Poster Program

July 25th (Thu)
Oral Presentation 13:25-14:40 (Main Hall)
Discussion 14:40-15:50 (Annex Hall)
1P-01◆ Oral Presenter

Sodium Hypochlorite Pentahydrate: Effective Oxidant for Organic Reactions

Tomohide Okada*（Market Development Department, Chemicals Division, Nippon Light Metal
Company, Ltd.）
1P-02

Antidiabetic Materials Produced by Paenibacillus Fermentation

San-Lang Wang* 1, Van Bon Nguyen 2 （ 1 Department of Chemistry, Tamkang University, 2
Department of Science and Technology, Tay Nguyen University）
1P-03

Synthesis and Characterization of Epoxies Using Self-Assembled Nanofibrillar as Scaffolds

Wei-Chi Lai*, Ruey-Yi Hsia（ Department of Chemical and Materials Engineering, Tamkang
University）
1P-04

One-Pot Preparation of 3-Arylpyrazoles and 3-Arylisoxazolines from Arenes

Takahiro Yamamoto*, Hideo Togo（Graduate School of Science, Chiba University）
1P-05

Advantages of Metal Ligand Complexes/Pre-Catalysts in Catalytic Reactions Compared toin situ Systems
Yoshiaki Horiguchi*（Precious Metals Chemistry, Umicore Japan KK.）
1P-06

One-Pot Transformation of Primary Alcohols into 3-Aryl- and 3-Alkylisoxazoles and-pyrazoles.
Eiji Kobayashi*, Hideo Togo（Graduate School of Science, Chiba University）
1P-07

Structure and Reactivity of Aromatic Radical Cations Generated by FeCl3

Takahiro Horibe*, Shuhei Ohmura, Kazuaki Ishihara（Graduate School of Engineering, Nagoya
University）
1P-08

Establishment of the Continuous Synthesis of Ceramide (D-erythro-CER[NDS]) via

Oxo-Tethered Ruthenium Complex Catalyzed Asymmetric Transfer Hydrogenation using Pipe-Flow
ReactorMasahiro Kuwana* 1,2, Taichiro Touge 1, Yasuhiro Komatsuki 1, Shigeru Tanaka 1, Hideki Nara
1,KazuhikoMatsumura 1, Noboru Sayo 1, Yoshinobu Kashibuchi 2, Takao Saito 2（1 Corporate

Research & Development Division, Takasago International Corporation, 2 Process Development
Department, Takasago Chemical Corporation）

1P-09Highly Efficient Synthesis of Pyrrole-Imidazole Amide Sequence for Application to

DNA-Binding Polyamides
Takahiko Murata*, Shohei Yamamoto, Akira Nishiyama（Pharma & Supplemental Nutrition
Solutions Vehicle, KANEKA CORPORATION）
1P-10

Device Performance Improvement of Double-unit Air Gap Membrane Distillation Module

for Seawater Desalination
Chii-Dong Ho* 1, Luke Chen 2, Yu-An Chen 1, Chi-Hsiang Ni 1（1 Department of Chemical andMaterials Engineering, Tamkang University, 2 Water Resources and Environmental Engineering
Department, Tamkang University）
1P-11

anti-Selective Catalytic Asymmetric Nitoaldol Reaction of α-Keto Esters: Intriguing

Solvent Effect, Synthesis of APIs, and Flow Reaction
Tomoya Karasawa* 1, Raphaël Oriez 2, Naoya Kumagai 2, Masakatsu Shibasaki 2 （ 1 Process
Research & Development Laboratories, Sumitomo Dainippon Pharma Co., Ltd., 2 Institute ofMicrobial Chemistry (BIKAKEN)）
1P-12

◆

Development of New Catalytic Synthetic Methods of N-Unprotected Ketimines

Hiroyuki Morimoto*, Yuta Kondo, Kazuhiro Morisaki, Tetsuya Kadota, Yoshinobu Hirazawa,
Takashi Ohshima（Graduate School of Pharmaceutical Sciences, Kyushu University）
1P-13

Safe and Scalable Aerobic Oxidation by 2-azaadamantan-2-ol (AZADOL)/NOx Catalysis:

Large-Scale Preparation of Shi’s Catalyst
Yusuke Sasano 1, Hikaru Sato* 2, Shinsuke Tadokoro 2, Masami Kozawa 2, Yoshiharu Iwabuchi 1（1Department of Organic Chemistry, Graduate School of Pharmaceutical Sciences, Tohoku University,
2 Chemical Research Laboratory, Nissan Chemical Corporation）

1P-14

Research on the Adsorptive Condition of Copper (Ⅱ) Ion with the Use of Ephippia

Azusa Oyama*, Saya Oikawa*, Nanami Kannno*, Noa Haneishi*, Kazunari Takahashi（Iwate
Prefectural Mizusawa High School）
1P-15

Efficient Synthesis of a 5α-Reductase Inhibitor, 3-(Tetrazol-5-yl)-3,5-pregnadien-20-one

through Allylic Rearrangement of Cyanophosphates
Shinya Harusawa*, Hiroki Yoneyama, Yoshihide Usami（Osaka University of Pharmaceutical
Sciences）
1P-16◆

Catalytic Transfer Hydration of Cyanohydrins to alpha-Hydroxyamides

Tomoya Kanda, Asuka Naraoka, Hiroshi Naka*（Graduate School of Science and Research Center
for Materials Science, Nagoya University）

1P-17

Stereo-Defined Scaffold Strategy for Tamoxifens from (E)-1-Bromo-2-iodoalkenes.

Yoshino Fujii*, Yuka Tamura, Nako Hashimoto, Naoki Endo, Tetsuo Iwasawa（Department ofMaterials Chemistry, Ryukoku University）
1P-18

Crystallization Mechanisms Hiding Between Your Samples

Mayu Nakatsukasa*, Des O’Grady（AutoChem Team, BU LAB Instruments, Mettler Toledo K.K.）
1P-19

VARIOUS MANUFACTURING APPROACHES TO POORLY SOLUBLE PEPTIDES

Go Shiino*, Aiko Hasegawa, Takaharu Matsuura, Shunsuke Ochi, Yoshinori Murata（API R&DLaboratory, CMC R&D Division, Shionogi & Co., Ltd.）
1P-20

◆

Development of an Efficient Manufacturing Process for E2212 toward Rapid

Clinical Introduction
Minetaka Isomura*, Taiju Nakamura, Katsuya Tagami（API Research Japan, Pharmaceutical
Science & Technology CFU, Medicine Development Center, Eisai Co. Ltd.）
1P-21

Asymmetric route to a chiral heterocyclic amine toward efficient manufacturing process

Sayuri Hirano*, Masatoshi Yamada, Mitsuhisa Yamano（Chemical R&D Division, Spera Pharma,
Inc.）
1P-22

