SAFETY DATA SHEET
according to the OSHA Hazard Communication Standard

Mianserin Formulation
Version
3.8

Revision Date:
09/30/2023

SDS Number:
1601083-00012

Date of last issue: 04/04/2023
Date of first issue: 05/01/2017

SECTION 1. IDENTIFICATION
Product name:

Mianserin Formulation

Manufacturer or supplier's details
Company name of supplier: Organon & Co.
Address: 30 Hudson Street, 33nd floor
Jersey City, New Jersey, U.S.A 07302
Telephone: 1-551-430-6000
Emergency telephone: 1-215-631-6999
E-mail address: EHSSTEWARD@organon.com
Recommended use of the chemical and restrictions on use
Recommended use: Pharmaceutical
Restrictions on use: Not applicable
SECTION 2. HAZARDS IDENTIFICATIONGHS classification in accordance with the OSHA Hazard Communication Standard (29 CFR
1910.1200)
Reproductive toxicity: Category 2
Specific target organ toxicity- single exposure:

Category 1 (Central nervous system)

GHS label elements
Hazard pictograms:

Signal Word:

DangerHazard Statements:

H361fd Suspected of damaging fertility. Suspected of damaging
the unborn child.
H370 Causes damage to organs (Central nervous system).

Precautionary Statements:

Prevention:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been readand understood.
P260 Do not breathe dust, fume, gas, mist, vapors or spray.
P264 Wash skin thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves, protective clothing, eye protection
and face protection.
Response:
P307 + P311 IF exposed: Call a doctor.
Storage:
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SAFETY DATA SHEET
according to the OSHA Hazard Communication Standard

Mianserin Formulation
Version
3.8

Revision Date:
09/30/2023

SDS Number:
1601083-00012

Date of last issue: 04/04/2023
Date of first issue: 05/01/2017

P405 Store locked up.
Disposal:
P501 Dispose of contents and container to an approved waste
disposal plant.
Other hazards
None known.
SECTION 3. COMPOSITION/INFORMATION ON INGREDIENTS
Substance / Mixture:

MixtureComponents
Chemical name
CAS-No.
mianserin hydrochloride
21535-47-7
Starch
9005-25-8
Silica71187-19-4
Actual concentration is withheld as a trade secretConcentration (% w/w)>= 10 - < 20>= 10 - < 20>= 1 - < 5

SECTION 4. FIRST AID MEASURES
General advice:

In the case of accident or if you feel unwell, seek medical
advice immediately.
When symptoms persist or in all cases of doubt seek medical
advice.

If inhaled:

In case of skin contact:

In case of eye contact:

If swallowed:

Most important symptoms
and effects, both acute anddelayedProtection of first-aiders:

Notes to physician:

If inhaled, remove to fresh air.
Get medical attention.
In case of contact, immediately flush skin with soap and plentyof water.
Remove contaminated clothing and shoes.
Get medical attention.
Wash clothing before reuse.
Thoroughly clean shoes before reuse.
Flush eyes with water as a precaution.
Get medical attention if irritation develops and persists.
If swallowed, DO NOT induce vomiting.
Get medical attention.
Rinse mouth thoroughly with water.
Never give anything by mouth to an unconscious person.
Suspected of damaging fertility. Suspected of damaging theunborn child.
Causes damage to organs.
First Aid responders should pay attention to self-protection,and use the recommended personal protective equipment
when the potential for exposure exists (see section 8).
Treat symptomatically and supportively.

:

SECTION 5. FIRE-FIGHTING MEASURES
Suitable extinguishing media:

Water spray
Alcohol-resistant foam
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SAFETY DATA SHEET
according to the OSHA Hazard Communication Standard

Mianserin Formulation
Version
3.8

Revision Date:
09/30/2023

SDS Number:
1601083-00012

Date of last issue: 04/04/2023
Date of first issue: 05/01/2017

Unsuitable extinguishingmedia
Specific hazards during firefighting
Hazardous combustion products:

Carbon dioxide (CO2)
Dry chemical
None known.

:

Exposure to combustion products may be a hazard to health.

:

Carbon oxides
Metal oxides
Oxides of phosphorus
Silicon oxides

Specific extinguishing methods:

Special protective equipment
for fire-fighters:

Use extinguishing measures that are appropriate to local circumstances and the surrounding environment.
Use water spray to cool unopened containers.
Remove undamaged containers from fire area if it is safe to doso.
Evacuate area.
In the event of fire, wear self-contained breathing apparatus.
Use personal protective equipment.

