日本組織培養学会 第 85 回大会（京都府京都市)

会期：平成 24 年 5 月 17 日（木）・18 日（金）
会場：京都大学百周年時計台記念館〒606-8501 京都市左京区吉田本町

大会長：浅香 勲
京都大学 iPS 細胞研究所規制科学部門
TEL：075-366-7059 FAX：075-366-7078
e-mail: jtca85@cira.kyoto-u.ac.jpᄢળෳട⠪߳ߩߏ᩺ౝ
㧝㧚

ᄢળળ႐
ળ႐㧦੩ㇺᄢቇ⊖๟ᐕᤨ⸘บ⸥ᔨ㙚‫ޥ‬੩ㇺᏒᏀ੩඙ศ↰ᧄ↸
JVVRYYYM[QVQWCELRLCENQEMVQYGT


㧞㧚

ᄢળᣣ⒟

 ᣣ⋡ ᦬  ᣣ ᧁᦐᣣ 

 ᣣ⋡

ฃઃ㐿ᆎ
㐿ળ᜿ᜦᅑബ⾨ኻ⽎Ṷ㗴

৻⥸Ṷ㗴 Σ ‫ޠ♽ࠗ࠮࠶ࠕ‛⮎ޟ‬

৻⥸Ṷ㗴 Τ ‫ޟ‬ౝ⢦⪲♽⚦⢩‫ޠ‬

৻⥸Ṷ㗴 Υ ‫ޟ‬ౣ↢කᎿቇ‫ޠ‬

౏㐿ၭ㙃ᜰዉ჻㙃ᚑ⻠⠌ળ㧔╙  ࿁㧕

ࠪࡦࡐࠫ࠙ࡓ㧝‫ޟ‬ታ⃻ൻ⋡೨ߩᐙ⚦⢩ᴦ≮ߣၭ㙃ᛛⴚ‫ޠ‬ᙣⷫળ ᦬  ᣣ ㊄ᦐᣣ 

ฃઃ㐿ᆎ



৻⥸Ṷ㗴 Φ ‫ޟ‬ᄙ⢻ᕈᐙ⚦⢩‫ޠ‬

5GUUKQPKP'PINKUJ✚ળ ࡎ࡯࡞



․೎⻠Ṷ‫ޟ‬K25 ⚦⢩⎇ⓥߩㅴዷ‫ޠ‬

ࠪࡦࡐࠫ࠙ࡓ‫⚦ޟ‬⢩ធ⌕ߣ⚦⢩ᯏ⢻೙ᓮߩᦨవ┵‫ޠ‬ 

㐽ળߩㄉ


㧟㧚

․೎⻠Ṷ‫ޔࡓ࠙ࠫࡐࡦࠪޔ‬ၭ㙃ᜰዉ჻㙃ᚑ⻠⠌ળ․೎⻠Ṷ ‫ޟ‬K25 ⚦⢩⎇ⓥߩㅴዷ‫ޠ‬







㧔 ᣣ⋡㧕ࠪࡦࡐࠫ࠙ࡓ㧝‫ޟ‬ታ⃻ൻ⋡೨ߩᐙ⚦⢩ᴦ≮ߣၭ㙃ᛛⴚ‫ޠ‬㧔 ᣣ⋡㧕․೎⻠Ꮷ ጊਛ િᒎ㧔ᐳ㐳㋈ᧁ ፏᒾ㧕 ࠝ࡯ࠟ࠽ࠗࠩ࡯ ਛ᧛ ᐘᄦ
5

࠯ࡁࡈ࡝࡯ࡅ࠻ '5K25 ⚦⢩ߩၭ㙃ࠪࠬ࠹ࡓߩ⏕┙㒙ਭᵤ ⧷ᙗ

5

K25 ⚦⢩ߩ቟ోᕈߦኻߔࠆข⚵ߺ㜞ᯅ ๺೑

5

⥄ኅ⚦⢩ࠍ↪޿ߚౣ↢ක≮⵾ຠߩຠ⾰▤ℂ⇗ ⾫৻㇢

5

ਇᱫൻ⿒ⴊ⃿೨㚟⚦⢩ᩣ߆ࠄߩ⿒ⴊ⃿ߩੱᎿ↢↥ᩙ↰ ⦟‫ޔ‬ਛ᧛ ᐘᄦ

5

K25 ⚦⢩ߩ✂⤑∔ᖚ߳ߩᔕ↪㜞ᯅ ᡽ઍ

ࠪࡦࡐࠫ࠙ࡓ㧞‫⚦ޟ‬⢩ធ⌕ߣ⚦⢩ᯏ⢻೙ᓮߩᦨవ┵‫ޠ‬㧔 ᣣ⋡㧕ࠝ࡯ࠟ࠽ࠗࠩ࡯࡮ᐳ㐳㧦 ⛗㊁ᴛ િ‫ ☯ޔ‬ᤘ⧞
5

ᒻᘒ೙ᓮ߇ਈ߃ࠆᯏ⢻㕙ߩᄌൻ ⢄⚦⢩ೋઍၭ㙃ߩ⚻㛎߆ࠄ⛗㊁ᴛ િ

5

⚦⢩ᴦ≮ࠍഥߌࠆൻว‛਄᧖ ᔒᚑ

5

⚦⢩ᄖࡑ࠻࡝࠶ࠢࠬߩᄙ᭽ᕈߣ࠹࡯࡜࡯ࡔࠗ࠼ၭ㙃ၮ᧚5

ᄙ⢻ᕈᐙ⚦⢩ߩಽൻࠍࠨࡐ࡯࠻ߔࠆ⚦⢩ᄖⅣႺ㑐ญ ᷡବ☯ ᤘ⧞
ၭ㙃ᜰዉ჻㙃ᚑ⻠⠌ળ㧔╙  ࿁㧕ડ↹㧦ᣣᧄ⚵❱ၭ㙃ቇળᢎ⢒⎇ⓥࠪࠬ࠹ࡓᆔຬળ ᐳ㐳㧦ฎᳯᬮ↰ ⟤଻96㧔㧝㧕ၭ㙃ၮ⋚ᛛⴚࠦ࡯ࠬ᭎ⷐߦߟ޿ߡߩ⺑᣿ ฎᳯ㧙ᬮ↰ ⟤଻㧔㧞㧕ၭ㙃ၮ⋚ᛛⴚࠦ࡯ࠬ +++ ߣ⚦⢩ၭ㙃჻⹺ቯߦߟ޿ߡߩ᭎ⷐ⺑᣿ 㧔㧟㧕ၭ㙃ၮ⋚ᛛⴚࠦ࡯ࠬ ++ ᵈᗧὐ ᳞߼ࠄࠇࠆᛛⴚ ㋈ᧁ ፏᒾ
਄↰ ᔘ૫
㧔㧠㧕ၭ㙃ၮ⋚ᛛⴚࠦ࡯ࠬ + ᵈᗧὐ ᳞߼ࠄࠇࠆᛛⴚ 㑆ਛ ⎇৻

㧔㧡㧕ၭ㙃ၮ⋚ᛛⴚࠦ࡯ࠬ +++ၭ㙃ᜰዉ჻⸽ ᝼ਈߣ⾗ᩰ⠪ߩ౏⴫㋈ᧁ ፏᒾ‫ޔ‬ฎᳯ㧙ᬮ↰⟤଻㧠㧚Ṷ⠪ߩ⊝᭽߳
⻠Ṷߩࡊ࡟࠯ࡦ࠹࡯࡚ࠪࡦߪోߡ 2% ᶧ᥏ࡊࡠࠫࠚࠢ࠲࡯㧔 บ㧕ߦࠃࠆญ㗡⊒⴫ߣߒ߹ߔ‫ޕ‬

