻛㻝㻝㻛㻟㻞㻜㻝㻣㻛㻝㻝㻛㻡 ி㒔ᕷᅜ❧ி㒔ᅜ㝿఍㤋➨㻡㻝ᅇ᪥ᮏ䛶䜣䛛䜣Ꮫ఍Ꮫ⾡㞟఍䜈ཧຍ䛧䚸䝸䞊䝕䜱䞁䜾䝥䝻䜾䝷䝮◊✲ㄢ㢟䛻㛵䛩䜛᝟ሗ཰㞟䜢⾜䛖䚹㻴㼍㼚㼟㻌㻷㼚㾁㼘㼘㻌㻵㼚㼟㼠㼕㼠㼡㼠㼑䚷㻶㼍㼚㻌㻷㾁㼟㼘㼕㼚㼓㻙㼃㼑㼠㼠㼟㼠㼍㼑㼐㼠Ặ䛾䜒䛸䚸䝸䞊䝕䜱䞁䜾䝥䝻䜾䝷䝮◊✲ㄢ㢟䛻㛵䛩䜛䜲䞁䝍䞊䞁䝅䝑䝥䛚䜘䜃㼄㼂㻌㻱㼡㼞㼛㼜㼑㼍㼚㻌㻮㼕㼛㼘㼛㼓㼕㼏㼍㼘㻌㻾㼔㼥㼠㼔㼙㼟㻌㻿㼛㼏㼕㼑㼠㼥㻌㻯㼛㼚㼓㼞㼑㼟㼟䛻ཧຍ䛧䚸䝸䞊䝕䜱䞁䜾䝥䝻䜾䝷䝮◊✲ㄢ㢟䛻㛵䛩䜛᝟ሗ཰㞟䜢⾜䛖䚹䝢䝑䝒䝞䞊䜾኱Ꮫ䚷㼀㼔㼑㼞㼑㼟㼍㻌㻸㻚㻌㼃㼔㼕㼠㼑㼟㼕㼐㼑ᩍᤵ䛾䜒䛸䚸䝸䞊䝕䜱䞁䜾䝥䝻䜾䝷䝮◊✲ㄢ㢟䛻㛵䛩䜛䜲䞁䝍䞊䞁䝅䝑䝥䜢⾜䛖䚹㻞㻜㻝㻣㻛㻝㻝㻛㻞㻡 䜰䝯䝸䜹㻌䝠䝳䞊䝇䝖䞁㼀㼔㼑㻌㼁㼚㼕㼢㼑㼞㼟㼕㼠㼥㻌㼛㼒㻌㼀㼑㼤㼍㼟㻙㻴㼛㼡㼟㼠㼛㼚㻌㻹㼑㼐㼕㼏㼍㼘㻌㻿㼏㼔㼛㼛㼘䝔䜻䝃䝇኱Ꮫ䚷㼃㼕㼘㼘㼕㼍㼙㻌㻰㼛㼣㼔㼍㼚ᩍᤵ䛾䜒䛸䚸䝸䞊䝕䜱䞁䜾䝥䝻䜾䝷䝮◊✲ㄢ㢟䛻㛵䛩䜛䜲䞁䝍䞊䞁䝅䝑䝥䜢⾜䛖䚹㻟㻜 㻿㻭㻾㻯㻭䚷㻭㻺㻭㻹㻭㻾㻵㻭䚷㻰㻭㻺㻵㻱 㻞㻜㻝㻣㻛㻝㻝㻛㻞㻠㻞㻜㻝㻣㻛㻝㻝㻛㻞㻢 ᮾி㒔୰㔝䝃䞁䝥䝷䝄

➨㻟㻝ᅇ᪥ᮏ䜶䜲䝈Ꮫ఍Ꮫ⾡㞟఍䞉⥲఍䜈ཧຍ䛧䚸䝸䞊䝕䜱䞁䜾䝥䝻䜾䝷䝮◊✲ㄢ㢟䛻㛵䛩䜛䝫䝇䝍䞊䝥䝺䝊䞁䝔䞊䝅䝵䞁䛚䜘䜃᝟ሗ཰㞟䜢⾜䛖䚹㻟㻝 ΎỈ䚷┤Ⓩ

㻞㻜㻝㻣㻛㻝㻝㻛㻞㻣㻞㻜㻝㻣㻛㻝㻝㻛㻞㻥 ᒱ㜧┴㻌ᒱ㜧ᕷ㛗Ⰻᕝᅜ㝿఍㆟ሙ䜋䛛➨㻞㻠ᅇ㻰㻺㻭」〇䞉⤌᥮䛘䞉ಟ᚟䝽䞊䜽䝅䝵䝑䝥䜈ཧຍ䛧䝸䞊䝕䜱䞁䜾䝥䝻䜾䝷䝮◊✲ㄢ㢟䛻㛵䛩䜛᝟ሗ཰㞟䜢⾜䛖䚹㻟㻞 㻿㼔㼍㼙㼕㼙㼍㻌㻿㼡㼘㼠㼍㼚㼍㻞㻜㻝㻣㻛㻝㻝㻛㻟㻜㻞㻜㻝㻣㻛㻝㻞㻛㻣 䜰䝯䝸䜹㻌䝽䝅䞁䝖䞁㻰㻯㼃㼍㼘㼠㼑㼞㻌㻱㻚㻌㼃㼍㼟㼔㼕㼚㼓㼠㼛㼚㻯㼛㼚㼢㼑㼚㼠㼕㼛㼚㻌㻯㼑㼚㼠㼑㼞㻭㼙㼑㼞㼕㼏㼍㼚㻌㻱㼜㼕㼘㼑㼜㼟㼥㻌㻿㼛㼏㼕㼑㼠㼥㻌㻭㼚㼚㼡㼍㼘㻌㻹㼑㼑㼠㼕㼚㼓㻌㻞㻜㻝㻣䜈ཧຍ䛧䚸䝸䞊䝕䜱䞁䜾䝥䝻䜾䝷䝮◊✲ㄢ㢟䛻㛵䛩䜛᝟ሗ཰㞟䜢⾜䛖䚹㻟㻟 ⠛⏣䚷᪸ᶞ㻞㻜㻝㻣㻛㻝㻞㻛㻢㻞㻜㻝㻣㻛㻝㻞㻛㻥 රᗜ┴㻌⚄ᡞᕷ⚄ᡞ䝫䞊䝖䜰䜲䝷䞁䝗㻞㻜㻝㻣ᖺᗘ䚷⏕࿨⛉Ꮫ⣔Ꮫ఍ྜྠᖺḟ኱఍䛻ཧຍ䛧䚸䝸䞊䝕䜱䞁䜾䝥䝻䜾䝷䝮◊✲ㄢ㢟䛻㛵䛩䜛᝟ሗ཰㞟䞉䝫
䝇䝍䞊Ⓨ⾲䜢⾜䛖䚹㻟㻠 㻵㻿㻸㻭㻹㻌㻴㼑㼘㼑㼚㼍㻞㻜㻝㻣㻛㻝㻞㻛㻢㻞㻜㻝㻣㻛㻝㻞㻛㻥 රᗜ┴㻌⚄ᡞᕷ⚄ᡞ䝫䞊䝖䜰䜲䝷䞁䝗㻞㻜㻝㻣ᖺᗘ䚷⏕࿨⛉Ꮫ⣔Ꮫ఍ྜྠᖺḟ኱఍䛻ཧຍ䛧䚸䝸䞊䝕䜱䞁䜾䝥䝻䜾䝷䝮◊✲ㄢ㢟䛻㛵䛩䜛᝟ሗ཰㞟䜢⾜䛖䚹㻟㻡 ᇽୖ䚷ஂ⨾Ꮚ㻞㻜㻝㻣㻛㻝㻞㻛㻢㻞㻜㻝㻣㻛㻝㻞㻛㻤 රᗜ┴㻌⚄ᡞᕷ⚄ᡞ䝫䞊䝖䜰䜲䝷䞁䝗㻞㻜㻝㻣ᖺᗘ䚷⏕࿨⛉Ꮫ⣔Ꮫ఍ྜྠᖺḟ኱఍䛻ཧຍ䛧䚸䝸䞊䝕䜱䞁䜾䝥䝻䜾䝷䝮◊✲ㄢ㢟䛻㛵䛩䜛᝟ሗ཰㞟䜢⾜䛖䚹㻟㻢 ๓ᕝ䚷ὒኴ㻞㻜㻝㻣㻛㻝㻞㻛㻢㻞㻜㻝㻣㻛㻝㻞㻛㻥 රᗜ┴㻌⚄ᡞᕷ⚄ᡞ䝫䞊䝖䜰䜲䝷䞁䝗㻞㻜㻝㻣ᖺᗘ䚷⏕࿨⛉Ꮫ⣔Ꮫ఍ྜྠᖺḟ኱఍䛻ཧຍ䛧䚸䝫䝇䝍䞊Ⓨ⾲䛚䜘䜃䝸䞊䝕䜱䞁䜾䝥䝻䜾䝷䝮◊✲ㄢ㢟䛻㛵䛩䜛᝟ሗ཰㞟䜢⾜䛖䚹㻟㻣 ஭䝜ୖ䚷㞝୍㻞㻜㻝㻣㻛㻝㻞㻛㻢㻞㻜㻝㻣㻛㻝㻞㻛㻥 රᗜ┴㻌⚄ᡞᕷ⚄ᡞ䝫䞊䝖䜰䜲䝷䞁䝗㻞㻜㻝㻣ᖺᗘ䚷⏕࿨⛉Ꮫ⣔Ꮫ఍ྜྠᖺḟ኱఍䛻ཧຍ䛧䚸䝫䝇䝍䞊Ⓨ⾲䛚䜘䜃䝸䞊䝕䜱䞁䜾䝥䝻䜾䝷䝮◊✲ㄢ㢟䛻㛵䛩䜛᝟ሗ཰㞟䜢⾜䛖䚹㻟㻤 ᑠᓥ䚷Ⳁᯝ㻞㻜㻝㻣㻛㻝㻞㻛㻣㻞㻜㻝㻣㻛㻝㻞㻛㻣 රᗜ┴㻌⚄ᡞᕷ⚄ᡞ䝫䞊䝖䜰䜲䝷䞁䝗㻞㻜㻝㻣ᖺᗘ䚷⏕࿨⛉Ꮫ⣔Ꮫ఍ྜྠᖺḟ኱఍䛻ཧຍ䛧䚸䝸䞊䝕䜱䞁䜾䝥䝻䜾䝷䝮◊✲ㄢ㢟䛻㛵䛩䜛᝟ሗ཰㞟䜢⾜䛖䚹㻟㻥 ⛗㇂䚷㞙ୡ㻞㻜㻝㻣㻛㻝㻞㻛㻝㻡㻞㻜㻝㻣㻛㻝㻞㻛㻝㻡 ᮾி㒔ᮾிᕤᴗ኱Ꮫ
኱ᒸᒣ䜻䝱䞁䝟䝇

➨㻠ᅇ㻵㼀๰⸆䝁䞁䝔䝇䝖Ⓨ⾲఍䞉⾲ᙲᘧ䛻ཧຍ䛧䚸䝸䞊䝕䜱䞁䜾䝥䝻䜾䝷䝮◊✲ㄢ㢟䛻㛵䛩䜛᝟ሗ཰㞟䜢⾜䛖䚹㻠㻜 ᯇᮏ䚷᫂ᏹ㻞㻜㻝㻣㻛㻝㻞㻛㻝㻥㻞㻜㻝㻣㻛㻝㻞㻛㻞㻡 䝍䜲㻌䝏䜵䞁䝷䜲㻹㼍㼑㻌㻲㼍㼔㻌㻸㼡㼍㼚㼓㻌㼁㼚㼕㼢㼑㼞㼟㼕㼠㼥㻹㼍㼑㻌㻲㼍㼔㻌㻸㼡㼍㼚㼓㻌㼁㼚㼕㼢㼑㼞㼟㼕㼠㼥㻌㻿㼏㼔㼛㼛㼘㻌㼛㼒㻌㻹㼑㼐㼕㼏㼕㼚㼑䜢ゼၥ䛧䚸㻠㼠㼔㻌㻭㼚㼚㼡㼍㼘㻌㻿㼏㼕㼑㼚㼠㼕㼒㼕㼏㻌㻯㼛㼚㼒㼑㼞㼑㼚㼏㼑㻌㼕㼚㻌㻯㼔㼕㼍㼚㼓㻌㻾㼍㼕䛻䛶䝸䞊䝕䜱䞁䜾䝥䝻䜾䝷䝮◊✲ㄢ㢟䛻㛵䛩䜛Ⓨ⾲䜢⾜䛖䚹㻠㻝 す㇂䚷ᬸᙪ㻞㻜㻝㻤㻛㻝㻛㻥

