Conforms to US OSHA Hazard Communication 29CFR1910.1200

SAFETY DATA SHEET
Seahorse XFp T Cell Metabolic Profiling Kit

Section 1. Identification
1.1 Product identifier
Product name: Seahorse XFp T Cell Metabolic Profiling Kit

Part no. (chemical kit)

: 103771-100

Part no.

: XFp oligomycin A
Not available.
XFp Bam15
Not available.
XFp Rot/AA
Not available.
Validation date
: 6/10/2024
1.2 Relevant identified uses of the substance or mixture and uses advised against
Identified uses
: For research use only.

Uses advised against

XFp oligomycin A
XFp Bam15
XFp Rot/AA: Not for use in diagnostic procedures (RUO).

6 x 3.544 mg
6 x 14.463 mg
6 x 3.493 mg

1.3 Details of the supplier of the safety data sheet
Supplier/Manufacturer: Agilent Technologies, Inc.
5301 Stevens Creek Blvd
Santa Clara, CA 95051, USA
800-227-9770

1.4 Emergency telephone number
In case of emergency: CHEMTREC®: 1-800-424-9300

Section 2. Hazards identification
2.1 Classification of the substance or mixture
OSHA/HCS status: XFp oligomycin A

XFp Bam15

XFp Rot/AA

While this material is not considered hazardous by the
OSHA Hazard Communication Standard (29 CFR
1910.1200), this SDS contains valuable information
critical to the safe handling and proper use of the product.
This SDS should be retained and available for employees
and other users of this product.
While this material is not considered hazardous by the
OSHA Hazard Communication Standard (29 CFR
1910.1200), this SDS contains valuable information
critical to the safe handling and proper use of the product.
This SDS should be retained and available for employees
and other users of this product.
This material is considered hazardous by the OSHA
Hazard Communication Standard (29 CFR 1910.1200).

Classification of the substance or mixture
XFp Rot/AA
H400
AQUATIC HAZARD (ACUTE) - Category 1
H410
AQUATIC HAZARD (LONG-TERM) - Category 1
2.2 GHS label elements

Date of issue :06/10/2024

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Seahorse XFp T Cell Metabolic Profiling Kit

Section 2. Hazards identification
Hazard pictograms: XFp Rot/AA

Signal word

: XFp oligomycin A
XFp Bam15
XFp Rot/AA: XFp oligomycin A
XFp Bam15
XFp Rot/AA

No signal word.
No signal word.
Warning
No known significant effects or critical hazards.
No known significant effects or critical hazards.
H410 - Very toxic to aquatic life with long lasting
effects.

: XFp oligomycin A
XFp Bam15
XFp Rot/AA: XFp oligomycin A
XFp Bam15
XFp Rot/AA: XFp oligomycin A
XFp Bam15
XFp Rot/AA: XFp oligomycin A
XFp Bam15
XFp Rot/AA

Not applicable.
Not applicable.
P273 - Avoid release to the environment.
Not applicable.
Not applicable.
P391 - Collect spillage.
Not applicable.
Not applicable.
Not applicable.

Hazard statements

Precautionary statements
Prevention

Response

Storage

Disposal

Supplemental label
elements: XFp oligomycin A
XFp Bam15
XFp Rot/AA

Not applicable.
Not applicable.
P501 - Dispose of contents and container inaccordance with all local, regional, national andinternational regulations.
None known.
None known.
None known.

: XFp oligomycin A
XFp Bam15
XFp Rot/AA

None known.
None known.
None known.

2.3 Other hazards
Hazards not otherwiseclassified

Section 3. Composition/information on ingredients
Substance/mixture: XFp oligomycin A
XFp Bam15
XFp Rot/AA

Ingredient name

MixtureMixtureMixture%CAS number

Antimycin A≤0.1

1397-94-0(2R,6aS,12aS)-1,2,6,6a,12,12a-hexahydro-2-isopropenyl8,9-dimethoxychromeno[3,4-b]furo[2,3-h]chromen-6-one≤0.1

83-79-4

XFp Rot/AA

Any concentration shown as a range is to protect confidentiality or is due to batch variation.
There are no additional ingredients present which, within the current knowledge of the supplier and in theconcentrations applicable, are classified and hence require reporting in this section.
Occupational exposure limits, if available, are listed in Section 8.

