SAFETY DATA SHEETSDS No.1050-24031

Date

December 15, 2021

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1. PRODUCT AND COMPANY IDENTIFICATIONPRODUCT NAME
： 4 Layer cleanup cartridge
NAME OF SUPPLIER： GL Sciences Inc.
ADDRESS： 22-1 Nishishinjuku 6-chome Shinjuku-ku Tokyo 163-1130, JapanCHARGE SECTION： International Sales Section
TELEPHONE No.
： +81-3-5323-6620
FACSIMILE No.
： +81-3-5323-6621
PRODUCT No.
： 1050-24031, 1050SDS No.
： 1050-24031
Research use only.
2. HAZARDS IDENTIFICATIONGHS CLASSIFICATIONLABEL ELEMENTS
HAZARD SYMBOLSIGNAL WORD
HAZARD STATEMENTS
H330
H314
H370
H372

： Acute toxicity - inhalation ： Category 2
Skin corrosion/irritation： Category 1A
Serious eye damage/eye irritation ： Category 1
Specific target organ toxicity (Single exposure)： Category 1 (respiratory organs)
Specific target organ toxicity (Repeated exposure)： Category 1 (respiratory organs)
Hazardous to the aquatic environment, short-term (acute)： Category 1
Hazardous to the aquatic environment, long-term (chronic)： Category 1：： Danger：
Fatal if inhaled
Cause severe skin burns and eye damage
Cause damage to organs (respiratory organs)
Cause damage to organs through prolonged or repeated exposure(respiratory organs)
H400
Very toxic to aquatic life
H410
Very toxic to aquatic life with long lasting effects
PRECAUTIONARY STATEMENTS ：[Prevention]
P260
Do not breathe dust/fume/gas/mist/vapors/spray.
P264
Wash hands thoroughly after handling.
P270
Do not eat, drink or smoke when using this product.
P271
Use only outdoors or in a well-ventilated area.
P273
Avoid release to the environment.
P280
Wear protective gloves/protective clothing/eye protection/face protection.
P284[In case of inadequate ventilation] wear respiratory protection.
[Response]
P301+P330+P331
IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303+P361+P353
IF ON SKIN or hair: Take off immediately all contaminated clothing. Rinse skin with water.
P304+P340
IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P305+P351+P338
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P308+P311
IF exposed or concerned: Call a POISON CENTER or doctor.

PRODUCT NAME ： 4 Layer cleanup cartridge
SDS No.1050-24031
P310
P314
P363
P391
[Storage]
P403+P233
P405[Disposal]
P501

Date

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Immediately call a POISON CENTER or doctor.
Get medical attention if you feel unwell.
Wash contaminated clothing before reuse.
Collect spillage.
Store in a well-ventilated place. Keep container tightly closed.
Store locked up.
Dispose of contents/container in accordance with all applicable regulations.

3. COMPOSITION/INFORMATION ON INGREDIENTSSUBSTANCE / MIXTURE： Mixture
COMMON CHEMICAL NAME
： 4 Layer cleanup cartridge
SYNONYMS： --CONTENTCHEMICALFORMULACAS RN.

TSCA
INVENTRY

EINECS No.

Silica gel

57 %

SiO 2

7631-86-9

Listed231-545-4

Sulfuric acid15 %H 2SO 47664-93-9

Listed231-639-5

Silver Nitrate

1.3 %

AgNO3

7761-88-8

Listed231-853-9

Potassium hydroxide

0.3 %

KOH

1310-58-3

Listed215-181-3

Sodium sulfate, anhydrous

26.4 %Na2 SO47757-82-6

Listed231-820-9

CHEMICAL NAME

4. FIRST AID MEASURES
GENERAL ADVICE： If fragments/respirable dust contacts with eyes or skin, wash off immediately
with soap and plenty of water. In the case of respirable dust and/or fumes, use
self-contained breathing apparatus and dust impervious protective suit. Use
personal protective equipment. If irritation persists, consult a physician.
INHALATION： Move victim to fresh air and gargle. If breathing is difficult, give oxygen.
If irritation persists, consult a physician.
SKIN CONTACT： Remove contaminated clothes and shoes, rinse skin with plenty of water orshower. Use soap to help assure removal. If irritation persists, consult aphysician.
EYE CONTACT： Remove any contact lenses at once. Flush eyes well with flooding large amountsof running water for at least 15 minutes. Assure adequate flushing by separating
the eyelids with sterile fingers. If irritation persists, consult a physician.
INGESTION： Rinse mouth, give plenty of water to vomit. Never give anything by mouth to an
unconscious person. Consult a physician.
MOST IMPORTANT SYMPTOMS AND EFFECTS： Shreds and dusts may cause irritation of mucous membranes, respiratory tract,skin and eyes.