SECTION 6. ACCIDENTAL RELEASE MEASURES
Personal precautions, protec- :tive equipment and emergency procedures

Use personal protective equipment.
Follow safe handling advice (see section 7) and personal
protective equipment recommendations (see section 8).

Environmental precautions:

Avoid release to the environment.
Prevent further leakage or spillage if safe to do so.
Retain and dispose of contaminated wash water.
Local authorities should be advised if significant spillages
cannot be contained.

Methods and materials forcontainment and cleaning up:

Surround spill with absorbents and place a damp coveringover the area to minimize entry of the material into the air.
Add excess liquid to allow the material to enter into solution.
Soak up with inert absorbent material.
Clean up remaining materials from spill with suitable
absorbent.
Local or national regulations may apply to releases anddisposal of this material, as well as those materials and items
employed in the cleanup of releases. You will need todetermine which regulations are applicable.
Sections 13 and 15 of this SDS provide information regarding
certain local or national requirements.

SECTION 7. HANDLING AND STORAGE
Technical measures:

Local/Total ventilation
Advice on safe handling::

See Engineering measures under EXPOSURE
CONTROLS/PERSONAL PROTECTION section.
Use only with adequate ventilation.
Do not breathe dust, fume, gas, mist, vapors or spray.
Do not swallow.
Avoid contact with eyes.
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SAFETY DATA SHEET
according to the OSHA Hazard Communication Standard

Mianserin Formulation
Version
3.8

Revision Date:
09/30/2023

SDS Number:
1601083-00012

Conditions for safe storage:

Materials to avoid:

Date of last issue: 04/04/2023
Date of first issue: 05/01/2017

Avoid prolonged or repeated contact with skin.
Wash skin thoroughly after handling.
Handle in accordance with good industrial hygiene and safety
practice, based on the results of the workplace exposure
assessment
Do not eat, drink or smoke when using this product.
Take care to prevent spills, waste and minimize release to theenvironment.
Keep in properly labeled containers.
Store locked up.
Store in accordance with the particular national regulations.
Do not store with the following product types:
Strong oxidizing agents
Self-reactive substances and mixtures
Organic peroxides
Explosives
Gases

SECTION 8. EXPOSURE CONTROLS/PERSONAL PROTECTION
Ingredients with workplace control parameters
Components

CAS-No.

Value type
(Form ofexposure)
21535-47-7
TWA
Further information: Skin
Wipe limit
9005-25-8
TWA
TWA (Respirable)
TWA (total)
TWA (total
dust)
TWA (respirable fraction)
71187-19-4
TWA (Dust)

mianserin hydrochloride

StarchSilicaTWA (Dust)

TWA

Engineering measures:

Control parameters / Permissible
concentration
20 µg/m3 (OEB 3)

Basis

200 µg/100 cm²
10 mg/m³
5 mg/m³

Internal
ACGIH
NIOSH REL

10 mg/m³
15 mg/m³

NIOSH REL
OSHA Z-1

5 mg/m³

OSHA Z-1

20 Million
particles per cubic
foot(Silica)
80 mg/m3/ %SiO2(Silica)
6 mg/m³(Silica)

OSHA Z-3

Internal

OSHA Z-3

NIOSH REL

Ensure adequate ventilation, especially in confined areas.
Minimize workplace exposure concentrations.

Personal protective equipment
Respiratory protection: General and local exhaust ventilation is recommended tomaintain vapor exposures below recommended limits. Where
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SAFETY DATA SHEET
according to the OSHA Hazard Communication Standard

Mianserin Formulation
Version
3.8

Revision Date:
09/30/2023

SDS Number:
1601083-00012

Date of last issue: 04/04/2023
Date of first issue: 05/01/2017

concentrations are above recommended limits or are
unknown, appropriate respiratory protection should be worn.
Follow OSHA respirator regulations (29 CFR 1910.134) anduse NIOSH/MSHA approved respirators. Protection provided
by air purifying respirators against exposure to any
hazardous chemical is limited. Use a positive pressure air
supplied respirator if there is any potential for uncontrolled
release, exposure levels are unknown, or any othercircumstance where air purifying respirators may not provide
adequate protection.
Hand protection
Material:

Chemical-resistant gloves

Remarks:

Eye protection:

Skin and body protection:

Hygiene measures:

Choose gloves to protect hands against chemicals dependingon the concentration specific to place of work. Breakthroughtime is not determined for the product. Change gloves often!
For special applications, we recommend clarifying theresistance to chemicals of the aforementioned protective
gloves with the glove manufacturer. Wash hands before
breaks and at the end of workday.
Wear the following personal protective equipment:
Safety glasses
Select appropriate protective clothing based on chemical
resistance data and an assessment of the local exposure
potential.
Skin contact must be avoided by using impervious protective
clothing (gloves, aprons, boots, etc).
If exposure to chemical is likely during typical use, provide
eye flushing systems and safety showers close to theworking place.
When using do not eat, drink or smoke.
Wash contaminated clothing before re-use.

