1 October 2018, London

9th Joint CSJ RSC Symposium:
Designing Molecular Function
at the Nano-Scale: Catalysis,
Materials and Supramolecular
ChemistryBook of
Abstracts
Registered charity number: 207890

Join the world’s
leading chemistrycommunity
The Royal Society of Chemistry
is the UK’s professional body forchemical scientists. We advanceexcellence in the chemical
sciences by supporting andrepresenting our members.
As a member we can help you:Plan and manage your career –with specialist advice, events anddevelopment opportunities
Tap into a global network – that offers
endless opportunities to promote and shareyour work, ideas and expertise
Be the first to know – about the latest
innovations and research in your field
Find your place in our community
Whatever your career level, there’s amembership option to suit you. When you
advance, you can change your category tomatch.

Join uswww.rsc.org/join

Registered charity number: 207890

Welcome address from the Royal Society of Chemistry
Dear Colleagues
It is my pleasure as Past-President of the Royal Society of Chemistry to welcome you to the 9th Joint CSJ RSC Symposiumon Designing Molecular Function at the Nano-Scale: Catalysis, Materials and Supramolecular Chemistry. A particularly warm
welcome to Professor Maki Kawai, President of the Chemical Society of Japan, and our Japanese speakers, all of whom havemade the long journey to the UK to be with us today.
The Royal Society of Chemistry has worked closely with the Chemical Society of Japan for a number of years to supportscientific collaboration and exchange between our two countries. In 2010 we formalised our relationship by signing aninternational cooperation agreement, which we renewed in 2015. This symposium is the latest in a series of successful joint
symposia that we have organised as part of this relationship. Five years ago, in 2014, I had the pleasure of addressing the
5th Joint CSJ RSC Symposium on Supramolecular Chemistry, an area not dissimilar to that of today’s symposium. I am
especially looking forward to hearing from our invited speakers on the latest advances in the fields of catalysis, materials andsupramolecular chemistry, and how these areas can be applied to design molecular function at the nano-scale.
I would like to thank the Chemical Society of Japan, particularly its President Professor Maki Kawai, Executive Director
Professor Mitsuo Sawamoto and International Relations Officer Ms Emiko Sakurada for their contribution to today’s event. My
thanks also go to Professor Jonathan Clayden and Professor Seiji Shirakawa for assembling such an impressive programme
representing some of the latest Japanese and UK research in this area of chemistry – thank you to each of the speakers and all
the participants for their contributions to this symposium. Finally I would like to thank the UK research groups who have kindly
arranged for some of our Japanese guests to visit their institutions during their time in the UK. Chemistry of course is, and must
always remain, collaborative and international, and events such as this give participants the opportunity to exchange ideas,
forge new friendships and embark on joint collaborations. I hope that today offers yet more opportunities for researchers fromthe UK and Japan to collaborate on this important topic.
Once again a very warm welcome to what promises to be an exciting scientific event. I wish you all an informative, productive
and enjoyable day.

Professor Lesley Yellowlees CBE, FRSE, HonFRSC
Past-President
Royal Society of ChemistryWelcome address from the Chemical Society of Japan
Dear Colleagues
Welcome to the 9th Joint CSJ RSC Symposium on Designing Molecular Function at the Nano-Scale: Catalysis, Materials andSupramolecular Chemistry. It is my pleasure as President of the Chemical Society of Japan to be with you today.
The Chemical Society of Japan (CSJ) and Royal Society of Chemistry (RSC) have collaborated on many successful joint
activities. Our interdisciplinary symposia offer a unique platform by bringing together scientists from different disciplines in Japanand the UK to share ideas and experiences.
Supramolecular chemistry has been and continues to be an area of particular focus for us in creating new and interesting
functional materials. In 2014 our two societies organized a joint symposium on supramolecular chemistry. In today’s symposium
we will hear how the fields of catalysis, materials and supramolecular chemistry can be applied to the areas of molecular spaceand design and new materials function.
Functional space is an important material component for molecular recognition and catalysis. A series of zeolites of differing
pore sizes ranging from the sub-nanometer to micron-meter scale can be used for a wide range of applications. Using a
supramolecular chemistry approach to synthesize homogeneous and precisely designed materials has the potential to enable
the known pore function of materials to functionalize each site of the pore with a view to producing new types of control
materials.
I would like to thank Professor Seiji Shirakawa, Professor Yoshinori Takashima and Professor Jonathan Clayden for suggesting
and refining the topic of the symposium, and for inviting so many excellent speakers to present their work to us today. I believe
this opportunity to sit together at the same table will provide a meaningful chance for sustainable collaboration between our two
countries.

Professor Maki Kawai
President
Chemical Society of Japan

Programme
Time

Event

09:30

Registration and coffee

10:15

Welcome remarks
Professor Lesley Yellowlees
Past-President, Royal Society of Chemistry
Professor Maki Kawai
President, Chemical Society of Japan

10:30

Design of organo-sulfur catalysts
Seiji Shirakawa

10:55

Asymmetry from the mechanical bond: Synthesis andapplications of “mechanically” chiral molecules
Steve Goldup

11:20

Coffee break

11:35

Development of chirality-switchable functional materials basedon the solvent-dependent inversion of the main-chain helicalchirality
Yuuya Nagata

12:00

Synthetic mimicry of biological communication devices
Jonathan Clayden

12:25

Exploring new concept for the use of sulfur in the molecular
design of functional Pi-electron materials
Aiko Fukazawa

12:50

Lunch and poster session

14:15

Pillar-shaped macrocyclic compounds “pillar[n]arenes”:
From simple molecular receptors to bulk supramolecularassemblies
Tomoki Ogoshi

14:40

Functional structures via subcomponent self-assembly
Jonathan Nitschke

15:05

Catalytic function dictated by the B3NO2 ring system
Naoya Kumagai

15:30

Coffee break

15:45

C-H functionalisations: Palladium, gold, light, dark?
Ai-Lan Lee

16:10

Supramolecular polymeric materials functionalized by hostguest interactions and its stimuli-responsive properties
Yoshinori Takashima

16:35

Template-directed synthesis and electronic delocalizationin molecular nanocages and nanorings
Harry Anderson

