Curriculum Vitae
Hiromu Kondo, Ph.D.
Professor,
Department of Pharmaceutical Engineering,
Division of Pharmacy,
School of Pharmaceutical Sciences, University of Shizuoka
52-1 Yada, Suruga-ku, Shizuoka 422-8526, Japan
Phone: +81-54-264-5614
Fax: +81-54-264-5614
Email: hkondo@u-shizuoka-ken.ac.jp

EDUCATION
Ph.D.
M.Ps.
B.Ps.

Pharmaceutical Science
Pharmaceutical Science
Pharmaceutical Science

Nihon University, 2003
Nagoya City University, 1993
Nagoya City University, 1991

QUALIFICATION
Pharmacist

1991

JOB/RESEARCH EXPERIENCE
Apr 2018 – present
Apr 2015 – Sep 2018
Apr 2013 – Mar 2018
Aug 2011 – Mar 2013
Apr 2005 – Jul 2011
Apr 1993 – Mar 2005

University of Shizuoka:
Professor, School of Pharmaceutical Sciences
Kyushu University:
Affiliate Professor, Pharmaceutical Science
Astellas Pharma Inc.:
Senior Director, Drug Delivery
OSI Pharmaceuticals, LLC (a wholly-owned subsidiary of Astellas USLLC):
Associate Director, Pharmaceutical Development Group
Astellas Pharma Inc.:
Research Fellow, Drug Delivery
Yamanouchi Pharmaceutical Co., Ltd.:
Researcher, Drug Delivery and Biopharmacy

RECENT RESEARCH INTEREST⚫
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Formulation design
Controlled release
Drug Delivery System
Nanofiber
Rheology

MEMBERSHIP⚫
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The Academy of Pharmaceutical Science and Technology, JapanThe Japan Society of Drug Delivery System
The Pharmaceutical Society of JapanThe Japanese Society for the Study of Xenobiotics
Japan Society of Pharmaceutical Machinery and Engineering

PUBLICTION⚫

Research articles (selected)

1. A. Kambayashi, K. Sako, H. Kondo. Scintigraphic evaluation of the in vivo performance ofdry-coated delayed release tablets in humans. Eur J Pharm Biopharm. 2020; 152:116-122.
doi.org/10.1016/j.ejpb.2020.04.022
2. M. T. Salam, A. Kumar, A. Hata, H. Kondo. Md. A. Salam, Mir I. I. Wahed, Md. R. I. Khan, R. K.
Barman. Accelerated Aqueous Solubility and Antibacterial Activity of Cefuroxime Axetil Using
Microcrystalline Cellulose as Carrier. Pharmacology & Pharmacy. 2020; 11, 159-173.
3. T. Yoshida, K. Sako, H. Kondo. Design of novel tacrolimus formulations with chemicallysynthesized oils for oral lymphatic delivery. Drug Dev Ind Pharm. 2020; 46(2): 219-226.
doi.org/10.1080/03639045.2020.1721525.
4. A. Kambayashi, K. Sako, H. Kondo. Characterization of the buccal and gastric transit of orally
disintegrating tablets in humans using gamma scintigraphy. Int J Pharm. 2020; 576: 118937, doi:
10.1016/j.ijpharm.2019.118937.
5. A. Kambayashi, K. Sako, H. Kondo. Effects of Diurnal Variation and Food on Gastrointestinal
Transit of 111In-Labeled Hydrogel Matrix Extended-Release Tablets and 99mTc-Labeled Pellets inHumans. J Pharm Sci. 2020; 109(2): 1020-1025, doi: 10.1016/j.xphs.2019.09.025.
6. R. Kiniwa, M. Miyake, S. Kimura, S. Itai, H. Kondo, Y. Iwao. Development of muco-adhesive
orally disintegrating tablets containing tamarind gum-coated tea powders for oral care. Int J
Pharm. 2019; doi: 10.1016/j.ijpx.2019.100012. eCollection 2019 Dec.
7. S. Kimura, T. Ishikawa, Y. Iwao, S. Itai, H. Kondo. Fabrication of Zero-Order Sustained-Release
Floating Tablets via Fused Depositing Modeling 3D Printer. Chem Pharm Bull. 2019; 67(9):992-999.
8. Y. Iwao, H. Ishida, S. Kimura, T. Wakimoto, H. Kondo, S. Itai, S. Noguchi. Crystal Structures ofFlavone C-Glycosides from Oolong Tea Leaves: Chafuroside A Dihydrate and Chafuroside B
Monohydrate. Chem Pharm Bull. 2019; 67(9): 935-939.
9. M. Kaihara, K. Hojo, T. Tajiri, A. Kambayashi, T. Yoshida, Y. Katakawa, K. Motonaga, S. Kimura,Y. Iwao, H. Kondo. Novel dissolution approach for tacrolimus-loaded microspheres using adialysis membrane for in vitro-in vivo correlation. Chem Pharm Bull. 2019; 67(5): 467-475.
10. K. Matsumoto, S. Kimura, S. Itai, H. Kondo, Y. Iwao. In vivo temperature-sensitive drug releasesystem trigged by cooling using low-melting-point microcrystalline wax. J Control Release 2019;
303: 281-288, doi: 10.1016/j.jconrel.2019.04.029.