߹ߚᅑബ⾨⻠Ṷߪߎࠇߦട߃ߡࡐࠬ࠲࡯ឝ␜ࠍ߅㗿޿ߒ߹ߔ‫ޕ‬ญ㗡⊒⴫ߦ߅޿ߡߪ 9KPFQYU
㧔:2‫ޔ‬8KUVC‫ޔ‬㧣㧕 ߹ߚߪ /CE

ߩ /KETQUQHV2QYGT2QKPVߢේⓂࠍ૞ᚑߒታ౮ߏ⏕⹺ߩ਄‫ޔ‬%&41/ ޽ࠆ޿ߪ 75$ ࡈ࡜࠶ࠪࡘࡔࡕ࡝࡯ߦ⸥㍳ߒߡ߅ᜬߜߊߛߐ޿‫ޕ‬ේⓂ࠺࡯࠲ߪߏ⻠Ṷ࡮ߏ⊒⴫ߩ  ಽ೨߹ߢߦ‫⊖ޔ‬๟ᐕ⸥ᔨࡎ࡯࡞ᮮߩࠬ࡜ࠗ࠼ฃઃߢ⹜౮ࠍߒߡᜂᒰ⠪ߦ߅ᷰߒߊߛߐ޿‫ޕ‬ේⓂࠍળ႐↪ࠦࡦࡇࡘ࡯࠲ߦࠦࡇ࡯ߒ߹ߔ‫ޕ‬ᄢળ⚳ੌᓟߪ‫ޔ‬ේⓂߪᄢળߩ⽿છߦ߅޿ߡ೥㒰޿ߚߒ߹ߔ‫ޔ߅ߥޕ‬ේⓂߦേ↹‫․ઁߩߘޔ‬ᱶലᨐࠍ฽߻႐ว‫࠲࡯࠺ߪߊߒ߽ޔ‬ߩࠦࡇ࡯ࠍᦸ߹ࠇߥ޿႐วߪ 2% ࠍߏᜬෳߩ਄‫⴫⊒ޔ‬ථ߆ࠄߏ⥄りߢᠲ૞ࠍ߅㗿޿⥌ߒ߹ߔ㧔ធ⛯ߦ  ಽ߶ߤᤨ㑆ࠍ૶޿߹ߔ‫⻠ߏޕ‬Ṷᤨ㑆ߦ฽߹ࠇ߹ߔߩߢߏᵈᗧߊߛߐ޿㧕‫ࡓ࡞ࠖࡈޕ‬ࠬ࡜ࠗ࠼ߩᤋ౮ߪⴕ޿߹ߖࠎ‫ޕ‬ฦ⊒⴫ᤨ㑆ߪᄢળࡊࡠࠣ࡜ࡓߦߡߏ⏕⹺ߊߛߐ޿‫ޕ‬ౝ  ಽ⒟ᐲ߇⾰໧⸛⺰ᤨ㑆ߣߥࠅ߹ߔ‫ޕ‬ᤨ㑆ౝߢߩߏ⻠Ṷ࡮ߏ⊒⴫ߦߏදജߊߛߐ޿‫ޕ‬㧡㧚ᅑബ⾨ኻ⽎Ṷ㗴ߩ⊒⴫ߣክᩏ
ᅑബ⾨ኻ⽎Ṷ㗴ߩ⊒⴫ߪ‫ޔ‬ญṶ㧔⊖๟ᐕ⸥ᔨࡎ࡯࡞㧕ߣ‫࡯࠲ࠬࡐޔ‬ឝ␜㧔 㓏࿖㓙੤ᵹࡎ࡯࡞㧕ߦߡⴕߞߡ޿ߚߛ߈߹ߔ‫ޕ‬ญṶߪ  ᣣ⋡  ߆ࠄߩ㐿ᆎߣߥࠅ߹ߔ‫ߩ࡯࠲ࠬࡐޕ‬ឝ␜ࠍ  ᣣ⋡ඦ೨ 㨪 ᣣ⋡ᱜඦ߹ߢⴕߞߡߊߛߐ޿‫ߪ࠭ࠗࠨ࡞ࡀࡄޕ‬᏷ EO‫ޔ‬㜞ߐ EO ߢߔ‫࡯࠲ࠬࡐޕ‬਄ㇱߦ‫ޔ‬Ṷ㗴‫⴫⊒ޔ‬⠪ฬ‫ޔ‬ᚲዻࠍ⴫␜ߒ‫⴫⊒ޔ‬⠪ߩᏀ⢋ߦ٤ශࠍઃߌߡߊߛߐ
޿‫ޕ‬ቇળᅑബ⾨ㆬቯ೙ᐲߦၮߠ߈‫ޔ‬ᣣᧄ⚵❱ၭ㙃ቇળᐙ੐߇ฃ⾨⠪ࠍ᳿ቯߒ߹ߔ‫ޕ‬ฃ⾨⠪⊒
⴫ߪ  ᣣ⋡ߩ✚ળߢⴕ޿߹ߔߩߢ‫ߚࠇߐࠍ⴫⊒ޔ‬ᣇߪᔅߕ✚ળߦߏ಴Ꮸߊߛߐ޿‫ޕ‬ฃ⾨⠪ߦߪ⾨⁁ਗ߮ߦ೽⾨㧔⾨㊄㧕߇᝼ਈߐࠇ߹ߔ‫ޔ߅ߥޕ‬ฃ⾨⠪ߪԘળຬㅢା߳‫ޟ‬ฃ⾨ߩᗵᗐ‫ޠ‬
ࠍነⓂߔࠆ‫ޔ‬ԙฃ⾨㗴ฬߦࠃࠆේ⪺⺰ᢥࠍ  ᐕએౝߦᧄቇળᯏ㑐⹹㧔6%4%㧕߳ᛩⓂߔࠆ‫ߥޔ‬ߤߩቇળᵴേ߳ߩߏදജࠍࠃࠈߒߊ߅㗿޿⥌ߒ߹ߔ‫ޕ‬

㧢㧚

✚ળ
✚ળߪ‫  ᦬ ޔ‬ᣣ ㊄  ߆ࠄ  ߢߔ‫ޕ‬ᐙ੐࡮ฦ⒳ᆔຬળᆔຬ㐳ߩ಴Ꮸࠍ߅㗿޿⥌ߒ߹ߔ‫ޕ‬ฦ⒳ႎ๔‫ޔ‬ክ⼏࡮᳿⼏╬ߩ⼏੐ࠍ੍ቯߒߡ޿߹ߔ‫ޔߚ߹ޕ‬ᅑബ⾨ฃ⾨⠪ߩ⊒⴫ࠍⴕ޿߹ߔ‫ޕ‬㧣㧚⊓㍳࡮ෳട⾌ߥߤㇷଢᝄᦧญᐳ ญᐳ⇟ภ㧦
ญᐳฬ⒓㧦ᣣᧄ⚵❱ၭ㙃ቇળ╙  ࿁ᄢળታⴕᆔຬળᐔᚑ  ᐕ  ᦬  ᣣ߹ߢߦ੐೨⊓㍳ᡰᛄࠍߐࠇ߹ߔߣഀᒁߦߥࠅ߹ߔ‫ޕ‬ᄢળࡎ࡯ࡓࡍ࡯ࠫ
ߩᝄㄟ↪⚕ࠍߏෳᾖߊߛߐ޿‫ޕ‬ᄢળෳട⸽‫ޔ‬ᙣⷫળෳട⸽ߪ‫ޔ‬ᒰᣣߩળ႐ฃઃߦߡ߅ᚻᷰߒ
޿ߚߒ߹ߔ‫ޕ‬ߥ߅‫ޔ‬ᣣᧄേ‛ታ㛎ઍᦧᴺቇળߩળຬߩ⊝᭽ߦ߽ᧄળ‫ޔ‬ᙣⷫળ߳৻⥸ળຬ࡮ቇ↢ળຬߣߒߡߏෳട޿ߚߛߌ߹ߔ‫ޕ‬





ળຬ⒳೎

ᄢળෳട⾌

ᙣⷫળ⾌੐೨⊓㍳ߩ႐ว

৻⥸ળຬ

6,000 ౞4,000 ౞ቇ↢ળຬ3,000 ౞3,000 ౞㕖 ળ ຬ

7,000 ౞5,000 ౞ቇ↢㕖ળຬ4,000 ౞4,000 ౞ᒰᣣ⊓㍳ߩ႐ว

৻⥸ળຬ

7,000 ౞5,000 ౞ቇ↢ળຬ4,000 ౞4,000 ౞㕖 ળ ຬ

8,000 ౞6,000 ౞ቇ↢㕖ળຬ5,000 ౞5,000 ౞ฬ⹷ળຬో㗵ήᢱ㧔ෳട⸽ࠍㅍઃ⥌ߒ߹ߔ㧕

 
㧤㧚

ᙣⷫળ
ᙣⷫળߪ‫ ޔ‬ᣣ㧔ᧁ㧕 ߆ࠄ‫ޟ‬࿖㓙੤ᵹࡎ࡯࡞‫ޕߔ߹޿ⴕߡߦޠ‬㧥㧚ડᬺዷ␜ߦߟ޿ߡ
ડᬺዷ␜ࠍ੩ㇺᄢቇ⊖๟ᐕᤨ⸘บ⸥ᔨ㙚  㓏㧘࿖㓙੤ᵹࡎ࡯࡞ߦߡⴕ޿߹ߔ‫ޕ‬ᤚ㕖߅┙ߜነࠅߊߛߐ޿‫ޕ‬㧝㧜㧚 ᐙ੐ળ ᦬  ᣣ ᳓ ᄕೞߦ੍ቯߒ߹ߔ‫߇⚦⹦ޕ‬᳿߹ࠅ߹ߒߚࠄᐙ੐ᓎຬߩ⊝᭽߳ࡔ࡯࡞ߦߡ߅⍮ࠄߖߒ߹ߔ‫ޕ‬㧝㧝㧚 ળ႐᩺ౝ
ᄢળળ႐





ᙣⷫળ߅ࠃ߮ડᬺዷ␜ળ႐

੩ㇺᄢቇ⊖๟ᐕᤨ⸘บ⸥ᔨ㙚⊖๟ᐕ⸥ᔨࡎ࡯࡞
੩ㇺᄢቇ⊖๟ᐕᤨ⸘บ⸥ᔨ㙚࿖㓙੤ᵹࡎ࡯࡞

੩ㇺᄢቇ⊖๟ᐕᤨ⸘บ⸥ᔨ㙚㧝㓏ࠬ࡜ࠗ࠼ฃઃ
ญṶળ႐

ෳടฃઃ


੩ㇺᄢቇ⊖๟ᐕᤨ⸘บ⸥ᔨ㙚㧞㓏ᄢળ੐ോዪ

ડᬺዷ␜࡮ᙣⷫળ႐
ᅑബ⾨ࡐࠬ࠲࡯

੩ㇺᄢቇศ↰ࠠࡖࡦࡄࠬ੩ㇺᄢቇศ↰ࠠࡖࡦࡄࠬ߳ߩ੤ㅢਥⷐ㋕㆏㚞㩷㪡㪩䋯ㄭ㋕㩷
੩ㇺ㚞䈎䉌㩷

೑↪੤ㅢ

ਸ਼ゞ㩷

Ꮢ䊋䉴♽

ᯏ㑐╬㩷

䊋䉴஗㩷

⛔㩷

Ꮢ䊋䉴㩷

੩ㇺ㚞೨㩷

㒋ᕆ㩷
Ꮢ䊋䉴㩷
ᴡේ↸㚞䈎䉌㩷

࿾ਅ㋕ὖਣ
✢㩷
ὖਣ੹಴Ꮉ
㚞䈎䉌㩷
࿾ਅ㋕᧲⷏
✢㩷
᧲ጊ㚞䈎䉌㩷

੩㒋㩷
಴↸ᩉ㩷

Ꮢ䊋䉴㩷

Ꮢ䊋䉴㩷

྾᧦ᴡේ
↸㩷

ὖਣ੹಴
Ꮉ㩷

᧲ጊਃ᧦㩷

ᓤᱠ㩷

䋨᧲䈻䋩㩷

Ꮢ䊋䉴㩷

಴↸ᩉ㚞
೨㩷

Ꮢ䊋䉴⚻〝㩷

ᧄቇ䉁䈪䈱
ᚲⷐᤨ㑆㩷

㪈㪎 ♽⛔㩷

䇸᧲ጊㅢ㩷 ർᄢ〝䊋䉴䉺䊷䊚䊅䊦䇹ⴕ㩷䇸ᴡේ↸ㅢ㩷 ㍪ᨋゞᐶ䇹ⴕ㩷㪉㪇㪈 ♽⛔㩷䇸␧࿦㩷 ⊖ਁㆉ䇹ⴕ㩷⚂ 㪉㪌 ಽ㩷㪊㪈 ♽⛔㩷

䇸᧲ጊㅢ㩷 㜞㊁䊶ጤୖ䇹ⴕ㩷⚂ 㪉㪌 ಽ㩷㪈㪎 ♽⛔㩷㪊 ♽⛔㩷㪉㪇㪊 ♽⛔㩷䇸ᴡේ↸ㅢ㩷 ㍪ᨋゞᐶ䇹ⴕ㩷䇸⊖ਁㆉ㩷 ർ⊕Ꮉ઀ફ↸䇹ⴕ㩷䇸㌁㑑ኹ㆏䊶㍪ᨋゞᐶ䇹ⴕ㩷⚂ 㪉㪌 ಽ㩷⚂ 㪉㪌 ಽ㩷⚂ 㪈㪌 ಽ㩷㪉㪇㪈 ♽⛔㩷䇸⊖ਁㆉ䊶␧࿦䇹ⴕ㩷⚂ 㪈㪌 ಽ㩷㪉㪇㪍 ♽⛔㩷