17:00

Presentation of poster prizes

17:10

Closing remarks
Mr Paul Lewis
Deputy CEO, Royal Society of Chemistry

17:30

Networking reception

Chair

Dr Robert Parker
CEO, Royal Society ofChemistry

Jonathan Clayden

Seiji Shirakawa

Steve Goldup

Aiko Fukazawa

Ai-Lan Lee

Biographical notes of invited speakers
Harry Anderson
University of Oxford, UK
Email: harry.anderson@chem.ox.ac.uk
Harry Anderson obtained his BA in chemistry from the University of Oxford under John
M. Brown and his PhD in chemistry from the University of Cambridge under Jeremy K.
M. Sanders. He held postdoctoral research fellowships at Magdalene College Cambridge(1990-1993) followed by ETH- Zürich (1993-1994), before moving to Oxford in 1994
to become a lecturer in organic chemistry. He was a Tutorial Fellow at Keble College
from 1994-2013 and has been a Professorial Fellow since October 2013. He has
published more than 280 research articles in peer-reviewed journals, and is interested
in molecules with extended π-systems and supramolecular self-assembly. He hasreceived the 2001 Corday-Morgan Award (Royal Society of Chemistry), 2003 Bob Hay
Lecturer (Royal Society of Chemistry, Macrocyclic Chemistry), 2003 Award for Materials
Chemistry (Royal Society of Chemistry), 2006 Award for Supramolecular Chemistry(Royal Society of Chemistry), 2012 Tilden Prize (Royal Society of Chemistry), 2013 ERC
Advanced Investigator Award, and the 2017 Izatt-Christensen Award for Macrocyclic andSupramolecular Chemistry. He has also held a number of lectureships throughout his
career, including the 2013 Alexander Todd – Hans Krebs Lectureship (RSC/GDCh). He isa fellow of the Royal Society (elected 2013) and the Royal Society of Chemistry (elected2003), an Honorary Member of the Israel Chemical Society (2014) and a member of theAmerican Chemical Society.

Jonathan Clayden
University of Bristol, UK
Email: j.clayden@bristol.ac.uk
Jonathan Clayden was born in Uganda in 1968, grew up in the county of Essex, and wasan undergraduate at Churchill College, Cambridge. In 1992 he completed a PhD at the
University of Cambridge with Dr Stuart Warren. After postdoctoral work with Professor
Marc Julia at the École Normale Supérieure in Paris, he was appointed as lecturer at the
University of Manchester in 1994. In 2001 he was promoted to professor, and in 2015 hemoved to the University of Bristol. He has published 270 papers, and his research interests
encompass areas of synthesis and stereochemistry where conformation has a role to play:
dynamic foldamers, atropisomerism, organolithium chemistry, conformationally-induced
reactivity and long-range stereochemical effects. He pioneered the field of dynamic foldamer
chemistry, using molecular conformational features to devise synthetic mimics of biologicalcommunication devices, including an artificial membrane-bound receptor and a mimic of
the vision protein rhodopsin, and he has established the feasibility of stereochemical control
over nanometre distances. His work on conformationally induced reactivity has led to new
dearomatisation, arylation, and ring expansion chemistry applicable to the synthesis ofchallenging targets of actual and potential biological activity. He is a co-author of the widelyused textbook “Organic Chemistry” published by OUP, and his book “Organolithiums:
Selectivity for Synthesis” was published by Pergamon in 2002. He has received the Royal
Society of Chemistry’s Meldola (1997) and Corday Morgan (2003) medals, Stereochemistry
Prize (2005), Hickinbottom Fellowship (2006), Merck Prize (2011) and Tilden Award(2018), and the Novartis Young European Investigator Award (2004). He has held an ERC
Advanced Grant and has been awarded senior research fellowships from the Leverhulme
Trust and the Royal Society.

Aiko Fukazawa
Nagoya University, Japan
Email: aiko@chem.nagoya-u.ac.jp
Aiko Fukazawa studied chemistry at Kyoto University where she obtained her B. Eng.
degree and M. Eng. degree in 2002 and 2004, respectively, under the supervision ofProfessor Kohei Tamao. On the way to pursing her doctorate at the same university,
she moved to Professor Shigehiro Yamaguchi’s research group in Graduate School of
Science at Nagoya University as an assistant professor in 2006, received her Dr. Sci. from
Nagoya University in 2008, and promoted to an associate professor in August 2013. She
also spent two months to work with Professor Warren E. Piers at University of Calgary
as a visiting scholar in 2011. Since April 2013, she has been concurrently serving as
a collaborating investigator in the Institute of Transformative Bio-Molecules in Nagoya
University. Based on her achievements in the field of main-group chemistry, she received
several awards including Inoue Research Aid for Young Scientists (2009), Asian Core
Program Lectureship Award to Taiwan and Singapore (2010), The Chemical Societyof Japan Award for Distinguished Young Chemists (2014), and Nozoe Young Scientist
Award (2017). Her research interests include the development of novel functional organic
materials on the basis of physical organic chemistry and main group chemistry.

Steve Goldup
University of Southampton, UK
Email: s.goldup@soton.ac.uk
I studied at the University of Oxford (MChem, Prof. Sir Jack Baldwin) and Imperial College(PhD, Prof. Tony Barrett) where my research focused on natural product synthesis,
before moving to Edinburgh (PDRA, Prof. David Leigh) to apply my synthetic skills tointerlocked molecules and molecular machines. In 2008 I took up my first independent
research position at Queen Mary, University of London, first as a Leverhulme Trust Early
Career Fellow and then as a Royal Society Research Fellow and Senior Lecturer. In
2014 I moved to the University of Southampton where I am now Professor of Chemistry.
I work with an outstanding group of young scientists demonstrating new applicationsof interlocked molecules in a range of areas including catalysis, materials, sensing
and chemical biology. We are particularly interested in the applications of new forms ofstereochemistry associated with the mechanical bond.

Naoya Kumagai
Institute of Microbial Chemistry, Japan
Email: nkumagai@bikaken.or.jp
Naoya Kumagai was born in 1978 and raised in Ibaraki (Japan). He obtained hisbachelor’s (2000), Master’s (2002), PhD degrees (2005) in pharmaceutical sciencesat The University of Tokyo (Japan), under the supervision of Professor Masakatsu
Shibasaki. He received JSPS research fellowships for young scientists (2002−5).
He pursued postdoctoral studies in the laboratory of Professor Stuart L. Schreiber at
Harvard University (USA) in 2005-6. He moved back to Professor Shibasaki’s group at
The University of Tokyo as an assistant professor in 2006. He moved to the Instituteof Microbial Chemistry (Tokyo, Japan) together with Prof. Shibasaki in 2010 and iscurrently a Chief Researcher. He is a recipient of the Pharmaceutical Society of Japan
Award for Young Scientists (2010), Thieme Chemistry Journals Award (2013), Young
Scientists’Prize, The commendation for Science and Technology by the Minister of
Education, Culture, Sports, Science and Technology (2013), and Mitsui Chemicals
Catalysis Science Award of Encouragement (2014), and Merck-Banyu Lectureship Award(2017). His research interests include the development of new methodologies in catalysis,design & synthesis of exotic molecular architectures.

Ai-Lan Lee
Herriot-Watt University, UK
Email: A.Lee@hw.ac.uk
Ai-Lan was born in Malaysia and obtained her MSci (Hons) (2000) and PhD (2004) from
University of Cambridge, working under the supervision of Prof. Steven V. Ley. She wassubsequently awarded a Lindemann Trust Fellowship (2004-2005) to work at Boston
College with Prof. Amir Hoveyda on alkene metathesis. In 2006, Ai-Lan was appointed
as a fixed-term Lecturer at the University of Edinburgh, carrying out research with Prof.
David Leigh on rotaxane synthesis. She started as a Lecturer at Heriot-Watt University
in 2007 and is currently Associate Professor and Reader. Her research interests include
developing new gold-, palladium- and dual photoredox-catalysed reactions.

