HOSOKAWA POWDER TECHNOLOGY FOUNDATION
Shoudai-Tajika 1-9, Hirakata, Osaka, 573-1132 Japan
Tel: + 81-72-867-1686 Fax: + 81-72-867-1658 E-mail: contact_zainq@hmc.hosokawa.com URL: www.kona.or.jp

PROCESS TECHNOLOGIES FOR TOMORROWINVITATION TO THE
EUROPEAN POWDER TECHNOLOGY SYMPOSIUM 2014
at HOSOKAWA ALPINE Aktiengesellschaft, on 29th September 2014 in Augsburg, Germany.

TRENDS IN POWDER TECHNOLOGY FOR
NEW FUNCTIONAL MATERIALSNew construction materials, applications and products result from newtechnologies for the production of ultrafine powders and nanoparticles.
Process technology can influence the product properties in a targetedmanner via the particle size, geometry and particle surface. To this end,
the R&D, production and quality control departments make use of
new instrumentation, machine concepts, sensors and state-of-the-art
automation technology. The Hosokawa European Powder Technology
Symposium deals with these new technologies and future trends, and offers:››4 striking presentations from experienced scientists and engineers on
future developments in powder processing applications and equipment,››The opportunity to meet and get acquainted with managers and experts
from other powder processing companies,››Time for discussions with speakers and visitors,››and a coach transfer to the POWTECH exhibition at Nuremberg on Tuesdaymorning.
The symposium addresses scientists, engineers and decision-makers fromcompanies and institutes specialised in the manufacture and processing offine powders. All papers will be in English. Participation is free of charge
but requires timely registration.
The symposium will take place on the premises of
HOSOKAWA ALPINE Aktiengesellschaft:Peter-Doerfler-Str. 13-25, 86199 Augsburg, Germany

HOSOKAWA POWDER TECHNOLOGY FOUNDATION
Shoudai-Tajika 1-9, Hirakata, Osaka, 573-1132 Japan
Tel: + 81-72-867-1686 Fax: + 81-72-867-1658 E-mail: contact_zainq@hmc.hosokawa.com URL: www.kona.or.jp

PROCESS TECHNOLOGIES FOR TOMORROWEUROPEAN POWDER TECHNOLOGY SYMPOSIUM 2014
MONDAY, 29TH SEPTEMBER 2014

13:30		Welcome address		
Y. Hosokawa, President of Hosokawa Powder Technology Foundation
13:45		Overview and Prospects of Powder Technology		
Prof. W. Peukert, Erlangen University
14:30		Advancements, Challenges and Trends in Size Reduction Technology for		Pharmaceutical Applications, 					Dr. M. Juhnke, Novartis AG, Basel
15:15		Coffee Break
15:45		Design of Powder Processing Equipment by Computer Simulation		
Prof. J. Kano, Tohoku University
16:30		Computerization of Powder Processing Systems		
Dr. S. Sander, G. Kiederle, HOSOKAWA ALPINE AG
17:15		Closing remarks		
P. Krieg, President of HOSOKAWA ALPINE AG

POWTECH + TechnoPharm 2014
TUESDAY, 30TH SEPTEMBER 2014

Visit of the World-Leading trade fair for processing, analysis and handling of powder and bulk solids
and the booth of HOSOKAWA MICRON Group.				
08:00		Coach departure from HOSOKAWA ALPINE to Nuremberg.
10:30		Approximate arrival time at the Nuremberg Exhibition Centre. Addmission tickets provided by us.
10:30 - 11:30 Tour of the HOSOKAWA MICRON Group exhibition stand: explanation of the exhibited 				machines and their application areas. Afterwards, you will have the opportunity to look around		the two trade fairs on your own.
17:00 - 19:30 Return coach trip to Augsburg

HOSOKAWA POWDER TECHNOLOGY FOUNDATION
Shoudai-Tajika 1-9, Hirakata, Osaka, 573-1132 Japan
Tel: + 81-72-867-1686 Fax: + 81-72-867-1658 E-mail: contact_zainq@hmc.hosokawa.com URL: www.kona.or.jp