䇸㜞㊁㩷 ජᧄർᄢ〝䇹ⴕ㩷⚂ 㪉㪇 ಽ㩷㪉㪇㪈 ♽⛔㩷䇸⊖ਁㆉ㩷 ජᧄ੹಴Ꮉ䇹ⴕ㩷⚂ 㪉㪇 ಽ㩷㪊㪈 ♽⛔㩷

䇸ୃቇ㒮䊶ጤୖ䇹ⴕ㩷⚂ 㪉㪇 ಽ㩷㪉㪇㪈 ♽⛔㩷䇸␧࿦㩷 䉂䈹䇹ⴕ㩷⚂ 㪈㪇 ಽ㩷㪈㪎 ♽⛔㩷

䇸㍪ᨋゞᐶ䇹ⴕ㩷⚂ 㪈㪇 ಽ㩷㪉㪇㪍 ♽⛔㩷⚂ 㪊㪌 ಽ㩷⚂ 㪊㪌 ಽ㩷⚂ 㪉㪇 ಽ㩷ਅゞ䊋䉴஗㩷੩ᄢᱜ㐷೨෶䈲⊖ਁㆉ㩷⊖ਁㆉ㩷੩ᄢᱜ㐷೨෶䈲⊖ਁㆉ㩷੩ᄢᱜ㐷೨෶䈲⊖ਁㆉ㩷
⊖ਁㆉ㩷
⊖ਁㆉ㩷
⊖ਁㆉ㩷
⊖ਁㆉ෶䈲
੩ᄢᱜ㐷೨㩷੩ᄢᱜ㐷೨෶䈲⊖ਁㆉ㩷੩ᄢᱜ㐷೨෶䈲⊖ਁㆉ㩷੩ᄢᱜ㐷೨෶䈲⊖ਁㆉ㩷⊖ਁㆉ෶䈲੩ᄢᱜ㐷೨㩷⊖ਁㆉ㩷㧝㧞㧚 ᄢળߦߟ޿ߡߩ߅໧޿วࠊߖ
ᣣᧄ⚵❱ၭ㙃ቇળ╙  ࿁ᄢળታⴕᆔຬળ
੩ㇺᄢቇ K25 ⚦⢩⎇ⓥᚲ ⷙ೙⑼ቇㇱ㐷ౝ ‫ ޥ‬੩ㇺᏒᏀ੩඙⡛⼔㒮Ꮉේ↸ 
6'. (#:GOCKN㧦LVEC"EKTCM[QVQWCELRᣣᧄ⚵❱ၭ㙃ቇળߩࡎ࡯ࡓࡍ࡯ࠫ㧦JVVRLVECWOKPLR╙  ࿁ᄢળࡎ࡯ࡓࡍ࡯ࠫ㧦JVVRLVECWOKPLROGGV[KPFGZJVONᣣ㩷 ⒟㩷 ⴫㩷
㩷
㩷

㩷

㩷

㩷

㩷
䋵᦬䋱䋷ᣣ䋨ᧁ䋩㩷䋵᦬䋱䋸ᣣ䋨㊄䋩㩷䋹䋺䋰䋰㩷 ฃઃ㐿ᆎ㩷䋹䋺䋰䋰䋹䋺䋳䋰㩷 㐿ળ᜿ᜦ㩷

䋹䋺䋳䋰
৻⥸Ṷ㗴㩷

䋹䋺䋳䋵㩷 ᅑബ⾨ኻ⽎Ṷ㗴㩷㸊㩷 ᄙ⢻ᕈᐙ⚦⢩㩷䋱䋰䋺䋰䋰㩷 ৻⥸Ṷ㗴㩷㸇㩷 ⮎‛䉝䉾䉶䉟♽㩷䋱䋱䋺䋰䋰㪪㪼㫊㫊㫀㫆㫅㩷㫀㫅㩷㪜㫅㪾㫃㫀㫊㪿㩷䋱䋲䋺䋰䋰ᤤ㩷 ભ㩷 䉂㩷䋱䋲䋺䋳䋰㩷 ᤤ㩷 ભ㩷 䉂㩷

䋱䋳䋺䋰䋰

✚㩷 ળ㩷

䋱䋳䋺䋳䋰㩷 ၭ㙃ᜰዉ჻㙃ᚑ⻠⠌ળ㩷

䋱䋴䋺䋰䋰

․೎⻠Ṷ㩷

䋱䋴䋺䋳䋰㩷 䋨╙ 㪋 ࿁䋩㩷䋱䋵䋺䋰䋰䇸㫀㪧㪪 ⚦⢩⎇ⓥ䈱ㅴዷ䇹㩷䋱䋴䋺䋴䋰㩷 䉲䊮䊘䉳䉡䊛䋱㩷䋱䋵䋺䋱䋰䉲䊮䊘䉳䉡䊛䋲㩷 㩷㸈㩷 ౝ⢦⪲♽⚦⢩㩷㸉㩷 ౣ↢කᎿቇ㩷㩷 䇸ታ⃻ൻ⋡೨䈱ᐙ⚦⢩ᴦ≮䈫㩷䋱䋷䋺䋳䋵㩷

ၭ㙃ᛛⴚ䇹㩷

䋱䋸䋺䋰䋰㩷 ᙣ㩷 ⷫ㩷 ળ㩷
㩷

ฃઃ㐿ᆎ㩷

䇸⚦⢩ធ⌕䈫⚦⢩ᯏ⢻೙ᓮ䈱㩷
䋱䋷䋺䋳䋰

ᦨవ┵䇹㩷

䋱䋷䋺䋳䋰

㐽ળ䈱ㄉ㩷

ᣣᧄ⚵❱ၭ㙃ቇળ╙㧤㧡࿁ᄢળ ታⴕᆔຬ ࠪࡦࡐࠫ࠙ࡓࠝ࡯ࠟ࠽ࠗࠩ࡯࡮ᐳ㐳ታⴕᆔຬ
㋈ᧁ ፏᒾ㧔᧲੩ᄢቇᄢቇ㒮කቇ♽⎇ⓥ⑼㒝ዻ∔ᖚ↢๮Ꮏቇ࠮ࡦ࠲࡯㧕દ⮮ ਂᵗ㧔ᩣᑼળ␠⚦⢩⑼ቇ⎇ⓥᚲ㧕⛗㊁ᴛ િ㧔࿖┙ᚑ⢒ක≮⎇ⓥ࠮ࡦ࠲࡯⥃ᐥ⎇ⓥ࠮ࡦ࠲࡯వ┵ක≮㐿⊒ቶ㧕☯ ᤘ⧞㧔ᾢᧄᄢቇ ⊒↢කቇ⎇ⓥᚲ㧕ዊේ ᦭ᒄ㧔⁛┙ⴕ᡽ᴺੱ ක⮎ၮ⋚⎇ⓥᚲ 㔍∛࡮∔ᖚ⾗Ḯ⎇ⓥㇱ࡮ၭ㙃⾗Ḯ⎇ⓥቶ㧕ဈ㊁ ବብ㧔ᩣᑼળ␠ࡑࡦ࠳ࡓ ਛᄩ⎇ⓥᚲ㧕૒⮮ రା㧔 ⽷ ࡅࡘ࡯ࡑࡦࠨࠗࠛࡦࠬᝄ⥝⽷࿅ ࡅࡘ࡯ࡑࡦࠨࠗࠛࡦࠬ⎇ⓥ⾗Ḯࡃࡦࠢ㧕ਛ᧛ ᐘᄦ㧔ℂൻቇ⎇ⓥᚲࡃࠗࠝ࡝࠰࡯ࠬ࠮ࡦ࠲࡯ ⚦⢩᧚ᢱ㐿⊒ቶ㧕⮮੗ ਁ♿ሶ㧔ᗲ⍮⋵߇ࠎ࠮ࡦ࠲࡯ ਛᄩ∛㒮࡮⎇ⓥᚲ ಽሶ⣲≌ቇㇱ㧕㑆ਛ ⎇৻㧔₡දක⑼ᄢቇ ࿖㓙ᢎ⢒⎇ⓥᣉ⸳㧕ጊᧄ ⋥᮸㧔⮮↰଻ஜⴡ↢ᄢቇ౒ห೑↪⎇ⓥᣉ⸳ ಽሶ↢‛ቇ࡮⚵❱ൻቇ㧕․೎⻠Ṷ ᐳ㐳
㋈ᧁ ፏᒾ㧔᧲੩ᄢቇᄢቇ㒮කቇ♽⎇ⓥ⑼㒝ዻ∔ᖚ↢๮Ꮏቇ࠮ࡦ࠲࡯㧕ࠪࡦࡐࠫ࠙ࡓࠝ࡯ࠟ࠽ࠗࠩ࡯ ᐳ㐳ࠪࡦࡐࠫ࠙ࡓ㧝 ਛ᧛ ᐘᄦ㧔ℂൻቇ⎇ⓥᚲࡃࠗࠝ࡝࠰࡯ࠬ࠮ࡦ࠲࡯ ⚦⢩᧚ᢱ㐿⊒ቶ㧕ࠪࡦࡐࠫ࠙ࡓ㧞 ⛗㊁ᴛ િ㧔࿖┙ᚑ⢒ක≮⎇ⓥ࠮ࡦ࠲࡯⥃ᐥ⎇ⓥ࠮ࡦ࠲࡯వ┵ක≮㐿⊒ቶ㧕☯ ᤘ⧞㧔ᾢᧄᄢቇ ⊒↢කቇ⎇ⓥᚲ㧕ၭ㙃ᜰዉ჻㙃ᚑ⻠⠌ળ࡮5GUUKQPKP'PINKUJ࡮৻⥸ญṶ ᐳ㐳㧔࠮࠶࡚ࠪࡦ㗅㧕૒⮮ రା㧔 ⽷ ࡅࡘ࡯ࡑࡦࠨࠗࠛࡦࠬᝄ⥝⽷࿅ࡅࡘ࡯ࡑࡦࠨࠗࠛࡦࠬ⎇ⓥ⾗Ḯࡃࡦࠢ㧕╴੗ ஜᯏ㧔ᣣᧄᱤ⑼ᄢቇ↢๮ᱤቇㇱ ⮎ℂቇ⻠ᐳ㧕㜞ᯅ ำሶ㧔ળᵤᄢቇ⍴ᦼᄢቇㇱ 㘩‛ᩕ㙃ቇ⑼㧕㑆ਛ ⎇৻㧔₡දක⑼ᄢቇ࡮࿖㓙ᢎ⢒⎇ⓥᣉ⸳ ⎇ⓥᡰេ࠮ࡦ࠲࡯㧕ጟ ஜ㧔ጟጊℂ⑼ᄢቇℂቇㇱ⥃ᐥ↢๮⑼ቇ⑼㧕ጊᧄ ⋥᮸㧔⮮↰଻ஜⴡ↢ᄢቇ౒ห೑↪⎇ⓥᣉ⸳ ಽሶ↢‛ቇ࡮⚵❱ൻቇ㧕ਛ᧛ ๺ᤘ㧔࿖┙ᚑ⢒ක≮⎇ⓥ࠮ࡦ࠲࡯⎇ⓥᚲ⮎೷ᴦ≮⎇ⓥㇱታ㛎⮎ℂ⎇ⓥቶ㧕ฎᳯᬮ↰⟤଻㧔ක⮎ၮ⋚⎇ⓥᚲ↢‛⾗Ḯ⎇ⓥㇱ⚦⢩⾗Ḯ⎇ⓥቶ㧕ᩙ↰ ⦟㧔ℂൻቇ⎇ⓥᚲ࡮ࡃࠗࠝ࡝࠰࡯ࠬ࠮ࡦ࠲࡯࡮⚦⢩᧚ᢱ㐿⊒ቶ㧕દୖ ብ৻㧔੩ㇺᄢቇ K25 ⚦⢩⎇ⓥᚲ ⷙ೙⑼ቇㇱ㐷㧕⮮੗ ਁ♿ሶ㧔ᗲ⍮⋵߇ࠎ࠮ࡦ࠲࡯ ਛᄩ∛㒮࡮⎇ⓥᚲ ಽሶ⣲≌ቇㇱ㧕ዊේ ᦭ᒄ㧔⁛┙ⴕ᡽ᴺੱ ක⮎ၮ⋚⎇ⓥᚲ 㔍∛࡮∔ᖚ⾗Ḯ⎇ⓥㇱ࡮ၭ㙃⾗Ḯ⎇ⓥቶ㧕ᣣᧄ⚵❱ၭ㙃ቇળ╙㧤㧡࿁ᄢળߩ㐿௅ߦ޽ߚࠅ‫ޔ‬਄⸥ߩవ↢ᣇߦߪ․ߦ߅ജᷝ߃ࠍ޿ߚߛ߈
߹ߒߚߎߣ‫ߦߎߎޔ‬ᗵ⻢↳ߒ਄ߍ߹ߔ‫ޕ‬  ᄢળ㐳 ᵻ㚅 ൟ㧔੩ㇺᄢቇ K25 ⚦⢩⎇ⓥᚲ ⷙ೙⑼ቇㇱ㐷㧕ᣣᧄ⚵❱ၭ㙃ቇળ╙㧤㧡࿁ᄢળߩ㐿௅ߦ޽ߚࠅ‫ޔ‬ਅ⸥ߩડᬺ㧔㧡㧜㖸㗅㧕ࠃࠅᄙᄢߥߏදജࠍ޿ߚ
ߛ߈߹ߒߚ‫ߦߎߎޕ‬ળຬ৻หࠍઍ⴫ߒߡᷓߊᗵ⻢↳ߒ਄ߍ߹ߔ‫ޕ‬




