EU化粧品指令/化粧品に関する規則 1223/2009
別表II 及び別表IIIより（2021.5.26バージョン）
REGULATION (EC) No 1223/2009 OF THE EUROPEAN PARLIAMENT AND OF THE COUNCIL of 30 November 2009 on cosmeticproducts
https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=CELEX:02009R1223-20160812&from=EN
ANNEX II LIST OF SUBSTANCES PROHIBITED IN COSMETIC PRODUCTS『別表II 化粧品への配合が禁止の物質』から”fragrance”で検索された化学物質32種類を抜粋
Ref

No. Substance identificationa

Chemical name/INN

CAS No.

EC No.

bcd423

Alanroot oil (Inula helenium L.), when used as a fragrance ingredient

97676-35-2424

Benzyl cyanide, when used as a fragrance ingredient140-29-4

205-410-5425

Cyclamen alcohol, when used as a fragrance ingredient4756-19-8

225-289-2

426

Diethyl maleate, when used as a fragrance ingredient141-05-9

205-451-9

427

3,4-Dihydrocoumarin, when used as a fragrance ingredient119-84-6

204-354-9

428

2,4-Dihydroxy-3-methylbenzaldehyde, when used as a fragrance ingredient6248-20-0

228-369-5

429

3,7-Dimethyl-2-octen-1-ol (6,7-Dihydrogeraniol), when used as a fragrance ingredient40607-48-5

254-999-5

4304,6-Dimethyl-8-tert-butylcoumarin, when used as a fragrance ingredient

17874-34-9

241-827-9

431

Dimethyl citraconate, when used as a fragrance ingredient617-54-9

432

7,11-Dimethyl-4,6,10-dodecatrien-3-one (Pseudomethylionone), when used as a fragrance ingredient26651-96-7

247-878-3

433

6,10-Dimethyl-3,5,9-undecatrien-2-one (Pseudoionone), when used as a fragrance ingredient141-10-6

205-457-1

434

Diphenylamine, when used as a fragrance ingredient122-39-4

204-539-4

435

Ethyl acrylate, when used as a fragrance ingredient140-88-5

205-438-8

1 of 8436

Fig leaf absolute (Ficus carica L.), when used as a fragrance ingredient68916-52-9

437trans-2-Heptenal, when used as a fragrance ingredient

18829-55-5

242-608-0

438trans-2-Hexenal diethyl acetal, when used as a fragrance ingredient67746-30-9

266-989-8

439trans-2-Hexenal dimethyl acetal, when used as a fragrance ingredient

18318-83-7

242-204-4

440

Hydroabietyl alcohol, when used as a fragrance ingredient13393-93-6

236-476-3

441

6-Isopropyl-2-decahydronaphthalenol, when used as a fragrance ingredient34131-99-2

251-841-7

442

7-Methoxycoumarin, when used as a fragrance ingredient531-59-9

208-513-3443

4-(4-Methoxyphenyl)-3-butene-2-one (Anisylidene acetone), when used as a fragrance ingredient943-88-4

213-404-9444

1-(4-Methoxyphenyl)-1-penten-3-one (alpha-Methylanisylideneacetone), when used as a fragrance ingredient104-27-8

203-190-5

445

Methyl trans-2-butenoate, when used as a fragrance ingredient623-43-8

210-793-7

446

7-Methylcoumarin, when used as a fragrance ingredient2445-83-2219-499-3

447

5-Methyl-2,3-hexanedione (Acetyl isovaleryl), when used as a fragrance ingredient

13706-86-0

237-241-8

448

2-Pentylidenecyclohexanone, when used as a fragrance ingredient

25677-40-1

247-178-8

449

3,6,10-Trimethyl-3,5,9-undecatrien-2-one (Pseudo-Isomethyl ionone), when used as a fragrance ingredient1117-41-5

214-245-8

450

Verbena essential oils (Lippia citriodora Kunth.) and derivatives other than absolute when used as a fragrance
ingredient8024-12-2

285-515-0

1133

Costus root oil (Saussurea lappa Clarke), when used as a fragrance ingredient8023-88-91134

7-Ethoxy-4-methylcoumarin, when used as a fragrance ingredient87-05-8

201-721-5

1135

Hexahydrocoumarin, when used as a fragrance ingredient700-82-3

211-851-4

1136

Exudation of Myroxylon pereirae (Royle) Klotzsch (Peru balsam, crude) when used as a fragrance ingredient8007-00-9