Aromatic Halogenation Using N-Halosuccinimide and PhSTMS or PhSSPh

Yuuka Hirose, Mirai Yamazaki, Misa Nogata, Akira Nakamura, Tomohiro Maegawa*（Laboratory ofMedicinal Chemistry, School of Pharmaceutical Sciences, Kindai University）
1P-23

Stereospecific Synthesis of 1,5-Disubstituted Tetrazoles from Ketoximes via Beckmann

Rearrangement Utilizing Diphenyl Phosphorazidate
Kotaro Ishihara*, Yuki Kobayashi, Takayuki Shioiri, Masato Matsugi（Faculty of Agriculture, Meijo
University）
1P-24

Post-treatment Free Synthesis of Fairy Chemicals Using Fine Bubble and Flow

Optimization Method
Keiya Matsuo*, Kohei Sato, Tetsuo Narumi, Nobuyuki Mase（Applied Chemistry and Biochemical
Engineering Course, Department of Engineering, Graduate School of Integrated Science andTechnology, Shizuoka University）
1P-25

Reaction Optimization Using Microwave-assisted Continuous Flow Reactor with In-line

Analysis
Takuya Kon*, Kohei Sato, Tetsuo Narumi, Kazuhiro Takeda, Nobuyuki Mase（Applied Chemistry
and Biochemical Engineering Course, Department of Engineering, Graduate School of Integrated

Science and Technology, Shizuoka University）
1P-26

Synthesis of polymer-supported cis-2,4-disubstituted pyrrolidine derivatives and theirapplication to asymmetric reactions
Hidenori Ochiai* 1, Akira Nishiyama 1, Naoki Haraguchi 2, Shinichi Itsuno 2 （ 1 Pharma &Supplemental Nutrition Solutions Vehicle, Kaneka Co., 2 Graduate School of Engineering,
Toyohashi University of Technology）
1P-27

◆

ApplicationofMacroporous

Polystyrene-Triphenylphosphine

MonolithtoPalladium-Catalyzed Cross-Coupling Reaction in Flow System
Hikaru Matsumoto* 1, Yu Hoshino 1, Tomohiro Iwai 2, Masaya Sawamura 2,3, Yoshiko Miura 1（1Department of Chemical Engineering, Kyushu University, 2 Department of Chemistry, Faculty of
Science, Hokkaido University,

3

Institute for Chemical Reaction Design and Discovery(WPI-ICReDD), Hokkaido University）
1P-28

Preparation of Oil-based Stable Sliver Nanoparticle Suspensions

Trong-Ming Don*, Wen-Shan Yang, Tung-Wen Cheng（Department of Chemical and Materials
Engineering, Tamkang University）
1P-29

◆

Design Space Success Stories: Reaction and Crystallization Processes

Leela Christian-Tabak* 1, Hiroaki Tanaka 1, Haitao Zhang 2, Minoru Toshima 1, Mikio Sasaki 1（1Technology Research and Development Divison, Process Research and Development Laboratories,
Sumitomo Dainippon Pharma,

2

Chemical Process Research and Development, Sunovion

Pharmaceuticals）
1P-30

Process development of β―Lactamase inhibitor key intermediate

Masato Murai* 1, Jun Takehara 2, Ryoma Miyake 3, Takanobu Iura 3, Hiroshi Kawabata 3（1 Process
Research & Development Laboratory, Technology Division API Corporation, 2 Functional Organic
Materials Laboratory, Fukuoka R&D Center, Mitsubishi Chemical Corporation, 3 Biotechnology
Laboratory, Science & Innovation Center, Mitsubishi Chemical Corporation）
1P-31

Nitrones with Benzylic Bromides, Zinc, and Isobutyl Nitrite

Kei Yanai*, Hideo Togo（Graduate School of Science, Chiba University）
1P-32

2-Amino-4-arylthiazoles through One-Pot Transformation of Alkylarenes with NBS and

Thioureas
Kaho Shibasaki*, Hideo Togo（Graduate School of Science, Chiba University）
1P-33

Biocatalysts for Hydroxylation

Hiroshi Kadono*, Taiki Nishioka （ Strategic Research Planning Department, Research &Development Division, MicroBiopharm Japan Co., Ltd.）
1P-34

Oxidative Construction of 2-Arylquinolines from β-Arylpropionitriles with Aryllithiumand NIS through Iminyl Radical-mediated Cyclization
Hiroki Naruto*, Hideo Togo（Graduate School of Science, Chiba University）
1P-35

Novel and Practical Deprotection Method of t-Boc Group for Preparation of Cefcapene

Pivoxil Hydrochloride Hydrate Using Formic Acid and Lithium Chloride
Takanori Kurita*, Yoshiko Tanaka, Teruo Iizuka（Chemical Development, Production Technology
Department, Shionogi Pharma Co., Ltd.）
1P-36

The development for manufacturing process of methyl ester reduction with LiBH4

prepared in-situ
Takayuki Toyama*, Naoki Miyake, Yusuke Sato, Takanori Kurita （ Chemical Development,
Production Technology Department, Shionogi Pharma Co., Ltd.）
1P-37

Continuous Flow Lipase-Catalyzed Dynamic Kinetic Resolution of Alcohols

Koichi Higashio* 1, Satoko Katsuragi 1, Franziska Kühn 2, Niklas Adebar 2, Carmen Plass 2, Harald
Gröger 2, Shuji Akai 1（1 Graduate School of Pharmaceutical Sciences, Osaka University, 2 Faculty ofChemistry, Bielefeld University）
1P-38

Chemoselective demethylation of methoxypyridine

Kosho Makino* 1, Yuki Tanaka 1, Yumi Hasegawa 2, Takahide Inoue 1, Koji Araki 2, Hidetsugu
Tabata 2, Tetsuta Oshitari 2, Kiyomi Ito 3, Hideaki Natsugari 4, Hideyo Takahashi 1（1 Faculty of
Pharmaceutical Sciences, Tokyo University of Science, 2 Faculty of Pharma Sciences, Teikyo
University, 3 Research Institute of Pharmaceutical Sciences, Musashino University, 4 Faculty of
Pharmaceutical Sciences, The University of Tokyo）
1P-39

A Case Study of Theoretical Purge Factor for Mutagenic Impurity Management by

Collaboration among 6 Pharmaceutical Companies
Shinji Tamura* 1, Yasufumi Kawanaka 1, Yusuke Nagato 2, Kenichiro Sato* 3, Yosuke Mino 4,
Takashi Watanabe 4, Muneki Kishida 5, Hiroki Ueoka 6, Yu Haranosono 6（1 Ono Pharmaceutical Co.,
Ltd., 2 Fujifilm Corporation, 3 Asahi Kasei Pharma Corporation, 4 Japan Tobacco Inc., 5 Mitsubishi
Tanabe Pharma Corporation, 6 Senju Pharmaceutical Co., Ltd.）
1P-40

