MATERIAL SAFETY DATA SHEETMSDS No. 6010-0001
Revised Date June 21, 2022
1/7 page
1. PRODUCT AND COMPANY IDENTIFICATIONPRODUCT NAME
： CO2 Trap Cartridge, replacement cartridges for removing carbon dioxide andmoisture protection.
NAME OF SUPPLIER： GL Sciences Inc.
ADDRESS： 22-1 Nishishinjuku 6-chome Shinjuku-ku Tokyo 163-1130, JapanCHARGE SECTION： International Sales Section
TELEPHONE No.
： +81-3-5323-6620
FACSIMILE No.
： +81-3-5323-6621
PRODUCT No.
： 6010-92050, 6010-92060, 5010-29902、5010-、6010MSDS No.
： 6010-0001
Research use only.
2. HAZARDS IDENTIFICATIONThis product consists of a CO2 trap cartridge and a dedicated solvent bottle and parts.
The solvent bottle and parts, luer stop valve, and plug are molded products and are not classified as hazard
ous.The three cartridges are filled with silica gel for moisture removal, Ascarite II for CO2 removal, and Active alumina for moisture absorption protection, and are used for testing and research, especially in the fieldof chromatography.
《CO2 absorbing cartridge [ Silica gel]》
GHS CLACCIFICATION：Not classificable
HAZARDS SYMBOL：- - SIGNAL WORD：- - HAZARD STATEMENTS：- - PRECAUTIONARY STATEMENTS ：- - OTHER INFORMATIONS：May be harmful if inhaled and ingested.
May cause eye and skin irritation.
Dispose of contents/container in accordance with all applicable regulations.
MOST IMPORTANT HAZARDS：Eye irritation, skin irritation, digestive tract irritation, respiratory tract irritation.
《CO2 absorbing cartridge [ Ascarite Ⅱ]》
GHS CLASSIFICATION：Skin corrosion/irritation: Category 1
Serious eye damage/eye irritation: Category 1
Specific target organ toxicity - single exposure: Category 1<respiratory system>
Acute aquatic toxicity: Category 3
HAZARD SYMBOL：SIGNAL WORD
：Danger
HAZARD STATEMENTS：
H314
Causes severe skin burns and eye damage.
H318
Causes serious eye damage.
H370
Causes damage to respiratory system.
H402
Harmful to aquatic life.
PRECAUTIONARY STATEMENTS ：P260
Do not breathe dust/fume/gas/mist/vapours/spray.
P264
Wash hands thoroughly after handling.
P270
Do not eat, drink or smoke when using this product.
P273
Avoid release to the environment.
P280
Wear protective gloves/protective clothing/eye protection/face protection.
P301+P330+P331
IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303+P361+P353
IN ON SKIN or hair: Remove/Take off immediately all contaminated clothing.
Rinse skin with water/shower.
P304+P340
IN INHALED: Remove victim to fresh air and keep at rest in a position
comfortable for breathing.
P305+P351+P338
IF IN EYES: Rinse cautiously with water for several minutes.
Remove contact lenses, if present and easy to do. Continue rinsing.
P307+P311
IF exposed: Call a POISON CENTER or doctor/physician.
P363
Wash contaminated clothing before use.
P405
Store locked up.
P501
Dispose of contents/ container to an approved waste disposal plant.

PRODUCT NAME ： CO2 Trap Cartridge, cartridge for removing carbon dioxide and moisture protection.
MSDS No.6010-0001
Revised Date June 21, 2022
2/7 page《Moisture protection cartridge [ Active alumina]》
GHS CLASSIFICATION： Specific target organ toxicity (Single exposure)： Category 3(respiratory irritation)
Specific target organ toxicity (Repeated exposure)： Category 1(lungs)
HAZARD SYMBOL：SIGNAL WORD
： Danger
HAZARD STATEMENTS：
H335
May cause respiratory irritation
H372
Cause damage to organs through prolonged or repeated exposure
PRECAUTIONARY STATEMENTS ：P260
Do not breathing dust.
P271
Use only outdoors or in a well-ventilated area.
P264
Wash hands thoroughly after handling.
P270
Do not eat, drink or smoke when using this product.
P304+P340
IF INHALED: Remove person to fresh air and keep comfortable for breat
hing.
P314
Get medical attention if you feel unwell.
P403+P233
Store in a well-ventilated place. Keep container tightly closed.
P405
Store locked up.
P501
Dispose of contents/container in accordance with all applicable regulations.
3. COMPOSITION/INFORMATION ON INGREDIENTS[ Silica gel]
CHEMICALNAMECONTENTSYNONYMSCHEMICALFORMULACAS No.