PROCESS TECHNOLOGIES FOR TOMORROWHOSOKAWA EUROPEAN POWDER TECHNOLOGY SYMPOSIUM 2014
MESSAGE FROM THE ORGANISER

It is a great pleasure to announce that the Hosokawa European Powder
Technology Symposium entitled ”Trends in Powder Technology for New
Functional Materials” will be held at HOSOKAWA ALPINE AG on Monday
29th of September, 2014, as a part of special events to celebrate the 20thanniversary of the Hosokawa Powder Technology Foundation. This foundation
was established in Japan in 1991 for the purpose of promoting science andtechnology in the field of powder and particle processing and characterisationon the basis of the fund donated by the late Mr Masuo Hosokawa. It annuallypresents the “KONA Award” to a prominent researcher with an excellent
contribution to the advancement in this field and supports active researchers
by financial funding.
This symposium is the first one to be held outside Japan by our foundation, which aims to promote theexchange of technical information and knowledge among European and Japanese researchers and engineers
engaged in the work of handling powder and particles.
I hope that this symposium will bring the participants new tips and ideas which will lead to innovative andfruitful R&D and engineering work in academia and industry.

Yoshio Hosokawa
President
Hosokawa Powder Technology Foundation

HOSOKAWA POWDER TECHNOLOGY FOUNDATION
Shoudai-Tajika 1-9, Hirakata, Osaka, 573-1132 Japan
Tel: + 81-72-867-1686 Fax: + 81-72-867-1658 E-mail: contact_zainq@hmc.hosokawa.com URL: www.kona.or.jp

PROCESS TECHNOLOGIES FOR TOMORROW

ABSTRACT:OVERVIEW AND PROSPECTS OF POWDER TECHNOLOGY
Wolfgang Peukert, Institute of Particle Technology, University Erlangen, Germany, wolfgang.peukert@fau.deSource: English Wikimedia commons - Author: meharris - Date:2001/05/10

Advanced materials with properties tailored on
the molecular and mesoscales are expected tostimulate evolutionary advances and revolutionary
breakthroughs in emerging key-technology areas suchas information and communication as well as catalysis,energy and transportation. The creation of tailor-madeproducts made from nanoscale building blocks is oneof the great challenges in the manufacture of new
functional materials. Nanoparticles as building blocks
are controlled by surface and interparticle forces. The
microscopic control of the interfaces is therefore a
key requirement for product design and formulationof nanoparticles. We present a multi-scale view fromthe molecular level towards macroscopic effects andapplications, e.g. in additives manufacturing, printableelectronics or the life sciences. A highly relevant
question is how the product quality evolves throughout
the process and how the process structure-functions
influence the product quality, i.e. the related structureproperty functions.

Fundamental studies open many applications. These
include mechanochemical effects, the dispersion ofsemi-conducting nanoparticles for the production offunctional conductive films, translucent ceramic tapes
and bioglass from which apatite can be grown forbone replacement. A novel process to produce polymer
particles below 5 µm for additives manufacturing
is introduced. Molecularly thin layers of grapheneand boron-nitride sheets have been produced fromcommercial graphite powder under mild milling
conditions. In all these applications, new challenges
need to be solved. These include multi-dimensional
particle characterisation beyond size, i.e. shape, surface,composition and characterisation really do matter.
Today, powder technology is a key technology for theproduction of new functional materials.