㻞㻜㻝㻤㻛㻝㻛㻝㻜 ᮾி㒔ᮾி኱Ꮫఀ⸨ᅜ㝿Ꮫ⾡◊✲䝉䞁䝍䞊㻯㻱㻹㻿㼡㼜㼞㼍㻌㻞㻜㻝㻤䜈ฟᖍ䛧䚸䝸䞊䝕䜱䞁䜾䝥䝻䜾䝷䝮◊✲ㄢ㢟䛻㛵䛩䜛䝫䝇䝍䞊Ⓨ⾲䛚䜘䜃᝟ሗ཰㞟䜢⾜䛖䚹㻠㻞 㼆㻱㻵㻰㻭㻺㻌㻴㼍㼘㼍㻞㻜㻝㻤㻛㻝㻛㻝㻢㻞㻜㻝㻤㻛㻝㻛㻝㻢 ឡ▱┴㻌኱ᗓᕷᅜ❧㛗ᑑ་⒪◊✲䝉䞁䝍䞊ᅜ❧㛗ᑑ་⒪◊✲䝉䞁䝍䞊䚷⪁ᖺᏛ䞉♫఍⛉Ꮫ◊✲䝉䞁䝍䞊䚷Ⲩ஭⚽඾䝉䞁䝍䞊㛗䜢ゼၥ䛧䚸䝸䞊䝕䜱䞁䜾䝥䝻䜾䝷䝮䜲䞁䝍䞊䞁䝅䝑䝥䛻㛵䛩䜛஦๓ᡴྜ䛫䜢⾜䛖䚹㻠㻟 すᒣ䚷⨾ဏ㻞㻜㻝㻤㻛㻝㻛㻞㻤㻞㻜㻝㻤㻛㻝㻛㻟㻝 䜰䝯䝸䜹㻌䝃䞁䝣䝷䞁䝅䝇㻹㼛㼟㼏㼛㼚㼑㻌㻯㼑㼚㼠㼑㼞㻿㻼㻵㻱㻌㻼㼔㼛㼠㼛㼚㼕㼏㼟㻌㼃㼑㼟㼠㻌㻞㻜㻝㻤䜈ཧຍ䛧䚸䝸䞊䝕䜱䞁䜾䝥䝻䜾䝷䝮◊✲ㄢ㢟䛻㛵䛩䜛᝟ሗ཰㞟䜢⾜䛖䚹㻠㻠 㻹㼍㼔㼙㼡㼐㻌㻹㼐㻌㻾㼍㼟㼑㼘㻌㻭㼘㻞㻜㻝㻤㻛㻝㻛㻟㻜㻞㻜㻝㻤㻛㻞㻛㻞㻢 䝇䝨䜲䞁㻌䝉䝡䝸䜰㻯㻭㻮㻵㻹㻱㻾

㻭㼚㼐㼍㼘㼡㼟㼕㼍㼚㻌㻯㼑㼚㼠㼑㼞㻌㼒㼛㼞㻌㻹㼛㼘㼑㼏㼡㼘㼍㼞㻌㻮㼕㼛㼘㼛㼓㼥㼍㼚㼐㻌㻾㼑㼓㼑㼚㼑㼞㼍㼠㼕㼢㼑㻌㻹㼑㼐㼕㼏㼕㼚㼑㻌㻔㻯㻭㻮㻵㻹㻱㻾㻕㻘㻿㼜㼍㼕㼚㻌㻰㼞㻚㻌㻲㼑㼘㼕㼜㼑㻌㻯㼛㼞㼠㽴㼟㻸㼑㼐㼑㼟㼙㼍䛾䜒䛸䚸䝸䞊䝕䜱䞁䜾䝥䝻䜾䝷䝮◊✲ㄢ㢟䛻㛵䛩䜛䜲䞁䝍䞊䞁䝅䝑䝥䜢ᐇ᪋䛩䜛䚹㻠㻡 㼆㻱㻵㻰㻭㻺㻌㻴㼍㼘㼍㻞㻜㻝㻤㻛㻞㻛㻟

㻞㻜㻝㻤㻛㻞㻛㻠 ୕㔜┴㻌ὠᕷ୕㔜┴⥲ྜᩥ໬䝉䞁䝍䞊᪥ᮏᅾᏯ་Ꮫ఍䚷➨㻟ᅇᆅᇦ䝣䜷䞊䝷䝮㻌㼕㼚㻌୕㔜䛻ཧຍ䛧䚸䝸䞊䝕䜱䞁䜾䝥䝻䜾䝷䝮◊✲ㄢ㢟䛻㛵䛩䜛᝟ሗ཰㞟䜢⾜䛖䚹㻠㻢 㼆㻱㻵㻰㻭㻺㻌㻴㼍㼘㼍㻞㻜㻝㻤㻛㻞㻛㻥

㻞㻜㻝㻤㻛㻞㻛㻝㻝 ⚟ᒸ┴㻌⚟ᒸᕷ⚟ᒸᅜ㝿఍㆟ሙ➨㻝㻢ᅇ᪥ᮏ䝣䝑䝖䜿䜰Ꮫ఍ᖺḟᏛ⾡㞟఍䛻ཧຍ䛧䚸䝸䞊䝕䜱䞁䜾䝥䝻䜾䝷䝮◊✲ㄢ㢟䛻㛵䛩䜛᝟ሗ཰㞟䜢⾜䛖䚹㻠㻣 㻸㻵㼀㻻㻺㻌㻷㼁㻹㻭㻾㻌㻿㻭㻴㻭㻞㻜㻝㻤㻛㻞㻛㻝㻜㻞㻜㻝㻤㻛㻞㻛㻝㻣 䝯䜻䝅䝁㻌䜹䞁䜽䞁㻲㼕㼑㼟㼠㼍㻌㻭㼙㼑㼞㼕㼏㼍㼚㼍㻌㻯㼛㼚㼐㼑㼟㼍㻲㼁㻿㻵㻻㻺㻌㻟㼞㼐㻌㻰㻺㻭㻌㻾㼑㼜㼘㼕㼏㼍㼠㼕㼛㼚㻛㻾㼑㼜㼍㼕㼞㻌㻿㼠㼞㼡㼏㼠㼡㼞㼑㼟㻌㼍㼚㼐㻌㻯㼍㼚㼏㼑㼞㻌㻯㼛㼚㼒㼑㼞㼑㼚㼏㼑䜈ཧຍ䛧䚸䝸䞊䝕䜱䞁䜾䝥䝻䜾䝷䝮◊✲ㄢ㢟䛻㛵䛩䜛᝟ሗ཰㞟䜢⾜䛖䚹㻠㻤 㼆㻱㻵㻰㻭㻺㻌㻴㼍㼘㼍㻞㻜㻝㻤㻛㻞㻛㻝㻟㻞㻜㻝㻤㻛㻟㻛㻟㻜 ឡ▱┴㻌኱ᗓᕷᅜ❧㛗ᑑ་⒪◊✲䝉䞁䝍䞊ᅜ❧㛗ᑑ་⒪◊✲䝉䞁䝍䞊䚷⪁ᖺᏛ䞉♫఍⛉Ꮫ◊✲䝉䞁䝍䞊䚷Ⲩ஭⚽඾䝉䞁䝍䞊㛗䛾䜒䛸䚸䝸䞊䝕䜱䞁䜾䝥䝻䜾䝷䝮䜲䞁䝍䞊䞁䝅䝑䝥䜢⾜䛖䚹㻠㻥 ᑠᓥ䚷Ⳁᯝ㻞㻜㻝㻤㻛㻞㻛㻝㻣㻞㻜㻝㻤㻛㻠㻛㻤 䜲䜼䝸䝇㻌䝬䞁䝏䜵䝇䝍䞊㼁㼚㼕㼢㼑㼞㼟㼕㼠㼥㻌㼛㼒㻌㻹㼍㼚㼏㼔㼑㼟㼠㼑㼞䝬䞁䝏䜵䝇䝍䞊኱Ꮫ䚷㻭㼚㼐㼞㼑㼣㻌㻸㼛㼡㼐㼛㼚ᩍᤵ䛾䜒䛸䚸䝸䞊䝕䜱䞁䜾䝥䝻䜾䝷䝮◊✲ㄢ㢟䛻㛵䛩䜛䜲䞁䝍䞊䞁䝅䝑䝥䜢⾜䛖䚹㻡㻜 ๓⏣䚷ಙኴ㑻㻞㻜㻝㻤㻛㻟㻛㻝

㻞㻜㻝㻤㻛㻟㻛㻞㻡 䜰䝯䝸䜹㻌䝧䝉䝇䝎㻺㼍㼠㼕㼛㼚㼍㼘㻌㻴㼡㼙㼍㼚㻌㻳㼑㼚㼛㼙㼑㻌㼞㼑㼟㼑㼍㼞㼏㼔㻌㼕㼚㼟㼠㼕㼠㼡㼠㼑㻌㻔㻺㻴㻳㻾㻵㻕䚷㻌㻼㼍㼡㼘㻌㻼㻚㻌㻸㼕㼡Ặ䛾䜒䛸䚸䝸䞊䝕䜱䞁䜾䝥䝻䜾䝷䝮◊✲ㄢ㢟䛻㛵䛩䜛䜲䞁䝍䞊䞁䝅䝑䝥䜢ᐇ᪋䛩䜛䚹㻡㻝 㻿㻭㻾㻯㻭䚷㻭㻺㻭㻹㻭㻾㻵㻭䚷㻰㻭㻺㻵㻱㻞㻜㻝㻤㻛㻟㻛㻞

㻮㼛㼟㼠㼛㼚㻘㻌㻹㼍㼟㼟㼍㼏㼔㼡㼟㼑㼠㼠㼟䜰䝯䝸䜹㻴㼥㼚㼑㼟㻌㻯㼛㼚㼢㼑㼚㼠㼕㼛㼚㻞㻜㻝㻤㻛㻟㻛㻝㻟 䝪䝇䝖䞁䚸䝣䜱䝷䝕䝹㻯㼑㼚㼠㼑㼞㻘㼁㼚㼕㼢㼑㼞㼟㼕㼠㼥㻌㼛㼒㻌㼠㼔㼑䝣䜱䜰㻿㼏㼕㼑㼚㼏㼑㼟㻌㼕㼚㻌㻼㼔㼕㼘㼍㼐㼑㼘㼜㼔㼕㼍㻯㻾㻻㻵䜈ཧຍ䛧䚸䝫䝇䝍䞊Ⓨ⾲䛚䜘䜃䝸䞊䝕䜱䞁䜾䝥䝻䜾䝷䝮◊✲ㄢ㢟䛻㛵䛩䜛᝟ሗ཰㞟䚸䛚䜘䜃䝣䜱䝷䝕䝹䝣䜱䜰኱Ꮫ䛾䝉䝭䝘䞊䛻ཧຍ䛧䚸䝸䞊䝕䜱䞁䜾䝥䝻䜾䝷䝮◊✲ㄢ㢟䛻㛵䛩䜛᝟ሗ཰㞟䜢⾜䛖䚹㻡㻞 ㉥ᕝ䚷♩⨾䚸㻺㼍㼖㼚㼕㼚㻌㻾㼕㼒㼍㼠㻌㻭㼞㼍㻞㻜㻝㻤㻛㻟㻛㻝㻞㻞㻜㻝㻤㻛㻟㻛㻝㻡 ⚄ዉᕝ┴㻌ᶓ὾ᕷ䝟䝅䝣䜱䝁ᶓ὾

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<X.,085$3URJUDP6SHFLILF$VVRFLDWH3URIHVVRU/,06
LIMS program obligates domestic or abroad internship for students in order to expand
their mind outside the academic research field, to have an experience of work in the field ofindustry/public institution and to learn special technique/knowledge valuable for their LIMS
researches. To find the internship partner, we are encouraging students to take advantage of
IDM (Innovative Human Resource Development Matching) system, which is medium- andlong-term research internship matching system conducted by the consortium called IndustryAcademia

Collaborative

Collaborative

Education

Innovation
for

Human

Development

Association(C-ENGINE:

Next-Generation

INovators & Exploration of knowledge intersections;⏘Ꮫ༠ാ࢖ࣀ࣮࣋ࢩࣙࣥேᮦ⫱ᡂ༠㆟఍).
By

Kyoto

University

and

C-ENGINE,

graduate school research workshop and internshipmatching meeting was held at 5th floor of International
Science Innovation Building on June 26th. Cooperating
15 companies were participated and introduced theirwork, research, and their internship programs/policies.
From LIMS, 3 teachers/staffs and 5 students wereparticipated

and

all

LIMS

students

madepresentations (including one oral and five poster
presentations) about their researches. After thecompanies’

introduction

andstudents’posterpresentation, students freely visited the company’sbooth of their interest. They listened to more detail
explanation and discussed about the company’s
research and internship. A direct conversation withcompanies’ research representatives must be fruitful
not only for their internship but also their career plan.
We expect LIMS students to take much opportunities
of industry-academia exchange like this and acquire
the non-academic cultures.

LIMS students (4 from the left) talking atcompany’s booth

,QVWUXFWLRQIRU/,06LQWHUQVKLSDQG
5HVHDUFK,QWHUQVKLS0DWFKLQJ6\VWHP ,'0V\VWHP ,QWHUQVKLSUHSRUW'HFHPEHU.\RWR8QLYHUVLW\
<X.,085$3URJUDP6SHFLILF$VVRFLDWH3URIHVVRU/,06As an extension of knowledge and skills in
specialized and related fields acquired during
the 1st and 2nd grades, each student serves
his/her internship in a domestic industrial or
public organization, also in a laboratory orcompany abroad. Students are expected to
improve their practical abilities of research anddevelopment(R&D),

judgment

andcommunication.
On Dec. 27, 2017, We had instruction
meetingfortheinternship,includingorientation of IDM system for L1 and L3
transfer students. At first, I introduced
objectives and outlines of LIMS internship, andtalked about wiki-based internship reports bysenior students (bottom screenshot).
Then, Mr. Yoshihiro Fujimori (person in
charge, C-ENGINE conference) performed motivative talk about positioning of internship on
graduate school. Then, Mr. Mutsumi Kyukawa (C-ENGINE conference) explained orientationof the usage and outlines for matching between companies and students on IDM system.

 Next, we performed presentation session of internship report as a part of LIMS home room.
Five students who completed internship in AY 2017 were presented their activity
accomplishment, process for actual traveling, and anecdotes in internship.
It would be a good opportunity for attended students to build a concrete image of internship.
We continuously support and make these opportunities to encourage internship consulting andplanning by students themselves.