SECTION 9. PHYSICAL AND CHEMICAL PROPERTIES
Appearance:

Crystalline solid

Color

:

white to off-white

Odor

:

No data available

Odor Threshold:

No data available

pH:

No data available

Melting point/freezing point:

No data available

Initial boiling point and boiling
range

:

No data available

Flash point:

Not applicable

Evaporation rate:

No data available
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SAFETY DATA SHEET
according to the OSHA Hazard Communication Standard

Mianserin Formulation
Version
3.8

Revision Date:
09/30/2023

SDS Number:
1601083-00012

Date of last issue: 04/04/2023
Date of first issue: 05/01/2017

Flammability (solid, gas):

Not classified as a flammability hazard

Flammability (liquids):

No data available

Upper explosion limit / Upper
flammability limit:

No data available

Lower explosion limit / Lower
flammability limit:

No data available

Vapor pressure:

No data available

Relative vapor density:

No data available

Relative density:

No data available

Density:

No data available

Solubility(ies)
Water solubility:

No data available

Partition coefficient: noctanol/water
Autoignition temperature:

No data available:

No data available

Decomposition temperature:

No data available

Viscosity
Viscosity, kinematic:

No data available

Explosive properties:

Not explosive

Oxidizing properties:

The substance or mixture is not classified as oxidizing.

Molecular weight:Not applicable

Particle size:

No data available

SECTION 10. STABILITY AND REACTIVITY
Reactivity
Chemical stability
Possibility of hazardous reactions
Conditions to avoid
Incompatible materials
Hazardous decomposition
products:::

Not classified as a reactivity hazard.
Stable under normal conditions.
Can react with strong oxidizing agents.

:::

None known.
Oxidizing agents
No hazardous decomposition products are known.

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SAFETY DATA SHEET
according to the OSHA Hazard Communication Standard

Mianserin Formulation
Version
3.8

Revision Date:
09/30/2023

SDS Number:
1601083-00012

Date of last issue: 04/04/2023
Date of first issue: 05/01/2017

SECTION 11. TOXICOLOGICAL INFORMATION
Information on likely routes of exposure
Skin contact
Ingestion
Eye contact
Acute toxicity
Not classified based on available information.
Product:
Acute oral toxicity:

Acute toxicity estimate: > 5,000 mg/kg
Method: Calculation method:

LD50 (Rat): 780 mg/kg

Components:
mianserin hydrochloride:
Acute oral toxicity

LD50 (Mouse): 224 mg/kg
Acute toxicity (other routes of :administration)

LD50 (Mouse): 32 mg/kg
Application Route: Intravenous

Starch:Acute oral toxicity:

LD50 (Rat): > 5,000 mg/kg

Acute dermal toxicity:

LD50 (Rabbit): > 2,000 mg/kg

Silica:Acute oral toxicity:

LD50 (Rat): > 5,000 mg/kg
Remarks: Based on data from similar materials

Skin corrosion/irritation
Not classified based on available information.
Components:
mianserin hydrochloride:
Remarks:

Not classified due to lack of data.

Silica:ResultRemarks::

No skin irritation
Based on data from similar materials

Serious eye damage/eye irritation
Not classified based on available information.

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SAFETY DATA SHEET
according to the OSHA Hazard Communication Standard

Mianserin Formulation
Version
3.8

Revision Date:
09/30/2023

SDS Number:
1601083-00012

Date of last issue: 04/04/2023
Date of first issue: 05/01/2017

Components:
mianserin hydrochloride:
Remarks:

Not classified due to lack of data.

Starch:SpeciesResult::RabbitNo eye irritation

Silica:SpeciesResult
MethodRemarks::::

RabbitNo eye irritation
Draize Test
Based on data from similar materials

Respiratory or skin sensitization
Skin sensitization
Not classified based on available information.
Respiratory sensitization
Not classified based on available information.
Components:
mianserin hydrochloride:
Remarks:

Not classified due to lack of data.