  





ᣣᧄ⚵❱ၭ㙃ቇળ╙㧤㧡࿁ᄢળᄢળ㐳 ᵻ㚅 ൟߏද⾥ડᬺ

K25 ࠕࠞ࠺ࡒࠕࠫࡖࡄࡦᩣᑼળ␠
ࠕ࠭ࡢࡦᩣᑼળ␠
ᩣᑼળ␠ࠕࡆ࡯
ᩣᑼળ␠කቇ↢‛ቇ⎇ⓥᚲ
ࠛࡓࠛࠬᯏེᩣᑼળ␠
ࠝ࡝ࡦࡄࠬᩣᑼળ␠
ᩣᑼળ␠ࠣ࡜ࠗ࠽࡯࡮ࠫࡖࡄࡦ
ࠦࠬࡕ࡮ࡃࠗࠝᩣᑼળ␠
ᩣᑼળ␠㜞⎇ࠦ࡯࠾ࡦࠣࠗࡦ࠲࡯࠽࡚ࠪ࠽࡞ᩣᑼળ␠
ᩣᑼળ␠⚦⢩⑼ቇ⎇ⓥᚲ
ࠨ࡯ࡕࡈࠖ࠶ࠪࡖࠨࠗࠛࡦ࠹ࠖࡈࠖ࠶ࠢᩣᑼળ␠
࠲ࠗ࠹࠶ࠢᩣᑼળ␠
ᄢ㓁ᣣ㉄ᩣᑼળ␠
࠲ࠞ࡜ࡃࠗࠝᩣᑼળ␠
&5 ࡈࠔ࡯ࡑࡃࠗࠝࡔ࠺ࠖࠞ࡞ᩣᑼળ␠
ᩣᑼળ␠࠻࡜ࡦࠬࡄ࡟ࡦ࠻
ᩣᑼળ␠࠻ࡒ࡯♖Ꮏᣣᧄࡌࠢ࠻ࡦ࡮࠺ࠖ࠶ࠠࡦ࠰ࡦᩣᑼળ␠
ᣣᧄࡌࠢ࠻ࡦ࡮࠺ࠖ࠶ࠠࡦ࠰ࡦᩣᑼળ␠
ᩣᑼળ␠࠾ࠦࡦࠗࡦࠬ࠹࠶ࠢ
ᣣᧄࠫࠚࡀ࠹ࠖࠢࠬᩣᑼળ␠
ᣣᧄࠛࠕ࡯࠹࠶ࠢᩣᑼળ␠
ᣣᧄࡃࠗ࡝࡯ࡦᩣᑼળ␠
ฎᴡ㔚᳇Ꮏᬺᩣᑼળ␠
ࡈ࠽ࠦࠪᩣᑼળ␠
ᩣᑼળ␠ࡌ࡝࠲ࠬ
ᩣᑼળ␠ࡑ࠷ࡏ࡯
ࡒ࡞࠹࠾࡯ࡃࠗࠝ࠹ࠢᩣᑼળ␠
ࡔ࡞ࠢᩣᑼળ␠
ࡗࡑ࠻⑼ቇᩣᑼળ␠
࡜ࠗࡈ࠹ࠢࡁࡠࠫ࡯࠭ࠫࡖࡄࡦᩣᑼળ␠
ᩣᑼળ␠࡝ࡊࡠ࠮࡞
๺శ⚐⮎ᩣᑼળ␠
ࡢ࠻࠰ࡦᩣᑼળ␠
๺⎇⮎ᩣᑼળ␠

ȗȭǰȩȠ 㻌 㻌ଐஜኵጢؔ᫱‫ ˟ܖ‬ᇹᲲ ‫˟ٻׅ‬







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ʮᣃ‫ ܖٻ‬ႊԗ࠰଺ᚘӨᚡࣞ᫾ ႊԗ࠰ᚡࣞțȸȫ Ტʮᣃࠊ߼ʮғӴဋஜထᲣ
‫˟ٻ‬ȆȸȞ  έᇢҔၲǛਃƏؔ᫱২ᘐ
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 ଐႸ    ࠰  உ  ଐ




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ங୴ଐ 

 

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㻌㻌㻌㻌

Ӗ˄



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᧏˟ਮਠ

 㻌㻌

 ˟ᧈ    ᤠங ߁ࢠ  ிʮ‫ܖٻܖٻ‬ᨈҔ‫ܖ‬ኒᄂᆮᅹ᧽‫ޓ‬၌धဃԡ߻‫ܖ‬ǻȳǿȸ ્‫ݧ‬ዴᄂᆮ᪸؏ 

㻌㻌㻌㻌





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‫ڜ‬ѕច‫ݣ‬ᝋ๫᫆ Ტӝ๫ƓǑƼȝǹǿȸᲣ



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ࡈᧈ    ˱ᕲΨ̮  ᝠ‫ׇ‬ඥʴȒȥȸȞȳǵǤǨȳǹਰᐻᝠ‫ ׇ‬ȒȥȸȞȳǵǤǨȳǹᄂᆮ᝻เȐȳǯ  




YIA-1

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51:Ŵ*':Ŵ*0(ᢡˡ‫ݰ܇‬λƴǑǔȒȈ‫ٶ‬Ꮱࣱ࠴ኬᏘƔǒ঺༌ᏁኬᏘƷјྙ 㻌ᑣƍЎ҄ᛔ‫ ݰ‬‫ܖٻܖٻ᧵ٻ‬ᨈ ᕤ‫ܖ‬ᄂᆮᅹ Ў‫܇‬ဃཋ‫ܖ‬Ў᣼ ཯ᇌᘍ૎ඥʴ ҔᕤؕႴᄂᆮ৑ ࠴ኬᏘСࣂȗȭǸǧǯȈ ཯ᇌᘍ૎ඥʴ ҔᕤؕႴᄂᆮ৑ ᩊ၏ȷ၌ध᝻เᄂᆮᢿ ؔ᫱᝻เᄂᆮܴ ʮᣃ‫ܖٻ‬ϐဃҔᅹ‫ܖ‬ᄂᆮ৑ ࠴ኬᏘҔ‫ܖ‬ᄂᆮǻȳǿȸ ኬᏘȗȭǻǷȳǰᄂᆮ᪸؏