232-352-8▼M1

2 of 8

ANNEX III LIST OF SUBSTANCES WHICH COSMETIC PRODUCTS MUST NOT CONTAIN EXCEPT SUBJECT TO THE
RESTRICTIONS LAID DOWN (2021.5.26)
化粧品指令『別表III 法律によって制限される場合を除いて化粧品に配合することを禁止する物質』297種類の化学物質のリストからアレルゲンとしてラベルに表示しなければならない26の香料物質を抜粋*（日本語表記は訳者）。26の物質には含まれないが”fragrance”で検索された化学物質5種類も付記。
*26のアレルゲン香料物質は化粧品指令1223/2009 Article 19(1)に定められ、表中のOtherの項に記載されている。2021年に欧州消費者安全性科学委員会(SCCS)が出した意見書（https://ec.europa.eu/health/scientiﬁc̲committees/consumer̲safety/docs/sccs̲o̲102.pdf ）P73-77も参照

Chemicalname/INN

Name ofCAS
Common No.
Ingredients
Glossary

EC No. Product
Maximum
type, body concentration inparts
ready for use
preparation

Other

Wordingofconditio
ns of useandwarnings

bcehiRef Substance identification
no.

aRestrictionsdf

67 2Amyl
122-40- 204-54
1-5
Benzylideneh cinnamal 7
アミルシンナ
eptanalThe presence of the substance must be indicated in the list of ingredientsreferred to in Article 19(1)(g) when its concentration exceeds:— 0,001 % in leave-on products— 0,01 % in rinse-oﬀ productsム

45 Benzyl
alcohol (7)BenzylAlcohol

100-51- 202-85 (a) Solvent
9-96

ベンジルアル(b) Fragrance/aromaticcompositions/their raw
materials

コール

69 Cinnamyl
alcohol

Cinnamylalcohol

For purposes other than inhibiting the development of microorganisms in theproduct. This purpose has to be apparent from the presentation of the product.
(b) The presence of the substance must be indicated in the list of ingredientsreferred to in Article 19(1)(g) when its concentration exceeds:— 0,001 % in leave-on products— 0,01 % in rinse-oﬀ products.

104-54- 203-21
2-31The presence of the substance must be indicated in the list of ingredientsreferred to in Article 19(1)(g) when its concentration exceeds:— 0,001 % in leave-on products— 0,01 % in rinse-oﬀ products5392-4 226-39
4-60-5The presence of the substance must be indicated in the list of ingredientsreferred to in Article 19(1)(g) when its concentration exceeds:— 0,001 % in leave-on products— 0,01 % in rinse-oﬀ products

シンナミアルコール

70 3,7Citral
Dimethyl-2,6- シトラール
octadienalg

3 of 8

71 Phenol, 2methoxy-4(2-propenyl)

Eugenol
オイゲノール97-53-0 202-58

The presence of the substance must be indicated in the list of ingredientsreferred to in Article 19(1)(g) when its concentration exceeds:— 0,001 % in leave-on products— 0,01 % in rinse-oﬀ products

9-1

72 7Hydroxycit 107-75- 203-51 (a) Oral
8-7products
Hydroxycitron ronellal
5ellal(b) Otherproducts

ハイドロキシシトロネラー(b) 1.0%(a) (b)
The presence of the substance must be indicated in the list of ingredientsreferred to in Article 19(1)(g) when its concentration exceeds:— 0,001 % in leave-on products— 0,01 % in rinse-oﬀ products

ル

73 Phenol, 2methoxy-4(1-propenyl)

Isoeugenol 97-54-1 202-59 (a) Oral/5932-6 0-7/227 products-678-2イソオイゲ
8-3(b) Otherproducts

ノール

74 2-Pentyl-3Amylcinna 101-85- 202-98
2-8
phenylprop-2 myl
9-en-1-ol
alcohol
アミルシンナ(b) 0.02%(a) (b)The presence of the substance must be indicated in the list of ingredientsreferred to in Article 19(1)(g) when its concentration exceeds:— 0,001 % in leave-on products— 0,01 % in rinse-oﬀ products

The presence of the substance must be indicated in the list of ingredientsreferred to in Article 19(1)(g) when its concentration exceeds:— 0,001 % in leave-on products— 0,01 % in rinse-oﬀ products

ミアルコール75 Benzyl
salicylate

Benzylsalicylate

118-58- 204-26
2-91

The presence of the substance must be indicated in the list of ingredientsreferred to in Article 19(1)(g) when its concentration exceeds:— 0,001 % in leave-on products— 0,01 % in rinse-oﬀ products104-55- 203-21
3-92

