ASTELLAS US HEADQUARTERS
CORPORATE OVERVIEW

Astellas Pharma US, Inc., is an affiliate of Tokyo-based global pharmaceuticalcompany Astellas Pharma Inc. We pioneer first-in-class health solutions that havetransformed disease management and reshaped patients’ expectation of care.
Astellas is focused on turning innovative science into medical solutions that bringvalue and hope to patients and their families, especially those impacted by serious
diseases with no or limited treatment options.
FY2022 FINANCIAL HIGHLIGHTS (USD) *Accurate as of August 2023
GLOBAL NET SALESASTELLAS US NET SALESR&D INVESTMENT$11.2 BILLION$4.8 BILLION

18% OF SALESREVENUE(1,518,619 million yen)

ASTELLAS MILESTONESIn 2005, following the merger of yamanouchi & Fujisawa, two of Japan’slargest and most respected pharmaceutical companies, Astellas established
its U.S. headquarters near Chicago.

HEADQUARTERS IN THE U.S.
2375 Waterview Drive
Northbrook, IL 60062-6111
EMPLOYEESU.S. | 3,000+
Global | 14,000+
TICKER SYMBOLASTELLAS US MARKETED
PHARMACEUTICAL PRODUCTS
OH

2008
Clinical development
HQ function moved to the U.S.

2012
Astellas opens new
Headquarters for the Americas
in Northbrook, Ill.

2016
Astellas acquires Ocata
Therapeutics, Marlborough, Mass.,and establishes the Astellas Institutefor Regenerative Medicine

Astellas acquires Ogeda SA,Gosselies, Belgium, to expand
its late stage pipeline

Astellas acquires Ganymed
Pharmaceuticals, Mainz, Germany,
to expand its oncology pipeline

2017

2017

Astellas opens new drug
discovery and development hub in
San Diego, Calif, Astellas ResearchInstitute of America (ARIA)

Astellas acquires Mitobridge,Cambridge, Mass., to advanceand expand developments
targeting mitochondrial functions

2018

2018

Astellas acquires Quethera,Cambridge, UK, to further support
Astellas’ research into new ophthalmic
targets, including glaucoma.

Astellas acquires Universal
Cells, Seattle, Wash., to expand
innovative cell therapy treatments

2019
Astellas acquires
Xyphos Biosciences, Inc.,San Francisco, Calif., to strengthen
its immuno-oncology pipeline

2020
2022
Astellas opens large-scale
gene therapy manufacturing
facility in Sanford, N.C.

OSNH

Astellas acquires New York based
OSI to support new focus
on oncology

2017

Astellas acquires Potenza
Therapeutics, Cambridge, Mass.,
to build a portfolio of novel
immuno-oncology (IO) therapies

HN2010

2017

2018

4503

NNH 2

CARDIOLOGYOPHTHALMOLOGYLEXISCAN®
(regadenoson – injection)

IZERVAY™
(avacincaptad pegolintravitreal solution)

INFECTIOUS
DISEASE

TRANSPLANTAMBISOME®
(amphotericin B –lipsome for injection)

ASTAGRAF XL®
(tacrolimus extended-releasecapsules)

CRESEMBA®
(isavuconazonium sulfate –capsules and injection)

PROGRAF®
(tacrolimus – capsules,granules and injection)

ONCOLOGYUROLOGYXTANDI®
(enzalutamide – capsules)

MYRBETRIQ®
(mirabegron –extended-release tablets)

XOSPATA®
(gilteritinib – tablets)
PADCEV®
(enfortumab vedotin-ejfv –intravenous infusion)

VESICARE®
(solifenacinsuccinate – tablets)
WOMEN’S HEALTH
VEOZAH™
(fezolinetant – tablets)

Astellas completes acquisitionof Audentes Therapeutics,
San Francisco, Calif., and creates agenetic regulation primary focus area

2023
Astellas completes acquisition ofIveric Bio, New Jersey, and launches
IZERVAY for geographic atrophy
secondary to age

MEDIA CONTACT | corporate.communications@us.astellas.com | astellas.com/usAstellasUS@AstellasUS@astellas-pharma-us

ASTELLAS OPERATIONS IN THE UNITED STATES
Astellas Pharma US
Headquarters for Astellas USNorthbrook, Illinois

Astellas Gene Therapies
San Francisco Bay Area, California(formerly Audentes)

Astellas Pharma
Global Development
Northbrook, Illinois

Astellas Gene Therapies
Manufacturing Facility
Sanford, NC

Policy and Government Affairs
Washington, D. C.