Yuuya Nagata
Kyoto University, Japan
Email: nagata@sbchem.kyoto-u.ac.jp
Yuuya Nagata is an Assistant Professor at Kyoto University. He studied polymer chemistryat Kyoto University, obtaining his PhD under the supervision of Prof. Yoshiki Chujo in
2008. Later, he joined Prof. Michinori Suginome’s group at Kyoto University. His interest is
focused on the science of helical polymers to figure out the nature of chirality. In particular,
he is interested in the synthesis and the screw-sense control of poly(quinoxaline-2,3-diyl)s,
which exhibit various molecular functions including asymmetric catalysis and generation of
circular polarized light. He is also interested in the use of various techniques to investigate
helical polymers, including neutron beam scattering, synchrotron X-ray scattering anddiffractions, high-pressure circular dichroism measurements, and large-scale theoretical
calculations. He has been awarded several prizes, including the Special Lecturer for
Young Chemists (the Chemical Society of Japan, 2015), the Young Scientist Presentation
Award (the Society of Polymer Science, Japan, Kansai Regional Chapter, 2015), and the
CSJ Award for Young Chemists (the Chemical Society of Japan, 2017).

Jonathan Nitschke
University of Cambridge
Email: jrn34@cam.ac.uk
Jonathan Nitschke received his bachelor’s degree from Williams College (USA) in
1995 and his doctorate from the University of California, Berkeley in 2001 under thesupervision of T. Don Tilley. He then undertook postdoctoral studies with Jean-Marie
Lehn in Strasbourg under the auspices of a US NSF fellowship, and in 2003 he started
his independent research career as a Maître-assistant (fixed-term independent PI) in the
Organic Chemistry Department of the University of Geneva. In 2007 he was appointed
University Lecturer at Cambridge, where he now holds a Professorship. His research
program investigates the self-assembly of complex, functional structures from simple
molecular precursors and metal ions.

Tomoki Ogoshi
Kanazawa University, Japan
Email: ogoshi@se.kanazawa-u.ac.jp
Tomoki Ogoshi received his B.S. (2000), M.S. (2002), and Ph.D. degrees (2005) from
Kyoto University under the supervision of Prof. Yoshiki Chujo. He was a JSPS postdoctoral
research fellow (2005−2006) in the Graduate School of Science at Osaka University in thegroup of Prof. Akira Harada. In 2006, he moved to the Graduate School of Natural Scienceand Technology at Kanazawa University as an assistant professor (2006-2010). He was an
associate professor (2010-2015) and was promoted to a professor at the same university
at 2015. He works also as JST-PRESTO Researcher: PRESTO program “Hyper-nanospace design toward innovative functionality” from Oct. 2013 under the research supervisorof Prof. Kazuyuki Kuroda (Waseda University). He was a visiting professor at Universityof Amsterdam (co-worker: Albert M. Brouwer, May 2017-Jan. 2018). He has received
HGCS Japan Award Excellence 2010 (2011), The Chemical Society of Japan Award forYoung Chemists (2012), The Cram Lehn Pedersen Prize in Supramolecular Chemistry;
Royal Society of Chemistry (2013), The Commendation for Science and Technology by the
Minister of Education, Culture, Sports, Science and Technology (2014), Nozoe Memorial
Award for Young Organic Chemists (2016), Banyu Chemist Award 2016 (2016) and
Lectureship Award MBLA 2016 (2017). His research interests include organic synthesis, andsupramolecular and hybrid materials.

Seiji Shirakawa
Nagasaki University, Japan
Email: seijishirakawa@nagasaki-u.ac.jp
Seiji Shirakawa was born in 1974 in Ehime, Japan. He graduated from Nihon University(1997) and received his Ph.D. (2004) from Kyoto University under the supervision ofProfessor Keiji Maruoka. He worked with Professor James L. Leighton at Columbia
University (2004–2005) and Professor Shū Kobayashi at University of Tokyo (2005–2007) as a postdoctoral fellow. He was appointed as an assistant professor at Nihon
University in 2007, and moved to Kyoto University as an associate professor (2009). He
is currently an associate professor in Nagasaki University since 2014. He has received
The Commendation for Science and Technology by the Minister of Education, Culture,
Sports, Science and Technology, The Young Scientists’ Prize (2013), Incentive Award in
Synthetic Organic Chemistry, Japan (2014), and Nagase Foundation Award (2015). His
research interests include supramolecular catalysis, onium salt catalysis, and organosulfur catalysis.

Yoshinori Takashima
Osaka University, Japan
Email: takasima@chem.sci.osaka-u.ac.jp
Yoshinori Takashima was born in 1974 in Osaka, Japan. He received his Ph.D. degreein 2002 from Osaka University, under the guidance of Prof. Akira Harada (Osaka Univ.),
focusing on the polymerization catalyst using group 4 transition metal catalyst. He wasselected as a Research Fellow of the Japan Society for the Promotion of Science (JSPS)in 1999–2002. During the winter of 2003, as a visiting fellow, he worked at Prof. Jeffrey
M. Stryker’s lab, Department of Chemistry, the Univ. of Alberta. In 2003, he obtained his
PhD in Polymer Science from Osaka Univ. Prior to joining the Graduate School of Scienceat Osaka Univ. in 2004 as an assistant prof. for Prof. Akira Harada, he served as a
postdoctoral research fellow from JSPS in the Division of Applied Chemistry, Osaka Univ.
for Professor Toshikazu Hirao. In 2011, he worked at Prof. Philip A. Gale’s lab, Departmentof Chemistry, the Univ. of Southampton as a visiting researcher. In 2016, he joined the
Graduate School of Science at Osaka Univ. as a lecturer. In 2018, he visited to Prof.
Nicolas Guiseppone of the Univ. of Strasbourg as a visiting professor. At the same year,
he joined Institute for Advanced Co-Creation Studies and the Graduate School of Scienceat Osaka Univ. as a professor. His research interests include supramolecular materials,
catalysts, molecular motors and devices.

Template-directed synthesis and electronic delocalization inmolecular nanocages and nanorings
Harry L. Anderson
Department of Chemistry, University of Oxford, Oxford OX1 3TA UK
harry.anderson@chem.ox.ac.uk
Large monodisperse π-conjugated nanostructures based on metalloporphyrins, with sizes similar to those ofproteins, are becoming increasingly accessible due to advances in template-directed synthesis. The propertiesof these systems are just starting to be understood. They are unique model systems for testing electronic
delocalization in molecular nanostructures.
This presentation will focus on the synthesis, aromaticity and electronic delocalization in large π-conjugatednanorings, nanotubes and nanoballs constructed from porphyrin units.2 The spectroscopy of the simple porphyrin
nanorings continues to generate surprises,3 while advances in template-directed synthesis are rapidly providing
access to new architectures, such as the 14-porphyrin nanoball shown below (Figure 1), which features two
orthogonal intersecting π-conjugated circuits.4 Results will also be presented on single-molecule charge-transport
through these systems.

