Curriculum Vitae (September 1st, 2022)

Satoshi SHIMIZU, Ph.D.
Research Assistant Professor
Department of Bio-Informational Pharmacology, School of PharmaceuticalSciences, University of Shizuoka
52-1 Yada, Surugaku, Shizuoka 420-0885, Japan
E-mail: s.shimizu@u-shizuoka-ken.ac.jp
Homepage: https://sites.google.com/view/kendaibip/

Education
Ph.D. in Pharmaceutical Science, March 2022
University of Shizuoka, Graduate School of Integrated Pharmaceutical andNutritional Sciences, Shizuoka, Japan (Prof. Tatsuya Morimoto)
Master of Science in Pharmaceutical Science, March 2018
University of Shizuoka, Graduate School of Integrated Pharmaceutical andNutritional Sciences, Shizuoka, Japan (Prof. Tatsuya Morimoto)
Bachelor of Science of Pharmaceutical Science, March 2016
University of Shizuoka, School of Pharmaceutical Sciences, Shizuoka, Japan(Prof. Tatsuya Morimoto)

Professional Experience
2022/9-present
Assistant Professor, University of Shizuoka, School of PharmaceuticalSciences, Shizuoka, Japan (Prof. Junko Kurokawa)
2022/4 - 2022/8
Postdoctoral fellow, The Jikei University School Medicine, Department ofLaboratory Medicine, Tokyo, Japan (Assoc. Prof. Shushi Nagamori)Honors and Awards
1. Biofunction and Drug Discovery symposium 2022, Best Presentation
Award, 2022
2. 142nd Annual Meeting of the Pharmaceutical Society of Japan, StudentBest Presentation Award, 2022
3. The 31st Annual Meeting of Japanese Association of CardiovascularPharmacology, Young Investigator Award, 2021
4. Biofunction and Drug Discovery symposium 2021, Poster Presentation
Award, 2021
5. The 6th Japan Cardiovascular Association, Young Investigator Award,2021
6. The 143rd Kanto Regional Meeting of the Japanese PharmacologicalSociety, Young Investigator Award, 2020
7. The 24th Shizuoka Forum on Health and Longevity, Best Presentation
Award, 20198. 21st Annual Symposium of Pharmacometrics, Best Poster Presentation
Award, 2019
9. Kowa Life Science Foundation, International Association Grand, 201910. 139th Annual Meeting of the Pharmaceutical Society of Japan, StudentBest Presentation Award, 2019
11. The 23rd Shizuoka Forum on Health and Longevity, Best Presentation
Award, 2018
12. The 4th International Conference on Pharma-Food 2018, PosterPresentation Award, 2018
13. The Pharmaceutical Society Japan Tokai Branch together with JapaneseSociety of Hospital Pharmacists Tokai Block 2018, Best Presentation
Award, 2018
14. IUBMB Focused Meeting on GATA Transcription Factors, Travel Award,2018
15. Asian Pacific Society of Cardiology Congress 2018, First Prize of theModerated Poster Competition, 201816. 1st Japan Circulation Society Council Forum on Basic Cardio VascularResearch, Poster Award, 2018
17. Quantum Beam Science Festa 2016, Student Encouragement Award,2017

