Introduction

Staff

Advisory Committee

Advisory Board

Research Outline

Author Index

Biological Symposium

Foreign Visitors
Annual Report 2009 No. 60
Research Organization of Information and Systems
NATIONAL INSTITUTE OF GENETICSTo the National Institute of Genetics homepage

Annual Report 2009 No. 60
backIntroduction
The National Institute of Genetics (NIG) was established just 60 years ago in 1949 as thecentral institute to study various aspects of genetics. It was reorganized in 1984 as an interuniversity research institute to promote collaborations with researchers at universities. Since
1988, NIG has been participating in graduate education as the Department of Genetics of the
Graduate University for Advanced Studies (SOKENDAI). NIG also serves as a center forvarious genetic resources such as mutant strains, clones and vectors, and houses DDBJ, theDNA Data Bank of Japan, and a DNA sequencing center.
The history of NIG overlaps the period of a revolution in the field of life science. Genetics is
no longer a discipline to study the rules and mechanisms of heredity, but has become thebasis for all fields of life science. Molecular techniques now allow us not only to decipher theentire genome sequence of organisms including humans, but also to understand the detailsof higher biological phenomena: cell differentiation, morphogenesis, brain function, andevolution --- the history of life itself. Currently, 37 research groups are actively performing
pioneering and cutting-edge researches in these fields at NIG.
Recent generation of massive information on biological systems and their environment
calls for new directions in life sciences, such as bioinformatics, system-level analysis, andtheoretical approaches to extract knowledge from databases. In particular,so-called the next
generation DNA sequencing technology will revolutionize a wide range of life science. To thisend NIG sets up the facilities for the high-throughput DNA sequencing and massive data
analysis, which are used for collaborations in the research community.NIG has collected anddeveloped various bioresouces(mouse,rice etc.)from wild population for long time, which are
now excellent targets in the new genome era to understand the mechanisms, evolution anddiversity of life.
On the occasion of the 60th anniversary, we would appreciate your continuous supportand encouragement to NIG.
We welcome your comments and suggestions on our research activities and endeavors.
Yuji Kohara, Director-GeneralbackAnnual Report 2009 No. 60
back

Staff
MemberDirector-General
KOHARA, Yuji, D. Sc.
Vice-Director
GOJOBORI, Takashi, D. Sc.
KURATA, Nori, D. Ag.,professor
Member
1. Department of Molecular Genetics
YAMAO, Fumiaki, D. Sc., Head of the Department
Division of Molecular Genetics
FUKAGAWA, Tatsuo, D. Sc., Professor
HORI, Tetsuya, D. Ag., Assistant Professor
Division of Mutagenesis
YAMAO, Fumiaki, D. Sc., Professor
TSUTSUI, Yasuhiro, D.Med., Assistant Professor
Molecular Mechanism Laboratory
SEINO, Hiroaki, D. Sc., Assistant Professor
Division of Nucleic Acid Chemistry
NATSUME,Tohru, D. Med., Adjunct Professor
IWAI,Kazuhiro, D. Med., Adjunct Professor
2. Department of Cell Genetics
ARAKI, Hiroyuki, D. Sc., Head of the Department
Division of Cytogenetics
KOBAYASHI, Takehiko, D. Sc., Professor
IIDA,Tetsushi, D. Sc., Assistant Professor
Division of Microbial Genetics
ARAKI , Hiroyuki, D. Sc., Professor
TANAKA, Seiji, D. Sc., Assistant Professor
Division of Cytoplasmic Genetics
BALLING,Rudi, Ph. D., Adjunct Professor
KURODA, Shinya, D. Med., Adjunct Professor
3. Department of Developmental Genetics
HIROMI, Yasushi, D. Sc., Head of the Department
Division of Developmental Genetics
HIROMI, Yasushi, D. Sc., Professor
SHIMIZU, Hiroshi, D. Eng., Assistant Professor
ASAOKA, Miho, D. Sc., Assistant Professor
Division of Gene Expression
IWASATO,Takuji, D. Sc., Professor
MIZUNO, Hidenobu, D. Sc., Assistant Professor

Division of Molecular and Developmental Biology
KAWAKAMI, Koichi, D. Sc., Professor
ASAKAWA, Kazuhide, D. Sc., Assistant Professor
Division of Physiological Genetics
PATEL, Nipam, Ph. D., Adjunct Professor
KIMBLE, Judith E, Ph. D., Adjunct Professor
4. Department of Population Genetics
SAITOU, Naruya, Ph. D., Head of the Department
Division of Population Genetics
SAITOU, Naruya, Ph. D., Professor
TAKANO, Toshiyuki, D. Sc., Associate Professor
SUMIYAMA, Kenta, D. Sc., Assistant Professor
TAKAHASHI, Aya, D. Ag., Assistant Professor
Division of Evolutionary Genetics
AKASHI,Hiroshi, D. Sc., Professor
OSADA, Naoki, Ph. D., Assistant Professor
Division of Theoretical Genetics
WU, Chung-I, Ph. D., Adjunct Professor
HASEGAWA, Masami, D. Sc., Adjunct Professor
HARTL, Daniel L, Adjunct Professor
5. Department of Integrated Genetics
SASAKI, Hiroyuki, D. Med., Head of the Department
Division of Human Genetics
SASAKI, Hiroyuki, D. Med., Professor
ICHIYANAGI, Kenji, D. Sc., Assistant Professor
Division of Agricultural Genetics
KAKUTANI, Tetsuji, D. Sc., Professor
SHIBAHARA, Kei-ichi, M. D.,Ph. D., Associate Professor
NISHIJIMA, Hitoshi, Ph. D., Assistant Professor
SAZE,Hidetoshi,Ph.D.,Assistant Professor
Division of Brain Fanction
HIRATA, Tatsumi, D. Med., Associate Professor
KAWASAKI, Takahiko, D. Sc., Assistant Professor
Division of Applied Genetics
SHINKAI, Yoichi, D. Med., Adjunct Professor
KADOWAKI, Takashi, D. Med., Adjunct Professor
COLOT, Vincent, Adjunct Professor
6. Genetics Strains Research Center
SHIROISHI, Toshihiko, D. Sc., Head of the Center
Mammalian Genetics Laboratory
SHIROISHI, Toshihiko, D. Sc., Professor
TAMURA, Masaru, D. Sc., Assistant Professor
TAKADA, Toyoyuki, D. Ag., Assistant Professor
Mammalian Development Laboratory
SAGA, Yumiko, D. Sc., Professor
KOKUBO, Hiroki, D. Sc., Assistant Professor
Mouse Genomics Resource Laboratory
KOIDE, Tsuyoshi, D. Med., Associate Professor
Model Fish Genomics Resource Laboratory
SAKAI, Noriyoshi, Ph. D., Associate Professor
SHINYA, Minori, D. Sc., Assistant Professor
Plant Genetics Laboratory
KURATA, Nori, D. Ag., Professor
KUBO, Takahiko, D. Ag., Assistant Professor

Microbial Genetics Laboratory
NIKI, Hironori, D. Med., Professor
FURUYA, Kanji, D. Sc., Assistant Professor
Invertebrate Genetics Laboratory
UEDA, Ryu, D. Sc., Professor
TAKAHASHI, Kuniaki, D. Sc., Assistant Professor
7. Center for Genetic Resource Information
SHIROISHI, Toshihiko, D. Sc., Head of the Center
Genetic Informatics Laboratory
YAMAZAKI, Yukiko, D. Sc., Associate Professor
Genomu Biology Laboratory
KOHARA, Yuji, D. Sc., Professor
ANDACHI, Yoshiki, D. Sc., Assistant Professor
Comparative Genomics
FUJIYAMA,Asao, D.Sc., Professor
TOYODA,Atsushi,D.Sc.,Associate Professor
8. Structral Biology Center
SHIMAMOTO, Nobuo, D. Sc., Head of the Center
Biological Macromolecules Laboratory
MAESHIMA, Kazuhiro, D. Med., Professor
Molecular Biomechanism Laboratory
SHIMAMOTO, Nobuo, D. Sc., Professor
NAKAYAMA, Hideki, D. Eng., Assistant Professor
Biomolecular Structure Laboratory
SHIRAKIHARA, Yasuo, D. Sc., Associate Professor
ITO, Hiroshi, D. Sc., Assistant Professor
Gene Network Laboratory
SUZUKI, Emiko, D. Med., Associate Professor
KURUSU, Mitsuhiko, D. Sc., Assistant Professor
9. Center for Information Biology and DNA Data Bank of JapanOKUBO, Kousaku, M. D. Ph. D., Professor., Head of the Center
Laboratory for DNA Data Analysis
GOJOBORI, Takashi, D. Sc., Professor
IKEO, Kazuho, D. Sc., Associate Professor
SUZUKI, Yoshiyuki, M. D., Ph. D., Assistant Professor
FUKUCHI, Satoshi, D. Sc., Assistant Professor
Laboratory for Gene-Product Informatics
NAKAMURA, Yasukazu,D. Sc., Professor
KAMINUMA, Eli, D. Eng., Assistant Professor
Laboratory for the Research and Development of Biological Databases
TAKAGI, Toshihisa, D. Eng., Professor
SUGAWARA, Hideaki, D. Eng., Professor
IWAYANAGI,Takao, D. Eng., Professor
Laboratory for Gene-Expression Analysis
OKUBO, Kousaku, M. D., Ph. D., Professor
OGASAWARA, Osamu, D. Sc., Assistant Professor
10. Center for Frontier Research
KURATA, Nori, D. Ag., Head of the Center
Neural Morphogenesis Laboratory
EMOTO, Kazuo, D. Pharm., Associate Professor
Cell Architecture Laboratory
KIMURA, Akatsuki, D. Sc., Associate Professor

11. Radioisotope Center
NIKI, Hironori, D. Med., Head of the Center
12. Experimental FarmNONOMURA, Ken-ichi, D. Ag., Associate Professor / Head of the Farm
MIYAZAKI, Saori, D. Ag., Assistant Professor
13. Intellectual Property UnitSUZUKI, Mutsuaki, D. Pharm., Director
14. Technical Section
KURATA, Nori, Deputy Chief of the Section
YATA, Katsunori, Assistant Chief of the Section
15. Department of Administration
UCHIYAMA,Akira, Head of the Department
KOKUDAI,Masatoshi, Chief of the Research Promotion Section
HIROSE,Hisayuki, Chief of the Management Project SectionbackAnnual Report 2009 No. 60
backAdvisory Committee
Advisory committee
Chairman
KURATA, Nori; Professor, Genetic Strains Research Center
Vice-chairman
SEKIGUCHI, Mutsuo; Adjunct Professor, Fukuoka Dental College
Outside Members (Alphabetical order)
KONDO,Shigeru; Professor, Graduate school of Medicine, Tohoku University
NAKAMURA, Haruki; Professor, Institute for Protein Research, Osaka University
NISHIDA, Eisuke; Professor, Graduate school of Biostudies, Kyoto University
OGAWA, Tomoko; Vice-Director, Iwate College of Nursing
OKADA, Norihiro; Professor, Department of Bioscience and Biotechnology, Tokyo Instituteof Technology
OSUMI, Noriko; Professor, Graduate School of Medicine, Tohoku University
SHINOZAKI, Kazuo; Director, Plant Science Center, RIKENSUGANO,Sumio; Professor, Graduate School of Frontier Sciences, The University ofTokyo
TACHIDA, Hidenori; Professor, Faculty of Sciences, Kyusyu University
Inside Members (Alphabetical order)
ARAKI, Hiroyuki; Professor, Department of Cell Genetics
GOJOBORI, Takashi; Professor, Center for Information Biology and DNA Data Bank ofJapan
HIROMI, Yasushi; Professor, Department of Developmental Genetics
NIKI, Hironori; Professor, Genetic Strains Research Center
KURATA, Nori; Professor, Genetic Strains Research Center
OKUBO,Kousaku; Professor, Center for Information Biology and DNA Data Bank of JapanSAITOU, Naruya; Professor, Department of Population Genetics
SASAKI, Hiroyuki; Professor, Department of Integrated Genetics
SHIMAMOTO, Nobuo; Professor, Structural Biology Center
SHIROISHI, Toshihiko; Professor, Genetic Strains Research Center
YAMAO, Fumiaki; Professor, Department of Molecular GeneticsbackAnnual Report 2009

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Advisory Board
ADVISORY BOARD
Members ( Alphabetical order)
GEHRING, Walter J.; Professor, Biozentrum, University of Basel
HUNT, Tim; Principal Scientist, Cancer Research UK London Research Institute
IWATSUKI, Kunio; Director-General, Museum of Nature and Human Activities, Hyogo
SAKAKI, Yoshiyuki; Director, Genomic Sciences Center, RIKEN
SUGIMURA, Takashi; President Emeritus, National Cancer Center
SULSTON, John; Former Director-General, Wellcome Trust Sanger Institute
TAKEICHI, Masatoshi; Director, Center for Developmental Biology, RIKENWIESCHAUS, Eric; Professor, Princeton UniversitybackAnnual Report 2009

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Research Outline
Code Division/Laboratory
A-a Division of Molecular Genetics
A-b Division of Mutagenesis
A-c Molecular Mechanism Laboratory
B-a Division of Cytogenetics
B-b Division of Microbial Genetics
C-a Division of Developmental Genetics
C-a Division of Developmental Genetics
C-b Division of Neurogenetics
C-b Division of Gene Expression
C-c Division of Molecular and Developmental Biology
D-a Division of Population Genetics
D-a Division of Population Genetics
D-b Evolutionary Genetics
E-a Division of Human Genetics
E-b Division of Agricultural Genetics
E-b Division of Agricultural Genetics
E-c Division of Brain Function
F-a Mammalian Genetics Laboratory
F-b Mammalian Development Laboratory
F-c Mouse Genomics Resource Laboratory
F-d Model Fish Genomics Resource
F-e Plant Genetics Laboratory
F-f Microbial Genetics Laboratory
F-g Invertebrate Genetics Laboratory
G-a Genetic Informatics Laboratory
G-b Genome biology Laboratory
G-c Comparative Genomics Laboratory
H-a Biological Macromolecules
H-b Molecular Biomechanism Laboratory
H-d Biomolecular Structure Laboratory
H-e Gene Network Laboratory
I-aLaboratory for DNA Data Analysis
I-b
Laboratory for Gene-Product Informatics
I-c
Laboratory for Gene Function Research
I-dLaboratory for Research and Development of Biological
Databases

Group name
Tatsuo Fukagawa
Fumiaki Yamao
Hiroaki Seino
Takehiko Kobayashi
Hiroyuki Araki
Yasushi Hiromi
Hiroshi Shimizu
Takuji Iwasato
Susumu Hirose
Koichi Kawakami
Naruya Saitou
Toshiyuki Takano
Hiroshi Akashi
Hiroyuki Sasaki
Tetsuji Kakutani
Keiichi Shibahara
Tatsumi Hirata
Toshihiko Shiroishi
Yumiko Saga
Tsuyoshi Koide
Noriyoshi Sakai
Nori Kurata
Hironori Niki
Ryu Ueda
Yukiko Yamazaki
Yuji Kohara
Asao Fujiyama
Kazuhiro Maeshima
Nobuo Shimamoto
Yasuo Shirakihara
Emiko Suzuki
Takashi Gojobori
Yasukazu Nakamura
Yoshio Tateno
Toshihisa Takagi

I-d
I-e
J-b
J-c
K

Laboratory for Research and Development of Biological
Databases
Laboratory for Gene-Expression Analysis
Neural Morphogenesis Laboratory
Cell Architecture Laboratory
RADIOISOTOPE CENTERL

EXPERIMENTAL FARM

MIntellectual Property Unit

N

Technical Section

Hideaki Sugawara
Kousaku Okubo
Emoto Kazuo
Kimura Akatsuki
RADIOISOTOPE
CENTER
EXPERIMENTAL
FARMIntellectual Property
Unit
Technical SectionbackAnnual Report 2009

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A. DEPARTMENT OF MOLECULAR GENETICS
A-a. Division of Molecular Genetics
A. DEPARTMENT OF MOLECULAR GENETICS
A-a. Division of Molecular Genetics
Tatsuo Fukagawa
RESEARCH ACTIVITIESPUBLICATIONSPapers
1 . Kong, X., Ball, A.R. Jr., Sonoda, E., Feng, J., Takeda, S., Fukagawa, T., Yen, T.J.,and
Yokomori K. ( 2008 ) Cohesin Associates with Spindle Poles in a Mitosis-specific Mannerand Functions in Spindle Assembly in Vertebrate Cells , Mol. Biol. Cell , 20 , 1289 - 1301
2 . Iwamoto, M., Mori,C., Kojidani, T., Bunai, F., Hori, T.,Fukagawa, T., Hiraoka, Y.,and
Haraguchi, T. ( 2009 ) Two Distinct Repeat Sequences of Nup98 Nucleoporins
Characterize Dual Nuclei in the Binucleated Ciliate Tetrahymena. , Curr. Biol. , 19 , 843 847
3 . Kawashima, T., Bao, Y.C., Minoshima ,Y., Nomura, Y., Hatori, T., Hori, T., Fukagawa, T.,
Fukada, T., Takahashi, N., Nosaka, T., Inoue, M., Sato, T., Kukimoto-Niino, M., Shirouzu, M.,
Yokoyama, S., and Kitamura, T. ( 2009 ) A Rac GTPase-activating protein, MgcRacGAP,
is a nuclear localizing signal-containing nuclear chaperone in the activation of STAT
transcription factors. , Mol. Cell. Biol. , 29 , 1796 - 1813
4 . Akagi, T., Fukagawa, T., Kage, Y., To, H., Matsunaga, N., Koyanagi, S., Uchida, A.,
Fujii, A., Iba, H., Ikemura, T., Aramaki, H., Higuchi, S., and Ohdo, S. ( 2009 ) Role ofglucocorticoid receptor in the regulation of cellular sensitivity to irinotecan hydrochloride. ,J. Pharmacol. Sci. , 109 , 265 - 274
5 . Amano, M., Suzuki, A., Hori, T., Backer, C., Okawa, K., Cheeseman, I.M., andFukagawa, T. ( 2009 ) The CENP-S complex is essential for the stable assembly of outerkinetochore structure. , J. Cell Biol. , 186 , 173 - 182
6 . Okada, M., Okawa, K., Isobe, T., and Fukagawa, T. ( 2009 ) CENP-H-containing
complex facilitates centromere deposition of CENP-A in cooperation with FACT and
CHD1. , Mol. Biol. Cell , 20 , 3986 - 3995
7 . Nishimura, K., Fukagawa, T., Takisawa, H., Kakimoto, T., and Kanemaki, M. ( 2009 )An auxin-based degron system for the rapid depletion of proteins in nonplant cells. , Nature
Methods , 6 , 917 - 922
8 . Xu, Z., Ogawa, H., Vagnarelli, P., Bergmann, J.H., Hudson, D.F., Ruchaud, S.,
Fukagawa, T., Earnshaw, W.C., and Samejima, K. ( 2009 ) INCENP-aurora B interactions
modulate kinase activity and chromosome passenger complex localization. , J. Cell Biol. ,187 , 637 - 653
9 . 堀哲也, 深川竜郎 ( 2009 ) セントロメアでのクロマチン構造の形成に必要なヒストンバリア
ントとDNA結合 , 蛋白質核酸酵素 , 54 , 1276 - 1283
10 . 深川竜郎 ( 2009 ) 染色体分配に必須なキネトコア構造の分子構築 , 遺伝 , 63 , 71 78
11 . 深川竜郎 ( 2009 ) 染色体分配に必要な動原体の分子構築 , 実験医学 , 27 , 2732 -2739
ORAL PRESENTATION
1 . Fukagawa, T.
Molecular architecture of the vertebrate constitutive centromere
associated network University of North Carolina 6/27
POSTER PRESENTATIONS
1 . 堀 哲也、天野美保、鈴木應志、深川竜郎 「 キネトコアに局在するDNA結合タンパク質の機能分担 」, 第２６回染色体ワークショップ , 姫路 , 1/26-28
2 . 深川竜郎 「 核内ダイナミクスの基盤となるセントロメア構造 」, 第81回日本遺伝学会 ミニ
シンポジウム , 松本 , 9/16
3 . Fukagawa, T. 「 Molecular structure of the vertebrate kinetochore 」, 第32回日本分子生物学会年会シンポジウム , 横浜 , 12/11
4 . Fukagawa, T. 「 Molecular architecture of the vertebrate constitutive centromere
associated network 」, 17th International Chromosome conference , Boone, NC , 6/25
5 . Fukagawa, T. 「 Molecular architecture of the vertebrate constitutive centromere
associated network 」, 17th International Chromosome conference , Boone, NC , 6/25
6 . Fukagawa, T. 「 Molecular architecture of the vertebrate constitutive centromere
associated network (CCAN) 」, Next-Generation Cancer and Genome Biology , Kyoto ,11/2
7 . Lampson, M.A. ,Liu, D.,Vleugel, M.,Backer, C.B.,Hori, T.,Fukagawa T.,Cheeseman, I.M.
「 Regulation of kinetochore-microtubule attachments by opposing kinase and phosphataseactivities. 」, 第32回日本分子生物学会年会シンポジウム , 横浜 , 12/11
8 .
堀 哲也,立和名博昭,越阪部晃永,大川克也,小布施力史,胡桃阪仁志,深川竜郎「
Structural feature of the CENP-A nucleosome in the vertebrate centromere. 」, 第32回日本
分子生物学会年会 , 横浜 , 12/10
9 . 鈴木應志,堀 哲也,深川竜郎 「 The inner plate in vertebrate kinetochore is flexible under
tension. 」, 第32回日本分子生物学会年会 , 横浜 , 12/9
10 .
堀 哲也,立和名博昭,越阪部晃永,大川克也,小布施力史,胡桃阪仁志,深川竜郎「
Structural feature of the CENP-A nucleosome in the vertebrate centromere. 」, 第32回日本
分子生物学会年会 , 横浜 , 12/10
11 . 商 維昊,堀 哲也,豊田 敦,藤山秋佐夫,深川竜郎 「 Characterization of Chicken
Centromere DNA. 」, 第32回日本分子生物学会年会 , 横浜 , 12/10
12 . Perpelescu, M.,野崎直仁,小布施力史,依田欣哉,深川竜郎 「 Active establishment of
CENP-A chromatin by remodeling factor Rsf-1/RSF. 」, 第32回日本分子生物学会年会 , 横
浜 , 12/10
13 . 竹内康造,堀 哲也,立和名博昭,越阪部晃永,胡桃阪仁志,深川竜郎 「 セントロメアDNA結合タンパク質CENP-T/CENP-W複合体の生化学的解析. 」, 第32回日本分子生物学会年会 ,横浜 , 12/10
14 . 越阪部晃永,野澤竜介,立和名博昭,,小布施力史,深川竜郎,胡桃阪仁志 「 新規ヒストン結合因子SPTY2D1の機能解析. 」, 第32回日本分子生物学会年会 , 横浜 , 12/11
15 . 山本拓弥,宇田川紘司,松村祐紀,横尾岳大,,深川竜郎,大山隆 「 人工ベントDNAにより活性化されたトランスジーンの核内局在：HeLa細胞を用いた解析. 」, 第32回日本分子生物学会
年会 , 横浜 , 12/11
16 . 宇田川紘司,山本拓弥,棚瀬潤一,深川竜郎,大山 隆 「 人工ベントDNAにより活性化されたトランスジーンの核内局在：マウスES細胞を用いた解析. 」, 第32回日本分子生物学会年会, 横浜 , 12/11
17 . 景山 大,中田勇人,木村 元,古屋美香,荒川 潤,深川竜郎,大山 隆 「 ヒトゲノムDNAにおける物性特異領域の生物学的意義：動態解析の試み 」, 第32回日本分子生物学会年会 ,横浜 , 12/11
18 . 古屋美香,荒川 潤,木村 元,景山 大,堀 哲也,深川竜郎,大山 隆 「 ヒトゲノムの物理的特性とクロマチン構造. 」, 第32回日本分子生物学会年会 , 横浜 , 12/11
19 . 北村大志,大渕恵理,小布施力史,田辺秀之,堀 哲也,深川竜郎,原田昌彦 「 クロマチン核
内配置におけるアクチン関連タンパク質Arp6の機能解析. 」, 第32回日本分子生物学会年会 ,横浜 , 12/11

20 . 西村浩平,深川竜郎,柿本辰男,滝澤温彦,鐘巻将人 「 植物ホルモン・オーキシン依存的タ
ンパク質分解系を応用した迅速なタンパク質除去法による出芽酵母と動物細胞コンディショナ
ル変異株の作成-オーキシン誘導デグロン法- 」, 第32回日本分子生物学会年会 , 横浜 ,12/12
EDUCATION
1 . 深川竜郎、野々村賢一 核ダイナミクス研究の新展開 第81回日本遺伝学会 ミニシンポ
ジウム 松本 9/16
2 . 深川竜郎、原田昌彦 クロマチン・染色体の分子構築と機能制御 遺伝研研究集会 三島
11/12
3 . Fukagawa, T., and I.M. Cheeseman
Centromere and Kinetochore-microtubuleinteractions 第32回日本分子生物学会年会シンポジウム 横浜 12/11
4 . 深川竜郎、石川冬木 次世代がんゲノム集会 三島 8/13
PATENT1 . 2009-110449 , 真核生物におけるオーキシンを用いたタンパク質発現制御法 , 西村浩平、柿本辰男、深川竜郎、滝澤温彦 , 国立大学法人大阪大学、大学共同利用機関法人情報・システム研究機backAnnual Report 2009

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A. DEPARTMENT OF MOLECULAR GENETICS
A-c. Molecular Mechanism Laboratory
A. DEPARTMENT OF MOLECULAR GENETICS
A-c. Molecular Mechanism Laboratory
Hiroaki Seino
RESEARCH ACTIVITIESPOSTER PRESENTATIONS
1 . Seino, H. 「 Ubiquitin-conjugating enzyme Ubc11 regulates DNA-damage checkpoint
signaling pathway. 」, The 32th Annual Meeting of The Molecular Biology Society of Japan ,Yokohama , 12back

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B. DEPARTMENT OF CELL GENETICS
B-a. Division of Cytogenetics
B. DEPARTMENT OF CELL GENETICS
B-a. Division of Cytogenetics
Takehiko Kobayashi
RESEARCH ACTIVITIESPUBLICATIONSPapers
1 . 小林 武彦 ( 2009 ) 複製、組換え、転写のコラボレーションによる遺伝子増幅 , 蛋白質、
核酸、酵素 , 54 , 537 - 542
2 . Ganly, A.R.D., Ide, S., Saka, K., and Kobayashi T. ( 2009 ) The effect of replication
initiation on gene amplification in the rDNA and its relationship to aging. , Molecular Cell ,35 , 683 - 693
3 . 小林 武彦 ( 2009 ) リボソームRNA遺伝子の新しい機能 , 化学と生物 , 47 , 104 - 110
POSTER PRESENTATIONS
1 . 小林 武彦 「 Recovery of rDNA stability contributes to rejuvenation in yeast. 」, 第32回日
本分子生物学会 , 横浜市 , 12
2 . Kobayashi, T. 「 The effect of replication initiation on gene amplification in the rDNA and
its relationship to aging. 」, International Symposium on chromosome cycle and genome
dynamics. , 栃木県那須市 , 11
3 . 小林 武彦 「 rDNAの不安定化と細胞老化 」, 第20回複製・組換え・修復ワークショップ ,滋賀 , 114 . 小林 武彦 「 リボソームRNA遺伝子のExtra copyの機能 」, 酵母遺伝学フォーラム第42回研究報告会 , つくば市 , 7backAnnual Report 2009

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B. DEPARTMENT OF CELL GENETICS
B-b. Division of Microbial Genetics
B. DEPARTMENT OF CELL GENETICS
B-b. Division of Microbial Genetics
Hiroyuki Araki
RESEARCH ACTIVITIESPUBLICATIONSPapers
1 . Tanaka, H., Katou, Y., Yagura, M., Saitoh, K., Itoh, T., Araki, H., Bando, M. andShirahige, K. ( 2009 ) Ctf4 coordinates the progression of helicase and DNA Polymerase
α. , Genes to Cells , 14 , 807 - 820
2 . Komata, M., Bando, M., Araki, H. and Shirahige, K. ( 2009 ) The direct binding of Mrc1,
a checkpoint mediator, to Mcm6, a replication helicase, is essential for the replication
checkpoint against methyl methanesulfonate-induced stress. , Mol. Cell. Biol. , 29 , 5008
- 50193 . Araki, H. ( 2009 ) Regulatory mechanism of the initiation step of DNA replication by
CDK in budding yeast. , Biochimica et Biophysica Acta , 1804 , 520 - 523
4 . 田中誠司、荒木弘之 ( 2009 ) 真核細胞の細胞周期制御機構と染色体DAN複製 , 遺伝 ,63 , 51 - 58
5 . 荒木弘之 ( 2008 ) 真核生物染色体DNAの複製開始を担う複製蛋白質複合体の形成 ,蛋白質核酸酵素 , 54 , 350 - 355
POSTER PRESENTATIONS
1 . Araki, H.,Hirai, K., Li, Y., Tanaka, T., Muramatsu, S., Tanaka, S., 「 CDK-Dependent
Assembly of Replication Proteins at the Initiation Step of Chromosomal DNA Replication 」,
Annual Meeting of American Society for Biochemistry and Molecular Biology , New
Orleans, USA , 4/18〜4/22
2 . Araki, H.,Hirai, K., Li, Y., Tanaka, T., Muramatsu, S., Tanaka, S. 「 CDK-Dependent
Assembly of Replication Proteins at the Initiation Step of Chromosomal DNA Replication 」,
Chromosome Dynamics and Genome Stability , Villars-sur-Ollons, Switzerland , 5/14〜
5/16
3 . Araki, H.,Hirai, K., Li, Y., Tanaka, T., Muramatsu, S., Tanaka, S. 「 CDK-dependent
assembly of replication proteins at the initiation step of chromosomal DNA replication 」,
Inhibitors of Protein Kinases , Warsaw, Poland , 6/27〜7/1
4 . 荒木弘之、村松佐知子、平井和之、柳沢好美、田中尚美、田中誠司 「 真核生物における染色体DNA複製開始の制御機構 」, 第82回 日本生化学会大会 , 神戸 , 10/21〜10/24
5 . Tanaka,S., Araki,H. 「 Multiple regulatory mechanisms of the initiation of DNA
replication are important for stable genome maintenance 」, 2009年度 複製・組換え・修復
ワークショップ , 彦根 , 11/2
6 . Tanaka, S.,Araki, H. 「 Multiple regulatory mechanisms for the initiation of DNA
replication are important for stable genome maintenance 」, Chromosome Dynamics andGenome Stability , Villars-sur-Ollons, Switzerland , 5/14〜5/16

7 . 田中誠司、荒木弘之 「 DNA複製開始制御システムとゲノム安定維持 」, 酵母遺伝学フォーラム第42回研究報告会 , つくば , 7/28〜7/30
8 . 田中誠司、荒木弘之 「 Multiple regulatory mechanisms for the initiation of DNA
replication are important for stable genome maintenance 」, 関東東海DNA研究会 , 強羅 ,7/23〜7/24
9 . 平井和之、荒木弘之 「 染色体DNAの複製開始期に形成されるタンパク質複合体の解析」, 関東東海DNA研究会 , 強羅 , 7/23〜7/24
10 . 矢倉勝、荒木弘之 「 出芽酵母 in vitro DNA複製系の構築に向けた解析 」, 関東東海
DNA研究会 , 強羅 , 7/23〜7/24
11 . Araki, H.,Hirai, K., Li, Y., Tanaka, T., Muramatsu, S., Tanaka, S. 「 CDK-dependent
assembly of replication proteins at the initiation step of chromosomal DNA replication 」,
Eukaryotic DNA Replication & Genome Maintenance , NY, USA , 9/1〜9/5
12 . Tanaka,S., Araki,H. 「 Multiple regulatory mechanisms of the initiation of DNA
replication are important for stable genome maintenance 」, Eukaryotic DNA Replication &Genome Maintenance , NY, USA , 9/1〜9/5
13 . Hirai, K., Muramatsu, S., Araki, H. 「 Protein assembly in the initiation stage of DNA
replication in budding yeast 」, Eukaryotic DNA Replication & Genome Maintenance , NY,
USA , 9/1〜9/5
14 . Yagura, M., Araki, H. 「 Functions of MCM10 in chromosomal DNA replication inbudding yeast 」, Eukaryotic DNA Replication & Genome Maintenance , NY, USA , 9/1〜
9/5
15 . 荒木弘之 「 遺伝学的手法を用いた新規複製因子の分離と解析：真核生物の複製開始機
構に迫る 」, 日本遺伝学会第81回大会 , 松本 , 9/16〜9/18
16 . 平井和之、村松佐知子、荒木弘之 「 染色体DNAの複製開始期に形成されるタンパク質複合体の解析 」, 日本遺伝学会第81回大会 , 松本 , 9/16〜9/18
17 . 矢倉勝、荒木弘之 「 出芽酵母染色体DNA複製におけるMCM10の機能解析 」, 日本遺伝学会第81回大会 , 松本 , 9/16〜9/18
18 . 田中誠司、 荒木弘之 「 Temporal regulation of origin firing in budding yeast
Saccharomyces cerevisiae. 」, 第32回日本分子生物学会年会 , 横浜 , 12/8〜12/12
19 . 荒木 弘之、 牧野 仁志穂、 本間 良美、大吉 崇文、 瓜谷 眞裕、 丑丸 敬史 「 TORによるNog1を介したMcm3安定性の制御
TOR regulates Mcm3 stability through Nog1 in thebudding yeast 」, 第32回日本分子生物学会年会 , 横浜 , 12/8〜12/12
20 . 平井 和之, 村松 佐知子, 荒木 弘之 「 Protein assembly in the initiation stage of DNA
replication in budding yeast 」, 第32回日本分子生物学会年会 , 横浜 , 12/8〜12/12
21 . 矢倉 勝、荒木 弘之 「 出芽酵母染色体DNA複製におけるMCM10の機能解析 Functionsof MCM10 in Chromosomal DNA Replication in Buddkng Yeast 」, 第32回日本分子生物学会年会 , 横浜 , 12/8〜12/12
22 . 荒木弘之、村松佐知子、平井和之、柳沢好美、田中尚美、田中誠司 「 真核生物における染色体DNA複製開始の制御機構 」, 生命活動を制御する高次複合体の構造と機能 , 福岡
, 12/22〜12/23
BOOK
1 . 荒木弘之 ( 2009 ) 遺伝学的手法を用いた酵母複製因子の探索—オリジナリティーとプラ
イオリティーの大切さー 実験医学27 2138 - 2140
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C. DEPARTMENT OF DEVELOPMENTAL GENETICS
C-a. Division of Developmental Genetics
C. DEPARTMENT OF DEVELOPMENTAL GENETICS
C-a. Division of Developmental Genetics
Hiroshi Shimizu
RESEARCH ACTIVITIESPUBLICATIONSPapers
1 . Shimizu, H & Namikawa, H. ( 2009 ) The body plan of the cnidarian medusa: distinct
differences in positional origins of polyp tentacles and medusa tentacles. , Evolution andDevelopment , 11 , 619 - 621
2 . 清水 裕 ( 2009 ) クラゲ形の起源と進化 , 岩波 科学 , 79 , 398 - 404
POSTER PRESENTATIONS
1 . Namikawa, H. &, Shimizu, H. 「 The polyp form and the medusa form of cnidaria: why
they look so different from each other. 」, The Evolution of Multicellularity: Insights from
Hydra and other Basal Metazoans , Tutzing , 9/14
2 . Shimizu,H. 「 Regional specification of the digestive tract of hydra 」, The Evolution ofMulticellularity: Insights from Hydra and other Basal Metazoans , Tutzing , 9/14
BOOK
1 . 清水 裕 ( 2009 ) ヒドラ 共通祖先の体制を垣間みることができる「生きた化石」 細胞工学別冊 「バイオリソース＆データベース活用術」 181 - 183
OTHERS1 . 清水裕 , 3 , Editorial Board Member of journal EvoDevo
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C. DEPARTMENT OF DEVELOPMENTAL GENETICS
C-a. Division of Developmental Genetics
C. DEPARTMENT OF DEVELOPMENTAL GENETICS
C-a. Division of Developmental Genetics
Yasushi Hiromi
RESEARCH ACTIVITIESPUBLICATIONSPapers
1 . Liu, QX., Hiramoto, M, Ueda, H., Gojobori, T., Hiromi, Y., and Hirose, S. ( 2010 )Midline governs axon pathfinding by coordinating expression of two major guidancesystems , Genes & Development , 23 , 1165 - 1170
2 . Katsuki, T.,Ailani, D.,Hiramoto, M.,Hiromi, Y. ( 2009 ) Intra-axonal Patterning: Intrinsic
Compartmentalization of the Axonal Membrane in Drosophila Neurons , Neuron , 64 ,
188 - 199
3 . 浅岡美穂 ( 2009 ) 幹細胞の局在を決めるのは何か , Surgery Frontier , 16 , 339 342
ORAL PRESENTATION
1 . 勝木健雄 脳を調べて書く 立花ゼミ見聞伝 東京大学本郷キャンパス 12/20
2 . 広海 健 器官構築の発生遺伝学〜一個の細胞は組織全体のために何が出来るか？〜
講義：分子生物学特論 東京大学・薬学系研究科 2/6
POSTER PRESENTATIONS
1 . Matsuoka, S., Asaoka, M., Hiromi, Y. 「 Gone early maintains undifferentiated state ofprimordial germ cells and regulates establishment of germ line stem cells in Drosophila
ovary. 」, The 7th Stem Cell Reserach Symposium , Tokyo , 5/15-16
2 . Asaoka, M., Matsuoka, S., Hiromi, Y. 「 The maintenance of undifferentiated state ofstem-cell precursors in Drosophila germline. 」, The 7th Stem Cell Reserach Symposium ,Tokyo , 5/15-16
3 . Matsuoka, S., Asaoka, M., Hiromi, Y. 「 gone early maintains stem-cell precursors in
undifferentiated state to establish adequate number of germline stem cells in Drosophila
ovary. 」, The 32nd Annual meeting of the Molecular Biology Society of Japan , 横浜 , 12/9
4 . 勝木健雄 「 細胞自律的な軸索膜の区画化と細胞内輸送による軸索内パターニング 」,
The 1st Conference on Intracellular Logistics , 沖縄県国頭郡 , 11/9
5 . 勝木健雄 「 軸索内パターニングのメカニズムと神経回路形成における意義 」, 頭部形成研究会 , 静岡県伊豆市 , 11/16
6 . Asaoka, M., Matsuoka, S., Hiromi Y. 「 The maintenance of undifferentiated state ofstem-cell precursors in Drosophila germline. 」, 42nd Annual Meeting for the JapaneseSociety of Developmental Biologists , Niigata , 5/28-31
7 . Ailani D., Katsuki T., Hiromi Y 「 Differential Trafficking Pathways Regulate theLocalization of Axon Guidance Receptors in Drosophila neurons 」, The 9th JapaneseDrosophila Research Conference , Kakegawa , 7/6-8
8 . 湯浅喜博・広海健 「 核内レセプター型転写因子Seven-upはグリア細胞の多様性を生み出すのか？ 」, 遺伝情報DECODE・冬のワークショップ , 新潟県湯沢町 , 1/19-21
9 . Katsuki, T., Ailani, D., Joshi, R.,Defalco, T., Hiramoto, M., Hiromi Y. 「 Intra-axonal
patterning: intrinsic compartmentalization of the axonal membrane in Drosophila neurons 」,
The 9th Japanese Drosophila Research Conference , Kakegawa , 7/6-8
10 .
Katsuki, T., Hiramoto, M.,Hiromi, Y.
「 Intra-axonal Patterning: Intrinsic
Compartmentalization of the Axonal Membrane in Drosophila Neurons 」, CDB Symposium2009 “Shape and Polarity” , Kobe , 3/23-25
11 . Joshi, R., Katsuki, T., DeFalco, T., Hiromi, Y. 「 Molecular addresses: motifs involved incompartment-specific localization of guidance receptors in Drosophila axons 」, The 9th
Japanese Drosophila Research Conference , Kakegawa , 7/6-8
12 . Matsuoka, S., Asaoka, M., Hiromi, Y. 「 Gone early maintains undifferentiated state ofprimordial germ cells and regulates establishment of germline stem cells 」, 42nd Annual
Meeting for the Japanese Society off Developmental Biologists , Nigata , 5/28-31
OTHERS
1 . Y. Hiromi ,Differentiation.