Figure 1. Calculated structure of a π-conjugated nanoball consisting of 14 zinc porphyrin centers. (Hydrogen atoms andsolubilizing side groups not shown.)4

References
1. M. D. Peeks, T. D. W. Claridge, H. L. Anderson, Nature 2017, 541, 200.
2. P. Neuhaus, A. Cnossen, J. Q. Gong, L. M. Herz, H. L. Anderson, Angew. Chem. Int. Ed. 2015, 54, 7344.
3.	M. D. Peeks, C. E. Tait, P. Neuhaus, G. M. Fischer, M. Hoffmann, R. Haver, A. Cnossen, J. R. Harmer, C. R. Timmel,
H. L. Anderson, J. Am. Chem. Soc. 2017, 139, 10461.
4.	J. Cremers, R. Haver, M. Rickhaus, J. Q. Gong, L. Favereau, M. D. Peeks, T. D. W. Claridge, L. M. Herz, H. L. Anderson,
J. Am. Chem. Soc. 2018, 140, 5352.

Synthetic mimicry of biological communication devices
Jonathan Clayden
School of Chemistry, University of Bristol, Cantock’s Close, Bristol BS8 1TS, UK
j.clayden@bristol.ac.uk
Biology communicates information through cell membranes by means of conformationally switchable proteins, ofwhich the most important are the G-protein coupled receptors (GPCRs). This lecture will explore the design andsynthesis of artificial mimics of GPCRs, with the ultimate aim of controlling function in the interior of an artificial
vesicle. Prospects for future developments of molecular devices capable of encoding information in conformationand translating that information into chemical function will be assessed.
References
1.	F. G. A. Lister, B. A. F. Le Bailly, S. J. Webb, J. Clayden, Nature Chem. 2017, 9, 420-425;
2.	M. De Poli, W. Zawodny, O. Quinonero, M. Lorch, S. J. Webb and J. Clayden, Science 2016, 352, 575–580;
3.	B. A. F. Le Bailly, J. Clayden, Chem. Commun. 2016, 52, 4852–4863

Exploring new concept for the use of sulfur in the molecular designof functional Pi-electron materials
Aiko Fukazawa
Department of Chemistry, Graduate School of Science, Nagoya University, Japan
aiko@chem.nagoya-u.ac.jp
Incorporation of main-group elements into π-conjugated frameworks is one of the promising approaches for themodulation of electronic structures and thus their optical and/or electronic properties. However, this approach
often poses a challenge of compromise between unusual electronic structure and chemical stability of theresulting π-systems. In this regard, sulfur-containing π-conjugated systems are attractive class of materials
owing to their high stability and attractive electronic properties. Nevertheless, most of the molecular designfor thiophene- or TTF-based π-conjugated systems has focused on their electron-donating characters basedon the orbital interaction between sulfur lone pair electrons and π-systems. Our idea is to utilize these latentcharacteristics of sulfur for the molecular design of functional π-electron materials. In this presentation, I will
discuss our recent results, including 1) the utilization of the weak aromatic character of thiophenes for thestabilization and activation of highly reactive nonbenzenoid hydrocarbons,1 and 2) the development of novel
solubilizing groups for π-electron systems based on sulfur containing medium rings.2
References
1.	(a) Fukazawa, A.; Oshima, H.; Shiota, Y.; Takahashi, S.; Yoshizawa, K.; Yamaguchi, S. J. Am. Chem. Soc. 2013, 135, 1731.
(b) Fukazawa, A.; Oshima, H.; Shimizu, S.; Kobayashi, N.; Yamaguchi, S. J. Am. Chem. Soc. 2014, 136, 8738.
(c) Oshima, H.; Fukazawa, A.; Sasamori, T.; Yamaguchi, S. Angew. Chem. Int. Ed. 2015, 54, 7636.
(d) Oshima, H.; Fukazawa, A.; Yamaguchi, S. Angew. Chem. Int. Ed. 2017, 56, 3270.
2.	Fukazawa, A.; Toda, Y.; Hayakawa, M.; Sekioka, A.; Ishii, H.; Okamoto, T.; Takeya, J.; Yamaguchi, S. Chem. Eur. J.
2018, 24, 11503.

Asymmetry from the mechanical bond: Synthesis and applicationsof “mechanically” chiral molecules
Steve Goldup
University of Southampton, Southampton, SO17 1BJ, UK
s.goldup@soton.ac.uk
Interlocked molecules can display forms of stereochemistry that do not rely on classical covalent stereogenic
units.1 Our group have pioneered the use of “small” macrocycle2,3 mediated active template4 reactions in order
to allow the synthesis of challenging interlocked structures,5,6,7 for applications in sensing8 and catalysis.9 Here
we describe recent progress in the stereoselective active template synthesis of enantiopure mechanically planarchiral rotaxanes (a)10 and topologically chiral catenanes (b)11 for a range of applications.

References
1. E. M. G. Jamieson, F. Modicom, S. M. Goldup, Chem. Soc. Rev. 2018, DOI: 10.1039/C8CS00097B.
2. H. Lahlali, K. Jobe, M. Watkinson, S. M. Goldup, Angew. Chem., Int. Ed. 2011, 50, 4151.
3.	J. E. M. Lewis, R. J. Bordoli, M. Denis, C. J. Fletcher, M. Galli, E. A. Neal, E. M. Rochette, S. M. Goldup, Chem. Sci. 2016,
7, 3154.
4.	M. Denis, S. M. Goldup, Nature Rev. Chem. 2017, 0061.
5. E. A. Neal, S. M. Goldup, Chem. Sci. 2015, 2398.
6. E. A. Neal, S. M. Goldup, Angew. Chem. Int. Ed. 2016, 55, 12488.
7. J. E. M. Lewis, J. Winn, L. Cera, S. M. Goldup J. Am. Chem. Soc. 2016, 138, 16329.
8.	M. Denis, L. Qin, P. Turner, K. Jolliffe, S. M. Goldup, Angew. Chem. Int. Ed. 2018, 57, 5315; M. Denis, J. Pancholi, K. Jobe,
M. Watkinson, S. M. Goldup, Angew. Chem. Int. Ed. 2018, 57, 5310.
9.	M. Galli, J. E. M. Lewis, S. M. Goldup, Angew. Chem. Int. Ed. 2015, 54, 13545.
10. R. Bordolli, S. M. Goldup, J. Am. Chem. Soc. 2014, 136, 4817.
11. M. Denis, F. Modicom, J. E. M. Lewis, S. M. Goldup, submitted.