Publications
1. Yoichi Sunagawa, Nobuko Okamura, Yusuke Miyazaki, Kana Shimizu,Mai Genpei, Masafumi Funamoto, Satoshi Shimizu, Yasufumi
Katanasaka, Eriko Morimoto, Hajime Yamakage, Maki Komiyama,
Noriko Satoh-Asahara, Hiromichi Wada, Mika Suzuki, Koji Hasegawa,
Tatsuya Morimoto*, Effects of Products Containing Bacillus subtilis var.
natto on Healthy Subjects with Neck and Shoulder Stiffness, a DoubleBlind, Placebo-Controlled, Randomized Crossover Study, Biologicaland Pharmaceutical Bulletin, 2018, 41, 504-509
2. Yoichi Sunagawa, Masafumi Funamoto, Shogo Sono, Kana Shimizu,
Satoshi Shimizu, Mai Genpei, Yusuke Miyazaki, Yasufumi Katanasaka,
Eriko Morimoto, Morio Ueno, Maki Komiyama, Hideaki Kakeya,
Hiromichi Wada, Koji Hasegawa, Tatsuya Morimoto*, Curcumin and its
demethoxy derivatives possess p300 HAT inhibitory activity andsuppress hypertrophic responses in cardiomyocytes, Journal ofPharamacological Sciences, 2018, 136, 212-217
3. Kana Shimizu, Masafumi Funamoto, Yoichi Sunagawa, SatoshiShimizu, Yasufumi Katanasaka, Yusuke Miyazaki, Hiromichi Wada,Koji Hasegawa, Tatsuya Morimoto*, Anti-inflammatory Action ofCurcumin and Its Use in the Treatment of Lifestyle-related Diseases,
European Cardiology Review, 2019, 14, 117-122
4. Yasufumi Katanasaka, Yusuke Miyazaki, Yoichi Sunagawa, Masafumi
Funamoto, Kana Shimizu, Satoshi Shimizu, Nurmila Sari, YasuoShimizu, Hiromichi Wada, Koji Hasegawa, Tatsuya Morimoto*, Kosencha, a Polymerized Catechin-Rich Green Tea, as a Potential Functional
Beverage for the Reduction of Body Weight and Cardiovascular RiskFactors: A Pilot Study in Obese Patients, Biological and PharmaceuticalBulletin, 2020, 43, 675-681
5. Kana Shimizu, Yoichi Sunagawa, Masafumi Funamoto, Hiroki
Wakabayashi, Mai Genpei, Yusuke Miyazaki, Yasufumi Katanasaka,Nurmila Sari, Satoshi Shimizu, Ayumi Katayama, Hiroyuki Shibata,
Yoshiharu Iwabuchi, Hideaki Kakeya, Hiromichi Wada, Koji Hasegawa,
Tatsuya Morimoto*, The Synthetic Curcumin Analogue GO-Y030
Effectively Suppresses the Development of Pressure Overload-induced
Heart Failure in Mice, Scientific Reports, 2020, 10, 71726. Nurmila Sari, Yasufumi Katanasaka, Hiroki Honda, Yusuke Miyazaki,
Yoichi Sunagawa, Masafumi Funamoto, Kana Shimizu, SatoshiShimizu, Hiromichi Wada, Koji Hasegawa, Tatsuya Morimoto*, Cacao
Bean Polyphenols Inhibit Cardiac Hypertrophy and Systolic Dysfunctionin Pressure Overload-induced Heart Failure Model Mice, Plants Medica,
2020, 86, 1304-1312
7. Masafumi Funamoto, Yoichi Sunagawa, Yasufumi Katanasaka, KanaShimizu, Yusuke Miyazaki, Nurmila Sari, Satoshi Shimizu, KiyoshiMori, Hidemichi Wada, Koji Hasegawa, Tatsuya Morimoto*, Histone
Acetylation Domains Are Differentially Induced during Development ofHeart Failure in Dahl Salt-Sensitive Rats, International Journal of
Molecular Sciences, 2021, 22, 1771
8. Yoichi Sunagawa, Kiyotaka Shimizu, Ayumi Katayama, Masafumi
Funamoto, Kana Shimizu, Sari Nurmila, Satoshi Shimizu, Yusuke
Miyazaki, Yasufumi Katanasaka, Koji Hasegawa, Tatsuya Morimoto*,
Metformin suppresses phenylephrine-induced hypertrophic responses byinhibiting p300-HAT activity in cardiomyocytes, Journal of
Pharmacological Sciences, 2021, 147, 169-175
9. Yoichi Sunagawa, Yusuke Miyazaki, Masafumi Funamoto, KanaShimizu, Satoshi Shimizu, Sari Nurmila, Yasufumi Katanasaka,Masashi Ito, Tatsuya Ogawa, Hitomi Ozawa-Umeta, Koji Hasegawa,Tatsuya Morimoto*, A novel amorphous preparation improved curcuminbioavailability in healthy volunteers: A single-dose, double-blind, twoway crossover study, Journal of Functional Foods, 2021, 81, 104443
10. Yoichi Sunagawa, Masafumi Funamoto, Kana Shimizu, SatoshiShimizu, Nurmila Sari, Yasufumi Katanasaka, Yusuke Miyazaki,Hideaki Kakeya, Koji Hasegawa, Tatsuya Morimoto*, Curcumin, anInhibitor of p300-HAT Activity, Suppresses the Development ofHypertension-Induced Left Ventricular Hypertrophy with PreservedEjection Fraction in Dahl Rats, Nutrients, 2021, 13, 2608
11. Nurmila Sari, Yasufumi Katanasaka, Yuga Sugiyama, Yoichi Sunagawa,Yusuke Miyazaki, Masafumi Funamoto, Satoshi Shimizu, KanaShimizu, Akira Murakami, Kiyoshi Mori, Hiromichi Wada, Koji
Hasegawa, Tatsuya Morimoto*, Zerumbone prevents pressure overloadinduced left ventricular systolic dysfunction by inhibiting cardiac
hypertrophy and fibrosis, Phytomedicine, 2021, 92, 153744