Date of issue :06/10/2024

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Seahorse XFp T Cell Metabolic Profiling Kit

Section 4. First aid measures
4.1 Description of necessary first aid measures
Eye contact: XFp oligomycin A

XFp Bam15

XFp Rot/AA

Inhalation: XFp oligomycin A
XFp Bam15
XFp Rot/AA

Skin contact: XFp oligomycin A
XFp Bam15
XFp Rot/AA

Ingestion: XFp oligomycin A

XFp Bam15

XFp Rot/AA

Immediately flush eyes with plenty of water,
occasionally lifting the upper and lower eyelids.
Check for and remove any contact lenses. Get
medical attention if irritation occurs.
Immediately flush eyes with plenty of water,
occasionally lifting the upper and lower eyelids.
Check for and remove any contact lenses. Get
medical attention if irritation occurs.
Immediately flush eyes with plenty of water,
occasionally lifting the upper and lower eyelids.
Check for and remove any contact lenses. Get
medical attention if irritation occurs.
Remove victim to fresh air and keep at rest in aposition comfortable for breathing. Get medical
attention if symptoms occur.
Remove victim to fresh air and keep at rest in aposition comfortable for breathing. Get medical
attention if symptoms occur.
Remove victim to fresh air and keep at rest in aposition comfortable for breathing.
Flush contaminated skin with plenty of water.
Remove contaminated clothing and shoes. Get
medical attention if symptoms occur.
Flush contaminated skin with plenty of water.
Remove contaminated clothing and shoes. Get
medical attention if symptoms occur.
Flush contaminated skin with plenty of water.
Remove contaminated clothing and shoes. Get
medical attention if symptoms occur.
Wash out mouth with water. If material has beenswallowed and the exposed person is conscious,
give small quantities of water to drink. Do not
induce vomiting unless directed to do so by medical
personnel. Get medical attention if symptoms
occur.
Wash out mouth with water. If material has beenswallowed and the exposed person is conscious,
give small quantities of water to drink. Do not
induce vomiting unless directed to do so by medical
personnel. Get medical attention if symptoms
occur.
Wash out mouth with water. If material has beenswallowed and the exposed person is conscious,
give small quantities of water to drink. Do not
induce vomiting unless directed to do so by medical
personnel.

4.2 Most important symptoms/effects, acute and delayed
Potential acute health effects
Eye contact

Inhalation

Date of issue :: XFp oligomycin A
XFp Bam15
XFp Rot/AA: XFp oligomycin A
XFp Bam15
XFp Rot/AA
06/10/2024

No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
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Seahorse XFp T Cell Metabolic Profiling Kit

Section 4. First aid measures
Skin contact: XFp oligomycin A
XFp Bam15
XFp Rot/AA
Ingestion: XFp oligomycin A
XFp Bam15
XFp Rot/AA
Over-exposure signs/symptoms

No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.

Eye contact: XFp oligomycin A
XFp Bam15
XFp Rot/AA: XFp oligomycin A
XFp Bam15
XFp Rot/AA: XFp oligomycin A
XFp Bam15
XFp Rot/AA

No specific data.
No specific data.
No specific data.
No specific data.
No specific data.
No specific data.
No specific data.
No specific data.
No specific data.

: XFp oligomycin A
XFp Bam15
XFp Rot/AA

No specific data.
No specific data.
No specific data.

Inhalation

Skin contact

Ingestion

4.3 Indication of immediate medical attention and special treatment needed, if necessary
Notes to physician: XFp oligomycin A
XFp Bam15
XFp Rot/AA

Specific treatments

Protection of first-aiders: XFp oligomycin A
XFp Bam15
XFp Rot/AA: XFp oligomycin A
XFp Bam15
XFp Rot/AA

Treat symptomatically. Contact poison treatment
specialist immediately if large quantities have been
ingested or inhaled.
Treat symptomatically. Contact poison treatment
specialist immediately if large quantities have been
ingested or inhaled.
Treat symptomatically. Contact poison treatment
specialist immediately if large quantities have been
ingested or inhaled.
No specific treatment.
No specific treatment.
No specific treatment.
No action shall be taken involving any personal risk
or without suitable training.
No action shall be taken involving any personal risk
or without suitable training.
No action shall be taken involving any personal risk
or without suitable training.

See toxicological information (Section 11)

Section 5. Fire-fighting measures
5.1 Extinguishing media
Suitable extinguishingmedia: XFp oligomycin A
XFp Bam15
XFp Rot/AA

Unsuitable extinguishing
media

Date of issue :: XFp oligomycin A
XFp Bam15
XFp Rot/AA

06/10/2024

Use an extinguishing agent suitable for thesurrounding fire.
Use an extinguishing agent suitable for thesurrounding fire.
Use an extinguishing agent suitable for thesurrounding fire.
None known.
None known.
None known.