Catalytic function dictated by the B3NO2 ring system
Naoya Kumagai
Institute of Microbial Chemistry, Japannkumagai@bikaken.or.jp
The state-of-the-art chemical toolbox for the amide bond formation deploys a catalytic alternative to allow fordehydrative amidation avoiding the formation of reagent-derived waste, which is never fulfilled by the reagentdriven amidation. While more than two decades have passed since the first manifestation of the catalytic
amidation, catalytic protocols have not been widely adopted in practical synthesis due to limited catalytic activity
and substrate generality. In particular, embracing α-amino acids as substrates to catalytically forge amide bondsof peptides, a representative amide-rich chemical entity of significant biological interest, remains challenge tosynthetic chemists. The chemical synthesis of peptides is a research area of significant biological and practical
impact with high demand, and engineered and expensive coupling reagents are primarily utilized to couple
α-amino acid units for reliable conversion and stereochemical integrity. Herein we introduce an exotic heterocycle
DATB (1,3-dioxa-5-aza-2,4,6-triborinane, B3NO2 ring system), a multiboron catalyst amenable for dehydrative
direct amidation. DATB is capable of interconnecting a range of carboxylic acids and amines, including stericallydemanding substrates, sulfoximines, and all of the natural α-amino acids. Recent efforts on mechanistic study willbe also presented, illuminating the particular activation mode exerted by the peculiar B3NO2 ring system.

C-H functionalisations: Palladium, gold, light, dark?
Ai-Lan Lee
Institute of Chemical Sciences, Heriot-Watt University, Edinburgh EH14 4AS, UK
A.Lee@hw.ac.uk
This talk will cover 3 different types of C-H functionalisations developed within the Lee Group: using Pd-catalysis,dual gold and photoredox catalysis, and finally using no catalysis.
Palladium Catalysis: A direct Pd-catalyzed C-H functionalisation of benzoquinone (BQ) will be discussed, which
can be controlled to give either monosubstituted or disubstituted BQ, including the installation of two different
groups in a one-pot procedure.2 BQ can now be directly functionalized with aryls, heteroaromatics, cycloalkyls andcycloalkenes and, moreover, the process exploits environmentally benign water or acetone as solvents.
Gold/Photoredox Catalysis: The merging of photoredox catalysis with gold catalysis is a relatively new yet
vibrant field as it enables the access of Au(I)/Au(III) catalytic cycles,2 and thereby the ability of gold to catalyse
cross-couplings without the need for stoichiometric oxidants. Within this context, a mild and fully catalytic arylaryl cross coupling via gold-catalysed C-H activation has been achieved by merging gold and photoredox
catalysis.3 The procedure is free of stoichiometric oxidants and additives, which were previously required in goldcatalysed C-H activation reactions. One of the key benefits of gold-catalysed C-H activation is regioselectivity,
without the need for directing groups. Indeed, we show that exploiting dual gold and photoredox catalysis
confers regioselectivity via the crucial gold-catalysed C-H activation step, which is not present in the unselective
photocatalysis-only counterpart.

C-H Alkylations, Uncatalysed: Finally, our recent progress on developing metal, photocatalyst and light-free,late-stage C-H alkylation of heteroarenes and 1,4-quinones using carboxylic acids will be covered.
References
1. M. N. Hopkinson, A. Tlahuext-Aca, F. Glorius, Acc. Chem. Res. 2016, 49, 2261.
2.	S. E. Walker, J. A. Jordan-Hore, D. G. Johnson, S. A. Macgregor, A.-L. Lee, Angew. Chem. Int. Ed., 2014, 53, 13876.
3. V. Gauchot, D. R. Sutherland, A.-L. Lee, Chem. Sci., 2017, 8, 2885.

Development of chirality-switchable functional materials based on
the solvent-dependent inversion of the main-chain helical chirality
Yuuya Nagata
Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering,
Kyoto University, Japannagata@sbchem.kyoto-u.ac.jp
Increasing attention has focused on the screw-sense control of the polymer backbone for the development of
new chiral functional materials, including asymmetric catalysts and chiroptical materials. Recently, we found thatpoly(quinoxaline-2,3-diyl)s bearing chiral side chain adopts purely single-handed helical conformations, whose
helical chirality can be perfectly controlled by the solvents (the solvent-dependent helix inversion, Figure 1a).1–3
In this presentation, we present the development of new chirality-switchable functional materials based on thesolvent-dependent helix inversion of poly(quinoxaline-2,3-diyl)s (Figures 1b and 1c)4–7 along with the elucidation of
the mechanism of the helix inversion.8

Figure 1. (a) The solvent-dependent helix inversion of poly(quinoxaline-2,3-diyl)s and chirality-switchable (b) cholesteric and(c) circular polarized luminescent (CPL) materials.

References
1. Yamada, T.; Nagata, Y.; Suginome, M. Chem. Commun. 2010, 46, 4914–4916.
2.	Nagata, Y.; Yamada, T.; Adachi, T.; Akai, Y.; Yamamoto, T.; Suginome, M. J. Am. Chem. Soc. 2013, 135, 10104–10113.
3. Nagata, Y.; Nishikawa, T.; Suginome, M. J. Am. Chem. Soc. 2014, 136, 15901–15904.
4. Nagata, Y.; Takagi, K.; Suginome, M. J. Am. Chem. Soc. 2014, 136, 9858–9861.
5. Nagata, Y.; Uno, M.; Suginome, M. Angew. Chem. Int. Ed. 2016, 55, 7126–7130.
6. Nagata, Y.; Nishikawa, T.; Suginome, M. Chem. Commun. 2014, 50, 9951–9953.
7. Nagata, Y.; Nishikawa, T.; Suginome, M. ACS Macro. Lett. 2017, 6, 431–435.
8.	Nagata, Y.; Nishikawa, T.; Suginome, M.; Sato, S.; Sugiyama, M.; Porcar, L.; Martel, A.; Inoue, R.; Sato, N.
J. Am. Chem. Soc. 2018, 140, 2722–2726.

Functional Structures via Subcomponent Self-Assembly

Functional structures
via subcomponent
self-assembly
JonathanR. Nitschke
JonathanUniversity
R. Nitschke
Department of Chemistry,of Cambridge, UK
Department of Chemistry, University of Cambridge, UK
jrn34@cam.ac.uk
jrn34@cam.ac.uk

The materials that we depend on rely upon ever-increasing structural complexity for their function.
The materials that we depend on rely upon ever-increasing structural complexity for their function. The use ofThe
use of chemical self-assembly as a synthetic technique can simplify materials preparation bychemical self-assembly as a synthetic technique can simplify materials preparation by shifting intellectual effort
shifting
intellectual
effort awayfrom designingand towards
designof chemical
away fromdesigning molecules,
and towards
the design molecules,of chemical systems
that arethe
capableof self-assembling
systemsthatarecapableofself-assembling
in
such
a
way
as
to
expressdesiredmaterials
properties
in such a way as to express desired materials properties and functions. Below are shown the subcomponent
andfunctions.
Below
are
shown
the
subcomponent
precursors
andstructures
of
three
of
products
precursors and structures of three of products that can form functional constituents of these systems (Figure that1).
can form functional constituents of these systems (Figure 1).
NH2