11. K. Matsumoto, S. Kimura, S. Noguchi, S. Itai, H. Kondo, Y. Iwao. Mechanism of drug releasefrom temperature-sensitive formulations composed of low-melting-point microcrystalline wax. J
Pharm Sci. 2019; 108(6): 2086-2093, doi: 10.1016/j.xphs.2019.01.010.
12. S. Matsuo, K. Higashi, K. Moribe, S. Kimura, S. Itai, H. Kondo, Y. Iwao. Combination of roll
grinding and high-pressure homogenization can prepare stable bicelles for drug delivery.
Nanomaterials 2018; 8, 998: doi:10.3390/nano8120998.
13. M. Kobayashi, D. Shinozuka, H. Kondo, K. Sako, K. Otake. Novel orally disintegrating tablets
produced using a high-pressure carbon dioxides process. Chem Pharm Bull. 2018; 66: 932–938.
14. Y. Ito, A. Maeda, H. Kondo, Y. Iwao, S. Noguchi, S. Itai. Application of water-insoluble polymers
to orally disintegrating tablets treated by high-pressure carbon dioxide gas. Int J Pharm. 2016;
511(1): 10-22.
15. T. Yoshida, K. Nakanishi, T. Yoshioka, Y. Tsutsui, A. Maeda, H. Kondo, K. Sako. Oral tacrolimus
formulations for enhanced lymphatic delivery and efficient inhibilion of T-cells interleukin-2production. Euro J Pharm Biopharm. 2016; 100: 58-65.
16. T. Ishii, N. Kobayashi, A. Maeda, H. Kondo, K. Sako, S. Yamada, Y. Kagawa. Absorption
improvement of sepantronium bromide (YM155) by aminoalkyl methacrylate copolymers in insitu intestinal tracts of mice. J Drug Del Sci Tech. 2015; 27: 1-8.
17. S. Takemura, H. Kondo, S. Watanabe, K. Sako, K. Ogawara, K. Higaki. Aminoalkylmethacrylate
copolymer E improves oral bioavailability of YM466 by suppressing drug-bile interaction. JPharm Sci. 2013; 102(9): 3128-3135.
18. S. Takemura, H. Kondo, K. Suzumura, K. Ogawara, S. Watanabe, K. Sako, K. Higaki. Evaluationof factors affecting gastrointestinal absorption of a novel anticoagulant FX-93 for development oforal formulation. J Pharm Sci. 2012; 101(6): 2134-2142.
19. H. Kojima, K. Yoshihara, T. Sawada, H. Kondo, K. Sako. Extended release of a large amount ofhighly water-soluble diltiazem hydrochloride by utilizing counter polymer in polyethylene oxides(PEO)/polyethylene glycol (PEG) matrix tablets. Eur J Pharm Biopharm. 2008; 70: 556-562.
20. C. Mori and H. Kondo. Effect of gastric acidity regulation on the gastrointestinal transit time andsecretion of gastric fluids in beagle dogs. J Drug Del Sci Tech. 2006; 16(6): 467-472.
21. T. Sawada, H. Kondo, H. Nakashima, K. Sako, M. Hayashi. Time-release compression-coatedcore tablet containing nifedipine for chronopharmacotherapy. Int J Pharm. 2004; 280(1-2):
103-111.
22. H. Kondo, T. Watanabe, S. Yokohama, J. Watanabe. Effect of food on gastrointestinal transit ofliquids in unfed cynomolgus monkeys. Biopharm Drug Dispos. 2003; 24: 141-151.
23. H. Kondo, Y. Takahashi, T. Watanabe, S. Yokohama, J. Watanabe. Gastrointestinal transit ofliquids in unfed cynomolgus monkeys. Biopharm Drug Dispos. 2003; 24: 131-140.

24. H. Kondo, T. Shinoda, H. Nakashima, T. Watanabe, S. Yokohama. Characteristics of the gastricpH profiles of unfed and fed cynomolgus monkeys as pharmaceutical product development
subjects. Biopharm Drug Dispos. 2003; 24: 45-51.
25. Y. Takahashi, H. Kondo, T. Yasuda, T. Watanabe, S. Kobayashi, S. Yokohama. Common
solubilizers to estimate the Caco-2 transport of poorly water-soluble drugs. Int J Pharm. 2002;
246(1-2): 85-94.
26. J. Watanabe, H. Kondo, H. Muranishi, K. Urano, M. Haba, H. Yuasa.
Macromolecule-macromolecule interaction in drug distribution. III. Kinetic characterization of theuptake of fractionated [3H]heparin and the effect of plasma proteins in the perfused rat liver. BiolPharm Bull. 1993; 16(10): 1035-9.
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Review article

1.

T. Yasuji, H. Kondo, K. Sako. The effect of food on the oral bioavailability of drugs: a review ofcurrent developments and pharmaceutical technologies for pharmacokinetic control. Ther Deliv.
2012; 3(1): 81-90.