TSCA
INVENTRY

EINECS No.

Silica gel

--

--

SiO 2

7631-86-9

Listed231-545-4

CONTENTSYNONYMS

CAS No.

TSCA
INVENTRY

EINECS No.

90-95%

Caustic
soda

CHEMICALFORMULA
NaOH

1310-73-2

Listed215-185-55-10%ZololiteⓇ(Mg,Fe)3 (Si,Al,Fe)4 O10(OH) 2･4H2 O

1318-00-9

Not
ListedNot
ListedCONTENTSYNONYMS

CAS No.

TSCA
INVENTRY

EINECS No.

--

Alumina,α-alumina

CHEMICALFORMULAAl 2 O31344-28-1

Listed215-691-6[ Ascarite Ⅱ]
CHEMICAL
NAME
Sodiumhydroxide
Vermiculite[ Active alumina]
CHEMICAL
NAME
Aluminiumoxide

4. FIRST AID MEASURES
GENERAL ADVICEINHALATIONSKIN CONTACT： If fragments/respirable dust contacts with eyes or skin, wash off immediately
with soap and plenty of water. In the case of respirable dust and/or fumes, use
self-contained breathing apparatus and dust impervious protective suit. Use
personal protective equipment. If irritation persists, consult a physician.
： Move victim to fresh air and gargle. If breathing is difficult, give oxygen.
If irritation persists, consult a physician.
： Remove contaminated clothes and shoes, rinse skin with plenty of water orshower. Use soap to help assure removal. If irritation persists, consult aphysician.

PRODUCT NAME ： CO2 Trap Cartridge, cartridge for removing carbon dioxide and moisture protection.
MSDS No.6010-0001
EYE CONTACT

Revised Date June 21, 2022
3/7 page： Remove any contact lenses at once. Flush eyes well with flooding large amountsof running water for at least 15 minutes. Assure adequate flushing by separating
the eyelids with sterile fingers. If irritation persists, consult a physician.
INGESTION： Rinse mouth, give plenty of water to vomit. Never give anything by mouth to an
unconscious person. Consult a physician.
MOST IMPORTANT SYMPTOMS AND EFFECTS： Shreds and dusts may cause irritation of mucous membranes, respiratory tract,skin and eyes.

5. FIRE FIGHTING MEASURES
EXTINGUISHING MEDIA： This product is noncombustible.
FIRE & EXPLOSION HAZARDS： Toxic and irritating dust, fumes or smoke may be emitted.
SPECIAL PROTECTIVE EQUIPMENT FOR FIRE FIGHTERS： Fireman should wear normal protective equipment (full bunker gear) andpositive-pressure self-contained breathing apparatus.
6. ACCIDENTAL RELEASE MEASURESPERSONAL PRECAUTIONS： Remove ignition sources and ventilate the area.
In case of insufficient ventilation, wear suitable respiratory equipment.
Avoid raising dust and avoid contact with skin and eyes.
ENVIRONMENTAL PRECAUTIONS： Prevent spills from entering sewers, watercourses or low areas.
METHODS FOR CLEANING UP： Do not touch spilled material without suitable protection. After material iscompletely picked up, wash the spill site with soap and water and ventilate thearea. Pull all wastes in a plastic bag for disposal and seal it tightly. Remove,clean, or dispose contaminated clothing.
7. HANDLING AND STORAGE
HANDLING

STORAGEINCOMPATIBLE PRODUCTS： Avoid contact with eyes, skin, and clothing. Avoid prolonged or repeatedexposure. Handle material with suitable protection.
After using this product, dispose of contents/container in accordance with allapplicable regulations and appropriate ways.
： Store away from moisture and water in well-ventilated dry place.
Keep container tightly closed.
： Water, moisture、strong oxidizers, acids.