H2 N

6

N

Ni

-

O

N
N

O3S

6 H2N

24 N

N

NH2

12 O
N

SO 3-

P

4 FeIISO4 H2O
H2N

8 FeII H2O

P

2

1
II

P

P

NH2

1

II

2

3
I

3

Figure 1. Fe 8 cubic
cage 1, Fe 4 tetrahedral
2, and electroluminescentCu n double-helical polymer 3
Figure1. FeII8 cubic
cage 1,1 FeII4 cage
tetrahedral
cage 2,2 and electroluminescent
CuIn double-helical
Current challenges
involve inducing multiple structures to form in parallel,4 such that they may act in concert topolymer
33

achieve a catalytic goal,5 our techniques allow entry into the emerging field of systems chemistry.6 Functional
4 7
Current
involve
inducinginclude
multiplestructures toself-assembly
form in parallel,suchthey ofmay
actandthata series
cages
systemsthatchallenges
we have recently
developed
a fuel-controlled
process
589andtransitbetweenliquidphases.
thatcanphase-segregate
in concert to achieve a catalytic goal, our techniques allow entry into the emerging field of systems

chemistry.6 Functional systems that we have recently developed include a fuel-controlled selfReferences
assembly process7 and a series of cages that can phase-segregate8 and transit between liquid phases.9

1.	W. Meng, B. Breiner, K. Rissanen, J.D. Thoburn, J.K. Clegg, J.R. Nitschke, Angew. Chem. Int. Ed. 2011, 50, 3479.
2. References
P. Mal, B. Breiner, K. Rissanen, J.R. Nitschke, Science 2009, 324, 1697.
3. J.L. Greenfield, F.J. Rizzuto, I. Goldberga, J. Nitschke, Angew. Chem. Int. Ed. 2017, 56, 7541.
1.4.	
W.
Meng, B.R.A.
Breiner,
Rissanen,Thoburn,
J.K. Clegg,
J.R. Nitschke,
Chem.
Int. Ed.
2011,
A. Jiménez,Bilbeisi,K.T.K.
Ronson, J.D.
S. Zarra,
C. Woodhead,
J.R. Nitschke,
Angew.Angew.
Chem. Int.
Ed. 2014,
53, 4556.
3479.
5. 50,
A.G.
Salles, S. Zarra, R.M. Turner, J.R. Nitschke, J. Am. Chem. Soc. 2013, 135, 17052.
2.6. P.J.R.
Mal,
B. Breiner,
Rissanen,
J.R. Nitschke, Science 2009, 324, 1697.
Nitschke,
NatureK.
2009,462, 736.
C.S.Greenfield,
Wood, C. Browne,
D.M. Wood,
J.R. Nitschke,ACS Cent. Angew.
Sci. 2015,
1, 504.Int. Ed. 2017, 56, 7541.
3.7. J.L.
F.J. Rizzuto,
I. Goldberga,
J. Nitschke,
Chem.
A.B.
Grommet,J.L.Bilbeisi,
Bolliger, C.
Browne,J.R. Nitschke,
Chem. Int.J.R.
Ed. Nitschke,
2015, 54, 15100.
4.8. A.
Jiménez,
R.A.
T.K.
Ronson,S. Zarra,Angew.
C. Woodhead,
Angew. Chem. Int. Ed. 2014,
A.B.4556.
Grommet, J.R. Nitschke, J. Am. Chem. Soc 2017, 139, 2176; B.S. Pilgrim, D.A. Roberts, T.G. Lohr, T.K. Ronson,
9.	
53,
J.R. Nitschke,
9, 1276.
5. A.G.
Salles, S.Nature
Zarra,Chem.
R.M.2017,
Turner,J.R. Nitschke, J. Am. Chem. Soc. 2013, 135, 17052.

6. J.R. Nitschke, Nature 2009, 462, 736.
7. C.S. Wood, C. Browne, D.M. Wood, J.R. Nitschke, ACS Cent. Sci. 2015, 1, 504.
8. A.B. Grommet, J.L. Bolliger, C. Browne, J.R. Nitschke, Angew. Chem. Int. Ed. 2015, 54, 15100.
9. A.B. Grommet, J.R. Nitschke, J. Am. Chem. Soc 2017, 139, 2176; B.S. Pilgrim, D.A. Roberts, T.G. Lohr,
T.K. Ronson, J.R. Nitschke, Nature Chem. 2017, 9, 1276.

Pillar-shaped macrocyclic compounds “pillar[n]arenes”: Fromsimple molecular receptors to bulk supramolecular assemblies
Tomoki Ogoshi
Graduate School of Natural Science and Technology, Kanazawa University,
Kakuma-machi, Kanazawa 920-1192, Japan
ogoshi@se.kanazawa-u.ac.jp
Macrocyclic compounds play a major role in supramolecular chemistry because of their beautiful shape, nanoscale size and molecular recognition ability. Numerous supramolecular architectures have been constructed andstudied as new components of materials as well as entities related to biological structural formation and functions
using various macrocyclic hosts.
In 2008, we reported a new class of macrocyclic hosts named “pillar[n]arenes”.1,2 Linear 1,2-dichloroethaneand bulky chlorocyclohexane acted as template solvents for high-yield synthesis of pillar[5]- and pillar[6]arenes, respectively. They have unique symmetrical pillar structures due to their para-bridge linkage. We havesynthesized various topological and functional molecules based on functionality of pillar[n]arenes, and constructed
2D sheets and 3D vesicles based on geometric assemblies of their pentagonal and hexagonal structures.3

References
1.	Ogoshi, T.; Kanai, S.; Fujinami, S.; Yamagishi, T.; Nakamoto, Y. J. Am. Chem. Soc. 2008, 130, 5022–5023.
2.	Reviews and book: Ogoshi, T.; Yamagishi, T.; Nakamoto, Y. Chem. Rev. 2016, 116, 7937–8002;
Murray, J.; Kim, K.; Ogoshi, T.; Yao. W.; Gibb. B. C. Chem. Soc. Rev. 2017, 46, 2479–2496;
Kakuta, T.; Yamagishi, T.; Ogoshi, T. Chem. Commun. 2017, 53, 5250–5266;
	Ogoshi, T.; Yamagishi, T. Chem. Commun. 2014, 50, 4776–4787; Pillararenes, Ogoshi, T. Ed.; The Royal Society ofChemistry: Cambridge, 2016.
3.	Ogoshi, T.; Sueto, R.; Yoshikoshi, K.; Yasuhara, K.; Yamagishi, J. Am. Chem. Soc. 2016, 138, 8064–8067;
	Ogoshi, T.; Takashima, S.; Yamagishi, T. J. Am. Chem. Soc. 2015, 137, 10962–10964;
Ogoshi, T.; Yoshikoshi, K.; Sueto, R.; Nishihara, H.; Yamagishi, T. Angew. Chem. Int. Ed. 2015, 54, 6466–6469;
Ogoshi, T.; Shimada, Y.; Sakata, Y.; Akine, S.; Yamagishi, T. J. Am. Chem. Soc. 2017, 139, 5664–5667.;
Ogoshi, T.; Sueto, R.; Yoshikoshi, K.; Sakata, Y.; Akine, S.; Yamagishi T. Angew. Chem. Int. Ed. 2015, 54, 9849–9852.