3 ,Dr. Hiromi served as an editor for Development, Growth andbackAnnual Report 2009

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C. DEPARTMENT OF DEVELOPMENTAL GENETICS
C-b. Division of Neurogenetics
C. DEPARTMENT OF DEVELOPMENTAL GENETICS
C-b. Division of Neurogenetics
Takuji Iwasato
RESEARCH ACTIVITIESPUBLICATIONSPapers
1 . Takeuchi,S., Yamaki,N., Iwasato,T., Negishi,M., Katoh,H. ( 2009 ) Beta2-chimaerinbinds to EphA receptors and regulates cell migration. , FEBS Lett. , 583 , 1237 - 1242
2 . Singer,P., Yee,B.K., Feldon,J., Iwasato,T., Itohara,S., Grampp,T., Prenosil,G., Benke,D.,
Mohler,H., Boison,D. ( 2009 ) Altered mnemonic functions and resistance to NMETHYL-dAspartate receptor antagonism by forebrain conditional knockout of glycine transporter 1. ,Neuroscience , 161 , 635 - 654
3 . 岩里琢治 ( 2009 ) 中枢神経回路の活動依存的精緻化 , 生物の科学 遺伝 , 63 , 79 85
ORAL PRESENTATION
1 . 岩里琢治 ”変異マウス”が解き明かす”脳回路”の発達と”遺伝子”の働き 生物学持論XI
名古屋大学・理学部 6/2
2 . 岩里琢治 哺乳類中枢神経系における回路発達―”樽”と”ミッフィー”の遺伝学― 名古屋
大学セミナー 名古屋大学 6/3
3 . 岩里琢治 ”変異マウス”が解き明かす”脳回路”の発達と”遺伝子”の働き 薬学実習ⅢD
慶應大学・薬学部 9/2
4 . 岩里琢治 バレル形成の遺伝学 医学共通講義Ⅱ 東京大学大学院・医学部 11/9
5 . 岩里琢治 ”変異マウス”が解き明かす”脳回路”の発達と”遺伝子”の働き 基礎生物学Ⅱ
埼玉大学 1/22
6 . 岩里琢治 ”変異マウス”が解き明かす”脳回路”の発達と”遺伝子”の働き 基礎生物学Ⅱ
埼玉大学 7/22
POSTER PRESENTATIONS
1 . 山本亘彦,岩里琢治 「 シナプス回路形成と維持-ショウジョウバエから哺乳類まで 」, 第32回日本神経科学大会 , 名古屋市 , 9/16
2 . 岩里琢治 「 マウス体性感覚系にみる神経回路の生後発達機構 」, 頭部形成研究会 , 修
善寺 , 11/16
EDUCATION
1 . 岩里琢治,山本亘彦 シナプス回路形成と維持-ショウジョウバエから哺乳類まで 第32回日本神経科学大会 名古屋 9/16

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C. DEPARTMENT OF DEVELOPMENTAL GENETICS
C-c. Division of Molecular and Developmental Biology
C. DEPARTMENT OF DEVELOPMENTAL GENETICS
C-c. Division of Molecular and Developmental Biology
Koichi Kawakami
RESEARCH ACTIVITIESPUBLICATIONSPapers
1 . Komisarczuk, A.Z., Kawakami, K., Becker, T.S. ( 2009 ) Cis-regulation andchromosomal rearrangement of the fgf8 locus after the teleost/tetrapod split. ,Developmental Biology , 336(2) , 301 - 312
2 . Kawakami, K. ( 2009 ) The transgensis and gene and enhancer trap methods inzebrafish by using the Tol2 transposable element. , Essential zebrafish methods:
genetics and genomics , , 153 - 173
3 . Sugiyama, M., Sakaue-Sawano, A., Iimura, T., Fukami, K., Kitaguchi, T., Kawakami, K.,
Okamoto, H., Higashijima, S.-I., Miyawaki, A. ( 2009 ) Illuminating cell-cycle progression in
the developing zebrafish embryo , Proc. Natl. Acad. Sci. USA , 106 , 20812 - 20817
4 . Appelbaum, L., Wang, G.X., Maro, G.S., Mori, R., Tovin, A., Marin, W., Yokogawa, T.,
Kawakami, K., Smith, S.J., Gothilf, Y., Mignot, E., Mourrain, P. ( 2009 ) Sleep-wakeregulation and hypocretin-melatonin interaction in zebrafish , Proc. Natl. Acad. Sci. USA ,106 , 21942 - 21947
5 . Kim, DJ., Seok, SH., Baek, MW., Lee, HY., Na, YR., Park, SH., Lee, HK., Dutta, NK.,
Kawakami, K., Park, JH. ( 2009 ) Estrogen-responsive transient expression assay using a
brain aromatase-based reporter gene in zebrafish (Danio rerio). , Comparative medicine, 59(5) , 416 - 423
6 . Picker, A., Cavodeassi, F., Machate, A., Bernauer, S., Hans, S., Abe, G., Kawakami, K.,
Wilson, SW., Brand, M. ( 2009 ) Dynamic coupling of pattern formation andmorphogenesis in the developing vertebrate retina. , PLoS biology , 7(10) , 1000214 - 0
7 . Suster, ML., Sumiyama, K., Kawakami, K. ( 2009 ) Transposon-mediated BAC
transgenesis in zebrafish and mice. , BMC Genomics , 10 , 477 - 0
8 . Asakawa, K., Kawakami, K. ( 2009 ) The Tol2-mediated Gal4-UAS method for geneand enhancer trapping in zebrafish. , Methods , 49(3) , 275 - 281
9 . Kim, DJ., Seok, SH., Baek, MW., Lee, HY., Na, YR., Park, SH., Lee, HK., Dutta, NK.,
Kawakami, K., Park, JH. ( 2009 ) Developmental toxicity and brain aromatase induction byhigh genistein concentrations in zebrafish embryos. , Toxicology mechanisms andmethods , 19(3) , 251 - 256
10 . Mejia-Pous, C., Viñuelas, J., Faure, C., Koszela, J., Kawakami, K., Takahashi, Y.,
Gandrillon, O. ( 2009 ) A combination of transposable elements and magnetic cell sorting
provides a very efficient transgenesis system for chicken primary erythroid progenitors. ,BMC biotechnology , 9 , 81 - 0
11 . Kim, DJ., Seok SH., Baek, MW., Lee, HY., Na, YR., Park, SH., Lee, HK., Dutta, NK.,
Kawakami, K., Park, JH. ( 2009 ) Benomyl induction of brain aromatase and toxic effects

in the zebrafish embryo. , Journal of Applied Toxicology , 29 , 289 - 294
12 . Suster, M.L., Kikuta, H., Urasaki, A., Asakawa, K., Kawakami, K. ( 2009 )Transgenesis in zebrafish with the Tol2 transposon system , Methods in Molecular
Biology , 561 , 41 - 63
13 . Koide, T., Miyasaka, N., Morimoto, K., Asakawa, K., Urasaki, A., Kawakami, K.,
Yoshihara, Y. ( 2009 ) Olfactory neural circuitry for attraction to amino acids revealed bytransposon-mediated gene trap approach in zebrafish. , Proc. Natl. Acad. Sci. USA , 106, 9884 - 9889
14 . 浦崎明宏, 浅川和秀, 川上浩一 ( 2009 ) メダカトランスポゾンTol2が開く 新しいゼブラフ
ィッシュ研究 , 細胞工学 , 28 , 586 - 591
15 . Kitaguchi, T., Kawakami, K., Kawahara, A. ( 2009 ) Transcriptional regulation of amyeloid-lineage specific gene lysozyme C during zebrafish myelopoiesis. , Mechanismsof Devlopment , 126 , 314 - 323
16 . Urasaki, A., Kawakami, K. ( 2009 ) Analysis of genes and genome by the Tol2mediated gene and enhancer trap methods , Methods in Molecular Biology , 546 , 85 102
17 . Kikuta, H., Kawakami, K. ( 2009 ) Transient and stable transgenesis using Tol2transposon vectors. , Methods in Molecular Biology , 546 , 69 - 84
18 . Esaki, M., Hoshijima, K., Nakamura, N., Munakata, K., Tanaka, M., Ookata, K.,
Asakawa, K., Kawakami, K., Wang, W., Weinberg, ES., Hirose, S. ( 2009 ) Mechanism ofdevelopment of ionocytes rich in vacuolar-type H(+)-ATPase in the skin of zebrafish larvae.
, Developmental Biology , 329 , 116 - 129
19 . Suster, M.L., Kania, A., Liao, M., Asakawa, K., Charron, F., Kawakami, K., Drapeau,
P. ( 2008 ) A novel conserved evx1 enhancer links spinal interneuron morphology and cisregulation from fish to mammals. , Developmental Biology , 325 , 422 - 433
20 . Faucherre, A., Pujol-Martí, J., Kawakami, K., López-Schier, H. ( 2008 ) Afferent
neurons of the zebrafish lateral line are strict selectors of hair-cell orientation. , PLoS ONE.
, 4 , 4477 - 0
21 . Chen, YC., Cheng, CH., Chen, GD., Hung, CC., Yang, CH., Hwang, SP., Kawakami,K., Wu, BK., and Huang, CJ. ( 2008 ) Recapitulation of zebrafish sncga expression pattern
and labeling the habenular complex in transgenic zebrafish using green fluorescent protein
reporter gene. , Developmental Dynamics , 238 , 746 - 754
22 . Santoriello C, Deflorian G, Pezzimenti F, Kawakami K, Lanfrancone L, d'Adda diFagagna F, and Mione M. ( 2008 ) Expression of H-RASV12 in a zebrafish model of
Costello syndrome causes cellular senescence in adult proliferating cells. , Diseasemodels & mechanisms , 2 , 56 - 67
ORAL PRESENTATION
1 . 川上浩一 脊椎動物におけるトランスポゾンテクノロジーとゼブラフィッシュ遺伝学への応用
癌研究会癌研究所セミナー 癌研究会癌研究所 9/7
2 . 川上浩一 脊椎動物におけるトランスポゾンテクノロジーとゼブラフィッシュ神経回路機能研
究 九州大学生体防御医学研究所セミナー 九州大学生体防御医学研究所 6/26
POSTER PRESENTATIONS
1 . Yagita, K., Horie, K., Shigeyoshi, Y., Kawakami, K., Takeda, J., Uchiyama, Y., andShimada, S. 「 Development of Circadian Clock Oscillator During the Mouse ES cell
Differentiation in vitro 」, 第50回日本組織細胞化学会総会 , 大津 , 9/26-27
2 . Kotani, T., Iemura, S., Natsume, T., Kawakami, K., and Yamashita, M. 「 Mys protein
antagonizes Hedgehog signaling through activation of PKA during embryonic development」, 16th International Society of Developmental Biologists Congress , Edinburgh, Scotland, 9/9-10
3 . Picker, A., Cavodeassi, F., Machate, A., Bernauer, S., Hans, S., Abe, G., Kawakami, K.,
Wilson, S., and Brand, M. 「 Dynamic coupling of pattern formation and morphogenesis in
the developing vertebrate retina 」, 16th International Society of Developmental Biologists
Congress , Edinburgh, Scotland , 9/9-10

4 . Santoriello, C., Deflorian, G., Pezzimenti, F.,Kawakami, K., Lanfrancone, L., d’Adda Di
Fagagna, F., and Mione, M. 「 Expression of H-RASV12 in a zebrafish model of Costellosyndrome causes cellular senescence in adult proliferating cells 」, 16th International
Society of Developmental Biologists Congress , Edinburgh, Scotland , 9/9-10
5 . Kawakami, K. 「 Genetic methods using the Tol2 transposable element in zebrafish 」,
International Symposium on Marine Genomics 2009 , Naha, Okinawa , 12/15-18
6 . Asakawa, K., Abe, G., Takakubo, H., Ito, A., Urasaki, A., Kikuta, H., Suster, M.L., Muto,
A., Lal, P., Kawakami, K. 「 Role of the hindbrain in embyonic motility and location 」, 第32回日本分子生物学会年会 , 横浜 , 12/9〜12
7 . Morita, R., Yamamoto, M., Mizoguchi, T., Isoda, M., Matsumoto, K., Yonemura, S.,
Kawakami, K., Itoh, M. 「 Jagged-Notch signaling regulates patterning activity and structuralrole of the Notochord through control of cell differentiation 」, 第32回日本分子生物学会年会, 横浜 , 12/9〜12
8 . Yano, T., Abe, G., Kawakami, K., Yokoyama, H., Tamura, K. 「 Mechanism of pectoralfin development in zebrafish using prx1 limb-specific enhancer activity. 」, 第32回日本分子生物学会年会 , 横浜 , 12/9〜12
9 . Tanino, S., Abe, G., Kawakami, K., Nakamura, H., Funahashi, J. 「 Gene trap revealed aroll of Sox5 in the morphogenesis of the semicircular canal 」, 第32回日本分子生物学会年
会 , 横浜 , 12/9〜12
10 . Takeuchi, M., Kaneko, H., Nishikawa, K., Kawakami, K., Yamamoto, M., Kobayashi, M.
「 An easy and effective approach to rescue zebrafish mutant phenotypes via transienttransgenesis using Tol2 constructs 」, 第32回日本分子生物学会年会 , 横浜 , 12/9〜12
11 . Agetsuma, M., Aizawa, H., Aoki, T., Takahoko, M., Nakayama, R., Shiraki, T., Goto, M.,
Kawakami, K., Higashijima, S., Okamoto, H. 「 Genetic inactivation of the habenulointerpeduncular projection enhances the conditioned fear response in zebrafish 」, 第32回
日本分子生物学会年会 , 横浜 , 12/9〜1212 . Yoshida, J., Kokubu, C., Kawakami, K., Takeda, J., Horie, K. 「 Insertionalmutagenesis of the mouse ES cell genome with the Tol2 transposon 」, 第32回日本分子生物学会年会 , 横浜 , 12/9〜12
13 . 川上浩一 「 光るゼブラフィッシュリソース 」, NBRPシンポジウム「ＮＢＲＰが提供するミュータントリソース」 , 横浜 , 12/9
14 . Agetsuma, M., Aizawa, H., Aoki, T., Takahoko, M., Nakayama, R., Shiraki, T., Goto, M.,
Kawakami, K., Higashijima, S. 「 Functional analysis of the habenula in control of fear 」, 6th
European Zebrafish Genetics and Development Meeting , Rome , 7/15-19
15 . 浦崎明宏,川上浩一 「 Tol2を用いたゼブラフィッシュ遺伝子の網羅的破壊 」, 日本遺伝学会第81回大会 , 松本 , 9/16-18
16 . Suster, M.L.,Kawakami, K. 「 Botulinum Neurotoxin transgenic zebrafish for dissecting
neuronal circuits in vivo and creating novel variants for neurotherapeutics 」, 46th Congressof the European Societies of Toxicology , Dresden, Germany , 9/13-16
17 . Kawakami, K. 「 Tol2-mediated transgenesis in zebrafish and mice 」, Conference on
Genome Engineering , Minneapolis, Minnesota , 6/25-27
18 . 武藤彩, 中井淳一, 川上浩一 「 ゼブラフィッシュ運動系における機能的神経回路の可視化 」, 第15回小型魚類研究会 , 名古屋 , 9/12-13
19 . 浅川和秀, 阿部玄武, 高久保瞳, 伊藤安希, 浦崎明宏, 菊田寛, Suster, M.L., 武藤彩, Lal,P., 川上浩一 「 触覚刺激に対する逃避行動の発達における後脳の役割 」, 第15回小型魚類研究会 , 名古屋 , 9/12-13
20 . 小出哲也, 宮坂信彦, 川上浩一, 吉原良浩 「 アミノ酸への誘因行動を介在するゼブラフィ
ッシュ嗅覚神経回路の遺伝学的解析 」, 第15回小型魚類研究会 , 名古屋 , 9/12-13
21 . 竹内未紀, 金子寛, 西川恵三, 川上浩一, 山本雅之, 小林麻己人 「 Tol2システムを利用した一過性レスキュー解析 」, 第15回小型魚類研究会 , 名古屋 , 9/12-13
22 . 阿部玄武, 高久保瞳, 浅川和秀, 菊田寛, 武藤彩, Suster, M.L., 浦崎明宏, 川上浩一 「IRESを用いたTol2トランスポゾンによる遺伝子トラップ法の開発 」, 第15回小型魚類研究会 ,名古屋 , 9/12-13
23 . 池永隆徳, Urban, J.M., Gebhart, N., 川上浩一, 小野富三人 「 ゼブラフィッシュ脊髄でのpax8遺伝子の発現パターンと回路形成における役割 」, 第15回小型魚類研究会 , 名古屋, 9/12-13
24 . 揚妻正和, 相澤秀則, 青木田鶴, 鷹矛美賀子, 中山涼子, 白木利幸, 後藤翠, 川上浩一, 東島眞一, 岡本仁 「 手綱核・脚間核路の遺伝学的破壊はゼブラフィッシュの恐怖反応を昂進させる 」, 第32回日本神経科学大会 , 名古屋 , 9/16-18
25 . 武藤彩, 中井淳一, 川上浩一 「 カルシウムイメージング法を用いたゼブラフィッシュ機能的神経回路の可視化 」, 第32回日本神経科学大会 , 名古屋 , 9/16-18
26 . 小出哲也, 宮坂信彦, 川上浩一, 吉原良浩 「 アミノ酸への誘因行動を司るゼブラフィッシ
ュ嗅覚神経回路の遺伝学的解析 」, 第32回日本神経科学大会 , 名古屋 , 9/16-18
27 . 吉田綾子, 山口良文, 野々村恵子, 川上浩一, 高橋淑子, 三浦正幸 「 子宮内穿孔法とTol2トランスポゾンシステムを用いてグリア細胞特異的に遺伝子を発現させる方法の開発 」,
第32回日本神経科学大会 , 名古屋 , 9/16-18
28 . 喜多善亮, 川上浩一, 高橋淑子 「 小脳を構成するニューロンとグリアの発生ー子宮内電気穿孔法を用いた網羅的解析ー 」, 第32回日本神経科学大会 , 名古屋 , 9/16-18
29 . 矢野十織, 阿部玄武, 川上浩一, 横山仁, 田村宏治 「 Apical fold morphogenesis inzebrafish fin; differences from tetrapod limb development 」, 16th International Society ofDevelopmental Biologists Congress , Edinburgh, Scotland , 9/9-10
30 . Han, HW., Chen, YC., Wu, BK., Chu, CY., Cheng, CH., Chen, GD, Hwang, SP. L.,
Kawakami, K., Huang, CJ. 「 Transgenic zebrafish Tg(Nogo-B:GFP) line recapitulates theNogo-B expression pattern in diverse tissues including the liver and intestine 」, 6th
European Zebrafish Genetics and Development Meeting , Rome , 7/15-19
31 . Appelbaum, L., Wang, G., Maro, G., Marin, W., Yokogawa, T., Kawakami, K., Mignot,
E., Mourrain, P. 「 Hypocretin interacts with melatonin in regulating sleep in zebrafish 」, 6th
European Zebrafish Genetics and Development Meeting , Rome , 7/15-19
32 . Cheng, C. H., Chen, Y-C., Chen, G-D., Hung, C-C., Kawakami, K., Huang, F-L., Huang,
C-J. 「 A novel zebrafish cyclin dx gene: expression profile, requirement for the developmentof primordium motor neuron, pmn and characterization of its promoter region 」, 6th
European Zebrafish Genetics and Development Meeting , Rome , 7/15-19
33 . Ono, F., Ikenaga, T., Urban, J., Gebhart, N., Kawakami, K. 「 Formation of spinal
network dependent on domain-specific Pax genes 」, 6th European Zebrafish Genetics andDevelopment Meeting , Rome , 7/15-19
34 . Urasaki, A., Isogai, S., Kimura, E., Hitomi, J., Kawakami, K. 「 The gene trap approachreveals involvement of mekk3b in the functional blood vessel formation 」, 6th European
Zebrafish Genetics and Development Meeting , Rome , 7/15-19
35 . Santoriello, C., Deflorian, G., Pezzimenti, F., Kawakami, K., Lanfrancone, L., ďAdda diFagagna, F., Mione, M. 「 Expression of H-RASV12 in a zebrafish model of Costellosyndrome causes cellular senescence in adult proliferating cells 」, 6th European Zebrafish
Genetics and Development Meeting , Rome , 7/15-19
36 . Okamoto, H., Agetsuma, M., Aizawa, H., Aoki, T., Takahoko, M., Nakayama, R.,
Shiraki, T., Goto, M., Kawakami, K., Higashijima, S. 「 Functional analysis of the habenula
in control of fear 」, The 4th Asia-Oceania Zebrafish Meeting , Jeju, Korea , 8/31-9/2
37 . Kawakami, K. 「 Transposon-mediated gene trapping, enhancer trapping andinsertional mutagenesis 」, The 4th Asia-Oceania Zebrafish Meeting , Jeju, Korea , 8/319/2
38 . 矢野十織,阿部玄武,川上浩一,横山仁,田村宏治 「 ゼブラフィッシュ胸鰭末端上皮の形態
形成 」, 第６回 東北大学バイオサイエンスシンポジウム , 仙台 , 6/16
39 . 川上浩一 「 zTrap: zebrafish gene trap and enhancer trap database 」, データベースが拓くこれからのライフサイエンス , 東京 , 6/12
40 . 川上浩一,平田晋三 「 生命の不思議を解き明かす光るゼブラフィッシュ 」, ゲノムひろば
2009 in アキバ・ゲノム研究勢ぞろい , 東京 , 8/1-2
41 . 川上浩一 「 光るゼブラフィッシュがひらく新しいゲノム科学 」, ゲノム研究最前線 −ゲノム
科学がもたらす生命の新たな理解− , 東京 , 2/25
42 . Abe, G., Kotani, T., Kishimoto, Y., Kawakami, K. 「 The zebrafish cdc73 is essential forembryogenesis and expression of fgf24 in pectoral fin development 」, 42nd Annual
Meeting for the Japanese Society of Developmental Biologists , 新潟 , 5/28-31
43 . Lal, P., Kawakami, K. 「 Characterization of gene trap and enhancer trap transgenic
zebrafish lines that express Gal4 in specific region of brain in adult stage 」, 42nd Annual
Meeting for the Japanese Society of Developmental Biologists , 新潟 , 5/28-31
44 . Yano, T., Abe, G., Kawakami, K., Yokoyama, H., Tamura, K. 「 Apical foldmorphogenesis of pectoral fin in zebrafish 」, 42nd Annual Meeting for the JapaneseSociety of Developmental Biologists , 新潟 , 5/28-31
45 . Yoshida, A., Yamaguchi, Y., Nonomura, K., Kawakami, K., Takahashi, Y., Miura, M. 「An effective and convenient method to express transgene by the combination of in utero
electroporation and the Tol2 transposon system; inducible or cell-type specific expression
in glia 」, 42nd Annual Meeting for the Japanese Society of Developmental Biologists , 新
潟 , 5/28-31
46 . Agetsuma, M., Aizawa, H., Aoki, T., Takahoko, M., Nakayama, R., Shiraki, T., Goto, M.,
Kawakami, K., Higashijima, S., Okamoto, H. 「 Genetic inactivation of the asymmetrichabenulo-interpeduncular projection enhances the conditioned fear response in zebrafish 」,
The 2009 meeting on Synapses: from molecules to circuits & behavior, Cold Spring Harbor
Laboratory , New York , 4/14-18
47 . 浦崎明宏, 川上浩一 「 Tol2トランスポゾンのin vivo転移 」, トランスポゾンに基づくゲノム・遺伝子研究 , 三島 , 2/26-27
48 . 武藤彩, 川上浩一 「 ゼブラフィッシュの遺伝子トラップ・エンハンサートラップ：機能的神経回路の可視化 」, 遺伝子改変ゼブラフィッシュを用いた生体内イメージングと脊椎動物高次生
命現象の遺伝学的研究 , 三島 , 3/18-19
49 . Kawakami, K. 「 Transposon-mediated insertional mutagenesis: an overview 」,
Zebrafish Knockout Project: Organization & Strategy Meeting , Cambridge, UK , 3/7-9
50 . Kawakami, K. 「 Recent advances in the Tol2 transposon technology in zebrafish 」,
3rd Strategic Conference of Zebrafish Investigators , Asilomar, USA , 1/24-28
51 . Yamamoto, M., Isoda, M., Matsumoto, K., Yonemura, S., Kawakami, K., Itoh, M. 「Jagged-Notch signaling regulates notochord morphogenesis in zebrafish 」, 3rd Strategic
Conference of Zebrafish Investigators , Asilomar, USA , 1/24-28
EDUCATION
1 . 川上浩一,日比正彦 脊椎動物器官形成研究の新展開 第32回日本分子生物学会ワークショップ 横浜 12/11
2 . 川上浩一 トランスポゾンに基づくゲノム・遺伝子研究 国立遺伝学研究所研究会 三島2/26-27
3 . 川上浩一 遺伝子改変ゼブラフィッシュを用いた生体内イメージングと脊椎動物高次生命
現象の遺伝学的研究 国立遺伝学研究所研究会 三島 3/18-19
4 . 川上浩一,浦崎明宏 モデル動物におけるトランスポゾン 日本遺伝学会第81回大会ワー
クショップ 松本 9/16-18
BOOK
1 . Lieschke, G.J., Oates, A.C., Kawakami, K. ( 2009 ) Zebrafish: methods and protocols
Zebrafish: methods and protocols 0 - 0
PATENT
1 . 特願2009-211821 , ボツリヌス毒素の生産測定システム , 川上浩一、サスター、マキシミ
リアーノ , 大学共同利用機関法人情報・システム研究機構
2 . 特許第4364474号 , 哺乳動物において機能的なトランスポゾン , 川上浩一、野田哲生 ,情報・システム研究機構
3 . 1484395 , Transposon transfer factor functioned in mammal , 川上浩一、野田哲生 , 情報・システム研究機構
OTHERS
1 . Koichi Kawakami , 3 , Editorial Board of Zebrafish
2 . Koichi Kawakami , 3 , Editorial Board of Mobile DNA
backAnnual Report 2009

No. 60back

D. DEPARTMENT OF POPULATION GENETICS
D-a. Division of Population Genetics
D. DEPARTMENT OF POPULATION GENETICS
D-a. Division of Population Genetics
Naruya Saitou
RESEARCH ACTIVITIESPUBLICATIONSPapers
1 . Sagai, T., Amano, T., Tamura, M., Mizushina, Y., Sumiyama, K., and Shiroishi, T. ( 2008
) A cluster of three long-range enhancers directs regional Shh expression in the epithelial
linings , Development , 136 , 1665 - 1674
2 . Shimada,M.K., Hayakawa,S., Fujita,S., Sugiyama,Y., Saitou,N. ( 2009 ) Skewed
Matrilineal Genetic Composition in a Small Wild Chimpanzee Community , Folia
Primatologica , 80 , 19 - 32
3 . Takahashi,M., Krukov,K., Saitou,N. ( 2009 ) Estimation of bacterial species phylogeny
through oligonucleotide frequency distances , Genomics , 93 , 525 - 533
4 . Takeshima,S., Sarai,Y., Saitou,N., Aida, Y. ( 2009 ) MHC class II DR classification
based on antigen-binding groove natural selection , Biochemical and BiophysicalResearch Communications , 385 , 137 - 142
5 . Hattori,E., Nakajima,M., Yamada,K., Iwayama,Y., Toyota,T., Saitou,N., Yoshikawa,T. (2009 ) Variable number of tandem repeat polymorphisms of DRD4: re-evaluation of
selection hypothesis and analysis of association with schizophrenia , European Journalof Human Genetics , 17 , 793 - 801
6 . Kitano,T., Noda,R., Takenaka,O., Saitou, N. ( 2009 ) Relic of ancient recombinations ingibbon ABO blood group genes deciphered through phylogenetic network analysis ,Molecular Phylogenetics and Evolution , 51 , 465 - 471
7 . Yuasa,I., Umetsu,K., Nishimukai,H., Fukumori,Y., Harihara,S., Saitou,N., Jin,F.,
Chattopadhyay,P.K., Henke,L., Henke,J. ( 2009 ) HERC1 polymorphisms: populationspecific variations in haplotype composition , Cell Biochemistry and Function , 27 ,402 - 405
8 . Yuasa,I., Irizawa,Y., Nishimukai,H., Fukumori,Y., Umetsu,K., Nakayashiki,N., Saitou,N.,
Henke,L. and Henke,J. ( 2009 ) A hypervariable STR polymorphism in the complement
factor I (CFI) gene: Asian-specific alleles , International Journal of Legal Medicine , inpress , 0 - 0
9 . 斎藤成也 ( 2009 ) 中立進化論が生物進化の基本になるまで. 特集『木村資生が拓いた分子進化学の40年』 , 総研大ジャーナル , 15 , 3 - 5
10 . 斎藤成也 ( 2009 ) 霊長類のゲノム解読と分子系統 , 霊長類研究 Primate Res. , 24 ,213 - 220
11 . 斎藤成也，鈴木留美子，河合洋介，石田貴文 ( 2009 ) 霊長類の種内変異を解析するためのPCRプライマーデータベースPrim-Primの開発とその応用 , DNA多型 , 17 , 63 - 65
12 . 斎藤成也 ( 2009 ) 集団遺伝学を中心とする遺伝子進化の研究 , 生物の科学 遺伝 ,63 , 44 - 50