Novel

Preparationof Aromatic Nitriles

fromAryl Bromides and Arenes

Imino-nitrogen-centered Radicals.
Ko Uchida*, Hideo Togo（Graduate School of Science, Chiba University）
1P-41

Pd/Cu-catalyzed Anti-Markovnikov Oxidation of Aliphatic Alkenes to Terminal Acetals

viaSaki Komori*, Yoshiko Yamaguchi, Yasutaka Kataoka, Yasuyuki Ura（Department of Chemistry,
Biology, and Environmental Science, Faculty of Science, Nara Women’s University）
1P-42

Heterogeneous Metal Catalyzed Aerobic Dehydrogenative Biaryl Coupling of Aniline

Derivatives
Kenji Matsumoto*, Satoshi Takeda, Yasunori Toubaru, Tsukasa Hirokane, Masahiro Yoshida（Faculty of Pharmaceutical Sciences, Tokushima Bunri University）
1P-43

PAT: Optimize Processes From Liquids to Solids

Yoichi Yamasaki*, Wittkamp Brian, Stephan Woods（AutoChem Business Unit, Mettler-Toledo）
1P-44

Palladium and Niobic Acid on Carbons-Catalyzed Facile Hydrogenative Deprotection of

N-Benzyl Groups
Yuta Yamamoto* 1, Kazuho Ban 1, Yukio Takagi 2, Masatoshi Yoshimura 2, Yoshinari Sawama 1,
Hironao Sajiki 1（1 Laboratory of Organic Chemistry, Gifu Pharmaceutical University, 2 Catalyst
Development Center, N. E. Chemcat Corporation）
1P-45

Pt/C-catalyzed oxidative annulation of diols to Iactones

Ryoya Takakura*, Kazuho Ban, Hironao Sajiki, Yoshinari Sawama （ Gifu Pharmaceutical
University）
1P-46

Aromatic Aldehyde-Selective Functionalization via Pyridinium Salt Intermediates

Takahiro Kawajiri* 1, Hiromichi Fujioka 2, Hironao Sajiki 1, Yoshinari Sawama 1（1 Laboratory ofOrganic Chemistry, Gifu Pharmaceutical University, 2 Graduate School of Pharmaceutical Sciences,
Osaka University）
1P-47

Chiral Macrocyclic Lithium Binaphtholate Catalysts for Enantioselective Addition of

Lithium Acetylides to Ketones
Manabu Hatano*, Kenji Yamashita, Kazuaki Ishihara（Graduate School of Engineering, Nagoya
University）
1P-48

Generation of ynolates via double deprotonation of 2,6-di-tert-butylphenol esters

Jun Sun* 2, Toshiya Yoshiiwa 2, Takayuki Iwata 1, Mitsuru Shindo 1（1 Institute for Materials
Chemistry and Engineering, Kyushu University,

2

Interdisciplinary Graduate School ofEngineering Sciences, Kyushu University）
1P-49

Synthetic Studies of Libraries of Polymers from Half-esters Obtained by Practical Selective

Monohydrolysis of Symmetric Diesters
Satomi Niwayama*, Jianjun Shi（Graduate School of Engineering, Muroran Institute of Technology）

1P-50

Pd/Cu-catalyzed Aerobic Anti-Markovnikov Oxidation of Vinylarenes to Aldehydes andTerminal Acetals
Yasuyuki Ura*, Sonoe Nakaoka, Yuka Murakami, Satoko Matsumura, Ruriko Sato, Wakana
Yokotani, Yasutaka Kataoka（Department of Chemistry, Biology, and Environmental Science,
Faculty of Science, Nara Women’s University）
1P-51

◆

Biocatalytic Process Design – Challenges and Solutions

Stefan Mix*, Gareth Brown, Iain Miskelly（Department of Biocatalysis and Isotope Chemistry,
Almac Group）
1P-52

Hydrosilane-Promoted Facile Deprotection of tert-Butyl Groups in Esters, Ethers,

Carbonates, and Carbamates
Zhenzhong Zhang*, Takuya Ikeda, Yukihiro Motoyama（Department of Advanced Science andTechnology, Toyota Technological Institute）
1P-53

Synthesis of 7-Deazaguanosine Derivatives via Glycosylation

Koki Nakano*, Natsuhisa Oka, Akane Fukuta, Ayumi Mori, Kaori Ando（Department of Chemistry
and Biomolecular Science, Faculty of Engineering, Gifu University）
1P-54

Stereoselective Synthesis of Furanosyl Sulfones and Their Application to Julia-Kocienski

Reaction
Kanna Suzuki*, Natsuhisa Oka, Ayumi Mori, Kaori Ando （ Department of Chemistry and
Biomolecular Science, Faculty of Engineering, Gifu University）
1P-55

One-Step Synthesis of Cyclopentene Derivatives from Julia-Kocienski Reagents Derived

from Nucleosides
Minami Furuzawa*, Natsuhisa Oka, Mayuka Kanda, Kaori Ando（Department of Chemistry and
Biomolecular Science, Faculty of Engineering, Gifu University）
1P-56

Selective Synthesis of Azoxybenzenes from Nitrobenzenes by Photoreduction with Flow

Microreactors
Akira Fujii*, Yasuhiro Nishiyama, Hajime Mori（Industrial Technology Center of Wakayama
Prefecture）
1P-57

Highly efficient synthesisof aromatic

α-keto

acids

from

acetophenones

using

nitrosylsulfuric acid as an oxidant
Tadafumi Matsunaga*, Yasuhiro Kataoka, Shun Tanimura, Masato Kawamura（Health and Crop
Sciences Research Laboratory, Sumitomo Chemical Co., Ltd.）
1P-58

Palladium-catalyzed deoxygenative deuteration of aryl nonaflatesMasami Kuriyama*, Kotaro Tsukuda, Hirotoshi Kiba, Tetsuro Morimoto, Kosuke Yamamoto,
Osamu Onomura（Graduate School of Biomedical Sciences, Nagasaki University）
1P-59

Efficient Synthetic Study of Multi-functionalized Biheteroaromatics by Suzuki Coupling

Masahiro Hamada*, Ryota Fujimoto, Noriyuki Nakajima （ Department of PharmaceuticalEngineering and Biotechnology Research Center, Toyama Prefectural University）
1P-60

Precise Control of the Mutagenic Impurity Production by Flow Synthesis

Masahiro Hosoya*, Takahiro Oshima, Yuki Masuda, Masashi Tanaka, Noriyuki Kurose（API R&DLaboratory, CMC R&D Division, Shionogi & Co., Ltd.）
1P-61