‫ܖٻܖٻ᧵ٻ‬ᨈ ᳇Ჿ᳃ǻȳǿȸ   Ũ᭗‫ޛ‬ԧᨺ  ᆖ஭ Ϊ  ߷ᇢͤʚ  ࢟‫ޛ‬ԧӪ  ആʟ૨૙  Ӟ൶౿ဋ፦̬  ൦ӝᘽʂ 


YIA-2

ȒȈ‫ٶ‬Ꮱࣱ࠴ኬᏘƔǒᏴᐥኒᜧƴЎ҄Ƣǔɶ᧓ɶᏕᓶኬᏘƷ᭗јྙƳЎ҄ᛔ‫ݰ‬ඥƷ 㻌ᄩᇌ  ʮᣃ‫ ܖٻ‬K25 ኬᏘᄂᆮ৑   ŨЭ ˦ɟ ᧈᑔͤʚ




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ɟᑍ๫᫆ í  žᕤཋǢȃǻǤኒſࡈᧈ    ለʟ ͤೞ   ଐஜഫᅹ‫ܖٻ‬ဃԡഫ‫ܖ‬ᢿ ᕤྸ‫ ࡈᜒܖ‬㻌 ࡈᧈ    ᭗೛ ӽ‫˟   ܇‬඾‫ܖٻ‬ჺ஖‫ܖٻ‬ᢿ ᫢ཋ௿᫱‫ܖ‬ᅹ 

OG-1-1ǳȩȸǲȳȓȈȪǲȫᐏȁȣȳȐȸϋƴȒȈᘉሥϋႝኬᏘǛؔ᫱ƢǔƜƱưϐನሰƠƨᘉሥϋႝȢȇȫƷȐȪǢೞᏡ  ཯ᇌᘍ૎ඥʴ ᠾಅဃཋ᝻เᄂᆮ৑ ್ා‫׎‬ᇌ‫ܖٻܖٻ‬ᨈ߻‫   ࡅܖ‬Ũ‫ޢ‬ஜ ग़  ສɶᅙࢀ  บ᢫ଡ̢  ᇦຓ̢ଢ 

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

OG-1-2ɧര҄ᚌᐏɥႝኬᏘᲢK*%'0;ᲣǛဇƍƨაХນࣱᚾ᬴ˊஆඥƴ᧙Ƣǔᄂᆮ  ᕲဋ̬ͤᘓဃ‫ ܖٻ‬σӷМဇᄂᆮ଀ᚨ Ў‫܇‬ဃཋ‫ܖ‬ȷኵጢ҄‫ ܖ‬ᕲဋ̬ͤᘓဃ‫ ܖٻ‬Ҕ‫ܖ‬ᢿ აᅹ‫ܖ‬૙ܴ ଐஜȡȊȸȉ҄ታԼఇࡸ˟ᅈ ዮӳᄂᆮ৑ ‫ܤ‬μࣱᚸ̖ᄂᆮǰȫȸȗ țȸȦȸఇࡸ˟ᅈ ዮӳᄂᆮ৑ ؕႴ২ᘐᄂᆮܴ ‫׎‬ᇌҔᕤԼ᫢Լᘓဃᄂᆮ৑ ᕤྸᢿ ૼᙹᚾ᬴ඥᚸ̖ܴ    㻌Ũ‫ޛ‬ஜႺ೔  ࠯᣼᎓඙  ‫ޛ‬ɦ‫ܨ‬፦  ьᕲ፯Ⴚ  ˱ᕲ ค  ɶ஭૎࣓  Ҿ ԧ‫ ܨ‬᜿߷ሶ‫ؗ  ܨ‬ӝദʂ  ᜿ӝܑշ  ‫ ޽ݱ‬Ꮈ 

OG-1-3+PXKVTQ ႆဃ൒ࣱᚾ᬴ǁƷኬᏘЎ҄Ʒ‫ݰ܇׆ࣄׅ‬λƷᚾǈ   㻌‫᧵ٻ‬ഫᅹ‫ܖٻ‬ഫᅹྸ߻‫   ࡈᜒܖ‬Ũʻʟࢀɟ നဋଯʚ


OG-1-4ᕤཋᏁˊᜓငཋƷᚸ̖ƕӧᏡƳ 'ODT[QPKE5VGO%GNN6GUV '56 ඥ Ʒ౨᚛   㻌‫׎‬ᇌ঺ᏋҔၲᄂᆮǻȳǿȸ ᄂᆮ৑ ᕤд඙ၲᄂᆮᢿ   Ũɶ஭ԧଯ ဋɥଯʴ
 㻌ɟᑍ๫᫆ î  žϋᏕᓶኒኬᏘſࡈᧈ    ᧓ɶ ᄂɟ  ྏңҔᅹ‫ ܖٻ‬ᄂᆮૅੲǻȳǿȸ 㻌 ࡈᧈ    ༾‫ྸޛޢ  ͤ ޢ‬ᅹ‫ܖྸ ܖٻ‬ᢿ ᐮ࠿ဃԡᅹ‫ܖ‬ᅹ 

OG-2-1
0QVEJOGFKCVGFGRKIGPGVKETGIWNCVKQPKUETKVKECNHQTOCKPVGPCPEGQH

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RCPETGCVKEGPFQETKPGRTQIGPKVQTUXKCRQUUKDNGKPVGITCVKQPYKVJ*$')(CPF
%4(HCOKN[  ‫ྚؖ‬Ҕᅹ‫ ܖٻ‬Ҕ‫ܖ‬ᢿ Ў‫܇‬ဃཋ‫ ܖ‬ǽȸǯᄂᆮ৑ ቟‫   ׎‬Ũ௅ஜࢯʶ *WKUKPI/CTMXCPFGT/GWNGP6CNKVJC ࠯߃ദܑ  ᅳ ඲٫ 
8CNG9[NKG

OG-2-2ᲭഏΨኵጢϐನሰƷƨǊƷ‫׹ݱ‬ȩǸǢȫȕȭȸ‫׹‬ȐǤǪȪǢǯǿȸǷǹȆȠƷ᧏ႆிʮ५औ˟Ҕᅹ‫ ܖٻ‬ෞ֥҄Ꮑᐥϋᅹ ிʮ५औ˟Ҕᅹ‫ ܖٻ‬ᐮ࠿౨௹Ҕ‫ࡈᜒܖ‬ிʮ५औ˟Ҕᅹ‫ ܖٻ‬ဃ҄‫ ࡈᜒܖ‬ଢ඙‫ܖ߻ྸܖٻ‬ᢿ ‫׎‬ᇌज़௨ၐᄂᆮ৑ ǦǤȫǹ  ᢿ    㻌Ũ௅ஜշࢀ  ௅ිჷԧ  Э೛ƸǔƔ  ဋɶ ជ  ൨‫ڸ‬գʼ  ᣼ஜᅵ஬  ‫ ߷ٻ‬ฌ  Ⴛຓ ‫  ܣ‬Ⴛ߃ᒍ೔ 

OG-2-3ϵኽ̬‫܍‬ᏁኵጢƔǒƷᏁኬᏘЎᩉ  ‫׎‬ᇌ঺ᏋҔၲᄂᆮǻȳǿȸ ᐮ࠿ᄂᆮǻȳǿȸ έᇢҔၲ᧏ႆܴ   Ũᱣᕲ ʰ ዋ᣼එ ˦ 㻌

OG-2-4ǫȁǪȳࣱ‫ٶ‬ኄᄬࣱቩ‫܇‬ᙐӳ˳ƷᏁኬᏘƴ‫ݣ‬Ƣǔࢨ᪪  ӸӞ‫ܖٻܖٻދ‬ᨈ Ҕ‫ܖ‬ᄂᆮᅹ Ӹኄငಅఇࡸ˟ᅈ ӸӞ‫ދ‬ᄂᆮ৑ ‫ ܖٻޛޢ‬Ҕഫᕤ‫ܖ‬ዮӳᄂᆮᅹ  㻌*#$ ᄂᆮೞನȷ᧽‫ޓ‬ᄂᆮ৑ ఇࡸ˟ᅈȈȩȳǹȑȬȳȈ ӸӞ‫ܖٻ ܖٻދ‬ᨈ߻‫ܖ‬ᄂᆮᅹ ӸӞ‫ދ‬σᇌ၏ᨈ ȪǦȞȁȷʴ߻᧙ራǻȳǿȸ   Ũܷஜ፯ܑ  ᏿᭗ဌ፦औ  ᱣᕲࢀଢ  ᣼ӝබ૨  ‫ٻ‬ჽ࠳ɟ  ஭ແѨ̢  ᤠங Ꭷ  ൷᜿ന࣓  ื߷ Ҧ  ь‫ע‬ርҊ  ‫ޥ‬ဋ ʁ  ᬔ‫  ̮֒ئ‬௎ ᘌ඙  㻌ɟᑍ๫᫆ ï  žϐဃҔ߻‫ܖ‬ſࡈᧈ    ‫ޛ‬ஜ Ⴚ೔   ᕲဋ̬ͤᘓဃ‫ ܖٻ‬σӷМဇᄂᆮ଀ᚨ Ў‫܇‬ဃཋ‫ܖ‬ȷኵጢ҄‫ ܖ‬㻌 ࡈᧈ    ɶ஭ ԧଯ  ‫׎‬ᇌ঺ᏋҔၲᄂᆮǻȳǿȸ ᄂᆮ৑ᕤд඙ၲᄂᆮᢿ ᬴ܱᕤྸᄂᆮܴ 

OG-3-1ኬᏘǷȸȈᆢ‫ޖ‬ƴǑǔɤഏΨ࣎ሂኵጢನሰᢅᆉƴƓƚǔˊᜓᚸ̖  ଔᆖဋ‫ ܖٻ‬ȊȎྸ߻‫ܖ‬ᄂᆮೞನ ଔᆖဋ‫ ܖٻ‬ዮӳೞ఺߻‫ܖ‬ᅹ ிʮ‫܇ڡ‬Ҕᅹ‫ ܖٻ‬έᇢဃԡҔᅹ‫ܖ‬ᄂᆮ৑ ଔᆖဋ‫ ܖٻ‬ဃԡҔᅹ‫ܖ‬ᅹ   

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Ũь߷Ӑࠁ  ဋɶᘽʍ  ‫ק‬ӝѨʁ  ᧙ఌᅵɟ  ฌ൦ᢋʍ  ࠝဋ Ꭷ  ‫ޢ‬᣼ή‫ پ‬