HOSOKAWA POWDER TECHNOLOGY FOUNDATION
Shoudai-Tajika 1-9, Hirakata, Osaka, 573-1132 Japan
Tel: + 81-72-867-1686 Fax: + 81-72-867-1658 E-mail: contact_zainq@hmc.hosokawa.com URL: www.kona.or.jp

PROCESS TECHNOLOGIES FOR TOMORROW

ABSTRACT:ADVANCEMENTS, CHALLENGES AND TRENDS IN SIZE REDUCTIONTECHNOLOGY FOR PHARMACEUTICAL APPLICATIONS
Michael Juhnke, Novartis Pharma AG, Basel, Switzerland

Engineering and control of drug particle size is ofparamount importance throughout drug development
and manufacturing to ensure reliable performance
during pharmaceutical manufacturing, as well as
consistent product shelf-life, administration and invivo behavior.
Size reduction techniques are frequently applied toengineer drug particle size after chemical synthesis
and isolation techniques. Standard platform milling
technologies in dry and wet mode are preferred,targeting for particle sizes of few 100 µm to about
100 nm, and processing multiple drug compounds
per platform technology from several gram batch
size at preclinical development stage up to about 500
kilogram batch size for commercial manufacturing.
The presentation will provide an overview on therequirements for engineered drug particle sizes andstandard platform milling technologies, advancements
for the processing of highly-active drug compounds,
application of rotor-impact and wet-media milling
technology during drug development, challenges
regarding drug processing and drug product quality,
as well as trends for size reduction techniques during
drug development and commercial manufacturing.

HOSOKAWA POWDER TECHNOLOGY FOUNDATION
Shoudai-Tajika 1-9, Hirakata, Osaka, 573-1132 Japan
Tel: + 81-72-867-1686 Fax: + 81-72-867-1658 E-mail: contact_zainq@hmc.hosokawa.com URL: www.kona.or.jp

PROCESS TECHNOLOGIES FOR TOMORROW

ABSTRACT:DESIGN OF POWDER PROCESSING EQUIPMENT BY COMPUTER SIMULATION
Junya Kano and Shingo Ishihara, Institute of Multidisciplinary Research for Advanced Materials,Tohoku University, Japan, kano@tagen.tohoku.ac.jp
Computer simulation in powder technology has
recently developed in a remarkable way and isapplied in different unit operations such as grinding,agglomeration, mixing and classification. First of all,
we have focused on the grinding of solid particles.
Grinding is one of the most important unit operationsin powder processing, and it has been carried out inmany fields of science and industry.
Fine grinding operations can be done using several
types of media mills such as tumbling, vibration,planetary and stirred mills. We have numericallysimulated the ball motion in media milling by theDistinct Element Method (DEM), and also developed
a method to predict the particle size during the batch
grinding process. We recently developed a new direct
simulation method of the breakage phenomena of asolid particle. The new simulation method has been
named Advanced Distinct Element Method (ADEM),and ADEM is able to simulate the behavior of thenon-spherical particles. ADEM has been applied tosieving and powder mixing as well, and the modellingof the processes and design of the systems have been
performed by computer simulation.

HOSOKAWA POWDER TECHNOLOGY FOUNDATION
Shoudai-Tajika 1-9, Hirakata, Osaka, 573-1132 Japan
Tel: + 81-72-867-1686 Fax: + 81-72-867-1658 E-mail: contact_zainq@hmc.hosokawa.com URL: www.kona.or.jp

PROCESS TECHNOLOGIES FOR TOMORROW

ABSTRACT:COMPUTERIZATION OF POWDER PROCESSING SYSTEMS
Steffen Sander, Gerhard Kiederle:
HOSOKAWA ALPINE AG, Augsburg, Germany
Computers have become ubiquitous in all aspects ofour lives. We are able to access our e-mail accountwherever we are. Household appliances and evencomplex industrial systems can be controlled by smart
phones. The next steps will be the self-organizationof manufacturing processes by means of machine-tomachine communication and the “web of things”– inGermany known as “Industry 4.0”. But how can one
turn this tremendous development in computing
applications to account in powder processing?
The presentation introduces HOSOKAWA ALPINE’s
recent developments in control systems and related
issues. It will focus on the online measurement ofparticle size distributions and how this tool can beused for an adaptive control of process or machineparameters. We will also highlight the potential oftele-service applications and a newly developed tool
which enables condition-based maintenance for
reducing downtime. There are many ways in which thecomputerization of powder processing systems canhelp to obtain products within the optimum quality
range and with increased overall process efficiency.