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Seahorse XFp T Cell Metabolic Profiling Kit

Section 5. Fire-fighting measures
5.2 Special hazards arising from the substance or mixture
Specific hazards arisingfrom the chemical: XFp oligomycin A
XFp Bam15
XFp Rot/AA

Hazardous thermal
decomposition products: XFp oligomycin A

XFp Bam15

XFp Rot/AA

No specific fire or explosion hazard.
No specific fire or explosion hazard.
This material is very toxic to aquatic life with long
lasting effects. Fire water contaminated with thismaterial must be contained and prevented frombeing discharged to any waterway, sewer or drain.
Decomposition products may include the following
materials:
halogenated compounds
metal oxide/oxides
Decomposition products may include the following
materials:
halogenated compounds
metal oxide/oxides
Decomposition products may include the following
materials:
halogenated compounds
metal oxide/oxides

5.3 Advice for firefighters
Special protective actions
for fire-fighters: XFp oligomycin A

XFp Bam15

XFp Rot/AA

Special protective
equipment for fire-fighters: XFp oligomycin A

XFp Bam15

XFp Rot/AA

Promptly isolate the scene by removing all persons
from the vicinity of the incident if there is a fire. No
action shall be taken involving any personal risk orwithout suitable training.
Promptly isolate the scene by removing all persons
from the vicinity of the incident if there is a fire. No
action shall be taken involving any personal risk orwithout suitable training.
Promptly isolate the scene by removing all persons
from the vicinity of the incident if there is a fire. No
action shall be taken involving any personal risk orwithout suitable training.
Fire-fighters should wear appropriate protective
equipment and self-contained breathing apparatus(SCBA) with a full face-piece operated in positive
pressure mode.
Fire-fighters should wear appropriate protective
equipment and self-contained breathing apparatus(SCBA) with a full face-piece operated in positive
pressure mode.
Fire-fighters should wear appropriate protective
equipment and self-contained breathing apparatus(SCBA) with a full face-piece operated in positive
pressure mode.

Section 6. Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures
For non-emergency
personnel: XFp oligomycin A

XFp Bam15

Date of issue :06/10/2024

No action shall be taken involving any personalrisk or without suitable training. Evacuatesurrounding areas. Keep unnecessary andunprotected personnel from entering. Do nottouch or walk through spilled material. Put on
appropriate personal protective equipment.
No action shall be taken involving any personalrisk or without suitable training. Evacuatesurrounding areas. Keep unnecessary andunprotected personnel from entering. Do not
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Section 6. Accidental release measures
XFp Rot/AA

For emergency responders : XFp oligomycin A

XFp Bam15

XFp Rot/AA

6.2 Environmental
precautions: XFp oligomycin A

XFp Bam15

XFp Rot/AA

touch or walk through spilled material. Put on
appropriate personal protective equipment.
No action shall be taken involving any personalrisk or without suitable training. Evacuatesurrounding areas. Keep unnecessary andunprotected personnel from entering. Do nottouch or walk through spilled material. Put on
appropriate personal protective equipment.
If specialized clothing is required to deal with thespillage, take note of any information in Section 8
on suitable and unsuitable materials. See also
the information in "For non-emergency personnel".
If specialized clothing is required to deal with thespillage, take note of any information in Section 8
on suitable and unsuitable materials. See also
the information in "For non-emergency personnel".
If specialized clothing is required to deal with thespillage, take note of any information in Section 8
on suitable and unsuitable materials. See also
the information in "For non-emergency personnel".
Avoid dispersal of spilled material and runoff andcontact with soil, waterways, drains and sewers.
Inform the relevant authorities if the product hascaused environmental pollution (sewers,
waterways, soil or air).
Avoid dispersal of spilled material and runoff andcontact with soil, waterways, drains and sewers.
Inform the relevant authorities if the product hascaused environmental pollution (sewers,
waterways, soil or air).
Avoid dispersal of spilled material and runoff andcontact with soil, waterways, drains and sewers.
Inform the relevant authorities if the product hascaused environmental pollution (sewers,
waterways, soil or air). Water polluting material.
May be harmful to the environment if released inlarge quantities. Collect spillage.