8. EXPOSURE CONTROL/PERSONAL PROTECTION
ENGINEERING MEASURES： Use exhaust ventilation to keep airborne concentrations below exposure limits.
Use adequate ventilation.
VENTILATION： Local Exhaust ; Necessary, Mechanical(General) ; Recommended
PERSONAL PROTECTION
Respiratory protection
HAND PROTECTION
EYE PROTECTION
SKIN PROTECTIONCONTROL PARAMETERSCHEMICAL NAME
Silica gel
Sodium hydroxide
Vermiculite
Aluminium oxide： Use respirators approved under appropriate government standards and follow
all regulations.
： Chemical resistant gloves： Safety glasses(goggles)： Protective clothing
OSHA PEL-CL 2mg/m3 (air)Not available
TWA 15mg/m3 (total)
TWA 5 mg/m3 (resp.)

NIOSH REL
-C 2mg/m3
Not available

ACGIH
3mg/m 3
CL 2mg/m3
Not available

Not available

TWA 10mg/m3 (total)

9. PHYSICAL AND CHEMICAL PROPERTIESPHYSICAL STATE： PowderCOLOUR： slightly light yellow to light brown ; Ascarite Ⅱ.
slightly light white-gray to white ; Active almina.
ODOR： Odorless
MELTING POINT / FREEZING POINT： No data available

PRODUCT NAME ： CO2 Trap Cartridge, cartridge for removing carbon dioxide and moisture protection.
MSDS No.6010-0001
Revised Date June
BOILING POINT OR INITIAL BOILING POINT AND BOILING RANGE： No data available
FLAMMABILITY： No data available
LOWER AND UPPER EXPLOSION LIMIT / FLAMMABILITY LIMIT： No data available
FLASH POINT： No data available
AUTO-IGNITION TEMPERATURE ： No data available
DECOMPOSITION TEMPERATURE： No data available
pH： No data available
KINEMATIC VISCOSITY： Not applicable
SOLUBILITY
Water： insoluble
Organic solvent： insoluble
PARTITION COEFFICIENT
n-octanol/water (log value)： No data available
VAPOUR PRESSURE： No data available
DENSITY AND/OR RELATIVE DENSITY： No data available
RELATIVE VAPOUR DENSITY： No data available
PARTICLE CHARACTERISTICS ： Not applicable21, 2022

4/7 page

10. STABILITY AND REACTIVITY
REACTIVITYCHEMICAL STABILITY
CONDITION TO AVOID： Stable under recommended storage conditions.
： Reacts with strong oxidizers.
： Sunlight, heat, open flames, high temperature, sparks, static electrical charge,other ignition sources, moisture
INCOMPATIBLE MATERIALS： Oxidizers and strong acids
HAZARDOUS DECOMPOSITION PRODUCTS： CO, CO 2. Nitrogen oxides, cyanides

11. TOXICOLOGICAL INFORMATIONACUTE TOXICITY (Oral)： No data available.
ACUTE TOXICITY (Dermal)： No data available.
ACUTE TOXICITY (Inhalation: Vapors)： No data available.

ACUTE TOXICITY (Inhalation: Dusts and mists)： No data available.

SKIN CORROSION/IRRITATION(Sodium hydroxide)：： In a study in which 2N (8%), 4N (16%), and 6N (24%) solutions were applied to the abdomen of pigs, large blisters appeared within 15 minutes,
the 8% and 16% solutions caused severe necrosis in all epidermal layers, and the 24% solution caused numerous and severe blisters with necr
osis deep into the subcutaneous tissue (SIDS (2009)). (SIDS (2009)), an
d severe necrosis was reported when a 5% aqueous solution was applie
d to rabbit skin for 4 hours (ACGIH (7th, 2001)). The pH is 12 (0.05%w/w) (Merck (14th, 2006)). It is classified as C and R35 in the EU classi
fication.
EYE DAMAGE/EYE IRRITATION ：(Silica gel)
： In an eye irritation test (OECD TG 405) using rabbits, it was reported that application of precipitated silica (CAS No.: 112926-00-8) did not cause
irritation (SIDS (2006), ECETOC JACC (2006)). There are several reportsof studies in which precipitated silica or amorphous silica (CAS No.: 112945-52-5) in different forms were applied to rabbits and no eye irritation
was reported, as well as reports of mild conjunctivitis, mild to moderate
conjunctival redness, and corneal opacity, but all symptoms were reporte
d to be recoverable. However, all symptoms were reported to be recoverable (SIDS (2006), ECETOC JACC (2006)).

