Pipette Management
Solutions by A&D
For quick checking of pipette airtightness…

Leak Tester: AD-1690

To protect research results fromthe threat of nonconformities

For verification of pipette accuracy and precision…

Pipette Accuracy Testers:
BM Series + BM-014, etc.

For easy implementation of daily and periodic pipette checks…

Pipette Professional: AD-1695

ISO
9000 CERTIFIED

What If You Were Told to Create a Pipette
Management SOP * Within Three Weeks?
11*1 Standard Operating Procedure

Today, what with GLP and ISO, researchers are in increasing need of sustainableways to verify the quality and performance of their pipettes in-house. The
problem is, however, that many of them would be at a loss as to what exactly
they should put into actual practice. Wouldn’t you be too?
Not to worry, though. A&D provides the following powerful solutions that you
can use to introduce a simple, viable SOP for pipette management.

For Daily Checks

Leak Tester

AD -1690

Pipette failures typically occur due to degraded parts in the lower section of the pipette likethe o-ring, piston, and tip holder compromising the pipette’s airtightness. By depressurizing(to −20 kPa) inside the pipette, the AD-1690 can determine whether an air leak exists in amatter of seconds, allowing you to quickly sort out troubled pipettes.
A&D suggests that for everyday inspection, this leak test along with some quick appearance
and function checkups will suffice for most users.

2

Advantages✔ Takes only seconds to tell whether the pipette has a leak
✔ Changes pressure by evacuating air instead of injecting it*2, so that no dust enters
the pipette being tested✔ Easily replaceable air filter, which protects
the AD-1690 from dust when it intakes air✔ Equipped with an RS-232C interface to output
test results to an external device such as theAD-1695 Pipette Professional (see later pages)✔ Four attachments and one adapter tube
provided to fit various tip sizes and shapes

Air filter unit

*2 A pressurization method is available upon request.

For Periodic Checks

Pipette Accuracy Testers

AD - 4212B-PT

AD-4212A-PT
FX-300i-PT
In addition to the daily check, you are advised to inspect the pipettes’ actual performancefrom time to time. For that purpose, A&D’s pipette accuracy testers are useful. The test
procedure follows the gravimetric method *3 and allows compliance with ISO8655.

*3 Obtains the pipette volume based on the mass of purified water dispensed from the pipette
3Advantages✔ Automatic mass-to-volume conversions and judgments for accuracy and repeatability
using the special “WinCT-Pipette” software✔ Judgments by your preferred criteria – manufacturer specifications, ISO8655, oryour own✔ Outputs the test results in an A4 or letter-size report format for documentation
requirements✔ A liquid thermometer, evaporation trap, and calibration weight with a pair oftweezers included as standard✔ Comes packed neatly in a handy carrying case for use in multiple places *4 *5*4 For the AD-4212B-PT, AD-4212A-PT, and FX-300i-PT only
*5 Not advisable when using the 0.001 mg range of the AD-4212B-PT

Evaporation Trap★
The evaporation trap maintains ahigh humidity inside the device
and thereby minimizes theevaporation of the test liquid thatcauses measurement errors. It is nolonger necessary to increase thehumidity of an entire room.

Angled openingfor easier insertionof a pipette
Water
High humidity(RH85% or higher)★ Patent pending

WinCT-Pipette
Main screen

Test report

WinCT-Pipette automatically determines the Z (conversion) factor based on theentered test liquid (i.e. purified water) temperature and barometric pressure, which isthen used to calculate volumes from the mass values transmitted from the balance.
Information for each pipette (including manufacturer, model, and test conditions
and specifications) can be saved and retrieved for later testing. *6*6 It is recommended that the database be backed up on a regular basis.
4Also available...
Micro Analytical Balances

Pipette Accuracy Testing Kit

BM Series + BM-014

The BM-014 can be used with any
model of the BM series (both 5 mL and30 mL cups are provided). This setup isideal if you also want to use thebalance for purposes other thanpipette accuracy testing as an ordinary
analytical balance.