6.3 Methods and materials for containment and cleaning up
Methods for cleaning up: XFp oligomycin A

XFp Bam15

XFp Rot/AA

Date of issue :06/10/2024

Move containers from spill area. Vacuum or sweep
up material and place in a designated, labeledwaste container. Dispose of via a licensed waste
disposal contractor.
Move containers from spill area. Vacuum or sweep
up material and place in a designated, labeledwaste container. Dispose of via a licensed waste
disposal contractor.
Move containers from spill area. Vacuum or sweep
up material and place in a designated, labeledwaste container. Dispose of via a licensed waste
disposal contractor.

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Section 7. Handling and storage
7.1 Precautions for safe handlingProtective measures: XFp oligomycin A
XFp Bam15
XFp Rot/AA

Advice on general
occupational hygiene: XFp oligomycin A

XFp Bam15

XFp Rot/AA

7.2 Conditions for safe
storage, including any
incompatibilities: XFp oligomycin A

XFp Bam15

Date of issue :06/10/2024

Put on appropriate personal protective equipment(see Section 8).
Put on appropriate personal protective equipment(see Section 8).
Put on appropriate personal protective equipment(see Section 8). Do not ingest. Avoid contact witheyes, skin and clothing. Avoid release to theenvironment. Keep in the original container or an
approved alternative made from a compatible
material, kept tightly closed when not in use.
Empty containers retain product residue and can be
hazardous. Do not reuse container.
Eating, drinking and smoking should be prohibitedin areas where this material is handled, stored andprocessed. Workers should wash hands and face
before eating, drinking and smoking. Remove
contaminated clothing and protective equipment
before entering eating areas. See also Section 8
for additional information on hygiene measures.
Eating, drinking and smoking should be prohibitedin areas where this material is handled, stored andprocessed. Workers should wash hands and face
before eating, drinking and smoking. Remove
contaminated clothing and protective equipment
before entering eating areas. See also Section 8
for additional information on hygiene measures.
Eating, drinking and smoking should be prohibitedin areas where this material is handled, stored andprocessed. Workers should wash hands and face
before eating, drinking and smoking. Remove
contaminated clothing and protective equipment
before entering eating areas. See also Section 8
for additional information on hygiene measures.
Storage temperature: room temperature. Store inaccordance with local regulations. Store in originalcontainer protected from direct sunlight in a dry,cool and well-ventilated area, away fromincompatible materials (see Section 10) and foodand drink. Keep container tightly closed and sealed
until ready for use. Containers that have been
opened must be carefully resealed and kept uprightto prevent leakage. Do not store in unlabeledcontainers. Use appropriate containment to avoid
environmental contamination. See Section 10 forincompatible materials before handling or use.
Storage temperature: room temperature. Store inaccordance with local regulations. Store in originalcontainer protected from direct sunlight in a dry,cool and well-ventilated area, away fromincompatible materials (see Section 10) and foodand drink. Keep container tightly closed and sealed
until ready for use. Containers that have been
opened must be carefully resealed and kept uprightto prevent leakage. Do not store in unlabeledcontainers. Use appropriate containment to avoid
environmental contamination. See Section 10 forincompatible materials before handling or use.
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Section 7. Handling and storage
XFp Rot/AA

Storage temperature: room temperature. Store inaccordance with local regulations. Store in originalcontainer protected from direct sunlight in a dry,cool and well-ventilated area, away fromincompatible materials (see Section 10) and foodand drink. Keep container tightly closed and sealed
until ready for use. Containers that have been
opened must be carefully resealed and kept uprightto prevent leakage. Do not store in unlabeledcontainers. Use appropriate containment to avoid
environmental contamination. See Section 10 forincompatible materials before handling or use.

7.3 Specific end use(s)Recommendations

Industrial sector specificsolutions: XFp oligomycin A
XFp Bam15
XFp Rot/AA: XFp oligomycin A
XFp Bam15
XFp Rot/AA

Industrial applications, Professional applications.
Industrial applications, Professional applications.
Industrial applications, Professional applications.
Not available.
Not available.
Not available.

Section 8. Exposure controls/personal protection
8.1 Control parameters
Occupational exposure limits
Ingredient name

Exposure limits

XFp Rot/AA
Antimycin A(2R,6aS,12aS)-1,2,6,6a,12,12a-hexahydro-2-isopropenyl8,9-dimethoxychromeno[3,4-b]furo[2,3-h]chromen-6-one

None.
ACGIH TLV (United States, 1/2024).
TWA: 5 mg/m³ 8 hours.
OSHA PEL 1989 (United States, 3/1989).
TWA: 5 mg/m³ 8 hours.
NIOSH REL (United States, 10/2020).
TWA: 5 mg/m³ 10 hours.
OSHA PEL (United States, 5/2018).
TWA: 5 mg/m³ 8 hours.
CAL OSHA PEL (United States, 5/2018).
TWA: 5 mg/m³ 8 hours.

