FLEXcyte 96
True Cardiac Contractilityand H i g h e r T h r o u g h p u t combined

Enablinginnovat]i[onFLEXcyte 96
True contractility.

Start your next generation assay

The FLEXcyte 96 technology has
been designed for higher
throughput in vitro cardiac

contractility recordings underphysiological mechanical conditions.

Gain from a format that goesbeyond standard 2D
monolayers of iPSC-CMs.

Your contractility data will translatebetter and more efficiently to humanphysiology.

Bringing physiologicalrelevanceand throughput together.
Welcome to pushing the boundaries•

Physiological mechanical conditions for your iPSC-CMs•

Pro-maturation environment•

96-well standard screening format•

Benchtop system with incubation lid•

Cost- and time-efficiency despite sophistication of the assay•

Straightforward data analysis•

Designed for research, quality control (QC) or drug screening

Movement of the membranes due tosynchronized cell beating is sensed
by electrodes via capacitive signals.
Signal sensing via our capacitive
sensor happens in the same way as amobile phone pen works.

Contractile force
FLEXcyte 96 is available as an add-on for the wellestablished CardioExcyte 96

Cells are cultured in a 96-well format on ultra-thin•

Physiological and label-free environment

silicone membranes, forming a biohybrid material•

Real-time cardiac contractility measurements

with

•

Accurate quantification of force-frequency

physiologically

relevant

mechanicalproperties. While being deflected by the weight ofrelation

the culture medium, rhythmic contraction of the•Detection of inotropic and chronotropic effects

cardiomyocytes lifts the membranes upwards.

•Compatible with CardioExcyte 96 technology

Your Software Cockpit
Powerful contractility analysis

CardioControl and DataControl

Heat maps

Data aquisition and analysis the easy way

Great tools•

Z-prime calculation•

Heat maps

Great ease-of-use•

Online Analysis•

Automated arrhythmia detection•

Calculation of concentration response curves•

Automated pdf report generation

Get a quick overview - e.g. response (%) tocompounds across 96 wells.

Maximizing your Data Output

Your goals and everyday challenges

We maximize data output at every stageYou'll never walk alone: Benefit from our service plans – you will receive unsurpassed application and technicalsupport and we ensure that you will have no downtime of the system.

B

enefit from our established cell handling protocols that we developed with cell suppliers.

Choose between two service plans: Premium and Basic. And get your hands – ontraining for free for new users.

Be like Laura!
"Do you also want more meaningful and cost efficient data from your iPSC-CM assay?"
You translate research into real outcomes for patients everywhere. With the FLEXcyte 96 technology you
get as close as never before to translatability of pharmacological results to human physiology.

See the full story here:

For screening service orders see www.innovitro.de
info@innovitro.de

For FLEXcyte 96 orders see www.nanion.de
info@nanion.decontact usnow!

“With the FLEXcyte 96 we are pushing the boundaries of iPSC-CM screening
by offering a physiological relevant assay in combination with highefficiency.”
Dr. Sonja Stoelzle-Feix, Director Scientfiic Affairs at Nanion

pushing t h eboundariesof iPSC-CM assays
Nanion EuropeNanion USANanion ChinaNanion Japaninfo@nanion.de

info@naniontech.com

andy.di@nanion.cn

ohtsuki@nanion.jp

phone: +49 89 2 190 95-0

phone: 1-888-9-NANION

phone: +86 10 82 17 6386

phone: +81 3 6457 8776

www.nanion.de

www.naniontech.com

www.nanion.cn

www.nanion.jp