Recommended Models in Accordance With ISO8655
PipetteNominalVolume✦1(µL)
12
5
1020
50
100
200
500
1000
2000
5000
10000

ISO8655 Requirements (Gravimetric Method)
Maximum Permissible ErrorBalance
AccuracyRepeatability
Readability(Systematic Error)(Random Error)±%
5.04.0
2.5
1.2
1.0
1.0
0.8
0.8
0.8
0.8
0.8
0.80.6%
52
1.5
0.8
0.5
0.4
0.3
0.3
0.3
0.3
0.3
0.3
0.3

±µL
0.05
0.08
0.125
0.12
0.2
0.5
0.8
1.6
4.0
8.0
164060

µL
0.05
0.04
0.075
0.08
0.1
0.2
0.3
0.6
1.5
3.0
6.0
15.0
30.0

Daily inspection, simplified verification

Recommended Models

mg0.001(✦2)

BM-20/22 + BM-014

BM-252 + BM-014

0.01AD-4212B-PTBM-200/300/500+ BM-014
0.1orAD-4212A-PT

1 ✦3FX-300i-PT✦1 The maximum volume selectable for variable volume pipettes✦2 Please select the BM-20/22 + BM-014 if you will mainly use the 0.001 mg range, as it will provide much greater stability.
✦3 The minimum weighing value, 1 mg, approximately corresponds to 1 µL. If a pipette volume is 1000 µL, a test can be performed
with a resolution of 0.1%. If 200 µL, 0.5%.
Note) Make sure that the measurement environment is free from vibration, drafts, rapid temperature/humidity changes, etc.

.............................

MPA Series.............................

............... Single Channel Electronic Pipettes ..............

MPA-10

MPA-20

MPA-200

MPA-1200

MPA-10000

0.3 to 10.0 µL

0.3 to 20.0 µL

3.0 to 200 µL

15 to 1200 µL

0.1 to 10.0 mL

Supposing that some of your pipettes have been found inaccurate by your periodic
check, what should you do? If you use the MPA series, it is easy to correct deviations byyourself. All you have to do is simply input the actual dispensed volume measured by apipette accuracy tester into the pipette.★
★ Patent pending

5............................................................

… Still not comfortable enough with what you should do? Then how about
getting some professional help?

For “Guided” Checks

Pipette Professional

AD -1695

Stop dwelling on how to put the said tasks and tools in order by yourself. Leave everything to
the AD-1695. All you have to do is follow the displayed instructions and touch the screen toenter necessary information, commands, selections, etc., so you can perform daily andperiodic checks in ways already laid out by A&D for you.

Daily check (basic check) function
For daily checks, you are simply asked to determine
whether the condition is “met” or “not met” for eachcheck item. The check items include those which
A&D recommends as the most basic ones to confirm
that the pipette meets proper conditions for use.

To perform an air leak test, you can choose (and areencouraged) to connect and use the AD-1690 Leak
Tester, which the AD-1695 can control and capture
the result from to make the met/not met judgment
promptly and automatically.*7*7 Testing without the AD-1690 also possible(albeit time-consuming and often difficult to judge)

6Periodic check (volume test) function
The AD-1695 enables you to easily test for pipettevolume accuracy and repeatability by connecting it toone of A&D’s balances*8. All the key functions
provided by WinCT-Pipette are also available on theAD-1695, so that you can complete both the basic checkand volume test one after another without using a PC.

*8 Either the pipette accuracy testers or the BM series with
BM-014 are strongly recommended, as they come with anevaporation trap and other useful accessories.

Reporting results
The daily and periodic check results can be
output to a USB flash drive in PDF reportformats. A reference number, location
name, and operator name can be added asnecessary.
It is also possible to output the results
directly to a standard mini printer.*9*9 In simplified formats

Daily check report (PDF)

Periodic check report (PDF)

Pipette registration/selection and spec configuration
Up to 300 pipettes’ information (manufacturer,model, serial number, and maximum volume) withvolume test conditions and specifications can beregistered in the AD-1695, which you can select andreadout when conducting daily and periodic checks.
The registered information of the pipette checked
will be automatically reflected in the output reports.

