Invitation

Overview

3rd Asian Congress for Alterative to Animal Experiments·Date｜ Dec. 14 (Wed) ~ 16(Fri), 2022·Venue｜ ICC Jeju, Korea·Organizer ｜ Korean Society for Alternative toAnimal Experiments (KSAAE)·Sponsor ｜KoCVAM, LUSH, AMOREPACIFIC,
Biosolution

Organized by Korean Society for
Alternatives to Animal Experiments.
The Asian Congress For Alternatives to Animal
Experiments (ACAAE) 2022 is being organized by theKorea Society for Alternatives to Animal Experiments(KSAAE) with the cooperation of the Ministry of Foodand Drug Safety (MFDS). The Organizing Committee is
expecting registering participants from China, India,Japan, and Korea. The Asian Congress is scheduled
to be held from 14th to 16th December, 2022, at ICC
Jeju, Korea.
The Asian Congress will be the 3rd conference ofits kind for researchers from Asia and will afford anopportunity for promoting alternative methods toresearchers in these places, where the concept of theThree Rs is just now achieving penetration. The AsianCongress is intended to achieve multiple missions,which will include disseminating information not juston the latest advances in including pure sciences buton practical applications of the Three Rs worldwide.

Important Deadlines- Registration·Early Bird ｜ Jun.01(Wed) ~ Sep.16(Fri)·Standard ｜ Sep.16(Fri) ~ Nov.01(Tue)- Abstract Submission·Abstract/Poster submission｜~ Nov.01(Tue)THE 19th
ANNUAL MEETING OF
KSAAE

3rd ASIAN CONGRESSALTERNATIVES TO ANIMAL
EXPERIMENTS :FROM ASIA TO THE WORLD2022
12.14.-12.16.
ICC JEJU

Registration Fee
Registraton

StudentGeneral

Early Bird

KRW170,000

KRW370,000

Standard

KRW200,000

KRW400,000

Banquet

KRW30,000

2022
Chair｜Kim, Kwang-Mahn
President of KSAAE, Yonsei UniversityKorean Society for Alternatives to Animal Experiments (KSAAE)
Yonsei Univ. College of Dentistry, 50-1, Yonsei-ro, Seodaemun-gu,Seoul, Republic of Korea
Tel. +82-2-2227-8243
Fax. +82-2-364-9961
Email. ACAAE2022@gmail.com Website. acaae2022.org

Organized bySponsor

Hosted by1st Day (12/14)
Time

2nd Day (12/15)

Halla Hall

Samda Hall

13:0013:20

Opening ceremony    (Room : Halla Hall)

13:2014:10

PL 1
3D reconstructed tissue models in toxicology:
from initial ideal to regulatory acceptanceDr. Helena Kandarova (ESTIV President)

14:1014:20Coffee BreakTime
09:3010:20
10:2010:40
10:4012:20

14:2016:00

S13Rs

S2
Novel in Vitro test:
Development and Application

10:4011:05

14:2014:45

A unique method to formspheroids with various designs
Prof. Nobuhiko Kojima(Yokohama City Univ.)

Using in Vitro and Machine
Learning Approaches to Determine
Dioxin-like Potencies Among Birds
for Brominated Dioxin Analogues
Prof. Rui Zhang (Univ. of Jinan, China)

11:0511:30

14:4515:10

Human iPS Cell-Derived
Cardiomyocytes-Based Cardiac
Safety Assessment of Drugs
Dr. Kentaro Ishida (Myoridge Co. Ltd)

Potential threats of nanoplastic
accumulation in human induced
pluripotent stem cells
Prof. Ju Hyun Park
(Kangwon National Univ. , Korea)

15:1015:35

15:3516:00
16:0016:30
16:3018:00

A 3Rs approach to investigate thebarrier models: a 3D perfusion
tubular Organ on a chip model
Dr. Lisa Franziska Drew (MIMETASinc. from the Netherland)

Development of novel in vitro
methods using human iPS celltechnology
Dr. Yasunari Kanda (National Instituteof Health Science, Japan)

The Fantastic 4: Simcyp Rat,Mouse, Dog, and Monkey
Simulators
Dr. Devendra Pade (Certara inc.)A robotised 1546 compound
screen in a perfused 3D
microfluidic angiogenesis assay
Dr. Henriette Lanz (MIMETAS BV)

Coffee Break
S3
Education session on 3Rs

16:3016:55

Effort against "Challenge Contest"
to educate high school students
Prof. Nobuhiko Kojima(Yokohama City Univ.)