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6W\OH PLQSUHVHQWDWLRQZLWKVOLGHVGLVFXVVLRQLQFOXGLQJSKRWRVDQGEHORZFRQWHQWV 1) Name and grade,
2) Place of internship, 3) Period,
4) Purpose
5) How did you contact with the host and select the internship
6) Your activity at the internship, 7) Two photos at least
8) What did you learn from the internship? Was it according to your plan?
9) How was contact and networking with colleagues and supervision?
10) Benefits, your satisfaction rating
11) Did you reform your consciousness and carrier path after internship?
12) Cons, Improvements required, anecdotes, etc
13) Achievements with regards to LIMS research, 14) Advice to students going to internship㻴㻞㻥䜲䞁䝍䞊䞁䝅䝑䝥ᐇ᪋≧ἣ◊✲⛉䞉ᑓᨷ䞉
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Ṋ⏣䚷ಇ୍䚷ᩍᤵ⸆Ꮫ㻸㻟 ་⸆๰ᡂ᝟ሗ⛉Ꮫ䠠㻝㻔㻸㻟㻕ᮤ䚷㞷ịᕤᏛ㻸㻡 ྜᡂ䞉⏕≀໬Ꮫ㻰㻟㻔㻸㻡㻕ᡤᅾᆅᐇ᪋ᮇ㛫䠄䈜⏝ົᮇ㛫䠅

䝭䝷䝜䠄䜲䝍䝸䜰䠅㻞㻜㻝㻣㻚㻟㻚㻝䡚㻡㻚㻞㻡䠄㻝㻞㐌䠅䝜䞊䝇䜹䝻䝷䜲䝘ᕞ䝎䝷䝮䠄䜰䝯䝸䜹䠅㻞㻜㻝㻣㻚㻟㻚㻢䡚㻡㻚㻡䠄㻤㐌䠅䜲䜶䝘䠄䝗䜲䝒䠅

㻞㻜㻝㻣㻚㻣㻚㻝䡚㻤㻚㻟㻝䠄㻤㐌䠅䈜㻣㻛㻟㻜䡚㻤㻛㻟䛿Ꮫ఍ཧຍ䝨䞁䝅䝹䝧䝙䜰ᕞ䝢䝑䝒䝞䞊䜾䠄⡿ᅜ䠅㻞㻜㻝㻣㻚㻥㻚㻝䡚㻝㻝㻚㻟㻜䠄㻝㻞㐌䠅㼁㼚㼕㼢㼑㼞㼟㼕㼠㼥㻌㼛㼒㻌㻮㼛㼚㼚㻘㻌㻮㼛㼚㼚㻙㻭㼍㼏㼔㼑㼚㻌㻵㼚㼠㼑㼞㼚㼍㼠㼕㼛㼚㼍㼘㻌㻯㼑㼚㼠㼑㼞㼒㼛㼞㻌㻵㼚㼒㼛㼞㼙㼍㼠㼕㼛㼚㻌㼀㼑㼏㼔㼚㼛㼘㼛㼓㼥㻌㻮㻙㻵㼀㻼㼞㼛㼒㻚㻌㻰㼞㻚㻶㼡㼞㼓㼑㼚㻌㻮㼍㼖㼛㼞㼍㼠㼔䝪䞁䠄䝗䜲䝒䠅

㻞㻜㻝㻣㻚㻝㻜㻚㻝㻜䡚㻝㻞㻚㻝㻟䠄㻥㐌䠅᥃㇂䚷⚽᫛䚷ᩍᤵ㼁㼚㼕㼢㼑㼞㼟㼕㼠㼥㻌㼛㼒㻌㻮㼛㼚㼚㻘㻌㻮㼛㼚㼚㻙㻭㼍㼏㼔㼑㼚㻌㻵㼚㼠㼑㼞㼚㼍㼠㼕㼛㼚㼍㼘㻌㻯㼑㼚㼠㼑㼞㼒㼛㼞㻌㻵㼚㼒㼛㼞㼙㼍㼠㼕㼛㼚㻌㼀㼑㼏㼔㼚㼛㼘㼛㼓㼥㻌㻮㻙㻵㼀㻼㼞㼛㼒㻚㻌㻰㼞㻚㻌㻶㼡㼞㼓㼑㼚㻌㻮㼍㼖㼛㼞㼍㼠㼔䝪䞁䠄䝗䜲䝒䠅

㻞㻜㻝㻣㻚㻝㻜㻚㻞㻜䡚㻝㻝㻚㻝㻤
䠄㻠㐌䠅

Ỉ⸨䚷ᣅே

ᱵ⏣䚷┿㒓䚷ᩍᤵ㻰㼑㼜㼍㼞㼠㼙㼑㼚㼠㻌㼛㼒㻌㻮㼕㼛㼏㼔㼑㼙㼕㼟㼠㼞㼥㻌㻒㻌㻹㼛㼘㼑㼏㼡㼘㼍㼞㻌㻮㼕㼛㼘㼛㼓㼥㻘㼁㼚㼕㼢㼑㼞㼟㼕㼠㼥㻌㼛㼒㻌㼀㼑㼤㼍㼟㻌㻹㼑㼐㼕㼏㼍㼘㻌㻿㼏㼔㼛㼛㼘㻌㼍㼠㻌㻴㼛㼡㼟㼠㼛㼚㻭㼟㼟㼛㼏㼕㼍㼠㼑㻌㻼㼞㼛㼒㼑㼟㼟㼛㼞㻘㻌㻹㼕㼗㼔㼍㼕㼘㻌㻮㼛㼓㼐㼍㼚㼛㼢㼃㼕㼘㼘㼕㼍㼙㻌㻰㼛㼣㼔㼍㼚㻌㻸㼍㼎䝠䝳䞊䝇䝖䞁
䠄䜰䝯䝸䜹䠅

㻞㻜㻝㻣㻚㻝㻝㻚㻢䡚㻝㻝㻚㻞㻟䠄㻞㐌䠅㻸㻝 䠠㻝㻔㻸䠍㻕㻠ᖺไ㻹㼍㼔㼙㼡㼐㻌㻹㼐㻾㼍㼟㼑㼘㻌㻭㼘

Ṋ⏣䚷ಇ୍䚷ᩍᤵ㻭㼚㼐㼍㼘㼡㼟㼕㼍㼚㻌㻯㼑㼚㼠㼑㼞㻌㼒㼛㼞㻌㻹㼛㼘㼑㼏㼡㼘㼍㼞㻌㻮㼕㼛㼘㼛㼓㼥㼍㼚㼐㻌㻾㼑㼓㼑㼚㼑㼞㼍㼠㼕㼢㼑㻹㼑㼐㼕㼏㼕㼚㼑㻌㻔㻯㻭㻮㻵㻹㻱㻾㻕㻘㻿㼜㼍㼕㼚㻰㼞㻚㻌㻲㼑㼘㼕㼜㼑㻌㻯㼛㼞㼠㽴㼟㻌㻸㼑㼐㼑㼟㼙㼍䝉䝡䝸䜰䠄䝇䝨䜲䞁䠅

㻞㻜㻝㻤㻚㻝㻚㻟㻜䡚㻞㻚㻞㻢䠄㻟㐌䠅⸆Ꮫ㻸㻞 ་⸆๰ᡂ᝟ሗ⛉Ꮫ㻹㻞㻔㻸㻞㻕ᑠᓥ䚷Ⳁᯝᒸᮧ䚷ᆒ䚷ᩍᤵ

㼁㼚㼕㼢㼑㼞㼟㼕㼠㼥㻌㼛㼒㻌㻹㼍㼚㼏㼔㼑㼟㼠㼑㼞䚷㻯㼑㼚㼠㼞㼑㻌㼒㼛㼞㻌㼠㼔㼑㻌㼔㼕㼟㼠㼛㼞㼥㻌㼛㼒㼟㼏㼕㼑㼚㼏㼑㻘㻌㼀㼑㼏㼔㼚㼛㼘㼛㼓㼥㻌㼍㼚㼐㻌㻹㼑㼐㼕㼏㼕㼚㼑䝬䞁䝏䜵䝇䝍䞊
䠄䜲䜼䝸䝇䠅

㻞㻜㻝㻤㻚㻞㻚㻝㻣䡚㻠㻚㻤䠄㻢㐌䠅་Ꮫ㻸㻟 ே㛫೺ᗣ⛉Ꮫ⣔㻰㻝䠄㻸㻟㻕

㼆㻱㻵㻰㻭㻺䚷㻴㼍㼘㼍ᆤᒣ䚷┤⏕䚷ᩍᤵᅜ❧㛗ᑑ་⒪◊✲䝉䞁䝍䞊⪁ᖺᏛ䞉♫఍⛉Ꮫ◊✲䝉䞁䝍䞊䝉䞁䝍䞊㛗䚷Ⲩ஭䚷⚽඾ឡ▱┴኱ᗓᕷ

㻞㻜㻝㻤㻚㻞㻚㻝㻟䡚㻟㻚㻟㻜䠄㻢㐌䠅་Ꮫ㻸㻞 ே㛫೺ᗣ⛉Ꮫ⣔㻹㻞䠄㻸㻞㻕

๓⏣䚷ಙኴ㑻

་Ꮫ䞉་Ꮫ㼀㼞㼍㼚㼟㼘㼍㼠㼕㼛㼚㼍㼘㻌㼍㼚㼐㻌㻲㼡㼚㼏㼠㼕㼛㼚㼍㼘㻌㻳㼑㼚㼛㼙㼕㼏㻌㻮㼞㼍㼚㼏㼔㻘㻺㼍㼠㼕㼛㼚㼍㼘ୖஂಖ䚷㟹ᙪ䚷෸ᩍᤵ 㻴㼡㼙㼍㼚㻌㻳㼑㼚㼛㼙㼑㻌㼞㼑㼟㼑㼍㼞㼏㼔㻌㼕㼚㼟㼠㼕㼠㼡㼠㼑㻌㻔㻺㻴㻳㻾㻵㻕㻿㼑㼚㼕㼛㼞㻵㼚㼢㼑㼟㼠㼕㼓㼍㼠㼛㼞㻌㻼㼍㼡㼘㻌㻼㻚㻌㻸㼕㼡㻘㻌㻹㻚㻰㻚㻘㻌㻼㼔㻚㻰㻚䝧䝉䝇䝎㻞㻜㻝㻤㻚㻟㻚㻞䡚㻟㻚㻞㻟㻔䜰䝯䝸䜹䞉䝯䝸䞊䝷䞁䝗ᕞ㻕 䠄㻟㐌䠅㻌ᖹᡂ䠎㻥 ᖺ䠑᭶䠍䠒᪥㻌ி㒔኱Ꮫ㻌 グ⪅䜽䝷䝤㻌 ᚚ୰㻌 㻌ி㒔኱Ꮫ /,06 䝥䝻䜾䝷䝮䛾䛭䛾ᚋ⸆๣ᖌ䛛䜙䛾་ᕤ㐃ᦠ䜈䛾ᮇᚅ㻌 䛂་⒪ᕤᏛ≉ูㅮ₇఍䛃䛾㛤ദ䛻䛴䛔䛶
$,䠋,R7 ᫬௦䛻ྥ䛡䛶㻌 䡚㻌 ி㒔኱Ꮫ་Ꮫ㒊㝃ᒓ⑓㝔䛾ྲྀ䜚⤌䜏䡚ி㒔኱Ꮫ䛷䛿䚸䇾᭱ඛ➃䛾་Ꮫ䛾ᩍ⫱䞉◊✲⎔ቃ䛻䚸ᕤᏛ䛾Ꮫ⏕䛜᪩䛟䛛䜙ゐ䜜䚸་⒪䛾᪂䛧䛔㡿ᇦ䜢㛤ᣅ䛩䜛ᚲ↛ᛶ䜢Ꮫ䜆䚹䇿㻌 䛸䛔䛖ᴫᛕ䛾ୗ䚸㒊ᒁ㛫䛾ᇉ᰿䜢㉺䛘䛯་ᕤ㐃ᦠ䛻䜘䜛䠑ᖺ୍㈏༤ኈㄢ⛬ᩍ⫱䝸䞊䝕䜱䞁䜾䝥䝻䜾䝷䝮䜢ᐇ᪋䛧䛶䛚䜚䜎䛩䚹ᮏ䝥䝻䜾䝷䝮䛿䚸ᕤᏛ䛾Ꮫ⏕䛻䚸་Ꮫ䛾ᇶ♏䛛䜙⮫ᗋ䚸䛥䜙䛻䛿௓ㆤ䛻⮳䜛ᩍ⫱䞉ᐇ⩦䜢ㄢ䛧䚸་Ꮫ㒊༞ᴗ⏕䛸ྠ➼䛾▱㆑䜢᭷䛩䜛ḟୡ௦䛾䛂⥲ྜ་⒪㛤Ⓨ䝸䞊䝎䞊䛃䛾⫱ᡂ䜢┠ᣦ䛧䛶䛚䜚䚸/,06䠄/HDGHUVIRU,QWHJUDWHG0HGLFDO6\VWHP䠅䝥
䝻䜾䝷䝮䛸䛧䛶䚸ᖹᡂ䠎䠐ᖺ䛻ᩥ㒊⛉Ꮫ┬䞉䠄⊂䠅᪥ᮏᏛ⾡᣺⯆఍䛂༤ኈㄢ⛬ᩍ⫱䝸䞊䝕䜱䞁䜾䝥䝻䜾䝷䝮䛃䛻᥇ᢥ䛥䜜䜎䛧䛯䚹
/,06 䝥䝻䜾䝷䝮䛷䛿䚸᫖ᖺ䠍䠍᭶䠏䠌᪥䠄Ỉ䠅䛻䚸䛜䜣ᝈ⪅఍䞉132 ἲேᨭ䛘䛒䛖఍䛂Į䛃䛾๪⌮஦㛗 㔝⏣ ┿⏤⨾ Ặ䜢䛚ᣍ䛝䛧䚸/,06 䝥䝻䜾䝷䝮ᒚಟ⏕䜢ᑐ㇟䛸䛧䛯➨䠍ᅇ䛂་⒪ᕤᏛ≉ูㅮ₇఍䛃䜢㛤ദ⮴䛧䜎䛧䛯䚹㔝⏣Ặ䛿䚸/,06 እ㒊ホ౯ጤဨ఍ጤဨ䛾୍ே䛷䜒䛒䜚䚸ᝈ⪅┠⥺䛷 /,06 䝥䝻䜾䝷䝮䜢ホ౯㡬䛟䛸䛸䜒䛻䚸ᮏㅮ₇䛻䛚䛔䛶䚸ᝈ⪅䛸䛧䛶䛾ⱞປ䜔ᮇᚅ䜢ఏ䛘䛶㡬䛝䚸/,06 䝥䝻䜾䝷䝮ᒚಟ⏕䛻኱䛝䛺┠ⓗព㆑䜢ᢪ䛛䛫䜛䛣䛸䛜䛷䛝䜎䛧䛯䚹䛭䛣䛷䚸᮶䜛䠑᭶䠏䠌᪥䠄ⅆ䠅䛻䚸➨䠎ᅇ䛂་⒪ᕤᏛ≉ูㅮ₇఍䛃䜢㛤ദ⮴䛧䜎䛩䚹ㅮᖌ䛸䛧䛶䛿䚸⸆๣ᖌ⏺䛻⢭㏻䛧䛯ᖇிᖹᡂ኱Ꮫ⸆Ꮫ㒊䞉ᩍᤵ ஭ᡭཱྀ  ┤Ꮚ  ඛ⏕䜢䛚ᣍ䛝䛧䚸⸆๣ᖌ䛾ᙺ๭䛸
/,06 䝥䝻䜾䝷䝮ᒚಟ⏕䜈䛾ᮇᚅ䛻䛴䛔䛶䚸䛤ㅮ₇䛸 /,06 䝥䝻䜾䝷䝮ᒚಟ⏕䛻ᑐ䛩䜛ㄢ㢟ゎỴᆺ䛾䜾䝹䞊䝥䝽䞊䜽䛾ᐇ᪋䜢䛚㢪䛔䛧䛶䛚䜚䜎䛩䚹⸆䛾ᑓ㛛ᐙ䛸䛧䛶䛾⸆๣ᖌ䛾⫋ົ䛿䚸㏆ᖺ䛾ᅾᏯ་⒪䜈䛾䝅䝣䝖䛸䛸䜒䛻䚸㉁䞉㔞䛸䜒㧗䛟䛺䛳䛶䛔䜎䛩䛜䚸䛣䜜䜎䛷ᕤᏛ⣔䛾Ꮫ⏕䛜䛭䛾ᐇ᝟䜢▱䜛ᶵ఍䛿䛒䜚䜎䛫䜣䛷䛧䛯䚹஭ᡭཱྀඛ⏕䛾䛤ㅮ₇䜢㏻䛧䛶䚸⸆๣ᖌ䛾♫఍ⓗᙺ๭䛸㈐௵䜢Ꮫ䜃䛂ᕤᏛ⣔䛾ᑓ㛛ᛶ䜢ά䛛䛧䚸⸆๣ᖌ䛾⫋ົ䛻䛹䛾ᵝ䛺㈉⊩䛜䛷䛝䜛䛛䠛䛃䛻䛴䛔䛶䚸/,06 䝥䝻䜾䝷䝮ᒚಟ⏕䛜⪃䛘䜛ዎᶵ䛻䛺䜜䜀䛸ᛮ䛔䜎䛩䚹ሗ㐨㛵ಀ䛾ⓙᵝ䛻䛿䚸䛭䛾ᵝᏊ䜢ྲྀᮦ㡬䛡䜜䜀ᖾ䛔䛷䛩䚹䜎䛯䚸ㅮ₇఍䛻ඛ❧䛱䚸ู⣬䛾䛸䛚䜚グ⪅఍ぢ䜢㛤ദ䛩䜛ᡤᏑ䛷䛩䛾䛷䚸ሗ㐨㛵ಀ䛾ⓙᵝ䛻䛿䚸୓㇟䛚⧞䜚ྜ䜟䛫䛾ୖ䚸䛤ฟᖍ㈷䜚䜎䛧䛯䜙ᖾ⏒䛻Ꮡ䛨ୖ䛢䜎䛩䚹௒ᖺᗘ䚸ಟ஢୍ᮇ⏕䜢㏦䜚ฟ䛩/,06 䝥䝻䜾䝷䝮䛾㐍ᤖ䛸䚸௒ᚋ䚸་⒪䞉௓ㆤ䛾⌧ሙ䛻䜲䝜䝧䞊䝅䝵䞁䜢䜒䛯䜙䛩 $,䠋,R7 䜈䛾ி㒔኱Ꮫ་Ꮫ㒊௜ᒓ⑓㝔䛾ྲྀ䜚⤌䜏䛾୍➃䛻䛴䛝䜎䛧 ᮏ௳㐃⤡ඛ䠖㻌 ி㒔኱Ꮫ኱Ꮫ㝔ᕤᏛ◊✲⛉䛶䛤⤂௓䛷䛝䜜䜀䛸ᛮ䛔䜎䛩䚹䛺䛚䚸ᙜ᪥䛤ฟᖍ㡬 ᩍᤵ㻌 ㏆⸨㻌 ㍤ᖾ䛡䜛᪉䛿䚸䛚ᡭᩘ䛺䛜䜙䚸䠑᭶䠎䠏᪥䠄ⅆ䠅䜎䛷䛻䚸ᑠ 䛈 ி㒔ᕷすி༊ி㒔኱Ꮫ᱇⫋ᐄ䚸䛚ྡ๓䚸䛤ᡤᒓ䚸䛤㐃⤡ඛ䜢䝯䞊䝹䜎䛯䛿 7HO䠖  㻌 )$;䠖 
)$; 䛻䛶䛚▱䜙䛫㡬䛝䜎䛩ᵝ䚸䛚㢪䛔⏦䛧ୖ䛢䜎 0RELOH
(PDLOWHUX\XNL#VFON\RWRXDFMS
䛩䚹㻌
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ଐ଺Ჴ  ࠰  உ  ଐ Ჴ ᧏‫ ئ‬Ჴ ᧏‫ ڼ‬Ჴ ኳʕᲶᚡᎍႆᘙ Ჴ ᳸ ᲴᲸ   ૿Ჴ Ҕ‫ܖ‬ᄂᆮᅹ ሥྸ౐Წ᨞‫˟ݱ‬ᜭܴӮ ˟Ჴ ‫ٻ‬ᓎ ᥟᲢҔ‫ ܖ‬74# ܴᧈᲣႇّᎍᲴ ɥஜ˦ʚ