Design of Organo-Sulfur Catalysts
Seiji Shirakawa
Department of Environmental Science, Graduate School of Fisheries and Environmental Sciences,organo-sulfur
catalysts
Nagasaki Design
University,of
1-14,
Bunkyo-machi, Nagasaki
852-8521, Japanseijishirakawa@nagasaki-u.ac.jp
Seiji Shirakawa
Department
Graduateof Fisheries
andandEnvironmental
Despite oftheEnvironmental
wide synthetic Science,
utility of onium
salt School
compounds
as reagentscatalysts, the
Sciences,
Nagasaki
University,
1-14,
Bunkyo-machi,
Nagasaki852-8521,
Japan
catalytic ability of tertiary sulfonium salts has not yet been demonstrated well in organic
synthesis. To
seijishirakawa@nagasaki-u.ac.jp
create new possibilities for sulfonium salts as catalysts, we focused on the hydrogen-bonding abilitiesof � hydrogen atoms on alkylsulfonium salts when we reported the use of newly-designed

Despite the wide synthetic utility of onium salt compounds as reagents and catalysts, the catalytic ability of tertiary
tetraalkylammonium salts as hydrogen-bonding
catalysts on the basis of the characteristic properties
sulfonium salts has not yet been
demonstrated well in organic synthesis. To create new possibilities for sulfonium
1
Based
on
the
designofthe tetraalkylammonium
we focused onofthe�
hydrogenatoms.
salts as catalysts, we focused on the hydrogen-bonding abilitiesof α hydrogen atomssalts,
on alkylsulfonium
salts
simpletrialkylsulfonium
salts 1. The
catalytic ability saltsof trialkylsulfonium
saltscatalysts
was superior
when
wecyclic
reported
the use of newly-designed
tetraalkylammonium
as hydrogen-bondingon the to1
Based on2 the design of the tetraalkylammonium
basis
of the characteristic
properties of the αsaltshydrogenatoms.reactions.
that ofrelated tetraalkylammonium
in organic
1
salts, we focused on simple cyclic trialkylsulfonium salts. The catalytic ability of trialkylsulfonium salts was2
have
successfully
demonstrated
chiralreactions.
tertiary sulfonium
salt catalysts cansuperior toWe
thatalsoof therelatedtetraalkylammonium
saltsthatin organic

promote asymmetric reactions. Binaphthyl-modified bifunctional sulfonium salts 2 were efficient

We also have successfully demonstrated that chiral tertiary sulfonium salt catalysts can promote asymmetric 3
catalysts Binaphthyl-modified
for the asymmetricbifunctional
conjugatesulfonium
additionssalts
underbase-freephase-transfer
conditions.
2
wereefficientneutral
catalysts
for the asymmetricconjugate
reactions.
3
As far asunder
couldbase-free
be ascertained,
this is the firstexample Asof fara highlyenantioselective
as could
be ascertained, reaction
this is thecatalyzed
first
additions
neutral phase-transfer
conditions.
examplea highly sulfonium
enantioselective
by chiraloftertiarysalts.reaction catalyzed by chiral tertiary sulfonium salts.
2chiral sulfide
have also
been synthesizedandutilized as
Based onBasedthe designof chiralsulfonium
salts,
on thedesignof chiralsulfonium
salts catalysts
2, chiral3 sulfide
catalysts
3 have alsobeeneffective
Lewis
base
catalysts.
synthesized and utilized as effective Lewis base catalysts.

References
References
1.	S. Shirakawa, S. Liu, S. Kaneko, Y. Kumatabara, A. Fukuda, Y. Omagari and K. Maruoka, Angew. Chem., Int. Ed., 2015, 54,
1. 15767–15770.
S. Shirakawa, S. Liu, S. Kaneko, Y. Kumatabara, A. Fukuda, Y. Omagari and K. Maruoka,
Chem.,
Int. Ed.,
2015, K.
54,Maruoka,
15767–15770.
2. S.Angew.
Kaneko, Y.
Kumatabara,
S. Shimizu,
S. Shirakawa, Chem. Commun., 2017, 53, 119–122.
2. S.S.Liu,Kaneko,
Y.and
Kumatabara,
Shimizu,
Shirakawa, Chem. Commun., 2017, 53,
3.
K. Maruoka
S. Shirakawa, S.
Angew.
Chem., K.
Int. Maruoka,
Ed., 2017, 56,S.4819–4823.

119–122.
3. S. Liu, K. Maruoka and S. Shirakawa, Angew. Chem., Int. Ed., 2017, 56, 4819–4823.

Supramolecular polymeric materials functionalized by host-guest interactions

Supramolecular polymericmaterials functionalizedby host-guest
and its stimuli-responsive
properties
interactions and its stimuli-responsive properties
Yoshinori Takashima
Yoshinori Takashima
Institute for Advanced Co-Creation Studies, Osaka University, Graduate School of Science,

Institute for Advanced Co-Creation
Studies,
OsakaOsaka,
University,
Graduate, Toyonaka,
560-0043
Japan School of Science,
Osaka University
Osaka University, Toyonaka, Osaka, 560-0043 Japan
takasima@chem.sci.osaka-u.ac.jp
takasima@chem.sci.osaka-u.ac.jp
Molecular recognition chemistry and supramolecular chemistry
have received
much attention,owing
to their andeffects on
Molecular
recognition
chemistry
catalyticsupramolecular
activity, molecularswitches,andmaterials.
Stimulichemistry have received much
responsive
supramolecularpolymers
isrelevant
notfor
attention, owing to their effects on catalyticonly
activity,
biological
functions
but
also
for
a
range
of
other
applications.
molecular switches, and materials. Stimuli-responsive
Our researchgroup haspolymers
employediscyclodextrinsassupramolecular
relevant not(CDs)
only forhost molecules.
this presentation,
would
like toofintroduce
biologicalInfunctions
but alsoIfora rangeother
our studies
to realize sol-gel
switching,self-healing,adhesion
applications.
Our researchgroup
has employed
control,cyclodextrins
and contraction-expansion
properties
throughthe(CDs) as host molecules. In thisformationof inclusionIcomplexesCDs (Fig.our1). studies topresentation,
would likewith
to introduce

realize sol-gel switching, self-healing, adhesion control,

Adhesionself-healing material:
First, adhesion
and andcontraction-expansion
properties
through thebetweenthehosthydrogel
with
βCD
and
guest
formation of inclusion complexes thewith
CDshydrogel(Fig. 1).
with an adamantyl (Ad) group was investigated. The βCD
Adhesionandself-healingmaterial:
First, adhesionhydrogelselectively
adheresto the Ad
guest hydrogel
without
betweenthehosthydrogel
with
�CD
and
the guest
mismatching (Fig. 2).

