Trimer Structure S Protein Veriﬁed by SEC-MALS
ACROBiosystems has developed the S protein with a trimeric structure. The molecular weight and polymer
form of the protein were veriﬁed by SEC-MALS technology, and the bioactivity was veriﬁed by SPR and ELISA.

SARS-CoV-2 Inhibitor Screening Kit
ACROBiosystems has developed the SARS-CoV-2 inhibitor screening kit based on the biotinylated ACE2protein and SARS-CoV-2 S protein RBD. This inhibitor screening kit is designed to facilitate the identiﬁcationand characterization of SARS-CoV-2 inhibitors.

Biotinylated SARS-CoV-2 proteins
We also oﬀer high quality biotinylated S1, S RBD, N, ACE2 and other proteins using the AvitagTM technology.

The biotinylation only happens on the lysine residue of Avi tag, and no interference with the target protein's
natural binding activities.

Besides the high-quality proteins and kit, ACRO also oﬀers the following beneﬁts

SPR/ BLI/ ELISA protocols are oﬀered for free.

Buy a large size of ACE2, S, S1 proteins and get a small size one for free.

ACROBiosystems+1 800-810-0816(US / Canada) +86 400-682-2521(Asia & Paciﬁc) techsupport@acrobiosystems.com 1 Innovation Way, Newark, DE 19711

Cat. No.: SPN-C52H8 Product: SARS-CoV-2 (COVID-19) S protein, His Tag, Active Trimer

Purity of SARS-CoV-2 (COVID-19) S protein is higher than 85%, andthe molecular weight is 640-680 kDa as veriﬁed by SEC-MALS.

The aﬃnity constant of human ACE2 protein binding to SARS-CoV-2(COVID-19) S protein trimer protein was 35.3 nM as veriﬁed by SPR.

Human ACE2, Fc Tag (Cat. No. AC2-H5257) Captured on CM5 chip via anti-human IgG Fcantibodies surface can bind SARS-CoV-2 S protein (R683A, R685A), His Tag, active trimer(Cat. No. SPN-C52H8) with an aﬃnity constant of 35.3 nM as determined in a SPR assay(Biacore 8K).

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Request for FREE protocol

Cat. No.: EP-105 Product: SARS-CoV-2 Inhibitor Screening Kit

Binding of biotinylated human ACE2 to immobilized SARS-CoV-2 S

Inhibition of biotinylated human ACE2 :SARS-CoV-2 S protein RBD

Immobilized SARS-CoV-2 S protein RBD at0.5 μg/mL (100 μL/well) can bind human
ACE2-Biotin with a linear range of 0.0010.06 μg/mL when detected by StreptavidinHRP. Background was subtracted
from data points before curve ﬁtting.

1:2 serial dilutions of SARS-CoV-2 inhibitor (Cat.
No. AC2-H5257), from 20 μg/mL to 0.039μg/mL(180 nM to 0.35 nM) was added into
biotinylated ACE2: SARS-CoV-2 S protein RBD
binding reactions. The assay was performed
according to the protocol. Background wassubtracted from data points prior to logtransformation and curve ﬁtting.

protein RBD in a functional ELISA assay.

binding by SARS-CoV-2 inhibitor

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Product List

*Click the Cat. No. below for more product information

More related products and ELISA kits are coming soon. Please visit www.acrobiosystems.com for the latest and most complete
product information.

Molecule

Click HereCat. No.

Species

Host

Human

HEK293

Human

HEK293

S protein RBD

EP-105

SARS-CoV-2

ACE2

AC2-H82F9

Human

ACE2

AC2-H82E6

ACE2

AC2-H5257

S protein
S protein

SPN-C52H4
SPN-C52H8S1 protein

S1N-C52H3

S1 protein
S1 protein

S1N-C82E8
S1N-S52H5

S protein RBD

SPD-C82E9

S1 protein

S1N-C52H4

S protein RBD

SPD-C5255

Nucleocapsid protein
Nucleocapsid protein

NUN-C51H9

S protein RBDACROBiosystems

SPD-S52H6

NUN-C5227

SARS-CoV-2
SARS-CoV-2
SARS-CoV-2
SARS-CoV-2
SARS

SARS-CoV-2
SARS-CoV-2
SARS-CoV-2
SARS

SARS-CoV-2
SARS-CoV-2

HEK293

HEK293
HEK293
HEK293
HEK293
HEK293
HEK293
HEK293
HEK293
HEK293E.coli

HEK293

Product Description

SARS-CoV-2 Inhibitor screening Kit

Biotinylated Human ACE2 / ACEH Protein, His, Avitag™ (MALS veriﬁed)
Biotinylated Human ACE2 / ACEH Protein, Fc, Avitag™
Human ACE2 / ACEH Protein, Fc Tag (MALS veriﬁed)

SARS-CoV-2 (COVID-19) S protein (R683A, R685A), His Tag
SARS-CoV-2 (COVID-19) S protein (R683A, R685A), His Tag, active trimer (MALS veriﬁed)
SARS-CoV-2 (COVID-19) S1 protein, His Tag

Biotinylated SARS-CoV-2 (COVID-19) S1 protein, His, Avitag™ (MALS veriﬁed)
SARS S1 protein, His Tag (MALS veriﬁed)

SARS-CoV-2 (COVID-19) S1 protein, His Tag (MALS veriﬁed)

Biotinylated SARS-CoV-2 (COVID-19) S protein RBD, His, Avitag™ (MALS veriﬁed)
SARS-CoV-2 (COVID-19) S protein RBD, Fc Tag (MALS veriﬁed)
SARS S protein RBD, His Tag (MALS veriﬁed)

SARS-CoV-2 (COVID-19) Nucleocapsid protein, His Tag
SARS-CoV-2 (COVID-19) Nucleocapsid protein, His Tag+1 800-810-0816(US / Canada) +86 400-682-2521(Asia & Paciﬁc) techsupport@acrobiosystems.com 1 Innovation Way, Newark, DE 19711