Ტ.+/5 ȗȭǰȩȠܱ଀ᝧ˓ᎍ Ҕ‫ܖ‬ᢿᧈȷҔ‫ܖ‬ᄂᆮᅹᧈᲣบ᢫ ‫ٻ‬Ტ.+/5 ȦȋȃȈᧈ ‫ܖٻ‬ᨈҔ‫ܖ‬ᄂᆮᅹ૙੉Უ





ᡈᕲ᠗࠳

Ტ.+/5 ңᜭ˟‫ۀ‬Ճ ‫ܖٻ‬ᨈ߻‫ܖ‬ᄂᆮᅹ૙੉Უ

᱅ဋჷ‫ܨ‬Ტ.+/5 ਃ࢘૙੉ ᧽‫ޓ‬၏ᨈҔၲऴ‫˖إ‬ဒᢿᧈᲣʟ৖ӝႺ‫܇‬Ტ.+/5 ‫ٳ‬ᢿᚸ̖‫ۀ‬Ճ˟‫ۀ‬Ճ ࠔʮ࠯঺‫ܖٻ‬ᕤ‫ܖ‬ᢿ૙੉Უ

ᲶҔၲ߻‫ܖ‬ཎКᜒ๫˟ Ჴ ᳸ ᲴᲸ ૿ᲴҔ‫ܖ‬ᄂᆮᅹ έᇢᅹ‫ܖ‬ᄂᆮ౐Ძ᨞ǻȟȊȸܴӮ ˟Ჴ ன‫ ޛ‬షऔᲢҔ‫ܖ‬ȷ၏ᨈ‫ע‬ғ 74#Უ ๫ ᫆Ჴ ᕤдࠖƷࢫлƱᡲઃ ᳸ ǱȸǹưᎋƑǔҔ߻ᡲઃᜒ ࠖᲴ ࠔʮ࠯঺‫ܖٻ‬ᕤ‫ܖ‬ᢿ ૙੉  ʟ৖ӝ Ⴚ‫ ܇‬൞Ƃᜒ๫˟ኳʕࢸŴࡽƖዓƖŴʟ৖ӝέဃƴǑǔ .+/5 ȗȭǰȩȠ
‫̲ޗ‬ဃƱƷǰȫȸȗȯȸǯᲢǱȸǹǹǿȇǣᲣǛᘍƍǇƢŵƃ䛆ி㒔኱Ꮫ་Ꮫ㒊ᵓෆᅗ䛇㻌

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⟶⌮Ჷ䠎㝵㻌⟶⌮Ჷ ⟶⌮Ჷ  㝵
ᑠ఍㆟ᐊ㻌
ᑠ఍㆟ᐊ

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Training Program of Leaders for Integrated Medical System
for Fruitful Healthy-Longevity Society (LIMS)Ҧٟᛢᆉ૙Ꮛ∐∞⇭⇉∙⇖⇽∓⇖∏∆‒

඘ᐇࡋࡓ೺ᗣ㛗ᑑ♫఍ࢆ⠏ࡃ⥲ྜ་⒪㛤Ⓨ࣮ࣜࢲ࣮⫱ᡂࣉࣟࢢ࣒ࣛ

 QG 0HGLFDO7HFKQRORJ\
6SHFLDO/HFWXUH
0D\

  