OG-3-2ϐဃҔၲƴဇƍǔኬᏘǷȸȈƷǨȍȫǮȸˊᜓ  ଔᆖဋ‫ ܖٻ‬έᡶྸ߻‫ܖ‬ᄂᆮᅹ ဃԡҔᅹ‫ݦܖ‬ૌ ଔᆖဋ‫ ܖٻ‬ȊȎྸ߻‫ܖ‬ᄂᆮೞನ ிʮ‫܇ڡ‬Ҕᅹ‫ ܖٻ‬έᇢဃԡҔᅹ‫ܖ‬ᄂᆮ৑    㻌ŨЭ‫ ޛ‬ዋ᣺‫  ډ‬ь߷Ӑࠁ  ᧙ఌԧࠎ  ฌ൦ᢋʍ  ࠝဋ Ꭷ  ‫ޢ‬᣼ή‫ پ‬

OG-3-3ᚌᐏɥႝϐဃҔၲƴဇƍǔቬᐏɥႝǷȸȈƷૼᙹ᣻‫҄ޖ‬ඥƷ౨᚛  ிʮ‫ ܖٻ‬Ҕ‫ܖ‬ᢿ᧽‫ޓ‬၏ᨈ აᅹ‫ܖ‬૙ܴ ிʮ‫ ܖٻ‬Ҕ‫ܖ‬ᢿ᧽‫ޓ‬၏ᨈ ᚌᐏᆆౡᢿ    㻌Ũ್‫ރ‬ᛗɟ  ‫ޛ‬ɥ Ꭷ 

OG-3-4ᐯܼؔ᫱ᘙႝǸǧǤǹƴ‫ݣ‬Ƣǔ৴ဃཋឋƷࢨ᪪   㻌ఇࡸ˟ᅈǸȣȑȳȷȆǣȃǷȥȷǨȳǸȋǢȪȳǰ   Ũ᭗ᓬǈƖ ʟܼႩԧ ဋɶ஋ˊ ฌ൦፯Ҧ ‫ݱ‬ාҘᘽ ဣ ជɟᢹ




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π᧏ ؔ᫱ਦ‫ݰ‬ٟ᫱঺ᜒ፼˟Ტᇹ  ‫ׅ‬Უ

 



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㻌㻌˖ဒ    ଐஜኵጢؔ᫱‫ ˟ܖ‬૙ᏋᄂᆮǷǹȆȠ‫ۀ‬Ճ˟

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ࡈᧈ    Ӟ൶౿ဋ ፦̬  ཯ᇌᘍ૎ඥʴҔᕤؕႴᄂᆮ৑ 
WTᲢᲫᲣؔ᫱ؕႴ২ᘐǳȸǹಒᙲƴƭƍƯƷᛟଢ㻌 㻌         Ӟ൶౿ဋ፦̬ ૙ᏋᄂᆮǷǹȆȠ‫ۀ‬Ճ˟‫ۀ‬Ճᧈ 㻌

㻌ᲢᲬᲣؔ᫱ؕႴ২ᘐǳȸǹ +++ ƱኬᏘؔ᫱ٟᛐ‫ܭ‬ƴƭƍƯƷಒᙲᛟଢ

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         ᤠங߁ࢠ ଐஜኵጢؔ᫱‫ᧈ˟˟ܖ‬ 㻌ᲢᲭᲣؔ᫱ؕႴ২ᘐǳȸǹ ++ දॖໜ ൭ǊǒǕǔ২ᘐ 㻌         ɥဋࣙ̀ ૙ᏋᄂᆮǷǹȆȠ‫ۀ‬Ճ˟‫ۀ‬Ճ 㻌ᲢᲮᲣؔ᫱ؕႴ২ᘐǳȸǹ + දॖໜ ൭ǊǒǕǔ২ᘐ 㻌         ᧓ɶᄂɟ ؔ᫱ؕႴ২ᘐǳȸǹ + ʙѦ‫ޅ‬ 㻌ᲢᲯᲣؔ᫱ؕႴ২ᘐǳȸǹ +++ ؔ᫱ਦ‫ݰ‬ٟᚰ ੉ɨƱ᝻఍ᎍƷπᘙ 㻌         ᤠங߁ࢠ ଐஜኵጢؔ᫱‫ ᧈ˟˟ܖ‬ 㻌         Ӟ൶౿ဋ፦̬  ૙ᏋᄂᆮǷǹȆȠ‫ۀ‬Ճ˟‫ۀ‬Ճᧈ 

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






ǷȳȝǸǦȠᲫ žܱྵ҄ႸЭƷ࠴ኬᏘ඙ၲƱؔ᫱২ᘐſࡈᧈ    ɶ஭ ࠳‫ܖ҄ྸ  پ‬ᄂᆮ৑ ȐǤǪȪǽȸǹǻȳǿȸኬᏘ஬૰᧏ႆܴ 㻌 ࡈᧈ    ෌ᬐ ѱ  ʮᣃ‫ ܖٻ‬K25 ኬᏘᄂᆮ৑ᙹСᅹ‫ܖ‬ᢿᧉ 

S-1-1

ǼȎȕȪȸȒȈ '5K25 ኬᏘƷؔ᫱ǷǹȆȠƷᄩᇌ  



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‫׎‬ᇌ঺ᏋҔၲᄂᆮǻȳǿȸ ᄂᆮ৑ ϐဃҔၲǻȳǿȸ   Ũ᧺ʁ඾ ᒍঙ

S-1-2

K25 ኬᏘƷ‫ܤ‬μࣱƴ‫ݣ‬Ƣǔӕኵǈ  ʮᣃ‫ ܖٻ‬K25 ኬᏘᄂᆮ৑    㻌Ũ᭗೛ԧМ


S-1-3

ᐯܼኬᏘǛဇƍƨϐဃҔၲᙌԼƷԼឋሥྸ   㻌ఇࡸ˟ᅈǸȣȑȳȷȆǣȃǷȥȷǨȳǸȋǢȪȳǰ   Ũဣ ជɟᢹ


S-1-4

ɧര҄ហᘉྶЭᬝኬᏘఇƔǒƷហᘉྶƷʴ߻ဃင   㻌ྸ҄‫ܖ‬ᄂᆮ৑ ȐǤǪȪǽȸǹǻȳǿȸ ኬᏘ஬૰᧏ႆܴ   Ũంဋᑣ ɶ஭࠳‫پ‬

S-1-5

K25 ኬᏘƷዡᐏ၌धǁƷࣖဇ   㻌ྸ҄‫ܖ‬ᄂᆮ৑ ႆဃȷϐဃᅹ‫ܖ‬ዮӳᄂᆮǻȳǿȸ   Ũ᭗೛૎ˊ 㻌টᚃ˟Ტႊԗ࠰଺ᚘӨᚡࣞ᫾  ᨞ ‫׎‬ᨥʩ්țȸȫᲣ

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 ଐႸ    ࠰  உ  ଐ

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᣿୴ଐ 

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ɟᑍ๫᫆ ð  ž‫ٶ‬Ꮱࣱ࠴ኬᏘſ



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㻌 ࡈᧈ    ˙̽ ‫ܨ‬ɟ   ʮᣃ‫ ܖٻ‬K25 ኬᏘᄂᆮ৑ ᙹСᅹ‫ܖ‬ᢿᧉ 



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

ࡈᧈ    ంဋ ᑣ   ྸ҄‫ܖ‬ᄂᆮ৑ȷȐǤǪȪǽȸǹǻȳǿȸȷኬᏘ஬૰᧏ႆܴ OG-4-1ȒȈᏕࣱ࠴ኬᏘƷɥႝ᧓ᓶᆆᘍƴ᧙ɨƢǔ᠃ϙ‫)' ܇׆‬4 Ʒӷ‫  ܭ‬཯ᇌᘍ૎ඥʴҔᕤؕႴᄂᆮ৑ ᩊ၏၌ध᝻เᄂᆮᢿ ؔ᫱᝻เᄂᆮܴ ࠼޽‫ܖٻܖٻ‬ᨈ Ҕഫᕤ‫ܖ‬ዮӳᄂᆮᅹ ӝᏸͤࡍᅹ‫ݦܖ‬ૌ ӝᏸဃཋ߻‫ܖ‬Ў᣼   ŨஙఌҾҊࠎ  ඕ஭ Ң  ʚ߷ී೔  Ӟ൶౿ဋ፦̬ OG-4-25YKUU6 ኬᏘƱƷᆢ‫  ޖ‬ഏΨσؔ᫱ɦƴƓƚǔȒȈ '5K25 ኬᏘဌஹᏁኬᏘƷᏁ 㻌ኬᏘ঺༌҄ȷ̟ᡶೞನƷᚐௌ  ‫ ܖٻ᧵ٻ‬ᕤ‫ܖ‬ᄂᆮᅹ Ў‫܇‬ဃཋ‫ܖ‬Ў᣼ ҔᕤؕႴᄂᆮ৑ ࠴ኬᏘСࣂȗȭǸǧǯȈ ‫ ܖٻ᧵ٻ‬ᕤ‫ܖ‬ᄂᆮᅹ ҔᕤؕႴᅹ‫ܖ‬Ў᣼ ிʮ‫܇ڡ‬ҔҔ‫ ٻ‬έᇢဃԡҔᅹ‫ܖ‬ᄂᆮ৑ ҔᕤؕႴᄂᆮ৑ ᩊ၏၌ध᝻เᄂᆮᢿ ؔ᫱᝻เᄂᆮܴ ʮᣃ‫ܖٻ‬ϐဃҔᅹ‫ܖ‬ᄂᆮ৑ ࠴ኬᏘҔ‫ܖ‬ᄂᆮǻȳǿȸ ኬᏘȗȭǻǷȳǰᄂᆮ᪸؏‫ ܖٻ᧵ٻ‬/'+ ǻȳǿȸ   Ũᧈؕࡍʴ  ဋˊΰʁ  ᭗‫ޛ‬ԧᨺ  ‫ٻ‬೛ɟ‫  پ‬ആʟ૨૙  ᇌᑶᨻӪ  Ӟ൶౿ဋ፦̬  ߷ᇢͤʚ  ൦ӝᘽʂ 


OG-4-3ഏɭˊ‫׹‬ኬᏘᚸ̖ǷǹȆȠƷ᧏ႆ   㻌ҔᕤؕႴᄂᆮ৑ ᩊ၏ȷ၌ध᝻เᄂᆮᢿ ؔ᫱᝻เᄂᆮܴ   Ũᓌ ɤ̀ ᑅ‫ٻޛ‬᠗ ᕲஙࢢь ஙఌҾҊࠎ ௶Ҿ̀‫ ډ‬Ӟ൶౿ဋ፦̬