13 . 斎藤成也 ( 2009 ) ヒトゲノム研究の新しい地平 , Anthropological Science , 117 , 1-914 . Suster, ML., Sumiyama, K., Kawakami, K. ( 2009 ) Transposon-mediated BAC
transgenesis in zebrafish and mice. , BMC Genomics , 10 , 477 - 0
ORAL PRESENTATION
1 . 斎藤 成也 分子進化学 講義 山形大学・医学部 1/22
2 . 斎藤 成也 分子進化学 講義 東京大学 6/17,24,7/1,8
3 . 斎藤 成也 分子進化学 講義 関西学院大学 8/27,28
4 . 斎藤 成也 ゲノム生物学 講義 総合研究大学院大学 11/9, 16
5 . 斎藤 成也 分子免疫学 講義 長崎大学・医学部 12/18
6 . 斎藤成也 文化文明論〜DNAから宗教まで〜 行政研修 人事院入間研修所・入間市
8/22
7 . 斎藤成也 遺伝子から見た日本列島人のルーツ 小泉信三記念講座 慶応義塾大学
4/28
8 . 斎藤成也 ゲノムから読み解く日本人の起源 学術俯瞰講義 東京大学駒場キャンパス
5/1
9 . 斎藤成也 ゲノムと進化-人類への道 学術俯瞰講義 東京大学駒場キャンパス 4/22
10 . 斎藤成也 人間とウシの古代ＤＮＡ研究のために インダスプロジェクト、コアメンバー会
議 総合地球環境学研究所 10/14
11 . Sumiyama, K. How to extract sequences from DDBJ Special Hands-on Seminar“How to Master Bioinformatics of Hepatitis Viruses Using International Databases”
International Medical Center, Shinjuku, Japan 11/23
POSTER PRESENTATIONS
1 . Matsunami M., Sumiyama K., Saitou N. 「 Evolution of conserved non-coding
sequences within Hox clusters through the two-round whole duplications revealed byphylogenetic footprinting analysis 」, SMBE Annual Meeting 2009 , Iowa City , 6/5
2 . Matsunami M. 「 Phylogenetic footprinting reveals evolution of conserved non-coding
region within Hox clusters through the two rounds whole genome duplication 」, 第1回生命情報科学若手の会 , 三島 , 4/25
3 . 松波雅俊, 隅山健太, 斎藤成也 「 系統フットプリンティングを用いた脊椎動物Hoxクラスタ
ーの非コード保存領域の進化的解析 」, 第11回日本進化学会年会 , 札幌市 , 9/2-4
4 . Matsunami M., Saitou N. 「 Searching for conserved non-coding elements derived fromthe two-round whole duplications 」, 2009年度総研大生命科学科合同セミナー , 掛川市 ,11/5-65 . 鈴木留美子、江澤潔、斎藤成也 「 タンパク質コーディング領域内高度保存領域の同定 」,
第１１回日本進化学会大会 , 札幌市 , 9/2-4
6 . Kryukov, K., Saitou, N. 「 MISHIMA - a new heuristic method of multiple sequencealignment 」, Moscow Conference on Computational Molecular Biology , Moscow, Russia ,7/20-23
7 . Takahashi, M., Saitou, N. 「 Identification of non-coding sequences conserved
specifically in primates 」, ESF research conference, Complex systems and changes:
darwin and evolution -nature-culture interfaces , San Feliu, Spain , 7/13
8 . Sato,Y., Hashiguchi,Y., Nishida,M. 「 Combination of genome data and systems biology
approach: Evolution of multiple phosphodiesterases in stickleback involved in olfactorytransduction system 」, The International Symposium on Complex Systems Biology , Tokyo, 9/29-10/1
9 . 佐藤行人，橋口康之，西田睦 「 嗅覚シグナル伝達経路に関与するフォスフォジエステラー
ゼ１Ｃ遺伝子の多重化がもたらす効果についてのパスウェイシミュレーションを用いた検討 」,
日本遺伝学会 第81回大会 , 松本市 , 9/17
10 . 佐藤行人，橋口康之，西田睦． 「 Evolution of multiple phosphodiesterase isoforms instickleback involved in olfactory signal transduction pathway 」, 生命情報科学若手の会・第１回研究会 , 三島市 , 4/25
11 . Jinam,T., Phipps,M., Saitou, N. 「 Patterns of genetic variation in indigenous Malaysianpopulations based on genome-wide SNP markers 」, 第１１回日本進化学会大会 , 札幌市 ,9/2-4
12 . Jinam,T., Phipps,M., Saitou, N. 「 Population differentiation and genetic diversity inSoutheast Asian populations 」, 第 63回日本人類学会大会 , 東京 , 10/3-4
13 . Jinam,T., Saitou,N. 「 Relationships between Southeast Asian human populations
based on genome-wide SNP markers 」, 2009年度総研大生命科学合同セミナー , 掛川市 ,11/5-6
14 . Saitou,N. 「 Evolution of protein non-coding DNA region in vertebrates 」, 8th JapanKorea-China Bioinformatics Symposium , Kyoto , 2/28
15 . Saitou, N. 「 Evolution of vertebrate-specific, primate-specific and mammalian-specifichighly conserved non-coding genomic region 」, Japan-Germany Colloquium 2009
"Evolutionary Genomics" , Bonn , 3/10
16 . Saitou,N., Ezawa,K., Ikeo,K., Gojobori,T.
「 Evolutionary Pattern of Gene
Homogenization between Primate-Specific Paralogs after Human and Macaque Speciation」, SMBE Annual Meeting 2009 , Iowa City , 6/5
17 . 斎藤成也 「 遺伝子から見る人類進化 」, 日本遺伝学会第８１回大会公開市民講座 , 松
本市 , 9/16
18 . 斎藤成也 「 量的形質と離散形質の研究史 」, 日本遺伝学会第８１回大会 , 松本市 ,9/17
19 . 斎藤成也 「 人類の視点から生物をながめる 」, サイエンスアゴラ2009「統合生物学〜生物をまとめて調べると見えてくる世界」 , 東京 , 11/2
20 . 斎藤成也 「 自然淘汰論から中立進化論へ 」, 日本人類学会公開講演会「ダーウィンと人類進化」 , 東京 , 11/3
21 . 斎藤成也 「 系統ネットワークの理論と応用 」, 農林交流センターワークショップ , つくば
市 , 11/4
22 . Saitou, N. 「 MISHIMA - Method for Inferring Sequence History In terms of Multiple
Alignment 」, PICB Minisymposium on Current Challenges in Computational Biology ,Shanghai , 9/12
23 . Saitou,N. 「 Evolutionary patterns of gene homogenization between primate-specificparalogs after human and macaque speciation 」, PICB Workshop on Cpmparative
Sequence Analysis 2009 , Shanghai , 10/22
24 . 斎藤成也 「 All biology aspire to evolution 」, 2009年度総研大生命科学合同セミナー ,
掛川市 , 11/5
25 . Sumiyama, K., Ruddle, FH. 「 Cis-element evolution of the Dlx genes as an underlying
mechanism in toolkit gene co-option in vertebrate appendages 」, The International Darwin
Bicentennial Symposium , Sapporo , 9/3
26 . 隅山 健太 「 ヒト特異的加速進化保存非コード配列HACNS1で正淘汰進化は起きたのか？ 」, 第63回日本人類学会大会 , 東京 , 10/3-4
27 . 隅山 健太 「 脊椎動物におけるＤｌｘ遺伝子エンハンサーの分子進化 」, 第１１回日本進化学会大会 , 札幌 , 9/2-9/4
28 . 隅山 健太 「 マウスDlx3遺伝子転写調節機構研究へのTol2システム応用の試み 」, トラ
ンスポゾンに基づくゲノム・遺伝子研究 , 三島 , 2/26-27
BOOK
1 . 斎藤成也 ( 2009 ) 自然淘汰論から中立進化論へ〜進化学のパラダイム転換〜 自然淘汰論から中立進化論へ〜進化学のパラダイム転換〜 0 - 0
2 . 斎藤成也、海部陽介、米田穣、隅山健太 ( 2009 ) 絵でわかる人類の進化 絵でわかる
人類の進化 0 - 0
3 . 斎藤成也 ( 2009 ) 進化論をめぐって シリーズ朝倉「言語の可能性」 10 - 38
4 . 斎藤成也，佐々木閑 ( 2009 ) 生物学者と仏教学者 七つの対論 生物学者と仏教学者
七つの対論 0 - 0

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No. 60back

D. DEPARTMENT OF POPULATION GENETICS
D-a. Division of Population Genetics
D. DEPARTMENT OF POPULATION GENETICS
D-a. Division of Population Genetics
Toshiyuki Takano
RESEARCH ACTIVITIESPUBLICATIONSPapers
1 . Takahashi, K.R. ( 2009 ) Coalescent under the evolution of coadaptation. , Molecular
Ecology , 18 , 5018 - 5029
2 . Tanaka, K.M., Takahashi, K.R. and Takano-Shimizu, T ( 2009 ) Enhanced fixation andpreservation of a newly arisen duplicate gene by masking deleterious loss-of-function
mutation. , Genetics Research , 91 , 267 - 280
3 . Tatsuta, T., Takano-shimizu, T. ( 2009 ) High genetic differentiation between an Africanand a non-African strain of Drosophila simulans revealed by segregation distoration andreduced crossover frequency , Genetica , 137 , 165 - 171
4 . Fujikawa, K., Takahashi, A., Nishimura, A., Itoh, M., Takano-Shimizu, T. and Ozaki, M. (2009 ) Characteristics of genes up-regulated and down-regulated after 24 starvation in thehead of Drosophila. , Gene , 446 , 11 - 17
5 . Takahashi, A. ( 2009 ) Effect of exonic splicing regulation on synonymous codon usage
in alternatively spliced exons of Dscam. , BMC Evol. Biol. , 9 , 214 - 0
6 . Watanabe, Y.,Takahashi, A.,Itoh, M. and Takano‐Shimizu, T. ( 2009 ) Molecular
spectrum of spontaneous de novo mutations in male and female germ line cells of
Drosophila melanogaster. , Genetics , 181 , 1035 - 1043
7 . Takahashi, K. H.,Tanaka, K.,Itoh, M., and Takano‐Shimizu, T. ( 2008 ) Reduced Xlinked rare polymorphism in males in comparison to females of Drosophila melanogaster. ,Journal of Heredity , 100 , 97 - 105
POSTER PRESENTATIONS
1 . 高橋 一男, 高野 敏行, Hoffmann A. A. 「 温度ストレス下におけるHsp遺伝子の発生過程
安定化機能 」, 第11回日本進化学会大会 , 札幌 , 9/2-9/4
2 . 高野敏行，高橋亮 「 シスかトランスか？交雑実験による峻別法の批判的再検討 」, 第11回日本進化学会大会 , 札幌 , 9/2-9/4
3 . Takahashi, A.,Takano-Shimizu, T 「 Natural variant of a pigmentation gene and its rolein mating incompatibility 」, The 9th Japanese Drosophila Research Conference ,Kakegawa , 7/6-7/8
4 . Tanaka, K.M.,Takahashi, A.,Itoh, M.,Takano-Shimizu,T. 「 Repair system for fate map
shifts caused by increased bicoid gene dosage. 」, The 9th Japanese Drosophila Research
Conference , Kakegawa , 7/6-7/8
5 . 河邊 昭 「 Arabidopsis 属の動原体周辺領域の組換えの低い領域におけるDNA変異パ
ターン 」, 日本遺伝学会第81回大会 , 松本市 , 9/16-9/18
6 . 塚原小百合、小林啓恵、河邊 昭, 三浦明日香、角谷徹仁 「 シロイヌナズナにおいて転移するレトロトランスポゾンの制御機構 」, 日本遺伝学会第81回大会 , 松本市 , 9/16-9/18
7 . 小林啓恵、河邊 昭、塚原小百合、三浦明日香、角谷徹仁 「 アラビドプシス属における爆発的レトロトランスポジションの再現 」, 日本遺伝学会第81回大会 , 松本市 , 9/16-9/18
8 . 高橋 文、高野敏行 「 キイロショウジョウバエ集団における胸部三叉の色素沈着パターンの多型と非ランダム交配 」, 日本遺伝学会第81回大会 , 松本市 , 9/16-9/18
9 . 田中健太郎、高橋 文、伊藤雅信、高野敏行 「 bicoid 遺伝子コピー数の増加に応答する修復機構の遺伝的多様性 」, 日本遺伝学会第81回大会 , 松本市 , 9/16-9/18
10 . 高野敏行 「 量的形質の理解のために 」, 日本遺伝学会第81回大会 , 松本市 , 9/169/18
11 . Fujikawa, K., Takahashi, A., Takano-Shimizu, T., Nishimura, A., Ishida, Y., Itoh, M.,
Ozaki, M. 「 Genome-wide microarray analysis of increasing the appetite upon starvation in
Drosophila. 」, 50th Annual Drosophila Research Conference , Chicago, Illinois , 3/4-3/8
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No. 60back

E. DEPARTMENT OF INTEGRATED GENETICS
E-a. Division of Human Genetics
E. DEPARTMENT OF INTEGRATED GENETICS
E-a. Division of Human Genetics
Hiroyuki Sasaki
RESEARCH ACTIVITIESPUBLICATIONSPapers
1 . 豊田敦，佐々木裕之 ( 2009 ) 個人に合った医療・予防法の実現に向けて , MMJ , 5 ,196 - 198
2 . Yamaguchi,S.,Kurimoto,K.,Yabuta,Y.,Sasaki,H.,Nakatsuji,N.,Saitou,M.,and Tada,T. (2009 ) Conditional knockdown of Nanog induces apoptotic cell death in mouse migrating
primordial germ cells , Development , 136 , 4011 - 4020
3 . Hirasawa,R., and Sasaki,H. ( 2008 ) Dynamic transition of Dnmt3b expression inmouse pre- and early post-implantation embryos. , Gene Expr. Patt. , 9 , 27 - 30
4 . Takashima,S., Takehashi,M., Lee,J., Chuma,S., Okano,M., Hata,K., Suetake,I.,
Nakatsuji,N., Miyoshi,H., Tajima,S., Tanaka,Y., Toyokuni,S., Sasaki,H., KanatsuShinohara,M., and Shinohara,T. ( 2009 ) Abnormal DNA methyltransferase expression inmouse germline stem cells results in spermatogenesis defects. , Biol. Reprod. , 81 , 155- 164
5 . 一柳健司，佐々木裕之 ( 2009 ) ゲノムワイドなDNAメチル化解析 , 分子細胞治療 , 8 ,372 - 376
6 . 李玉鳳, 佐々木裕之 ( 2009 ) 生命現象と疾患のメカニズムを理解する鍵 -エピジェネティ
クス入門- , Biophilia , 5 , 6 - 10
7 . 佐渡敬，佐々木裕之 ( 2009 ) 哺乳類のエピジェネティクス , 生物の科学：遺伝 , 63 , 65
- 70
8 . Suzuki,J., Yamaguchi,K., Kajikawa,M., Ichiyanagi,K., Adachi,N., Koyama,H., Takeda,S.,
and Okada,N. ( 2009 ) Genetic evidence that the non-homologous end-joining repair
pathway is involved in LINE retrotransposition. , PLoS Genetics , 5 , 1000461 - 0
9 . 宮川（倉持）さとみ，渡部聡朗 ( 2008 ) マウス生殖細胞で発現するsmall RNAの機能 , 実験医学 , 27 , 386 - 392
10 . 佐々木裕之，北條浩彦 ( 2008 ) 機能性小分子RNAの大規模シークエンス , 実験医学, 27 , 14 - 19
11 . Hoki,Y.,Kimura,N.,Kanbayashi,M.,Ohhata,T.,Amakawa,Y.,Sasaki,H., and Sado,T. (2008 ) A proximal conserved repeat in the Xist gene is essential as a genomic element for
X-inactivation in mouse. , Development , 136 , 139 - 146
ORAL PRESENTATION
1 . 佐々木裕之 DNAメチル化による遺伝子発現制御 生体情報機能学講義 九州大学医学部生命科学科 11/16
2 . 佐々木裕之 哺乳類生殖細胞のエピゲノム制御と小分子RNA 第536回生医研・グローバ

ルCOE理医連携セミナー 九州大学生体防御医学研究所 11/11
3 . 一柳健司 エピジェネティクスと進化〜種間・種内におけるエピジェノタイプの多様性 GRL
バイオサイエンスセミナー 静岡大学理学部 10/26
4 . 佐々木裕之 幹細胞の生物学特論「哺乳類生殖細胞のリプログラミング」 奈良先端科学
技術大学院大学講義 奈良先端科学技術大学院大学 10/22
5 . 佐々木裕之 哺乳類生殖細胞のエピゲノムと機能性小分子RNA 奈良先端科学技術大学
院大学セミナー 奈良先端科学技術大学院大学 10/21
6 . 佐々木裕之 哺乳類生殖細胞のエピゲノムと機能性小分子RNA 徳島大学疾患酵素学研究センターセミナー 徳島大学疾患酵素学研究センター 7/8
7 . 佐々木裕之 哺乳類のエピゲノムと機能性小分子RNA 東京工業大学大学院講義 東京
工業大学生命理工学部 6/3
8 . 佐渡敬 X染色体不活性化を担うXist遺伝子のアンチセンス制御機構 BRCセミナー 理
化学研究所バイオリソースセンター 1/29
POSTER PRESENTATIONS
1 . 尼川裕子，保木裕子，佐々木裕之，佐渡敬 「 Prolonged expression of Xist retards X
chromosome reactivation in mouse germ line 」, 第32回日本分子生物学会年会 , 横浜 ,12/9-122 . 一柳健司 「 Acquisition of endonuclease specificity preceded the explosive
amplification of mammalian L1 retrotransposons 」, 第32回日本分子生物学会年会 , 横浜 ,12/9-123 . 新田洋久，一柳健司，宮成悠介，大堀健太，久保田健夫，佐々木裕之 「 Genome wide
DNA methylation analysis of ICF syndrome 」, 第32回日本分子生物学会年会 , 横浜 , 12/912
4 . 李玉鳳，一柳健司，北山淳子，佐々木裕之 「 Locus-specific DNA methylation changes
at mouse SINE B1 elements during male germ cell development 」, 第32回日本分子生物学会年会 , 横浜 , 12/9-12
5 . 福田渓，一柳健司，北山淳子，平井啓久，佐々木裕之 「 Comparison of the genomewide DNA methylation patterns between human and chimpanzee 」, 第32回日本分子生物学会年会 , 横浜 , 12/9-12
6 .
千葉初音，平澤竜太郎，金田正弘，佐々木裕之「 De novo DNA methylation
independent establishment of genomnic imprinting in mouse oocytes 」, 第32回日本分子生物学会年会 , 横浜 , 12/9-12
7 . 鏡味裕，臼井文武，中村隼明，山本耕裕，大友朝子，柏木まや，田上貴寛，韮澤圭二郎，
松原悠子，小野珠乙 「 Genetic regulation of avian stem cells and the application for poultry
breeding 」, 第32回日本分子生物学会年会 , 横浜 , 12/9-12
8 . 山本耕裕，渡部聡朗，保木裕子，佐渡敬，佐々木裕之 「 A novel gene knockdown
method utilizing the PIWI-piRNA silencing pathway in mouse spermatogenesis. 」, 第32回
日本分子生物学会年会 , 横浜 , 12/9-12
9 . 渡部聡朗，中馬新一郎，十時泰，豊田敦，山本耕裕，保木裕子，藤山秋左夫，柴田龍弘，
中辻憲男，佐渡敬，佐々木裕之「 Zucchini is a mitochondrial protein required forspermatogenesis and piRNA biogenesis in mouse. 」, 第32回日本分子生物学会年会 , 横
浜 , 12/9-12
10 . 佐々木裕之 「 The epigenome and functional small RNAs 」, 第32回日本分子生物学会
年会 , 横浜 , 12/9-12
11 . 岩舩浩孝，山口祐希，鈴木智広，古海弘康，橋本昌和，幸田尚，金田秀貴，若菜茂晴，
城石俊彦，佐々木裕之、石野史敏 「 Analysis on mutant mice exhibiting abromal methylationin DMR 」, 第32回日本分子生物学会年会 , 横浜 , 12/9-12
12 . 保木裕子，大畑樹也，佐々木裕之，佐渡敬 「 A partial loss of function mutation in themechanism of X chromosome inactivation 」, 第32回日本分子生物学会年会 , 横浜 , 12/912
13 . Sasaki,H. 「 Epigenetics and small RNAs in mammalian germ cells 」, TriRhena
Chromatin/Transcription Club Meeting , Friburg,Germany , 5/12
14 . Sasaki,H. 「 The Epigenome and Small RNA Repertoire in Mammalian Germ Cells 」,
EMBO Conference Series on Chromatin and Epigenetics , Heidelberg,Germany , 5/13-17
15 . Sasaki,H. 「 Genomic imprinting,DNA methylation and small RNAs in mammaliangerm cells 」, Gordon Research Conferences "Epigenetics" The Role of the Environment
and Epigenetic Mechanisms in Behavior,Health,and Disease , Holderness,NH,USA , 8/914
16 . Sasaki,H. 「 Imprinting,DNA methylation and small RNA in germ cells. 」, Mouse
Genetics ＆ Genomics:Development ＆ Disease , Hinxton,UK , 9/2-6
17 . 新田洋久，一柳健司，宮成悠介，大堀健太，久保田健夫，佐々木裕之 「 ICF症候群のゲ
ノムワイドDNAメチル化解析 」, 日本人類遺伝学会第54回大会 , 東京 , 9/23-26
18 . Miyanari,Y. 「 Profiling of DNA methylation during spermatogenesis 」, Keystone
Symposium , Keystone,USA , 1/5-9
19 . 佐々木裕之 「 マウス生殖系列におけるインプリンティング、DNAメチル化と小分子RNA」, 文部科学省・科学研究費補助金・特定領域研究「生殖系列の世代サイクルとエピゲノムネッ
トワーク」第2回公開シンポジウム , 東京 , 11/26-27
20 . 佐々木裕之 「 哺乳類生殖細胞のエピジェネティクスと小分子RNA 」, 第7回RCGMフロン
ティアシンポジウム『未来医療のためのゲノム医学研究』 , 埼玉 , 11/3
21 . 山口裕子，鳥巣弘道，中林一彦，田辺香子，田山千春，菅原直子，佐々木裕之，森崇英，北折珠央，杉浦真弓，秦健一郎 「 異常妊娠のエピゲノム解析 」, 日本人類遺伝学会第54回大会 , 東京 , 9/23-26
22 . 一柳健司，福田渓，北山淳子，平井啓久，佐々木裕之 「 ヒトとチンパンジーのDNAメチ
ル化プロファイルの比較 」, 日本人類遺伝学会第54回大会 , 東京 , 9/23-26
23 . 佐々木裕之 「 ゲノムインプリンティングのエピゲノム機構に関する研究 」, 日本人類遺伝学会第54回大会 , 東京 , 9/23-26
24 . 佐々木裕之 「 次世代シークエンサーによる機能性小分子RNAの網羅的解析 」, 日本遺伝学会第81回大会 , 長野 , 9/16-18
25 . 一柳健司，北山淳子，李王鳳，佐々木裕之 「 生殖細胞形成過程におけるマウスB1
SINEのDNAメチル化ダイナミクス 」, 日本遺伝学会第81回大会 , 長野 , 9/16-18
26 . 一柳健司，中島亮，梶川正樹，岡田典弘 「 TANT法によるLINE転移機構の解析：バイオ
インフォマティクスから見えてきたLINE転移における宿主タンパク質の関与 」, 日本遺伝学会
第81回大会 , 長野 , 9/16-18
27 . 尼川裕子，保木裕子，佐々木裕之，佐渡敬 「 マウスのメス生殖細胞におけるXist発現消失時期の遅延はX染色体再活性化を遅らせる 」, 日本遺伝学会第81回大会 , 長野 , 9/16-18
28 . 保木裕子，大畑樹也，佐々木裕之，佐渡敬 「 X染色体不活性化機構の部分的機能欠損
変異 」, 日本遺伝学会第81回大会 , 長野 , 9/16-18
29 . 渡部聡朗 「 Zucchini遺伝子KOマウスを用いた、piRNAとDNAメチル化の解析 」, 特定領域研究『生殖系列の世代サイクルとエピゲノムネットワーク』生殖サイクル若手勉強会2009 ,静岡 , 8/27-29
30 . Sasaki,H. 「 The epigenome and small RNA repertoire in mammalian germ cells 」,
The 24th Naito Conference on Nuclear Dynamics and RNA[II] , 札幌 , 6/23-26
31 . Amakawa,Y.,Hoki,Y.,Sasaki,H.,Sado,T. 「 The impact of Xist RNA on X chromosome
reactivation in PGCs 」, The 24th Naito Conference on Nuclear Dynamics and RNA[II] , 札
幌 , 6/23-26
32 . Ichiyanagi,K.,Kitayama,J.,Sasaki,H. 「 Locus-specific hyper- and hypo-methylation ofmouse B1 SINE in male germ cells 」, The 24th Naito Conference on Nuclear Dynamics
and RNA[II] , 札幌 , 6/23-26
33 . Sado,T. 「 Toward the understanding of molecular events underlying X-inactivation 」,
The 24th Naito Conference on Nuclear Dynamics and RNA[II] , 札幌 , 6/23-26
34 . 佐々木裕之 「 私の研究人生 」, 特定領域研究『生殖系列の世代サイクルとエピゲノムネ
ットワーク』生殖サイクル若手勉強会2009 , 静岡 , 8/27-29
35 . 渡部聡朗，三ツ矢幸造，宮川さとみ，中馬新一郎，富澤信一，十時泰，豊田敦，山本耕裕，保木裕子，佐渡敬，野瀬俊明，仲野徹，佐々木裕之 「 piRNAによるインプリント遺伝子
Rasgrf1のDNAメチル化制御 」, 第11回RNAミーティング（第11回日本RNA学会年会） , 新潟
, 7/27-29
36 . 佐々木裕之 「 生殖細胞のエピゲノムと機能性RNA 」, 第33回阿蘇シンポジウム”生命科
学のフロントランナー” , 熊本 , 7/31,8/1
37 . 佐々木裕之 「 発生・成長におけるエピジェネティクス 」, 第13回小児分子内分泌研究会, 北海道 , 7/4-5
38 . 佐々木裕之 「 哺乳類生殖細胞のエピゲノムと機能性小分子RNA 」, 文部科学省科学研
究費補助金特定領域研究「遺伝情報発現におけるDECODEシステムの解明」 , 新潟 , 1/19-

21
39 . 佐々木裕之 「 エピジェネティクスが拓く生命科学 」, 2009 Millipore Asia BioForum 幹細胞およびエピジェネティクス研究の最前線 , 東京 , 6/15
40 . 尼川裕子，保木裕子，佐々木裕之，佐渡敬 「 恒常活性型XistアリルがX染色体再活性化に与える影響 」, 第3回日本エピジェネティクス研究会年会 , 東京 , 5/22-23
41 . 一柳健司，北山淳子，佐々木裕之 「 マウス生殖細胞および体細胞におけるB1 SINEのDNAメチル化プロファイル 」, 第3回日本エピジェネティクス研究会年会 , 東京 , 5/22-23
42 . 千葉初音，平澤竜太郎，金田正弘，佐渡敬，佐々木裕之 「 X 染色体のインプリンティン
グには新規 DNA メチル化は不要である 」, 第3回日本エピジェネティクス研究会年会 , 東京 ,5/22-2343 . Ichiyanagi,K.,Kitayama,J.,and Sasaki,H. 「 Locus-specific hyper- and hypo-methylationof mouse B1 elements in male germ cells. 」, 2nd International Conference and Workshop"Genomic Impact of Eukaryotic Transposable Elements" , Pacific Grove, USA , 2/6-10
EDUCATION
1 . Sasaki,H. From Imprinting to the Epigenome in 25 years CellCentric Conference
2009 UK 9/4-6
2 . Sasaki,H. Nuclear Dynamics and RNA[Ⅱ] The 24th Naito Conference 札幌 6/23-26
3 . 佐々木裕之 千里ライフサイエンスセミナー エピジェネティクス：ゲノムを管理し活用する
戦略 大阪 4/17
BOOK
1 . Kaneda,M., and Sasaki,H. ( 2009 ) Genomic imprinting and X chromosome
inactivation in germ cell development Genetic and Epigenetic Control of MammalianGerm Cell Development and Function 37 - 56
2 . 佐々木裕之 ( 2009 ) ４章．ゲノムの高度活用戦略ーエピジェネティクス 現代生物科学入門１ゲノム科学の基礎 153 - 200
OTHERS1 . 佐々木裕之 , 2 , 日本人類遺伝学会賞「ゲノムインプリンティングのエピゲノム機構に関す
る研究」
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E. DEPARTMENT OF INTEGRATED GENETICS
E-b. Division of Agricultural Genetics
E. DEPARTMENT OF INTEGRATED GENETICS
E-b. Division of Agricultural Genetics
Keiichi Shibahara
RESEARCH ACTIVITIESPUBLICATIONSPapers
1 . Ono, T., Nishijima, H., Adachi, N., Iiizumi, S., Koyama, H., Shibahara, K-i. ( 2009 )Generation of tetracycline-inducible conditional gene knockout cells in a human Nalm-6 cellline. , J. of Biotechonology , 141 , 1 - 7
2 . Nishijima, H., Adachi, N., Takami, Y., Nakayama, T., and Shibahara, K-i. ( 2009 )Improved applications of the tetracycline-regulated gene depletion. , BioScience Trends ,3 , 161 - 167
3 . Takata, H., Nishijima, H., Ogura, S-i., Sakaguchi, T., Bubulya, P.A.,Mochiduki, T.,
andShibahara, K-i.. ( 2009 ) Proteome Analysis of Human Nuclear Insoluble Fractions. ,Genes Cells , 14 , 975 - 990
POSTER PRESENTATIONS
1 . Sharma,A.,Takata,H.,Shibahara,K., Bubulya,A.,Bubulya,P. 「 Son is Essential for
Nuclear Speckle Organization and Cell Cycle Progression. 」, ASCB 49th annual meeting ,San Diego , 12/5-12/9
2 . 高田英昭,西嶋仁,小倉俊一郎,望月徹,柴原慶一 「 核不溶性画分のプロテオーム解析 」,
BMB2008 , 神戸 , 12/11
3 . 宇和田淳介,田中新菜,山口祐太郎,柴原慶一,中尾光善,斉藤寿仁 「 Identification andCharacterization of SUMO-Interacting Motif in the p150 Subunit of Chromatin Assembly
Factor 1 in the Context of DNA Replication 」, 日本エピジェネティックス研究会 , , 5/22-5/23
4 . 宇和田淳介,田中新菜,山口祐太郎,柴原慶一,中尾光善,斉藤寿仁 「 Identification andCharacterization of SUMO-Interacting Motif in the p150 Subunit of Chromatin Assembly
Factor 1 in the Context of DNA Replication 」, 日本分子生物学会春季シンポジウム , 宮崎 ,5/11-5/12
5 . 柴原慶一 「 ヒト疾患原因遺伝子のジーンターゲティング細胞株の作製とその応用 」, 都市
エリア事業外部評価会議 , 静岡 , 1/20
PATENT1 . 2009-110353 , 組換えタンパク質の大量生産に利用可能な細胞株の作製と応用 , 柴原慶
一、西嶋仁、坂口武久 , 大学共同利用機関法人情報・システム研究機構
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E. DEPARTMENT OF INTEGRATED GENETICS
E-b. Division of Agricultural Genetics
E. DEPARTMENT OF INTEGRATED GENETICS
E-b. Division of Agricultural Genetics
Tetsuji Kakutani
RESEARCH ACTIVITIESPUBLICATIONSPapers
1 . Miura A, Nakamura M, Inagaki S, Kobayashi A, Saze H, Kakutani T ( 2009 ) An
Arabidopsis jmjC-domain protein protects transcribed genes from DNA methylation at CHG
sites , EMBO Journal. , 28 , 1078 - 1086
2 . Schoft V, Chumak N, Mosiolek M, Slusarz L, Komnenovic V, Brownfield L, Twell D,
Kakutani T, Tamaru H ( 2009 ) Induction of RNA-directed DNA methylation upon
decondensation of constitutive heterochromatin , EMBO Reports , 10 , 15 - 21
3 . Tsukahara S, Kobayashi A, Kawabe A, Mathieu O, Miura A, Kakutani T ( 2009 ) Burstsof retrotransposition reproduced in Arabidopsis , Nature , 461 , 423 - 426
ORAL PRESENTATION
1 . 角谷徹仁 集中講義
2 . 角谷徹仁 集中講義

福井大学 9/9-9/10
東京大学理学部 10/1-10/2

POSTER PRESENTATIONS
1 . Kakutani T 「 Genetics of DNA methylation in genes and transposons in Arabidopsis
thaliana 」, EMBL conference on Chromatin and Epigenetics , Heidelberg, Germany ,5/13-5/17
2 . Kakutani T 「 Genetics of DNA methylation in Arabidopsis 」, 発生生物学会シンポジウ
ム , 新潟 , 5/29-5/31
3 . Kakutani T 「 Genetics of DNA methylation in Arabidopsis thaliana 」, The 24th Naito
Conference on Nuclear Dynamics and RNA , 札幌 , 6/23-6/26
4 . Kakutani T 「 Genetics of DNA Methylation in Genes and Transposons in Arabidopsis」, Gordon Research Conference on Epigenetics , Holderness, NH, USA , 8/9-8/14
5 . 塚原小百合、小林啓恵、河辺昭、三浦明日香、角谷徹仁 「 シロイヌナズナにおいて転移す
るレトロトランスポゾンの制御機構 」, 日本遺伝学会第８１回大会 , 松本 , 9/16-9/18
6 . 小林啓恵、塚原小百合、河辺昭、三浦明日香、角谷徹仁 「 アラビドプシス属における爆発的レトロトランスポジションの再現 」, 日本遺伝学会第８１回大会 , 松本 , 9/16-9/18
7 . 付ゆう、小林啓恵、、角谷徹仁 「 シロイヌナズナの転移するトランスポゾンVANDAL21のエピジェネティックな制御 」, 日本遺伝学会第８１回大会 , 松本 , 9/16-9/18
8 . 佐々木卓、小林啓恵、佐瀬英俊、角谷徹仁 「 シロイヌナズナのddm1変異体自殖系統におけるDNAメチル化制御の解析 」, 日本遺伝学会第８１回大会 , 松本 , 9/16-9/18
9 . 稲垣宗一、三浦明日香、中村みゆき、小林啓恵、佐瀬英俊、角谷徹仁 「 シロイヌナズナの
jumonjiドメイン蛋白質が転写されている遺伝子のDNAメチル化を防ぐ 」, 日本遺伝学会第８１回大会 , 松本 , 9/16-9/18
10 . Kakutani T, Saze H, Miura A, Inagaki S, Kobayashi A, Nakamura M, Tsukahara S, Fu
Y 「 Genetics of DNA methylation in genes and transposons in Arabidopsis 」, 第３２回分子生物学会年会シンポジウムEmerging power of epigenomics in life science , 横浜 , 12/10
OTHERS1 . 稲垣宗一、三浦明日香、中村みゆき、小林啓恵、佐瀬英俊、角谷徹仁 , 2 , 第８２回遺伝学会Best Paper賞
2 . 角谷徹仁 , 1 , 日本エピジェネティクス研究会幹事
3 . 角谷徹仁 , 3 , Associate Editor, PLoS Genetics
4 . 角谷徹仁 , 3 , Editorial Board member, Epigenetics & ChromatinbackAnnual Report 2009

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E. DEPARTMENT OF INTEGRATED GENETICS
E-c. Division of Brain Function
E. DEPARTMENT OF INTEGRATED GENETICS
E-c. Division of Brain Function
Tatsumi Hirata
RESEARCH ACTIVITIESPUBLICATIONSPapers
1 . Nakadate, Y., Uchida, K., Shikata, K., Yoshimura, S., Azuma, M., Hirata, T., Konishi, H.,
Kiyama, H., and Tachibana, T. ( 2008 ) The formation of argpyrimidine, a methylglyoxal–
arginine adduct, in the nucleus of neural cells. , Biochem. Biophys. Res. Comm. , 378 ,
209 - 212
POSTER PRESENTATIONS
1 . 川崎能彦,平田たつみ 「 嗅球軸索投射におけるNrp2のSema3Aシグナル阻害作用 」, 第42回日本発生生物学会年会 , 新潟 , 5/29-31
2 . Suzuki, I.,Gojobori, T.,Hirata, T 「 Emergence of the layer structure in the mammalian
neocortex associated with a change in the stem cells dynamics 」, Symposium on Evolution, Cold Spring Harbor, USA , 5/27
3 . Suzuki, I.,Gojobori, T.,Hirata, T 「 Evolutionary Origin of Mammalian Specific Features of
the Neocortex 」, Albany 2009: Conversation 16 , Albany, NY, USA , 9/17
4 . 鈴木郁夫,五條堀孝,平田たつみ 「 哺乳類大脳皮質層構造の進化的起原と神経幹細胞ダ
イナミクスの変更 」, 第32回日本神経科学会年会 , 名古屋 , 9/17
5 . Kawasaki, T.,Hirata, T 「 Novel function of Nrp2 as an inhibitor of Sema3A signaling in
the projection of olfactory bulb axons 」, Construction and reconstruction of the brain , Awaji, 10/8-10
6 . Suzuki, I.,Gojobori, T.,Hirata, T 「 Evolutionary emergence of layer structure in the
mammalian neocortex associated with a change in neural stem cell dynamics 」,
Construction and Reconstruction of the Brain , Awaji , 10/7
7 . 川崎能彦 「 嗅球軸索投射におけるセマフォリンシグナルの機能 」, 日本発生生物学会
秋季シンポジウム , 三島 , 11/27-29
OTHERS1 . 平田たつみ , 1 , JST さきがけ領域アドバイザー
2 . 平田たつみ , 1 , 科学技術振興機構 男女共同参画アドバイザリーコミッティー
3 . 平田たつみ , 1 , 日本神経科学学会男女共同参画推進委員長
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F. GENETIC STRAINS RESEARCH CENTER
F-a. Mammalian Genetics Laboratory
F. GENETIC STRAINS RESEARCH CENTER
F-a. Mammalian Genetics Laboratory
Toshihiko Shiroishi
RESEARCH ACTIVITIESPUBLICATIONSPapers
1 . Suzuki D., Yamada A., Amano T., Yasuhara R., Kimura, A., Sakahara, M., Tsumaki, N.,
Takeda, S., Tamura, M., Nakamura, M., Wada, N., Nohno, T., Shiroishi, T., Aiba, A. andKamijo, R. ( 2009 ) Essential mesenchymal role of small GTPase Rac1 in interdigitalprogrammed cell death during limb development. , Dev. Biol. , 335 , 396 - 406
2 . The disruption of Sox21-mediated hair shaft cuticle differentiation causes cyclic
alopecia in mice. ( 2009 ) Kiso, M., Tanaka, S., Saba, R., Matsuda, S., Shimizu, A.,
Ohyama, M., Okano, H.J., Shiroishi, T., Okano, H. and Saga, Y. , Proc. Natl. Acad. Sci.
USA , 106 , 9292 - 9297
3 . Moriwaki, K., Miyashita, N., Mita, A., Gotoh, H., Tsuchiya, K., Kato, H., Mekada, K.,
Noro, C., Oota, S., Yoshiki, A., Obata, Y., Yonekawa, H. and Shiroishi, T. ( 2009 ) Uniqueinbred strain MSM/Ms established from the Japanese wild mouse. , Exp. Anim. , 58 , 123- 134
4 . Fujisawa, H., Horiuchi, Y., Harushima, Y., Takada, T., Eguchi, S., Mochizuki, T.,
Sakaguchi, T., Shiroishi, T. and Kurata, N. ( 2009 ) SNEP: Simultaneous detection of
nucleotide and expression polymorphisms using Affymetrix GeneChip. ,BMC
Bioinformatics. , 10 , 131 - 0
5 . Sagai, T., Amano, T., Tamura, M., Mizushina, Y., Sumiyama, K., and Shiroishi, T. ( 2008
) A cluster of three long-range enhancers directs regional Shh expression in the epithelial
linings , Development , in press , 0 - 0
POSTER PRESENTATIONS
1 . Amano, T., Sagai, T., Tanabe, H. and Shiroishi, T. 「 Long-range enhancer-promoter
interaction via chromosomal dynamics at the Shh locus 」, 23th INTERNATIONAL MOUSE
GENOME CONFERENCE 2009 , La Jolla, San Diego, USA , 11/1-11/4
2 . Tamura, M., Hosoya, M., Amano, T., Tanaka, S., Kato, Y., Sagai, T. and Shiroishi, T. 「A mouse mutation Rim4 with duplication of a 7Mb segment of chromosome 8 is model ofPartial trisomy 4q-ter syndrome that exhibits congenital malformation 」,
23th
INTERNATIONAL MOUSE GENOME CONFERENCE 2009 , La Jolla, San Diego, USA ,11/1-11/4
3 . Takada, T., Mita, A., Ebata, T., Shin-i, T., Toyoda, A., Fujiyama, A., Kohara, Y., Obata,Y., Moriwaki, K., Yonekawa, H. and Shiroishi, T. 「 Genetic dissection of age-associatedphenotypes using intersubspecific consomic strains. 」, 23th INTERNATIONAL MOUSE
GENOME CONFERENCE 2009 , La Jolla, San Diego, USA , 11/1-11/4
4 . Takada, T. 「 Making a database to link mouse genome diversity and phenotype 」,

