CUSTOM SERVICES

PLANTS FOR PLANTS ®

EXTRACTION, ISOLATION AND PURI
Indena Custom Services for extraction, isolation andpurification of natural derivatives include a full range ofmanufacturing capabilities for food and pharma grade
ingredients across a wide range of scales.
The combination of Indena’s expertise and state-of-the-art
facilities delivers products and processes from small scale tolarge commercial manufacturing supplies.
Indena’s R&D center is located in Italy, while the production
units are in Italy, France and India.
Indena’s facilities incorporate separated and authorized areasfor handling pharma and food grade natural derivatives andthe Quality System ensures compliance to cGMP and Hazard
Analysis and Crytical Control Points (HACCP) guidelines
respectively.

INDENA CUSTOM SERVICES FOR EXTRACTION, ISOLATION
AND PURIFICATION OF NATURAL DERIVATIVES OFFER:
Scientific research services in the field of botanicalextracts for use in the chemical, pharmaceutical, hygienicand beauty care fields.
Extraction, isolation and purification process development,
scaling-up and manufacturing
Phase-specific analytical development and validation
Control of incoming raw materials and biomasses
Characterization, certification and control of incoming
raw materials and biomasses
Agronomical development and GACP (Good AgriculturalCollection Practices) compliant cultivation of food andmedicinal plants
QC testing of in-process materials
Stability studies according to ICH guidelines
Commercial production of APIs in italian AIFA and US-FDA
inspected manufacturing sites
High containment areas
Food commercial production scale in authorized areas

FICATION OF NATURAL DERIVATIVESQUALITY MAMAGEMENT
DEDICATED QA UNITSTRAINED AND EXPERIENCED PERSONNELICH COMPLIANCE
ISO14001 ACCREDITATIONCGMP AND HACCPFEATURESSERVICESANALYTICALCAPABILITIESHAMMER AND KNIFE GRINDERSBOTANICAL R & DHPLC-RID

AGRONOMICAL R & DHPLC-DADGACP CULTIVATIONSHPLC-ELSDSTATIC AND DYNAMIC PERCOLATORSLIQUID-LIQUID EXTRACTORSREACTORS
CONCENTRATORS (ALSO THIN LAYER)

PROCESS DEV.
SCALING-UP
PROCESS VALIDATIONMANUFACTURINGSCIENTIFIC RESEARCHFILTER-PRESSSTATIC AND DYNAMIC DRYERS

ELISA
HPLC-MS
UPLC-UVUPLC-DADLARGE SCALE CHROMATOGRAPHY
CENTRIFUGESHPLC-FDOPERATIONSGRINDING
EXTRACTION
CONCENTRATION

GC-FID
GC-NPDHPTLC
TOCISOLATIONDVSMICROWAVE DRYERS

PURIFICATION

TG/DTAATOMIZERSCRYSTALLIZATIONDSCDRYINGSUNTEST

WEIGHING

BIOANALYZER

PACKAGINGMICROSCOPY

CHROMATOGRAPHYPPSLSEMISYNTHESISXRPDMILLS AND SIEVESMIXERSHIGH CONTAINMENT AREAS
EQUIPPED WITH GLOVE BOXES

Indena S.p.A. is the world’s leading company dedicated to theresearch, development and production of active principles
derived from natural sources.
With its capabilities and expertise, Indena covers foodsupplements and pharmaceutical areas, producing bulks ofactive ingredients under cGMP guidelines in AIFA and FDAapproved environment, starting from biomasses obtained
according to GACP guidelines.
Today Indena opens its facilities for custom services, sharing
with customers its innovative research and production
capabilities at lab, kilo-lab and industrial scale, also in thefield of Highly Potent Active Ingredients (HPAIs).

DPR0157 - 03/2011*11/2016

More than Ninety years of Indena presence in thepharmaceutical market are a guarantee of high quality
standards and reliability, that just a few companies in theworld can claim.
Indena is a private Italian company based in Milan (Italy);
it employs more than 800 staff distributed on 1 R&DCentre, 5 production sites and 5 international branches
throughout the world and manages sales in more than 70countries.

CONTACT US
Indena S.p.A.
Viale Ortles, 1220139 Milano, Italy
Indena.com