Biological exposure indices
No exposure indices known.
8.2 Exposure controls
Appropriate engineering
controls: Good general ventilation should be sufficient to control worker exposure to airborne
contaminants.

Environmental exposure
controls: Emissions from ventilation or work process equipment should be checked to ensure
they comply with the requirements of environmental protection legislation. In somecases, fume scrubbers, filters or engineering modifications to the process equipment
will be necessary to reduce emissions to acceptable levels.

Individual protection measures

Date of issue :06/10/2024

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Section 8. Exposure controls/personal protection
Hygiene measures: Wash hands, forearms and face thoroughly after handling chemical products, before
eating, smoking and using the lavatory and at the end of the working period.
Appropriate techniques should be used to remove potentially contaminated clothing.
Wash contaminated clothing before reusing. Ensure that eyewash stations and safety
showers are close to the workstation location.
: Safety eyewear complying with an approved standard should be used when a risk
assessment indicates this is necessary to avoid exposure to liquid splashes, mists,gases or dusts. If contact is possible, the following protection should be worn, unlessthe assessment indicates a higher degree of protection: safety glasses with sideshields.

Eye/face protection

Skin protection
Hand protection

Body protection

Other skin protection

Respiratory protection: Chemical-resistant, impervious gloves complying with an approved standard should beworn at all times when handling chemical products if a risk assessment indicates this isnecessary. Considering the parameters specified by the glove manufacturer, check
during use that the gloves are still retaining their protective properties. It should be
noted that the time to breakthrough for any glove material may be different for different
glove manufacturers. In the case of mixtures, consisting of several substances, theprotection time of the gloves cannot be accurately estimated.
: Personal protective equipment for the body should be selected based on the task being
performed and the risks involved and should be approved by a specialist before
handling this product.
: Appropriate footwear and any additional skin protection measures should be selectedbased on the task being performed and the risks involved and should be approved by aspecialist before handling this product.
: Based on the hazard and potential for exposure, select a respirator that meets theappropriate standard or certification. Respirators must be used according to a
respiratory protection program to ensure proper fitting, training, and other important
aspects of use.

Section 9. Physical and chemical properties and safety characteristics
The conditions of measurement of all properties are at standard temperature and pressure unless otherwise indicated.
Appearance
Physical state: XFp oligomycin A
XFp Bam15
XFp Rot/AA

Solid.
Solid.
Solid.

Color: XFp oligomycin A
XFp Bam15
XFp Rot/AA: XFp oligomycin A
XFp Bam15
XFp Rot/AA: XFp oligomycin A
XFp Bam15
XFp Rot/AA

Not available.
Not available.
Not available.
Not available.
Not available.
Not available.
Not available.
Not available.
Not available.

: XFp oligomycin A
XFp Bam15
XFp Rot/AA: XFp oligomycin A
XFp Bam15
XFp Rot/AA: XFp oligomycin A
XFp Bam15
XFp Rot/AA

Not available.
Not available.
Not available.
Not available.
Not available.
Not available.
Not available.
Not available.
Not available.

Odor

Odor threshold

pH

Melting point/freezing point

Boiling point, initial boilingpoint, and boiling range

Date of issue :06/10/2024

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Section 9. Physical and chemical properties and safety characteristics
Flash point

Evaporation rate

Flammability

Lower and upper explosion
limit/flammability limit
Vapor pressure
Relative vapor density

Relative density

Solubility(ies)
Partition coefficient: noctanol/water
Auto-ignition temperature
Decomposition temperature

Viscosity: XFp oligomycin A
XFp Bam15
XFp Rot/AA: XFp oligomycin A
XFp Bam15
XFp Rot/AA: XFp oligomycin A
XFp Bam15
XFp Rot/AA

Not applicable.
Not applicable.
Not applicable.
Not available.
Not available.
Not available.
Not available.
Not available.
Not available.

: XFp oligomycin A
XFp Bam15
XFp Rot/AA: Not available.
: XFp oligomycin A
XFp Bam15
XFp Rot/AA: XFp oligomycin A
XFp Bam15
XFp Rot/AA: Not available.