ᇹᲬ‫ ׅ‬Ҕၲ߻‫ܖ‬ཎКᜒ๫˟๫᫆ ᕤдࠖƷࢫлƱᡲઃ

᳸ǱȸǹưᎋƑǔҔ߻ᡲઃ᳸ᜒࠖ ʟ৖ӝႺ‫܇‬ࠔʮ࠯঺‫ܖٻ‬ᕤ‫ܖ‬ᢿ ૙੉ଐ଺ Ჯஉ  ଐ ້ ᳸
ᲫᲯᲴᲫᲯ᳸ᲫᲯᲴᲯᲯᲢᜒ๫Უ
ᲫᲰᲴᲪᲯ᳸ᲫᲱᲴᲮᲯᲢǰȫȸȗȯȸǯᲣ‫ئ‬৑ Ҕ‫ܖ‬ᢿನϋέᇢᅹ‫ܖ‬ᄂᆮ౐Ძ᨞ǻȟȊȸܴŨ .+/5 ȗȭǰȩȠưƸŴɥᚡƷཎКᜒ๫˟Ǜ᧏͵ᐲƠǇƢŵ‫ڠ‬ƬƯƝӋь᪬ƖǇƢᵝŴƝకϋဎƠɥƛǇƢŵ䛆䛚ၥ䛔ྜ䜟䛫䛇
ி㒔኱Ꮫ Ꮫ㝿⼥ྜᩍ⫱◊✲᥎㐍䝉䞁䝍䞊೺ᗣ㛗ᑑ♫఍䛾⥲ྜ་⒪㛤Ⓨ䝴䝙䝑䝖䠄>/D^䠅஦ົᐊ㻌 d>䠖ϬϳϱͲϳϱϯͲϵϯϯϰͲD/>䠖ŝŶĨŽΛůŝŵƐ͘ŬǇŽƚŽͲƵ͘ĂĐ͘ũƉ㻌 㻌 ,W䠖ŚƚƚƉ͗ͬͬǁǁǁ͘ůŝŵƐ͘ŬǇŽƚŽͲƵ͘ĂĐ͘ũƉͬグ⪅఍ぢ࣭➨㸰ᅇ་⒪ᕤᏛ≉ูㅮ₇఍ 㛤ദᴫせᖹᡂ  ᖺ  ᭶  ᪥ ⅆ 㹼 グ⪅Ⓨ⾲㸦་Ꮫ㒊ᵓෆ⟶⌮Ჷ  㝵ᑠ఍㆟ᐊ㸧㸦෗┿ୖᕥ㸧グ⪅఍ぢᴫせ࡟ࡘ࠸࡚ㄝ᫂ࡍࡿୖᮏᐇ᪋㈐௵⪅㸦ୖྑ㸪ୗྑ㸧ᕤᏛᢏ⾡࡬ࡢᮇᚅ࡟
ࡘ࠸࡚Ⓨ⾲ࡉࢀࡿ㧗ᢡ≉ᐃ෸ᩍᤵ㸪ᒸ⏣≉ᐃ෸ᩍᤵ㸦ୗᕥ㸧⸆Ꮫⓗぢᆅ࠿ࡽ /,06 ᒚಟ⏕࡬ࡢᮇ
ᚅࢆ㏙࡭ࡽࢀࡿ஭ᡭཱྀㅮᖌ㸦ୗ୰㸧$,,R7 ࡬ࡢ་Ꮫ㒊㝃ᒓ⑓㝔ࡢྲྀࡾ⤌ࡳ࡟ࡘ࠸࡚Ⓨ⾲ࡉࢀࡿ㯮⏣ᢸᙜᩍᤵ
㧗ᢡ≉ᐃ෸ᩍᤵ࣭ᒸ⏣≉ᐃ෸ᩍᤵࡼࡾ᭱ඛ➃ࡢእ⛉⮫ᗋ࡜⮫ᗋ་⒪⏬ീࡢ⌧ሙ࠿ࡽ་⒪ᕤᏛ࡬
ࡢᮇᚅࢆ㏙࡭ࠊ/,06እ㒊ホ౯ጤဨ఍ጤဨ࡛࠶ࡿᖹᡂ኱Ꮫ⸆Ꮫ㒊஭ᡭཱྀ┤Ꮚᩍᤵࡼࡾᮏ᪥ࡢ་⒪ᕤ
Ꮫ≉ูㅮ₇఍࡟ࡘ࠸࡚ᴫせࢆㄝ᫂ࡋࡓࡢࡕࠊ㯮⏣་⒪᝟ሗ௻⏬㒊㛗ࡼࡾࠕி኱⑓㝔ࡢ᝟ሗᡓ␎ ,R7$ ᫬௦࡬ྥࡅ࡚ࠖࡢㄝ᫂ࡀ࠶ࡗࡓࠋࡑࡢᚋグ⪅㉁ၥࡀ⾜ࢃࢀࠊ/,06 ᒚಟ⏕ࡢ㐍㊰ࡸி኱⑓㝔ࡢ㟁Ꮚ࢝ࣝࢸ࡟ࡘ࠸࡚ࡢලయⓗࠊヲ⣽࡞㉁ၥࡸࠊ⸆ᝈ ,7 ࡢ౛ࠊ་ᕤศ㔝࡛᪥ᮏࡀ㐜ࢀ࡚࠸ࡿ㡿ᇦࠊ⫱ᡂࡍ࡭ࡁ㡿ᇦࡣఱ࠿ࠊ࡞࡝ࠊ་ᕤ⸆ᝈࡢ⼥ྜ࡟ᑐࡍࡿᮇᚅࡢ㧗ࡲࡾࢆ཯ᫎࡋࡓ㉁ၥࡀᢞࡆ
ࡽࢀࡓࠋ ࡟ࡣ་⸆⤒῭♫࣭5,6)$; ࡟࡚㸪 ࡟ࡣ⸆஦᪥ሗ࡟࡚ሗࡌࡽࢀࠊ㛵ᚰࡢ㧗ࡉࡀఛࢃࢀࡓࠋ 㯮⏣ᩍᤵࠊ஭ᡭཱྀእ㒊ホ౯ጤဨ࡟ࡣⓎ⾲ෆᐜࢆࢥ࣒ࣛ࡜ࡋ࡚ /,06 ࣮࣒࣮࣍࣌ࢪ࡟ࡶᥖ㍕࠸ࡓࡔ
࠸ࡓࠋヲ⣽ࡣୗグ 85/ ཧ↷ࠋ࣭ி኱⑓㝔ࡢ᝟ሗ໬ᡓ␎㸫་⒪᝟ሗᏛࡢ⌧ሙ㸫 㯮⏣▱ᏹᩍᤵ /,06 ࣮࣒࣮࣍࣌ࢪࢥ࣒ࣛ
KWWSZZZOLPVN\RWRXDFMSFROXPQMSFROXPQBNXURGDM࣭ᆅᇦໟᣓࢣ࢔᫬௦ࡢ೺ᗣࢧ࣏࣮ࢺࡣ་ᕤ㐃ᦠ࡛㸟 ஭ᡭཱྀ┤Ꮚእ㒊ホ౯ጤဨ /,06 ࣮࣒࣮࣍࣌ࢪࢥ࣒ࣛ
KWWSZZZOLPVN\RWRXDFMSFROXPQMSLGHJXFKL㹼 ➨㸰ᅇ་⒪ᕤᏛ≉ูㅮ₇఍㸦་Ꮫ㒊ᵓෆඛ➃⛉Ꮫ◊✲Ჷ㸯㝵ࢭ࣑ࢼ࣮ᐊ㸧                    㸦ୖᕥ㸧ྖ఍ࢆࡉࢀࡿᮡᒣ་Ꮫ࣭⑓㝔ᆅ༊ 85$㸦ୖ୰㸧ㅮ₇ࢆࡉࢀࡿ஭ᡭཱྀㅮᖌ
㸦ୖྑ㸧⫈ㅮࡍࡿ /,06 ᒚಟ⏕㸦ୗᕥ㸧ࢢ࣮ࣝࣉ࣮࣡ࢡࢆ⾜࠺ /,06ᒚಟ⏕㸦ୗྑ㸧)DFHERRN ࢖࣋ࣥࢺ࿌▱ࡑࡢᚋඛ➃⛉Ꮫ◊✲Ჷ㸯㝵ࢭ࣑ࢼ࣮ᐊ࡟࡚⾜ࢃࢀࡓ➨㸰ᅇ་⒪ᕤᏛ≉ูㅮ₇఍࡛ࡣࠊ/,06 ࣉࣟࢢ࣒ࣛࡢእ㒊ホ౯ጤဨ࡟ࡶᑵ௵࠸ࡓࡔ࠸ࡓᖹᡂ኱Ꮫ⸆Ꮫ㒊஭ᡭཱྀ┤Ꮚᩍᤵࡼࡾࠊ
ࠕ⸆๣ᖌࡢᙺ๭࡜
㐃ᦠ㹼ࢣ࣮ࢫ࡛⪃࠼ࡿ་ᕤ㐃ᦠ㹼ࠖ࡜㢟ࡋࠊᆅᇦໟᣓࢣ࢔ࢩࢫࢸ࣒ࡢ୰࡛࠿࠿ࡾࡘࡅ⸆๣ᖌ࡜ࡋ
࡚ᝈ⪅ࡔࡅ࡛࡞ࡃᮍ⑓⪅ࡲ࡛ྵࡴࢥ࣑ࣗࢽࢣ࣮ࢩࣙࣥࡢ㔜せᛶࢆࢃ࠿ࡾࡸࡍࡃࡈㅮ₇࠸ࡓࡔ࠸ࡓࠋ
࣮࣡ࢡࢩࣙࢵࣉࠕ་ᕤ㐃ᦠ࡟㛵ࢃࡿᝈ⪅ࡢ୺యⓗ 42/ ホ౯࡜ࢥ࣑ࣗࢽࢣ࣮ࢩ࡛ࣙࣥࠖࡣࠊᒚಟ⏕ྠኈࡢ㉁ၥ࡜ࣇ࢕࣮ࢻࣂࢵࢡ࠿ࡽࡣࡌࡵࠊᐇ㝿ࡢᝈ⪅ࡢ౛ࢆ⏝࠸ࡓ࣮ࣟࣝࣉࣞ࢖ࢆ஺࠼࡞ࡀࡽ
6(,4R/ ಶேࡢ⏕άࡢ㉁ホ౯ἲ ࢆᐇ㝿࡟࠾ࡇ࡞ࡗࡓࠋ
ᒚಟ⏕ྵࡵ⣙  ྡࡢᏛ⏕ࠊࢫࢱࢵࣇࡀཧຍࡋࠊ⸆࣭ᝈ㐃ᦠࡢ⌧ሙ࡟࠾ࡅࡿࢥ࣑ࣗࢽࢣ࣮ࢩࣙࣥࡢ㔜せᛶࢆᏛࡧࠊ㞴⑓ᝈ⪅⮬ࡽࡢ♫఍㈉⊩࡬ࡢ㩭Ⅿ࡞ᛮ࠸࡜࡜ࡶ࡟ᚰ࡟ṧࡿࡇ࡜࡜࡞ࡿ࡛࠶ࢁ࠺ࠋ㻌ᖹᡂ䠎䠕ᖺ䠍䠍᭶䠒᪥㻌ᰴᘧ఍♫㻌 ་⸆⤒῭♫㻌௦⾲ྲྀ⥾ᙺ♫㛗㻌 ⸨⏣㻌 ㈗ஓ㻌 ᵝ㻌㻾㻵㻿㻲㻭㼄㻌 ᵐ䞄ᇐ㻌 ᬛᙪ㻌 ᵝ㻌 㻌ி㒔኱Ꮫ /,06 䝥䝻䜾䝷䝮㻌 ➨䠏ᅇ㻌 䛂་⒪ᕤᏛ≉ูㅮ₇఍䛃䡚 ㄆ▱⑕䜿䜰䛛䜙ᴟ䜑䜛㉸㧗㱋♫఍䜈䛾┳ㆤᏛ䛾♫఍ᐇ⿦ 䡚䛂ㄆ▱⑕◊✲䛾ୡ⏺ⓗ䛺₻ὶ䛃 䛚䜘䜃 䛂෌⏕ᅔ㞴䛺⤌⧊䛾෌⏕་⒪䛸䝸䝝䝡䝸䝔䞊䝅䝵䞁䛃ி㒔኱Ꮫ䛷䛿䚸䇾᭱ඛ➃䛾་Ꮫ䛾ᩍ⫱䞉◊✲⎔ቃ䛻䚸ᕤᏛ䛾Ꮫ⏕䛜᪩䛟䛛䜙ゐ䜜䚸་⒪䛾᪂䛧䛔㡿ᇦ䜢㛤ᣅ䛩䜛ᚲ↛ᛶ䜢Ꮫ䜆䚹䇿㻌 䛸䛔䛖ᴫᛕ䛾ୗ䚸㒊ᒁ㛫䛾ᇉ᰿䜢㉺䛘䛯་ᕤ㐃ᦠ䛾䠑ᖺ୍㈏༤ኈㄢ⛬ᩍ⫱䝸䞊䝕䜱䞁䜾䝥䝻䜾䝷䝮䜢ᐇ᪋䛧䛶䛔䜎
䛩䚹/,06䠄/HDGHUV IRU ,QWHJUDWHG 0HGLFDO 6\VWHP䠅䛸ྡ௜䛡䜙䜜䛯ᮏ䝥䝻䜾䝷䝮䛿䚸ᖹᡂ䠎䠐ᖺ䛻ᩥ㒊⛉Ꮫ┬䞉䠄⊂䠅᪥ᮏᏛ⾡᣺⯆఍䛂༤ኈㄢ⛬ᩍ⫱䝸䞊䝕䜱䞁䜾䝥䝻䜾䝷䝮䛃䛻᥇ᢥ䛥䜜䜎䛧䛯䚹䛭䛧䛶䚸᮶ᖺ䠏᭶䛻➨୍ᮇ⏕䛜♫఍䛻⩚䜀䛯䛟ணᐃ䛷䛩䚹䛥䛶䚸/,06 䛷䛿䚸➨䠏ᅇ䛂་⒪ᕤᏛ≉ูㅮ₇఍䛃䜢䚸᮶䜛䠍䠍᭶䠎䠍᪥䠄ⅆ䠅䛾༗ᚋ䛻㛤ദ⮴䛧䜎䛩䚹ㅮᖌ䛸䛧䛶䚸኱㜰኱Ꮫ኱Ꮫ㝔་Ꮫ⣔◊✲⛉䛛䜙⪁ᖺ┳ㆤ◊✲䛜䛤ᑓ㛛䛷䚸┳ㆤ䛾ᐇ㊶ⓗ䜶䝡䝕䞁䝇䜢ྲྀ䜚䜎䛸䜑䜛ᅜ㝿ᶵ㛵 -%,䠄-RDQQD %ULJJV,QVWLWXWH KWWSMRDQQDEULJJVRUJ䠅䛾᪥ᮏ௦⾲䜢ົ䜑䜛ᒣᕝ䜏䜔䛘ඛ⏕䜢䛚ᣍ䛝䛧䚸䛂ㄆ▱⑕䜿䜰䛛䜙ᴟ䜑䜛㉸㧗㱋♫఍䜈䛾┳ㆤᏛ䛾♫఍ᐇ⿦䛃䛸㢟䛧䛯ᤵᴗ䜢䛚㢪䛔䛧䛶䛚䜚䜎䛩䚹๓༙䛿䚸ᕤᏛ◊✲⪅䛜▱䜙䛺䛔┳ㆤ䛾ୡ⏺䛻䛴䛔䛶䛚ヰ䛔䛯䛰䛝䚸䛣䜜䛛䜙┈䚻㔜せど䛥䜜䜛┳ᕤ㐃ᦠ䛾㔜せᛶ䜢 /,06 ᒚಟ⏕䛜⪃䛘䜛ዎᶵ䛻䛧䛯䛔䛸ᛮ䛔䜎䛩䚹ᚋ༙䛿䚸┳ㆤ㡿ᇦ䜈䛾ᕤᏛⓗ䜰䝥䝻䞊䝏䛻䛴䛔䛶䚸䛥䜙䛺䜛Ὕᐹ䜢῝䜑䜛┠ⓗ䛷 /,06 ᒚಟ⏕䛾ཧຍయ㦂ᆺ࣮࣡ࢡࢩࣙࢵࣉࢆ⾜࠸ࡲࡍࠋ
䛴䛝䜎䛧䛶䛿䚸ᮏㅮ₇఍䛻ඛ❧䛱䚸ู⣬䛾䛸䛚䜚グ⪅఍ぢ䜢㛤ദ䛩䜛ᡤᏑ䛷䛩䚹ሗ㐨㛵ಀ䛾ⓙᵝ䛻䛿䚸୓㇟䛚⧞䜚ྜ䜟䛫䛾ୖ䚸䛤ฟᖍ㈷䜜䜎䛧䛯䜙ᖾ⏒䛻Ꮡ䛨ୖ䛢䜎䛩䚹䜎䛪䚸/,06 䝥䝻䜾䝷䝮䛾㐍ᤖ䛻䛴䛔䛶䛿䚸ᮏᏛ་Ꮫ㒊㛗䞉་Ꮫ◊✲⛉㛗䛷䛒䜚 /,06 䝥䝻䜾䝷䝮ᐇ᪋㈐௵⪅䛾ୖᮏఙ஧ᩍᤵ䛛䜙䛤ㄝ᫂䛥䛫䛶㡬䛝䚸ᘬ䛝⥆䛝䚸䛂㞴἞ᛶ䜔෌⏕䛜ᅔ㞴䛺⤌⧊䛾෌⏕་⒪䛸䝸䝝䝡䝸䝔䞊䝅䝵䞁䛃䠄㟷ᒣ᭸ᶞ෸ᩍ
ᤵ䠅䚸䛚䜘䜃䛂ㄆ▱⑕◊✲䛾ୡ⏺ⓗ䛺₻ὶ䛸ศᏊ⏕≀Ꮫⓗ◊✲䛃䠄ᮌୗᙬᰤᩍᤵ䠅 ᮏ௳㐃⤡ඛ䠖㻌 ி㒔኱Ꮫ኱Ꮫ㝔ᕤᏛ◊✲⛉ᩍᤵ㻌 ㏆⸨㻌 ㍤ᖾ䛸䛔䛳䛯ி㒔኱Ꮫ་Ꮫ◊✲⛉䛾ྲྀ䜚⤌䜏䛈 ி㒔ᕷすி༊ி㒔኱Ꮫ᱇䜢䛤⤂௓⮴䛧䜎䛩䚹
7HO䠖  㻌 ᙜ᪥䚸䛤ฟᖍ㡬䛡䜛ሙྜ䛻䛿䚸䠍䠍᭶䠍)$;䠖 
䠑᪥䠄Ỉ䠅䜎䛷䛻䚸䝯䞊䝹䛻䛶ᑠ⫋䜎䛷䛚
0RELOH
▱䜙䛫㡬䛝䜎䛩ᵝ䚸䛚㢪䛔⏦䛧ୖ䛢䜎䛩䚹 (PDLOWHUX\XNL#VFON\RWRXDFMS
/,06 䛻㛵䛧䜎䛧䛶䛿 KWWSZZZOLPVN\RWRXDFMS 䜒䛤ཧ↷䛟䛰䛥䛔䚹グ㻌㻌㻌᪥᫬䠖㻌 㻞㻜㻝㻣 ᖺ䠍䠍᭶䠎䠍᪥㻌 㻝䠎䠖㻟㻜㻌 㛤ሙ 㻝䠏䠖㻜㻜㻌 㛤ጞ 㻝㻣䠖䠌䠌㻌 ⤊஢㻌㻌㻌䠘ሗ㐨Ⓨ⾲㻌 㻝䠏䠖㻜㻜㻌 䡚㻌 㻝䠐䠖䠏㻜䠚㻌 ᪊䠖㻌 ་Ꮫ◊✲⛉㻌 ⟶⌮Ჷ䠎㝵ᑠ఍㆟ᐊ㻌㻌Ⓩቭ⪅䠖㻌 ୖᮏ㻌 ఙ஧㻌䠄㻸㻵㻹㻿㻌 䝥䝻䜾䝷䝮ᐇ᪋㈐௵⪅㻌 ་Ꮫ㒊㛗䞉་Ꮫ◊✲⛉㛗䠅㻌㻌㻌