Astellas Institute for Regenerative Medicine
Westborough, Massachusetts
Universal Cells
Seattle, Washington
Xyphos Biosciences
South San Francisco, California

Astellas Venture Management
South San Francisco, California;
Cambridge, Massachusetts
Astellas Innovation Management
South San Francisco, California
Mitobridge and New Life Sciences
Facility (Opening 2024)
Cambridge, Massachusetts
iota Biosciences
Alameda, California

ASTELLAS US LEADERSHIP
Mark Reisenauer
President, Astellas US
Lynn Fenicchia
Senior Vice President,
Head of US Medical
Specialties Business Unit
Christie Bloomquist
Vice President,
Government Affairs
and Policy

Phil Tennant
Senior Vice President,
Head of US Oncology
Business Unit
Lei Ding
Senior Vice President,
Market Access andCommercial Capabilities

MEDIA CONTACT | corporate.communications@us.astellas.com | astellas.com/us

Astellas US has beenrecognized by: Seramount’s
100 Best Companies for
Working Parents; Fortune’s
Best Workplaces in Chicago;
BioSpace’s Best Places to Workin Biopharma; and the Human
Rights Campaign Foundation’s
Corporate Equality Index.

Astellas has seven dynamic
employee impact groups (EIGs)
focused on empowering
employees to establish diverseand inclusive support
communities within theorganization. These EIGs
include: African American;
Asian; Hispanic; LGBTQ+;
Military; Abilities andStellar Women.

AstellasUS@AstellasUS@astellas-pharma-us

BENEFITS
STELLAR REWARDS

Astellas’ commitment to changing tomorrow includes operating in asocially responsible way every day, and making Astellas an elite place towork in the United States. We are constantly reviewing our total rewards
package to ensure our employees receive valuable and highly
competitive beneﬁts and reward opportunities.

GIVING BACK
Employees have volunteered more thanPAY FOR PERFORMANCE
Competitive Pay
Performance-Driven Meritand Promotional Increases
Performance Bonuses
Long-Term Incentives

FINANCIAL BENEFITS
401(k) Savings with Company
Match and Annual Contribution
Annual Financial Wellness Allowance
Tuition Reimbursement
Adoption AssistancePAID TIME OFF
Vacation, Holidays & Sick Time
Annual Company Summerand Winter Breaks
Volunteer Time Off
Parental School Time Off
Heritage Days

HEALTH BENEFITS
Medical/Prescription
Retiree Medical
DentalVision
Telemedicine Services
Voluntary Second Opinion Program
Flexible Spending AccountWellbeats Membership

PAID LEAVES
Maternity/Paternity Leave
Bridge Back to Work Program
After Maternity/Paternity
Disability Leave
Family Care Leave
Military Leave
FLEXIBLE WORK OPTIONS
Flexible Work Schedule
Telecommuting
FAMILY CARE SOLUTIONS
Adult & Parental Care
Child & Kid Care
Identity Theft Protection
Kindergarten-College
Tutoring Services
Veterans SupportPeople Living with Disabilities
Mental/Behavioral Health Support
Employee Assistance Program

AND MORE
Employee Referral Bonus Program
Relocation Programs
Matching Gifts Program
Executive Benefit Programs(for eligible positions)
Voluntary Legal Services
Carrot Fertility
Short-Term/Long-Term Disability
Health and Financial
Wellness Program
Company Paid Life Insurance
Voluntary Life and Dependent
Life Insurance

MEDIA CONTACT | corporate.communications@us.astellas.com | astellas.com/us

198,059 HOURS
GLOBALLY SINCE 2009

Employees and Astellas
have donated more than

$1.5 MILLION
THROUGH THE COMPANY’S MATCHING
GIFTS PROGRAM

Our commitment to changing tomorrow ismeasured not only by our focus on bringing
innovative and effective new medicines
to patients and physicians, but also by theimportance we place on the impact we makewithin the communities where wework and live.
Our employees participate and haveaccess to the following programs as partof our efforts:
Changing Tomorrow Day: Throughout theyear and around the world, our annual Astellas
Changing Tomorrow Day events mobilize
employees to commit to an entire day ofservice to local nonproﬁt organizations focusedon key areas of need.
Volunteer Time Off Program: Astellasprovides up to five days paid time off to full-time
employees to volunteer for charitableorganizations. The Volunteer Time off Leave
is in addition to holiday or vacation time.
Matching Gifts Program: Astellas will match,dollar for dollar, employee contributions madeto four organizations: American Cancer Society,
American Red Cross, Habitat for Humanity andStarlight Children’s Foundation.

AstellasUS@AstellasUS@astellas-pharma-us