Profile
Hiroshi Yamada, MD, PhD
Professor,
Department of Drug Evaluation & Informatics, School of Pharmaceutical Sciences,
University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka 422-8526, Japan
Phone: +81-54-264-5762; Fax: +81-54-264-5762
E-mail: hyamada@u-shizuoka-ken.ac.jp
Board Certifications:
Fellow of the American College of Internal Medicine (FACP)
Fellow of the Japanese Society of Internal Medicine
Fellow of the Japanese Society of Neurology
Fellow of the Japanese Society of Clinical Pharmacology
Previous Professional positions:1981 Apr. - 1983 Mar. Resident, Shizuoka General Hospital
1983 Apr. - 1986 Mar. Clinical fellow, Yaizu General Hospital
1986 Apr. - 1990 Mar. President, Ogasa Medical Center
1990 Apr. - 1994 Mar. Clinical fellow, Department of Neurology, Jichi Medical School
1994 Apr. - 1997 Mar. Assistant Professor of Neurology, Jichi Medical School
1997 Apr. - 2001 Aug. Director, Department of General Internal Medicine, Seirei
Hamamatsu General Hospital
2001 Sep. – 2005 Mar. Associate Professor of General Clinical Research Center,
Hamamatsu University, School of Medicine
2005 Sep. – present. Professor, Department of Drug Evaluation & Informatics,
School of Pharmaceutical Sciences, University of Shizuoka,
Academic Research:
1994 Jul - 1996 Jun. Visiting Research Fellow of Clinical Pharmacology, Karolinska
Institute, Huddinge University Hospital, Sweden
Research Interests:
1. Analysis and evaluation of the effectiveness and safety of health foods or
Pharmaceutical drugs.
2. Clinical application of electric monitoring device for measuring medication
adherence.
3. Methodology on the analysis and evaluation of clinical researches.
Bibliography:
1. Yoshikawa T, Yamada H, Matsuda K, Niino H, Sagesaka YM. Kakuda T,Toyoizumi K, Matsumoto K, Kosuge K, Uchida S, Onoue S, Yamada S, Umegaki
K. Effects of short-term consumption of a large amount of tea catechins on
chromosomal damage, oxidative stress markers, serum lipid, folic acid, and total
homocysteine levels: a randomized, double-blind, controlled study. Jpn J Clin
Pharmacol Ther 43:9-16. 2012.
2. Park M, Yamada H, Matsushita K, Kaji S, Goto T, Okada Y, Kosuge K, Kitagawa

1T. Green tea consumption is inversely associated with the incidence of influenza
infection among schoolchildren in a tea plantation area of Japan. J Nutr 141:
1862-1870, 2011.
3. Matsumoto K, Yamada H, Takuma N, Niino H, Sagesaka YM. Effects of green
tea catechins and theanine on preventing influenza infection among healthcare
workers: A randomized controlled trial. BMC Complement Altern Med 11:15,2011.
4. Yamada H, Watanabe H. Tea polyphenols in preventing cardiovascular diseases.
Cardiovasc Res 73:439-440, 2007.
5. Yamada H, Daimon T, Matsuda K, Yoshida M, Takuma N, Hara Y. A randomized
controlled study on the effects of gargling with tea catechin extracts on theprevention of influenza infection in healthy adults. Jpn J Clin Pharmacol Ther
38:323-330. 2007.
6. Daimon T, Yamada H, Goto M. Assessing nonlinearity in compartment models
via the relative curvature measure. J Pharmacokinet Phar, 34:207-227, 2007.
7. Uchida S, Yamada H, Dong LX, Maruyama S, Ohmori Y, Oki T, Watanabe H,Umegaki K, Ohashi K, Yamada S. Effects of Ginkgo biloba extract onpharmacokinetics and pharmacodynamics of tolbutamide and midazolam in
healthy volunteers. J Clin Pharmacol 46:1290-1298, 2006.
8. Yamada H, Tateishi M, Harada K, Ohashi T, Shimizu T, Atsumi T, Komagata Y,Iijima H, Komiyama K, Watanabe H, Hara Y, Ohashi K. A randomized clinicalstudy of tea catechin inhalation effects on methicillin-resistant Staphylococcus
aureus in disabled elderly patients. J Am Med Dir Assoc 7:79-83, 2006.
9. Yamada H, Sesoko S, Daimon T, Nakashima M. Application of a newly designed
electronic monitoring device for press through packaging sheets in a clinical trial.
Brit J Clin Pharmacol 61:238-239, 2006.
10. Yamada H, Takuma N, Daimon T, Hara Y. Gargling with tea catechin extracts forthe prevention of influenza infection in elderly nursing home residents: aprospective clinical study. J Altern Complem Med 12:669-672, 2006.
11. Yamada H, Yamada K, Waki M, Umegaki K. Lymphocyte and plasma vitamin C
levels in type 2 diabetic patients with and without diabetes complications.
Diabetes Care 27:2491-2492, 2004.
12. Yamada H, Ohashi K, Atsumi T, Okabe H, Shimizu T, Nishio S, Li XD, Kosuge K,Watanabe H, Hara Y. Effects of tea catechin Inhalation on methicillin-resistantStaphylococcus aureus in elderly patients in a hospital ward. J Hosp Infect53:229-231, 2003.
13. Yamada H, Nakashima M. New electronic device for monitoring medication
compliance. Am J Health-Syst Pharm 60:1910-1911, 2003.

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