Not applicable.
Not applicable.
Not applicable.

: XFp oligomycin A
XFp Bam15
XFp Rot/AA: XFp oligomycin A
XFp Bam15
XFp Rot/AA: XFp oligomycin A
XFp Bam15
XFp Rot/AA: XFp oligomycin A
XFp Bam15
XFp Rot/AA

Not applicable.
Not applicable.
Not applicable.
Not applicable.
Not applicable.
Not applicable.
Not available.
Not available.
Not available.
Not applicable.
Not applicable.
Not applicable.

: XFp oligomycin A
XFp Bam15
XFp Rot/AA

Not available.
Not available.
Not available.

Not applicable.
Not applicable.
Not applicable.
Not available.
Not available.
Not available.

Particle characteristics
Median particle size

Section 10. Stability and reactivity
10.1 Reactivity: XFp oligomycin A
XFp Bam15
XFp Rot/AA

10.2 Chemical stability

Date of issue :: XFp oligomycin A
XFp Bam15
XFp Rot/AA

06/10/2024

No specific test data related to reactivity available
for this product or its ingredients.
No specific test data related to reactivity available
for this product or its ingredients.
No specific test data related to reactivity available
for this product or its ingredients.
The product is stable.
The product is stable.
The product is stable.

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Section 10. Stability and reactivity
10.3 Possibility ofhazardous reactions: XFp oligomycin A

Under normal conditions of storage and use,hazardous reactions will not occur.
Under normal conditions of storage and use,hazardous reactions will not occur.
Under normal conditions of storage and use,hazardous reactions will not occur.

XFp Bam15
XFp Rot/AA

10.4 Conditions to avoid: XFp oligomycin A
XFp Bam15
XFp Rot/AA

No specific data.
No specific data.
No specific data.

10.5 Incompatible materials: XFp oligomycin A

May react or be incompatible with oxidizing
materials.
May react or be incompatible with oxidizing
materials.
May react or be incompatible with oxidizing
materials.

XFp Bam15
XFp Rot/AA

10.6 Hazardous
decomposition products: XFp oligomycin A

Under normal conditions of storage and use,hazardous decomposition products should not be
produced.
Under normal conditions of storage and use,hazardous decomposition products should not be
produced.
Under normal conditions of storage and use,hazardous decomposition products should not be
produced.

XFp Bam15
XFp Rot/AA

Section 11. Toxicological information
11.1 Information on toxicological effects
Acute toxicity
Product/ingredient name
XFp Rot/AA
Antimycin A(2R,6aS,12aS)-1,2,6,6a,
12,12a-hexahydro2-isopropenyl8,9-dimethoxychromeno[3,4-b]furo[2,3-h]chromen6-one

ResultSpecies

Dose

Exposure

LD50 Oral
LD50 Oral

Rat
Rat

28 mg/kg
25 mg/kg-

Irritation/Corrosion
Product/ingredient name
XFp Rot/AA(2R,6aS,12aS)-1,2,6,6a,
12,12a-hexahydro2-isopropenyl8,9-dimethoxychromeno[3,4-b]furo[2,3-h]chromen6-one

ResultSpecies

Score

Exposure

Observation

Eyes - Mild irritant

Rabbit-1%-

Sensitization
Not available.
Mutagenicity
Conclusion/Summary
Date of issue :: Not available.

06/10/2024

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Section 11. Toxicological information
Carcinogenicity
Conclusion/Summary: Not available.

Reproductive toxicity
Conclusion/Summary: Not available.

Teratogenicity
Conclusion/Summary: Not available.

Specific target organ toxicity (single exposure)
Name

Category

Route ofexposure

Target organs

XFp Rot/AA(2R,6aS,12aS)-1,2,6,6a,12,12a-hexahydro-2-isopropenyl8,9-dimethoxychromeno[3,4-b]furo[2,3-h]chromen-6-one

Category 3-

Respiratory tract
irritation
Narcotic effects

Category 3
Specific target organ toxicity (repeated exposure)
Not available.
Aspiration hazard
Not available.
Information on the likely
routes of exposure: XFp oligomycin A
XFp Bam15
XFp Rot/AA

Potential acute health effects
Eye contact: XFp oligomycin A
XFp Bam15
XFp Rot/AA
Inhalation: XFp oligomycin A
XFp Bam15
XFp Rot/AA
Skin contact: XFp oligomycin A
XFp Bam15
XFp Rot/AA
Ingestion: XFp oligomycin A
XFp Bam15
XFp Rot/AA

Not available.
Not available.
Not available.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.