OG-4-4ီƳǔǰȫǳȸǹຜࡇƷؕᄽؔ‫ע‬ưЎᩉؔ᫱ƠƨȒȈႝᐎዴዜᑻኬᏘưƷ K25 ኬᏘ 㻌Ʒᛔ‫  ݰ‬ʮᣃ‫ ܖٻ‬K25 ኬᏘᄂᆮ৑ ᙹСᅹ‫ܖ‬ᢿᧉ   Ũ˙̽‫ܨ‬ɟ ൨೛૨‫ؗ ܇‬Џ୓‫ ܇‬෌ᬐ ѱ

OG-4-5࠴ኬᏘؔ᫱২ᘐƴƓƚǔǯȩǲဌஹǳȩȸǲȳƷஊјࣱ  ҔᕤؕႴᄂᆮ৑ᩊ၏ȷ၌ध᝻เᄂᆮᢿ ؔ᫱᝻เᄂᆮܴ ᅦʟ‫ܖٻܖٻ‬ᨈ߻‫ܖ‬ᄂᆮᅹ ଐᓙ҄‫ܖ‬ఇࡸ˟ᅈ ᒉ཰ฺǨȍȫǮȸᄂᆮǻȳǿÜ    㻌Ũ௶Ҿ̀‫  ډ‬ɤ஭ኝˊ  ᅦஜ ͤ  ‫ޛ‬ஜ፽‫  ٽ‬ᡐ џ೔  ɥဋᬐ‫  ډ‬ဪৎҦӐ လɦଡር  ᭗؉գɟ  ‫ݢ‬ဋᎧ  Ӟ൶౿ဋ፦̬ 

OG-4-6ȒȈ‫ٶ‬Ꮱࣱ࠴ኬᏘƷዼॸϵኽඥƴǑǔኬᏘϵኽȷᚐϵƴƓƚǔોծƷ౨᚛  ཯ ҔᕤؕႴᄂᆮ৑ ᩊ၏ȷ၌ध᝻เᄂᆮᢿ ؔ᫱᝻เᄂᆮܴ ,%4$ ኬᏘȐȳǯ ʮᣃ‫ܖٻ‬ϐဃҔᅹ‫ܖ‬ᄂᆮ৑ ࠴ኬᏘҔ‫ܖ‬ᄂᆮǻȳǿȸ ኬᏘȗȭǻǷȳǰᄂᆮ᪸؏ Ũ௎ဋǈƲǓ  ‫ݱ‬ຓ ᘽ  ܼ஭‫ݩ‬ٟ  ௶Ҿ̀‫ݱ  ډ‬Ҿஊࢀ  Ӟ൶౿ဋ፦̬  㻌

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OE-1

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OE-2

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OE-4

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OE-5

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K25 ኬᏘᄂᆮƷᡶ‫  ޒ‬‫ޛ‬ɶ ˦ࢄ έဃ  ʮᣃ‫ ܖٻ‬K25 ኬᏘᄂᆮ৑    

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S-2-1

࢟७СࣂƕɨƑǔೞᏡ᩿Ʒ‫ ҄٭‬ᏁኬᏘИˊؔ᫱Ʒኺ᬴Ɣǒ  



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S-2-2

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S-2-3

ኬᏘ‫ٳ‬ȞȈȪȃǯǹƷ‫ٶ‬ಮࣱƱȆȸȩȸȡǤȉؔ᫱ؕ஬   㻌‫ ܖٻ᧵ٻ‬ᖨႉឋᄂᆮ৑
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S-2-4‫ٶ‬Ꮱࣱ࠴ኬᏘƷЎ҄ǛǵȝȸȈƢǔኬᏘ‫ٳ‬࿢‫  ؾ‬ 㻌༇ஜ‫ ܖٻ‬ႆဃҔ‫ܖ‬ᄂᆮ৑   Ũባ ଯᑽ
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‫    ᧈ˟ٻ‬෌ᬐ ѱ  ʮᣃ‫ ܖٻ‬K25 ኬᏘᄂᆮ৑ᙹСᅹ‫ܖ‬ᢿᧉ 㻌

PROGRAMSL

Induction of Pluripotency by Defined Factors:
SHINYA YAMANAKA,
Center for iPS Cell Research and Application (CiRA), Kyoto University

S-1-1

A Novel Xeno-Free Defined Condition for Culture of Human Embryonic Stem Cells and Human induced
Pluripotent Stem Cells:
HIDENORI AKUTSU,
Center for Regenerative Medicine, National Research Institute for Child Health and Development, Tokyo,
Japan

S-1-2

The project for the evaluation of human iPS cells:
KAZUTOSHI TAKAHASHI,
Center for iPS cell research and application

S-1-3

Quality control of autologous cell product for regenerative medicine.:
KENICHIRO HATA,
Japan Tissue Engineering Co., Ltd.

S-1-4

In vitro production of red blood cells from immortalized human erythroid progenitor cell lines:
RYO KURITA, YUKIO NAKAMURA,
Cell Engineering Division, BioResource Center, RIKEN, Tsukuba, Japan

S-1-5

Application of iPS cells to retinal diseases:
MASAYO TAKAHASHI,
Center for Developmental Biology, RIKEN

S-2-1

Functional changes induced by morphological regulation in primary hepatocyte culture:
SHIN ENOSAWA,
National Center for Child Health and Development

S-2-2

Small Molecule Tools for Cell Therapy:
MOTONARI UESUGI,
Institute for Integrated Cell-Material Sciences & Institute for Chemical Research, Kyoto University, Uji,
Japan

S-2-3

Toward engineering of designer substrates with defined extracellular matrix proteins:
KIYOTOSHI SEKIGUCHI,
Institute for Protein Research, Osaka University, Suita, Japan

S-2-4

The role of extracellular matrices in guiding ES/iPS cell differentiation into hepatic cells:
SHOEN KUME,
Institute of Molecular Embryology and Genetics, Kumamoto University

YIA-1

Efficient generation of functional hepatocytes from human pluripotent stem cells by SOX17, HEX andHNF4alpha transduction:
KAZUO TAKAYAMA1,2, MITSURU INAMURA1,2, KENJI KAWABATA2, KAZUFUMI KATAYAMA1,FUMINORI SAKURAI1, MIHO FURUE-KUSUDA3,4, HIROYUKI MIZUGUCHI1,2,5,
1

Laboratory of Biochemistry and Molecular Biology, Graduate School of Pharmaceutical Sciences, Osaka

University㻌 2Laboratory of Stem Cell Regulation, National Institute of Biomedical Innovation㻌 3Laboratoryof Cell Cultures, Department of Disease Bioresources Research, National Institute of Biomedical Innovation㻌
4

Laboratory of Cell Processing, Institute for Frontier Medical Sciences, Kyoto University㻌 5The Center for

Advanced Medical Engineering and Informatics, Osaka University
YIA-2

Monitoring and robust induction of intermediate mesoderm from human iPSCs/ESCs:
SHIN-ICHI MAE, KENJI OSAFUNE,
Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan

WT

Lecture of Cell Culture techniques-To develop a master of cell culture- organized by the JTCA education& research committee:
KENICHI MANAKA3, TADAYOSHI UEDA2, MAKIKO FUJII5, ISAO ASAKA6, MIHO FURUE K1,
TAKAHIKO SUZUKI4,
1

Laboratory of Cell Cultures, Department of Disease Bioresources Research, National Institute of

Biomedical Innovation㻌 2Dainippon Sumitomo Pharma Co.,Ltd.㻌 3Tissue Culture Research Center, Dokkyo
University School of Medicine㻌 4Research Resources and Support -Radiation Biology, Center for Disease
Biology and Integrative Medicine, Graduate School of Medicine and Faculty of Medicine, The University ofTokyo㻌 5Division of Molecular Oncology, Aichi Cancer Center Research Institute㻌 6Department ofRegulatory Science Center for iPS Cell Rsearch and Application, Kyoto University

OE-1

Mortalin based imaging reagents: outcome of the cell culture studies:
SUNIL KAUL, TOMOKO YAGUCHI, RENU WADHWA,
National Institute of Advanced Industrial Science & Technology (AIST), Central 4, 1-1-1 Higashi, Tsukuba
305-8562, Japan

OE-2

Dose-dependent regulation of cell proliferation phenotypes by a p53-regulatory protein, CARF:
RUMANI SINGH, CAROLINE CHEUNG, SUNIL KAUL, RENU WADHWA,
National Institute of Advanced Industrial Science & Technology (AIST), Central 4, 1-1-1 Higashi, Tsukuba
305-8562, Japan

OE-3

Anticancer activity in the alcoholic and water extracts of Ashwagandha leaves: Identification and molecularcharacterization by cell culture models:
RENU WADHWA, NAVJOT SHAH, DIDIK PRIYANDOKO, SUNIL KAUL,
National Institute of Advanced Industrial Science & Technology (AIST), Central 4, 1-1-1 Higashi, Tsukuba
305-8562, JapanOE-4

hnRNPK, a target for cancer cell metastasis: evidence from the cell-based screening of intracellular antibody
library:
RAN GAO, SUNIL KAUL, RENU WADHWA,
National Institute of Advanced Industrial Science & Technology (AIST), Central 4, 1-1-1 Higashi, Tsukuba
305-8562, Japan

OE-5

Development of RAGE-inhibitor delivered into cells:
ENDY WIDYA PUTRANTO1, HITOSHI MURATA1, KEN-ICHI YAMAMOTO1, KEN KATAOKA1,
JUN-ICHIRO FUTAMI2, HIDENORI YAMADA2, MASAKIYO SAKAGUCHI1, NAM-HO HUH1,
1

Department of Cell Biology, Okayama University Graduate School of Medicine, Dentistry, andPharmaceutical Sciences, Okayama, Japan㻌 2Department of Bioscience and Biotechnology, Okayama
University Graduate School of Natural Science and Technology, Okayama, Japan
OG-1-1Barrier function of vascular endothelial models reconstructed in a collagen vitrigel membrane chamber byculturing human vascular endothelial cells:
CHIKA OKAMOTO1, YOSHIHIRO HAMANAKA1,2, MASATOSHI WATANABE2, TOSHIAKITAKEZAWA1,
1National Institute of Agrobiological Sciences㻌 2Graduate School of Engineering Yokohama National