Selective

SynthesisofBenzofuran

Isomers

Using

Rearrangement

ReactionofHydroxychalcone and the Application to Synthesis of Natural ProductYuichiro Ikegami*, Fei Rao, Akira Imamiya, Akira Nakamura, Tomohiro Maegawa（School of
Pharmaceutical Sciences, Kindai University）
1P-62

New Deprotection Method of PMB Protective Group of Alcohols Using Weak Acid in

CF3CH2OH and Remarkable Acceleration of Deprotection of PMB Protected 4-phenylbutanol.
Yugo Kotera*, Misa Matsumura, Hiroko Kawasaki, Norihiko Yamagami, Akira Nakamura,
Tomohiro Maegawa（School of Pharmaceutical Sciences, Kindai University）
1P-63

Design of Novel Halogen Bonding Donors with SF5 and SO2CF3 Functional Groups on

Iodobenzenes
Yuji Sumii*, Kenta Sasaki, Norio Shibata（Department of Life and Applied Chemistry, Nagoya
Institute of Technology）
1P-64

Quick and Continuous Synthesis of Methyl Cinnamates Using a Flow-microwave

Applicator
Hiroki Yoneyama*, Naoki Oka, Megumi Yoshii, Shinya Harusawa, Yoshihide Usami （ Osaka
University of Pharmaceutical Sciences）
1P-65

Utilization of Naturally Occurring Glycosylated Forms for the Synthesis of Flavonoids

Takeshi Sugai*, Ryuji Tsunekawa, Kazuki Kurahayashi, Rie Fujita, Kengo Hanaya, Shuhei
Higashibayashi（Department of Pharmaceutical Sciences, Keio University）
1P-66

13C NMR Spectroscopic Studies of Intra-and Intermolecular Interactions of Amino Acids

and Dipeptide Derivatives in Solutions
Yoshikazu Hiraga 1, Ryosuke Hoshide* 1, Satomi Niwayama 2（1 Graduate School of Science andTechnology, Hiroshima Institute of Technology, 2 Graduate School of Engineering, MuroranInstitute of Technology）

1P-67

SimpleNucleophilesof

Acetamide

Equivalents:

BENAC-K,

PM-BENAC-K,

and

2,4-DM-BENAC-K
Yumika Koike*, Atsunori Hira, Toshiki Tatematsu, Takeo Sakai, Yuji Mori（Faculty of Pharmacy,
Meijo University）
1P-68

Three subjects in Organic Syntheses: Simple, useful, but hitherto inaccessible building

blocksYuichro Ashida*, Takeshi Tsutsumi, Satomi Kajimoto, Hiroshi Nishikado, Hidefumi Nakatsuji, Yoo
Tanabe（Determent of Chemistry, School of Science and Technology, Kwansei Gakuin University）
1P-69

Thermal hazard analysis of self accelerating decomposition via acid production of dimethyl

sulfoxide (DMSO)
Yuto Koizumi* 1, Yu-ichiro Izato 1, Atsumi Miyake 1, Yoshikuni Deguchi 2, Masafumi Kono 3（1Yokohama National University, 2 Kaneka Corporation, 3 Nippon Refine Corporation）
1P-70

In situ analysis of liquid phase oxidation of nitric acid/formic acid mixturesusing thermal and raman spectroscopic analyses
Mahoko Ando*, Michiya Fujita, Yu-ichiro Izato, Atsumi Miyake（Yokohama National University）
1P-71

Efficient Removal of Nitrate Ions Through Calcium Alginate Membrane Immobilizing

Activated Carbon Particles as Adsorbents
Keita Kashima* 1, Kota Teshima 1, Masahide Hagiri 2, Masanao Imai 3（1 Department of Materials
Chemistry and Bioengineering, National Institute of Technology, Oyama College, 2 Department ofMaterials Chemistry and Bioengineering, National Institute of Technology, Fukushima College, 3
Graduate School of Bioresource Sciences, Nihon University）
1P-72

Molecular Separation of Sugars via Calcium Alginate Membrane with Polysaccharide

Network Precisely Controlled Polymeric Structure
Kaito Yosida* 1, Keita Kashima 1, Masanao Imai 2（1 Department of Materials Chemistry andBioengineering, National Institute of Technology, Oyama College, 2 Graduate School of Bioresource
Sciences, Nihon University）
1P-73

Preparation and Characterization of Biocompatible Chitin/Chitosan Membrane Preparedthrough an Acetylation Process of Glucosamine Units
Haruki Koya* 1, Keita Kashima 1, Masanao Imai 2（1 Department of Materials Chemistry andBioengineering, National Institute of Technology, Oyama College, 2 Graduate School of Bioresource
Sciences, Nihon University）
1P-74

Effect of Monomer Composition on the Laccase/O2-Catalyzed Oxidation of Aniline andp-Aminodiphenylamine in the Presence of Anionic Vesicles
Tomoyuki Fujisaki* 1, Keita Kashima 1, Peter Walde 2（1 Department of Materials Chemistry andBioengineering, National Institute of Technology, Oyama College, 2 Department of Materials, ETH
Zurich）
1P-75◆

Application of Highly Efficient Chiral Spiro Catalysts In the Synthesis of Key

Chiral Intermediates of APIs
Yuanqiang Li*, Guoliang Zhu, Pucha Yan（R&D, CDMO unit, Zhejiang Raybow Pharmaceutical Co.
Ltd./ Zhejiang Jiuzhou Pharmaceutical Co., Ltd.）
1P-76

Metal-Free Asymmetric Synthesis of Dihydroquinoxalinones and 4-Imidazolidinones fromα-Amino Acid Precursors via Dehydrogenative N-H/C-H Coupling
Kyalo Stephen Kanyiva* 1, Masashi Horiuchi 2, Marina Tane 2, Takanori Shibata 2（1 Global Centerof Science and Engineering, Advanced School of Science and Engineering, Waseda University, 2
Department of Chemistry and Biochemistry, Advanced School of Science and Engineering, Waseda
University）
1P-77

COF Derived N,P Co-Doped Carbon as a Metal-Free Catalyst for Highly Efficient Oxygen

Reduction Reaction
Chao Yang*, Shinya Maenosono（School of Materials Science, Japan Advanced Institute of Scienceand Technology）
1P-78

Preparation of 1,3-Substituted Pyrroles under Basic Conditions

Kwesi Prah Thomford*, Zheyang Zhou, Yasunori Kama, Keita Kimura, Toshihide Maki（Graduate
School of Biomedical Sciences, Nagasaki University）

July 26th (Fri)
Oral Presentation 13:05-14:20 (Main Hall)
Discussion 14:20-15:30 (Annex Hall)
2P-01◆ Oral Presenter