Figure 1. Supramolecular materials based on host-guest
interactions with cyclodextrins (CDs).

hydrogel with an adamantyl (Ad) group wasinvestigated.
The �CD
hydrogelselectively
adheres
Next, weprepared effective
self-healingmaterials
based
theAd
Adunits.
guestWhenhydrogelwithout
mismatching(Fig. 2).
on βCDtoand
two cut
surfaceswere brought
into contact, the two pieces adhered. The adhered materials
Next, we prepared effective self-healing materials
showed almost complete recovery of the initial material
based on �CD and Ad units. When two cut surfaces
Figure 2. Self-healing materials based on host-guest
strength. The recovery ratio of the rupture strength increased
were brought into contact, the two pieces adhered. The interactions.
with adhesive time. Interestingly, only cut surfaces showed aadhered materials showed almost complete recovery ofself-healing property, whereas uncut surfaces did not.
the initial material strength. The recovery ratio of the
rupture strength
increasedadhesivetime.
Photoresponsive
materials:
Two with
structural
approaches
Interestingly,
only
cut
surfaces
showedaself-healing
may realize supramolecular actuators through host–guest
property,
whereasuncut
surfacesdidnot.
interactions: a method with a linear main chain and one with aside chain
in the polymer structure(Fig.
3). structural
We have prepared
Photoresponsive
materials:
Twophoto responsive
actuators by integrating
approachessupramolecular
may realize supramolecularactuators
host–guest
interactions
on thepolymer side
chains (Fig.
throughhost–guest
interactions:a methodwith 3a).
a linear
Anothermain
supramolecularhydrogels[c2]
chain and one
with a containingside chain CD-basedin the polymer
daisy chainsas crosslinkers
contractand expand
through
structure(Fig. 3). We
have preparedphoto
responsive
supramolecular
integrating
host–guest
photoresponsive
sliding actuators
motions ofby
the[c2]daisy chain(Fig. 3b).

interactions on the polymer side chains (Fig. 3a).

References
Another supramolecular hydrogels containing CD-

based
as crosslinkers
contract
1.	Harada,
A.;[c2]daisy
Takashima,chainsY.; Nakahata,
M. Acc. Chem.
Res.and2014,
47, expand
2128. through photoresponsive sliding motions of the
Figure 3. Supramolecular actuators using CD
2.	Nakahata,
M.; Takashima,
Yamaguchi H.; Harada, A.,[c2]daisy
chain (Fig.Y.;3b).
Nat. Commun. 2011, 2, 511.
derivatives. The actuators show macroscopic
References
3.	Kakuta,
T,; Takashima, Y.; Nakahata, M.; Otsubo, M,; Yamaguchi,
contraction–expansion and flexing behaviors.
H.; Harada, A. Adv. Mater. 2013, 25, 2849-2853.
Harada,Y.;
A.;Hatanaka,
Takashima,
Nakahata,
M.al.
Acc.
Chem.
Res. 2014,4.	(a) T(1)akashima,
S.;Y.;
Harada,A. et.
Nat.
Commun.
2012,47,
3,2128.
1270.
(2)Nakahata,
M.;
Takashima,
Y.;
Yamaguchi
H.;
Harada,A.,
Nat.
Commun.
2011,
2, 511.
(b) Nakahata, M.; Takashima, Y.; Harada, A. et. al. Angew. Chem. Int. Ed. 2015,
54, 8984-8987.
(3) Kakuta,Y.;
T,;Harada,
Takashima,Y.;al.Nakahata,
M.;2016,
Otsubo,Yamaguchi, H.; Harada, A. Adv. Mater. 2013, 25, 2849-2853.
5. (a) Takashima,
A. et.
Nat. Chem.
8, M,;
625-632.
(4) (a) Takashima,Y.; A.
Hatanaka,S.; Harada, A. et.
al. Nat.
Commun. 2012, 3, 1270. (b) Nakahata, M.; Takashima, Y.;(b) Takashima,Y.; Harada,
et. al. Macromolecules
2018,
51, 4688–4693.
Harada,A.
et.
al.
Angew.
Chem.
Int.
Ed.
2015,
54,
8984-8987.
6. Nakahata, M.; Takashima, H.; Harada, A. et. al. Chem. 2016, 1, 766-775.

NotesNotesNotesNotesNotesCM-0

Up-to-date andauthoritative books
from the Royal
Society of Chemistry

Specialist Periodical Reports

Energy & Environment Series

Nanoscience

X-Ray Free
Electron Lasers

Volume 4

Applications in Materials, Chemistry and Biology
Edited by P. John Thomas
and Neerish Revaprasadu

Edited by Uwe Bergmann, Vittal K. Yachandra
and Junko Yano

Chemical Biology

Issues in Toxicology

New Developments in NMR

Mass Spectrometry in
Chemical Biology

Nanotoxicology

Cross-relaxation and
Cross-correlation
Parameters in NMR

Experimental and Computational Perspectives

Evolving Applications
Edited by Norberto Peporine Lopes
and Ricardo Roberto da Silva

Edited by Alok Dhawan, Diana Anderson
and Rishi Shanker

Molecular Approaches
Bernard Ancian, Kavita Dorai and Fabien Ferrage
Edited by Daniel Canet

off for Royal Societyof Chemistry members
Shop online at
rsc.li/books
Registered charity number: 207890

CM-006-17_ Advert-New Books_210x275mm_updated aug 2017.indd 1

09/08/2017 15:14:56

Make themost of ourpublications
As one of the world’s leading academic publishers, we
produce over 40 peer-reviewed journals,
two magazines and have over 1,500 books covering
everything from medicinal chemistry to nanoscience.
• The average impact factor across our journal
portfolio has increased year on year, to 6.322*• 80% of our journals now have an Impact Factor
above 3*
With content valued by the global scientificcommunity, access is a highlight for our members.
As a professional member you get free access to:• One or more online journals of your choice• Free downloads – choose journal or eBook chapters• Additionally, for just £50 a year (excluding VAT)
you can subscribe to any of our other journals online

Find out more about membershipwww.rsc.org/join* 2017 Journal Citation Reports based on 2016 Web of Science data.
© Clarivate Analytics, 2017.

Royal Society of Chemistrywww.rsc.org
Registered charity number: 207890© Royal Society of Chemistry 2018

Thomas Graham House
Science Park, Milton Road
Cambridge, CB4 0WF, UK
Tel: +44 (0)1223 420066

Burlington House
Piccadilly, London
W1J 0BA, UK
Tel: +44 (0)20 7437 8656

International offices
São Paulo, Brazil
Beijing, China
Shanghai, China

Bangalore, India
Tokyo, Japan
Philadelphia, USA