5. FIRE FIGHTING MEASURES
EXTINGUISHING MEDIA： This product is noncombustible.
FIRE & EXPLOSION HAZARDS： Toxic and irritating dust, fumes or smoke may be emitted.
SPECIAL PROTECTIVE EQUIPMENT FOR FIRE FIGHTERS： Fireman should wear normal protective equipment (full bunker gear) andpositive-pressure self-contained breathing apparatus.
6. ACCIDENTAL RELEASE MEASURESPERSONAL PRECAUTIONS： Remove ignition sources and ventilate the area.
In case of insufficient ventilation, wear suitable respiratory equipment.
Avoid raising dust and avoid contact with skin and eyes.
ENVIRONMENTAL PRECAUTIONS： Prevent spills from entering sewers, watercourses or low areas.

PRODUCT NAME ： 4 Layer cleanup cartridge
SDS No.1050-24031

Date

METHODS FOR CLEANING UP

December 15, 2021

3/7 page： Do not touch spilled material without suitable protection. After material iscompletely picked up, wash the spill site with soap and water and ventilate thearea. Pull all wastes in a plastic bag for disposal and seal it tightly. Remove,clean, or dispose contaminated clothing.

7. HANDLING AND STORAGE
HANDLING： Avoid contact with eyes, skin, and clothing. Avoid prolonged or repeatedexposure. Handle material with suitable protection.
After using this product, dispose of contents/container in accordance with allapplicable regulations and appropriate ways.
： Store away from moisture and water in well-ventilated dry place.
Keep container tightly closed.
： Water, moisture

STORAGEINCOMPATIBLE PRODUCTS

8. EXPOSURE CONTROL/PERSONAL PROTECTION
ENGINEERING MEASURES： Use exhaust ventilation to keep airborne concentrations below exposure limits.
Use adequate ventilation.
VENTILATION： Local Exhaust ; Recommended, Mechanical(General) ; Recommended
CONTROL PARAMETERSCONTENTACGIH TLVOSHA PELNIOSH REL

Silica gel

3mg/m(as other respirable dust)

80 mg/m /%SiO(2)+2(as amorphous silica)

6 mg/m3(as amorphous silica)

Sulfuric acid

1mg/m 30.2mg/m 3

1mg/m 3

Silver Nitrate

0.01mg/m3 (as Ag)

0.01mg/m3 (as Ag)

0.01mg/m3 (as Ag)

Potassium hydroxide2mg/m 3Not established

2mg/m 3PERSONAL PROTECTIONRESPRATORY PROTECTION
HAND PROTECTION
EYE PROTECTION
SKIN PROTECTION

3

3： Safety mask
： Chemical resistant gloves： Safety glasses(goggles)： Protective clothing

9. PHYSICAL AND CHEMICAL PROPERTIESPHYSICAL STATE： Solid (powder)
COLOUR： white to light white grayish (Silver nitrate-impregnated silica gel)white to light yellowish (Sulfuric acid-impregnated silica gel, potassiumhydroxide silica gel)

ODOR
： Odorless
MELTING POINT / FREEZING POINT： No data available
BOILING POINT OR INITIAL BOILING POINT AND BOILING RANGE： No data available
FLAMMABILITY： No data available
LOWER AND UPPER EXPLOSION LIMIT / FLAMMABILITY LIMIT： No data available
FLASH POINT： No data available
AUTO-IGNITION TEMPERATURE： No data available
DECOMPOSITION TEMPERATURE： No data available
pH

KINEMATIC VISCOSITY
SOLUBILITY
PARTITION COEFFICIENT
n-octanol/water (log value)
VAPOUR PRESSURE： Strong acid (Sulfuric acid-impregnated silica gel in aquatic solution),strong base (Potassium hydroxide silica gel in aquatic solution)： Not applicable： Insoluble： No data available： No data available