International Phenome Integration Meeting RIKEN/InterPhenome/CASIMIR , Shiga, Japan ,7/12-7/13
5 . 天野孝紀, 城石俊彦 「 染色体ダイナミクスを介したShh遺伝子の動的発現制御 」, 日本遺伝学会第81回大会ワークショップ「核ダイナミクス研究の新展開」2009 , 松本 , 9/16-9/18
6 . 天野孝紀 「 Long-rangeエンハンサーとShh遺伝子領域の染色体ダイナミクス 」, 東京大学
先端科学技術研究センターセミナー , 東京 , 5/8
7 . Oka, A. and Shiroishi, T. 「 Meiotic cell-cycle arrest serves as reproductive barrier inmouse speciation 」, 42nd Annual Meeting for the Japanese Society of Developmental
Biologists, Symposium-2 , Niigata , 5/28-5/31
8 . 田村勝, 小見山博光, 加藤依子, 城石俊彦 「 GASDERMIN B (GSDMB) の組織および癌
特異的発現は、5’上流に挿入されたレトロトランスポゾンにより制御される 」, 日本遺伝学会第81回大会 , 松本 , 9/16-9/18
9 . 田村勝 「 bHLH型転写因子Hand2のGene dose effectによるマウス形態異常とヒト先天性異常 」, 第23回モロシヌス研究会 , 滋賀 , 7/11-7/12
10 . 田中成和, 田村勝, 加藤依子, 城石俊彦 「 Mutation of Gsdma3 induces spontaneous
squamous cell carcinoma development 」, 日本分子生物学会第32回大会 , 横浜 , 12/912/12
11 . 高田豊行 「 日本産野生マウス由来系統の遺伝的多様性を基盤とした機能ゲノム学 」,
かずさDNA研究所ワークショップ 「遺伝的多様性に基づく有用遺伝子座の探索」 , 千葉 ,3/25
12 . 高田豊行, 三田晃彦, 森脇和郎, 米川博通, 城石俊彦 「 マウス亜種間コンソミック系統を用いたエネルギー代謝多様性の遺伝解析 」, 日本遺伝学会第81回大会 , 松本 , 9/16-9/18
13 . 高田豊行, 三田晃彦, 森脇和郎, 米川博通, 城石俊彦 「 マウス亜種間コンソミック系統群を用いた多因子肥満症の遺伝解析 」, 第56回日本実験動物学会総会 , 大宮 , 9/14-9/16
14 . 高田豊行, 江端俊伸, 小原雄治, 城石俊彦 「 NIG Mouse Functional Genomics
Database 」, 文科省統合データベースプロジェクト「データベースが拓くこれからのライフサイエ
ンス」 , 東京 , 6/12
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F. GENETIC STRAINS RESEARCH CENTER
F-b. Mammalian Development Laboratory
F. GENETIC STRAINS RESEARCH CENTER
F-b. Mammalian Development Laboratory
Yumiko SagaRESEARCH ACTIVITIESPUBLICATIONSPapers
1 . Kawashima H., Hirakawa J., Tobisawa Y., Fukuda M.,and Saga Y ( 2009 ) Conditional
gene targeting in mouse high endothelial venules. , J Immunol , 182 , 5461 - 5468
2 . Kiso M., Tanaka S., Saba R., Matsuda S., Shimizu A., Ohyama M., Okano HJ., ShiroishiT., Okano H.,and Saga Y. ( 2009 ) he disruption of Sox21-mediated hair shaft cuticle
differentiation causes cyclic alopecia in mice. , Circ Res. , 106 , 9292 - 9297
3 . Ukita K., Hirahara S., Oshima N., Imuta Y., Yoshimoto A., Jang CW., Oginuma M., Saga
Y., Behringer RR., Kondoh H., and Sasaki H. ( 2009 ) Wnt signaling maintains thenotochord fate for progenitor cells and supports the posterior extension of the notochord. ,Mech Dev , 126 , 791 - 803
4 . Sada A., Suzuki A., Suzuki H., Saga Y. ( 2009 ) The RNA-binding protein NANOS2 isrequired to maintain murine spermatogonial stem cells. , Science , 325 , 1394 - 1398
5 . Suzuki H., Sada A., Yoshida S.,and Saga Y. ( 2009 ) The heterogeneity ofspermatogonia is revealed by their topology and expression of marker proteins including
the germ cell-specific proteins Nanos2 and Nanos3. , Dev. Biol. , 336 , 222 - 231
6 . Yamaji M., Tanaka T., Shigeta M., Chuma S., Saga Y.,and Saitou M. ( 2009 )Functional reconstruction of Nanos3 expression in the germ cell lineage by a noveltransgenic reporter reveals distinct subcellular localizations of Nanos3. , Reproduction. ,, 0-0
POSTER PRESENTATIONS
1 . Nobuo Sasaki.,Makoto Kiso.,and Yumiko Saga. 「 Repression of the Notch signaling
activity via Mesp2 is essential for somitogenesis 」, 16th International Society ofDevelopmental Biologists Congress 2009 , Edinburgh , 9/6-10
2 . 相賀 裕美子.,荻沼政之 「 A translation mechanism of the segmentation clock forperiodic somite formation 」, 第３２回 日本分子生物学会 , 横浜市 , 12/9～12
3 . Stanley-Troy Artap,Kylie Lopes Floro,Yumiko Saga 「 Ｃｉｔｅｄ２ ｔｒａｎｓａｃｔｉｂａｔｅｓ Ｎｏｄａｌ
ｅｘｐｒｅｓｓｉｏｎ ｉｎ ｔｈｅ ｌｅｆｔ ｌａｔｅｒａｌ ｐｌａｔｅ ｍｅｓｏｄｅｒｍ ｔｈｒｏｕｇｈ ｉｎｔｅｒａction with FoxH1」, 16th International Society of Developmental Biologists Congress 2009 , Edinburgh ,9/6-104 . Aiko Sada.,Atsushi Suzuki.,Hitomi Suzuki.,and Yumiko Saga. 「 Nanos2 is an intrinsic
regulator for maintaining an undifferentiated state of spermatogonial stem cells 」, 16th
International Society of Developmental Biologists Congress 2009 , Edinburgh , 9/6-10
5 . Rie Saba.,Atsushi Suzuki.,Hitomi Suzuki.,Aiko Sada.,and Yumiko Saga. 「 Nanos2
regulates the transcriptome in the embryonic male germ cells 」, 16th International Society

of Developmental Biologists Congress 2009 , Edinburgh , 9/6-10
6 . Yumiko Saga 「 マウスの生殖細胞の性分化制御機構 」, 第82回日本生化学会大会シンポジウム , 神戸ポートピアホテル , 10/21
7 . 淺井理恵子.,栗原由紀子.,佐藤崇裕.,河村悠美子.,小久保博樹.,相賀 裕美子.,宮川-富田幸子.,栗原裕基 「 Endothelin type-A receptor expression defines a distinct subdomain within
the first heart field contributing to chamber myocardium 」, 第３２回 日本分子生物学会 , 横浜市 , 12/9-12
8 . 小山敏尚.,張ｹ谷健一.,佐々木伸雄.,岡村佳明.,相賀裕美子.,穂積勝人.,菅波晃子.,田村裕.,
坂本玲子.,佐藤充治.,吉田進昭.,and 北川元生. 「 Mastermind-1/Mastermind-2 are essential
components of Notch signaling pathway 」, 第３２回 日本分子生物学会 , 横浜市 , 12/9-12
9 . 小山敏尚,張ｹ谷健一,佐々木伸雄,岡村佳明,相賀裕美子,穂積勝人,菅波晃子,田村裕,坂本玲子,佐藤充治,吉田進昭,北川元生.
「 Mastermind-1/Mastermind-2 are essential
components of Notch singnaling pathway 」, 第３２回 日本分子生物学会 , 横浜市 , 12/912
10 . 松尾萌、相賀裕美子、武田洋幸、越田澄人 「 Functional analyses of Ktu, a cytoplasmic
protein required in motile ciliogenesis 運動性繊毛形成に関わるマウスKtuタンパクの機能解析 」, 第３２回 日本分子生物学会 , 横浜市 , 12/9-12
11 .
高橋雄、安彦行人、相賀裕美子、菅野純「 Segmentation and rostro-caudal
patterning of somites is not essential for vertebral body segmentation 」, 第３２回 日本分子生物学会 , 横浜市 , 12/9-12
12 . 高橋潤、大林享子、荻沼正之、相賀裕美子、高田慎治 「 Ripply genes are required forthe proper rostro-caudal patterning through degradation of Tbx6 protein duringsomitogenesis 」, 第３２回 日本分子生物学会 , 横浜市 , 12/9-12
13 . 佐々木伸雄、相賀裕美子 「 Functional analays of the degradation mechanism ofMastermind via Mesp2 to repress the activation of the Notch signaling pathway 」, 第３２回
日本分子生物学会 , 横浜市 , 12/9-12
14 . 山路剛史、田中敬、繁田痲葉、中馬新一郎、相賀裕美子、斎藤通紀「 Functional
reconstruction of Nanos3 expression in the germ cell lineage by a novel transgenic reporter
identifies distinct subcellular localizations of Nanos3 」, 第３２回 日本分子生物学会 , 横浜
市 , 12/9-12
15 . 小久保博樹、相賀裕美子 「 Hesr functions in vascular remodeling process 」, 第３２回
日本分子生物学会 , 横浜市 , 12/9-12
16 . 坂部正英、小久保博樹、中島祐司、相賀裕美子 「 Ectopic retinoic acid signaling
induces transposition of great arteries(TGA)via suppressing Tbx2 expression during outflow
cushion formation 」, 第３２回 日本分子生物学会 , 横浜市 , 12/9-12
17 . 佐波理恵、鈴木敦、鈴木仁美、佐田亜衣子、相賀裕美子 「 Nanos2 regulates thetranscriptome in the embryonic male germ cells Nanos2によるマウス胎仔期の雄性生殖細胞
ﾄﾗﾝｽｸﾘﾌﾟﾄｰﾑ制御機構 」, 第３２回 日本分子生物学会 , 横浜市 , 12/9-12
18 . Aiko Sada,Atsushi Suzuki,Hitomi Suzuki,Yumiko Saga 「 Nanos2 maintains
undifferentiated state of spermatogonial stem cells 」, 第42回 発生生物学会 , 新潟市 ,5/29-5/31
19 . Jun Takahashi,Akiko Ohbayashi,Yumiko Saga,Shinji Takada 「 The function of
Ripply and Ripply２ in the somite formation 」, 第42回 発生生物学会 , 新潟市 ,5/28-5/31
20 . Yusuke Okubo,Yumiko Saga 「 The coupling mechanism to generate synchronizedoscillation in mouse somitogenesis 」, 第42回 発生生物学会 , 新潟市 , 5/
21 . Atsushi Suzuki, Rie Saba, Yumiko Saga 「 Nanos2 promotes sexual differentiation ofmale germ cells 」, Keystone symposium , Santa Fe , 2/1-6
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F. GENETIC STRAINS RESEARCH CENTER
F-c. Mouse Genomics Resource Laboratory
F. GENETIC STRAINS RESEARCH CENTER
F-c. Mouse Genomics Resource Laboratory
Tsuyoshi Koide
RESEARCH ACTIVITIESPUBLICATIONSPapers
1 . Umemori, J.,Nishi, A.,Lionikas, A.,Sakaguchi, T.,Kuriki, S.,Blizard, D.A.,Koide, T. (2009 ) QTL analyses of temporal and intensity components of home-cage activity in KJR
and C57BL/6J strains , BMC Genetics , 10 , 40 - 0
2 . Koide, T., Catanesi, C.I., Nishi, A., Shiroishi, T., Kasai, S., Ikeda, K., Takahashi, A. (2009 ) Systematic mapping of pain-related QTL using consomic mouse strains: Advantage
of using wild-derived strains , Brain Research Journal , 2 , 0 - 0
ORAL PRESENTATION
1 . 小出剛 マウス行動多様性の遺伝的基盤を探る 北海道大学獣医学研究談話会 北海道
大学獣医学部 3/23
POSTER PRESENTATIONS
1 . 小出剛 「 マウスにおけるコミュニケーションとその遺伝的要因－行動遺伝学を通して 」, 平
成21年11月5日 金沢大学創基150年記念「講演会・シンポジウム」「社会認識」学際脳科学シンポジウム , 金沢 , 11/5
2 . 小出剛，下位香代子，榊原啓之 「 動物行動多様性に関わる環境－遺伝子相互作用 」,
脳を巡る環境－遺伝子相互作用の分子基盤 , 東京 , 8/29
3 . Sugimoto, H., Takahashi, A., Shiroishi, T., Koide, T. 「 Molecular and genetic analysis
for aggressive behavior using B6-MSM consomic mouse strains 」, 11th Annual Meeting of
the International Behavioural and Neurogenetics Society , Dresden , 6/4-8
4 . Umemori, J., Uno, T., Yuasa, S., Koide, T. 「 Decreased expression of myelination
associated genes in genetic incompatibility mice, Genic mice 」, 23rd International
Mammalian Genome Conference , La Jolla Torrey Pines, California , 11/1-4
5 . 梅森十三，近藤亮太，宇野毅明，湯浅茂樹，小出剛 「 遺伝的不適合による神経発達異常」, 第56回日本実験動物学会 , 大宮 , 5/14-16
6 . 石井亜矢子，西明紀，城石俊彦，小出剛 「 B6-MSMコンソミックマウス系統を用いた自発活動性の遺伝学的解析 」, 第32回日本神経科学大会 , 名古屋 , 9/16-18
7 . 梅森十三，宇野毅明，湯浅茂樹，小出剛 「 遺伝的不適合マウスは脊髄オリゴデンドロサイ
トの成熟が異常である 」, 第32回日本神経科学大会 , 名古屋 , 9/16-18
8 . 杉本大樹，高橋阿貴，城石俊彦，小出剛 「 マウス攻撃行動における遺伝的基盤の解析」, 第32回日本神経科学大会 , 名古屋 , 9/16-18
9 . 田邉彰，石井亜矢子，城石俊彦，高橋阿貴，小出剛 「 コンソミックマウス系統を用いた不安様行動の高解像度マッピング 」, 第32回日本神経科学大会 , 名古屋 , 9/16-18

EDUCATION
1 . 森裕司，小出剛 第5回行動遺伝学研究会 国立遺伝学研究所研究会 三島 3/12
2 . Koide, T., Palmer, A. Molecular and genetic approaches towards understanding
behavior 第32回日本分子生物学会シンポジウム 横浜 12/10
BOOK
1 . Koide, T., Catanesi, C.I., Nishi, A., Shiroishi, T., Kasai, S., Ikeda, K., Takahashi, A. (2009 ) Advantage of using wild-derived mouse strains for a variety of pain-related studies:
Genetic diversity and new genetic tools Acute pain: Causes, effects and treatment 0 0
2 . 小出剛 ( 2009 ) マウスを使って実験を始めよう マウス実験の基礎知識 9 - 22backAnnual Report 2009

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F. GENETIC STRAINS RESEARCH CENTER
F-d. Model Fish Genomics Resource
F. GENETIC STRAINS RESEARCH CENTER
F-d. Model Fish Genomics Resource
Noriyoshi Sakai
RESEARCH ACTIVITIESPUBLICATIONSPapers
1 . Kawasaki, T., Saito, K., Mitsui, K., Ikawa, M., Yamashita, M., Tanaiguchi, Y., Takeda, S.,
Mitani, K., Sakai, N. ( 2009 ) Introduction of a foreign gene into zebrafish and medaka cells
using adenoviral vectors , Zebrafish , 6 , 253 - 258
ORAL PRESENTATION
1 . Sakai, N. メダカからアマゴ、ニジマス、そしてゼブラフィッシュ －魚類の発生を追いかけて－ 東北大学農学部キャリア形成支援セミナー 東北大学・農学部 11/11
POSTER PRESENTATIONS
1 . Sakai, N. 「 Recent progress of male germ cell culture and virus vectors 」, The
Zebrafish Knockout Project: Organization and Strategy Meeting , Cambridge, UK , 3/7-3/9
2 . Saito, K.,Sakai, N. 「 Distributed pattern of the pre-replicative complex component Sld5
on the division of long cell cycle spermatogonial stem cells in zebrafish 」, 第41回発生生物学会 , 新潟 , 5/28-5/31
3 . Kawasaki, T.,Shinya, M.,Sakai, N. 「 Self-renewal and differentiation of spermatogonial
stem cells maintained by grafting the dissociated testicular cells in zebrafis 」, 第41回発生生物学会 , 新潟 , 5/28-5/31
4 . Kawasaki, T.,Saito, K.,Mitsui, K.,Ikawa, M.,Yamashita, M.,Tanaiguchi, Y.,Takeda,
S.,Mitani, K.,Sakai, N. 「 Introduction of a foreign gene with mammalian adenovirus into fish
cells 」, 第41回発生生物学会 , 新潟 , 5/28-5/31
5 . 酒井則良,河崎敏広,斉藤憲二,新屋みのり 「 ゼブラフィッシュ精原幹細胞の培養と精子への分化 」, 第15回小型魚類研究会 , 名古屋 , 9/12-9/13
6 . 河崎敏広,新屋みのり,斉藤憲二,酒井則良 「 精巣細胞の再集合－皮下移植によるゼブラ
フィッシュ精原幹細胞の増殖と精子形成 」, 第80回日本動物学会 , 静岡 , 9/17-9/20
7 . Kawasaki, T.,Saito, K.,Shinya, M.,Sakai, N. 「 Production of progenies from cultured
spermatogonial stem cells in zebrafish 」, 第32会日本分子生物学会 , 横浜 , 12/9-12/12
8 . Saito, K.,Siegfrid, K.R., Nusslein-Volhard, C.,Sakai, N. 「 New ENU-induced zebrafish
mutants with phenotypes of male infertility and meiotic arrest 」, 第32会日本分子生物学会 ,横浜 , 12/9-12/12
9 . Shinya, M.,Kobayashi, K.,Masuda, A.,Tokumoto, M.,Ozaki, Y.,Kawasaki, T.,Sado,
Y.,Saito, K.,Sakai, N. 「 The development of gene-knockdown system using RNAinterference in zebrafish 」, 第32回日本分子生物学会年会 , 横浜 , 12/9-12
10 . 新屋みのり 「 小型魚類を用いた量的形質遺伝子座解析～個体差を解析する～ 」, 日本

発生生物学会秋季シンポジウム , 三島 , 11/27-29
11 . 新屋みのり 「 メダカを用いた頭蓋顔面形態の遺伝学的解析 」, 第81回日本遺伝学会年会 , 松本 , 9/16-18
12 . 新屋みのり 「 魚類頭部形態の定量と遺伝学的解析 」, 定量生物学の会遺伝研キャラバ
ン , 三島 , 3/13-14
BOOK
1 . 新屋みのり,酒井則良 ( 2009 ) メダカ・ゼブラフィッシュ 身近な動物を使った実験 13 30
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F. GENETIC STRAINS RESEARCH CENTER
F-e. Plant Genetics Laboratory
F. GENETIC STRAINS RESEARCH CENTER
F-e. Plant Genetics Laboratory
Nori Kurata
RESEARCH ACTIVITIESPUBLICATIONSPapers
1 . Fujisawa, H., Horiuchi, Y., Harushima, Y., Takada, T., Eguchi, S., Mochizuki, T.,
Sakaguchi, T., Shiroishi, T., Kurata, N. ( 2009 ) SNEP: Simultaneous detection of
nucleotide and expression polymorphisms using Affymetrix GeneChip ,BMC
Bioinformatics , 10 , 131 - 0
2 . Tsuda, K., Ito, Y., Yamaki, S., Miyao, A., Hirochika, H., Kurata, N. ( 2009 ) Isolation andmapping of three rice mutants that showed ectopic expression of KNOX genes in leaves ,Plant Science , 177 , 131 - 135
3 . 奥野員敏, 倉田のり ( 2009 ) 動植物育種の到達点と目標 , 育種学研究 , 11 , 107 107
4 . Win, KT., Kubo, T., Miyazaki, Y., Doi, K., Yamagata, Y., Yoshimura, A. ( 2009 )Identification of two loci causing F1 pollen sterility in inter-and intraspecific crosses of rice. ,Breeding Science , 59 , 411 - 418
5 . Takano-Kai N., Jiang H., Kubo T., Sweeney M., Matsumoto T., Kanamori H.,
Padhukasahasram B., Bustamante C., Yoshimura A., Doi K. and McCouch S. ( 2009 )Evolutionary History of GS3, a Gene Conferring Grain Length in Rice. , Genetics , 182 ,
1323 - 1343
6 . Kubo T. Yamagata Y, Eguchi M. and Yoshimura A. ( 2008 ) A novel epistatic interaction
at two loci causing hybrid male sterility in an inter-subspecific cross of rice (Oryza sativa L.).
, Genes Genet. Syst. , 83 , 443 - 453
POSTER PRESENTATIONS
1 . 倉田のり, 久保貴彦, 水多陽子, 新濱充, 藤田雅丈, 大柳一, 望月孝子, 春島嘉章 「Genetic and genomic analysis of factors consisting of reproductive barriers in rice 」, 第32回日本分子生物学会年会 ワークショップ3W6 ”Mechanisms for reproductive isolation andtheir relation to genome evolution” , 横浜市 , 12/9-12
2 . 守口和基, 枝廣憲孝, 池ケ谷洋佑, 白木英介, 田中克幸, 倉田のり, 鈴木克周 「 Ⅳ型分泌機構を応用した新規迅速遺伝子導入法の確立（Establishment of of a novel high-throughput
gene introduction system using bacterial Type IV secretion system.） 」, 第32回日本分子生物学会年会ワークショップ3W6 ”Mechanisms for reproductive isolation and their relation to
genome evolution” , 横浜市 , 12/9-12
3 . Kurata, N., Mizuta, Y., Kubo, T., Hrushima, Y. 「 Genome evolution and reproductive
barriers in rice 」, 6th International Rice Genetics symposium , Manila , 11/16-19
4 . Kurata, N. 「 Wild Rice Resource Project in Japan Its Perspectives 」, 6th International
Rice Genetics symposium , Manila , 11/16-19

5 . 水多陽子、春島嘉章、倉田のり 「 イネ亜種間交雑において生殖的隔離を引き起こす相互作用遺伝子座DOPPELGANGER1と2の単離・解析 」, 日本遺伝学会第81回大会 , 松本市 ,9/16-186 . 春島嘉章、栗木哲、水多陽子、倉田のり 「 F2集団を使った配偶体または接合体内の２遺伝子座間の相互作用による生殖的隔離の検出 」, 日本育種学会第116回講演会 , 札幌市 ,9/24-26
7 . Win, KT., Kubo, T., Miyazaki, Y., Doi, K., Yamagata, Y., Yasui, H., Yoshimura, A. 「Molecular mapping of two loci conferring F1 pollen sterility in inter- and intraspecific crossesof rice. 」, 6th International Rice Genetics symposium , Manila , 11/16-19
8 . 野々村賢一, 中野睦子, 福地佐斗志, 永口貢, 宮尾安藝雄, 廣近洋彦 「 減数分裂の進行に必須のイネMEL2遺伝子はイネ科植物で保存されている 」, 日本育種学会第116回講演会 ,札幌市 , 9/25-26
9 . 濱田和輝, 菊地俊介, 望月孝子, 倉田のり, 矢野健太郎 「 イネの大規模な遺伝子発現デー
タに基づく発現制御ネットワーク構築 」, 日本育種学会第116回講演会 , 札幌市 , 9/25-26
10 . Fujisawa, H., Horiuchi, Y., Harushima, Y., Takada, T., Eguchi, S., Mochizuki, T.,
Sakaguchi, T., Kawakita, M., Shiroishi, T., Kurata, N. 「 Statistical Analysis of Affymetrix
GeneChip Data 」, TRIC Symposium "Statistical and Systems Genetics" , 三島 , 10/22
11 . Harushima, Y., Kuriki, S., Fujisawa, H., Kurata, N. 「 Detection of interactive pairs of
qeproductive barriers using F2 population 」, TRIC Symposium "Statistical and Systems
Genetics" , 三島 , 10/23
12 . 倉田のり, 久保貴彦, 水多陽子, 山木辰一郎, 堀内陽子, 春島嘉章 「 野生イネ種間、種内変異とゲノム機能分化 」, 日本遺伝学会第81回大会 , 松本市 , 9/16-18
13 . 濱田和輝, 菊地俊介, 本郷耕平, 望月孝子, 倉田のり, 矢野健太郎 「 イネの大規模な遺伝
子発現データに基づく発現制御ネットワーク構築 」, 第32回日本分子生物学会年会 , 横浜市, 12/9-12
14 . 永田俊文, 神沼英里, 大柳一, 望月孝子, 中村保一, 会津智幸, 藤山秋佐夫, 豊田敦, 倉田
のり 「 次世代高速シークエンサーを用いた近縁イネゲノム配列データの評価 」, 第32回日本
分子生物学会年会 , 横浜市 , 12/9-12
15 . 藤田雅丈, 堀内陽子, 上田弥生, 水多陽子, 久保貴彦, 矢野健太郎, 山木辰一郎, 津田勝利, 新濱充, 加藤大貴, 菊地俊介, 濱田和輝, 望月孝子, 堤伸浩, 倉田のり 「 イネ全生殖過程における遺伝子発現解析を用いた多様な因子の補足 」, 第32回日本分子生物学会年会 , 横浜
市 , 12/9-12
16 . 守口和基, 枝廣憲孝, 池ケ谷洋佑, 白木英介, 田中克幸, 倉田のり, 鈴木克周 「 Ⅳ型分泌機構を応用した新規迅速遺伝子導入法の確立 」, 第32回日本分子生物学会年会 , 横浜市 ,12/9-1217 .
水多陽子, 春島嘉章, 倉田のり
「 イネ亜種間交雑で生殖的隔離を引き起こす
DOPPELGANGER1(DPL1)とDPL2の単離・解析 」, 第32回日本分子生物学会年会 , 横浜
市 , 12/9-12
18 . 上田健治、渡部奈穂美、高橋幸子、宮尾安藝雄、廣近洋彦、野々村賢一、倉田のり、我彦廣悦、井上正保 「 イネ花粉突然変異体Tos0445の単離と解析 」, 日本植物学会第73回大会 , 山形市 , 9/17-20
19 . 山木辰一郎、倉田のり、野々村賢一 「 イネの胚珠分化に異常を示すosmads13変異体の解析 」, 日本育種学会第116回講演会 , 札幌市 , 9/24-26
20 .
堀内陽子、春島嘉章、望月孝子、藤澤洋徳、川喜田雅則、江口真透、倉田のり「
Affimetrix Rice Genome Arrayを用いたSFP検出とゲノム多様性解析への利用 」, 日本育種学会第116回講演会 , 札幌市 , 9/24-26
21 . 鷹野典子、H. Jiang、久保貴彦、松本隆、金森裕之、S. McCouch、吉村淳、土井一行 「イネの種子長に関する遺伝子座GS3の多様性 」, 日本育種学会第116回講演会 , 札幌市 ,9/24-26
22 . 久保貴彦、春島嘉章、水多陽子、倉田のり 「 イネ亜種間交雑で分離の歪みを示すゲノム領域の検出 」, 日本育種学会第115回講演会 , つくば市 , 3/26-28
23 . 山木辰一郎、宮林登志江、永口貢、野々村賢一、倉田のり 「 野生イネの穂にみる分枝パターンの多様性 」, 日本育種学会第115回講演会 , つくば市 , 3/26-28
24 . 久保貴彦、山形悦透、江口真紀、吉村淳 「 イネのF1花粉不稔遺伝子S24に相互作用する遺伝子座S35 」, 日本育種学会第115回講演会 , つくば市 , 3/26-28
25 . 新濱充、春島嘉章、倉田のり 「 日本晴とKinandang putiとの交雑で見られる生殖隔離遺伝子座のマッピング 」, 日本育種学会第115回講演会 , つくば市 , 3/26-28

26 . 藤田雅丈、堀内陽子、上田弥生、水多陽子、久保貴彦、矢野健太郎、山木辰一郎、津田
勝利、新浜充、加藤大貴、菊地俊介、濱田和輝、望月孝子、堤伸浩、倉田のり 「 イネ全生殖過程における遺伝子発現解析を用いた多様な因子の捕捉 」, 日本育種学会第115回講演会 ,つくば市 , 3/26-28
27 . 石川亮, 永口貢, 新崎由紀, 倉田のり, 木下哲 「 栽培イネと野生イネの種間交雑にみられる胚乳発生異常の原因 」, 第50回 日本植物生理学会年会 , 名古屋 , 3/21-24
28 . 保浦徳昇，諏訪部圭太，安益公一郎，鈴木剛，矢野健太郎，石水毅，高橋宏和，中園幹生，長村吉晃，倉田のり，渡辺正夫，松岡信，堤伸浩 「 イネの雄性配偶子とタペータム細胞でのトランスクリプトーム解析 」, 第50回 日本植物生理学会年会 , 名古屋 , 3/21-24
EDUCATION
1 . 倉田のり
科学研究費特定領域研究「植物の生殖過程におけるゲノム障壁」班会議 東京 7/7-8
2 . 長戸康郎、倉田のり イネ研究の多様性と展望 国立遺伝学研究所研究会 三島 10/3031
BOOK
1 . 倉田のり, 野々村賢一 ( 2009 ) イネ 遺伝子資源・ゲノムリソースの現状と展望 バイオリ
ソース＆データベース活用術（細胞工学別冊） 190 - 192
OTHERS1 . 倉田のり , 1 , 日本育種学会副会長
2 . 水多陽子, 春島嘉章, 倉田のり , 2 , 日本遺伝学会第８1回大会Best Paper賞
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F. GENETIC STRAINS RESEARCH CENTER
F-f. Microbial Genetics Laboratory
F. GENETIC STRAINS RESEARCH CENTER
F-f. Microbial Genetics Laboratory
Hironori Niki
RESEARCH ACTIVITIESPUBLICATIONSPapers
1 . 波田野俊之,仁木 宏典 ( 2009 ) バクテリアの染色体分配の普遍性と多様性 , 蛋白質核酸酵素3月増刊 , 54 , 409 - 415
2 . Furuya, K., and NIKI, H. ( 2009 ) Isolation of heterothallic haploid and auxotrophic
mutants of Schizosaccharomyces japonicus. , Yeast , 26 , 221 - 233
3 . Shiomi, D., Mori, H., and Niki, H. ( 2009 ) Genetic mechanism regulating bacterial cell
shape and metabolism , Communicative & Integrative Biology , 2 , 219 - 220
4 . 仁木宏典 ( 2009 ) バクテリアの形態はどのようにして決まるのか？ , 化学と生物 , 47 ,831 - 837
5 . 塩見 大輔、仁木 宏典 ( 2009 ) 細胞骨格蛋白質による大腸菌尾形態形成機構 , 日本
微生物形態学会誌 , 24 , 51 - 60
6 . 仁木 宏典 ( 2007 ) バクテリアのセントロメア様領域 , 実験医学 , 25 , 114 - 118
POSTER PRESENTATIONS
1 . 塩見大輔,仁木宏典 「 Global regulatory network among proteins that determine cell
shape in E. coli. 」, 第32回日本分子生物学会年会 , 横浜 , 12/11
2 . Niki, H. 「 Contribution of formation of the Ter domain for proper segregation of bacterial
nucleoids 」, Gordon Research Conference, 'Chromosome Dynamics' , Lucca (Barga), Italy, 24/5
3 . Niki, H. 「 A Gene Network of Morphogenesis in the Rod-Shaped Bacterium 」, the2009 EMBO workshop 'Frontiers of Bacterial Cell Biology' , Oxford, UK , 24/8
4 . Niki, H. 「 CHK1 DEPENDENT TRANSITION OF YEAST GROWTH TO HYPHALGROWTH IN SCHIZOSACCHAROMYCES JAPONICUS 」, The 5th International Fission
Yeast Meeting, Pombe 2009 , Tokyo , 26/10
5 . Niki, H. 「 CHK1 DEPENDENT TRANSITION OF YEAST GROWTH TO HYPHALGROWTH IN SCHIZOSACCHAROMYCES JAPONICUS 」, The 5th International Fission
Yeast Meeting, Pombe 2009 , Tokyo , 26
6 . Niki, H. 「 National BioResource Project - Japan of Prokaryotes 」, the First Asian
Chapter Meeting of ISBER and Asian Network for Research Resource Center (ANRRC) ,Seoul, Korea , 22/9
7 . Niki, H. 「 National BioResource Project - Japan of Prokaryotes 」, the First Asian
Chapter Meeting of ISBER and Asian Network for Research Resource Center (ANRRC) ,Seoul, Korea , 22
8 . Niki, H. 「 CHK1 DEPENDENT TRANSITION OF YEAST GROWTH TO HYPHALGROWTH IN SCHIZOSACCHAROMYCES JAPONICUS 」, The International Symposium

on "Chromosome cycle and genome dynamics" , 那須町 栃木県 , 10/11
9 . 仁木 宏典 「 ジャポニカス分裂酵母（Schizosachharomyces japonicus）の
少し変わった細胞増殖メカニズム 」, 第68回酵母研究会 , 京都 , 13/3
10 . 田口温子, 仁木宏典 「 大規模な逆位による染色体再編を利用した染色体機能領域の解
析 」, 第6回21世紀大腸菌研究会 , 静岡県熱海市 , 6/11-6/12
11 . AOKI, K.,FURUYA, K., and NIKI, H. 「 'SEMI-OPEN MITOSIS': NUCLEAR ENVELOPE
WAS TORN OFF UPON NUCLEAR DIVISION IN Schizosaccharomyces japonicus 」, The
5th International Fission Yeast meeting , Tokyo , 10/26-31
12 . 塩見大輔 「 細胞骨格タンパク質RodZの抑制変異解析から見た形態形成の制御の遺伝
子ネットワーク 」, 第6回21世紀大腸菌研究会 , 熱海市 , 6/11-12
13 . 塩見大輔,AOKI, Keita.,仁木宏典 「 B. sunbtilis knockout strains by the National
BioResource Project in Japan 」, 5th Conference on Functional Genomics of Gram-positive
Microorganisms, 15th International Conference on Bacilli , San Diego, CA USA , 6/14-18
14 . 塩見大輔,境雅子、仁木宏典 「 桿菌の形を決める新規の細胞骨格性タンパク質 」, 細菌
学会 , 名古屋 , 03/13
EDUCATION
1 . 仁木 宏典

第6回 21世紀大腸菌研究会 熱海 11/6

BOOK
1 . 柳原克彦、仁木 宏典 ( 2009 ) 原核生物の遺伝要素 分子生物学イラストレイテッド 改訂第3版 75 - 90
2 . 青木敬太、仁木宏典 ( 2009 ) 染色体の分配とM期制御 蛋白質核酸酵素3月増刊
406 - 408back