Ligand-Free Kumada Coupling Catalyzed by Iron(II) Nanoparticle

Yuki Wada* 1, Toshiki Akiyama 1, Tetsuo Honma 2, Yusuke Tamenori 2, Hiromichi Fujioka 1,
Yoshihiro Sato 3, Mitsuhiro Arisawa 1 （ 1 Graduate School of Pharmaceutical Sciences, Osaka
University, 2 Japan Synchrotron Radiation Research Institute, 3 Faculty of Pharmaceutical Sciences,
Hokkaido University）
2P-02

Heterogeneous Palladium on Titania-Catalyzed Ligand-Free Suzuki–Miyaura Coupling ofAryl Chlorides
Hayato Masuda* 1, Tsuyoshi Yamada 1, Kwihwan Park 1, Takumu Tachikawa 1, Tomohiro Ichikawa
1, Masatoshi Yoshimura 2, Yukio Takagi 2, Yoshinari Sawama 1, Hironao Sajiki 1（1 Laboratory ofOrganic Chemistry, Gifu Pharmaceutical University, 2 Catalysts Development Center, N.E.Chemcat
Corporation）
2P-03

Enantioselective

Friedel-Crafts

Alkylation

Reactionof

4,7-DihydroindoletoTrifluoromethylated N-H Ketimines by Means of Chiral Phosphoric Acid
Riku Suzuki*, Masaru Yoshida, Masamichi Miyagawa, Taka hi ko Aki yama（Department ofChemistry, Faculty of Science, Gakushuin University）
2P-04

AJIPHASE®: Practical Oligonucleotide Synthesis Achieved by Solution Phase Approach

Taisuke Ichimaru*, Kunihiro Hirai, Satoshi Inoue, Takuya Hamagaki, Takayuki Hamada, Daisuke
Takahashi（Research Institute For Bioscience Products & Fine Chemicals, AJINOMOTO Co., Inc.）
2P-05

Ion-Pair Extraction of Ammoniums Using Tetracyanocyclopentadienides

Miho Ito*, Naotaka Noda, Chisato Fujimoto, Takeo Sakai, Yuji Mori（Faculty of Pharmacy, Meijo
University）
2P-06

Ultrafast enantiomeric separations using 1.6μm chiral column “CHIRALPAK U series”

Daisuke Fukuda*, Takafumi Onishi, Ryota Hamasaki, Atsushi Ohnishi（Life Science Development
Center, CPI Company, DAICEL Corporation）
2P-07

Orthogonal selectivity controlled by organic bases in arylation for 2-pyridones withdiaryliodonium salts
Yusuke Abe*, Natsumi Hanazawa, Shinpei Ono, Masami Kuriyama, Kosuke Yamamoto, Osamu
Onomura（Graduate School of Biomedical Sciences, Nagasaki University）

2P-08

Total syntheses of all six chiral natural pyrethrins from available synthetic pyrethroids,

directing for process chemistry: accurate determination of the physical properties and insecticidal
activities
Momoyo Kawamoto*, Yuichiro Ashida, Noritada Matsuo, Yoo Tanabe（Department of Chemistry,
School of Science and Technology, Kwansei Gakuin University）
2P-09

Process Development for Large-scale Synthesis of Baloxavir marboxil (Xofluza®)

Nobuaki Fukui* 1, Setsuya Shibahara 1, Toshikatsu Maki 1, Tomohiro Fukuda 1, Kosuke Anan 2,
Takayuki Tsuritani 1（1 API R&D Laboratory, CMC R&D Division, Shionogi & Co., Ltd., 2 Shionogi
Pharmaceutical Research Center, Shionogi & Co., Ltd.）
2P-10

◆

Deacetylative

AminationofAcetylArenesandAlkanesunderTransition-Metal-Free Conditions
Kengo Hyodo* 1, Genna Hasegawa 2, Kingo Uchida 2（1 Department of Chemistry, School of Scienceand Engineering, Kindai University, 2 Department of Materials Chemistry, Faculty of Science andTechnology, Ryukoku University）
2P-11

Application of the Palladium-loaded Monolithic Ion Exchange Resin to a Continuous Flow

Processing
Shinji Nakamura* 1, Hitoshi Takada 1, Tsuyoshi Yamada 2, Yoshinari Sawama 2, Hironao Sajiki 2（1Functional Material Development Department, R&D Center, Organo Co., 2 Laboratory of Organic
Chemistry, Gifu Pharmaceutical University）
2P-12

Development of Boronic Ester-Mediated Ligand-Directed Protein Acylation

Christopher Adamson*, Kenzo Yamatsugu, Motomu Kanai（Department of Pharmaceutical Sciences,
University of Tokyo）
2P-13

C-H γ,γ,γ-Trifluoroalkylation of Quinolines via Visible-light-induced Sequential Radical

Additions
Yuhei Kumagai*, Nanami Murakami, Futa Kamiyama, Ryo Tanaka, Tatsuhiko Yoshino, Masahiro
Kojima, Shigeki Matsunaga（Faculty of Pharmaceutical Sciences, Hokkaido University）
2P-14

Chlorocarbonysulfenyl chlorides: A unique bifunctional electrophilic reagent for thesyntheses of heterocyclic compounds, directing for process chemistry
Masatoshi Kakuno*, Shotaro Izawa, Taichi Takemoto, Yoo Tanabe（Department of Chemistry,
School of Science and Technology, Kwansei Gakuin Univ.）
2P-15

◆

The Catalytic Synthesis of Cyclic Amines from Lactams using Ru-MACHO Family

Osamu Ogata* 1, Hideki Nara 1, Kazuhiko Matsumura 1, Yoshihito Kayaki 2 （ 1 Takasago
International Corporation, 2 Tokyo Institute of Technology）

2P-16

Catalytic asymmetric Mukaiyama aldol addition using 1,3-bis(siloxy)diene promoted by aTi(OiPr)4 / (S)-BINOL catalyst, directed for process chemistry
Takeshi Tsutsumi, Mizuki Moriyama*, Yoo Tanabe（Determent of Chemistry, School of Science andTechnology, Kwansei Gakuin University）
2P-17

Catalytic oxidation reaction for synthesis of triarylmethane blue dyes

Tomoya Okada* 1, Akihiro Nomoto 1, Yuki Yamamoto 1, Mika Yamamoto 1, Michio Ueshima 1, Akiya
Ogawa 1, Tamotsu Nishigahana 2, Keiji Itoh 2, Gohei Kobata 2（1 Department of Applied Chemistry,
Graduate School of Engineering, Osaka Prefecture University, 2 Kobata Sangyo Co., Ltd.）
2P-18

