June 1, 2020
Sysmex Corporation
OPTiM Corporation

Sysmex and OPTiM Jointly Establish New Company to Plan, Develop andOperate Medical AI and IoT Open Platforms and Digital Transformation Solutions
Sysmex Corporation (HQ: Kobe, Japan; Chairman and CEO: Hisashi Ietsugu) and OPTiM
Corporation (HQ: Minato-ku, Tokyo, Japan; President: Shunji Sugaya) jointly established and began
conducting operations at D’PULA Medical Solutions Corporation on June 1, 2020. The company isin charge of planning, developing, and operating solution services that leverage open platforms andapplications related to digital medicine.
In recent years, innovative medical modalities and technological innovations such as artificial
intelligence (AI) and the Internet of Things (IoT) have driven the digital provision of medical
information in such areas as monitoring patient’s intaking drugs and future care based on individual
pathologies. At the same time, the provision of digital medicine for therapeutic applications has
gained marketing approval. The digital transformation through the analysis and utilization of thisdiverse medical data is closely linked with personalized medicine (the provision of healthcare
optimized for individual patients). This situation is opening up new medical possibilities for themanagement of overall information and appropriate support of individual processes from the time apatient is healthy throughout the process (the “patient journey”) of testing and diagnosis after
contracting a disease, treatment, preventing the disease from recurring or worsening, and eventuallyon to the terminal phase.
In February 2019, Sysmex and OPTiM reached an agreement on a comprehensive businessalliance* to accelerate the commercialization of digital medicine to support next-generation
healthcare and diagnostics, and the two companies have since been conducting joint initiatives. Inaddition, since November 2019 the two companies have engaged in considerations to reach a basic
agreement to establish a joint venture, leading to the establishment of D’PULA Medical Solutions.
The name of the joint venture derives from the concept of using these digital technologies andmedical data to provide solutions that act as a bridge linking individuals and medicine. The newcompany aims to use medical AI and IoT platforms to seamlessly connect medical information thathas been separated to date and to engage in the business of developing and operating scientifically
based digital medical solutions. At the core of this business are “medical AI and IoT platforms,” openplatforms that involve collaboration among diverse vendors and user companies and enable thedevelopment and inclusion of treatment applications. In addition, the new company will provide a
support service to assist in obtaining marketing approval for developed applications.
Currently, the new company is engaged in the development of medical AI and IoT platform prototypes.
Going forward, it will move forward with full-fledged discussions regarding collaboration withpharmaceutical companies and medical device manufacturers.

By maximizing the synergies between the two companies, Sysmex and OPTiM aim to continue
contributing to advances in healthcare and the healthy lives of people by developing andcommercializing solution services that utilize medical IT platforms employing advanced AI and IoTtechnology.

Overview of the New Company
Name:
D’PULA Medical Solutions Corporation
Location:
7-1-1 Onoedori, Chuo-ku, Kobe, Japan
Establishment: June 1, 2020
Capital:¥50 million (legal capital surplus: ¥50 million)
Ownership:
Sysmex 51%, OPTiM 49%
Executives:
Junya Inoue, President(Vice President, Clinical Innovation Division, Sysmex Corporation)
Hideki Yoshimura, Vice-President(Director, Healthcare Business Department, Business Headquarters,
OPTiM Corporation)
Business:Development, operation and maintenance of IT solutions, platforms andapplications related to digital medicine, as well as support services for
obtaining marketing approval

Reference
November 1, 2019 news release: “Sysmex and OPTiM Reach a Basic Agreement on theEstablishment of a Joint Venture to Accelerate the Commercialization of Digital Medicine toSupport Next-Generation Healthcare and Diagnostics: Aiming toward the Early-Stage Provisionof Platforms and Applications Related to Digital Medicine”
https://www.optim.com/news/20191101-pressrelease

Terminology* Comprehensive business alliance between Sysmex OPTiM:
In the area of advanced medicine, Sysmex and OPTiM have formed a business alliance andhave been collaborating on initiatives to combine Sysmex’s extensive expertise and global
sales and service network in the medical field with OPTiM’s “Cloud IoT OS” and other AI andIoT services and technologies. Through this alliance, we aim to use the information obtainedby connecting medical devices over networks, and analyzing the data using AI employing
open platforms for the early-stage development and global rollout of new medical IT solutions.