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F. GENETIC STRAINS RESEARCH CENTER
F-g. Invertebrate Genetics Laboratory
F. GENETIC STRAINS RESEARCH CENTER
F-g. Invertebrate Genetics Laboratory
Ryu Ueda
RESEARCH ACTIVITIESPUBLICATIONSPapers
1 . Umemori, M., Habara, O., Iwata, T., Maeda, K., Nishinoue, K., Okabe, A., Takemura, M.,
Takahashi, K., Saigo, K., Ueda, R., and Adachi-Yamada, T. ( 2008 ) RNAi-MediatedKnockdown Showing Impaired Cell Survival in Drosophila Wing Imaginal Disc. , Gene
Regulation and Systems Biology , 3 , 11 - 20
2 . Wu, Y., Brock, A. R., Wang, Y., Fujitani, K., Ueda, R. and Galko, M. J. ( 2009 ) A BloodBorne PDGF/VEGF-like Ligand Initiates Wound-Induced Epidermal Cell Migration in
Drosophila Larvae. , Curr. Biol. , 19 , 1 - 5
3 . Abe, M., Setoguchi, Y., Tanaka, T., Awano, W., Takahashi, K., Ueda, R., Nakamura, A.
and Goto, S. ( 2009 ) Membrane Protein Location-Dependent Regulation by PI3K (III) andRabenosyn-5 in Drosophila Wing Cells. , PLoS ONE , 4 , 0 - 0
4 . Kanie, M., Yamamoto-Hino, M., Karino, Y., Nishihara, S., Ueda, R., Goto, S. and Kanie,
O. ( 2009 ) Insight into the Regulation of Glycan Synthesis in Drosophila Chaoptin Basedon Mass Spectrometry. , PLoS ONE , 4 , 0 - 0
POSTER PRESENTATIONS
1 . 青山尚規，田村郁雄，小山啓太，勝田江朗，上田龍，山口（武井）ゆき，渡辺晃，北田祐介，多羽田哲也，松野健治 「 RNA干渉法を用いたショウジョウバエNotchの細胞内小胞輸送に関する遺伝子の網羅的探索 」, 第３２回日本分子生物学会年会 , 横浜市 , 12/11
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G. CENTER FOR GENETIC RESOURCE INFORMATION
G-a. Genetic Informatics Laboratory
G. CENTER FOR GENETIC RESOURCE INFORMATION
G-a. Genetic Informatics Laboratory
Yukiko Yamazaki
RESEARCH ACTIVITIESPUBLICATIONSPapers1.
Sato,K.,Shini,T.,Seki,M.,Shinozaki,K.,Yoshida,H.,Takeda,K.,Yamazaki,Y.,Conte,M.,Kohara,Y. ( 2009 )Development of 5006 Full-Length CDNAs in Barley: A Tool for Accessing Cereal Genomics
Resources. , DNA Res. , 16 , 81 - 89
2 . Yukiko Yamazaki,Sugawara, H. ( 2009 ) National BioResource Project Information
Center , Exp. Anim. , 58 , 75 - 84
POSTER PRESENTATIONS
1 . Kimura, G.,Sakaniwa, S.,Yamakawa, T.,Yamazaki, Y. 「 "Bioresourceworld" as a
Biological Resources Portal 」, Plant & Animal Genomes XVII Conference , San Diego ,1/10-14
2 . Yamazaki, Y.,Tsuchiya, R., Asanuma, T., Shidahara, Y. and Sakaniwa, S. 「 Direct
submission system and literature annotation of rice genes in Oryzabase 」, Biocuration2009 , Berlin , 4/17-20
3 . 山崎由紀子 「 ナショナルバイオリソースプロジェクト情報整備プログラムの成果と展望 」,
統合データベースプロジェクトシンポジウム , 東京 , 6/12
4 . Yamazaki, Y. 「 Bioresource databases in Japan(tmp) 」, ANNRRC Meeting , ソウル ,9/22-25
5 . 山崎由紀子 「 植物バイオリソース情報-整備状況と利用方法について- 」, 新しい作物科学を支えるバイオリソース , つくば , 3/28
6 . Tsuchiya, R.,Yamazaki, Y. 「 CMAP(tmp) 」, 育種学会研究集会 , 札幌 , 11/25
7 . 山崎由紀子 「 NBRP(tmp) 」, 情報・システム研究機構シンポジウム , 東京 , 11/30
BOOK
1 . 山崎由紀子 ( 2009 ) バイオリソース（生物遺伝資源）情報センター 細胞工学：バイオリ
ソース＆データベース活用術 256 - 259
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G. CENTER FOR GENETIC RESOURCE INFORMATION
G-b. Genome biology Laboratory
G. CENTER FOR GENETIC RESOURCE INFORMATION
G-b. Genome biology Laboratory
Yuji Kohara
RESEARCH ACTIVITIESPUBLICATIONSPapers
1 . Langenhan T, Promel S, Mestek L, Esmaeili B, Waller-Evans H, Hennig C, Kohara Y,
Avery L, Vakonakis I, Schnabel R, Russ AP. ( 2009 ) Latrophilin signaling links anteriorposterior tissue polarity and oriented cell divisions in the C. elegans embryo. ,Developmental Cell , 17 , 494 - 504
2 . Hashimoto H, Miyamoto R, Watanabe N, Shiba D, Ozato K, Inoue C, Kubo Y, Koga A,
Jindo T, Narita T, Naruse K, Ohishi K, Nogata K, Shin-I T, Asakawa S, Shimizu N, Miyamoto
T, Mochizuki T, Yokoyama T, Hori H, Takeda H, Kohara Y, Wakamatsu Y. ( 2009 )Polycystic kidney disease in the medaka (Oryzias latipes) pc mutant caused by a mutationin the Gli-Similar3 (glis3) gene. , PLoS One , 4 , e6299 3 . Wang X, Zhao Y, Wong K, Ehlers P, Kohara Y, Jones SJ, Marra MA, Holt RA, Moerman
DG, Hansen D. ( 2009 ) Identification of genes expressed in the hermaphrodite germ lineof C. elegans using SAGE. , BMC Genomics , 9 , 213 4 . Kawano T, Zheng H, Merz DC, Kohara Y, Tamai KK, Nishiwaki K, Culotti JG. ( 2009 )C. elegans mig-6 encodes papilin isoforms that affect distinct aspects of DTC migration,and interacts genetically with mig-17 and collagen IV. , Development , 136 , 1433 - 1442
5 . Sato K, Shin-I T, Seki M, Shinozaki K, Yoshida H, Takeda K, Yamazaki Y, Conte M,
Kohara Y. ( 2009 ) Development of 5006 full-length CDNAs in barley: a tool for accessing
cereal genomics resources. , DNA RESEARCH , 16 , 81 - 89
6 . McGhee JD, Fukushige T, Krause MW, Minnema SE, Goszczynski B, Gaudet J, Kohara
Y, Bossinger O, Zhao Y, Khattra J, Hirst M, Jones SJ, Marra MA, Ruzanov P, Warner A,
Zapf R, Moerman DG, Kalb JM. ( 2008 ) ELT-2 is the predominant transcription factor
controlling differentiation and function of the C. elegans intestine, from embryo to adult. ,Developmental Biology , 327 , 551 - 565
7 . Kobayashi N, Watanabe M, Horiike T, Kohara Y, Okada N. ( 2009 ) Extensive analysisof EST sequences reveals that all cichlid species in Lake Victoria share almost identicaltranscript sets. , Gene , 442 , 187 - 191
8 . Sasaki S, Mello CC, Shimada A, Nakatani Y, Hashimoto S, Ogawa M, Matsushima K,
Gu SG, Kasahara M, Ahsan B, Sasaki A, Saito T, Suzuki Y, Sugano S, Kohara Y, Takeda
H, Fire A, Morishita S. ( 2008 ) Chromatin-associated periodicity in genetic variation
downstream of transcriptional start sites. , Science , 323 , 401 - 404
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G. CENTER FOR GENETIC RESOURCE INFORMATION
G-c. Comparative Genomics Laboratory
G. CENTER FOR GENETIC RESOURCE INFORMATION
G-c. Comparative Genomics Laboratory
Asao Fujiyama
RESEARCH ACTIVITIESPUBLICATIONSPapers
1 . Dang. Z., Yagi, K., Oku, Y., Kouguchi, H., Kajino, K., Watanabe, J., Matsumoto, J.,
Nakao, R., Wakaguri, H., Toyoda, A. and Sugimoto, C. ( 2009 ) Evaluation of
Echinococcus multilocularis tetraspanins as vaccine candidates against primary alveolar
echinococcosis. , Vaccine , 27 , 7339 - 7345
2 . Goto, H., Watanabe, K., Araragi, N., Kageyama, R., Tanaka, K., Kuroki, Y., Toyoda, A.,
Hattori, M., Sakaki, Y., Fujiyama, A., Fukumaki, Y. and Shibata, H. ( 2009 ) The
identification and functional implications of human-specific "fixed" amino acid substitutionsin the glutamate receptor family. , BMC Evol Biol. , 9 , 224 - 224
3 . Kawaura, K., Mochida, K., Enju, A., Totoki, Y., Toyoda, A., Sakaki, Y., Kai, C., Kawai, J.,
Hayashizaki, Y., Seki, M., Shinozaki, K., and Ogihara, Y. ( 2009 ) Assessment of adaptive
evolution between wheat and rice as deduced from the full-length cDNA sequence data andthe expression patterns of common wheat. , BMC Genomics , 10 , 271 - 271
4 . Iida, K., Fukami-Kobayashi, K., Toyoda, A., Sakaki, Y., Kobayashi, M., Seki, M., andShinozaki, K. ( 2009 ) Analysis of Multiple Occurrences of Alternative Splicing Events in
Arabidopsis thaliana Using Novel Sequenced Full-Length cDNAs. , DNA Res. , 16 , 155 164
5 . Mitsui,J., Mizuta, I., Toyoda, A., Ashida, R., Takahashi, Y., Goto, J., Fukuda, Y., Date, H.,
Iwata, A., Yamamoto, M., Hattori, N., Murata, M., Toda, T. and Tsuji, S. ( 2009 ) Mutations
for Gaucher disease confer high susceptibility to Parkinson disease. , Arch Neurol. , 66 ,
571 - 576
POSTER PRESENTATIONS
1 . 藤山秋佐夫,豊田敦,黒木陽子 「 次世代シーケンシングがもたらす比較ゲノム研究の進展」, 第３２回分子生物学会年会 , 横浜市 , 12/9-12
2 . 黒川顕,森宙史,堂園亜由美,丸山史人,加藤広海,大坪嘉行,豊田敦,藤山秋佐夫,津田雅孝「 新型シークエンサーによるメタゲノム解析 」, 第32回分子生物学会年会 , 横浜市 , 12/9-12
3 . Suzuki, T., Ueda, H., Yano, T., Okada, S., Terajima, ., Mitsuyama, T., Toyoda, A.,
Fujiyama, A., Kawabata, ah., Sakurai, M., 「 A landscape of A-to-l RNA editing in humantranscriptome: a hidden layer of gene expression produced by qualitative information
embedded in RNA molecules. 」, 第32回分子生物学会年会 , 横浜市 , 12/9-12
4 . Kunieda, T., Kuwahara, H., Horikawa, D., Toyoda, A., Kaytayama, T., Arakawa, K.,
Yamaguchi, A., Shin-I, T., Onishi, K., Motoyama, A., Aizu, T, Hasebe, Y., kido, N., kanehisa,M., kubo, T., Kohara, Y, Fujiyama, A. 「 Genome analysis and functional proteomics ofanhydrobiotic extremotolerant tardigrade Ramazzottius cf. varieornatus 」, 第32回分子生物学会年会 , 横浜市 , 12/9-12
5 . Nagata, T., kaminuma, E., Ohyanagi, H., Mochizuki, T., Nakamura, Y., Aizu, T., Fujiyama,A., Toyoda, A., Kurata, N. 「 The evaluation of the closely related rice genome arrangement
data which analyzed with a next generation high-speed sequencer. 」, 第32回分子生物学会
年会 , 横浜市 , 12/9-12
6 . Yamaguchi, A., Kuwahara, h., Ohmi, S., Horikawa, D., Toyoda, A., katayama, T.,
Arakawa, K., Fujiyama, A., Kubo, T., Kunieda, T., 「 The analysis of anti-aggregation
proteins from tardigrades with desiccation tolerance. 」, 第32回分子生物学会年会 , 横浜市, 12/9-12
7 . Shang, W., Hori, T., Toyoda, A., Fujiyama, A., Fukagawa, T. 「 Characterization ofchiken centromere DNA 」, 第32回分子生物学会年会 , 横浜市 , 12/9-12
8 . Masuzaki, S., Yamasaki, T., Kujime, Y., Kishikawa, S., Nakade, K., Yoshiki A., Abe, K.,
Toyoda, A., Murata, T., Obata, Y. 「 Consolidation of DNA resource infrastructure in the
RIKEN BioResource Center: Construction of a BAC library derived from a mouse strain
C57BL/6N. 」, 第32回分子生物学会年会 , 横浜市 , 12/9-12
9 . Kubo, T., Yamato, K., Yamano, T., Satake, T., Suzuki. Y., Sugano, S., Fujiyama, A.,
Kohara, Y., Toyoda, A., Shin-I, t., Kuroki, Y., Itoh, T., Taniguchi, T., FukazawaH. 「ChlamyBase, Chlamydomonas genome database based on the genomic resources ofmatingtype minus strain and transcriptome data obtained by massively paralleledsequencing. 」, 第32回分子生物学会年会 , 横浜市 , 12/9-12
10 . Kuroki, Y., Toyoda, A., Kondo, S., Nishida, Y., Ebata, T., Shin-I, T., Kohara, Y.,
Fujiyama, A. 「 Comparative analysis of the Y chromosomes to understand the malespecific character in mammalian genome evolution. 」, 第32回分子生物学会年会 , 横浜市, 12/9-12
11 . Nishida, Y., Kondo, S., Kuroki, Y., Toyoda, A., Fujiyama, A. 「 Construction
bioinfomatics analysis pipeline of the resequencing data with next generation seqencer. 」,
第32回分子生物学会年会 , 横浜市 , 12/9-12
12 . katayama, T., Arakawa, K., Hasebe, Y., Kido, N., Kunieda, T., Toyoda, A., Shin-I, T.,
Horikawa, D., Kuwahara, H., Onishi, K., Motoyama, A., Aizu, T., Kanehisa, M., Kohara, Y.,
Fujiyama, A. 「 Construction of the genome database and draft sequence analysis ofanhydrobiotoc extremotolerant tadigrade. 」, 第32回分子生物学会年会 , 横浜市 , 12/9-12
13 . Watanabe, T., Chuma, S., Totoki, Y., Toyoda, A., Yamamoto, Y., Hoki, Y., Fujiyama, A.,
Shibata, T., Nakatsuji, N., Sado, T., Sasaki, H. 「 Zucchini is a mitochndorial protein
required for spermatogenesis and piRNA biogenesis in mouse. 」, 第32回分子生物学会年
会 , 横浜市 , 12/9-12
14 . Kuma, K., Noguchi, H., Komoda, T., Kobayashi, S., Taniguchi, T., Ito, T., Araki, J.,Fujiyama, A. 「 The genome viewer displaying unified data from multiple genome
databases. 」, 第32回分子生物学会年会 , 横浜市 , 12/9-12
15 . 豊田 敦 「 ラットゲノム研究：SNP解析と次世代シークエンサー 」, 第2回ラットリソースリ
サーチ研究会 , 京都 , 1/30
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H. STRUCTURAL BIOLOGY CENTER
H-a. Biological Macromolecules
H. STRUCTURAL BIOLOGY CENTER
H-a. Biological Macromolecules
Kazuhiro Maeshima
RESEARCH ACTIVITIESPUBLICATIONSPapers
1 . Nishino, Y., Takahashi, Y., Imamoto, N., Ishikawa, T., and Maeshima, K. ( 2009 ) Threedimensional visualization of a human chromosome using coherent X-ray diffraction ,Physical Review Letters , 102 , 018101 2 . Maeshima, K. and Nishino, Y. ( 2009 ) Three-Dimensional Visualization of a Human
Chromosome Using Coherent X-ray. Diffraction. , Spring-8 Research Frontiers , , 46 47
3 . Nishino, Y., Takahashi, Y., Kubo, H., Furukawa, H., Yamauchi, K., Maeshima,K., Imamoto, N., Hirohata, R., Matsubara, E., and Ishikawa, T. ( 2009 ) Nanostructure
analysis by coherent hard X-ray diffraction. , J Phys , 186 , 012056 4 . Takemoto, A., Maeshima, K., Ikehara, T., Yamaguchi, K., Murayama, A., Imamura, S.,
Imamoto, N., Yokoyama, S., Hirano, T., Watanabe, Y., Hanaoka, F., Yanagisawa, J.,
Kimura, K. ( 2009 ) The chromosomal association of condensin II is regulated by anoncatalytic function of PP2A. , Nat Struct Mol Biol , 13 , 1302 - 1308
ORAL PRESENTATION
1 . 12/3-12/5 12/3-12/5 理研セミナー 和光 3/24
POSTER PRESENTATIONS
1 . Kazuhiro Maeshima 「 How Is Genome DNA Compacted into a Mitotic Chromosome?
」, The 9th NIBB-EMBL Symposium Functional Imaging from Atoms to Organisms ,Okazaki , 4/20-4/22
2 . Kazuhiro Maeshima 「 Mitotic chromosome structure: irregular folding of nucleosome
fibers 」, 17th International Chromosome Conference Boone , NC, USA , 6/23-6/26
3 . 前島一博 「 放射光によるバイオイメージング：その可能性と未来 」, SPring-8次期計画
2019シンホシウム~光科学の明日~ , 東京 , 6/19
4 . 前島一博 「 核内と分裂期染色体内のglobalなクロマチン構造 」, 第82回日本生化学会年会シンポジウム「クロマチン生物学の近未来」 , , 10/23
5 . 前島一博 「 核内と分裂期染色体内のglobalなクロマチン構造 」, 第32回日本分子生物学会年会ワークショップ クロマチン機能構造の階層性 , , 12/12
6 . 白 燦基, 今本 尚子, 金城 政孝, 「 蛍光相関分光法で生細胞の分裂期染色体内部を見る」, 第32回日本分子生物学会 , 神奈川県 ,BOOK1 . 前島一博、 西野吉則 ( 2009 ) コヒーレントX線回折によるヒト染色体構造の３次元観察
生物物理 298 - 300
2 . 日原さえら、前島一博 ( 2009 ) 分裂期染色体の構築原理 実験医学増刊 細胞核－遺伝情報制御と疾患 43 - 51back

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H. STRUCTURAL BIOLOGY CENTER
H-b. Molecular Biomechanism Laboratory
H. STRUCTURAL BIOLOGY CENTER
H-b. Molecular Biomechanism Laboratory
Nobuo Shimamoto
RESEARCH ACTIVITIESPUBLICATIONSPapers
1 . 嶋本伸雄, 中村 史, 青木幸広, 鹿田真一, 山田貴壽, 雨宮陽介, 畠山明子, 藤森直治 (2009 ) ダイヤモンドナノ針ーナノ細胞マッピングに向けた取り組みー , ニューダイヤモンド, 94 , 23 - 29
2 . Amemiya, Y., Hatakeyama, A., and Shimamoto, N. ( 2008 ) Aminosilane Multilayer
Formed on Single-Crystalline Diamond Surface with Controlled Nanoscopic Hardness andBioactivity by Wet Process , Langmuir , 25 , 203 - 209
POSTER PRESENTATIONS
1 . 嶋本伸雄 「 Asian and Oceanian Conference of Transcription 」, Sokendai International
symposium 2009 , 神奈川県三浦郡葉山町 , 12/14〜17
2 . 嶋本伸雄、中山秀喜 「 ナノバイオロジーのパワーを基礎生物学で引き出す条件 」, 第32回分子生物学会年会 , 横浜市 , 12/9〜12
3 . 今清水正彦、嶋本伸雄 「 ピロリン酸による転写のproofreading 」, 第32回分子生物学会
年会 , 横浜市 , 12/9〜12
4 . 中山秀喜、嶋本伸雄 「 tmRNAによる定常期の維持 」, 第32回分子生物学会年会 , 横浜
市 , 12/9〜12
5 . 藤田龍介、嶋本伸雄 「 機能的SELEXを用いた大腸菌ゲノム内のプロモーター配列の解析 」, 第32回分子生物学会年会 , 横浜市 , 12/9〜12
6 . 畠山明子、雨宮陽介、今清水正彦、中山秀喜、嶋本伸雄 「 ナノ電極を用いた単一細胞への電気的物質導入 」, 第32回分子生物学会年会 , 横浜市 , 12/9〜12
7 . 今清水正彦、嶋本伸雄 「 ピロリン酸による転写のproofreading 」, ラン藻の分子生物学
2009 , 木更津市 , 12/4 〜5
8 . 嶋本伸雄、中山秀喜 「 ナノバイオロジーで何がわかるか 翻訳機構と大腸菌の定常期適応 」, 日本動物学会 第80回大会 2009静岡 , 静岡市 , 9/17〜20
9 . 中山秀喜、嶋本伸雄、伊藤耕一 「 Translation cycle とリボソーム休眠 」, 第6回21世紀大腸菌研究会 , 熱海市 , 6/11〜12
10 . 中山秀喜、嶋本伸雄、伊藤耕一 「 Translation cycle とリボソーム休眠 」, 第11回RNAミーティング , 新潟市 , 7/27〜29
11 . 今清水正彦、嶋本伸雄 「 転写のproofreading機構 」, 第6回21世紀大腸菌研究会 , 熱
海市 , 6/11〜12
12 . Madhura Raghavan、嶋本伸雄、中山秀喜 「 大腸菌の増殖の不均一性 」, 第6回21世紀大腸菌研究会 , 熱海市 , 6/11〜12
13 . 今清水正彦、嶋本伸雄 「 シアノバクテリアと大腸菌RNA polymerasesの機能比較から見る転写のfidelity維持機構 」, 第3回日本ゲノム微生物学会 , 東京都 , 3/5〜7

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H. STRUCTURAL BIOLOGY CENTER
H-d. Biomolecular Structure Laboratory
H. STRUCTURAL BIOLOGY CENTER
H-d. Biomolecular Structure Laboratory
Yasuo Shirakihara
RESEARCH ACTIVITIESPOSTER PRESENTATIONS
1 . Shirakihara, Y.,Tanikawa, H.,Yoshimune,K., Murakami S., Suzuki T., Yoshida M. 「Crystallization of ATPsynthase 」, 生物物理47回年会 , 徳島 , 10/30~11/1
2 . Itou, H.,Watanabe, N.,Yao, M.,Shirakihara, Y.,Tanaka, I. 「 C.glutamicum由来多剤調節因子CgmRの構造学的研究：多剤耐性に適したもうひとつのリプレッサーの作用機構 」, 日本蛋
白質科学会2009年年会 , 熊本県、熊本市 , 5/20-22
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H. STRUCTURAL BIOLOGY CENTER
H-e. Gene Network Laboratory
H. STRUCTURAL BIOLOGY CENTER
H-e. Gene Network Laboratory
Emiko Suzuki
RESEARCH ACTIVITIESPUBLICATIONSPapers
1 . Kurusu,M.,Maruyama,Y.,Adachi,Y.,Okabe,M.,Suzuki,E.,and Katsuo Furukubo-Tokunaga. ( 2008 ) Aconserved nuclear receptor,Tailless,is required for efficient proliferation and prolonged maintenance ofmushroom body progenitors in the Drosophila brain , Developmental Biology , 326 , 224 - 236
2.
Sone,M.,Uchida,A.,Komatsu,A.,Suzuki,E,Ibuki,IAsada,M.,Shiwaku,H.,Tamura,T.,Hoshino,M.,Okazawa,H.,andNabeshima,Y. ( 2008 ) Loss of yata,a Novel Gene Regulating the Subcellular Localization of APPL,Induces
Deterioration of Neural Tissues and Lifespan Shortening , PLoS ONE , 4 , 1 - 19
3 . Hong,W.,Zhu,H.,Potter,C.,Barsh,G.,Kurusu,M.,Zinn,K.,and Luo,L. ( 2009 ) Leucine-rich repeat
transmembrane proteins instruct discrete dendrite targeting in an olfactory map , Nature Neuroscience ,12 , 1542 - 1551
4 . Furukubo-Tokunaga,K., Adachi,Y., Kurusu,M., and Walldorf,U. ( 2009 ) Brain patterning defects caused
by mutations of the twin of eyeless gene in Drosophila melanogaster. , Fly(Austin) , 3 , 263 - 269
POSTER PRESENTATIONS
1 . 鈴木えみ子 「 Summer Research Program for Undergraduate Students,NIGINTERN 」, SOKENDAIINTERNATIONAL SYMPOSIUM 2009 , 神奈川県葉山町 , 12/14~12/17
2 .
Nakayana,M.,Okuda,T.,Fujisawa,N.,Kono,N.,Arai,H.,Suzuki,E.,Ishikawa,H.,and Matsuno,K.
「 A
Drosophila model of peroxisome disease revealed an essential role of peroxisome in male-specific meiosis」, 日本発生生物学会 第42回大会 , 新潟 , 5/28～5/31
3 . Nakayama,M.,Okuda,T.,Fujisawa,N.,Kono,N.,Arai,H.,Suzuki,E.,Umeda,M.,Ishikawa,H.,and Matsuno,K. 「A Drosophila model of peroxisome disease revealed an essential role of peroxisome in male-specific germ
cell maturation 」, The 9th Japanese Drosophila Research Conference , 嬬恋 , 7/6～7/8
4 . Kurusu,M.,Zinn,K.,and Suzuki,E. 「 N-Cadherin regulates birth order-dependent axonal fasciculation,axon
growth,and dendritic terminal morphology during the development of Drosophila mushroom body. 」, The 9th
Japanese Drosophila Research Conference , 嬬恋 , 7/6
5 . Yasunaga,K.,Suzuki,E.,and Emoto,K. 「 Dendrite rearrangement in adult Drosophila sensory neurons 」,
The 9th Japanese Drosophila Research Conference , 嬬恋 , 7/6～7/8
6 . Kurusu,M.,Zinn,K.,and Suzuki,E. 「 Spatiotemporal change in the expression of cell-adhesion moleculeduring neural differentiation is crucial for the neural circuit formation. 」, 第32回日本分子生物学会年会 , 横浜
, 12/9～12/12
7 . 中山実、奥田貴之、藤澤奈穂、河野望、新井洋由、鈴木えみ子、梅田真郷、石川裕之、松野健治 「 ショウジ
ョウバエをモデル系としたペルオキシソーム形成異常症の病態研究 」, 第32回日本分子生物学会年会 , 横浜 ,12/9～12/12
8 . 安永桂一郎、金森崇浩、鈴木えみ子、榎本和生 「 ショウジョウバエ成虫期における感覚ニューロン樹状突起
構造の再編 」, 第32回日本分子生物学会年会 , 横浜 , 12/9～12/12
OTHERS
1 . 鈴木えみ子 , 1 , 第３２回日本分子生物学会年会組織委員
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I. CENTER FOR INFORMATION BIOLOGY AND DNA DATA BANK OF JAPANI-a. Laboratory for DNA Data Analysis
I. CENTER FOR INFORMATION BIOLOGY AND DNA DATA BANK OF JAPANI-a. Laboratory for DNA Data Analysis
Takashi Gojobori
RESEARCH ACTIVITIESPUBLICATIONSPapers
1 . 五條堀 孝 ( 2009 ) 進化の大樹のてっぺんから、私たちを知る , Someone [サムワン], 10 , 20 - 21
2 . Clemente, JC., Ikeo, K., Valiente, G., Gojobori, T. ( 2009 ) Optimized ancestral state
reconstruction using Sankoff parsimony , BMC Bioinformatics , 10 , 1 - 27
3 . Suzuki, H., Gojobori, T., Ikeo, K., Sera, M., Kawai, J. and 156 authors. ( 2009 ) The
transcriptional network that controls growth arrest and differentiation in a human myeloid
leukemia cell line , Nature Genetics , 41 , 553 - 562
4 . Abdu, M., Ahmed, I., Brahmachari, S., Gojobori, T., Liu, E., Sugano, S., Suzuki, Y.,
Tokunaga, K., Zilfalil, B.A. and 85 authors. ( 2009 ) Mapping Human Genetic Diversity in
Asia , Science , 326 , 1541 - 1545
5 . Fukuchi, S., Homma, K., Sakamoto, S., Sugawara, H., Tateno, Y., Gojobori, T. andNishikawa, K. ( 2009 ) The GTOP database in 2009: updated content and novel features
to expand and deepen insights into protein structures and functions. , Nucleic Acids Res.
, 37 , 333 - 337
6 . Shimada, MK., Matsumoto, R., Hayakawa, Y., Sanbonmatsu, R., Gough, C., YamaguchiKabata, Y., Yamasaki, C., Imanishi, T. and Gojobori, T. ( 2009 ) VarySysDB: a human
genetic polymorphism database based on all H-InvDB transcripts. , Nucleic Acids Res. ,37 , 810 - 815
7 . Komiyama, T., Kobayashi, H., Tateno, Y., Inoko, H., Gojobori, T. and Ikeo, K.. ( 2009 )An evolutionary origin and selection process of goldfish. , GENE , 430 , 5 - 11
8 . Uehara, S., Izumi, Y., Kubo, Y., Wang, CC., Mineta, K., Ikeo, K., Gojobori, T., Tachibana,M., Kikuchi, T., Kobayashi, T., Shibahara, S., Taya, C., Yonekawa, H., Shiroishi, T. andYamamoto, H. ( 2009 ) Specific expression of Gsta4 in mouse cochlear melanocytes: anovel role for hearing and melanocyte differentiation. , Pigment Cell Melanoma Res. , 22
, 111 - 119
9 . Sugawara, H., Ikeo, K., Fukuchi, S., Gojobori, T. and Tateno, Y. ( 2009 ) DDBJ dealing
with mass data produced by the second generation sequencer. , Nucleic Acids Res. , 37
, 16 - 18
10 . Jin, L., Kryukov, K., Suzuki, Y., Imanishi, T., Ikeo, K. and Gojobori, T. ( 2009 ) The
evolutionary study of small RNA-directed gene silencing pathways by investigating RNase III
enzymes. , GENE , 435 , 1 - 8
11 . Mano, S., Endo, T., Oka, A., Ozawa, A., Gojobori, T., Inoko, H. ( 2009 ) Detecting
linkage between a trait and a marker in a random mating population without pedigre record, PLos One , 4 , 4956 - 0

12 . Fukuchi, S., Homma, K., Minezaki, Y., Gojobori, T., Nishikawa, K.. ( 2009 )Development of an accurate classification system of proteins into structured andunstructured regions that uncovers novel structural domains: its application to humantranscription factors. , BMC Structural Biology , 9 , 1 - 31
13 . Liu, QX., Hiramoto, M, Ueda, H., Gojobori, T., Hiromi, Y., and Hirose, S. ( 2009 )Midline governs axon pathfinding by coordinating expression of two major guidancesystems , Genes & Development , 23 , 1165 - 1170
14 . Suzuki, Y., Gojobori, T., Kumar, S. ( 2009 ) Methods for incorporating thehypermutability of CpG dinucleotides in detecting natural selection operating at the aminoacid sequence level , Mol Biol Evol. , 26 , 2275 - 2284
15 . Kawahara, Y., Sakate, R., Matsuya, A., Murakami, K., Sato, Y., Zhang, H., Gojobori T.,
Itoh, T., and Imanishi, T. ( 2009 ) G-compass: A Web-based comparative genome browser
between human and other vertebrate species , Bioinformatics. , 25 , 3321 - 3322
16 . 五條堀孝、金城その子、Jose C. Clemente、池尾一穂 ( 2009 ) 超高速シークエンス時
代のデータベース戦略 , 実験医学 , 27 , 32 - 37
17 . 林崎良英、八尾徹、五條堀孝 ( 2009 ) 次世代シーケンサーは生命科学に新たな”革命”をもたらす , 科学２ , 79 , 231 - 244
18 . 五條堀孝 ( 2009 ) ”宝”が眠る進化研究最前線 , 月刊「公明」 , 3 , 42 - 47
19 . 池尾一穂、五條堀孝 ( 2009 ) ダーウィンをみつめて , Someone [サムワン] , 7 , 13 15
20 . 瀬名秀明、五條堀孝 ( 2009 ) 人類はミュータントXとスパイダーマンを誕生させることができるか , Back Up （バックアップ） , 28 , 10 - 15
21 . 五條堀孝 ( 2009 ) 木村資生が残した宿題 分子進化の中立説４０年 , 総研大ジャーナ
ル春号 , 15 , 20 - 21
22 . 五條堀孝 ( 2009 ) [特集]国立遺伝学研究所６０年の歩みを映して DDBJ事業 , 生物の科学 遺伝 , 60 , 86 - 90
23 . 五條堀孝、山内一也 ( 2009 ) 細胞とウイルスの境界線 『現代科学も決して作れない"超精密機械"細胞のすべて』 , ニュートンムック , , 136 - 141
24 . 館野義男、古江基樹、五條堀孝 ( 2009 ) 「パーソナルゲノム時代の創薬」『次世代創薬
テクノロジー 実践：インシリコ創薬の最前線』 , 遺伝子医学MOOK 14 , , 175 - 179
ORAL PRESENTATION
1 . Takashi Gojobori “The entire distribution of TSS (Transcription Start Sites) in thehuman genome and it’s evolutionary implication to non-coding RNAs” Seminar at Stazione
Zoologica Anton Dohrn Stazione Zoologica Anton Dohrn (Naples, Italy) 4/30
2 . 五條堀 孝 「生命と知能の進化」 慶応義塾大学湘南藤沢キャンパス 10/27
3 . 五條堀 孝 「ペタゲノミクスの時代を迎えて-超大量な生命情報への将来戦略」 先端生命科学研究会 慶応義塾大学湘南藤沢キャンパス 10/27
4 . Takashi Gojobori “Evolution of the Central Nervous System from the viewpoint ofComparative Genomics” NCKU, National Cheng Kung University, (Tainan, ROC) 11/12
5 . Takashi Gojobori “Evolution of Camera Eye from the viewpoint of Comparative Gene
Expressionics” NTU, National Taiwan University (Taiwan, ROC) 11/13
POSTER PRESENTATIONS
1 . 五條堀 孝 「 ゲノムネットワーク時代の生命医科学 」, 第5回ゲノムネットワークプロジェク
ト公開シンポジウム「ゲノムネットワークが拓く新しい医学・生物学」 , 東京 , 1/16
2 . 五條堀 孝 「 「肝炎ウイルス・データベースの構築と宿主ファクターの研究応用」 」, 厚生労働科研費4班合同班会議 , 東京 , 2/7
3 . Takashi Gojobori 「 “Hinv database and Genome Network Project” 」, Korea-ChinaJapan Bioinformatics Training Course , Kyoto , 2/27
4 . 五條堀 孝 「 「バイオ研究開発の最前線と情報戦略 」, 平成20年度富士山麓エリア都市
エリア産学官連携促進事業成果発表会 , 静岡県沼津市 , 3/11
5 . Takashi Gojobori 「 “Biomolecular information infrastructure in Japan and its global
collaborations” 」, ELIXIR WP3 Global Committee meeting , Hinxton, United Kingdom ,4/28

6 . Takashi Gojobori 「 “Is Darwinian evolution the impetus of species differences in the
genome network system?” 」, IUBS-UNESCO Symposium “Basic Issues in Evolution” ,Venice, Italy , 5/3
7 . Takashi Gojobori 「 「創立60周年の歩み」 」, 遺伝研60周年記念事業記念講演会 , 静岡
県三島市 , 6/1
8 . Takashi Gojobori 「 “Evolution of the Central Nervous System: Comparative Gene
Expressionics Approach” 」, Albany 2009 , Albany, N.Y., USA , 6/18
9 . 五條堀 孝 「 「遺伝学から見る新型インフルエンザ」 」, 医看工総会 , 静岡県三島市 ,6/22
10 . 五條堀 孝 「 「データ解析拠点の構築と情報研究開発」 」, セルイノベーションプログラムとPDPOとシーケンス拠点、データ解析拠点との打合せ , 東京 , 6/30
11 . 五條堀 孝 「 「データ解析拠点の構築と情報研究開発」 」, セルイノベーションキックオフ
ミーティング , 東京 , 7/27
12 . 五條堀 孝 「 「シーケンス革命を見据えた海洋ゲノム研究開発の将来」 」, シンポジウム「海洋ゲノム情報を活用した革新的食料生産技術の開発」 , 東京 , 8/18
13 . 五條堀 孝 「 「ゲノムからみた脳・神経系の起源と進化」 」, ダーウィン生誕200年記念公開シンポジウム , 東京 , 8/22
14 . 五條堀 孝 「 「病態のシステム的理解と疾患情報モデルの構築」 」, 平成21年度第2回
企画委員会 , 兵庫県神戸市 , 9/1
15 . 五條堀 孝 「 「次世代シーケンサー時代のデータベース」 」, 日本遺伝学会第81回大会 ,長野県松本市 , 9/16
16 . 五條堀 孝 「 「遺伝学会用語集委員会新設の経緯と趣旨」 」, 日本遺伝学会第81回大会 , 長野県松本市 , 9/17
17 . 五條堀 孝 「 “Human Genome Network” 」, JST-ETHZ Workshop on Molecular
Medical Research , 東京 , 9/22
18 . 五條堀 孝 「 「ペタゲノミクスの到来-生命情報の超大量時代をどう乗り越えるか」 」,
GCOE若手支援シンポジウム , 北海道札幌市 , 9/30
19 . Takashi Gojobori 「 “The Perspectives of Evolutionary Genomics: “Sequencing
Revolution” and its Implications in Evolutionary Studies”（Video Presentationにて参加） 」,
Darwin200 Human Evolution Symposium （Meeting devoted to the 150th of the Origin ofSpecies） , Bellville, Cape Town, South Africa , 10/12
20 . 五條堀 孝 「 「肝臓病：トランスレーショナル・リサーチへのゲノム情報戦略」 “LIVERDISEASE: Strategic approach of genomic information to translational research” 」, 日本肝臓学会大会 , 京都府 , 10/15
21 . Takashi Gojobori 「 "確認中”（Video Presentationで講演-現地参加はなし） 」, Rap 6
Workshop , Manila, Philippines , 11/15
22 . Takashi Gojobori 「 ”Introduction to International databases” 」, 日本肝臓学会The 8thSingle Topic Conference “HBV Now in Asia” & Special Hands-on Seminar “How to Master
Bioinformatics of Hepetitis Viruses Using International Databases” , 東京 , 11/23
23 . 五條堀 孝 「 「ライフサイエンスの研究開発におけるオミックス研究の重要性」 」, 木原財団研究開発事業成果報告会2009 , 神奈川県横浜市 , 11/25
24 . 五條堀 孝 「 「眼の起源と進化～われわれはどうして光を見ることができるようになったのか」 」, 浜松コンファレンス , 静岡県浜松市 , 11/29
25 . 五條堀 孝 「 「共同利用としてのライフサイエンス基盤-日本DNAデータバンク（DDBJ）とライフサイエンス統合データベース（LSDB） 」, 公開シンポジウム「情報とシステム2009-科学と文化の基盤：大学と育むデータベース-」 , 東京都 , 11/30
26 . 五條堀 孝 「 「病態のシステム的理解と疾患情報モデルの構築」 」, 応用ゲノムCO1、
CO2班会議 , 東京都 , 12/2
27 . 五條堀 孝 「 「パーソナルゲノム時代におけるDNA鑑定の今後」 」, DNA鑑定学会学術大会 , 神奈川県横浜市 , 12/9
28 . Takashi Gojobori 「 “An evolutionary process of the central nervous system from theviewpoint of comparative gene expressionics” 」, 第32回日本分子生物学会 , 神奈川県横浜市 , 12/11
EDUCATION
1 . 五條堀 孝