㏆⸨㻌 ㍤ᖾ㻌䠄㻸㻵㻹㻿㻌 ༠㆟఍ጤဨ㻌 ኱Ꮫ㝔ᕤᏛ◊✲⛉䞉ᩍᤵ䠅㻌㻌㻌㊊❧㻌 ኊ୍㻌 䠄㻸㻵㻹㻿㻌 ᢸᙜ㻌 ኱Ꮫ㝔་Ꮫ◊✲⛉䞉ᩍᤵ䠅㻌 㻌㻌㻌ᒣᕝ㻌 䜏䜔䛘㻌 䠄㻸㻵㻹㻿 እ㒊ホ౯ጤဨ㻌 ኱㜰኱Ꮫ㻌 ኱Ꮫ㝔་Ꮫ⣔◊✲⛉䞉෸ᩍᤵ䠅㻌㻌㻌ᮌୗ㻌 ᙬᰤ㻌䠄኱Ꮫ㝔་Ꮫ◊✲⛉䞉ᩍᤵ䠅㻌㻌㻌㟷ᒣ㻌 ᭸ᶞ㻌䠄኱Ꮫ㝔་Ꮫ◊✲⛉䞉෸ᩍᤵ䠅㻌㻌䠘➨ 㻟 ᅇ㻌 ་⒪ᕤᏛ≉ูㅮ₇఍㻌 㻝㻡䠖㻜㻜㻌 䡚㻌 㻝㻣䠖㻜㻜䠚㻌 㻌 㻌 ᪊䠖㻌 ᇶ♏་Ꮫグᛕㅮᇽ㻌㻌㻌㻌㻌₇㻌 㢟䠖㻌

ㄆ▱⑕䜿䜰䛛䜙ᴟ䜑䜛㉸㧗㱋♫఍䜈䛾┳ㆤᏛ䛾♫఍ᐇ⿦㻌ㅮ㻌 ᖌ䠖㻌ᒣᕝ㻌 䜏䜔䛘㻌 ඛ⏕䠄኱㜰኱Ꮫ㻌 ኱Ꮫ㝔་Ꮫ◊✲⛉ಖ೺Ꮫᑓᨷ㻌 ෸ᩍᤵ䠅㻌㻌Ƃʮᣃ‫ܖٻ‬Ҕ‫ܖ‬ᢿನϋ‫׋‬ƃTraining Program of Leaders for Integrated Medical System
for Fruitful Healthy-Longevity Society (LIMS)㻌
Ҧٟᛢᆉ૙ᏋȪȸȇǣȳǰȗȭǰȩȠ඘ᐇࡋࡓ೺ᗣ㛗ᑑ♫఍ࢆ⠏ࡃ⥲ྜ་⒪㛤Ⓨ࣮ࣜࢲ࣮⫱ᡂࣉࣟࢢ࣒ࣛ

 UG 0HGLFDO(QJLQHHULQJ
6SHFLDO/HFWXUH
1RYHPEHU  㹼 㻌ᇹᲭ‫ ׅ‬Ҕၲ߻‫ܖ‬ཎКᜒ๫˟๫᫆ᛐჷၐǱǢƔǒಊǊǔឬ᭗ᱫᅈ˟ǁƷჃᜱ‫ܖ‬Ʒᅈ˟ܱᘺᜒࠖ‫ ߷ޛ‬ǈǍƑ έဃଐ଺‫ܖٻ ܖٻ᧵ٻ‬ᨈҔ‫ܖ‬ኒᄂᆮᅹ
̬ͤ‫ݦܖ‬ૌ ϱ૙੉ உ  ଐᲢ້Უ ᳸ ᲫᲯᲴᲪᲪ ᳸ ᲫᲰᲴᲪᲪᲢᜒ፯Უ ᲫᲰᲴᲪᲪ ᳸ ᲫᲱᲴᲪᲪᲢȯȸǯǷȧȃȗᲣ

‫ئ‬৑



Ҕ‫ܖ‬ᢿನϋؕᄽҔ‫ܖ‬ᚡࣞᜒ‫ؘ‬Ũ .+/5 ȗȭǰȩȠưƸŴɥᚡƷҔၲ߻‫ܖ‬ཎКᜒ๫˟Ǜ᧏͵ᐲƠǇƢŵ‫ڠ‬ƬƯƝӋь᪬ƖǇƢಮŴƝకϋဎƠɥƛǇƢŵƂƓբƍӳǘƤƃʮᣃ‫ܖ ܖٻ‬ᨥᗡӳ૙Ꮛᄂᆮਖ਼ᡶǻȳǿȸͤࡍᧈ‫ݤ‬ᅈ˟ƷዮӳҔၲ᧏ႆȦȋȃȈᲢ.+/5ᲣʙѦܴ 6'.Ჴ
'/#+.ᲴKPHQ"NKOUM[QVQWCELR *2ᲴJVVRYYYNKOUM[QVQWCELRƂʮᣃ‫ܖٻ‬Ҕ‫ܖ‬ᢿನϋ‫׋‬ƃ➨㸱ᅇ་⒪ᕤᏛ≉ูㅮ₇఍グ⪅Ⓨ⾲࡟ࡘ࠸࡚
ᖹᡂ  ᖺ  ᭶  ᪥ࠐグ⪅Ⓨ⾲ ≉ูㅮ₇఍࡟ඛ❧ࡘグ⪅Ⓨ⾲࡛ࡣࠊ/,06 ࣉࣟࢢ࣒ࣛࡢ⌧ἣሗ࿌࡜ࡋ࡚ࠊእ㒊ホ౯ࡢᣑ඘࡜ホ౯ጤဨ࠿ࡽࡢពぢ࡟ᇶ࡙ࡃࣉࣟࢢ࣒ࣛࡢᨵၿ࡟ࡘ࠸࡚ࠊࡑࡢ୰࡛ࡶ≉࡟⑓㝔ᐇ⩦࡟ࡘ࠸࡚Ⓨ⾲ࡀ⾜ࢃࢀࡓࠋ㉁␲ᛂ⟅࡛ࡣࠊಟ஢⪅ࡢ㐍㊰࡟ࡘ࠸࡚ࠊࡉࡽ࡟་ᕤ㐃ᦠࡢၥ㢟Ⅼࡸ೺ᗣ㛗ᑑ♫఍ࡢᐇ⌧࡟ྥࡅࡓ་ᕤ㐃ᦠࡢ㔜せᛶ࡟ࡘ࠸࡚㆟ㄽࡀ⾜ࢃࢀࡓࠋࡲࡓࠊ
ࣉࣟࢢ࣒ࣛࡢ┠ᣦࡍ඘ᐇࡋࡓ೺ᗣ㛗ᑑ♫఍ࡢᐇ⌧࡬ྥࡅ࡚ࠊி㒔኱Ꮫ኱Ꮫ㝔་Ꮫ◊✲⛉࠾ࡼࡧ་Ꮫ㒊㝃ᒓ⑓㝔࡛⾜ࢃࢀ࡚࠸ࡿᵝࠎ࡞ྲྀࡾ⤌ࡳࡢ⤂௓࡜ࡋ࡚ࠊᮌୗᙬᰤᩍᤵࡼࡾ
ࠕ㞴἞ᛶࡸ෌⏕ࡀᅔ㞴࡞⤌⧊ࡢ෌⏕་⒪࡜ࣜࣁࣅࣜࢸ࣮ࢩࣙࣥࠖࠊ࠾ࡼࡧ㟷ᒣ᭸ᶞ෸ᩍ
ᤵࡼࡾࠕㄆ▱⑕◊✲ࡢୡ⏺ⓗ࡞₻ὶ࡜ศᏊ⏕≀Ꮫⓗ◊✲ࠖ࡟ࡘ࠸࡚ࡢ⤂௓ࡶ⾜ࢃࢀࡓࠋグ⪅Ⓨ⾲඲ᬒ

⑓㝔ᐇ⩦࡟ࡘ࠸࡚Ⓨ⾲ࡍࡿ㊊❧ே㛫೺ᗣ⛉Ꮫ⛉㛗ࠐ་⒪ᕤᏛ≉ูㅮ₇఍ ➨㸱ᅇࢆ㏄࠼ࡿ་⒪ᕤᏛ≉ูㅮ₇఍࡛ࡣࠊ኱㜰኱Ꮫ኱Ꮫ㝔་Ꮫ◊✲⛉ᒣᕝࡳࡸ࠼
෸ᩍᤵࢆㅮᖌ࡜ࡋ࡚ᣍ⪸ࡋࠊࠕㄆ▱⑕ࢣ࢔࠿ࡽᴟࡵࡿ㉸㧗㱋♫఍࡬ࡢ┳ㆤᏛࡢ♫఍ᐇ⿦ࠖ࡜㢟ࡍࡿㅮ₇࡜࣮࣡ࢡࢩࣙࢵࣉࢆᐇ᪋ࠊᒚಟ⏕ྵࡵ⣙  ྡࡢᏛ⏕ࠊࢫࢱࢵࣇࡀཧຍࡋ
ࡓࠋᒚಟ⏕ࢆ௦⾲ࡋ/ ᒚಟ⏕㸦኱Ꮫ㝔ே㛫೺ᗣ⛉Ꮫ⣔ᑓᨷಟኈ  ᅇ⏕㸧ࡢ๓⏣ಙኴ㑻ࡉࢇ࡟ࡼࡿሗ࿌ࢆᥖ㍕ࡍࡿࠋ ᖹᡂ  ᖺ  ᭶  ᪥ /,06་⒪ᕤᏛ≉ูㅮ₇఍࡜㢟ࡋ࡚ࠊ኱㜰኱Ꮫ኱Ꮫ㝔་Ꮫ⣔◊✲⛉ಖ೺Ꮫᑓᨷࡼࡾᒣᕝࡳࡸ࠼ඛ⏕ࢆ࠾ᣍࡁࡋ࡚ࠕㄆ▱⑕ࢣ࢔࠿ࡽᴟࡵࡿ㉸㧗㱋♫఍࡬ࡢ┳ㆤᏛࡢ♫఍ᐇ⿦ࠖ࡟ࡘ࠸࡚ㅮ₇ࡋ࡚࠸ࡓࡔ
࠸ࡓࠋᒣᕝඛ⏕ࡣබ┈㈈ᅋἲேὸ㤶ᒣ⑓㝔࡟࡚ᐇ㝿࡟ㄆ▱⑕ᝈ⪅࡜ゐࢀྜ࠸ࠊ᪥ࠎ࡝ࡢࡼ
࠺࡟ᙼࡽࢆ┳ㆤࡍࡿ࡭ࡁ࠿◊✲ࡉࢀ࡚࠸ࡿࠋ

ࡑࡢ⤒㦂࡟ᇶ࡙࠸࡚ࠊ๓༙࡛ࡣ㉸㧗㱋♫఍࡬ࡢኚ㑄࡜࡜ࡶ࡟ቑຍࡋ࡚࠸ࡿㄆ▱⑕ᝈ⪅ࡢࡓࡵ࡟ࡣ࡝ࡢࡼ࠺࡞┳ㆤࡀồࡵࡽࢀ࡚࠸ࡿࡢ࠿ࠊࡲࡓ
,R7ࡸ$,࡞࡝ࡢ᪂ࡋ࠸ᢏ⾡ࢆ฼⏝ࡋࡓ᪂ࡓ࡞
┳ㆤࡢᙧࠊᡃࠎ/,06ᒚಟ⏕ࡸᕤᏛ◊✲⪅ࡢ᪉࡬ࡢᮇᚅ࡞࡝ࢆ࠾ヰ࠸ࡓࡔ࠸ࡓࠋᚋ༙࡛ࡣ,QRFKL*DNXVHL)RUXP࡛ㄆ▱⑕ࡢㄢ㢟ゎỴࢆࢸ࣮࣐࡟Ꮫ⏕ࡓࡕࡀ⪃࠼ࡓVROXWLRQ౛ࡸࠊㄆ▱⑕ᝈ⪅ࡢ❧ሙ࡟࡞ࡗ࡚⪃࠼ࡿࡓࡵ࡟⾜ࢃࢀ࡚࠸ࡿㄆ▱⑕య㦂95࡟ࡘ࠸࡚⤂௓࠸ࡓࡔ࠸ࡓࠋ