Symptoms related to the physical, chemical and toxicological characteristics
Eye contact: XFp oligomycin A
No specific data.
XFp Bam15
No specific data.
XFp Rot/AA
No specific data.
Inhalation: XFp oligomycin A
No specific data.
XFp Bam15
No specific data.
XFp Rot/AA
No specific data.
Skin contact: XFp oligomycin A
No specific data.
XFp Bam15
No specific data.
XFp Rot/AA
No specific data.
Ingestion: XFp oligomycin A
No specific data.
XFp Bam15
No specific data.
XFp Rot/AA
No specific data.
Delayed and immediate effects and also chronic effects from short and long term exposure
Short term exposure
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Section 11. Toxicological information
Potential immediate
effects: Not available.

Potential delayed effects: Not available.

Long term exposure
Potential immediate
effects: Not available.

Potential delayed effects: Not available.

Potential chronic health effects
General: XFp oligomycin A
XFp Bam15
XFp Rot/AA
Carcinogenicity: XFp oligomycin A
XFp Bam15
XFp Rot/AA
Mutagenicity: XFp oligomycin A
XFp Bam15
XFp Rot/AA
Reproductive toxicity: XFp oligomycin A
XFp Bam15
XFp Rot/AA

No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.

Numerical measures of toxicity
Acute toxicity estimates
Product/ingredient name

Oral (mg/kg)

Dermal(mg/kg)Inhalation Inhalation(gases)(vapors)(ppm)(mg/l)

Inhalation(dusts andmists) (mg/l)

XFp oligomycin A
XFp oligomycin A

101101.6

N/A

N/A

N/A

N/A

XFp Bam15
XFp Bam15

99003.0

N/A

N/A

N/A

N/A

99020.6
28
25

N/A
N/A
N/A

N/A
N/A
N/A

N/A
N/A
N/A

N/A
N/A
N/A

XFp Rot/AA
XFp Rot/AA
Antimycin A(2R,6aS,12aS)-1,2,6,6a,12,12a-hexahydro2-isopropenyl-8,9-dimethoxychromeno[3,4-b]furo[2,3-h]chromen-6-one

Section 12. Ecological information
12.1 Toxicity
Product/ingredient name
XFp Rot/AA
Antimycin A(2R,6aS,12aS)-1,2,6,6a,
12,12a-hexahydro2-isopropenyl8,9-dimethoxychromeno[3,4-b]furo[2,3-h]chromen6-one
Date of issue :ResultSpecies

Exposure

Acute LC50 0.000019 mg/l Fresh water
Acute EC50 190 µg/l Fresh water

Fish - Oncorhynchus mykiss
Crustaceans - Simocephalus
serrulatus - Larvae

96 hours
48 hours

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Section 12. Ecological information
Acute EC50 3.7 µg/l Fresh water
Acute LC50 1.9 ppb Fresh water
Chronic NOEC 0.3 ppb Fresh water
Chronic NOEC 1.01 ppb

Daphnia - Daphnia magna
Fish - Oncorhynchus mykiss
Daphnia - Daphnia magna
Fish - Oncorhynchus mykiss

48 hours
96 hours
21 days
32 days12.2 Persistence and degradability
Not available.
12.3 Bioaccumulative potential
Product/ingredient name
XFp Rot/AA(2R,6aS,12aS)-1,2,6,6a,
12,12a-hexahydro2-isopropenyl8,9-dimethoxychromeno[3,4-b]furo[2,3-h]chromen6-one