PRODUCT NAME ： CO2 Trap Cartridge, cartridge for removing carbon dioxide and moisture protection.
MSDS No.6010-0001(Sodium hydroxide)

Revised Date June 21, 2022
5/7 page： A 1.2% solution or a concentration of 2% or higher is described as corr
osive to rabbit eyes (SIDS (2009)), and the pH is 12 (0.05% w/w) (Merc
k (14th, 2006)). There have been numerous reports of human accidents i
nvolving severe eye damage due to high concentrations of dust or solution (ACGIH (7th, 2001)) and accidental eye contact resulting in blindness(DFGOT vol. 12 (1999)). It is also corrosive to skin and is classified as
C and R35 in the EU classification.
RESPIRATORY OR SKIN SENSITIZATION： No data available.
SKIN SENSITIZATION：(Sodium hydroxide)： In a skin sensitization study by male volunteers, a 0.063% - 1.0% solution wasapplied to the back for induction, and 7 days later a 0.125% solution was
reapplied. There was a dose-dependent enhancement of irritation, but noenhancement of reaction on the reapplied patch surface. Thus, sodiumhydroxide was not a skin sensitizer. Furthermore, sodium hydroxide has been
widely used for many years, and there have been no reported cases of skinsensitization in humans, leading to the conclusion that sodium hydroxide is notconsidered a skin sensitizer (SIDS (2009)).
GERM CELL MUTAGENICITY：(silica gel)
： In vivo, negative in a dominant lethal test in rats by oral administration
and a chromosomal aberration test in rat bone marrow cells by oral adm
inistration (ECETOC JACC (2006), SIDS (2006)); in vitro, negative in a bacterial reverse mutation test, a gene mutation test in mammalian culture
d cells, and a chromosomal aberration test in mammalian cultured cells(ECETOC JACC (2006), SIDS (2006)). In vitro, it is negative in bacterial
reverse mutation test, gene mutation test, and chromosomal aberration test, and weakly positive in micronucleus test of cultured mammalian cells(ECETOC JACC (2006), SIDS (2006)).
(sodium hydroxide)： As in vivo data, no significant increase in micronuclei was observed in the
micronucleus test using bone marrow cells administered intraperitoneally to
mice (somatic cell in vivo mutagenicity test) (SIDS (2009)) and in thechromosome aneuploidy induction test using oocytes administeredintraperitoneally to mice ( In a germ cell in vivo mutagenicity study using oocytes
injected intraperitoneally into mice (SIDS(2009)), no evidence of chromosome
disjunction was found (SIDS(2009)). As for in vitro mutagenicity testing,negative results in the Ames test (SIDS(2009)) and false positive results in thechromosome aberration test using CHO K1 cells (SIDS(2009)) have beenreported.
CARCINOGENICITY：(silica gel)
： The substance group indicated by this CAS number is silica (SiO2) and i
ncludes all forms of silica (ECETOC JACC No. 51 (2006)). This substance group includes crystalline silica and its carcinogenicity classification res
ult is considered applicable.
(sodium hydroxide)： Negative in a 12-week oral carcinogenicity study in rats (DFGOT vol. 12 (1999)).
REPRODUCTIVE TOXICITY： No data available.
SPECIFIC TARGET ORGAN TOXICITY-Single exposure：(Silica gel)： Silica gel (CAS No.: 112926-00-8) is reported to be an airway irritant (SIDS (2006), ECETOC JACC (2006)).
(sodium hydroxide)： Acute inhalation exposure to dust or mist may cause irritation of mucous
membranes, followed by coughing and dyspnea, and if exposure is more
severe, pulmonary edema and shock may result (PATTY (5th, 2001)). So
me authors also state that dust formation is unlikely due to physicochemi
cal properties such as deliquescence and minimal vapor pressure (SIDS(2009)). Other reports include 28 cases of accidental ingestion in which
50-200 mL of an estimated 25-37% solution caused injuries to the uppergastrointestinal tract and esophagus (SIDS (2009)), and numerous reportsof serious (accidental ingestion) accidents and suicides causing severe
corrosion from the oral cavity to the esophagus (DFGOT vol. 12 ( 1999).
(Aluminum oxide)： Upper respiratory tract irritation (ICSC (2000)).