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SDS No.1050-24031

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DENSITY AND/OR RELATIVE DENSITY： No data available
RELATIVE VAPOUR DENSITY： Not applicable
PARTICLE CHARACTERISTICS ： Not applicable
10. STABILITY AND REACTIVITY
REACTIVITY： It is easy to absorb moisture in the air, and carbon dioxide.
CHEMICAL STABILITY： Stable under recommended storage conditions.
CONDITION TO AVOID： Sunlight, heat, moisture, CO 2 , oxidizers, acids
INCOMPATIBLE MATERIALS： Strong oxidizers and strong acids
HAZARDOUS DECOMPOSITION PRODUCTS： NOx、SOx
11. TOXICOLOGICAL INFORMATIONACUTE TOXICITY (Oral)： Since the toxicity unknown component is 0.1% or more, it cannot be classified.
ACUTE TOXICITY (Dermal)： No data available
ACUTE TOXICITY (Inhalation)： No data available
SKIN CORROSION/IRRITATION ： Since sulfuric acid is 15% ≥ 1%, it corresponds to Category 1A.
EYE DAMAGE/EYE IRRITATION ： Since sulfuric acid is 15% ≥ 1%, it corresponds to Category 1A.
RESPIRATORY SENSITIZATION ： No data available(Sulfuric acid)： A description of serious eye damage with dissolution of the anterior chamber ofthe eye was observed in human accidents (ATSDR, 1998), moderate with 5%
solution to rabbit eyes, 10%. There is a description that strong irritation wasobserved in the liquid (SIDS, 2001) and the pH of this substance is 2 or less.
SKIN SENSITIZATION： No data available
GERM CELL MUTAGENICITY： Since the toxicity unknown component is 0.1% or more, it cannot be classified.
(Sulfuric acid)： There are no test data on the skin sensitization of sulfuric acid. Sulfuric acid has
been used industrially for decades, and while skin disorders due to skin irritation
are well known, there are no case reports of skin sensitization. A large amountof sulfate ions are present in the body (sulfate ions in serum are ~ 33 mmol / L,
50 times that in cells), but allergic reactions do not occur. In the metal sulfate
allergy test, it is presumed from the negative result of zinc sulfate that it may beallergic positive due to metal but negative for sulfate ion. From the above results,
it can be concluded that sulfuric acid is not allergic to humans (SIDS, 1998).
CARCINOGENICITY： No data available(Sulfuric acid)： In vivo, there are no test data using germ cells or somatic cells, and invitro mutagenicity tests show positive results only in a single-index (chromosomal aberration test) test system (ATSDR, 1998). Other indicators are negative.
(Potassium hydroxide)： There are no in vivo data on this substance, and in vitro, it is negativein the bacterial reversion mutation test and the chromosomal aberration t
est in cultured mammalian cells (SIDS (2004)). SIDS (2004) provides comprehensive information on this substance, sodium hydroxide (CAS No. 1
310-73-2), potassium chloride (CAS No. 7447-40-7), and potassium carbo
nate (CAS No. 584-08-7). We are evaluating the mutagenicity from. Thatis, sodium hydroxide has a negative result in the small nucleus test ofmouse bone marrow cells and the chromosomal aberration test of mouse
egg mother cells in vivo (SIDS (2004)), and in vitro, the high pH in themedium of the test substance and Except for the effects of osmotic pressure artifacts, sodium hydroxide, potassium chloride, and potassium carb
onate are bacterial reversion mutation tests, potassium chloride is a mouse phosphorformer test of cultured mammalian cells, and potassium carb
onate is a chromosomal abnormality in cultured mammalian cells. All tests are negative (SIDS (2004)). Based on the above, SIDS (2004) indicates that these substances are not considered to be genotoxic.
REPRODUCTIVE TOXICITY： No data available(Sulfuric acid)： Occupational exposure of inorganic strong acids, including sulfuric acid, to mistis classified as Group 1 by IARC (1992), A2 by ACGIH (2004), and K by NTP(2005). Respecting NTP evaluation, it is classified as Category 1. However,
sulfuric acid itself is classified into category 4 by DFGOT (vol.15, 2001), andneither institution classifies it as carcinogenic.
SPECIFIC TARGET ORGAN TOXICITY -Single exposure： Since sulfuric acid is 15% ≥ 10%, it corresponds to Category 1 (respiratory
system).