Synthesis of α-exo-Methylene Ketones from α,α-Disubstituted Allyl Alcohols by

Electrochemical Oxidative Migration
Kosuke Yamamoto*, Naoto Kikuchi, Tohru Hamamizu, Hirofumi Yoshimatsu, Masami Kuriyama,
Yosuke Demizu, Osamu Onomura（Graduate School of Biomedical Sciences, Nagasaki University）
2P-19

Metal-free Oxidative Synthesis of Imine Derivatives Catalyzed by Salicylic Acid

Akihiro Nomoto*, Chun Ping Dong, Shintaro Kodama, Michio Ueshima, Akiya Ogawa（Department
of Applied Chemistry, Graduate School of Engineering, Osaka Prefecture University）
2P-20

◆

Autocatalytic Decomposition of Dimethyl Sulfoxide (DMSO)

Yoshikuni Deguchi* 1, Masafumi Kono 2, Yuto Koizumi 3, Yu-ichiro Izato 3, Atsumi Miyake 3（1Kaneka Corporation, 2 Nippon Refine Co. Ltd., 3 Yokohama National University）
2P-21

◆

Development of Vanadium-catalyzed Organic Reactions in Water

Makoto Sako* 1, Nadine Zumbrägel 2, Tomohiro Takiishi 1, Lukas Schober 2, Harald Gröger 2,
Shinobu Takizawa 1, Hiroaki Sasai 1（1 The Institute of Scientific and Industrial Research (ISIR),
Osaka University, 2 Department of Chemistry, Bielefeld University）
2P-22

AI-Assisted Optimization for Synthesis of Spirooxindole Analogues via Enantioselctive

Domino Reaction in Flow System
H. D. P. Wathsala*, Masaru Kondo, Makoto Sako, Yutaro Hanatani, Satoshi Hara, Kazunori
Ishikawa, Takayuki Takaai, Takashi Washio, Shinobu Takizawa, Hiroaki Sasai（The Institute of
Scientific and Industrial Research (ISIR), Osaka University）
2P-23

Development of Composite Materials Comprised of Porphyrin Dyes and Nanocarbons :Effect of Preparation Methods
Yuko Takao*, Kazuyuki Moriwaki, Takumi Mizuno, Toshinobu Ohno（Organic Materials Research
Division, Osaka Municipal Technical Research Institute）

2P-24

Benzylisoquinoline alkaloids production by bacteria for drug discovery

Akira Nakagawa*, Hiromichi Minami（Research Institute for Bioresources and Biotechnology,
Ishikawa Prefectural University）
2P-25

Synthesis of tofogliflozin as an SGLT2 inhibitor via intramolecular cycloaddition

Masatoshi Murakata, Akira Kawase*, Nobuaki Kimura, Takuma Ikeda, Masahiro Nagase,
Masatoshi Koizumi, Kazuaki Kuwata, Kenji Maeda, Hitoshi Shimizu（API Process Development
Department, Chugai Pharmaceutical Co., Ltd.）
2P-26

Strong Base-Catalyzed Hydroamination of Aminoalkenes

Yasutomo Yamamoto*, Maki Terashita, Mio Yamanoue, Masako Yukawa, Akari Miyawaki, Kiyoshi
Tomioka（Faculty of Pharmaceutical Sciences, Doshisha Women’s College of Liberal Arts）
2P-27

◆

Rapid and Practical Synthesis of Fluoren-9-ones Using a Carbon Monoxide

Surrogate
Hideyuki Konishi*, Suguru Futamata, Xi Wang, Kei Manabe（School of Pharmaceutical Sciences,
University of Shizuoka）
2P-28

Activation of Nucleophilic Aromatic Substitution Reaction by Using Silyl Amide Reagent

Takashi Shigeta* 1, Shiho Suzuki 1, Nanomi Murata 2, Yuka Gonno 2, Minoru Ozeki 2, Ikuo
Kawasaki 2, Masahiro Egi 1（1 School of Food and Nutritional Sciences, University of Shizuoka, 2
Graduate School of Pharmaceutical Sciences, Mukogawa Women's University）
2P-29

Chemoselective Transformations of Aromatic Methoxymethyl Ethers Using Trialkylsilyl

Triflate and 2,2’-Bipyridyl
Mizushi Yanagihara*, Reiya Ohta, Kenichi Murai, Mitsuhiro Arisawa, Hiromichi Fujioka（Graduate
School of Pharmaceutical Sciences, Osaka University）
2P-30

Acceptor-controlled Transfer Dehydration of Amides to Nitriles

Asuka Naraoka*, Hiroyuki Okabe, Takahiro Isogawa, Shunsuke Oishi, Hiroshi Naka（Graduate
School of Science, Institute of Transformative Bio-Molecules (WPI-ITbM), and Research Center for
Materials Science, Nagoya University）
2P-31

Hydroperoxide-Mediated Chemoselective, Decarboxylative Acylation of Amine.

Takeshi Nanjo, Natsuki Kato*, Xuan Zhang, Yoshiji Takemoto（Graduate School of Pharmaceutical
Sciences, Kyoto University）
2P-32

Polymorphic Solubility Ratio of Pharmaceutical Drugs in Various Solvents

Yoshihiro Takebayashi*, Kiwamu Sue, Takeshi Furuya, Satoshi Yoda（Research Institute for
Chemical Process Technology, AIST）

2P-33Development of Palladium Phosphine Complexes for the Practical Cross-Coupling

Reactions
Yosuke Imanaka*, Shinji Ueno（Numazu Chemical Catalysts Group, Chemical Catalysts R&D Dept.,
Catalysts Development Center, N.E.Chemcat Corporation）
2P-34

Development of a Synthetic Process for K-8986, an H1-receptor Antagonist

Tomoaki Fukuda* 1,2, Takeaki Hara 1, Shinji Ina 1, Tetsuhiro Nemoto 2, Takeshi Oshima 1（1 Tokyo
New Drug Research Laboratories, Pharmaceutical Division, Kowa Co., LTD., 2 Graduate School of
Pharmaceutical Sciences, Chiba University）
2P-35

Development of gem-Diboronic Acids as Dehydrative Peptide Synthesis Catalysts

Kenichi Michigami*, Tatsuhiko Sakaguchi, Yoshiji Takemoto（Graduate School of Pharmaceutical
Sciences, Kyoto University）
2P-36

A Bulky P-Chiral Phosphine Ligand (BulkyP*): Synthesis and Application in Rh-Catalyzed

Asymmetric Hydrogenation
Yuuki Sawatsugawa*, Ken Tamura, Natsuhiro Sano, Tsuneo Imamoto（Specialty Products R&D
Department, Nippon Chemical Industrial Co., Ltd.）
2P-37

Gas-Liquid Flow Synthesis Using Monolithic Catalysts

Yusuke Saito* 1, Tomohito Mizukami 1, Yushi Nakamura 2, Nobuyuki Mase 2（1 Cataler Corporation,
2 Shizuoka University）