Starch:Test Type
Routes of exposure
SpeciesResult::::Maximization Test
Skin contact
Guinea pig
negative

Germ cell mutagenicity
Not classified based on available information.
Components:
mianserin hydrochloride:
Genotoxicity in vitro:

Test Type: gene mutation test
Result: positive
Test Type: Bacterial reverse mutation assay (AMES)
Result: negative
Remarks: Based on data from similar materials
Test Type: sister chromatid exchange assay
Result: negative
Remarks: Based on data from similar materials

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SAFETY DATA SHEET
according to the OSHA Hazard Communication Standard

Mianserin Formulation
Version
3.8

Revision Date:
09/30/2023

SDS Number:
1601083-00012

Date of last issue: 04/04/2023
Date of first issue: 05/01/2017

Test Type: In vitro mammalian cell gene mutation test
Result: negative
Remarks: Based on data from similar materials
Test Type: unscheduled DNA synthesis assay
Result: negative
Remarks: Based on data from similar materials
Genotoxicity in vivo:

Test Type: Micronucleus test
Species: Rat
Cell type: Bone marrow
Application Route: Oral
Result: negative
Remarks: Based on data from similar materials

Starch:Genotoxicity in vitro:

Test Type: Bacterial reverse mutation assay (AMES)
Result: negative

Silica:Genotoxicity in vitro:

Test Type: Bacterial reverse mutation assay (AMES)
Result: negative
Remarks: Based on data from similar materials

Carcinogenicity
Not classified based on available information.
Components:
mianserin hydrochloride:
Remarks:

Not classified due to lack of data.

IARC

No ingredient of this product present at levels greater than or equal to 0.1% isidentified as probable, possible or confirmed human carcinogen by IARC.

OSHA

No component of this product present at levels greater than or equal to 0.1% is
on OSHA’s list of regulated carcinogens.

NTP

No ingredient of this product present at levels greater than or equal to 0.1% isidentified as a known or anticipated carcinogen by NTP.

Reproductive toxicity
Suspected of damaging fertility. Suspected of damaging the unborn child.
Components:
mianserin hydrochloride:
Effects on fertility:

Test Type: Fertility
Species: Rat, maleFertility: NOAEL: 100 mg/kg body weight
Result: No effects on fertility., No effects on mating
performance.
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SAFETY DATA SHEET
according to the OSHA Hazard Communication Standard

Mianserin Formulation
Version
3.8

Revision Date:
09/30/2023

SDS Number:
1601083-00012

Date of last issue: 04/04/2023
Date of first issue: 05/01/2017

Test Type: Fertility
Species: Rat, female
Fertility: LOAEL: 30 mg/kg body weight
Result: Preimplantation loss., ovarian dysfunction, Effect on
estrous cycle
Effects on fetal development:

Test Type: Development
Species: Rat
Application Route: Subcutaneous
Developmental Toxicity: LOAEL: 10 mg/kg body weight
Result: Effects on postnatal development.
Test Type: Development
Species: Rat
Developmental Toxicity: LOAEL: 3 mg/kg body weight
Result: Embryolethal effects., No teratogenic effects.
Test Type: Development
Species: Rabbit
Result: Reduced fetal weight., No teratogenic effects.
Test Type: Development
Species: Mouse
Developmental Toxicity: NOAEL: 30 mg/kg body weight
Result: No effects on fetal development.

Reproductive toxicity - Assessment:

Suspected of damaging fertility. Suspected of damaging theunborn child.

STOT-single exposure
Causes damage to organs (Central nervous system).
Components:
mianserin hydrochloride:
Target Organs
Assessment::

Central nervous system
Causes damage to organs.

STOT-repeated exposure
Not classified based on available information.
Repeated dose toxicity
Components:
mianserin hydrochloride:
Species
NOAEL
Application RouteExposure time
Remarks

:
:
:
:
:

Rat
30 mg/kg
Oral
6 Months
No significant adverse effects were reported

Species:Dog
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SAFETY DATA SHEET
according to the OSHA Hazard Communication Standard

Mianserin Formulation
Version
3.8

Revision Date:
09/30/2023

SDS Number:
1601083-00012

Date of last issue: 04/04/2023
Date of first issue: 05/01/2017

LOAEL
Application RouteExposure time
Symptoms::::

3 - 30 mg/kg
Oral
6 Months
Reduced body weight

Starch:Species
NOAEL
Application RouteExposure time
Method

:
:
:
:
:

Rat
>= 2,000 mg/kg
Skin contact
28 Days
OECD Test Guideline 410

Aspiration toxicity
Not classified based on available information.
Experience with human exposure
Components:
mianserin hydrochloride:
Inhalation:

Skin contact:

Eye contact
Ingestion::

Remarks: May be harmful if inhaled.
May cause irritation of respiratory tract.
Remarks: Can be absorbed through skin.
May irritate skin.
Remarks: May irritate eyes.
Symptoms: central nervous system effects, dry mouth, constipation, Headache, Tremors

SECTION 12. ECOLOGICAL INFORMATION
Ecotoxicity
Components:
Silica:Toxicity to fish

Toxicity to algae/aquaticplants:LC50 (Brachydanio rerio (zebrafish)): > 10,000 mg/l
Exposure time: 96 h
Method: OECD Test Guideline 203
Remarks: Based on data from similar materials:

EC50: > 10,000 mg/l
Exposure time: 72 h
Method: OECD Test Guideline 201
Remarks: Based on data from similar materials

Persistence and degradability
No data available
Bioaccumulative potential
Components:
mianserin hydrochloride:
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SAFETY DATA SHEET
according to the OSHA Hazard Communication Standard

Mianserin Formulation
Version
3.8

Revision Date:
09/30/2023

Partition coefficient: noctanol/water

SDS Number:
1601083-00012:

Date of last issue: 04/04/2023
Date of first issue: 05/01/2017

log Pow: 3.36

Mobility in soil
No data available
Other adverse effects
No data available
SECTION 13. DISPOSAL CONSIDERATIONS
Disposal methods
Waste from residues:

Contaminated packaging:

Dispose of in accordance with local regulations.
Do not dispose of waste into sewer.
Empty containers should be taken to an approved waste
handling site for recycling or disposal.
If not otherwise specified: Dispose of as unused product.

SECTION 14. TRANSPORT INFORMATIONInternational Regulations
UNRTDG
Not regulated as a dangerous good
IATA-DGR
Not regulated as a dangerous good
IMDG-CodeNot regulated as a dangerous goodTransport in bulk according to Annex II of MARPOL 73/78 and the IBC CodeNot applicable for product as supplied.
Domestic regulation
49 CFR
Not regulated as a dangerous goodSpecial precautions for user
Not applicable
SECTION 15. REGULATORY INFORMATIONCERCLA Reportable Quantity
This material does not contain any components with a CERCLA RQ.
SARA 304 Extremely Hazardous Substances Reportable Quantity
This material does not contain any components with a section 304 EHS RQ.
SARA 302 Extremely Hazardous Substances Threshold Planning Quantity
This material does not contain any components with a section 302 EHS TPQ.
SARA 311/312 Hazards:

Reproductive toxicity
Specific target organ toxicity (single or repeated exposure)
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SAFETY DATA SHEET
according to the OSHA Hazard Communication Standard

Mianserin Formulation
Version
3.8

Revision Date:
09/30/2023

SDS Number:
1601083-00012

SARA 313:

Date of last issue: 04/04/2023
Date of first issue: 05/01/2017

This material does not contain any chemical components withknown CAS numbers that exceed the threshold (De Minimis)
reporting levels established by SARA Title III, Section 313.

US State Regulations
Pennsylvania Right To Know
Calcium hydrogenorthophosphate dihydrate
Starchmianserin hydrochloride

7789-77-7
9005-25-821535-47-7

California Permissible Exposure Limits for Chemical Contaminants
StarchSilica9005-25-8
71187-19-4

The ingredients of this product are reported in the following inventories:
AICS: not determinedDSL:

not determined

IECSC

:

not determined

SECTION 16. OTHER INFORMATION
Further information
NFPA 704:

HMIS® IV:
Flammability

HEALTH1
Health00Special hazard*

4

FLAMMABILITY

1

PHYSICAL HAZARD

0

Instability

HMIS® ratings are based on a 0-4 rating
scale, with 0 representing minimal hazards or risks, and 4 representing significant hazards or risks. The "*" represents
a chronic hazard, while the "/" represents
the absence of a chronic hazard.