PRODUCT NAME ： 4 Layer cleanup cartridge
SDS No.1050-24031

Date

December 15, 2021

5/7 page(Sulfuric acid)： Airway irritation symptoms such as cough and shortness of breath have been
observed with low-dose inhalation exposure in humans (DFGOT, 2001), andacute effects such as cough, shortness of breath and blood sputum excretion
with high-dose exposure, as well as decreased lung function and A statementthat permanent effects such as fibrosis and emphysema were observed (ATSDR,
1998) and that pulmonary bleeding and dysfunction were observed after 8-hour
inhalation exposure in guinea pigs (ATSDR, 1998).
(Silver nitrate)： This substance is corrosive and airway irritant (ATSDR (1990), PATTY (6th, 2012)). In humans, airway mucosa irritation due to inhaled dust expo
sure and oral acute poisoning symptoms include burning sensation and pain in the mouth, salivation, vomiting, abdominal pain, diarrhea, severe gastroenteritis, decreased blood pressure, decreased respiratory rate, anddizziness. , Convulsions, medial muscle paralysis, coma, central nervous
system disorders, and death have been reported (HSDB (Access on September 2014)). There are no experimental animal data.
SPECIFIC TARGET ORGAN TOXICITY -Repeated exposure： Since sulfuric acid is 15% ≥ 10%, it corresponds to Category 1 (respiratory
system).
(Sulfuric acid)： In the 28-day inhalation exposure test in rats of SIDS (2001), cell proliferation
was observed in the laryngeal mucosa within the guidance value range of
Category 1, and in the 14-139-day repeated inhalation exposure test in guinea
pigs of ATSDR (1998), Category 1 Airway and lung disorders such as nasal
septal edema, pulmonary emphysema, aerobic lung, bronchiolar congestion,
edema, bleeding, thrombosis, and lung fineness in a 78-week inhalation
exposure study in cynomolgus monkeys at concentrations within the guidance
range. Histological changes such as cell hyperplasia in the bronchioles and wall
thickening were observed at doses (0.048 mg / L, 23.5 Hr / Day) within theguidance value range of Category 1.
(Silver nitrate)： At a silver nitrate and silver oxide manufacturing plant, 25 out of 30 wor
kers who have been exposed to silver dust for less than 1 year to morethan 10 years have upper respiratory tract irritation (sneezing, runny nose, stuffy nose, sore throat). , The same 10 people reportedly complaine
d of abdominal pain (severe pain reduced by antioxidants) (ATSDR (1990), ACGIH (7th, 2001)). Of these, abdominal pain may be due to mucos
al irritation caused by oral ingestion of part of the dust, and in a small
number of symptoms (1/3 of the total), other gastrointestinal symptoms s
uch as diarrhea and vomiting are also described. It was thought that it should not be the target of the target organ.
On the other hand, in experimental animals, in a test in which 222 mg Ag / kg /day (equivalent to 349.6 mg / kg / day) of this substance was administered torats by drinking water for 37 weeks, an increase in mortality was observed after
23 weeks, but in the eyes There is no description of organ toxicity other thansilver disease (ACGIH (7th, 2001)), and in a study in which 89 mg Ag / kg / day(equivalent to 140 mg / kg / day) was administered to rats by drinking water for
9 months, left Although there is a description that ventricular hypertrophy wasobserved (ATSDR (1990), ACGIH (7th, 2001)), the effects on the cardiovascularsystem have not been reported in human and other animal studies, and thisresult is reliable. It is said that there is no such thing (ATSDR (1990)). In addition,
there are no data available for classification in laboratory animals.
ASPIRATION TOXICITY： Since the kinematic viscosity is unknown, it cannot be classified.
(Potassium hydroxide)： Death cases in which this substance was orally ingested for unintentional or
suicide purposes, including a description that some of the causes of death
include aspiration from the esophagus to the trachea and pneumonia (ACGIH(7th, 2001)), and the alkaline respiratory tract. There is a description that
aspiration to the larynx causes fatal injury to the pharynx, trachea / bronchi, andlungs (SIDS (2004)).
12. ECOLOGICAL INFORMATION
Hazardous to the aquatic environment -Acute hazard： Category 1 x Toxicity multiplier is 130.0%, which corresponds to Category 1
because it is above the concentration limit (25%).
(Sulfuric acid)： Fish (bluegill) 96 hours LC50 (pH 3.25-3.5) = 16-28 mg / L (OECD SID
S: 2001).
(Silver nitrate)： 48 hours EC50 = 0.0014 mg / L (0.0009 mg Ag / L) (CICADs 44, 2002) bycrustaceans (Daphnia magna).