University
OG-1-2

The research of Alternative method at eye irritation using the new immortalized human corneal epithelium
cell line.:
NAOKI YAMAMOTO1, KOJI HIRANO2, HIROMI YAMASHITA1, YOSHINAO KATOU3, ATSUSHISATOU3, MASASHI NAKAMURA4, KAZUHIRO HARA4, ATSUHIRO TANIKAWA2, MASAYUKI
HORIGUCHI2, KOKI TANIGUCHI1, HAJIME KOJIMA5,
1

Laboratory of Molecular Biology & Histochemistry, Fujita Health University Joint Research Laboratory,

Aichi, Japan㻌 2Department of Ophthalmology, Fujita Health University School of Medicine, Aichi, Japan㻌
3

Research Laboratories, Nippon Menard Cosmetic Co., Ltd., Aichi, Japan㻌 4General Research &Development Institute, Hoyu Co., Ltd., Aichi, Japan㻌 5Japanese Center for the Validation of Alternative
Methods (JaCVAM), Division of Pharmacology, National Institute of Health Sciences, Tokyo, Japan
OG-1-3

An attempt to the cell recovery factor for in vitro㻌 embryotoxicity test :KOICHI IMAI, SHOJI TAKEDA,
Department of Biomaterials, Osaka Dental UniversityOG-1-4

Improvement of Embryonic Stem Cell Test with Hepatocyte co-culture:
KAZUAKI NAKAMURA, AKITO TANOUE,
Department of Pharmacology, National Research Institute for Child Health and Development, Tokyo, Japan

OG-2-1

Notch-mediated epigenetic regulation is critical for maintenance of pancreatic endocrine progenitors via
possible integration with HB-EGF and CRF-family:
MASAHITO MATSUMOTO1,2, MARK HUISING2, TALITHA VAN DER MEULEN2, MASATAKAHIRASAKI1, YASUHISA NOGI1, WYLIE VALE2,
1

Department of Molecular Biology, Saitama Medical University, Saitama, Japan㻌 2The Salk Institute for

Biological Studies, Peptide Biology Laboratories, La Jolla, USA
OG-2-2 Development of a compact radial flow bioreactor system for three dimensional tissue reconstruction:
YOSHIHIRO MATSUMOTO1,5, TOMOKAZU MATSUURA2, HARUKA MAEHASHI2, KEN
TANAKA1, KEISUKE NAGATSUMA1, HIDEKI NOMOTO3, KIYOSHI OHKAWA3, MAMORUAIZAWA4, HIDEKI AIZAKI5,
1

Division of Gastroenterology and Hepatology, Department of Internal Medicine, the Jikei University

School of Medicine㻌 2Department of Laboratory Medicine, the Jikei University School of Medicine㻌
3

Department of Biochemistry, the Jikei University School of Medicine㻌 4Laboratory of Biomaterials,

Department of Applied Chemistry, School of

Science and Technology, Meiji University 5Department of

Virology II, National Institute of Infectious Diseases
OG-2-3 Living hepatocyte isolation from cryopreserved liver tissue:
RYO SAITO, SHIN ENOSAWA,
National Center for Child Health and Development
OG-2-4 Influence of Polysaccharide Functionalized Magnetic Nanoparticles on Hepatocytes: YOSHITAKAMIYAMOTO1, YUMIE KOSHIDAKA1, HIROAKI SAITO2, HIROFUMI NOGUCHI3, KOICHI OISHI1,
KATSUTOSHI MURASE2, SATOSHI SUZUKI4, TAKESHI IKEYA5, HIROSHI YUKAWA1,NORITADA KAJI6, HISASHI IWATA7, YOSHINOBU BABA6, SHUJI HAYASHI1,
1

Nagoya University Graduate School of Medicine㻌 2MEITO Sangyo Co., Ltd., Nagoya Research Laboratory㻌

3

Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical㻌 4Research Laboratories,

HAB Research Organization㻌 5Transparent Inc.㻌 6Nagoya University Graduate School of Engineering,
Nagoya University㻌 7Nagoya Kyoritsu Hospital, Department of Orthopaedic Surgery
OG-3-1

Cell metabolism in three-dimensional cardiac tissues fabricated by layering cell sheets in vitro:
YUKI KAGAWA1, YUYA TANAKA2, KATSUHISA SAKAGUCHI2, HIDEKAZU SEKINE3, TATSUYASHIMIZU3, SATOSHI TSUNEDA4, TERUO OKANO3,
1

Institute for Nanoscience and Nanotechnology, Waseda University, Tokyo, Japan㻌 2Department of Modern

Mechanical Engineering, Waseda University, Tokyo, Japan㻌 3Institute of Advanced Biomedical Engineeringand Science, Tokyo Women's Medical University, Tokyo, Japan㻌 4Department of Life Science and Medical
Bioscience, Waseda University, Tokyo, JapanOG-3-2 Energy metabolism of cell sheets using in regenerative medicine:
ERINA MAEYAMA1, YUKI KAGAWA2, WAKI SEKINE3, TATSUYA SHIMIZU3, SATOSHITSUNEDA1, TERUO OKANO3,
1

Department of Life Science & Medical Bioscience, Graduate School of Advanced Science andEngineering, Waseda University, Tokyo, Japan㻌 2Institute for Nanoscience & Nanotechnology, Waseda
University, Tokyo, Japan㻌 3Institute of Advanced Biomedical Engineering & Science, Tokyo Women's
Medical University, Tokyo, Japan
OG-3-3 The new technique that can make multilayer mucous membrane epithelium sheet to use for corneal
epithelium regenerative medicine.:
SEIICHI YOKOO1, SATORU YAMAGAMI2,
1

Department of Opthalmology, The University of Tokyo Hospital㻌 2Corneal Transplantation Section, The

University of Tokyo Hospital
OG-3-4 Effects of antibiotics on autologous-cultured-epidermis product, JACE:
MIKI TAKAHAGI, MASUKAZU INOIE, TOMOYO TANAKA, YOSHIHIRO SHIMIZU, CHIHIROKOHOMA, KEN-ICHIRO HATA,
Japan Tissue Engineering Co., Ltd., Aichi, Japan
OG-4-1

Identification of EGR1 associated with EMT in human embryonic stem cells:
MASAKI KINEHARA1, SUGURU KAWAMURA2, HIROKI NIKAWA2, MIHO FURUE KUSUDA1,
1

Laboratory of Cell Cultures, Department of Disease Bioresources Research, National Institute of

Biomedical Innovation, Osaka.㻌 2Department of Oral Biology & Engineering, Division of Oral Health
Sciences, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima.
OG-4-2 The promotion of hepatic maturation of human pluripotent stem cells in 3D co-culture using Type I collagenand Swiss 3T3 cell sheets:
YASUHITO NAGAMOTO1,2, KATSUHISA TASHIRO2, KAZUO TAKAYAMA1,2, KAZUO OHASHI4,
FUMINORI SAKURAI1, MASASHI TACHIBANA1, MIHO K FURUE5,6, KENJI KAWABATA2,3,
HIROYUKI MIZUGUCHI1,2,7,
1

Laboratory of Biochemistry and Molecular Biology, Graduate School of Pharmaceutical Sciences, Osaka

University, Osaka, Japan㻌 2Laboratory of Stem Cell Regulation, National Institute of Biomedical
Innovation, Osaka, Japan㻌 3Laboratory of Biomedical Innovation, Graduate School of Pharmaceutical
Sciences, Osaka University, Osaka, Japan㻌 4Institute of Advanced Biomedical Engineering and Science,
Tokyo Women's Medical University, Tokyo, Japan㻌 5Laboratory of Cell Cultures Department of Disease
Bioresources National Institute of Biomedical Innovation, Osaka, Japan㻌 6 Laboratory of Cell Processing,
Institute for Frontier Medical Sciences, Kyoto University, Kyoto, Japan㻌 7The Center for Advanced Medical
Engineering and Informatics, Osaka University, Osaka, JapanOG-4-3 Development of Advanced Evaluation System for Pluripotent Stem Cells via Imagingcytometry:
MIKA SUGA, DAIKI TATEYAMA, AYAKA FUJIKI, MASAKI KINEHARA, KANA YANAGIHARA,MIHO FURUE-KUSUDA,
Laboratory of Cell Cultures, Department of Disease Bioresources Research, National Institute of Biomedical
Innovation
OG-4-4 iPS cell induction of fibroblasts isolated from human skin using different glucose concentration of basal
medium:
KOICHI IGURA, AYAKO NAGAHASHI, TOMOKO HORIKIRI, ISAO ASAKA,
Department of Regulatory Science, Center for iPS Cell Research and Application (CiRA), Kyoto University,Japan
OG-4-5 The effect of jellyfish-collagen on human stem cell culture: KANA YANAGIHARA1, SUMIYO
MIMURA1, KEN FUKUMOTO2, SHOTA YAMAMOTO2, YUUKI SAKO2, KANA UEDA3, HIROTOMOBANKO3, MASANORI HATASHITA4, KEIICHI TAKAGI4, SATOSHI TERADA2, MIHOFURUE-KUSUDA1,
1

Laboratory of Cell Cultures, Department of Disease Bioresources, National Institute of Biomedical

Innovation㻌 2Faculty of Engineering, University of Fukui㻌 3NICCA CHEMICAL CO., LTD㻌 4The Wakasa
Wan Energy Research Center
OG-4-6 Simple improvement of the cryopreservation method for the human ES and iPS cells:
MIDORI HAYASHIDA1, YUTAKA OZAWA1, MASASHI IEMURA1, KANA YANAGIHARA1,
ARIHIRO KOHARA1, MIHO FURUE-KUSUDA1,2,
1

JCRB Cell Bank, Laboratory of Cell Cultures, Research on Disease Bioresources, National Institute of

Biomedical Innovation㻌 2Laboratory of Cell Processing, Institute for Frontier Medical Sciences, Kyoto
University
OG-4-7

Simple cryopreservation of mouse and primate ES/iPS cells in a new freezing medium:
SHINSUKE IMAMATSU1, SUNGHO AHN2, KENZO BAMBA3, HIROSATO OKAZAKI1, YOU-ICHITAGAWA2,
1

LYMPHOTEC Inc.㻌 2Department of Biomolecular Engineering, Graduate School of Bioscience andBiotechnology, Tokyo Institute of Technology, Japan㻌 3Nippon Genetics Co.,Ltd