Full text of other abbreviations
ACGIH: USA. ACGIH Threshold Limit Values (TLV)
NIOSH REL
: USA. NIOSH Recommended Exposure Limits
OSHA Z-1: USA. Occupational Exposure Limits (OSHA) - Table Z-1 Limits for Air Contaminants
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SAFETY DATA SHEET
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Mianserin Formulation
Version
3.8

Revision Date:
09/30/2023

SDS Number:
1601083-00012

OSHA Z-3:

ACGIH / TWA
NIOSH REL / TWA::

OSHA Z-1 / TWA
OSHA Z-3 / TWA::

Date of last issue: 04/04/2023
Date of first issue: 05/01/2017

USA. Occupational Exposure Limits (OSHA) - Table Z-3 Mineral Dusts
8-hour, time-weighted averageTime-weighted average concentration for up to a 10-hour
workday during a 40-hour workweek
8-hour time weighted average
8-hour time weighted average

AIIC - Australian Inventory of Industrial Chemicals; ASTM - American Society for the Testing ofMaterials; bw - Body weight; CERCLA - Comprehensive Environmental Response, Compensation,and Liability Act; CMR - Carcinogen, Mutagen or Reproductive Toxicant; DIN - Standard of theGerman Institute for Standardisation; DOT - Department of Transportation; DSL - Domestic Substances List (Canada); ECx - Concentration associated with x% response; EHS - Extremely Hazardous Substance; ELx - Loading rate associated with x% response; EmS - Emergency Schedule;
ENCS - Existing and New Chemical Substances (Japan); ErCx - Concentration associated with
x% growth rate response; ERG - Emergency Response Guide; GHS - Globally Harmonized System; GLP - Good Laboratory Practice; HMIS - Hazardous Materials Identification System; IARC International Agency for Research on Cancer; IATA - International Air Transport Association; IBC- International Code for the Construction and Equipment of Ships carrying Dangerous Chemicals
in Bulk; IC50 - Half maximal inhibitory concentration; ICAO - International Civil Aviation Organization; IECSC - Inventory of Existing Chemical Substances in China; IMDG - International Maritime
Dangerous Goods; IMO - International Maritime Organization; ISHL - Industrial Safety and Health
Law (Japan); ISO - International Organisation for Standardization; KECI - Korea Existing Chemicals Inventory; LC50 - Lethal Concentration to 50 % of a test population; LD50 - Lethal Dose to
50% of a test population (Median Lethal Dose); MARPOL - International Convention for the Prevention of Pollution from Ships; MSHA - Mine Safety and Health Administration; n.o.s. - Not Otherwise Specified; NFPA - National Fire Protection Association; NO(A)EC - No Observed (Adverse)
Effect Concentration; NO(A)EL - No Observed (Adverse) Effect Level; NOELR - No Observable
Effect Loading Rate; NTP - National Toxicology Program; NZIoC - New Zealand Inventory ofChemicals; OECD - Organization for Economic Co-operation and Development; OPPTS - Officeof Chemical Safety and Pollution Prevention; PBT - Persistent, Bioaccumulative and Toxic substance; PICCS - Philippines Inventory of Chemicals and Chemical Substances; (Q)SAR - (Quantitative) Structure Activity Relationship; RCRA - Resource Conservation and Recovery Act;REACH - Regulation (EC) No 1907/2006 of the European Parliament and of the Council concerning the Registration, Evaluation, Authorisation and Restriction of Chemicals; RQ - Reportable
Quantity; SADT - Self-Accelerating Decomposition Temperature; SARA - Superfund Amendments and Reauthorization Act; SDS - Safety Data Sheet; TCSI - Taiwan Chemical SubstanceInventory; TECI - Thailand Existing Chemicals Inventory; TSCA - Toxic Substances Control Act(United States); UN - United Nations; UNRTDG - United Nations Recommendations on theTransport of Dangerous Goods; vPvB - Very Persistent and Very Bioaccumulative

Sources of key data used tocompile the Material Safety
Data Sheet:Internal technical data, data from raw material SDSs, OECD
eChem Portal search results and European Chemicals Agency, http://echa.europa.eu/

Revision Date:

09/30/2023

The information provided in this Safety Data Sheet is correct to the best of our knowledge,
information and belief at the date of its publication. The information is designed only as a
guidance for safe handling, use, processing, storage, transportation, disposal and release andshall not be considered a warranty or quality specification of any type. The information provided
relates only to the specific material identified at the top of this SDS and may not be valid when the
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SAFETY DATA SHEET
according to the OSHA Hazard Communication Standard

Mianserin Formulation
Version
3.8

Revision Date:
09/30/2023

SDS Number:
1601083-00012

Date of last issue: 04/04/2023
Date of first issue: 05/01/2017

SDS material is used in combination with any other materials or in any process, unless specified
in the text. Material users should review the information and recommendations in the specificcontext of their intended manner of handling, use, processing and storage, including anassessment of the appropriateness of the SDS material in the user’s end product, if applicable.
US / Z8

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