PRODUCT NAME ： CO2 Trap Cartridge, cartridge for removing carbon dioxide and moisture protection.
MSDS No.6010-0001
Revised Date June 21, 2022
6/7 page
SPECIFIC TARGET ORGAN TOXICITY-Repeated exposure：(Silica gel)
： In humans, silicosis has been reported with quartz and cristobalite. In ad
dition, fibrogenicity has been reported in experimental animals with quartz
and cristobalite. In addition, autoimmune disease, chronic renal disease
and asymptomatic renal degeneration have been reported with quartz, and regression fever such as metal fume fever with fused silica (ACGIH (7th, 2006)).
(Sodium hydroxide)： Described as having no animal study data on repeated exposure by oral,
dermal, inhalation or other routes (SIDS (2009)), and little data on effec
ts on humans, so cannot classify due to lack of data. In addition, there is a description (ACGIH(7th, 2001)) that repeated aerosol inhalation expos
ure in rats caused lung damage, but the exposure concentration is unkn
own. It is stated that dust formation is unlikely due to physicochemical properties such as deliquescence and minimal vapor pressure (SIDS(2009)).
(Aluminum oxide)： Occupational exposure to aluminum oxide has been reported to cause
adenopathy in the lungs (EHC(1997)).
ASPIRATION TOXICITY： No data available.
12. ECOLOGICAL INFORMATIONECOTOXICITY： No data available
BIODEGRADABILITY： No data available
BIOACCUMULATIVE POTENTIAL ： No data available
MOBILITY IN SOIL
： No data available
HAZARDOUS TO THE OZONE LAYER： Not listed in Montreal Protocol list.
13. DISPOSAL INFORMATION
Dispose in a hazardous-waste site in accordance with all applicable regulations. Any disposal practice must be incompliance with country, local, state, and federal laws and regulations (contact country, local or state environment
agency for specific rules).
14. TRANSPORT INFORMATIONInternational Regulations
Maritime regulations： Conform to the provisions of IMO.
UN No.
： 1823
Proper Shipping Name ： SODIUM HYDROXIDE, SOLID
Class：8Packing Group： II
Marine Pollutant： Not applicable
Aviation regulations： Conform to the provisions of ICAO/IATA.
UN No.
：1823
Proper Shipping Name
： Sodium Hydroxide, Solid
Class：8
Packing Group： II
Emergency Response Guideline No.
：154
15. REGULATORY INFORMATIONFor classification and labeling of chemicals in accordance with the applicable rules and regulations in the EU or eachcountry, refer to GHS classification of this product (See Section 2).
US REGULATION
EU REGULATION： OSHA HCS 2012/29 CFR 1910.1200： CLP Regulation ((EC) No. 1272/2008)

PRODUCT NAME ： CO2 Trap Cartridge, cartridge for removing carbon dioxide and moisture protection.
MSDS No.6010-0001
Revised Date June 21, 2022
7/7 page
16. OTHER INFORMATIONNOTICE:The information contained in the SDS description is applicable exclusively to the chemical substance identified herein
and for its intended use as an analytical reference standard or reagent and to the unit quantity intended for that
purpose. The information does not relate to, and may not be appropriate for, any application or larger quantity of thesubstance described. Our products are intended for the use by individuals possessing sufficient technical skill andqualification on use the material potential hazardous chemical. Accordingly, no representation or warranty, express
or implied, with respect to merchantability and fitness for a particular purpose is made with respect to the information
contained herein.
Attention:
This product in terms of chemical identity and the unit amount provide is intended for use in chemical analysis andnot for human consumption, nor any other purpose.