The presence of the substance must be indicated in the list of ingredientsreferred to in Article 19(1)(g) when its concentration exceeds:— 0,001 % in leave-on products— 0,01 % in rinse-oﬀ products

77 2H-1CoumarinBenzopyran-2
クマリン-one

91-64-5 202-08

The presence of the substance must be indicated in the list of ingredientsreferred to in Article 19(1)(g) when its concentration exceeds:— 0,001 % in leave-on products— 0,01 % in rinse-oﬀ products

78 2,6Octadien-1ol, 3,7dimethyl-,(2E)-

106-24- 203-37
7-11

The presence of the substance must be indicated in the list of ingredientsreferred to in Article 19(1)(g) when its concentration exceeds:— 0,001 % in leave-on products— 0,01 % in rinse-oﬀ products

サリチル酸ベンジル

76 2-Propenal,3-phenyl-Cinnamal
シンナム

Geraniol
ゲラニオール

6-7

4 of 8

79 3 and 4-(4Hydroxy-4methylpentyl)
cyclohex-3ene-1carbaldehyde

Hydroxyis
ohexyl 3cyclohexe
necarboxald
ehyde

51414- 257-18
25-6/31 7-9/250
906-04- -863-4
4＊ヒドロキシメチルペンチルシクロヘキセンカルボアルデヒド＊和名はH欄

80 4Anise
Methoxybenz alcoholyl alcohol

The presence of the substance must be indicated in the list of ingredientsreferred to in Article 19(1)(g) when its concentration exceeds:— 0,001 % in leave-on products— 0,01 % in rinse-oﬀ products105-13- 203-27
3-65The presence of the substance must be indicated in the list of ingredientsreferred to in Article 19(1)(g) when its concentration exceeds:— 0,001 % in leave-on products— 0,01 % in rinse-oﬀ products

81 2-Propenoic Benzyl
103-41- 203-10
9-3acid, 3cinnamate 3
phenyl-,phenylmethyl ベンジルシン
ナメート
ester

The presence of the substance must be indicated in the list of ingredientsreferred to in Article 19(1)(g) when its concentration exceeds:— 0,001 % in leave-on products— 0,01 % in rinse-oﬀ products

82 2,6,10Farnesol
4602-8 225-00
4-1
Dodecatrien4-0
1-ol, 3,7,11- ファネソール
trimethyl-

The presence of the substance must be indicated in the list of ingredientsreferred to in Article 19(1)(g) when its concentration exceeds:— 0,001 % in leave-on products— 0,01 % in rinse-oﬀ products

83 2-(4-tertButylbenzyl)propionaldehy
deButylphen 80-54-6 201-28
9-8yl
methylpro
pionalThe presence of the substance must be indicated in the list of ingredientsreferred to in Article 19(1)(g) when its concentration exceeds:— 0,001 % in leave-on products— 0,01 % in rinse-oﬀ products* 2-(4-tert- ブチルベンジル) プロピオンアルデヒド

84 1,6Octadien-3ol, 3,7dimethyl-Linalool

78-70-6 201-13

The presence of the substance must be indicated in the list of ingredientsreferred to in Article 19(1)(g) when its concentration exceeds:— 0,001 % in leave-on products— 0,01 % in rinse-oﬀ products

85 Benzyl
benzoate

Benzylbenzoate120-51- 204-40
2-94

The presence of the substance must be indicated in the list of ingredientsreferred to in Article 19(1)(g) when its concentration exceeds:— 0,001 % in leave-on products— 0,01 % in rinse-oﬀ products

86 Citronellol/(±) Citronellol 106-22- 203-37-3,79/2648 5-0/247
dimethyloct-6 シトロネロー 9-01-0 -737-6
ル-en-1-ol

The presence of the substance must be indicated in the list of ingredientsreferred to in Article 19(1)(g) when its concentration exceeds:— 0,001 % in leave-on products— 0,01 % in rinse-oﬀ products

アニシルアルコール＊和名はH欄4-4リナロール

安息香酸ベンジル

5 of 8

87 2Hexyl
Benzylideneo cinnamalctanal

101-86- 202-98
3-30The presence of the substance must be indicated in the list of ingredientsreferred to in Article 19(1)(g) when its concentration exceeds:— 0,001 % in leave-on products— 0,01 % in rinse-oﬀ products5989-2 227-81
3-57-5The presence of the substance must be indicated in the list of ingredientsreferred to in Article 19(1)(g) when its concentration exceeds:— 0,001 % in leave-on products— 0,01 % in rinse-oﬀ products
Peroxide value less than 20 mmoles/L (16)ヘキシルシンナム