2P-38

Quality by Design (QbD) Approach by Automated Robustness Study to Develop the Design

Space
Kazuhide Konishi*, Sergey Galushko（ChromSword Japan Co., Ltd.）
2P-39

High Quality Peptide APIs from Sophisticated One-Pot Peptide Synthesis AJIPHASE®

Tatsuji Inomata*, Takayoshi Torii, Shin Muronoi, Ryotaro Nakaya, Daisuke Takahashi（ResearchInstitute for Bioscience Products and Fine Chemicals, AJINOMOTO Co., Inc.）
2P-40

Platinum on Carbon Bead-Catalyzed Continuous-Flow Dehydrogenation of 2-Propanol

under Microwave-Irradiation
Tomohiro Ichikawa 1, Takumu Tachikawa* 1, Tomohiro Matsuo 1, Wataru Teranisihi 1, Tsuyoshi
Yamada 1, Yoshinari Sawama 1, Yasunari Monguchi 2, Hironao Sajiki 1（1 Laboratory of Organic
Chemistry, Gifu Pharmaceutical University, 2 Laboratory of Organic Chemistry, Daiichi Universityof Pharmacy）
2P-41

Characterization of chiral column by analyzed of column screening result

Takunori Ueda*, Masahiro Miyamoto, Ryota Hamasaki, Atsushi Ohnishi（Life Science Development
center, CPI Company, DAICEL Corporation）
2P-42

Asymmetric cross-aldol reaction of aldehydes via organocatalyst

Yujiro Hayashi*, Kaito Nagai（Department of Chemistry, Graduate School of Science, Tohoku
University）
2P-43

Atomeconomical Approach to Allylsilanes through Iridium-Catalyzed Hydrosilylation ofAllenes
Ichino Takeuchi*, Shoko Samoto, Yasuyuki Ura, Yasutaka Kataoka（Department of Chemistry,
Biology, and Environmental Science, Faculty of Science, Nara Women’s University）
2P-44

Stable Triazinone-Based Reagent for O-p-Methoxybenzylation under Mild Heating

Conditions
Hikaru Fujita* 1, Hiromitsu Terasaki 1, Satoshi Kakuyama 1, Kazuhito Hioki 2, Munetaka
Kunishima 1（1 Faculty of Pharmaceutical Sciences Institute of Medical, Pharmaceutical, andHealth Sciences, Kanazawa University, 2 Faculty of Pharmaceutical Sciences, Kobe Gakuin
University）
2P-45

Catalytic Regioselective Ring Opening of Epoxides by Unprotected Amines

Yuse Kuriyama*, Yusuke Sasano, Shogo Matsui, Akihito Noguchi, Yoshihiko Hoshino, Shun-ichiro
Uesugi, Yoshiharu Iwabuchi（Graduate School of Pharmaceutical Sciences, Tohoku University）
2P-46

Transition

Metal-Free

One-pot

Synthesisof

3-Benzo[b]thienyl

ThioethersviaBenzo[b]thiophenone
Nanae Habara*, Koichi Mitsudo, Seiji Suga（Division of Applied Chemistry, Graduate School of
Natural Science and Technology, Okayama University）
2P-47

Risks from Rising Temperature

Yoshifumi Fujisawa*, Urs Groth, Fabio Visentin （ AutoChem team, BU LAB Instruments,
Mettler-Toledo K.K.）
2P-48

Mechanistic Analysis in Lithiation-Methylation Reaction of Trifluorobenzoic Acid

Yuya Orito*, Guy C. Lloyd-Jones（Process Technology Research Laboratories, Pharmaceutical
Technology Division, Daiichi-Sankyo Co., Ltd.）
2P-49

The Enhanced Enantio-recognition of Chiral Acylazolium in Kinetic Resolution of Chiral

Secondary Alcohol by Carboxylate Additive
Ken-ichi Yamada*, Yinli Wang, Satoru Kuwano, Tsubasa Inokuma, Yousuke Yamaoka, Kiyosei
Takasu（Graduate School of Pharmaceutical Sciences, Tokushima University）

2P-50◆Synthetic Route Scouting and Process Development of Dolutegravir Sodium

Tatsuro Yasukata*, Yasunori Aoyama（API R&D Laboratory, CMC R&D Division, Shionogi & Co.,
Ltd.）
2P-51

Modernize Synthesis

Naomi Fukuda*（AutoChem Team, BU LAB Instruments, Mettler Toledo K.K.）
2P-52

Photoctalytic N-Methylation of Amino Acids with Methanol

Ivven Huang*, Yuna Morioka, Susumu Saito, Hiroshi Naka（Graduate School of Science andResearch Center for Materials Science, Nagoya University）
2P-53

Platinum on carbon-bead-catalyzed energetically efficient, continuous hydrogen production

method from methylcyclohexane enhanced by the microwave irradiation
Tomohiro Ichikawa* 1, Tomohiro Matsuo 1, Takumu Tachikawa 1, Tsuyoshi Yamada 1, Takeo
Yoshimura 2, Masatoshi Yoshimura 3, Yukio Takagi 3, Yoshinari Sawama 1, Jun-ichi Sugiyama 4,
Yasunari Monguchi 1,5, Hironao Sajiki 1（1 Laboratory of Organic Chemistry, Gifu Pharmaceutical
University, 2 SAIDA FDS Incorporated, 3 Catalyst Development, N.E.Chemcat Corporation, 4
National Institute of Advanced Industrial Science and Technology, 5 Laboratory of Organic
Chemistry, Daiichi University of Pharmacy）
2P-54

One-pot Preparation of α,β-Unsaturated Aldehydes by Julia-Kocienski Reaction andHydrolysis
Haruka Watanabe*, Zhu Xiaoxian, Kaori Ando（Department of Chemistry and Biomolecular Science,
Faculty of Engineering, Gifu University）
2P-55

Enhanced Development and Control of Continuous Processes Using Real-Time In Situ

FTIR－What’s Happening in Your Flow Chemistry?
Yuki Hara*, Brian Wittkamp（LAB Instruments Business Unit, Mettler-Toledo）
2P-56

Expansion of Substrate Scope of Nitroxyl Radical/Copper-Catalyzed Aerobic Alcohol

Oxidation
Yusuke Sasano, Ryota Sasaki*, Koki Kasabata, Naoki Kogure, Shota Nagasawa, Yoshiharu
Iwabuchi（Graduate School of Pharmaceutical Sciences, Tohoku University）
2P-57

Palladium-Catalyzed Reaction of Silyl-Substituted Allyl Acetates with Water Proceeding

through 1,2-Shift of a Substituent on Silyl Group
Yoshikazu Horino, Mayo Ishibashi*, Kosuke Nakasai, Hitoshi Abe（Graduate School of Science andEngineering, University of Toyama）

