MILLILITER VOLUME MICRO REACTOR
User Manual - Version 1.0

Visiting address Colosseum 15  7521 PV Enschede Postal address P.O. Box 214  7500 AE Enschede  The Netherlands
Phone +31 53 850 6 850 Fax +31 53 850 6 851 E-mail info@micronit.com Internet www.micronit.com

CONTENTS
CONTENTS ............................................................................................................... 2
1

INTRODUCTION ............................................................................................. 3

2

ASSEMBLY AND ADJUSTMENTS................................................................. 4
2.1
2.2
2.3

3

Step 1: Parts check ...................................................................................... 4
Step 2: Assembly of the Frame .................................................................... 4
Step 3: Assemble fluidic connections............................................................ 5
MR_TF_KIT..................................................................................................... 63.1
Assembly of the connections ........................................................................ 63.1.1
Notes ................................................................................................. 7
4

SPECIFICATIONS........................................................................................... 84.14.2

v1.0

MR_FRAME_1507 ....................................................................................... 8
MR_TF_KIT (optional).................................................................................. 8

User Manual - MR_FRAME_1507

2

1INTRODUCTION

This manual describes the use of the Micro Reactor Connection Frame 1507. The
MR_FRAME_1507 is designed for all glass Micro reactor type MR_1507.4_xxx.xx.
The frame has five 1/4-28 threaded fluidic connection positions. The fluidic
connections can be made using the Micronit MR_TF_KIT, also described in thismanual, to create an user friendly interface.
The MR_FRAME_1507 is designed with a large viewing window to allow fullinspection of the Micro reactor. All fluidic connections are placed on one side of theMicro reactor.
The MR_FRAME_1507 has two O-rings which allows the user to clamp themicroreactor inside the frame without the use of fluidic connections.

Key features of MR_FRAME_1507:•••

Easy Micro reactor replacement
Chemically inert holder (Hastelloy C4)
Full optical inspection area for the glass reactor

Key features of MR_TF_KIT:

••
•

v1.0

User friendly, leak-free microfluidic connections
Easy to assemble connection set
Connections are protected against over tightening

User Manual - MR_FRAME_1507

32ASSEMBLY AND ADJUSTMENTS

In this section, the assembly of the MR_FRAME_1507 will be explained step by step.

2.1

STEP 1: PARTS CHECKCheck if all the parts are included, see figure 2.1.
4b4a5126
34b4aFigure 2.1. All the parts of the MR_FRAME_1507.

Part list MR_FRAME_1507
1.
2.
3.
4.

5.
6.

2.2

Frame top (Hastelloy C4)
Frame bottom (Hastelloy C4)
Protection frame (blue anodized Aluminium)
Screw seta.
2x M4x8 CSK
b.
4x M4x10 CSK
Hex key (2.5)
Viton® O-rings (2x )STEP 2: ASSEMBLY OF THE FRAME

The MR_FRAME_1507 is shipped clean, but additional cleaning (e.g. with IPA orAcetone) is advised before assembly of the parts.
The Frame bottom can be fixed onto the Protection frame using the two M4x8 CSKscrews, see figure 2.2.

Figure 2.2. Frame bottom assembled on Protection frame.

v1.0

User Manual - MR_FRAME_1507

4

The Frame top has cut-outs to fit the two o-rings (not wetted) which clamp the Microreactor into the frame if desired, see figure 3. If the o-rings are not used, the Microreactor can be removed and placed easily in the frame, without disconnecting theFrame top. The Micro reactor is not clamped in the latter case if no fluidic connections
are assembled into the frame.

Figure 2.3a. Place the O-rings in the recesses on
the bottom side of the Frame top.

Figure 2.3b. O-rings inside assembled frame(see yellow arrows).

The Frame top can be fixed onto the Frame bottom using the four M4x10 CSK screws.

Figure 2.4. MR_FRAME_1507 with Micro reactor MR_1507.4_MRQ.01 assembled.

2.3

STEP 3: ASSEMBLE FLUIDIC CONNECTIONSThe MR_FRAME_1507 is preferably used in combination with the Micronit Fluidicconnections (MR_TF_KIT), see chapter 3.

v1.0

User Manual - MR_FRAME_1507

53MR_TF_KITThe MR_TF_KIT is a set of microfluidic connections using 1/8” tubing and 1/4-28 UNF
threaded fittings. The PEEK fittings are specially designed to avoid over tightening ofthe fluidic connections.

3.1

ASSEMBLY OF THE CONNECTIONSThe MR_KIT includes approximately 1.5m of ETFE tube (OD=1/8”, ID=0.062”), a setof 5 PEEK nuts, 5 ferrule assemblies (PEEK ferrule with stainless steel lock-ring), aPEEK assembly union and an ETFE Plug. For the assembly of a fluidic connection
you will need the ETFE tube, a nut and a ferrule assembly and the union.
The first step is to cut the ETFE tube to the desired length. The tube is easy to cut, but
a sharp knife is advised for a clean cut, see figure 3.1. After the tube is cut it shouldlook similar to the tube end in figure 3.2.

Figure 3.1, ETFE tube cut to length.

Figure 3.2, ETFE tube end after it is cut.

The nut and ferrule assembly can now be assembled onto the tube. Micronit uses
fittings which are protected against over tightening. For the ferrule assembly it isimportant to make sure the stainless steel lock-ring has its flared side directed to theferrule, see figure 3.3 and 3.4. The straight end fits partially into the nut.

Figure 3.3, Nut and ferrule set; left) parts viewed from above, right) parts viewed from below.

v1.0

User Manual - MR_FRAME_1507

6Figure 3.4, parts placed around the tube.

When assembled correctly, place the tube end in the union and tighten the nut byhand. During the tightening keep the tube pressed into the union, such that the ferrule
is assembled flush to the tube, see figure 3.5. When sufficiently tightened the nut
makes a clicking sound.

Figure 3.5, Tighten the nut by hand in the union and check the result.

On the free end of the tube you can connect other connections, to make the fluidic
connection with for instance a syringe pump or other equipment.
The connection is now ready to use!

Figure 3.6, Properly assembled microfluidic connection.

3.1.1
-v1.0

NOTES
Tightening any fluidic connection type should be done with care !
Whenever a connection is damaged, replace it to avoid leakage in your system

User Manual - MR_FRAME_1507

7

4SPECIFICATIONS

4.1

MR_FRAME_1507

Reactor Holder (top and bottom)

•••••

4.2

Material holder
Material protection plate
O-rings (not wetted)
Overall dimensions (l × w × h)
Number of fluidic connections: Hastelloy C4: Anodized Aluminium: Viton®
: 170 × 90 × 15 mm:5

MR_TF_KIT (OPTIONAL)

MR_TF_KIT••••

Dimensions capillaries
Material capillaries
Material nuts
Material fittings: 1/8” OD, 1/16” ID, length 5ft: ETFE (Tefzel): PEEK (PolyEtherEtherKetone): PEEK (seals) / stainless steel (rings)

Contact
Micronit Microfluidics
Postbus 214
7500 AE Enschede
The Netherlands +31 53 850 6 850
 +31 53 850 6 851
 info@micronit.com
www.micronit.com

v1.0

User Manual - MR_FRAME_1507

8