HOSOKAWA POWDER TECHNOLOGY FOUNDATION
Shoudai-Tajika 1-9, Hirakata, Osaka, 573-1132 Japan
Tel: + 81-72-867-1686 Fax: + 81-72-867-1658 E-mail: contact_zainq@hmc.hosokawa.com URL: www.kona.or.jp

PROCESS TECHNOLOGIES FOR TOMORROWPOWTECH + TechnoPharm 2014
We invite you to pay the POWTECH and TechnoPharm
trade fairs (30.09. – 02.10.2014) a visit. In combination
with the Hosokawa European Powder Technology
Symposium 2014, we will organise a coach trip on
Tuesday, the 30th September, between Augsburg andNuremberg to enable you to visit the trade fairs.
The POWTECH is the world-leading trade fair forprocessing, analysis and handling of powders andbulk solids. Some 700 companies from more than 20countries show their product spectrum. The Hosokawa
Micron Group is the exhibitor with the largest stand(450 m² floor space) at the POWTECH.

HOSOKAWA MICRON Group booth at the POWTECH 2013

TechnoPharm 2014 - international trade fair for life
science process technologies. Some 300 companies
from more than 20 countries show their productspectrum in pharma, food and cosmetics.
The POWTECH and TechnoPharm trade fairs both takeplace at the same time and the same location at theExhibition Centre Nuremberg.
Kindly make use of the appended registration form toregister for the symposium and the trip to POWTECH +TechnoPharm. Please send the form back to us by the
15th August 2014.

We will be pleased to answer any questions you may
have on the symposium and the POWTECH 2014:
HOSOKAWA ALPINE Aktiengesellschaft,Marketing Department (ZVF)
E-mail: marketing@alpine.hosokawa.com,
Tel:+49 (0) 821 5906 -358

Nuremberg, exhibition centre

Plan POWTECH + TechnoPharmHOSOKAWA POWDER TECHNOLOGY FOUNDATION
Shoudai-Tajika 1-9, Hirakata, Osaka, 573-1132 Japan
Tel: + 81-72-867-1686 Fax: + 81-72-867-1658 E-mail: contact_zainq@hmc.hosokawa.com URL: www.kona.or.jp

PROCESS TECHNOLOGIES FOR TOMORROW
directions to:
HOSOKAWA ALPINE AktiengesellschaftPeter-Dörfler-Str. 13-25
86199 Augsburg
Deutschland

EUROPEAN POWDER TECHNOLOGY SYMPOSIUM 2014
GETTING TO USHOSOKAWA ALPINE AktiengesellschaftPeter-Dörfler-Str. 13-25
86199 Augsburg
www.hosokawa-alpine.com
Tel:+ 49 821 5906-0
Fax:+ 49 821 5906-101
E-mail: mail@alpine.hosokawa.com

www.alpinehosokawa.com
Tel.:+49 821 5906-0
Fax.: +49 821 5906-101
E-Mail: mail@alpine.hosokawa.com

Main entrance,Gateway,Visitor parking area

Journey by car: from the north, east and west
on the A8 motorway
Journey by car: From the north, east andwest on the autobahn A8 (Munich –(Munich – Stuttgart):
Stuttgart):

 leave the A8 at the exit Augsburg-West to

B17follow
towards Augsburg,››leave the A8 at the exit Augsburg-West theandthe B17 towards

 after 10 km exit B17 at the exit Göggingen

Augsburg,Ost (alte Universität, Kongresshalle, Zoll /TÜV, Eichleitnerstraße) and turn left towards››after 10 km leave the B17 at the exit Göggingen
town centre, Ost (alte Universität,
m, atthetowards
set of first traffic
light, turnKongresshalle, Zoll / TÜV, Eichleitnerstraße) afterand500
turnleftthe town
left into Peter-Dörfler-Straße,centre,
after 300 m you will reach the main entrance ofHosokawa Alpine on the right››after 500 m, at the first set of traffic lights, turn left into Peter-DörflerStrasse,
drive for another 300 m and you will reach the main entrance of Hosokawa
Alpine on the right.