2P-58

Scale-up Synthesis of Icatibant using Molecular Hiving Technology

Daisuke Kubo* 1, Kazuaki Kanai 1, Rino Araki 1, Yu Ito 1, Natsumi Iwanaga 1, Kousuke Suzuki 1,
Hideaki Suzuki 1, Ichiro Shima 1, Takashi Yamasaki 1, Yohei Okada 2, Hidehiro Kamiya 2, Kazuhiro
Chiba 2（1 JITSUBO Co., Ltd., Life Science Research Center, 2 Tokyo University of Agriculture andTechnology）
2P-59

One-pot Preparation of Julia-Kocienski Sulfides and Sulfones from Alcohols

Kaori Ando*, Junichiro Hattori（Department of Chemistry and Biomolecular Science, Faculty ofEngineering, Gifu University）
2P-60

Rapid Removal and Release ability of DualPore Metal Scavenger in High Flow System

Riichi Miyamoto* 1, Hong-zhi Bai 1, Makoto Tsujisaka 2, Yoshiki Sohrin 2（1 DPS Inc., 2 Institute for
Chemical Research, Kyoto University）
2P-61

Synthesis of Aryl and Heteroaryl Tetrafluoro-λ6-sulfanyl Chlorides

Kiyoteru Niina* 1, Ibrayim Saidalimu 1, Yumeng Liang 1, Kazuhiro Tanagawa 1,Norimichi Saito 2,
Norio Shibata 1（1 Department of Nanopharmaceutical Sciences and Department of Life Science andApplied Chemistry Nagoya Institute of Technology, 2 Pharmaceutical Division, Ube Industries, Ltd.）
2P-62

Ab initio modeling for Michael addition reaction of acrylic acid

Michiya Fujita* 1, Yu-ichiro Izato 1, Atsumi Miyake 2（1 Graduate School of Environment andinformation Sciences/ 2 Institute of Advanced Sciences, Yokohama National University）
2P-63

Attractive reaction yield on hydrolysis of phospholipid by immobilized phospholipase A1

with hydrophobic porous carrier
Yusuke Hayakawa* 1, Ryoichi Nakayama 2, Norikazu Namiki 2, Masanao Imai 1（1 Course in
Bioresource Utilization Sciences, Graduate School of Bioresource Sciences, Nihon University, 2
Department of Environmental Chemistry & Chemical Engineering, School of Advanced
Engineering, Kogakuin University）
2P-64

Catalyst-free Decarboxylatiave functionalization of Lithium Pyridylacetate

Ryouta Kawanishi*, Lacksany Phongphane, Kosuke Nakada, Seiji Iwasa, Kazutaka Shibatomi（Department of Applied Chemistry and Life Science, Toyohashi University of Technology）
2P-65

◆

Synthetic Strategy for Process Optimization of a PDE10A Inhibitor Consisting of

Pyrazolopyrimidine and Quinoxaline as Key Units
Takafumi Yamagami*, Noriaki Moriyama, Eiji Toyofuku, Hideki Horiuchi, Shinichi Izumoto, Ryo
Kobayashi（Mitsubishi Tanabe Pharma Corporation）
2P-66

Nucleophilic C2-arylation of quinolines using diaryliodonium salts

Tatsuya Sugiyama*, Kosuke Yamamoto, Masami Kuriyama, Osamu Onomura（Graduate School of
Biomedical Sciences, Nagasaki University）
2P-67

Preparation of Diaryl Ether Using Ullmann Reaction and Its Application to Ellagitannin

Synthesis
Haruka Imai*, Kazuma Shioe, Yoshiyasu Kato, Daichi Ogura, Yoshikazu Horino, Hitoshi Abe（Graduate School of Innovative Life Science, University of Toyama）
2P-68

Investigation of Purity Determination of Hygroscopic Compound using qNMR

Hiroo Sugawara*, Toru Miura, Yoshiaki Iwamoto（Functional Materials Research Laboratories,
FUJIFILM Wako Pure Chemical Corporation.）
2P-69

Regioselective Formylation of Pyrrole Derivatives with Crystalline Vilsmeier reagent

Takuya Warashina*, Daisuke Matsuura, Yoshikazu Kimura（Research & Development department,
Iharanikkei Chemical Industry Co., Ltd.）
2P-70

Development of multi-functional NHC catalysts bearing pyridine moiety: Application tocatalytic asymmetric reactions
Takahiro Soeta*, Yuichi Hatanaka, So Mizuno, Yutaka Ukaji（Division of Material Chemistry,
Graduate School of Natural Science and Technology, Kanazawa University）
2P-71

Synthesis of Ethynyl Benziodoxolone (EBX)−Acetonitrile Complex and Reaction with

Sulfonamide
Daisuke Shimbo*, Masaharu Yudasaka, Norihiro Tada, Eiji Yamaguchi, Akichika Itoh （ Gifu
Pharmaceutical University）
2P-72

Divergent and scalable synthesis of β-amino acid analogues by catalytic enantioselective

addition of glyoxylate cyanohydrin to imines
Xuan Zhang, Yusuke Tokuhiro*, Takeshi Nanjo, Yoshiji Takemoto （ Graduate School of
Pharmaceutical Sciences, Kyoto University）
2P-73

Developmental Research of Ynamides Synthesis Method Using Copper Catalyst andHypervalent Iodine Compounds
Ryogo Takai*, Norihiro Tada, Eiji Yamaguchi, Akichika Itoh（Gifu Pharmaceutical Univercity）
2P-74

Synthetic Study of Total Synthesis of Sigillin A

Yousuke Yamaoka*, Takamori Nakayama, Syota Kawai, Hiroshi Takikawa, Kiyosei Takasu（Graduate School and Faculty of Pharmaceutical Sciences, Kyoto University）
2P-75

KHMDS-Promoted Enolate–Olefin Metathesis

Kiyosei Takasu, Kazuma Sugimoto*, Shun Fujimura, Ken-ichi Yamada, Hiroshi Takikawa, Yousuke
Yamaoka（Graduate School of Pharmaceutical Sciences, Kyoto University）
2P-76

Assessment of 4-Methyltetrahydropyran (4-MeTHP) as an Organic Reaction Solvent

Tomoki Tamura*, Takashi Kawakami, Saki Yoshimoto, Araki Masuyama, Shoji Kobayashi（Graduate School of Engineering, Osaka Institute of Technology）
2P-77

Preparation of carboxymethyl cellulose, calcium alginate and chitosan membrane involved

with mechanical strength
Tomohiro Nakata*, Masanao Imai（Course in Bioresource Utilization Sciences, Graduate School of
Bioresource Sciences, Nihon University）