国立遺伝学研究所研究会「パーソナルゲノム時代のヒトゲノム多様性研究－

シーケンス革命とゲノム解析-」 静岡県三島市 1/23
2 . 五條堀 孝
経産省統合データベースプロジェクト第2回運営委員会 東京都江東区
2/23
3 . 五條堀 孝 バチカン市国大使上野景文様講演会 静岡県三島市 2/26
4 . JST, CIB-DDBJ, NIG, KOBIC, KRIBB,SCBIT
Korea-China-Japan Bioinformatics
Training Course・& Symposium 京都府 2/25-28
5 . 五條堀 孝「生命情報科学若手の会」設立および第1回研究会 静岡県三島市 4/2526
6 . 国立遺伝学研究所 遺伝研60周年記念事業式典、記念講演会 静岡県三島市 6/1
7 . 日本学術会議基礎生物学委員会、応用生物学委員会合同進化・系統学分科会 （運営委
員長：五條堀 孝） ダーウィン生誕200年記念公開シンポジウム 東京都 8/22
8 . 五條堀 孝 （理事長） DNA鑑定学会学術大会 神奈川県横浜市 12/9
9 . 五條堀孝、佐藤矩行、池尾一穂
International Symposium Marine Genomics 沖縄県
那覇市 12/15-18
10 . 遺伝学普及会 市民公開講演会 静岡県三島市 9/19
BOOK
1 . John M. Butler（著） 福島弘文、五條堀 孝［監訳］ 藤宮仁、玉田一生、福間義也、長崎華奈子［訳］ ( 2009 ) DNA鑑定とタイピング Forensic DNA Typing (Biology, Technology,
and Genetics of STR Markers) 0 - 0
2 . 斎藤成也、藤博幸、小林一三、川島武士、佐藤矩行、植田信太郎、五條堀 孝 ( 2009 )進化学と生命情報 シリーズ進化学 ② 遺伝子とゲノムの進化 239 - 258
3 . 五條堀 孝 ( 2009 ) 生命情報のデータベース化 理科年表2010 904 - 0
4 . Gojobori, T., Ikeo, K.. and Hwang, JS. ( 2009 ) The evolutionary origin and process ofthe central nervous system: Comparative genomics approach Scientific Insights Into the
Evolution of the Universe and of Life 321 - 336
5 . Gojobori, T., Nakagawa, S. and Clemente, JC. ( 2009 ) DNA sequence analysis(Version 2.0) Encyclopedia of Life Sciences 1 - 9
6 . John M. Butler（著） 福島弘文、五條堀 孝［監訳］ 藤宮仁、玉田一生、福間義也、長崎華奈子［訳］ ( 2009 ) 遺伝学・データベース・計測技術・データ検証・品質管理 DNA鑑定とタイ
ピング 0 - 0
7 . 斎藤成也、藤博幸、小林一三、川島武士、佐藤矩行、植田信太郎、五條堀孝 ( 2009 ) 進
化学と生命情報 シリーズ進化学 ② 遺伝子とゲノムの進化 239 - 258
8 . 五條堀孝他 ( 2009 ) 生命情報のデータベース化 理科年表2010 904 - 0
PATENT1 . 2009-042148 , 生命現象予測装置、生命現象予測方法、および生命現象予測プログラム, 紺野剛史 宮本青 池尾一穂 , 富士通株式会社 大学共同利用機関法人情報・システム研
究機構
OTHERS
1 . 五條堀 孝 , 1 , Editor of FEBS Letters
2 . 五條堀 孝 , 1 , Editor of GENE
3 . 五條堀 孝 , 1 , Founding Editor of Genome Biology and Evolution
4 . 五條堀 孝 , 1 , Associate Editor of Molecular Biology and Evolution
5 . 五條堀 孝 , 1 , Associate Editor of PLoS Genetics
6 . 五條堀 孝 , 1 , Editorial Board of Investigative Genetics
7 . 五條堀 孝 , 1 , Editorial Board of Genome Medicine
8 . 五條堀 孝 , 1 , Editorial Board of OMICS A Journal of Integrative Biology
9 . 五條堀 孝 , 1 , Editorial Board of Gene Therapy and Molecular Biology
10 . 五條堀 孝 , 1 , Editorial Board of BMC Genomics
11 . 五條堀 孝 , 2 , 紫綬褒章受章
12 . 五條堀 孝 , 1 , 日本遺伝学会会長
13 . 五條堀 孝 , 1 , 日本組織適合性学会理事

14 . 五條堀 孝 , 1 , DNA鑑定学理事長
15 . 五條堀 孝 , 1 , 遺伝学普及会常務理事
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I. CENTER FOR INFORMATION BIOLOGY AND DNA DATA BANK OF JAPANI-b. Laboratory for Gene-Product Informatics
I. CENTER FOR INFORMATION BIOLOGY AND DNA DATA BANK OF JAPANI-b. Laboratory for Gene-Product Informatics
Yasukazu Nakamura
RESEARCH ACTIVITIESPUBLICATIONSPapers
1 . Ikeda S, Kaneko T, Okubo T, Rallos LE, Eda S, Mitsui H, Sato S, Nakamura Y, Tabata
S, Minamisawa K. ( 2009 ) Development of a bacterial cell enrichment method and its
application to the community analysis in soybean stems. , Microb Ecol. , 58 , 703 - 714
2 . Hakoyama T, Niimi K, Watanabe H, Tabata R, Matsubara J, Sato S, Nakamura Y,
Tabata S, Jichun L, Matsumoto T, Tatsumi K, Nomura M, Tajima S, Ishizaka M, Yano K,
Imaizumi-Anraku H, Kawaguchi M, Kouchi H, Suganuma N. ( 2009 ) Host plant genome
overcomes the lack of a bacterial gene for symbiotic nitrogen fixation. , Nature , 462 , 514- 517
3 . Kurihara, Y., Kaminuma, E., Matsui, A., Kawashima, M., Tanaka, M., Morosawa, T.,
Ishida, J., Mochizuki, Y., Shinozaki, K., Toyoda, T., Seki, M. ( 2009 ) Transcriptome
Analyses Revealed Diverse Expression Changes in ago1 and hyl1 Arabidopsis Mutants ,Plant and Cell Physiology , 50 , 1715 - 1717
4 . Kurihara, Y., Matsui, A., Hanada, K., Kawashima, M., Ishida, J., Morosawa, T., Tanaka,
M., Kaminuma, E., Mochizuki, Y., Matsushima, A., Toyoda, T., Shinozaki, K. and Seki, M. (2009 ) Genome-wide suppression of aberrant mRNA-like noncoding RNAs by NMD in
Arabidopsis. , Proc. Natl. Acad. Sci. USA , 106 , 2453 - 2458
ORAL PRESENTATION
1 . 神沼英里 Short Readデータ解析例の紹介 ライフサイエンス統合データベースセンター(DBCLS) セミナー DBCLS 8/4
2 . 児玉悠一 DDBJ Read Archive 理化学研究所 横浜研究所 所内セミナー 理化学研究
所 横浜研究所 8/6
3 . 李慶範 遺伝子データバンクについて（DNA Data Bank of Japan, DDBJ） Korean
Bioinformation Center (KOBIC) セミナー 韓国・KOBIC 8/19
4 . 児玉悠一 DDBJ Read Archive 第23回システムバイオロジー研究会 東京大学医科学研究所 6/26
5 . 児玉悠一, 猿橋智, 五條堀孝, 舘野義男, 中村保一, 菅原秀明, 次世代シークエンサの出力データのためのアーカイブについて 第4回遺伝学研究所内部交流セミナー 遺伝学研究所
5/26
6 . Eli Kaminuma, Yasukazu Nakamura, Toshihisa Takagi Constructing a high-throughput
annotation pipeline of next generation sequenceing reads 第4回遺伝学研究所内部交流セ
ミナー 遺伝学研究所 5/26
7 . 真島淳, 中村保一 DDBJ: 配列データのフロー ライフサイエンス統合データベースセンター(DBCLS) セミナー DBCLS

8 . 神沼英里, 児玉悠一, 望月孝子, 猿橋智, 中村保一 DDBJにおける次世代シーケンサデー
タへの対応 ライフサイエンス統合データベースセンター(DBCLS) セミナー DBCLS
9 . 児玉悠一 次世代シーケンサーデータのDRA(DDBJ Read Archive)への登録 理化学研究所 横浜研究所 第1回シーケンサー利用技術講習会 12/17
POSTER PRESENTATIONS
1 . 児玉悠一, 猿橋智, 五條堀孝, 舘野義男, 中村保一, 菅原秀明 「 次世代シークエンサの出力データのためのアーカイブについて 」, 統合データベースプロジェクト シンポジウム 2009 ,東京 , 6/12
2 . Hidemasa Bono, Eli Kaminuma, Yuichi Kodama, Yasukazu Nakamura, Kousaku Okubo,
Toshihisa Takagi 「 Systematic Organization of Gene Expression Data in Japan 」, 12th
International MGED Meeting , Phoenix, USA , 10/5-8
3 . 猿橋智、児玉悠一、神沼英里、五條堀孝、舘野義男、中村保一、菅原秀明 「 DDBJ Read
Archiveのご紹介（新型シークエサへの対応） 」,
バイオインフォマティクス推進センター事業（BIRD）第5回研究開発成果報告会 , ,4 . 神沼英里, 中村保一 「 DNA Data Bank of Japan (DDBJ) の新展開 」, 情報・システム研究機構シンポジム「情報とシステム2009」 , ,5 . Takehide Kosuge, Yasumasa Shigemoto, Yoshikazu Kuwana, Hideaki Sugawara, 「Consecutive Update of the Microbial Genome Re-Annotation Database, GTPS, 」, The 20th
International Conference on Genome Informatics , Tokyo , 12/14-16
6 . Eli Kaminuma, Yuichi Kodama, Satoshi Saruhashi, Takeshi Konno, Takako Mochizuki,
Hidemasa Bono, Hideaki Sugawara, Kousaku Okubo, Toshihisa Takagi, Yasukazu
Nakamura, 「 The 20th International Conference on Genome Informatics 」, The 20th
International Conference on Genome Informatics , 東京 , 12/14-16
7 . 児玉悠一, 猿橋智, 五條堀孝, 舘野義男, 神沼英里, 中村保一, 菅原秀明 「 「DDBJ Read
Archive」： 次世代シークエンサからの出力データのためのアーカイブ 」, 第32回日本分子生物学会年会 , 横浜 , 12/9-12
8 . 神沼英里,児玉悠一,大久保公策,高木利久,中村保一 「 次世代シークエンサーのハイスル
ープット・データ解析システム「DDBJ Short Read Annotation Pipeline」の構築 」, 第32回日本
分子生物学会年会 , 横浜 , 12/9-12
9 . 永田俊文,神沼英里,大柳一,望月孝子,中村保一,会津智幸,藤山秋佐夫,豊田敦,倉田のり 「次世代高速シークエンサーを用いた近縁イネゲノム配列データの評価 」, 第32回日本分子生物学会年会 , 横浜 , 12/9-12
10 . Eli Kaminuma, Toshifumi Nagata, Hajime Ohyanagi, Takako Mochizuki, Yasukazu
Nakamura, Tomoyuki Aizu, Asao Fujiyama, Atsushi Toyoda, Nori Kurata 「 Evaluation andefficiency of rice genome sequence reads from closely related species using the Next
Generation Sequencer 」, The 6 th International Rice Genetics Symposium , Manila ,11/15-19
11 . 中村保一，神沼英里，高木利久，大久保公策 「 DNA Data Bank of Japan (DDBJ) 」,
統合データベースプロジェクト シンポジウム 2009 , 東京 , 6/12
EDUCATION
1 . 中村保一

第21回 DDBJing講習会 in 三島 三島
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I. CENTER FOR INFORMATION BIOLOGY AND DNA DATA BANK OF JAPANI-c. Laboratory for Gene Function Research
I. CENTER FOR INFORMATION BIOLOGY AND DNA DATA BANK OF JAPANI-c. Laboratory for Gene Function Research
Yoshio Tateno
RESEARCH ACTIVITIESPUBLICATIONSPapers
1 . Sugawara, H., Ikeo, K., Fukuchi, S., Gojobori, T., Tateno, Y. ( 2008 ) DDBJ dealing withmass data produced by the second generation sequencer , Nucleic Acids Res , 37 , 16 18
2 . Fukuchi, S., Homma, K., Sakamoto, S., Sugawara, H., Tateno, Y., Gojobori, T.,
Nishikawa, K. ( 2008 ) The GTOP database in 2009: updated content and novel features
to expand and deepen insights into protein structures and functions. , Nucleic Acids Res.
, 37 , 333 - 337
3 . Horiike, T., Miyata, D., Hamada, K., Saruhashi, S., Shinozawa, T., Kumar, S.,
Chakraborty, R., Komiyama. T., Tateno, Y. ( 2008 ) Phylogenetic construction of 17
bacterial phyla by new method and carefully selected orthologs , Gene , 429 , 59 - 64back

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I. CENTER FOR INFORMATION BIOLOGY AND DNA DATA BANK OF JAPANI-e. Laboratory for Gene-Expression Analysis
I. CENTER FOR INFORMATION BIOLOGY AND DNA DATA BANK OF JAPANI-e. Laboratory for Gene-Expression Analysis
Kousaku Okubo
RESEARCH ACTIVITIESPUBLICATIONSPapers
1 . Ogasawara O. and Okubo K. ( 2009 ) On theoretical models of gene expression
evolution with random genetic drift and natural selection. , PLoS One. , , 0 - 0
ORAL PRESENTATION
1 . 大久保公策 「科学データは誰のものか」 統合データベース講習会 AJACSりんくう 大
阪府立大学 11/6
2 . 大久保公策 「アナトモグラフィー/BodyParts3Dの利用法」 統合データベース講習会
AJACS 本郷4 東京大学 4/17
POSTER PRESENTATIONS
1 . 大久保公策 「 「デジタル時代のジレンマ」フォーラム 」, 第３２回日本分子生物学会 , 横浜
市 , 12/10
2 . 大久保公策 「 「デジタル科学における独占と共有の賢いバランス」 」, 【CBRC】2009シンポジウム , 東京都 , 12/4
3 . 大久保公策 「 デジタル科学への最後のステップ 」, ﾗｲﾌｻｲｴﾝｽ統合ﾃﾞｰﾀﾍﾞｰｽｾﾝﾀｰ
2009ｼﾝﾎﾟｼﾞｳﾑ「科学における情報の上手な権利化と共有化」 , 東京都 , 10/5
4 . 大久保公策 「 先端技術と知財問題 」, 日本知財学会 第7回年次学術研究発表会 , 東京
都 , 6/14
5 . 大久保公策 「 「オープン科学に望まれる制度とは？」 」, 農芸化学会 , 福岡市 , 3/28
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J. CENTER FOR FRONTIER RESEARCH
J-c. Cell Architecture Laboratory
J. CENTER FOR FRONTIER RESEARCH
J-c. Cell Architecture Laboratory
Kimura Akatsuki
RESEARCH ACTIVITIESPUBLICATIONSPapers
1 . 木村暁 ( 2009 ) 細胞核の大きさと場所はどのように決まるのか？ , 実験医学（増刊） ,27 , 2779 - 2786
2 . Hara, Y., and Kimura, A. ( 2009 ) Cell-size-dependent spindle elongation in the
Caenorhabditis elegans early embryo , Current Biology , 19 , 1549 - 1554
ORAL PRESENTATION
1 . Kimura, A. 細胞内中心体配置の数理モデル構築と検証 第一回「光塾」 情報通信研究機構 神戸研究所 8/15
POSTER PRESENTATIONS
1 . Kimura, A. 「 シミュレーションを活用した線虫初期胚における細胞分裂の力学モデルの構
築 」, 日本発生生物学会秋季シンポジウム , 三島市 , 11/28
2 . Hara, Y. 「 細胞サイズに合わせた細胞内構造体のサイズ制御 」, 第一回「光塾」 , 神戸 ,8/15
3 . Kimura, A. 「 （非公開） 」, 第8回核ダイナミクス研究会 , 修善寺 , 6/20
4 . Hara, Y. 「 線虫C. elegans初期胚を用いた細胞サイズ依存的な紡錘体伸長制御機構の解析 」, 第8回核ダイナミクス研究会 , 修善寺 , 6/20
5 . Niwayama, R. 「 速度分布解析法・ＰＩＶ法とシミュレーション法・粒子法を用いた線虫初期胚の流動解析 」, 第8回核ダイナミクス研究会 , 修善寺 , 6/19
6 . Hayashi,H. 「 線虫初期胚を用いた核の大きさに影響する小胞体の構造的な役割 」, 第8回核ダイナミクス研究会 , 修善寺 , 6/19
7 . Kimura, K. 「 線虫C.elegansの初期胚における微小管とモータータンパク質に依存した核中心体複合体の中央配置機構の解析 」, 第8回核ダイナミクス研究会 , 修善寺 , 6/19
8 . Koyama, H. 「 細胞質分裂における細胞形状の測定とそれに基づいた理論モデル 」, 第8回核ダイナミクス研究会 , 修善寺 , 6/19
9 . Koyama, H. 「 細胞質分裂において収縮環と細胞表層の力学は何ができるのか～細胞形状の定量化とそれに基づいた数理モデル 」, 定量生物学の会・遺伝研キャラバン , 三島 ,3/14
10 . Kimura, K. 「 線虫C. elegansの初期胚における微小管とモータータンパク質に依存した中心体の中央配置機構の解析 」, 定量生物学の会・遺伝研キャラバン , 三島 , 3/13
11 . Niwayama, R. 「 quantification of cytoplasmic streaming and 3-dimensional
mechanical simulation for understanding of cytoplasmic rheology 」, 定量生物学の会・遺伝研キャラバン , 三島 , 3/13

12 . Hayashi,H. 「 C. elegans early embryoにおける核サイズの制御 」, 定量生物学の会・遺伝研キャラバン , 三島 , 3/13
13 . Hara, Y. 「 線虫初期胚を用いた細胞サイズ依存的な紡錘体伸長メカニズムの解析 」, 定
量生物学の会・遺伝研キャラバン , 三島 , 3/13
14 . Kimura, A. 「 細胞内空間配置のデジタル化とデジタル細胞を用いた仮説の検証 」, 定量
生物学の会第１回年会 , 東京 , 1/11
15 . Hara, Y. 「 細胞サイズによる細胞内構造体の大きさ制御機構の解析 」, 定量生物学の会
第１回年会 , 東京 , 1/11
16 . Koyama, H. 「 細胞質分裂における細胞形状の実験的・理論的解析 ～収縮環仮説と細胞表層メカニクス～ 」, 定量生物学の会第１回年会 , 東京 , 1/11
17 . Niwayama, R. 「 Elucidation of the physical property of the cytoplasm throughcomparison of in vivo flow dynamics with computer simulation 」, 定量生物学の会第１回年
会 , 東京 , 1/11
18 . Niwayama, R. 「 細胞質のレオロジーの理解のための線虫初期胚の細胞質流動の粒子
法シミュレーション 」, ソフトマター物理勉強会 , つくば , 9/2
19 . Niwayama, R. 「 線虫 C. elegans初期胚の細胞質流動の粒子法シミュレーションを通した細胞質のレオロジーの理解 」, 機械工学会計算力学講演会 , 金沢 , 10/12
20 . Kimura, A. 「 A model for cell-size-dependent spindle elongation in C. elegans embryo」, The 9th NIBB-EMBL Symposium “Functional Imaging from Atoms to Organisms” ,Okazaki , 4/21
21 . Kimura, K. 「 A tug-of-war model for the centrosome centering in Caenorhabditis
elegans early embryo 」, The 17th International C. elegans Meeting , Los Angeles, USA ,6/25
22 . Hara, Y. 「 Cell-size-dependent spindle elongation in the C. elegans early embryo 」,
The 17th International C. elegans Meeting , Los Angeles, USA , 6/25
23 . Koyama, H. 「 Quantification and theoretical analyses of cell shape predict novel rolesof cell surface and contractile ring in cytokinesis 」, The 17th International C. elegans
Meeting , Los Angeles, USA , 6/25
24 . Kimura, A. 「 細胞建築の力学的理解をめざして～線虫C. elegans初期胚を用いた紡錘
体伸長の解析～ 」, 第１９回日本数理生物学会年会 , 東京 , 9/9
25 . Kimura, A. 「 線虫初期胚における中心体配置のオルガネラ綱引きモデル 」, 日本遺伝学会第８１回大会 , 松本 , 9/18
26 . Koyama, H. 「 細胞質分裂のリポソームタイプの力学モデル：細胞分裂を促進する力学要素とは？ 」, 「細胞を創る」研究会 2.0 , 東京 , 10/2
27 . Hara, Y. 「 細胞サイズに合わせた細胞内構造体のサイズ制御 」, 「細胞を創る」研究会
2.0 , 東京 , 10/2
28 . Kimura, A. 「 線虫C. elegans胚を用いた細胞分裂のモデル構築 」, 第82回日本生化学会大会 , 神戸 , 10/21
29 . Niwayama, R. 「 Quantification and 3D simulation reconstruction of the cytoplasmic
streaming in C. elegans embryo to elucidate its mechanical basis 」, The 47th annual
meeting of the biophysical society of Japan , 徳島 , 10/30
30 . Kimura, A. 「 Construction of cell architecture models focusing on centrosome
positioning in C. elegans 」, Japanese Molecular Biology Pre-meeting Symposium 2009
‘Interface between Nano-biology and Molecular biology’ , 横浜 , 12/8
31 . Hayashi,H. 「 Live-cell imaging analysis of semi-open mitosis in C. elegans embryo 」,
The 32nd Annual Meeting of the Molecular Biology Society of Japan , 横浜 , 12/9
32 . Kimura, K. 「 Centrosome centering requires dynein-dependent movement of
intracellular organelles in C. elegans early embryo 」, The 32nd Annual Meeting of the
Molecular Biology Society of Japan , 横浜 , 12/9
33 . Koyama, H. 「 A physical model for cytokinesis based on cell-surface bending
elasticity in C. elegans embryonic cells 」, The 32nd Annual Meeting of the Molecular
Biology Society of Japan , 横浜 , 12/10
34 . Kimura, A. 「 線虫胚を用いた染色体の細胞内配置ダイナミクスのモデル構築 」, The
32nd Annual Meeting of the Molecular Biology Society of Japan , 横浜 , 12/10
35 . Hara, Y. 「 Cell-size-dependent control of spindle size in Caenorhabditis elegans early
embryo 」, The 32nd Annual Meeting of the Molecular Biology Society of Japan , 横浜 ,12/11

EDUCATION
1 . 木村暁、杉村薫 定量生物学の会第一回キャラバン 三島 3/13-14
2 . 原田昌彦、木村暁 第８回核ダイナミクス研究会 修善寺 6/18-20
3 . 藤森俊彦、木村暁 細胞の分裂・分化と高次生命現象 第82回日本生化学会大会シンポジウム 神戸 10/21
4 . 小布施力史、木村暁 遺伝情報場の構築とダイナミクスに迫る多角的アプローチ 第３２回
日本分子生物学会年会ワークショップ 横浜 12/10

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L. EXPERIMENTAL FARM
L. EXPERIMENTAL FARM
L. EXPERIMENTAL FARM
L. EXPERIMENTAL FARM
EXPERIMENTAL FARMRESEARCH ACTIVITIESPUBLICATIONSPapers
1 . Mang HG, Laluk KA, Parsons EP, Kosma DK, Cooper BR, Park HC, Abuqamar S,
Boccongelli C, Miyazaki S, Consiglio F, Chilosi G, Bohnert HJ, Bressan RA, Mengiste T
and Jenks MA ( 2009 ) The Arabidopsis RESURRECTION1 Gene Regulates a Novel
Antagonistic Interaction in Plant Defense to Biotrophs and Necrotrophs. , Plant physiolog, 151 , 290 - 305
2 . Miyazaki S, Murata T, Sakurai-Ozato N, Kubo M, Demura T, Fukuda H and Hasebe M (2009 ) ANXUR1 and 2, sister genes to FERONIA/SIRENE are male factors for coordinatedfertilization. , Current Biology:11 , 19 , 1327 - 1331
ORAL PRESENTATION
1 . 宮崎さおり Analysis of receptor-kinases related in reproduction mechanisms; ANXURI
and 2 are male factors controlling fertilization timing in Arabidopsis thaliana. GCOEセミナ
ー 奈良先端大学 バイオサイエンス学科 11/5
POSTER PRESENTATIONS
1 . 野々村賢一、高嶋和哉、永口貢、中野睦子、宮尾安藝雄、廣近洋彦、倉田のり 「 減数分裂への移行に必須であるイネ遺伝子の単離と機能解析 」, 日本育種学会第115回講演会 , つ
くば市 , 3/26-28
2 . 山木辰一郎、倉田のり、野々村賢一 「 イネの胚珠分化に異常を示すosmads13変異体の解析 」, 日本育種学会第116回講演会 育種学研究 , 札幌市 , 9/24-26
3 . Ken-Ichi Nonomura, Yayoi Ueda, Mitsugu Eiguchi, Akio Miyao, Hirohiko Hirochika, Nori
Kurata 「 Analysis of putative RNA-binding proteins promoting plant germ-cell development
in rice 」, 9th International Plant Molecular Biology Congress , St.Louis , 10/25-30
4 . Shinichiro Yamaki, Ken-Ichi Nonomura 「 What triggers the initiation of primordial plant
germ cells? 」, 32nd Annual Meeting of Molocular Biology Society of Japan , 横浜市 , 12/912
5 . Ken-Ichi Nonomura 「 Plant germ-cell development is supported by RNA-mediatedgenetic systems 」, The Opening Symposium of Plant Genomics and Breeding Institute ,Soeul , 9/11
6 . Ken-Ichi Nonomura 「 A rice gene regulating proper timing of the transition to meiosis 」,
China-Japan Rice Developmental Biology Meeting , Hangzhou , 10/9
7 . 野々村賢一 「 植物が減数分裂を同調化させるメカニズム 」, 第60回染色体学会年会 , 松
江市 , 11/13

8 . 野々村賢一、中野睦子、福地佐斗志、永口貢、宮尾安藝雄、廣近洋彦、倉田のり 「 減数分裂の進行に必須のイネMEL2遺伝子はイネ科植物で保存されている 」, 日本育種学会第116回講演会 育種学研究 , 札幌市 , 9/24-26
9 . 上田健治、渡部奈穂美、高橋幸子、宮尾安藝雄、廣近洋彦、野々村賢一、倉田のり、我彦
廣悦、井上正保 「 イネ花粉突然変異体Tos0445の単離と解析 」, 日本植物学会第73回大会, 山形市 , 9/17-20
10 . 野々村賢一、米田典央 「 植物生殖細胞の初期発生過程における染色体ダイナミックス」, 日本遺伝学会第81回大会 , 松本市 , 9/16-18
EDUCATION
1 . Nonomura, K.I., Araki, T. The mechanism of stem-cell maintenance and differentiation
during plant reproductive development Symposium, 32th Annual Meeting, The Molecular
Biology Society of Japan Yokohama 12/10
BOOK
1 . 米田典央、野々村賢一 ( 2009 ) 減数分裂：相方を探すための植物染色体のダイナミック
な挙動、特集「植物染色体の最前線」 生物の科学遺伝（5月号）特集I：植物染色体の最前線 63（3） 48 - 54
2 . 野々村賢一 ( 2009 ) 受粉と受精 種子の科学とバイオテクノロジー 13 - 16
3 . 倉田のり、野々村賢一 ( 2009 ) イネ 遺伝子資源・ゲノムリソースの現状と展望 バイオ
リソース＆データベース活用術（細胞工学別冊） 190 - 192
OTHERS
1 . 山木辰一郎、倉田のり、野々村賢一 , 2 , 第116回講演会に本育種学会優秀発表賞 「イネの胚珠分化に異常を示すosmads13変異体の解析」
2 . 野々村賢一、高嶋和哉、中野睦子、永口貢、宮尾安藝雄、廣近洋彦、倉田のり , 2 , 第115回講演会日本育種学会優秀発表賞 「減数分裂への移行に必須であるイネ遺伝子の単離と機能解析」
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N. TECHNICAL SECTION
N. Technical Section
N. TECHNICAL SECTION
N. Technical Section
Technical Section
RESEARCH ACTIVITIESPUBLICATIONSPapers
1 . Oishi, A., Gengyo-Ando, K., Mitani, S., Mohri-Shiomi, A., Kimura, KD., Katsura, I. (2009 ) FLR-2, the glycoprotein hormone alpha subunit, is involved in the neural control ofintestinal functions in Caenorhabditis elegans. , Genes to Cells , 14 , 1141 - 1154
2 . Ganley, A.R.D., Ide, S., Saka, K., and Kobayashi, T. ( 2009 ) The effect of replication
initiation on gene amplification in the rDNA and its relationship to aging , Mol. Cell , 35 ,683 - 693
OTHERS
1 . 谷田 勝教 , 2 , 文部科学大臣賞（平成21年度原子力・放射線安全管理功労表彰）
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No. 60back

Author Index
All 1 A B C D E F G H I J K L M N O P R S T U V W X Y Z
AuthorDivision/Laboratory
12/3-12/5
H-a Biological Macromolecules
156 authors.
I-a Laboratory for DNA Data Analysis
AOKI, K.
F-f Microbial Genetics Laboratory
Abe, G.
C-c Division of Molecular and Developmental Biology
Abe, K.
G-c Comparative Genomics Laboratory
Abe, M.
F-g Invertebrate Genetics Laboratory
Abuqamar S
L EXPERIMENTAL FARM
Adachi, N.
E-b Division of Agricultural Genetics
Adachi,N.
E-a Division of Human Genetics
Adachi,Y.
H-e Gene Network Laboratory
Agetsuma, M.
C-c Division of Molecular and Developmental Biology
Ahsan B
G-b Genome biology Laboratory
Aiba, A.
F-a Mammalian Genetics Laboratory
Aida, Y.
D-a Division of Population Genetics
Aiko Sada
F-b Mammalian Development Laboratory
Aiko Sada.
F-b Mammalian Development Laboratory
Ailani D.
C-a Division of Developmental Genetics
Ailani, D.
C-a Division of Developmental Genetics
Aizawa, H.
C-c Division of Molecular and Developmental Biology
Aizu, T
G-c Comparative Genomics Laboratory
Aizu, T.
G-c Comparative Genomics Laboratory
Akagi, T.
A-a Division of Molecular Genetics
Akio Miyao
L EXPERIMENTAL FARM
Amakawa,Y.
E-a Division of Human Genetics
Amano T.
F-a Mammalian Genetics Laboratory
Amano, M.
A-a Division of Molecular Genetics
Amano, T.
D-a Division of Population Genetics
F-a Mammalian Genetics Laboratory
Amemiya, Y.
H-b Molecular Biomechanism Laboratory
Aoki, T.
C-c Division of Molecular and Developmental Biology
Appelbaum, L.
C-c Division of Molecular and Developmental Biology
Arai,H.
H-e Gene Network Laboratory
Arakawa, K.
G-c Comparative Genomics Laboratory
Araki, H.
B-b Division of Microbial Genetics
Araki, J.

G-c Comparative Genomics Laboratory

Araki,H.
Aramaki, H.
Araragi, N.
Asakawa S
Asakawa, K.
Asanuma, T.
Asaoka, M.
Ashida, R.
Atsushi Suzuki
Atsushi Suzuki.
Avery L
Awano, W.
Azuma, M.
Backer, C.
Backer, C.B.
Baek, MW.
Ball, A.R. Jr.
Bao, Y.C.
Barsh,G.
Becker, T.S.
Behringer RR.
Benke,D.
Bergmann, J.H.
Bernauer, S.
Blizard, D.A.
Boccongelli C
Bohnert HJ
Boison,D.
Bossinger O
Bressan RA
Brock, A. R.
Brownfield L
Bubulya, P.A.
Bubulya,A.
Bubulya,P.
Bunai, F.
Bustamante C.
Catanesi, C.I.
Cavodeassi, F.
Chakraborty, R.
Charron, F.
Chattopadhyay,P.K.
Cheeseman, I.M.

B-b Division of Microbial Genetics
A-a Division of Molecular Genetics
G-c Comparative Genomics Laboratory
G-b Genome biology Laboratory
C-c Division of Molecular and Developmental Biology
G-a Genetic Informatics Laboratory
C-a Division of Developmental Genetics
G-c Comparative Genomics Laboratory
F-b Mammalian Development Laboratory
F-b Mammalian Development Laboratory
G-b Genome biology Laboratory
F-g Invertebrate Genetics Laboratory
E-c Division of Brain Function
A-a Division of Molecular Genetics
A-a Division of Molecular Genetics
C-c Division of Molecular and Developmental Biology
A-a Division of Molecular Genetics
A-a Division of Molecular Genetics
H-e Gene Network Laboratory
C-c Division of Molecular and Developmental Biology
F-b Mammalian Development Laboratory
C-b Division of Neurogenetics
A-a Division of Molecular Genetics
C-c Division of Molecular and Developmental Biology
F-c Mouse Genomics Resource Laboratory
L EXPERIMENTAL FARM
L EXPERIMENTAL FARM
C-b Division of Neurogenetics
G-b Genome biology Laboratory
L EXPERIMENTAL FARM
F-g Invertebrate Genetics Laboratory
E-b Division of Agricultural Genetics
E-b Division of Agricultural Genetics
E-b Division of Agricultural Genetics
E-b Division of Agricultural Genetics
A-a Division of Molecular Genetics
F-e Plant Genetics Laboratory
F-c Mouse Genomics Resource Laboratory
C-c Division of Molecular and Developmental Biology
I-c Laboratory for Gene Function Research
C-c Division of Molecular and Developmental Biology
D-a Division of Population Genetics
A-a Division of Molecular Genetics

Chen, G-D.
Chen, GD
Chen, GD.

C-c Division of Molecular and Developmental Biology
C-c Division of Molecular and Developmental Biology
C-c Division of Molecular and Developmental Biology

Chen, Y-C.
Chen, YC.
Cheng, C. H.
Cheng, CH.
Chilosi G
Chu, CY.
Chuma S.
Chuma, S.
Chuma,S.
Chumak N
Clemente, JC.
Consiglio F
Conte M
Conte,M.
Cooper BR
Culotti JG.
d'Adda di Fagagna F
Dang. Z.
Date, H.
DeFalco, T.
Defalco, T.
Deflorian G
Demura T
Doi K.
Doi, K.
Drapeau, P.
Dutta, NK.
Earnshaw, W.C.
Ebata, T.
Eguchi M.
Eguchi, S.
Ehlers P
Eli Kaminuma
Endo, T.
Enju, A.
Esaki, M.
Esmaeili B
Ezawa,K.
FURUYA, K.
Feldon,J.
Feng, J.
Fire AFu Y
Fujii, A.
Fujikawa, K.

C-c Division of Molecular and Developmental Biology
C-c Division of Molecular and Developmental Biology
C-c Division of Molecular and Developmental Biology
C-c Division of Molecular and Developmental Biology
L EXPERIMENTAL FARM
C-c Division of Molecular and Developmental Biology
F-b Mammalian Development Laboratory
G-c Comparative Genomics Laboratory
E-a Division of Human Genetics
E-b Division of Agricultural Genetics
I-a Laboratory for DNA Data Analysis
L EXPERIMENTAL FARM
G-b Genome biology Laboratory
G-a Genetic Informatics Laboratory
L EXPERIMENTAL FARM
G-b Genome biology Laboratory
C-c Division of Molecular and Developmental Biology
G-c Comparative Genomics Laboratory
G-c Comparative Genomics Laboratory
C-a Division of Developmental Genetics
C-a Division of Developmental Genetics
C-c Division of Molecular and Developmental Biology
L EXPERIMENTAL FARM
F-e Plant Genetics Laboratory
F-e Plant Genetics Laboratory
C-c Division of Molecular and Developmental Biology
C-c Division of Molecular and Developmental Biology
A-a Division of Molecular Genetics
G-c Comparative Genomics Laboratory
F-a Mammalian Genetics Laboratory
F-e Plant Genetics Laboratory
F-a Mammalian Genetics Laboratory
F-e Plant Genetics Laboratory
G-b Genome biology Laboratory
I-b Laboratory for Gene-Product Informatics
I-a Laboratory for DNA Data Analysis
G-c Comparative Genomics Laboratory
C-c Division of Molecular and Developmental Biology
G-b Genome biology Laboratory
D-a Division of Population Genetics
F-f Microbial Genetics Laboratory
C-b Division of Neurogenetics
A-a Division of Molecular Genetics
G-b Genome biology Laboratory
E-b Division of Agricultural Genetics
A-a Division of Molecular Genetics
D-a Division of Population Genetics

Fujisawa, H.