Glossary and quick manual
You can quickly call up the on-screen explanationsof terms that are relevant or used on the AD-1695.
There is also an on-screen instruction manual
available for each of the daily check, periodic check,and pipette registration/selection operations. It willtell you what to do as you touch the number in therespective section.
With these functions, most of the time you are notrequired to look for or refer to any other resource forunderstanding and operating the AD-1695.
7Specifications
Options & Accessories

AD-1690 (Leak Tester)
Depressurization value
Pressure change tolerance
inside the main unit

AD-1690-01−20 kPa ± 20% (Fixed)(Adapter × 1, attachment × 4,
adapter tube × 1)

+0.2 kPa / 10 seconds+0.1 to +20 kPa (Increment: 0.1 kPa)
Monitoring time: From 1 second(Increment: 0.5 seconds)

Pump operation time

Up to 6 seconds

Power supply

AC adapter

Dimensions

231 (W) × 126 (D) × 78 (H) mm

Net weight

Approx. 570 g

Replacement filter set

AD-1690-02Pressure change tolerance: From
Leak judgment conditions

Replacement tube set(Filter unit × 1, filter element × 10)
AD-1690-015

Carrying case *i

AD-1682

Rechargeable battery unit

AD-1688

Weighing data logger *ii*i For the AD-1690 and its AC adapter with additional
space for the AD-1682*ii Leak test data can also be stored

Pipette Accuracy Testers *iii
ModelsAD-4212B-PT

AD-4212A-PT

FX-300i-PT

Weighing capacity *iv

5.1 g / 31 g / 110 g *v

110 g

320 g

Minimum weighing value

0.001 mg / 0.01 mg / 0.1 mg

0.1 mg

1 mgLinearity±0.05 mg / ±0.05 mg / ±0.2 mg±0.3 mg±2 mg

Repeatability (standard deviation) 0.015 mg / 0.05 mg / 0.1 mg

0.15 mg

1 mgDimensions

Weighing unit: 80 (W) × 230 (D) × 200 (H) mm

193 (W) × 262.5 (D)Display (with a stand): 237 (W) × 150 (D) × 155 (H) mm

× 190 (H) mm• Instruction manual • Balance including the weighing pan unit, breeze break, ACadapter and AC adapter ID label • Calibration weight with a pair of tweezers• Evaporation trap • Sample cup with holder (30 mL × 2 / 5 mL × 2) • Liquid thermometer• USB communications kit (USB converter, RS-232C cable, Instruction manual)• WinCT-Pipette (CD-ROM)• Carrying case with a shoulder belt and key

Standard accessories *v

Power consumption

Approx. 11VA (supplied to the AC adapter)

Carrying case dimensions

470 (W) × 150 (D) × 355 (H) mm

Weight (with all accessories in a case)Approx. 7.6 kg

Approx. 6.4 kg

Approx. 7.2 kg*iii Please refer to the dedicated brochure for the specifications of the BM series of micro analytical balances.
*iv When the balance weighing pan is used*v The AD-4212B-PT is equipped with a smart range function. The minimum weighing value will switch to 0.01 mg or 0.1 mg automaticallywhen the mass value exceeds 5.1 g or 31 g respectively but can be reset to 0.001 mg by pressing the RE-ZERO (tare) key.
Options & Accessories AD-1683

Static eliminator
AD-1684A Electrostatic field meter

AD-1687 Weighing environment logger

AD-1695 (Pipette Professional)
Display

TFT color LCD with backlight (7 inches, 800 × 480 dots)

LCD backlight brightness

Adjustable to 10 levels *viData transmission

RS-232C × 3, USB (1.1) × 2 *vii

Operating environment

5 to 40°C (41 to 104°F), 85% RH or less (no condensation)

Power consumption

Approx. 30 VA (supplied to the AC adapter)

External dimensions

203 (W) × 153 (D) × 58 (H) mm, excluding protrusions

Net weight

Approx. 1.1 kg

Standard accessories

Instruction manual, Touch pen with holder, AC adapter, three balance connection cables(D-Sub 9-9, D-Sub 9-25, D-Sub 9-DIN 7), Stand attachment*vi Set to the maximum brightness by default *vii For inserting USB flash drives (the two slots cannot be used at the same time)...Clearly a Better Value
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