௒ᅇࡢㅮ₇ࢆཷࡅࠊㄆ▱⑕ᝈ⪅ࡢࡓࡵ࡟ᮏᙜ࡟ồࡵࡽࢀ࡚࠸ࡿ┳ㆤࠊᢏ⾡࡜ࡣఱ࠿⪃࠼ࡓࠋ୍͇ᗘⓎ㐩ࡋࡓ▱⬟ࡀࠊ⬻ࡢ㒊఩ࡀኚ໬ࡍࡿࡇ࡜࡟ࡼࡾᗈ⠊ᅖ࡛⥅⥆ⓗ࡟పୗࡋࡓ≧ែ͇࡛࠶ࡿㄆ▱⑕ࡣᝈ⪅୍ே୍ே⑕≧ࡀ␗࡞ࡿࠋࡑࢇ࡞ㄆ▱⑕ᝈ⪅࡟ᑐࡍࡿ་⒪ࡢᙧ࡜ࡋ࡚ㅮ₇୰࡟Ⓩሙࡋࡓ (YLGHQFHEDVHGSUDFWLFH (%3 ࡟ࡣឤ㖭ࢆཷࡅࡓࠋ(%3࡜ࡣ◊✲࡟ࡼࡿHYLGHQFHࠊᐇ㝿࡟┳ㆤࠊ௓ㆤࠊ௨ୖ࡟⮫ᗋⓗ࡟ᦠࢃࡿᑓ㛛⫋ࡢ▱㆑ࡸࣀ࢘ࣁ࢘ࠊᝈ⪅ಶேࡢయ㦂ࡸႴዲࠊࡑࡢ௚ධᡭྍ⬟࡞᝟ሗࢆໟᣓⓗ࡟㚷ࡳࡓୖ࡛ࢳ࣮࣒
ෆ㸦἞⒪ࢆ⾜࠺ࡶࡢࠊᝈ⪅ࠊᐙ᪘➼㸧࡛ពᛮỴᐃࢆඹ᭷ࡋࠊᝈ⪅࡟᭱ࡶ๎ࡋࡓ἞⒪ࠊ௓
ㆤࢆᐇ㊶ࡍࡿࡇ࡜࡛࠶ࡿࠋ⚾ࡣ⮫ᗋ᳨ᰝᢏᖌࡢ㈨᱁ࢆ᭷ࡍࡿࡢ࡛ࠊ᳨ᰝᢏᖌ࡜ࡋ࡚ࡇࡢ
(%3࡟࡝ࡢࡼ࠺࡞ᙧ࡛ᦠࢃࢀࡿ࠿⪃࠼ࡓࠋࡑࢀࡣ⏕⌮ᶵ⬟᳨ᰝ㸦╧╀ࠊᚰ⫵ᶵ⬟ࠊ⬻ᶵ⬟➼㸧ࢆᐇ᪋ࡍࡿ㝿ࡢᝈ⪅ࡢ⢭⚄≧ែࢆࢳ࣮࣒ෆ࡛ඹ᭷ࡍࡿࡇ࡜࡛࠶ࡿࠋࡇࢀࡣ㛗࠸ࢫࣃ࡛ࣥᝈ⪅ࢆぢ࡚࠸ࡃୖ࡛࡝ࡢࡼ࠺࡞᳨ᰝ⤖ᯝࡢ᫬࡟ㄆ▱⑕ࡢ⑕≧ࡀฟࡸࡍ࠸ࡢ࠿᥎
ࡍࡿࡓࡵ࡟᭷⏝࡛࠶ࡿ࡜⪃࠼ࡿࠋ
ࡲࡓㅮ₇ࡢᚋ༙࡛⤂௓࠸ࡓࡔ࠸ࡓ,QRFKL*DNXVHL)RUXP࡛ࡢ㧗ᰯ⏕ࡓࡕࡢⓎ⾲ࡢ୰࡛ᐇ㝿࡟ㄆ▱⑕ᝈ⪅ࢆᐙ᪘࡟᭷ࡍࡿࢢ࣮ࣝࣉࡢไసࡢ㐣⛬࡟ࡣ⪃࠼ࡉࡏࡽࢀࡿࡶࡢࡀ࠶ࡗࡓࠋㄆ
▱⑕ᝈ⪅ࡢ⧞ࡾ㏉ࡋྠࡌࡇ࡜ࢆヰࡋ࡚ࡃࡿ≧ែ࡟ᑐࡍࡿゎỴἲ࡜ࡋ࡚ࠊྠࡌ
ෆᐜࢆヰࡋࡓᩘࡔࡅ࢝࢘ࣥࢺࡋ࣏࢖ࣥࢺ࡜ࡋ࡚㈓ࡵࡿࡇ࡜ࡀ࡛ࡁࠊ㈓ࡵࡓ࣏࢖ࣥࢺ࡟ᛂ
ࡌ࡚ၟရๆ࡜஺᥮࡛ࡁࡿ࡜࠸࠺࢔࢖ࢹ࢔ࢆᥦ᱌ࡋࡓࠋ➨୕⪅ࡢどⅬ࠿ࡽ⪃࠼ࡿ࡜ㄆ▱⑕ࡢ⑕≧ࢆ࢝࢘ࣥࢺࡋ࡚࣏࢖ࣥࢺ࡜ࡋ࡚฼⏝ࡍࡿࡢࡣ೔⌮ⓗ࡟࡝࠺࡞ࡢ࠿࡜ᛮ࠺ࡀࠊᙜ஦
⪅࠿ࡽࡍࢀࡤࡇࢀ࡛ㄆ▱⑕ᝈ⪅ࡢᐙ᪘ࡢ┦ᡭࢆࡍࡿࢫࢺࣞࢫࡀ㍍ῶࡉࢀࡿࡢ࡞ࡽࠊࡑࢀ
࡛Ⰻ࠸࡜ࡑࡢࢳ࣮࣒ࡣ཯ㄽࡋࡓࡢ࡛࠶ࡿ㸦᭱⤊ⓗ࡟ࡣูࡢ࢔࢖ࢹ࢔ࢆᥦฟࡋࡓ࡜ࡢࡇ࡜
ࡔࡗࡓ㸧ࠋࡇࡢ᫬ࠊఱ஦࡟ࡶᙜ஦⪅ព㆑ࡀᚲせ࡛࠶ࡿ࡜⪃࠼ࡉࡏࡽࢀࡓࠋㄆ▱⑕ᝈ⪅ࡢ❧ሙ࡟࡞ࡿࡇ࡜ࡶࠊㄆ▱⑕ᝈ⪅ࡢᐙ᪘ࡢ❧ሙ࡟࡞ࡿࡇ࡜ࡶㄆ▱⑕ᝈ⪅ࡢ┳ㆤࠊ௓ㆤ࡟ᙜ
ࡓࡿୖ࡛㔜せ࡞ࡇ࡜࡛࠶ࡿࠋᡃࠎ/,06 ᒚಟ⏕ࡀ་⒪⌧ሙ࡟ᮏᙜ࡟ᚲせ࡞ࡶࡢࢆ⪃࠼ฟࡍୖ࡛ᚲせ࡞⪃࠼᪉ࢆᏛࢇࡔࡼ࠺࡟ឤࡌࡿࠋ

$FWLYLW\UHSRUWIRU3URJUDPIRU/HDGLQJ*UDGXDWH6FKRROV)RUXP
(Nagoya Marriott Associa Hotel, Nagoya, from October 19th to 21st, 2017)
Yu KIMURA (Program-Specific Associate Professor, LIMS)
In this Forum, over-one-thousand attendees, including persons from all 62
programs of The Program of Leading Graduate Schools and 149 individuals related tocompanies, gathered to highlight the legacies from the respective programs and discuss
how they can endow future graduate students with prospective opportunities, under thetheme “PhDs shaping the Future, PhD programs investing in the Future”. From LIMS,
6 students and 3 teachers were participated including pre-forum discussion and poster
presentations. In this forum, there are consisted from Keynote speech, ParallelWorkshops, Poster session, and Panel discussion and discussed mainly about summaryof interim appraisal, report from Central Education Council, future plan of the programs
including Also prior to the forum, pre-forum discussion on career development wasorganized.Students were divided into groups to discuss about their career development
as Ph, D. candidates, then they made proposals towards industry, government andacademia. From LIMS, Mr. Hakariya attended to the Pre-forum Discussion A.
Thereat,severalstudents(Mr.

Miyanohara, Mr. Nishitani and Mr. Hakariya)
had poster presentation in the forum. Students
presented how to make use of skills theyacquired through LIMS activities and to apply
towards their career development and they
enjoyedanimated

discussion

with

all

attendants. In day 2, explanatory session for“Takuetsu” Graduate Schools was held with allattendants

includingprogramstudents.

Strategy introduction of establishing that
Grad. Schl. from MEXT would be useful
information for us.

Photo:

LIMS

attendees

atpostersessionroom.

(SpecialThanksto

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ͦ͠Ζ͞ͳͲɼജ৏༩଎Ώ໐࿯ϟ

ΖͳൾΗͬΎͮͪΕɼ‫ݡ‬ಂͪ͢ΕͤΖΞͣʖϩϓΡϩνʖ͵ʹ͹༩଎մੵ͗

Ύ͵͏͖ͮͱ͏͑ͳ͞ΘͲึঁదͶ࢘ͮͱՆ೵ͳ͵ͮͱ͏Ήͪ͢ɽͨΗ͗࠹ۛ͹ٗढ़͏ͪͫͪ͜Δɼͳࢧ͏Ήͤɽַ৿ͶΓΕɼժ଀Ώಊժͳ͏ͮͪ‫ְ״‬ద͵੤  ۫ରదͶͺ‫౐ښ‬୉ָබӅ͹ਕͳʃ ଲেͶଲ͢ͱ΍ɼգ‫ڊ‬͹υʖνͶ‫ͱ͏Ͱخ‬ԗ໼ ‫౐ښ‬୉ָ͹ҫָ‫ڂݜ‬Ռͳ΍‫ڂݜ‬ͺߨͮͱ͏εητϞ͗൓இΝߨ͓ΖΓ͑Ͷ͵ͮͱ͘ΉΉͤɽଠͶͺฎ‫ݟށ‬͹‫ء‬ՌබӅ ஭  ͳ΍఑ͪ͢ɽҫྏ‫Ͳܐؖ‬෾͖ΕΏͤ͏ྭΝ‫͝ڏ‬Ζ‫͏ͱ͢ܠ‬Ήͤɽҫྏ‫ܧ‬Ґ֐Ͳͺɼࣙಊऄ‫ؖ‬ͳɼྭ͓ͻ୉ྖ͹‫ं׳‬͹ &7 ժ଀Ν༽͏ͱ‫ܐ‬ΏηϜʖφϓΧϱɼใૹ‫ܐؖ‬͹੣ଆ‫ۂ‬͹ָसͦͪ͠εητϞΝ༽͏ͱɼʹ͞Ͷ࣮‫׳‬ժ଀‫ࠬݗ‬΍ߨͮͱ͏Ήͤɽ؈ୱͶ‫ͳ͑ݶ‬ɼ

͍͗Ζ͖Ν‫ݗ‬எ͢Γ͑ͳ͏͑ࢾΊͲͤɽਕ͗໪ࢻͲߨͮͱ͏Ζ੣඾Ώોࡒ͹න໚Ͷ੤  ԗ໼͚Ξ͗Ώͮͱ͏Ζ͹ͺॄΌΖ͞ͳʃͨΗͳ΍ϕϫήϧϞΝࡠΖ͞ͳʃ ͍Ζҡ෼Ώϖαϝͳ͏ͮͪҡ৙‫ࠬݗ‬Νɼਕ޽எ೵ٗढ़Ν༽͏ͱࣙಊԿͤΖΓ͑͵࢕ࣆԗ໼ સ෨Ͳͤ͸ɽ࠹ॵͶබӅ͹๏͖Δ໲͏߻ΚͲͤɽॊཔ͹ժ଀‫ࠬݗ‬εητϞͳҩ͏ɼਕͦΝ௘͏ͱʰ͞ΗΝΏͮͱΊͪ͏ʱͳ૮஌

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͚ΗΖͮͱ͏͑͞ͳͲ͖ͤʃԗ໼ ͨ͑͏͑͞ͳͲͤ͸ɽ੤  ͨΗ͗ࠕ͹࢕ࣆ͹Ҳ൬͹஬ʃԗ໼ ࠕ͹ͳ͞Θͨ͑ͲͤɽҲൢϤʖδʖ޴͜͹੤  ࢢ‫ڛ‬͹͞Θ͖Δ͹ໂͫͮͪ͜ʹɼ۫ର੓ͺ͵͖ͮͪΞͲͤ͸ʞʃγʖϑηΏΠϕϨͲͺ͵͏͹Ͳɼ͍ΉΕஎԗ໼ ͨ͑Ͳͤɽͨ͑͏͑ਕͶ͵ΗͪΔͳࢧͮͱ

ΔΗΖ͞ͳͺ͵͏྘ҮͲͺ͍ΕΉͤɽͲͤ͏Ήͪ͢ɽԿָͺඉ৙Ͷඔ͚͢ͳͱ΍ֺ͗͢ऀճదͶ΍ਕघ෈ଏ͗‫ͻڥ‬Ηͱ͏Ζ྘Ү͖ͮͪΞͲͤ͗ɼࢾ‫ݩ‬؇͹஦ͫ͜Ͳͺ͵͚͹ͪΌɼ໲͏߻Κͦ΍ଡ͚ඉ৙ͶΏΕ͗͏΍͑ঙ͢੊͹஦Ώऀճ΃໪Ν޴ͪ͜͏ͳ Ν‫͏ͱͣ״‬ΉͤɽΑ͚Α͚ͺҲൢϤʖδʖյਫ਼͹‫ޛ‬ൔ͖Δࢧ͑Γ͑Ͷ͵ΕΉͪ͢ɽͨ޴͜Ͷ΍ཤ༽͠ΗΖΓ͑͵γʖϑη΍ࡠͮ͞ͲԢ༽‫ܧ‬͹͞ͳΝ͢Γ͑ͳ /,06 Ͷͺ೘ͱ͏͜Ηͻ͏͏͵ͳࢧͮͱ͏ΉͤɽΕɼබӅࣰस͵ʹΝ௪͢ͱࣰऀճ͹՟ୌͶ੤  ԗ໼͚Ξ͗ϕϫήϧϞͤΖ͹ʃৰΗ߻͑‫ؽ‬ճ͗ಚΔΗΉͪ͢ɽྭ͓ͻ࠹ॵԗ໼ ๽΍αʖχॽ͏ͱ͏Ήͤ͜Ηʹ΍ɼ࠹ۛͺͺɼௗ͚೘Ӆ͢ͱ͏Ζ๏ʓͶ֐͹੊ֆΝ‫ݡ‬έϧ΢Πϱφͳ͹଩ͬ߻Κͦ͵ʹΝϟ΢ϱ