Gojobori,T.
Goszczynski B
Gothilf, Y.
Goto, H.
Goto, J.
Goto, M.

F-a Mammalian Genetics Laboratory
F-e Plant Genetics Laboratory
H-e Gene Network Laboratory
D-a Division of Population Genetics
F-g Invertebrate Genetics Laboratory
G-c Comparative Genomics Laboratory
F-a Mammalian Genetics Laboratory
A-a Division of Molecular Genetics
A-a Division of Molecular Genetics
A-a Division of Molecular Genetics
G-c Comparative Genomics Laboratory
C-c Division of Molecular and Developmental Biology
G-c Comparative Genomics Laboratory
I-a Laboratory for DNA Data Analysis
I-c Laboratory for Gene Function Research
L EXPERIMENTAL FARM
F-b Mammalian Development Laboratory
G-c Comparative Genomics Laboratory
G-c Comparative Genomics Laboratory
D-a Division of Population Genetics
G-b Genome biology Laboratory
C-c Division of Molecular and Developmental Biology
F-f Microbial Genetics Laboratory
F-g Invertebrate Genetics Laboratory
N Technical Section
B-a Division of Cytogenetics
G-b Genome biology Laboratory
C-c Division of Molecular and Developmental Biology
N Technical Section
I-a Laboratory for DNA Data Analysis
C-a Division of Developmental Genetics
E-c Division of Brain Function
I-a Laboratory for DNA Data Analysis
I-c Laboratory for Gene Function Research
D-a Division of Population Genetics
G-b Genome biology Laboratory
C-c Division of Molecular and Developmental Biology
G-c Comparative Genomics Laboratory
G-c Comparative Genomics Laboratory
C-c Division of Molecular and Developmental Biology

Goto, S.

F-g Invertebrate Genetics Laboratory

Gotoh, H.
Gough, C.
Grampp,T.
Gu SG
H & Namikawa
Habara, O.

F-a Mammalian Genetics Laboratory
I-a Laboratory for DNA Data Analysis
C-b Division of Neurogenetics
G-b Genome biology Laboratory
C-a Division of Developmental Genetics
F-g Invertebrate Genetics Laboratory

Fujisawa,N.
Fujita,S.
Fujitani, K.
Fujiyama, A.
Fukada, T.
Fukagawa T.
Fukagawa, T.
Fukami, K.
FukazawaH.
Fukuchi, S.
Fukuda H
Fukuda M.
Fukuda, Y.
Fukumaki, Y.
Fukumori,Y.
Fukushige T
Funahashi, J.
Furuya, K.
Galko, M. J.
Ganley, A.R.D.
Ganly, A.R.D.
Gaudet J
Gebhart, N.
Gengyo-Ando, K.
Gojobori T.
Gojobori, T.

Hakoyama T
Hamada, K.
Han, HW.
Hanada, K.
Hanaoka, F.
Hans, S.
Hansen D.
Hara, Y.
Harihara,S.
Harushima, Y.
Hasebe M
Hasebe, Y.
Hashiguchi,Y.
Hashimoto H
Hashimoto S
Hata,K.
Hatakeyama, A.
Hatori, T.
Hattori, M.
Hattori, N.
Hattori,E.
Hayakawa, Y.
Hayakawa,S.
Hayashi,H.
Hayashizaki, Y.
Henke,J.
Henke,L.
Hennig C
Hideaki Sugawara
Hidemasa Bono
Higashijima, S.
Higashijima, S.-I.
Higuchi, S.
Hirahara S.
Hirai, K.
Hirakawa J.
Hiramoto, M
Hiramoto, M.
Hirano, T.
Hiraoka, Y.
Hirasawa,R.
Hirata, T
Hirata, T.
Hirochika, H.

I-b Laboratory for Gene-Product Informatics
I-c Laboratory for Gene Function Research
C-c Division of Molecular and Developmental Biology
I-b Laboratory for Gene-Product Informatics
H-a Biological Macromolecules
C-c Division of Molecular and Developmental Biology
G-b Genome biology Laboratory
J-c Cell Architecture Laboratory
D-a Division of Population Genetics
F-a Mammalian Genetics Laboratory
F-e Plant Genetics Laboratory
L EXPERIMENTAL FARM
G-c Comparative Genomics Laboratory
D-a Division of Population Genetics
G-b Genome biology Laboratory
G-b Genome biology Laboratory
E-a Division of Human Genetics
H-b Molecular Biomechanism Laboratory
A-a Division of Molecular Genetics
G-c Comparative Genomics Laboratory
G-c Comparative Genomics Laboratory
D-a Division of Population Genetics
I-a Laboratory for DNA Data Analysis
D-a Division of Population Genetics
J-c Cell Architecture Laboratory
G-c Comparative Genomics Laboratory
D-a Division of Population Genetics
D-a Division of Population Genetics
G-b Genome biology Laboratory
I-b Laboratory for Gene-Product Informatics
I-b Laboratory for Gene-Product Informatics
C-c Division of Molecular and Developmental Biology
C-c Division of Molecular and Developmental Biology
A-a Division of Molecular Genetics
F-b Mammalian Development Laboratory
B-b Division of Microbial Genetics
F-b Mammalian Development Laboratory
C-a Division of Developmental Genetics
I-a Laboratory for DNA Data Analysis
C-a Division of Developmental Genetics
H-a Biological Macromolecules
A-a Division of Molecular Genetics
E-a Division of Human Genetics
E-c Division of Brain Function
E-c Division of Brain Function
F-e Plant Genetics Laboratory

Hirohiko Hirochika
Hiromi Y
Hiromi Y.
Hiromi, Y.
Hirose, S.
Hirst M
Hitomi Suzuki
Hitomi Suzuki.
Hitomi, J.
Hoki, Y.
Hoki,Y.
Holt RA
Homma, K.
Hong,W.
Hori H
Hori, T.
Horie, K.
Horiike T
Horiike, T.
Horikawa, D.
Horiuchi, Y.
Hoshijima, K.
Hoshino,M.
Hosoya, M.
Hrushima, Y.
Huang, C-J.
Huang, CJ.
Huang, F-L.
Hudson, D.F.
Hung, C-C.
Hung, CC.
Hwang, JS.
Hwang, SP.
Hwang, SP. L.
Iba, H.
Ibuki,IAsada
Ichiyanagi,K.
Ide, S.
Iemura, S.
Iida, K.
Iiizumi, S.
Iimura, T.
Ikawa, M.

L EXPERIMENTAL FARM
C-a Division of Developmental Genetics
C-a Division of Developmental Genetics
C-a Division of Developmental Genetics
I-a Laboratory for DNA Data Analysis
C-c Division of Molecular and Developmental Biology
G-b Genome biology Laboratory
F-b Mammalian Development Laboratory
F-b Mammalian Development Laboratory
C-c Division of Molecular and Developmental Biology
G-c Comparative Genomics Laboratory
E-a Division of Human Genetics
G-b Genome biology Laboratory
I-a Laboratory for DNA Data Analysis
I-c Laboratory for Gene Function Research
H-e Gene Network Laboratory
G-b Genome biology Laboratory
A-a Division of Molecular Genetics
G-c Comparative Genomics Laboratory
C-c Division of Molecular and Developmental Biology
G-b Genome biology Laboratory
I-c Laboratory for Gene Function Research
G-c Comparative Genomics Laboratory
F-a Mammalian Genetics Laboratory
F-e Plant Genetics Laboratory
C-c Division of Molecular and Developmental Biology
H-e Gene Network Laboratory
F-a Mammalian Genetics Laboratory
F-e Plant Genetics Laboratory
C-c Division of Molecular and Developmental Biology
C-c Division of Molecular and Developmental Biology
C-c Division of Molecular and Developmental Biology
A-a Division of Molecular Genetics
C-c Division of Molecular and Developmental Biology
C-c Division of Molecular and Developmental Biology
I-a Laboratory for DNA Data Analysis
C-c Division of Molecular and Developmental Biology
C-c Division of Molecular and Developmental Biology
A-a Division of Molecular Genetics
H-e Gene Network Laboratory
E-a Division of Human Genetics
N Technical Section
B-a Division of Cytogenetics
C-c Division of Molecular and Developmental Biology
G-c Comparative Genomics Laboratory
E-b Division of Agricultural Genetics
C-c Division of Molecular and Developmental Biology
F-d Model Fish Genomics ResourceIkeda, K.
Ikehara, T.
Ikemura, T.
Ikenaga, T.
Ikeo, K.
Ikeo, K..
Ikeo,K.
Imaizumi-Anraku H
Imamoto, N.
Imamura, S.
Imanishi, T.
Imuta Y.
Inagaki S
Inoko, H.
Inoue C
Inoue, M.
Irizawa,Y.
Ishida, J.
Ishida, Y.
Ishikawa, T.
Ishikawa,H.
Ishizaka M
Isobe, T.
Isoda, M.
Isogai, S.
Ito, A.
Ito, T.
Ito, Y.
Itoh, M.
Itoh, T.

F-c Mouse Genomics Resource Laboratory
H-a Biological Macromolecules
A-a Division of Molecular Genetics
C-c Division of Molecular and Developmental Biology
I-a Laboratory for DNA Data Analysis
I-c Laboratory for Gene Function Research
I-a Laboratory for DNA Data Analysis
D-a Division of Population Genetics
I-b Laboratory for Gene-Product Informatics
H-a Biological Macromolecules
H-a Biological Macromolecules
I-a Laboratory for DNA Data Analysis
F-b Mammalian Development Laboratory
E-b Division of Agricultural Genetics
I-a Laboratory for DNA Data Analysis
G-b Genome biology Laboratory
A-a Division of Molecular Genetics
D-a Division of Population Genetics
I-b Laboratory for Gene-Product Informatics
D-a Division of Population Genetics
H-a Biological Macromolecules
H-e Gene Network Laboratory
I-b Laboratory for Gene-Product Informatics
A-a Division of Molecular Genetics
C-c Division of Molecular and Developmental Biology
C-c Division of Molecular and Developmental Biology
C-c Division of Molecular and Developmental Biology
G-c Comparative Genomics Laboratory
F-e Plant Genetics Laboratory
C-c Division of Molecular and Developmental Biology
D-a Division of Population Genetics
G-c Comparative Genomics Laboratory
I-a Laboratory for DNA Data Analysis
B-b Division of Microbial Genetics

Itohara,S.
Itou, H.

C-b Division of Neurogenetics
H-d Biomolecular Structure Laboratory

Iwamoto, M.
Iwasato,T.
Iwata, A.
Iwata, T.
Iwayama,Y.
Izumi, Y.
Jang CW.
Jenks MA
Jiang H.
Jichun L
Jin, L.

A-a Division of Molecular Genetics
C-b Division of Neurogenetics
G-c Comparative Genomics Laboratory
F-g Invertebrate Genetics Laboratory
D-a Division of Population Genetics
I-a Laboratory for DNA Data Analysis
F-b Mammalian Development Laboratory
L EXPERIMENTAL FARM
F-e Plant Genetics Laboratory
I-b Laboratory for Gene-Product Informatics
I-a Laboratory for DNA Data Analysis

Jin,F.
Jinam,T.
Jindo T
Jones SJ
Joshi, R.
K-i.
K-i..
Kage, Y.
Kageyama, R.
Kai, C.
Kajikawa,M.
Kajino, K.
Kakimoto, T.
Kakutani T
Kalb JM.
Kamijo, R.
Kaminuma, E.
kaminuma, E.
Kanamori H.
Kanbayashi,M.
Kaneda,M.
Kanehisa, M.
kanehisa, M.
Kaneko, H.
Kania, A.
Kanie, M.
Kanie, O.
Karino, Y.
Kasahara M
Kasai, S.

D-a Division of Population Genetics
D-a Division of Population Genetics
G-b Genome biology Laboratory
G-b Genome biology Laboratory
C-a Division of Developmental Genetics
E-b Division of Agricultural Genetics
E-b Division of Agricultural Genetics
A-a Division of Molecular Genetics
G-c Comparative Genomics Laboratory
G-c Comparative Genomics Laboratory
E-a Division of Human Genetics
G-c Comparative Genomics Laboratory
A-a Division of Molecular Genetics
E-b Division of Agricultural Genetics
G-b Genome biology Laboratory
F-a Mammalian Genetics Laboratory
I-b Laboratory for Gene-Product Informatics
G-c Comparative Genomics Laboratory
F-e Plant Genetics Laboratory
E-a Division of Human Genetics
E-a Division of Human Genetics
G-c Comparative Genomics Laboratory
G-c Comparative Genomics Laboratory
C-c Division of Molecular and Developmental Biology
C-c Division of Molecular and Developmental Biology
F-g Invertebrate Genetics Laboratory
F-g Invertebrate Genetics Laboratory
F-g Invertebrate Genetics Laboratory
G-b Genome biology Laboratory
F-c Mouse Genomics Resource Laboratory

katayama, T.
Kato, H.
Kato, Y.
Katoh,H.
Katou, Y.
Katsuki T.
Katsuki, T.
Katsura, I.
Kawabata, ah.
Kawabe A
Kawaguchi M
Kawahara, A.
Kawahara, Y.
Kawai, J.

G-c Comparative Genomics Laboratory
F-a Mammalian Genetics Laboratory
F-a Mammalian Genetics Laboratory
C-b Division of Neurogenetics
B-b Division of Microbial Genetics
C-a Division of Developmental Genetics
C-a Division of Developmental Genetics
N Technical Section
G-c Comparative Genomics Laboratory
E-b Division of Agricultural Genetics
I-b Laboratory for Gene-Product Informatics
C-c Division of Molecular and Developmental Biology
I-a Laboratory for DNA Data Analysis
G-c Comparative Genomics Laboratory
I-a Laboratory for DNA Data Analysis
C-c Division of Molecular and Developmental Biology

Kawakami K

Kawakami, K.

Kimura, KD.
Kimura,N.
Kishikawa, S.
Kishimoto, Y.

C-c Division of Molecular and Developmental Biology
D-a Division of Population Genetics
F-e Plant Genetics Laboratory
G-b Genome biology Laboratory
E-c Division of Brain Function
F-d Model Fish Genomics Resource
F-b Mammalian Development Laboratory
I-b Laboratory for Gene-Product Informatics
A-a Division of Molecular Genetics
G-c Comparative Genomics Laboratory
G-c Comparative Genomics Laboratory
H-a Biological Macromolecules
L EXPERIMENTAL FARM
G-b Genome biology Laboratory
G-c Comparative Genomics Laboratory
G-c Comparative Genomics Laboratory
I-a Laboratory for DNA Data Analysis
C-c Division of Molecular and Developmental Biology
C-c Division of Molecular and Developmental Biology
J-c Cell Architecture Laboratory
F-a Mammalian Genetics Laboratory
C-c Division of Molecular and Developmental Biology
G-a Genetic Informatics Laboratory
J-c Cell Architecture Laboratory
H-a Biological Macromolecules
N Technical Section
E-a Division of Human Genetics
G-c Comparative Genomics Laboratory
C-c Division of Molecular and Developmental Biology

Kiso M.
Kitaguchi, T.
Kitano,T.
Kitayama,J.

F-b Mammalian Development Laboratory
C-c Division of Molecular and Developmental Biology
D-a Division of Population Genetics
E-a Division of Human Genetics

Kiyama, H.
Kobayashi A
Kobayashi N
Kobayashi, H.
Kobayashi, K.
Kobayashi, M.

E-c Division of Brain Function
E-b Division of Agricultural Genetics
G-b Genome biology Laboratory
I-a Laboratory for DNA Data Analysis
F-d Model Fish Genomics Resource
G-c Comparative Genomics Laboratory
C-c Division of Molecular and Developmental Biology
G-c Comparative Genomics Laboratory
B-a Division of Cytogenetics
I-a Laboratory for DNA Data Analysis
G-b Genome biology Laboratory
G-b Genome biology Laboratory
G-b Genome biology Laboratory
G-c Comparative Genomics Laboratory

Kawakita, M.
Kawano T
Kawasaki, T.
Kawashima H.
Kawashima, M.
Kawashima, T.
Kawaura, K.
Kaytayama, T.
Kazuhiro Maeshima
Ken-Ichi Nonomura
Khattra J
Kido, N.
kido, N.
Kikuchi, T.
Kikuta, H.
Kim, DJ.
Kimura, A.
Kimura, E.
Kimura, G.
Kimura, K.

Kobayashi, S.
Kobayashi, T.
Koga A
Kohara Y
Kohara Y.
Kohara, YKohara, Y.
Kohara,Y.
Koide, T.
Kojidani, T.
Kokubu, C.
Komata, M.
Komatsu,A.
Komisarczuk, A.Z.
Komiyama, T.
Komiyama. T.
Komnenovic V
Komoda, T.
Kondo, S.
Kondoh H.
Kong, X.
Konishi, H.
Kono,N.
Kosma DK
Kotani, T.
Kouchi H
Kouguchi, H.
Kousaku Okubo
Koyama, H.
Koyama,H.

G-c Comparative Genomics Laboratory
F-a Mammalian Genetics Laboratory
G-a Genetic Informatics Laboratory
C-c Division of Molecular and Developmental Biology
F-c Mouse Genomics Resource Laboratory
A-a Division of Molecular Genetics
C-c Division of Molecular and Developmental Biology
B-b Division of Microbial Genetics
H-e Gene Network Laboratory
C-c Division of Molecular and Developmental Biology
I-a Laboratory for DNA Data Analysis
I-c Laboratory for Gene Function Research
E-b Division of Agricultural Genetics
G-c Comparative Genomics Laboratory
G-c Comparative Genomics Laboratory
F-b Mammalian Development Laboratory
A-a Division of Molecular Genetics
E-c Division of Brain Function
H-e Gene Network Laboratory
L EXPERIMENTAL FARM
C-c Division of Molecular and Developmental Biology
I-b Laboratory for Gene-Product Informatics
G-c Comparative Genomics Laboratory
I-b Laboratory for Gene-Product Informatics
J-c Cell Architecture Laboratory
E-b Division of Agricultural Genetics
E-a Division of Human Genetics

Koyanagi, S.
Krause MW
Krukov,K.
Kryukov, K.

A-a Division of Molecular Genetics
G-b Genome biology Laboratory
D-a Division of Population Genetics
D-a Division of Population Genetics
I-a Laboratory for DNA Data Analysis

Kubo M
Kubo T.
Kubo T. Yamagata Y
Kubo YKubo, T.

L EXPERIMENTAL FARM
F-e Plant Genetics Laboratory
F-e Plant Genetics Laboratory
G-b Genome biology Laboratory
G-c Comparative Genomics Laboratory
F-e Plant Genetics Laboratory
G-c Comparative Genomics Laboratory
I-a Laboratory for DNA Data Analysis
G-c Comparative Genomics Laboratory
A-a Division of Molecular Genetics
G-c Comparative Genomics Laboratory
I-a Laboratory for DNA Data Analysis
I-c Laboratory for Gene Function Research
G-c Comparative Genomics Laboratory
G-c Comparative Genomics Laboratory

kubo, T.
Kubo, Y.
Kujime, Y.
Kukimoto-Niino, M.
Kuma, K.
Kumar, S.
Kunieda, T.
Kurata, N.

Machate, A.
Maeda, K.
Maeshima, K.
Makoto Kiso.

F-a Mammalian Genetics Laboratory
F-e Plant Genetics Laboratory
I-b Laboratory for Gene-Product Informatics
F-c Mouse Genomics Resource Laboratory
F-e Plant Genetics Laboratory
E-a Division of Human Genetics
G-c Comparative Genomics Laboratory
H-e Gene Network Laboratory
G-c Comparative Genomics Laboratory
G-c Comparative Genomics Laboratory
F-b Mammalian Development Laboratory
C-c Division of Molecular and Developmental Biology
L EXPERIMENTAL FARM
A-a Division of Molecular Genetics
C-c Division of Molecular and Developmental Biology
G-b Genome biology Laboratory
C-c Division of Molecular and Developmental Biology
C-c Division of Molecular and Developmental Biology
E-a Division of Human Genetics
B-b Division of Microbial Genetics
C-c Division of Molecular and Developmental Biology
C-c Division of Molecular and Developmental Biology
F-c Mouse Genomics Resource Laboratory
A-a Division of Molecular Genetics
C-a Division of Developmental Genetics
I-a Laboratory for DNA Data Analysis
C-c Division of Molecular and Developmental Biology
F-g Invertebrate Genetics Laboratory
H-a Biological Macromolecules
F-b Mammalian Development Laboratory

Mang HG
Mano, S.
Marin, W.
Maro, G.
Maro, G.S.
Marra MA
Maruyama,Y.
Masuda, A.
Masuzaki, S.
Mathieu O
Matsubara J
Matsuda S.
Matsui, A.
Matsumoto T
Matsumoto T.
Matsumoto, J.
Matsumoto, K.

L EXPERIMENTAL FARM
I-a Laboratory for DNA Data Analysis
C-c Division of Molecular and Developmental Biology
C-c Division of Molecular and Developmental Biology
C-c Division of Molecular and Developmental Biology
G-b Genome biology Laboratory
H-e Gene Network Laboratory
F-d Model Fish Genomics Resource
G-c Comparative Genomics Laboratory
E-b Division of Agricultural Genetics
I-b Laboratory for Gene-Product Informatics
F-b Mammalian Development Laboratory
I-b Laboratory for Gene-Product Informatics
I-b Laboratory for Gene-Product Informatics
F-e Plant Genetics Laboratory
G-c Comparative Genomics Laboratory
C-c Division of Molecular and Developmental Biology

Kurihara, Y.
Kuriki, S.
Kurimoto,K.
Kuroki, Y.
Kurusu,M.
Kuwahara, H.
Kuwahara, h.
Kylie Lopes Floro
Lal, P.
Laluk KA
Lampson, M.A.
Lanfrancone L
Langenhan T
Lee, HK.
Lee, HY.
Lee,J.
Li, Y.
Liao, M.
Lieschke, G.J.
Lionikas, A.
Liu, D.
Liu, QX.

Matsumoto, R.
Matsunaga, N.
Matsunami M.
Matsuoka, S.
Matsushima K
Matsushima, A.
Matsuya, A.
McCouch S.
McGhee JD
Mekada, K.
Mello CC
Mengiste T
Merz DC
Mestek L
Mignot, E.
Mineta, K.
Minezaki, Y.
Minnema SE
Minoshima ,Y.
Mita, A.
Mitani, K.
Mitani, S.
Mitsugu Eiguchi
Mitsui, K.
Mitsui,J.
Mitsuyama, T.
Miura A
Miura, M.

I-a Laboratory for DNA Data Analysis
A-a Division of Molecular Genetics
D-a Division of Population Genetics
C-a Division of Developmental Genetics
G-b Genome biology Laboratory
I-b Laboratory for Gene-Product Informatics
I-a Laboratory for DNA Data Analysis
F-e Plant Genetics Laboratory
G-b Genome biology Laboratory
F-a Mammalian Genetics Laboratory
G-b Genome biology Laboratory
L EXPERIMENTAL FARM
G-b Genome biology Laboratory
G-b Genome biology Laboratory
C-c Division of Molecular and Developmental Biology
I-a Laboratory for DNA Data Analysis
I-a Laboratory for DNA Data Analysis
G-b Genome biology Laboratory
A-a Division of Molecular Genetics
F-a Mammalian Genetics Laboratory
F-d Model Fish Genomics Resource
N Technical Section
L EXPERIMENTAL FARM
F-d Model Fish Genomics Resource
G-c Comparative Genomics Laboratory
G-c Comparative Genomics Laboratory
E-b Division of Agricultural Genetics
C-c Division of Molecular and Developmental Biology

Miyamoto R
Miyamoto T
Miyanari,Y.
Miyao, A.
Miyasaka, N.
Miyashita, N.
Miyata, D.
Miyawaki, A.
Miyazaki S
Miyazaki, Y.
Miyoshi,H.
Mizoguchi, T.
Mizushina, Y.

G-b Genome biology Laboratory
G-b Genome biology Laboratory
E-a Division of Human Genetics
F-e Plant Genetics Laboratory
C-c Division of Molecular and Developmental Biology
F-a Mammalian Genetics Laboratory
I-c Laboratory for Gene Function Research
C-c Division of Molecular and Developmental Biology
L EXPERIMENTAL FARM
F-e Plant Genetics Laboratory
E-a Division of Human Genetics
C-c Division of Molecular and Developmental Biology
D-a Division of Population Genetics
F-a Mammalian Genetics Laboratory
G-c Comparative Genomics Laboratory
F-e Plant Genetics Laboratory
G-c Comparative Genomics Laboratory
E-b Division of Agricultural Genetics
G-b Genome biology Laboratory

Mizuta, I.
Mizuta, Y.
Mochida, K.
Mochiduki, T.
Mochizuki T

Mochizuki, T.

Mochizuki, Y.
Moerman DG
Mohler,H.
Mohri-Shiomi, A.
Mori, H.
Mori, R.
Mori,C.
Morimoto, K.
Morishita S.
Morita, R.
Moriwaki, K.
Morosawa, T.
Mosiolek M
Motoyama, A.
Mourrain, P.
Munakata, K.
Murakami S.
Murakami, K.
Muramatsu, S.
Murata T
Murata, M.
Murata, T.
Murayama, A.

G-c Comparative Genomics Laboratory
F-a Mammalian Genetics Laboratory
F-e Plant Genetics Laboratory
I-b Laboratory for Gene-Product Informatics
G-b Genome biology Laboratory
C-b Division of Neurogenetics
N Technical Section
F-f Microbial Genetics Laboratory
C-c Division of Molecular and Developmental Biology
A-a Division of Molecular Genetics
C-c Division of Molecular and Developmental Biology
G-b Genome biology Laboratory
C-c Division of Molecular and Developmental Biology
F-a Mammalian Genetics Laboratory
I-b Laboratory for Gene-Product Informatics
E-b Division of Agricultural Genetics
G-c Comparative Genomics Laboratory
C-c Division of Molecular and Developmental Biology
C-c Division of Molecular and Developmental Biology
H-d Biomolecular Structure Laboratory
I-a Laboratory for DNA Data Analysis
B-b Division of Microbial Genetics
L EXPERIMENTAL FARM
G-c Comparative Genomics Laboratory
G-c Comparative Genomics Laboratory
H-a Biological Macromolecules

Muto, A.
Na, YR.
Nagata, T.
Nakadate, Y.
Nakade, K.
Nakagawa, S.
Nakajima,M.
Nakamura M
Nakamura Y
Nakamura, A.
Nakamura, H.
Nakamura, M.
Nakamura, N.
Nakamura, Y.
Nakao, R.
Nakatani Y
Nakatsuji, N.
Nakatsuji,N.
Nakayama, R.
Nakayama, T.
Nakayama,M.

C-c Division of Molecular and Developmental Biology
C-c Division of Molecular and Developmental Biology
G-c Comparative Genomics Laboratory
E-c Division of Brain Function
G-c Comparative Genomics Laboratory
I-a Laboratory for DNA Data Analysis
D-a Division of Population Genetics
E-b Division of Agricultural Genetics
I-b Laboratory for Gene-Product Informatics
F-g Invertebrate Genetics Laboratory
C-c Division of Molecular and Developmental Biology
F-a Mammalian Genetics Laboratory
C-c Division of Molecular and Developmental Biology
G-c Comparative Genomics Laboratory
G-c Comparative Genomics Laboratory
G-b Genome biology Laboratory
G-c Comparative Genomics Laboratory
E-a Division of Human Genetics
C-c Division of Molecular and Developmental Biology
E-b Division of Agricultural Genetics
H-e Gene Network Laboratory

Nakayana,M.
Nakayashiki,N.
Namikawa, H. &Narita T
Naruse K
Natsume, T.
Negishi,M.
Niimi K
Niki, H.
Nishi, A.
Nishida, Y.
Nishida,M.
Nishihara, S.
Nishijima, H.
Nishikawa, K.

H-e Gene Network Laboratory
D-a Division of Population Genetics
C-a Division of Developmental Genetics
G-b Genome biology Laboratory
G-b Genome biology Laboratory
C-c Division of Molecular and Developmental Biology
C-b Division of Neurogenetics
I-b Laboratory for Gene-Product Informatics
F-f Microbial Genetics Laboratory
F-c Mouse Genomics Resource Laboratory
G-c Comparative Genomics Laboratory
D-a Division of Population Genetics
F-g Invertebrate Genetics Laboratory
E-b Division of Agricultural Genetics
C-c Division of Molecular and Developmental Biology
I-a Laboratory for DNA Data Analysis
I-c Laboratory for Gene Function Research

Nishikawa, K..
Nishimukai,H.
Nishimura, A.
Nishimura, K.
Nishino, Y.
Nishinoue, K.
Nishiwaki K

I-a Laboratory for DNA Data Analysis
D-a Division of Population Genetics
D-a Division of Population Genetics
A-a Division of Molecular Genetics
H-a Biological Macromolecules
F-g Invertebrate Genetics Laboratory
G-b Genome biology Laboratory

Niwayama, R.
Nobuo Sasaki.
Noda,R.
Nogata K
Noguchi, H.
Nohno, T.
Nomura M
Nomura, Y.
Nonomura, K.
Nori Kurata
Noro, C.
Nosaka, T.
Oates, A.C.
Obata, Y.

J-c Cell Architecture Laboratory
F-b Mammalian Development Laboratory
D-a Division of Population Genetics
G-b Genome biology Laboratory
G-c Comparative Genomics Laboratory
F-a Mammalian Genetics Laboratory
I-b Laboratory for Gene-Product Informatics
A-a Division of Molecular Genetics
C-c Division of Molecular and Developmental Biology
L EXPERIMENTAL FARM
F-a Mammalian Genetics Laboratory
A-a Division of Molecular Genetics
C-c Division of Molecular and Developmental Biology
G-c Comparative Genomics Laboratory
F-a Mammalian Genetics Laboratory
I-e Laboratory for Gene-Expression Analysis
G-b Genome biology Laboratory
A-a Division of Molecular Genetics
F-b Mammalian Development Laboratory
E-b Division of Agricultural Genetics
E-a Division of Human Genetics
G-b Genome biology Laboratory

Ogasawara O.
Ogawa M
Ogawa, H.
Oginuma M.
Ogura, S-i.
Ohhata,T.
Ohishi K

Ohmi, S.
Ohyama M.
Ohyanagi, H.
Oishi, A.
Oka, A.
Okabe, A.
Okabe,M.
Okada N.
Okada, M.
Okada, S.
Okamoto, H.
Okano H.
Okano HJ.
Okano,M.

G-c Comparative Genomics Laboratory
F-b Mammalian Development Laboratory
G-c Comparative Genomics Laboratory
N Technical Section
F-a Mammalian Genetics Laboratory
I-a Laboratory for DNA Data Analysis
F-g Invertebrate Genetics Laboratory
H-e Gene Network Laboratory
G-b Genome biology Laboratory
A-a Division of Molecular Genetics
G-c Comparative Genomics Laboratory
C-c Division of Molecular and Developmental Biology
F-b Mammalian Development Laboratory
F-b Mammalian Development Laboratory
E-a Division of Human Genetics

Okawa, K.
Okazawa,H.
Oku, Y.
Okubo K.
Okuda,T.
Onishi, K.
Ono, F.
Ono, T.
Ookata, K.
Oota, S.
Oshima N.
Ozaki, M.
Ozaki, Y.
Ozato K
Ozawa, A.
Padhukasahasram B.
Park HC
Park, JH.
Park, SH.
Parsons EP
Pezzimenti F
Phipps,M.
Picker, A.
Potter,C.
Prenosil,G.
Promel S
Rie Saba
Rie Saba.
Ruchaud, S.
Ruddle, FH.
Russ AP.

A-a Division of Molecular Genetics
H-e Gene Network Laboratory
G-c Comparative Genomics Laboratory
I-e Laboratory for Gene-Expression Analysis
H-e Gene Network Laboratory
G-c Comparative Genomics Laboratory
C-c Division of Molecular and Developmental Biology
E-b Division of Agricultural Genetics
C-c Division of Molecular and Developmental Biology
F-a Mammalian Genetics Laboratory
F-b Mammalian Development Laboratory
D-a Division of Population Genetics
F-d Model Fish Genomics Resource
G-b Genome biology Laboratory
I-a Laboratory for DNA Data Analysis
F-e Plant Genetics Laboratory
L EXPERIMENTAL FARM
C-c Division of Molecular and Developmental Biology
C-c Division of Molecular and Developmental Biology
L EXPERIMENTAL FARM
C-c Division of Molecular and Developmental Biology
D-a Division of Population Genetics
C-c Division of Molecular and Developmental Biology
H-e Gene Network Laboratory
C-b Division of Neurogenetics
G-b Genome biology Laboratory
F-b Mammalian Development Laboratory
F-b Mammalian Development Laboratory
A-a Division of Molecular Genetics
D-a Division of Population Genetics
G-b Genome biology Laboratory

Ruzanov P
Saba R.
Sada A.
Sado, T.
Sado, Y.
Sado,T.
Saga Y
Saga Y.
Sagai, T.
Saigo, K.
Saito T
Saito, K.
Saitoh, K.
Saitou N.
Saitou, N.
Saitou,M.
Saitou,N.
Saka, K.
Sakaguchi, T.

Sakahara, M.
Sakai, N.
Sakaki, Y.
Sakamoto, S.
Sakaniwa, S.
Sakate, R.
Sakaue-Sawano, A.
Sakurai, M.
Sakurai-Ozato N
Sanbonmatsu, R.
Santoriello C
Sarai,Y.
Saruhashi, S.
Sasaki A
Sasaki S
Sasaki, H.
Sasaki,H.
Satake, T.
Sato K
Sato S
Sato, K.
Sato, T.

G-b Genome biology Laboratory
F-b Mammalian Development Laboratory
F-b Mammalian Development Laboratory
G-c Comparative Genomics Laboratory
F-d Model Fish Genomics Resource
E-a Division of Human Genetics
F-b Mammalian Development Laboratory
F-b Mammalian Development Laboratory
D-a Division of Population Genetics
F-a Mammalian Genetics Laboratory
F-g Invertebrate Genetics Laboratory
G-b Genome biology Laboratory
F-d Model Fish Genomics Resource
B-b Division of Microbial Genetics
D-a Division of Population Genetics
D-a Division of Population Genetics
E-a Division of Human Genetics
D-a Division of Population Genetics
N Technical Section
B-a Division of Cytogenetics
E-b Division of Agricultural Genetics
F-a Mammalian Genetics Laboratory
F-c Mouse Genomics Resource Laboratory
F-e Plant Genetics Laboratory
F-a Mammalian Genetics Laboratory
F-d Model Fish Genomics Resource
G-c Comparative Genomics Laboratory
I-a Laboratory for DNA Data Analysis
I-c Laboratory for Gene Function Research
G-a Genetic Informatics Laboratory
I-a Laboratory for DNA Data Analysis
C-c Division of Molecular and Developmental Biology
G-c Comparative Genomics Laboratory
L EXPERIMENTAL FARM
I-a Laboratory for DNA Data Analysis
C-c Division of Molecular and Developmental Biology
D-a Division of Population Genetics
I-c Laboratory for Gene Function Research
G-b Genome biology Laboratory
G-b Genome biology Laboratory
G-c Comparative Genomics Laboratory
E-a Division of Human Genetics
G-c Comparative Genomics Laboratory
G-b Genome biology Laboratory
I-b Laboratory for Gene-Product Informatics
G-a Genetic Informatics Laboratory
A-a Division of Molecular Genetics

Sato, Y.
Sato,Y.
Satoshi Saruhashi
Saze H
Schnabel R
Schoft V
Seino, H.
Seki M
Seki, M.
Seki,M.

I-a Laboratory for DNA Data Analysis
D-a Division of Population Genetics
I-b Laboratory for Gene-Product Informatics
E-b Division of Agricultural Genetics
G-b Genome biology Laboratory
E-b Division of Agricultural Genetics
A-c Molecular Mechanism Laboratory
G-b Genome biology Laboratory
G-c Comparative Genomics Laboratory
I-b Laboratory for Gene-Product Informatics
G-a Genetic Informatics Laboratory

Seok SH.
Seok, SH.
Sera, M.
Setoguchi, Y.
Shang, W.
Sharma,A.
Shiba D
Shibahara, K-i.
Shibahara, S.

