NAOKI YOSHIDA
University of Shizuoka, Junior College (Shizuoka, Japan)
Professor, Department of Dental Hygiene
Email: yoshidan@u-shizuoka-ken.ac.jp
Address: 2-2-1 Oshika, Suruga-Ward, Shizuoka-City, 422-8021 Japan
Education
1993 Ph.D Tokyo Medical and Dental University
1988 D.D.S.. Tokyo Medical and Dental University School of Dentistry1982 Graduated from High School
Employment
2014-present Professor, Department of Dental Hygiene, University of Shizuoka,
Junior College
1997-2014

Associate Professor, Department of Dental Hygiene, University ofShizuoka, Junior College

1994-1997

Research Associate, Department of Periodontology, Tokyo Medical andDental University School of Dentistry( 1996-1997

Postdoctoral Fellow, University of Kansas Medical Center, USA )1993-1994

Dental Staff (Dentist) in Periodontology, Tokyo Medical and Dental
University, Dental Hospital

1988-1989

Dental Staff (Dentist) in Periodontology, Tokyo Medical and Dental
University, Dental Hospital

Publications
Emiko Nakano, Naoki Yoshida, and Akihiro Yoshihara. Effects of the ketogenic diet for thepediatric patients’ oral health condition. J.Dent.Hlth. 70(1): 35-43, 2020. (in Japanese)
Yuki Noguchi, Yasuyo Kodama, Tomoko Morino, Naoki Yoshida, Yugo Ariizumi, andYoshinobu Maki. Dental health guidance on the use fluoride toothpaste provided by dental
hygienist. J.Japan. Soc. Dent. Hygiene. 11(1):34-43, 2016. (in Japanese)Naoki Yoshida and Kazuko Ebina. Differences between the first edition and the fourth editionof the textbook of clinical periodontology written by Jan Lindhe. Annual Report of Universityof Shizuoka, Shizuoka College. 27:51-55, 2014. (in Japanese)
Yukiko Bando, Kazuyuki Noguchi, Hiroaki Kobayashi, Naoki Yoshida, Isao Ishikawa, andYuichi Izumi. Cyclooxygenase-2-derived prostaglandin E2 is involved in vascular endothelial
growth factor production in interleukin-1α-stimulated human periodontal ligament cells. J.
Periodont. Res. 44: 395-401, 2009.
Kazuko Ebina, Naoki Yoshida. Effect of additional scaling training for dental hygiene course
students. J.Japan Soc. Dent. Hygiene. 1(2):74-79, 2007. (in Japanese)
Seiichiro Takeshita, Fumiyo Takabayashi, and Naoki Yoshida. Circulating adiponectin levels
in Kawasaki disease. Acta Paediatrica. 95: 1312-1314, 2006.
Noguchi K, Yoshida N, Kobayashi H, and Ishikawa I. Regulation of Interleukin-1β-induced
matrix metalloproteinase-1 production by prostaglandin E2 and interleukin-4 in humangingival fibroblasts. Jpn. J. Conseve. Dent. 48(4), 579-585, 2005. (in Japanese)
Noguchi K, Ruwanpura SMPM, Yan M, Yoshida N, and Ishikawa I. Down regulation ofinterleukin-1α-induced matrix metalloproteinase-13 expression via EP1 receptors byprostaglandin E2 in human periodontal ligament cells. Oral Microbiol Immunol. 20: 56-59,
2005.
Naoki Yoshida, Fumiyo Takabayashi, and Seiichiro Takeshita. An Outline of the Past
Research and the Outlook for the Matrix Metalloproteinases. Annual Report of University ofShizuoka, Shizuoka College.. 18:131-144, 2005. (in Japanese)
Seiichiro Takeshita, Fumiyo Takabayashi, and Naoki Yoshida. C (-260)→T polymorphism inthe promoter of CD 14 gene in Kawasaki disease. Annual Report of University of Shizuoka,Shizuoka College.. 18:45-50, 2005.
Takeshita S, Kawamura Y, Takabayashi F, Yoshida N, and Nonoyama S. Imbalance in theproduction between vascular endothelial growth factor and endostatin in Kawasaki disease.
Clin. Exp. Immunol.139: 575-579, 2005.

Kobayashi T, Nishikawa T, Hattori S, Yoshida N, Takagi T, Watanabe H, Hori H, and Nagai
Y. Systemic separation and purification of elastase, gelatinase (matrix metalloproteinase 9),and collagenase (matrix metalloproteinase 8) from polymorphonuclear leukocytes in dialyzers
previously used by patients with renal failure. Protein Expression and Purification 22: 45-51,
2001.
Naoki Yoshida. Role of Matrix Metalloproteinases in Periodontal Diseases. Annual Report ofUniversity of Shizuoka, Shizuoka College.. 14-2: 53-61, 2001. (in Japanese)
S. Arumugam, Christopher L. Hemme, Naoki Yoshida, Ko Suzuki, Hideaki Nagase, MarkBerjanskii, Bin Wu, and Steven R. Van Doren.TIMP-1 Contact Sites and Perturbations ofStromelysin 1 Mapped by NMR and a Paramagnetic Surface Probe. Biochemistry. 37(27):9650-9657, 1998.
Franz-Xaver Gomis-Ruth, Klaus Maskos, Michael Betz, Andreas Bergner, Robert Huber, KoSuzuki, Naoki Yoshida, Hideaki Nagase, Keith Brew, Gleb P.Bourenkov, Hans Bartunik, andWolfram Bode. Mechanism of inhibition of the human matrix metalloproteinase stromelysin1 by TIMP-1. Nature 389: 77-81, 1997.
Ishikawa I, Yoshida N, Sugiyama E, Kinoshita A, and Oda S. The effects of recombinanthuman bone morphogenetic protein-2 on periodontal tissues. Japanese Journal ofInflammation 16(3):181-185, 1996 (in Japanese)
Hagiwara S, Umeda M, Tominaga Y, Takamatsyu N, and Yoshida N. Subgingival distributionof periodontopathic bacteria in periodontitic patients and susceptibility of these bacteria tominocycline-HCl. J. Stomatological Society, Japan 62 (4): 495-505, 1995. (in Japanese)
Jose Ricardo Kina, Naoki Yoshida, Masae Goseki, Satoshi Sasaki, and Isao Ishikawa.
Properties of alkaline phosphatase in the gingival crevicular fluid．Bull Tokyo Med Dent Univ.
42(2): 57-65, 1995.
Shinjiro Odake, Yasuo Morita, Tadanori Morikawa, Naoki Yoshida, Hisae Hori, and YutakaNagai. Inhibition of matrix metalloproteinases by peptidyl hydroxamic acids ． Biochem
Biophys Res Commun 199(3): 1442-1446, 1994.

Naoki Yoshida. Purification of Human Neutrophil Collagenase, Establishment of its
Monoclonal Antibodies and Application to Gingival Crevicular Neutrophils. J. StomatologicalSociety, Japan 60 (1): 121-130, 1993. (in Japanese)