88 dLimonene
Limonene(4R)-1-Methyl-4- リモネン
(1methylethenyl) cyclohexene

89 Methyl Oct-2- Methyl 2- 111-12- 203-83
6-6ynoate;
Octynoate 6Methyl
heptinecarbonate
メチルヘプチン炭酸塩

90 3-Methyl-4alpha(2,6,6Isomethyl
trimethyl-2ionone
cyclohexen-1-yl)-3buten-2-one

127-51- 204-84
56-3(a) Oralproducts(b) Otherproducts(b) 0,01 % when(a) (b)used alone
The presence of the substance must be indicated in the list of ingredients
When present inreferred to in Article 19(1)(g) when its concentration exceeds:
combination with
— 0,001 % in leave-on products
methyl octine— 0,01 % in rinse-oﬀ products
carbonate, thecombined level inthe finishedproduct shall not
exceed 0,01 % (ofwhich methyl octine
carbonate shall not
be more than0,002 %)The presence of the substance must be indicated in the list of ingredientsreferred to in Article 19(1)(g) when its concentration exceeds:— 0,001 % in leave-on products— 0,01 % in rinse-oﬀ products＊3- メチル -4- (2,6,6,- トリメチル -2-シクロヘキセン -1- イル)＊和名はH欄

91 Oak moss
extract

Evernia
prunastri
オークモス抽出物 extract

90028- 289-86
68-51-3

The presence of the substance must be indicated in the list of ingredientsreferred to in Article 19(1)(g) when its concentration exceeds:— 0,001 % in leave-on products— 0,01 % in rinse-oﬀ products

Evernia
90028- 289-86
furfuracea 67-40-8
ツリーモス抽出物 extract

The presence of the substance must be indicated in the list of ingredientsreferred to in Article 19(1)(g) when its concentration exceeds:— 0,001 % in leave-on products— 0,01 % in rinse-oﬀ products

92 Treemoss
extract

6 of 8アレルゲンとしてラベルに表示義務のある26の香料物質には含まれないが、Annex III表中で”Fragrance”で検索された5つの物質Reference
numbera96

Substance identification
Chemicalname/INN

Name of Common
Ingredients GlossaryCASnumberEC
numberProduct type, Maximum concentration inbody parts
ready for use preparation

Other

Wording ofconditions of use
and warnings

bcdefhi5-tert-Butyl-2,4,6-trinitro-mxylene

Restrictions

gMusk xylene 81-15-2 201-329-4 All cosmetic products, with the exception of oralproducts

97 4'-tert-Butyl-2',6'-dimethyl-3',5'dinitroacetophenone

Muskketone

102 1,2-Dimethoxy-4-(2propenyl)-benzene

202-223-0 Fine fragrance

0,01 %

Eau de toilette

4%

Fragrance cream2%

Methyl eugenol 93152(a) 1,0 % in fine fragrance(b) 0,4 % in eau de toilette(c) 0,03 % in otherproducts

81-14- 201-328- All cosmetic products, with the exception of oral (a) 1,4 % in fine
19products
fragrance(b) 0,56 % in eau detoilette(c) 0,042 % in otherproducts

Other leave-on products and oral
products
Rinse-oﬀ products

0,0002%1%▼M1
182 1-(5,6,7,8-Tetrahydro-3,5,5,6,8,8,hexamethyl-2-naphthyl)ethan-1-one (AHTN)

Acetylhexamethyltetralin21145-77-7 /
1506-02-1

7 of 8244-240-6 /216-133-4

All cosmetic products with the
exception of oral products(a) leave-on products:
0,1 %
except:hydroalcoholic products:
1%
fine fragrance: 2,5 %fragrance cream: 0,5 %(b) rinse-oﬀ products:
0,2 %

297
◄

2-(2Ethoxydiglycol
Ethoxyethoxy)
ethanol
Diethylene
GlycolMonoethyl
Ether (DEGEE)

111- 203-91 (a) Oxidative hair dye
90-0 9-7products(a) 7 % (a) to (e):The level of(b) Non-oxidative hair dye (b) 5 % ethylene glycol
impurity inproducts
Ethoxydiglycol(c) Rinse-oﬀ products(c) 10must be ≤ 0,1 %.
other than hair dye%
Not to be used inproducts
eye products and(d) Other non-spray(d) 2,6 oral products.
cosmetic products%(e) The following spray(e) 2,6
products: fine fragrances, %hair sprays,
antiperspirants anddeodorants

8 of 8