C-c Division of Molecular and Developmental Biology
C-c Division of Molecular and Developmental Biology
I-a Laboratory for DNA Data Analysis
F-g Invertebrate Genetics Laboratory
G-c Comparative Genomics Laboratory
E-b Division of Agricultural Genetics
G-b Genome biology Laboratory
E-b Division of Agricultural Genetics
I-a Laboratory for DNA Data Analysis

Shibahara,K.
Shibata, H.
Shibata, T.
Shidahara, Y.
Shigeta M.
Shigeyoshi, Y.
Shikata, K.
Shimada A
Shimada, MK.
Shimada,M.K.
Shimizu
Shimizu A.
Shimizu N
Shimizu, H.
Shimizu,H.
Shin-I T
Shin-I, T.
Shin-I, t.
Shin-i, T.
Shin-i,T.
Shinichiro Yamaki
Shinozaki K
Shinozaki, K.

E-b Division of Agricultural Genetics
G-c Comparative Genomics Laboratory
G-c Comparative Genomics Laboratory
G-a Genetic Informatics Laboratory
F-b Mammalian Development Laboratory
C-c Division of Molecular and Developmental Biology
E-c Division of Brain Function
G-b Genome biology Laboratory
I-a Laboratory for DNA Data Analysis
D-a Division of Population Genetics
C-a Division of Developmental Genetics
F-b Mammalian Development Laboratory
G-b Genome biology Laboratory
C-a Division of Developmental Genetics
C-a Division of Developmental Genetics
G-b Genome biology Laboratory
G-c Comparative Genomics Laboratory
G-c Comparative Genomics Laboratory
F-a Mammalian Genetics Laboratory
G-a Genetic Informatics Laboratory
L EXPERIMENTAL FARM
G-b Genome biology Laboratory
G-c Comparative Genomics Laboratory
I-b Laboratory for Gene-Product Informatics
G-a Genetic Informatics Laboratory
I-c Laboratory for Gene Function Research

Shinozaki,K.
Shinozawa, T.

Shinya, M.
Shiomi, D.
Shirahige, K.
Shiraki, T.
Shirakihara, Y.
Shiroishi T.
Shiroishi, T.

F-d Model Fish Genomics Resource
F-f Microbial Genetics Laboratory
B-b Division of Microbial Genetics
C-c Division of Molecular and Developmental Biology
H-d Biomolecular Structure Laboratory
F-b Mammalian Development Laboratory
F-a Mammalian Genetics Laboratory
F-c Mouse Genomics Resource Laboratory
F-e Plant Genetics Laboratory
I-a Laboratory for DNA Data Analysis

Shirouzu, M.
Shiwaku,H.
Siegfrid, K.R.
Singer,P.
Slusarz L
Smith, S.J.
Sone,M.
Sonoda, E.
Stanley-Troy Artap

A-a Division of Molecular Genetics
H-e Gene Network Laboratory
F-d Model Fish Genomics Resource
C-b Division of Neurogenetics
E-b Division of Agricultural Genetics
C-c Division of Molecular and Developmental Biology
H-e Gene Network Laboratory
A-a Division of Molecular Genetics
F-b Mammalian Development Laboratory

Suetake,I.
Sugano S
Sugano, S.
Suganuma N.
Sugawara, H.

E-a Division of Human Genetics
G-b Genome biology Laboratory
G-c Comparative Genomics Laboratory
I-b Laboratory for Gene-Product Informatics
G-a Genetic Informatics Laboratory
I-a Laboratory for DNA Data Analysis
I-c Laboratory for Gene Function Research
G-c Comparative Genomics Laboratory
F-c Mouse Genomics Resource Laboratory
C-c Division of Molecular and Developmental Biology
D-a Division of Population Genetics
D-a Division of Population Genetics
C-c Division of Molecular and Developmental Biology
D-a Division of Population Genetics
F-a Mammalian Genetics Laboratory
C-c Division of Molecular and Developmental Biology
C-c Division of Molecular and Developmental Biology
D-a Division of Population Genetics
F-b Mammalian Development Laboratory
F-a Mammalian Genetics Laboratory
F-b Mammalian Development Laboratory
H-d Biomolecular Structure Laboratory
G-b Genome biology Laboratory
A-a Division of Molecular Genetics
I-a Laboratory for DNA Data Analysis
E-c Division of Brain Function
G-c Comparative Genomics Laboratory
I-a Laboratory for DNA Data Analysis

Sugimoto, C.
Sugimoto, H.
Sugiyama, M.
Sugiyama,Y.
Sumiyama K.
Sumiyama, K.

Suster, M.L.
Suster, ML.
Suzuki A.
Suzuki D.
Suzuki H.
Suzuki T.
Suzuki Y
Suzuki, A.
Suzuki, H.
Suzuki, I.
Suzuki, T.
Suzuki, Y.

Suzuki,ESuzuki,E.
Suzuki,J.
Suzuki. Y.
Sweeney M.
Tabata R
Tabata S
Tachibana, M.
Tajima S
Tajima,S.
Takada, T.
Takahashi, A.
Takahashi, K.
Takahashi, K.R.
Takahashi, M.
Takahashi, N.
Takahashi, Y.

Takahashi,M.
Takahoko, M.
Takako Mochizuki
Takakubo, H.
Takami, Y.
Takano-Kai N.
Takano-Shimizu, T
Takano-Shimizu, T.
Takano-Shimizu,T.
Takano-shimizu, T.
Takashi Gojobori
Takashima,S.
Takata, H.
Takata,H.
Takeda H
Takeda K
Takeda, J.
Takeda, S.

Takeda,K.
Takeda,S.
Takehashi,M.
Takehide Kosuge
Takemoto, A.
Takemura, M.

H-e Gene Network Laboratory
H-e Gene Network Laboratory
E-a Division of Human Genetics
G-c Comparative Genomics Laboratory
F-e Plant Genetics Laboratory
I-b Laboratory for Gene-Product Informatics
I-b Laboratory for Gene-Product Informatics
I-a Laboratory for DNA Data Analysis
I-b Laboratory for Gene-Product Informatics
E-a Division of Human Genetics
F-a Mammalian Genetics Laboratory
F-e Plant Genetics Laboratory
D-a Division of Population Genetics
F-c Mouse Genomics Resource Laboratory
F-g Invertebrate Genetics Laboratory
D-a Division of Population Genetics
D-a Division of Population Genetics
A-a Division of Molecular Genetics
G-c Comparative Genomics Laboratory
H-a Biological Macromolecules
C-c Division of Molecular and Developmental Biology
D-a Division of Population Genetics
C-c Division of Molecular and Developmental Biology
I-b Laboratory for Gene-Product Informatics
C-c Division of Molecular and Developmental Biology
E-b Division of Agricultural Genetics
F-e Plant Genetics Laboratory
D-a Division of Population Genetics
D-a Division of Population Genetics
D-a Division of Population Genetics
D-a Division of Population Genetics
I-a Laboratory for DNA Data Analysis
E-a Division of Human Genetics
E-b Division of Agricultural Genetics
E-b Division of Agricultural Genetics
G-b Genome biology Laboratory
G-b Genome biology Laboratory
C-c Division of Molecular and Developmental Biology
A-a Division of Molecular Genetics
F-a Mammalian Genetics Laboratory
F-d Model Fish Genomics Resource
G-a Genetic Informatics Laboratory
E-a Division of Human Genetics
E-a Division of Human Genetics
I-b Laboratory for Gene-Product Informatics
H-a Biological Macromolecules
F-g Invertebrate Genetics Laboratory

Takenaka,O.
Takeshi Konno
Takeshima,S.
Takeuchi, M.
Takeuchi,S.
Takisawa, H.
Tamai KK
Tamaru H
Tamura, K.
Tamura, M.
Tamura,T.
Tanabe, H.
Tanaiguchi, Y.
Tanaka S.
Tanaka T.
Tanaka, H.
Tanaka, I.
Tanaka, K.
Tanaka, K.M.
Tanaka, M.
Tanaka, S.
Tanaka, T.
Tanaka,S.
Tanaka,Y.
Taniguchi, T.
Tanikawa, H.
Tanino, S.
Tateno, Y.
Tatsumi K
Tatsuta, T.
Taya, C.
Terajima, .
To, H.
Tobisawa Y.
Toda, T.
Tokumoto, M.
Toshihisa Takagi
Totoki, Y.
Tovin, A.
Toyoda, A.
Toyoda, T.
Toyokuni,S.

D-a Division of Population Genetics
I-b Laboratory for Gene-Product Informatics
D-a Division of Population Genetics
C-c Division of Molecular and Developmental Biology
C-b Division of Neurogenetics
A-a Division of Molecular Genetics
G-b Genome biology Laboratory
E-b Division of Agricultural Genetics
C-c Division of Molecular and Developmental Biology
D-a Division of Population Genetics
F-a Mammalian Genetics Laboratory
H-e Gene Network Laboratory
F-a Mammalian Genetics Laboratory
F-d Model Fish Genomics Resource
F-b Mammalian Development Laboratory
F-b Mammalian Development Laboratory
B-b Division of Microbial Genetics
H-d Biomolecular Structure Laboratory
G-c Comparative Genomics Laboratory
D-a Division of Population Genetics
I-b Laboratory for Gene-Product Informatics
C-c Division of Molecular and Developmental Biology
F-a Mammalian Genetics Laboratory
B-b Division of Microbial Genetics
F-g Invertebrate Genetics Laboratory
B-b Division of Microbial Genetics
B-b Division of Microbial Genetics
E-a Division of Human Genetics
G-c Comparative Genomics Laboratory
H-d Biomolecular Structure Laboratory
C-c Division of Molecular and Developmental Biology
I-a Laboratory for DNA Data Analysis
I-c Laboratory for Gene Function ResearchI-b Laboratory for Gene-Product Informatics
D-a Division of Population Genetics
I-a Laboratory for DNA Data Analysis
G-c Comparative Genomics Laboratory
A-a Division of Molecular Genetics
F-b Mammalian Development Laboratory
G-c Comparative Genomics Laboratory
F-d Model Fish Genomics Resource
I-b Laboratory for Gene-Product Informatics
G-c Comparative Genomics Laboratory
C-c Division of Molecular and Developmental Biology
G-c Comparative Genomics Laboratory
F-a Mammalian Genetics Laboratory
I-b Laboratory for Gene-Product Informatics
E-a Division of Human Genetics

Toyota,T.
Tsuchiya, K.

D-a Division of Population Genetics
F-a Mammalian Genetics Laboratory

Tsuchiya, R.
Tsuda, K.
Tsuji, S.
Tsukahara S
Tsumaki, N.
Twell D
Uchida, A.
Uchida, K.
Uchida,A.
Uchiyama, Y.
Ueda, H.

G-a Genetic Informatics Laboratory
F-e Plant Genetics Laboratory
G-c Comparative Genomics Laboratory
E-b Division of Agricultural Genetics
F-a Mammalian Genetics Laboratory
E-b Division of Agricultural Genetics
A-a Division of Molecular Genetics
E-c Division of Brain Function
H-e Gene Network Laboratory
C-c Division of Molecular and Developmental Biology
G-c Comparative Genomics Laboratory
C-a Division of Developmental Genetics
I-a Laboratory for DNA Data Analysis

Ueda, R.
Uehara, S.
Ukita K.
Umeda,M.
Umemori, J.
Umemori, M.
Umetsu,K.
Uno, T.
Urasaki, A.
Urban, J.
Vagnarelli, P.
Vakonakis I
Valiente, G.
Vleugel, M.
Wada, N.
Wakaguri, H.
Wakamatsu Y.
Waller-Evans H
Wang X
Wang, CC.
Wang, G.
Wang, G.X.
Wang, W.
Wang, Y.
Warner A
Watanabe H
Watanabe M
Watanabe N
Watanabe, J.
Watanabe, K.
Watanabe, N.

F-g Invertebrate Genetics Laboratory
I-a Laboratory for DNA Data Analysis
F-b Mammalian Development Laboratory
H-e Gene Network Laboratory
F-c Mouse Genomics Resource Laboratory
F-g Invertebrate Genetics Laboratory
D-a Division of Population Genetics
F-c Mouse Genomics Resource Laboratory
C-c Division of Molecular and Developmental Biology
C-c Division of Molecular and Developmental Biology
A-a Division of Molecular Genetics
G-b Genome biology Laboratory
I-a Laboratory for DNA Data Analysis
A-a Division of Molecular Genetics
F-a Mammalian Genetics Laboratory
G-c Comparative Genomics Laboratory
G-b Genome biology Laboratory
G-b Genome biology Laboratory
G-b Genome biology Laboratory
I-a Laboratory for DNA Data Analysis
C-c Division of Molecular and Developmental Biology
C-c Division of Molecular and Developmental Biology
C-c Division of Molecular and Developmental Biology
F-g Invertebrate Genetics Laboratory
G-b Genome biology Laboratory
I-b Laboratory for Gene-Product Informatics
G-b Genome biology Laboratory
G-b Genome biology Laboratory
G-c Comparative Genomics Laboratory
G-c Comparative Genomics Laboratory
H-d Biomolecular Structure Laboratory

Watanabe, T.
Watanabe, Y.
Weinberg, ES.
Wilson, S.
Wilson, SW.
Win, KT.
Wong KWu, BK.
Wu, Y.
Xu, Z.
Yabuta,Y.
Yagi, K.
Yagita, K.

G-c Comparative Genomics Laboratory
H-a Biological Macromolecules
C-c Division of Molecular and Developmental Biology
C-c Division of Molecular and Developmental Biology
C-c Division of Molecular and Developmental Biology
F-e Plant Genetics Laboratory
G-b Genome biology Laboratory
C-c Division of Molecular and Developmental Biology
F-g Invertebrate Genetics Laboratory
A-a Division of Molecular Genetics
E-a Division of Human Genetics
G-c Comparative Genomics Laboratory
C-c Division of Molecular and Developmental Biology

Yagura, M.
Yamada A.
Yamada,K.
Yamagata, Y.
Yamaguchi, A.
Yamaguchi, K.
Yamaguchi, Y.
Yamaguchi,K.
Yamaguchi,S.
Yamaji M.
Yamakawa, T.
Yamaki, S.
Yamaki,N.
Yamamoto, H.
Yamamoto, M.

B-b Division of Microbial Genetics
F-a Mammalian Genetics Laboratory
D-a Division of Population Genetics
F-e Plant Genetics Laboratory
G-c Comparative Genomics Laboratory
H-a Biological Macromolecules
C-c Division of Molecular and Developmental Biology
E-a Division of Human Genetics
E-a Division of Human Genetics
F-b Mammalian Development Laboratory
G-a Genetic Informatics Laboratory
F-e Plant Genetics Laboratory
C-b Division of Neurogenetics
I-a Laboratory for DNA Data Analysis
G-c Comparative Genomics Laboratory
C-c Division of Molecular and Developmental Biology
G-c Comparative Genomics Laboratory
F-g Invertebrate Genetics Laboratory
G-c Comparative Genomics Laboratory
I-a Laboratory for DNA Data Analysis
G-c Comparative Genomics Laboratory
F-d Model Fish Genomics Resource
G-c Comparative Genomics Laboratory
G-b Genome biology Laboratory
G-a Genetic Informatics Laboratory
G-a Genetic Informatics Laboratory
H-a Biological Macromolecules
C-c Division of Molecular and Developmental Biology
I-b Laboratory for Gene-Product Informatics
G-c Comparative Genomics Laboratory
C-c Division of Molecular and Developmental Biology

Yamamoto, Y.
Yamamoto-Hino, M.
Yamano, T.
Yamasaki, C.
Yamasaki, T.
Yamashita, M.
Yamato, K.
Yamazaki Y
Yamazaki, Y.
Yamazaki,Y.
Yanagisawa, J.
Yang, CH.
Yano K
Yano, T.
Yao, M.
Yasuhara R.

H-d Biomolecular Structure Laboratory
F-a Mammalian Genetics Laboratory

Yasui, H.
Yasukazu Nakamura
Yasumasa Shigemoto
Yasunaga,K.
Yayoi Ueda
Yee,B.K.
Yen, T.J.
Yokogawa, T.
Yokoyama T
Yokoyama, H.
Yokoyama, S.

F-e Plant Genetics Laboratory
I-b Laboratory for Gene-Product Informatics
I-b Laboratory for Gene-Product Informatics
H-e Gene Network Laboratory
L EXPERIMENTAL FARM
C-b Division of Neurogenetics
A-a Division of Molecular Genetics
C-c Division of Molecular and Developmental Biology
G-b Genome biology Laboratory
C-c Division of Molecular and Developmental Biology
A-a Division of Molecular Genetics
H-a Biological Macromolecules

Yonekawa, H.
Yonemura, S.
Yoshida H
Yoshida M.
Yoshida S.
Yoshida, A.
Yoshida, J.
Yoshida,H.
Yoshihara, Y.
Yoshikawa,T.
Yoshikazu Kuwana
Yoshiki A.
Yoshiki, A.
Yoshimoto A.
Yoshimune,K.
Yoshimura A.
Yoshimura, A.
Yoshimura, S.
Yuasa, S.
Yuasa,I.
Yuichi Kodama
Yukiko Yamazaki
Yumiko Saga
Yusuke Okubo
Zapf R
Zhang, H.
Zhao Y
Zheng H
Zhu,H.

F-a Mammalian Genetics Laboratory
I-a Laboratory for DNA Data Analysis
C-c Division of Molecular and Developmental Biology
G-b Genome biology Laboratory
H-d Biomolecular Structure Laboratory
F-b Mammalian Development Laboratory
C-c Division of Molecular and Developmental Biology
C-c Division of Molecular and Developmental Biology
G-a Genetic Informatics Laboratory
C-c Division of Molecular and Developmental Biology
D-a Division of Population Genetics
I-b Laboratory for Gene-Product Informatics
G-c Comparative Genomics Laboratory
F-a Mammalian Genetics Laboratory
F-b Mammalian Development Laboratory
H-d Biomolecular Structure Laboratory
F-e Plant Genetics Laboratory
F-e Plant Genetics Laboratory
E-c Division of Brain Function
F-c Mouse Genomics Resource Laboratory
D-a Division of Population Genetics
I-b Laboratory for Gene-Product Informatics
G-a Genetic Informatics Laboratory
F-b Mammalian Development Laboratory
F-b Mammalian Development Laboratory
G-b Genome biology Laboratory
I-a Laboratory for DNA Data Analysis
G-b Genome biology Laboratory
G-b Genome biology Laboratory
H-e Gene Network Laboratory

Zinn,K.

H-e Gene Network LaboratorybackAnnual Report 2009

No. 60back

Biological Symposium
Apr, 3 次世代バイオイメージング法の目指すところ～高エネルギー１分子計測の役割～
2009 （佐々木裕二）
Apr,
16
2009

ショウジョウバエの始原生殖細胞発生におけるシグナル伝達と生殖幹細胞のニッチ形成機構（佐藤卓也）

Apr,
17
2009

Notch signaling is essential for coordinating cell fate, morphogenesis and migrationin the lateral line primordium (Miho Matsuda)

Apr,
24
2009

Evolution of placenta: maternal-fetal communication,attachement/invasion andplacental formation (Kazuhiko Imagawa)

May,
20
2009

Organization, development and function of glial cells in the Drosophila brain(Takeshi
Awasaki)

May,
20
2009

タンパク質相互作用ネットワークの大規模解析（夏目徹）

May,
26
2009

Activity-dependent Development of Interhemispheric Connections in Mouse
Cerebral Cortex (Hidenobu Mizuno)

May,
26
2009

Lineage specific diversification of duplicated gene function in teleost fish(Hayato
Yokoi)

May,
26
2009

S100B protein secreted from glial cells in the brain modulates neural network
activity (Seiichi Sakatani)

May,
28
2009

形態の人類学―骨と歯から―（石田肇）

Jun, 3 The DNA-binding proteins are required for the establishment of centromere
2009 chromatin (Tetsuya Hori)(堀哲也)
Jun, 5 Structural kinetics of promoter binding and melting by E. coil RNA polymerase
2009 (Bianca Sclavi)Jun, 8 DNA methylation and transgenerational epigenetic inheritance in plants (Jerzy2009 Paszkowski)
Jun,
11
2009

Genetic Mosaic Analysis of Drosophila Brain Development (Tzumin Lee)

Jun,
11
2009

Growing around the clock: internal clocks regulate growth vigor in hybrids andallotetraploids (Jeffrey Chen)

Jun,
22
2009

Distinct roles of the FGF system in the development of excitatory and inhibitory
neurons in the forebrain (Flora M. Vaccarino)

Jun,
22
2009

Translation factor control of stress-induced response: the role of eIF3e/Int6 andrRNA (Katsura Asano)

Jun,
25
2009

Evolution of the MHC DRA gene coding region in primates (Antoine Blancher)

Jun,
29
2009

Derived features of the Oikopleura Genome (Daniel Chourrout)

Jun,
30
2009

Novel characteristics of endogenous antisense transcripts in mammals revealed bygenome-wide expression analysis, and their functional implications (Hidenori
Kiyosawa)

Jul, 2
Mitofusinsによるミトコンドリア形態調節機構と自然免疫制御への展望（小柴琢己）
2009Jul, 6Visualising a bacterial DNA-segregation system (Jeanne Salje)
2009
Jul, 9 Developmental Insights from the Study of Newly Emerging Model Species (Nipam
2009 Pate)
Jul, 9 Evolutionary birth of a growth switch involving RTKs, Myc:Max, and ribosome
2009 biogenesis (Albert Erives)
Jul,
13
2009

DNA damage and cancer: lessons from the fruit fly (Shu Kondo)

Jul,
23
2009

B chromosomes -what makes them different? (Andreas Houben)

Jul,
27
2009

Geographic differences of Helicobacter pylori genotypes and gastric cancer (Yoshio
Yamaoka)

Jul,
28
2009

Notch and Wnt Regulation of Cardiac Progenitors (Chulan Kwon)

Jul,
30
2009

Genome wide analysis of Notch signaling in Drosophila by transgenic RNAi
(Masakazu Yamazaki)

Jul,
30
2009

Functional window of Tsix in the imprinted X-inactivation (Tatsuya Ohhata)

Jul,
31
2009

STK25 acts as a modifier of Reelin-Dab1 signaling to regulate Tau phosphorylation,neuronal polarity, and Golgi apparatus morphology (Tohru Matsuki)

Aug,
3
2009

ヘテロクロマチン領域伸長停止メカニズムの解析
boundary function) , （沖昌也）(Masaya Oki)

Aug,
19
2009

n Antarctic nematode as a model for studying genomic responses to an extreme
environment(David A. Wharton)

Aug,
25
2009

A Multiple Approach to Screening for Genes Involved in Mouse Craniofacial
Development (Minoru Kawakami)

Aug,
25
2009

Functional genomics powered by mouse inter-subspecific genome diversity(Toyoyuki Takada)

Aug,
26
2009

Structure and function of budding yeast cohesin complex (Tatsuya Nishino)

Aug,
28
2009

Chromosomes control their own segregation in mitosis (Hideki Yokoyama)

Aug,
31
2009

Evolution of retrotransposon and evolution by retrotransposon (Kenji Kojima)

Aug,
31
2009

Regulation of dominance relationships between self-incompatibility alleles via denovo DNA methylation (Yoshiaki Tarutani)

Sep,
8
2009

p31cometの新規機能：ストレス応答におけるp53の質的制御（松本智裕）

Sep,
10
2009

Optogenetic dissection of the role of cerebrospinal contacting neurons in the spinal
cord (Claire Wyart)

Sep,
15
2009

Imaging circuit assembly in the developing retina (Rachel Wong)

Sep,
28
2009

Genome-Wide Patterns in the Evolution of Gene Expression (Daniel L. Hartl)

Sep,
30
2009

Identification of direct-target genes of canonical Wnt signaling pathway in thepresomitic mesoderm responsible for somitogenesis by using ChIP-Chip method(Mitsuji Maruhashi)

Sep,
30
2009

Notch signaling regulates epithelial Clara/cilia fate selection and arterial smoothmuscle cell determination during lung organogenesis (Mitsuru Morimoto)(AnalysisofheterochromatinOct, 8 The biology of nuage: findings dropped from the clouds in germline cells (Toshie
2009 Kai)
Oct,
13
2009

Using Zebrafish Genomics to elucidate Human Disease (Thomas S Becker)

Oct,
15
2009

Global reorganization of replication domains during mouse ES cell differentiation –implications for nuclear genome architecture during development (Ichiro Hiratani)

Oct,
20
2009

Evolutionary and functional significance of human intergenic transcripts (Yasunori
Aizawa)

Oct,
20
2009

Genome-wide RNAi analysis identifies novel components of the G2/M DNA
damage checkpoint (Shu Kondo)

Oct,
20
2009

Physical control of cell shape and tissue growth in Drosophila (Takashi Hayashi)

Oct,
21
2009

Transgeneratonal genetic control of phenotypic variation and disease risk (JoeNadeau)

Oct,
26
2009

Ancient DNA researches on natural history of northern Japan (Ryuichi Masuda)

Oct,
28
2009

Nuclear myosin 1 - The muscles for DNA transcription? (Pavel Hozak)

Nov,
12
2009

The phylogenetic approach to investigating cultural evolution (Tom Currie)

Nov,
13
2009

Neurobiological mechanisms of escalated aggression: GABA receptor modulationof dorsal raphé nucleus (Aki Takahashi)

Nov,
19
2009

Controls of the frontal cortical size and the neuronal number during development(Setsuko Sahara)

Nov,
19
2009

Evolution of Eyes and Photoreceptors (Walter J. Gehring)

Nov,
20
2009

GENOME-WIDE ANALYSIS OF NATURAL SELECTION AND NEUTRAL THEORY(Masatoshi Nei)

Nov,
25
2009

Immunoglobulin Gene Conversion and Somatic Hypermutation: Regulation,
Evolution and Biotechnology (Hiroshi Arakawa)

Nov,
25
2009

π型志向人間にとっての遺伝学：新型インフルエンザウイルスのゲノム配列が変化して行く方向予測への挑戦（池村淑道）

Nov,
25
2009

Chromatin dynamics in vitro studied by atomic force microscopy (Kohji Hizume)

Dec,
1
2009

Genetic approaches to understand mechanisms of brain maturation and remodelingin nematodes and mice (Yu Hayashi)

Dec,
4
2009

Reorganization of chromatin arrangement after DNA breakage -How does achromosome architecture influence DSB repair? – (Koichi Watanabe)

Dec,
7
2009

Small RNA-directed DNA elimination in Tetrahymena (Kazufumi Mochizuki)

Dec,
7
2009

The Dynamic Genome of Hydra (Charles N. David)

Dec,
8
2009

Forward Genetic Screens in the Mouse to Discover Cancer Genes and Cancer
Pathways (David Adams)

Dec,
8
2009

Functional Strategies Shared by Invertebrate and Vertebrate Nervous Systems(Ralph Greenspan)

Dec,
8
2009

The Mouse Genomes Project: Background, Informatics
visualization (Thomas Keane)

Dec,
14
2009

The role of the Wnt/β-catenin signaling gradient in presomitic mesoderm
development (Alexander Aulehla)

Dec,
14
2009

Using quantitative genetics to understand behavior in mice and humans (Palmer
Abraham)

Dec,
14
2009

Targeted Genome Alteration Using OPEN Zinc Finger Nucleases (J. Keith Joung)

Dec,
17
2009

Reversible Mono-Ubiquitination of Smad4 Regulates TGF-β Signaling in Flies,
Frogs and Mammalian Cells (Stuart Newfeld)

Dec,
17
2009

Timing and Coordination in Flower Development- Regulation of Chromatin by aHomeotic Transcription Factor (Toshiro Ito)

Dec,
18
2009

Symmetry breaking in C. elegans zygote (Fumio Motegi)

Dec,
21
2009

Live cell imaging of Xic homologous pairing in mouse ES cells : implications for the
initiation of X chromosome inactivation (Osamu Masui)

Dec,
28
2009

Live-Watching TE Burst: The Behavior and the Impact. (Ken Naito)

Dec,
28
2009

A characterstic role for anti-oxidant responses of the cochlear melanocytes
essential for hearing acuity (Shigeyuki Uehara)

Challenges, andJan, 7 Self-organisation and ordered pattern of nuclei in syncytial embryo of Drosophila
2010 (Takuma Kanesaki)Jan, 8 A role of ultrasonic vocalizations for mating behavior in mice (Hiroki Sugimoto)
2010
Jan,
15
2010

Tempo and Mode of Chloroplast Evolution, and Seed Plant Phylogeny (Masami
Hasegawa)

Jan,
20
2010

Inheritance of organellar DNAs in higher plants: cytological and genetic studies on
discriminating organellar DNAs in male gametophytes (Wataru Sakamoto)

Jan,
26
2010

Isolation and Characterization of the Swi5/Sfr1 complex in mice (Yufuko Akamatsu)

Feb,
1
2010

Frontiers of Science (Barbara R. Jasny)

Feb,
8
2010

A mathematical model of bacterial plasmid partitioning (Takeshi Sugawara)

Feb,
8
2010

Bacterial mRNA dynamics: Inter-relationships between transcript synthesis,
transcript termination, translation, and mRNA degradation (Growrishankar, J)

Feb,
10
2010

Genetic Diversity and Association Study in Japanese Rice Cultivars (Masanori
Yamasaki)

Feb,
10
2010

Conservation of developmental mechanisms in evolutionarily divergent brain
structures (Ikuo Suzuki)

Feb,
15
2010

Analysis of motif sequences for binding to human REV7 and MAD2 proteins (TomoHanafusa)

Feb,
18
2010

脂質２分子膜小胞の変形の膜弾性モデルを用いた理論解析（梅田民樹）

Feb,
22
2010

Analyses of mitosis and meiosis using interspecific hybrids in the medaka fish(Oryzias latipes) (Chiharu Sakai)

Mar,
2
2010

RNA editing in plant organelles: Correlation between editing sites and protein threedimensional structures, and prediction of RNA editing sites (Kei Yura)

Mar,
4
2010

Development and application of package software for molecular dynamics (MD)simulation (Munetaka Takeuchi)

Mar,
5
2010

Analysis of the factors that affect efficient induction of heritable transcriptional genesilencing through Cucumber mosaic virus infection (Shungo Otagaki)

Mar,
11
2010

Arousal regulation by sensory stimuli and neuromodulators in C. elegans (Yoshinori
Tanizawa)

Mar,
12
2010

Direct visualization of endosomal escape oflipid-coated beads by live CLEM
(Shouhei Kobayashi)

Mar,
23
2010

3D/4D interactive visualization tools for confocal microscopy (Hideo Otsuna)

Mar,
30
2010

Controls of germline self-renewal and differentiation in C. elegans (Judith Kimble)

Mar,
31
2010

Mechanisms of mRNA control: Finding the mRNA and controlling its fate (Marvin
Wickens)backAnnual Report 2009

No. 60back

Foreign Visitors
Apr, 17 Miho2009
MatsudaNeural Developmental Dynamics LMG, NICHD, NIH, USA

May, 20 Takeshi
2009
Awasaki

University of Massachusetts Medical School

May, 26
Hayato Yokoi Institute of Neuroscience, University of Oregon
2009Jun, 5
Bianca Sclavi CNRS/Ecole Normale Superieure de Cachan, FRANCE
2009
Jun, 8 Jerzy2009
Paszkowski

University Of Geneva

Jun, 11Jeffrey Chen
2009

University of Texas

Jun, 11
Tzumin Lee
2009

University of Massachusetts Medical School and Janelia Farm,
HHMI

Jun, 22 Flora
M.
Yale University School of Medicine
2009
VaccarinoJun, 22 Katsura
2009
Asano

Division of Biology, Kansas State University

Jun, 25 Antoine
2009
Blancher

Universite Paul Sabatier, Hopital Rangueil Toulouse FRANCE

Jun, 29 Daniel
2009
ChourroutSars International Center for Marine Molecular Biology, Universityof Bergen, Norway

Jul,
6
MRC Laboratory ofJeanne Salja
2009
University

Molecular

Biology,Cambridge/Kyoto

Jul,
9
Albert Erives Dept. of Biological Sciences, Dartmouth College
2009
Jul,
9
Nipam Patel2009

University of California, Berkeley Departments of Molecular Cell
Biology and Integrative Biology

Jul, 13
Shu Kondo
2009

Harvard Medical School, Department of Genetics

Jul, 23 Andreas
2009
HoubenLeibniz Institute for Plant Genetics and Crop Plant Research
Gatersleben, Germany

Jul, 28
Gladstone Institute of Cardiovascular Disease University of
Chulan Kwon California San Francisco
2009Jul, 30 Tatsuya
2009
OhhataResearch Institute of Molecular Pathology, Vienna, Austria

Jul, 31 Tohru
2009
MatsukiAug, 19 David2009
WhartonState University of New York, Upstate Medical University
A.

Department Zoology, University of Otago

Aug, 28 Hideki
2009
Yokoyama

EMBL, Cell Biology Unit, Heidelberg, Germany

Sep, 1Claire Wyart
2009

UC Berkeley, USA

Sep, 15
Rachel Wong Dept. Biological Structure, University of Washington
2009
Sep, 28 Daniel
2009
Hartl

L. Department of Organismic & Evolutionary Biology, Harvard
University

Sep, 30 Mitsuji
2009Maruhashi

Howard Hughes Medical Institute Stowers Institute for Medical
ResearchSep, 30 Mitsuru
2009
Morimoto

Department of Developmental Biology, Washington University in
St. Louis

Oct, 1 Yoshiteru
2009
Sato

Institute of Genetics and Molecular and Cellular Biology (IGBMC)

Oct, 8
Toshie Kai
2009

Temasek Life Science Laboratory, Singapore

Oct, 13 Thomas
2009
Becker

S The Brain and Mind Research Institute, University of Sydney,
Australia

Oct, 15David Gilbert Laboratory, Department of Biological Science,
Ichiro Hiratani
2009
Florida State University
Oct, 20
Shu Kondo
2009

Department of Genetics, Harvard Medical School

Oct, 21
Joe Nadeau
2009

Dept. of Genetics, Case Western Reserve University, Cleveland

Oct, 28
Pavel Hozak
2009

Institute of Molecular Genetics, Prague, Academy of Sciences of
the Czech RepublicNov, 13 Aki
2009
Takahashi

Department of Psychology Tufts University, USA

Nov, 19 Setsuko
2009
SaharaThe Salk Institute for Biological Studies

Nov, 19 Walter
2009
GehringJ.

Biozentrum, University of BaselNov, 20 Masatoshi
2009
Nei

Pennsylvania State University

Nov, 25 Hiroshi
2009
Arakawa

Helmholtz Center Munich,Enviromental HealthDec, 4 Koichi
2009
Watanabe

Leibniz Institute for Plant Genetics and Crop Plant Research

German Research CenterforDec, 7 Charles
2009
David

N. Ludwig-Maximilians University

Dec, 7 Kazufumi
2009
Mochizuki

IMBA, Wien

Dec, 8David Adams Wellcome Trust Sanger Institute, UK
2009
Dec, 8 Ralph
2009
Greenspan

The Neuroscience Institute, USA

Dec, 8 Thomas
2009
Keane

Wellcome Trust Sanger Institute, UK

Dec, 14 Alexander
2009
Aulehla

EMBL, Heidelberg

Dec, 14 J.
2009
Joung

Harvard Medical School

Keith

Dec, 14 Palmer
2009
Abraham

Department of Human Genetics, University of Chicago

Dec, 17
Toshiro Ito
2009

Temasek Life Science Laboratory, National University ofSingaporeDec, 17 Stuart
2009
Newfeld

School of Life Science, Arizona State University

Dec, 18 Fumio
2009
MotegiJohns Hopkins University School of Medicine, HHMI

Dec, 21 Osamu
2009
Masui

Mammalian Developmental Epigenetics
UMR3215/INSERMU934, Curie InstituteDec, 28
Ken Naito
2009

Plant Science, University of Georgia

Jan, 7 Takuma
2010
KanesakiDepartment of Developmental Biochemistry, Faculty of Medicine
Georg-August Universitat Gottingen

Jan, 15 Msami
2010
Hasegawa

School of Life Sciences, Fudan University

Jan, 26 Yufuko
2010
Akamatsu

Memorial Sloan-Kettering Cancer Center

Feb, 1 Barbara
2010
Jasny

R.

Group,CNRS

Deputy Editor for Commentary, Science/AAAS

Feb, 8 Gowrishanjar,
Center for DNA Fingerprinting and Diagnositics, Hyderabad, India
2010
J.
Mar, 11 Yoshinori
2010
Tanizawa

MAC Laboratory of Molecular Biology, Cell Biology Division,
Cambridge, England

Mar, 23
Hideo Otsuna University of Utah, Neurobiology and Anatomy
2010
Mar, 30
Judith Kimble University of Wisconsin, Department of Biochemistry
2010
Mar, 31 Marvin
2010
Wickens

University of Wisconsin, Department of Biochemistry

back