16:5517:20

Promotion of Proper Conduct ofAnimal Experiments
Dr. Ichiro Miyoshi(Japanese Association forLaboratory Animal Science)

17:2017:45

17:4518:00
18:3020:00

New technology to reduce thesacrifice of experimental animals
while practice anatomy
Mr. David Yoo (3D MediVision)

S4Oral Presentation from selected
posters

11:3011:55

11:5512:20

12:2014:00
14:0014:50
14:5015:20
15:2016:55

15:2015:45

15:4516:05

Max 9 Speakers(10 min presentation)
Speakers will be selected based on
posters submitted

Activities to increase educational
opportunities for 3Rs in Japan
Prof. Masaharu Akita(Kamakura Women's University)
Welcome dinner (Invited guest)(Room : CS Hotel & resort)

16:0516:30

16:3016:55

17:0018:00
18:00 -

3rd Day (12/16)

Halla Hall

Samda Hall

PL 2
Development of in vitro alternative assay methods for evaluation ofchemicals-mediated immunotoxicities considering comprehensivein vivo toxicities
Prof. Heo Yong (Daegu Catholic Univ., Korea)

Time

Coffee Break
S7
Medical device safety evaluation

S8
Organ-on-a-chip as an alternativemodel for drug screening

in vitro methods forbiocompatibility of medical
devices: achievements for
irritation and perspectives for skinsensitisation
Pellevoisin Christian (MatTek, France)
Pre-clinical safety testing platform
for medical devices
Dr. Rawiwan Maniratanachote(National Science and Technoloogy
Development Agency, Thailand)
Development and evaluationof alternative methods to skinsensitization tests for medicaldevices
Atsuko Miyazima (National Instituteof Health Sciences, Japan)

Research and Development ofMicrophysiological Systems inJapan supported by the AMEDMPS projectProf. Seiichi Ishida (Sojo Univ., Japan)
Brain-on-a-chip for neurotoxicity
tests
Prof. Sungho Ko (CHA University)
Human Mini-Brains for Neurological
DisordersProf. Hansang Cho(Sung Kyun Kwan Univ., Korea)

Identification of human blood-brain
barrier shuttles for brain drugdelivery using organ-on-a-chip
technology
Prof. Tae-Eun Park (UNIST, Korea)
PL 4
Human-relevant replacement methods are ready to take the place ofanimal experiments
Prof. M.A. Akbarsha (Autonomous, tiruchirappalli)
Banquet(Room : Ocean view(5F))

Development of alternative test toirritation tests for medical devices
Prof. Jae-Sung Kwon
(Yonsei Univ., Korea)

Samda Hall

09:3010:20

PL 5
Toward ideal prediction of human responses based on
physiological in vitro systems- Title: Japanese update Micro Physiologicals System (MPS)
Dr. Yasuaki Sakai (Univ. of Tokyo, Former president of JSAAE)

10:2010:40

Coffee BreakCoffee BreakS5
S6
Cosmetics - safety assessment of Zebrafish as an alternative modelscosmetics
for toxicology
Disease modeling of rare
Next Generation Risk Assessment
neurological disorders in zebrafish
to make safety decisions forProf. Cheol-Hee Kim (Chungnam
cosmetic ingredients
National University, Korea)
Dr. Matthew Dent (Unilever, UK)
Use of zebrafish embryo assay in
Next generation Risk Assessment
safety assessment of nanoparticles(NGRA) for skin sensitisation of
Dr. Wittaya Pimtong
cosmetic ingredients(Nanotec, Thiland)
Dr. Woo-Hyuck Choi (LG H&H, Korea)
Estimation of dermal permeationand systemic exposure ofThe use of Zebrafish teratogenicity
chemicals through the skin within pharmaceutical companies
alternative membrane and in silico assay
Dr. Kanako Mori (Astellas Pharma)model
Prof. Hiroaki Todo (Josai Univ., Japan)
Application and practice ofzebrafish embryonic development
Application of in vitro 3Dand hepatotoxicity model in
Reconstructed Human Epidermis
safety evaluation with mechanism
Models EpiKutis and EpiSkinTM toPredict Skin Irritation Potential on   exploration of traditional Chinese
medicine and natural products
Formulations
Dr. Hongtao Jin (Chinese Academy
Dr. Jing Sang (Zhejiang Institute forof Medical Sciences &Peking Union
Food and Drug Control, China)
Medical College)
Lunch seminar(Room : Halla Hall)
PL 3
High throughput screening and evaluation of chemical substancesby Omics
Prof. Xiaowei Zhang (Nanjing Univ., China)

Halla Hall

10:4012:20

S9Omics as an alternative model;
Case-studies and Perspectives

S10
Artificial intelligenceas analternative &predictive model

10:4010:45

Introduction: AFSA Cosmetics
Education and Training Program
Dr. Catherine Willett (HSI)

10:4511:05

Consumer Exposure
Dr. Ted Xing (L'Oréal)

Development, Validation,and Application of a Human
Reproductive Toxicity Prediction
Model Based on Adverse Outcome
Pathway,
Dr. Wei Shi (Jiangsu Province Ecologyand Environment Protection Key
Laboratory of Chemical Safety andHealth Risk, China)

11:0511:30

In silico tools and Read-AcrossDr. Jin Lin (Unilever, China)

Advanced Machine Learning in
Predictive Toxicology: Explainable AI
Dr. Igor Tetko(Helmholzt institue, Germany)

11:3011:55

Dosimetry: Internal Exposure
Dr. Yuan Gao (Procter &Gamble)

Pushing the boundaries of in silico
models beyond organic molecular
structure-centered chemical space
Dr. Hyun-Kil Shin
(KIT, Korea, Institute)

Regulatory LandscapeDr. Jay Ingram (Delphic HSE)

Development of in silico model forskin sensitization evaluation using
machine learning
Dr. Kaori Ambe
(Nagoya City Univ., Japan)

11:5512:20

12:20-

Closing ceremony(Room : Halla Hall)