ͦΗͪΔͳߡ͓ɼ੊ֆ஦Ͷ͍ΖϋρφϭʖͲߨ͏ɼ‫ݳ‬৖͹՟ୌͶ޴͘߻͑࣎ؔΝଁΏέΩϟϧʀηϜϙ͹ΩϟϧΝ‫͛ܪ‬Հ૟ྃߨ͢ͱ͏Ήͤɽ

ϕϧρφϙʖϞ͹Γ͑͵΍͹ΝࡠΘ͖͑ͳ੤  ͠Δͮͳ͕ͮ͢ΎͮͱΉͪ͢͜Ηʹ΍ɽ΍ߡ͓Ήͪ͢ɽͨ͹‫ޛ‬ឱ༪‫ۄ‬઄Ν‫ͱܨ‬ɼ‫ͳء‬ͳ΍ͳϕϫήϧϝϱήͺΏͮͱ͏͵͖ͮͪ͏͑ਕ͹‫ׯحְ״‬Ν޽৖͹ࣅऄ͹Γ͑ͶࠇͲͤΓ͸

࢘͢ͱ͏Ζ໪ࢻ‫ࠬݗ‬͹੊ֆΝร͓ͱ͏͑͞ԗ໼ ָ෨࣎େͺΏͮͪ͞ͳ͍ΕΉͦΞͲͪ͢ɽͳɼ‫ࡑݳ‬͹Γ͑͵‫ܙ‬Ͷ͵ΕΉͪ͢ɽΠΩυͲ΍ /,06 Ͷ೘ͮͱɼ95ʤώʖοϡϩϨΠ

ϝΠͲਫ਼ΉΗͪ࠹઎୼͹ٗढ़Νɼࣰࡏ͹‫ݳ‬ϨτΡʥΊͪ͏͵ΞΏΘ͑ͮͱ͞ͳͲຌͳ

৖Ͳ͓࢘ΖΓ͑Ͷ서͢γʖϑηͶཚͳ͖͢ϏλαϱΝഛͮͱ΍Δͮͱ͖ͨ͞Δห‫ک‬ࠒ΋ӨΊͺɼ؈ୱͲͺ͵͏Ͳͤ͗ඉ৙Ͷ໚Ν࢟ΌΉͪ͢ɽ

പ͚‫͏ͱͣ״‬Ήͤɽ੤  ࠹ॵͶɼ୉ָ೘ͮͪͳ͘ͺʞʃԗ໼ ࠹ॵʃ ୉ָ͹Ҳյਫ਼͹࣎Ͳ͖ͤʃ੤  ್೧઴ͺʹ͹ஊ֌ͫͮͪΞͲ͖ͤʃ΍͑ࠕ͹ճऀཱིͬ৏͗ͮͱ͏Ήͪ͢ʃ੤  ͯΉΕͨ͹ɼ/,06 ͗ྒྷ͏Ӫ‫ڻ‬Ν༫͓ͪͮԗ໼ 0 ͹  ݆͖  ݆͖Δ  ݆຦ΉͲൔ೧ؔ६

ͱ͞ͳ͍͗Ζ͹͵Δซͪ͘͏͵ͳࢧͮͱɽ

ඍ‫ͱ͍ͮ͗ؔغ‬ʞͨ͹‫ޛ‬͹  ݆͖Δࣙ෾͹࠹ॵͺ͑ͫͮͪ͜͞ʹɼ/,06 ͹द‫͖ͳۂ‬ճऀΝ࢟ΌΉͪ͢ɽซ͏ͱʞͳ͖ɼ/,06 Ͷͳͮͱ͑Η͢͏࿫͗ซ͜͵͏͖͵͌ͳʞԗ໼ ซ͜Ήͤซ͜Ήͤɽ੤  ً‫ͱͮۂ‬อ‫࢞͠ޤ‬Ξͳ૮஌ͤΖΞͲ͖ͤʃΏΕ๏ͺʹ͑ΏͮͱָΞͫ͹Ͳ͖ͤʃԗ໼ ࣰͺ࠹ॵͶඉ৙Ͷ͕੊࿫Ͷ͵ͮͪ๏͗͏Ή੤  ʤ঺ʥ

ͪ͢ɽ‫ܜ‬Ԣ୉ָ͹ಝ೜‫گ‬द͹๏͵͹Ͳͤ͗ɼԗ໼ ΍ͳ΍ͳ‫ښ‬୉Ͷ೘ͮͪཀྵ༟ͺɼঘ͠͏͞Θͨ͹ਕ͗͏͵͜Ηͻɼࠕ͹ࣙ෾ͺ͏͵͏͖ͫΔ൅໎Պͳ͏͖͑ɼٗढ़Ν࢘ͮͱ੊͹஦Θ͑ͳࢧͮͱ͏ΉͤɽͶༀͶཱིͯ΍͹ΝࡠΕͪ͏ͳ͏͑૟͏͍͗੤  ͨ͹ਕͳ͹ड़ճ͏ͮͱ͏͑͹ͺʃ͖ͮͪΔͲͪ͢ɽͪͫ͢൅໎Պͳ͏͑৮‫ۂ‬ԗ໼ /,06 ࣎େͶೖ‫ܨ‬τέόϩϋγϱηक࠷͹ͺ͵͏͹ͲɼՌָंͶ͵Θ͑ͳɽՌָं͵αϱϘͲ༑ঋ ஭  ͪ͢͞ͳ͍͗ΖΞͲͤ

Δࢾ‫ݩ‬؇Ν৾ΖԿָ͖͵ͳࢧͮͱ୉ָ೘Ε͗ɼͨΗΝ͞͹๏͗क࠷͢ͱͪΞͲͤɽΉͪ͢ɽ੤  ͨ͞ͲஎΕ߻ͮͪ͹Ͳ͖ͤʃ

ԗ໼ ͨ͑Ͳͤɼೖຌ͹ஏҮऀճ͹՟ୌ͵ʹͶଲ࢘౏Ν੏‫͠ݸ‬ΗΖ‫׈͖͢Ͳ಼ۜࣁڂݜ‬ಊͲ͢ͱखΕૌΉΗͱ͏Ζ๏Ͳͤɽً‫ۂ‬Ν૮஌͘͵͏ೖຌ͹‫ंڂݜ‬ΓΕ΍ࣙ༟ౕ͗߶͏Ͳ

Ͳ͘Ζਕ͗͏͵͖ͮͪ͹Ͳ૮஌Ͷߨ͘Ήͤ͢͸ɽঀʓΝ‫ר‬ఈ͢ͱɼࣙ෾͹৖߻ͺҲਕͪɽ‫ݫ‬ʓͺϔʖϞͶ৒ͮͱϗϱοϡʖΫϡͲΏΕͪ͏ͳࢧ͏Ήͪ͢ɽϒνϩ͖Δ౦ࣁΝ΍ΔͮͱճऀΝ࢟ΌΓ͑੤  ࠕ͹ָਫ਼͠Ξ΃ঁ‫͍ݶ‬ΕΉ͖ͤʃͳ͢ͱ͏Ήͪ͗͢ɼ΍͑ͬΒͮͳͬΎΞͳԗ໼ ಝͶໃ͏Ͳͤ͗ɼৼ͹ఊ͖Δ޹͘ͶͤΗͻߡ͓ͪΆ͑͗͏͏ͩͳɼΠχώ΢ηΝ΍Δ͏͏ͳͺࢧ͏Ήͤɽͪͫɼʹ͑ͦಋͣ࣎ؔ

͏ཚͬ஥͖ͦͱ΍Δ͏Ήͪ͢ɽΝ /,06 ͲভඇͤΖ͵Δɼࠐ͹ਹΉͲΩϨ੤  ͨΗͺΓ͖ͮͪ͸ɽΫϣϧϞΝ͢Ύ΁Εਜ͚͢ͱ‫׬‬೵͢ͱɼࣙԗ໼ ͍͹ड़ճ͏͍͗Ζ͹ͳ͵͏͹Ͳͺɼ‫ࡑݳ‬͹෾͹ࠐ೓Ͷ͢ͱ͏ͮͪ๏͕͗ಚ͖͵ͳ‫ݺ‬ਕয়‫ڱ‬ͺรΚͮͱ͏ͪͳࢧ͏Ήͤɽ੤  ͍Ηͺ /,06 ಋָ೧͹নຌ͠Ξ͗ड़ͨ͑ͮ
ͱ‫ͱͮݶ‬ड़ͪ͢΍͹ͫΓ͸ɽԗ໼ ͨ͑Ͳͤ͸ɼ/,06 ͹͕͖͝Ͳྒྷ͏஧ؔͶదͶࢧ͏Ήͤɽ
੤

/,06 ͺ࠹ۛɼԗ໼͚Ξ͗͏ͪࠔͶͺ͵͖ͮͪ‫ښ‬୉බӅࣰसΝΏΕ࢟Όͱ͏ΖΞͲͤΓɽΆ͖Ͷͺ֐෨͹ਕɼ‫ं׳‬ճͳ͖ɼ͗Ξ͹‫ܛ‬ΉΗΉͪ͢ɽγώ΢ώʖͫͮͪΕ؅‫ࢥޤ‬͹઎ਫ਼ɼ༂ࡐࢥ੤  ͍Ε͗ͳ͑͟͡͏ΉͤɽͫͮͪΕΝ‫ݼ‬ΞͲߪԍճΝՁյ͖Ώͮͱ͏ԗ໼ ୉ָӅਫ਼Ͷ͵ͮͱ‫ڂݜ‬Ν࢟ΌΖͳ‫࣪ڂݜ‬ͶΉͤɽ͞΍Ε͗ͬͶ͵ͮͱ͢Ή͑͹Ͳɼଠ͹෾໼͹ਕͳިླྀͲ͘Ζ৖ͺ‫ͤͲ॑ي‬͸ɽ੤   ਕͲً‫ͤۂ‬Ζͮͱ‫͑ݶ‬͹ͺෑ͏͵͌ͳͺߡ͓͵͖ͮͪ͹Ͳ͖ͤʃԗ໼ ߡ͓Ήͪ͢͜ʹɼ͖ͫΔͨ͞  ਕͲͪ͢͏
ͳࢧ͏Ήͪ͢ɽࣙ෾͗ࣨഌ͢ͱଡঙ͹ईۜԗ໼ ๽͹࣎΍͏ΘΞ͵घढ़ΏϨύϑϨΝ௙井઎ਫ਼ͳ͖ͶҌ಼͢ͱ΍Δͮͪ͹Ͳɽ͍ΗͺΓ͖ͮͪͳࢧ͏Ήͤɽ੤  ຌೖͺ͕๫͢͏ͳ͞Θ͍Ε͗ͳ͑͟͡͏Ήͪ͢ɽԗ໼ ͬ͞Δ͍ͨ͞Ε͗ͳ͑͟͡͏Ήͪ͢ɽ͗Ͳͪ͘ͳ͢ͱ΍ɼҲਕ͵Δ୯Ͷ΍໐࿯͖ͥ͜Ͷम৮͢ͱಉ͏ͱศͤ͞ͳ͗ड़པΖ͹Ͳɽ‫ۅ‬࿨ɼαϱϑωώ΢φ͢͵͗Δౖ໨͢ͱͲ΍ɼΏΕͪ͏͞ͳΏΖ๏͗͏͏ͳࢧͮ
ͱ͏Ήͪ͢ɽ୉ָ͹‫ंڂݜ‬ͺ࿓ಉ࣎ؔͳ‫ۂ‬ແ಼༲Ͷଲ͢ͱമ‫͗ͤͲڇ‬ɼͨΗͲ΍ࣙ෾͹ΏΕͪ͏ࣆ͹ҟͶ༑ऴ͵ਕ͗ͨ͹ಕΝમΞͲ͏Ήͤɽ๽Ͷͳͮͱً‫ۂ‬ͺͨ͹Ԉௗͫͳࢧͮͱ͏Ήͤɽࣙ෾Ͳ௒ୣͪ͢ࣁۜͲ޹
͘͵Γ͑Ͷ‫֋ڂݜ‬൅ΝͤΖͳ͏͑қັͲͺɼ஭̏ʁԗ໼ࢱ͗ /,06 སरਫ਼ͫͮͪ࣎Ͷɼ‫౐ښ‬୉ָ͗ߨͮͱ͏Ζً‫ۂ‬ਬ਒ϕϫήϧϞ *7(3 Ͳणৈͪ͢ɽ
ͨ͹‫ى‬೨΢ϱνϑϣʖʤ/,06 ೧ๅ  S ʥ࣎Ͷۛʓً‫ͤۂ‬Ζ͞ͳΝ࿫͢ͱ͏ͪ͗ɼ৆ࡋͺً‫ۂ‬‫ٌޛ‬ಕͶ৒ͮͪΔɼͳ‫ͳͪ͞͏ͱͮݶ‬Νࢨͤɽ

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஭̑ʁ/,06 སरਫ਼ 0 ౲࣎ ͹নຌ໎ࢢɼԗ໼޼‫ل‬ɼ੤୫ைඛ̑໌͗ೖຌ‫৿ࡃܨ‬ซऀक࠷୊̕յʰ‫ۂة‬Ͷ‫֋ڂݜ‬൅͢ͱཋ͢͏າཔ͹ໂʱΠ΢υΠαϱτηφʤѬসτέόϩϋγϱηʀζϡϏϱʥ౽ਁ޽‫ۂ‬෨໵Ͳ࠹༑ऴৈΝणৈͪ͢ɽ

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+5+5‫౐ښ‬୉ָ ָࡏ༧߻‫گ‬ү‫ڂݜ‬ਬ਒ιϱνʖ݊߃ௗथऀճ͹૱߻ҫྏ֋൅ϤωρφCenter for the Promotion of Interdisciplinary Education and Research
Research and Educational Unit of Leaders for Integrated Medical System (LIMS)
http://www.lims.kyoto-u.ac.jp/