LogPow

BCF

Potential

4.1

25.7

Low

12.4 Mobility in soil
Soil/water partition
coefficient (KOC): Not available.

12.5 Other adverse effects: No known significant effects or critical hazards.

Section 13. Disposal considerations
13.1 Waste treatment methods
Disposal methods: The generation of waste should be avoided or minimized wherever possible. Disposal ofthis product, solutions and any by-products should at all times comply with therequirements of environmental protection and waste disposal legislation and any regional
local authority requirements. Dispose of surplus and non-recyclable products via alicensed waste disposal contractor. Waste should not be disposed of untreated to thesewer unless fully compliant with the requirements of all authorities with jurisdiction.
Waste packaging should be recycled. Incineration or landfill should only be consideredwhen recycling is not feasible. This material and its container must be disposed of in asafe way. Care should be taken when handling emptied containers that have not beencleaned or rinsed out. Empty containers or liners may retain some product residues.
Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains
and sewers.
Disposal should be in accordance with applicable regional, national and local laws and regulations. Local
regulations may be more stringent than regional or national requirements.
The information presented below only applies to the material as supplied. The identification based on
characteristic(s) or listing may not apply if the material has been used or otherwise contaminated. It is the
responsibility of the waste generator to determine the toxicity and physical properties of the material generated todetermine the proper waste identification and disposal methods in compliance with applicable regulations.
Refer to Section 7: HANDLING AND STORAGE and Section 8: EXPOSURE CONTROLS/PERSONAL PROTECTION
for additional handling information and protection of employees.

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Section 14. Transport information
DOT / TDG / Mexico / IMDG / : Not regulated.
IATA
Additional information
Remarks: De minimis quantities
Special precautions for user : Transport within user’s premises: always transport in closed containers that are
upright and secure. Ensure that persons transporting the product know what to do in theevent of an accident or spillage.
Transport in bulk according
to IMO instruments: Not available.

Section 15. Regulatory information
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture
U.S. Federal regulations: TSCA 8(a) CDR Exempt/Partial exemption: Not determined
Clean Water Act (CWA) 311: Nitric acid, iron(3+) salt, nonahydrate

Clean Air Act Section 112(b) Hazardous Air
Pollutants (HAPs): Not listed

Clean Air Act Section 602
Class I Substances: Not listed

Clean Air Act Section 602
Class II Substances: Not listed

DEA List I Chemicals(Precursor Chemicals): Not listed

DEA List II Chemicals(Essential Chemicals): Not listed

SARA 302/304
Composition/information on ingredients
SARA 302 TPQ

SARA 304 RQ

Name

%

EHS

(lbs)

(gallons)(lbs)(gallons)

XFp Rot/AA
Antimycin A

≤0.1

Yes.

1000 /
10000

-

1000

-

SARA 304 RQ: 6946099 lbs / 3153528.9 kg

SARA 311/312: XFp oligomycin A

Classification

XFp Bam15
XFp Rot/AA

Not applicable.
Not applicable.
Not applicable.

Composition/information on ingredients
No products were found.
State regulations
Massachusetts: None of the components are listed.

New York: None of the components are listed.

New Jersey: None of the components are listed.

Pennsylvania: None of the components are listed.

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Section 15. Regulatory information
California Prop. 65
This product does not require a Safe Harbor warning under California Prop. 65.
International regulations
Chemical Weapon Convention List Schedules I, II & III Chemicals
Not listed.
Montreal Protocol
Not listed.
Stockholm Convention on Persistent Organic Pollutants
Not listed.
Rotterdam Convention on Prior Informed Consent (PIC)
Not listed.
UNECE Aarhus Protocol on POPs and Heavy Metals
Not listed.
Inventory list
Australia: Not determined.

Canada: Not determined.

China: Not determined.

Japan
New Zealand: Japan inventory (CSCL): Not determined.
Japan inventory (ISHL): Not determined.
: Not determined.

Philippines: Not determined.

Republic of Korea: Not determined.

Taiwan: Not determined.

Thailand: Not determined.

Turkey: Not determined.

United States: Not determined.

Viet Nam: Not determined.

Section 16. Other information
Procedure used to derive the classification
Classification
XFp Rot/AA
AQUATIC HAZARD (ACUTE) - Category 1
AQUATIC HAZARD (LONG-TERM) - Category 1

Justification
Calculation method
Calculation method

History
Date of issue/Date ofrevision
Date of previous issue: 06/10/2024

Version: 2

Key to abbreviations: ATE = Acute Toxicity Estimate
BCF = Bioconcentration Factor
GHS = Globally Harmonized System of Classification and Labelling of Chemicals
IATA = International Air Transport Association
IBC = Intermediate Bulk Container
IMDG = International Maritime Dangerous Goods
LogPow = logarithm of the octanol/water partition coefficient

Date of issue :: 06/29/2021

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Section 16. Other information
MARPOL = International Convention for the Prevention of Pollution From Ships, 1973
as modified by the Protocol of 1978. ("Marpol" = marine pollution)
N/A = Not available
UN = United Nations
Indicates information that has changed from previously issued version.
Notice to reader
Disclaimer: The information contained in this document is based on Agilent’s state of knowledge at the time of
preparation. No warranty as to its accurateness, completeness or suitability for a particular purpose is expressedor implied.

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