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Hazardous to the aquatic environment -Chronic hazard： Category 1 x Toxicity multiplier is 145.0%, which corresponds to Category 1
because it is above the concentration limit (25%).
(Sulfuric acid)： Using chronic toxicity data, the mediopassive voice of inorganic compoun
ds in the environment is unknown, but the 45-day NOEC (growth) (pH 6.
0) = 0.025 mg / L (OECD SIDS: 2001) for fish (mosquitofish). Since mosquitofish are ovoviviparous, the results cannot be used for classification,
but they have a large effect on the growth of the target substance andare expected to have the same or higher toxicity in other fish species.
When acute toxicity data are used for nutritional stages for which chronic
toxicity data are not available, the environmental kinetics of inorganic compounds are unknown, but 24-hour LC50 = 29 mg / L (OECD SIDS) for
crustaceans (Daphnia magna). : 2001).
(Silver nitrate)： When using chronic toxicity data, the environmental dynamics of inorgani
c compounds are unknown, and 60-day LOEC = 0.00016 mg / L (CICAD
s 44, 2002) for fish (rainbow trout).
When acute toxicity data are used for nutritional stages for which chronic toxicity
data are not available, the environmental kinetics of inorganic compounds is
unknown, and 48 hours EC50 = 0.0014 mg / L (0.0009 mg) of crustaceans(Daphnia magna). Ag / L) (CICADs 44, 2002).
BIODEGRADABILITY： No data available.
BIOACCUMULATIVE POTENTIAL ： No data available
MOBILITY IN SOIL
： No data available
Hazardous to the ozone layer： This substance is not listed in Annexes to the Montreal Protocol.
13. DISPOSAL INFORMATION
Dispose in a hazardous-waste site in accordance with all applicable regulations. Any disposal practice must be incompliance with country, local, state, and federal laws and regulations (contact country, local or state environment
agency for specific rules).
14. TRANSPORT INFORMATIONInternational Regulations
Marine regulatory information： Comply the provisions of IMO.
UN Number： 2923
Proper Shipping Name
： CORROSIVE SOLID, TOXIC, N.O.S.
Class
： 8
Sub Risk： 6.1
Packing Group： II
Marine Pollutant： Not applicable
Aviation regulatory information： Comply the previsions of ICAO/IATA.
UN Number： 2923
Proper Shipping Name
： CORROSIVE SOLID, TOXIC, N.O.S.
Class
： 8
Sub Risk： 6.1
Packing Group： II
Emergency Response Guide Number ： 154
15. REGULATORY INFORMATIONFor classification and labeling of chemicals in accordance with the applicable rules and regulations in the EU or eachcountry, refer to GHS classification of this product (See Section 2).
US REGULATION
EU REGULATION： OSHA HCS 2012/29 CFR 1910.1200： CLP Regulation ((EC) No. 1272/2008)

PRODUCT NAME ： 4 Layer cleanup cartridge
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Date

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16. OTHER INFORMATIONNOTICE:The information contained in the SDS description is applicable exclusively to the chemical substance identified herein
and for its intended use as an analytical reference standard or reagent and to the unit quantity intended for that
purpose. The information does not relate to, and may not be appropriate for, any application or larger quantity of thesubstance described. Our products are intended for the use by individuals possessing sufficient technical skill andqualification on use the material potential hazardous chemical. Accordingly, no representation or warranty, express
or implied, with respect to merchantability and fitness for a particular purpose is made with respect to the information
contained herein.
Attention:
This product in terms of chemical identity and the unit amount provide is intended for use in chemical analysis andnot for human consumption, nor any other purpose.