12. Nurmila Sari, Yasufumi Katanasaka, Yuga Sugiyama, Yusuke Miyazaki,
Yoichi Sunagawa, Masafumi Funamoto, Kana Shimizu, SatoshiShimizu, Koji Hasegawa, Tatsuya Morimoto*, Alpha Mangostin
Derived from Garcinia magostana Linn Ameliorates Cardiomyocyte
Hypertrophy and Fibroblast Phenotypes in Vitro, Biological andPharmaceutical Bulletin, 2021, 44, 1465-1472
13. Yasufumi Katanasaka, Naoki Yoshida, Hirotaka Naitou, Ryuya Naruta,Yusuke Miyazaki, Yoichi Sunagawa, Masafumi Funamoto, KanaShimizu, Satoshi Shimizu, Nurmila Sari, Hajime Yamakage, Noriko
Satoh-Asahara, Koji Hasegawa, Tatsuya Morimoto*, Effect ofTheaflavin on Oral Bacteria in Japanese Subjects: A Randomized,
Placebo-Controlled, Double-Blind Study, Journal of Medicinal Food,
2021, 24, 1186-1190
14. Yasufumi Katanasaka, Sae Hirano, Yoichi Sunagawa, Yusuke Miyazaki,Hikaru Sato, Masafumi Funamoto, Kana Shimizu, Satoshi Shimizu,
Nurmila Sari, Koji Hasegawa, Tatsuya Morimoto*, Clinically
Administered Doses of Pitavastatin and Rosuvastatin, InternationalHeart Journal, 2021, 62, 1379-1386
15. Kana Shimizu, Yoichi Sunagawa, Masafumi Funamoto, Hiroki Honda,Yasufumi Karanasaka, Noriyuki Murai, Yuto Kawase, Yuta Hirako,
Takahiro Katagiri, Harumi Yabe, Satoshi Shimizu, Nurmila Sari,Hiromichi Wada, Koji Hasegawa, Tatsuya Morimoto*, The SelectiveSerotonin 2A Receptor Antagonist Sarpogrelate Prevents Cardiac
Hypertrophy and Systolic Dysfunction via Inhibition of the ERK1/2GATA4 Signaling Pathway, Pharmaceuticals(Basel), 2021, 14, 1268
16. Satoshi Shimizu, Yoichi Sunagawa, Naruto Hajika, Natsumi Yorimitsu,
Yasufumi Katanasaka, Masafumi Funamoto, Yusuke Miyazaki, Nurmila
Sari, Kana Shimizu, Koji Hasegawa, Tatsuya Morimoto*,
Multimerization of the GATA4 transcription factor regulates
transcriptional activity and cardiomyocyte hypertrophic response,International Journal of Biological Sciences, 2022, 18, 1079-1095[cover future]
17. Masaya Ono, Yoichi Sunagawa, Saho Mochizuki, Takahiro Katagiri,
Hidemichi Takai, Sonoka Iwashimizu, Kyoko Inai, Masafumi Funamoto,
Kana Shimizu, Satoshi Shimizu, Yasufumi Katanasaka, MakiKomiyama, Philip Hawke, Hideo Hara, Yoshiko Arakawa, Kiyoshi Mori,Akira Asai, Koji Hasegawa, Tatsuya Morimoto*, Chrysanthemum
morifolium Extract Ameliorates Doxorubicin-Induced Cardiotoxicity by
Decreasing Apoptosis, Cancers(Basel), 2022, 14, 683
18. Takahiro Katagiri, Yoichi Sunagawa, Tatsuya Maekawa, Masafumi
Funamoto, Satoshi Shimizu, Kana Shimizu, Yasufumi Katanasaka,
Maki Komiyama, Philip Hawke, Hideo Hara, Kiyoshi Mori, Koji
Hasegawa, Tatsuya Morimoto*, Ecklonia stolonifera Okamura Extract
Suppresses Myocardial Infarction-Induced Left Ventricular Systolic
Dysfunction by Inhibiting p300-HAT Activity, Nutrients, 2022, 14, 580
19. Yoichi Sunagawa, Ayumi Katayama, Masafumi Funamoto, KanaShimizu, Satoshi Shimizu, Sari Nurmila, Yasufumi Katanasaka, Yusuke
Miyazaki, Ryota Hosomi, Koji Hasegawa, Tatsuya Morimoto, The
Polyunsaturated Fatty Acids, EPA and DHA, Ameliorate Myocardial
Infarction-induced Heart Failure by Inhibiting p300-HAT Activity inRats, The Journal of Nutritional Biochemistry, 2022, 106, 109031
20. Masafumi Funamoto, Yoichi Sunagawa, Mai Gempei, Kana Shimizu,
Yasufumi Katanasaka, Satoshi Shimizu, Toshihide Hamabe-Horiike,
Giovanni Appendino, Alberto Minassi, Andreas Koeberie, MakiKomiyama, Kiyoshi Mori, Koji Hasegawa, Tatsuya Morimoto, PyrazoleCurcumin Suppresses Cardiomyocyte Hypertrophy by Disrupting theCDK9/CyclinT1 Complex, Pharaceutics, 2022, 14, 1269